locus-tag	class	description
FR741_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FR741_00025	COG1126	abc transporter atp-binding protein
FR741_00035	COG0594	ribonuclease P activity
FR741_00045	COG0706	membrane insertase activity
FR741_00055	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FR741_00060	COG0445	tRNA wobble uridine modification
FR741_00065	COG0357	Ribosomal RNA small subunit methyltransferase G
FR741_00070	COG1192	Involved in chromosome partitioning
FR741_00075	COG1475	DNA binding
FR741_00080	COG3312	ion transport
FR741_00085	COG0356	it plays a direct role in the translocation of protons across the membrane
FR741_00095	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FR741_00100	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FR741_00105	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FR741_00110	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FR741_00115	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FR741_00120	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FR741_00130	COG0765	amino acid transport
FR741_00140	COG2814	Major facilitator Superfamily
FR741_00145	COG0583	DNA-binding transcription factor activity
FR741_00155	COG0129	dihydroxy-acid dehydratase activity
FR741_00160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FR741_00165	COG3978	acetolactate synthase activity
FR741_00175	COG0606	chelatase, subunit chli
FR741_00185	COG0204	Acyl-transferase
FR741_00190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR741_00195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FR741_00205	COG3084	Protein conserved in bacteria
FR741_00215	COG4326	sporulation control protein
FR741_00220	COG1272	protein, Hemolysin III
FR741_00230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FR741_00235	COG0569	domain protein
FR741_00240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FR741_00240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FR741_00245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FR741_00250	COG0242	peptide deformylase activity
FR741_00260	COG0758	DNA mediated transformation
FR741_00265	COG2922	Belongs to the Smg family
FR741_00270	COG0551	DNA topoisomerase type I activity
FR741_00275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FR741_00280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FR741_00285	COG0009	L-threonylcarbamoyladenylate synthase
FR741_00290	COG0408	coproporphyrinogen oxidase activity
FR741_00295	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FR741_00305	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FR741_00355	COG2132	Multicopper oxidase
FR741_00360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FR741_00375	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FR741_00395	COG0006	proline dipeptidase activity
FR741_00395	COG0006	proline dipeptidase activity
FR741_00425	COG3220	belongs to the UPF0276 family
FR741_00435	COG0210	DNA helicase
FR741_00445	COG0405	Gamma-glutamyltransferase
FR741_00450	COG1280	lysine exporter protein (LysE YggA)
FR741_00460	COG2962	Rard protein
FR741_00465	COG0514	ATP-dependent DNA helicase (RecQ)
FR741_00475	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FR741_00480	COG0248	Ppx GppA phosphatase
FR741_00485	COG0513	Belongs to the DEAD box helicase family
FR741_00490	COG3118	belongs to the thioredoxin family
FR741_00505	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FR741_00510	COG0633	Ferredoxin
FR741_00555	COG3071	HemY protein
FR741_00560	COG2959	enzyme of heme biosynthesis
FR741_00565	COG1587	Uroporphyrinogen-III synthase
FR741_00570	COG0181	hydroxymethylbilane synthase activity
FR741_00575	COG3072	Adenylate cyclase
FR741_00580	COG1965	Belongs to the frataxin family
FR741_00590	COG0019	diaminopimelate decarboxylase activity
FR741_00595	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FR741_00605	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FR741_00610	COG1011	Hydrolase
FR741_00615	COG2199	diguanylate cyclase activity
FR741_00615	COG2200	EAL domain
FR741_00615	COG3287	FIST C domain
FR741_00635	COG0561	phosphatase activity
FR741_00640	COG2267	carboxylic ester hydrolase activity
FR741_00645	COG1280	lysine exporter protein (LysE YggA)
FR741_00650	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FR741_00655	COG0640	Transcriptional regulator
FR741_00660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FR741_00710	COG2095	MarC family integral membrane protein
FR741_00720	COG0742	ribosomal rna small subunit methyltransferase
FR741_00725	COG0552	protein localization to endoplasmic reticulum
FR741_00730	COG2884	Cell division ATP-binding protein ftsE
FR741_00735	COG2177	Part of the ABC transporter FtsEX involved in
FR741_00750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR741_00755	COG0705	Rhomboid family
FR741_00760	COG1580	Controls the rotational direction of flagella during chemotaxis
FR741_00765	COG3161	chorismate lyase activity
FR741_00770	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FR741_00775	COG2937	Belongs to the GPAT DAPAT family
FR741_00785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FR741_00795	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FR741_00800	COG0534	Mate efflux family protein
FR741_00805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR741_00825	COG4206	TonB-dependent receptor
FR741_00890	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR741_00900	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FR741_00905	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FR741_00905	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FR741_00940	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FR741_00950	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FR741_00955	COG0250	Participates in transcription elongation, termination and antitermination
FR741_00970	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FR741_00975	COG0222	ribosome binding
FR741_00980	COG0085	RNA polymerase activity
FR741_00985	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FR741_00990	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FR741_00995	COG2816	NAD+ diphosphatase activity
FR741_01000	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FR741_01005	COG1573	uracil-dna glycosylase
FR741_01015	COG3068	Protein conserved in bacteria
FR741_01020	COG1253	flavin adenine dinucleotide binding
FR741_01035	COG0151	Belongs to the GarS family
FR741_01045	COG0138	bifunctional purine biosynthesis protein purh
FR741_01055	COG0789	Transcriptional regulator
FR741_01060	COG3710	Transcriptional regulator
FR741_01070	COG0531	amino acid
FR741_01075	COG1982	Orn Lys Arg decarboxylase major
FR741_01140	COG0488	(ABC) transporter
FR741_01150	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FR741_01155	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR741_01160	COG2264	protein methyltransferase activity
FR741_01170	COG0439	Biotin carboxylase
FR741_01175	COG0511	ligase activity, forming carbon-carbon bonds
FR741_01180	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FR741_01185	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FR741_01200	COG2814	Major facilitator Superfamily
FR741_01225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR741_01235	COG3263	regulation of cellular component size
FR741_01245	COG4232	protein-disulfide reductase activity
FR741_01250	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FR741_01255	COG1027	Aspartate ammonia-lyase
FR741_01260	COG3030	protein affecting phage T7 exclusion by the F plasmid
FR741_01265	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FR741_01275	COG2205	protein histidine kinase activity
FR741_01280	COG0745	RESPONSE REGULATOR receiver
FR741_01285	COG3678	ATP-independent chaperone mediated protein folding
FR741_01290	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FR741_01295	COG0205	6-phosphofructokinase activity
FR741_01300	COG0534	Mate efflux family protein
FR741_01310	COG0459	protein refolding
FR741_01320	COG1285	pathogenesis
FR741_01325	COG1509	lysine 2,3-aminomutase activity
FR741_01345	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FR741_01350	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FR741_01355	COG1053	succinate dehydrogenase
FR741_01360	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FR741_01380	COG4942	peptidase
FR741_01385	COG1045	serine acetyltransferase
FR741_01390	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FR741_01395	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FR741_01400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR741_01405	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FR741_01415	COG3273	potassium ion transport
FR741_01415	COG0471	metal ion transport
FR741_01420	COG0688	phosphatidylethanolamine metabolic process
FR741_01425	COG1162	GTPase activity
FR741_01430	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FR741_01495	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FR741_01505	COG0802	atpase or kinase
FR741_01515	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FR741_01520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FR741_01530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FR741_01535	COG0330	HflC and HflK could
FR741_01540	COG0330	HflC and HflK could
FR741_01545	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FR741_01550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FR741_01560	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FR741_01565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR741_01565	COG1017	nitric oxide dioxygenase activity
FR741_01570	COG1959	2 iron, 2 sulfur cluster binding
FR741_01575	COG0557	exoribonuclease II activity
FR741_01580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR741_01585	COG0546	phosphoglycolate phosphatase activity
FR741_01590	COG0180	Tryptophanyl-tRNA synthetase
FR741_01605	COG0512	Glutamine amidotransferase of anthranilate synthase
FR741_01610	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FR741_01630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR741_01635	COG3954	Phosphoribulokinase
FR741_01640	COG3089	Belongs to the UPF0270 family
FR741_01645	COG0429	hydrolase of the alpha beta-hydrolase fold
FR741_01655	COG0488	(ABC) transporter
FR741_01660	COG2249	NAD(P)H dehydrogenase (quinone) activity
FR741_01675	COG1047	Peptidyl-prolyl cis-trans
FR741_01680	COG1446	asparaginase
FR741_01695	COG0545	Peptidyl-prolyl cis-trans isomerase
FR741_01700	COG2964	Protein conserved in bacteria
FR741_01705	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FR741_01710	COG2923	Belongs to the DsrF TusC family
FR741_01715	COG2168	tRNA wobble position uridine thiolation
FR741_01730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FR741_01735	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FR741_01740	COG2906	2 iron, 2 sulfur cluster binding
FR741_01750	COG0281	malic enzyme
FR741_01760	COG0626	cystathionine gamma-synthase activity
FR741_01765	COG0527	aspartate kinase activity
FR741_01765	COG0460	homoserine dehydrogenase
FR741_01770	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FR741_01780	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FR741_01790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FR741_01800	COG0137	argininosuccinate synthase activity
FR741_01805	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FR741_01805	COG0165	Argininosuccinate lyase
FR741_01825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FR741_01825	COG0678	peroxiredoxin activity
FR741_01840	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FR741_01870	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FR741_01875	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FR741_01885	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FR741_01890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FR741_01895	COG0360	Binds together with S18 to 16S ribosomal RNA
FR741_01900	COG2965	DNA replication, synthesis of RNA primer
FR741_01925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FR741_01930	COG0432	Pfam Uncharacterised protein family UPF0047
FR741_01935	COG0166	Belongs to the GPI family
FR741_01945	COG0735	belongs to the Fur family
FR741_01950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR741_01970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FR741_01975	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR741_01980	COG0175	sulfate reduction
FR741_02045	COG0646	methionine synthase
FR741_02045	COG1410	methionine synthase
FR741_02050	COG0527	aspartate kinase activity
FR741_02060	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FR741_02070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FR741_02085	COG0629	single-stranded DNA binding
FR741_02115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR741_02145	COG3550	peptidyl-serine autophosphorylation
FR741_02180	COG2200	EAL domain
FR741_02180	COG2199	diguanylate cyclase activity
FR741_02200	COG1450	Type ii and iii secretion system protein
FR741_02205	COG3267	Type II secretory pathway component ExeA
FR741_02205	COG3409	Peptidoglycan-binding domain 1 protein
FR741_02215	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FR741_02220	COG1459	type II secretion system
FR741_02265	COG1077	Cell shape determining protein MreB Mrl
FR741_02270	COG1792	Involved in formation and maintenance of cell shape
FR741_02275	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FR741_02280	COG0424	maF-like protein
FR741_02285	COG1530	ribonuclease E activity
FR741_02290	COG3164	Protein of unknown function
FR741_02295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FR741_02300	COG0312	modulator of DNA gyrase
FR741_02305	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FR741_02310	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FR741_02320	COG0564	pseudouridine synthase activity
FR741_02325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FR741_02330	COG3028	Belongs to the UPF0307 family
FR741_02335	COG0312	modulator of DNA gyrase
FR741_02340	COG2239	Acts as a magnesium transporter
FR741_02345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR741_02350	COG1660	Displays ATPase and GTPase activities
FR741_02355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR741_02360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FR741_02370	COG1137	ATPase activity
FR741_02375	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FR741_02385	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FR741_02385	COG0517	IMP dehydrogenase activity
FR741_02395	COG1127	ABC transporter
FR741_02400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FR741_02405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FR741_02410	COG2854	intermembrane phospholipid transfer
FR741_02420	COG5007	Belongs to the BolA IbaG family
FR741_02430	COG0204	Acyl-transferase
FR741_02435	COG0251	oxidation-reduction process
FR741_02440	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FR741_02445	COG0540	Belongs to the ATCase OTCase family
FR741_02485	COG0525	valine-tRNA ligase activity
FR741_02490	COG2927	DNA polymerase III (CHI subunit)
FR741_02500	COG0795	lipopolysaccharide-transporting ATPase activity
FR741_02505	COG0795	lipopolysaccharide-transporting ATPase activity
FR741_02520	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_02530	COG0726	polysaccharide deacetylase
FR741_02540	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR741_02545	COG1447	Phosphotransferase system cellobiose-specific component IIA
FR741_02550	COG1486	melibiose metabolic process
FR741_02555	COG3394	polysaccharide catabolic process
FR741_02565	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FR741_02615	COG1012	belongs to the aldehyde dehydrogenase family
FR741_02690	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FR741_02700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FR741_02710	COG2066	Belongs to the glutaminase family
FR741_02715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FR741_02720	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FR741_02730	COG1872	DUF167
FR741_02735	COG0762	integral membrane protein
FR741_02740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FR741_02745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FR741_02760	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FR741_02765	COG1678	Uncharacterized ACR, COG1678
