locus-tag	class	description
AL536_00020	COG0840	transmembrane signaling receptor activity
AL536_00035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL536_00040	COG0513	Belongs to the DEAD box helicase family
AL536_00050	COG0583	DNA-binding transcription factor activity
AL536_00055	COG2226	methyltransferase
AL536_00070	COG0724	RNA recognition motif
AL536_00075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL536_00080	COG1522	sequence-specific DNA binding
AL536_00085	COG2610	gluconate transmembrane transporter activity
AL536_00090	COG3622	Belongs to the hyi family
AL536_00095	COG0235	Class ii aldolase
AL536_00100	COG3395	kinase activity
AL536_00105	COG2084	Dehydrogenase
AL536_00110	COG1349	DNA-binding transcription factor activity
AL536_00125	COG0583	DNA-binding transcription factor activity
AL536_00130	COG2910	NAD(P)H-binding
AL536_00145	COG1335	isochorismatase
AL536_00165	COG2329	Antibiotic biosynthesis monooxygenase
AL536_00170	COG3304	Inner membrane component domain
AL536_00190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_00215	COG1403	HNH endonuclease
AL536_00225	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL536_00235	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL536_00250	COG0367	asparagine synthase
AL536_00290	COG2176	DNA-directed DNA polymerase activity
AL536_00310	COG0443	Heat shock 70 kDa protein
AL536_00315	COG0095	Lipoate-protein ligase
AL536_00330	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL536_00335	COG1473	amidohydrolase
AL536_00350	COG3722	fumarate hydratase activity
AL536_00360	COG2213	PTS system mannitol-specific
AL536_00360	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_00365	COG0739	heme binding
AL536_00380	COG0363	glucosamine-6-phosphate deaminase activity
AL536_00405	COG0402	S-adenosylhomocysteine deaminase activity
AL536_00410	COG2259	Doxx family
AL536_00415	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL536_00420	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL536_00430	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AL536_00435	COG1301	dicarboxylic acid transport
AL536_00455	COG1917	Cupin 2, conserved barrel domain protein
AL536_00455	COG2169	Transcriptional regulator
AL536_00490	COG1764	response to oxidative stress
AL536_00495	COG1846	Transcriptional regulator
AL536_00500	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL536_00520	COG1280	lysine exporter protein (LysE YggA)
AL536_00530	COG1902	pentaerythritol trinitrate reductase activity
AL536_00535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL536_00545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL536_00575	COG1612	heme a metabolic process
AL536_00580	COG0109	protoheme IX farnesyltransferase activity
AL536_00595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL536_00605	COG3447	MASE1 domain protein
AL536_00605	COG5001	Diguanylate cyclase
AL536_00605	COG5002	protein histidine kinase activity
AL536_00625	COG2169	Transcriptional regulator
AL536_00645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_00650	COG0697	spore germination
AL536_00655	COG3477	response to acidic pH
AL536_00660	COG0477	Major facilitator Superfamily
AL536_00665	COG0625	glutathione transferase activity
AL536_00675	COG1942	4-Oxalocrotonate Tautomerase
AL536_00690	COG0583	DNA-binding transcription factor activity
AL536_00710	COG3152	Membrane
AL536_00720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL536_00730	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL536_00755	COG1304	FMN binding
AL536_00760	COG1620	l-lactate permease
AL536_00765	COG0583	DNA-binding transcription factor activity
AL536_00770	COG4172	Belongs to the ABC transporter superfamily
AL536_00780	COG1067	ATP-dependent peptidase activity
AL536_00785	COG0840	transmembrane signaling receptor activity
AL536_00790	COG2211	Major facilitator Superfamily
AL536_00795	COG0668	transmembrane transport
AL536_00800	COG0569	domain protein
AL536_00805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL536_00815	COG3123	guanosine phosphorylase activity
AL536_00820	COG1741	Belongs to the pirin family
AL536_00830	COG5001	Diguanylate cyclase
AL536_00855	COG3706	GGDEF domain
AL536_00875	COG3706	GGDEF domain
AL536_00885	COG1846	Transcriptional regulator
AL536_00890	COG2315	Protein conserved in bacteria
AL536_00895	COG0784	Response regulator, receiver
AL536_00895	COG0835	chemotaxis
AL536_00900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL536_00915	COG1942	4-Oxalocrotonate Tautomerase
AL536_00935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL536_00955	COG1522	sequence-specific DNA binding
AL536_00965	COG0393	Putative heavy-metal-binding
AL536_00970	COG0823	Involved in the tonB-independent uptake of proteins
AL536_00975	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL536_00980	COG0534	Mate efflux family protein
AL536_00990	COG1653	transport
AL536_00995	COG3842	ATPase activity
AL536_01000	COG0395	ABC-type sugar transport system, permease component
AL536_01005	COG1175	transmembrane transport
AL536_01025	COG0800	Aldolase
AL536_01030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL536_01045	COG1917	Cupin 2, conserved barrel domain protein
AL536_01055	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_01060	COG1414	Transcriptional regulator
AL536_01085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL536_01095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_01135	COG3842	ATPase activity
AL536_01175	COG1349	DNA-binding transcription factor activity
AL536_01195	COG2354	Protein conserved in bacteria
AL536_01200	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL536_01205	COG0418	dihydroorotase activity
AL536_01215	COG0633	Ferredoxin
AL536_01215	COG3217	Mosc domain protein beta barrel domain protein
AL536_01245	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL536_01250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_01260	COG0848	biopolymer transport protein
AL536_01265	COG0811	peptide transport
AL536_01270	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL536_01275	COG3721	Heme iron utilization protein
AL536_01280	COG0748	coenzyme F420 binding
AL536_01290	COG0531	amino acid
AL536_01295	COG1522	sequence-specific DNA binding
AL536_01325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL536_01330	COG2200	EAL domain
AL536_01355	COG0784	Response regulator, receiver
AL536_01355	COG2205	protein histidine kinase activity
AL536_01355	COG5002	protein histidine kinase activity
AL536_01360	COG5001	Diguanylate cyclase
AL536_01360	COG3300	MHYT domain
AL536_01375	COG1765	OsmC-like protein
AL536_01385	COG2171	N-acyltransferase activity
AL536_01410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL536_01440	COG0745	RESPONSE REGULATOR receiver
AL536_01445	COG0642	Histidine kinase
AL536_01455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL536_01460	COG3186	Phenylalanine-4-hydroxylase
AL536_01465	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL536_01470	COG0534	Mate efflux family protein
AL536_01480	COG0861	Integral membrane protein TerC family
AL536_01490	COG0456	acetyltransferase
AL536_01495	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL536_01500	COG0662	Cupin 2, conserved barrel domain protein
AL536_01505	COG0527	aspartate kinase activity
AL536_01510	COG0561	phosphatase activity
AL536_01520	COG0583	DNA-binding transcription factor activity
AL536_01530	COG3437	response regulator, receiver
AL536_01530	COG0784	Response regulator, receiver
AL536_01540	COG0113	porphobilinogen synthase activity
AL536_01545	COG0459	protein refolding
AL536_01550	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL536_01555	COG2239	Acts as a magnesium transporter
AL536_01575	COG2113	Glycine betaine
AL536_01580	COG4176	ABC-type proline glycine betaine transport system permease component
AL536_01585	COG4175	Glycine betaine
AL536_01595	COG1166	arginine decarboxylase activity
AL536_01605	COG1522	sequence-specific DNA binding
AL536_01620	COG0765	amino acid transport
AL536_01630	COG1686	Belongs to the peptidase S11 family
AL536_01645	COG1566	PFAM secretion protein HlyD family protein
AL536_01655	COG3338	carbonate dehydratase activity
AL536_01690	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL536_01700	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL536_01710	COG1280	lysine exporter protein (LysE YggA)
AL536_01715	COG0513	Belongs to the DEAD box helicase family
AL536_01730	COG0840	transmembrane signaling receptor activity
AL536_01745	COG2985	domain, Protein
AL536_01755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL536_01775	COG1280	lysine exporter protein (LysE YggA)
AL536_01820	COG3122	Protein conserved in bacteria
AL536_01840	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL536_01840	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL536_01845	COG0509	glycine decarboxylation via glycine cleavage system
AL536_01860	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL536_01870	COG3706	GGDEF domain
AL536_01875	COG5001	Diguanylate cyclase
AL536_01880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL536_01895	COG0546	phosphoglycolate phosphatase activity
AL536_01915	COG0484	heat shock protein binding
AL536_01925	COG1716	ATPase activity
AL536_01925	COG5001	Diguanylate cyclase
AL536_01930	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL536_01940	COG4181	ATPase activity
AL536_01945	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL536_01955	COG1984	allophanate hydrolase subunit 2
AL536_01965	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AL536_01970	COG5001	Diguanylate cyclase
AL536_01970	COG3447	MASE1 domain protein
AL536_01970	COG5002	protein histidine kinase activity
AL536_01975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL536_01980	COG0840	transmembrane signaling receptor activity
AL536_01985	COG0814	amino acid
AL536_01990	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AL536_01995	COG0513	Belongs to the DEAD box helicase family
AL536_02000	COG1309	transcriptional regulator
AL536_02010	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL536_02030	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL536_02060	COG0840	transmembrane signaling receptor activity
AL536_02070	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL536_02080	COG0463	Glycosyl transferase, family 2
AL536_02090	COG0583	DNA-binding transcription factor activity
AL536_02095	COG0697	spore germination
AL536_02100	COG1917	Cupin 2, conserved barrel domain protein
AL536_02100	COG2207	Transcriptional regulator
AL536_02125	COG0330	HflC and HflK could
AL536_02135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL536_02145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL536_02150	COG0583	DNA-binding transcription factor activity
AL536_02155	COG3781	membrane
AL536_02165	COG1271	oxidase subunit
AL536_02170	COG1294	oxidase, subunit
AL536_02175	COG0800	Aldolase
AL536_02180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL536_02185	COG1904	glucuronate isomerase
AL536_02190	COG0246	Mannitol dehydrogenase
AL536_02205	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL536_02215	COG2186	Transcriptional regulator
AL536_02225	COG2390	Transcriptional regulator
AL536_02235	COG1070	Carbohydrate kinase
AL536_02245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL536_02260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL536_02290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL536_02325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL536_02330	COG2146	nitrite reductase [NAD(P)H] activity
AL536_02335	COG2116	formate transmembrane transporter activity
AL536_02365	COG2814	Major facilitator Superfamily
AL536_02370	COG3118	belongs to the thioredoxin family
AL536_02375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL536_02390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL536_02400	COG1596	polysaccharide export
AL536_02425	COG0438	transferase activity, transferring glycosyl groups
AL536_02430	COG0438	transferase activity, transferring glycosyl groups
AL536_02430	COG0297	glycogen (starch) synthase activity
AL536_02445	COG0247	lactate metabolic process
AL536_02450	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
AL536_02455	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL536_02460	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL536_02465	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AL536_02510	COG4386	tail sheath protein
AL536_02550	COG4695	Portal protein
AL536_02710	COG4974	Belongs to the 'phage' integrase family
AL536_02730	COG2827	Endonuclease containing a URI domain
AL536_02740	COG1879	ABC-type sugar transport system periplasmic component
AL536_02745	COG5002	protein histidine kinase activity
AL536_02745	COG0784	Response regulator, receiver
AL536_02765	COG1492	cobalamin metabolic process
AL536_02770	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL536_02775	COG4149	molybdate abc transporter
AL536_02780	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL536_02795	COG1289	transmembrane transporter activity
AL536_02835	COG0210	DNA helicase
AL536_02840	COG1335	isochorismatase
AL536_02845	COG1803	Methylglyoxal synthase
AL536_02850	COG1879	ABC-type sugar transport system periplasmic component
AL536_02855	COG0784	Response regulator, receiver
AL536_02855	COG2198	Histidine kinase
AL536_02855	COG2205	protein histidine kinase activity
AL536_02860	COG0469	pyruvate kinase activity
AL536_02865	COG2271	Major facilitator Superfamily
AL536_02870	COG1840	ABC-type Fe3 transport system, periplasmic component
AL536_02890	COG1979	alcohol dehydrogenase
AL536_02895	COG2207	Transcriptional regulator
AL536_02910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL536_02915	COG3706	GGDEF domain
AL536_02935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL536_02940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL536_02950	COG0183	Belongs to the thiolase family
AL536_02985	COG0243	molybdopterin cofactor binding
AL536_03000	COG3850	Histidine kinase
AL536_03005	COG2197	response regulator
AL536_03010	COG3069	C4-dicarboxylate transmembrane transporter activity
AL536_03025	COG2814	Major facilitator Superfamily
AL536_03030	COG0840	transmembrane signaling receptor activity
AL536_03035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL536_03040	COG0545	Peptidyl-prolyl cis-trans isomerase
AL536_03055	COG0840	transmembrane signaling receptor activity
AL536_03060	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL536_03075	COG2897	thiosulfate sulfurtransferase activity
AL536_03080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL536_03090	COG0302	gtp cyclohydrolase
AL536_03095	COG0531	amino acid
AL536_03105	COG4303	Ethanolamine ammonia lyase large subunit
AL536_03110	COG2207	Transcriptional regulator
AL536_03115	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL536_03115	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL536_03120	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AL536_03125	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL536_03135	COG1011	Hydrolase
AL536_03140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL536_03150	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL536_03160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL536_03170	COG3842	ATPase activity
AL536_03190	COG2866	Carboxypeptidase
AL536_03215	COG4166	transmembrane transport
AL536_03220	COG4174	ABC transporter (Permease)
AL536_03225	COG4239	(ABC) transporter, permease
AL536_03230	COG4172	Belongs to the ABC transporter superfamily
AL536_03235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL536_03250	COG2205	protein histidine kinase activity
AL536_03250	COG0784	Response regulator, receiver
AL536_03255	COG5001	Diguanylate cyclase
AL536_03255	COG4251	negative regulation of phosphorylation
AL536_03255	COG3706	GGDEF domain
AL536_03255	COG2203	Gaf domain
AL536_03265	COG3706	GGDEF domain
AL536_03280	COG2501	S4 domain
AL536_03320	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL536_03345	COG1979	alcohol dehydrogenase
AL536_03350	COG2207	Transcriptional regulator
AL536_03370	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL536_03380	COG0488	(ABC) transporter
AL536_03400	COG2814	Major facilitator Superfamily
AL536_03420	COG3710	Transcriptional regulator
AL536_03450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_03465	COG2233	PERMEase
AL536_03485	COG1953	Uracil, thiamine, allantoin
AL536_03495	COG0765	amino acid transport
AL536_03500	COG0765	amino acid transport
AL536_03530	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL536_03550	COG0402	S-adenosylhomocysteine deaminase activity
