locus-tag	class	description
HOO69_00065	ENOG4105EEQ	Na H antiporter
HOO69_00070	ENOG4105C3R	Methionine synthase
HOO69_00075	ENOG4105CJW	magnesium transporter
HOO69_00080	ENOG41080Z8	PHOSPHOCARRIER protein
HOO69_00085	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HOO69_00090	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HOO69_00095	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HOO69_00100	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HOO69_00105	ENOG4108IUZ	ABC transporter
HOO69_00110	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HOO69_00120	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
HOO69_00125	ENOG4105C2X	Arabinose 5-phosphate isomerase
HOO69_00135	ENOG4105DHJ	ABC, transporter
HOO69_00140	ENOG4105CY3	ABC transporter, permease
HOO69_00145	ENOG4107PE3	Mammalian cell entry related domain protein
HOO69_00150	ENOG4105E3I	toluene tolerance
HOO69_00155	ENOG4105UE2	Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane
HOO69_00160	ENOG4105VFK	BolA family
HOO69_00165	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HOO69_00170	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HOO69_00210	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_00235	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
HOO69_00240	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HOO69_00245	ENOG4105CEN	a g-specific adenine glycosylase
HOO69_00255	ENOG4105CSV	Glutaminase
HOO69_00260	ENOG4105CSA	Coproporphyrinogen iii oxidase
HOO69_00275	ENOG4105VZ9	UPF0235 protein
HOO69_00280	ENOG4108VIA	integral membrane protein
HOO69_00285	ENOG4105II7	pyrroline-5-carboxylate reductase
HOO69_00290	ENOG4105DFA	alanine racemase domain protein
HOO69_00295	ENOG4105CZX	twitching motility protein
HOO69_00300	ENOG4105CZX	twitching motility protein
HOO69_00310	ENOG4105CE1	Ferrous iron transport protein b
HOO69_00335	ENOG4105CJ1	ABC, transporter
HOO69_00355	ENOG4105D7Z	glutathione synthase
HOO69_00360	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HOO69_00365	ENOG4105RWS	endonuclease I
HOO69_00370	ENOG4105GPY	SprT protein
HOO69_00380	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HOO69_00385	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HOO69_00405	ENOG4105D2N	Aldolase
HOO69_00410	ENOG4105D64	Mechanosensitive ion channel
HOO69_00425	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HOO69_00430	ENOG4105MPN	Membrane
HOO69_00435	ENOG4105BZU	Histidine kinase
HOO69_00450	ENOG410804X	Transcriptional regulator
HOO69_00455	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HOO69_00460	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HOO69_00465	ENOG4105E61	Mannitol repressor protein
HOO69_00470	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
HOO69_00475	ENOG4105CTS	PTS system mannitol-specific
HOO69_00480	ENOG4105CH5	extracellular solute-binding protein, family 7
HOO69_00490	ENOG4105EAH	synthase
HOO69_00495	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HOO69_00505	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HOO69_00510	ENOG4107XM3	UPF0442 protein
HOO69_00515	ENOG4107XM3	UPF0442 protein
HOO69_00520	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HOO69_00525	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HOO69_00530	ENOG4105NWN	ApaG protein
HOO69_00540	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HOO69_00545	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HOO69_00550	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HOO69_00555	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HOO69_00560	ENOG4108KU3	Integrase
HOO69_00590	ENOG4105VZ1	Replication Protein
HOO69_00640	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HOO69_00645	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HOO69_00650	ENOG4105KTH	gatB Yqey
HOO69_00655	ENOG4105VCC	30S ribosomal protein S21
HOO69_00660	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HOO69_00665	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HOO69_00670	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HOO69_00675	ENOG4107ZVW	dihydroneopterin aldolase
HOO69_00680	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HOO69_00685	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HOO69_00690	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HOO69_00695	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HOO69_00700	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HOO69_00705	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HOO69_00710	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HOO69_00715	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HOO69_00720	ENOG4108K5P	(LipO)protein
HOO69_00725	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HOO69_00730	ENOG4108JU6	CBS domain protein
HOO69_00735	ENOG4106KVJ	cytochrome C assembly protein
HOO69_00740	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HOO69_00745	ENOG4105K5M	30s ribosomal protein S16
HOO69_00750	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HOO69_00755	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HOO69_00760	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HOO69_00770	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
HOO69_00780	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
HOO69_00785	ENOG4105D7Q	type ii secretion system
HOO69_00790	ENOG4107QHF	type ii secretion system protein e
HOO69_00800	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HOO69_00810	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
HOO69_00820	ENOG4105T95	Thiol disulfide interChange protein
HOO69_00825	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HOO69_00830	ENOG41073TP	transcriptional regulator
HOO69_00835	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HOO69_00840	ENOG4107QSN	dihydrolipoamide acetyltransferase
HOO69_00845	ENOG4107QN2	dihydrolipoyl dehydrogenase
HOO69_00850	ENOG410630P	Transcriptional regulator
HOO69_00855	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HOO69_00860	ENOG41077A9	carbonic anhydrase
HOO69_00865	ENOG4105CHH	sulfate transporter
HOO69_00870	ENOG4105DA5	(ABC) transporter
HOO69_00875	ENOG4105E3A	(ABC) transporter
HOO69_00880	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HOO69_00885	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HOO69_00890	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HOO69_00895	ENOG4105DJ0	Poly(A) Polymerase
HOO69_00900	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HOO69_00910	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HOO69_00915	ENOG4105CQ7	ATP-dependent helicase
HOO69_00920	ENOG4105BZ4	penicillin-binding protein
HOO69_00925	ENOG4105D78	K07001 NTE family protein
HOO69_00930	ENOG4107QIJ	Aconitate hydratase 2
HOO69_00935	ENOG4105XTV	UPF0231 protein
HOO69_00940	ENOG4108YZA	Nitrogen regulatory protein pii
HOO69_00960	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HOO69_00975	ENOG4105E2D	ec 3.2.1.52
HOO69_00980	ENOG4105RD7	BadF BadG BcrA BcrD
HOO69_00990	ENOG4108JQ7	(ABC) transporter
HOO69_00995	ENOG4105C3U	ABC transporter
HOO69_01000	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HOO69_01010	ENOG4107QRA	Extracellular solute-binding protein, family 5
HOO69_01015	ENOG4105BZU	Histidine kinase
HOO69_01020	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HOO69_01025	ENOG4105IPI	Membrane
HOO69_01030	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HOO69_01035	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HOO69_01050	ENOG4105DR5	peptidase
HOO69_01055	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HOO69_01065	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
HOO69_01070	ENOG4107QE9	Inherit from COG: Membrane
HOO69_01075	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HOO69_01080	ENOG4105HBR	Rna-binding protein
HOO69_01085	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HOO69_01090	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HOO69_01095	ENOG4105EEI	dihydropteroate synthase
HOO69_01100	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HOO69_01110	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HOO69_01115	ENOG4105BZU	Histidine kinase
HOO69_01120	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HOO69_01125	ENOG4105C1J	atp-dependent rna helicase
HOO69_01135	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HOO69_01145	ENOG4105CRK	lysyL-tRNA synthetase
HOO69_01150	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HOO69_01160	ENOG4105CPC	Aldo Keto reductase
HOO69_01170	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
HOO69_01175	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HOO69_01180	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HOO69_01185	ENOG4105HF0	Membrane
HOO69_01190	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HOO69_01195	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HOO69_01205	ENOG41063Z6	transcriptional regulator, lysR family
HOO69_01210	ENOG41080HT	Transcriptional regulator, arsr family
HOO69_01215	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HOO69_01220	ENOG4105CJR	Integral membrane protein (MviN
HOO69_01225	ENOG4105DTN	riboflavin biosynthesis protein ribF
HOO69_01230	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HOO69_01240	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HOO69_01245	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HOO69_01250	ENOG4107RAN	Peptidase, M16
HOO69_01265	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HOO69_01280	ENOG4108NEV	two component transcriptional regulator, LytTR family
HOO69_01285	ENOG4108HRK	Histidine kinase
HOO69_01290	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HOO69_01300	ENOG4105DR5	peptidase
HOO69_01310	ENOG4105C5H	ABC transporter
HOO69_01315	ENOG4107SC1	transglycosylase
HOO69_01320	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
HOO69_01325	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HOO69_01335	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
HOO69_01345	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
HOO69_01350	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HOO69_01355	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HOO69_01360	ENOG4105C34	Pseudouridine synthase
HOO69_01365	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HOO69_01370	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HOO69_01410	ENOG4107RZC	phospholipase d
HOO69_01415	ENOG4105ECY	inositol monophosphatase
HOO69_01425	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HOO69_01430	ENOG4105C3J	Cysteine desulfurase
HOO69_01435	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HOO69_01440	ENOG4108Z4V	iron-sulfur cluster assembly
HOO69_01445	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
HOO69_01450	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HOO69_01455	ENOG4108ZIT	Ferredoxin, 2FE-2S
HOO69_01460	ENOG4105WVQ	Fe-S assembly protein IscX
HOO69_01465	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HOO69_01470	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HOO69_01480	ENOG4105ETT	transcriptional Regulator, LysR family
HOO69_01490	ENOG4105ETT	transcriptional Regulator, LysR family
HOO69_01495	ENOG4108IQE	Amp-dependent synthetase and ligase
HOO69_01570	ENOG41064T2	transcriptional regulator, lysR family
HOO69_01585	ENOG4105DRS	transport system, permease
HOO69_01590	ENOG4105XN3	extracellular solute-binding protein family 1
HOO69_01595	ENOG4105CNT	hydrolase family 2
HOO69_01605	ENOG4107WCA	isomerase
HOO69_01610	ENOG4105FTV	AraC Family Transcriptional Regulator
HOO69_01635	ENOG4105E5D	amino acid
HOO69_01640	ENOG4105FK9	beta-D-galactosidase beta subunit
HOO69_01645	ENOG4105CNT	hydrolase family 2
HOO69_01650	ENOG4105CQ4	Transcriptional regulator
HOO69_01655	ENOG4105CMR	udp-glucose 4-epimerase
HOO69_01660	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
HOO69_01665	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HOO69_01670	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HOO69_01680	ENOG4105D3R	alkyl hydroperoxide reductase
HOO69_01685	ENOG4108JU3	Alkyl hydroperoxide reductase
HOO69_01690	ENOG4105EJC	lysr family transcriptional regulator
HOO69_01695	ENOG4107RGM	aldo keto reductase
HOO69_01705	ENOG4108Y51	tRNA-binding protein
HOO69_01720	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HOO69_01725	ENOG4105E98	transcriptional regulator DeoR family
HOO69_01730	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HOO69_01735	ENOG4105CXY	transporter
HOO69_01740	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
HOO69_01745	ENOG4105D3R	alkyl hydroperoxide reductase
HOO69_01750	ENOG4105C5Q	Transcriptional regulator
HOO69_01755	ENOG4107QP3	malate synthase g
HOO69_01760	ENOG4108I9X	Isocitrate lyase
HOO69_01765	ENOG4105W87	Cbs domain
HOO69_01770	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HOO69_01775	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HOO69_01780	ENOG4105VIE	preprotein translocase, subunit YajC
HOO69_01785	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HOO69_01790	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HOO69_01800	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HOO69_01815	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HOO69_01820	ENOG4105CFP	Peptidase U32
HOO69_01825	ENOG4105DH7	May be involved in recombination (By similarity)
HOO69_01830	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HOO69_01835	ENOG4105BZU	Histidine kinase
HOO69_01840	ENOG4105DJH	phosphate
HOO69_01845	ENOG4105C9X	ppx gppa phosphatase
HOO69_01850	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HOO69_01855	ENOG4105C8U	phosphate abc transporter
HOO69_01860	ENOG4105E2Z	phosphate ABC transporter (Permease
HOO69_01865	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HOO69_01895	ENOG4106N3A	copper homeostasis protein cutc
HOO69_01900	ENOG4105X2V	dna damage-inducible protein
HOO69_01905	ENOG4108IND	Tetr family transcriptional regulator
HOO69_01910	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HOO69_01920	ENOG4105JQN	Transcriptional regulator
HOO69_01930	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HOO69_01935	ENOG4108IJ9	(ABC) transporter
HOO69_01950	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
HOO69_01965	ENOG4105DSY	exodeoxyribonuclease V, gamma
HOO69_01970	ENOG4107QKA	exodeoxyribonuclease V beta
HOO69_01975	ENOG4107QYX	exodeoxyribonuclease v alpha
HOO69_01985	ENOG4107QZM	n-acetylglutamate synthase
HOO69_01995	ENOG4105CA3	membrane-bound lytic murein transglycosylase
HOO69_02000	ENOG4105CUZ	uba thif-type nad fad binding protein
HOO69_02005	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HOO69_02010	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HOO69_02020	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HOO69_02025	ENOG4105CUT	histidyl-tRNA synthetase
HOO69_02030	ENOG4105N21	Membrane
HOO69_02035	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HOO69_02040	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HOO69_02050	ENOG4105BZU	Histidine kinase
HOO69_02060	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HOO69_02065	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HOO69_02080	ENOG4106HK8	GPR1 FUN34 yaaH family protein
HOO69_02085	ENOG4105BZG	amino acid carrier protein
HOO69_02115	ENOG4108IQK	o-acetylhomoserine
HOO69_02125	ENOG4105CC0	LysR family Transcriptional regulator
HOO69_02135	ENOG4105CY0	Metallo-Beta-Lactamase
HOO69_02140	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
HOO69_02145	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HOO69_02160	ENOG4105D8X	mechanosensitive ion channel
HOO69_02180	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HOO69_02185	ENOG4105D5U	fad dependent oxidoreductase
HOO69_02195	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
HOO69_02200	ENOG4105C94	Transporter
HOO69_02220	ENOG4105EIP	mannose-6-phosphate isomerase
HOO69_02225	ENOG4105CXY	transporter
HOO69_02230	ENOG4105BZU	Histidine kinase
HOO69_02235	ENOG4108KX4	response regulator
HOO69_02240	ENOG4105CXY	transporter
HOO69_02255	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HOO69_02260	ENOG4108Z1B	Cyclase dehydrase
HOO69_02265	ENOG4105VDB	UPF0125 protein
HOO69_02270	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HOO69_02275	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HOO69_02280	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HOO69_02285	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HOO69_02290	ENOG4105CK2	sodium dicarboxylate symporter
HOO69_02305	ENOG4105CFG	Acts as a chaperone (By similarity)
HOO69_02310	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HOO69_02340	ENOG4105CFC	Transporter
HOO69_02350	ENOG4108Z6B	deaminase
HOO69_02355	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HOO69_02360	ENOG4108ETH	Formylglycinamide ribotide synthetase
HOO69_02375	ENOG4105W1I	UPF0253 protein
HOO69_02385	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HOO69_02390	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HOO69_02395	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HOO69_02400	ENOG4105FE9	pseudouridine synthase
HOO69_02405	ENOG4108DG9	Smr protein MutS2
HOO69_02430	ENOG4105E2D	ec 3.2.1.52
HOO69_02435	ENOG4105DUX	Transporter
HOO69_02440	ENOG4105CAQ	asparagine synthetase
HOO69_02445	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HOO69_02450	ENOG4105E2R	ROK family
HOO69_02455	ENOG4105CE4	GlcNAc 6-P deacetylase
HOO69_02460	ENOG4105CI1	PTS System
HOO69_02475	ENOG41090R7	Ferric uptake