FR741_02770	COG0189	ligase activity
FR741_02775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FR741_02780	COG2356	endonuclease I
FR741_02795	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FR741_02805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FR741_02810	COG0583	DNA-binding transcription factor activity
FR741_02815	COG4771	TonB-dependent receptor
FR741_02825	COG0126	phosphoglycerate kinase activity
FR741_02830	COG0191	fructose-bisphosphate aldolase activity
FR741_02835	COG0668	transmembrane transport
FR741_02850	COG0583	DNA-binding transcription factor activity
FR741_02860	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FR741_02865	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FR741_02870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FR741_02880	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FR741_02890	COG3079	Belongs to the UPF0149 family
FR741_02895	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR741_02900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR741_02915	COG0354	folic acid binding
FR741_02920	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FR741_02930	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FR741_02940	COG1595	DNA-templated transcription, initiation
FR741_02955	COG3086	response to oxidative stress
FR741_02960	COG0481	GTPase activity
FR741_02965	COG0681	Belongs to the peptidase S26 family
FR741_02975	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FR741_02980	COG1381	Involved in DNA repair and RecF pathway recombination
FR741_02985	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FR741_02990	COG0736	holo-[acyl-carrier-protein] synthase activity
FR741_03005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FR741_03015	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FR741_03020	COG3956	TIGRFAM MazG family protein
FR741_03025	COG0504	CTP synthase activity
FR741_03030	COG0148	phosphopyruvate hydratase activity
FR741_03035	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FR741_03040	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FR741_03045	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FR741_03055	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FR741_03060	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FR741_03070	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FR741_03075	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FR741_03080	COG1546	Belongs to the CinA family
FR741_03085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FR741_03090	COG2137	regulation of response to DNA damage stimulus
FR741_03095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FR741_03100	COG0527	aspartate kinase activity
FR741_03165	COG3630	sodium ion export across plasma membrane
FR741_03170	COG0511	ligase activity, forming carbon-carbon bonds
FR741_03170	COG5016	pyruvate
FR741_03175	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FR741_03185	COG1238	metal cluster binding
FR741_03190	COG0612	Peptidase, M16
FR741_03205	COG1854	S-ribosylhomocysteine lyase activity
FR741_03210	COG4536	flavin adenine dinucleotide binding
FR741_03215	COG4137	Cytochrome C assembly protein
FR741_03220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FR741_03225	COG0228	four-way junction DNA binding
FR741_03230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FR741_03245	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FR741_03250	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FR741_03255	COG0237	dephospho-CoA kinase activity
FR741_03265	COG1459	type II secretion system
FR741_03270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FR741_03275	COG4969	Belongs to the N-Me-Phe pilin family
FR741_03285	COG0157	Belongs to the NadC ModD family
FR741_03295	COG2186	Transcriptional regulator
FR741_03300	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FR741_03305	COG0508	dehydrogenase complex catalyzes the overall conversion of
FR741_03310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR741_03325	COG0288	reversible hydration of carbon dioxide
FR741_03330	COG0659	secondary active sulfate transmembrane transporter activity
FR741_03335	COG1131	(ABC) transporter
FR741_03340	COG0842	Transport permease protein
FR741_03350	COG1560	Kdo2-lipid A biosynthetic process
FR741_03355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FR741_03360	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FR741_03365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FR741_03375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FR741_03385	COG1489	DNA binding
FR741_03390	COG1643	Atp-dependent helicase
FR741_03395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FR741_03400	COG1752	Esterase of the alpha-beta hydrolase superfamily
FR741_03405	COG1049	propionate catabolic process, 2-methylcitrate cycle
FR741_03410	COG3112	Uncharacterised protein family (UPF0231)
FR741_03415	COG0347	Belongs to the P(II) protein family
FR741_03420	COG0004	ammonium transporteR
FR741_03425	COG1840	ABC-type Fe3 transport system, periplasmic component
FR741_03435	COG3842	ATPase activity
FR741_03440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FR741_03455	COG2971	BadF BadG BcrA BcrD
FR741_03465	COG4608	Belongs to the ABC transporter superfamily
FR741_03470	COG0444	Belongs to the ABC transporter superfamily
FR741_03485	COG0747	negative chemotaxis
FR741_03490	COG2205	protein histidine kinase activity
FR741_03490	COG0784	Response regulator, receiver
FR741_03500	COG0628	permease
FR741_03505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FR741_03525	COG0739	heme binding
FR741_03530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FR741_03540	COG2027	D-alanyl-D-alanine carboxypeptidase
FR741_03545	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR741_03550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FR741_03555	COG1534	Rna-binding protein
FR741_03560	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FR741_03565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FR741_03570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FR741_03575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FR741_03585	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FR741_03600	COG0779	Required for maturation of 30S ribosomal subunits
FR741_03605	COG0195	Participates in both transcription termination and antitermination
FR741_03610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FR741_03615	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FR741_03620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FR741_03625	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FR741_03630	COG1185	polyribonucleotide nucleotidyltransferase activity
FR741_03645	COG0534	Mate efflux family protein
FR741_03650	COG0826	peptidase U32
FR741_03655	COG0826	peptidase U32
FR741_03670	COG3154	lipid carrier protein
FR741_03675	COG3153	acetyltransferase
FR741_03695	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FR741_03705	COG0084	hydrolase, TatD family'
FR741_03710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR741_03725	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FR741_03730	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FR741_03735	COG0813	purine-nucleoside phosphorylase activity
FR741_03745	COG0560	Phosphoserine phosphatase
FR741_03755	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FR741_03760	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FR741_03765	COG0583	DNA-binding transcription factor activity
FR741_03775	COG1022	Amp-dependent synthetase and ligase
FR741_03780	COG2169	Transcriptional regulator
FR741_03805	COG4964	Belongs to the GSP D family
FR741_03865	COG0583	DNA-binding transcription factor activity
FR741_03870	COG0531	amino acid
FR741_03875	COG2731	YhcH YjgK YiaL family protein
FR741_03880	COG3250	beta-galactosidase activity
FR741_03885	COG1609	Transcriptional regulator
FR741_03895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FR741_03905	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FR741_03910	COG2017	converts alpha-aldose to the beta-anomer
FR741_03915	COG1609	Transcriptional regulator
FR741_03925	COG2211	Major facilitator Superfamily
FR741_03930	COG1609	Transcriptional regulator
FR741_03935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR741_03955	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FR741_03960	COG1349	DNA-binding transcription factor activity
FR741_03965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FR741_03970	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FR741_03980	COG2271	Major facilitator Superfamily
FR741_03985	COG0584	glycerophosphoryl diester phosphodiesterase
FR741_03990	COG2171	N-acyltransferase activity
FR741_03995	COG3141	response to X-ray
FR741_04015	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FR741_04025	COG1074	ATP-dependent DNA helicase activity
FR741_04030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FR741_04040	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FR741_04040	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FR741_04055	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FR741_04060	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FR741_04065	COG2166	iron-sulfur cluster assembly
FR741_04070	COG3706	GGDEF domain
FR741_04075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FR741_04080	COG0693	protein deglycase activity
FR741_04085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FR741_04090	COG3248	Nucleoside-binding outer membrane protein
FR741_04110	COG1595	DNA-templated transcription, initiation
FR741_04130	COG3056	Lipoprotein
FR741_04135	COG2813	Specifically methylates the guanine in position
FR741_04140	COG0271	Belongs to the BolA IbaG family
FR741_04145	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR741_04150	COG1805	sodium ion transport
FR741_04155	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR741_04160	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR741_04165	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FR741_04170	COG2871	sodium ion transport
FR741_04175	COG1477	protein flavinylation
FR741_04190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FR741_04195	COG0514	ATP-dependent DNA helicase (RecQ)
FR741_04215	COG0733	neurotransmitter:sodium symporter activity
FR741_04235	COG0442	prolyl-tRNA aminoacylation
FR741_04240	COG1720	tRNA m6t6A37 methyltransferase activity
FR741_04245	COG0254	rRNA binding
FR741_04255	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FR741_04280	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FR741_04285	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FR741_04320	COG0564	pseudouridine synthase activity
FR741_04330	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FR741_04335	COG0024	Methionine aminopeptidase
FR741_04340	COG0052	Belongs to the universal ribosomal protein uS2 family
FR741_04345	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FR741_04350	COG0528	UMP kinase activity
FR741_04355	COG0233	cytoplasmic translational termination
FR741_04360	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FR741_04365	COG0575	Belongs to the CDS family
FR741_04370	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FR741_04375	COG0750	zinc metalloprotease
FR741_04385	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FR741_04390	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR741_04400	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR741_04405	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR741_04415	COG0587	DNA-directed DNA polymerase activity
FR741_04420	COG0825	malonyl-CoA metabolic process
FR741_04435	COG0347	Belongs to the P(II) protein family
FR741_04440	COG3021	interspecies interaction between organisms
FR741_04450	COG1388	LysM domain
FR741_04450	COG0741	lytic transglycosylase activity
FR741_04455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR741_04460	COG2226	methyltransferase
FR741_04465	COG0328	RNA-DNA hybrid ribonuclease activity
FR741_04505	COG1960	acyl-CoA dehydrogenase activity
FR741_04515	COG0121	glutamine amidotransferase
FR741_04520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FR741_04525	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FR741_04530	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FR741_04535	COG2233	PERMEase
FR741_04555	COG4783	chaperone-mediated protein folding
FR741_04570	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FR741_04580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR741_04600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FR741_04605	COG1393	Belongs to the ArsC family
FR741_04630	COG2837	iron assimilation
FR741_04635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR741_04645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR741_04650	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR741_04655	COG1334	flagellar protein FlaG
FR741_04660	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FR741_04670	COG1516	flagellar protein fliS
FR741_04680	COG4191	Histidine kinase
FR741_04690	COG1677	Flagellar hook-basal body complex protein FliE
FR741_04700	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FR741_04750	COG1987	bacterial-type flagellum assembly
FR741_04755	COG1684	flagellar biosynthetic protein fliR
FR741_04790	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FR741_04795	COG0643	Histidine kinase
FR741_04795	COG0784	Response regulator, receiver
FR741_04795	COG2198	Histidine kinase
FR741_04800	COG2201	protein-glutamate methylesterase activity
FR741_04805	COG1192	Involved in chromosome partitioning
FR741_04815	COG0835	chemotaxis
FR741_04825	COG4133	protoheme IX ABC transporter activity
FR741_04830	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FR741_04835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FR741_04840	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FR741_04845	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FR741_04850	COG1138	Cytochrome C-type biogenesis protein
FR741_04855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FR741_04875	COG2067	long-chain fatty acid transport protein
FR741_04895	COG0183	Belongs to the thiolase family
FR741_04900	COG1250	3-hydroxyacyl-CoA dehydrogenase
FR741_04900	COG1024	Enoyl-CoA hydratase
FR741_04915	COG2062	phosphohistidine phosphatase, SixA
FR741_04920	COG2840	Smr protein MutS2
FR741_04925	COG2890	protein-(glutamine-N5) methyltransferase activity
FR741_04935	COG2860	membrane
FR741_04945	COG3101	peptidyl-lysine hydroxylation
FR741_04960	COG0431	NADPH-dependent FMN reductase
FR741_04965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FR741_04965	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FR741_04970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FR741_04980	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FR741_04985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FR741_04995	COG0101	tRNA pseudouridine synthase activity
FR741_05005	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FR741_05010	COG0285	dihydrofolate synthase activity
FR741_05015	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FR741_05020	COG1286	toxin biosynthetic process
FR741_05025	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FR741_05030	COG0583	DNA-binding transcription factor activity
FR741_05035	COG0745	RESPONSE REGULATOR receiver
FR741_05045	COG2832	Protein of unknown function (DUF454)
FR741_05050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FR741_05065	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FR741_05080	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FR741_05085	COG0814	amino acid
FR741_05090	COG0251	oxidation-reduction process
FR741_05095	COG3681	Belongs to the UPF0597 family
FR741_05110	COG2261	transglycosylase associated protein
FR741_05115	COG2983	Belongs to the UPF0260 family
FR741_05120	COG0668	transmembrane transport
FR741_05125	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FR741_05130	COG0346	lactoylglutathione lyase activity
FR741_05140	COG1785	Belongs to the alkaline phosphatase family
FR741_05160	COG2226	methyltransferase
FR741_05175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FR741_05180	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR741_05190	COG3139	Protein of unknown function (DUF1315)
