locus-tag	class	description
KC397_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KC397_00010	COG0592	DNA-directed DNA polymerase activity
KC397_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KC397_00020	COG0187	DNA topoisomerase II activity
KC397_00025	COG0071	Belongs to the small heat shock protein (HSP20) family
KC397_00030	COG3977	Valine--pyruvate aminotransferase
KC397_00035	COG0751	glycine-tRNA ligase activity
KC397_00040	COG0752	glycyl-tRNA synthetase alpha subunit
KC397_00045	COG2119	membrane
KC397_00055	COG0425	Belongs to the sulfur carrier protein TusA family
KC397_00070	COG0604	alcohol dehydrogenase
KC397_00085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KC397_00090	COG3978	acetolactate synthase activity
KC397_00100	COG0606	chelatase, subunit chli
KC397_00105	COG0204	Acyl-transferase
KC397_00110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KC397_00115	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KC397_00125	COG3084	Protein conserved in bacteria
KC397_00130	COG4326	sporulation control protein
KC397_00135	COG1272	protein, Hemolysin III
KC397_00145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KC397_00150	COG0569	domain protein
KC397_00155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KC397_00155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KC397_00165	COG0242	peptide deformylase activity
KC397_00170	COG1652	LysM domain
KC397_00175	COG0758	DNA mediated transformation
KC397_00180	COG2922	Belongs to the Smg family
KC397_00185	COG0551	DNA topoisomerase type I activity
KC397_00190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KC397_00195	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KC397_00205	COG0408	coproporphyrinogen oxidase activity
KC397_00210	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KC397_00220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KC397_00260	COG0583	DNA-binding transcription factor activity
KC397_00265	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KC397_00270	COG2960	long-chain fatty acid transporting porin activity
KC397_00275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KC397_00280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KC397_00290	COG0210	DNA helicase
KC397_00330	COG0747	negative chemotaxis
KC397_00335	COG0601	transmembrane transport
KC397_00340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KC397_00350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KC397_00355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KC397_00370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KC397_00375	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KC397_00410	COG0210	DNA helicase
KC397_00415	COG0405	Gamma-glutamyltransferase
KC397_00420	COG1280	lysine exporter protein (LysE YggA)
KC397_00430	COG2962	Rard protein
KC397_00435	COG0514	ATP-dependent DNA helicase (RecQ)
KC397_00450	COG1132	(ABC) transporter
KC397_00455	COG1120	ATPase activity
KC397_00460	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KC397_00475	COG2862	Uncharacterized protein family, UPF0114
KC397_00480	COG1561	YicC-like family, N-terminal region
KC397_00485	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KC397_00490	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KC397_00495	COG1560	Kdo2-lipid A biosynthetic process
KC397_00500	COG1309	transcriptional regulator
KC397_00515	COG2003	Belongs to the UPF0758 family
KC397_00520	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KC397_00525	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KC397_00535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KC397_00550	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KC397_00555	COG0438	transferase activity, transferring glycosyl groups
KC397_00560	COG0438	transferase activity, transferring glycosyl groups
KC397_00565	COG0463	Glycosyl transferase, family 2
KC397_00570	COG0859	PFAM glycosyl transferase family 9
KC397_00575	COG3642	lipopolysaccharide core region biosynthetic process
KC397_00580	COG0438	transferase activity, transferring glycosyl groups
KC397_00585	COG1519	Transferase
KC397_00590	COG0859	PFAM glycosyl transferase family 9
KC397_00595	COG0859	PFAM glycosyl transferase family 9
KC397_00605	COG1560	Kdo2-lipid A biosynthetic process
KC397_00615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KC397_00620	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KC397_00710	COG0438	transferase activity, transferring glycosyl groups
KC397_00715	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KC397_00720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KC397_00725	COG1051	belongs to the nudix hydrolase family
KC397_00750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KC397_00760	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KC397_00765	COG1573	uracil-dna glycosylase
KC397_00770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KC397_00775	COG3068	Protein conserved in bacteria
KC397_00780	COG0668	transmembrane transport
KC397_00785	COG1253	flavin adenine dinucleotide binding
KC397_00790	COG0776	regulation of translation
KC397_00800	COG0151	Belongs to the GarS family
KC397_00805	COG0138	bifunctional purine biosynthesis protein purh
KC397_00815	COG0789	Transcriptional regulator
KC397_00820	COG1940	carbohydrate kinase activity
KC397_00830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KC397_00830	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KC397_00830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KC397_00835	COG2207	Transcriptional regulator
KC397_00850	COG0840	transmembrane signaling receptor activity
KC397_00855	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KC397_00860	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KC397_00865	COG2264	protein methyltransferase activity
KC397_00870	COG0439	Biotin carboxylase
KC397_00875	COG0511	ligase activity, forming carbon-carbon bonds
KC397_00880	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KC397_00885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KC397_00900	COG2814	Major facilitator Superfamily
KC397_00905	COG2205	protein histidine kinase activity
KC397_00905	COG0784	Response regulator, receiver
KC397_00905	COG2198	Histidine kinase
KC397_00905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KC397_00910	COG0248	Ppx GppA phosphatase
KC397_00915	COG0513	Belongs to the DEAD box helicase family
KC397_00920	COG3118	belongs to the thioredoxin family
KC397_00935	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KC397_01010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KC397_01020	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KC397_01030	COG1072	(Pantothenic acid kinase))
KC397_01060	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KC397_01065	COG0250	Participates in transcription elongation, termination and antitermination
KC397_01070	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KC397_01080	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KC397_01085	COG0222	ribosome binding
KC397_01090	COG0085	RNA polymerase activity
KC397_01095	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KC397_01100	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KC397_01105	COG2816	NAD+ diphosphatase activity
KC397_01110	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KC397_01125	COG4942	peptidase
KC397_01130	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KC397_01145	COG0490	domain, Protein
KC397_01145	COG0471	metal ion transport
KC397_01150	COG0688	phosphatidylethanolamine metabolic process
KC397_01155	COG1162	GTPase activity
KC397_01210	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KC397_01215	COG0802	atpase or kinase
KC397_01225	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KC397_01230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KC397_01235	COG1923	regulation of RNA biosynthetic process
KC397_01240	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KC397_01245	COG0330	HflC and HflK could
KC397_01250	COG0330	HflC and HflK could
KC397_01255	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KC397_01260	COG2900	Belongs to the SlyX family
KC397_01270	COG0545	Peptidyl-prolyl cis-trans isomerase
KC397_01275	COG2964	Protein conserved in bacteria
KC397_01280	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KC397_01285	COG2923	Belongs to the DsrF TusC family
KC397_01290	COG2168	tRNA wobble position uridine thiolation
KC397_01300	COG0049	tRNA binding
KC397_01305	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KC397_01315	COG2906	2 iron, 2 sulfur cluster binding
KC397_01325	COG0360	Binds together with S18 to 16S ribosomal RNA
KC397_01330	COG2965	DNA replication, synthesis of RNA primer
KC397_01340	COG0359	binds to the 23S rRNA
KC397_01355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KC397_01365	COG0166	Belongs to the GPI family
KC397_01375	COG0735	belongs to the Fur family
KC397_01380	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KC397_01400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KC397_01410	COG0175	sulfate reduction
KC397_01475	COG1410	methionine synthase
KC397_01475	COG0646	methionine synthase
KC397_01480	COG0527	aspartate kinase activity
KC397_01485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KC397_01495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KC397_01510	COG0629	single-stranded DNA binding
KC397_01515	COG2200	EAL domain
KC397_01515	COG2199	diguanylate cyclase activity
KC397_01540	COG3267	Type II secretory pathway component ExeA
KC397_01540	COG3409	Peptidoglycan-binding domain 1 protein
KC397_01550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KC397_01555	COG1459	type II secretion system
KC397_01565	COG2165	general secretion pathway protein
KC397_01570	COG2165	general secretion pathway protein
KC397_01600	COG1077	Cell shape determining protein MreB Mrl
KC397_01605	COG1792	Involved in formation and maintenance of cell shape
KC397_01610	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KC397_01615	COG0424	maF-like protein
KC397_01620	COG1530	ribonuclease E activity
KC397_01625	COG3164	Protein of unknown function
KC397_01630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KC397_01635	COG0312	modulator of DNA gyrase
KC397_01655	COG0589	response to stress
KC397_01670	COG1438	arginine binding
KC397_01675	COG0039	L-malate dehydrogenase activity
KC397_01680	COG0531	amino acid
KC397_01685	COG0142	geranyltranstransferase activity
KC397_01690	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KC397_01700	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KC397_01705	COG2966	Psort location CytoplasmicMembrane, score
KC397_01710	COG3610	response to peptide
KC397_01725	COG2967	ApaG domain
KC397_01730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KC397_01735	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KC397_01740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KC397_01745	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KC397_01750	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KC397_01780	COG0840	transmembrane signaling receptor activity
KC397_01805	COG0741	lytic transglycosylase activity
KC397_01810	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KC397_01815	COG1194	a g-specific adenine glycosylase
KC397_01825	COG2066	Belongs to the glutaminase family
KC397_01830	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KC397_01835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KC397_01840	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KC397_01850	COG1872	DUF167
KC397_01855	COG0762	integral membrane protein
KC397_01860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KC397_01865	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KC397_01880	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KC397_01885	COG1678	Uncharacterized ACR, COG1678
KC397_01890	COG0189	ligase activity
KC397_01895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KC397_01900	COG2356	endonuclease I
KC397_01915	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KC397_01920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KC397_01925	COG0583	DNA-binding transcription factor activity
KC397_01930	COG4771	TonB-dependent receptor
KC397_01935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KC397_01940	COG0126	phosphoglycerate kinase activity
KC397_01945	COG0191	fructose-bisphosphate aldolase activity
KC397_01950	COG0668	transmembrane transport
KC397_01975	COG3706	GGDEF domain
KC397_01985	COG1349	DNA-binding transcription factor activity
KC397_01990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KC397_02060	COG1674	ftsk spoiiie
KC397_02060	COG1196	nuclear chromosome segregation
KC397_02065	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KC397_02080	COG2239	Acts as a magnesium transporter
KC397_02100	COG2378	regulation of single-species biofilm formation
KC397_02205	COG0210	DNA helicase
KC397_02225	COG3550	peptidyl-serine autophosphorylation
KC397_02260	COG1610	YqeY-like protein
KC397_02265	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KC397_02270	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KC397_02275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KC397_02280	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KC397_02285	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KC397_02290	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KC397_02295	COG1968	undecaprenyl-diphosphatase activity
KC397_02300	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KC397_02305	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KC397_02315	COG0585	pseudouridine synthase activity
KC397_02320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KC397_02330	COG1388	LysM domain
KC397_02330	COG4942	peptidase
KC397_02335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KC397_02340	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KC397_02345	COG1546	Belongs to the CinA family
KC397_02350	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KC397_02360	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KC397_02365	COG0527	aspartate kinase activity
KC397_02415	COG3630	sodium ion export across plasma membrane
KC397_02420	COG5016	pyruvate
KC397_02420	COG0511	ligase activity, forming carbon-carbon bonds
KC397_02425	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KC397_02435	COG1238	metal cluster binding
KC397_02440	COG0612	Peptidase, M16
KC397_02455	COG1854	S-ribosylhomocysteine lyase activity
KC397_02460	COG4536	flavin adenine dinucleotide binding
KC397_02465	COG4137	Cytochrome C assembly protein
KC397_02470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KC397_02480	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KC397_02485	COG0336	Belongs to the RNA methyltransferase TrmD family
KC397_02490	COG0335	large ribosomal subunit rRNA binding
KC397_02495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KC397_02500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KC397_02505	COG3105	Protein conserved in bacteria
KC397_02510	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KC397_02515	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KC397_02520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KC397_02525	COG0723	plastoquinol--plastocyanin reductase activity
KC397_02530	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KC397_02535	COG2857	Cytochrome c1
KC397_02540	COG0625	glutathione transferase activity
KC397_02545	COG2969	positive regulation of protein catabolic process
KC397_02550	COG2823	Periplasmic or secreted lipoprotein
KC397_02555	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KC397_02560	COG0792	nuclease activity
KC397_02565	COG3107	peptidoglycan biosynthetic process
KC397_02570	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KC397_02585	COG3116	cell division
KC397_02590	COG0768	penicillin binding
KC397_02595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KC397_02600	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KC397_02610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KC397_02615	COG0772	Belongs to the SEDS family
KC397_02620	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KC397_02625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KC397_02630	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KC397_02635	COG0849	cell division
KC397_02640	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KC397_02645	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KC397_02655	COG0653	protein targeting
KC397_02660	COG0494	nUDIX hydrolase
KC397_02665	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KC397_02670	COG0505	Belongs to the CarA family