AL536_03555	COG2351	hydroxyisourate hydrolase activity
AL536_03595	COG1129	ABC transporter
AL536_03600	COG1309	transcriptional regulator
AL536_03610	COG3706	GGDEF domain
AL536_03620	COG3706	GGDEF domain
AL536_03620	COG0745	RESPONSE REGULATOR receiver
AL536_03635	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL536_03640	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL536_03650	COG0745	RESPONSE REGULATOR receiver
AL536_03665	COG0023	Translation Initiation Factor
AL536_03680	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL536_03690	COG0045	succinate-CoA ligase (ADP-forming) activity
AL536_03690	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL536_03690	COG1042	CoA-binding domain protein
AL536_03695	COG0583	DNA-binding transcription factor activity
AL536_03700	COG1629	transport
AL536_03700	COG4771	TonB-dependent receptor
AL536_03720	COG2050	protein possibly involved in aromatic compounds catabolism
AL536_03725	COG0501	Belongs to the peptidase M48B family
AL536_03730	COG2824	Alkylphosphonate utilization operon protein PhnA
AL536_03740	COG0861	Integral membrane protein TerC family
AL536_03745	COG0737	Belongs to the 5'-nucleotidase family
AL536_03750	COG3593	DNA synthesis involved in DNA repair
AL536_03760	COG0583	DNA-binding transcription factor activity
AL536_03765	COG2116	formate transmembrane transporter activity
AL536_03770	COG2353	YceI-like domain
AL536_03775	COG3038	cytochrome b561
AL536_03800	COG5001	Diguanylate cyclase
AL536_03810	COG0243	molybdopterin cofactor binding
AL536_03815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL536_03820	COG0543	2 iron, 2 sulfur cluster binding
AL536_03820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL536_03825	COG5002	protein histidine kinase activity
AL536_03825	COG2205	protein histidine kinase activity
AL536_03825	COG0784	Response regulator, receiver
AL536_03830	COG3437	response regulator, receiver
AL536_03840	COG2207	Transcriptional regulator
AL536_03845	COG0582	viral genome integration into host DNA
AL536_03855	COG2916	Histone family protein nucleoid-structuring protein H-NS
AL536_03860	COG2202	Pas domain
AL536_03860	COG2199	diguanylate cyclase activity
AL536_03860	COG2200	EAL domain
AL536_03875	COG2200	EAL domain
AL536_03920	COG2181	nitrate reductase activity
AL536_03925	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AL536_03930	COG1140	nitrate reductase beta subunit
AL536_03935	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AL536_03940	COG2223	nitrite transmembrane transporter activity
AL536_03945	COG3850	Histidine kinase
AL536_03950	COG2197	response regulator
AL536_03955	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AL536_03965	COG0840	transmembrane signaling receptor activity
AL536_03965	COG3290	protein histidine kinase activity
AL536_04015	COG1518	maintenance of DNA repeat elements
AL536_04030	COG1609	Transcriptional regulator
AL536_04040	COG2017	converts alpha-aldose to the beta-anomer
AL536_04045	COG3459	Glycosyltransferase 36 associated
AL536_04055	COG2723	6-phospho-beta-galactosidase activity
AL536_04060	COG0395	ABC-type sugar transport system, permease component
AL536_04065	COG1175	transmembrane transport
AL536_04075	COG1609	Transcriptional regulator
AL536_04080	COG0840	transmembrane signaling receptor activity
AL536_04090	COG0534	Mate efflux family protein
AL536_04105	COG2003	Belongs to the UPF0758 family
AL536_04140	COG0328	RNA-DNA hybrid ribonuclease activity
AL536_04200	COG0523	cobalamin synthesis protein
AL536_04205	COG0038	chloride channel
AL536_04215	COG0156	8-amino-7-oxononanoate synthase activity
AL536_04220	COG2205	protein histidine kinase activity
AL536_04220	COG0784	Response regulator, receiver
AL536_04225	COG0419	ATPase involved in DNA repair
AL536_04235	COG1609	Transcriptional regulator
AL536_04240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_04240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_04245	COG1105	Belongs to the carbohydrate kinase PfkB family
AL536_04250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_04250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_04250	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL536_04255	COG0189	ligase activity
AL536_04255	COG4067	protein conserved in archaea
AL536_04265	COG0602	queuosine metabolic process
AL536_04270	COG1328	CTP reductase activity
AL536_04335	COG1280	lysine exporter protein (LysE YggA)
AL536_04340	COG0745	RESPONSE REGULATOR receiver
AL536_04350	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL536_04360	COG0583	DNA-binding transcription factor activity
AL536_04375	COG1309	transcriptional regulator
AL536_04380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL536_04410	COG1335	isochorismatase
AL536_04415	COG4977	sequence-specific DNA binding
AL536_04420	COG0456	acetyltransferase
AL536_04430	COG1280	lysine exporter protein (LysE YggA)
AL536_04435	COG0494	nUDIX hydrolase
AL536_04445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL536_04475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL536_04495	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_04505	COG0454	-acetyltransferase
AL536_04565	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL536_04570	COG0789	Transcriptional regulator
AL536_04620	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_04665	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL536_04670	COG0513	Belongs to the DEAD box helicase family
AL536_04675	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AL536_04685	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL536_04695	COG0583	DNA-binding transcription factor activity
AL536_04710	COG3710	Transcriptional regulator
AL536_04715	COG4232	protein-disulfide reductase activity
AL536_04720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL536_04725	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL536_04735	COG1252	NADH dehydrogenase
AL536_04745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_04750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_04760	COG2207	Transcriptional regulator
AL536_04765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_04765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_04765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_04775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_04790	COG2015	COG2015, Alkyl sulfatase and related hydrolases
AL536_04800	COG1349	DNA-binding transcription factor activity
AL536_04805	COG0110	maltose O-acetyltransferase activity
AL536_04810	COG3706	GGDEF domain
AL536_04820	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AL536_04830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL536_04850	COG0747	negative chemotaxis
AL536_04855	COG4172	Belongs to the ABC transporter superfamily
AL536_04865	COG3437	response regulator, receiver
AL536_04870	COG0784	Response regulator, receiver
AL536_04870	COG2198	Histidine kinase
AL536_04870	COG2205	protein histidine kinase activity
AL536_04880	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL536_04905	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL536_04920	COG2423	ornithine cyclodeaminase activity
AL536_04930	COG4145	pantothenate transmembrane transporter activity
AL536_04935	COG0583	DNA-binding transcription factor activity
AL536_04940	COG0435	Glutathione S-transferase
AL536_04945	COG0400	carboxylic ester hydrolase activity
AL536_04950	COG1280	lysine exporter protein (LysE YggA)
AL536_04965	COG1473	amidohydrolase
AL536_04985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_04990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL536_04995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL536_05005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL536_05020	COG2721	sulfolactate sulfo-lyase activity
AL536_05075	COG0625	glutathione transferase activity
AL536_05090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL536_05100	COG0573	inorganic phosphate transmembrane transporter activity
AL536_05105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL536_05125	COG1464	Belongs to the NlpA lipoprotein family
AL536_05130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL536_05130	COG0512	Glutamine amidotransferase of anthranilate synthase
AL536_05150	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL536_05165	COG0653	protein targeting
AL536_05170	COG2814	Major facilitator Superfamily
AL536_05180	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_05190	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_05200	COG1024	Enoyl-CoA hydratase
AL536_05205	COG1024	Enoyl-CoA hydratase
AL536_05210	COG1960	acyl-CoA dehydrogenase activity
AL536_05220	COG0183	Belongs to the thiolase family
AL536_05230	COG1960	acyl-CoA dehydrogenase activity
AL536_05235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL536_05240	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL536_05255	COG0450	alkyl hydroperoxide reductase
AL536_05260	COG3634	alkyl hydroperoxide reductase activity
AL536_05290	COG2207	Transcriptional regulator
AL536_05290	COG1609	Transcriptional regulator
AL536_05295	COG1454	alcohol dehydrogenase
AL536_05300	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL536_05340	COG1051	belongs to the nudix hydrolase family
AL536_05345	COG0784	Response regulator, receiver
AL536_05345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL536_05385	COG0582	viral genome integration into host DNA
AL536_05400	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL536_05415	COG1609	Transcriptional regulator
AL536_05415	COG2207	Transcriptional regulator
AL536_05420	COG4604	ABC transporter, ATP-binding protein
AL536_05425	COG4605	iron ion homeostasis
AL536_05430	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_05450	COG3291	Pkd domain containing protein
AL536_05450	COG4412	M6 family metalloprotease domain protein
AL536_05455	COG5380	lipid catabolic process
AL536_05460	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AL536_05470	COG1522	sequence-specific DNA binding
AL536_05490	COG2814	Major facilitator Superfamily
AL536_05500	COG0840	transmembrane signaling receptor activity
AL536_05520	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL536_05525	COG3279	Response regulator of the LytR AlgR family
AL536_05530	COG3275	phosphorelay sensor kinase activity
AL536_05535	COG4989	oxidoreductase activity
AL536_05550	COG0366	Alpha amylase catalytic
AL536_05555	COG3227	Zinc metalloprotease (Elastase)
AL536_05560	COG3047	cAMP biosynthetic process
AL536_05565	COG0071	Belongs to the small heat shock protein (HSP20) family
AL536_05580	COG0251	oxidation-reduction process
AL536_05625	COG1132	(ABC) transporter
AL536_05630	COG1132	(ABC) transporter
AL536_05640	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL536_05645	COG2246	polysaccharide biosynthetic process
AL536_05660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL536_05670	COG0242	peptide deformylase activity
AL536_05680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_05685	COG2084	Dehydrogenase
AL536_05695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL536_05700	COG0583	DNA-binding transcription factor activity
AL536_05750	COG1063	alcohol dehydrogenase
AL536_05755	COG0156	8-amino-7-oxononanoate synthase activity
AL536_05760	COG1012	belongs to the aldehyde dehydrogenase family
AL536_05765	COG3284	Transcriptional regulator
AL536_05775	COG0346	lactoylglutathione lyase activity
AL536_05795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL536_05805	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL536_05810	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL536_05815	COG0363	glucosamine-6-phosphate deaminase activity
AL536_05820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL536_05835	COG0583	DNA-binding transcription factor activity
AL536_05850	COG0646	methionine synthase
AL536_05850	COG1410	methionine synthase
AL536_05855	COG0531	amino acid
AL536_05870	COG1473	amidohydrolase
AL536_05875	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL536_05880	COG1929	Belongs to the glycerate kinase type-1 family
AL536_05885	COG2610	gluconate transmembrane transporter activity
AL536_05890	COG3835	regulator
AL536_05895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL536_05900	COG4533	DNA binding
AL536_05915	COG0840	transmembrane signaling receptor activity
AL536_05970	COG4964	Belongs to the GSP D family
AL536_06010	COG0798	PFAM Bile acid sodium symporter
AL536_06035	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL536_06040	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL536_06045	COG1129	ABC transporter
AL536_06070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_06075	COG4974	Belongs to the 'phage' integrase family
AL536_06080	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AL536_06095	COG1482	cell wall glycoprotein biosynthetic process
AL536_06100	COG0840	transmembrane signaling receptor activity
AL536_06105	COG4580	involved in the transport of maltose and maltodextrins
AL536_06110	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AL536_06115	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
AL536_06125	COG1609	Transcriptional regulator
AL536_06135	COG2942	2-epimerase
AL536_06140	COG5578	integral membrane protein
AL536_06145	COG0395	ABC-type sugar transport system, permease component
AL536_06150	COG1175	transmembrane transport
AL536_06270	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL536_06275	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL536_06275	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL536_06285	COG0745	RESPONSE REGULATOR receiver
AL536_06305	COG3036	rescue of stalled ribosome
AL536_06310	COG1278	Cold shock
AL536_06315	COG4681	YaeQ
AL536_06320	COG3706	GGDEF domain
AL536_06325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL536_06325	COG1017	nitric oxide dioxygenase activity
AL536_06330	COG3604	Transcriptional regulator
AL536_06340	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL536_06345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL536_06355	COG0366	Alpha amylase catalytic
AL536_06375	COG0714	Associated with various cellular activities
AL536_06395	COG2304	oxidoreductase activity
AL536_06410	COG3706	GGDEF domain
AL536_06420	COG5002	protein histidine kinase activity
AL536_06420	COG2205	protein histidine kinase activity
AL536_06420	COG0784	Response regulator, receiver
AL536_06425	COG0745	RESPONSE REGULATOR receiver
AL536_06425	COG3706	GGDEF domain
AL536_06435	COG3724	N-succinylarginine dihydrolase activity
AL536_06440	COG1012	belongs to the aldehyde dehydrogenase family
AL536_06465	COG4948	Mandelate Racemase Muconate Lactonizing
AL536_06490	COG0583	DNA-binding transcription factor activity
AL536_06515	COG3171	Protein conserved in bacteria
AL536_06520	COG0589	response to stress
AL536_06530	COG3530	Putative quorum-sensing-regulated virulence factor
AL536_06540	COG0579	oxidoreductase
AL536_06555	COG2204	response regulator
AL536_06565	COG1929	Belongs to the glycerate kinase type-1 family
AL536_06570	COG0383	alpha-mannosidase activity
AL536_06575	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_06575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_06575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL536_06580	COG2188	Transcriptional regulator
AL536_06605	COG5001	Diguanylate cyclase
AL536_06605	COG3300	MHYT domain
AL536_06610	COG2271	Major facilitator Superfamily
AL536_06615	COG0584	glycerophosphoryl diester phosphodiesterase
AL536_06620	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AL536_06625	COG0583	DNA-binding transcription factor activity
AL536_06635	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL536_06640	COG1879	ABC-type sugar transport system periplasmic component
AL536_06645	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL536_06650	COG1129	ABC transporter
AL536_06655	COG1869	D-ribose catabolic process
AL536_06765	COG1280	lysine exporter protein (LysE YggA)
AL536_06770	COG1846	Transcriptional regulator
AL536_06785	COG0564	pseudouridine synthase activity
AL536_06790	COG1309	transcriptional regulator
AL536_06795	COG2130	NADP-dependent
AL536_06810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL536_06840	COG3842	ATPase activity
AL536_06850	COG2200	EAL domain
AL536_06855	COG0656	L-ascorbic acid biosynthetic process
AL536_06860	COG1902	pentaerythritol trinitrate reductase activity
AL536_06865	COG0583	DNA-binding transcription factor activity
AL536_06870	COG2814	Major facilitator Superfamily