HOO69_02485	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HOO69_02495	ENOG4105EV9	Alpha Beta Hydrolase
HOO69_02500	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
HOO69_02505	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
HOO69_02515	ENOG4107QNR	UPF0135 protein
HOO69_02520	ENOG4105BZN	citrate synthase
HOO69_02525	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HOO69_02530	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HOO69_02535	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
HOO69_02540	ENOG4105E33	succinate dehydrogenase
HOO69_02545	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HOO69_02550	ENOG4105C7S	Dehydrogenase
HOO69_02555	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HOO69_02560	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HOO69_02585	ENOG4105WP7	tRNA pseudouridine synthase C
HOO69_02590	ENOG4105DR9	pseudouridine synthase
HOO69_02595	ENOG4105QYK	bacteriophage lambda Bor protein homolog
HOO69_02600	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HOO69_02605	ENOG4105CTB	Polyprenyl synthetase
HOO69_02610	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HOO69_02615	ENOG4105E14	MotA TolQ exbB proton channel
HOO69_02620	ENOG4106VK6	Flagellar motor protein
HOO69_02625	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
HOO69_02630	ENOG4105ETT	transcriptional Regulator, LysR family
HOO69_02640	ENOG4105M08	Membrane
HOO69_02645	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HOO69_02655	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
HOO69_02660	ENOG4105EWT	decarboxylase family
HOO69_02675	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HOO69_02680	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
HOO69_02700	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HOO69_02705	ENOG4105KUZ	arsenate reductase
HOO69_02715	ENOG4108ZVF	(LipO)protein
HOO69_02725	ENOG4108W0S	formate-dependent nitrite reductase complex
HOO69_02730	ENOG4105EMU	Dehydrogenase
HOO69_02745	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HOO69_02750	ENOG4105DVI	reductase, NrfD
HOO69_02755	ENOG4105DA4	cytochrome c-type biogenesis protein
HOO69_02760	ENOG4107QX9	Thiol disulfide interChange protein
HOO69_02765	ENOG4108DMF	Cytochrome C biogenesis protein
HOO69_02775	ENOG4105QZU	Inner membrane protein YfeZ
HOO69_02780	ENOG4105EZR	dyp-type peroxidase family protein
HOO69_02785	ENOG4105I03	Flagellin
HOO69_02790	ENOG4105I03	Flagellin
HOO69_02795	ENOG4105I03	Flagellin
HOO69_02800	ENOG41063QE	flagellar protein FlaG
HOO69_02805	ENOG4107BRV	flagellar capping protein
HOO69_02815	ENOG4105MQ3	flagellar protein FliS
HOO69_02825	ENOG4105BZU	Histidine kinase
HOO69_02835	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
HOO69_02840	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HOO69_02845	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HOO69_02855	ENOG4108JIR	Flagellum-specific ATP synthase
HOO69_02870	ENOG4105X6C	Flagellar basal body-associated protein FliL
HOO69_02875	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HOO69_02880	ENOG4105DD5	Flagellar motor switch protein
HOO69_02885	ENOG4105VTB	flagellar biosynthesis protein fliO
HOO69_02890	ENOG4105CN7	Flagellar biosynthetic protein FliP
HOO69_02895	ENOG4105VS8	Flagellar biosynthetic protein fliq
HOO69_02900	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HOO69_02905	ENOG4105D00	flagellar biosynthetic protein flhB
HOO69_02910	ENOG4108DG9	Smr protein MutS2
HOO69_02915	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HOO69_02920	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HOO69_02925	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HOO69_02935	ENOG4105EN6	Membrane
HOO69_02940	ENOG4108BPE	-transporting atpase
HOO69_02955	ENOG4105MH2	YfcL protein
HOO69_02960	ENOG4105Q8W	reductase
HOO69_02965	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HOO69_02970	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HOO69_02975	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
HOO69_02980	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HOO69_02990	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
HOO69_03000	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HOO69_03005	ENOG4108S3P	Sporulation domain protein
HOO69_03010	ENOG4105E96	Colicin v production protein
HOO69_03015	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HOO69_03020	ENOG4105FAV	ABC, transporter
HOO69_03025	ENOG4105FDK	ABC transporter
HOO69_03030	ENOG4105NXV	High-affinity zinc uptake system protein
HOO69_03035	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
HOO69_03045	ENOG4105XFK	Ferrous iron transport protein A
HOO69_03050	ENOG4105CE1	Ferrous iron transport protein b
HOO69_03065	ENOG4105C75	arginyL-tRNA synthetase
HOO69_03075	ENOG4106ZCM	YecM protein
HOO69_03080	ENOG4107QXK	peptidase
HOO69_03085	ENOG4108BY2	phosphohistidine phosphatase
HOO69_03090	ENOG4105D7B	Flagellar biosynthesis protein flha
HOO69_03095	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HOO69_03105	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HOO69_03110	ENOG4108VYJ	response regulator receiver protein
HOO69_03115	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HOO69_03125	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HOO69_03130	ENOG4107QJE	Chromosome Partitioning Protein
HOO69_03140	ENOG4108V3W	Chemotaxis protein, CheW
HOO69_03150	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HOO69_03160	ENOG41060IM	Heme exporter protein
HOO69_03165	ENOG4105X3C	heme exporter protein
HOO69_03170	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HOO69_03175	ENOG4105DA4	cytochrome c-type biogenesis protein
HOO69_03180	ENOG4107QX9	Thiol disulfide interChange protein
HOO69_03185	ENOG4105KWW	Biogenesis protein
HOO69_03190	ENOG4108M1T	Cytochrome c-type biogenesis protein
HOO69_03195	ENOG410903C	(LipO)protein
HOO69_03200	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HOO69_03205	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HOO69_03220	ENOG4105CHU	acetyl-coa acetyltransferase
HOO69_03225	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HOO69_03230	ENOG41069NU	Nitroreductase
HOO69_03240	ENOG4105I93	response regulator
HOO69_03245	ENOG4105WD1	Membrane
HOO69_03250	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HOO69_03255	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HOO69_03260	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HOO69_03265	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HOO69_03270	ENOG4105KRS	Proteinase inhibitor
HOO69_03330	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HOO69_03335	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HOO69_03360	ENOG4108ZZ3	UPF0260 protein
HOO69_03385	ENOG4105EXC	Acyl-transferase
HOO69_03410	ENOG4105C94	Transporter
HOO69_03425	ENOG4105DHI	Methyltransferase
HOO69_03430	ENOG4107SDU	Methyl-accepting chemotaxis
HOO69_03435	ENOG4105DSB	aldose 1-epimerase
HOO69_03440	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HOO69_03445	ENOG4105E0X	reductase
HOO69_03455	ENOG4105VUT	cytoplasmic protein
HOO69_03460	ENOG4105K5B	UPF0225 protein
HOO69_03465	ENOG4105D58	Diguanylate phosphodiesterase
HOO69_03470	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HOO69_03475	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HOO69_03485	ENOG4107104	thymidine kinase
HOO69_03490	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HOO69_03510	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HOO69_03515	ENOG4105RKX	Protein of unknown function (DUF2498)
HOO69_03520	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HOO69_03530	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HOO69_03535	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HOO69_03555	ENOG4105HP8	regulator of competence-specific genes
HOO69_03560	ENOG4105ETE	Transcriptional regulator (LacI family
HOO69_03565	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
HOO69_03570	ENOG4106WF9	DNA-binding transcriptional regulator TorR
HOO69_03575	ENOG4107S90	membrAne
HOO69_03580	ENOG4106371	Methyltransferase
HOO69_03585	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
HOO69_03590	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
HOO69_03595	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
HOO69_03605	ENOG4107RGH	Aldehyde dehydrogenase
HOO69_03610	ENOG4105CEY	Amp-dependent synthetase and ligase
HOO69_03630	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HOO69_03635	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
HOO69_03640	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
HOO69_03645	ENOG41081XQ	Conserved Protein
HOO69_03650	ENOG4105C9M	aspartyl-trna synthetase
HOO69_03655	ENOG4108R99	pseudouridine synthase
HOO69_03665	ENOG4105VEQ	Cold shock protein
HOO69_03670	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HOO69_03675	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HOO69_03710	ENOG4105TMB	Formate nitrite transporter
HOO69_03735	ENOG4108J2R	molybdopterin oxidoreductase
HOO69_03770	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HOO69_03775	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_03790	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HOO69_03795	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HOO69_03810	ENOG4107YD3	Thioesterase
HOO69_03815	ENOG4105E02	MotA TolQ exbB proton channel
HOO69_03820	ENOG4105M8F	Biopolymer transport protein exbD tolR
HOO69_03830	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HOO69_03835	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HOO69_03840	ENOG4105UFD	tol-pal system protein YbgF
HOO69_03850	ENOG4105CDH	Citrulline--aspartate ligase
HOO69_03865	ENOG4108RNS	Exports L-alanine (By similarity)
HOO69_03890	ENOG4105DVF	Cytosine-specific methyltransferase
HOO69_03910	ENOG4105DM4	PTS System
HOO69_03920	ENOG4105EIP	mannose-6-phosphate isomerase
HOO69_03925	ENOG4105DM4	PTS System
HOO69_03930	ENOG4106R3P	AraC family transcriptional regulator
HOO69_03940	ENOG4108YRF	PTS System
HOO69_03945	ENOG4105DM4	PTS System
HOO69_03950	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HOO69_03965	ENOG41062D9	Histidine kinase
HOO69_03970	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HOO69_03980	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HOO69_03995	ENOG4107QPN	acyl-Coa dehydrogenase
HOO69_04000	ENOG4105RKW	reductase (By
HOO69_04005	ENOG4105CGK	Exodeoxyribonuclease III
HOO69_04010	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_04015	ENOG4105EZE	Cupin 4 family protein
HOO69_04020	ENOG4106428	Protein of unknown function (DUF2496)
HOO69_04025	ENOG4108URS	primosomal replication protein n''
HOO69_04030	ENOG4105EJ9	Membrane
HOO69_04035	ENOG4105DVT	helicase
HOO69_04050	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HOO69_04055	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HOO69_04060	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HOO69_04070	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HOO69_04080	ENOG4105D0M	Protease HtpX homolog
HOO69_04090	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
HOO69_04105	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HOO69_04115	ENOG4105RHG	
HOO69_04125	ENOG4107QTF	adenylosuccinate lyase
HOO69_04130	ENOG41075W9	High frequency lysogenization protein HflD homolog
HOO69_04145	ENOG4107RE1	Inosine-guanosine kinase
HOO69_04150	ENOG4108YX2	DNA-binding protein
HOO69_04155	ENOG4107S6Z	Na H antiporter
HOO69_04160	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HOO69_04165	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HOO69_04170	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HOO69_04175	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HOO69_04190	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HOO69_04205	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
HOO69_04220	ENOG4108JQ2	peptide transport system atp-binding protein
HOO69_04225	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
HOO69_04230	ENOG4108EU3	peptide transport system, permease
HOO69_04235	ENOG4108EKA	peptide transport system, permease
HOO69_04240	ENOG4108J59	Extracellular solute-binding protein, family 5
HOO69_04245	ENOG4105E51	psp operon transcriptional activator
HOO69_04250	ENOG41087YS	Phage shock protein A
HOO69_04255	ENOG4105YYT	phage shock protein B
HOO69_04280	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HOO69_04290	ENOG4107IFA	Lipase (EC 3.1.1.3)
HOO69_04295	ENOG4105C28	cystathionine
HOO69_04305	ENOG4105C8J	)-transporter
HOO69_04315	ENOG4108W1A	pseudouridine synthase
HOO69_04320	ENOG4105DR4	Methyltransferase
HOO69_04395	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
HOO69_04400	ENOG4108VGW	abc transporter atp-binding protein
HOO69_04405	ENOG4105CXZ	ABC transporter, permease
HOO69_04410	ENOG4105VNH	ABC transporter solute-binding protein
HOO69_04420	ENOG4105XZD	Fe-S protein
HOO69_04440	ENOG4105BZU	Histidine kinase
HOO69_04450	ENOG4105K9H	YciI-like protein
HOO69_04455	ENOG4105NAU	thioesterase Superfamily protein
HOO69_04460	ENOG4107835	probably involved in intracellular septation (By similarity)
HOO69_04470	ENOG4105BZU	Histidine kinase
HOO69_04475	ENOG4105BZU	Histidine kinase
HOO69_04485	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HOO69_04490	ENOG4108W5H	UPF0263 protein
HOO69_04495	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HOO69_04505	ENOG4105CQ2	DNA polymerase
HOO69_04510	ENOG4105WH1	Two component transcriptional regulator luxr family
HOO69_04515	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HOO69_04545	ENOG4105BZU	Histidine kinase
HOO69_04595	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HOO69_04600	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HOO69_04610	ENOG4107RJ1	sodium solute
HOO69_04620	ENOG4108QGT	oligogalacturonate-specific porin
HOO69_04625	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HOO69_04630	ENOG41080XP	Cbs domain
HOO69_04635	ENOG4107EJG	GntR family transcriptional regulator
HOO69_04640	ENOG4107EJG	GntR family transcriptional regulator
HOO69_04660	ENOG4105EY3	heparinase II III family protein
HOO69_04665	ENOG4105M5J	Cupin 2, conserved barrel domain protein
HOO69_04670	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
HOO69_04675	ENOG4108UHU	Aldolase
HOO69_04680	ENOG4105CK7	Sodium proline symporter
HOO69_04685	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HOO69_04700	ENOG4105CNN	ABC, transporter
HOO69_04705	ENOG4105CNN	ABC, transporter
HOO69_04710	ENOG4105C2J	ABC transporter
HOO69_04720	ENOG4105DKT	Transcriptional regulator
HOO69_04725	ENOG4108FN7	Aldo keto reductase
HOO69_04735	ENOG41061GT	Aldolase
HOO69_04740	ENOG4105CMG	Carbohydrate kinase
HOO69_04745	ENOG4105C0A	alcohol dehydrogenase
HOO69_04750	ENOG4105C26	Dehydrogenase
HOO69_04760	ENOG4108FUF	Transcriptional regulator, IclR family
HOO69_04765	ENOG4108FUF	Transcriptional regulator, IclR family
HOO69_04770	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
HOO69_04795	ENOG4105C5Y	PTS System
HOO69_04800	ENOG4105ETE	Transcriptional regulator (LacI family
HOO69_04805	ENOG4107R3K	hydrolase
HOO69_04810	ENOG4105D7K	pfkb domain protein
HOO69_04815	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
HOO69_04830	ENOG4105ETT	transcriptional Regulator, LysR family
HOO69_04835	ENOG4105DZW	Dipeptidase
HOO69_04840	ENOG4107RH7	Nicotinate phosphoribosyltransferase
HOO69_04850	ENOG4108RWI	nicotinamidase
HOO69_04865	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
HOO69_04870	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HOO69_04910	ENOG4105G7T	Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity)
HOO69_04915	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HOO69_04920	ENOG4105VUF	Transcriptional regulator
HOO69_04925	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HOO69_05010	ENOG4105CTD	carboxy-peptidase
HOO69_05015	ENOG410829K	Lysine exporter protein (Lyse ygga)
HOO69_05030	ENOG4105BZG	amino acid carrier protein
HOO69_05055	ENOG4105BZU	Histidine kinase
HOO69_05060	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HOO69_05065	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
HOO69_05070	ENOG4105F1J	Homogentisate 1,2-dioxygenase
HOO69_05080	ENOG4108RXX	maleylacetoacetate isomerase
HOO69_05100	ENOG4108ZG0	Ompa motb domain protein
HOO69_05115	ENOG4105CQB	FAD linked oxidase domain protein
HOO69_05130	ENOG4105CGP	Urocanate hydratase
HOO69_05135	ENOG4105C84	Histidine ammonia-lyase
HOO69_05140	ENOG41088SP	formiminoglutamate hydrolase
HOO69_05145	ENOG4105CI2	imidazolone-5-propionate hydrolase
HOO69_05150	ENOG4105CZE	histidine utilization repressor
HOO69_05155	ENOG4108N23	SpoOM-related protein
HOO69_05170	ENOG4105FQ6	thiopurine methyltransferase
HOO69_05175	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
HOO69_05180	ENOG4105CPI	Metal Dependent Phosphohydrolase
HOO69_05190	ENOG41067MG	lrgb family
HOO69_05195	ENOG4105VAW	lrga family
HOO69_05200	ENOG4105CJB	Exodeoxyribonuclease I
HOO69_05235	ENOG4108ETY	sodium dicarboxylate symporter
HOO69_05240	ENOG4105K4T	epimerase
HOO69_05245	ENOG4107RT4	flavin reductase domain protein
HOO69_05250	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HOO69_05255	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HOO69_05260	ENOG4108YZT	Adenosylcobinamide kinase
HOO69_05275	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
HOO69_05285	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
HOO69_05295	ENOG4105BZU	Histidine kinase
HOO69_05310	ENOG4107RSM	transcriptional regulator
HOO69_05315	ENOG4105DKW	ABC transporter
