locus-tag	class	description
vfu_A00001	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
vfu_A00002	COG0049	tRNA binding
vfu_A00004	COG2168	tRNA wobble position uridine thiolation
vfu_A00005	COG2923	Belongs to the DsrF TusC family
vfu_A00007	COG2964	Protein conserved in bacteria
vfu_A00008	COG0545	Peptidyl-prolyl cis-trans isomerase
vfu_A00010	COG2900	Belongs to the SlyX family
vfu_A00011	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
vfu_A00012	COG0330	HflC and HflK could
vfu_A00013	COG0330	HflC and HflK could
vfu_A00014	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
vfu_A00016	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
vfu_A00017	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
vfu_A00019	COG0802	atpase or kinase
vfu_A00020	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
vfu_A00023	COG1162	GTPase activity
vfu_A00024	COG0688	phosphatidylethanolamine metabolic process
vfu_A00027	COG0490	domain, Protein
vfu_A00027	COG0471	metal ion transport
vfu_A00028	COG0840	transmembrane signaling receptor activity
vfu_A00030	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
vfu_A00031	COG4942	peptidase
vfu_A00035	COG2816	NAD+ diphosphatase activity
vfu_A00036	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
vfu_A00037	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
vfu_A00038	COG0085	RNA polymerase activity
vfu_A00039	COG0222	ribosome binding
vfu_A00040	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
vfu_A00041	COG0081	regulation of translation
vfu_A00043	COG0250	Participates in transcription elongation, termination and antitermination
vfu_A00044	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
vfu_A00046	COG1072	(Pantothenic acid kinase))
vfu_A00048	COG0812	UDP-N-acetylmuramate dehydrogenase activity
vfu_A00050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
vfu_A00056	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
vfu_A00058	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
vfu_A00059	COG3118	belongs to the thioredoxin family
vfu_A00060	COG0513	Belongs to the DEAD box helicase family
vfu_A00061	COG0248	Ppx GppA phosphatase
vfu_A00062	COG2205	protein histidine kinase activity
vfu_A00062	COG2198	Histidine kinase
vfu_A00062	COG0784	Response regulator, receiver
vfu_A00062	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vfu_A00063	COG2814	Major facilitator Superfamily
vfu_A00066	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
vfu_A00067	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
vfu_A00068	COG0511	ligase activity, forming carbon-carbon bonds
vfu_A00069	COG0439	Biotin carboxylase
vfu_A00070	COG2264	protein methyltransferase activity
vfu_A00071	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
vfu_A00072	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
vfu_A00073	COG0840	transmembrane signaling receptor activity
vfu_A00076	COG2207	Transcriptional regulator
vfu_A00077	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
vfu_A00077	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
vfu_A00077	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
vfu_A00079	COG1940	carbohydrate kinase activity
vfu_A00080	COG0789	Transcriptional regulator
vfu_A00082	COG0138	bifunctional purine biosynthesis protein purh
vfu_A00083	COG0151	Belongs to the GarS family
vfu_A00085	COG0776	regulation of translation
vfu_A00086	COG1253	flavin adenine dinucleotide binding
vfu_A00087	COG0668	transmembrane transport
vfu_A00088	COG3068	Protein conserved in bacteria
vfu_A00089	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
vfu_A00090	COG1573	uracil-dna glycosylase
vfu_A00094	COG0741	lytic transglycosylase activity
vfu_A00097	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
vfu_A00098	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
vfu_A00099	COG3562	capsule polysaccharide
vfu_A00100	COG0438	transferase activity, transferring glycosyl groups
vfu_A00101	COG0438	transferase activity, transferring glycosyl groups
vfu_A00103	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
vfu_A00106	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_A00108	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_A00110	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
vfu_A00114	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
vfu_A00126	COG0489	protein tyrosine kinase activity
vfu_A00126	COG3206	protein involved in exopolysaccharide biosynthesis
vfu_A00132	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
vfu_A00133	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
vfu_A00135	COG1560	Kdo2-lipid A biosynthetic process
vfu_A00138	COG0438	transferase activity, transferring glycosyl groups
vfu_A00141	COG0859	PFAM glycosyl transferase family 9
vfu_A00142	COG1519	Transferase
vfu_A00145	COG0859	PFAM glycosyl transferase family 9
vfu_A00146	COG0463	Glycosyl transferase, family 2
vfu_A00147	COG0438	transferase activity, transferring glycosyl groups
vfu_A00148	COG0438	transferase activity, transferring glycosyl groups
vfu_A00149	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
vfu_A00152	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
vfu_A00154	COG0267	Belongs to the bacterial ribosomal protein bL33 family
vfu_A00159	COG1309	transcriptional regulator
vfu_A00160	COG1560	Kdo2-lipid A biosynthetic process
vfu_A00161	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
vfu_A00163	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
vfu_A00164	COG1561	YicC-like family, N-terminal region
vfu_A00168	COG2003	Belongs to the UPF0758 family
vfu_A00178	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
vfu_A00184	COG2963	transposase activity
vfu_A00185	COG5002	protein histidine kinase activity
vfu_A00188	COG3335	DDE superfamily endonuclease
vfu_A00193	COG2217	Heavy metal translocating P-type atpase
vfu_A00205	COG0328	RNA-DNA hybrid ribonuclease activity
vfu_A00213	COG4607	ABC-type enterochelin transport system periplasmic component
vfu_A00214	COG1120	ATPase activity
vfu_A00215	COG4774	siderophore transport
vfu_A00216	COG1132	(ABC) transporter
vfu_A00219	COG0514	ATP-dependent DNA helicase (RecQ)
vfu_A00220	COG2962	Rard protein
vfu_A00222	COG1280	lysine exporter protein (LysE YggA)
vfu_A00223	COG0405	Gamma-glutamyltransferase
vfu_A00224	COG0210	DNA helicase
vfu_A00232	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
vfu_A00233	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
vfu_A00236	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
vfu_A00237	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
vfu_A00244	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
vfu_A00246	COG0747	negative chemotaxis
vfu_A00247	COG4172	Belongs to the ABC transporter superfamily
vfu_A00251	COG1309	transcriptional regulator
vfu_A00252	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
vfu_A00253	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
vfu_A00254	COG2960	long-chain fatty acid transporting porin activity
vfu_A00255	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
vfu_A00256	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
vfu_A00258	COG0583	DNA-binding transcription factor activity
vfu_A00261	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
vfu_A00263	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
vfu_A00264	COG0408	coproporphyrinogen oxidase activity
vfu_A00267	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
vfu_A00268	COG0551	DNA topoisomerase type I activity
vfu_A00269	COG2922	Belongs to the Smg family
vfu_A00270	COG0758	DNA mediated transformation
vfu_A00274	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
vfu_A00274	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
vfu_A00275	COG0569	domain protein
vfu_A00276	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
vfu_A00278	COG1272	protein, Hemolysin III
vfu_A00279	COG4326	sporulation control protein
vfu_A00281	COG3084	Protein conserved in bacteria
vfu_A00283	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
vfu_A00284	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
vfu_A00285	COG0204	Acyl-transferase
vfu_A00286	COG0606	chelatase, subunit chli
vfu_A00289	COG3978	acetolactate synthase activity
vfu_A00290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
vfu_A00293	COG0604	alcohol dehydrogenase
vfu_A00297	COG2199	diguanylate cyclase activity
vfu_A00297	COG2203	Gaf domain
vfu_A00298	COG2199	diguanylate cyclase activity
vfu_A00302	COG2119	membrane
vfu_A00303	COG0752	glycyl-tRNA synthetase alpha subunit
vfu_A00304	COG0751	glycine-tRNA ligase activity
vfu_A00305	COG3977	Valine--pyruvate aminotransferase
vfu_A00306	COG0071	Belongs to the small heat shock protein (HSP20) family
vfu_A00310	COG0187	DNA topoisomerase II activity
vfu_A00312	COG0592	DNA-directed DNA polymerase activity
vfu_A00313	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
vfu_A00316	COG1126	abc transporter atp-binding protein
vfu_A00317	COG0230	Belongs to the bacterial ribosomal protein bL34 family
vfu_A00319	COG0706	membrane insertase activity
vfu_A00324	COG4869	propanediol catabolic process
vfu_A00325	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
vfu_A00326	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
vfu_A00327	COG1882	Formate acetyltransferase
vfu_A00330	COG1012	belongs to the aldehyde dehydrogenase family
vfu_A00330	COG1454	alcohol dehydrogenase
vfu_A00331	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
vfu_A00332	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
vfu_A00333	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
vfu_A00338	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
vfu_A00339	COG0445	tRNA wobble uridine modification
vfu_A00340	COG0357	Ribosomal RNA small subunit methyltransferase G
vfu_A00341	COG1192	Involved in chromosome partitioning
vfu_A00342	COG1475	DNA binding
vfu_A00343	COG3312	ion transport
vfu_A00344	COG0356	it plays a direct role in the translocation of protons across the membrane
vfu_A00346	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
vfu_A00347	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
vfu_A00349	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
vfu_A00351	COG0355	proton-transporting ATP synthase activity, rotational mechanism
vfu_A00353	COG0765	amino acid transport
vfu_A00355	COG2814	Major facilitator Superfamily
vfu_A00356	COG0583	DNA-binding transcription factor activity
vfu_A00357	COG0183	Belongs to the thiolase family
vfu_A00359	COG1739	Uncharacterized protein family UPF0029
vfu_A00360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
vfu_A00366	COG2132	Multicopper oxidase
vfu_A00367	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
vfu_A00368	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
vfu_A00370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
vfu_A00372	COG2022	thiamine diphosphate biosynthetic process
vfu_A00373	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
vfu_A00375	COG4175	Glycine betaine
vfu_A00378	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
vfu_A00382	COG0006	proline dipeptidase activity
vfu_A00382	COG0006	proline dipeptidase activity
vfu_A00386	COG1522	sequence-specific DNA binding
vfu_A00387	COG5002	protein histidine kinase activity
vfu_A00387	COG5001	Diguanylate cyclase
vfu_A00388	COG0742	ribosomal rna small subunit methyltransferase
vfu_A00390	COG0697	spore germination