FR741_05195	COG0252	asparaginase activity
FR741_05200	COG0616	signal peptide processing
FR741_05205	COG0446	pyridine nucleotide-disulphide oxidoreductase
FR741_05205	COG1902	pentaerythritol trinitrate reductase activity
FR741_05215	COG0778	Nitroreductase
FR741_05220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FR741_05235	COG0123	including yeast histone deacetylase and acetoin utilization protein
FR741_05250	COG3082	Protein of unknown function (DUF1414)
FR741_05255	COG3081	Nucleoid-associated protein
FR741_05270	COG1757	Na H antiporter
FR741_05275	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FR741_05280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR741_05285	COG2095	MarC family integral membrane protein
FR741_05290	COG1012	belongs to the aldehyde dehydrogenase family
FR741_05290	COG1454	alcohol dehydrogenase
FR741_05310	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FR741_05320	COG2056	Na+-H+ antiporter family
FR741_05325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FR741_05335	COG2885	chlorophyll binding
FR741_05345	COG0346	lactoylglutathione lyase activity
FR741_05350	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FR741_05355	COG4660	Part of a membrane complex involved in electron transport
FR741_05360	COG4659	FMN binding
FR741_05365	COG4658	electron transport chain
FR741_05370	COG4656	Part of a membrane complex involved in electron transport
FR741_05375	COG2878	Part of a membrane complex involved in electron transport
FR741_05380	COG4657	Part of a membrane complex involved in electron transport
FR741_05390	COG0556	nucleotide-excision repair
FR741_05395	COG2204	response regulator
FR741_05400	COG2198	Histidine kinase
FR741_05405	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FR741_05410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FR741_05415	COG0521	Mo-molybdopterin cofactor biosynthetic process
FR741_05420	COG0315	cyclic pyranopterin monophosphate synthase activity
FR741_05425	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FR741_05430	COG0314	molybdopterin synthase activity
FR741_05440	COG0601	transmembrane transport
FR741_05445	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR741_05450	COG0444	Belongs to the ABC transporter superfamily
FR741_05460	COG0435	Glutathione S-transferase
FR741_05470	COG3174	membrane
FR741_05475	COG0857	belongs to the CobB CobQ family
FR741_05475	COG0280	phosphate acetyltransferase
FR741_05480	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FR741_05485	COG3092	negative regulation of chromosome organization
FR741_05495	COG4120	Belongs to the binding-protein-dependent transport system permease family
FR741_05500	COG1122	ATPase activity
FR741_05505	COG0366	Alpha amylase catalytic
FR741_05510	COG3706	GGDEF domain
FR741_05515	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FR741_05520	COG0653	protein targeting
FR741_05525	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FR741_05530	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FR741_05535	COG2186	Transcriptional regulator
FR741_05545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR741_05545	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR741_05555	COG0572	uridine kinase
FR741_05565	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FR741_05570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FR741_05575	COG0659	secondary active sulfate transmembrane transporter activity
FR741_05585	COG1530	ribonuclease E activity
FR741_05590	COG0564	pseudouridine synthase activity
FR741_05595	COG0424	maF-like protein
FR741_05600	COG1399	metal-binding, possibly nucleic acid-binding protein
FR741_05610	COG0416	fatty acid biosynthetic process
FR741_05615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FR741_05645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FR741_05650	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FR741_05655	COG0470	DNA polymerase III
FR741_05660	COG0084	hydrolase, TatD family'
FR741_05665	COG1263	PTS System
FR741_05665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR741_05680	COG0733	neurotransmitter:sodium symporter activity
FR741_05695	COG4667	esterase of the alpha-beta hydrolase superfamily
FR741_05700	COG0469	pyruvate kinase activity
FR741_05705	COG1940	carbohydrate kinase activity
FR741_05710	COG0784	Response regulator, receiver
FR741_05710	COG0835	chemotaxis
FR741_05715	COG0587	DNA-directed DNA polymerase activity
FR741_05730	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_05735	COG0616	signal peptide processing
FR741_05740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FR741_05745	COG0539	negative regulation of cytoplasmic translation
FR741_05755	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FR741_05760	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FR741_05770	COG4166	transmembrane transport
FR741_05785	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FR741_05785	COG3008	intermembrane lipid transfer
FR741_05790	COG2995	paraquat-inducible protein a
FR741_05795	COG3258	Cytochrome c
FR741_05800	COG2863	cytochrome
FR741_05835	COG4232	protein-disulfide reductase activity
FR741_05840	COG3118	belongs to the thioredoxin family
FR741_05870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR741_05880	COG1136	(ABC) transporter
FR741_05880	COG0577	efflux transmembrane transporter activity
FR741_05890	COG0577	efflux transmembrane transporter activity
FR741_05890	COG1136	(ABC) transporter
FR741_05945	COG5002	protein histidine kinase activity
FR741_05945	COG3850	Histidine kinase
FR741_05950	COG0745	RESPONSE REGULATOR receiver
FR741_05960	COG0840	transmembrane signaling receptor activity
FR741_05975	COG1032	radical SAM domain protein
FR741_05980	COG5001	Diguanylate cyclase
FR741_05995	COG0583	DNA-binding transcription factor activity
FR741_06000	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FR741_06010	COG2350	Protein conserved in bacteria
FR741_06020	COG2917	probably involved in intracellular septation
FR741_06040	COG1301	dicarboxylic acid transport
FR741_06050	COG0318	PFAM AMP-dependent synthetase and ligase
FR741_06055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR741_06060	COG0159	tryptophan synthase activity
FR741_06070	COG0134	indole-3-glycerol-phosphate synthase activity
FR741_06070	COG0135	phosphoribosylanthranilate isomerase activity
FR741_06080	COG0512	Glutamine amidotransferase of anthranilate synthase
FR741_06085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FR741_06095	COG0613	PHP domain protein
FR741_06100	COG0009	L-threonylcarbamoyladenylate synthase
FR741_06110	COG1187	pseudouridine synthase activity
FR741_06130	COG0417	DNA replication proofreading
FR741_06135	COG2197	response regulator
FR741_06140	COG0322	excinuclease ABC activity
FR741_06180	COG0019	diaminopimelate decarboxylase activity
FR741_06210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FR741_06215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FR741_06235	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FR741_06245	COG0437	4 iron, 4 sulfur cluster binding
FR741_06250	COG3301	Polysulphide reductase, NrfD
FR741_06255	COG1138	Cytochrome C-type biogenesis protein
FR741_06265	COG4235	cytochrome complex assembly
FR741_06265	COG3088	subunit of a heme lyase
FR741_06275	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FR741_06300	COG2989	Protein conserved in bacteria
FR741_06305	COG3108	Peptidase M15
FR741_06310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FR741_06325	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FR741_06355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR741_06360	COG0840	transmembrane signaling receptor activity
FR741_06380	COG1448	Aminotransferase
FR741_06395	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR741_06405	COG0017	Asparaginyl-tRNA synthetase
FR741_06410	COG0840	transmembrane signaling receptor activity
FR741_06415	COG0720	synthase
FR741_06425	COG2200	EAL domain
FR741_06430	COG1760	l-serine dehydratase
FR741_06435	COG0814	amino acid
FR741_06440	COG0494	nUDIX hydrolase
FR741_06450	COG2205	protein histidine kinase activity
FR741_06450	COG0784	Response regulator, receiver
FR741_06455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FR741_06475	COG3106	COG3106 Predicted ATPase
FR741_06480	COG3768	UPF0283 membrane protein
FR741_06490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR741_06560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FR741_06560	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FR741_06640	COG0582	viral genome integration into host DNA
FR741_07015	COG0307	riboflavin synthase, alpha
FR741_07070	COG1683	Conserved Protein
FR741_07290	COG1619	proteins homologs of microcin C7 resistance protein MccF
FR741_07330	COG0346	lactoylglutathione lyase activity
FR741_07385	COG0456	acetyltransferase
FR741_07385	COG0454	-acetyltransferase
FR741_07410	COG0456	acetyltransferase
FR741_07485	COG5507	3-demethylubiquinone-9 3-methyltransferase
FR741_07495	COG1280	lysine exporter protein (LysE YggA)
FR741_07525	COG0583	DNA-binding transcription factor activity
FR741_07535	COG1566	PFAM secretion protein HlyD family protein
FR741_07550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR741_07565	COG3290	protein histidine kinase activity
FR741_07570	COG4565	transcriptional regulatory protein
FR741_07585	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FR741_07590	COG0363	glucosamine-6-phosphate deaminase activity
FR741_07595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FR741_07610	COG3284	Transcriptional regulator
FR741_07615	COG1012	belongs to the aldehyde dehydrogenase family
FR741_07685	COG4669	(LipO)protein
FR741_07705	COG3177	Filamentation induced by cAMP protein fic
FR741_07735	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_07760	COG4792	protein secretion
FR741_07765	COG4791	protein targeting
FR741_07770	COG4794	Type iii secretion
FR741_07775	COG4790	Type iii secretion
FR741_07845	COG0457	Tetratricopeptide repeat
FR741_07860	COG2358	TRAP transporter, solute receptor (TAXI family
FR741_07865	COG0730	response to heat
FR741_07900	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FR741_07905	COG0372	Belongs to the citrate synthase family
FR741_07915	COG2828	Protein conserved in bacteria
FR741_07940	COG0561	phosphatase activity
FR741_07945	COG0602	queuosine metabolic process
FR741_07950	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FR741_07955	COG3706	GGDEF domain
FR741_08005	COG1254	Belongs to the acylphosphatase family
FR741_08010	COG2920	part of a sulfur-relay system
FR741_08020	COG0670	Belongs to the BI1 family
FR741_08025	COG1126	abc transporter atp-binding protein
FR741_08030	COG0765	amino acid transport
FR741_08035	COG4597	amino acid ABC transporter
FR741_08040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR741_08055	COG1666	GTP binding
FR741_08060	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR741_08085	COG3008	intermembrane lipid transfer
FR741_08090	COG2995	paraquat-inducible protein a
FR741_08095	COG1132	(ABC) transporter
FR741_08100	COG1956	GAF domain-containing protein
FR741_08105	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FR741_08120	COG0308	aminopeptidase N
FR741_08130	COG2902	Dehydrogenase
FR741_08135	COG0167	dihydroorotate dehydrogenase activity
FR741_08145	COG0116	Belongs to the methyltransferase superfamily
FR741_08145	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FR741_08170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FR741_08175	COG1067	ATP-dependent peptidase activity
FR741_08180	COG3120	sequence-specific DNA binding
FR741_08200	COG2205	protein histidine kinase activity
FR741_08200	COG0784	Response regulator, receiver
FR741_08215	COG3278	Belongs to the heme-copper respiratory oxidase family
FR741_08230	COG2010	Cytochrome c
FR741_08240	COG2217	Heavy metal translocating P-type atpase
FR741_08255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FR741_08260	COG0589	response to stress
FR741_08285	COG3842	ATPase activity
FR741_08295	COG1177	transmembrane transport
FR741_08305	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FR741_08310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FR741_08315	COG0004	ammonium transporteR
FR741_08320	COG4282	regulation of fungal-type cell wall biogenesis
FR741_08340	COG0437	4 iron, 4 sulfur cluster binding
FR741_08345	COG0243	molybdopterin cofactor binding
FR741_08345	COG3383	formate dehydrogenase (NAD+) activity
FR741_08355	COG3381	protein complex oligomerization
FR741_08375	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FR741_08380	COG0488	(ABC) transporter
FR741_08390	COG4191	Histidine kinase
FR741_08395	COG2204	response regulator
FR741_08410	COG3842	ATPase activity
FR741_08415	COG0746	molybdenum cofactor guanylyltransferase activity
FR741_08430	COG1940	carbohydrate kinase activity
FR741_08470	COG0791	NLP P60 protein
FR741_08480	COG3706	GGDEF domain
FR741_08490	COG3001	Fructosamine kinase
FR741_08500	COG0307	riboflavin synthase, alpha
FR741_08505	COG0534	Mate efflux family protein
FR741_08515	COG1793	dna ligase
FR741_08545	COG2204	response regulator
FR741_08550	COG0297	glycogen (starch) synthase activity
FR741_08555	COG0438	transferase activity, transferring glycosyl groups
FR741_08585	COG0438	transferase activity, transferring glycosyl groups
FR741_08590	COG1215	transferase activity, transferring glycosyl groups
FR741_08595	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FR741_08605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR741_08620	COG1643	Atp-dependent helicase
FR741_08625	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FR741_08670	COG0443	Heat shock 70 kDa protein
FR741_08675	COG0443	Heat shock 70 kDa protein
FR741_08695	COG4968	Prepilin-type N-terminal cleavage methylation domain
FR741_08700	COG1132	(ABC) transporter
FR741_08705	COG1132	(ABC) transporter
FR741_08715	COG4774	siderophore transport
FR741_08725	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FR741_08730	COG1120	ATPase activity
FR741_08745	COG0814	amino acid
FR741_08755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FR741_08765	COG0861	Integral membrane protein TerC family
FR741_08775	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FR741_08780	COG1328	CTP reductase activity
FR741_08795	COG3300	MHYT domain
FR741_08795	COG5001	Diguanylate cyclase
FR741_08805	COG4191	Histidine kinase
FR741_08810	COG0471	metal ion transport
FR741_08835	COG4702	Belongs to the UPF0303 family
FR741_08840	COG0673	inositol 2-dehydrogenase activity
FR741_08845	COG1349	DNA-binding transcription factor activity
FR741_08860	COG0641	radical SAM
FR741_08875	COG3119	arylsulfatase activity
FR741_08880	COG0527	aspartate kinase activity
FR741_08885	COG0662	Cupin 2, conserved barrel domain protein
FR741_08890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FR741_08895	COG0456	acetyltransferase
FR741_08900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR741_08920	COG4176	ABC-type proline glycine betaine transport system permease component
FR741_08925	COG2113	Glycine betaine
FR741_08935	COG1022	Amp-dependent synthetase and ligase
FR741_08945	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_08955	COG0745	RESPONSE REGULATOR receiver
FR741_08960	COG0642	Histidine kinase
FR741_08965	COG1368	sulfuric ester hydrolase activity
FR741_08995	COG1115	amino acid carrier protein
FR741_09005	COG1280	lysine exporter protein (LysE YggA)
FR741_09010	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FR741_09015	COG1560	Kdo2-lipid A biosynthetic process
FR741_09020	COG0531	amino acid
FR741_09035	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FR741_09040	COG3063	Type IV pilus biogenesis stability protein PilW
FR741_09070	COG0110	maltose O-acetyltransferase activity
FR741_09085	COG2315	Protein conserved in bacteria
FR741_09090	COG1846	Transcriptional regulator
FR741_09100	COG2200	EAL domain
FR741_09135	COG0625	glutathione transferase activity
FR741_09145	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FR741_09155	COG2195	Cleaves the N-terminal amino acid of tripeptides
FR741_09165	COG0601	transmembrane transport
FR741_09170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR741_09190	COG3291	Pkd domain containing protein
FR741_09205	COG1177	transmembrane transport