AL536_06890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL536_06905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL536_06915	COG4702	Belongs to the UPF0303 family
AL536_06920	COG0673	inositol 2-dehydrogenase activity
AL536_06925	COG1349	DNA-binding transcription factor activity
AL536_06930	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL536_06950	COG3240	lipase activity
AL536_06955	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_06960	COG0583	DNA-binding transcription factor activity
AL536_06970	COG1120	ATPase activity
AL536_06975	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_06980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_06985	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL536_06990	COG4774	siderophore transport
AL536_07015	COG0840	transmembrane signaling receptor activity
AL536_07020	COG3384	dioxygenase
AL536_07025	COG0583	DNA-binding transcription factor activity
AL536_07035	COG1342	Belongs to the UPF0251 family
AL536_07040	COG0778	Nitroreductase
AL536_07045	COG0583	DNA-binding transcription factor activity
AL536_07055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL536_07060	COG0697	spore germination
AL536_07075	COG2814	Major facilitator Superfamily
AL536_07080	COG0583	DNA-binding transcription factor activity
AL536_07085	COG3300	MHYT domain
AL536_07085	COG5001	Diguanylate cyclase
AL536_07090	COG0739	heme binding
AL536_07105	COG0659	secondary active sulfate transmembrane transporter activity
AL536_07120	COG2199	diguanylate cyclase activity
AL536_07130	COG0581	inorganic phosphate transmembrane transporter activity
AL536_07135	COG0573	inorganic phosphate transmembrane transporter activity
AL536_07140	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL536_07145	COG0840	transmembrane signaling receptor activity
AL536_07150	COG0513	Belongs to the DEAD box helicase family
AL536_07160	COG1376	ErfK ybiS ycfS ynhG family protein
AL536_07160	COG1388	LysM domain
AL536_07165	COG0415	Belongs to the DNA photolyase family
AL536_07175	COG3272	Protein of unknown function (DUF1722)
AL536_07180	COG0813	purine-nucleoside phosphorylase activity
AL536_07195	COG3706	GGDEF domain
AL536_07205	COG1566	PFAM secretion protein HlyD family protein
AL536_07240	COG0786	glutamate:sodium symporter activity
AL536_07255	COG1999	signal sequence binding
AL536_07265	COG1162	GTPase activity
AL536_07270	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL536_07285	COG4580	involved in the transport of maltose and maltodextrins
AL536_07305	COG1132	(ABC) transporter
AL536_07315	COG0671	phosphoesterase, PA-phosphatase related
AL536_07325	COG3383	formate dehydrogenase (NAD+) activity
AL536_07330	COG0010	Belongs to the arginase family
AL536_07340	COG0840	transmembrane signaling receptor activity
AL536_07350	COG1131	(ABC) transporter
AL536_07355	COG2188	Transcriptional regulator
AL536_07365	COG3033	Beta-eliminating lyase
AL536_07370	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL536_07375	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL536_07385	COG0471	metal ion transport
AL536_07410	COG3788	relative of glutathione S-transferase, MAPEG superfamily
AL536_07430	COG3501	Rhs element vgr protein
AL536_07440	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL536_07445	COG1640	4-alpha-glucanotransferase
AL536_07450	COG0058	SHG alpha-glucan phosphorylase activity
AL536_07455	COG2909	trisaccharide binding
AL536_07470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL536_07475	COG1845	cytochrome c oxidase, subunit III
AL536_07480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL536_07485	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL536_07500	COG2084	Dehydrogenase
AL536_07515	COG0217	transcriptional regulatory protein
AL536_07550	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL536_07555	COG1444	tRNA N-acetyltransferase activity
AL536_07565	COG0745	RESPONSE REGULATOR receiver
AL536_07570	COG2198	Histidine kinase
AL536_07570	COG0643	Histidine kinase
AL536_07575	COG0835	chemotaxis
AL536_07580	COG0835	chemotaxis
AL536_07585	COG0840	transmembrane signaling receptor activity
AL536_07590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL536_07600	COG2201	protein-glutamate methylesterase activity
AL536_07615	COG0745	RESPONSE REGULATOR receiver
AL536_07645	COG0259	pyridoxamine-phosphate oxidase activity
AL536_07655	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL536_07670	COG0204	Acyl-transferase
AL536_07675	COG0251	oxidation-reduction process
AL536_07680	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AL536_07685	COG0540	Belongs to the ATCase OTCase family
AL536_07690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL536_07695	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL536_07700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL536_07710	COG0564	pseudouridine synthase activity
AL536_07715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL536_07720	COG0525	valine-tRNA ligase activity
AL536_07735	COG0795	lipopolysaccharide-transporting ATPase activity
AL536_07740	COG0795	lipopolysaccharide-transporting ATPase activity
AL536_07755	COG3706	GGDEF domain
AL536_07780	COG2199	diguanylate cyclase activity
AL536_07780	COG2200	EAL domain
AL536_07780	COG2203	Gaf domain
AL536_07790	COG3437	response regulator, receiver
AL536_07840	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AL536_07845	COG0473	3-isopropylmalate dehydrogenase activity
AL536_07850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL536_07870	COG0583	DNA-binding transcription factor activity
AL536_07875	COG1022	Amp-dependent synthetase and ligase
AL536_07880	COG0028	Belongs to the TPP enzyme family
AL536_07885	COG0440	acetolactate synthase activity
AL536_07890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL536_07900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL536_07910	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AL536_07920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL536_07925	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL536_07940	COG0354	folic acid binding
AL536_07945	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL536_07955	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL536_07960	COG1595	DNA-templated transcription, initiation
AL536_07975	COG3086	response to oxidative stress
AL536_07980	COG0481	GTPase activity
AL536_07985	COG0681	Belongs to the peptidase S26 family
AL536_07990	COG0571	ribonuclease III activity
AL536_07995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL536_08000	COG1381	Involved in DNA repair and RecF pathway recombination
AL536_08005	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL536_08010	COG0736	holo-[acyl-carrier-protein] synthase activity
AL536_08020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL536_08025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL536_08030	COG3956	TIGRFAM MazG family protein
AL536_08035	COG0504	CTP synthase activity
AL536_08040	COG0148	phosphopyruvate hydratase activity
AL536_08045	COG0617	tRNA 3'-terminal CCA addition
AL536_08050	COG3409	Peptidoglycan-binding domain 1 protein
AL536_08050	COG3267	Type II secretory pathway component ExeA
AL536_08060	COG4991	sh3 domain protein
AL536_08065	COG0306	phosphate transporter
AL536_08070	COG1392	Phosphate transport regulator
AL536_08075	COG3025	triphosphatase activity
AL536_08080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL536_08090	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL536_08095	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL536_08095	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL536_08100	COG1538	Outer membrane efflux protein
AL536_08105	COG0494	nUDIX hydrolase
AL536_08110	COG3151	Protein conserved in bacteria
AL536_08120	COG3150	esterase
AL536_08125	COG0187	DNA topoisomerase II activity
AL536_08130	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AL536_08135	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AL536_08140	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL536_08155	COG1459	type II secretion system
AL536_08160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL536_08180	COG0716	FMN binding
AL536_08185	COG4974	Belongs to the 'phage' integrase family
AL536_08190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL536_08195	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL536_08200	COG2186	Transcriptional regulator
AL536_08205	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL536_08210	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL536_08215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL536_08230	COG0288	reversible hydration of carbon dioxide
AL536_08235	COG1131	(ABC) transporter
AL536_08240	COG0842	Transport permease protein
AL536_08245	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL536_08250	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL536_08255	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL536_08265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL536_08270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL536_08275	COG1489	DNA binding
AL536_08280	COG1643	Atp-dependent helicase
AL536_08285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL536_08290	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL536_08295	COG1049	propionate catabolic process, 2-methylcitrate cycle
AL536_08300	COG3112	Uncharacterised protein family (UPF0231)
AL536_08305	COG0347	Belongs to the P(II) protein family
AL536_08310	COG0004	ammonium transporteR
AL536_08315	COG1840	ABC-type Fe3 transport system, periplasmic component
AL536_08325	COG3842	ATPase activity
AL536_08330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL536_08345	COG2971	BadF BadG BcrA BcrD
AL536_08355	COG4608	Belongs to the ABC transporter superfamily
AL536_08360	COG0444	Belongs to the ABC transporter superfamily
AL536_08365	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL536_08375	COG0747	negative chemotaxis
AL536_08390	COG0628	permease
AL536_08395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL536_08400	COG0316	Belongs to the HesB IscA family
AL536_08415	COG0739	heme binding
AL536_08420	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL536_08430	COG2239	Acts as a magnesium transporter
AL536_08435	COG2027	D-alanyl-D-alanine carboxypeptidase
AL536_08440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL536_08445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL536_08450	COG1534	Rna-binding protein
AL536_08460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL536_08465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL536_08470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL536_08475	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL536_08490	COG0779	Required for maturation of 30S ribosomal subunits
AL536_08495	COG0195	Participates in both transcription termination and antitermination
AL536_08505	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL536_08510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL536_08535	COG0534	Mate efflux family protein
AL536_08560	COG3153	acetyltransferase
AL536_08580	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL536_08585	COG0513	Belongs to the DEAD box helicase family
AL536_08610	COG2204	response regulator
AL536_08620	COG0667	Aldo Keto reductase
AL536_08630	COG3066	DNA modification
AL536_08635	COG0494	nUDIX hydrolase
AL536_08645	COG0730	response to heat
AL536_08655	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL536_08660	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL536_08665	COG0583	DNA-binding transcription factor activity
AL536_08670	COG0640	Transcriptional regulator
AL536_08680	COG0728	peptidoglycan biosynthetic process
AL536_08685	COG0196	riboflavin kinase activity
AL536_08690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL536_08695	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL536_08700	COG1047	Peptidyl-prolyl cis-trans
AL536_08705	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL536_08710	COG1966	Carbon starvation protein
AL536_08725	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL536_08730	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL536_08740	COG3279	Response regulator of the LytR AlgR family
AL536_08745	COG3275	phosphorelay sensor kinase activity
AL536_08750	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL536_08755	COG1605	Chorismate mutase
AL536_08755	COG0287	Prephenate dehydrogenase
AL536_08765	COG0488	(ABC) transporter
AL536_08780	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AL536_08785	COG5001	Diguanylate cyclase
AL536_08790	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL536_08795	COG1605	Chorismate mutase
AL536_08795	COG0077	Prephenate dehydratase
AL536_08800	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL536_08805	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL536_08810	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL536_08815	COG0564	pseudouridine synthase activity
AL536_08825	COG0542	response to heat
AL536_08835	COG0590	tRNA wobble adenosine to inosine editing
AL536_08840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL536_08845	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AL536_08925	COG0271	Belongs to the BolA IbaG family
AL536_08930	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL536_08935	COG1805	sodium ion transport
AL536_08945	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL536_08950	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL536_08955	COG2871	sodium ion transport
AL536_08960	COG1477	protein flavinylation
AL536_08975	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL536_08985	COG5001	Diguanylate cyclase
AL536_08985	COG4251	negative regulation of phosphorylation
AL536_08985	COG3706	GGDEF domain
AL536_08985	COG2203	Gaf domain
AL536_08990	COG0733	neurotransmitter:sodium symporter activity
AL536_09000	COG0189	ligase activity
AL536_09005	COG0189	ligase activity
AL536_09005	COG4067	protein conserved in archaea
AL536_09010	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL536_09015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_09020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL536_09030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL536_09040	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL536_09045	COG2252	PERMEase
AL536_09050	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL536_09065	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL536_09070	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL536_09075	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL536_09080	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL536_09080	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL536_09100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL536_09105	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL536_09110	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL536_09120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AL536_09125	COG0024	Methionine aminopeptidase
AL536_09150	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL536_09155	COG0575	Belongs to the CDS family
AL536_09160	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL536_09165	COG0750	zinc metalloprotease
AL536_09175	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL536_09180	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL536_09185	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL536_09205	COG0587	DNA-directed DNA polymerase activity
AL536_09210	COG0825	malonyl-CoA metabolic process
AL536_09215	COG0037	tRNA processing
AL536_09225	COG0347	Belongs to the P(II) protein family
AL536_09240	COG1388	LysM domain
AL536_09240	COG0741	lytic transglycosylase activity
AL536_09250	COG2226	methyltransferase
AL536_09255	COG0328	RNA-DNA hybrid ribonuclease activity
AL536_09260	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL536_09270	COG1960	acyl-CoA dehydrogenase activity
AL536_09275	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL536_09280	COG0121	glutamine amidotransferase
AL536_09285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL536_09290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL536_09295	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL536_09300	COG1187	pseudouridine synthase activity
AL536_09305	COG2840	Smr protein MutS2
AL536_09330	COG2217	Heavy metal translocating P-type atpase
AL536_09330	COG2608	mercury ion transmembrane transporter activity
AL536_09335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL536_09355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL536_09360	COG2194	sulfuric ester hydrolase activity