HOO69_05330	ENOG4108VKG	metal-dependent hydrolase
HOO69_05345	ENOG41090FY	type IV pilus biogenesis stability protein PilW
HOO69_05350	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HOO69_05355	ENOG4105CVG	Homoserine O-transsuccinylase
HOO69_05375	ENOG4107SDU	Methyl-accepting chemotaxis
HOO69_05385	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HOO69_05400	ENOG4107V40	secretion protein, HlyD family
HOO69_05430	ENOG4108ESY	Metal dependent phosphohydrolase
HOO69_05480	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HOO69_05535	ENOG4105CS6	Rhs element vgr protein
HOO69_05555	ENOG4105CR4	methylisocitrate lyase
HOO69_05560	ENOG4105BZN	citrate synthase
HOO69_05565	ENOG4108I0Z	Aconitate hydratase
HOO69_05570	ENOG4105C7F	AcnD-accessory protein PrpF
HOO69_05575	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HOO69_05590	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_05595	ENOG410667J	hydrolase
HOO69_05600	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HOO69_05605	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HOO69_05610	ENOG4105BZU	Histidine kinase
HOO69_05620	ENOG4105CDV	Ompa motb domain protein
HOO69_05640	ENOG4105DR4	Methyltransferase
HOO69_05645	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_05650	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HOO69_05655	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
HOO69_05660	ENOG4108MN8	Membrane
HOO69_05665	ENOG4105CDA	abc transporter atp-binding protein
HOO69_05670	ENOG4105DRP	amino acid AbC transporter
HOO69_05675	ENOG4105EZ7	amino acid ABC transporter
HOO69_05680	ENOG4107QXX	ABC transporter
HOO69_05690	ENOG4108VPT	UPF0234 protein
HOO69_05695	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HOO69_05720	ENOG4105DY2	Paraquat-inducible protein b
HOO69_05725	ENOG4105H2K	paraquat-inducible protein a
HOO69_05730	ENOG4105BZ1	(ABC) transporter
HOO69_05735	ENOG4108ZGC	gaf domain protein
HOO69_05740	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
HOO69_05745	ENOG4105CN1	protease
HOO69_05755	ENOG4105CD8	aminopeptidase N
HOO69_05765	ENOG4105C7I	Dehydrogenase
HOO69_05770	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HOO69_05775	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
HOO69_05780	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HOO69_05790	ENOG4105C5H	ABC transporter
HOO69_05805	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HOO69_05810	ENOG4105DAN	ATP-dependent protease
HOO69_05815	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
HOO69_05840	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HOO69_05845	ENOG4105DMQ	Methyltransferase
HOO69_05950	ENOG4105EYW	Ion transport protein
HOO69_05970	ENOG4108WC9	type VI secretion system effector, hcp1 family
HOO69_06000	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HOO69_06015	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HOO69_06025	ENOG4105C59	p-type ATPase
HOO69_06040	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HOO69_06045	ENOG4105Q9Y	Universal stress protein
HOO69_06050	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HOO69_06055	ENOG4107QI1	Mate efflux family protein
HOO69_06075	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HOO69_06085	ENOG4105D38	putrescine abc transporter
HOO69_06090	ENOG4107RUE	extracellular solute-binding protein family 1
HOO69_06095	ENOG4107RUE	extracellular solute-binding protein family 1
HOO69_06100	ENOG4108KHX	Diguanylate cyclase
HOO69_06125	ENOG4105QAX	Iron-sulfur
HOO69_06130	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HOO69_06160	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HOO69_06165	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_06170	ENOG4105QNF	Outer membrane lipoprotein
HOO69_06205	ENOG4105K4U	addiction module toxin, RelE StbE family
HOO69_06250	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HOO69_06270	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
HOO69_06295	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HOO69_06375	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HOO69_06430	ENOG4105C5H	ABC transporter
HOO69_06440	ENOG4105BZU	Histidine kinase
HOO69_06445	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HOO69_06455	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
HOO69_06460	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HOO69_06465	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HOO69_06470	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HOO69_06485	ENOG4106IUH	DTW domain containing protein
HOO69_06495	ENOG4108N3W	hemolysin secretion protein
HOO69_06500	ENOG4107TT5	NLP P60 protein
HOO69_06520	ENOG4108R6K	riboflavin synthase, subunit alpha
HOO69_06525	ENOG4107QI1	Mate efflux family protein
HOO69_06540	ENOG4105UYK	outer membrane protein a
HOO69_06560	ENOG4105BZU	Histidine kinase
HOO69_06565	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HOO69_06575	ENOG4105CPK	Glycosyl transferase (Group 1
HOO69_06595	ENOG4108UW5	maltose o-acetyltransferase
HOO69_06610	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HOO69_06635	ENOG4107ZY3	Histidine kinase
HOO69_06640	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HOO69_06680	ENOG4107EXC	regulatoR
HOO69_06685	ENOG4105CIC	tryptophan-specific transport protein
HOO69_06690	ENOG4105GTN	ParB Domain Protein Nuclease
HOO69_06695	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
HOO69_06735	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HOO69_06740	ENOG4105TMB	Formate nitrite transporter
HOO69_06745	ENOG4105WZK	nitrite reductase NADPH small subunit
HOO69_06750	ENOG4107QZF	nitrite reductase NADPH large subunit
HOO69_06755	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_06790	ENOG4108V9W	transcriptional regulatory protein
HOO69_06795	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
HOO69_06815	ENOG4109015	Biopolymer transport protein exbD tolR
HOO69_06840	ENOG410804D	Sensor Signal Transduction Histidine Kinase
HOO69_06845	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HOO69_06865	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HOO69_06875	ENOG4105C8V	SAICAR synthetase
HOO69_06895	ENOG41064T2	transcriptional regulator, lysR family
HOO69_06900	ENOG41076CZ	activating enzyme
HOO69_06905	ENOG4105G0K	glycine radical enzyme YjjI family
HOO69_06910	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_06920	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HOO69_06935	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HOO69_06940	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HOO69_06970	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
HOO69_07000	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HOO69_07015	ENOG4108I0Y	(ABC) transporter
HOO69_07020	ENOG4107QI1	Mate efflux family protein
HOO69_07025	ENOG4105CGD	Nad-dependent epimerase dehydratase
HOO69_07035	ENOG4105C2C	drug resistance transporter, Bcr CflA
HOO69_07040	ENOG4105I08	Pseudouridine synthase
HOO69_07045	ENOG4105CFI	type iii restriction protein res subunit
HOO69_07060	ENOG4105DHQ	Histidine kinase
HOO69_07075	ENOG4108M3R	transcriptional activator CadC
HOO69_07080	ENOG4105BZS	acriflavin resistance protein
HOO69_07085	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HOO69_07105	ENOG4108HPI	phosphatidate Cytidylyltransferase
HOO69_07130	ENOG4105CS6	Rhs element vgr protein
HOO69_07140	ENOG4105CKK	Glycosyl transferase, family 2
HOO69_07145	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HOO69_07150	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HOO69_07160	ENOG4105CCU	oxidase (Subunit III)
HOO69_07165	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HOO69_07170	ENOG4105E2S	oxidase) subunit II
HOO69_07185	ENOG4105CC0	LysR family Transcriptional regulator
HOO69_07205	ENOG4105CKI	cobalamin synthesis protein
HOO69_07220	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HOO69_07225	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
HOO69_07230	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
HOO69_07235	ENOG4108Z4V	iron-sulfur cluster assembly
HOO69_07240	ENOG4105DIW	FeS assembly protein SUFB
HOO69_07245	ENOG4105C3K	feS assembly ATPase SufC
HOO69_07250	ENOG4105JRK	feS assembly protein SufD
HOO69_07260	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HOO69_07270	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_07285	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
HOO69_07300	ENOG4105CA0	peroxidase
HOO69_07330	ENOG4105CS6	Rhs element vgr protein
HOO69_07340	ENOG4105FR1	rard protein
HOO69_07345	ENOG4105D5Q	Arginine ornithine antiporter
HOO69_07355	ENOG4108NRW	Phospholipase, patatin family
HOO69_07390	ENOG4105CH5	extracellular solute-binding protein, family 7
HOO69_07405	ENOG4105C5X	domain protein
HOO69_07410	ENOG4105EAQ	(twin-arginine translocation) pathway signal
HOO69_07415	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
HOO69_07440	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
HOO69_07450	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
HOO69_07465	ENOG4105D9U	N-acetyltransferase
HOO69_07470	ENOG4108JU8	Transcriptional regulator
HOO69_07475	ENOG4106K28	UPF0283 membrane protein
HOO69_07480	ENOG4105CM6	amino acid regulated cytosolic protein
HOO69_07495	ENOG4105CRQ	synthase (Component I)
HOO69_07510	ENOG4105P8F	nudix hydrolase
HOO69_07515	ENOG4105C44	Serine transporter
HOO69_07520	ENOG4105EJQ	L-serine dehydratase
HOO69_07530	ENOG4108K8S	endonuclease I
HOO69_07535	ENOG4105E0U	tyrosine-specific transport protein
HOO69_07545	ENOG4105CHH	sulfate transporter
HOO69_07555	ENOG4108N3W	hemolysin secretion protein
HOO69_07560	ENOG4105C5S	asparaginyl-tRNA synthetase
HOO69_07575	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HOO69_07585	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HOO69_07590	ENOG4105CGF	Aromatic amino acid aminotransferase
HOO69_07610	ENOG4105CQ7	ATP-dependent helicase
HOO69_07615	ENOG4107R1I	NAD-dependent malic enzyme
HOO69_07625	ENOG4107GZ4	SanA protein
HOO69_07630	ENOG4105BZU	Histidine kinase
HOO69_07650	ENOG4105C3M	thioredoxin reductase
HOO69_07655	ENOG4108JJ9	ABC, transporter
HOO69_07660	ENOG4108JJ8	(ABC) transporter
HOO69_07680	ENOG4105FE9	pseudouridine synthase
HOO69_07685	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HOO69_07690	ENOG4105DB7	PHP domain protein
HOO69_07700	ENOG4105CRQ	synthase (Component I)
HOO69_07705	ENOG4105DDQ	anthranilate synthase
HOO69_07710	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HOO69_07715	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HOO69_07720	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HOO69_07725	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HOO69_07730	ENOG4105CK2	sodium dicarboxylate symporter
HOO69_07750	ENOG4105CQ7	ATP-dependent helicase
HOO69_07780	ENOG4105BZU	Histidine kinase
HOO69_07790	ENOG4105CFG	Acts as a chaperone (By similarity)
HOO69_07795	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
HOO69_07960	ENOG41066XE	Type III export protein
HOO69_07990	ENOG4108KB1	transcriptional regulator, arac family
HOO69_08010	ENOG4105C72	UPF0176 protein
HOO69_08040	ENOG4108Z33	Thiol disulfide Interchange Protein
HOO69_08050	ENOG4105CK5	oxidoreductase
HOO69_08060	ENOG4105EJC	lysr family transcriptional regulator
HOO69_08080	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HOO69_08085	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HOO69_08090	ENOG4105DZ2	Transcriptional regulator
HOO69_08105	ENOG4105BZU	Histidine kinase
HOO69_08110	ENOG4105BZU	Histidine kinase
HOO69_08115	ENOG4105CCT	upf0313 protein
HOO69_08120	ENOG4105BZU	Histidine kinase
HOO69_08125	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HOO69_08130	ENOG4105BZU	Histidine kinase
HOO69_08135	ENOG4108V3W	Chemotaxis protein, CheW
HOO69_08140	ENOG4108V3W	Chemotaxis protein, CheW
HOO69_08145	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_08150	ENOG4105CBS	Chea signal transduction histidine kinase
HOO69_08170	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HOO69_08180	ENOG4105BZU	Histidine kinase
HOO69_08205	ENOG4105DWU	Membrane
HOO69_08215	ENOG4105DY8	decarboxylase
HOO69_08220	ENOG4106KNT	transcriptional regulator
HOO69_08225	ENOG4105C0A	alcohol dehydrogenase
HOO69_08230	ENOG41090BQ	Glutaredoxin
HOO69_08235	ENOG4105D0C	transport protein
HOO69_08240	ENOG4106YG3	ABC transporter
HOO69_08245	ENOG4105DSP	amino acid AbC transporter
HOO69_08250	ENOG4105E89	ABC transporter
HOO69_08255	ENOG4108JEH	abc transporter atp-binding protein
HOO69_08265	ENOG4105C6N	Formate acetyltransferase
HOO69_08275	ENOG4108NVR	Methyl-accepting chemotaxis
HOO69_08280	ENOG4105F1A	Pyruvate formate-lyase
HOO69_08290	ENOG4105XWI	UPF0304 protein
HOO69_08305	ENOG4105CYN	Serine protein kinase
HOO69_08310	ENOG4106AKX	UPF0229 protein
HOO69_08315	ENOG4105ED1	spovr family
HOO69_08320	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HOO69_08325	ENOG4105W49	UPF0434 protein
HOO69_08330	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HOO69_08335	ENOG4105BZ1	(ABC) transporter
HOO69_08340	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HOO69_08365	ENOG4105D60	lipoprotein releasing system transmembrane protein
HOO69_08370	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HOO69_08375	ENOG4105D60	lipoprotein releasing system transmembrane protein
HOO69_08385	ENOG4108JA2	transcriptioN-repair coupling factor
HOO69_08400	ENOG4105CEP	NADH dehydrogenase
HOO69_08405	ENOG4105D0Y	UPF0227 protein
HOO69_08430	ENOG4105K59	histidine triad (HIT) protein
HOO69_08435	ENOG4108NVR	Methyl-accepting chemotaxis
HOO69_08445	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
HOO69_08455	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HOO69_08460	ENOG4105CNU	cell division protein FtsK
HOO69_08470	ENOG4105DCF	alanine dehydrogenase
HOO69_08480	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HOO69_08485	ENOG4108DNC	Involved in acetate metabolism (By similarity)
HOO69_08490	ENOG4105BZU	Histidine kinase
HOO69_08495	ENOG4105CHF	Glutathione S-transferase
HOO69_08500	ENOG4108JQ7	(ABC) transporter
HOO69_08505	ENOG4105C3U	ABC transporter
HOO69_08510	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HOO69_08515	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HOO69_08520	ENOG4107QSI	ABC, transporter
HOO69_08530	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
HOO69_08545	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HOO69_08550	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HOO69_08555	ENOG4107RBB	ABC transporter, permease
HOO69_08565	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HOO69_08575	ENOG4108IJF	Heavy metal efflux pump, CzcA
HOO69_08615	ENOG4107QE9	Inherit from COG: Membrane
HOO69_08625	ENOG4105EFZ	amidohydrolase
HOO69_08650	ENOG4105BZU	Histidine kinase
HOO69_08665	ENOG4108MNP	Glycoprotein polysaccharide metabolism
HOO69_08670	ENOG4105C29	acyl-CoA thioesterase
HOO69_08680	ENOG4108XM1	transcriptional regulator AsnC family
HOO69_08685	ENOG4105C6T	cysteine synthase
HOO69_08705	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
HOO69_08710	ENOG4105HMI	Membrane
HOO69_08720	ENOG4105ETT	transcriptional Regulator, LysR family
HOO69_08725	ENOG4105CI1	PTS System
HOO69_08730	ENOG4105CEY	Amp-dependent synthetase and ligase
HOO69_08740	ENOG4108IPT	Naphthoate synthase
HOO69_08745	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
HOO69_08750	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HOO69_08755	ENOG4105E4F	Isochorismate synthase
HOO69_08760	ENOG4105CHM	Aminotransferase
HOO69_08765	ENOG4105DK2	UPF0207 protein
HOO69_08785	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HOO69_08790	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HOO69_08805	ENOG4105C1J	atp-dependent rna helicase
HOO69_08830	ENOG41061MD	high-affinity nickel-transporter
HOO69_08835	ENOG41090EM	Repressor of rcnA expression. Acts by binding specifically to the rcnA promoter in the absence of nickel and cobalt. In the presence of one of these metals, it has a weaker affinity for rcnA promoter
HOO69_08840	ENOG4105ERU	peptidase
HOO69_08845	ENOG4105UBK	short-chain dehydrogenase reductase
HOO69_08860	ENOG4105C0B	DNA polymerase III (alpha subunit)
HOO69_08870	ENOG4105DAG	ROK family
HOO69_08875	ENOG4105CA9	Pyruvate kinase
HOO69_08880	ENOG4108NRW	Phospholipase, patatin family
HOO69_08900	ENOG4105CI1	PTS System
HOO69_08905	ENOG4105F8V	Hydrolase, tatD family
HOO69_08910	ENOG4107QRG	dna polymerase iii
HOO69_08915	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HOO69_08920	ENOG4105HHA	aminodeoxychorismate lyase
HOO69_08930	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HOO69_08935	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HOO69_08940	ENOG4105CHR	reductase
HOO69_08945	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HOO69_08950	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HOO69_08955	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HOO69_08960	ENOG4105VGS	50s ribosomal protein l32
HOO69_08965	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HOO69_08975	ENOG4105EI2	Pseudouridine synthase
HOO69_08980	ENOG4105C03	ribonuclease
HOO69_08985	ENOG4105CHH	sulfate transporter
HOO69_08990	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HOO69_08995	ENOG4105CEY	Amp-dependent synthetase and ligase
HOO69_09000	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HOO69_09005	ENOG4105R8X	Outer membrane lipoprotein Slp
HOO69_09015	ENOG41072GX	Peptidase M22 Glycoprotease
HOO69_09020	ENOG4105DVT	helicase