FR741_09215	COG3842	ATPase activity
FR741_09220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FR741_09225	COG2423	ornithine cyclodeaminase activity
FR741_09240	COG3938	Belongs to the proline racemase family
FR741_09270	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FR741_09275	COG1451	nucleotide metabolic process
FR741_09285	COG0583	DNA-binding transcription factor activity
FR741_09305	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FR741_09310	COG4139	cobalamin transport
FR741_09315	COG2988	succinylglutamate desuccinylase activity
FR741_09335	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FR741_09340	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FR741_09345	COG0702	epimerase
FR741_09355	COG2925	Exonuclease
FR741_09360	COG1380	Effector of murein hydrolase LrgA
FR741_09365	COG1346	cytolysis
FR741_09370	COG0295	cytidine deaminase activity
FR741_09375	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FR741_09380	COG0500	methyltransferase
FR741_09390	COG0776	regulation of translation
FR741_09400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FR741_09400	COG0072	phenylalanine-tRNA ligase activity
FR741_09405	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FR741_09435	COG0393	Putative heavy-metal-binding
FR741_09445	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FR741_09455	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FR741_09470	COG2188	Transcriptional regulator
FR741_09475	COG1228	amidohydrolase
FR741_09480	COG0010	Belongs to the arginase family
FR741_09485	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FR741_09490	COG2986	histidine ammonia-lyase
FR741_09505	COG0247	lactate metabolic process
FR741_09505	COG0277	FAD linked oxidase domain protein
FR741_09540	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FR741_09555	COG1643	Atp-dependent helicase
FR741_09560	COG0281	malic enzyme
FR741_09565	COG2949	membrane
FR741_09570	COG0471	metal ion transport
FR741_09595	COG0492	ferredoxin-NADP+ reductase activity
FR741_09600	COG4988	ABC transporter
FR741_09605	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FR741_09615	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FR741_09625	COG4191	Histidine kinase
FR741_09625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR741_09640	COG3070	regulator of competence-specific genes
FR741_09655	COG2431	L-lysine efflux transmembrane transporter activity
FR741_09665	COG0076	glutamate decarboxylase activity
FR741_09670	COG1737	Transcriptional regulator
FR741_09685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FR741_09690	COG3273	potassium ion transport
FR741_09690	COG2985	domain, Protein
FR741_09695	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FR741_09700	COG1960	acyl-CoA dehydrogenase activity
FR741_09710	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FR741_09730	COG0534	Mate efflux family protein
FR741_09735	COG0702	epimerase
FR741_09740	COG3005	denitrification pathway
FR741_09770	COG2814	Major facilitator Superfamily
FR741_09780	COG1187	pseudouridine synthase activity
FR741_09785	COG1061	Type III restriction enzyme res subunit
FR741_09795	COG0745	RESPONSE REGULATOR receiver
FR741_09800	COG2205	protein histidine kinase activity
FR741_09810	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FR741_09830	COG3313	Fe-S protein
FR741_09840	COG4134	Bacterial extracellular solute-binding protein
FR741_09845	COG4135	transport system, permease component
FR741_09850	COG4136	ATPase activity
FR741_09855	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FR741_09870	COG3604	Transcriptional regulator
FR741_09875	COG1151	hydroxylamine reductase activity
FR741_09880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FR741_09890	COG0564	pseudouridine synthase activity
FR741_09895	COG0733	neurotransmitter:sodium symporter activity
FR741_09905	COG0626	cystathionine gamma-synthase activity
FR741_09910	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FR741_09915	COG5380	lipid catabolic process
FR741_09920	COG2818	Glycosylase
FR741_09940	COG1983	PspC domain protein
FR741_09950	COG1842	Phage shock protein A
FR741_09955	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FR741_09970	COG4171	peptide transport system, permease
FR741_09980	COG4172	Belongs to the ABC transporter superfamily
FR741_09990	COG1227	inorganic diphosphatase activity
FR741_10005	COG0243	molybdopterin cofactor binding
FR741_10010	COG3005	denitrification pathway
FR741_10015	COG4459	periplasmic nitrate reductase
FR741_10020	COG0390	transport system, permease component
FR741_10030	COG2116	formate transmembrane transporter activity
FR741_10055	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FR741_10060	COG1435	thymidine kinase activity
FR741_10065	COG0215	cysteine-tRNA ligase activity
FR741_10070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FR741_10075	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FR741_10080	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FR741_10085	COG3012	SEC-C Motif Domain Protein
FR741_10090	COG0140	phosphoribosyl-ATP diphosphatase activity
FR741_10090	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FR741_10105	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FR741_10110	COG0131	Imidazoleglycerol-phosphate dehydratase
FR741_10110	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FR741_10115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FR741_10120	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FR741_10125	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FR741_10135	COG1757	Na H antiporter
FR741_10145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR741_10155	COG0482	sulfurtransferase activity
FR741_10160	COG2915	High frequency lysogenization protein hflD homolog
FR741_10165	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FR741_10175	COG2268	Band 7 protein
FR741_10185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FR741_10200	COG0300	oxidoreductase activity
FR741_10220	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FR741_10225	COG1073	alpha beta
FR741_10225	COG2226	methyltransferase
FR741_10245	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FR741_10260	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FR741_10265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FR741_10270	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FR741_10275	COG1674	ftsk spoiiie
FR741_10285	COG0686	Belongs to the AlaDH PNT family
FR741_10295	COG0583	DNA-binding transcription factor activity
FR741_10310	COG0840	transmembrane signaling receptor activity
FR741_10320	COG3568	Endonuclease Exonuclease Phosphatase
FR741_10345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR741_10350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR741_10355	COG0840	transmembrane signaling receptor activity
FR741_10370	COG0784	Response regulator, receiver
FR741_10370	COG5002	protein histidine kinase activity
FR741_10380	COG0754	glutathionylspermidine amidase activity
FR741_10390	COG3766	membrane
FR741_10400	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FR741_10405	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FR741_10410	COG2885	chlorophyll binding
FR741_10415	COG0823	Involved in the tonB-independent uptake of proteins
FR741_10430	COG0811	peptide transport
FR741_10435	COG0824	Thioesterase
FR741_10445	COG4890	Cyd operon protein YbgT
FR741_10450	COG1294	oxidase, subunit
FR741_10455	COG1271	oxidase subunit
FR741_10460	COG2255	four-way junction helicase activity
FR741_10465	COG0632	four-way junction helicase activity
FR741_10470	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FR741_10475	COG0217	transcriptional regulatory protein
FR741_10485	COG1801	Protein of unknown function DUF72
FR741_10495	COG0500	methyltransferase
FR741_10505	COG4067	protein conserved in archaea
FR741_10505	COG0189	ligase activity
FR741_10525	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FR741_10530	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FR741_10535	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FR741_10540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FR741_10545	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FR741_10550	COG0745	RESPONSE REGULATOR receiver
FR741_10555	COG3381	protein complex oligomerization
FR741_10560	COG1609	Transcriptional regulator
FR741_10565	COG3070	regulator of competence-specific genes
FR741_10585	COG0297	glycogen (starch) synthase activity
FR741_10590	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FR741_10595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FR741_10615	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FR741_10620	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FR741_10625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FR741_10630	COG0542	response to heat
FR741_10635	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FR741_10640	COG1278	Cold shock
FR741_10650	COG1187	pseudouridine synthase activity
FR741_10655	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FR741_10660	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR741_10665	COG1199	ATP-dependent helicase activity
FR741_10670	COG0730	response to heat
FR741_10675	COG3923	Primosomal replication protein n
FR741_10685	COG0708	Exodeoxyribonuclease III
FR741_10730	COG1882	Formate acetyltransferase
FR741_10740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FR741_10750	COG3013	Belongs to the UPF0304 family
FR741_10760	COG2766	serine protein kinase
FR741_10765	COG2718	Belongs to the UPF0229 family
FR741_10770	COG2719	SpoVR family
FR741_10790	COG1132	(ABC) transporter
FR741_10795	COG0658	competence protein
FR741_10795	COG2333	competence protein COMEC
FR741_10805	COG4591	ABC-type transport system involved in lipoprotein release permease component
FR741_10810	COG1136	(ABC) transporter
FR741_10815	COG4591	ABC-type transport system involved in lipoprotein release permease component
FR741_10825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FR741_10840	COG1252	NADH dehydrogenase
FR741_10845	COG3150	esterase
FR741_10870	COG0537	adenosine 5'-monophosphoramidase activity
FR741_10895	COG0516	GMP reductase activity
FR741_10895	COG0517	IMP dehydrogenase activity
FR741_10900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR741_10930	COG1946	Acyl-CoA thioesterase
FR741_10940	COG1522	sequence-specific DNA binding
FR741_10965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR741_10970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR741_11015	COG2814	Major facilitator Superfamily
FR741_11020	COG2855	membrane
FR741_11040	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FR741_11045	COG0596	Alpha beta hydrolase
FR741_11050	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FR741_11055	COG1169	isochorismate synthase
FR741_11060	COG0436	Aminotransferase
FR741_11065	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FR741_11070	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FR741_11085	COG1555	photosystem II stabilization
FR741_11090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR741_11095	COG0776	regulation of translation
FR741_11100	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FR741_11105	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FR741_11115	COG0544	peptidyl-prolyl cis-trans isomerase activity
FR741_11140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FR741_11145	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FR741_11150	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FR741_11155	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FR741_11170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FR741_11175	COG0569	domain protein
FR741_11180	COG0513	Belongs to the DEAD box helicase family
FR741_11185	COG1253	flavin adenine dinucleotide binding
FR741_11220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FR741_11225	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FR741_11235	COG0318	PFAM AMP-dependent synthetase and ligase
FR741_11240	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FR741_11245	COG1216	Glycosyl transferase, family 2
FR741_11250	COG2986	histidine ammonia-lyase
FR741_11275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FR741_11285	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_11305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FR741_11310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR741_11320	COG2951	lytic endotransglycosylase activity
FR741_11325	COG3100	YcgL domain-containing protein
FR741_11330	COG0850	regulation of cytokinetic process
FR741_11335	COG2894	cell division
FR741_11340	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FR741_11345	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FR741_11350	COG0318	PFAM AMP-dependent synthetase and ligase
FR741_11355	COG2267	carboxylic ester hydrolase activity
FR741_11360	COG3065	identical protein binding
FR741_11370	COG1214	PFAM Peptidase M22, glycoprotease
FR741_11375	COG1199	ATP-dependent helicase activity
FR741_11380	COG0788	formyltetrahydrofolate deformylase activity
FR741_11385	COG3102	Protein conserved in bacteria
FR741_11395	COG0018	arginyl-trna synthetase
FR741_11415	COG1918	ferrous iron import across plasma membrane
FR741_11425	COG4977	sequence-specific DNA binding
FR741_11430	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FR741_11435	COG1121	(ABC) transporter
FR741_11440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR741_11455	COG0508	dehydrogenase complex catalyzes the overall conversion of
FR741_11460	COG0567	Dehydrogenase, E1 component
FR741_11465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FR741_11470	COG1053	succinate dehydrogenase
FR741_11475	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FR741_11490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FR741_11500	COG0033	Phosphoglucomutase
FR741_11505	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FR741_11510	COG0596	Alpha beta hydrolase
FR741_11520	COG0716	FMN binding
FR741_11530	COG0735	belongs to the Fur family
FR741_11535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FR741_11540	COG1263	PTS System
FR741_11540	COG2190	(PTS) system
FR741_11540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR741_11550	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FR741_11555	COG1940	carbohydrate kinase activity
FR741_11555	COG1846	Transcriptional regulator
FR741_11560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FR741_11560	COG4651	solute:proton antiporter activity
FR741_11565	COG0367	asparagine synthase
FR741_11570	COG0250	Participates in transcription elongation, termination and antitermination
FR741_11575	COG3104	oligopeptide transport
FR741_11580	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FR741_11590	COG0326	Molecular chaperone. Has ATPase activity
FR741_11595	COG3710	Transcriptional regulator
FR741_11615	COG0622	Phosphoesterase
FR741_11645	COG1090	epimerase
FR741_11650	COG0300	oxidoreductase activity
FR741_11660	COG3118	belongs to the thioredoxin family
FR741_11665	COG0330	HflC and HflK could
FR741_11690	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FR741_11695	COG3115	cell septum assembly
FR741_11700	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FR741_11705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FR741_11715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR741_11720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FR741_11725	COG2190	(PTS) system
FR741_11730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR741_11735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR741_11745	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR741_11750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR741_11760	COG1705	Flagellar rod assembly protein muramidase FlgJ
FR741_11760	COG3951	Flagellar rod assembly protein muramidase FlgJ
FR741_11765	COG1706	bacterial-type flagellum-dependent cell motility
FR741_11770	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FR741_11780	COG4787	bacterial-type flagellum-dependent cell motility
FR741_11785	COG1749	Flagellar hook protein flgE
FR741_11795	COG1558	bacterial-type flagellum-dependent cell motility
FR741_11800	COG1815	bacterial-type flagellum-dependent cell motility
FR741_11805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FR741_11810	COG0784	Response regulator, receiver