KC397_02675	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KC397_02680	COG0730	response to heat
KC397_02685	COG0583	DNA-binding transcription factor activity
KC397_02705	COG2860	membrane
KC397_02710	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KC397_02720	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KC397_02730	COG0493	'glutamate synthase
KC397_02735	COG0067	glutamate synthase
KC397_02735	COG0070	glutamate synthase
KC397_02735	COG0069	glutamate synthase activity
KC397_02745	COG0067	glutamate synthase
KC397_02745	COG0069	glutamate synthase activity
KC397_02745	COG0070	glutamate synthase
KC397_02750	COG1242	4 iron, 4 sulfur cluster binding
KC397_02755	COG3706	GGDEF domain
KC397_02755	COG2203	Gaf domain
KC397_02755	COG5001	Diguanylate cyclase
KC397_02755	COG4251	negative regulation of phosphorylation
KC397_02760	COG0784	Response regulator, receiver
KC397_02760	COG5002	protein histidine kinase activity
KC397_02760	COG2198	Histidine kinase
KC397_02770	COG0745	RESPONSE REGULATOR receiver
KC397_02780	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KC397_02795	COG0083	homoserine kinase activity
KC397_02800	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KC397_02805	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
KC397_02820	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KC397_02835	COG1115	amino acid carrier protein
KC397_02840	COG3022	response to hydroperoxide
KC397_02850	COG0084	hydrolase, TatD family'
KC397_02855	COG1079	Belongs to the binding-protein-dependent transport system permease family
KC397_02860	COG4603	Belongs to the binding-protein-dependent transport system permease family
KC397_02865	COG3845	ABC transporter
KC397_02870	COG1744	ABC transporter substrate-binding protein PnrA-like
KC397_02875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KC397_02880	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KC397_02885	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KC397_02890	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KC397_02895	COG0813	purine-nucleoside phosphorylase activity
KC397_02905	COG0560	Phosphoserine phosphatase
KC397_02915	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KC397_02920	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KC397_02925	COG0583	DNA-binding transcription factor activity
KC397_02935	COG0583	DNA-binding transcription factor activity
KC397_02975	COG4964	Belongs to the GSP D family
KC397_03025	COG0784	Response regulator, receiver
KC397_03025	COG3437	response regulator, receiver
KC397_03030	COG2059	Chromate
KC397_03040	COG2017	converts alpha-aldose to the beta-anomer
KC397_03045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KC397_03060	COG0569	domain protein
KC397_03060	COG0189	ligase activity
KC397_03075	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KC397_03080	COG2171	N-acyltransferase activity
KC397_03085	COG3141	response to X-ray
KC397_03090	COG0583	DNA-binding transcription factor activity
KC397_03100	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KC397_03105	COG1074	ATP-dependent DNA helicase activity
KC397_03110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KC397_03120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KC397_03120	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KC397_03130	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KC397_03135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KC397_03140	COG2166	iron-sulfur cluster assembly
KC397_03150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KC397_03155	COG0693	protein deglycase activity
KC397_03160	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KC397_03165	COG3248	Nucleoside-binding outer membrane protein
KC397_03175	COG1595	DNA-templated transcription, initiation
KC397_03185	COG0477	Major facilitator Superfamily
KC397_03190	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KC397_03195	COG0826	peptidase U32
KC397_03205	COG0745	RESPONSE REGULATOR receiver
KC397_03210	COG5002	protein histidine kinase activity
KC397_03220	COG0248	Ppx GppA phosphatase
KC397_03225	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KC397_03230	COG0573	inorganic phosphate transmembrane transporter activity
KC397_03235	COG0581	inorganic phosphate transmembrane transporter activity
KC397_03240	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KC397_03245	COG0704	Plays a role in the regulation of phosphate uptake
KC397_03260	COG0450	alkyl hydroperoxide reductase
KC397_03265	COG0583	DNA-binding transcription factor activity
KC397_03270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KC397_03280	COG0517	IMP dehydrogenase activity
KC397_03285	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KC397_03295	COG1862	Preprotein translocase
KC397_03300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KC397_03305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KC397_03310	COG1335	isochorismatase
KC397_03320	COG0483	inositol monophosphate 1-phosphatase activity
KC397_03325	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KC397_03330	COG1959	2 iron, 2 sulfur cluster binding
KC397_03335	COG1104	cysteine desulfurase activity
KC397_03340	COG0822	iron-sulfur transferase activity
KC397_03355	COG0443	Heat shock 70 kDa protein
KC397_03360	COG0633	Ferredoxin
KC397_03365	COG2975	iron-sulfur cluster assembly
KC397_03370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KC397_03375	COG0105	UTP biosynthetic process
KC397_03390	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KC397_03395	COG0124	histidyl-tRNA synthetase
KC397_03400	COG2976	Protein conserved in bacteria
KC397_03405	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KC397_03410	COG1160	GTP binding
KC397_03425	COG1570	exodeoxyribonuclease VII activity
KC397_03430	COG0517	IMP dehydrogenase activity
KC397_03430	COG0516	GMP reductase activity
KC397_03435	COG0519	Catalyzes the synthesis of GMP from XMP
KC397_03435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KC397_03445	COG1584	GPR1 FUN34 yaaH family protein
KC397_03460	COG1473	amidohydrolase
KC397_03470	COG1115	amino acid carrier protein
KC397_03480	COG0583	DNA-binding transcription factor activity
KC397_03510	COG0582	viral genome integration into host DNA
KC397_03520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KC397_03525	COG2867	negative regulation of translational initiation
KC397_03530	COG2914	Belongs to the UPF0125 (RnfH) family
KC397_03535	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KC397_03540	COG0497	DNA recombination
KC397_03545	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KC397_03550	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KC397_03560	COG0443	Heat shock 70 kDa protein
KC397_03565	COG0484	heat shock protein binding
KC397_03595	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KC397_03605	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KC397_03610	COG0583	DNA-binding transcription factor activity
KC397_03615	COG0590	tRNA wobble adenosine to inosine editing
KC397_03620	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KC397_03645	COG0442	prolyl-tRNA aminoacylation
KC397_03650	COG1720	tRNA m6t6A37 methyltransferase activity
KC397_03655	COG0254	rRNA binding
KC397_03660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KC397_03665	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KC397_03670	COG1671	Belongs to the UPF0178 family
KC397_03695	COG3098	single-species biofilm formation
KC397_03700	COG0564	pseudouridine synthase activity
KC397_03705	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KC397_03710	COG0142	geranyltranstransferase activity
KC397_03715	COG1722	exodeoxyribonuclease VII activity
KC397_03720	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KC397_03730	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KC397_03730	COG0301	tRNA thio-modification
KC397_03735	COG0583	DNA-binding transcription factor activity
KC397_03745	COG2363	Small membrane protein
KC397_03755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KC397_03760	COG1611	Belongs to the LOG family
KC397_03775	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KC397_03775	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KC397_03785	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KC397_03790	COG1464	Belongs to the NlpA lipoprotein family
KC397_03795	COG2011	ABC-type metal ion transport system permease component
KC397_03800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KC397_03805	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KC397_03825	COG1263	PTS System
KC397_03825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KC397_03830	COG0366	Alpha amylase catalytic
KC397_03835	COG2271	Major facilitator Superfamily
KC397_03840	COG3851	Histidine kinase
KC397_03845	COG2197	response regulator
KC397_03870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KC397_03875	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KC397_03885	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KC397_03895	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KC397_03900	COG0321	lipoyl(octanoyl) transferase activity
KC397_03905	COG2921	Belongs to the UPF0250 family
KC397_03910	COG1686	Belongs to the peptidase S11 family
KC397_03915	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KC397_03920	COG0772	Belongs to the SEDS family
KC397_03925	COG0768	penicillin binding
KC397_03930	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KC397_03935	COG0799	negative regulation of ribosome biogenesis
KC397_03940	COG1466	dna polymerase III delta subunit
KC397_03945	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
KC397_03955	COG2888	peptidyl-tyrosine sulfation
KC397_03960	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KC397_03965	COG4535	Mg2 and Co2 transporter CorC
KC397_03970	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KC397_03975	COG1702	phosphate starvation-inducible protein PhoH
KC397_03980	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KC397_03985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KC397_03990	COG2190	(PTS) system
KC397_04000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KC397_04005	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KC397_04010	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
KC397_04015	COG3115	cell septum assembly
KC397_04020	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KC397_04035	COG0789	Transcriptional regulator
KC397_04045	COG0330	HflC and HflK could
KC397_04050	COG3118	belongs to the thioredoxin family
KC397_04055	COG0300	oxidoreductase activity
KC397_04060	COG1090	epimerase
KC397_04085	COG0622	Phosphoesterase
KC397_04100	COG3710	Transcriptional regulator
KC397_04105	COG0326	Molecular chaperone. Has ATPase activity
KC397_04115	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KC397_04120	COG3104	oligopeptide transport
KC397_04130	COG0367	asparagine synthase
KC397_04135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KC397_04135	COG4651	solute:proton antiporter activity
KC397_04140	COG1846	Transcriptional regulator
KC397_04140	COG1940	carbohydrate kinase activity
KC397_04145	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KC397_04150	COG2190	(PTS) system
KC397_04150	COG1263	PTS System
KC397_04150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KC397_04165	COG0101	tRNA pseudouridine synthase activity
KC397_04170	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KC397_04175	COG0285	dihydrofolate synthase activity
KC397_04180	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KC397_04185	COG1286	toxin biosynthetic process
KC397_04190	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KC397_04195	COG2056	Na+-H+ antiporter family
KC397_04200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KC397_04215	COG0346	lactoylglutathione lyase activity
KC397_04220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KC397_04225	COG4660	Part of a membrane complex involved in electron transport
KC397_04230	COG4659	FMN binding
KC397_04235	COG4658	electron transport chain
KC397_04240	COG4656	Part of a membrane complex involved in electron transport
KC397_04245	COG2878	Part of a membrane complex involved in electron transport
KC397_04250	COG4657	Part of a membrane complex involved in electron transport
KC397_04260	COG0556	nucleotide-excision repair
KC397_04265	COG2204	response regulator
KC397_04270	COG2198	Histidine kinase
KC397_04275	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KC397_04280	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KC397_04285	COG0521	Mo-molybdopterin cofactor biosynthetic process
KC397_04290	COG0315	cyclic pyranopterin monophosphate synthase activity
KC397_04295	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KC397_04300	COG0314	molybdopterin synthase activity
KC397_04305	COG3706	GGDEF domain
KC397_04310	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KC397_04310	COG0517	IMP dehydrogenase activity
KC397_04310	COG0617	tRNA 3'-terminal CCA addition
KC397_04320	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
KC397_04330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KC397_04330	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KC397_04335	COG0489	protein tyrosine kinase activity
KC397_04340	COG0572	uridine kinase
KC397_04345	COG2982	Protein involved in outer membrane biogenesis
KC397_04350	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
KC397_04365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KC397_04375	COG2067	long-chain fatty acid transport protein
KC397_04390	COG0183	Belongs to the thiolase family
KC397_04395	COG1250	3-hydroxyacyl-CoA dehydrogenase
KC397_04395	COG1024	Enoyl-CoA hydratase
KC397_04400	COG0778	Nitroreductase
KC397_04405	COG0583	DNA-binding transcription factor activity
KC397_04410	COG0745	RESPONSE REGULATOR receiver
KC397_04415	COG2832	Protein of unknown function (DUF454)
KC397_04420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KC397_04430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KC397_04435	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KC397_04440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KC397_04450	COG2983	Belongs to the UPF0260 family
KC397_04470	COG2226	methyltransferase
KC397_04480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KC397_04485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KC397_04495	COG3139	Protein of unknown function (DUF1315)
KC397_04500	COG0252	asparaginase activity
KC397_04505	COG0616	signal peptide processing
KC397_04510	COG1902	pentaerythritol trinitrate reductase activity
KC397_04510	COG0446	pyridine nucleotide-disulphide oxidoreductase
KC397_04515	COG0788	formyltetrahydrofolate deformylase activity
KC397_04525	COG1199	ATP-dependent helicase activity
KC397_04530	COG1214	PFAM Peptidase M22, glycoprotease
KC397_04550	COG0318	PFAM AMP-dependent synthetase and ligase
KC397_04555	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KC397_04565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KC397_04570	COG2894	cell division
KC397_04580	COG3100	YcgL domain-containing protein
KC397_04585	COG2951	lytic endotransglycosylase activity
KC397_04595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KC397_04600	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KC397_04610	COG3842	ATPase activity
KC397_04620	COG1840	ABC-type Fe3 transport system, periplasmic component
KC397_04625	COG2271	Major facilitator Superfamily
KC397_04630	COG3851	Histidine kinase
KC397_04635	COG2197	response regulator
KC397_04670	COG4589	Belongs to the CDS family
KC397_04680	COG1716	ATPase activity
KC397_04680	COG5001	Diguanylate cyclase
KC397_04690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KC397_04690	COG3153	acetyltransferase
KC397_04700	COG1760	l-serine dehydratase
KC397_04705	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KC397_04725	COG1404	Belongs to the peptidase S8 family
KC397_04730	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KC397_04735	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KC397_04740	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KC397_04745	COG2204	response regulator
KC397_04750	COG4191	Histidine kinase
KC397_04755	COG0544	peptidyl-prolyl cis-trans isomerase activity
KC397_04765	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KC397_04770	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KC397_04775	COG0776	regulation of translation
KC397_04780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KC397_04785	COG1555	photosystem II stabilization
KC397_04790	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KC397_04795	COG0539	negative regulation of cytoplasmic translation
