locus-tag	class	description
AL552_00010	COG1012	belongs to the aldehyde dehydrogenase family
AL552_00025	COG1902	pentaerythritol trinitrate reductase activity
AL552_00025	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL552_00035	COG0109	protoheme IX farnesyltransferase activity
AL552_00040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL552_00045	COG1845	cytochrome c oxidase, subunit III
AL552_00050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL552_00055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL552_00060	COG1028	Short-chain dehydrogenase reductase Sdr
AL552_00070	COG1024	Enoyl-CoA hydratase
AL552_00075	COG1024	Enoyl-CoA hydratase
AL552_00090	COG0183	Belongs to the thiolase family
AL552_00100	COG1960	acyl-CoA dehydrogenase activity
AL552_00105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL552_00110	COG1024	Enoyl-CoA hydratase
AL552_00120	COG5413	integral membrane protein
AL552_00130	COG0277	FAD linked oxidase domain protein
AL552_00130	COG0247	lactate metabolic process
AL552_00185	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL552_00200	COG0513	Belongs to the DEAD box helicase family
AL552_00205	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AL552_00220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL552_00245	COG0582	viral genome integration into host DNA
AL552_00285	COG0840	transmembrane signaling receptor activity
AL552_00290	COG1119	ATPase activity
AL552_00295	COG2200	EAL domain
AL552_00315	COG0513	Belongs to the DEAD box helicase family
AL552_00320	COG0523	cobalamin synthesis protein
AL552_00330	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AL552_00340	COG1278	Cold shock
AL552_00345	COG0557	exoribonuclease II activity
AL552_00350	COG0133	tryptophan synthase activity
AL552_00360	COG4628	conserved protein (DUF2132)
AL552_00365	COG0513	Belongs to the DEAD box helicase family
AL552_00375	COG0730	response to heat
AL552_00445	COG2207	Transcriptional regulator
AL552_00450	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AL552_00460	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL552_00465	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL552_00515	COG1404	Belongs to the peptidase S8 family
AL552_00535	COG3530	Putative quorum-sensing-regulated virulence factor
AL552_00560	COG3186	Phenylalanine-4-hydroxylase
AL552_00565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL552_00570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL552_00590	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL552_00595	COG1454	alcohol dehydrogenase
AL552_00600	COG2133	pyrroloquinoline quinone binding
AL552_00610	COG0783	Belongs to the Dps family
AL552_00625	COG1136	(ABC) transporter
AL552_00625	COG0577	efflux transmembrane transporter activity
AL552_00645	COG2199	diguanylate cyclase activity
AL552_00650	COG3036	rescue of stalled ribosome
AL552_00655	COG1278	Cold shock
AL552_00675	COG2885	chlorophyll binding
AL552_00685	COG0545	Peptidyl-prolyl cis-trans isomerase
AL552_00690	COG0109	protoheme IX farnesyltransferase activity
AL552_00695	COG1612	heme a metabolic process
AL552_00720	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AL552_00725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL552_00730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL552_00735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL552_00745	COG1280	lysine exporter protein (LysE YggA)
AL552_00750	COG2207	Transcriptional regulator
AL552_00765	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL552_00780	COG0697	spore germination
AL552_00800	COG2814	Major facilitator Superfamily
AL552_00805	COG0583	DNA-binding transcription factor activity
AL552_00810	COG5001	Diguanylate cyclase
AL552_00815	COG0739	heme binding
AL552_00850	COG0840	transmembrane signaling receptor activity
AL552_00860	COG0814	amino acid
AL552_00880	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL552_00885	COG1072	(Pantothenic acid kinase))
AL552_00895	COG1063	alcohol dehydrogenase
AL552_00900	COG2213	PTS system mannitol-specific
AL552_00905	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL552_00925	COG0798	PFAM Bile acid sodium symporter
AL552_00935	COG1881	PFAM PEBP family protein
AL552_00945	COG2706	6-phosphogluconolactonase activity
AL552_00965	COG1131	(ABC) transporter
AL552_00970	COG0842	Transport permease protein
AL552_00985	COG3383	formate dehydrogenase (NAD+) activity
AL552_01010	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL552_01040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL552_01050	COG2067	long-chain fatty acid transport protein
AL552_01060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL552_01070	COG1505	serine-type exopeptidase activity
AL552_01075	COG0488	(ABC) transporter
AL552_01080	COG0589	response to stress
AL552_01085	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL552_01105	COG0366	Alpha amylase catalytic
AL552_01110	COG0789	Transcriptional regulator
AL552_01125	COG4934	collagen metabolic process
AL552_01140	COG0583	DNA-binding transcription factor activity
AL552_01175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL552_01180	COG0784	Response regulator, receiver
AL552_01180	COG0835	chemotaxis
AL552_01190	COG0748	coenzyme F420 binding
AL552_01195	COG3721	Heme iron utilization protein
AL552_01205	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL552_01210	COG0811	peptide transport
AL552_01215	COG0848	biopolymer transport protein
AL552_01225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL552_01230	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL552_01275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL552_01280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AL552_01290	COG0401	homolog of Blt101
AL552_01300	COG0418	dihydroorotase activity
AL552_01305	COG2354	Protein conserved in bacteria
AL552_01335	COG3833	ABC-type maltose transport systems, permease component
AL552_01340	COG1175	transmembrane transport
AL552_01350	COG3842	ATPase activity
AL552_01370	COG3206	protein involved in exopolysaccharide biosynthesis
AL552_01370	COG0489	protein tyrosine kinase activity
AL552_01415	COG1309	transcriptional regulator
AL552_01420	COG2130	NADP-dependent
AL552_01430	COG0753	catalase activity
AL552_01435	COG2084	Dehydrogenase
AL552_01440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL552_01445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL552_01455	COG2207	Transcriptional regulator
AL552_01460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL552_01460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL552_01460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL552_01490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL552_01495	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL552_01500	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL552_01510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL552_01515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL552_01535	COG0583	DNA-binding transcription factor activity
AL552_01545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL552_01575	COG3842	ATPase activity
AL552_01605	COG1566	PFAM secretion protein HlyD family protein
AL552_01610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL552_01650	COG0583	DNA-binding transcription factor activity
AL552_01660	COG4948	Mandelate Racemase Muconate Lactonizing
AL552_01670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL552_01695	COG1342	Belongs to the UPF0251 family
AL552_01705	COG4176	ABC-type proline glycine betaine transport system permease component
AL552_01710	COG4175	Glycine betaine
AL552_01710	COG3448	diguanylate cyclase activity
AL552_01715	COG3015	lipoprotein NlpE involved in copper resistance
AL552_01720	COG3713	MltA-interacting MipA family protein
AL552_01735	COG0583	DNA-binding transcription factor activity
AL552_01760	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL552_01770	COG1335	isochorismatase
AL552_01780	COG1349	DNA-binding transcription factor activity
AL552_01785	COG0346	lactoylglutathione lyase activity
AL552_01800	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL552_01805	COG2070	2-Nitropropane dioxygenase
AL552_01810	COG0531	amino acid
AL552_01820	COG4303	Ethanolamine ammonia lyase large subunit
AL552_01825	COG2207	Transcriptional regulator
AL552_01830	COG1309	transcriptional regulator
AL552_01850	COG1280	lysine exporter protein (LysE YggA)
AL552_01865	COG0459	protein refolding
AL552_01870	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL552_01875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL552_01890	COG1304	FMN binding
AL552_01910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL552_01925	COG1706	bacterial-type flagellum-dependent cell motility
AL552_01930	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL552_01935	COG4786	Flagellar basal body rod
AL552_01940	COG4787	bacterial-type flagellum-dependent cell motility
AL552_01945	COG1749	Flagellar hook protein flgE
AL552_01950	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL552_01955	COG1558	bacterial-type flagellum-dependent cell motility
AL552_01960	COG1815	bacterial-type flagellum-dependent cell motility
AL552_01980	COG0741	lytic transglycosylase activity
AL552_01985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL552_02005	COG1760	l-serine dehydratase
AL552_02030	COG0583	DNA-binding transcription factor activity
AL552_02040	COG2866	Carboxypeptidase
AL552_02045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL552_02055	COG2990	Protein conserved in bacteria
AL552_02080	COG3842	ATPase activity
AL552_02085	COG1840	ABC-type Fe3 transport system, periplasmic component
AL552_02100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL552_02105	COG1609	Transcriptional regulator
AL552_02135	COG3240	lipase activity
AL552_02140	COG2067	long-chain fatty acid transport protein
AL552_02145	COG3338	carbonate dehydratase activity
AL552_02150	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL552_02165	COG1011	Hydrolase
AL552_02205	COG0110	maltose O-acetyltransferase activity
AL552_02210	COG1765	OsmC-like protein
AL552_02215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL552_02215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL552_02230	COG3046	protein related to deoxyribodipyrimidine photolyase
AL552_02235	COG0415	Belongs to the DNA photolyase family
AL552_02240	COG3706	GGDEF domain
AL552_02255	COG3706	GGDEF domain
AL552_02270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL552_02290	COG3033	Beta-eliminating lyase
AL552_02300	COG1271	oxidase subunit
AL552_02305	COG1294	oxidase, subunit
AL552_02320	COG0579	oxidoreductase
AL552_02345	COG2199	diguanylate cyclase activity
AL552_02355	COG4191	Histidine kinase
AL552_02390	COG0583	DNA-binding transcription factor activity
AL552_02395	COG0189	ligase activity
AL552_02400	COG4067	protein conserved in archaea
AL552_02400	COG0189	ligase activity
AL552_02410	COG1166	arginine decarboxylase activity
AL552_02415	COG0010	Belongs to the arginase family
AL552_02420	COG2814	Major facilitator Superfamily
AL552_02425	COG1770	oligopeptidase
AL552_02440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL552_02445	COG1121	(ABC) transporter
AL552_02495	COG0848	biopolymer transport protein
AL552_02500	COG0811	peptide transport
AL552_02505	COG0811	peptide transport
AL552_02525	COG0745	RESPONSE REGULATOR receiver
AL552_02535	COG0584	glycerophosphoryl diester phosphodiesterase
AL552_02545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL552_02605	COG1901	pseudouridine methyltransferase
AL552_02610	COG0312	modulator of DNA gyrase
AL552_02615	COG0312	modulator of DNA gyrase
AL552_02620	COG0351	phosphomethylpyrimidine kinase
AL552_02625	COG1116	anion transmembrane transporter activity
AL552_02630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL552_02635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL552_02640	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL552_02645	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AL552_02650	COG0352	thiamine-phosphate diphosphorylase activity
AL552_02660	COG0243	molybdopterin cofactor binding
AL552_02665	COG3005	denitrification pathway
AL552_02670	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL552_02675	COG1028	Short-chain dehydrogenase reductase Sdr
AL552_02690	COG0456	acetyltransferase
AL552_02705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL552_02710	COG1929	Belongs to the glycerate kinase type-1 family
AL552_02715	COG2610	gluconate transmembrane transporter activity
AL552_02720	COG3835	regulator
AL552_02745	COG0546	phosphoglycolate phosphatase activity
AL552_02760	COG0583	DNA-binding transcription factor activity
AL552_02780	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AL552_02785	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AL552_02785	COG3408	Glycogen debranching enzyme
AL552_02815	COG3047	cAMP biosynthetic process
AL552_02820	COG1357	PFAM Pentapeptide repeats (8 copies)
AL552_02855	COG2375	cellular response to nickel ion
AL552_02860	COG0583	DNA-binding transcription factor activity
AL552_02865	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AL552_02870	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AL552_02885	COG2199	diguanylate cyclase activity
AL552_02895	COG0561	phosphatase activity
AL552_02900	COG0583	DNA-binding transcription factor activity
AL552_02915	COG0564	pseudouridine synthase activity
AL552_02920	COG0534	Mate efflux family protein
AL552_02940	COG3123	guanosine phosphorylase activity
AL552_02955	COG0596	Alpha beta hydrolase
AL552_02980	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL552_02990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL552_02995	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL552_03005	COG2259	Doxx family
AL552_03010	COG1741	Belongs to the pirin family
AL552_03030	COG0363	glucosamine-6-phosphate deaminase activity
AL552_03040	COG0786	glutamate:sodium symporter activity
AL552_03045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL552_03060	COG0786	glutamate:sodium symporter activity
AL552_03085	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL552_03095	COG3279	Response regulator of the LytR AlgR family
AL552_03100	COG3275	phosphorelay sensor kinase activity
AL552_03120	COG1136	(ABC) transporter
AL552_03135	COG0772	Belongs to the SEDS family
AL552_03160	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL552_03160	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AL552_03170	COG0444	Belongs to the ABC transporter superfamily
AL552_03175	COG4608	Belongs to the ABC transporter superfamily
AL552_03200	COG1444	tRNA N-acetyltransferase activity
AL552_03225	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL552_03230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL552_03230	COG1263	PTS System
AL552_03235	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL552_03255	COG4166	transmembrane transport
AL552_03305	COG0259	pyridoxamine-phosphate oxidase activity
AL552_03330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL552_03365	COG1132	(ABC) transporter
AL552_03375	COG2207	Transcriptional regulator
AL552_03400	COG2258	MOSC domain
AL552_03420	COG1595	DNA-templated transcription, initiation
AL552_03455	COG3634	alkyl hydroperoxide reductase activity
AL552_03460	COG0450	alkyl hydroperoxide reductase
AL552_03465	COG1846	Transcriptional regulator
AL552_03470	COG1764	response to oxidative stress
AL552_03490	COG1136	(ABC) transporter
AL552_03510	COG0463	Glycosyl transferase, family 2
AL552_03520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL552_03545	COG0745	RESPONSE REGULATOR receiver
AL552_03555	COG1653	transport
AL552_03560	COG0019	diaminopimelate decarboxylase activity
AL552_03565	COG4264	IucA IucC family
AL552_03590	COG4772	TonB-dependent receptor