HOO69_09030	ENOG4105CIY	formyltetrahydrofolate deformylase
HOO69_09035	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HOO69_09040	ENOG4105D07	Signal peptide peptidase, SppA
HOO69_09055	ENOG4105CSH	Transporter
HOO69_09060	ENOG4105HDK	L-asparaginase
HOO69_09070	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HOO69_09075	ENOG4105D1H	recombination factor protein RarA
HOO69_09080	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HOO69_09085	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HOO69_09095	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HOO69_09100	ENOG4105BZU	Histidine kinase
HOO69_09105	ENOG4108JJB	ABC transporter
HOO69_09110	ENOG4105C7J	ABC transporter, permease
HOO69_09125	ENOG4107R11	Transcriptional regulator
HOO69_09135	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
HOO69_09145	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HOO69_09150	ENOG4105CFV	Tetratricopeptide repeat protein
HOO69_09155	ENOG4105Q4A	inner membrane protein yciS
HOO69_09160	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HOO69_09165	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HOO69_09170	ENOG4105CAT	Cytidine monophosphate kinase
HOO69_09175	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HOO69_09180	ENOG4105EIN	peptidylprolyl cis-trans isomerase
HOO69_09185	ENOG4105K70	DNA-binding protein
HOO69_09190	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HOO69_09195	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HOO69_09200	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HOO69_09205	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HOO69_09210	ENOG4105CQZ	Histidine kinase
HOO69_09220	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HOO69_09225	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
HOO69_09230	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HOO69_09235	ENOG4108IJ9	(ABC) transporter
HOO69_09240	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
HOO69_09255	ENOG4105E0F	Histidine kinase
HOO69_09270	ENOG4105BZU	Histidine kinase
HOO69_09275	ENOG4108N3W	hemolysin secretion protein
HOO69_09295	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HOO69_09300	ENOG4105D9N	nucleoside
HOO69_09305	ENOG4105EQ2	LysR family Transcriptional regulator
HOO69_09310	ENOG4105CVE	Lytic murein transglycosylase
HOO69_09315	ENOG4105VNG	YcgL domain-containing protein
HOO69_09325	ENOG4107QMS	site-determining protein
HOO69_09335	ENOG4108NVR	Methyl-accepting chemotaxis
HOO69_09340	ENOG4105C0A	alcohol dehydrogenase
HOO69_09345	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HOO69_09350	ENOG4105EYW	Ion transport protein
HOO69_09360	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HOO69_09365	ENOG4105DFD	Na H antiporter
HOO69_09380	ENOG4106V8H	Nucleoid-associated protein
HOO69_09385	ENOG4105YDX	UPF0352 protein
HOO69_09390	ENOG4105E68	Sulfatase
HOO69_09405	ENOG4105M6F	mutator MutT protein
HOO69_09410	ENOG4105DGU	Histone deacetylase
HOO69_09415	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
HOO69_09420	ENOG41060NJ	transcriptional regulator
HOO69_09435	ENOG4105DRS	transport system, permease
HOO69_09445	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HOO69_09450	ENOG4105ETE	Transcriptional regulator (LacI family
HOO69_09455	ENOG4108RU0	short-chain dehydrogenase reductase
HOO69_09475	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HOO69_09480	ENOG4105M2J	Glutaredoxin
HOO69_09485	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HOO69_09510	ENOG4108N3W	hemolysin secretion protein
HOO69_09515	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HOO69_09530	ENOG4105DBI	uridine monophosphokinase
HOO69_09535	ENOG4105D1F	ATP-binding protein
HOO69_09540	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HOO69_09555	ENOG4107SXA	Phosphorylase
HOO69_09580	ENOG4105BZU	Histidine kinase
HOO69_09585	ENOG4108ZAF	Molybdopterin
HOO69_09590	ENOG4105M00	molybdopterin converting factor, subunit 1
HOO69_09595	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HOO69_09600	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HOO69_09610	ENOG4105CHW	UPF0052 protein
HOO69_09625	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HOO69_09640	ENOG4105CY5	solute-binding protein
HOO69_09660	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HOO69_09670	ENOG4105DGN	Electron transport complex
HOO69_09675	ENOG4108R3D	Electron transport complex
HOO69_09685	ENOG4105D6A	Electron transport complex
HOO69_09700	ENOG4105CSM	endonuclease III
HOO69_09705	ENOG4108UYE	Lactoylglutathione lyase
HOO69_09710	ENOG4106WH9	Protein of unknown function (DUF2753)
HOO69_09715	ENOG4105EIY	sodium-type flagellar protein motY
HOO69_09720	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HOO69_09725	ENOG4105D3Y	Na H antiporter
HOO69_09730	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HOO69_09740	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HOO69_09745	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HOO69_09750	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_09765	ENOG4105ERG	peptidase m48, ste24p
HOO69_09770	ENOG4105K89	arsenate reductase
HOO69_09775	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HOO69_09790	ENOG4105C2W	permease
HOO69_09795	ENOG4108Z66	YbaK ebsC protein
HOO69_09800	ENOG4105CGH	5'-nucleotidase
HOO69_09810	ENOG41063JG	Transcriptional regulator
HOO69_09820	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HOO69_09825	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HOO69_09830	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HOO69_09840	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HOO69_09845	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HOO69_09850	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HOO69_09855	ENOG4105C3G	gtp-binding protein
HOO69_09960	ENOG4105I03	Flagellin
HOO69_09965	ENOG4105I03	Flagellin
HOO69_09970	ENOG4105DTJ	flagellar hook-associated protein
HOO69_09980	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HOO69_09985	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HOO69_09990	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HOO69_09995	ENOG4105CGA	flagellar basal-body rod protein FlgG
HOO69_10000	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HOO69_10005	ENOG4105BZE	flagellar hook protein, FlgE
HOO69_10010	ENOG4105W00	Flagellar hook capping protein
HOO69_10015	ENOG4108ZC9	flagellar basal-body rod protein flgc
HOO69_10020	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HOO69_10025	ENOG4105BZU	Histidine kinase
HOO69_10030	ENOG4107R88	Chemotaxis protein (CheV)
HOO69_10075	ENOG4107RRE	RNA-directed DNA polymerase
HOO69_10110	ENOG4108KU3	Integrase
HOO69_10120	ENOG4105UYK	outer membrane protein a
HOO69_10125	ENOG4108ZG0	Ompa motb domain protein
HOO69_10130	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HOO69_10140	ENOG41081QG	Porin Gram-negative type
HOO69_10145	ENOG4105C59	p-type ATPase
HOO69_10170	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HOO69_10175	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HOO69_10185	ENOG4108DQ1	activator toxR
HOO69_10205	ENOG4108RE9	Phosphodiesterase
HOO69_10230	ENOG4105ECP	epimerase
HOO69_10235	ENOG4105E1F	short-chain dehydrogenase reductase
HOO69_10240	ENOG4107QR8	Thioredoxin
HOO69_10245	ENOG4107QX8	SPFH domain, Band 7 family protein
HOO69_10265	ENOG41081QG	Porin Gram-negative type
HOO69_10270	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HOO69_10275	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HOO69_10280	ENOG4105EXN	Sulfate transport protein CysZ
HOO69_10285	ENOG4105C6T	cysteine synthase
HOO69_10290	ENOG4105KZ7	phosphocarrier protein hpr
HOO69_10295	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HOO69_10300	ENOG4105C5Y	PTS System
HOO69_10305	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HOO69_10310	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HOO69_10315	ENOG4105C9A	Phoh family
HOO69_10325	ENOG4108JU5	Magnesium and cobalt efflux protein
HOO69_10330	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HOO69_10335	ENOG4107PAI	alpha helical protein
HOO69_10340	ENOG4105C8T	Leucyl-tRNA synthetase
HOO69_10345	ENOG4108U2H	Rare lipoprotein B
HOO69_10350	ENOG4105DJF	DNA polymerase III, delta' subunit
HOO69_10355	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HOO69_10360	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HOO69_10370	ENOG4105CNI	cell division protein FtsW
HOO69_10375	ENOG4105K6T	rare lipoprotein A
HOO69_10380	ENOG4105DZ1	carboxypeptidase
HOO69_10390	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HOO69_10395	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HOO69_10405	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HOO69_10415	ENOG4105BZS	acriflavin resistance protein
HOO69_10445	ENOG4105CG3	alpha amylase, catalytic region
HOO69_10450	ENOG4105C5Y	PTS System
HOO69_10455	ENOG4105D4X	repressor
HOO69_10465	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HOO69_10470	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HOO69_10475	ENOG4108UMI	ABC transporter, permease
HOO69_10480	ENOG4105D01	(LipO)protein
HOO69_10490	ENOG4105CFC	Transporter
HOO69_10500	ENOG4105NRA	50s ribosomal protein l31 type b
HOO69_10505	ENOG4108R96	Methyltransferase, YaeB family
HOO69_10510	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HOO69_10515	ENOG4105E7A	Glutamine amidotransferase
HOO69_10520	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HOO69_10525	ENOG4107QPN	acyl-Coa dehydrogenase
HOO69_10535	ENOG4107RZZ	dna polymerase iii epsilon subunit
HOO69_10545	ENOG4105D1A	Methyltransferase
HOO69_10555	ENOG4105E9H	Lytic Murein transglycosylase
HOO69_10565	ENOG4107NA1	Endonuclease Exonuclease phosphatase
HOO69_10570	ENOG4108YZA	Nitrogen regulatory protein pii
HOO69_10575	ENOG4105N7H	Cytochrome
HOO69_10580	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HOO69_10585	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HOO69_10590	ENOG4105C0B	DNA polymerase III (alpha subunit)
HOO69_10595	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HOO69_10605	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HOO69_10610	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HOO69_10615	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HOO69_10620	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
HOO69_10625	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HOO69_10630	ENOG4105DZP	Membrane-associated zinc metalloprotease
HOO69_10635	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HOO69_10640	ENOG4105KNE	Phosphatidate cytidylyltransferase
HOO69_10645	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HOO69_10650	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HOO69_10655	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HOO69_10660	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HOO69_10665	ENOG4105CE9	30S ribosomal protein S2
HOO69_10670	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HOO69_10675	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
HOO69_10680	ENOG4108T8E	UPF0325 protein
HOO69_10685	ENOG4108ZAI	phosphatidylglycerophosphatase a
HOO69_10690	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HOO69_10695	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HOO69_10700	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HOO69_10715	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HOO69_10720	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HOO69_10725	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HOO69_10730	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HOO69_10740	ENOG4108DJV	Fermentation respiration switch protein
HOO69_10745	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
HOO69_10750	ENOG4105C7N	Xanthine uracil vitamin C permease
HOO69_10755	ENOG4105CIN	aminoacyl-histidine dipeptidase
HOO69_10760	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HOO69_10765	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HOO69_10775	ENOG4105C8J	)-transporter
HOO69_10795	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HOO69_10800	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HOO69_10815	ENOG4105CJ2	(LipO)protein
HOO69_10820	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
HOO69_10825	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HOO69_10830	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HOO69_10835	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HOO69_10840	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HOO69_10845	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HOO69_10850	ENOG4105M85	Bola protein
HOO69_10855	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
HOO69_10865	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HOO69_10870	ENOG4105EYM	Major Facilitator superfamily
HOO69_10880	ENOG4105K6V	RNA polymerase
HOO69_10895	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HOO69_10900	ENOG4107S0N	DJ-1 family
HOO69_10910	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HOO69_10920	ENOG4105EAC	phosphoserine phosphatase
HOO69_10930	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HOO69_10935	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
HOO69_10940	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
HOO69_10945	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
HOO69_10955	ENOG4105D9N	nucleoside
HOO69_10960	ENOG4105EYA	deoxyribonuclease
HOO69_10970	ENOG4105D1Q	UPF0246 protein
HOO69_10975	ENOG4105BZG	amino acid carrier protein
HOO69_10990	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HOO69_11010	ENOG4105EJ9	Membrane
HOO69_11015	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HOO69_11020	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HOO69_11025	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HOO69_11030	ENOG4105M6F	mutator MutT protein
HOO69_11035	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HOO69_11045	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HOO69_11050	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HOO69_11055	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HOO69_11060	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HOO69_11065	ENOG4105DFU	Cell wall formation (By similarity)
HOO69_11070	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HOO69_11080	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HOO69_11090	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HOO69_11095	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HOO69_11100	ENOG4105CJN	penicillin-binding protein
HOO69_11105	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HOO69_11110	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HOO69_11120	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HOO69_11125	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HOO69_11130	ENOG41082RQ	UPF0102 protein
HOO69_11135	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HOO69_11140	ENOG4105W4M	Transport-associated protein
HOO69_11145	ENOG4105KB2	stringent starvation protein b
HOO69_11150	ENOG4107MKT	Stringent starvation protein a
HOO69_11155	ENOG4105EIX	cytochrome c1
HOO69_11160	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HOO69_11165	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HOO69_11170	ENOG4108UJD	30S ribosomal protein S9
HOO69_11175	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HOO69_11180	ENOG4105D6Z	AFG1 family ATPase
HOO69_11185	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
HOO69_11190	ENOG4105C0H	protease
HOO69_11195	ENOG4105C0H	protease
HOO69_11200	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HOO69_11205	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HOO69_11210	ENOG4105IPS	esterase
HOO69_11215	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HOO69_11220	ENOG4108SX3	cytoplasmic protein
HOO69_11225	ENOG41087AY	ADP-Ribose pyrophosphatase
HOO69_11230	ENOG4105DFG	type I secretion outer membrane protein
HOO69_11240	ENOG4105BZU	Histidine kinase
HOO69_11250	ENOG4105N5T	Radical SAM Protein
HOO69_11265	ENOG4105CBC	glutamate synthase
HOO69_11270	ENOG4105BZ8	glutamate synthase
HOO69_11280	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HOO69_11285	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HOO69_11290	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HOO69_11295	ENOG4105CHV	Transcription elongation factor NusA
HOO69_11300	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HOO69_11315	ENOG4105NTZ	Preprotein translocase subunit SecG
HOO69_11320	ENOG4108YYD	acetyltransferase
HOO69_11330	ENOG4105BZU	Histidine kinase
HOO69_11360	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HOO69_11365	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HOO69_11380	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HOO69_11385	ENOG4105EN6	Membrane
HOO69_11390	ENOG4105D98	threonine synthase
HOO69_11395	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HOO69_11420	ENOG41065U4	response regulator
HOO69_11425	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HOO69_11430	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HOO69_11435	ENOG4108NVR	Methyl-accepting chemotaxis
HOO69_11440	ENOG4105EYW	Ion transport protein
HOO69_11445	ENOG4105I7R	Adenylate cyclase
HOO69_11450	ENOG4107IX6	phosphate transport regulator
HOO69_11460	ENOG4106MWK	domain protein
HOO69_11475	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HOO69_11480	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HOO69_11485	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HOO69_11490	ENOG4105DXN	mazG family