AL536_09395	COG2747	anti-sigma28 factor FlgM
AL536_09405	COG0784	Response regulator, receiver
AL536_09405	COG0835	chemotaxis
AL536_09410	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL536_09415	COG1815	bacterial-type flagellum-dependent cell motility
AL536_09420	COG1558	bacterial-type flagellum-dependent cell motility
AL536_09425	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL536_09430	COG1749	Flagellar hook protein flgE
AL536_09435	COG4787	bacterial-type flagellum-dependent cell motility
AL536_09440	COG4786	Flagellar basal body rod
AL536_09445	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL536_09450	COG1706	bacterial-type flagellum-dependent cell motility
AL536_09455	COG3951	Flagellar rod assembly protein muramidase FlgJ
AL536_09455	COG1705	Flagellar rod assembly protein muramidase FlgJ
AL536_09470	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL536_09570	COG0193	aminoacyl-tRNA hydrolase activity
AL536_09575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL536_09585	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AL536_09590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL536_09595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL536_09600	COG2890	protein-(glutamine-N5) methyltransferase activity
AL536_09605	COG3094	Invasion gene expression up-regulator, SirB
AL536_09610	COG2912	Transglutaminase-like superfamily
AL536_09620	COG0737	Belongs to the 5'-nucleotidase family
AL536_09630	COG2233	PERMEase
AL536_09650	COG1393	Belongs to the ArsC family
AL536_09655	COG4783	chaperone-mediated protein folding
AL536_09675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL536_09680	COG2716	regulation of RNA biosynthetic process
AL536_09685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL536_09690	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL536_09700	COG1876	peptidase activity
AL536_09705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL536_09710	COG1393	Belongs to the ArsC family
AL536_09720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL536_09730	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AL536_09750	COG2837	iron assimilation
AL536_09760	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL536_09765	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL536_09770	COG1334	flagellar protein FlaG
AL536_09775	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL536_09785	COG1516	flagellar protein fliS
AL536_09790	COG2204	response regulator
AL536_09795	COG4191	Histidine kinase
AL536_09800	COG2204	response regulator
AL536_09805	COG1677	Flagellar hook-basal body complex protein FliE
AL536_09815	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL536_09865	COG1987	bacterial-type flagellum assembly
AL536_09885	COG2890	protein-(glutamine-N5) methyltransferase activity
AL536_09890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL536_09895	COG0583	DNA-binding transcription factor activity
AL536_09900	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_09905	COG2860	membrane
AL536_09910	COG3101	peptidyl-lysine hydroxylation
AL536_09930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL536_09935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL536_09940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL536_09945	COG0735	belongs to the Fur family
AL536_09955	COG0583	DNA-binding transcription factor activity
AL536_09960	COG1380	Effector of murein hydrolase LrgA
AL536_09965	COG1346	cytolysis
AL536_09980	COG0596	Alpha beta hydrolase
AL536_09985	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
AL536_09990	COG0033	Phosphoglucomutase
AL536_10000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL536_10010	COG2009	succinate dehydrogenase
AL536_10015	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL536_10030	COG0567	Dehydrogenase, E1 component
AL536_10035	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL536_10050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL536_10055	COG1121	(ABC) transporter
AL536_10060	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL536_10070	COG1918	ferrous iron import across plasma membrane
AL536_10090	COG0018	arginyl-trna synthetase
AL536_10095	COG3102	Protein conserved in bacteria
AL536_10105	COG2062	phosphohistidine phosphatase, SixA
AL536_10120	COG0455	bacterial-type flagellum organization
AL536_10135	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL536_10140	COG2198	Histidine kinase
AL536_10140	COG0643	Histidine kinase
AL536_10145	COG2201	protein-glutamate methylesterase activity
AL536_10150	COG1192	Involved in chromosome partitioning
AL536_10160	COG0835	chemotaxis
AL536_10170	COG4133	protoheme IX ABC transporter activity
AL536_10175	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL536_10180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL536_10185	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL536_10190	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
AL536_10195	COG1138	Cytochrome C-type biogenesis protein
AL536_10200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL536_10215	COG2853	Lipoprotein
AL536_10235	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL536_10240	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL536_10245	COG3384	dioxygenase
AL536_10270	COG0667	Aldo Keto reductase
AL536_10285	COG0583	DNA-binding transcription factor activity
AL536_10290	COG2159	amidohydrolase
AL536_10295	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL536_10335	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL536_10350	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL536_10360	COG1448	Aminotransferase
AL536_10380	COG3083	sulfuric ester hydrolase activity
AL536_10390	COG3081	Nucleoid-associated protein
AL536_10400	COG1757	Na H antiporter
AL536_10405	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL536_10410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL536_10415	COG2095	MarC family integral membrane protein
AL536_10420	COG1454	alcohol dehydrogenase
AL536_10420	COG1012	belongs to the aldehyde dehydrogenase family
AL536_10430	COG0659	secondary active sulfate transmembrane transporter activity
AL536_10440	COG1530	ribonuclease E activity
AL536_10445	COG0564	pseudouridine synthase activity
AL536_10450	COG0424	maF-like protein
AL536_10455	COG1399	metal-binding, possibly nucleic acid-binding protein
AL536_10465	COG0416	fatty acid biosynthetic process
AL536_10470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL536_10490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL536_10495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL536_10500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL536_10505	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AL536_10510	COG0470	DNA polymerase III
AL536_10515	COG0084	hydrolase, TatD family'
AL536_10520	COG1263	PTS System
AL536_10520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL536_10520	COG2190	(PTS) system
AL536_10530	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL536_10530	COG1263	PTS System
AL536_10540	COG0733	neurotransmitter:sodium symporter activity
AL536_10550	COG4667	esterase of the alpha-beta hydrolase superfamily
AL536_10555	COG0469	pyruvate kinase activity
AL536_10560	COG1940	carbohydrate kinase activity
AL536_10565	COG0835	chemotaxis
AL536_10565	COG0784	Response regulator, receiver
AL536_10570	COG0587	DNA-directed DNA polymerase activity
AL536_10585	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_10590	COG0616	signal peptide processing
AL536_10640	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL536_10645	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AL536_10650	COG0436	Aminotransferase
AL536_10655	COG1169	isochorismate synthase
AL536_10660	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AL536_10665	COG0596	Alpha beta hydrolase
AL536_10670	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL536_10675	COG1441	menaquinone biosynthetic process
AL536_10690	COG2855	membrane
AL536_10695	COG0477	Major facilitator Superfamily
AL536_10715	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL536_10720	COG1388	LysM domain
AL536_10720	COG0741	lytic transglycosylase activity
AL536_10740	COG1815	bacterial-type flagellum-dependent cell motility
AL536_10745	COG1558	bacterial-type flagellum-dependent cell motility
AL536_10750	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL536_10755	COG1749	Flagellar hook protein flgE
AL536_10765	COG4786	Flagellar basal body rod
AL536_10770	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL536_10775	COG1706	bacterial-type flagellum-dependent cell motility
AL536_10785	COG1256	bacterial-type flagellum assembly
AL536_10785	COG4786	Flagellar basal body rod
AL536_10830	COG0702	epimerase
AL536_10835	COG3015	lipoprotein NlpE involved in copper resistance
AL536_10845	COG1360	Flagellar Motor Protein
AL536_10850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL536_10855	COG1191	sigma factor activity
AL536_10860	COG1580	Controls the rotational direction of flagella during chemotaxis
AL536_10880	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL536_10885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL536_10900	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL536_10910	COG1987	bacterial-type flagellum assembly
AL536_10930	COG3047	cAMP biosynthetic process
AL536_10930	COG2885	chlorophyll binding
AL536_10935	COG2204	response regulator
AL536_10950	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL536_10975	COG1522	sequence-specific DNA binding
AL536_10980	COG1946	Acyl-CoA thioesterase
AL536_10985	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL536_11000	COG2203	Gaf domain
AL536_11000	COG2199	diguanylate cyclase activity
AL536_11110	COG2203	Gaf domain
AL536_11110	COG3706	GGDEF domain
AL536_11110	COG4251	negative regulation of phosphorylation
AL536_11110	COG5001	Diguanylate cyclase
AL536_11160	COG0431	NADPH-dependent FMN reductase
AL536_11165	COG0697	spore germination
AL536_11175	COG1278	Cold shock
AL536_11195	COG2207	Transcriptional regulator
AL536_11200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_11205	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AL536_11205	COG0674	pyruvate-flavodoxin oxidoreductase activity
AL536_11210	COG1013	pyruvate-flavodoxin oxidoreductase activity
AL536_11215	COG1881	PFAM PEBP family protein
AL536_11220	COG2207	Transcriptional regulator
AL536_11250	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL536_11255	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL536_11270	COG0642	Histidine kinase
AL536_11275	COG0745	RESPONSE REGULATOR receiver
AL536_11280	COG0671	phosphoesterase, PA-phosphatase related
AL536_11290	COG0513	Belongs to the DEAD box helicase family
AL536_11295	COG1368	sulfuric ester hydrolase activity
AL536_11300	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL536_11305	COG2194	sulfuric ester hydrolase activity
AL536_11325	COG4566	intracellular signal transduction
AL536_11350	COG2863	cytochrome
AL536_11355	COG3258	Cytochrome c
AL536_11370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL536_11375	COG1271	oxidase subunit
AL536_11380	COG1294	oxidase, subunit
AL536_11415	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL536_11420	COG2814	Major facilitator Superfamily
AL536_11430	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL536_11435	COG1169	isochorismate synthase
AL536_11440	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_11445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL536_11450	COG2226	methyltransferase
AL536_11450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL536_11450	COG3433	isochorismatase activity
AL536_11465	COG4592	Periplasmic binding protein
AL536_11470	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_11475	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL536_11480	COG4774	siderophore transport
AL536_11480	COG1629	transport
AL536_11490	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL536_11495	COG1120	ATPase activity
AL536_11505	COG1609	Transcriptional regulator
AL536_11510	COG2723	6-phospho-beta-galactosidase activity
AL536_11515	COG1741	Belongs to the pirin family
AL536_11520	COG0352	thiamine-phosphate diphosphorylase activity
AL536_11530	COG0351	phosphomethylpyrimidine kinase
AL536_11540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL536_11545	COG0601	transmembrane transport
AL536_11550	COG0747	negative chemotaxis
AL536_11560	COG1538	Outer membrane efflux protein
AL536_11565	COG1566	PFAM secretion protein HlyD family protein
AL536_11570	COG2814	Major facilitator Superfamily
AL536_11575	COG3708	Transcriptional regulator
AL536_11575	COG2207	Transcriptional regulator
AL536_11585	COG0745	RESPONSE REGULATOR receiver
AL536_11595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL536_11595	COG1263	PTS System
AL536_11605	COG1621	beta-fructofuranosidase activity
AL536_11610	COG2199	diguanylate cyclase activity
AL536_11610	COG2200	EAL domain
AL536_11610	COG2202	Pas domain
AL536_11620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL536_11635	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_11670	COG2986	histidine ammonia-lyase
AL536_11675	COG1216	Glycosyl transferase, family 2
AL536_11685	COG0318	PFAM AMP-dependent synthetase and ligase
AL536_11695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL536_11700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL536_11705	COG0204	Acyl-transferase
AL536_11705	COG0318	PFAM AMP-dependent synthetase and ligase
AL536_11735	COG0601	transmembrane transport
AL536_11740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL536_11745	COG0444	Belongs to the ABC transporter superfamily
AL536_11760	COG0435	Glutathione S-transferase
AL536_11765	COG3174	membrane
AL536_11770	COG0280	phosphate acetyltransferase
AL536_11770	COG0857	belongs to the CobB CobQ family
AL536_11775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL536_11780	COG3092	negative regulation of chromosome organization
AL536_11790	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL536_11800	COG3706	GGDEF domain
AL536_11815	COG0653	protein targeting
AL536_11820	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL536_11825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL536_11830	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL536_11840	COG0243	molybdopterin cofactor binding
AL536_11845	COG1648	precorrin-2 dehydrogenase activity
AL536_11845	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL536_11860	COG1116	anion transmembrane transporter activity
AL536_11860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL536_11865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL536_11870	COG1116	anion transmembrane transporter activity
AL536_11875	COG2146	nitrite reductase [NAD(P)H] activity
AL536_11875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL536_11885	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL536_11890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AL536_11900	COG2226	methyltransferase
AL536_11905	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AL536_11910	COG0501	Belongs to the peptidase M48B family
AL536_11920	COG1028	Short-chain dehydrogenase reductase Sdr
AL536_11935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL536_11955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL536_11960	COG2915	High frequency lysogenization protein hflD homolog
AL536_11965	COG0482	sulfurtransferase activity
AL536_11970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL536_11975	COG2916	Histone family protein nucleoid-structuring protein H-NS
AL536_11980	COG1757	Na H antiporter
AL536_11990	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL536_11995	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL536_12000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL536_12005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL536_12005	COG0131	Imidazoleglycerol-phosphate dehydratase
AL536_12010	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL536_12015	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL536_12025	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL536_12025	COG0140	phosphoribosyl-ATP diphosphatase activity
AL536_12030	COG1187	pseudouridine synthase activity
AL536_12040	COG1278	Cold shock
AL536_12045	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AL536_12050	COG0542	response to heat
AL536_12055	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL536_12060	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL536_12065	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL536_12075	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL536_12085	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL536_12090	COG0745	RESPONSE REGULATOR receiver