AL552_03595	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL552_03600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL552_03605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL552_03610	COG1120	ATPase activity
AL552_03620	COG0612	Peptidase, M16
AL552_03630	COG0739	heme binding
AL552_03665	COG1609	Transcriptional regulator
AL552_03690	COG1760	l-serine dehydratase
AL552_03720	COG2356	endonuclease I
AL552_03740	COG1982	Orn Lys Arg decarboxylase major
AL552_03745	COG0531	amino acid
AL552_03755	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
AL552_03760	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL552_03765	COG1162	GTPase activity
AL552_03770	COG1263	PTS System
AL552_03770	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL552_03775	COG1999	signal sequence binding
AL552_03790	COG2909	trisaccharide binding
AL552_03800	COG0058	SHG alpha-glucan phosphorylase activity
AL552_03805	COG1640	4-alpha-glucanotransferase
AL552_03810	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL552_03815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL552_03820	COG0366	Alpha amylase catalytic
AL552_03835	COG3366	ferrous iron transmembrane transporter activity
AL552_03840	COG0700	Nucleoside recognition
AL552_03845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL552_03850	COG3339	Conserved Protein
AL552_03855	COG1301	dicarboxylic acid transport
AL552_03875	COG1596	polysaccharide export
AL552_03890	COG2095	MarC family integral membrane protein
AL552_03895	COG4667	esterase of the alpha-beta hydrolase superfamily
AL552_03900	COG3397	chitin binding
AL552_03905	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL552_03910	COG0415	Belongs to the DNA photolyase family
AL552_03935	COG1686	Belongs to the peptidase S11 family
AL552_03960	COG0583	DNA-binding transcription factor activity
AL552_03965	COG4628	conserved protein (DUF2132)
AL552_03980	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL552_03985	COG0628	permease
AL552_03995	COG1566	PFAM secretion protein HlyD family protein
AL552_04030	COG2814	Major facilitator Superfamily
AL552_04040	COG0454	-acetyltransferase
AL552_04050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL552_04055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL552_04115	COG1360	Flagellar Motor Protein
AL552_04120	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL552_04125	COG1191	sigma factor activity
AL552_04130	COG1580	Controls the rotational direction of flagella during chemotaxis
AL552_04145	COG1516	flagellar protein fliS
AL552_04150	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL552_04160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL552_04175	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL552_04185	COG1987	bacterial-type flagellum assembly
AL552_04210	COG2204	response regulator
AL552_04225	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL552_04280	COG0346	lactoylglutathione lyase activity
AL552_04305	COG0745	RESPONSE REGULATOR receiver
AL552_04325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL552_04330	COG5001	Diguanylate cyclase
AL552_04330	COG3300	MHYT domain
AL552_04335	COG0156	8-amino-7-oxononanoate synthase activity
AL552_04340	COG1063	alcohol dehydrogenase
AL552_04350	COG0668	transmembrane transport
AL552_04360	COG1304	FMN binding
AL552_04365	COG1620	l-lactate permease
AL552_04370	COG0583	DNA-binding transcription factor activity
AL552_04375	COG1505	serine-type exopeptidase activity
AL552_04380	COG4172	Belongs to the ABC transporter superfamily
AL552_04400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL552_04420	COG1247	-acetyltransferase
AL552_04425	COG0437	4 iron, 4 sulfur cluster binding
AL552_04430	COG0348	domain, Protein
AL552_04450	COG1122	ATPase activity
AL552_04455	COG4720	Psort location CytoplasmicMembrane, score
AL552_04460	COG1566	PFAM secretion protein HlyD family protein
AL552_04470	COG3706	GGDEF domain
AL552_04485	COG0813	purine-nucleoside phosphorylase activity
AL552_04495	COG3272	Protein of unknown function (DUF1722)
AL552_04500	COG0789	Transcriptional regulator
AL552_04505	COG0415	Belongs to the DNA photolyase family
AL552_04510	COG1376	ErfK ybiS ycfS ynhG family protein
AL552_04510	COG1388	LysM domain
AL552_04520	COG0513	Belongs to the DEAD box helicase family
AL552_04525	COG1770	oligopeptidase
AL552_04530	COG4771	TonB-dependent receptor
AL552_04555	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL552_04560	COG0573	inorganic phosphate transmembrane transporter activity
AL552_04565	COG0581	inorganic phosphate transmembrane transporter activity
AL552_04570	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL552_04585	COG2304	oxidoreductase activity
AL552_04590	COG2304	oxidoreductase activity
AL552_04605	COG0714	Associated with various cellular activities
AL552_04615	COG0840	transmembrane signaling receptor activity
AL552_04660	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL552_04665	COG1120	ATPase activity
AL552_04670	COG4774	siderophore transport
AL552_04675	COG1132	(ABC) transporter
AL552_04700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL552_04715	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL552_04720	COG2197	response regulator
AL552_04735	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL552_04740	COG0252	asparaginase activity
AL552_04750	COG0583	DNA-binding transcription factor activity
AL552_04760	COG1280	lysine exporter protein (LysE YggA)
AL552_04765	COG3122	Protein conserved in bacteria
AL552_04775	COG2423	ornithine cyclodeaminase activity
AL552_04780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL552_04785	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL552_04790	COG1012	belongs to the aldehyde dehydrogenase family
AL552_04795	COG1522	sequence-specific DNA binding
AL552_04800	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL552_04810	COG3608	succinylglutamate desuccinylase aspartoacylase
AL552_04820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL552_04825	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL552_04830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL552_04835	COG2207	Transcriptional regulator
AL552_04840	COG1028	Short-chain dehydrogenase reductase Sdr
AL552_04850	COG1063	alcohol dehydrogenase
AL552_04855	COG1902	pentaerythritol trinitrate reductase activity
AL552_04870	COG0583	DNA-binding transcription factor activity
AL552_04880	COG0513	Belongs to the DEAD box helicase family
AL552_04920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL552_04925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL552_04925	COG2207	Transcriptional regulator
AL552_04945	COG3746	phosphate-selective porin O and P
AL552_04960	COG1028	Short-chain dehydrogenase reductase Sdr
AL552_04985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL552_04985	COG1263	PTS System
AL552_04990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL552_04995	COG1621	beta-fructofuranosidase activity
AL552_05005	COG0625	glutathione transferase activity
AL552_05015	COG1686	Belongs to the peptidase S11 family
AL552_05030	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL552_05045	COG1278	Cold shock
AL552_05050	COG1741	Belongs to the pirin family
AL552_05055	COG4667	esterase of the alpha-beta hydrolase superfamily
AL552_05080	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL552_05090	COG2205	protein histidine kinase activity
AL552_05095	COG0745	RESPONSE REGULATOR receiver
AL552_05110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL552_05130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL552_05140	COG2814	Major facilitator Superfamily
AL552_05155	COG1418	mRNA catabolic process
AL552_05160	COG0402	S-adenosylhomocysteine deaminase activity
AL552_05165	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL552_05170	COG2239	Acts as a magnesium transporter
AL552_05175	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL552_05180	COG1566	PFAM secretion protein HlyD family protein
AL552_05205	COG0745	RESPONSE REGULATOR receiver
AL552_05210	COG2205	protein histidine kinase activity
AL552_05225	COG0531	amino acid
AL552_05265	COG5002	protein histidine kinase activity
AL552_05265	COG0784	Response regulator, receiver
AL552_05265	COG2205	protein histidine kinase activity
AL552_05290	COG2827	Endonuclease containing a URI domain
AL552_05300	COG1879	ABC-type sugar transport system periplasmic component
AL552_05305	COG2205	protein histidine kinase activity
AL552_05305	COG0784	Response regulator, receiver
AL552_05365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL552_05380	COG1280	lysine exporter protein (LysE YggA)
AL552_05395	COG0183	Belongs to the thiolase family
AL552_05405	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL552_05415	COG3005	denitrification pathway
AL552_05425	COG0243	molybdopterin cofactor binding
AL552_05435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL552_05440	COG3850	Histidine kinase
AL552_05445	COG2197	response regulator
AL552_05480	COG0840	transmembrane signaling receptor activity
AL552_05490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL552_05505	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL552_05510	COG2814	Major facilitator Superfamily
AL552_05515	COG0840	transmembrane signaling receptor activity
AL552_05520	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL552_05525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL552_05555	COG2897	thiosulfate sulfurtransferase activity
AL552_05575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL552_05590	COG1914	H( )-stimulated, divalent metal cation uptake system
AL552_05600	COG0038	chloride channel
AL552_05615	COG4989	oxidoreductase activity
AL552_05630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL552_05630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL552_05640	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AL552_05685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL552_05700	COG1013	pyruvate-flavodoxin oxidoreductase activity
AL552_05730	COG2814	Major facilitator Superfamily
AL552_05750	COG0589	response to stress
AL552_05760	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AL552_05760	COG2111	Na H antiporter
AL552_05780	COG2212	antiporter activity
AL552_05785	COG1320	monovalent cation:proton antiporter activity
AL552_05790	COG2188	Transcriptional regulator
AL552_05795	COG1486	melibiose metabolic process
AL552_05800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL552_05800	COG1263	PTS System
AL552_05805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL552_05835	COG1022	Amp-dependent synthetase and ligase
AL552_05890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL552_05905	COG3527	Alpha-acetolactate decarboxylase
AL552_05915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL552_05930	COG1294	oxidase, subunit
AL552_05935	COG1271	oxidase subunit
AL552_05940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL552_05945	COG0110	maltose O-acetyltransferase activity
AL552_05960	COG3850	Histidine kinase
AL552_05960	COG3437	response regulator, receiver
AL552_05960	COG2205	protein histidine kinase activity
AL552_05960	COG4999	Histidine kinase
AL552_05980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL552_05985	COG1960	acyl-CoA dehydrogenase activity
AL552_05995	COG0183	Belongs to the thiolase family
AL552_06005	COG1960	acyl-CoA dehydrogenase activity
AL552_06010	COG1024	Enoyl-CoA hydratase
AL552_06025	COG1028	Short-chain dehydrogenase reductase Sdr
AL552_06035	COG1309	transcriptional regulator
AL552_06040	COG1012	belongs to the aldehyde dehydrogenase family
AL552_06055	COG4176	ABC-type proline glycine betaine transport system permease component
AL552_06060	COG0517	IMP dehydrogenase activity
AL552_06060	COG4175	Glycine betaine
AL552_06075	COG0330	HflC and HflK could
AL552_06085	COG3300	MHYT domain
AL552_06085	COG5001	Diguanylate cyclase
AL552_06165	COG1869	D-ribose catabolic process
AL552_06170	COG1129	ABC transporter
AL552_06175	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL552_06180	COG1879	ABC-type sugar transport system periplasmic component
AL552_06185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL552_06190	COG1609	Transcriptional regulator
AL552_06215	COG4607	ABC-type enterochelin transport system periplasmic component
AL552_06220	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL552_06225	COG4605	iron ion homeostasis
AL552_06230	COG4604	ABC transporter, ATP-binding protein
AL552_06235	COG0789	Transcriptional regulator
AL552_06240	COG2207	Transcriptional regulator
AL552_06275	COG1289	transmembrane transporter activity
AL552_06280	COG0210	DNA helicase
AL552_06285	COG1803	Methylglyoxal synthase
AL552_06290	COG1879	ABC-type sugar transport system periplasmic component
AL552_06315	COG3119	arylsulfatase activity
AL552_06325	COG3119	arylsulfatase activity
AL552_06330	COG0641	radical SAM
AL552_06335	COG0714	Associated with various cellular activities
AL552_06365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL552_06365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL552_06370	COG0583	DNA-binding transcription factor activity
AL552_06375	COG1597	lipid kinase activity
AL552_06380	COG3111	PFAM Bacterial OB fold (BOF) protein
AL552_06405	COG0501	Belongs to the peptidase M48B family
AL552_06410	COG1704	LemA family
AL552_06415	COG3069	C4-dicarboxylate transmembrane transporter activity
AL552_06445	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AL552_06455	COG3706	GGDEF domain
AL552_06465	COG2197	response regulator
AL552_06470	COG0784	Response regulator, receiver
AL552_06470	COG0835	chemotaxis
AL552_06485	COG2962	Rard protein
AL552_06515	COG2076	Multidrug Resistance protein
AL552_06545	COG0069	glutamate synthase activity
AL552_06545	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL552_06550	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AL552_06575	COG1902	pentaerythritol trinitrate reductase activity
AL552_06580	COG0346	lactoylglutathione lyase activity
AL552_06605	COG2239	Acts as a magnesium transporter
AL552_06635	COG0242	peptide deformylase activity
AL552_06675	COG2176	DNA-directed DNA polymerase activity
AL552_06700	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL552_06710	COG0346	lactoylglutathione lyase activity
AL552_06715	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL552_06715	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL552_06720	COG0509	glycine decarboxylation via glycine cleavage system
AL552_06725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL552_06735	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL552_06745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL552_06765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL552_06765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL552_06765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL552_06775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL552_06775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL552_06780	COG1609	Transcriptional regulator
AL552_06795	COG2200	EAL domain
AL552_06795	COG2199	diguanylate cyclase activity
AL552_06795	COG2203	Gaf domain
AL552_06800	COG0765	amino acid transport
AL552_06805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL552_06810	COG0765	amino acid transport
AL552_06815	COG1126	abc transporter atp-binding protein
AL552_06820	COG0469	pyruvate kinase activity
AL552_06825	COG2271	Major facilitator Superfamily
AL552_06830	COG1840	ABC-type Fe3 transport system, periplasmic component
AL552_06850	COG1979	alcohol dehydrogenase
AL552_06865	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL552_06870	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AL552_06875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL552_06890	COG0546	phosphoglycolate phosphatase activity
AL552_06900	COG0840	transmembrane signaling receptor activity