KC397_04800	COG0776	regulation of translation
KC397_04805	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
KC397_04810	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KC397_04815	COG0284	orotidine-5'-phosphate decarboxylase activity
KC397_04830	COG0583	DNA-binding transcription factor activity
KC397_04840	COG0686	Belongs to the AlaDH PNT family
KC397_04845	COG1522	sequence-specific DNA binding
KC397_04850	COG1674	ftsk spoiiie
KC397_04855	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KC397_04860	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KC397_04865	COG2186	Transcriptional regulator
KC397_04885	COG0537	adenosine 5'-monophosphoramidase activity
KC397_04910	COG3150	esterase
KC397_04915	COG1252	NADH dehydrogenase
KC397_04930	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KC397_04940	COG4591	ABC-type transport system involved in lipoprotein release permease component
KC397_04945	COG1136	(ABC) transporter
KC397_04950	COG4591	ABC-type transport system involved in lipoprotein release permease component
KC397_04960	COG0658	competence protein
KC397_04960	COG2333	competence protein COMEC
KC397_04965	COG1132	(ABC) transporter
KC397_04980	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KC397_04985	COG2719	SpoVR family
KC397_04990	COG2718	Belongs to the UPF0229 family
KC397_04995	COG2766	serine protein kinase
KC397_05005	COG3013	Belongs to the UPF0304 family
KC397_05015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KC397_05030	COG1882	Formate acetyltransferase
KC397_05055	COG4160	amino acid transport
KC397_05060	COG0708	Exodeoxyribonuclease III
KC397_05065	COG0840	transmembrane signaling receptor activity
KC397_05075	COG3923	Primosomal replication protein n
KC397_05080	COG1199	ATP-dependent helicase activity
KC397_05085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KC397_05090	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KC397_05095	COG3012	SEC-C Motif Domain Protein
KC397_05100	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KC397_05105	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KC397_05110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KC397_05115	COG0215	cysteine-tRNA ligase activity
KC397_05120	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KC397_05125	COG0632	four-way junction helicase activity
KC397_05130	COG2255	four-way junction helicase activity
KC397_05135	COG1271	oxidase subunit
KC397_05140	COG1294	oxidase, subunit
KC397_05145	COG4890	Cyd operon protein YbgT
KC397_05155	COG0824	Thioesterase
KC397_05160	COG0811	peptide transport
KC397_05175	COG0823	Involved in the tonB-independent uptake of proteins
KC397_05180	COG2885	chlorophyll binding
KC397_05185	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KC397_05190	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KC397_05200	COG2205	protein histidine kinase activity
KC397_05200	COG0784	Response regulator, receiver
KC397_05215	COG1012	belongs to the aldehyde dehydrogenase family
KC397_05235	COG1960	acyl-CoA dehydrogenase activity
KC397_05240	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KC397_05250	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KC397_05255	COG1979	alcohol dehydrogenase
KC397_05260	COG1737	Transcriptional regulator
KC397_05265	COG0076	glutamate decarboxylase activity
KC397_05275	COG2431	L-lysine efflux transmembrane transporter activity
KC397_05285	COG3070	regulator of competence-specific genes
KC397_05300	COG3852	Histidine kinase
KC397_05310	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KC397_05315	COG1032	radical SAM domain protein
KC397_05320	COG0488	(ABC) transporter
KC397_05340	COG0745	RESPONSE REGULATOR receiver
KC397_05345	COG5002	protein histidine kinase activity
KC397_05350	COG0346	lactoylglutathione lyase activity
KC397_05355	COG1794	racemase activity, acting on amino acids and derivatives
KC397_05370	COG0840	transmembrane signaling receptor activity
KC397_05375	COG2200	EAL domain
KC397_05375	COG2771	luxR family
KC397_05385	COG0625	glutathione transferase activity
KC397_05405	COG0612	Peptidase, M16
KC397_05420	COG0583	DNA-binding transcription factor activity
KC397_05425	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KC397_05435	COG2350	Protein conserved in bacteria
KC397_05455	COG1301	dicarboxylic acid transport
KC397_05460	COG0159	tryptophan synthase activity
KC397_05465	COG0133	tryptophan synthase activity
KC397_05470	COG0134	indole-3-glycerol-phosphate synthase activity
KC397_05470	COG0135	phosphoribosylanthranilate isomerase activity
KC397_05475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KC397_05480	COG0512	Glutamine amidotransferase of anthranilate synthase
KC397_05485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KC397_05495	COG0613	PHP domain protein
KC397_05500	COG0009	L-threonylcarbamoyladenylate synthase
KC397_05505	COG1187	pseudouridine synthase activity
KC397_05530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KC397_05535	COG4988	ABC transporter
KC397_05540	COG0492	ferredoxin-NADP+ reductase activity
KC397_05560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KC397_05565	COG1454	alcohol dehydrogenase
KC397_05575	COG1414	Transcriptional regulator
KC397_05580	COG1414	Transcriptional regulator
KC397_05590	COG2949	membrane
KC397_05615	COG0640	Transcriptional regulator
KC397_05630	COG0583	DNA-binding transcription factor activity
KC397_05655	COG0281	malic enzyme
KC397_05660	COG1643	Atp-dependent helicase
KC397_05670	COG1757	Na H antiporter
KC397_05675	COG0174	glutamine synthetase
KC397_05680	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KC397_05685	COG1917	Cupin 2, conserved barrel domain protein
KC397_05685	COG1396	sequence-specific DNA binding
KC397_05690	COG1012	belongs to the aldehyde dehydrogenase family
KC397_05695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KC397_05705	COG2957	Belongs to the agmatine deiminase family
KC397_05710	COG1012	belongs to the aldehyde dehydrogenase family
KC397_05715	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KC397_05720	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KC397_05740	COG2885	chlorophyll binding
KC397_05755	COG0247	lactate metabolic process
KC397_05755	COG0277	FAD linked oxidase domain protein
KC397_05775	COG2986	histidine ammonia-lyase
KC397_05785	COG0010	Belongs to the arginase family
KC397_05790	COG1228	amidohydrolase
KC397_05805	COG3099	Belongs to the UPF0263 family
KC397_05810	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KC397_05820	COG5001	Diguanylate cyclase
KC397_05825	COG0417	DNA replication proofreading
KC397_05830	COG2197	response regulator
KC397_05835	COG0322	excinuclease ABC activity
KC397_05865	COG2133	pyrroloquinoline quinone binding
KC397_05885	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KC397_05890	COG0072	phenylalanine-tRNA ligase activity
KC397_05890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KC397_05895	COG0776	regulation of translation
KC397_05905	COG0500	methyltransferase
KC397_05935	COG5001	Diguanylate cyclase
KC397_05940	COG0295	cytidine deaminase activity
KC397_05945	COG1346	cytolysis
KC397_05950	COG1380	Effector of murein hydrolase LrgA
KC397_05955	COG2925	Exonuclease
KC397_05965	COG1823	symporter activity
KC397_05970	COG0702	epimerase
KC397_05975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KC397_05980	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KC397_05985	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KC397_06000	COG2988	succinylglutamate desuccinylase activity
KC397_06005	COG4139	cobalamin transport
KC397_06010	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KC397_06060	COG0583	DNA-binding transcription factor activity
KC397_06070	COG1451	nucleotide metabolic process
KC397_06085	COG3063	Type IV pilus biogenesis stability protein PilW
KC397_06090	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KC397_06110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KC397_06125	COG3290	protein histidine kinase activity
KC397_06130	COG4565	transcriptional regulatory protein
KC397_06140	COG0835	chemotaxis
KC397_06140	COG0784	Response regulator, receiver
KC397_06200	COG1278	Cold shock
KC397_06235	COG0668	transmembrane transport
KC397_06250	COG0745	RESPONSE REGULATOR receiver
KC397_06255	COG5002	protein histidine kinase activity
KC397_06280	COG2010	Cytochrome c
KC397_06300	COG3391	amine dehydrogenase activity
KC397_06305	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KC397_06310	COG1254	Belongs to the acylphosphatase family
KC397_06315	COG2920	part of a sulfur-relay system
KC397_06320	COG0670	Belongs to the BI1 family
KC397_06325	COG1126	abc transporter atp-binding protein
KC397_06330	COG0765	amino acid transport
KC397_06335	COG4597	amino acid ABC transporter
KC397_06340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KC397_06350	COG0561	phosphatase activity
KC397_06355	COG0602	queuosine metabolic process
KC397_06365	COG3005	denitrification pathway
KC397_06370	COG0243	molybdopterin cofactor binding
KC397_06400	COG2999	glutathione oxidoreductase activity
KC397_06415	COG3706	GGDEF domain
KC397_06425	COG3706	GGDEF domain
KC397_06430	COG0443	Heat shock 70 kDa protein
KC397_06445	COG3706	GGDEF domain
KC397_06470	COG3005	denitrification pathway
KC397_06480	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KC397_06485	COG1643	Atp-dependent helicase
KC397_06585	COG3501	Rhs element vgr protein
KC397_06610	COG1115	amino acid carrier protein
KC397_06630	COG1666	GTP binding
KC397_06635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KC397_06640	COG0574	Belongs to the PEP-utilizing enzyme family
KC397_06640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KC397_06655	COG2996	Protein conserved in bacteria
KC397_06665	COG3008	intermembrane lipid transfer
KC397_06670	COG2995	paraquat-inducible protein a
KC397_06675	COG1132	(ABC) transporter
KC397_06680	COG1956	GAF domain-containing protein
KC397_06685	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KC397_06705	COG0308	aminopeptidase N
KC397_06720	COG0167	dihydroorotate dehydrogenase activity
KC397_06730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KC397_06730	COG0116	Belongs to the methyltransferase superfamily
KC397_06740	COG0488	(ABC) transporter
KC397_06755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KC397_06760	COG1067	ATP-dependent peptidase activity
KC397_06765	COG3120	sequence-specific DNA binding
KC397_06860	COG2205	protein histidine kinase activity
KC397_06860	COG0784	Response regulator, receiver
KC397_06875	COG3278	Belongs to the heme-copper respiratory oxidase family
KC397_06890	COG2010	Cytochrome c
KC397_06900	COG2217	Heavy metal translocating P-type atpase
KC397_06915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KC397_06920	COG0589	response to stress
KC397_06945	COG3842	ATPase activity
KC397_06955	COG1177	transmembrane transport
KC397_06965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KC397_06970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KC397_06975	COG0004	ammonium transporteR
KC397_06990	COG0437	4 iron, 4 sulfur cluster binding
KC397_06995	COG3383	formate dehydrogenase (NAD+) activity
KC397_06995	COG0243	molybdopterin cofactor binding
KC397_07005	COG3381	protein complex oligomerization
KC397_07025	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KC397_07040	COG3852	Histidine kinase
KC397_07045	COG2204	response regulator
KC397_07055	COG4662	Binding-protein-dependent transport system inner membrane component
KC397_07060	COG3842	ATPase activity
KC397_07065	COG0746	molybdenum cofactor guanylyltransferase activity
KC397_07070	COG0303	'Molybdopterin
KC397_07080	COG1940	carbohydrate kinase activity
KC397_07085	COG3148	PFAM DTW domain containing protein
KC397_07095	COG0840	transmembrane signaling receptor activity
KC397_07100	COG0791	NLP P60 protein
KC397_07110	COG3001	Fructosamine kinase
KC397_07120	COG0307	riboflavin synthase, alpha
KC397_07135	COG1793	dna ligase
KC397_07140	COG4667	esterase of the alpha-beta hydrolase superfamily
KC397_07160	COG0848	biopolymer transport protein
KC397_07165	COG0811	peptide transport
KC397_07170	COG0811	peptide transport
KC397_07180	COG3040	lipid binding
KC397_07185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KC397_07190	COG0039	L-malate dehydrogenase activity
KC397_07195	COG1653	transport
KC397_07205	COG0395	ABC-type sugar transport system, permease component
KC397_07210	COG3842	ATPase activity
KC397_07215	COG1349	DNA-binding transcription factor activity
KC397_07220	COG0584	glycerophosphoryl diester phosphodiesterase
KC397_07225	COG2731	YhcH YjgK YiaL family protein
KC397_07245	COG0625	glutathione transferase activity
KC397_07255	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KC397_07265	COG2200	EAL domain
KC397_07270	COG2195	Cleaves the N-terminal amino acid of tripeptides
KC397_07285	COG2814	Major facilitator Superfamily
KC397_07290	COG1566	PFAM secretion protein HlyD family protein
KC397_07305	COG2828	Protein conserved in bacteria
KC397_07310	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KC397_07315	COG0372	Belongs to the citrate synthase family
KC397_07320	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KC397_07330	COG2169	Transcriptional regulator
KC397_07330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KC397_07370	COG1129	ABC transporter
KC397_07380	COG3250	beta-galactosidase activity
KC397_07390	COG2991	Protein conserved in bacteria
KC397_07395	COG0778	Nitroreductase
KC397_07400	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KC397_07405	COG0583	DNA-binding transcription factor activity
KC397_07415	COG4191	Histidine kinase
KC397_07415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KC397_07420	COG0471	metal ion transport
KC397_07440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KC397_07450	COG3768	UPF0283 membrane protein
KC397_07455	COG3106	COG3106 Predicted ATPase
KC397_07470	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KC397_07475	COG2205	protein histidine kinase activity
KC397_07475	COG0784	Response regulator, receiver
KC397_07485	COG0494	nUDIX hydrolase
KC397_07490	COG0814	amino acid
KC397_07495	COG1760	l-serine dehydratase
KC397_07500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KC397_07505	COG1136	(ABC) transporter
KC397_07505	COG0577	efflux transmembrane transporter activity
KC397_07515	COG0720	synthase
KC397_07520	COG0840	transmembrane signaling receptor activity
KC397_07525	COG0017	Asparaginyl-tRNA synthetase
KC397_07540	COG1448	Aminotransferase
KC397_07550	COG0517	IMP dehydrogenase activity
KC397_07555	COG2176	DNA-directed DNA polymerase activity
KC397_07560	COG0840	transmembrane signaling receptor activity
KC397_07565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KC397_07570	COG1846	Transcriptional regulator
KC397_07575	COG2197	response regulator
KC397_07595	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KC397_07610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KC397_07615	COG3108	Peptidase M15
KC397_07620	COG2989	Protein conserved in bacteria
KC397_07645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KC397_07660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KC397_07665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KC397_07695	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KC397_07700	COG3265	gluconokinase activity
KC397_07715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KC397_07725	COG0840	transmembrane signaling receptor activity
KC397_07760	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KC397_07775	COG4181	ATPase activity
KC397_07780	COG0534	Mate efflux family protein
KC397_07785	COG0702	epimerase
KC397_07795	COG2814	Major facilitator Superfamily
KC397_07805	COG1061	Type III restriction enzyme res subunit
KC397_07820	COG2205	protein histidine kinase activity
KC397_07825	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KC397_07830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KC397_07840	COG1278	Cold shock
KC397_07850	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KC397_07870	COG0814	amino acid
KC397_07880	COG1131	(ABC) transporter
KC397_07885	COG0842	Transport permease protein
KC397_07895	COG3313	Fe-S protein
KC397_07905	COG4134	Bacterial extracellular solute-binding protein
KC397_07910	COG4135	transport system, permease component
KC397_07915	COG4136	ATPase activity
KC397_07920	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KC397_07925	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KC397_07935	COG0564	pseudouridine synthase activity
KC397_07945	COG0733	neurotransmitter:sodium symporter activity