vfu_A00391	COG0589	response to stress
vfu_A00392	COG1528	Iron-storage protein
vfu_A00394	COG2081	HI0933 family
vfu_A00395	COG1172	Belongs to the binding-protein-dependent transport system permease family
vfu_A00396	COG1172	Belongs to the binding-protein-dependent transport system permease family
vfu_A00397	COG1129	ABC transporter
vfu_A00398	COG1879	ABC-type sugar transport system periplasmic component
vfu_A00399	COG1172	Belongs to the binding-protein-dependent transport system permease family
vfu_A00400	COG1129	ABC transporter
vfu_A00401	COG1879	ABC-type sugar transport system periplasmic component
vfu_A00402	COG1069	ribulokinase activity
vfu_A00404	COG2160	L-arabinose isomerase activity
vfu_A00409	COG1322	Protein conserved in bacteria
vfu_A00410	COG2226	methyltransferase
vfu_A00411	COG2226	methyltransferase
vfu_A00412	COG2226	methyltransferase
vfu_A00413	COG3165	ubiquinone biosynthetic process from chorismate
vfu_A00416	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
vfu_A00417	COG0805	protein transport
vfu_A00420	COG0084	hydrolase, TatD family'
vfu_A00423	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
vfu_A00423	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
vfu_A00424	COG0218	Necessary for normal cell division and for the maintenance of normal septation
vfu_A00429	COG0635	Involved in the biosynthesis of porphyrin-containing compound
vfu_A00430	COG3071	HemY protein
vfu_A00431	COG2959	enzyme of heme biosynthesis
vfu_A00435	COG3072	Adenylate cyclase
vfu_A00438	COG0019	diaminopimelate decarboxylase activity
vfu_A00441	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
vfu_A00442	COG1011	Hydrolase
vfu_A00443	COG2200	EAL domain
vfu_A00443	COG2199	diguanylate cyclase activity
vfu_A00443	COG3287	FIST C domain
vfu_A00447	COG0561	phosphatase activity
vfu_A00448	COG2267	carboxylic ester hydrolase activity
vfu_A00449	COG1280	lysine exporter protein (LysE YggA)
vfu_A00450	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
vfu_A00451	COG0640	Transcriptional regulator
vfu_A00452	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
vfu_A00455	COG0783	Belongs to the Dps family
vfu_A00464	COG2095	MarC family integral membrane protein
vfu_A00466	COG0742	ribosomal rna small subunit methyltransferase
vfu_A00467	COG0552	protein localization to endoplasmic reticulum
vfu_A00468	COG2884	Cell division ATP-binding protein ftsE
vfu_A00469	COG2177	Part of the ABC transporter FtsEX involved in
vfu_A00470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
vfu_A00471	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
vfu_A00472	COG0705	Rhomboid family
vfu_A00473	COG1580	Controls the rotational direction of flagella during chemotaxis
vfu_A00474	COG3161	chorismate lyase activity
vfu_A00475	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
vfu_A00476	COG2937	Belongs to the GPAT DAPAT family
vfu_A00478	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
vfu_A00479	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
vfu_A00481	COG0534	Mate efflux family protein
vfu_A00485	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
vfu_A00488	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
vfu_A00492	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
vfu_A00493	COG5001	Diguanylate cyclase
vfu_A00493	COG3300	MHYT domain
vfu_A00494	COG2204	response regulator
vfu_A00495	COG3852	Histidine kinase
vfu_A00498	COG0174	glutamine synthetase
vfu_A00503	COG1490	D-aminoacyl-tRNA deacylase activity
vfu_A00504	COG0456	acetyltransferase
vfu_A00505	COG2982	Protein involved in outer membrane biogenesis
vfu_A00506	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
vfu_A00508	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
vfu_A00509	COG3031	protein transport across the cell outer membrane
vfu_A00511	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
vfu_A00512	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
vfu_A00513	COG1459	type II secretion system
vfu_A00514	COG2165	general secretion pathway protein
vfu_A00515	COG2165	general secretion pathway protein
vfu_A00516	COG2165	general secretion pathway protein
vfu_A00517	COG4795	General secretion pathway protein
vfu_A00518	COG3156	type II secretion system protein K
vfu_A00519	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
vfu_A00520	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
vfu_A00522	COG1218	3'(2'),5'-bisphosphate nucleotidase
vfu_A00523	COG0494	nUDIX hydrolase
vfu_A00524	COG0316	Belongs to the HesB IscA family
vfu_A00524	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
vfu_A00525	COG1040	competence protein
vfu_A00526	COG0596	Alpha beta hydrolase
vfu_A00528	COG2183	response to ionizing radiation
vfu_A00529	COG2183	response to ionizing radiation
vfu_A00531	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
vfu_A00532	COG1609	Transcriptional regulator
vfu_A00533	COG0129	dihydroxy-acid dehydratase activity
vfu_A00534	COG3265	gluconokinase activity
vfu_A00535	COG2610	gluconate transmembrane transporter activity
vfu_A00536	COG0800	Aldolase
vfu_A00538	COG0745	RESPONSE REGULATOR receiver
vfu_A00539	COG2205	protein histidine kinase activity
vfu_A00541	COG2233	PERMEase
vfu_A00542	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
vfu_A00543	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
vfu_A00544	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
vfu_A00546	COG0194	GDP metabolic process
vfu_A00548	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
vfu_A00549	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
vfu_A00551	COG3263	regulation of cellular component size
vfu_A00554	COG4232	protein-disulfide reductase activity
vfu_A00558	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
vfu_A00559	COG0540	Belongs to the ATCase OTCase family
vfu_A00561	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
vfu_A00565	COG1288	antiporter activity
vfu_A00566	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
vfu_A00567	COG1027	Aspartate ammonia-lyase
vfu_A00568	COG3706	GGDEF domain
vfu_A00570	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
vfu_A00571	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
vfu_A00572	COG2205	protein histidine kinase activity
vfu_A00573	COG0745	RESPONSE REGULATOR receiver
vfu_A00575	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
vfu_A00576	COG0205	6-phosphofructokinase activity
vfu_A00577	COG1494	fructose-1,6-bisphosphatase
vfu_A00580	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
vfu_A00581	COG0527	aspartate kinase activity
vfu_A00581	COG0460	homoserine dehydrogenase
vfu_A00582	COG0626	cystathionine gamma-synthase activity
vfu_A00584	COG0281	malic enzyme
vfu_A00586	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
vfu_A00587	COG1609	Transcriptional regulator
vfu_A00589	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
vfu_A00591	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
vfu_A00592	COG1575	Belongs to the MenA family. Type 1 subfamily
vfu_A00593	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
vfu_A00594	COG0534	Mate efflux family protein
vfu_A00596	COG0149	triose-phosphate isomerase activity
vfu_A00601	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
vfu_A00602	COG0459	protein refolding
vfu_A00603	COG1119	ATPase activity
vfu_A00605	COG1285	pathogenesis
vfu_A00606	COG1509	lysine 2,3-aminomutase activity
vfu_A00607	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
vfu_A00608	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
vfu_A00609	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
vfu_A00610	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
vfu_A00611	COG1053	succinate dehydrogenase
vfu_A00613	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
vfu_A00614	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
vfu_A00615	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
vfu_A00616	COG1045	serine acetyltransferase
vfu_A00618	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
vfu_A00619	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
vfu_A00620	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
vfu_A00621	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
vfu_A00623	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
vfu_A00623	COG0165	Argininosuccinate lyase
vfu_A00624	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
vfu_A00624	COG0165	Argininosuccinate lyase
vfu_A00626	COG0678	peroxiredoxin activity
vfu_A00626	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
vfu_A00628	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
vfu_A00635	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
vfu_A00637	COG0338	D12 class N6 adenine-specific DNA methyltransferase
vfu_A00638	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
vfu_A00640	COG0180	Tryptophanyl-tRNA synthetase
vfu_A00644	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
vfu_A00646	COG1012	belongs to the aldehyde dehydrogenase family
vfu_A00648	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
vfu_A00649	COG3954	Phosphoribulokinase
vfu_A00651	COG0429	hydrolase of the alpha beta-hydrolase fold
vfu_A00653	COG0488	(ABC) transporter
vfu_A00654	COG2249	NAD(P)H dehydrogenase (quinone) activity
vfu_A00657	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
vfu_A00658	COG1047	Peptidyl-prolyl cis-trans
vfu_A00660	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
vfu_A00661	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
vfu_A00662	COG3083	sulfuric ester hydrolase activity
vfu_A00663	COG0557	exoribonuclease II activity
vfu_A00664	COG0557	exoribonuclease II activity
vfu_A00665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
vfu_A00666	COG0051	transcription antitermination factor activity, RNA binding
vfu_A00667	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
vfu_A00668	COG0088	Forms part of the polypeptide exit tunnel
vfu_A00669	COG0089	rRNA binding
vfu_A00671	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
vfu_A00672	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
vfu_A00674	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
vfu_A00675	COG0255	Belongs to the universal ribosomal protein uL29 family
vfu_A00676	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
vfu_A00677	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
vfu_A00678	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
vfu_A00679	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
vfu_A00680	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
vfu_A00681	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
vfu_A00682	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
vfu_A00683	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
vfu_A00685	COG1841	ribosomal large subunit assembly
vfu_A00687	COG0201	protein transport
vfu_A00689	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
vfu_A00690	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
vfu_A00691	COG0202	RNA polymerase activity
vfu_A00694	COG0545	Peptidyl-prolyl cis-trans isomerase
vfu_A00695	COG3061	Opacity-associated protein A
vfu_A00696	COG2153	protein acetylation
vfu_A00697	COG0513	Belongs to the DEAD box helicase family
vfu_A00699	COG0737	Belongs to the 5'-nucleotidase family
vfu_A00700	COG1648	precorrin-2 dehydrogenase activity
vfu_A00700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
vfu_A00701	COG0175	sulfate reduction
vfu_A00702	COG0175	sulfate reduction