AL552_06910	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AL552_06915	COG0513	Belongs to the DEAD box helicase family
AL552_06920	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL552_06935	COG3038	cytochrome b561
AL552_06940	COG2353	YceI-like domain
AL552_06945	COG2116	formate transmembrane transporter activity
AL552_06955	COG0583	DNA-binding transcription factor activity
AL552_06965	COG3593	DNA synthesis involved in DNA repair
AL552_06970	COG0737	Belongs to the 5'-nucleotidase family
AL552_07000	COG2067	long-chain fatty acid transport protein
AL552_07015	COG2050	protein possibly involved in aromatic compounds catabolism
AL552_07025	COG4533	DNA binding
AL552_07060	COG5001	Diguanylate cyclase
AL552_07060	COG1716	ATPase activity
AL552_07065	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL552_07075	COG4181	ATPase activity
AL552_07080	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL552_07090	COG1984	allophanate hydrolase subunit 2
AL552_07095	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL552_07100	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL552_07105	COG3447	MASE1 domain protein
AL552_07105	COG5001	Diguanylate cyclase
AL552_07105	COG5002	protein histidine kinase activity
AL552_07110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL552_07125	COG0583	DNA-binding transcription factor activity
AL552_07130	COG0045	succinate-CoA ligase (ADP-forming) activity
AL552_07130	COG1042	CoA-binding domain protein
AL552_07130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL552_07145	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL552_07155	COG0023	Translation Initiation Factor
AL552_07195	COG4128	Pfam Zonular occludens toxin
AL552_07230	COG0583	DNA-binding transcription factor activity
AL552_07240	COG0589	response to stress
AL552_07245	COG3140	Belongs to the UPF0181 family
AL552_07270	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL552_07275	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL552_07290	COG0745	RESPONSE REGULATOR receiver
AL552_07290	COG3706	GGDEF domain
AL552_07300	COG5001	Diguanylate cyclase
AL552_07300	COG2203	Gaf domain
AL552_07300	COG4251	negative regulation of phosphorylation
AL552_07300	COG3706	GGDEF domain
AL552_07310	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL552_07315	COG4149	molybdate abc transporter
AL552_07320	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL552_07340	COG4067	protein conserved in archaea
AL552_07340	COG0189	ligase activity
AL552_07350	COG2207	Transcriptional regulator
AL552_07355	COG0534	Mate efflux family protein
AL552_07360	COG0602	queuosine metabolic process
AL552_07365	COG1328	CTP reductase activity
AL552_07380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL552_07410	COG1794	racemase activity, acting on amino acids and derivatives
AL552_07415	COG0384	phenazine biosynthesis protein PhzF
AL552_07425	COG0243	molybdopterin cofactor binding
AL552_07435	COG0583	DNA-binding transcription factor activity
AL552_07440	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL552_07450	COG2197	response regulator
AL552_07455	COG3851	Histidine kinase
AL552_07460	COG2271	Major facilitator Superfamily
AL552_07490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL552_07495	COG3118	belongs to the thioredoxin family
AL552_07500	COG2814	Major facilitator Superfamily
AL552_07530	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL552_07550	COG2116	formate transmembrane transporter activity
AL552_07555	COG2146	nitrite reductase [NAD(P)H] activity
AL552_07560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL552_07565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL552_07575	COG5001	Diguanylate cyclase
AL552_07650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL552_07665	COG0583	DNA-binding transcription factor activity
AL552_07685	COG0277	FAD linked oxidase domain protein
AL552_07690	COG0583	DNA-binding transcription factor activity
AL552_07705	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL552_07720	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL552_07730	COG1288	antiporter activity
AL552_07740	COG3040	lipid binding
AL552_07750	COG0419	ATPase involved in DNA repair
AL552_07755	COG0420	3'-5' exonuclease activity
AL552_07770	COG3501	Rhs element vgr protein
AL552_07825	COG0631	protein serine/threonine phosphatase activity
AL552_07865	COG0515	serine threonine protein kinase
AL552_07865	COG2815	serine threonine protein kinase
AL552_07915	COG2146	nitrite reductase [NAD(P)H] activity
AL552_07915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL552_07920	COG1116	anion transmembrane transporter activity
AL552_07925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL552_07930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL552_07930	COG1116	anion transmembrane transporter activity
AL552_07950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL552_07970	COG0814	amino acid
AL552_08045	COG2847	Copper chaperone PCu(A)C
AL552_08050	COG0443	Heat shock 70 kDa protein
AL552_08105	COG2885	chlorophyll binding
AL552_08105	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL552_08125	COG4160	amino acid transport
AL552_08130	COG4215	(ABC) transporter
AL552_08135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL552_08140	COG1126	abc transporter atp-binding protein
AL552_08170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL552_08240	COG1475	DNA binding
AL552_08245	COG1192	Involved in chromosome partitioning
AL552_08340	COG0776	regulation of translation
AL552_08375	COG2337	Toxic component of a toxin-antitoxin (TA) module
AL552_08435	COG1278	Cold shock
AL552_08510	COG0745	RESPONSE REGULATOR receiver
AL552_08510	COG3706	GGDEF domain
AL552_08540	COG0675	Transposase, IS605 OrfB family
AL552_08560	COG0701	Predicted permease
AL552_08575	COG1278	Cold shock
AL552_08605	COG1278	Cold shock
AL552_08900	COG1295	ribonuclease BN
AL552_08905	COG1490	D-aminoacyl-tRNA deacylase activity
AL552_08910	COG0456	acetyltransferase
AL552_08920	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AL552_08925	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL552_08930	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL552_08935	COG3031	protein transport across the cell outer membrane
AL552_08945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL552_08950	COG1459	type II secretion system
AL552_08955	COG2165	general secretion pathway protein
AL552_08960	COG2165	general secretion pathway protein
AL552_08965	COG2165	general secretion pathway protein
AL552_08975	COG3156	type II secretion system protein K
AL552_08980	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL552_08985	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL552_08995	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL552_09000	COG0494	nUDIX hydrolase
AL552_09005	COG0316	Belongs to the HesB IscA family
AL552_09005	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AL552_09010	COG1040	competence protein
AL552_09015	COG0596	Alpha beta hydrolase
AL552_09025	COG2183	response to ionizing radiation
AL552_09035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL552_09045	COG0745	RESPONSE REGULATOR receiver
AL552_09050	COG2205	protein histidine kinase activity
AL552_09055	COG2233	PERMEase
AL552_09060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL552_09065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL552_09070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL552_09075	COG1758	RNA polymerase activity
AL552_09080	COG0194	GDP metabolic process
AL552_09095	COG0848	biopolymer transport protein
AL552_09100	COG0811	peptide transport
AL552_09125	COG4174	ABC transporter (Permease)
AL552_09140	COG0444	Belongs to the ABC transporter superfamily
AL552_09145	COG4608	Belongs to the ABC transporter superfamily
AL552_09235	COG1561	YicC-like family, N-terminal region
AL552_09245	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL552_09250	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL552_09255	COG1560	Kdo2-lipid A biosynthetic process
AL552_09260	COG1309	transcriptional regulator
AL552_09265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL552_09280	COG2003	Belongs to the UPF0758 family
AL552_09315	COG0438	transferase activity, transferring glycosyl groups
AL552_09320	COG0463	Glycosyl transferase, family 2
AL552_09325	COG0859	PFAM glycosyl transferase family 9
AL552_09330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL552_09335	COG3642	lipopolysaccharide core region biosynthetic process
AL552_09345	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL552_09370	COG2895	sulfate adenylyltransferase (ATP) activity
AL552_09375	COG0529	Catalyzes the synthesis of activated sulfate
AL552_09380	COG0175	sulfate reduction
AL552_09385	COG3273	potassium ion transport
AL552_09385	COG0471	metal ion transport
AL552_09390	COG1519	Transferase
AL552_09395	COG0859	PFAM glycosyl transferase family 9
AL552_09405	COG1560	Kdo2-lipid A biosynthetic process
AL552_09415	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL552_09445	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL552_09450	COG1459	type II secretion system
AL552_09460	COG1450	Type ii and iii secretion system protein
AL552_09540	COG1215	transferase activity, transferring glycosyl groups
AL552_09545	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL552_09555	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL552_09610	COG0149	triose-phosphate isomerase activity
AL552_09640	COG1494	fructose-1,6-bisphosphatase
AL552_09655	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL552_09660	COG1575	Belongs to the MenA family. Type 1 subfamily
AL552_09665	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL552_09670	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL552_09680	COG1609	Transcriptional regulator
AL552_09685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL552_09695	COG0254	rRNA binding
AL552_09705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL552_09710	COG0088	Forms part of the polypeptide exit tunnel
AL552_09720	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL552_09725	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL552_09730	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL552_09735	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL552_09745	COG0255	Belongs to the universal ribosomal protein uL29 family
AL552_09750	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL552_09760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL552_09765	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL552_09770	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL552_09775	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL552_09780	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL552_09795	COG1841	ribosomal large subunit assembly
AL552_09805	COG0201	protein transport
AL552_09815	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL552_09820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL552_09830	COG0202	RNA polymerase activity
AL552_09835	COG0203	ribosomal protein L17
AL552_09845	COG0545	Peptidyl-prolyl cis-trans isomerase
AL552_09855	COG2153	protein acetylation
AL552_09860	COG0513	Belongs to the DEAD box helicase family
AL552_09870	COG0737	Belongs to the 5'-nucleotidase family
AL552_09880	COG0175	sulfate reduction
AL552_09885	COG2895	sulfate adenylyltransferase (ATP) activity
AL552_09890	COG3273	potassium ion transport
AL552_09890	COG0471	metal ion transport
AL552_09895	COG0529	Catalyzes the synthesis of activated sulfate
AL552_09915	COG4181	ATPase activity
AL552_09930	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL552_09940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL552_09945	COG0729	surface antigen
AL552_09950	COG2911	Protein conserved in bacteria
AL552_09955	COG2105	PFAM AIG2 family protein
AL552_09965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL552_09970	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL552_09980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL552_09985	COG0163	prenyltransferase activity
AL552_09990	COG4143	(ABC) transporter
AL552_09995	COG1178	ABC-type Fe3 transport system permease component
AL552_10000	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AL552_10005	COG0583	DNA-binding transcription factor activity
AL552_10050	COG0142	geranyltranstransferase activity
AL552_10055	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL552_10065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL552_10070	COG2966	Psort location CytoplasmicMembrane, score
AL552_10085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL552_10090	COG2967	ApaG domain
AL552_10095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL552_10100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL552_10105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL552_10110	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL552_10115	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL552_10135	COG0473	3-isopropylmalate dehydrogenase activity
AL552_10140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL552_10165	COG0583	DNA-binding transcription factor activity
AL552_10175	COG0028	Belongs to the TPP enzyme family
AL552_10185	COG3706	GGDEF domain
AL552_10195	COG0469	pyruvate kinase activity
AL552_10205	COG1349	DNA-binding transcription factor activity
AL552_10210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL552_10225	COG5002	protein histidine kinase activity
AL552_10235	COG2376	Dihydroxyacetone kinase
AL552_10240	COG1461	Dihydroxyacetone kinase
AL552_10255	COG3722	fumarate hydratase activity
AL552_10260	COG0246	Mannitol dehydrogenase
AL552_10265	COG2213	PTS system mannitol-specific
AL552_10265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL552_10300	COG1464	Belongs to the NlpA lipoprotein family
AL552_10310	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL552_10315	COG0358	DNA primase activity
AL552_10320	COG1610	YqeY-like protein
AL552_10325	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL552_10330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL552_10335	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL552_10340	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL552_10345	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL552_10350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL552_10355	COG1968	undecaprenyl-diphosphatase activity
AL552_10360	COG0617	tRNA 3'-terminal CCA addition
AL552_10365	COG3267	Type II secretory pathway component ExeA
AL552_10365	COG3409	Peptidoglycan-binding domain 1 protein
AL552_10375	COG0405	Gamma-glutamyltransferase
AL552_10380	COG4991	sh3 domain protein
AL552_10385	COG0306	phosphate transporter
AL552_10390	COG1392	Phosphate transport regulator
AL552_10395	COG3025	triphosphatase activity
AL552_10415	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL552_10415	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL552_10420	COG1538	Outer membrane efflux protein
AL552_10425	COG0494	nUDIX hydrolase
AL552_10430	COG3151	Protein conserved in bacteria
AL552_10440	COG3150	esterase
AL552_10445	COG0187	DNA topoisomerase II activity
AL552_10450	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AL552_10455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL552_10465	COG3105	Protein conserved in bacteria
AL552_10475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL552_10485	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL552_10490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL552_10495	COG0723	plastoquinol--plastocyanin reductase activity
AL552_10500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL552_10505	COG2857	Cytochrome c1
AL552_10510	COG0625	glutathione transferase activity
AL552_10515	COG2969	positive regulation of protein catabolic process
AL552_10520	COG2823	Periplasmic or secreted lipoprotein