AL536_12090	COG3706	GGDEF domain
AL536_12095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL536_12100	COG0297	glycogen (starch) synthase activity
AL536_12120	COG3070	regulator of competence-specific genes
AL536_12125	COG1609	Transcriptional regulator
AL536_12130	COG3381	protein complex oligomerization
AL536_12135	COG0745	RESPONSE REGULATOR receiver
AL536_12140	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL536_12145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL536_12150	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
AL536_12155	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AL536_12160	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL536_12165	COG0189	ligase activity
AL536_12175	COG4067	protein conserved in archaea
AL536_12175	COG0189	ligase activity
AL536_12180	COG0500	methyltransferase
AL536_12185	COG4106	trans-aconitate 2-methyltransferase activity
AL536_12200	COG1435	thymidine kinase activity
AL536_12210	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL536_12230	COG2116	formate transmembrane transporter activity
AL536_12235	COG0390	transport system, permease component
AL536_12240	COG4459	periplasmic nitrate reductase
AL536_12245	COG3005	denitrification pathway
AL536_12250	COG0243	molybdopterin cofactor binding
AL536_12270	COG1227	inorganic diphosphatase activity
AL536_12285	COG4172	Belongs to the ABC transporter superfamily
AL536_12295	COG4171	peptide transport system, permease
AL536_12300	COG4168	peptide transport system, permease
AL536_12310	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL536_12315	COG1842	Phage shock protein A
AL536_12330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL536_12345	COG0519	Catalyzes the synthesis of GMP from XMP
AL536_12375	COG0626	cystathionine gamma-synthase activity
AL536_12385	COG0733	neurotransmitter:sodium symporter activity
AL536_12405	COG0564	pseudouridine synthase activity
AL536_12415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL536_12420	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL536_12425	COG4136	ATPase activity
AL536_12430	COG4135	transport system, permease component
AL536_12435	COG4134	Bacterial extracellular solute-binding protein
AL536_12445	COG3313	Fe-S protein
AL536_12455	COG0842	Transport permease protein
AL536_12460	COG1131	(ABC) transporter
AL536_12470	COG0814	amino acid
AL536_12485	COG3706	GGDEF domain
AL536_12490	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL536_12500	COG1278	Cold shock
AL536_12510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL536_12520	COG3119	arylsulfatase activity
AL536_12525	COG0641	radical SAM
AL536_12530	COG0714	Associated with various cellular activities
AL536_12565	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL536_12570	COG2205	protein histidine kinase activity
AL536_12575	COG0745	RESPONSE REGULATOR receiver
AL536_12585	COG1061	Type III restriction enzyme res subunit
AL536_12595	COG2814	Major facilitator Superfamily
AL536_12605	COG0702	epimerase
AL536_12610	COG0534	Mate efflux family protein
AL536_12615	COG4181	ATPase activity
AL536_12630	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL536_12675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL536_12690	COG3265	gluconokinase activity
AL536_12695	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL536_12725	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL536_12730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL536_12745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL536_12770	COG2989	Protein conserved in bacteria
AL536_12775	COG3108	Peptidase M15
AL536_12780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL536_12795	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL536_12815	COG2197	response regulator
AL536_12820	COG1846	Transcriptional regulator
AL536_12825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL536_12830	COG0840	transmembrane signaling receptor activity
AL536_12835	COG2176	DNA-directed DNA polymerase activity
AL536_12840	COG0517	IMP dehydrogenase activity
AL536_12850	COG1448	Aminotransferase
AL536_12870	COG0840	transmembrane signaling receptor activity
AL536_12875	COG0720	synthase
AL536_12880	COG1538	Outer membrane efflux protein
AL536_12885	COG0577	efflux transmembrane transporter activity
AL536_12885	COG1136	(ABC) transporter
AL536_12890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL536_12895	COG1760	l-serine dehydratase
AL536_12900	COG0814	amino acid
AL536_12905	COG0494	nUDIX hydrolase
AL536_12920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL536_12935	COG3106	COG3106 Predicted ATPase
AL536_12945	COG3283	Transcriptional regulator of aromatic amino acids metabolism
AL536_12950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL536_12970	COG0471	metal ion transport
AL536_12975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL536_12975	COG4191	Histidine kinase
AL536_12985	COG0583	DNA-binding transcription factor activity
AL536_12990	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL536_12995	COG0778	Nitroreductase
AL536_13000	COG2991	Protein conserved in bacteria
AL536_13010	COG3250	beta-galactosidase activity
AL536_13020	COG1129	ABC transporter
AL536_13055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL536_13055	COG2169	Transcriptional regulator
AL536_13065	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AL536_13070	COG0372	Belongs to the citrate synthase family
AL536_13075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AL536_13080	COG2828	Protein conserved in bacteria
AL536_13095	COG1566	PFAM secretion protein HlyD family protein
AL536_13100	COG2814	Major facilitator Superfamily
AL536_13115	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL536_13120	COG2200	EAL domain
AL536_13130	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL536_13140	COG0625	glutathione transferase activity
AL536_13160	COG2731	YhcH YjgK YiaL family protein
AL536_13165	COG0584	glycerophosphoryl diester phosphodiesterase
AL536_13170	COG1349	DNA-binding transcription factor activity
AL536_13175	COG3842	ATPase activity
AL536_13180	COG0395	ABC-type sugar transport system, permease component
AL536_13200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL536_13205	COG3040	lipid binding
AL536_13215	COG0811	peptide transport
AL536_13220	COG0811	peptide transport
AL536_13225	COG0848	biopolymer transport protein
AL536_13245	COG4667	esterase of the alpha-beta hydrolase superfamily
AL536_13250	COG1793	dna ligase
AL536_13265	COG0307	riboflavin synthase, alpha
AL536_13285	COG0791	NLP P60 protein
AL536_13290	COG0840	transmembrane signaling receptor activity
AL536_13305	COG1940	carbohydrate kinase activity
AL536_13315	COG0303	'Molybdopterin
AL536_13320	COG0746	molybdenum cofactor guanylyltransferase activity
AL536_13325	COG3842	ATPase activity
AL536_13330	COG4662	Binding-protein-dependent transport system inner membrane component
AL536_13340	COG2204	response regulator
AL536_13345	COG3852	Histidine kinase
AL536_13360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL536_13380	COG3381	protein complex oligomerization
AL536_13395	COG0437	4 iron, 4 sulfur cluster binding
AL536_13410	COG0004	ammonium transporteR
AL536_13415	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL536_13420	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL536_13425	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL536_13430	COG1177	transmembrane transport
AL536_13435	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL536_13440	COG3842	ATPase activity
AL536_13465	COG0589	response to stress
AL536_13470	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL536_13485	COG2217	Heavy metal translocating P-type atpase
AL536_13495	COG2010	Cytochrome c
AL536_13510	COG3278	Belongs to the heme-copper respiratory oxidase family
AL536_13620	COG3120	sequence-specific DNA binding
AL536_13625	COG1067	ATP-dependent peptidase activity
AL536_13630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL536_13655	COG0116	Belongs to the methyltransferase superfamily
AL536_13655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL536_13665	COG0167	dihydroorotate dehydrogenase activity
AL536_13675	COG0308	aminopeptidase N
AL536_13700	COG1956	GAF domain-containing protein
AL536_13705	COG1132	(ABC) transporter
AL536_13710	COG2995	paraquat-inducible protein a
AL536_13715	COG3008	intermembrane lipid transfer
AL536_13720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL536_13720	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
AL536_13725	COG2996	Protein conserved in bacteria
AL536_13740	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL536_13740	COG0574	Belongs to the PEP-utilizing enzyme family
AL536_13745	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL536_13755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL536_13765	COG1115	amino acid carrier protein
AL536_13790	COG3501	Rhs element vgr protein
AL536_13800	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL536_13810	COG1643	Atp-dependent helicase
AL536_13815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL536_13825	COG3005	denitrification pathway
AL536_13850	COG3706	GGDEF domain
AL536_13865	COG0443	Heat shock 70 kDa protein
AL536_13870	COG3706	GGDEF domain
AL536_13880	COG5001	Diguanylate cyclase
AL536_13880	COG3300	MHYT domain
AL536_13895	COG2999	glutathione oxidoreductase activity
AL536_13915	COG0745	RESPONSE REGULATOR receiver
AL536_13915	COG3706	GGDEF domain
AL536_13925	COG0243	molybdopterin cofactor binding
AL536_13930	COG3005	denitrification pathway
AL536_13940	COG0602	queuosine metabolic process
AL536_13945	COG0561	phosphatase activity
AL536_13955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL536_13960	COG4597	amino acid ABC transporter
AL536_13965	COG0765	amino acid transport
AL536_13970	COG1126	abc transporter atp-binding protein
AL536_13975	COG0670	Belongs to the BI1 family
AL536_13980	COG2920	part of a sulfur-relay system
AL536_13985	COG1254	Belongs to the acylphosphatase family
AL536_13990	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL536_13995	COG3391	amine dehydrogenase activity
AL536_14035	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AL536_14040	COG5002	protein histidine kinase activity
AL536_14045	COG0745	RESPONSE REGULATOR receiver
AL536_14060	COG0668	transmembrane transport
AL536_14090	COG1278	Cold shock
AL536_14130	COG3706	GGDEF domain
AL536_14130	COG0745	RESPONSE REGULATOR receiver
AL536_14145	COG0835	chemotaxis
AL536_14145	COG0784	Response regulator, receiver
AL536_14155	COG4565	transcriptional regulatory protein
AL536_14160	COG3290	protein histidine kinase activity
AL536_14175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL536_14195	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AL536_14200	COG3063	Type IV pilus biogenesis stability protein PilW
AL536_14215	COG1451	nucleotide metabolic process
AL536_14225	COG0583	DNA-binding transcription factor activity
AL536_14275	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
AL536_14280	COG4139	cobalamin transport
AL536_14285	COG2988	succinylglutamate desuccinylase activity
AL536_14300	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AL536_14305	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AL536_14310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL536_14315	COG0702	epimerase
AL536_14330	COG2925	Exonuclease
AL536_14340	COG1346	cytolysis
AL536_14345	COG0295	cytidine deaminase activity
AL536_14350	COG5001	Diguanylate cyclase
AL536_14370	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL536_14380	COG0500	methyltransferase
AL536_14390	COG0776	regulation of translation
AL536_14395	COG0072	phenylalanine-tRNA ligase activity
AL536_14395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL536_14400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL536_14415	COG0745	RESPONSE REGULATOR receiver
AL536_14415	COG3706	GGDEF domain
AL536_14420	COG2133	pyrroloquinoline quinone binding
AL536_14455	COG0322	excinuclease ABC activity
AL536_14460	COG2197	response regulator
AL536_14465	COG0417	DNA replication proofreading
AL536_14470	COG5001	Diguanylate cyclase
AL536_14480	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL536_14500	COG1228	amidohydrolase
AL536_14505	COG0010	Belongs to the arginase family
AL536_14515	COG2986	histidine ammonia-lyase
AL536_14535	COG0247	lactate metabolic process
AL536_14535	COG0277	FAD linked oxidase domain protein
AL536_14550	COG2885	chlorophyll binding
AL536_14575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL536_14580	COG1012	belongs to the aldehyde dehydrogenase family
AL536_14585	COG2957	Belongs to the agmatine deiminase family
AL536_14595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL536_14600	COG1012	belongs to the aldehyde dehydrogenase family
AL536_14605	COG1396	sequence-specific DNA binding
AL536_14605	COG1917	Cupin 2, conserved barrel domain protein
AL536_14610	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AL536_14615	COG0174	glutamine synthetase
AL536_14630	COG1643	Atp-dependent helicase
AL536_14635	COG0281	malic enzyme
AL536_14655	COG0583	DNA-binding transcription factor activity
AL536_14670	COG0640	Transcriptional regulator
AL536_14695	COG2949	membrane
AL536_14705	COG1414	Transcriptional regulator
AL536_14710	COG1414	Transcriptional regulator
AL536_14720	COG1454	alcohol dehydrogenase
AL536_14725	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL536_14745	COG0492	ferredoxin-NADP+ reductase activity
AL536_14750	COG4988	ABC transporter
AL536_14755	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL536_14785	COG1187	pseudouridine synthase activity
AL536_14790	COG0009	L-threonylcarbamoyladenylate synthase
AL536_14795	COG0613	PHP domain protein
AL536_14800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL536_14805	COG0512	Glutamine amidotransferase of anthranilate synthase
AL536_14810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL536_14815	COG0134	indole-3-glycerol-phosphate synthase activity
AL536_14815	COG0135	phosphoribosylanthranilate isomerase activity
AL536_14820	COG0133	tryptophan synthase activity
AL536_14830	COG1301	dicarboxylic acid transport
AL536_14845	COG1607	acyl-coa hydrolase
AL536_14850	COG2350	Protein conserved in bacteria
AL536_14860	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL536_14865	COG0583	DNA-binding transcription factor activity
AL536_14880	COG0612	Peptidase, M16
AL536_14900	COG0625	glutathione transferase activity
AL536_14910	COG2200	EAL domain
AL536_14910	COG2771	luxR family
AL536_14915	COG0840	transmembrane signaling receptor activity
AL536_14930	COG1794	racemase activity, acting on amino acids and derivatives
AL536_14935	COG0346	lactoylglutathione lyase activity
AL536_14940	COG5002	protein histidine kinase activity
AL536_14945	COG0745	RESPONSE REGULATOR receiver
AL536_14965	COG0488	(ABC) transporter
AL536_14970	COG1032	radical SAM domain protein
AL536_14975	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL536_14985	COG3852	Histidine kinase
AL536_15000	COG3070	regulator of competence-specific genes
AL536_15010	COG2431	L-lysine efflux transmembrane transporter activity
AL536_15020	COG0076	glutamate decarboxylase activity
AL536_15025	COG1737	Transcriptional regulator
AL536_15030	COG1979	alcohol dehydrogenase
AL536_15035	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL536_15045	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL536_15050	COG1960	acyl-CoA dehydrogenase activity
AL536_15070	COG1012	belongs to the aldehyde dehydrogenase family
AL536_15085	COG0784	Response regulator, receiver
AL536_15085	COG5002	protein histidine kinase activity
AL536_15095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL536_15100	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL536_15105	COG2885	chlorophyll binding
AL536_15125	COG0811	peptide transport
AL536_15130	COG0824	Thioesterase
AL536_15140	COG4890	Cyd operon protein YbgT
AL536_15145	COG1294	oxidase, subunit
AL536_15150	COG1271	oxidase subunit
AL536_15155	COG2255	four-way junction helicase activity
AL536_15160	COG0632	four-way junction helicase activity
AL536_15165	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AL536_15170	COG0215	cysteine-tRNA ligase activity
AL536_15175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL536_15180	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL536_15185	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL536_15190	COG3012	SEC-C Motif Domain Protein