KC397_07955	COG0626	cystathionine gamma-synthase activity
KC397_07985	COG0519	Catalyzes the synthesis of GMP from XMP
KC397_08000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KC397_08015	COG1842	Phage shock protein A
KC397_08020	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KC397_08030	COG4168	peptide transport system, permease
KC397_08035	COG4171	peptide transport system, permease
KC397_08045	COG4172	Belongs to the ABC transporter superfamily
KC397_08060	COG1227	inorganic diphosphatase activity
KC397_08080	COG0243	molybdopterin cofactor binding
KC397_08085	COG3005	denitrification pathway
KC397_08090	COG4459	periplasmic nitrate reductase
KC397_08095	COG0390	transport system, permease component
KC397_08100	COG2116	formate transmembrane transporter activity
KC397_08120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KC397_08125	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KC397_08130	COG1435	thymidine kinase activity
KC397_08145	COG4106	trans-aconitate 2-methyltransferase activity
KC397_08150	COG0500	methyltransferase
KC397_08155	COG0189	ligase activity
KC397_08155	COG4067	protein conserved in archaea
KC397_08165	COG0189	ligase activity
KC397_08175	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KC397_08180	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
KC397_08185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KC397_08190	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KC397_08195	COG0745	RESPONSE REGULATOR receiver
KC397_08200	COG3381	protein complex oligomerization
KC397_08205	COG1609	Transcriptional regulator
KC397_08210	COG3070	regulator of competence-specific genes
KC397_08230	COG0297	glycogen (starch) synthase activity
KC397_08235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KC397_08245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KC397_08265	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KC397_08270	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KC397_08275	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KC397_08280	COG0542	response to heat
KC397_08285	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KC397_08290	COG1278	Cold shock
KC397_08300	COG1187	pseudouridine synthase activity
KC397_08305	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KC397_08305	COG0140	phosphoribosyl-ATP diphosphatase activity
KC397_08315	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KC397_08320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KC397_08325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KC397_08325	COG0131	Imidazoleglycerol-phosphate dehydratase
KC397_08330	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KC397_08335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KC397_08340	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KC397_08350	COG1757	Na H antiporter
KC397_08355	COG2916	Histone family protein nucleoid-structuring protein H-NS
KC397_08360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KC397_08365	COG0482	sulfurtransferase activity
KC397_08370	COG2915	High frequency lysogenization protein hflD homolog
KC397_08375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KC397_08395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KC397_08410	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_08420	COG0501	Belongs to the peptidase M48B family
KC397_08430	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KC397_08445	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KC397_08450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KC397_08460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KC397_08460	COG2146	nitrite reductase [NAD(P)H] activity
KC397_08465	COG1116	anion transmembrane transporter activity
KC397_08470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KC397_08475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KC397_08475	COG1116	anion transmembrane transporter activity
KC397_08490	COG1648	precorrin-2 dehydrogenase activity
KC397_08490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KC397_08495	COG0243	molybdopterin cofactor binding
KC397_08505	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KC397_08510	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KC397_08515	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KC397_08520	COG0653	protein targeting
KC397_08535	COG3706	GGDEF domain
KC397_08545	COG4120	Belongs to the binding-protein-dependent transport system permease family
KC397_08555	COG3092	negative regulation of chromosome organization
KC397_08560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KC397_08565	COG0280	phosphate acetyltransferase
KC397_08565	COG0857	belongs to the CobB CobQ family
KC397_08570	COG3174	membrane
KC397_08575	COG0435	Glutathione S-transferase
KC397_08590	COG0444	Belongs to the ABC transporter superfamily
KC397_08595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KC397_08600	COG0601	transmembrane transport
KC397_08630	COG0204	Acyl-transferase
KC397_08630	COG0318	PFAM AMP-dependent synthetase and ligase
KC397_08635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KC397_08640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KC397_08660	COG1216	Glycosyl transferase, family 2
KC397_08665	COG2986	histidine ammonia-lyase
KC397_08700	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_08715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KC397_08725	COG2199	diguanylate cyclase activity
KC397_08725	COG2200	EAL domain
KC397_08725	COG2202	Pas domain
KC397_08730	COG1621	beta-fructofuranosidase activity
KC397_08740	COG1263	PTS System
KC397_08740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KC397_08750	COG0745	RESPONSE REGULATOR receiver
KC397_08760	COG3708	Transcriptional regulator
KC397_08760	COG2207	Transcriptional regulator
KC397_08765	COG2814	Major facilitator Superfamily
KC397_08770	COG1566	PFAM secretion protein HlyD family protein
KC397_08775	COG1538	Outer membrane efflux protein
KC397_08785	COG0747	negative chemotaxis
KC397_08790	COG0601	transmembrane transport
KC397_08795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KC397_08800	COG4172	Belongs to the ABC transporter superfamily
KC397_08805	COG0351	phosphomethylpyrimidine kinase
KC397_08815	COG0352	thiamine-phosphate diphosphorylase activity
KC397_08820	COG1741	Belongs to the pirin family
KC397_08825	COG2723	6-phospho-beta-galactosidase activity
KC397_08830	COG1609	Transcriptional regulator
KC397_08840	COG1120	ATPase activity
KC397_08845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KC397_08855	COG4774	siderophore transport
KC397_08855	COG1629	transport
KC397_08860	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KC397_08865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KC397_08870	COG4592	Periplasmic binding protein
KC397_08885	COG2226	methyltransferase
KC397_08885	COG3433	isochorismatase activity
KC397_08885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KC397_08890	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KC397_08895	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_08900	COG1169	isochorismate synthase
KC397_08905	COG1021	2,3-dihydroxybenzoate-AMP ligase
KC397_08915	COG2814	Major facilitator Superfamily
KC397_08920	COG2249	NAD(P)H dehydrogenase (quinone) activity
KC397_08960	COG1294	oxidase, subunit
KC397_08965	COG1271	oxidase subunit
KC397_08970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KC397_08985	COG3258	Cytochrome c
KC397_08990	COG2863	cytochrome
KC397_09000	COG3423	Transcriptional regulator
KC397_09005	COG2801	Transposase and inactivated derivatives
KC397_09010	COG2842	Transposition protein
KC397_09120	COG0640	Transcriptional regulator
KC397_09130	COG4373	Mu-like prophage FluMu protein gp28
KC397_09135	COG4383	Mu-like prophage protein gp29
KC397_09150	COG4397	Mu-like prophage major head subunit gpT
KC397_09170	COG4387	Mu-like prophage protein GP36
KC397_09190	COG4386	tail sheath protein
KC397_09200	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
KC397_09230	COG3299	homolog of phage Mu protein gp47
KC397_09235	COG3778	Protein conserved in bacteria
KC397_09270	COG4566	intracellular signal transduction
KC397_09290	COG2194	sulfuric ester hydrolase activity
KC397_09295	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KC397_09300	COG1368	sulfuric ester hydrolase activity
KC397_09305	COG0513	Belongs to the DEAD box helicase family
KC397_09315	COG0671	phosphoesterase, PA-phosphatase related
KC397_09325	COG0642	Histidine kinase
KC397_09340	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KC397_09345	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KC397_09375	COG2207	Transcriptional regulator
KC397_09380	COG1881	PFAM PEBP family protein
KC397_09395	COG1278	Cold shock
KC397_09405	COG0697	spore germination
KC397_09410	COG0431	NADPH-dependent FMN reductase
KC397_09440	COG1073	alpha beta
KC397_09445	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_09455	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_09465	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_09470	COG4221	oxidoreductase activity
KC397_09490	COG1309	transcriptional regulator
KC397_09525	COG1959	2 iron, 2 sulfur cluster binding
KC397_09545	COG5001	Diguanylate cyclase
KC397_09545	COG4251	negative regulation of phosphorylation
KC397_09545	COG3706	GGDEF domain
KC397_09545	COG2203	Gaf domain
KC397_09570	COG3706	GGDEF domain
KC397_09630	COG3621	Patatin-like phospholipase
KC397_09665	COG2203	Gaf domain
KC397_09665	COG2199	diguanylate cyclase activity
KC397_09680	COG3126	Type III secretion system lipoprotein chaperone (YscW)
KC397_09685	COG1946	Acyl-CoA thioesterase
KC397_09690	COG1522	sequence-specific DNA binding
KC397_09735	COG2885	chlorophyll binding
KC397_09765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KC397_09780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KC397_09785	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KC397_09805	COG1580	Controls the rotational direction of flagella during chemotaxis
KC397_09810	COG1191	sigma factor activity
KC397_09815	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KC397_09820	COG1360	Flagellar Motor Protein
KC397_09830	COG3015	lipoprotein NlpE involved in copper resistance
KC397_09835	COG0702	epimerase
KC397_09870	COG4786	Flagellar basal body rod
KC397_09870	COG1256	bacterial-type flagellum assembly
KC397_09880	COG1706	bacterial-type flagellum-dependent cell motility
KC397_09885	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KC397_09890	COG4786	Flagellar basal body rod
KC397_09900	COG1749	Flagellar hook protein flgE
KC397_09905	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
KC397_09910	COG1558	bacterial-type flagellum-dependent cell motility
KC397_09915	COG1815	bacterial-type flagellum-dependent cell motility
KC397_09935	COG1388	LysM domain
KC397_09935	COG0741	lytic transglycosylase activity
KC397_09940	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KC397_09960	COG0477	Major facilitator Superfamily
KC397_09965	COG2855	membrane
KC397_09985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KC397_09990	COG0596	Alpha beta hydrolase
KC397_09995	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KC397_10000	COG1169	isochorismate synthase
KC397_10005	COG0436	Aminotransferase
KC397_10010	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KC397_10015	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KC397_10050	COG0616	signal peptide processing
KC397_10055	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_10070	COG0587	DNA-directed DNA polymerase activity
KC397_10075	COG0784	Response regulator, receiver
KC397_10075	COG0835	chemotaxis
KC397_10080	COG1940	carbohydrate kinase activity
KC397_10085	COG0469	pyruvate kinase activity
KC397_10090	COG4667	esterase of the alpha-beta hydrolase superfamily
KC397_10105	COG0733	neurotransmitter:sodium symporter activity
KC397_10120	COG1263	PTS System
KC397_10120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KC397_10130	COG1263	PTS System
KC397_10130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KC397_10130	COG2190	(PTS) system
KC397_10135	COG0084	hydrolase, TatD family'
KC397_10140	COG0470	DNA polymerase III
KC397_10145	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KC397_10150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KC397_10155	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KC397_10160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KC397_10180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KC397_10185	COG0416	fatty acid biosynthetic process
KC397_10190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KC397_10195	COG1399	metal-binding, possibly nucleic acid-binding protein
KC397_10200	COG0424	maF-like protein
KC397_10205	COG0564	pseudouridine synthase activity
KC397_10210	COG1530	ribonuclease E activity
KC397_10220	COG0659	secondary active sulfate transmembrane transporter activity
KC397_10230	COG1012	belongs to the aldehyde dehydrogenase family
KC397_10230	COG1454	alcohol dehydrogenase
KC397_10235	COG2095	MarC family integral membrane protein
KC397_10240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KC397_10245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KC397_10250	COG1757	Na H antiporter
KC397_10260	COG3081	Nucleoid-associated protein
KC397_10265	COG3082	Protein of unknown function (DUF1414)
KC397_10270	COG3083	sulfuric ester hydrolase activity
KC397_10290	COG1448	Aminotransferase
KC397_10300	COG0123	including yeast histone deacetylase and acetoin utilization protein
KC397_10315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KC397_10355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KC397_10360	COG2159	amidohydrolase
KC397_10365	COG0583	DNA-binding transcription factor activity
KC397_10380	COG0667	Aldo Keto reductase
KC397_10405	COG3384	dioxygenase
KC397_10410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KC397_10415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KC397_10440	COG2853	Lipoprotein
KC397_10455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KC397_10460	COG1138	Cytochrome C-type biogenesis protein
KC397_10465	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KC397_10470	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KC397_10475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KC397_10480	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KC397_10485	COG4133	protoheme IX ABC transporter activity
KC397_10495	COG0835	chemotaxis
KC397_10505	COG1192	Involved in chromosome partitioning
KC397_10510	COG2201	protein-glutamate methylesterase activity
KC397_10515	COG0784	Response regulator, receiver
KC397_10515	COG0643	Histidine kinase
KC397_10515	COG2198	Histidine kinase
KC397_10520	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KC397_10550	COG2062	phosphohistidine phosphatase, SixA
KC397_10560	COG3102	Protein conserved in bacteria
KC397_10565	COG0018	arginyl-trna synthetase
KC397_10590	COG1918	ferrous iron import across plasma membrane
KC397_10600	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KC397_10605	COG1121	(ABC) transporter
KC397_10610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KC397_10625	COG0508	dehydrogenase complex catalyzes the overall conversion of
KC397_10630	COG0567	Dehydrogenase, E1 component
KC397_10645	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KC397_10660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KC397_10670	COG0033	Phosphoglucomutase
KC397_10675	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KC397_10680	COG0596	Alpha beta hydrolase
KC397_10695	COG1346	cytolysis
KC397_10700	COG1380	Effector of murein hydrolase LrgA
KC397_10705	COG0583	DNA-binding transcription factor activity
KC397_10715	COG0735	belongs to the Fur family
KC397_10720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KC397_10725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KC397_10730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KC397_10735	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KC397_10735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KC397_10750	COG3101	peptidyl-lysine hydroxylation
KC397_10755	COG2860	membrane
KC397_10760	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_10765	COG0583	DNA-binding transcription factor activity
KC397_10770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KC397_10775	COG2890	protein-(glutamine-N5) methyltransferase activity
KC397_10780	COG2840	Smr protein MutS2
KC397_10795	COG1987	bacterial-type flagellum assembly
KC397_10845	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KC397_10855	COG1677	Flagellar hook-basal body complex protein FliE