vfu_A00703	COG2895	sulfate adenylyltransferase (ATP) activity
vfu_A00704	COG3273	potassium ion transport
vfu_A00704	COG0471	metal ion transport
vfu_A00705	COG0529	Catalyzes the synthesis of activated sulfate
vfu_A00710	COG0577	efflux transmembrane transporter activity
vfu_A00710	COG1136	(ABC) transporter
vfu_A00713	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
vfu_A00714	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
vfu_A00715	COG0729	surface antigen
vfu_A00717	COG2105	PFAM AIG2 family protein
vfu_A00719	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
vfu_A00720	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
vfu_A00721	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
vfu_A00722	COG0163	prenyltransferase activity
vfu_A00723	COG4143	(ABC) transporter
vfu_A00724	COG1178	ABC-type Fe3 transport system permease component
vfu_A00725	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
vfu_A00726	COG3028	Belongs to the UPF0307 family
vfu_A00727	COG0312	modulator of DNA gyrase
vfu_A00728	COG2239	Acts as a magnesium transporter
vfu_A00729	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
vfu_A00731	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
vfu_A00732	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
vfu_A00734	COG1137	ATPase activity
vfu_A00735	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
vfu_A00737	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
vfu_A00738	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
vfu_A00738	COG0517	IMP dehydrogenase activity
vfu_A00740	COG1127	ABC transporter
vfu_A00741	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
vfu_A00742	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
vfu_A00743	COG2854	intermembrane phospholipid transfer
vfu_A00744	COG3113	response to antibiotic
vfu_A00745	COG5007	Belongs to the BolA IbaG family
vfu_A00747	COG0204	Acyl-transferase
vfu_A00748	COG0251	oxidation-reduction process
vfu_A00749	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
vfu_A00750	COG0540	Belongs to the ATCase OTCase family
vfu_A00751	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
vfu_A00752	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
vfu_A00753	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
vfu_A00755	COG0564	pseudouridine synthase activity
vfu_A00756	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
vfu_A00757	COG0525	valine-tRNA ligase activity
vfu_A00758	COG0525	valine-tRNA ligase activity
vfu_A00759	COG0525	valine-tRNA ligase activity
vfu_A00761	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
vfu_A00762	COG0795	lipopolysaccharide-transporting ATPase activity
vfu_A00763	COG0795	lipopolysaccharide-transporting ATPase activity
vfu_A00765	COG3706	GGDEF domain
vfu_A00779	COG2916	Histone family protein nucleoid-structuring protein H-NS
vfu_A00788	COG0583	DNA-binding transcription factor activity
vfu_A00790	COG0840	transmembrane signaling receptor activity
vfu_A00800	COG3437	response regulator, receiver
vfu_A00805	COG0066	3-isopropylmalate dehydratase activity
vfu_A00806	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
vfu_A00807	COG0473	3-isopropylmalate dehydrogenase activity
vfu_A00808	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
vfu_A00812	COG0583	DNA-binding transcription factor activity
vfu_A00813	COG1022	Amp-dependent synthetase and ligase
vfu_A00814	COG0028	Belongs to the TPP enzyme family
vfu_A00815	COG0440	acetolactate synthase activity
vfu_A00816	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
vfu_A00817	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
vfu_A00818	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
vfu_A00819	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
vfu_A00821	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
vfu_A00822	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
vfu_A00826	COG0354	folic acid binding
vfu_A00827	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
vfu_A00829	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
vfu_A00830	COG1595	DNA-templated transcription, initiation
vfu_A00833	COG3086	response to oxidative stress
vfu_A00834	COG0481	GTPase activity
vfu_A00835	COG0681	Belongs to the peptidase S26 family
vfu_A00837	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
vfu_A00838	COG1381	Involved in DNA repair and RecF pathway recombination
vfu_A00839	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
vfu_A00842	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
vfu_A00843	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
vfu_A00844	COG3956	TIGRFAM MazG family protein
vfu_A00845	COG0504	CTP synthase activity
vfu_A00846	COG0148	phosphopyruvate hydratase activity
vfu_A00847	COG0617	tRNA 3'-terminal CCA addition
vfu_A00848	COG3409	Peptidoglycan-binding domain 1 protein
vfu_A00848	COG3267	Type II secretory pathway component ExeA
vfu_A00850	COG4991	sh3 domain protein
vfu_A00851	COG0306	phosphate transporter
vfu_A00852	COG1392	Phosphate transport regulator
vfu_A00853	COG3025	triphosphatase activity
vfu_A00854	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
vfu_A00856	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
vfu_A00857	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
vfu_A00858	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
vfu_A00858	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
vfu_A00859	COG1538	Outer membrane efflux protein
vfu_A00860	COG0494	nUDIX hydrolase
vfu_A00861	COG3151	Protein conserved in bacteria
vfu_A00863	COG3150	esterase
vfu_A00864	COG0187	DNA topoisomerase II activity
vfu_A00866	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
vfu_A00867	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
vfu_A00868	COG0237	dephospho-CoA kinase activity
vfu_A00870	COG1459	type II secretion system
vfu_A00871	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
vfu_A00875	COG0716	FMN binding
vfu_A00876	COG4974	Belongs to the 'phage' integrase family
vfu_A00877	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
vfu_A00878	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
vfu_A00879	COG2186	Transcriptional regulator
vfu_A00880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
vfu_A00881	COG0508	dehydrogenase complex catalyzes the overall conversion of
vfu_A00882	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
vfu_A00886	COG0288	reversible hydration of carbon dioxide
vfu_A00887	COG1131	(ABC) transporter
vfu_A00888	COG0842	Transport permease protein
vfu_A00889	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
vfu_A00890	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
vfu_A00891	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
vfu_A00893	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
vfu_A00894	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
vfu_A00895	COG1489	DNA binding
vfu_A00896	COG1643	Atp-dependent helicase
vfu_A00897	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
vfu_A00898	COG1752	Esterase of the alpha-beta hydrolase superfamily
vfu_A00899	COG1049	propionate catabolic process, 2-methylcitrate cycle
vfu_A00900	COG3112	Uncharacterised protein family (UPF0231)
vfu_A00901	COG0347	Belongs to the P(II) protein family
vfu_A00902	COG0004	ammonium transporteR
vfu_A00903	COG1840	ABC-type Fe3 transport system, periplasmic component
vfu_A00905	COG3842	ATPase activity
vfu_A00906	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
vfu_A00909	COG2971	BadF BadG BcrA BcrD
vfu_A00911	COG4608	Belongs to the ABC transporter superfamily
vfu_A00912	COG0444	Belongs to the ABC transporter superfamily
vfu_A00913	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
vfu_A00915	COG0747	negative chemotaxis
vfu_A00916	COG0784	Response regulator, receiver
vfu_A00916	COG2205	protein histidine kinase activity
vfu_A00917	COG2813	Specifically methylates the guanine in position
vfu_A00918	COG0628	permease
vfu_A00920	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
vfu_A00921	COG0316	Belongs to the HesB IscA family
vfu_A00924	COG0739	heme binding
vfu_A00925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
vfu_A00927	COG2027	D-alanyl-D-alanine carboxypeptidase
vfu_A00928	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
vfu_A00930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
vfu_A00931	COG1534	Rna-binding protein
vfu_A00933	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
vfu_A00934	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
vfu_A00935	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
vfu_A00936	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
vfu_A00937	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
vfu_A00938	COG0779	Required for maturation of 30S ribosomal subunits
vfu_A00939	COG0195	Participates in both transcription termination and antitermination
vfu_A00940	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
vfu_A00941	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
vfu_A00942	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
vfu_A00943	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
vfu_A00947	COG0534	Mate efflux family protein
vfu_A00952	COG3153	acetyltransferase
vfu_A00956	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
vfu_A00957	COG0513	Belongs to the DEAD box helicase family
vfu_A00958	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
vfu_A00961	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
vfu_A00962	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
vfu_A00963	COG2204	response regulator
vfu_A00966	COG0667	Aldo Keto reductase
vfu_A00968	COG3066	DNA modification
vfu_A00971	COG0730	response to heat
vfu_A00973	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
vfu_A00974	COG1283	sodium-dependent phosphate transmembrane transporter activity
vfu_A00975	COG0583	DNA-binding transcription factor activity
vfu_A00977	COG0640	Transcriptional regulator
vfu_A00979	COG0728	peptidoglycan biosynthetic process
vfu_A00980	COG0196	riboflavin kinase activity
vfu_A00981	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
vfu_A00982	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
vfu_A00983	COG1047	Peptidyl-prolyl cis-trans
vfu_A00984	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
vfu_A00985	COG1966	Carbon starvation protein
vfu_A00988	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
vfu_A00989	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
vfu_A00991	COG3279	Response regulator of the LytR AlgR family
vfu_A00992	COG3275	phosphorelay sensor kinase activity
vfu_A00993	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
vfu_A00994	COG0287	Prephenate dehydrogenase
vfu_A00994	COG1605	Chorismate mutase
vfu_A00996	COG0488	(ABC) transporter
vfu_A00997	COG0488	(ABC) transporter
vfu_A01000	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
vfu_A01001	COG5001	Diguanylate cyclase
vfu_A01002	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
vfu_A01003	COG0077	Prephenate dehydratase
vfu_A01003	COG1605	Chorismate mutase
vfu_A01004	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
vfu_A01005	COG0741	lytic transglycosylase activity
vfu_A01006	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
vfu_A01007	COG0564	pseudouridine synthase activity
vfu_A01009	COG0542	response to heat
vfu_A01011	COG0590	tRNA wobble adenosine to inosine editing
vfu_A01012	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