AL536_15200	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL536_15205	COG1199	ATP-dependent helicase activity
AL536_15210	COG3923	Primosomal replication protein n
AL536_15225	COG0708	Exodeoxyribonuclease III
AL536_15230	COG4160	amino acid transport
AL536_15235	COG4215	(ABC) transporter
AL536_15255	COG1882	Formate acetyltransferase
AL536_15270	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL536_15290	COG2766	serine protein kinase
AL536_15295	COG2718	Belongs to the UPF0229 family
AL536_15300	COG2719	SpoVR family
AL536_15305	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL536_15320	COG1132	(ABC) transporter
AL536_15325	COG2333	competence protein COMEC
AL536_15325	COG0658	competence protein
AL536_15335	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL536_15340	COG1136	(ABC) transporter
AL536_15345	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL536_15355	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL536_15370	COG1252	NADH dehydrogenase
AL536_15400	COG0537	adenosine 5'-monophosphoramidase activity
AL536_15415	COG2186	Transcriptional regulator
AL536_15420	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL536_15425	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL536_15430	COG1674	ftsk spoiiie
AL536_15435	COG1522	sequence-specific DNA binding
AL536_15440	COG0686	Belongs to the AlaDH PNT family
AL536_15450	COG0583	DNA-binding transcription factor activity
AL536_15470	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL536_15475	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL536_15485	COG0539	negative regulation of cytoplasmic translation
AL536_15490	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL536_15495	COG1555	photosystem II stabilization
AL536_15500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL536_15505	COG0776	regulation of translation
AL536_15510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL536_15515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL536_15525	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL536_15530	COG4191	Histidine kinase
AL536_15535	COG2204	response regulator
AL536_15540	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL536_15545	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL536_15550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL536_15555	COG1404	Belongs to the peptidase S8 family
AL536_15560	COG1653	transport
AL536_15570	COG0745	RESPONSE REGULATOR receiver
AL536_15580	COG1760	l-serine dehydratase
AL536_15590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL536_15590	COG3153	acetyltransferase
AL536_15600	COG5001	Diguanylate cyclase
AL536_15600	COG1716	ATPase activity
AL536_15610	COG4589	Belongs to the CDS family
AL536_15645	COG2197	response regulator
AL536_15650	COG3851	Histidine kinase
AL536_15655	COG2271	Major facilitator Superfamily
AL536_15660	COG1840	ABC-type Fe3 transport system, periplasmic component
AL536_15670	COG3842	ATPase activity
AL536_15680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL536_15685	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL536_15695	COG2951	lytic endotransglycosylase activity
AL536_15700	COG3100	YcgL domain-containing protein
AL536_15710	COG2894	cell division
AL536_15715	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL536_15725	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL536_15730	COG0318	PFAM AMP-dependent synthetase and ligase
AL536_15750	COG1214	PFAM Peptidase M22, glycoprotease
AL536_15755	COG1199	ATP-dependent helicase activity
AL536_15765	COG0788	formyltetrahydrofolate deformylase activity
AL536_15770	COG1902	pentaerythritol trinitrate reductase activity
AL536_15770	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL536_15775	COG0616	signal peptide processing
AL536_15780	COG0252	asparaginase activity
AL536_15785	COG3139	Protein of unknown function (DUF1315)
AL536_15795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL536_15800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL536_15810	COG2226	methyltransferase
AL536_15835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL536_15840	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL536_15845	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AL536_15855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL536_15860	COG2832	Protein of unknown function (DUF454)
AL536_15865	COG0745	RESPONSE REGULATOR receiver
AL536_15870	COG0583	DNA-binding transcription factor activity
AL536_15875	COG0778	Nitroreductase
AL536_15880	COG1024	Enoyl-CoA hydratase
AL536_15880	COG1250	3-hydroxyacyl-CoA dehydrogenase
AL536_15885	COG0183	Belongs to the thiolase family
AL536_15900	COG2067	long-chain fatty acid transport protein
AL536_15910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL536_15925	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AL536_15930	COG2982	Protein involved in outer membrane biogenesis
AL536_15935	COG0572	uridine kinase
AL536_15940	COG0489	protein tyrosine kinase activity
AL536_15945	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL536_15945	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL536_15955	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AL536_15965	COG0516	GMP reductase activity
AL536_15965	COG0517	IMP dehydrogenase activity
AL536_15970	COG3706	GGDEF domain
AL536_15975	COG0314	molybdopterin synthase activity
AL536_15980	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL536_15985	COG0315	cyclic pyranopterin monophosphate synthase activity
AL536_15990	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL536_15995	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL536_16000	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AL536_16005	COG2198	Histidine kinase
AL536_16010	COG2204	response regulator
AL536_16025	COG0582	viral genome integration into host DNA
AL536_16045	COG4251	negative regulation of phosphorylation
AL536_16045	COG5001	Diguanylate cyclase
AL536_16045	COG2203	Gaf domain
AL536_16045	COG3706	GGDEF domain
AL536_16110	COG4657	Part of a membrane complex involved in electron transport
AL536_16115	COG2878	Part of a membrane complex involved in electron transport
AL536_16120	COG4656	Part of a membrane complex involved in electron transport
AL536_16125	COG4658	electron transport chain
AL536_16130	COG4659	FMN binding
AL536_16135	COG4660	Part of a membrane complex involved in electron transport
AL536_16140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL536_16145	COG0346	lactoylglutathione lyase activity
AL536_16160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL536_16165	COG2056	Na+-H+ antiporter family
AL536_16170	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL536_16175	COG1286	toxin biosynthetic process
AL536_16180	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL536_16185	COG0285	dihydrofolate synthase activity
AL536_16195	COG0101	tRNA pseudouridine synthase activity
AL536_16205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL536_16210	COG2190	(PTS) system
AL536_16210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL536_16210	COG1263	PTS System
AL536_16215	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL536_16220	COG1846	Transcriptional regulator
AL536_16220	COG1940	carbohydrate kinase activity
AL536_16225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL536_16225	COG4651	solute:proton antiporter activity
AL536_16230	COG0367	asparagine synthase
AL536_16240	COG3104	oligopeptide transport
AL536_16245	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL536_16255	COG0326	Molecular chaperone. Has ATPase activity
AL536_16260	COG3710	Transcriptional regulator
AL536_16275	COG0622	Phosphoesterase
AL536_16300	COG1090	epimerase
AL536_16305	COG0300	oxidoreductase activity
AL536_16310	COG3118	belongs to the thioredoxin family
AL536_16315	COG0330	HflC and HflK could
AL536_16325	COG0789	Transcriptional regulator
AL536_16340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL536_16345	COG3115	cell septum assembly
AL536_16350	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AL536_16355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL536_16360	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_16370	COG2190	(PTS) system
AL536_16375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL536_16380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL536_16385	COG1702	phosphate starvation-inducible protein PhoH
AL536_16390	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AL536_16395	COG4535	Mg2 and Co2 transporter CorC
AL536_16400	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL536_16405	COG2888	peptidyl-tyrosine sulfation
AL536_16415	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AL536_16420	COG1466	dna polymerase III delta subunit
AL536_16425	COG0799	negative regulation of ribosome biogenesis
AL536_16430	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL536_16435	COG0768	penicillin binding
AL536_16440	COG0772	Belongs to the SEDS family
AL536_16445	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL536_16450	COG1686	Belongs to the peptidase S11 family
AL536_16455	COG2921	Belongs to the UPF0250 family
AL536_16460	COG0321	lipoyl(octanoyl) transferase activity
AL536_16465	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL536_16475	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL536_16485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL536_16490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL536_16515	COG0366	Alpha amylase catalytic
AL536_16520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL536_16520	COG1263	PTS System
AL536_16535	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL536_16540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL536_16545	COG2011	ABC-type metal ion transport system permease component
AL536_16550	COG1464	Belongs to the NlpA lipoprotein family
AL536_16555	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AL536_16565	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL536_16565	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL536_16575	COG3706	GGDEF domain
AL536_16575	COG0745	RESPONSE REGULATOR receiver
AL536_16580	COG1611	Belongs to the LOG family
AL536_16585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL536_16595	COG2363	Small membrane protein
AL536_16605	COG0583	DNA-binding transcription factor activity
AL536_16610	COG0301	tRNA thio-modification
AL536_16610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL536_16620	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL536_16630	COG0142	geranyltranstransferase activity
AL536_16635	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL536_16640	COG0564	pseudouridine synthase activity
AL536_16645	COG3098	single-species biofilm formation
AL536_16670	COG1671	Belongs to the UPF0178 family
AL536_16675	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL536_16680	COG0254	rRNA binding
AL536_16685	COG1720	tRNA m6t6A37 methyltransferase activity
AL536_16690	COG0442	prolyl-tRNA aminoacylation
AL536_16715	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL536_16720	COG0590	tRNA wobble adenosine to inosine editing
AL536_16725	COG0583	DNA-binding transcription factor activity
AL536_16730	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AL536_16735	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AL536_16740	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL536_16765	COG4969	Belongs to the N-Me-Phe pilin family
AL536_16775	COG0443	Heat shock 70 kDa protein
AL536_16785	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL536_16790	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL536_16795	COG0497	DNA recombination
AL536_16800	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL536_16805	COG2914	Belongs to the UPF0125 (RnfH) family
AL536_16810	COG2867	negative regulation of translational initiation
AL536_16815	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AL536_16825	COG0582	viral genome integration into host DNA
AL536_16840	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL536_16860	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL536_16880	COG2003	Belongs to the UPF0758 family
AL536_16910	COG1160	GTP binding
AL536_16920	COG0328	RNA-DNA hybrid ribonuclease activity
AL536_16960	COG3501	Rhs element vgr protein
AL536_16985	COG1401	restriction endodeoxyribonuclease activity
AL536_16990	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
AL536_16990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL536_17010	COG0583	DNA-binding transcription factor activity
AL536_17015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL536_17020	COG1115	amino acid carrier protein
AL536_17030	COG1473	amidohydrolase
AL536_17045	COG1584	GPR1 FUN34 yaaH family protein
AL536_17055	COG0519	Catalyzes the synthesis of GMP from XMP
AL536_17055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL536_17060	COG0517	IMP dehydrogenase activity
AL536_17060	COG0516	GMP reductase activity
AL536_17065	COG1570	exodeoxyribonuclease VII activity
AL536_17080	COG1160	GTP binding
AL536_17085	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL536_17090	COG2976	Protein conserved in bacteria
AL536_17095	COG0124	histidyl-tRNA synthetase
AL536_17100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL536_17120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL536_17125	COG2975	iron-sulfur cluster assembly
AL536_17130	COG0633	Ferredoxin
AL536_17135	COG0443	Heat shock 70 kDa protein
AL536_17150	COG0822	iron-sulfur transferase activity
AL536_17155	COG1104	cysteine desulfurase activity
AL536_17160	COG1959	2 iron, 2 sulfur cluster binding
AL536_17165	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL536_17170	COG0483	inositol monophosphate 1-phosphatase activity
AL536_17175	COG1335	isochorismatase
AL536_17180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL536_17185	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL536_17190	COG1862	Preprotein translocase
AL536_17195	COG0343	queuine tRNA-ribosyltransferase activity
AL536_17200	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL536_17205	COG0517	IMP dehydrogenase activity
AL536_17215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL536_17220	COG0583	DNA-binding transcription factor activity
AL536_17225	COG0450	alkyl hydroperoxide reductase
AL536_17240	COG0704	Plays a role in the regulation of phosphate uptake
AL536_17245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL536_17250	COG0581	inorganic phosphate transmembrane transporter activity
AL536_17255	COG0573	inorganic phosphate transmembrane transporter activity
AL536_17260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL536_17265	COG0248	Ppx GppA phosphatase
AL536_17275	COG5002	protein histidine kinase activity
AL536_17280	COG0745	RESPONSE REGULATOR receiver
AL536_17285	COG2974	May be involved in recombination
AL536_17295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL536_17300	COG0477	Major facilitator Superfamily
AL536_17310	COG1595	DNA-templated transcription, initiation
AL536_17320	COG3248	Nucleoside-binding outer membrane protein
AL536_17325	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL536_17330	COG0693	protein deglycase activity
AL536_17335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL536_17345	COG2166	iron-sulfur cluster assembly
AL536_17350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL536_17355	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL536_17365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL536_17365	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL536_17375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL536_17380	COG1074	ATP-dependent DNA helicase activity
AL536_17385	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL536_17395	COG0583	DNA-binding transcription factor activity
AL536_17400	COG3141	response to X-ray
AL536_17405	COG2171	N-acyltransferase activity
AL536_17410	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL536_17425	COG0569	domain protein
AL536_17425	COG0189	ligase activity
AL536_17440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL536_17445	COG2017	converts alpha-aldose to the beta-anomer
AL536_17455	COG2059	Chromate
AL536_17460	COG3437	response regulator, receiver
AL536_17460	COG0784	Response regulator, receiver
AL536_17510	COG4964	Belongs to the GSP D family
AL536_17550	COG0583	DNA-binding transcription factor activity
AL536_17555	COG0583	DNA-binding transcription factor activity