KC397_10875	COG1516	flagellar protein fliS
KC397_10885	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KC397_10890	COG1334	flagellar protein FlaG
KC397_10895	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KC397_10910	COG2837	iron assimilation
KC397_10930	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KC397_10940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KC397_10950	COG1393	Belongs to the ArsC family
KC397_10960	COG1876	peptidase activity
KC397_10970	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KC397_10980	COG2716	regulation of RNA biosynthetic process
KC397_10985	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KC397_11005	COG4783	chaperone-mediated protein folding
KC397_11010	COG1393	Belongs to the ArsC family
KC397_11030	COG2233	PERMEase
KC397_11040	COG0737	Belongs to the 5'-nucleotidase family
KC397_11045	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KC397_11050	COG2912	Transglutaminase-like superfamily
KC397_11060	COG2890	protein-(glutamine-N5) methyltransferase activity
KC397_11065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KC397_11070	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KC397_11075	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KC397_11080	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KC397_11085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KC397_11090	COG0193	aminoacyl-tRNA hydrolase activity
KC397_11190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KC397_11205	COG1705	Flagellar rod assembly protein muramidase FlgJ
KC397_11205	COG3951	Flagellar rod assembly protein muramidase FlgJ
KC397_11210	COG1706	bacterial-type flagellum-dependent cell motility
KC397_11215	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KC397_11225	COG4787	bacterial-type flagellum-dependent cell motility
KC397_11245	COG1815	bacterial-type flagellum-dependent cell motility
KC397_11250	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KC397_11255	COG0784	Response regulator, receiver
KC397_11255	COG0835	chemotaxis
KC397_11265	COG2747	anti-sigma28 factor FlgM
KC397_11295	COG4695	Portal protein
KC397_11385	COG2194	sulfuric ester hydrolase activity
KC397_11390	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KC397_11410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KC397_11415	COG2217	Heavy metal translocating P-type atpase
KC397_11415	COG2608	mercury ion transmembrane transporter activity
KC397_11445	COG2840	Smr protein MutS2
KC397_11450	COG1187	pseudouridine synthase activity
KC397_11455	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KC397_11460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KC397_11465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KC397_11470	COG0121	glutamine amidotransferase
KC397_11475	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KC397_11480	COG1960	acyl-CoA dehydrogenase activity
KC397_11490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KC397_11495	COG0328	RNA-DNA hybrid ribonuclease activity
KC397_11500	COG2226	methyltransferase
KC397_11505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KC397_11510	COG0741	lytic transglycosylase activity
KC397_11510	COG1388	LysM domain
KC397_11520	COG3021	interspecies interaction between organisms
KC397_11525	COG0347	Belongs to the P(II) protein family
KC397_11535	COG0037	tRNA processing
KC397_11540	COG0825	malonyl-CoA metabolic process
KC397_11545	COG0587	DNA-directed DNA polymerase activity
KC397_11550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KC397_11565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KC397_11570	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KC397_11575	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
KC397_11585	COG0750	zinc metalloprotease
KC397_11590	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KC397_11595	COG0575	Belongs to the CDS family
KC397_11600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KC397_11615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KC397_11620	COG0052	Belongs to the universal ribosomal protein uS2 family
KC397_11625	COG0024	Methionine aminopeptidase
KC397_11630	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KC397_11640	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KC397_11645	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KC397_11650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KC397_11655	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KC397_11670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KC397_11670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KC397_11675	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KC397_11680	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KC397_11685	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KC397_11695	COG1073	alpha beta
KC397_11700	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KC397_11705	COG2252	PERMEase
KC397_11710	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KC397_11720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KC397_11730	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KC397_11735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KC397_11740	COG2195	Cleaves the N-terminal amino acid of tripeptides
KC397_11745	COG4067	protein conserved in archaea
KC397_11745	COG0189	ligase activity
KC397_11750	COG0189	ligase activity
KC397_11760	COG0733	neurotransmitter:sodium symporter activity
KC397_11765	COG3706	GGDEF domain
KC397_11765	COG5001	Diguanylate cyclase
KC397_11765	COG2203	Gaf domain
KC397_11765	COG4251	negative regulation of phosphorylation
KC397_11775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KC397_11790	COG1477	protein flavinylation
KC397_11795	COG2871	sodium ion transport
KC397_11800	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KC397_11805	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KC397_11815	COG1805	sodium ion transport
KC397_11820	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KC397_11825	COG0271	Belongs to the BolA IbaG family
KC397_11905	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KC397_11910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KC397_11915	COG0590	tRNA wobble adenosine to inosine editing
KC397_11925	COG0542	response to heat
KC397_11935	COG0564	pseudouridine synthase activity
KC397_11940	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KC397_11945	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KC397_11950	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KC397_11955	COG1605	Chorismate mutase
KC397_11955	COG0077	Prephenate dehydratase
KC397_11960	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KC397_11965	COG5001	Diguanylate cyclase
KC397_11970	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KC397_11975	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
KC397_11985	COG0488	(ABC) transporter
KC397_11995	COG0287	Prephenate dehydrogenase
KC397_11995	COG1605	Chorismate mutase
KC397_12000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KC397_12005	COG3275	phosphorelay sensor kinase activity
KC397_12010	COG3279	Response regulator of the LytR AlgR family
KC397_12020	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KC397_12025	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KC397_12040	COG1966	Carbon starvation protein
KC397_12045	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KC397_12050	COG1047	Peptidyl-prolyl cis-trans
KC397_12055	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KC397_12060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KC397_12065	COG0196	riboflavin kinase activity
KC397_12070	COG0728	peptidoglycan biosynthetic process
KC397_12075	COG0268	Binds directly to 16S ribosomal RNA
KC397_12080	COG0640	Transcriptional regulator
KC397_12085	COG0583	DNA-binding transcription factor activity
KC397_12090	COG1283	sodium-dependent phosphate transmembrane transporter activity
KC397_12105	COG0730	response to heat
KC397_12115	COG0494	nUDIX hydrolase
KC397_12130	COG0667	Aldo Keto reductase
KC397_12140	COG2204	response regulator
KC397_12145	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KC397_12165	COG0513	Belongs to the DEAD box helicase family
KC397_12190	COG3153	acetyltransferase
KC397_12195	COG3154	lipid carrier protein
KC397_12205	COG0826	peptidase U32
KC397_12210	COG0826	peptidase U32
KC397_12215	COG0534	Mate efflux family protein
KC397_12235	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KC397_12240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KC397_12245	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KC397_12255	COG0195	Participates in both transcription termination and antitermination
KC397_12260	COG0779	Required for maturation of 30S ribosomal subunits
KC397_12275	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KC397_12280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KC397_12285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KC397_12290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KC397_12295	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KC397_12300	COG1534	Rna-binding protein
KC397_12305	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KC397_12310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KC397_12315	COG2027	D-alanyl-D-alanine carboxypeptidase
KC397_12320	COG2239	Acts as a magnesium transporter
KC397_12330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KC397_12335	COG0739	heme binding
KC397_12350	COG0316	Belongs to the HesB IscA family
KC397_12355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KC397_12365	COG0628	permease
KC397_12375	COG0784	Response regulator, receiver
KC397_12375	COG2205	protein histidine kinase activity
KC397_12380	COG0747	negative chemotaxis
KC397_12390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KC397_12395	COG0444	Belongs to the ABC transporter superfamily
KC397_12400	COG4608	Belongs to the ABC transporter superfamily
KC397_12410	COG2971	BadF BadG BcrA BcrD
KC397_12425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KC397_12430	COG3842	ATPase activity
KC397_12440	COG1840	ABC-type Fe3 transport system, periplasmic component
KC397_12445	COG0004	ammonium transporteR
KC397_12450	COG0347	Belongs to the P(II) protein family
KC397_12455	COG3112	Uncharacterised protein family (UPF0231)
KC397_12460	COG1049	propionate catabolic process, 2-methylcitrate cycle
KC397_12465	COG1752	Esterase of the alpha-beta hydrolase superfamily
KC397_12470	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KC397_12475	COG1643	Atp-dependent helicase
KC397_12480	COG1489	DNA binding
KC397_12485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KC397_12490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KC397_12500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KC397_12505	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KC397_12510	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KC397_12515	COG0842	Transport permease protein
KC397_12520	COG1131	(ABC) transporter
KC397_12525	COG0288	reversible hydration of carbon dioxide
KC397_12540	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KC397_12545	COG0508	dehydrogenase complex catalyzes the overall conversion of
KC397_12550	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KC397_12555	COG2186	Transcriptional regulator
KC397_12560	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KC397_12565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KC397_12570	COG4974	Belongs to the 'phage' integrase family
KC397_12595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KC397_12600	COG1459	type II secretion system
KC397_12615	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KC397_12625	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KC397_12635	COG3150	esterase
KC397_12645	COG3151	Protein conserved in bacteria
KC397_12650	COG0494	nUDIX hydrolase
KC397_12655	COG1538	Outer membrane efflux protein
KC397_12660	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KC397_12660	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KC397_12665	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KC397_12675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KC397_12680	COG3025	triphosphatase activity
KC397_12685	COG1392	Phosphate transport regulator
KC397_12690	COG0306	phosphate transporter
KC397_12695	COG4991	sh3 domain protein
KC397_12705	COG3409	Peptidoglycan-binding domain 1 protein
KC397_12705	COG3267	Type II secretory pathway component ExeA
KC397_12710	COG0617	tRNA 3'-terminal CCA addition
KC397_12715	COG0148	phosphopyruvate hydratase activity
KC397_12720	COG0504	CTP synthase activity
KC397_12725	COG3956	TIGRFAM MazG family protein
KC397_12730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KC397_12735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KC397_12745	COG0736	holo-[acyl-carrier-protein] synthase activity
KC397_12750	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KC397_12755	COG1381	Involved in DNA repair and RecF pathway recombination
KC397_12760	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KC397_12765	COG0571	ribonuclease III activity
KC397_12775	COG0481	GTPase activity
KC397_12780	COG3086	response to oxidative stress
KC397_12795	COG1595	DNA-templated transcription, initiation
KC397_12800	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KC397_12810	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KC397_12830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KC397_12835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KC397_12840	COG3079	Belongs to the UPF0149 family
KC397_12845	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KC397_12855	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KC397_12865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KC397_12870	COG0440	acetolactate synthase activity
KC397_12875	COG0028	Belongs to the TPP enzyme family
KC397_12880	COG1022	Amp-dependent synthetase and ligase
KC397_12885	COG0583	DNA-binding transcription factor activity
KC397_12910	COG0473	3-isopropylmalate dehydrogenase activity
KC397_12915	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KC397_12920	COG0066	3-isopropylmalate dehydratase activity
KC397_12965	COG3437	response regulator, receiver
KC397_12975	COG2199	diguanylate cyclase activity
KC397_12975	COG2200	EAL domain
KC397_12975	COG2203	Gaf domain
KC397_13050	COG2916	Histone family protein nucleoid-structuring protein H-NS
KC397_13095	COG2999	glutathione oxidoreductase activity
KC397_13100	COG0604	alcohol dehydrogenase
KC397_13240	COG0795	lipopolysaccharide-transporting ATPase activity
KC397_13245	COG0795	lipopolysaccharide-transporting ATPase activity
KC397_13250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KC397_13260	COG0525	valine-tRNA ligase activity
KC397_13265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KC397_13270	COG0564	pseudouridine synthase activity
KC397_13280	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KC397_13285	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KC397_13290	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KC397_13295	COG0540	Belongs to the ATCase OTCase family
KC397_13305	COG0251	oxidation-reduction process
KC397_13310	COG0204	Acyl-transferase
KC397_13315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KC397_13320	COG5007	Belongs to the BolA IbaG family
KC397_13325	COG3113	response to antibiotic
KC397_13330	COG2854	intermembrane phospholipid transfer
KC397_13335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KC397_13340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KC397_13345	COG1127	ABC transporter
KC397_13355	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KC397_13355	COG0517	IMP dehydrogenase activity
KC397_13360	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KC397_13370	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KC397_13375	COG1137	ATPase activity
KC397_13385	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KC397_13390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KC397_13395	COG1660	Displays ATPase and GTPase activities
KC397_13400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KC397_13405	COG2239	Acts as a magnesium transporter
KC397_13410	COG0312	modulator of DNA gyrase
KC397_13415	COG3028	Belongs to the UPF0307 family
KC397_13420	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KC397_13425	COG1178	ABC-type Fe3 transport system permease component
KC397_13435	COG0163	prenyltransferase activity
KC397_13440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KC397_13445	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KC397_13450	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KC397_13455	COG2105	PFAM AIG2 family protein