HOO69_11495	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HOO69_11505	ENOG4105BZU	Histidine kinase
HOO69_11510	ENOG4105BZU	Histidine kinase
HOO69_11525	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HOO69_11535	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HOO69_11540	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HOO69_11545	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HOO69_11550	ENOG4105C3F	Signal peptidase i
HOO69_11555	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HOO69_11560	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
HOO69_11565	ENOG4105VQK	sigma E regulatory protein, MucB RseB
HOO69_11575	ENOG4105EMN	RNA polymerase sigma factor
HOO69_11580	ENOG4108IYU	L-aspartate oxidase
HOO69_11590	ENOG4105Y75	tpr repeat protein
HOO69_11595	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HOO69_11610	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HOO69_11615	ENOG4105D0A	hydroxylase
HOO69_11625	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HOO69_11635	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HOO69_11645	ENOG4108JQ1	Dehydrogenase
HOO69_11650	ENOG4108ZP8	Acetolactate synthase small subunit
HOO69_11655	ENOG4105C7K	acetolactate synthase
HOO69_11660	ENOG4108IQE	Amp-dependent synthetase and ligase
HOO69_11665	ENOG41064T2	transcriptional regulator, lysR family
HOO69_11690	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HOO69_11695	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HOO69_11750	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HOO69_11770	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
HOO69_11780	ENOG4105D9M	gamma-glutamylcysteine synthetase
HOO69_11790	ENOG4105W39	Membrane
HOO69_11800	ENOG4105D9Q	decarboxylase (Beta subunit)
HOO69_11805	ENOG4107QSA	Oxaloacetate decarboxylase
HOO69_11855	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HOO69_11860	ENOG4105CFH	Aspartokinase
HOO69_11865	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HOO69_11870	ENOG4105Y3E	Modulates RecA activity (By similarity)
HOO69_11875	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HOO69_11880	ENOG4107TH8	cina domain protein
HOO69_11885	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HOO69_11890	ENOG4108K5H	permease YjgP YjgQ family protein
HOO69_11895	ENOG4108M8S	permease YjgP YjgQ family protein
HOO69_11900	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HOO69_11905	ENOG4105MYG	DNA polymerase iii, chi subunit
HOO69_11910	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HOO69_11920	ENOG4108M3P	Membrane
HOO69_11930	ENOG4105C5I	Dehydrogenase
HOO69_11935	ENOG4105D3G	Pseudouridine synthase
HOO69_11940	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HOO69_11945	ENOG4108IAB	Phoh family
HOO69_11950	ENOG4105DBV	ornithine carbamoyltransferase
HOO69_11955	ENOG4105CXT	aspartate transcarbamylase
HOO69_11960	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
HOO69_11965	ENOG4105KME	endoribonuclease L-psp
HOO69_11985	ENOG4105H1G	trap transporter solute receptor taxi family
HOO69_11995	ENOG41081QV	Universal stress protein
HOO69_12015	ENOG4105CEU	Arginine dihydrolase
HOO69_12020	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HOO69_12030	ENOG4105QD6	exported protein
HOO69_12035	ENOG4105C03	ribonuclease
HOO69_12045	ENOG4105VQ7	Rod shape-determining protein MreD
HOO69_12050	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HOO69_12100	ENOG4105D7Q	type ii secretion system
HOO69_12105	ENOG4107QHF	type ii secretion system protein e
HOO69_12120	ENOG4105GVR	general secretion pathway protein D
HOO69_12140	ENOG41062P1	Diguanylate cyclase phosphodiesterase
HOO69_12145	ENOG4108UUM	single-stranded DNA-binding protein
HOO69_12150	ENOG4108Q9V	regulatoR
HOO69_12155	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HOO69_12160	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HOO69_12170	ENOG4105C5R	Aminotransferase
HOO69_12175	ENOG4105CFH	Aspartokinase
HOO69_12185	ENOG4105N42	UPF0307 protein
HOO69_12190	ENOG4107T0D	ABC, transporter
HOO69_12195	ENOG4106SMU	thiamine transporter membrane protein
HOO69_12200	ENOG4105DP9	ABC transporter
HOO69_12205	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HOO69_12210	ENOG4105DFU	Cell wall formation (By similarity)
HOO69_12215	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HOO69_12225	ENOG41066HZ	AIG2-like family
HOO69_12230	ENOG4105MA0	exported protein
HOO69_12235	ENOG4105CFU	surface antigen
HOO69_12240	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HOO69_12245	ENOG4106322	response regulator
HOO69_12260	ENOG4108UUE	Transcriptional regulator
HOO69_12275	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HOO69_12295	ENOG4107QP8	phosphohexose isomerase
HOO69_12300	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HOO69_12315	ENOG4105KME	endoribonuclease L-psp
HOO69_12325	ENOG4105WWK	YheO domain protein
HOO69_12335	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HOO69_12340	ENOG4105CDU	Replicative dna helicase
HOO69_12350	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HOO69_12355	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HOO69_12360	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
HOO69_12370	ENOG4105DIJ	Phosphoethanolamine transferase
HOO69_12375	ENOG41080IJ	Diacylglycerol kinase
HOO69_12380	ENOG4108UQY	Iron-storage protein
HOO69_12385	ENOG4105W53	bacterioferritin-associated ferredoxin
HOO69_12395	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HOO69_12400	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HOO69_12405	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HOO69_12415	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
HOO69_12420	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HOO69_12425	ENOG4105WWK	YheO domain protein
HOO69_12430	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HOO69_12440	ENOG41069P5	Protein slyX homolog
HOO69_12450	ENOG4105EPW	hflc protein
HOO69_12455	ENOG4107QJR	hflk protein
HOO69_12460	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HOO69_12465	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HOO69_12470	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HOO69_12475	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HOO69_12480	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HOO69_12485	ENOG4105K8N	protein family UPF0079, ATPase
HOO69_12490	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HOO69_12550	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HOO69_12555	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HOO69_12560	ENOG4105DJ4	phosphatidylserine decarboxylase
HOO69_12565	ENOG4107QWE	)-transporter
HOO69_12570	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_12580	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HOO69_12585	ENOG41063SB	peptidase
HOO69_12595	ENOG4108IG5	Transcriptional regulator
HOO69_12600	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HOO69_12605	ENOG4105E09	nadh pyrophosphatase
HOO69_12610	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
HOO69_12615	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HOO69_12620	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HOO69_12625	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HOO69_12630	ENOG4108VZM	50s ribosomal protein L10
HOO69_12635	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HOO69_12640	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HOO69_12645	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HOO69_12650	ENOG4105PM1	preprotein translocase subunit SecE
HOO69_12655	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HOO69_12680	ENOG4105CS9	pantothenic acid kinase
HOO69_12695	ENOG4105CP7	Triose-phosphate isomerase
HOO69_12705	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HOO69_12710	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HOO69_12715	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HOO69_12720	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HOO69_12730	ENOG4105KT7	mgtC SapB transporter
HOO69_12735	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HOO69_12740	ENOG4105CTQ	phosphohexokinase
HOO69_12745	ENOG41076HS	cation diffusion facilitator family transporter
HOO69_12750	ENOG4108SPG	Periplasmic Protein
HOO69_12755	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HOO69_12760	ENOG4105E0F	Histidine kinase
HOO69_12765	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HOO69_12770	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HOO69_12780	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HOO69_12785	ENOG4105DJV	ribulose-phosphate 3-epimerase
HOO69_12790	ENOG4105DFE	Dna adenine methylase
HOO69_12800	ENOG4105D49	3-dehydroquinate synthase
HOO69_12805	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HOO69_12810	ENOG4105E4G	Type IV pilus
HOO69_12835	ENOG4108JQC	penicillin-binding protein 1A
HOO69_12840	ENOG4105C5Q	Transcriptional regulator
HOO69_12845	ENOG4105EHV	domain protein
HOO69_12850	ENOG4105M4H	endoribonuclease L-psp
HOO69_12860	ENOG4105CH7	arginosuccinase
HOO69_12865	ENOG4105CDH	Citrulline--aspartate ligase
HOO69_12870	ENOG4105CAS	nag kinase
HOO69_12875	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HOO69_12880	ENOG4105CWC	Acetylornithine deacetylase
HOO69_12885	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HOO69_12890	ENOG4105U3E	Transcriptional regulator
HOO69_12895	ENOG4105D7W	serine acetyltransferase
HOO69_12900	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HOO69_12905	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HOO69_12910	ENOG4107YZP	Rhodanese domain protein
HOO69_12915	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HOO69_12930	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HOO69_12935	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
HOO69_12950	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HOO69_12955	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HOO69_12960	ENOG41063M6	Cell Division Protein
HOO69_12965	ENOG4105ETE	Transcriptional regulator (LacI family
HOO69_12970	ENOG4105C25	Primosomal protein n'
HOO69_12975	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HOO69_12980	ENOG4105C6K	Malic enzyme
HOO69_12985	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
HOO69_12990	ENOG4105C28	cystathionine
HOO69_12995	ENOG4105CFH	Aspartokinase
HOO69_13005	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
HOO69_13010	ENOG4105CBT	Fructose-1,6-bisphosphatase
HOO69_13070	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HOO69_13085	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
HOO69_13090	ENOG4108Y73	Membrane
HOO69_13115	ENOG4107R73	Mate efflux family protein
HOO69_13125	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HOO69_13130	ENOG41080IJ	Diacylglycerol kinase
HOO69_13135	ENOG4105E55	glycerol-3-phosphate acyltransferase
HOO69_13140	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HOO69_13145	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HOO69_13150	ENOG4105X6C	Flagellar basal body-associated protein FliL
HOO69_13155	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
HOO69_13160	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HOO69_13165	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HOO69_13170	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HOO69_13175	ENOG4105CAK	Cell division ATP-binding protein ftsE
HOO69_13180	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HOO69_13185	ENOG4106H78	methyltransferase
HOO69_13195	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
HOO69_13235	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HOO69_13240	ENOG41082YX	Transcriptional regulator, arsr family
HOO69_13245	ENOG4105D58	Diguanylate phosphodiesterase
HOO69_13250	ENOG410829K	Lysine exporter protein (Lyse ygga)
HOO69_13255	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
HOO69_13260	ENOG4105DQF	Hydrolase
HOO69_13275	ENOG4106IUH	DTW domain containing protein
HOO69_13280	ENOG4105BZU	Histidine kinase
HOO69_13285	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HOO69_13290	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HOO69_13300	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HOO69_13305	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HOO69_13315	ENOG4105XQ6	frataxin-like protein
HOO69_13320	ENOG4107T0K	Adenylate cyclase
HOO69_13325	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HOO69_13330	ENOG41076E6	Uroporphyrinogen-III Synthase
HOO69_13335	ENOG4105ECF	c-methyltransferase
HOO69_13340	ENOG410601J	HemY protein
HOO69_13380	ENOG4107QK7	reductase
HOO69_13390	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HOO69_13400	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HOO69_13410	ENOG4105C1J	atp-dependent rna helicase
HOO69_13415	ENOG4105C9X	ppx gppa phosphatase
HOO69_13420	ENOG4105EX9	Membrane
HOO69_13430	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HOO69_13435	ENOG4105FR1	rard protein
HOO69_13445	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HOO69_13450	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HOO69_13455	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HOO69_13460	ENOG4105C4R	Atp-dependent dna helicase
HOO69_13470	ENOG4105E18	UPF0276 protein
HOO69_13490	ENOG4105DGW	oligopeptidase A
HOO69_13495	ENOG4105D6S	protein involved in catabolism of external DNA
HOO69_13505	ENOG4105DC8	reductase
HOO69_13525	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HOO69_13530	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HOO69_13535	ENOG4105DEF	Extracellular solute-binding protein, family 5
HOO69_13570	ENOG4105MPD	Cytochrome
HOO69_13575	ENOG4105C4R	Atp-dependent dna helicase
HOO69_13580	ENOG4105Y7M	Transcriptional regulator, TetR family
HOO69_13585	ENOG410624X	efflux transporter, rnd family, mfp subunit
HOO69_13590	ENOG4105BZS	acriflavin resistance protein
HOO69_13595	ENOG4105W0Z	cytoplasmic protein
HOO69_13605	ENOG4105EMY	transcriptional regulator
HOO69_13610	ENOG4105D4P	Coproporphyrinogen iii oxidase
HOO69_13620	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
HOO69_13635	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HOO69_13640	ENOG4105C2M	dna polymerase I
HOO69_13650	ENOG4105D52	delta-aminolevulinic acid dehydratase
HOO69_13655	ENOG4105F8V	Hydrolase, tatD family
HOO69_13660	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HOO69_13665	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HOO69_13670	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HOO69_13675	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HOO69_13680	ENOG4105JC1	sterol-binding domain protein
HOO69_13690	ENOG4105CGY	Dna recombination protein
HOO69_13700	ENOG4108HU6	Metal dependent phosphohydrolase
HOO69_13715	ENOG4105CBX	hi0933 family
HOO69_13720	ENOG4108V6B	universal stress protein B
HOO69_13725	ENOG41090A1	ferritin
HOO69_13730	ENOG4108M6U	Universal stress protein A
HOO69_13735	ENOG4105EMK	carboxylate amino acid amine transporter
HOO69_13745	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
HOO69_13750	ENOG4105BZU	Histidine kinase
HOO69_13755	ENOG4108VVK	transcriptional Regulator, AsnC
HOO69_13765	ENOG4105C2C	drug resistance transporter, Bcr CflA
HOO69_13770	ENOG4105G2Y	Transcriptional regulator
HOO69_13775	ENOG4105DC7	peptidase M24
HOO69_13775	ENOG4105DC7	peptidase M24
HOO69_13780	ENOG4105D41	biosynthesis protein thiH
HOO69_13785	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HOO69_13790	ENOG4105WHD	thiamine biosynthesis protein ThiS
HOO69_13795	ENOG4105D06	uba thif-type nad fad binding protein
HOO69_13805	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HOO69_13810	ENOG4105WMR	Protein CrcB homolog
HOO69_13815	ENOG4107R16	Multicopper oxidase
HOO69_13865	ENOG4108RR8	protoporphyrinogen oxidase
HOO69_13870	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HOO69_13875	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HOO69_13880	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HOO69_13885	ENOG4105CHU	acetyl-coa acetyltransferase
HOO69_13890	ENOG4105F52	Transcriptional regulator
HOO69_13895	ENOG4105CZQ	inner membrane transport protein YdhC
HOO69_13900	ENOG4105F87	Dehydratase
HOO69_13905	ENOG4105EAD	ABC transporter
HOO69_13910	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HOO69_13915	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HOO69_13920	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HOO69_13925	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HOO69_13930	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HOO69_13940	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HOO69_13950	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HOO69_13955	ENOG410684E	atp synthase
HOO69_13960	ENOG4105FA0	parb-like partition protein
HOO69_13965	ENOG4107QJE	Chromosome Partitioning Protein
HOO69_13970	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HOO69_13975	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HOO69_13980	ENOG4105QTB	Flavodoxin
HOO69_13985	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HOO69_13990	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HOO69_14000	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HOO69_14005	ENOG4105VG0	50S ribosomal protein l34
HOO69_14015	ENOG4105E5Q	amino acid AbC transporter
HOO69_14020	ENOG4105EAB	amino acid AbC transporter
HOO69_14025	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HOO69_14030	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HOO69_14035	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HOO69_14040	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HOO69_14045	ENOG4108ZNX	Heat shock protein