vfu_A01014	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
vfu_A01024	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
vfu_A01027	COG0271	Belongs to the BolA IbaG family
vfu_A01028	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
vfu_A01029	COG1805	sodium ion transport
vfu_A01031	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
vfu_A01032	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
vfu_A01033	COG2871	sodium ion transport
vfu_A01034	COG1477	protein flavinylation
vfu_A01037	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
vfu_A01039	COG3706	GGDEF domain
vfu_A01039	COG4251	negative regulation of phosphorylation
vfu_A01039	COG2203	Gaf domain
vfu_A01039	COG5001	Diguanylate cyclase
vfu_A01040	COG0733	neurotransmitter:sodium symporter activity
vfu_A01042	COG0189	ligase activity
vfu_A01043	COG0189	ligase activity
vfu_A01043	COG4067	protein conserved in archaea
vfu_A01044	COG2195	Cleaves the N-terminal amino acid of tripeptides
vfu_A01046	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vfu_A01047	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
vfu_A01049	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
vfu_A01051	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
vfu_A01052	COG2252	PERMEase
vfu_A01053	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
vfu_A01057	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
vfu_A01058	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
vfu_A01059	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
vfu_A01059	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
vfu_A01063	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
vfu_A01064	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
vfu_A01065	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
vfu_A01067	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
vfu_A01068	COG0024	Methionine aminopeptidase
vfu_A01072	COG0233	cytoplasmic translational termination
vfu_A01073	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
vfu_A01074	COG0575	Belongs to the CDS family
vfu_A01075	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
vfu_A01076	COG0750	zinc metalloprotease
vfu_A01078	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
vfu_A01079	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
vfu_A01080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
vfu_A01083	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
vfu_A01084	COG0587	DNA-directed DNA polymerase activity
vfu_A01085	COG0825	malonyl-CoA metabolic process
vfu_A01086	COG0037	tRNA processing
vfu_A01088	COG0347	Belongs to the P(II) protein family
vfu_A01090	COG1388	LysM domain
vfu_A01090	COG0741	lytic transglycosylase activity
vfu_A01091	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
vfu_A01092	COG2226	methyltransferase
vfu_A01093	COG0328	RNA-DNA hybrid ribonuclease activity
vfu_A01094	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
vfu_A01096	COG1960	acyl-CoA dehydrogenase activity
vfu_A01097	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
vfu_A01098	COG0121	glutamine amidotransferase
vfu_A01099	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
vfu_A01100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
vfu_A01101	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
vfu_A01102	COG1187	pseudouridine synthase activity
vfu_A01103	COG2840	Smr protein MutS2
vfu_A01108	COG2217	Heavy metal translocating P-type atpase
vfu_A01108	COG2608	mercury ion transmembrane transporter activity
vfu_A01109	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
vfu_A01116	COG2747	anti-sigma28 factor FlgM
vfu_A01118	COG0835	chemotaxis
vfu_A01118	COG0784	Response regulator, receiver
vfu_A01119	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
vfu_A01121	COG1815	bacterial-type flagellum-dependent cell motility
vfu_A01122	COG1558	bacterial-type flagellum-dependent cell motility
vfu_A01123	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
vfu_A01124	COG1749	Flagellar hook protein flgE
vfu_A01125	COG4787	bacterial-type flagellum-dependent cell motility
vfu_A01126	COG4786	Flagellar basal body rod
vfu_A01127	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
vfu_A01128	COG1706	bacterial-type flagellum-dependent cell motility
vfu_A01129	COG3951	Flagellar rod assembly protein muramidase FlgJ
vfu_A01129	COG1705	Flagellar rod assembly protein muramidase FlgJ
vfu_A01131	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
vfu_A01132	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
vfu_A01136	COG0193	aminoacyl-tRNA hydrolase activity
vfu_A01137	COG0193	aminoacyl-tRNA hydrolase activity
vfu_A01138	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
vfu_A01140	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
vfu_A01141	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
vfu_A01143	COG2890	protein-(glutamine-N5) methyltransferase activity
vfu_A01144	COG3094	Invasion gene expression up-regulator, SirB
vfu_A01145	COG2912	Transglutaminase-like superfamily
vfu_A01148	COG0737	Belongs to the 5'-nucleotidase family
vfu_A01149	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
vfu_A01150	COG2233	PERMEase
vfu_A01154	COG1393	Belongs to the ArsC family
vfu_A01155	COG4783	chaperone-mediated protein folding
vfu_A01159	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
vfu_A01160	COG2716	regulation of RNA biosynthetic process
vfu_A01161	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
vfu_A01162	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
vfu_A01164	COG1876	peptidase activity
vfu_A01165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
vfu_A01166	COG1393	Belongs to the ArsC family
vfu_A01168	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
vfu_A01169	COG1085	galactose-1-phosphate uridylyltransferase
vfu_A01170	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
vfu_A01173	COG0516	GMP reductase activity
vfu_A01173	COG0517	IMP dehydrogenase activity
vfu_A01177	COG2837	iron assimilation
vfu_A01181	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
vfu_A01182	COG1334	flagellar protein FlaG
vfu_A01183	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
vfu_A01185	COG1516	flagellar protein fliS
vfu_A01186	COG2204	response regulator
vfu_A01187	COG4191	Histidine kinase
vfu_A01188	COG2204	response regulator
vfu_A01189	COG1677	Flagellar hook-basal body complex protein FliE
vfu_A01191	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
vfu_A01201	COG1987	bacterial-type flagellum assembly
vfu_A01205	COG2890	protein-(glutamine-N5) methyltransferase activity
vfu_A01206	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
vfu_A01207	COG2860	membrane
vfu_A01209	COG3101	peptidyl-lysine hydroxylation
vfu_A01212	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
vfu_A01212	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
vfu_A01213	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
vfu_A01215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
vfu_A01216	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
vfu_A01217	COG0735	belongs to the Fur family
vfu_A01219	COG0583	DNA-binding transcription factor activity
vfu_A01220	COG1380	Effector of murein hydrolase LrgA
vfu_A01221	COG1346	cytolysis
vfu_A01224	COG0596	Alpha beta hydrolase
vfu_A01225	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
vfu_A01226	COG0033	Phosphoglucomutase
vfu_A01228	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
vfu_A01230	COG2009	succinate dehydrogenase
vfu_A01231	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
vfu_A01232	COG1053	succinate dehydrogenase
vfu_A01234	COG0567	Dehydrogenase, E1 component
vfu_A01235	COG0508	dehydrogenase complex catalyzes the overall conversion of
vfu_A01238	COG1108	ABC-type Mn2 Zn2 transport systems permease components
vfu_A01239	COG1121	(ABC) transporter
vfu_A01240	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
vfu_A01241	COG2207	Transcriptional regulator
vfu_A01242	COG1918	ferrous iron import across plasma membrane
vfu_A01247	COG3102	Protein conserved in bacteria
vfu_A01249	COG2062	phosphohistidine phosphatase, SixA
vfu_A01252	COG0455	bacterial-type flagellum organization
vfu_A01255	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
vfu_A01256	COG0643	Histidine kinase
vfu_A01256	COG2198	Histidine kinase
vfu_A01258	COG1192	Involved in chromosome partitioning
vfu_A01260	COG0835	chemotaxis
vfu_A01262	COG4133	protoheme IX ABC transporter activity
vfu_A01263	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
vfu_A01264	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
vfu_A01265	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
vfu_A01266	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
vfu_A01267	COG1138	Cytochrome C-type biogenesis protein
vfu_A01268	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
vfu_A01271	COG2853	Lipoprotein
vfu_A01275	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
vfu_A01276	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
vfu_A01280	COG0123	including yeast histone deacetylase and acetoin utilization protein
vfu_A01282	COG1448	Aminotransferase
vfu_A01286	COG2814	Major facilitator Superfamily
vfu_A01288	COG3083	sulfuric ester hydrolase activity
vfu_A01290	COG3081	Nucleoid-associated protein
vfu_A01292	COG1757	Na H antiporter
vfu_A01293	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
vfu_A01294	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
vfu_A01295	COG2095	MarC family integral membrane protein
vfu_A01296	COG1454	alcohol dehydrogenase
vfu_A01296	COG1012	belongs to the aldehyde dehydrogenase family
vfu_A01298	COG0659	secondary active sulfate transmembrane transporter activity
vfu_A01300	COG1530	ribonuclease E activity
vfu_A01301	COG0564	pseudouridine synthase activity
vfu_A01302	COG0424	maF-like protein
vfu_A01303	COG1399	metal-binding, possibly nucleic acid-binding protein
vfu_A01305	COG0416	fatty acid biosynthetic process
vfu_A01306	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
vfu_A01310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
vfu_A01311	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
vfu_A01312	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
vfu_A01313	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
vfu_A01314	COG0470	DNA polymerase III
vfu_A01315	COG0084	hydrolase, TatD family'
vfu_A01317	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
vfu_A01317	COG2190	(PTS) system
vfu_A01317	COG1263	PTS System
vfu_A01319	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
vfu_A01319	COG1263	PTS System
vfu_A01321	COG0733	neurotransmitter:sodium symporter activity
vfu_A01323	COG4667	esterase of the alpha-beta hydrolase superfamily
vfu_A01324	COG0469	pyruvate kinase activity
vfu_A01325	COG1940	carbohydrate kinase activity
vfu_A01326	COG0835	chemotaxis
vfu_A01326	COG0784	Response regulator, receiver
vfu_A01327	COG0587	DNA-directed DNA polymerase activity
vfu_A01330	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_A01331	COG0616	signal peptide processing
vfu_A01335	COG0232	Belongs to the dGTPase family. Type 2 subfamily
vfu_A01336	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
vfu_A01337	COG0436	Aminotransferase
vfu_A01339	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
vfu_A01341	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
vfu_A01342	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