FR741_11810	COG0835	chemotaxis
FR741_11865	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FR741_11885	COG2608	mercury ion transmembrane transporter activity
FR741_11885	COG2217	Heavy metal translocating P-type atpase
FR741_11925	COG2840	Smr protein MutS2
FR741_11930	COG1187	pseudouridine synthase activity
FR741_11935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FR741_11940	COG0737	Belongs to the 5'-nucleotidase family
FR741_11945	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FR741_11950	COG2912	Transglutaminase-like superfamily
FR741_11955	COG3094	Invasion gene expression up-regulator, SirB
FR741_11960	COG2890	protein-(glutamine-N5) methyltransferase activity
FR741_11970	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FR741_11975	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FR741_11980	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FR741_11985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FR741_11990	COG0193	aminoacyl-tRNA hydrolase activity
FR741_11995	COG0012	GTP binding
FR741_12100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FR741_12110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FR741_12115	COG1702	phosphate starvation-inducible protein PhoH
FR741_12120	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FR741_12125	COG4535	Mg2 and Co2 transporter CorC
FR741_12130	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FR741_12135	COG2888	peptidyl-tyrosine sulfation
FR741_12140	COG0495	leucyl-tRNA aminoacylation
FR741_12145	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FR741_12150	COG1466	dna polymerase III delta subunit
FR741_12155	COG0799	negative regulation of ribosome biogenesis
FR741_12160	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FR741_12165	COG0768	penicillin binding
FR741_12170	COG0772	Belongs to the SEDS family
FR741_12175	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FR741_12180	COG1686	Belongs to the peptidase S11 family
FR741_12190	COG0321	lipoyl(octanoyl) transferase activity
FR741_12195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FR741_12200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FR741_12205	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FR741_12220	COG0366	Alpha amylase catalytic
FR741_12225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR741_12225	COG1263	PTS System
FR741_12235	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FR741_12240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FR741_12245	COG2011	ABC-type metal ion transport system permease component
FR741_12250	COG1464	Belongs to the NlpA lipoprotein family
FR741_12255	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FR741_12265	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FR741_12265	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FR741_12280	COG1611	Belongs to the LOG family
FR741_12285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FR741_12295	COG2363	Small membrane protein
FR741_12305	COG0583	DNA-binding transcription factor activity
FR741_12310	COG0301	tRNA thio-modification
FR741_12310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR741_12320	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FR741_12325	COG1722	exodeoxyribonuclease VII activity
FR741_12330	COG0142	geranyltranstransferase activity
FR741_12335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FR741_12340	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FR741_12345	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FR741_12355	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FR741_12370	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR741_12370	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR741_12375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FR741_12380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FR741_12385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FR741_12400	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FR741_12405	COG2252	PERMEase
FR741_12410	COG2195	Cleaves the N-terminal amino acid of tripeptides
FR741_12425	COG1629	transport
FR741_12440	COG0047	phosphoribosylformylglycinamidine synthase activity
FR741_12440	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FR741_12445	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FR741_12460	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FR741_12485	COG4969	Belongs to the N-Me-Phe pilin family
FR741_12495	COG0484	heat shock protein binding
FR741_12505	COG1301	dicarboxylic acid transport
FR741_12510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FR741_12515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FR741_12525	COG0497	DNA recombination
FR741_12530	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR741_12535	COG2914	Belongs to the UPF0125 (RnfH) family
FR741_12540	COG2867	negative regulation of translational initiation
FR741_12545	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FR741_12555	COG0582	viral genome integration into host DNA
FR741_12565	COG2207	Transcriptional regulator
FR741_12590	COG0583	DNA-binding transcription factor activity
FR741_12595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FR741_12595	COG3153	acetyltransferase
FR741_12615	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FR741_12620	COG2873	o-acetylhomoserine
FR741_12640	COG1115	amino acid carrier protein
FR741_12645	COG1584	GPR1 FUN34 yaaH family protein
FR741_12655	COG1757	Na H antiporter
FR741_12720	COG0582	viral genome integration into host DNA
FR741_12725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FR741_12725	COG0519	Catalyzes the synthesis of GMP from XMP
FR741_12730	COG0516	GMP reductase activity
FR741_12730	COG0517	IMP dehydrogenase activity
FR741_12750	COG1160	GTP binding
FR741_12755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR741_12760	COG2976	Protein conserved in bacteria
FR741_12765	COG0124	histidyl-tRNA synthetase
FR741_12770	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FR741_12790	COG0105	UTP biosynthetic process
FR741_12800	COG2975	iron-sulfur cluster assembly
FR741_12805	COG0633	Ferredoxin
FR741_12810	COG0443	Heat shock 70 kDa protein
FR741_12825	COG0822	iron-sulfur transferase activity
FR741_12830	COG1104	cysteine desulfurase activity
FR741_12840	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FR741_12845	COG0483	inositol monophosphate 1-phosphatase activity
FR741_12850	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR741_12855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR741_12860	COG1862	Preprotein translocase
FR741_12870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FR741_12885	COG0517	IMP dehydrogenase activity
FR741_12895	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FR741_12900	COG0583	DNA-binding transcription factor activity
FR741_12905	COG0450	alkyl hydroperoxide reductase
FR741_12910	COG3142	Participates in the control of copper homeostasis
FR741_12920	COG0704	Plays a role in the regulation of phosphate uptake
FR741_12925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FR741_12930	COG0581	inorganic phosphate transmembrane transporter activity
FR741_12935	COG0573	inorganic phosphate transmembrane transporter activity
FR741_12940	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FR741_12945	COG0248	Ppx GppA phosphatase
FR741_12955	COG5002	protein histidine kinase activity
FR741_12960	COG0745	RESPONSE REGULATOR receiver
FR741_12970	COG2974	May be involved in recombination
FR741_12980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR741_13040	COG0542	response to heat
FR741_13050	COG0564	pseudouridine synthase activity
FR741_13055	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR741_13060	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FR741_13065	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FR741_13070	COG1605	Chorismate mutase
FR741_13070	COG0077	Prephenate dehydratase
FR741_13075	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FR741_13080	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FR741_13090	COG0488	(ABC) transporter
FR741_13100	COG0739	heme binding
FR741_13100	COG1196	nuclear chromosome segregation
FR741_13100	COG0741	lytic transglycosylase activity
FR741_13105	COG0287	Prephenate dehydrogenase
FR741_13105	COG1605	Chorismate mutase
FR741_13110	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR741_13115	COG1472	Belongs to the glycosyl hydrolase 3 family
FR741_13120	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FR741_13140	COG1966	Carbon starvation protein
FR741_13145	COG3275	phosphorelay sensor kinase activity
FR741_13150	COG3279	Response regulator of the LytR AlgR family
FR741_13160	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FR741_13165	COG1047	Peptidyl-prolyl cis-trans
FR741_13170	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FR741_13180	COG0196	riboflavin kinase activity
FR741_13185	COG0728	peptidoglycan biosynthetic process
FR741_13190	COG0268	Binds directly to 16S ribosomal RNA
FR741_13195	COG0640	Transcriptional regulator
FR741_13200	COG0583	DNA-binding transcription factor activity
FR741_13205	COG1283	sodium-dependent phosphate transmembrane transporter activity
FR741_13215	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FR741_13225	COG0730	response to heat
FR741_13250	COG0667	Aldo Keto reductase
FR741_13260	COG2204	response regulator
FR741_13265	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FR741_13275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FR741_13280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR741_13285	COG4974	Belongs to the 'phage' integrase family
FR741_13290	COG0716	FMN binding
FR741_13300	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FR741_13305	COG0513	Belongs to the DEAD box helicase family
FR741_13310	COG3022	response to hydroperoxide
FR741_13315	COG1115	amino acid carrier protein
FR741_13330	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FR741_13340	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FR741_13345	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FR741_13355	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FR741_13360	COG0083	homoserine kinase activity
FR741_13380	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FR741_13395	COG0745	RESPONSE REGULATOR receiver
FR741_13405	COG5002	protein histidine kinase activity
FR741_13405	COG0784	Response regulator, receiver
FR741_13405	COG2198	Histidine kinase
FR741_13410	COG4251	negative regulation of phosphorylation
FR741_13410	COG3706	GGDEF domain
FR741_13410	COG2203	Gaf domain
FR741_13410	COG5001	Diguanylate cyclase
FR741_13415	COG1242	4 iron, 4 sulfur cluster binding
FR741_13420	COG0067	glutamate synthase
FR741_13420	COG0070	glutamate synthase
FR741_13420	COG0069	glutamate synthase activity
FR741_13430	COG0070	glutamate synthase
FR741_13430	COG0067	glutamate synthase
FR741_13430	COG0069	glutamate synthase activity
FR741_13435	COG0493	'glutamate synthase
FR741_13445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FR741_13460	COG2860	membrane
FR741_13465	COG0583	DNA-binding transcription factor activity
FR741_13470	COG0730	response to heat
FR741_13490	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FR741_13495	COG0505	Belongs to the CarA family
FR741_13505	COG0494	nUDIX hydrolase
FR741_13510	COG0653	protein targeting
FR741_13520	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FR741_13525	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FR741_13530	COG0849	cell division
FR741_13535	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FR741_13540	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FR741_13550	COG0772	Belongs to the SEDS family
FR741_13555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FR741_13560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FR741_13565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FR741_13570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FR741_13575	COG0768	penicillin binding
FR741_13580	COG3116	cell division
FR741_13595	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FR741_13610	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FR741_13615	COG2823	Periplasmic or secreted lipoprotein
FR741_13620	COG2969	positive regulation of protein catabolic process
FR741_13625	COG0625	glutathione transferase activity
FR741_13630	COG2857	Cytochrome c1
FR741_13635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FR741_13640	COG0723	plastoquinol--plastocyanin reductase activity
FR741_13645	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FR741_13650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FR741_13660	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FR741_13670	COG3105	Protein conserved in bacteria
FR741_13680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FR741_13685	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FR741_13695	COG3150	esterase
FR741_13705	COG3151	Protein conserved in bacteria
FR741_13710	COG0494	nUDIX hydrolase
FR741_13715	COG1538	Outer membrane efflux protein
FR741_13720	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FR741_13720	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FR741_13725	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FR741_13740	COG3025	triphosphatase activity
FR741_13745	COG1392	Phosphate transport regulator
FR741_13750	COG0306	phosphate transporter
FR741_13755	COG4991	sh3 domain protein
FR741_13760	COG0405	Gamma-glutamyltransferase
FR741_13770	COG3409	Peptidoglycan-binding domain 1 protein
FR741_13770	COG3267	Type II secretory pathway component ExeA
FR741_13775	COG0617	tRNA 3'-terminal CCA addition
FR741_13780	COG1968	undecaprenyl-diphosphatase activity
FR741_13785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FR741_13790	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FR741_13795	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FR741_13800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FR741_13805	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FR741_13810	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FR741_13815	COG1610	YqeY-like protein
FR741_13820	COG0358	DNA primase activity
FR741_13900	COG1484	DNA-dependent DNA replication
FR741_13940	COG0582	viral genome integration into host DNA
FR741_14055	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR741_14055	COG2213	PTS system mannitol-specific
FR741_14060	COG0246	Mannitol dehydrogenase
FR741_14065	COG3722	fumarate hydratase activity
FR741_14080	COG1461	Dihydroxyacetone kinase
FR741_14085	COG2376	Dihydroxyacetone kinase
FR741_14095	COG5002	protein histidine kinase activity
FR741_14110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FR741_14115	COG1349	DNA-binding transcription factor activity
FR741_14120	COG0469	pyruvate kinase activity
FR741_14130	COG3706	GGDEF domain
FR741_14140	COG0028	Belongs to the TPP enzyme family
FR741_14145	COG1022	Amp-dependent synthetase and ligase
FR741_14150	COG0583	DNA-binding transcription factor activity
FR741_14175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FR741_14180	COG0473	3-isopropylmalate dehydrogenase activity
FR741_14200	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FR741_14205	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FR741_14210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR741_14215	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FR741_14220	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FR741_14225	COG2967	ApaG domain
FR741_14245	COG2966	Psort location CytoplasmicMembrane, score
FR741_14250	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FR741_14260	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FR741_14265	COG0142	geranyltranstransferase activity
FR741_14290	COG2358	TRAP transporter, solute receptor (TAXI family
FR741_14310	COG1902	pentaerythritol trinitrate reductase activity
FR741_14315	COG0583	DNA-binding transcription factor activity
FR741_14320	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FR741_14325	COG1178	ABC-type Fe3 transport system permease component
FR741_14330	COG4143	(ABC) transporter
FR741_14335	COG0163	prenyltransferase activity
FR741_14340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FR741_14350	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FR741_14355	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FR741_14365	COG2105	PFAM AIG2 family protein