AL552_10525	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL552_10540	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL552_10560	COG3116	cell division
AL552_10565	COG0768	penicillin binding
AL552_10570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL552_10575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL552_10580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL552_10585	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL552_10590	COG0772	Belongs to the SEDS family
AL552_10600	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL552_10605	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL552_10610	COG0849	cell division
AL552_10615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL552_10620	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL552_10630	COG0653	protein targeting
AL552_10635	COG0494	nUDIX hydrolase
AL552_10645	COG0505	Belongs to the CarA family
AL552_10650	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL552_10670	COG0730	response to heat
AL552_10685	COG0583	DNA-binding transcription factor activity
AL552_10690	COG2860	membrane
AL552_10705	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL552_10715	COG0493	'glutamate synthase
AL552_10720	COG0069	glutamate synthase activity
AL552_10720	COG0070	glutamate synthase
AL552_10720	COG0067	glutamate synthase
AL552_10730	COG0067	glutamate synthase
AL552_10730	COG0069	glutamate synthase activity
AL552_10730	COG0070	glutamate synthase
AL552_10735	COG1242	4 iron, 4 sulfur cluster binding
AL552_10740	COG5001	Diguanylate cyclase
AL552_10740	COG2203	Gaf domain
AL552_10740	COG3706	GGDEF domain
AL552_10740	COG4251	negative regulation of phosphorylation
AL552_10745	COG2198	Histidine kinase
AL552_10745	COG5002	protein histidine kinase activity
AL552_10745	COG0784	Response regulator, receiver
AL552_10755	COG0745	RESPONSE REGULATOR receiver
AL552_10770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL552_10790	COG0083	homoserine kinase activity
AL552_10795	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL552_10805	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
AL552_10810	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AL552_10820	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL552_10835	COG1115	amino acid carrier protein
AL552_10840	COG3022	response to hydroperoxide
AL552_10845	COG0513	Belongs to the DEAD box helicase family
AL552_10850	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AL552_10860	COG0716	FMN binding
AL552_10870	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL552_10885	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL552_10890	COG2204	response regulator
AL552_10900	COG0667	Aldo Keto reductase
AL552_10920	COG0494	nUDIX hydrolase
AL552_10930	COG0730	response to heat
AL552_10940	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL552_10950	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL552_10955	COG0583	DNA-binding transcription factor activity
AL552_10960	COG0640	Transcriptional regulator
AL552_10965	COG0268	Binds directly to 16S ribosomal RNA
AL552_10970	COG0728	peptidoglycan biosynthetic process
AL552_10975	COG0196	riboflavin kinase activity
AL552_10985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL552_10990	COG1047	Peptidyl-prolyl cis-trans
AL552_10995	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL552_11005	COG3279	Response regulator of the LytR AlgR family
AL552_11010	COG3275	phosphorelay sensor kinase activity
AL552_11015	COG1966	Carbon starvation protein
AL552_11035	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL552_11040	COG1472	Belongs to the glycosyl hydrolase 3 family
AL552_11045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL552_11050	COG1605	Chorismate mutase
AL552_11050	COG0287	Prephenate dehydrogenase
AL552_11055	COG0741	lytic transglycosylase activity
AL552_11055	COG0739	heme binding
AL552_11055	COG1196	nuclear chromosome segregation
AL552_11065	COG0488	(ABC) transporter
AL552_11075	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
AL552_11080	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AL552_11085	COG0077	Prephenate dehydratase
AL552_11085	COG1605	Chorismate mutase
AL552_11090	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL552_11095	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL552_11100	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL552_11105	COG0564	pseudouridine synthase activity
AL552_11115	COG0542	response to heat
AL552_11175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL552_11185	COG2974	May be involved in recombination
AL552_11195	COG0745	RESPONSE REGULATOR receiver
AL552_11200	COG5002	protein histidine kinase activity
AL552_11210	COG0248	Ppx GppA phosphatase
AL552_11215	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL552_11220	COG0573	inorganic phosphate transmembrane transporter activity
AL552_11225	COG0581	inorganic phosphate transmembrane transporter activity
AL552_11230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL552_11235	COG0704	Plays a role in the regulation of phosphate uptake
AL552_11245	COG3142	Participates in the control of copper homeostasis
AL552_11255	COG0450	alkyl hydroperoxide reductase
AL552_11260	COG0583	DNA-binding transcription factor activity
AL552_11265	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL552_11275	COG0517	IMP dehydrogenase activity
AL552_11290	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL552_11300	COG1862	Preprotein translocase
AL552_11305	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL552_11310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL552_11315	COG0483	inositol monophosphate 1-phosphatase activity
AL552_11330	COG1104	cysteine desulfurase activity
AL552_11335	COG0822	iron-sulfur transferase activity
AL552_11350	COG0443	Heat shock 70 kDa protein
AL552_11355	COG0633	Ferredoxin
AL552_11360	COG2975	iron-sulfur cluster assembly
AL552_11370	COG0105	UTP biosynthetic process
AL552_11390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL552_11395	COG0124	histidyl-tRNA synthetase
AL552_11400	COG2976	Protein conserved in bacteria
AL552_11405	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL552_11410	COG1160	GTP binding
AL552_11430	COG0516	GMP reductase activity
AL552_11430	COG0517	IMP dehydrogenase activity
AL552_11435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL552_11435	COG0519	Catalyzes the synthesis of GMP from XMP
AL552_11440	COG1757	Na H antiporter
AL552_11450	COG1584	GPR1 FUN34 yaaH family protein
AL552_11455	COG1115	amino acid carrier protein
AL552_11475	COG2873	o-acetylhomoserine
AL552_11480	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL552_11500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL552_11500	COG3153	acetyltransferase
AL552_11505	COG0583	DNA-binding transcription factor activity
AL552_11530	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL552_11535	COG2867	negative regulation of translational initiation
AL552_11540	COG2914	Belongs to the UPF0125 (RnfH) family
AL552_11545	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL552_11550	COG0497	DNA recombination
AL552_11560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL552_11565	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL552_11570	COG1301	dicarboxylic acid transport
AL552_11580	COG0484	heat shock protein binding
AL552_11610	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL552_11625	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL552_11630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL552_11630	COG0047	phosphoribosylformylglycinamidine synthase activity
AL552_11660	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL552_11665	COG2252	PERMEase
AL552_11670	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL552_11685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL552_11690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL552_11695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL552_11700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL552_11700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL552_11725	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL552_11730	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL552_11735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL552_11740	COG0142	geranyltranstransferase activity
AL552_11745	COG1722	exodeoxyribonuclease VII activity
AL552_11750	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL552_11760	COG0301	tRNA thio-modification
AL552_11760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL552_11765	COG0583	DNA-binding transcription factor activity
AL552_11775	COG2363	Small membrane protein
AL552_11785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL552_11790	COG1611	Belongs to the LOG family
AL552_11805	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL552_11805	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL552_11815	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AL552_11820	COG1464	Belongs to the NlpA lipoprotein family
AL552_11825	COG2011	ABC-type metal ion transport system permease component
AL552_11830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL552_11835	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL552_11845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL552_11845	COG1263	PTS System
AL552_11850	COG0366	Alpha amylase catalytic
AL552_11865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL552_11870	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL552_11880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL552_11885	COG0321	lipoyl(octanoyl) transferase activity
AL552_11895	COG1686	Belongs to the peptidase S11 family
AL552_11900	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL552_11905	COG0772	Belongs to the SEDS family
AL552_11910	COG0768	penicillin binding
AL552_11915	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL552_11920	COG0799	negative regulation of ribosome biogenesis
AL552_11930	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AL552_11935	COG0495	leucyl-tRNA aminoacylation
AL552_11940	COG2888	peptidyl-tyrosine sulfation
AL552_11945	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL552_11950	COG4535	Mg2 and Co2 transporter CorC
AL552_11955	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL552_11960	COG1702	phosphate starvation-inducible protein PhoH
AL552_11965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL552_11975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL552_12085	COG0012	GTP binding
AL552_12090	COG0193	aminoacyl-tRNA hydrolase activity
AL552_12095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL552_12100	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL552_12105	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AL552_12110	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL552_12115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL552_12120	COG2890	protein-(glutamine-N5) methyltransferase activity
AL552_12125	COG3094	Invasion gene expression up-regulator, SirB
AL552_12130	COG2912	Transglutaminase-like superfamily
AL552_12135	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL552_12140	COG0737	Belongs to the 5'-nucleotidase family
AL552_12150	COG1187	pseudouridine synthase activity
AL552_12155	COG2840	Smr protein MutS2
AL552_12195	COG2217	Heavy metal translocating P-type atpase
AL552_12195	COG2608	mercury ion transmembrane transporter activity
AL552_12215	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL552_12270	COG0835	chemotaxis
AL552_12270	COG0784	Response regulator, receiver
AL552_12275	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL552_12280	COG1815	bacterial-type flagellum-dependent cell motility
AL552_12285	COG1558	bacterial-type flagellum-dependent cell motility
AL552_12290	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL552_12295	COG1749	Flagellar hook protein flgE
AL552_12300	COG4787	bacterial-type flagellum-dependent cell motility
AL552_12305	COG4786	Flagellar basal body rod
AL552_12310	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL552_12315	COG1706	bacterial-type flagellum-dependent cell motility
AL552_12320	COG1705	Flagellar rod assembly protein muramidase FlgJ
AL552_12320	COG3951	Flagellar rod assembly protein muramidase FlgJ
AL552_12330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL552_12335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL552_12350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL552_12355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL552_12360	COG2190	(PTS) system
AL552_12365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL552_12370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL552_12380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL552_12385	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AL552_12390	COG3115	cell septum assembly
AL552_12420	COG0330	HflC and HflK could
AL552_12425	COG3118	belongs to the thioredoxin family
AL552_12435	COG0300	oxidoreductase activity
AL552_12440	COG1090	epimerase
AL552_12470	COG0622	Phosphoesterase
AL552_12490	COG3710	Transcriptional regulator
AL552_12495	COG0326	Molecular chaperone. Has ATPase activity
AL552_12505	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL552_12510	COG3104	oligopeptide transport
AL552_12515	COG0250	Participates in transcription elongation, termination and antitermination
AL552_12520	COG0367	asparagine synthase
AL552_12525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL552_12525	COG4651	solute:proton antiporter activity
AL552_12530	COG1846	Transcriptional regulator
AL552_12530	COG1940	carbohydrate kinase activity
AL552_12535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL552_12550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL552_12555	COG0735	belongs to the Fur family
AL552_12565	COG0716	FMN binding
AL552_12575	COG0596	Alpha beta hydrolase
AL552_12580	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AL552_12585	COG0033	Phosphoglucomutase
AL552_12595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL552_12605	COG2009	succinate dehydrogenase
AL552_12610	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL552_12615	COG1053	succinate dehydrogenase
AL552_12620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL552_12625	COG0567	Dehydrogenase, E1 component
AL552_12630	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL552_12645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL552_12655	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL552_12660	COG4977	sequence-specific DNA binding
AL552_12670	COG1918	ferrous iron import across plasma membrane
AL552_12690	COG0018	arginyl-trna synthetase
AL552_12700	COG3102	Protein conserved in bacteria
AL552_12705	COG0788	formyltetrahydrofolate deformylase activity
AL552_12715	COG1214	PFAM Peptidase M22, glycoprotease
AL552_12730	COG2267	carboxylic ester hydrolase activity
AL552_12740	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL552_12745	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL552_12750	COG2894	cell division
AL552_12755	COG0850	regulation of cytokinetic process
AL552_12760	COG3100	YcgL domain-containing protein
AL552_12765	COG2951	lytic endotransglycosylase activity
AL552_12775	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL552_12780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL552_12790	COG2226	methyltransferase
AL552_12800	COG1028	Short-chain dehydrogenase reductase Sdr
AL552_12805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL552_12810	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL552_12835	COG2986	histidine ammonia-lyase
AL552_12840	COG1216	Glycosyl transferase, family 2
AL552_12845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL552_12860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL552_12865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL552_12900	COG1253	flavin adenine dinucleotide binding