AL536_17560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL536_17565	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AL536_17575	COG0560	Phosphoserine phosphatase
AL536_17585	COG0813	purine-nucleoside phosphorylase activity
AL536_17590	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AL536_17595	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AL536_17600	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AL536_17605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL536_17630	COG0084	hydrolase, TatD family'
AL536_17635	COG3022	response to hydroperoxide
AL536_17640	COG1115	amino acid carrier protein
AL536_17655	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL536_17670	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL536_17675	COG0083	homoserine kinase activity
AL536_17690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL536_17700	COG0745	RESPONSE REGULATOR receiver
AL536_17710	COG0784	Response regulator, receiver
AL536_17710	COG5002	protein histidine kinase activity
AL536_17710	COG2198	Histidine kinase
AL536_17715	COG4251	negative regulation of phosphorylation
AL536_17715	COG2203	Gaf domain
AL536_17715	COG3706	GGDEF domain
AL536_17715	COG5001	Diguanylate cyclase
AL536_17720	COG1242	4 iron, 4 sulfur cluster binding
AL536_17725	COG0067	glutamate synthase
AL536_17725	COG0070	glutamate synthase
AL536_17725	COG0069	glutamate synthase activity
AL536_17735	COG0069	glutamate synthase activity
AL536_17735	COG0070	glutamate synthase
AL536_17735	COG0067	glutamate synthase
AL536_17740	COG0493	'glutamate synthase
AL536_17760	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL536_17765	COG2860	membrane
AL536_17785	COG0583	DNA-binding transcription factor activity
AL536_17790	COG0730	response to heat
AL536_17800	COG0505	Belongs to the CarA family
AL536_17810	COG0494	nUDIX hydrolase
AL536_17815	COG0653	protein targeting
AL536_17825	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL536_17830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL536_17835	COG0849	cell division
AL536_17840	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL536_17845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL536_17850	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL536_17855	COG0772	Belongs to the SEDS family
AL536_17860	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL536_17865	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL536_17870	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL536_17875	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL536_17880	COG0768	penicillin binding
AL536_17885	COG3116	cell division
AL536_17890	COG0275	rRNA processing
AL536_17900	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL536_17905	COG3107	peptidoglycan biosynthetic process
AL536_17910	COG0792	nuclease activity
AL536_17915	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL536_17920	COG2823	Periplasmic or secreted lipoprotein
AL536_17925	COG2969	positive regulation of protein catabolic process
AL536_17930	COG0625	glutathione transferase activity
AL536_17935	COG2857	Cytochrome c1
AL536_17940	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL536_17945	COG0723	plastoquinol--plastocyanin reductase activity
AL536_17950	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL536_17955	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL536_17960	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL536_17965	COG3105	Protein conserved in bacteria
AL536_17970	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL536_17975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL536_17980	COG0335	large ribosomal subunit rRNA binding
AL536_17990	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL536_18000	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL536_18005	COG4137	Cytochrome C assembly protein
AL536_18010	COG4536	flavin adenine dinucleotide binding
AL536_18015	COG1854	S-ribosylhomocysteine lyase activity
AL536_18030	COG0612	Peptidase, M16
AL536_18035	COG1238	metal cluster binding
AL536_18040	COG1063	alcohol dehydrogenase
AL536_18045	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AL536_18050	COG5016	pyruvate
AL536_18050	COG0511	ligase activity, forming carbon-carbon bonds
AL536_18055	COG3630	sodium ion export across plasma membrane
AL536_18105	COG0527	aspartate kinase activity
AL536_18110	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL536_18120	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL536_18125	COG1546	Belongs to the CinA family
AL536_18130	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AL536_18135	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL536_18140	COG1388	LysM domain
AL536_18140	COG4942	peptidase
AL536_18150	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL536_18155	COG0585	pseudouridine synthase activity
AL536_18165	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL536_18170	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL536_18175	COG1968	undecaprenyl-diphosphatase activity
AL536_18180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL536_18185	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL536_18190	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL536_18200	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL536_18205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL536_18210	COG1610	YqeY-like protein
AL536_18220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL536_18240	COG2239	Acts as a magnesium transporter
AL536_18260	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL536_18295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL536_18325	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
AL536_18330	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL536_18335	COG1349	DNA-binding transcription factor activity
AL536_18340	COG0469	pyruvate kinase activity
AL536_18345	COG3706	GGDEF domain
AL536_18370	COG0668	transmembrane transport
AL536_18375	COG0191	fructose-bisphosphate aldolase activity
AL536_18380	COG0126	phosphoglycerate kinase activity
AL536_18385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL536_18390	COG4771	TonB-dependent receptor
AL536_18395	COG0583	DNA-binding transcription factor activity
AL536_18400	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL536_18420	COG2356	endonuclease I
AL536_18425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL536_18430	COG0189	ligase activity
AL536_18435	COG1678	Uncharacterized ACR, COG1678
AL536_18440	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL536_18455	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL536_18460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL536_18465	COG0762	integral membrane protein
AL536_18470	COG1872	DUF167
AL536_18485	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL536_18490	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL536_18495	COG2066	Belongs to the glutaminase family
AL536_18500	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL536_18505	COG1194	a g-specific adenine glycosylase
AL536_18510	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL536_18515	COG0741	lytic transglycosylase activity
AL536_18570	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL536_18575	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL536_18580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL536_18595	COG2967	ApaG domain
AL536_18610	COG3610	response to peptide
AL536_18615	COG2966	Psort location CytoplasmicMembrane, score
AL536_18620	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL536_18625	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AL536_18630	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL536_18635	COG0142	geranyltranstransferase activity
AL536_18640	COG0531	amino acid
AL536_18645	COG0039	L-malate dehydrogenase activity
AL536_18665	COG0589	response to stress
AL536_18685	COG0312	modulator of DNA gyrase
AL536_18690	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL536_18695	COG3164	Protein of unknown function
AL536_18700	COG1530	ribonuclease E activity
AL536_18705	COG0424	maF-like protein
AL536_18710	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL536_18715	COG1792	Involved in formation and maintenance of cell shape
AL536_18720	COG1077	Cell shape determining protein MreB Mrl
AL536_18770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL536_18780	COG3267	Type II secretory pathway component ExeA
AL536_18780	COG3409	Peptidoglycan-binding domain 1 protein
AL536_18805	COG2199	diguanylate cyclase activity
AL536_18805	COG2200	EAL domain
AL536_18810	COG0629	single-stranded DNA binding
AL536_18825	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL536_18835	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL536_18840	COG0527	aspartate kinase activity
AL536_18845	COG1410	methionine synthase
AL536_18845	COG0646	methionine synthase
AL536_18920	COG0175	sulfate reduction
AL536_18930	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL536_18950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL536_18955	COG0735	belongs to the Fur family
AL536_18965	COG0166	Belongs to the GPI family
AL536_18970	COG0432	Pfam Uncharacterised protein family UPF0047
AL536_18975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL536_18980	COG0305	Participates in initiation and elongation during chromosome replication
AL536_18990	COG0359	binds to the 23S rRNA
AL536_19000	COG0360	Binds together with S18 to 16S ribosomal RNA
AL536_19010	COG2906	2 iron, 2 sulfur cluster binding
AL536_19020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL536_19025	COG0049	tRNA binding
AL536_19035	COG2168	tRNA wobble position uridine thiolation
AL536_19040	COG2923	Belongs to the DsrF TusC family
AL536_19050	COG2964	Protein conserved in bacteria
AL536_19055	COG0545	Peptidyl-prolyl cis-trans isomerase
AL536_19065	COG2900	Belongs to the SlyX family
AL536_19070	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL536_19075	COG0330	HflC and HflK could
AL536_19080	COG0330	HflC and HflK could
AL536_19085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL536_19090	COG1923	regulation of RNA biosynthetic process
AL536_19095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL536_19100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL536_19110	COG0802	atpase or kinase
AL536_19115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL536_19170	COG1162	GTPase activity
AL536_19175	COG0688	phosphatidylethanolamine metabolic process
AL536_19180	COG0490	domain, Protein
AL536_19180	COG0471	metal ion transport
AL536_19195	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL536_19200	COG4942	peptidase
AL536_19220	COG2816	NAD+ diphosphatase activity
AL536_19225	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL536_19230	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL536_19235	COG0085	RNA polymerase activity
AL536_19245	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL536_19250	COG0081	regulation of translation
AL536_19255	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL536_19260	COG0250	Participates in transcription elongation, termination and antitermination
AL536_19265	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL536_19300	COG1072	(Pantothenic acid kinase))
AL536_19310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL536_19320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL536_19385	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL536_19395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL536_19400	COG3118	belongs to the thioredoxin family
AL536_19405	COG0513	Belongs to the DEAD box helicase family
AL536_19410	COG0248	Ppx GppA phosphatase
AL536_19415	COG0784	Response regulator, receiver
AL536_19415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL536_19415	COG2198	Histidine kinase
AL536_19415	COG2205	protein histidine kinase activity
AL536_19420	COG2814	Major facilitator Superfamily
AL536_19435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL536_19440	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL536_19445	COG0511	ligase activity, forming carbon-carbon bonds
AL536_19450	COG0439	Biotin carboxylase
AL536_19455	COG2264	protein methyltransferase activity
AL536_19460	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL536_19465	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AL536_19470	COG0840	transmembrane signaling receptor activity
AL536_19475	COG0789	Transcriptional regulator
AL536_19480	COG0138	bifunctional purine biosynthesis protein purh
AL536_19485	COG0151	Belongs to the GarS family
AL536_19495	COG0776	regulation of translation
AL536_19500	COG1253	flavin adenine dinucleotide binding
AL536_19505	COG0668	transmembrane transport
AL536_19510	COG3068	Protein conserved in bacteria
AL536_19515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL536_19520	COG1573	uracil-dna glycosylase
AL536_19525	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL536_19530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL536_19555	COG1086	Polysaccharide biosynthesis protein
AL536_19565	COG0438	transferase activity, transferring glycosyl groups
AL536_19570	COG4641	Protein conserved in bacteria
AL536_19570	COG1388	LysM domain
AL536_19625	COG1596	polysaccharide export
AL536_19645	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL536_19650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL536_19660	COG1560	Kdo2-lipid A biosynthetic process
AL536_19670	COG0859	PFAM glycosyl transferase family 9
AL536_19675	COG0859	PFAM glycosyl transferase family 9
AL536_19680	COG1519	Transferase
AL536_19685	COG0438	transferase activity, transferring glycosyl groups
AL536_19695	COG0859	PFAM glycosyl transferase family 9
AL536_19700	COG0463	Glycosyl transferase, family 2
AL536_19705	COG0438	transferase activity, transferring glycosyl groups
AL536_19710	COG0438	transferase activity, transferring glycosyl groups
AL536_19715	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL536_19730	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL536_19740	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AL536_19760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL536_19765	COG1309	transcriptional regulator
AL536_19770	COG1560	Kdo2-lipid A biosynthetic process
AL536_19775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AL536_19780	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL536_19785	COG1561	YicC-like family, N-terminal region
AL536_19805	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL536_19810	COG1120	ATPase activity
AL536_19815	COG1132	(ABC) transporter
AL536_19830	COG0514	ATP-dependent DNA helicase (RecQ)
AL536_19835	COG2962	Rard protein
AL536_19845	COG1280	lysine exporter protein (LysE YggA)
AL536_19850	COG0405	Gamma-glutamyltransferase
AL536_19855	COG0210	DNA helicase
AL536_19890	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL536_19895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL536_19910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL536_19915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL536_19925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL536_19935	COG0747	negative chemotaxis
AL536_19940	COG4172	Belongs to the ABC transporter superfamily
AL536_19975	COG0210	DNA helicase
AL536_19985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL536_19990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL536_19995	COG2960	long-chain fatty acid transporting porin activity
AL536_20005	COG0583	DNA-binding transcription factor activity
AL536_20045	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL536_20055	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL536_20060	COG0408	coproporphyrinogen oxidase activity
AL536_20075	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL536_20080	COG0551	DNA topoisomerase type I activity
AL536_20085	COG2922	Belongs to the Smg family
AL536_20090	COG0758	DNA mediated transformation
AL536_20095	COG1652	LysM domain
AL536_20100	COG0242	peptide deformylase activity
AL536_20110	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL536_20110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL536_20115	COG0569	domain protein
AL536_20120	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL536_20130	COG1272	protein, Hemolysin III
AL536_20135	COG4326	sporulation control protein
AL536_20140	COG3084	Protein conserved in bacteria
AL536_20150	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL536_20155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL536_20160	COG0204	Acyl-transferase
AL536_20165	COG0606	chelatase, subunit chli
AL536_20175	COG3978	acetolactate synthase activity