FR741_14370	COG2911	Protein conserved in bacteria
FR741_14375	COG0729	surface antigen
FR741_14380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR741_14390	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FR741_14405	COG4181	ATPase activity
FR741_14425	COG0529	Catalyzes the synthesis of activated sulfate
FR741_14430	COG3273	potassium ion transport
FR741_14430	COG0471	metal ion transport
FR741_14435	COG2895	sulfate adenylyltransferase (ATP) activity
FR741_14440	COG0175	sulfate reduction
FR741_14445	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FR741_14445	COG1648	precorrin-2 dehydrogenase activity
FR741_14460	COG0513	Belongs to the DEAD box helicase family
FR741_14465	COG2153	protein acetylation
FR741_14475	COG0545	Peptidyl-prolyl cis-trans isomerase
FR741_14485	COG0203	ribosomal protein L17
FR741_14490	COG0202	RNA polymerase activity
FR741_14500	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FR741_14505	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FR741_14510	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FR741_14515	COG0201	protein transport
FR741_14525	COG1841	ribosomal large subunit assembly
FR741_14540	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FR741_14545	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FR741_14550	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FR741_14555	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FR741_14560	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FR741_14570	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FR741_14575	COG0255	Belongs to the universal ribosomal protein uL29 family
FR741_14585	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FR741_14590	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FR741_14595	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FR741_14600	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FR741_14610	COG0088	Forms part of the polypeptide exit tunnel
FR741_14615	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FR741_14625	COG0254	rRNA binding
FR741_14635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FR741_14640	COG1609	Transcriptional regulator
FR741_14650	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FR741_14655	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FR741_14660	COG1575	Belongs to the MenA family. Type 1 subfamily
FR741_14665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FR741_14680	COG1494	fructose-1,6-bisphosphatase
FR741_14710	COG0149	triose-phosphate isomerase activity
FR741_14730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FR741_14740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FR741_14745	COG0438	transferase activity, transferring glycosyl groups
FR741_14780	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FR741_14785	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FR741_14790	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FR741_14795	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FR741_14800	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FR741_14830	COG0517	IMP dehydrogenase activity
FR741_14830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FR741_14865	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FR741_14875	COG1560	Kdo2-lipid A biosynthetic process
FR741_14880	COG0859	PFAM glycosyl transferase family 9
FR741_14885	COG1519	Transferase
FR741_14895	COG1083	cytidylyl-transferase
FR741_14900	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FR741_14910	COG2089	acid synthase
FR741_14915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FR741_14920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FR741_14925	COG1086	Polysaccharide biosynthesis protein
FR741_14935	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FR741_14955	COG3642	lipopolysaccharide core region biosynthetic process
FR741_14960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FR741_14965	COG0859	PFAM glycosyl transferase family 9
FR741_14970	COG0463	Glycosyl transferase, family 2
FR741_15015	COG2003	Belongs to the UPF0758 family
FR741_15030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FR741_15035	COG1309	transcriptional regulator
FR741_15040	COG1560	Kdo2-lipid A biosynthetic process
FR741_15045	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FR741_15050	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FR741_15060	COG1561	YicC-like family, N-terminal region
FR741_15095	COG4608	Belongs to the ABC transporter superfamily
FR741_15100	COG0444	Belongs to the ABC transporter superfamily
FR741_15105	COG0747	negative chemotaxis
FR741_15110	COG4239	(ABC) transporter, permease
FR741_15115	COG4174	ABC transporter (Permease)
FR741_15140	COG0811	peptide transport
FR741_15145	COG0848	biopolymer transport protein
FR741_15160	COG0194	GDP metabolic process
FR741_15165	COG1758	RNA polymerase activity
FR741_15170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FR741_15175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FR741_15180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FR741_15185	COG2233	PERMEase
FR741_15190	COG2205	protein histidine kinase activity
FR741_15195	COG0745	RESPONSE REGULATOR receiver
FR741_15205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FR741_15215	COG2183	response to ionizing radiation
FR741_15225	COG0596	Alpha beta hydrolase
FR741_15230	COG1040	competence protein
FR741_15235	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FR741_15235	COG0316	Belongs to the HesB IscA family
FR741_15240	COG0494	nUDIX hydrolase
FR741_15245	COG1218	3'(2'),5'-bisphosphate nucleotidase
FR741_15255	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FR741_15260	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FR741_15265	COG3156	type II secretion system protein K
FR741_15270	COG4795	General secretion pathway protein
FR741_15275	COG2165	general secretion pathway protein
FR741_15280	COG2165	general secretion pathway protein
FR741_15285	COG2165	general secretion pathway protein
FR741_15290	COG1459	type II secretion system
FR741_15295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FR741_15305	COG3031	protein transport across the cell outer membrane
FR741_15310	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FR741_15315	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FR741_15320	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FR741_15330	COG0456	acetyltransferase
FR741_15335	COG1490	D-aminoacyl-tRNA deacylase activity
FR741_15340	COG1295	ribonuclease BN
FR741_15365	COG0174	glutamine synthetase
FR741_15375	COG3852	Histidine kinase
FR741_15380	COG2204	response regulator
FR741_15390	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FR741_15425	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FR741_15430	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FR741_15430	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FR741_15440	COG0456	acetyltransferase
FR741_15455	COG0084	hydrolase, TatD family'
FR741_15465	COG0805	protein transport
FR741_15470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FR741_15480	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FR741_15485	COG3165	ubiquinone biosynthetic process from chorismate
FR741_15490	COG2226	methyltransferase
FR741_15495	COG1322	Protein conserved in bacteria
FR741_15510	COG0628	permease
FR741_15540	COG1597	lipid kinase activity
FR741_15570	COG2081	HI0933 family
FR741_15580	COG1528	Iron-storage protein
FR741_15585	COG0589	response to stress
FR741_15600	COG0742	ribosomal rna small subunit methyltransferase
FR741_15605	COG5002	protein histidine kinase activity
FR741_15605	COG5001	Diguanylate cyclase
FR741_15610	COG1522	sequence-specific DNA binding
FR741_15625	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FR741_15630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FR741_15635	COG0583	DNA-binding transcription factor activity
FR741_15640	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FR741_15645	COG0800	Aldolase
FR741_15650	COG2610	gluconate transmembrane transporter activity
FR741_15655	COG3265	gluconokinase activity
FR741_15660	COG0129	dihydroxy-acid dehydratase activity
FR741_15675	COG0583	DNA-binding transcription factor activity
FR741_15680	COG1609	Transcriptional regulator
FR741_15720	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FR741_15730	COG4166	transmembrane transport
FR741_15790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR741_15795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR741_15800	COG2960	long-chain fatty acid transporting porin activity
FR741_15805	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FR741_15810	COG0583	DNA-binding transcription factor activity
FR741_15860	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FR741_15865	COG1739	Uncharacterized protein family UPF0029
FR741_15875	COG0183	Belongs to the thiolase family
FR741_15880	COG0604	alcohol dehydrogenase
FR741_15895	COG0425	Belongs to the sulfur carrier protein TusA family
FR741_15905	COG2119	membrane
FR741_15915	COG0751	glycine-tRNA ligase activity
FR741_15920	COG0366	Alpha amylase catalytic
FR741_15925	COG3977	Valine--pyruvate aminotransferase
FR741_15930	COG0071	Belongs to the small heat shock protein (HSP20) family
FR741_15945	COG0187	DNA topoisomerase II activity
FR741_15955	COG0592	DNA-directed DNA polymerase activity
FR741_15965	COG4608	Belongs to the ABC transporter superfamily
FR741_15970	COG0444	Belongs to the ABC transporter superfamily
FR741_15980	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FR741_15980	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FR741_16005	COG0772	Belongs to the SEDS family
FR741_16015	COG1136	(ABC) transporter
FR741_16035	COG3275	phosphorelay sensor kinase activity
FR741_16040	COG3279	Response regulator of the LytR AlgR family
FR741_16050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FR741_16070	COG0786	glutamate:sodium symporter activity
FR741_16080	COG1131	(ABC) transporter
FR741_16085	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR741_16090	COG0786	glutamate:sodium symporter activity
FR741_16100	COG0363	glucosamine-6-phosphate deaminase activity
FR741_16120	COG1741	Belongs to the pirin family
FR741_16125	COG2259	Doxx family
FR741_16135	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FR741_16140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FR741_16150	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FR741_16175	COG0596	Alpha beta hydrolase
FR741_16190	COG3123	guanosine phosphorylase activity
FR741_16210	COG0534	Mate efflux family protein
FR741_16215	COG0564	pseudouridine synthase activity
FR741_16230	COG0583	DNA-binding transcription factor activity
FR741_16235	COG0561	phosphatase activity
FR741_16245	COG2199	diguanylate cyclase activity
FR741_16260	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FR741_16265	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FR741_16270	COG0583	DNA-binding transcription factor activity
FR741_16285	COG1414	Transcriptional regulator
FR741_16290	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_16300	COG1917	Cupin 2, conserved barrel domain protein
FR741_16315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR741_16320	COG0800	Aldolase
FR741_16340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR741_16345	COG0823	Involved in the tonB-independent uptake of proteins
FR741_16350	COG2375	cellular response to nickel ion
FR741_16385	COG1357	PFAM Pentapeptide repeats (8 copies)
FR741_16390	COG3047	cAMP biosynthetic process
FR741_16420	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FR741_16420	COG3408	Glycogen debranching enzyme
FR741_16425	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FR741_16445	COG0583	DNA-binding transcription factor activity
FR741_16460	COG0546	phosphoglycolate phosphatase activity
FR741_16485	COG3835	regulator
FR741_16490	COG2610	gluconate transmembrane transporter activity
FR741_16495	COG1929	Belongs to the glycerate kinase type-1 family
FR741_16500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR741_16520	COG0456	acetyltransferase
FR741_16535	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_16540	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR741_16545	COG3005	denitrification pathway
FR741_16550	COG0243	molybdopterin cofactor binding
FR741_16560	COG0352	thiamine-phosphate diphosphorylase activity
FR741_16565	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FR741_16570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FR741_16575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR741_16580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR741_16585	COG1116	anion transmembrane transporter activity
FR741_16590	COG0351	phosphomethylpyrimidine kinase
FR741_16595	COG0312	modulator of DNA gyrase
FR741_16600	COG0312	modulator of DNA gyrase
FR741_16605	COG1901	pseudouridine methyltransferase
FR741_16665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FR741_16675	COG0584	glycerophosphoryl diester phosphodiesterase
FR741_16680	COG0039	L-malate dehydrogenase activity
FR741_16685	COG0745	RESPONSE REGULATOR receiver
FR741_16705	COG0811	peptide transport
FR741_16710	COG0811	peptide transport
FR741_16715	COG0848	biopolymer transport protein
FR741_16760	COG0803	Belongs to the bacterial solute-binding protein 9 family
FR741_16765	COG1121	(ABC) transporter
FR741_16770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FR741_16785	COG1770	oligopeptidase
FR741_16790	COG2814	Major facilitator Superfamily
FR741_16795	COG0010	Belongs to the arginase family
FR741_16800	COG1166	arginine decarboxylase activity
FR741_16810	COG0189	ligase activity
FR741_16810	COG4067	protein conserved in archaea
FR741_16815	COG0189	ligase activity
FR741_16825	COG0583	DNA-binding transcription factor activity
FR741_16860	COG4191	Histidine kinase
FR741_16865	COG2204	response regulator
FR741_16870	COG3706	GGDEF domain
FR741_16895	COG0579	oxidoreductase
FR741_16910	COG1294	oxidase, subunit
FR741_16915	COG1271	oxidase subunit
FR741_16925	COG3033	Beta-eliminating lyase
FR741_16945	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FR741_16960	COG3706	GGDEF domain
FR741_16975	COG3706	GGDEF domain
FR741_16980	COG0415	Belongs to the DNA photolyase family
FR741_16985	COG3046	protein related to deoxyribodipyrimidine photolyase
FR741_17000	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR741_17000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR741_17005	COG1765	OsmC-like protein
FR741_17010	COG0110	maltose O-acetyltransferase activity
FR741_17050	COG1011	Hydrolase
FR741_17065	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FR741_17075	COG2067	long-chain fatty acid transport protein
FR741_17080	COG3240	lipase activity
FR741_17110	COG1609	Transcriptional regulator
FR741_17115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR741_17130	COG1840	ABC-type Fe3 transport system, periplasmic component
FR741_17135	COG3842	ATPase activity
FR741_17160	COG2990	Protein conserved in bacteria
FR741_17170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FR741_17175	COG2866	Carboxypeptidase
FR741_17185	COG0583	DNA-binding transcription factor activity
FR741_17205	COG3104	oligopeptide transport
FR741_17210	COG1760	l-serine dehydratase
FR741_17230	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FR741_17235	COG0741	lytic transglycosylase activity
FR741_17255	COG1815	bacterial-type flagellum-dependent cell motility
FR741_17260	COG1558	bacterial-type flagellum-dependent cell motility
FR741_17265	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FR741_17270	COG1749	Flagellar hook protein flgE
FR741_17275	COG4787	bacterial-type flagellum-dependent cell motility
FR741_17280	COG4786	Flagellar basal body rod
FR741_17285	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FR741_17290	COG1706	bacterial-type flagellum-dependent cell motility
FR741_17300	COG1256	bacterial-type flagellum assembly
FR741_17300	COG4786	Flagellar basal body rod
FR741_17305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR741_17325	COG1304	FMN binding
FR741_17340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FR741_17345	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FR741_17350	COG0459	protein refolding