AL552_12905	COG0513	Belongs to the DEAD box helicase family
AL552_12910	COG0569	domain protein
AL552_12915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL552_12930	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AL552_12935	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL552_12940	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL552_12945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL552_12970	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL552_12980	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL552_12985	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL552_12990	COG0776	regulation of translation
AL552_12995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL552_13000	COG1555	photosystem II stabilization
AL552_13015	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL552_13020	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AL552_13025	COG0436	Aminotransferase
AL552_13030	COG1169	isochorismate synthase
AL552_13035	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AL552_13040	COG0596	Alpha beta hydrolase
AL552_13045	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL552_13050	COG1441	menaquinone biosynthetic process
AL552_13065	COG2855	membrane
AL552_13070	COG0477	Major facilitator Superfamily
AL552_13120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL552_13125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL552_13150	COG1522	sequence-specific DNA binding
AL552_13160	COG1946	Acyl-CoA thioesterase
AL552_13165	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL552_13180	COG0745	RESPONSE REGULATOR receiver
AL552_13180	COG3706	GGDEF domain
AL552_13190	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL552_13195	COG0517	IMP dehydrogenase activity
AL552_13195	COG0516	GMP reductase activity
AL552_13225	COG0537	adenosine 5'-monophosphoramidase activity
AL552_13250	COG3150	esterase
AL552_13255	COG1252	NADH dehydrogenase
AL552_13270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL552_13280	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL552_13285	COG1136	(ABC) transporter
AL552_13290	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL552_13300	COG2333	competence protein COMEC
AL552_13300	COG0658	competence protein
AL552_13305	COG1132	(ABC) transporter
AL552_13325	COG2719	SpoVR family
AL552_13330	COG2718	Belongs to the UPF0229 family
AL552_13335	COG2766	serine protein kinase
AL552_13345	COG3013	Belongs to the UPF0304 family
AL552_13355	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL552_13365	COG1882	Formate acetyltransferase
AL552_13395	COG4215	(ABC) transporter
AL552_13410	COG0708	Exodeoxyribonuclease III
AL552_13420	COG3923	Primosomal replication protein n
AL552_13425	COG0730	response to heat
AL552_13440	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL552_13445	COG1187	pseudouridine synthase activity
AL552_13455	COG1278	Cold shock
AL552_13460	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL552_13465	COG0542	response to heat
AL552_13470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL552_13475	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL552_13500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL552_13505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL552_13510	COG0297	glycogen (starch) synthase activity
AL552_13530	COG3070	regulator of competence-specific genes
AL552_13535	COG1609	Transcriptional regulator
AL552_13540	COG3381	protein complex oligomerization
AL552_13545	COG0745	RESPONSE REGULATOR receiver
AL552_13550	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL552_13555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL552_13560	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AL552_13565	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AL552_13570	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL552_13590	COG4067	protein conserved in archaea
AL552_13590	COG0189	ligase activity
AL552_13600	COG0500	methyltransferase
AL552_13610	COG1801	Protein of unknown function DUF72
AL552_13620	COG0217	transcriptional regulatory protein
AL552_13625	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AL552_13630	COG0632	four-way junction helicase activity
AL552_13635	COG2255	four-way junction helicase activity
AL552_13640	COG1271	oxidase subunit
AL552_13645	COG1294	oxidase, subunit
AL552_13650	COG4890	Cyd operon protein YbgT
AL552_13660	COG0824	Thioesterase
AL552_13665	COG0811	peptide transport
AL552_13680	COG0823	Involved in the tonB-independent uptake of proteins
AL552_13685	COG2885	chlorophyll binding
AL552_13690	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL552_13695	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL552_13705	COG3766	membrane
AL552_13725	COG0784	Response regulator, receiver
AL552_13725	COG5002	protein histidine kinase activity
AL552_13740	COG0840	transmembrane signaling receptor activity
AL552_13745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL552_13750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL552_13775	COG3568	Endonuclease Exonuclease Phosphatase
AL552_13785	COG0840	transmembrane signaling receptor activity
AL552_13800	COG0583	DNA-binding transcription factor activity
AL552_13810	COG0686	Belongs to the AlaDH PNT family
AL552_13820	COG1674	ftsk spoiiie
AL552_13825	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL552_13830	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL552_13835	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL552_13865	COG1073	alpha beta
AL552_13865	COG2226	methyltransferase
AL552_13870	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL552_13890	COG0300	oxidoreductase activity
AL552_13905	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL552_13915	COG2268	Band 7 protein
AL552_13925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL552_13930	COG2915	High frequency lysogenization protein hflD homolog
AL552_13935	COG0482	sulfurtransferase activity
AL552_13945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL552_13955	COG1757	Na H antiporter
AL552_13965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL552_13970	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL552_13975	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL552_13980	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL552_13980	COG0131	Imidazoleglycerol-phosphate dehydratase
AL552_13985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL552_13990	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL552_13995	COG0107	imidazoleglycerol-phosphate synthase activity
AL552_14000	COG0140	phosphoribosyl-ATP diphosphatase activity
AL552_14000	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL552_14005	COG3012	SEC-C Motif Domain Protein
AL552_14010	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL552_14015	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL552_14020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL552_14025	COG0215	cysteine-tRNA ligase activity
AL552_14030	COG1435	thymidine kinase activity
AL552_14035	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL552_14060	COG2116	formate transmembrane transporter activity
AL552_14070	COG0390	transport system, permease component
AL552_14075	COG4459	periplasmic nitrate reductase
AL552_14080	COG3005	denitrification pathway
AL552_14085	COG0243	molybdopterin cofactor binding
AL552_14100	COG1227	inorganic diphosphatase activity
AL552_14110	COG4172	Belongs to the ABC transporter superfamily
AL552_14120	COG4171	peptide transport system, permease
AL552_14125	COG4168	peptide transport system, permease
AL552_14135	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL552_14140	COG1842	Phage shock protein A
AL552_14150	COG1983	PspC domain protein
AL552_14170	COG2818	Glycosylase
AL552_14175	COG5380	lipid catabolic process
AL552_14180	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AL552_14185	COG0626	cystathionine gamma-synthase activity
AL552_14195	COG0733	neurotransmitter:sodium symporter activity
AL552_14200	COG0564	pseudouridine synthase activity
AL552_14210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL552_14215	COG1151	hydroxylamine reductase activity
AL552_14220	COG3604	Transcriptional regulator
AL552_14235	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL552_14240	COG4136	ATPase activity
AL552_14245	COG4135	transport system, permease component
AL552_14250	COG4134	Bacterial extracellular solute-binding protein
AL552_14260	COG3313	Fe-S protein
AL552_14280	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL552_14290	COG2205	protein histidine kinase activity
AL552_14295	COG0745	RESPONSE REGULATOR receiver
AL552_14305	COG1061	Type III restriction enzyme res subunit
AL552_14310	COG1187	pseudouridine synthase activity
AL552_14320	COG2814	Major facilitator Superfamily
AL552_14350	COG3005	denitrification pathway
AL552_14355	COG0702	epimerase
AL552_14360	COG0534	Mate efflux family protein
AL552_14380	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL552_14390	COG1960	acyl-CoA dehydrogenase activity
AL552_14395	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL552_14400	COG2985	domain, Protein
AL552_14400	COG3273	potassium ion transport
AL552_14405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL552_14425	COG1737	Transcriptional regulator
AL552_14430	COG0076	glutamate decarboxylase activity
AL552_14440	COG2431	L-lysine efflux transmembrane transporter activity
AL552_14455	COG3070	regulator of competence-specific genes
AL552_14470	COG4191	Histidine kinase
AL552_14470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL552_14480	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL552_14490	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL552_14495	COG4988	ABC transporter
AL552_14500	COG0492	ferredoxin-NADP+ reductase activity
AL552_14525	COG0471	metal ion transport
AL552_14530	COG2949	membrane
AL552_14535	COG0281	malic enzyme
AL552_14555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL552_14590	COG0277	FAD linked oxidase domain protein
AL552_14590	COG0247	lactate metabolic process
AL552_14605	COG2986	histidine ammonia-lyase
AL552_14610	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AL552_14615	COG0010	Belongs to the arginase family
AL552_14620	COG1228	amidohydrolase
AL552_14625	COG2188	Transcriptional regulator
AL552_14640	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL552_14650	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL552_14660	COG0393	Putative heavy-metal-binding
AL552_14690	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL552_14695	COG0072	phenylalanine-tRNA ligase activity
AL552_14695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL552_14705	COG0776	regulation of translation
AL552_14715	COG0500	methyltransferase
AL552_14720	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL552_14725	COG0295	cytidine deaminase activity
AL552_14730	COG1346	cytolysis
AL552_14735	COG1380	Effector of murein hydrolase LrgA
AL552_14740	COG2925	Exonuclease
AL552_14750	COG0702	epimerase
AL552_14755	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AL552_14760	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AL552_14780	COG2988	succinylglutamate desuccinylase activity
AL552_14785	COG4139	cobalamin transport
AL552_14790	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AL552_14810	COG0583	DNA-binding transcription factor activity
AL552_14820	COG1451	nucleotide metabolic process
AL552_14825	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AL552_14855	COG3938	Belongs to the proline racemase family
AL552_14870	COG2423	ornithine cyclodeaminase activity
AL552_14875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL552_14880	COG3842	ATPase activity
AL552_14890	COG1177	transmembrane transport
AL552_14900	COG3291	Pkd domain containing protein
AL552_14920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL552_14925	COG0601	transmembrane transport
AL552_14935	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL552_14945	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL552_14955	COG0625	glutathione transferase activity
AL552_14990	COG2200	EAL domain
AL552_15000	COG1846	Transcriptional regulator
AL552_15005	COG2315	Protein conserved in bacteria
AL552_15020	COG0110	maltose O-acetyltransferase activity
AL552_15050	COG3063	Type IV pilus biogenesis stability protein PilW
AL552_15055	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AL552_15070	COG0531	amino acid
AL552_15075	COG1560	Kdo2-lipid A biosynthetic process
AL552_15080	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL552_15085	COG1280	lysine exporter protein (LysE YggA)
AL552_15095	COG1115	amino acid carrier protein
AL552_15125	COG1368	sulfuric ester hydrolase activity
AL552_15130	COG0642	Histidine kinase
AL552_15135	COG0745	RESPONSE REGULATOR receiver
AL552_15145	COG1028	Short-chain dehydrogenase reductase Sdr
AL552_15155	COG1022	Amp-dependent synthetase and ligase
AL552_15165	COG2113	Glycine betaine
AL552_15170	COG4176	ABC-type proline glycine betaine transport system permease component
AL552_15190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL552_15195	COG0456	acetyltransferase
AL552_15200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL552_15205	COG0662	Cupin 2, conserved barrel domain protein
AL552_15210	COG0527	aspartate kinase activity
AL552_15230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL552_15245	COG3290	protein histidine kinase activity
AL552_15250	COG4565	transcriptional regulatory protein
AL552_15260	COG4977	sequence-specific DNA binding
AL552_15265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL552_15270	COG0363	glucosamine-6-phosphate deaminase activity
AL552_15275	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL552_15300	COG3284	Transcriptional regulator
AL552_15305	COG1012	belongs to the aldehyde dehydrogenase family
AL552_15375	COG4669	(LipO)protein
AL552_15395	COG3177	Filamentation induced by cAMP protein fic
AL552_15425	COG1028	Short-chain dehydrogenase reductase Sdr
AL552_15450	COG4792	protein secretion
AL552_15455	COG4791	protein targeting
AL552_15460	COG4794	Type iii secretion
AL552_15465	COG4790	Type iii secretion
AL552_15535	COG0457	Tetratricopeptide repeat
AL552_15560	COG0730	response to heat
AL552_15595	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AL552_15600	COG0372	Belongs to the citrate synthase family
AL552_15610	COG2828	Protein conserved in bacteria
AL552_15635	COG0561	phosphatase activity
AL552_15640	COG0602	queuosine metabolic process
AL552_15645	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL552_15650	COG3706	GGDEF domain
AL552_15710	COG1254	Belongs to the acylphosphatase family
AL552_15715	COG2920	part of a sulfur-relay system
AL552_15730	COG0670	Belongs to the BI1 family
AL552_15735	COG1126	abc transporter atp-binding protein
AL552_15740	COG0765	amino acid transport
AL552_15745	COG4597	amino acid ABC transporter
AL552_15750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL552_15765	COG1666	GTP binding
AL552_15770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL552_15795	COG3008	intermembrane lipid transfer
AL552_15800	COG2995	paraquat-inducible protein a
AL552_15805	COG1132	(ABC) transporter
AL552_15810	COG1956	GAF domain-containing protein
AL552_15815	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AL552_15830	COG0308	aminopeptidase N
AL552_15845	COG0167	dihydroorotate dehydrogenase activity
AL552_15855	COG0116	Belongs to the methyltransferase superfamily
AL552_15855	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL552_15880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL552_15885	COG1067	ATP-dependent peptidase activity
AL552_15890	COG3120	sequence-specific DNA binding
AL552_15910	COG0784	Response regulator, receiver
AL552_15910	COG2205	protein histidine kinase activity