vfu_A01343	COG1441	menaquinone biosynthetic process
vfu_A01345	COG2855	membrane
vfu_A01346	COG0477	Major facilitator Superfamily
vfu_A01350	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
vfu_A01351	COG0741	lytic transglycosylase activity
vfu_A01351	COG1388	LysM domain
vfu_A01356	COG1815	bacterial-type flagellum-dependent cell motility
vfu_A01357	COG1558	bacterial-type flagellum-dependent cell motility
vfu_A01358	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
vfu_A01359	COG1749	Flagellar hook protein flgE
vfu_A01361	COG4786	Flagellar basal body rod
vfu_A01362	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
vfu_A01363	COG1706	bacterial-type flagellum-dependent cell motility
vfu_A01365	COG4786	Flagellar basal body rod
vfu_A01365	COG1256	bacterial-type flagellum assembly
vfu_A01372	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
vfu_A01382	COG3015	lipoprotein NlpE involved in copper resistance
vfu_A01384	COG1360	Flagellar Motor Protein
vfu_A01385	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
vfu_A01386	COG1191	sigma factor activity
vfu_A01387	COG1580	Controls the rotational direction of flagella during chemotaxis
vfu_A01391	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
vfu_A01392	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
vfu_A01395	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
vfu_A01397	COG1987	bacterial-type flagellum assembly
vfu_A01402	COG3047	cAMP biosynthetic process
vfu_A01402	COG2885	chlorophyll binding
vfu_A01403	COG2204	response regulator
vfu_A01411	COG1522	sequence-specific DNA binding
vfu_A01413	COG1946	Acyl-CoA thioesterase
vfu_A01415	COG3126	Type III secretion system lipoprotein chaperone (YscW)
vfu_A01418	COG5001	Diguanylate cyclase
vfu_A01418	COG5002	protein histidine kinase activity
vfu_A01420	COG2814	Major facilitator Superfamily
vfu_A01422	COG4773	Receptor
vfu_A01423	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
vfu_A01425	COG2382	esterase
vfu_A01428	COG1881	PFAM PEBP family protein
vfu_A01429	COG2207	Transcriptional regulator
vfu_A01433	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
vfu_A01434	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
vfu_A01441	COG0513	Belongs to the DEAD box helicase family
vfu_A01442	COG1368	sulfuric ester hydrolase activity
vfu_A01443	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
vfu_A01444	COG2194	sulfuric ester hydrolase activity
vfu_A01445	COG4566	intracellular signal transduction
vfu_A01453	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vfu_A01454	COG1271	oxidase subunit
vfu_A01455	COG1294	oxidase, subunit
vfu_A01464	COG2249	NAD(P)H dehydrogenase (quinone) activity
vfu_A01468	COG1021	2,3-dihydroxybenzoate-AMP ligase
vfu_A01469	COG1169	isochorismate synthase
vfu_A01470	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_A01471	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
vfu_A01473	COG2226	methyltransferase
vfu_A01473	COG3433	isochorismatase activity
vfu_A01473	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
vfu_A01477	COG4592	Periplasmic binding protein
vfu_A01478	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vfu_A01479	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vfu_A01480	COG4774	siderophore transport
vfu_A01480	COG1629	transport
vfu_A01482	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
vfu_A01483	COG1120	ATPase activity
vfu_A01485	COG1609	Transcriptional regulator
vfu_A01486	COG2723	6-phospho-beta-galactosidase activity
vfu_A01488	COG1741	Belongs to the pirin family
vfu_A01489	COG0352	thiamine-phosphate diphosphorylase activity
vfu_A01491	COG0351	phosphomethylpyrimidine kinase
vfu_A01492	COG4172	Belongs to the ABC transporter superfamily
vfu_A01494	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
vfu_A01495	COG0601	transmembrane transport
vfu_A01496	COG0747	negative chemotaxis
vfu_A01498	COG1538	Outer membrane efflux protein
vfu_A01499	COG1566	PFAM secretion protein HlyD family protein
vfu_A01500	COG2814	Major facilitator Superfamily
vfu_A01501	COG2207	Transcriptional regulator
vfu_A01501	COG3708	Transcriptional regulator
vfu_A01503	COG0745	RESPONSE REGULATOR receiver
vfu_A01505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
vfu_A01505	COG1263	PTS System
vfu_A01506	COG1609	Transcriptional regulator
vfu_A01507	COG1621	beta-fructofuranosidase activity
vfu_A01509	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
vfu_A01513	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_A01515	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
vfu_A01520	COG2986	histidine ammonia-lyase
vfu_A01521	COG1216	Glycosyl transferase, family 2
vfu_A01525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
vfu_A01526	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
vfu_A01527	COG0204	Acyl-transferase
vfu_A01527	COG0318	PFAM AMP-dependent synthetase and ligase
vfu_A01534	COG0601	transmembrane transport
vfu_A01535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
vfu_A01536	COG0444	Belongs to the ABC transporter superfamily
vfu_A01539	COG0435	Glutathione S-transferase
vfu_A01540	COG3174	membrane
vfu_A01541	COG0280	phosphate acetyltransferase
vfu_A01541	COG0857	belongs to the CobB CobQ family
vfu_A01542	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
vfu_A01543	COG3092	negative regulation of chromosome organization
vfu_A01545	COG4120	Belongs to the binding-protein-dependent transport system permease family
vfu_A01547	COG3706	GGDEF domain
vfu_A01549	COG2165	general secretion pathway protein
vfu_A01550	COG0653	protein targeting
vfu_A01551	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
vfu_A01552	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
vfu_A01553	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
vfu_A01556	COG0243	molybdopterin cofactor binding
vfu_A01557	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
vfu_A01557	COG1648	precorrin-2 dehydrogenase activity
vfu_A01561	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
vfu_A01561	COG1116	anion transmembrane transporter activity
vfu_A01562	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
vfu_A01563	COG1116	anion transmembrane transporter activity
vfu_A01564	COG2146	nitrite reductase [NAD(P)H] activity
vfu_A01564	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
vfu_A01566	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
vfu_A01567	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
vfu_A01568	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
vfu_A01569	COG0156	8-amino-7-oxononanoate synthase activity
vfu_A01570	COG2226	methyltransferase
vfu_A01571	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
vfu_A01573	COG0501	Belongs to the peptidase M48B family
vfu_A01576	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_A01579	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
vfu_A01583	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
vfu_A01584	COG2915	High frequency lysogenization protein hflD homolog
vfu_A01585	COG0482	sulfurtransferase activity
vfu_A01586	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
vfu_A01587	COG2916	Histone family protein nucleoid-structuring protein H-NS
vfu_A01588	COG1757	Na H antiporter
vfu_A01591	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
vfu_A01592	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
vfu_A01593	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
vfu_A01594	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
vfu_A01594	COG0131	Imidazoleglycerol-phosphate dehydratase
vfu_A01595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
vfu_A01596	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
vfu_A01598	COG0140	phosphoribosyl-ATP diphosphatase activity
vfu_A01598	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
vfu_A01599	COG1187	pseudouridine synthase activity
vfu_A01601	COG1695	Transcriptional regulator
vfu_A01602	COG2223	nitrite transmembrane transporter activity
vfu_A01604	COG1278	Cold shock
vfu_A01605	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
vfu_A01606	COG0542	response to heat
vfu_A01607	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
vfu_A01608	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
vfu_A01609	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
vfu_A01611	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
vfu_A01613	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
vfu_A01614	COG3706	GGDEF domain
vfu_A01614	COG0745	RESPONSE REGULATOR receiver
vfu_A01616	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
vfu_A01617	COG0297	glycogen (starch) synthase activity
vfu_A01621	COG3070	regulator of competence-specific genes
vfu_A01622	COG1609	Transcriptional regulator
vfu_A01623	COG3381	protein complex oligomerization
vfu_A01624	COG0745	RESPONSE REGULATOR receiver
vfu_A01625	COG1434	Gram-negative-bacterium-type cell wall biogenesis
vfu_A01626	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
vfu_A01627	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
vfu_A01628	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
vfu_A01629	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
vfu_A01633	COG4067	protein conserved in archaea
vfu_A01633	COG0189	ligase activity
vfu_A01634	COG0500	methyltransferase
vfu_A01635	COG4106	trans-aconitate 2-methyltransferase activity
vfu_A01636	COG1801	Protein of unknown function DUF72
vfu_A01638	COG1435	thymidine kinase activity
vfu_A01639	COG1434	Gram-negative-bacterium-type cell wall biogenesis
vfu_A01640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
vfu_A01641	COG0583	DNA-binding transcription factor activity
vfu_A01644	COG2116	formate transmembrane transporter activity
vfu_A01645	COG0390	transport system, permease component
vfu_A01646	COG4459	periplasmic nitrate reductase
vfu_A01647	COG3005	denitrification pathway
vfu_A01648	COG0243	molybdopterin cofactor binding
vfu_A01652	COG1227	inorganic diphosphatase activity
vfu_A01655	COG4172	Belongs to the ABC transporter superfamily
vfu_A01657	COG4171	peptide transport system, permease
vfu_A01658	COG4168	peptide transport system, permease
vfu_A01660	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
vfu_A01661	COG1842	Phage shock protein A
vfu_A01664	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
vfu_A01667	COG2818	Glycosylase
vfu_A01668	COG0626	cystathionine gamma-synthase activity
vfu_A01670	COG0733	neurotransmitter:sodium symporter activity
vfu_A01672	COG0564	pseudouridine synthase activity
vfu_A01674	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
vfu_A01675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
vfu_A01676	COG4136	ATPase activity
vfu_A01677	COG4135	transport system, permease component
vfu_A01678	COG4134	Bacterial extracellular solute-binding protein
vfu_A01680	COG3313	Fe-S protein
vfu_A01682	COG0842	Transport permease protein
vfu_A01683	COG1131	(ABC) transporter
vfu_A01685	COG0814	amino acid
vfu_A01687	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
vfu_A01690	COG1278	Cold shock
vfu_A01696	COG1737	Transcriptional regulator
vfu_A01700	COG3069	C4-dicarboxylate transmembrane transporter activity
vfu_A01701	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
vfu_A01703	COG3153	acetyltransferase
vfu_A01706	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
vfu_A01708	COG0642	Histidine kinase
vfu_A01709	COG0745	RESPONSE REGULATOR receiver