FR741_17380	COG1309	transcriptional regulator
FR741_17385	COG2207	Transcriptional regulator
FR741_17390	COG4303	Ethanolamine ammonia lyase large subunit
FR741_17395	COG4302	ethanolamine ammonia-lyase activity
FR741_17400	COG0531	amino acid
FR741_17405	COG2070	2-Nitropropane dioxygenase
FR741_17410	COG3537	Alpha-1,2-mannosidase
FR741_17415	COG3537	Alpha-1,2-mannosidase
FR741_17425	COG3537	Alpha-1,2-mannosidase
FR741_17430	COG3537	Alpha-1,2-mannosidase
FR741_17435	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR741_17445	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR741_17445	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FR741_17450	COG0346	lactoylglutathione lyase activity
FR741_17455	COG1349	DNA-binding transcription factor activity
FR741_17465	COG1335	isochorismatase
FR741_17475	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FR741_17500	COG0583	DNA-binding transcription factor activity
FR741_17515	COG3713	MltA-interacting MipA family protein
FR741_17520	COG3015	lipoprotein NlpE involved in copper resistance
FR741_17525	COG3448	diguanylate cyclase activity
FR741_17525	COG4175	Glycine betaine
FR741_17530	COG4176	ABC-type proline glycine betaine transport system permease component
FR741_17540	COG1342	Belongs to the UPF0251 family
FR741_17575	COG4948	Mandelate Racemase Muconate Lactonizing
FR741_17585	COG0583	DNA-binding transcription factor activity
FR741_17630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FR741_17660	COG3842	ATPase activity
FR741_17690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR741_17715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR741_17730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FR741_17735	COG2197	response regulator
FR741_17750	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FR741_17755	COG0252	asparaginase activity
FR741_17765	COG0583	DNA-binding transcription factor activity
FR741_17780	COG3122	Protein conserved in bacteria
FR741_17790	COG2423	ornithine cyclodeaminase activity
FR741_17795	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FR741_17800	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FR741_17805	COG1012	belongs to the aldehyde dehydrogenase family
FR741_17810	COG1522	sequence-specific DNA binding
FR741_17815	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FR741_17820	COG3608	succinylglutamate desuccinylase aspartoacylase
FR741_17825	COG0006	proline dipeptidase activity
FR741_17830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR741_17835	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FR741_17840	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FR741_17850	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_17860	COG1063	alcohol dehydrogenase
FR741_17865	COG1902	pentaerythritol trinitrate reductase activity
FR741_17880	COG0583	DNA-binding transcription factor activity
FR741_17890	COG0513	Belongs to the DEAD box helicase family
FR741_17930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR741_17935	COG2207	Transcriptional regulator
FR741_17935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FR741_17955	COG3746	phosphate-selective porin O and P
FR741_17970	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_18000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR741_18000	COG1263	PTS System
FR741_18005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR741_18010	COG1621	beta-fructofuranosidase activity
FR741_18020	COG0625	glutathione transferase activity
FR741_18030	COG1686	Belongs to the peptidase S11 family
FR741_18045	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FR741_18060	COG1278	Cold shock
FR741_18065	COG1741	Belongs to the pirin family
FR741_18070	COG4667	esterase of the alpha-beta hydrolase superfamily
FR741_18090	COG2194	sulfuric ester hydrolase activity
FR741_18095	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FR741_18105	COG2205	protein histidine kinase activity
FR741_18110	COG0745	RESPONSE REGULATOR receiver
FR741_18125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FR741_18145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FR741_18155	COG2814	Major facilitator Superfamily
FR741_18170	COG1418	mRNA catabolic process
FR741_18175	COG0402	S-adenosylhomocysteine deaminase activity
FR741_18180	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FR741_18185	COG2239	Acts as a magnesium transporter
FR741_18190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FR741_18195	COG1566	PFAM secretion protein HlyD family protein
FR741_18220	COG0745	RESPONSE REGULATOR receiver
FR741_18225	COG2205	protein histidine kinase activity
FR741_18240	COG0531	amino acid
FR741_18255	COG0583	DNA-binding transcription factor activity
FR741_18275	COG2205	protein histidine kinase activity
FR741_18275	COG0784	Response regulator, receiver
FR741_18275	COG5002	protein histidine kinase activity
FR741_18280	COG0534	Mate efflux family protein
FR741_18295	COG3132	Protein of unknown function, DUF480
FR741_18300	COG2827	Endonuclease containing a URI domain
FR741_18310	COG1879	ABC-type sugar transport system periplasmic component
FR741_18315	COG2205	protein histidine kinase activity
FR741_18315	COG0784	Response regulator, receiver
FR741_18375	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR741_18380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FR741_18390	COG1280	lysine exporter protein (LysE YggA)
FR741_18405	COG0183	Belongs to the thiolase family
FR741_18415	COG3243	poly(R)-hydroxyalkanoic acid synthase
FR741_18425	COG3005	denitrification pathway
FR741_18435	COG0243	molybdopterin cofactor binding
FR741_18445	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FR741_18450	COG3850	Histidine kinase
FR741_18455	COG2197	response regulator
FR741_18470	COG2195	Cleaves the N-terminal amino acid of tripeptides
FR741_18490	COG0840	transmembrane signaling receptor activity
FR741_18500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR741_18515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FR741_18520	COG2814	Major facilitator Superfamily
FR741_18525	COG0840	transmembrane signaling receptor activity
FR741_18530	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FR741_18535	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FR741_18565	COG2897	thiosulfate sulfurtransferase activity
FR741_18585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FR741_18600	COG1914	H( )-stimulated, divalent metal cation uptake system
FR741_18610	COG0038	chloride channel
FR741_18625	COG4989	oxidoreductase activity
FR741_18640	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FR741_18640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FR741_18690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR741_18705	COG1013	pyruvate-flavodoxin oxidoreductase activity
FR741_18710	COG0674	pyruvate-flavodoxin oxidoreductase activity
FR741_18710	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FR741_18715	COG0583	DNA-binding transcription factor activity
FR741_18720	COG0739	heme binding
FR741_18760	COG3501	Rhs element vgr protein
FR741_18785	COG0515	serine threonine protein kinase
FR741_18820	COG1522	sequence-specific DNA binding
FR741_18865	COG3179	chitinase
FR741_18890	COG2814	Major facilitator Superfamily
FR741_18900	COG0583	DNA-binding transcription factor activity
FR741_18905	COG4221	oxidoreductase activity
FR741_18910	COG0589	response to stress
FR741_18920	COG2111	Na H antiporter
FR741_18920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FR741_18940	COG2212	antiporter activity
FR741_18945	COG1320	monovalent cation:proton antiporter activity
FR741_18950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FR741_19015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR741_19020	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_19030	COG3527	Alpha-acetolactate decarboxylase
FR741_19040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR741_19055	COG1294	oxidase, subunit
FR741_19060	COG1271	oxidase subunit
FR741_19065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FR741_19070	COG0110	maltose O-acetyltransferase activity
FR741_19085	COG4999	Histidine kinase
FR741_19085	COG3437	response regulator, receiver
FR741_19085	COG2205	protein histidine kinase activity
FR741_19085	COG3850	Histidine kinase
FR741_19095	COG4770	biotin carboxylase activity
FR741_19105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FR741_19110	COG1960	acyl-CoA dehydrogenase activity
FR741_19120	COG0183	Belongs to the thiolase family
FR741_19130	COG1960	acyl-CoA dehydrogenase activity
FR741_19135	COG1024	Enoyl-CoA hydratase
FR741_19150	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_19160	COG1309	transcriptional regulator
FR741_19165	COG1012	belongs to the aldehyde dehydrogenase family
FR741_19180	COG4176	ABC-type proline glycine betaine transport system permease component
FR741_19185	COG4175	Glycine betaine
FR741_19185	COG0517	IMP dehydrogenase activity
FR741_19200	COG0330	HflC and HflK could
FR741_19210	COG3300	MHYT domain
FR741_19210	COG5001	Diguanylate cyclase
FR741_19220	COG0784	Response regulator, receiver
FR741_19220	COG2205	protein histidine kinase activity
FR741_19230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FR741_19280	COG5001	Diguanylate cyclase
FR741_19285	COG1869	D-ribose catabolic process
FR741_19290	COG1129	ABC transporter
FR741_19295	COG1172	Belongs to the binding-protein-dependent transport system permease family
FR741_19300	COG1879	ABC-type sugar transport system periplasmic component
FR741_19305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR741_19310	COG1609	Transcriptional regulator
FR741_19325	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FR741_19335	COG4607	ABC-type enterochelin transport system periplasmic component
FR741_19340	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR741_19345	COG4605	iron ion homeostasis
FR741_19350	COG4604	ABC transporter, ATP-binding protein
FR741_19355	COG0789	Transcriptional regulator
FR741_19360	COG2207	Transcriptional regulator
FR741_19365	COG1629	transport
FR741_19365	COG4771	TonB-dependent receptor
FR741_19395	COG1289	transmembrane transporter activity
FR741_19400	COG0210	DNA helicase
FR741_19405	COG1803	Methylglyoxal synthase
FR741_19410	COG1879	ABC-type sugar transport system periplasmic component
FR741_19415	COG0784	Response regulator, receiver
FR741_19415	COG2205	protein histidine kinase activity
FR741_19415	COG2198	Histidine kinase
FR741_19435	COG3119	arylsulfatase activity
FR741_19445	COG3119	arylsulfatase activity
FR741_19450	COG0641	radical SAM
FR741_19455	COG0714	Associated with various cellular activities
FR741_19485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR741_19485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FR741_19490	COG0583	DNA-binding transcription factor activity
FR741_19495	COG1597	lipid kinase activity
FR741_19500	COG3111	PFAM Bacterial OB fold (BOF) protein
FR741_19515	COG2223	nitrite transmembrane transporter activity
FR741_19525	COG0501	Belongs to the peptidase M48B family
FR741_19530	COG1704	LemA family
FR741_19535	COG3069	C4-dicarboxylate transmembrane transporter activity
FR741_19545	COG0456	acetyltransferase
FR741_19545	COG1214	PFAM Peptidase M22, glycoprotease
FR741_19565	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FR741_19575	COG3706	GGDEF domain
FR741_19585	COG2197	response regulator
FR741_19590	COG0784	Response regulator, receiver
FR741_19590	COG0835	chemotaxis
FR741_19605	COG2962	Rard protein
FR741_19670	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FR741_19675	COG5642	Protein of unknown function (DUF2384)
FR741_19685	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FR741_19685	COG2755	lipolytic protein G-D-S-L family
FR741_19695	COG1902	pentaerythritol trinitrate reductase activity
FR741_19700	COG0346	lactoylglutathione lyase activity
FR741_19720	COG2239	Acts as a magnesium transporter
FR741_19750	COG0242	peptide deformylase activity
FR741_19790	COG2176	DNA-directed DNA polymerase activity
FR741_19815	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FR741_19825	COG0346	lactoylglutathione lyase activity
FR741_19830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FR741_19830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FR741_19835	COG0509	glycine decarboxylation via glycine cleavage system
FR741_19840	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FR741_19850	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FR741_19860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR741_19880	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FR741_19880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR741_19880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR741_19885	COG1105	Belongs to the carbohydrate kinase PfkB family
FR741_19890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR741_19890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR741_19895	COG1609	Transcriptional regulator
FR741_19910	COG2199	diguanylate cyclase activity
FR741_19910	COG2200	EAL domain
FR741_19910	COG2203	Gaf domain
FR741_19915	COG0765	amino acid transport
FR741_19920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR741_19925	COG0765	amino acid transport
FR741_19930	COG1126	abc transporter atp-binding protein
FR741_19940	COG1979	alcohol dehydrogenase
FR741_19945	COG2207	Transcriptional regulator
FR741_19960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FR741_19965	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FR741_19970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FR741_19985	COG0546	phosphoglycolate phosphatase activity
FR741_19995	COG0840	transmembrane signaling receptor activity
FR741_20010	COG0513	Belongs to the DEAD box helicase family
FR741_20015	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FR741_20030	COG3038	cytochrome b561
FR741_20035	COG2353	YceI-like domain
FR741_20040	COG2116	formate transmembrane transporter activity
FR741_20050	COG0583	DNA-binding transcription factor activity
FR741_20060	COG3593	DNA synthesis involved in DNA repair
FR741_20065	COG0737	Belongs to the 5'-nucleotidase family
FR741_20090	COG2267	carboxylic ester hydrolase activity
FR741_20095	COG2067	long-chain fatty acid transport protein
FR741_20110	COG2050	protein possibly involved in aromatic compounds catabolism
FR741_20120	COG4533	DNA binding
FR741_20155	COG5001	Diguanylate cyclase
FR741_20155	COG1716	ATPase activity
FR741_20160	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FR741_20170	COG4181	ATPase activity
FR741_20175	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FR741_20185	COG1984	allophanate hydrolase subunit 2
FR741_20190	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FR741_20195	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FR741_20200	COG5002	protein histidine kinase activity
FR741_20200	COG5001	Diguanylate cyclase
FR741_20200	COG3447	MASE1 domain protein
FR741_20205	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FR741_20215	COG1629	transport
FR741_20215	COG4771	TonB-dependent receptor
FR741_20220	COG0583	DNA-binding transcription factor activity
FR741_20225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR741_20225	COG0045	succinate-CoA ligase (ADP-forming) activity
FR741_20225	COG1042	CoA-binding domain protein
FR741_20235	COG1181	Belongs to the D-alanine--D-alanine ligase family
FR741_20245	COG0023	Translation Initiation Factor
FR741_20350	COG0583	DNA-binding transcription factor activity
FR741_20360	COG0589	response to stress
FR741_20365	COG3140	Belongs to the UPF0181 family
FR741_20390	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FR741_20395	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FR741_20420	COG5001	Diguanylate cyclase
FR741_20420	COG3706	GGDEF domain
FR741_20420	COG4251	negative regulation of phosphorylation
FR741_20420	COG2203	Gaf domain
FR741_20430	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FR741_20435	COG4149	molybdate abc transporter
FR741_20440	COG0725	ABC transporter, periplasmic molybdate-binding protein
FR741_20460	COG0189	ligase activity
FR741_20460	COG4067	protein conserved in archaea
FR741_20470	COG2207	Transcriptional regulator
FR741_20475	COG0534	Mate efflux family protein
FR741_20480	COG0602	queuosine metabolic process
FR741_20485	COG1328	CTP reductase activity