AL552_15925	COG3278	Belongs to the heme-copper respiratory oxidase family
AL552_15940	COG2010	Cytochrome c
AL552_15950	COG2217	Heavy metal translocating P-type atpase
AL552_15965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL552_15970	COG0589	response to stress
AL552_15995	COG3842	ATPase activity
AL552_16000	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL552_16005	COG1177	transmembrane transport
AL552_16010	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL552_16015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL552_16020	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL552_16025	COG0004	ammonium transporteR
AL552_16045	COG4282	regulation of fungal-type cell wall biogenesis
AL552_16185	COG0437	4 iron, 4 sulfur cluster binding
AL552_16190	COG0243	molybdopterin cofactor binding
AL552_16190	COG3383	formate dehydrogenase (NAD+) activity
AL552_16200	COG3381	protein complex oligomerization
AL552_16220	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL552_16225	COG0488	(ABC) transporter
AL552_16235	COG4191	Histidine kinase
AL552_16240	COG2204	response regulator
AL552_16255	COG3842	ATPase activity
AL552_16260	COG0746	molybdenum cofactor guanylyltransferase activity
AL552_16275	COG1940	carbohydrate kinase activity
AL552_16315	COG0791	NLP P60 protein
AL552_16325	COG3706	GGDEF domain
AL552_16345	COG0307	riboflavin synthase, alpha
AL552_16350	COG0534	Mate efflux family protein
AL552_16360	COG1793	dna ligase
AL552_16400	COG0438	transferase activity, transferring glycosyl groups
AL552_16430	COG0438	transferase activity, transferring glycosyl groups
AL552_16435	COG1215	transferase activity, transferring glycosyl groups
AL552_16440	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL552_16450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL552_16465	COG1643	Atp-dependent helicase
AL552_16470	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL552_16515	COG0443	Heat shock 70 kDa protein
AL552_16520	COG0443	Heat shock 70 kDa protein
AL552_16540	COG4968	Prepilin-type N-terminal cleavage methylation domain
AL552_16545	COG1132	(ABC) transporter
AL552_16550	COG1132	(ABC) transporter
AL552_16560	COG4774	siderophore transport
AL552_16570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL552_16575	COG1120	ATPase activity
AL552_16590	COG0814	amino acid
AL552_16600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL552_16610	COG0861	Integral membrane protein TerC family
AL552_16620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL552_16625	COG1328	CTP reductase activity
AL552_16650	COG4191	Histidine kinase
AL552_16675	COG0745	RESPONSE REGULATOR receiver
AL552_16675	COG3706	GGDEF domain
AL552_16680	COG4702	Belongs to the UPF0303 family
AL552_16685	COG0673	inositol 2-dehydrogenase activity
AL552_16690	COG1349	DNA-binding transcription factor activity
AL552_16705	COG0641	radical SAM
AL552_16720	COG3119	arylsulfatase activity
AL552_16725	COG1566	PFAM secretion protein HlyD family protein
AL552_16735	COG0583	DNA-binding transcription factor activity
AL552_16760	COG1280	lysine exporter protein (LysE YggA)
AL552_16770	COG5507	3-demethylubiquinone-9 3-methyltransferase
AL552_16815	COG2801	Transposase and inactivated derivatives
AL552_17200	COG1051	belongs to the nudix hydrolase family
AL552_17315	COG2026	Addiction module toxin, RelE StbE family
AL552_17490	COG1051	belongs to the nudix hydrolase family
AL552_17570	COG1683	Conserved Protein
AL552_17580	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL552_18050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL552_18060	COG3768	UPF0283 membrane protein
AL552_18065	COG3106	COG3106 Predicted ATPase
AL552_18085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL552_18090	COG2205	protein histidine kinase activity
AL552_18090	COG0784	Response regulator, receiver
AL552_18100	COG0494	nUDIX hydrolase
AL552_18105	COG0814	amino acid
AL552_18110	COG1760	l-serine dehydratase
AL552_18115	COG2200	EAL domain
AL552_18125	COG0720	synthase
AL552_18130	COG0840	transmembrane signaling receptor activity
AL552_18135	COG0017	Asparaginyl-tRNA synthetase
AL552_18145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL552_18160	COG1448	Aminotransferase
AL552_18180	COG0840	transmembrane signaling receptor activity
AL552_18185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL552_18215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL552_18230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL552_18235	COG3108	Peptidase M15
AL552_18240	COG2989	Protein conserved in bacteria
AL552_18265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL552_18275	COG4235	cytochrome complex assembly
AL552_18275	COG3088	subunit of a heme lyase
AL552_18285	COG1138	Cytochrome C-type biogenesis protein
AL552_18290	COG3301	Polysulphide reductase, NrfD
AL552_18295	COG0437	4 iron, 4 sulfur cluster binding
AL552_18305	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AL552_18325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL552_18330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL552_18335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL552_18360	COG0019	diaminopimelate decarboxylase activity
AL552_18400	COG0322	excinuclease ABC activity
AL552_18405	COG2197	response regulator
AL552_18410	COG0417	DNA replication proofreading
AL552_18430	COG1187	pseudouridine synthase activity
AL552_18440	COG0009	L-threonylcarbamoyladenylate synthase
AL552_18445	COG0613	PHP domain protein
AL552_18455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL552_18460	COG0512	Glutamine amidotransferase of anthranilate synthase
AL552_18470	COG0135	phosphoribosylanthranilate isomerase activity
AL552_18470	COG0134	indole-3-glycerol-phosphate synthase activity
AL552_18480	COG0159	tryptophan synthase activity
AL552_18485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL552_18490	COG0318	PFAM AMP-dependent synthetase and ligase
AL552_18500	COG1301	dicarboxylic acid transport
AL552_18520	COG2917	probably involved in intracellular septation
AL552_18525	COG1607	acyl-coa hydrolase
AL552_18530	COG2350	Protein conserved in bacteria
AL552_18540	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL552_18560	COG5001	Diguanylate cyclase
AL552_18565	COG1032	radical SAM domain protein
AL552_18570	COG0840	transmembrane signaling receptor activity
AL552_18580	COG0745	RESPONSE REGULATOR receiver
AL552_18585	COG3850	Histidine kinase
AL552_18585	COG5002	protein histidine kinase activity
AL552_18615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL552_18635	COG0577	efflux transmembrane transporter activity
AL552_18635	COG1136	(ABC) transporter
AL552_18640	COG0577	efflux transmembrane transporter activity
AL552_18640	COG1136	(ABC) transporter
AL552_18645	COG1136	(ABC) transporter
AL552_18645	COG0577	efflux transmembrane transporter activity
AL552_18655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL552_18685	COG3118	belongs to the thioredoxin family
AL552_18690	COG4232	protein-disulfide reductase activity
AL552_18725	COG2863	cytochrome
AL552_18730	COG3258	Cytochrome c
AL552_18735	COG2995	paraquat-inducible protein a
AL552_18740	COG3008	intermembrane lipid transfer
AL552_18740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL552_18755	COG4166	transmembrane transport
AL552_18765	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL552_18770	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL552_18780	COG0539	negative regulation of cytoplasmic translation
AL552_18785	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL552_18790	COG0616	signal peptide processing
AL552_18795	COG1028	Short-chain dehydrogenase reductase Sdr
AL552_18810	COG0587	DNA-directed DNA polymerase activity
AL552_18815	COG0835	chemotaxis
AL552_18815	COG0784	Response regulator, receiver
AL552_18820	COG1940	carbohydrate kinase activity
AL552_18825	COG0469	pyruvate kinase activity
AL552_18830	COG4667	esterase of the alpha-beta hydrolase superfamily
AL552_18845	COG0733	neurotransmitter:sodium symporter activity
AL552_18855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL552_18855	COG1263	PTS System
AL552_18860	COG0084	hydrolase, TatD family'
AL552_18865	COG0470	DNA polymerase III
AL552_18870	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL552_18875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL552_18905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL552_18910	COG0416	fatty acid biosynthetic process
AL552_18920	COG1399	metal-binding, possibly nucleic acid-binding protein
AL552_18925	COG0424	maF-like protein
AL552_18930	COG0564	pseudouridine synthase activity
AL552_18935	COG1530	ribonuclease E activity
AL552_18945	COG0659	secondary active sulfate transmembrane transporter activity
AL552_18950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL552_18955	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AL552_18965	COG0572	uridine kinase
AL552_18975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL552_18975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL552_19000	COG2186	Transcriptional regulator
AL552_19005	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL552_19010	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL552_19015	COG0653	protein targeting
AL552_19020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL552_19025	COG3706	GGDEF domain
AL552_19030	COG0366	Alpha amylase catalytic
AL552_19035	COG1122	ATPase activity
AL552_19040	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL552_19050	COG3092	negative regulation of chromosome organization
AL552_19055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL552_19065	COG3174	membrane
AL552_19075	COG0435	Glutathione S-transferase
AL552_19085	COG0444	Belongs to the ABC transporter superfamily
AL552_19090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL552_19095	COG0601	transmembrane transport
AL552_19105	COG0314	molybdopterin synthase activity
AL552_19110	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL552_19115	COG0315	cyclic pyranopterin monophosphate synthase activity
AL552_19120	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL552_19125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL552_19130	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AL552_19135	COG2198	Histidine kinase
AL552_19140	COG2204	response regulator
AL552_19145	COG0556	nucleotide-excision repair
AL552_19155	COG4657	Part of a membrane complex involved in electron transport
AL552_19160	COG2878	Part of a membrane complex involved in electron transport
AL552_19165	COG4656	Part of a membrane complex involved in electron transport
AL552_19170	COG4658	electron transport chain
AL552_19175	COG4659	FMN binding
AL552_19180	COG4660	Part of a membrane complex involved in electron transport
AL552_19185	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL552_19190	COG0346	lactoylglutathione lyase activity
AL552_19200	COG2885	chlorophyll binding
AL552_19210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL552_19215	COG2056	Na+-H+ antiporter family
AL552_19225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL552_19245	COG1012	belongs to the aldehyde dehydrogenase family
AL552_19245	COG1454	alcohol dehydrogenase
AL552_19250	COG2095	MarC family integral membrane protein
AL552_19255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL552_19260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL552_19265	COG1757	Na H antiporter
AL552_19280	COG3081	Nucleoid-associated protein
AL552_19285	COG3082	Protein of unknown function (DUF1414)
AL552_19300	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL552_19315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL552_19320	COG0778	Nitroreductase
AL552_19330	COG1902	pentaerythritol trinitrate reductase activity
AL552_19330	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL552_19335	COG0616	signal peptide processing
AL552_19340	COG0252	asparaginase activity
AL552_19345	COG3139	Protein of unknown function (DUF1315)
AL552_19355	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL552_19360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL552_19375	COG2226	methyltransferase
AL552_19395	COG1785	Belongs to the alkaline phosphatase family
AL552_19405	COG0346	lactoylglutathione lyase activity
AL552_19410	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL552_19415	COG0668	transmembrane transport
AL552_19420	COG2983	Belongs to the UPF0260 family
AL552_19425	COG2261	transglycosylase associated protein
AL552_19440	COG3681	Belongs to the UPF0597 family
AL552_19445	COG0251	oxidation-reduction process
AL552_19450	COG0814	amino acid
AL552_19455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL552_19460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL552_19465	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AL552_19475	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL552_19490	COG0745	RESPONSE REGULATOR receiver
AL552_19495	COG0583	DNA-binding transcription factor activity
AL552_19500	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL552_19505	COG1286	toxin biosynthetic process
AL552_19510	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL552_19515	COG0285	dihydrofolate synthase activity
AL552_19520	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL552_19530	COG0101	tRNA pseudouridine synthase activity
AL552_19540	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL552_19545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL552_19550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL552_19555	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL552_19555	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL552_19560	COG0431	NADPH-dependent FMN reductase
AL552_19575	COG3101	peptidyl-lysine hydroxylation
AL552_19585	COG2860	membrane
AL552_19590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL552_19595	COG2890	protein-(glutamine-N5) methyltransferase activity
AL552_19600	COG2840	Smr protein MutS2
AL552_19605	COG2062	phosphohistidine phosphatase, SixA
AL552_19620	COG1024	Enoyl-CoA hydratase
AL552_19620	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL552_19625	COG0183	Belongs to the thiolase family
AL552_19640	COG2067	long-chain fatty acid transport protein
AL552_19645	COG2067	long-chain fatty acid transport protein
AL552_19655	COG3088	subunit of a heme lyase
AL552_19655	COG4235	cytochrome complex assembly
AL552_19665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL552_19670	COG1138	Cytochrome C-type biogenesis protein
AL552_19675	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL552_19680	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL552_19685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL552_19690	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL552_19695	COG4133	protoheme IX ABC transporter activity
AL552_19705	COG0835	chemotaxis
AL552_19715	COG1192	Involved in chromosome partitioning
AL552_19720	COG2201	protein-glutamate methylesterase activity
AL552_19725	COG0643	Histidine kinase
AL552_19725	COG2198	Histidine kinase
AL552_19730	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL552_19745	COG0455	bacterial-type flagellum organization
AL552_19770	COG1987	bacterial-type flagellum assembly
AL552_19820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL552_19830	COG1677	Flagellar hook-basal body complex protein FliE
AL552_19835	COG2204	response regulator
AL552_19840	COG4191	Histidine kinase
AL552_19850	COG1516	flagellar protein fliS
AL552_19860	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL552_19865	COG1334	flagellar protein FlaG
AL552_19870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL552_19875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL552_19885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL552_19890	COG2837	iron assimilation
AL552_19915	COG1393	Belongs to the ArsC family