vfu_A01711	COG1061	Type III restriction enzyme res subunit
vfu_A01713	COG2814	Major facilitator Superfamily
vfu_A01715	COG0702	epimerase
vfu_A01716	COG0534	Mate efflux family protein
vfu_A01717	COG4181	ATPase activity
vfu_A01729	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
vfu_A01732	COG3265	gluconokinase activity
vfu_A01733	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
vfu_A01739	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
vfu_A01741	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
vfu_A01744	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
vfu_A01749	COG2989	Protein conserved in bacteria
vfu_A01750	COG3108	Peptidase M15
vfu_A01751	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
vfu_A01755	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
vfu_A01760	COG1846	Transcriptional regulator
vfu_A01761	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
vfu_A01762	COG0840	transmembrane signaling receptor activity
vfu_A01763	COG2176	DNA-directed DNA polymerase activity
vfu_A01766	COG1448	Aminotransferase
vfu_A01769	COG0017	Asparaginyl-tRNA synthetase
vfu_A01771	COG0720	synthase
vfu_A01775	COG0577	efflux transmembrane transporter activity
vfu_A01775	COG1136	(ABC) transporter
vfu_A01776	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
vfu_A01777	COG1760	l-serine dehydratase
vfu_A01778	COG0814	amino acid
vfu_A01779	COG0494	nUDIX hydrolase
vfu_A01781	COG0784	Response regulator, receiver
vfu_A01781	COG2205	protein histidine kinase activity
vfu_A01782	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
vfu_A01785	COG3106	COG3106 Predicted ATPase
vfu_A01787	COG3283	Transcriptional regulator of aromatic amino acids metabolism
vfu_A01788	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
vfu_A01793	COG0471	metal ion transport
vfu_A01794	COG4191	Histidine kinase
vfu_A01794	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vfu_A01797	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
vfu_A01798	COG0778	Nitroreductase
vfu_A01799	COG2991	Protein conserved in bacteria
vfu_A01802	COG3250	beta-galactosidase activity
vfu_A01804	COG1129	ABC transporter
vfu_A01812	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
vfu_A01812	COG2169	Transcriptional regulator
vfu_A01814	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
vfu_A01815	COG0372	Belongs to the citrate synthase family
vfu_A01816	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
vfu_A01820	COG1566	PFAM secretion protein HlyD family protein
vfu_A01821	COG2814	Major facilitator Superfamily
vfu_A01825	COG2195	Cleaves the N-terminal amino acid of tripeptides
vfu_A01826	COG2200	EAL domain
vfu_A01828	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
vfu_A01830	COG0625	glutathione transferase activity
vfu_A01834	COG2731	YhcH YjgK YiaL family protein
vfu_A01836	COG1349	DNA-binding transcription factor activity
vfu_A01837	COG3842	ATPase activity
vfu_A01838	COG3842	ATPase activity
vfu_A01839	COG3842	ATPase activity
vfu_A01840	COG3842	ATPase activity
vfu_A01841	COG0395	ABC-type sugar transport system, permease component
vfu_A01842	COG1175	transmembrane transport
vfu_A01848	COG0811	peptide transport
vfu_A01849	COG0811	peptide transport
vfu_A01850	COG0848	biopolymer transport protein
vfu_A01854	COG4667	esterase of the alpha-beta hydrolase superfamily
vfu_A01855	COG1793	dna ligase
vfu_A01858	COG0307	riboflavin synthase, alpha
vfu_A01862	COG0791	NLP P60 protein
vfu_A01866	COG1940	carbohydrate kinase activity
vfu_A01868	COG0303	'Molybdopterin
vfu_A01869	COG0746	molybdenum cofactor guanylyltransferase activity
vfu_A01870	COG3842	ATPase activity
vfu_A01871	COG4662	Binding-protein-dependent transport system inner membrane component
vfu_A01874	COG2204	response regulator
vfu_A01875	COG3852	Histidine kinase
vfu_A01878	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
vfu_A01882	COG3381	protein complex oligomerization
vfu_A01884	COG3383	formate dehydrogenase (NAD+) activity
vfu_A01884	COG0243	molybdopterin cofactor binding
vfu_A01885	COG0437	4 iron, 4 sulfur cluster binding
vfu_A01888	COG0004	ammonium transporteR
vfu_A01889	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
vfu_A01890	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
vfu_A01891	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
vfu_A01892	COG1177	transmembrane transport
vfu_A01893	COG1176	ABC-type spermidine putrescine transport system, permease component I
vfu_A01894	COG3842	ATPase activity
vfu_A01899	COG0589	response to stress
vfu_A01900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
vfu_A01903	COG2217	Heavy metal translocating P-type atpase
vfu_A01905	COG2010	Cytochrome c
vfu_A01908	COG3278	Belongs to the heme-copper respiratory oxidase family
vfu_A01920	COG3120	sequence-specific DNA binding
vfu_A01922	COG1067	ATP-dependent peptidase activity
vfu_A01923	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
vfu_A01925	COG0488	(ABC) transporter
vfu_A01927	COG0116	Belongs to the methyltransferase superfamily
vfu_A01927	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
vfu_A01930	COG0167	dihydroorotate dehydrogenase activity
vfu_A01931	COG2902	Dehydrogenase
vfu_A01932	COG0308	aminopeptidase N
vfu_A01933	COG0308	aminopeptidase N
vfu_A01937	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
vfu_A01938	COG1956	GAF domain-containing protein
vfu_A01939	COG1132	(ABC) transporter
vfu_A01940	COG2995	paraquat-inducible protein a
vfu_A01941	COG3008	intermembrane lipid transfer
vfu_A01942	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
vfu_A01942	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
vfu_A01943	COG2996	Protein conserved in bacteria
vfu_A01947	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
vfu_A01949	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
vfu_A01952	COG1115	amino acid carrier protein
vfu_A01957	COG3501	Rhs element vgr protein
vfu_A01959	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
vfu_A01963	COG1414	Transcriptional regulator
vfu_A01964	COG0583	DNA-binding transcription factor activity
vfu_A01966	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
vfu_A01969	COG0446	pyridine nucleotide-disulphide oxidoreductase
vfu_A01971	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
vfu_A01976	COG3384	dioxygenase
vfu_A01979	COG1643	Atp-dependent helicase
vfu_A01980	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
vfu_A01986	COG3706	GGDEF domain
vfu_A01989	COG0443	Heat shock 70 kDa protein
vfu_A01990	COG3706	GGDEF domain
vfu_A01996	COG2999	glutathione oxidoreductase activity
vfu_A02000	COG0243	molybdopterin cofactor binding
vfu_A02001	COG3005	denitrification pathway
vfu_A02002	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
vfu_A02003	COG0602	queuosine metabolic process
vfu_A02004	COG0561	phosphatase activity
vfu_A02006	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vfu_A02007	COG4597	amino acid ABC transporter
vfu_A02008	COG0765	amino acid transport
vfu_A02009	COG1126	abc transporter atp-binding protein
vfu_A02010	COG0670	Belongs to the BI1 family
vfu_A02011	COG2920	part of a sulfur-relay system
vfu_A02012	COG1254	Belongs to the acylphosphatase family
vfu_A02014	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
vfu_A02015	COG3391	amine dehydrogenase activity
vfu_A02017	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
vfu_A02021	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
vfu_A02023	COG5002	protein histidine kinase activity
vfu_A02024	COG0745	RESPONSE REGULATOR receiver
vfu_A02030	COG0668	transmembrane transport
vfu_A02037	COG3706	GGDEF domain
vfu_A02037	COG0745	RESPONSE REGULATOR receiver
vfu_A02040	COG2897	thiosulfate sulfurtransferase activity
vfu_A02041	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
vfu_A02042	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
vfu_A02044	COG0375	protein maturation
vfu_A02045	COG0309	Hydrogenase expression formation protein (HypE)
vfu_A02047	COG0298	carbon dioxide binding
vfu_A02048	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
vfu_A02050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
vfu_A02051	COG3604	Transcriptional regulator
vfu_A02052	COG3383	formate dehydrogenase (NAD+) activity
vfu_A02053	COG3383	formate dehydrogenase (NAD+) activity
vfu_A02054	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
vfu_A02055	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
vfu_A02057	COG3260	NADH ubiquinone oxidoreductase 20
vfu_A02058	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
vfu_A02059	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
vfu_A02059	COG3261	NADH dehydrogenase
vfu_A02060	COG0650	Formate hydrogenlyase subunit 4
vfu_A02061	COG0651	ATP synthesis coupled electron transport
vfu_A02062	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
vfu_A02064	COG1921	L-seryl-tRNASec selenium transferase activity
vfu_A02065	COG0835	chemotaxis
vfu_A02065	COG0784	Response regulator, receiver
vfu_A02067	COG4565	transcriptional regulatory protein
vfu_A02068	COG3290	protein histidine kinase activity
vfu_A02071	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
vfu_A02075	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
vfu_A02076	COG3063	Type IV pilus biogenesis stability protein PilW
vfu_A02079	COG1451	nucleotide metabolic process
vfu_A02081	COG0583	DNA-binding transcription factor activity
vfu_A02086	COG0110	maltose O-acetyltransferase activity
vfu_A02087	COG0840	transmembrane signaling receptor activity
vfu_A02089	COG1874	Beta-galactosidase
vfu_A02091	COG3833	ABC-type maltose transport systems, permease component
vfu_A02092	COG1175	transmembrane transport
vfu_A02093	COG2182	Extracellular solute-binding protein
vfu_A02095	COG1609	Transcriptional regulator
vfu_A02105	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
vfu_A02106	COG4139	cobalamin transport
vfu_A02107	COG2988	succinylglutamate desuccinylase activity
vfu_A02110	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
vfu_A02111	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
vfu_A02112	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
vfu_A02120	COG2925	Exonuclease
vfu_A02123	COG1346	cytolysis
vfu_A02124	COG0295	cytidine deaminase activity
vfu_A02125	COG5001	Diguanylate cyclase
vfu_A02130	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
vfu_A02132	COG0500	methyltransferase
vfu_A02134	COG0776	regulation of translation
vfu_A02136	COG0072	phenylalanine-tRNA ligase activity
vfu_A02136	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
vfu_A02137	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
vfu_A02139	COG3706	GGDEF domain
vfu_A02139	COG0745	RESPONSE REGULATOR receiver
vfu_A02140	COG2133	pyrroloquinoline quinone binding
vfu_A02142	COG0322	excinuclease ABC activity
vfu_A02143	COG2197	response regulator
vfu_A02145	COG0417	DNA replication proofreading
vfu_A02147	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
vfu_A02152	COG1228	amidohydrolase
vfu_A02153	COG0010	Belongs to the arginase family
vfu_A02155	COG2986	histidine ammonia-lyase
vfu_A02159	COG0277	FAD linked oxidase domain protein
vfu_A02159	COG0247	lactate metabolic process
vfu_A02163	COG2885	chlorophyll binding
vfu_A02168	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
vfu_A02170	COG2957	Belongs to the agmatine deiminase family
vfu_A02172	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