AL536_20180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL536_20195	COG0604	alcohol dehydrogenase
AL536_20220	COG2119	membrane
AL536_20225	COG0752	glycyl-tRNA synthetase alpha subunit
AL536_20230	COG0751	glycine-tRNA ligase activity
AL536_20235	COG3977	Valine--pyruvate aminotransferase
AL536_20240	COG0071	Belongs to the small heat shock protein (HSP20) family
AL536_20245	COG0187	DNA topoisomerase II activity
AL536_20250	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL536_20255	COG0592	DNA-directed DNA polymerase activity
AL536_20260	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL536_20275	COG1126	abc transporter atp-binding protein
AL536_20280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL536_20290	COG0706	membrane insertase activity
AL536_20295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL536_20300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL536_20305	COG0445	tRNA wobble uridine modification
AL536_20310	COG0357	Ribosomal RNA small subunit methyltransferase G
AL536_20315	COG1192	Involved in chromosome partitioning
AL536_20320	COG1475	DNA binding
AL536_20325	COG3312	ion transport
AL536_20330	COG0356	it plays a direct role in the translocation of protons across the membrane
AL536_20340	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL536_20345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL536_20355	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL536_20360	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL536_20365	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL536_20375	COG0765	amino acid transport
AL536_20380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL536_20385	COG2814	Major facilitator Superfamily
AL536_20390	COG0583	DNA-binding transcription factor activity
AL536_20395	COG0183	Belongs to the thiolase family
AL536_20405	COG1739	Uncharacterized protein family UPF0029
AL536_20410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL536_20465	COG2132	Multicopper oxidase
AL536_20470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL536_20475	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL536_20485	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL536_20490	COG2104	thiamine diphosphate biosynthetic process
AL536_20490	COG2022	thiamine diphosphate biosynthetic process
AL536_20500	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AL536_20505	COG4175	Glycine betaine
AL536_20535	COG0006	proline dipeptidase activity
AL536_20535	COG0006	proline dipeptidase activity
AL536_20555	COG1522	sequence-specific DNA binding
AL536_20560	COG5002	protein histidine kinase activity
AL536_20560	COG5001	Diguanylate cyclase
AL536_20565	COG0742	ribosomal rna small subunit methyltransferase
AL536_20575	COG0697	spore germination
AL536_20580	COG0589	response to stress
AL536_20585	COG1528	Iron-storage protein
AL536_20595	COG2081	HI0933 family
AL536_20600	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL536_20605	COG1129	ABC transporter
AL536_20610	COG1879	ABC-type sugar transport system periplasmic component
AL536_20615	COG1069	ribulokinase activity
AL536_20620	COG0235	Class ii aldolase
AL536_20625	COG2160	L-arabinose isomerase activity
AL536_20650	COG1322	Protein conserved in bacteria
AL536_20655	COG2226	methyltransferase
AL536_20660	COG3165	ubiquinone biosynthetic process from chorismate
AL536_20665	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL536_20675	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL536_20680	COG0805	protein transport
AL536_20685	COG0084	hydrolase, TatD family'
AL536_20700	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL536_20700	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL536_20705	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL536_20730	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL536_20735	COG3071	HemY protein
AL536_20740	COG2959	enzyme of heme biosynthesis
AL536_20755	COG3072	Adenylate cyclase
AL536_20770	COG0019	diaminopimelate decarboxylase activity
AL536_20775	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL536_20785	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AL536_20790	COG1011	Hydrolase
AL536_20795	COG2199	diguanylate cyclase activity
AL536_20795	COG2200	EAL domain
AL536_20795	COG3287	FIST C domain
AL536_20815	COG0561	phosphatase activity
AL536_20820	COG2267	carboxylic ester hydrolase activity
AL536_20825	COG1280	lysine exporter protein (LysE YggA)
AL536_20830	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL536_20835	COG0640	Transcriptional regulator
AL536_20840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL536_20855	COG0783	Belongs to the Dps family
AL536_20885	COG2095	MarC family integral membrane protein
AL536_20895	COG0742	ribosomal rna small subunit methyltransferase
AL536_20900	COG0552	protein localization to endoplasmic reticulum
AL536_20905	COG2884	Cell division ATP-binding protein ftsE
AL536_20910	COG2177	Part of the ABC transporter FtsEX involved in
AL536_20915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL536_20925	COG0705	Rhomboid family
AL536_20930	COG1580	Controls the rotational direction of flagella during chemotaxis
AL536_20935	COG3161	chorismate lyase activity
AL536_20940	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AL536_20945	COG2937	Belongs to the GPAT DAPAT family
AL536_20950	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL536_20955	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL536_20965	COG0534	Mate efflux family protein
AL536_21015	COG0328	RNA-DNA hybrid ribonuclease activity
AL536_21020	COG1968	undecaprenyl-diphosphatase activity
AL536_21030	COG0668	transmembrane transport
AL536_21035	COG2814	Major facilitator Superfamily
AL536_21040	COG0583	DNA-binding transcription factor activity
AL536_21045	COG2200	EAL domain
AL536_21045	COG2771	luxR family
AL536_21085	COG2003	Belongs to the UPF0758 family
AL536_21110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL536_21125	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AL536_21185	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL536_21190	COG3300	MHYT domain
AL536_21190	COG5001	Diguanylate cyclase
AL536_21195	COG2204	response regulator
AL536_21200	COG3852	Histidine kinase
AL536_21210	COG0174	glutamine synthetase
AL536_21235	COG1490	D-aminoacyl-tRNA deacylase activity
AL536_21240	COG0456	acetyltransferase
AL536_21245	COG2982	Protein involved in outer membrane biogenesis
AL536_21250	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AL536_21255	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AL536_21260	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL536_21265	COG3031	protein transport across the cell outer membrane
AL536_21275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL536_21280	COG1459	type II secretion system
AL536_21285	COG2165	general secretion pathway protein
AL536_21290	COG2165	general secretion pathway protein
AL536_21295	COG2165	general secretion pathway protein
AL536_21300	COG4795	General secretion pathway protein
AL536_21305	COG3156	type II secretion system protein K
AL536_21310	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL536_21315	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL536_21325	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL536_21330	COG0494	nUDIX hydrolase
AL536_21335	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AL536_21335	COG0316	Belongs to the HesB IscA family
AL536_21340	COG1040	competence protein
AL536_21355	COG2183	response to ionizing radiation
AL536_21365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL536_21370	COG1609	Transcriptional regulator
AL536_21375	COG0129	dihydroxy-acid dehydratase activity
AL536_21380	COG3265	gluconokinase activity
AL536_21385	COG2610	gluconate transmembrane transporter activity
AL536_21390	COG0800	Aldolase
AL536_21395	COG0745	RESPONSE REGULATOR receiver
AL536_21400	COG2205	protein histidine kinase activity
AL536_21405	COG2233	PERMEase
AL536_21410	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL536_21415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL536_21420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL536_21430	COG0194	GDP metabolic process
AL536_21435	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL536_21440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL536_21450	COG3263	regulation of cellular component size
AL536_21460	COG4232	protein-disulfide reductase activity
AL536_21470	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AL536_21475	COG0540	Belongs to the ATCase OTCase family
AL536_21480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL536_21495	COG1288	antiporter activity
AL536_21500	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL536_21505	COG1027	Aspartate ammonia-lyase
AL536_21510	COG3706	GGDEF domain
AL536_21515	COG3030	protein affecting phage T7 exclusion by the F plasmid
AL536_21520	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL536_21525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL536_21530	COG2205	protein histidine kinase activity
AL536_21535	COG0745	RESPONSE REGULATOR receiver
AL536_21545	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AL536_21550	COG0205	6-phosphofructokinase activity
AL536_21555	COG1494	fructose-1,6-bisphosphatase
AL536_21565	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL536_21570	COG0527	aspartate kinase activity
AL536_21570	COG0460	homoserine dehydrogenase
AL536_21575	COG0626	cystathionine gamma-synthase activity
AL536_21585	COG0281	malic enzyme
AL536_21590	COG0254	rRNA binding
AL536_21595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL536_21600	COG1609	Transcriptional regulator
AL536_21610	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AL536_21615	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL536_21620	COG1575	Belongs to the MenA family. Type 1 subfamily
AL536_21625	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL536_21635	COG0149	triose-phosphate isomerase activity
AL536_21660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL536_21665	COG0459	protein refolding
AL536_21670	COG3344	reverse transcriptase
AL536_21675	COG3344	reverse transcriptase
AL536_21685	COG1119	ATPase activity
AL536_21695	COG1285	pathogenesis
AL536_21700	COG1509	lysine 2,3-aminomutase activity
AL536_21705	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL536_21710	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL536_21715	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
AL536_21720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL536_21725	COG1053	succinate dehydrogenase
AL536_21730	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AL536_21735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL536_21740	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL536_21745	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL536_21750	COG1045	serine acetyltransferase
AL536_21755	COG1695	Transcriptional regulator
AL536_21760	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL536_21765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL536_21770	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL536_21775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL536_21785	COG0165	Argininosuccinate lyase
AL536_21785	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL536_21795	COG0678	peroxiredoxin activity
AL536_21795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL536_21805	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL536_21840	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL536_21850	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AL536_21855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL536_21865	COG0180	Tryptophanyl-tRNA synthetase
AL536_21875	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL536_21885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL536_21895	COG1012	belongs to the aldehyde dehydrogenase family
AL536_21905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL536_21910	COG3954	Phosphoribulokinase
AL536_21920	COG0429	hydrolase of the alpha beta-hydrolase fold
AL536_21930	COG0488	(ABC) transporter
AL536_21935	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL536_21945	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AL536_21950	COG1047	Peptidyl-prolyl cis-trans
AL536_21960	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL536_21965	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AL536_21970	COG3083	sulfuric ester hydrolase activity
AL536_21975	COG0557	exoribonuclease II activity
AL536_21980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL536_21985	COG0051	transcription antitermination factor activity, RNA binding
AL536_21990	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL536_21995	COG0088	Forms part of the polypeptide exit tunnel
AL536_22000	COG0089	rRNA binding
AL536_22010	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL536_22015	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL536_22030	COG0255	Belongs to the universal ribosomal protein uL29 family
AL536_22040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL536_22045	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL536_22050	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL536_22055	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL536_22060	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AL536_22065	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL536_22070	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL536_22080	COG1841	ribosomal large subunit assembly
AL536_22090	COG0201	protein transport
AL536_22105	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL536_22110	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL536_22115	COG0202	RNA polymerase activity
AL536_22120	COG0203	ribosomal protein L17
AL536_22130	COG0545	Peptidyl-prolyl cis-trans isomerase
AL536_22135	COG3061	Opacity-associated protein A
AL536_22140	COG0697	spore germination
AL536_22145	COG2153	protein acetylation
AL536_22150	COG0513	Belongs to the DEAD box helicase family
AL536_22160	COG0737	Belongs to the 5'-nucleotidase family
AL536_22165	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL536_22165	COG1648	precorrin-2 dehydrogenase activity
AL536_22170	COG0175	sulfate reduction
AL536_22175	COG2895	sulfate adenylyltransferase (ATP) activity
AL536_22180	COG0471	metal ion transport
AL536_22180	COG0490	domain, Protein
AL536_22185	COG0529	Catalyzes the synthesis of activated sulfate
AL536_22205	COG1136	(ABC) transporter
AL536_22205	COG0577	efflux transmembrane transporter activity
AL536_22220	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL536_22225	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL536_22230	COG0729	surface antigen
AL536_22240	COG2105	PFAM AIG2 family protein
AL536_22245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL536_22250	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL536_22255	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL536_22260	COG0163	prenyltransferase activity
AL536_22265	COG4143	(ABC) transporter
AL536_22270	COG1178	ABC-type Fe3 transport system permease component
AL536_22275	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AL536_22280	COG3028	Belongs to the UPF0307 family
AL536_22285	COG0312	modulator of DNA gyrase
AL536_22290	COG2239	Acts as a magnesium transporter
AL536_22295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_22305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL536_22310	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL536_22320	COG1137	ATPase activity
AL536_22325	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL536_22335	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AL536_22340	COG0517	IMP dehydrogenase activity
AL536_22340	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL536_22350	COG1127	ABC transporter
AL536_22355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL536_22360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL536_22365	COG2854	intermembrane phospholipid transfer
AL536_22370	COG3113	response to antibiotic
AL536_22375	COG5007	Belongs to the BolA IbaG family
AL536_22380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL536_22395	COG0426	domain, Protein
AL536_22395	COG1773	rubredoxin
AL536_22480	COG4628	conserved protein (DUF2132)
AL536_22550	COG4974	Belongs to the 'phage' integrase family
AL536_22695	COG3706	GGDEF domain
AL536_22710	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL536_22775	COG2965	DNA replication, synthesis of RNA primer
AL536_22810	COG0759	Could be involved in insertion of integral membrane proteins into the membrane