AL552_19920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL552_19940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL552_19950	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL552_19965	COG4783	chaperone-mediated protein folding
AL552_19970	COG1393	Belongs to the ArsC family
AL552_19990	COG2233	PERMEase
AL552_19995	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL552_20000	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL552_20005	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL552_20010	COG0121	glutamine amidotransferase
AL552_20015	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL552_20020	COG1960	acyl-CoA dehydrogenase activity
AL552_20050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL552_20055	COG0328	RNA-DNA hybrid ribonuclease activity
AL552_20060	COG2226	methyltransferase
AL552_20065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL552_20070	COG0741	lytic transglycosylase activity
AL552_20070	COG1388	LysM domain
AL552_20080	COG3021	interspecies interaction between organisms
AL552_20085	COG0347	Belongs to the P(II) protein family
AL552_20100	COG0825	malonyl-CoA metabolic process
AL552_20105	COG0587	DNA-directed DNA polymerase activity
AL552_20115	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL552_20120	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL552_20130	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL552_20135	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL552_20145	COG0750	zinc metalloprotease
AL552_20150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL552_20155	COG0575	Belongs to the CDS family
AL552_20160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL552_20165	COG0233	cytoplasmic translational termination
AL552_20170	COG0528	UMP kinase activity
AL552_20175	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL552_20180	COG0052	Belongs to the universal ribosomal protein uS2 family
AL552_20185	COG0024	Methionine aminopeptidase
AL552_20200	COG0564	pseudouridine synthase activity
AL552_20235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL552_20240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL552_20265	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL552_20275	COG0254	rRNA binding
AL552_20280	COG1720	tRNA m6t6A37 methyltransferase activity
AL552_20285	COG0442	prolyl-tRNA aminoacylation
AL552_20305	COG0733	neurotransmitter:sodium symporter activity
AL552_20320	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL552_20325	COG0514	ATP-dependent DNA helicase (RecQ)
AL552_20345	COG1477	protein flavinylation
AL552_20350	COG2871	sodium ion transport
AL552_20355	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL552_20360	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL552_20365	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL552_20370	COG1805	sodium ion transport
AL552_20375	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL552_20385	COG0271	Belongs to the BolA IbaG family
AL552_20390	COG2813	Specifically methylates the guanine in position
AL552_20395	COG3056	Lipoprotein
AL552_20415	COG1595	DNA-templated transcription, initiation
AL552_20440	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL552_20445	COG0693	protein deglycase activity
AL552_20450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL552_20455	COG3706	GGDEF domain
AL552_20460	COG2166	iron-sulfur cluster assembly
AL552_20465	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL552_20470	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL552_20485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL552_20485	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL552_20505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL552_20510	COG1074	ATP-dependent DNA helicase activity
AL552_20520	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL552_20540	COG3141	response to X-ray
AL552_20545	COG2171	N-acyltransferase activity
AL552_20550	COG0584	glycerophosphoryl diester phosphodiesterase
AL552_20555	COG2271	Major facilitator Superfamily
AL552_20565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL552_20570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL552_20575	COG1349	DNA-binding transcription factor activity
AL552_20580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL552_20600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL552_20605	COG1609	Transcriptional regulator
AL552_20610	COG2176	DNA-directed DNA polymerase activity
AL552_20625	COG2017	converts alpha-aldose to the beta-anomer
AL552_20630	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AL552_20635	COG1085	galactose-1-phosphate uridylyltransferase
AL552_20640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL552_20650	COG1609	Transcriptional regulator
AL552_20655	COG3250	beta-galactosidase activity
AL552_20660	COG2731	YhcH YjgK YiaL family protein
AL552_20665	COG0531	amino acid
AL552_20670	COG0583	DNA-binding transcription factor activity
AL552_20730	COG4964	Belongs to the GSP D family
AL552_20755	COG2169	Transcriptional regulator
AL552_20760	COG1022	Amp-dependent synthetase and ligase
AL552_20775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL552_20780	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AL552_20790	COG0560	Phosphoserine phosphatase
AL552_20800	COG0813	purine-nucleoside phosphorylase activity
AL552_20805	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AL552_20810	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AL552_20825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL552_20830	COG0084	hydrolase, TatD family'
AL552_20840	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL552_20860	COG3153	acetyltransferase
AL552_20905	COG1185	polyribonucleotide nucleotidyltransferase activity
AL552_20910	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL552_20915	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL552_20920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL552_20925	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL552_20930	COG0195	Participates in both transcription termination and antitermination
AL552_20935	COG0779	Required for maturation of 30S ribosomal subunits
AL552_20950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL552_20960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL552_20965	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL552_20970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL552_20975	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL552_20980	COG1534	Rna-binding protein
AL552_20985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL552_20990	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL552_20995	COG2027	D-alanyl-D-alanine carboxypeptidase
AL552_21005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL552_21030	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL552_21035	COG0628	permease
AL552_21040	COG2813	Specifically methylates the guanine in position
AL552_21050	COG0747	negative chemotaxis
AL552_21065	COG0444	Belongs to the ABC transporter superfamily
AL552_21070	COG4608	Belongs to the ABC transporter superfamily
AL552_21080	COG2971	BadF BadG BcrA BcrD
AL552_21095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL552_21100	COG3842	ATPase activity
AL552_21110	COG1840	ABC-type Fe3 transport system, periplasmic component
AL552_21115	COG0004	ammonium transporteR
AL552_21120	COG0347	Belongs to the P(II) protein family
AL552_21125	COG3112	Uncharacterised protein family (UPF0231)
AL552_21130	COG1049	propionate catabolic process, 2-methylcitrate cycle
AL552_21135	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL552_21140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL552_21145	COG1643	Atp-dependent helicase
AL552_21150	COG1489	DNA binding
AL552_21155	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL552_21160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL552_21170	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL552_21175	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL552_21180	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL552_21185	COG1560	Kdo2-lipid A biosynthetic process
AL552_21195	COG0842	Transport permease protein
AL552_21200	COG1131	(ABC) transporter
AL552_21205	COG0659	secondary active sulfate transmembrane transporter activity
AL552_21210	COG0288	reversible hydration of carbon dioxide
AL552_21225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL552_21230	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL552_21235	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL552_21240	COG2186	Transcriptional regulator
AL552_21260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL552_21265	COG1459	type II secretion system
AL552_21275	COG0237	dephospho-CoA kinase activity
AL552_21280	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL552_21285	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AL552_21300	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL552_21305	COG0228	four-way junction DNA binding
AL552_21310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL552_21315	COG4137	Cytochrome C assembly protein
AL552_21320	COG4536	flavin adenine dinucleotide binding
AL552_21325	COG1854	S-ribosylhomocysteine lyase activity
AL552_21340	COG0612	Peptidase, M16
AL552_21345	COG1238	metal cluster binding
AL552_21355	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AL552_21360	COG5016	pyruvate
AL552_21360	COG0511	ligase activity, forming carbon-carbon bonds
AL552_21430	COG0527	aspartate kinase activity
AL552_21435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL552_21440	COG2137	regulation of response to DNA damage stimulus
AL552_21445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL552_21455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL552_21460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL552_21470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL552_21475	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL552_21485	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL552_21490	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL552_21495	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL552_21500	COG0148	phosphopyruvate hydratase activity
AL552_21505	COG0504	CTP synthase activity
AL552_21510	COG3956	TIGRFAM MazG family protein
AL552_21515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL552_21525	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL552_21540	COG0736	holo-[acyl-carrier-protein] synthase activity
AL552_21545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL552_21550	COG1381	Involved in DNA repair and RecF pathway recombination
AL552_21555	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL552_21565	COG0681	Belongs to the peptidase S26 family
AL552_21570	COG0481	GTPase activity
AL552_21575	COG3086	response to oxidative stress
AL552_21590	COG1595	DNA-templated transcription, initiation
AL552_21600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL552_21610	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL552_21615	COG0354	folic acid binding
AL552_21630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL552_21635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL552_21640	COG3079	Belongs to the UPF0149 family
AL552_21650	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AL552_21660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL552_21665	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AL552_21670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL552_21680	COG0583	DNA-binding transcription factor activity
AL552_21695	COG0668	transmembrane transport
AL552_21700	COG0191	fructose-bisphosphate aldolase activity
AL552_21705	COG0126	phosphoglycerate kinase activity
AL552_21710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL552_21715	COG4771	TonB-dependent receptor
AL552_21720	COG0583	DNA-binding transcription factor activity
AL552_21725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL552_21735	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL552_21750	COG2356	endonuclease I
AL552_21755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL552_21760	COG0189	ligase activity
AL552_21765	COG1678	Uncharacterized ACR, COG1678
AL552_21770	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL552_21785	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL552_21790	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL552_21795	COG0762	integral membrane protein
AL552_21800	COG1872	DUF167
AL552_21810	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL552_21815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL552_21820	COG2066	Belongs to the glutaminase family
AL552_21830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL552_21840	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL552_21915	COG1012	belongs to the aldehyde dehydrogenase family
AL552_21955	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL552_21965	COG3394	polysaccharide catabolic process
AL552_21970	COG1486	melibiose metabolic process
AL552_21975	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL552_21980	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL552_21990	COG0726	polysaccharide deacetylase
AL552_22000	COG1028	Short-chain dehydrogenase reductase Sdr
AL552_22005	COG4325	translation initiation factor activity
AL552_22015	COG0795	lipopolysaccharide-transporting ATPase activity
AL552_22020	COG0795	lipopolysaccharide-transporting ATPase activity
AL552_22030	COG2927	DNA polymerase III (CHI subunit)
AL552_22035	COG0525	valine-tRNA ligase activity
AL552_22045	COG0456	acetyltransferase
AL552_22075	COG0540	Belongs to the ATCase OTCase family
AL552_22080	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AL552_22085	COG0251	oxidation-reduction process
AL552_22090	COG0204	Acyl-transferase
AL552_22095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL552_22100	COG5007	Belongs to the BolA IbaG family
AL552_22110	COG2854	intermembrane phospholipid transfer
AL552_22115	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL552_22120	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL552_22125	COG1127	ABC transporter
AL552_22145	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL552_22150	COG1137	ATPase activity
AL552_22160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL552_22165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL552_22170	COG1660	Displays ATPase and GTPase activities
AL552_22175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL552_22180	COG2239	Acts as a magnesium transporter
AL552_22185	COG0312	modulator of DNA gyrase
AL552_22190	COG3028	Belongs to the UPF0307 family
AL552_22195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL552_22200	COG0564	pseudouridine synthase activity
AL552_22210	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL552_22215	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL552_22220	COG0312	modulator of DNA gyrase
AL552_22225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL552_22230	COG3164	Protein of unknown function
AL552_22235	COG1530	ribonuclease E activity
AL552_22240	COG0424	maF-like protein
AL552_22245	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL552_22250	COG1792	Involved in formation and maintenance of cell shape
AL552_22255	COG1077	Cell shape determining protein MreB Mrl
AL552_22300	COG1459	type II secretion system
AL552_22305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL552_22315	COG3409	Peptidoglycan-binding domain 1 protein
AL552_22315	COG3267	Type II secretory pathway component ExeA
AL552_22320	COG1450	Type ii and iii secretion system protein
AL552_22340	COG2199	diguanylate cyclase activity
AL552_22340	COG2200	EAL domain
AL552_22345	COG0629	single-stranded DNA binding
AL552_22360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL552_22370	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL552_22385	COG0527	aspartate kinase activity