HOO69_14055	ENOG4105JKW	Valine--pyruvate aminotransferase
HOO69_14060	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HOO69_14065	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
HOO69_14080	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HOO69_14095	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
HOO69_14100	ENOG4105C7B	Threonine dehydratase
HOO69_14105	ENOG4105C01	Dihydroxy-acid dehydratase
HOO69_14110	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HOO69_14115	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
HOO69_14135	ENOG4105C79	DNA protecting protein DprA
HOO69_14180	ENOG4106HNH	Acyl-transferase
HOO69_14185	ENOG4108Z33	Thiol disulfide Interchange Protein
HOO69_14190	ENOG4105E27	serine threonine protein kinase
HOO69_14200	ENOG4105PC1	Conserved Protein
HOO69_14210	ENOG4108N23	SpoOM-related protein
HOO69_14215	ENOG4108UT2	hemolysin iii
HOO69_14220	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HOO69_14225	ENOG4105C1A	potassium transporter peripheral membrane
HOO69_14230	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HOO69_14235	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HOO69_14245	ENOG4108WZM	domain protein
HOO69_14250	ENOG4105C79	DNA protecting protein DprA
HOO69_14255	ENOG4108RPN	Protein smg homolog
HOO69_14260	ENOG4108WI1	Dna topoisomerase
HOO69_14265	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HOO69_14275	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HOO69_14280	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HOO69_14285	ENOG4105E2X	shikimate dehydrogenase
HOO69_14290	ENOG4105SG3	Protein of unknown function (DUF1488)
HOO69_14295	ENOG4108Z0R	Transferase
HOO69_14340	ENOG4105BZU	Histidine kinase
HOO69_14345	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HOO69_14350	ENOG4105CUX	Signal transduction histidine kinase
HOO69_14360	ENOG4105C5F	glutamine synthetase
HOO69_14365	ENOG4105CI3	gtp-binding protein typa
HOO69_14385	ENOG4107S2Z	UPF0761 membrane protein
HOO69_14395	ENOG4105SUU	thioesterase domain
HOO69_14405	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HOO69_14410	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HOO69_14415	ENOG4105VEJ	Heat shock protein
HOO69_14420	ENOG4108XKW	General secretion pathway protein C
HOO69_14430	ENOG4107QHF	type ii secretion system protein e
HOO69_14435	ENOG4105D7Q	type ii secretion system
HOO69_14440	ENOG4108VAU	general secretion pathway protein G
HOO69_14445	ENOG4105VWV	general secretion pathway protein h
HOO69_14450	ENOG4105X5Z	General secretion pathway protein I
HOO69_14455	ENOG4108WWZ	General secretion pathway protein J
HOO69_14460	ENOG4108RTD	type II secretion system protein K
HOO69_14465	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
HOO69_14470	ENOG4105U1E	general secretion pathway protein M
HOO69_14475	ENOG4105PIC	general secretion pathway protein N
HOO69_14480	ENOG4105E0F	Histidine kinase
HOO69_14500	ENOG4105BZM	domain protein
HOO69_14510	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HOO69_14515	ENOG4105MJ2	Competence protein
HOO69_14520	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
HOO69_14525	ENOG4107RK2	ADP-ribose diphosphatase NudE
HOO69_14530	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HOO69_14535	ENOG4105CB5	ATP-dependent DNA helicase recG
HOO69_14540	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HOO69_14545	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HOO69_14560	ENOG4105C7N	Xanthine uracil vitamin C permease
HOO69_14575	ENOG4105DSJ	YicC domain protein
HOO69_14585	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HOO69_14590	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
HOO69_14595	ENOG4105D1S	lipid A biosynthesis
HOO69_14600	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HOO69_14605	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HOO69_14610	ENOG4105W5Q	DNA repair protein (RadC
HOO69_14615	ENOG4105KDC	50s ribosomal protein l28
HOO69_14630	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HOO69_14635	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HOO69_14640	ENOG4105M5K	heptosyltransferase
HOO69_14645	ENOG4106WTF	Glycosyl transferase, family 2
HOO69_14650	ENOG4105DKP	glycosyl transferase, family 9
HOO69_14655	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
HOO69_14670	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HOO69_14680	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HOO69_14685	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HOO69_14690	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HOO69_14695	ENOG4108ST3	glycosyltransferase
HOO69_14700	ENOG4105XA0	heptosyltransferase ii
HOO69_14715	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
HOO69_14720	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HOO69_14725	ENOG4107QQG	Dehydrogenase
HOO69_14730	ENOG4105J5G	Transferase hexapeptide repeat containing protein
HOO69_14735	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HOO69_14745	ENOG4105C5E	polysaccharide biosynthesis protein
HOO69_14750	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HOO69_14755	ENOG4105F0R	Cytidylyltransferase
HOO69_14775	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HOO69_14815	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HOO69_14820	ENOG4108REZ	Imidazole glycerol phosphate synthase
HOO69_14835	ENOG4105CPK	Glycosyl transferase (Group 1
HOO69_14845	ENOG4105D3Q	Sugar transferase
HOO69_14855	ENOG4105JIM	Phosphatidylserine synthase
HOO69_14860	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HOO69_14865	ENOG4105D4A	Cell wall formation (By similarity)
HOO69_14890	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HOO69_14895	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HOO69_14900	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HOO69_14905	ENOG4108RG0	uracil-dna glycosylase
HOO69_14915	ENOG4105R2J	Conserved Protein
HOO69_14935	ENOG4105C12	Phosphoribosylglycinamide synthetase
HOO69_14940	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HOO69_14945	ENOG4105W1Y	Transcriptional regulator
HOO69_14950	ENOG4105BZU	Histidine kinase
HOO69_14955	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HOO69_14960	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HOO69_14965	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HOO69_14970	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HOO69_14975	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HOO69_14980	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HOO69_14985	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HOO69_15000	ENOG4105D8G	Major Facilitator superfamily
HOO69_15005	ENOG4105BZU	Histidine kinase
HOO69_15015	ENOG4107QN1	sodium solute
HOO69_15025	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HOO69_15035	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HOO69_15040	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
HOO69_15045	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
HOO69_15050	ENOG4105CXT	aspartate transcarbamylase
HOO69_15055	ENOG4105DBV	ornithine carbamoyltransferase
HOO69_15060	ENOG4105C5B	carbamate kinase
HOO69_15065	ENOG4105CEU	Arginine dihydrolase
HOO69_15070	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
HOO69_15075	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
HOO69_15080	ENOG4108IJ0	Aspartate ammonia-lyase
HOO69_15095	ENOG4105DDQ	anthranilate synthase
HOO69_15110	ENOG4105C26	Dehydrogenase
HOO69_15125	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
HOO69_15130	ENOG4105YP7	UPF0270 protein
HOO69_15135	ENOG4105DNZ	Alpha Beta Hydrolase
HOO69_15145	ENOG4105C5H	ABC transporter
HOO69_15150	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HOO69_15160	ENOG4105VKU	nucleicacid-binding protein
HOO69_15165	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HOO69_15170	ENOG4105D44	asparaginase
HOO69_15175	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HOO69_15180	ENOG4108UV7	flagellar protein motX
HOO69_15185	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HOO69_15190	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HOO69_15195	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HOO69_15200	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HOO69_15205	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HOO69_15210	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HOO69_15215	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HOO69_15220	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HOO69_15230	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HOO69_15235	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HOO69_15240	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HOO69_15245	ENOG41083MP	50s ribosomal protein l29
HOO69_15255	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HOO69_15260	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HOO69_15265	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HOO69_15270	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HOO69_15275	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HOO69_15280	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HOO69_15290	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HOO69_15295	ENOG4105VPB	50S ribosomal protein L30
HOO69_15300	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HOO69_15305	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HOO69_15315	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HOO69_15320	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HOO69_15325	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HOO69_15330	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HOO69_15335	ENOG4108ZT0	50S ribosomal protein l17
HOO69_15345	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HOO69_15360	ENOG4107YB6	acetyltransferase, (GNAT) family
HOO69_15365	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HOO69_15370	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
HOO69_15375	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HOO69_15380	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HOO69_15385	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HOO69_15395	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HOO69_15405	ENOG4105MYN	Zinc uptake regulation protein
HOO69_15410	ENOG4105BZU	Histidine kinase
HOO69_15415	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HOO69_15420	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HOO69_15440	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HOO69_15450	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HOO69_15505	ENOG4107RE3	peptidase, S41
HOO69_15540	ENOG4105BZU	Histidine kinase
HOO69_15580	ENOG4105EE0	oxidoreductase
HOO69_15595	ENOG4105KME	endoribonuclease L-psp
HOO69_15605	ENOG4108I5U	Uridine phosphorylase
HOO69_15610	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
HOO69_15630	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HOO69_15675	ENOG4105DDI	hemolysin-type calcium-binding region
HOO69_15680	ENOG4108JJA	ABC, transporter
HOO69_15685	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HOO69_15690	ENOG4108JJA	ABC, transporter
HOO69_15700	ENOG4105HEI	LysR family (Transcriptional regulator
HOO69_15710	ENOG4105Y7M	Transcriptional regulator, TetR family
HOO69_15730	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_15740	ENOG4107QZV	Type I secretion membrane fusion protein
HOO69_15745	ENOG4105BZ1	(ABC) transporter
HOO69_15750	ENOG4105BZ1	(ABC) transporter
HOO69_15785	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HOO69_15790	ENOG4105EB3	Histidine kinase
HOO69_15795	ENOG4105CT7	inner membrane cred family protein
HOO69_15810	ENOG4105DND	Transcriptional regulator
HOO69_15825	ENOG4108M3R	transcriptional activator CadC
HOO69_15865	ENOG4108JJA	ABC, transporter
HOO69_15870	ENOG4105E7U	AraC family transcriptional regulator
HOO69_15885	ENOG4105W5Q	DNA repair protein (RadC
HOO69_16045	ENOG4105HHM	rdd domain containing protein
HOO69_16055	ENOG4105C7K	acetolactate synthase
HOO69_16080	ENOG41082JN	Transcriptional regulator
HOO69_16085	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HOO69_16095	ENOG4105CH6	catalase
HOO69_16110	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HOO69_16120	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HOO69_16200	ENOG4105DXB	Major Facilitator superfamily
HOO69_16235	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HOO69_16240	ENOG4108V1U	phospholipid-binding protein
HOO69_16260	ENOG4105CIC	tryptophan-specific transport protein
HOO69_16320	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HOO69_16345	ENOG4108UW8	fha domain-containing protein
HOO69_16415	ENOG4108TU9	TRANSCRIPTIONal
HOO69_16435	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HOO69_16440	ENOG4105C26	Dehydrogenase
HOO69_16455	ENOG4105DHT	Metal Dependent Phosphohydrolase
HOO69_16510	ENOG4105JQN	Transcriptional regulator
HOO69_16530	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HOO69_16535	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HOO69_16545	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HOO69_16565	ENOG4105BZU	Histidine kinase
HOO69_16570	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
HOO69_16575	ENOG4107QWE	)-transporter
HOO69_16580	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HOO69_16585	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HOO69_16590	ENOG4105IBP	Cyclic peptide transporter
HOO69_16595	ENOG4105CUJ	penicillin amidase
HOO69_16640	ENOG4105DG4	malate L-lactate dehydrogenase
HOO69_16665	ENOG4105CJN	penicillin-binding protein
HOO69_16685	ENOG4105K4U	addiction module toxin, RelE StbE family
HOO69_16810	ENOG4105BZU	Histidine kinase
HOO69_16850	ENOG4108IJ9	(ABC) transporter
HOO69_16855	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
HOO69_16880	ENOG4105ETT	transcriptional Regulator, LysR family
HOO69_16895	ENOG4105CNH	Multidrug resistance protein MdtL
HOO69_16900	ENOG4105T0Z	Conserved Protein
HOO69_16915	ENOG4105C3R	Methionine synthase
HOO69_16920	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HOO69_16945	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_16950	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HOO69_16955	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
HOO69_16960	ENOG4105BZU	Histidine kinase
HOO69_16965	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_16970	ENOG4108V3W	Chemotaxis protein, CheW
HOO69_16975	ENOG4108V3W	Chemotaxis protein, CheW
HOO69_16980	ENOG4105CBS	Chea signal transduction histidine kinase
HOO69_16985	ENOG4108VYJ	response regulator receiver protein
HOO69_16995	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HOO69_17000	ENOG4106RMF	ParB family
HOO69_17025	ENOG4108JQ7	(ABC) transporter
HOO69_17045	ENOG4105CDY	transcriptional regulatory protein
HOO69_17065	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HOO69_17075	ENOG4105KVH	Transcriptional regulator
HOO69_17090	ENOG4105N0V	mono-oxygenase ydhR
HOO69_17095	ENOG4105C5Q	Transcriptional regulator
HOO69_17100	ENOG4108UW5	maltose o-acetyltransferase
HOO69_17105	ENOG4105VEQ	Cold shock protein
HOO69_17115	ENOG4105VYW	UPF0251 protein
HOO69_17130	ENOG4107653	Transcriptional regulator
HOO69_17150	ENOG4108KTG	Membrane protein, drug metabolite transporter
HOO69_17180	ENOG4105IJJ	transcriptional regulator, crp fnr family
HOO69_17185	ENOG4108RAV	Conserved protein
HOO69_17195	ENOG4108ZT1	Transcriptional regulator
HOO69_17205	ENOG4107QP3	malate synthase g
HOO69_17210	ENOG41060W2	glyoxylate carboligase
HOO69_17220	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HOO69_17225	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
HOO69_17230	ENOG4107QQ0	gntp family
HOO69_17235	ENOG4105BZW	Glycerate kinase
HOO69_17280	ENOG4105EFZ	amidohydrolase
HOO69_17285	ENOG4105EGI	Transcriptional regulator
HOO69_17295	ENOG4108RCM	Nitroreductase
HOO69_17300	ENOG4108M6U	Universal stress protein A
HOO69_17335	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HOO69_17340	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HOO69_17355	ENOG4105CJN	penicillin-binding protein
HOO69_17375	ENOG4105DUM	transcriptional regulator, lysR family
HOO69_17390	ENOG4108YI8	ABC transporter
HOO69_17395	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
HOO69_17400	ENOG4107Z6I	Thiamine biosynthesis protein
HOO69_17405	ENOG4105ETU	transcriptional activator (TenA
HOO69_17410	ENOG410620I	Diguanylate cyclase
HOO69_17415	ENOG4105EYK	Phosphatidylglycerophosphatase B
HOO69_17440	ENOG4105EJC	lysr family transcriptional regulator
HOO69_17475	ENOG4105DR5	peptidase
HOO69_17485	ENOG4105CPQ	Dehydrogenase
HOO69_17505	ENOG410904A	RNA polymerase
HOO69_17580	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HOO69_17585	ENOG4105WJG	Glutathione
HOO69_17605	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HOO69_17615	ENOG4105PDP	Short chain dehydrogenase
HOO69_17620	ENOG4105C8P	)-transporter
HOO69_17625	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
HOO69_17630	ENOG4105CKI	cobalamin synthesis protein
HOO69_17635	ENOG4105CD3	dihydroorotase
HOO69_17645	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HOO69_17665	ENOG4105F27	Major Facilitator
HOO69_17670	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HOO69_17675	ENOG4105C26	Dehydrogenase
HOO69_17680	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_17700	ENOG4108YYI	Protein of unknown function (DUF2810)