KC397_13465	COG0729	surface antigen
KC397_13470	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KC397_13475	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KC397_13490	COG0577	efflux transmembrane transporter activity
KC397_13490	COG1136	(ABC) transporter
KC397_13510	COG0529	Catalyzes the synthesis of activated sulfate
KC397_13515	COG0490	domain, Protein
KC397_13515	COG0471	metal ion transport
KC397_13520	COG2895	sulfate adenylyltransferase (ATP) activity
KC397_13525	COG0175	sulfate reduction
KC397_13530	COG1648	precorrin-2 dehydrogenase activity
KC397_13530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KC397_13535	COG0737	Belongs to the 5'-nucleotidase family
KC397_13545	COG0513	Belongs to the DEAD box helicase family
KC397_13550	COG2153	protein acetylation
KC397_13555	COG0697	spore germination
KC397_13560	COG3061	Opacity-associated protein A
KC397_13565	COG0545	Peptidyl-prolyl cis-trans isomerase
KC397_13575	COG0203	ribosomal protein L17
KC397_13580	COG0202	RNA polymerase activity
KC397_13585	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KC397_13590	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KC397_13595	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KC397_13600	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KC397_13605	COG0201	protein transport
KC397_13610	COG0200	Binds to the 23S rRNA
KC397_13615	COG1841	ribosomal large subunit assembly
KC397_13625	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KC397_13635	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KC397_13640	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KC397_13645	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KC397_13650	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KC397_13655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KC397_13660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KC397_13665	COG0255	Belongs to the universal ribosomal protein uL29 family
KC397_13670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KC397_13680	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KC397_13685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KC397_13690	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KC397_13695	COG0089	rRNA binding
KC397_13700	COG0088	Forms part of the polypeptide exit tunnel
KC397_13705	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KC397_13710	COG0051	transcription antitermination factor activity, RNA binding
KC397_13715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KC397_13720	COG0557	exoribonuclease II activity
KC397_13725	COG3083	sulfuric ester hydrolase activity
KC397_13730	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KC397_13735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KC397_13745	COG1047	Peptidyl-prolyl cis-trans
KC397_13750	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KC397_13760	COG2249	NAD(P)H dehydrogenase (quinone) activity
KC397_13765	COG0488	(ABC) transporter
KC397_13775	COG0429	hydrolase of the alpha beta-hydrolase fold
KC397_13785	COG3954	Phosphoribulokinase
KC397_13800	COG1012	belongs to the aldehyde dehydrogenase family
KC397_13810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KC397_13820	COG0446	pyridine nucleotide-disulphide oxidoreductase
KC397_13830	COG0180	Tryptophanyl-tRNA synthetase
KC397_13840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KC397_13845	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KC397_13855	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KC397_13890	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KC397_13900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KC397_13900	COG0678	peroxiredoxin activity
KC397_13910	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KC397_13910	COG0165	Argininosuccinate lyase
KC397_13915	COG0137	argininosuccinate synthase activity
KC397_13920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KC397_13925	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KC397_13930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KC397_13935	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KC397_13940	COG1695	Transcriptional regulator
KC397_13945	COG1045	serine acetyltransferase
KC397_13950	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KC397_13955	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KC397_13960	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KC397_13965	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KC397_13970	COG1053	succinate dehydrogenase
KC397_13975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KC397_13980	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KC397_13990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KC397_13995	COG1509	lysine 2,3-aminomutase activity
KC397_14000	COG1285	pathogenesis
KC397_14010	COG1119	ATPase activity
KC397_14020	COG3344	reverse transcriptase
KC397_14025	COG0459	protein refolding
KC397_14055	COG0149	triose-phosphate isomerase activity
KC397_14060	COG0534	Mate efflux family protein
KC397_14065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KC397_14070	COG1575	Belongs to the MenA family. Type 1 subfamily
KC397_14075	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KC397_14080	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KC397_14090	COG1609	Transcriptional regulator
KC397_14095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KC397_14100	COG0254	rRNA binding
KC397_14105	COG0281	malic enzyme
KC397_14110	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
KC397_14115	COG0626	cystathionine gamma-synthase activity
KC397_14120	COG0460	homoserine dehydrogenase
KC397_14120	COG0527	aspartate kinase activity
KC397_14125	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KC397_14130	COG3074	FtsZ-dependent cytokinesis
KC397_14135	COG1494	fructose-1,6-bisphosphatase
KC397_14140	COG0205	6-phosphofructokinase activity
KC397_14145	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KC397_14155	COG0745	RESPONSE REGULATOR receiver
KC397_14160	COG2205	protein histidine kinase activity
KC397_14165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KC397_14170	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KC397_14175	COG3030	protein affecting phage T7 exclusion by the F plasmid
KC397_14185	COG1027	Aspartate ammonia-lyase
KC397_14190	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KC397_14195	COG1288	antiporter activity
KC397_14210	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KC397_14215	COG0540	Belongs to the ATCase OTCase family
KC397_14220	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KC397_14230	COG4232	protein-disulfide reductase activity
KC397_14250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KC397_14255	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KC397_14260	COG0194	GDP metabolic process
KC397_14265	COG1758	RNA polymerase activity
KC397_14270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KC397_14275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KC397_14280	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KC397_14285	COG2233	PERMEase
KC397_14300	COG0800	Aldolase
KC397_14305	COG2610	gluconate transmembrane transporter activity
KC397_14310	COG3265	gluconokinase activity
KC397_14315	COG0129	dihydroxy-acid dehydratase activity
KC397_14320	COG1609	Transcriptional regulator
KC397_14325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KC397_14335	COG2183	response to ionizing radiation
KC397_14350	COG1040	competence protein
KC397_14360	COG0494	nUDIX hydrolase
KC397_14365	COG1218	3'(2'),5'-bisphosphate nucleotidase
KC397_14375	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KC397_14380	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KC397_14385	COG3156	type II secretion system protein K
KC397_14390	COG4795	General secretion pathway protein
KC397_14395	COG2165	general secretion pathway protein
KC397_14400	COG2165	general secretion pathway protein
KC397_14405	COG2165	general secretion pathway protein
KC397_14410	COG1459	type II secretion system
KC397_14415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KC397_14425	COG3031	protein transport across the cell outer membrane
KC397_14430	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KC397_14435	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KC397_14440	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KC397_14445	COG2982	Protein involved in outer membrane biogenesis
KC397_14450	COG0456	acetyltransferase
KC397_14455	COG1490	D-aminoacyl-tRNA deacylase activity
KC397_14475	COG1217	gtp-binding protein TYPA
KC397_14480	COG0174	glutamine synthetase
KC397_14490	COG3852	Histidine kinase
KC397_14495	COG2204	response regulator
KC397_14500	COG5001	Diguanylate cyclase
KC397_14500	COG3300	MHYT domain
KC397_14505	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KC397_14565	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KC397_14575	COG4206	TonB-dependent receptor
KC397_14580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KC397_14595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KC397_14600	COG0534	Mate efflux family protein
KC397_14610	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KC397_14615	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KC397_14620	COG2937	Belongs to the GPAT DAPAT family
KC397_14625	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KC397_14630	COG3161	chorismate lyase activity
KC397_14635	COG1580	Controls the rotational direction of flagella during chemotaxis
KC397_14640	COG0705	Rhomboid family
KC397_14645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KC397_14650	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KC397_14655	COG2177	Part of the ABC transporter FtsEX involved in
KC397_14660	COG2884	Cell division ATP-binding protein ftsE
KC397_14665	COG0552	protein localization to endoplasmic reticulum
KC397_14670	COG0742	ribosomal rna small subunit methyltransferase
KC397_14680	COG2095	MarC family integral membrane protein
KC397_14710	COG0783	Belongs to the Dps family
KC397_14725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KC397_14730	COG0640	Transcriptional regulator
KC397_14735	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KC397_14740	COG1280	lysine exporter protein (LysE YggA)
KC397_14745	COG2267	carboxylic ester hydrolase activity
KC397_14750	COG0561	phosphatase activity
KC397_14765	COG3148	PFAM DTW domain containing protein
KC397_14770	COG3287	FIST C domain
KC397_14770	COG2200	EAL domain
KC397_14770	COG2199	diguanylate cyclase activity
KC397_14775	COG1011	Hydrolase
KC397_14780	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KC397_14790	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KC397_14795	COG0019	diaminopimelate decarboxylase activity
KC397_14805	COG1965	Belongs to the frataxin family
KC397_14810	COG3072	Adenylate cyclase
KC397_14825	COG2959	enzyme of heme biosynthesis
KC397_14830	COG3071	HemY protein
KC397_14835	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KC397_14865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KC397_14865	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KC397_14880	COG0084	hydrolase, TatD family'
KC397_14885	COG0805	protein transport
KC397_14890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KC397_14895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KC397_14900	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KC397_14905	COG3165	ubiquinone biosynthetic process from chorismate
KC397_14910	COG2226	methyltransferase
KC397_14915	COG1322	Protein conserved in bacteria
KC397_14940	COG2160	L-arabinose isomerase activity
KC397_14945	COG0235	Class ii aldolase
KC397_14950	COG1069	ribulokinase activity
KC397_14955	COG1879	ABC-type sugar transport system periplasmic component
KC397_14960	COG1129	ABC transporter
KC397_14965	COG1172	Belongs to the binding-protein-dependent transport system permease family
KC397_14970	COG2081	HI0933 family
KC397_14980	COG1528	Iron-storage protein
KC397_14985	COG0589	response to stress
KC397_14990	COG0697	spore germination
KC397_15005	COG5001	Diguanylate cyclase
KC397_15005	COG5002	protein histidine kinase activity
KC397_15010	COG1522	sequence-specific DNA binding
KC397_15030	COG0006	proline dipeptidase activity
KC397_15030	COG0006	proline dipeptidase activity
KC397_15035	COG1309	transcriptional regulator
KC397_15040	COG1012	belongs to the aldehyde dehydrogenase family
KC397_15060	COG0517	IMP dehydrogenase activity
KC397_15060	COG4175	Glycine betaine
KC397_15065	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KC397_15070	COG2022	thiamine diphosphate biosynthetic process
KC397_15080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KC397_15085	COG0352	thiamine-phosphate diphosphorylase activity
KC397_15090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KC397_15095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KC397_15100	COG2132	Multicopper oxidase
KC397_15155	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KC397_15160	COG1739	Uncharacterized protein family UPF0029
KC397_15170	COG0183	Belongs to the thiolase family
KC397_15175	COG0583	DNA-binding transcription factor activity
KC397_15180	COG2814	Major facilitator Superfamily
KC397_15185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KC397_15190	COG0765	amino acid transport
KC397_15200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KC397_15205	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KC397_15210	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KC397_15215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KC397_15220	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KC397_15225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KC397_15240	COG3312	ion transport
KC397_15245	COG1475	DNA binding
KC397_15250	COG1192	Involved in chromosome partitioning
KC397_15255	COG0357	Ribosomal RNA small subunit methyltransferase G
KC397_15260	COG0445	tRNA wobble uridine modification
KC397_15265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KC397_15270	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KC397_15275	COG0706	membrane insertase activity
KC397_15290	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KC397_15295	COG1126	abc transporter atp-binding protein
KC397_15325	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KC397_15335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KC397_15375	COG3842	ATPase activity
KC397_15385	COG1175	transmembrane transport
KC397_15390	COG3833	ABC-type maltose transport systems, permease component
KC397_15415	COG1349	DNA-binding transcription factor activity
KC397_15435	COG2354	Protein conserved in bacteria
KC397_15440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KC397_15445	COG0418	dihydroorotase activity
KC397_15450	COG0633	Ferredoxin
KC397_15450	COG3217	Mosc domain protein beta barrel domain protein
KC397_15480	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KC397_15485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KC397_15495	COG0848	biopolymer transport protein
KC397_15500	COG0811	peptide transport
KC397_15505	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KC397_15510	COG3721	Heme iron utilization protein
KC397_15515	COG0748	coenzyme F420 binding
KC397_15525	COG0531	amino acid
KC397_15530	COG1522	sequence-specific DNA binding
KC397_15555	COG1151	hydroxylamine reductase activity
KC397_15560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KC397_15565	COG2200	EAL domain
KC397_15590	COG5002	protein histidine kinase activity
KC397_15590	COG2205	protein histidine kinase activity
KC397_15590	COG0784	Response regulator, receiver
KC397_15595	COG5001	Diguanylate cyclase
KC397_15595	COG3300	MHYT domain
KC397_15610	COG1765	OsmC-like protein
KC397_15645	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KC397_15655	COG1022	Amp-dependent synthetase and ligase
KC397_15680	COG0642	Histidine kinase
KC397_15690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KC397_15695	COG3186	Phenylalanine-4-hydroxylase
KC397_15700	COG2154	pterin-4-alpha-carbinolamine dehydratase
KC397_15705	COG0534	Mate efflux family protein
KC397_15715	COG0861	Integral membrane protein TerC family
KC397_15725	COG0456	acetyltransferase
KC397_15730	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KC397_15735	COG0662	Cupin 2, conserved barrel domain protein
KC397_15740	COG0527	aspartate kinase activity
KC397_15745	COG0561	phosphatase activity
KC397_15755	COG0583	DNA-binding transcription factor activity
KC397_15765	COG0784	Response regulator, receiver
KC397_15765	COG3437	response regulator, receiver