FR741_20500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR741_20530	COG1794	racemase activity, acting on amino acids and derivatives
FR741_20535	COG0384	phenazine biosynthesis protein PhzF
FR741_20545	COG0243	molybdopterin cofactor binding
FR741_20555	COG0583	DNA-binding transcription factor activity
FR741_20560	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FR741_20570	COG2197	response regulator
FR741_20575	COG3851	Histidine kinase
FR741_20580	COG2271	Major facilitator Superfamily
FR741_20605	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FR741_20610	COG3118	belongs to the thioredoxin family
FR741_20645	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FR741_20665	COG2116	formate transmembrane transporter activity
FR741_20675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR741_20680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FR741_20690	COG5001	Diguanylate cyclase
FR741_20770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FR741_20805	COG0277	FAD linked oxidase domain protein
FR741_20810	COG0583	DNA-binding transcription factor activity
FR741_20825	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FR741_20840	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FR741_20850	COG1288	antiporter activity
FR741_20860	COG3040	lipid binding
FR741_20870	COG0419	ATPase involved in DNA repair
FR741_20875	COG0420	3'-5' exonuclease activity
FR741_20890	COG3501	Rhs element vgr protein
FR741_20945	COG0631	protein serine/threonine phosphatase activity
FR741_20980	COG2815	serine threonine protein kinase
FR741_20980	COG0515	serine threonine protein kinase
FR741_21010	COG0625	glutathione transferase activity
FR741_21030	COG2146	nitrite reductase [NAD(P)H] activity
FR741_21030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR741_21035	COG1116	anion transmembrane transporter activity
FR741_21040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FR741_21045	COG1116	anion transmembrane transporter activity
FR741_21045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FR741_21075	COG0243	molybdopterin cofactor binding
FR741_21085	COG0814	amino acid
FR741_21095	COG3706	GGDEF domain
FR741_21145	COG2847	Copper chaperone PCu(A)C
FR741_21150	COG0443	Heat shock 70 kDa protein
FR741_21220	COG4160	amino acid transport
FR741_21225	COG4215	(ABC) transporter
FR741_21230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR741_21235	COG1126	abc transporter atp-binding protein
FR741_21265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FR741_21275	COG1012	belongs to the aldehyde dehydrogenase family
FR741_21295	COG1902	pentaerythritol trinitrate reductase activity
FR741_21295	COG0446	pyridine nucleotide-disulphide oxidoreductase
FR741_21300	COG0109	protoheme IX farnesyltransferase activity
FR741_21305	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FR741_21310	COG1845	cytochrome c oxidase, subunit III
FR741_21315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FR741_21320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FR741_21325	COG1028	Short-chain dehydrogenase reductase Sdr
FR741_21335	COG1024	Enoyl-CoA hydratase
FR741_21340	COG1024	Enoyl-CoA hydratase
FR741_21355	COG0183	Belongs to the thiolase family
FR741_21365	COG1960	acyl-CoA dehydrogenase activity
FR741_21370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FR741_21375	COG1024	Enoyl-CoA hydratase
FR741_21385	COG5413	integral membrane protein
FR741_21450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FR741_21465	COG0513	Belongs to the DEAD box helicase family
FR741_21470	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FR741_21500	COG0840	transmembrane signaling receptor activity
FR741_21505	COG1119	ATPase activity
FR741_21510	COG2200	EAL domain
FR741_21530	COG0513	Belongs to the DEAD box helicase family
FR741_21535	COG0523	cobalamin synthesis protein
FR741_21545	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FR741_21555	COG1278	Cold shock
FR741_21560	COG0557	exoribonuclease II activity
FR741_21565	COG0133	tryptophan synthase activity
FR741_21575	COG4628	conserved protein (DUF2132)
FR741_21580	COG0513	Belongs to the DEAD box helicase family
FR741_21585	COG2814	Major facilitator Superfamily
FR741_21600	COG0730	response to heat
FR741_21650	COG1404	Belongs to the peptidase S8 family
FR741_21670	COG3530	Putative quorum-sensing-regulated virulence factor
FR741_21695	COG3186	Phenylalanine-4-hydroxylase
FR741_21700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FR741_21705	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FR741_21730	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FR741_21735	COG1454	alcohol dehydrogenase
FR741_21740	COG2133	pyrroloquinoline quinone binding
FR741_21750	COG0783	Belongs to the Dps family
FR741_21755	COG0840	transmembrane signaling receptor activity
FR741_21765	COG1136	(ABC) transporter
FR741_21765	COG0577	efflux transmembrane transporter activity
FR741_21785	COG2199	diguanylate cyclase activity
FR741_21790	COG3036	rescue of stalled ribosome
FR741_21795	COG1278	Cold shock
FR741_21815	COG2885	chlorophyll binding
FR741_21825	COG0545	Peptidyl-prolyl cis-trans isomerase
FR741_21830	COG0109	protoheme IX farnesyltransferase activity
FR741_21835	COG1612	heme a metabolic process
FR741_21855	COG1845	cytochrome c oxidase, subunit III
FR741_21860	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FR741_21865	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FR741_21870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FR741_21875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FR741_21885	COG1280	lysine exporter protein (LysE YggA)
FR741_21890	COG2207	Transcriptional regulator
FR741_21905	COG0179	Fumarylacetoacetate (FAA) hydrolase
FR741_21925	COG0697	spore germination
FR741_21945	COG2814	Major facilitator Superfamily
FR741_21950	COG0583	DNA-binding transcription factor activity
FR741_21955	COG5001	Diguanylate cyclase
FR741_21960	COG0739	heme binding
FR741_21990	COG0840	transmembrane signaling receptor activity
FR741_22000	COG0814	amino acid
FR741_22015	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FR741_22020	COG1072	(Pantothenic acid kinase))
FR741_22030	COG1063	alcohol dehydrogenase
FR741_22035	COG2213	PTS system mannitol-specific
FR741_22040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR741_22060	COG0798	PFAM Bile acid sodium symporter
FR741_22070	COG1881	PFAM PEBP family protein
FR741_22080	COG2706	6-phosphogluconolactonase activity
FR741_22090	COG1131	(ABC) transporter
FR741_22095	COG0842	Transport permease protein
FR741_22110	COG3383	formate dehydrogenase (NAD+) activity
FR741_22135	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FR741_22165	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FR741_22185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FR741_22195	COG1505	serine-type exopeptidase activity
FR741_22200	COG0488	(ABC) transporter
FR741_22205	COG0589	response to stress
FR741_22210	COG2249	NAD(P)H dehydrogenase (quinone) activity
FR741_22230	COG0366	Alpha amylase catalytic
FR741_22235	COG0789	Transcriptional regulator
FR741_22250	COG4934	collagen metabolic process
FR741_22260	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FR741_22265	COG0583	DNA-binding transcription factor activity
FR741_22300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FR741_22305	COG0835	chemotaxis
FR741_22305	COG0784	Response regulator, receiver
FR741_22315	COG0748	coenzyme F420 binding
FR741_22320	COG3721	Heme iron utilization protein
FR741_22330	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FR741_22335	COG0811	peptide transport
FR741_22340	COG0848	biopolymer transport protein
FR741_22350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR741_22355	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FR741_22395	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FR741_22400	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FR741_22405	COG0633	Ferredoxin
FR741_22405	COG3217	Mosc domain protein beta barrel domain protein
FR741_22405	COG3217	Mosc domain protein beta barrel domain protein
FR741_22405	COG0633	Ferredoxin
FR741_22410	COG0401	homolog of Blt101
FR741_22420	COG0418	dihydroorotase activity
FR741_22425	COG2354	Protein conserved in bacteria
FR741_22455	COG3833	ABC-type maltose transport systems, permease component
FR741_22460	COG1175	transmembrane transport
FR741_22470	COG3842	ATPase activity
FR741_22475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FR741_22490	COG0489	protein tyrosine kinase activity
FR741_22490	COG3206	protein involved in exopolysaccharide biosynthesis
FR741_22535	COG1309	transcriptional regulator
FR741_22540	COG2130	NADP-dependent
FR741_22550	COG0753	catalase activity
FR741_22555	COG2084	Dehydrogenase
FR741_22560	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR741_22565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR741_22575	COG2207	Transcriptional regulator
FR741_22580	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR741_22580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FR741_22580	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FR741_22610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FR741_22615	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FR741_22620	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FR741_22630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FR741_22635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FR741_22640	COG1012	belongs to the aldehyde dehydrogenase family
FR741_22655	COG0583	DNA-binding transcription factor activity
FR741_22660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FR741_22665	COG0569	domain protein
FR741_22675	COG2205	protein histidine kinase activity
FR741_22680	COG1132	(ABC) transporter
FR741_22685	COG4774	siderophore transport
FR741_22690	COG1120	ATPase activity
FR741_22695	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FR741_22730	COG2197	response regulator
FR741_22740	COG0840	transmembrane signaling receptor activity
FR741_22750	COG0714	Associated with various cellular activities
FR741_22765	COG2304	oxidoreductase activity
FR741_22770	COG2304	oxidoreductase activity
FR741_22785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FR741_22790	COG0581	inorganic phosphate transmembrane transporter activity
FR741_22795	COG0573	inorganic phosphate transmembrane transporter activity
FR741_22825	COG4771	TonB-dependent receptor
FR741_22830	COG1770	oligopeptidase
FR741_22835	COG0513	Belongs to the DEAD box helicase family
FR741_22845	COG0110	maltose O-acetyltransferase activity
FR741_22915	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FR741_22965	COG4695	Portal protein
FR741_23045	COG1376	ErfK ybiS ycfS ynhG family protein
FR741_23045	COG1388	LysM domain
FR741_23050	COG0415	Belongs to the DNA photolyase family
FR741_23055	COG0789	Transcriptional regulator
FR741_23060	COG3272	Protein of unknown function (DUF1722)
FR741_23065	COG0813	purine-nucleoside phosphorylase activity
FR741_23080	COG3706	GGDEF domain
FR741_23090	COG1566	PFAM secretion protein HlyD family protein
FR741_23095	COG4720	Psort location CytoplasmicMembrane, score
FR741_23100	COG1122	ATPase activity
FR741_23120	COG0348	domain, Protein
FR741_23125	COG0437	4 iron, 4 sulfur cluster binding
FR741_23130	COG1247	-acetyltransferase
FR741_23150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR741_23155	COG0840	transmembrane signaling receptor activity
FR741_23160	COG1067	ATP-dependent peptidase activity
FR741_23170	COG4172	Belongs to the ABC transporter superfamily
FR741_23175	COG1505	serine-type exopeptidase activity
FR741_23180	COG0583	DNA-binding transcription factor activity
FR741_23185	COG1620	l-lactate permease
FR741_23190	COG1304	FMN binding
FR741_23200	COG0668	transmembrane transport
FR741_23235	COG1063	alcohol dehydrogenase
FR741_23240	COG0156	8-amino-7-oxononanoate synthase activity
FR741_23245	COG3300	MHYT domain
FR741_23245	COG5001	Diguanylate cyclase
FR741_23250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FR741_23270	COG0745	RESPONSE REGULATOR receiver
FR741_23295	COG0346	lactoylglutathione lyase activity
FR741_23350	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FR741_23390	COG1987	bacterial-type flagellum assembly
FR741_23400	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FR741_23415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FR741_23430	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FR741_23435	COG1516	flagellar protein fliS
FR741_23450	COG1580	Controls the rotational direction of flagella during chemotaxis
FR741_23455	COG1191	sigma factor activity
FR741_23460	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FR741_23465	COG1360	Flagellar Motor Protein
FR741_23520	COG1882	Formate acetyltransferase
FR741_23525	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FR741_23530	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FR741_23540	COG0454	-acetyltransferase
FR741_23550	COG2814	Major facilitator Superfamily
FR741_23585	COG1566	PFAM secretion protein HlyD family protein
FR741_23595	COG0628	permease
FR741_23600	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FR741_23615	COG4628	conserved protein (DUF2132)
FR741_23620	COG0583	DNA-binding transcription factor activity
FR741_23645	COG1686	Belongs to the peptidase S11 family
FR741_23665	COG0415	Belongs to the DNA photolyase family
FR741_23670	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FR741_23675	COG3397	chitin binding
FR741_23680	COG4667	esterase of the alpha-beta hydrolase superfamily
FR741_23685	COG2095	MarC family integral membrane protein
FR741_23700	COG1596	polysaccharide export
FR741_23720	COG1301	dicarboxylic acid transport
FR741_23735	COG3339	Conserved Protein
FR741_23740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FR741_23745	COG0700	Nucleoside recognition
FR741_23750	COG3366	ferrous iron transmembrane transporter activity
FR741_23765	COG0366	Alpha amylase catalytic
FR741_23770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FR741_23775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FR741_23780	COG1640	4-alpha-glucanotransferase
FR741_23785	COG0058	SHG alpha-glucan phosphorylase activity
FR741_23795	COG2909	trisaccharide binding
FR741_23810	COG1999	signal sequence binding
FR741_23815	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR741_23815	COG1263	PTS System
FR741_23820	COG1162	GTPase activity
FR741_23825	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FR741_23830	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FR741_23840	COG0531	amino acid
FR741_23845	COG1982	Orn Lys Arg decarboxylase major
FR741_23865	COG2356	endonuclease I
FR741_23885	COG4580	involved in the transport of maltose and maltodextrins
FR741_23925	COG0739	heme binding
FR741_23935	COG0612	Peptidase, M16
FR741_23940	COG0840	transmembrane signaling receptor activity
FR741_23945	COG1120	ATPase activity
FR741_23950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR741_23955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FR741_23960	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FR741_23965	COG4772	TonB-dependent receptor
FR741_23990	COG4264	IucA IucC family
FR741_23995	COG0019	diaminopimelate decarboxylase activity
FR741_24000	COG1653	transport
FR741_24010	COG0745	RESPONSE REGULATOR receiver
FR741_24035	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FR741_24045	COG0463	Glycosyl transferase, family 2
FR741_24060	COG1136	(ABC) transporter
FR741_24080	COG1764	response to oxidative stress
FR741_24085	COG1846	Transcriptional regulator
FR741_24095	COG3634	alkyl hydroperoxide reductase activity
FR741_24130	COG1595	DNA-templated transcription, initiation
FR741_24150	COG2258	MOSC domain
FR741_24175	COG2207	Transcriptional regulator
FR741_24185	COG1132	(ABC) transporter
FR741_24220	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FR741_24245	COG0259	pyridoxamine-phosphate oxidase activity
FR741_24300	COG4166	transmembrane transport
FR741_24320	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FR741_24325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FR741_24325	COG1263	PTS System
FR741_24330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FR741_24335	COG3340	Belongs to the peptidase S51 family
FR741_24355	COG1444	tRNA N-acetyltransferase activity