HOO69_17705	ENOG4105DW5	Transcriptional regulator
HOO69_17710	ENOG410667J	hydrolase
HOO69_17720	ENOG4108JB8	alcohol dehydrogenase
HOO69_17725	ENOG4107YBY	Hydrolase
HOO69_17735	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HOO69_17745	ENOG4107QSE	Dipeptidase
HOO69_17760	ENOG4105E0U	tyrosine-specific transport protein
HOO69_17765	ENOG41061ZR	Transcriptional regulator
HOO69_17770	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
HOO69_17775	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
HOO69_17780	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
HOO69_17795	ENOG4108YZN	class I peptide chain release factor
HOO69_17810	ENOG4108SGD	regulatory protein
HOO69_17860	ENOG4105EUB	pirin domain protein
HOO69_17880	ENOG4105BZ1	(ABC) transporter
HOO69_17895	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HOO69_17910	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
HOO69_17915	ENOG4105J76	Periplasmic binding protein
HOO69_17920	ENOG4105E0A	ABC, transporter
HOO69_17925	ENOG4105C6X	Major Facilitator
HOO69_17940	ENOG4105D6U	Sodium Glutamate Symporter
HOO69_17945	ENOG4105YE1	PilZ domain
HOO69_17960	ENOG4105WCN	acetyltransferase
HOO69_17970	ENOG4105EP9	oxidoreductase
HOO69_17975	ENOG4105EXG	Transcriptional regulator
HOO69_17980	ENOG4105CDH	Citrulline--aspartate ligase
HOO69_18030	ENOG4105DHQ	Histidine kinase
HOO69_18035	ENOG4105ETX	regulatoR
HOO69_18060	ENOG4105BZS	acriflavin resistance protein
HOO69_18075	ENOG4106NZI	LysR family Transcriptional regulator
HOO69_18080	ENOG4105DWD	nucleoside recognition domain protein
HOO69_18105	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
HOO69_18120	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HOO69_18125	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
HOO69_18135	ENOG4106CKV	Pap2 superfamily protein
HOO69_18145	ENOG4105DKT	Transcriptional regulator
HOO69_18150	ENOG4105CBT	Fructose-1,6-bisphosphatase
HOO69_18155	ENOG4108YZG	isomerase
HOO69_18160	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HOO69_18170	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HOO69_18175	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HOO69_18180	ENOG4105CMT	Dihydroxyacetone kinase
HOO69_18185	ENOG4108UTZ	Dihydroxyacetone kinase
HOO69_18195	ENOG4105RK9	auxin efflux carrier
HOO69_18210	ENOG4108JUA	Transcriptional regulator
HOO69_18240	ENOG41061CK	Antibiotic biosynthesis monooxygenase
HOO69_18255	ENOG4105E89	ABC transporter
HOO69_18260	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HOO69_18265	ENOG4105ETT	transcriptional Regulator, LysR family
HOO69_18280	ENOG4105C2C	drug resistance transporter, Bcr CflA
HOO69_18285	ENOG4105CE4	GlcNAc 6-P deacetylase
HOO69_18290	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
HOO69_18295	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
HOO69_18300	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
HOO69_18305	ENOG41069H7	transport system small permease component
HOO69_18310	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HOO69_18320	ENOG4105QEK	Transcriptional regulator
HOO69_18325	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
HOO69_18330	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
HOO69_18335	ENOG4108478	ec 3.2.1.18
HOO69_18340	ENOG4105BZU	Histidine kinase
HOO69_18350	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
HOO69_18355	ENOG4107W52	maltose operon periplasmic protein
HOO69_18370	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HOO69_18380	ENOG4105D03	DNA-3-methyladenine glycosylase II
HOO69_18385	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HOO69_18395	ENOG4105DN9	Na H antiporter
HOO69_18400	ENOG41074DU	domain protein
HOO69_18405	ENOG4108P2H	Inner membrane protein YjiG
HOO69_18410	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HOO69_18415	ENOG4105DQS	Transcriptional regulator
HOO69_18430	ENOG4105E0K	tonB-dependent siderophore receptor
HOO69_18460	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HOO69_18475	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HOO69_18480	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HOO69_18490	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
HOO69_18500	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HOO69_18505	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
HOO69_18510	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HOO69_18530	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HOO69_18535	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HOO69_18545	ENOG4105E5Q	amino acid AbC transporter
HOO69_18550	ENOG4106TNF	Periplasmic binding protein
HOO69_18555	ENOG4105E5Q	amino acid AbC transporter
HOO69_18560	ENOG4105CDA	abc transporter atp-binding protein
HOO69_18565	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HOO69_18575	ENOG4108IJ7	Glycine betaine
HOO69_18580	ENOG4108HQS	Glycine betaine
HOO69_18625	ENOG4107U53	septum site-determining protein minD
HOO69_18680	ENOG4105CJ2	(LipO)protein
HOO69_18685	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HOO69_18690	ENOG4107RGH	Aldehyde dehydrogenase
HOO69_18695	ENOG4105EXG	Transcriptional regulator
HOO69_18700	ENOG4105EMU	Dehydrogenase
HOO69_18715	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HOO69_18730	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HOO69_18755	ENOG4105DHT	Metal Dependent Phosphohydrolase
HOO69_18760	ENOG41068P6	UPF0319 protein
HOO69_18765	ENOG4105C0F	tryptophanase EC 4.1.99.1
HOO69_18790	ENOG4107QZV	Type I secretion membrane fusion protein
HOO69_18795	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HOO69_18805	ENOG4105E6M	Sulphatase-modifying factor protein
HOO69_18830	ENOG4105CK7	Sodium proline symporter
HOO69_18840	ENOG4105EW9	transcriptional regulator AsnC family
HOO69_18860	ENOG4108N3W	hemolysin secretion protein
HOO69_18865	ENOG4105I4A	GCN5-related N-acetyltransferase
HOO69_18880	ENOG4105RA2	Membrane
HOO69_18890	ENOG4108JJB	ABC transporter
HOO69_18895	ENOG4108V7D	UPF0397 protein
HOO69_18900	ENOG4105EFX	secretion protein, HlyD family
HOO69_18905	ENOG4105KK7	inner membrane protein YiaW
HOO69_18910	ENOG4106TD9	Diguanylate cyclase
HOO69_18925	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
HOO69_18930	ENOG4107SEY	Conserved Protein
HOO69_18935	ENOG4108XDN	Transcriptional regulator
HOO69_18940	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HOO69_18945	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HOO69_18955	ENOG4105C1J	atp-dependent rna helicase
HOO69_18965	ENOG4105C1J	atp-dependent rna helicase
HOO69_18970	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
HOO69_18985	ENOG4105CVA	phosphate
HOO69_18995	ENOG4107QX8	SPFH domain, Band 7 family protein
HOO69_19005	ENOG4105CT4	transporter
HOO69_19010	ENOG4105F8D	glycoside hydrolase family 4
HOO69_19015	ENOG4108K2B	transcriptional regulator
HOO69_19020	ENOG4108IJ9	(ABC) transporter
HOO69_19025	ENOG4107FKK	extracellular solute-binding protein family 1
HOO69_19030	ENOG4105D56	permease protein
HOO69_19075	ENOG4105BZU	Histidine kinase
HOO69_19080	ENOG4107YWA	deoxycytidylate deaminase
HOO69_19085	ENOG4105DZC	cytosine deaminase
HOO69_19090	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
HOO69_19095	ENOG4105CJW	magnesium transporter
HOO69_19100	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HOO69_19135	ENOG4105DVH	amino acid
HOO69_19140	ENOG4105EW9	transcriptional regulator AsnC family
HOO69_19155	ENOG4105EE0	oxidoreductase
HOO69_19160	ENOG4108UKZ	OsmC family
HOO69_19195	ENOG4107QVM	von Willebrand factor, type A
HOO69_19210	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HOO69_19215	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_19230	ENOG4105HEI	LysR family (Transcriptional regulator
HOO69_19255	ENOG4105BZU	Histidine kinase
HOO69_19270	ENOG4105QVC	MOSC domain-containing protein
HOO69_19270	ENOG4105QVC	MOSC domain-containing protein
HOO69_19275	ENOG4105BZU	Histidine kinase
HOO69_19290	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
HOO69_19295	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HOO69_19305	ENOG4108JQ5	ABC transporter
HOO69_19325	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_19340	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
HOO69_19345	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HOO69_19355	ENOG4105BZU	Histidine kinase
HOO69_19360	ENOG4105EQ2	LysR family Transcriptional regulator
HOO69_19365	ENOG4105E5M	Multidrug resistance protein D
HOO69_19385	ENOG4108SXK	Transporter Drug Metabolite Exporter family
HOO69_19405	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HOO69_19420	ENOG4108JUA	Transcriptional regulator
HOO69_19425	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HOO69_19440	ENOG4105VEQ	Cold shock protein
HOO69_19460	ENOG4105DZ1	carboxypeptidase
HOO69_19465	ENOG4108M1A	Chitin-binding protein
HOO69_19480	ENOG4105VRT	cytoplasmic protein
HOO69_19495	ENOG4105CHP	RNA polymerase
HOO69_19500	ENOG4105GRZ	Ycii-related protein
HOO69_19505	ENOG4105C0A	alcohol dehydrogenase
HOO69_19510	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
HOO69_19515	ENOG4105JQN	Transcriptional regulator
HOO69_19520	ENOG4105PAD	Hydrolase
HOO69_19545	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HOO69_19550	ENOG4108JPW	Aminotransferase
HOO69_19555	ENOG4107STF	Involved in phosphonate degradation (By similarity)
HOO69_19575	ENOG4107RCV	ABC transporter, permease
HOO69_19605	ENOG4105CJP	fad dependent oxidoreductase
HOO69_19610	ENOG4105ETT	transcriptional Regulator, LysR family
HOO69_19615	ENOG4105EJQ	L-serine dehydratase
HOO69_19635	ENOG4106TD9	Diguanylate cyclase
HOO69_19645	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
HOO69_19650	ENOG4105CGH	5'-nucleotidase
HOO69_19655	ENOG4106RE7	Cytochrome
HOO69_19665	ENOG4108YZ4	nudix hydrolase
HOO69_19675	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
HOO69_19680	ENOG4105E5M	Multidrug resistance protein D
HOO69_19695	ENOG4105EW9	transcriptional regulator AsnC family
HOO69_19700	ENOG41064RH	membrane protein YliF
HOO69_19705	ENOG41067TZ	transcriptional regulator, MarR family
HOO69_19710	ENOG4105C94	Transporter
HOO69_19715	ENOG4108IRC	dna polymerase iii
HOO69_19725	ENOG4105CKU	formyltetrahydrofolate synthetase
HOO69_19755	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HOO69_19760	ENOG410804D	Sensor Signal Transduction Histidine Kinase
HOO69_19770	ENOG4105F2V	VRR-NUC domain-containing protein
HOO69_19785	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
HOO69_19790	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HOO69_19795	ENOG4105BZJ	Electron transfer flavoprotein
HOO69_19800	ENOG4105C10	Electron transfer flavoprotein
HOO69_19805	ENOG4108N3W	hemolysin secretion protein
HOO69_19810	ENOG4107QSN	dihydrolipoamide acetyltransferase
HOO69_19815	ENOG4105CPP	Dehydrogenase, E1 component
HOO69_19820	ENOG4107RUY	(E1 component), alpha subunit
HOO69_19825	ENOG4105BZG	amino acid carrier protein
HOO69_19840	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_19845	ENOG4105BZU	Histidine kinase
HOO69_19865	ENOG4105BZU	Histidine kinase
HOO69_19875	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HOO69_19880	ENOG41060WC	Enoyl-CoA hydratase
HOO69_19885	ENOG4107QX3	carboxylase
HOO69_19890	ENOG4105C1G	acyl-Coa dehydrogenase
HOO69_19900	ENOG4105CHU	acetyl-coa acetyltransferase
HOO69_19905	ENOG4105C26	Dehydrogenase
HOO69_19910	ENOG4105C1G	acyl-Coa dehydrogenase
HOO69_19915	ENOG4105E39	Enoyl-CoA hydratase
HOO69_19920	ENOG4105E39	Enoyl-CoA hydratase
HOO69_19925	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HOO69_19930	ENOG4105CHR	reductase
HOO69_19935	ENOG4108N3W	hemolysin secretion protein
HOO69_19945	ENOG4105MSB	protein, conserved in bacteria
HOO69_19955	ENOG4105CBN	LysR family transcriptional regulator
HOO69_19960	ENOG4105CXG	d-lactate dehydrogenase
HOO69_19975	ENOG4105BZU	Histidine kinase
HOO69_19995	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HOO69_20000	ENOG4107QYG	anthranilate phosphoribosyltransferase
HOO69_20015	ENOG4105DG7	nitrate ABC transporter
HOO69_20020	ENOG4105D7T	ABC transporter
HOO69_20025	ENOG4107QZF	nitrite reductase NADPH large subunit
HOO69_20030	ENOG4105WZK	nitrite reductase NADPH small subunit
HOO69_20035	ENOG4105WH1	Two component transcriptional regulator luxr family
HOO69_20045	ENOG4105BZU	Histidine kinase
HOO69_20075	ENOG4105VXR	cytoplasmic protein
HOO69_20085	ENOG4105K63	Thioredoxin
HOO69_20090	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HOO69_20095	ENOG4107RFY	SbcCD D subunit
HOO69_20100	ENOG4105EYH	Exonuclease
HOO69_20105	ENOG4108MGY	Histidine kinase
HOO69_20110	ENOG4107KBT	8-Amino-7-oxononanoate synthase
HOO69_20120	ENOG4105CMQ	Chloride channel
HOO69_20125	ENOG4105CKI	cobalamin synthesis protein
HOO69_20130	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
HOO69_20140	ENOG4105E3R	(LipO)protein
HOO69_20150	ENOG4108Y9B	(LipO)protein
HOO69_20160	ENOG4107V1M	polysaccharide export protein
HOO69_20170	ENOG4105C2X	Arabinose 5-phosphate isomerase
HOO69_20175	ENOG41090SZ	ABC-2 type transporter
HOO69_20195	ENOG4105E12	capsule polysaccharide
HOO69_20205	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HOO69_20210	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HOO69_20215	ENOG4105ESV	Glycosyl transferase, family 4
HOO69_20230	ENOG4105C8Y	Acetylornithine aminotransferase
HOO69_20255	ENOG4105KNY	Microcompartments protein
HOO69_20270	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HOO69_20275	ENOG4105E43	Extracellular solute-binding protein, family 5
HOO69_20280	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HOO69_20285	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HOO69_20290	ENOG4108JQ5	ABC transporter
HOO69_20300	ENOG4108K0B	C-di-gmp phosphodiesterase
HOO69_20310	ENOG4108Q9V	regulatoR
HOO69_20330	ENOG4105DHS	permease protein
HOO69_20335	ENOG4105CM4	permease protein
HOO69_20340	ENOG4108IPW	abc transporter atp-binding protein
HOO69_20345	ENOG4108Z6Z	Transcriptional regulator
HOO69_20365	ENOG4105BZU	Histidine kinase
HOO69_20370	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HOO69_20490	ENOG4105KK4	UPF0060 membrane protein
HOO69_20555	ENOG4105KAF	membrAne
HOO69_20575	ENOG4105D9U	N-acetyltransferase
HOO69_20610	ENOG4108K3A	Glutathione S-transferase
HOO69_20635	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HOO69_20660	ENOG4108IG5	Transcriptional regulator
HOO69_20665	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HOO69_20685	ENOG4105CHU	acetyl-coa acetyltransferase
HOO69_20695	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HOO69_20705	ENOG4105DXI	Major Facilitator superfamily
HOO69_20710	ENOG4105KUU	lipolytic protein G-D-S-L family
HOO69_20790	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HOO69_20795	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HOO69_20800	ENOG4105CGF	Aromatic amino acid aminotransferase
HOO69_20805	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HOO69_20810	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HOO69_20815	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HOO69_20825	ENOG4105CDV	Ompa motb domain protein
HOO69_20830	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HOO69_20840	ENOG41090HJ	UPF0265 protein
HOO69_20850	ENOG4108YXG	UPF0502 protein
HOO69_20855	ENOG41082IR	Excinuclease ABC C subunit domain protein
HOO69_20870	ENOG4105BZU	Histidine kinase
HOO69_20890	ENOG4105EM2	membrane
HOO69_20895	ENOG41088T4	Helicase IV
HOO69_20915	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HOO69_20925	ENOG4105E2Y	ABC, transporter
HOO69_20930	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HOO69_20935	ENOG4108MK9	spermidine N(1)-acetyltransferase
HOO69_20950	ENOG4105RKW	reductase (By
HOO69_20960	ENOG4108I0Y	(ABC) transporter
HOO69_20975	ENOG4107R7A	Allophanate hydrolase subunit 2
HOO69_20985	ENOG4105E7W	lamb ycsf family protein
HOO69_20990	ENOG4105BZU	Histidine kinase
HOO69_20995	ENOG4105CMR	udp-glucose 4-epimerase
HOO69_21015	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HOO69_21025	ENOG4108ZNS	ferredoxin-type protein NapF
HOO69_21030	ENOG4105BZU	Histidine kinase
HOO69_21035	ENOG4105WH1	Two component transcriptional regulator luxr family
HOO69_21040	ENOG4105CEE	C4-dicarboxylate transporter
HOO69_21065	ENOG4105DS1	cytochrome b561
HOO69_21070	ENOG4108YYC	ycei family
HOO69_21075	ENOG4105TMB	Formate nitrite transporter
HOO69_21080	ENOG4105DUM	transcriptional regulator, lysR family
HOO69_21085	ENOG4108UQ5	membrane protein YcdZ
HOO69_21090	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
HOO69_21095	ENOG4105CGH	5'-nucleotidase
HOO69_21100	ENOG4105DU1	integral membrane protein, terc
HOO69_21125	ENOG4105DZP	Membrane-associated zinc metalloprotease
HOO69_21130	ENOG4105ERG	peptidase m48, ste24p
HOO69_21135	ENOG4105KA0	thioesterase Superfamily protein
HOO69_21155	ENOG4108MVK	Receptor
HOO69_21160	ENOG4105CWB	LysR family transcriptional Regulator
HOO69_21170	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HOO69_21175	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
HOO69_21180	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
HOO69_21190	ENOG4105DHT	Metal Dependent Phosphohydrolase
HOO69_21195	ENOG4107SSZ	Phosphatase
HOO69_21215	ENOG4105EXG	Transcriptional regulator
HOO69_21220	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HOO69_21225	ENOG4105CPQ	Dehydrogenase
HOO69_21260	ENOG4105D9N	nucleoside
HOO69_21265	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HOO69_21290	ENOG4105D6J	arsenicaL-resistance protein