KC397_15775	COG0113	porphobilinogen synthase activity
KC397_15785	COG0459	protein refolding
KC397_15790	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KC397_15795	COG2239	Acts as a magnesium transporter
KC397_15805	COG0840	transmembrane signaling receptor activity
KC397_15815	COG2113	Glycine betaine
KC397_15820	COG4176	ABC-type proline glycine betaine transport system permease component
KC397_15825	COG4175	Glycine betaine
KC397_15835	COG1166	arginine decarboxylase activity
KC397_15845	COG1522	sequence-specific DNA binding
KC397_15860	COG0765	amino acid transport
KC397_15870	COG1686	Belongs to the peptidase S11 family
KC397_15885	COG1566	PFAM secretion protein HlyD family protein
KC397_15930	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KC397_15940	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KC397_15945	COG2070	2-Nitropropane dioxygenase
KC397_15950	COG1280	lysine exporter protein (LysE YggA)
KC397_15955	COG0513	Belongs to the DEAD box helicase family
KC397_15970	COG0840	transmembrane signaling receptor activity
KC397_15985	COG2985	domain, Protein
KC397_15995	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KC397_16015	COG1280	lysine exporter protein (LysE YggA)
KC397_16060	COG3122	Protein conserved in bacteria
KC397_16080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KC397_16080	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KC397_16085	COG0509	glycine decarboxylation via glycine cleavage system
KC397_16100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KC397_16110	COG3706	GGDEF domain
KC397_16115	COG5001	Diguanylate cyclase
KC397_16120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KC397_16135	COG0546	phosphoglycolate phosphatase activity
KC397_16155	COG0484	heat shock protein binding
KC397_16165	COG5001	Diguanylate cyclase
KC397_16165	COG1716	ATPase activity
KC397_16170	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KC397_16180	COG4181	ATPase activity
KC397_16185	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KC397_16195	COG1984	allophanate hydrolase subunit 2
KC397_16205	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KC397_16210	COG5002	protein histidine kinase activity
KC397_16210	COG5001	Diguanylate cyclase
KC397_16210	COG3447	MASE1 domain protein
KC397_16215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KC397_16220	COG0840	transmembrane signaling receptor activity
KC397_16225	COG0814	amino acid
KC397_16230	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
KC397_16235	COG0513	Belongs to the DEAD box helicase family
KC397_16240	COG1309	transcriptional regulator
KC397_16250	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
KC397_16265	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KC397_16305	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KC397_16315	COG0463	Glycosyl transferase, family 2
KC397_16325	COG0583	DNA-binding transcription factor activity
KC397_16330	COG0697	spore germination
KC397_16335	COG1917	Cupin 2, conserved barrel domain protein
KC397_16335	COG2207	Transcriptional regulator
KC397_16360	COG0330	HflC and HflK could
KC397_16370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KC397_16385	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KC397_16390	COG0583	DNA-binding transcription factor activity
KC397_16395	COG3781	membrane
KC397_16405	COG1271	oxidase subunit
KC397_16410	COG1294	oxidase, subunit
KC397_16415	COG0800	Aldolase
KC397_16420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KC397_16425	COG1904	glucuronate isomerase
KC397_16430	COG0246	Mannitol dehydrogenase
KC397_16445	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KC397_16455	COG2186	Transcriptional regulator
KC397_16465	COG2390	Transcriptional regulator
KC397_16475	COG1070	Carbohydrate kinase
KC397_16485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KC397_16500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KC397_16510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KC397_16520	COG1120	ATPase activity
KC397_16525	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KC397_16560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KC397_16590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KC397_16600	COG2116	formate transmembrane transporter activity
KC397_16605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KC397_16605	COG1648	precorrin-2 dehydrogenase activity
KC397_16635	COG3118	belongs to the thioredoxin family
KC397_16640	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KC397_16655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KC397_16665	COG1596	polysaccharide export
KC397_16690	COG0438	transferase activity, transferring glycosyl groups
KC397_16695	COG0297	glycogen (starch) synthase activity
KC397_16695	COG0438	transferase activity, transferring glycosyl groups
KC397_16710	COG0247	lactate metabolic process
KC397_16715	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
KC397_16720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KC397_16725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KC397_16730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KC397_16760	COG3132	Protein of unknown function, DUF480
KC397_16765	COG2827	Endonuclease containing a URI domain
KC397_16775	COG1879	ABC-type sugar transport system periplasmic component
KC397_16780	COG0784	Response regulator, receiver
KC397_16780	COG5002	protein histidine kinase activity
KC397_16800	COG1492	cobalamin metabolic process
KC397_16805	COG0725	ABC transporter, periplasmic molybdate-binding protein
KC397_16810	COG4149	molybdate abc transporter
KC397_16815	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KC397_16835	COG1289	transmembrane transporter activity
KC397_16875	COG0210	DNA helicase
KC397_16880	COG1335	isochorismatase
KC397_16885	COG1803	Methylglyoxal synthase
KC397_16890	COG1879	ABC-type sugar transport system periplasmic component
KC397_16895	COG0784	Response regulator, receiver
KC397_16895	COG2198	Histidine kinase
KC397_16895	COG2205	protein histidine kinase activity
KC397_16900	COG0469	pyruvate kinase activity
KC397_16905	COG2271	Major facilitator Superfamily
KC397_16930	COG1979	alcohol dehydrogenase
KC397_16935	COG2207	Transcriptional regulator
KC397_16950	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KC397_16975	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KC397_16980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KC397_16990	COG0183	Belongs to the thiolase family
KC397_17030	COG0243	molybdopterin cofactor binding
KC397_17045	COG3850	Histidine kinase
KC397_17050	COG2197	response regulator
KC397_17055	COG3069	C4-dicarboxylate transmembrane transporter activity
KC397_17070	COG2814	Major facilitator Superfamily
KC397_17075	COG0840	transmembrane signaling receptor activity
KC397_17080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KC397_17085	COG0545	Peptidyl-prolyl cis-trans isomerase
KC397_17100	COG0840	transmembrane signaling receptor activity
KC397_17105	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KC397_17120	COG2897	thiosulfate sulfurtransferase activity
KC397_17125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KC397_17135	COG0302	gtp cyclohydrolase
KC397_17140	COG0531	amino acid
KC397_17150	COG4303	Ethanolamine ammonia lyase large subunit
KC397_17160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KC397_17160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KC397_17165	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KC397_17170	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KC397_17185	COG1011	Hydrolase
KC397_17190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KC397_17205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KC397_17210	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KC397_17220	COG3842	ATPase activity
KC397_17240	COG2866	Carboxypeptidase
KC397_17265	COG4166	transmembrane transport
KC397_17270	COG4174	ABC transporter (Permease)
KC397_17275	COG4239	(ABC) transporter, permease
KC397_17280	COG4172	Belongs to the ABC transporter superfamily
KC397_17305	COG2203	Gaf domain
KC397_17305	COG3706	GGDEF domain
KC397_17305	COG4251	negative regulation of phosphorylation
KC397_17305	COG5001	Diguanylate cyclase
KC397_17315	COG3706	GGDEF domain
KC397_17325	COG2501	S4 domain
KC397_17365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KC397_17390	COG1979	alcohol dehydrogenase
KC397_17395	COG2207	Transcriptional regulator
KC397_17415	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KC397_17425	COG0488	(ABC) transporter
KC397_17435	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KC397_17445	COG2814	Major facilitator Superfamily
KC397_17465	COG3710	Transcriptional regulator
KC397_17495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KC397_17510	COG2233	PERMEase
KC397_17530	COG1953	Uracil, thiamine, allantoin
KC397_17540	COG0765	amino acid transport
KC397_17545	COG0765	amino acid transport
KC397_17575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KC397_17600	COG0402	S-adenosylhomocysteine deaminase activity
KC397_17605	COG2351	hydroxyisourate hydrolase activity
KC397_17635	COG1079	Belongs to the binding-protein-dependent transport system permease family
KC397_17640	COG4603	Belongs to the binding-protein-dependent transport system permease family
KC397_17645	COG3845	ABC transporter
KC397_17650	COG1309	transcriptional regulator
KC397_17685	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KC397_17690	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KC397_17700	COG0745	RESPONSE REGULATOR receiver
KC397_17715	COG3140	Belongs to the UPF0181 family
KC397_17720	COG0023	Translation Initiation Factor
KC397_17745	COG0045	succinate-CoA ligase (ADP-forming) activity
KC397_17745	COG1042	CoA-binding domain protein
KC397_17745	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KC397_17750	COG0583	DNA-binding transcription factor activity
KC397_17755	COG4771	TonB-dependent receptor
KC397_17755	COG1629	transport
KC397_17775	COG2050	protein possibly involved in aromatic compounds catabolism
KC397_17785	COG2824	Alkylphosphonate utilization operon protein PhnA
KC397_17795	COG0861	Integral membrane protein TerC family
KC397_17800	COG0737	Belongs to the 5'-nucleotidase family
KC397_17805	COG3593	DNA synthesis involved in DNA repair
KC397_17815	COG0583	DNA-binding transcription factor activity
KC397_17820	COG2116	formate transmembrane transporter activity
KC397_17825	COG2353	YceI-like domain
KC397_17830	COG3038	cytochrome b561
KC397_17855	COG5001	Diguanylate cyclase
KC397_17865	COG0243	molybdopterin cofactor binding
KC397_17870	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KC397_17875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KC397_17875	COG0543	2 iron, 2 sulfur cluster binding
KC397_17885	COG3437	response regulator, receiver
KC397_17895	COG2207	Transcriptional regulator
KC397_17905	COG0523	cobalamin synthesis protein
KC397_17920	COG0156	8-amino-7-oxononanoate synthase activity
KC397_17925	COG0784	Response regulator, receiver
KC397_17925	COG2205	protein histidine kinase activity
KC397_17930	COG0419	ATPase involved in DNA repair
KC397_17940	COG1609	Transcriptional regulator
KC397_17945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KC397_17945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KC397_17950	COG1105	Belongs to the carbohydrate kinase PfkB family
KC397_17955	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KC397_17955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KC397_17955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KC397_17960	COG4067	protein conserved in archaea
KC397_17960	COG0189	ligase activity
KC397_17970	COG0602	queuosine metabolic process
KC397_17975	COG1328	CTP reductase activity
KC397_18030	COG1280	lysine exporter protein (LysE YggA)
KC397_18035	COG0745	RESPONSE REGULATOR receiver
KC397_18045	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KC397_18055	COG0583	DNA-binding transcription factor activity
KC397_18070	COG1309	transcriptional regulator
KC397_18075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KC397_18105	COG1335	isochorismatase
KC397_18110	COG4977	sequence-specific DNA binding
KC397_18115	COG0456	acetyltransferase
KC397_18125	COG1280	lysine exporter protein (LysE YggA)
KC397_18130	COG0494	nUDIX hydrolase
KC397_18140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KC397_18170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KC397_18190	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_18200	COG0454	-acetyltransferase
KC397_18260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KC397_18265	COG0789	Transcriptional regulator
KC397_18325	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_18335	COG4628	conserved protein (DUF2132)
KC397_18355	COG0672	)-iron permease
KC397_18375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KC397_18380	COG0513	Belongs to the DEAD box helicase family
KC397_18395	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KC397_18405	COG0583	DNA-binding transcription factor activity
KC397_18410	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KC397_18445	COG1538	Outer membrane efflux protein
KC397_18455	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
KC397_18470	COG2015	COG2015, Alkyl sulfatase and related hydrolases
KC397_18475	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KC397_18480	COG1349	DNA-binding transcription factor activity
KC397_18485	COG0110	maltose O-acetyltransferase activity
KC397_18490	COG3706	GGDEF domain
KC397_18500	COG2162	N-hydroxyarylamine O-acetyltransferase activity
KC397_18505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KC397_18515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KC397_18525	COG0747	negative chemotaxis
KC397_18530	COG4172	Belongs to the ABC transporter superfamily
KC397_18540	COG3437	response regulator, receiver
KC397_18545	COG0784	Response regulator, receiver
KC397_18545	COG2198	Histidine kinase
KC397_18545	COG2205	protein histidine kinase activity
KC397_18555	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KC397_18575	COG1595	DNA-templated transcription, initiation
KC397_18590	COG0633	Ferredoxin
KC397_18590	COG3217	Mosc domain protein beta barrel domain protein
KC397_18600	COG0583	DNA-binding transcription factor activity
KC397_18615	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KC397_18630	COG2423	ornithine cyclodeaminase activity
KC397_18640	COG4145	pantothenate transmembrane transporter activity
KC397_18645	COG0583	DNA-binding transcription factor activity
KC397_18650	COG0435	Glutathione S-transferase
KC397_18655	COG0400	carboxylic ester hydrolase activity
KC397_18660	COG1280	lysine exporter protein (LysE YggA)
KC397_18675	COG1473	amidohydrolase
KC397_18695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KC397_18700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KC397_18705	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KC397_18715	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KC397_18730	COG2721	sulfolactate sulfo-lyase activity
KC397_18795	COG0784	Response regulator, receiver
KC397_18795	COG2205	protein histidine kinase activity
KC397_18795	COG2198	Histidine kinase
KC397_18800	COG2204	response regulator
KC397_18805	COG0438	transferase activity, transferring glycosyl groups
KC397_18840	COG0438	transferase activity, transferring glycosyl groups
KC397_18850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KC397_18855	COG0438	transferase activity, transferring glycosyl groups
KC397_18880	COG0625	glutathione transferase activity
KC397_18890	COG1472	Belongs to the glycosyl hydrolase 3 family
KC397_18900	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KC397_18910	COG0573	inorganic phosphate transmembrane transporter activity
KC397_18915	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KC397_18935	COG1464	Belongs to the NlpA lipoprotein family
KC397_18940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KC397_18940	COG0512	Glutamine amidotransferase of anthranilate synthase
KC397_18960	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KC397_18975	COG0653	protein targeting
KC397_19005	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_19015	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_19025	COG1024	Enoyl-CoA hydratase
KC397_19030	COG1024	Enoyl-CoA hydratase
KC397_19035	COG1960	acyl-CoA dehydrogenase activity
KC397_19045	COG0183	Belongs to the thiolase family
KC397_19055	COG1960	acyl-CoA dehydrogenase activity
KC397_19060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KC397_19080	COG0450	alkyl hydroperoxide reductase