vfu_A02173	COG1012	belongs to the aldehyde dehydrogenase family
vfu_A02174	COG1917	Cupin 2, conserved barrel domain protein
vfu_A02174	COG1396	sequence-specific DNA binding
vfu_A02175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
vfu_A02176	COG0174	glutamine synthetase
vfu_A02177	COG1757	Na H antiporter
vfu_A02180	COG0583	DNA-binding transcription factor activity
vfu_A02183	COG1643	Atp-dependent helicase
vfu_A02184	COG0281	malic enzyme
vfu_A02186	COG0583	DNA-binding transcription factor activity
vfu_A02189	COG0640	Transcriptional regulator
vfu_A02193	COG2949	membrane
vfu_A02195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
vfu_A02200	COG0492	ferredoxin-NADP+ reductase activity
vfu_A02201	COG4988	ABC transporter
vfu_A02202	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
vfu_A02206	COG1187	pseudouridine synthase activity
vfu_A02207	COG0009	L-threonylcarbamoyladenylate synthase
vfu_A02209	COG0800	Aldolase
vfu_A02210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
vfu_A02211	COG4145	pantothenate transmembrane transporter activity
vfu_A02213	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
vfu_A02216	COG0613	PHP domain protein
vfu_A02218	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
vfu_A02219	COG0512	Glutamine amidotransferase of anthranilate synthase
vfu_A02220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
vfu_A02221	COG0134	indole-3-glycerol-phosphate synthase activity
vfu_A02221	COG0135	phosphoribosylanthranilate isomerase activity
vfu_A02222	COG0133	tryptophan synthase activity
vfu_A02224	COG1301	dicarboxylic acid transport
vfu_A02226	COG1607	acyl-coa hydrolase
vfu_A02227	COG2350	Protein conserved in bacteria
vfu_A02230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
vfu_A02232	COG1360	Flagellar Motor Protein
vfu_A02233	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
vfu_A02234	COG1191	sigma factor activity
vfu_A02239	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
vfu_A02240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
vfu_A02242	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
vfu_A02244	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
vfu_A02250	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
vfu_A02252	COG1677	Flagellar hook-basal body complex protein FliE
vfu_A02258	COG1706	bacterial-type flagellum-dependent cell motility
vfu_A02259	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
vfu_A02260	COG4786	Flagellar basal body rod
vfu_A02262	COG1749	Flagellar hook protein flgE
vfu_A02264	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
vfu_A02265	COG1558	bacterial-type flagellum-dependent cell motility
vfu_A02266	COG1815	bacterial-type flagellum-dependent cell motility
vfu_A02268	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
vfu_A02270	COG1987	bacterial-type flagellum assembly
vfu_A02275	COG0583	DNA-binding transcription factor activity
vfu_A02278	COG0612	Peptidase, M16
vfu_A02282	COG2771	luxR family
vfu_A02282	COG2200	EAL domain
vfu_A02283	COG0840	transmembrane signaling receptor activity
vfu_A02286	COG0583	DNA-binding transcription factor activity
vfu_A02288	COG0346	lactoylglutathione lyase activity
vfu_A02290	COG0488	(ABC) transporter
vfu_A02291	COG1032	radical SAM domain protein
vfu_A02292	COG2211	Major facilitator Superfamily
vfu_A02293	COG3940	Belongs to the glycosyl hydrolase 43 family
vfu_A02295	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
vfu_A02297	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vfu_A02297	COG4191	Histidine kinase
vfu_A02301	COG3070	regulator of competence-specific genes
vfu_A02304	COG2431	L-lysine efflux transmembrane transporter activity
vfu_A02306	COG0076	glutamate decarboxylase activity
vfu_A02307	COG1737	Transcriptional regulator
vfu_A02309	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
vfu_A02312	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
vfu_A02313	COG1960	acyl-CoA dehydrogenase activity
vfu_A02317	COG1012	belongs to the aldehyde dehydrogenase family
vfu_A02319	COG0700	Nucleoside recognition
vfu_A02320	COG3366	ferrous iron transmembrane transporter activity
vfu_A02324	COG0191	fructose-bisphosphate aldolase activity
vfu_A02326	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
vfu_A02327	COG3716	PTS system mannose fructose sorbose family IID component
vfu_A02328	COG3715	PTS system
vfu_A02330	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
vfu_A02331	COG2222	sugar isomerase
vfu_A02333	COG1349	DNA-binding transcription factor activity
vfu_A02335	COG1349	DNA-binding transcription factor activity
vfu_A02337	COG0784	Response regulator, receiver
vfu_A02337	COG5002	protein histidine kinase activity
vfu_A02340	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
vfu_A02341	COG2885	chlorophyll binding
vfu_A02342	COG0823	Involved in the tonB-independent uptake of proteins
vfu_A02345	COG0811	peptide transport
vfu_A02346	COG0824	Thioesterase
vfu_A02348	COG4890	Cyd operon protein YbgT
vfu_A02349	COG1294	oxidase, subunit
vfu_A02350	COG1271	oxidase subunit
vfu_A02351	COG2255	four-way junction helicase activity
vfu_A02352	COG0632	four-way junction helicase activity
vfu_A02353	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
vfu_A02354	COG0215	cysteine-tRNA ligase activity
vfu_A02355	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
vfu_A02356	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
vfu_A02357	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
vfu_A02358	COG3012	SEC-C Motif Domain Protein
vfu_A02359	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
vfu_A02361	COG1199	ATP-dependent helicase activity
vfu_A02362	COG3923	Primosomal replication protein n
vfu_A02365	COG0708	Exodeoxyribonuclease III
vfu_A02366	COG4160	amino acid transport
vfu_A02367	COG4215	(ABC) transporter
vfu_A02371	COG1882	Formate acetyltransferase
vfu_A02372	COG1882	Formate acetyltransferase
vfu_A02373	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
vfu_A02377	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
vfu_A02380	COG3713	MltA-interacting MipA family protein
vfu_A02382	COG2766	serine protein kinase
vfu_A02383	COG2718	Belongs to the UPF0229 family
vfu_A02384	COG2719	SpoVR family
vfu_A02385	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
vfu_A02387	COG1663	tetraacyldisaccharide 4'-kinase activity
vfu_A02388	COG1132	(ABC) transporter
vfu_A02389	COG0658	competence protein
vfu_A02389	COG2333	competence protein COMEC
vfu_A02391	COG4591	ABC-type transport system involved in lipoprotein release permease component
vfu_A02392	COG1136	(ABC) transporter
vfu_A02393	COG4591	ABC-type transport system involved in lipoprotein release permease component
vfu_A02395	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
vfu_A02398	COG1252	NADH dehydrogenase
vfu_A02405	COG0537	adenosine 5'-monophosphoramidase activity
vfu_A02408	COG2186	Transcriptional regulator
vfu_A02409	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
vfu_A02410	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
vfu_A02411	COG1674	ftsk spoiiie
vfu_A02412	COG1522	sequence-specific DNA binding
vfu_A02413	COG0686	Belongs to the AlaDH PNT family
vfu_A02415	COG0583	DNA-binding transcription factor activity
vfu_A02420	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
vfu_A02421	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
vfu_A02423	COG0539	negative regulation of cytoplasmic translation
vfu_A02424	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
vfu_A02425	COG1555	photosystem II stabilization
vfu_A02426	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
vfu_A02427	COG0776	regulation of translation
vfu_A02428	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
vfu_A02429	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
vfu_A02431	COG0544	peptidyl-prolyl cis-trans isomerase activity
vfu_A02432	COG4191	Histidine kinase
vfu_A02433	COG2204	response regulator
vfu_A02434	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
vfu_A02435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
vfu_A02436	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
vfu_A02437	COG1404	Belongs to the peptidase S8 family
vfu_A02439	COG2205	protein histidine kinase activity
vfu_A02440	COG0745	RESPONSE REGULATOR receiver
vfu_A02441	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
vfu_A02442	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
vfu_A02443	COG1760	l-serine dehydratase
vfu_A02445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
vfu_A02445	COG3153	acetyltransferase
vfu_A02449	COG4589	Belongs to the CDS family
vfu_A02456	COG2197	response regulator
vfu_A02457	COG3851	Histidine kinase
vfu_A02458	COG2271	Major facilitator Superfamily
vfu_A02459	COG1840	ABC-type Fe3 transport system, periplasmic component
vfu_A02461	COG3842	ATPase activity
vfu_A02462	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
vfu_A02464	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
vfu_A02466	COG2951	lytic endotransglycosylase activity
vfu_A02467	COG3100	YcgL domain-containing protein
vfu_A02468	COG0850	regulation of cytokinetic process
vfu_A02469	COG2894	cell division
vfu_A02470	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
vfu_A02473	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
vfu_A02474	COG0318	PFAM AMP-dependent synthetase and ligase
vfu_A02475	COG2267	carboxylic ester hydrolase activity
vfu_A02478	COG1214	PFAM Peptidase M22, glycoprotease
vfu_A02479	COG1199	ATP-dependent helicase activity
vfu_A02481	COG0788	formyltetrahydrofolate deformylase activity
vfu_A02482	COG0446	pyridine nucleotide-disulphide oxidoreductase
vfu_A02482	COG1902	pentaerythritol trinitrate reductase activity
vfu_A02483	COG0616	signal peptide processing
vfu_A02484	COG0252	asparaginase activity
vfu_A02485	COG3139	Protein of unknown function (DUF1315)
vfu_A02487	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
vfu_A02488	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
vfu_A02489	COG0676	glucose-6-phosphate 1-epimerase activity
vfu_A02490	COG2226	methyltransferase
vfu_A02493	COG0653	protein targeting
vfu_A02519	COG4695	Portal protein
vfu_A02539	COG4974	Belongs to the 'phage' integrase family
vfu_A02542	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
vfu_A02544	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
vfu_A02546	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
vfu_A02547	COG2832	Protein of unknown function (DUF454)
vfu_A02549	COG0745	RESPONSE REGULATOR receiver
vfu_A02550	COG0583	DNA-binding transcription factor activity
vfu_A02551	COG0778	Nitroreductase
vfu_A02552	COG1250	3-hydroxyacyl-CoA dehydrogenase
vfu_A02552	COG1024	Enoyl-CoA hydratase
vfu_A02553	COG0183	Belongs to the thiolase family
vfu_A02557	COG2067	long-chain fatty acid transport protein
vfu_A02558	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
vfu_A02563	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
vfu_A02564	COG2982	Protein involved in outer membrane biogenesis
vfu_A02565	COG0572	uridine kinase
vfu_A02567	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
vfu_A02567	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
vfu_A02568	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
vfu_A02568	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
vfu_A02570	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
vfu_A02572	COG0517	IMP dehydrogenase activity