AL552_22460	COG0175	sulfate reduction
AL552_22465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL552_22470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL552_22490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL552_22495	COG0735	belongs to the Fur family
AL552_22505	COG0166	Belongs to the GPI family
AL552_22510	COG0432	Pfam Uncharacterised protein family UPF0047
AL552_22520	COG0305	Participates in initiation and elongation during chromosome replication
AL552_22540	COG2965	DNA replication, synthesis of RNA primer
AL552_22545	COG0360	Binds together with S18 to 16S ribosomal RNA
AL552_22550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL552_22555	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AL552_22565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL552_22570	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL552_22600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL552_22610	COG0678	peroxiredoxin activity
AL552_22610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL552_22630	COG0165	Argininosuccinate lyase
AL552_22630	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL552_22635	COG0137	argininosuccinate synthase activity
AL552_22645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL552_22655	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL552_22665	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL552_22670	COG0527	aspartate kinase activity
AL552_22670	COG0460	homoserine dehydrogenase
AL552_22675	COG0626	cystathionine gamma-synthase activity
AL552_22685	COG0281	malic enzyme
AL552_22695	COG2906	2 iron, 2 sulfur cluster binding
AL552_22700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL552_22705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL552_22720	COG2168	tRNA wobble position uridine thiolation
AL552_22725	COG2923	Belongs to the DsrF TusC family
AL552_22730	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL552_22735	COG2964	Protein conserved in bacteria
AL552_22740	COG0545	Peptidyl-prolyl cis-trans isomerase
AL552_22755	COG1446	asparaginase
AL552_22760	COG1047	Peptidyl-prolyl cis-trans
AL552_22775	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL552_22785	COG0488	(ABC) transporter
AL552_22795	COG0429	hydrolase of the alpha beta-hydrolase fold
AL552_22800	COG3089	Belongs to the UPF0270 family
AL552_22805	COG3954	Phosphoribulokinase
AL552_22810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL552_22830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL552_22850	COG0180	Tryptophanyl-tRNA synthetase
AL552_22855	COG0546	phosphoglycolate phosphatase activity
AL552_22860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL552_22865	COG0557	exoribonuclease II activity
AL552_22870	COG1959	2 iron, 2 sulfur cluster binding
AL552_22875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL552_22875	COG1017	nitric oxide dioxygenase activity
AL552_22880	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AL552_22890	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL552_22895	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL552_22900	COG0330	HflC and HflK could
AL552_22905	COG0330	HflC and HflK could
AL552_22910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL552_22920	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL552_22925	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL552_22935	COG0802	atpase or kinase
AL552_22945	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL552_23010	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL552_23015	COG1162	GTPase activity
AL552_23020	COG0688	phosphatidylethanolamine metabolic process
AL552_23025	COG0471	metal ion transport
AL552_23035	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL552_23040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL552_23045	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL552_23050	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL552_23055	COG1045	serine acetyltransferase
AL552_23060	COG4942	peptidase
AL552_23080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AL552_23085	COG1053	succinate dehydrogenase
AL552_23090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL552_23095	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL552_23115	COG1509	lysine 2,3-aminomutase activity
AL552_23120	COG1285	pathogenesis
AL552_23130	COG0459	protein refolding
AL552_23135	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL552_23140	COG0534	Mate efflux family protein
AL552_23145	COG0205	6-phosphofructokinase activity
AL552_23150	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AL552_23155	COG3678	ATP-independent chaperone mediated protein folding
AL552_23160	COG0745	RESPONSE REGULATOR receiver
AL552_23165	COG2205	protein histidine kinase activity
AL552_23175	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL552_23180	COG3030	protein affecting phage T7 exclusion by the F plasmid
AL552_23185	COG1027	Aspartate ammonia-lyase
AL552_23190	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL552_23195	COG4232	protein-disulfide reductase activity
AL552_23205	COG3263	regulation of cellular component size
AL552_23215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL552_23240	COG2814	Major facilitator Superfamily
AL552_23255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL552_23260	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL552_23265	COG0511	ligase activity, forming carbon-carbon bonds
AL552_23270	COG0439	Biotin carboxylase
AL552_23280	COG2264	protein methyltransferase activity
AL552_23285	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL552_23290	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AL552_23300	COG0488	(ABC) transporter
AL552_23360	COG1982	Orn Lys Arg decarboxylase major
AL552_23365	COG0531	amino acid
AL552_23375	COG3710	Transcriptional regulator
AL552_23380	COG0789	Transcriptional regulator
AL552_23390	COG0138	bifunctional purine biosynthesis protein purh
AL552_23400	COG0151	Belongs to the GarS family
AL552_23415	COG1253	flavin adenine dinucleotide binding
AL552_23420	COG3068	Protein conserved in bacteria
AL552_23430	COG1573	uracil-dna glycosylase
AL552_23435	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL552_23440	COG2816	NAD+ diphosphatase activity
AL552_23445	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL552_23450	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL552_23455	COG0085	RNA polymerase activity
AL552_23460	COG0222	ribosome binding
AL552_23465	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL552_23480	COG0250	Participates in transcription elongation, termination and antitermination
AL552_23485	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL552_23495	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL552_23525	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AL552_23525	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AL552_23530	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL552_23540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL552_23620	COG4206	TonB-dependent receptor
AL552_23665	COG2003	Belongs to the UPF0758 family
AL552_23670	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL552_23680	COG0732	type I restriction modification DNA specificity domain
AL552_23685	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL552_23710	COG3302	dmso reductase anchor subunit
AL552_23715	COG0437	4 iron, 4 sulfur cluster binding
AL552_23720	COG0243	molybdopterin cofactor binding
AL552_23730	COG2221	Nitrite and sulphite reductase 4Fe-4S
AL552_23730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL552_23735	COG5001	Diguanylate cyclase
AL552_23755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL552_23760	COG0534	Mate efflux family protein
AL552_23765	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AL552_23775	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL552_23785	COG2937	Belongs to the GPAT DAPAT family
AL552_23790	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AL552_23795	COG3161	chorismate lyase activity
AL552_23800	COG1580	Controls the rotational direction of flagella during chemotaxis
AL552_23805	COG0705	Rhomboid family
AL552_23810	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL552_23820	COG2177	Part of the ABC transporter FtsEX involved in
AL552_23825	COG2884	Cell division ATP-binding protein ftsE
AL552_23830	COG0552	protein localization to endoplasmic reticulum
AL552_23835	COG0742	ribosomal rna small subunit methyltransferase
AL552_23845	COG2095	MarC family integral membrane protein
AL552_23895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL552_23900	COG0640	Transcriptional regulator
AL552_23905	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL552_23910	COG1280	lysine exporter protein (LysE YggA)
AL552_23915	COG2267	carboxylic ester hydrolase activity
AL552_23920	COG0561	phosphatase activity
AL552_23940	COG2200	EAL domain
AL552_23940	COG3287	FIST C domain
AL552_23940	COG2199	diguanylate cyclase activity
AL552_23945	COG1011	Hydrolase
AL552_23950	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL552_23960	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL552_23965	COG0019	diaminopimelate decarboxylase activity
AL552_23975	COG1965	Belongs to the frataxin family
AL552_23980	COG3072	Adenylate cyclase
AL552_23985	COG0181	hydroxymethylbilane synthase activity
AL552_23990	COG1587	Uroporphyrinogen-III synthase
AL552_23995	COG2959	enzyme of heme biosynthesis
AL552_24000	COG3071	HemY protein
AL552_24045	COG0633	Ferredoxin
AL552_24050	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL552_24065	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL552_24070	COG3118	belongs to the thioredoxin family
AL552_24075	COG0513	Belongs to the DEAD box helicase family
AL552_24080	COG0248	Ppx GppA phosphatase
AL552_24085	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL552_24095	COG0514	ATP-dependent DNA helicase (RecQ)
AL552_24100	COG2962	Rard protein
AL552_24125	COG0210	DNA helicase
AL552_24135	COG3220	belongs to the UPF0276 family
AL552_24165	COG0006	proline dipeptidase activity
AL552_24165	COG0006	proline dipeptidase activity
AL552_24180	COG2104	thiamine diphosphate biosynthetic process
AL552_24185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL552_24200	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL552_24205	COG2132	Multicopper oxidase
AL552_24260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL552_24265	COG1739	Uncharacterized protein family UPF0029
AL552_24275	COG0183	Belongs to the thiolase family
AL552_24280	COG0604	alcohol dehydrogenase
AL552_24295	COG0425	Belongs to the sulfur carrier protein TusA family
AL552_24305	COG2119	membrane
AL552_24320	COG0366	Alpha amylase catalytic
AL552_24325	COG3977	Valine--pyruvate aminotransferase
AL552_24330	COG0071	Belongs to the small heat shock protein (HSP20) family
AL552_24345	COG0187	DNA topoisomerase II activity
AL552_24355	COG0592	DNA-directed DNA polymerase activity
AL552_24360	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL552_24380	COG1126	abc transporter atp-binding protein
AL552_24390	COG0594	ribonuclease P activity
AL552_24395	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL552_24400	COG0706	membrane insertase activity
AL552_24410	COG4974	Belongs to the 'phage' integrase family
AL552_24515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL552_24520	COG0445	tRNA wobble uridine modification
AL552_24525	COG0357	Ribosomal RNA small subunit methyltransferase G
AL552_24530	COG1192	Involved in chromosome partitioning
AL552_24535	COG1475	DNA binding
AL552_24540	COG3312	ion transport
AL552_24545	COG0356	it plays a direct role in the translocation of protons across the membrane
AL552_24555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL552_24565	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL552_24570	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL552_24575	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL552_24580	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL552_24590	COG0765	amino acid transport
AL552_24600	COG2814	Major facilitator Superfamily
AL552_24605	COG0583	DNA-binding transcription factor activity
AL552_24615	COG0129	dihydroxy-acid dehydratase activity
AL552_24620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL552_24625	COG3978	acetolactate synthase activity
AL552_24635	COG0606	chelatase, subunit chli
AL552_24645	COG0204	Acyl-transferase
AL552_24650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL552_24655	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL552_24665	COG3084	Protein conserved in bacteria
AL552_24675	COG4326	sporulation control protein
AL552_24680	COG1272	protein, Hemolysin III
AL552_24690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL552_24695	COG0569	domain protein
AL552_24700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL552_24700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL552_24705	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL552_24710	COG0242	peptide deformylase activity
AL552_24720	COG0758	DNA mediated transformation
AL552_24725	COG2922	Belongs to the Smg family
AL552_24730	COG0551	DNA topoisomerase type I activity
AL552_24735	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL552_24740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL552_24745	COG0009	L-threonylcarbamoyladenylate synthase
AL552_24750	COG0408	coproporphyrinogen oxidase activity
AL552_24755	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL552_24765	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL552_24805	COG0583	DNA-binding transcription factor activity
AL552_24810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL552_24815	COG2960	long-chain fatty acid transporting porin activity
AL552_24820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL552_24825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL552_24880	COG4172	Belongs to the ABC transporter superfamily
AL552_24885	COG4166	transmembrane transport
AL552_24895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL552_24940	COG1609	Transcriptional regulator
AL552_24945	COG0583	DNA-binding transcription factor activity
AL552_24960	COG0129	dihydroxy-acid dehydratase activity
AL552_24965	COG3265	gluconokinase activity
AL552_24970	COG2610	gluconate transmembrane transporter activity
AL552_24975	COG0800	Aldolase
AL552_24980	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL552_24985	COG0583	DNA-binding transcription factor activity
AL552_24990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL552_24995	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL552_25005	COG1522	sequence-specific DNA binding
AL552_25010	COG5001	Diguanylate cyclase
AL552_25010	COG5002	protein histidine kinase activity
AL552_25015	COG0742	ribosomal rna small subunit methyltransferase
AL552_25025	COG0697	spore germination
AL552_25030	COG0589	response to stress
AL552_25035	COG1528	Iron-storage protein
AL552_25045	COG2081	HI0933 family
AL552_25075	COG1597	lipid kinase activity
AL552_25105	COG0628	permease
AL552_25120	COG1322	Protein conserved in bacteria
AL552_25125	COG2226	methyltransferase
AL552_25130	COG3165	ubiquinone biosynthetic process from chorismate
AL552_25135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL552_25150	COG0805	protein transport
AL552_25160	COG0084	hydrolase, TatD family'
AL552_25175	COG0456	acetyltransferase
AL552_25185	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL552_25185	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL552_25195	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL552_25225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL552_25230	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL552_25240	COG2204	response regulator
AL552_25245	COG3852	Histidine kinase
AL552_25255	COG0174	glutamine synthetase