HOO69_21300	ENOG4105CD5	CoA-binding domain protein
HOO69_21310	ENOG4105CPF	Cell wall formation (By similarity)
HOO69_21325	ENOG4108ZJT	translation initiation factor, Sui1
HOO69_21500	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HOO69_21510	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HOO69_21515	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HOO69_21530	ENOG4105BZU	Histidine kinase
HOO69_21545	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
HOO69_21550	ENOG4105E0C	molybdate abc transporter
HOO69_21555	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HOO69_21560	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HOO69_21565	ENOG4105WXI	Bacterial OB fold (BOF) protein
HOO69_21575	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
HOO69_21580	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
HOO69_21585	ENOG4105DE4	1-phosphofructokinase
HOO69_21590	ENOG4105DM4	PTS System
HOO69_21595	ENOG4105BZU	Histidine kinase
HOO69_21600	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HOO69_21610	ENOG4105CF7	AraC family transcriptional regulator
HOO69_21615	ENOG4108I6A	alcohol dehydrogenase
HOO69_21630	ENOG4105BZU	Histidine kinase
HOO69_21635	ENOG4108SV3	Tmao reductase system periplasmic protein tort
HOO69_21640	ENOG4108Z5K	methylglyoxal synthase
HOO69_21650	ENOG4107XGZ	Hydrolase
HOO69_21665	ENOG4107RE1	Inosine-guanosine kinase
HOO69_21670	ENOG4107VXZ	Hydrolase
HOO69_21715	ENOG4105C1J	atp-dependent rna helicase
HOO69_21725	ENOG4105E0U	tyrosine-specific transport protein
HOO69_21730	ENOG4105E0X	reductase
HOO69_21745	ENOG4105C1J	atp-dependent rna helicase
HOO69_21750	ENOG4105EUJ	GTP cyclohydrolase i
HOO69_21755	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HOO69_21760	ENOG4105D06	uba thif-type nad fad binding protein
HOO69_21770	ENOG4108NVR	Methyl-accepting chemotaxis
HOO69_21775	ENOG4105KHC	sulfurtransferase
HOO69_21865	ENOG4105HEI	LysR family (Transcriptional regulator
HOO69_21875	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HOO69_21885	ENOG4105FKN	transcriptional regulator, AsnC family
HOO69_21890	ENOG4105HKU	nucleoside recognition domain-containing protein
HOO69_21900	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_21910	ENOG4105C5I	Dehydrogenase
HOO69_21915	ENOG4105DAN	ATP-dependent protease
HOO69_21925	ENOG4108JQ5	ABC transporter
HOO69_21935	ENOG4105CR8	Transcriptional regulator
HOO69_21940	ENOG4105DAA	L-lactate
HOO69_21945	ENOG4105DMF	Dehydrogenase
HOO69_21950	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HOO69_21965	ENOG4107ZF2	Phosphatase
HOO69_22005	ENOG4105K64	Glycosyl transferase, family 2
HOO69_22015	ENOG4105D75	Capsular exopolysaccharide family
HOO69_22030	ENOG4105D3Q	Sugar transferase
HOO69_22050	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
HOO69_22055	ENOG4105C26	Dehydrogenase
HOO69_22105	ENOG4108IJ7	Glycine betaine
HOO69_22120	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
HOO69_22125	ENOG4105C26	Dehydrogenase
HOO69_22130	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HOO69_22135	ENOG4105BZU	Histidine kinase
HOO69_22140	ENOG4108VYJ	response regulator receiver protein
HOO69_22150	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
HOO69_22160	ENOG4105E0K	tonB-dependent siderophore receptor
HOO69_22175	ENOG4105WQT	MbtH domain protein
HOO69_22180	ENOG4105IBP	Cyclic peptide transporter
HOO69_22185	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
HOO69_22190	ENOG4105J76	Periplasmic binding protein
HOO69_22195	ENOG4105E0A	ABC, transporter
HOO69_22235	ENOG4105FDK	ABC transporter
HOO69_22240	ENOG41080V6	ABC-3 protein
HOO69_22250	ENOG4105E0K	tonB-dependent siderophore receptor
HOO69_22280	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HOO69_22295	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HOO69_22300	ENOG4108NVR	Methyl-accepting chemotaxis
HOO69_22310	ENOG4105EW9	transcriptional regulator AsnC family
HOO69_22320	ENOG4105Q26	Siderophore-interacting protein
HOO69_22325	ENOG4105CC0	LysR family Transcriptional regulator
HOO69_22335	ENOG4105D3G	Pseudouridine synthase
HOO69_22360	ENOG4105C1J	atp-dependent rna helicase
HOO69_22365	ENOG4105V0I	UPF0267 protein
HOO69_22370	ENOG4105BZU	Histidine kinase
HOO69_22375	ENOG4108WUH	Transcriptional regulator, TetR family
HOO69_22380	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HOO69_22390	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HOO69_22395	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HOO69_22415	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
HOO69_22420	ENOG4105CYM	Glutathione S-transferase
HOO69_22430	ENOG4105C9Q	fumarate hydratase class II
HOO69_22450	ENOG4105BZU	Histidine kinase
HOO69_22480	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HOO69_22520	ENOG4105BZU	Histidine kinase
HOO69_22545	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HOO69_22550	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HOO69_22595	ENOG4105KHS	type IV fimbrial pilin protein
HOO69_22600	ENOG4105NXV	High-affinity zinc uptake system protein
HOO69_22615	ENOG4107W31	Pentapeptide repeat protein
HOO69_22620	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HOO69_22640	ENOG4108Z4X	TRANSCRIPTIONal
HOO69_22665	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_22670	ENOG4105R8A	Heat shock protein
HOO69_22685	ENOG4107S8C	mandelate racemase muconate lactonizing
HOO69_22705	ENOG4107R28	alpha amylase, catalytic region
HOO69_22710	ENOG4107FKK	extracellular solute-binding protein family 1
HOO69_22720	ENOG4105CG3	alpha amylase, catalytic region
HOO69_22730	ENOG4108VAC	response regulator
HOO69_22735	ENOG4108HRK	Histidine kinase
HOO69_22750	ENOG4105D60	lipoprotein releasing system transmembrane protein
HOO69_22755	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HOO69_22770	ENOG4105KME	endoribonuclease L-psp
HOO69_22775	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HOO69_22780	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HOO69_22810	ENOG4105BZU	Histidine kinase
HOO69_22825	ENOG4105MIR	Phenylalanine 4-monooxygenase
HOO69_22830	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HOO69_22840	ENOG4105EGI	Transcriptional regulator
HOO69_22850	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
HOO69_22865	ENOG4105E09	nadh pyrophosphatase
HOO69_22870	ENOG4105DXX	methyltransferase
HOO69_22890	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HOO69_22895	ENOG41082NX	50s ribosomal protein l35
HOO69_22900	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HOO69_22905	ENOG4105C22	threonyL-tRNA synthetase
HOO69_22910	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HOO69_22925	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HOO69_22930	ENOG4105BZU	Histidine kinase
HOO69_22940	ENOG4108ZBE	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition (By similarity)
HOO69_22950	ENOG4107MMM	Anti-sigma-factor antagonist
HOO69_22955	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HOO69_22995	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HOO69_23005	ENOG4108WBT	adenosyltransferase
HOO69_23010	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
HOO69_23015	ENOG41090JE	Utilization Protein
HOO69_23025	ENOG4105WQ5	TonB family
HOO69_23030	ENOG41090AP	transport protein
HOO69_23035	ENOG4106GFD	transport protein
HOO69_23045	ENOG4105EHG	Permease protein
HOO69_23050	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HOO69_23060	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HOO69_23070	ENOG4105EIF	outer membrane protein W
HOO69_23075	ENOG4105DR5	peptidase
HOO69_23100	ENOG4105DWD	nucleoside recognition domain protein
HOO69_23110	ENOG410620I	Diguanylate cyclase
HOO69_23115	ENOG4105P8Q	Curli production assembly transport component CsgG
HOO69_23150	ENOG4105E2Z	phosphate ABC transporter (Permease
HOO69_23155	ENOG4105C8U	phosphate abc transporter
HOO69_23165	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_23180	ENOG4107R88	Chemotaxis protein (CheV)
HOO69_23190	ENOG4105BZU	Histidine kinase
HOO69_23195	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HOO69_23200	ENOG4105ETE	Transcriptional regulator (LacI family
HOO69_23205	ENOG4108RVA	ribokinase
HOO69_23210	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
HOO69_23215	ENOG4105CNN	ABC, transporter
HOO69_23220	ENOG4105C2J	ABC transporter
HOO69_23225	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
HOO69_23240	ENOG41086KC	Transcriptional regulator
HOO69_23255	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HOO69_23270	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HOO69_23275	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HOO69_23285	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HOO69_23305	ENOG4105BZU	Histidine kinase
HOO69_23330	ENOG4108JCI	Transcriptional regulator
HOO69_23345	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
HOO69_23350	ENOG4108WC9	type VI secretion system effector, hcp1 family
HOO69_23355	ENOG4105CS6	Rhs element vgr protein
HOO69_23415	ENOG4105DIQ	Transcriptional regulator
HOO69_23420	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
HOO69_23425	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HOO69_23430	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HOO69_23435	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
HOO69_23440	ENOG4105CH5	extracellular solute-binding protein, family 7
HOO69_23450	ENOG4105BZU	Histidine kinase
HOO69_23470	ENOG4105BZU	Histidine kinase
HOO69_23480	ENOG4107G43	radical SAM domain protein
HOO69_23490	ENOG4105NBK	UPF0345 protein
HOO69_23500	ENOG4105D64	Mechanosensitive ion channel
HOO69_23505	ENOG4105E5W	Transporter
HOO69_23520	ENOG4107T9C	Alpha amylase catalytic region
HOO69_23575	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HOO69_23580	ENOG4105CQZ	Histidine kinase
HOO69_23590	ENOG4105DQF	Hydrolase
HOO69_23595	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
HOO69_23610	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
HOO69_23650	ENOG4108UZ3	Transporter
HOO69_23655	ENOG4105EJC	lysr family transcriptional regulator
HOO69_23685	ENOG4105BZU	Histidine kinase
HOO69_23690	ENOG4105C5H	ABC transporter
HOO69_23695	ENOG4105GXZ	Ferredoxin-type protein NapH
HOO69_23700	ENOG4108BGM	Quinol dehydrogenase periplasmic component
HOO69_23705	ENOG4108IEG	Formate dehydrogenase Alpha subunit
HOO69_23750	ENOG4105EWC	Purine nucleoside phosphorylase
HOO69_23775	ENOG4105CHU	acetyl-coa acetyltransferase
HOO69_23780	ENOG4105CHR	reductase
HOO69_23785	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
HOO69_23805	ENOG4105CH5	extracellular solute-binding protein, family 7
HOO69_23815	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HOO69_23830	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
HOO69_23855	ENOG4105BZU	Histidine kinase
HOO69_23860	ENOG4105BZU	Histidine kinase
HOO69_23870	ENOG4105S8Q	sugar efflux transporter
HOO69_23885	ENOG4105CIF	Ornithine Cyclodeaminase
HOO69_23895	ENOG4105CTU	Proline racemase
HOO69_23910	ENOG4105CI1	PTS System
HOO69_23920	ENOG4105DHQ	Histidine kinase
HOO69_23925	ENOG4108JP0	extracellular solute-binding protein family 1
HOO69_23935	ENOG4105BZU	Histidine kinase
HOO69_23960	ENOG4107QSI	ABC, transporter
HOO69_23965	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HOO69_23970	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HOO69_23975	ENOG4105C3U	ABC transporter
HOO69_23980	ENOG4108JQ7	(ABC) transporter
HOO69_23990	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HOO69_23995	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HOO69_24020	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
HOO69_24025	ENOG4105C6F	GntR Family Transcriptional Regulator
HOO69_24030	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HOO69_24035	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HOO69_24040	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HOO69_24045	ENOG4105DEI	Mannitol dehydrogenase
HOO69_24050	ENOG4105D2H	Uronic isomerase
HOO69_24055	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
HOO69_24060	ENOG4108UHU	Aldolase
HOO69_24065	ENOG4105P66	Membrane
HOO69_24105	ENOG4105KXC	Collagenase
HOO69_24120	ENOG4107MM9	BNR Asp-box repeat-containing protein
HOO69_24130	ENOG4105UBK	short-chain dehydrogenase reductase
HOO69_24150	ENOG4105DWP	Membrane
HOO69_24155	ENOG4105JQN	Transcriptional regulator
HOO69_24160	ENOG4108UPT	UPF0178 protein
HOO69_24170	ENOG4107RZC	phospholipase d
HOO69_24175	ENOG4105CK2	sodium dicarboxylate symporter
HOO69_24180	ENOG4108KMM	Diguanylate cyclase
HOO69_24215	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HOO69_24245	ENOG4105C84	Histidine ammonia-lyase
HOO69_24270	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HOO69_24275	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HOO69_24280	ENOG4105C2D	reductase
HOO69_24285	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HOO69_24290	ENOG4107QWR	cellulase (EC 3.2.1.4)
HOO69_24300	ENOG4105VEQ	Cold shock protein
HOO69_24305	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HOO69_24310	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HOO69_24315	ENOG4105CYW	agmatinase
HOO69_24320	ENOG4108ZX5	transcriptional regulator
HOO69_24345	ENOG4108NVR	Methyl-accepting chemotaxis
HOO69_24350	ENOG4105JXH	GntR family transcriptional regulator
HOO69_24370	ENOG4107QUY	Guanine deaminase
HOO69_24375	ENOG4105E89	ABC transporter
HOO69_24380	ENOG4105C8Q	Methyl-accepting chemotaxis
HOO69_24385	ENOG4105BZU	Histidine kinase
HOO69_24400	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HOO69_24415	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HOO69_24420	ENOG4105CQM	Urea amidohydrolase subunit alpha
HOO69_24425	ENOG4105KI2	Urea amidohydrolase subunit beta
HOO69_24430	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HOO69_24440	ENOG4108IV0	ABC, transporter
HOO69_24445	ENOG4105C0Z	ABC transporter
HOO69_24455	ENOG4105C32	Amino acid ABC transporter (Permease)
HOO69_24465	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HOO69_24475	ENOG41069D7	Methyl-accepting chemotaxis
HOO69_24485	ENOG4108Z2U	ureidoglycolate hydrolase
HOO69_24490	ENOG4105DHG	Allantoate amidinohydrolase
HOO69_24505	ENOG4105VT2	5-hydroxyisourate hydrolase
HOO69_24510	ENOG4105C7N	Xanthine uracil vitamin C permease
HOO69_24520	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HOO69_24530	ENOG4105EXG	Transcriptional regulator
HOO69_24540	ENOG4107U2T	alpha beta
HOO69_24575	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
HOO69_24580	ENOG4105ETE	Transcriptional regulator (LacI family
HOO69_24590	ENOG4105N14	lysine exporter protein LysE YggA
HOO69_24615	ENOG4105C26	Dehydrogenase
HOO69_24630	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HOO69_24635	ENOG4105EIP	mannose-6-phosphate isomerase
HOO69_24640	ENOG4105DM4	PTS System
HOO69_24650	ENOG4105C8I	hydrolase, family 38
HOO69_24655	ENOG4105DM4	PTS System
HOO69_24660	ENOG4106KNT	transcriptional regulator
HOO69_24675	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HOO69_24680	ENOG410901P	UPF0249 protein
HOO69_24690	ENOG4105C5H	ABC transporter
HOO69_24700	ENOG4107S76	domain protein
HOO69_24710	ENOG4105DZ0	fad dependent oxidoreductase
HOO69_24715	ENOG4108Z4U	Ferredoxin
HOO69_24725	ENOG4105KVH	Transcriptional regulator
HOO69_24735	ENOG4105K5X	acetyltransferase
HOO69_24755	ENOG4105EST	Metal Dependent Phosphohydrolase
HOO69_24765	ENOG4105G2Y	Transcriptional regulator
HOO69_24770	ENOG4105CNH	Multidrug resistance protein MdtL
HOO69_24790	ENOG4105S7S	phosphonate abc transporter
HOO69_24800	ENOG4105D5T	phosphonate abc transporter
HOO69_24830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HOO69_24835	ENOG4105CQZ	Histidine kinase
HOO69_24850	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HOO69_24860	ENOG4108J2P	Alpha beta hydrolase fold
HOO69_24865	ENOG4108M0I	Transcriptional regulator
HOO69_24870	ENOG4105CZN	Potassium uptake protein
HOO69_24890	ENOG4108NVR	Methyl-accepting chemotaxis
HOO69_24910	ENOG4105E2D	ec 3.2.1.52
HOO69_24915	ENOG4108UHU	Aldolase
HOO69_24925	ENOG4108IA2	Sodium pantothenate symporter
HOO69_24955	ENOG4105CZV	ABC transporter
HOO69_24960	ENOG4105FDP	GntR family transcriptional regulator
HOO69_24970	ENOG4105D2N	Aldolase
HOO69_24975	ENOG4105CE4	GlcNAc 6-P deacetylase
HOO69_24980	ENOG4108YTN	IIa component
HOO69_24985	ENOG4105F3R	pts system mannose fructose sorbose family iid
HOO69_24995	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
HOO69_25000	ENOG4105E70	isomerase
HOO69_25005	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
HOO69_25010	ENOG4105E98	transcriptional regulator DeoR family
HOO69_25015	ENOG4105E98	transcriptional regulator DeoR family
HOO69_25030	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HOO69_25065	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
HOO69_25085	ENOG4105CR4	methylisocitrate lyase
HOO69_25095	ENOG4107T8T	UPF0173 metal-dependent hydrolase
HOO69_25100	ENOG4105CZK	Aspartate kinase
HOO69_25105	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
HOO69_25110	ENOG4108JPW	Aminotransferase
HOO69_25115	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
HOO69_25125	ENOG4105E7U	AraC family transcriptional regulator
HOO69_25130	ENOG410829K	Lysine exporter protein (Lyse ygga)
HOO69_25135	ENOG4108XM1	transcriptional regulator AsnC family
HOO69_25145	ENOG4108RPX	mosc domain containing protein
HOO69_25150	ENOG41060NJ	transcriptional regulator
HOO69_25155	ENOG4105DFD	Na H antiporter
HOO69_25160	ENOG4105C87	Aminotransferase class I and II