KC397_19115	COG2207	Transcriptional regulator
KC397_19115	COG1609	Transcriptional regulator
KC397_19120	COG1454	alcohol dehydrogenase
KC397_19125	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KC397_19160	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KC397_19175	COG2207	Transcriptional regulator
KC397_19175	COG3708	Transcriptional regulator
KC397_19180	COG4604	ABC transporter, ATP-binding protein
KC397_19185	COG4605	iron ion homeostasis
KC397_19190	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KC397_19195	COG4607	ABC-type enterochelin transport system periplasmic component
KC397_19215	COG5380	lipid catabolic process
KC397_19220	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KC397_19230	COG1522	sequence-specific DNA binding
KC397_19250	COG2814	Major facilitator Superfamily
KC397_19260	COG0840	transmembrane signaling receptor activity
KC397_19275	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KC397_19280	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KC397_19285	COG3279	Response regulator of the LytR AlgR family
KC397_19290	COG3275	phosphorelay sensor kinase activity
KC397_19295	COG4989	oxidoreductase activity
KC397_19310	COG0366	Alpha amylase catalytic
KC397_19315	COG3227	Zinc metalloprotease (Elastase)
KC397_19320	COG3047	cAMP biosynthetic process
KC397_19325	COG0071	Belongs to the small heat shock protein (HSP20) family
KC397_19335	COG0251	oxidation-reduction process
KC397_19345	COG0583	DNA-binding transcription factor activity
KC397_19350	COG2267	carboxylic ester hydrolase activity
KC397_19360	COG1132	(ABC) transporter
KC397_19365	COG1132	(ABC) transporter
KC397_19375	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KC397_19380	COG2246	polysaccharide biosynthetic process
KC397_19390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KC397_19400	COG0242	peptide deformylase activity
KC397_19410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KC397_19415	COG2084	Dehydrogenase
KC397_19425	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KC397_19430	COG0583	DNA-binding transcription factor activity
KC397_19460	COG0582	viral genome integration into host DNA
KC397_19470	COG1278	Cold shock
KC397_19490	COG1063	alcohol dehydrogenase
KC397_19495	COG0156	8-amino-7-oxononanoate synthase activity
KC397_19500	COG1012	belongs to the aldehyde dehydrogenase family
KC397_19505	COG3284	Transcriptional regulator
KC397_19515	COG0346	lactoylglutathione lyase activity
KC397_19535	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KC397_19545	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KC397_19550	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KC397_19555	COG0363	glucosamine-6-phosphate deaminase activity
KC397_19560	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KC397_19575	COG0583	DNA-binding transcription factor activity
KC397_19590	COG0646	methionine synthase
KC397_19590	COG1410	methionine synthase
KC397_19595	COG0531	amino acid
KC397_19610	COG1473	amidohydrolase
KC397_19615	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KC397_19620	COG1929	Belongs to the glycerate kinase type-1 family
KC397_19625	COG2610	gluconate transmembrane transporter activity
KC397_19630	COG3835	regulator
KC397_19635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KC397_19640	COG4533	DNA binding
KC397_19655	COG0840	transmembrane signaling receptor activity
KC397_19710	COG4964	Belongs to the GSP D family
KC397_19750	COG0798	PFAM Bile acid sodium symporter
KC397_19775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KC397_19780	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KC397_19780	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KC397_19790	COG0745	RESPONSE REGULATOR receiver
KC397_19810	COG3036	rescue of stalled ribosome
KC397_19815	COG1278	Cold shock
KC397_19820	COG4681	YaeQ
KC397_19830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KC397_19830	COG1017	nitric oxide dioxygenase activity
KC397_19835	COG3604	Transcriptional regulator
KC397_19845	COG2195	Cleaves the N-terminal amino acid of tripeptides
KC397_19850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KC397_19860	COG0366	Alpha amylase catalytic
KC397_19880	COG0714	Associated with various cellular activities
KC397_19900	COG2304	oxidoreductase activity
KC397_19915	COG3706	GGDEF domain
KC397_19925	COG0784	Response regulator, receiver
KC397_19925	COG2205	protein histidine kinase activity
KC397_19925	COG5002	protein histidine kinase activity
KC397_19940	COG3724	N-succinylarginine dihydrolase activity
KC397_19945	COG1012	belongs to the aldehyde dehydrogenase family
KC397_19970	COG4948	Mandelate Racemase Muconate Lactonizing
KC397_19995	COG0583	DNA-binding transcription factor activity
KC397_20020	COG3171	Protein conserved in bacteria
KC397_20025	COG0589	response to stress
KC397_20035	COG3530	Putative quorum-sensing-regulated virulence factor
KC397_20045	COG0579	oxidoreductase
KC397_20060	COG2204	response regulator
KC397_20070	COG1929	Belongs to the glycerate kinase type-1 family
KC397_20075	COG0383	alpha-mannosidase activity
KC397_20080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KC397_20080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KC397_20080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KC397_20085	COG2188	Transcriptional regulator
KC397_20110	COG5001	Diguanylate cyclase
KC397_20110	COG3300	MHYT domain
KC397_20115	COG2271	Major facilitator Superfamily
KC397_20120	COG0584	glycerophosphoryl diester phosphodiesterase
KC397_20125	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KC397_20130	COG0583	DNA-binding transcription factor activity
KC397_20140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KC397_20145	COG1879	ABC-type sugar transport system periplasmic component
KC397_20150	COG1172	Belongs to the binding-protein-dependent transport system permease family
KC397_20155	COG1129	ABC transporter
KC397_20160	COG1869	D-ribose catabolic process
KC397_20180	COG3409	Peptidoglycan-binding domain 1 protein
KC397_20180	COG3501	Rhs element vgr protein
KC397_20205	COG3829	transcription factor binding
KC397_20275	COG1280	lysine exporter protein (LysE YggA)
KC397_20280	COG1846	Transcriptional regulator
KC397_20285	COG1230	cation diffusion facilitator family transporter
KC397_20295	COG0564	pseudouridine synthase activity
KC397_20300	COG1309	transcriptional regulator
KC397_20305	COG2130	NADP-dependent
KC397_20320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KC397_20350	COG3842	ATPase activity
KC397_20360	COG2200	EAL domain
KC397_20365	COG0656	L-ascorbic acid biosynthetic process
KC397_20370	COG1902	pentaerythritol trinitrate reductase activity
KC397_20375	COG0583	DNA-binding transcription factor activity
KC397_20380	COG2814	Major facilitator Superfamily
KC397_20400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KC397_20415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KC397_20425	COG4702	Belongs to the UPF0303 family
KC397_20430	COG0673	inositol 2-dehydrogenase activity
KC397_20435	COG1349	DNA-binding transcription factor activity
KC397_20440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KC397_20460	COG3240	lipase activity
KC397_20465	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_20470	COG0583	DNA-binding transcription factor activity
KC397_20480	COG1120	ATPase activity
KC397_20485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KC397_20490	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KC397_20495	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
KC397_20500	COG4774	siderophore transport
KC397_20525	COG0840	transmembrane signaling receptor activity
KC397_20530	COG3384	dioxygenase
KC397_20535	COG0583	DNA-binding transcription factor activity
KC397_20545	COG1342	Belongs to the UPF0251 family
KC397_20550	COG0778	Nitroreductase
KC397_20555	COG0583	DNA-binding transcription factor activity
KC397_20565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KC397_20570	COG0697	spore germination
KC397_20585	COG2814	Major facilitator Superfamily
KC397_20590	COG0583	DNA-binding transcription factor activity
KC397_20595	COG5001	Diguanylate cyclase
KC397_20595	COG3300	MHYT domain
KC397_20600	COG0739	heme binding
KC397_20615	COG0659	secondary active sulfate transmembrane transporter activity
KC397_20620	COG3314	Sporulation integral membrane protein YlbJ
KC397_20630	COG2199	diguanylate cyclase activity
KC397_20635	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KC397_20640	COG0581	inorganic phosphate transmembrane transporter activity
KC397_20645	COG0573	inorganic phosphate transmembrane transporter activity
KC397_20650	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KC397_20655	COG0840	transmembrane signaling receptor activity
KC397_20660	COG0513	Belongs to the DEAD box helicase family
KC397_20670	COG1376	ErfK ybiS ycfS ynhG family protein
KC397_20670	COG1388	LysM domain
KC397_20675	COG0415	Belongs to the DNA photolyase family
KC397_20685	COG3272	Protein of unknown function (DUF1722)
KC397_20690	COG0813	purine-nucleoside phosphorylase activity
KC397_20715	COG1566	PFAM secretion protein HlyD family protein
KC397_20750	COG0786	glutamate:sodium symporter activity
KC397_20765	COG1999	signal sequence binding
KC397_20775	COG1162	GTPase activity
KC397_20780	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KC397_20795	COG4580	involved in the transport of maltose and maltodextrins
KC397_20810	COG1132	(ABC) transporter
KC397_20820	COG0671	phosphoesterase, PA-phosphatase related
KC397_20830	COG3383	formate dehydrogenase (NAD+) activity
KC397_20845	COG0840	transmembrane signaling receptor activity
KC397_20855	COG1131	(ABC) transporter
KC397_20860	COG2188	Transcriptional regulator
KC397_20870	COG3033	Beta-eliminating lyase
KC397_20875	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KC397_20880	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KC397_20890	COG0471	metal ion transport
KC397_20915	COG3788	relative of glutathione S-transferase, MAPEG superfamily
KC397_20935	COG3501	Rhs element vgr protein
KC397_20945	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KC397_20950	COG1640	4-alpha-glucanotransferase
KC397_20955	COG0058	SHG alpha-glucan phosphorylase activity
KC397_20960	COG2909	trisaccharide binding
KC397_20975	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KC397_20980	COG1845	cytochrome c oxidase, subunit III
KC397_20985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KC397_20990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KC397_21005	COG2084	Dehydrogenase
KC397_21020	COG0217	transcriptional regulatory protein
KC397_21055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KC397_21060	COG1444	tRNA N-acetyltransferase activity
KC397_21075	COG0643	Histidine kinase
KC397_21075	COG2198	Histidine kinase
KC397_21085	COG0835	chemotaxis
KC397_21090	COG0840	transmembrane signaling receptor activity
KC397_21095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KC397_21105	COG2201	protein-glutamate methylesterase activity
KC397_21120	COG0745	RESPONSE REGULATOR receiver
KC397_21160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KC397_21195	COG0840	transmembrane signaling receptor activity
KC397_21215	COG0859	PFAM glycosyl transferase family 9
KC397_21220	COG0513	Belongs to the DEAD box helicase family
KC397_21225	COG0477	Major facilitator Superfamily
KC397_21230	COG0583	DNA-binding transcription factor activity
KC397_21235	COG2226	methyltransferase
KC397_21250	COG0724	RNA recognition motif
KC397_21255	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KC397_21260	COG1522	sequence-specific DNA binding
KC397_21265	COG2610	gluconate transmembrane transporter activity
KC397_21270	COG3622	Belongs to the hyi family
KC397_21275	COG0235	Class ii aldolase
KC397_21280	COG3395	kinase activity
KC397_21285	COG2084	Dehydrogenase
KC397_21290	COG1349	DNA-binding transcription factor activity
KC397_21305	COG0583	DNA-binding transcription factor activity
KC397_21310	COG2910	NAD(P)H-binding
KC397_21325	COG1335	isochorismatase
KC397_21330	COG2207	Transcriptional regulator
KC397_21330	COG1609	Transcriptional regulator
KC397_21345	COG2329	Antibiotic biosynthesis monooxygenase
KC397_21350	COG3304	Inner membrane component domain
KC397_21360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KC397_21395	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KC397_21415	COG1619	proteins homologs of microcin C7 resistance protein MccF
KC397_21455	COG2176	DNA-directed DNA polymerase activity
KC397_21475	COG0443	Heat shock 70 kDa protein
KC397_21480	COG0095	Lipoate-protein ligase
KC397_21495	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KC397_21500	COG1473	amidohydrolase
KC397_21515	COG3722	fumarate hydratase activity
KC397_21525	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KC397_21525	COG2213	PTS system mannitol-specific
KC397_21530	COG0739	heme binding
KC397_21545	COG0363	glucosamine-6-phosphate deaminase activity
KC397_21570	COG0402	S-adenosylhomocysteine deaminase activity
KC397_21575	COG2259	Doxx family
KC397_21580	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KC397_21585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KC397_21595	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KC397_21600	COG1301	dicarboxylic acid transport
KC397_21615	COG2169	Transcriptional regulator
KC397_21615	COG1917	Cupin 2, conserved barrel domain protein
KC397_21650	COG1764	response to oxidative stress
KC397_21655	COG1846	Transcriptional regulator
KC397_21660	COG0179	Fumarylacetoacetate (FAA) hydrolase
KC397_21680	COG1280	lysine exporter protein (LysE YggA)
KC397_21690	COG1902	pentaerythritol trinitrate reductase activity
KC397_21695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KC397_21705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KC397_21740	COG0109	protoheme IX farnesyltransferase activity
KC397_21755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KC397_21765	COG5002	protein histidine kinase activity
KC397_21765	COG5001	Diguanylate cyclase
KC397_21765	COG3447	MASE1 domain protein
KC397_21785	COG2169	Transcriptional regulator
KC397_21805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KC397_21810	COG0697	spore germination
KC397_21815	COG0477	Major facilitator Superfamily
KC397_21820	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KC397_21825	COG0625	glutathione transferase activity
KC397_21835	COG1942	4-Oxalocrotonate Tautomerase
KC397_21850	COG0583	DNA-binding transcription factor activity
KC397_21870	COG3152	Membrane
KC397_21880	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KC397_21890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KC397_21905	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KC397_21920	COG1620	l-lactate permease
KC397_21925	COG0583	DNA-binding transcription factor activity
KC397_21930	COG4172	Belongs to the ABC transporter superfamily
KC397_21940	COG1067	ATP-dependent peptidase activity
KC397_21950	COG2211	Major facilitator Superfamily
KC397_21955	COG0668	transmembrane transport
KC397_21960	COG0569	domain protein
KC397_21965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KC397_21975	COG3123	guanosine phosphorylase activity
KC397_21985	COG2814	Major facilitator Superfamily
KC397_22095	COG2205	protein histidine kinase activity
KC397_22100	COG0745	RESPONSE REGULATOR receiver
KC397_22105	COG1741	Belongs to the pirin family
KC397_22115	COG5001	Diguanylate cyclase
KC397_22140	COG3706	GGDEF domain
KC397_22160	COG3706	GGDEF domain
KC397_22170	COG1846	Transcriptional regulator
KC397_22175	COG2315	Protein conserved in bacteria
KC397_22180	COG0835	chemotaxis
KC397_22180	COG0784	Response regulator, receiver
KC397_22185	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KC397_22195	COG1942	4-Oxalocrotonate Tautomerase
KC397_22210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KC397_22230	COG1522	sequence-specific DNA binding
KC397_22240	COG0393	Putative heavy-metal-binding
KC397_22245	COG0823	Involved in the tonB-independent uptake of proteins
KC397_22250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KC397_22255	COG0534	Mate efflux family protein
KC397_22265	COG1653	transport
KC397_22270	COG3842	ATPase activity
KC397_22275	COG0395	ABC-type sugar transport system, permease component
KC397_22280	COG1175	transmembrane transport
KC397_22300	COG0800	Aldolase
KC397_22305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KC397_22320	COG1917	Cupin 2, conserved barrel domain protein
KC397_22330	COG1028	Short-chain dehydrogenase reductase Sdr
KC397_22335	COG1414	Transcriptional regulator
KC397_22340	COG0517	IMP dehydrogenase activity