vfu_A02572	COG0516	GMP reductase activity
vfu_A02573	COG3706	GGDEF domain
vfu_A02574	COG0314	molybdopterin synthase activity
vfu_A02575	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
vfu_A02576	COG0315	cyclic pyranopterin monophosphate synthase activity
vfu_A02577	COG0521	Mo-molybdopterin cofactor biosynthetic process
vfu_A02578	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
vfu_A02579	COG0391	Required for morphogenesis under gluconeogenic growth conditions
vfu_A02580	COG2198	Histidine kinase
vfu_A02581	COG2204	response regulator
vfu_A02582	COG0556	nucleotide-excision repair
vfu_A02584	COG1882	Formate acetyltransferase
vfu_A02585	COG4657	Part of a membrane complex involved in electron transport
vfu_A02586	COG2878	Part of a membrane complex involved in electron transport
vfu_A02587	COG4656	Part of a membrane complex involved in electron transport
vfu_A02588	COG4658	electron transport chain
vfu_A02589	COG4659	FMN binding
vfu_A02590	COG4660	Part of a membrane complex involved in electron transport
vfu_A02591	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
vfu_A02592	COG0346	lactoylglutathione lyase activity
vfu_A02595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
vfu_A02596	COG2056	Na+-H+ antiporter family
vfu_A02597	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
vfu_A02598	COG1286	toxin biosynthetic process
vfu_A02599	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
vfu_A02600	COG0285	dihydrofolate synthase activity
vfu_A02602	COG0101	tRNA pseudouridine synthase activity
vfu_A02604	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
vfu_A02605	COG2190	(PTS) system
vfu_A02605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
vfu_A02605	COG1263	PTS System
vfu_A02606	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
vfu_A02607	COG1846	Transcriptional regulator
vfu_A02607	COG1940	carbohydrate kinase activity
vfu_A02608	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
vfu_A02608	COG4651	solute:proton antiporter activity
vfu_A02609	COG0367	asparagine synthase
vfu_A02613	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
vfu_A02615	COG0326	Molecular chaperone. Has ATPase activity
vfu_A02616	COG3710	Transcriptional regulator
vfu_A02619	COG0622	Phosphoesterase
vfu_A02624	COG1090	epimerase
vfu_A02625	COG0300	oxidoreductase activity
vfu_A02626	COG3118	belongs to the thioredoxin family
vfu_A02627	COG0330	HflC and HflK could
vfu_A02629	COG0789	Transcriptional regulator
vfu_A02632	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
vfu_A02633	COG3115	cell septum assembly
vfu_A02634	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
vfu_A02635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
vfu_A02636	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
vfu_A02638	COG2190	(PTS) system
vfu_A02639	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
vfu_A02640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
vfu_A02641	COG1702	phosphate starvation-inducible protein PhoH
vfu_A02642	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
vfu_A02643	COG4535	Mg2 and Co2 transporter CorC
vfu_A02644	COG0815	Transfers the fatty acyl group on membrane lipoproteins
vfu_A02645	COG2888	peptidyl-tyrosine sulfation
vfu_A02646	COG0495	leucyl-tRNA aminoacylation
vfu_A02647	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
vfu_A02648	COG1466	dna polymerase III delta subunit
vfu_A02649	COG0799	negative regulation of ribosome biogenesis
vfu_A02650	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
vfu_A02651	COG0768	penicillin binding
vfu_A02652	COG0772	Belongs to the SEDS family
vfu_A02653	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
vfu_A02654	COG1686	Belongs to the peptidase S11 family
vfu_A02656	COG2921	Belongs to the UPF0250 family
vfu_A02657	COG0321	lipoyl(octanoyl) transferase activity
vfu_A02658	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
vfu_A02663	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
vfu_A02664	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
vfu_A02666	COG2197	response regulator
vfu_A02667	COG3851	Histidine kinase
vfu_A02668	COG2271	Major facilitator Superfamily
vfu_A02669	COG0366	Alpha amylase catalytic
vfu_A02670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
vfu_A02670	COG1263	PTS System
vfu_A02674	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
vfu_A02675	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
vfu_A02676	COG2011	ABC-type metal ion transport system permease component
vfu_A02677	COG1464	Belongs to the NlpA lipoprotein family
vfu_A02678	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
vfu_A02680	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
vfu_A02680	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
vfu_A02682	COG3706	GGDEF domain
vfu_A02682	COG0745	RESPONSE REGULATOR receiver
vfu_A02683	COG1611	Belongs to the LOG family
vfu_A02684	COG1611	Belongs to the LOG family
vfu_A02685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
vfu_A02687	COG2363	Small membrane protein
vfu_A02689	COG0583	DNA-binding transcription factor activity
vfu_A02691	COG0301	tRNA thio-modification
vfu_A02691	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
vfu_A02693	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
vfu_A02695	COG0142	geranyltranstransferase activity
vfu_A02696	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
vfu_A02697	COG0564	pseudouridine synthase activity
vfu_A02698	COG3098	single-species biofilm formation
vfu_A02702	COG1671	Belongs to the UPF0178 family
vfu_A02704	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
vfu_A02705	COG0254	rRNA binding
vfu_A02706	COG1720	tRNA m6t6A37 methyltransferase activity
vfu_A02707	COG0442	prolyl-tRNA aminoacylation
vfu_A02712	COG0047	phosphoribosylformylglycinamidine synthase activity
vfu_A02712	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
vfu_A02713	COG0047	phosphoribosylformylglycinamidine synthase activity
vfu_A02713	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
vfu_A02714	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
vfu_A02717	COG0590	tRNA wobble adenosine to inosine editing
vfu_A02718	COG0583	DNA-binding transcription factor activity
vfu_A02720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
vfu_A02721	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
vfu_A02727	COG0484	heat shock protein binding
vfu_A02728	COG0443	Heat shock 70 kDa protein
vfu_A02730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
vfu_A02731	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
vfu_A02732	COG0497	DNA recombination
vfu_A02733	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
vfu_A02734	COG2914	Belongs to the UPF0125 (RnfH) family
vfu_A02735	COG2867	negative regulation of translational initiation
vfu_A02736	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
vfu_A02741	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
vfu_A02742	COG0583	DNA-binding transcription factor activity
vfu_A02743	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
vfu_A02745	COG1115	amino acid carrier protein
vfu_A02750	COG3121	Chaperone
vfu_A02751	COG3188	usher protein
vfu_A02753	COG3710	Transcriptional regulator
vfu_A02754	COG1584	GPR1 FUN34 yaaH family protein
vfu_A02761	COG4691	Plasmid stability protein
vfu_A02765	COG0582	viral genome integration into host DNA
vfu_A02766	COG0518	GMP synthase (glutamine-hydrolyzing) activity
vfu_A02766	COG0519	Catalyzes the synthesis of GMP from XMP
vfu_A02767	COG0517	IMP dehydrogenase activity
vfu_A02767	COG0516	GMP reductase activity
vfu_A02771	COG1160	GTP binding
vfu_A02772	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
vfu_A02773	COG2976	Protein conserved in bacteria
vfu_A02774	COG0124	histidyl-tRNA synthetase
vfu_A02775	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
vfu_A02776	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
vfu_A02780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
vfu_A02781	COG2975	iron-sulfur cluster assembly
vfu_A02782	COG0633	Ferredoxin
vfu_A02783	COG0443	Heat shock 70 kDa protein
vfu_A02786	COG0822	iron-sulfur transferase activity
vfu_A02787	COG1104	cysteine desulfurase activity
vfu_A02788	COG1959	2 iron, 2 sulfur cluster binding
vfu_A02789	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
vfu_A02790	COG0483	inositol monophosphate 1-phosphatase activity
vfu_A02791	COG1335	isochorismatase
vfu_A02792	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
vfu_A02793	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
vfu_A02794	COG1862	Preprotein translocase
vfu_A02795	COG0343	queuine tRNA-ribosyltransferase activity
vfu_A02796	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
vfu_A02797	COG0517	IMP dehydrogenase activity
vfu_A02800	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
vfu_A02801	COG0583	DNA-binding transcription factor activity
vfu_A02802	COG0450	alkyl hydroperoxide reductase
vfu_A02803	COG3142	Participates in the control of copper homeostasis
vfu_A02805	COG0704	Plays a role in the regulation of phosphate uptake
vfu_A02806	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
vfu_A02807	COG0581	inorganic phosphate transmembrane transporter activity
vfu_A02808	COG0573	inorganic phosphate transmembrane transporter activity
vfu_A02809	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
vfu_A02810	COG0248	Ppx GppA phosphatase
vfu_A02812	COG5002	protein histidine kinase activity
vfu_A02813	COG0745	RESPONSE REGULATOR receiver
vfu_A02814	COG2974	May be involved in recombination
vfu_A02816	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
vfu_A02818	COG0477	Major facilitator Superfamily
vfu_A02820	COG1595	DNA-templated transcription, initiation
vfu_A02822	COG3248	Nucleoside-binding outer membrane protein
vfu_A02823	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
vfu_A02824	COG0693	protein deglycase activity
vfu_A02825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
vfu_A02826	COG2166	iron-sulfur cluster assembly
vfu_A02827	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
vfu_A02828	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
vfu_A02831	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
vfu_A02831	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
vfu_A02833	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
vfu_A02834	COG1074	ATP-dependent DNA helicase activity
vfu_A02835	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
vfu_A02837	COG0583	DNA-binding transcription factor activity
vfu_A02838	COG3141	response to X-ray
vfu_A02839	COG2171	N-acyltransferase activity
vfu_A02840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
vfu_A02847	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
vfu_A02848	COG2017	converts alpha-aldose to the beta-anomer
vfu_A02850	COG2059	Chromate
vfu_A02861	COG4964	Belongs to the GSP D family
vfu_A02869	COG0583	DNA-binding transcription factor activity
vfu_A02871	COG0583	DNA-binding transcription factor activity
vfu_A02872	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
vfu_A02873	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
vfu_A02875	COG0560	Phosphoserine phosphatase
vfu_A02877	COG0813	purine-nucleoside phosphorylase activity
vfu_A02879	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
vfu_A02880	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
vfu_A02881	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
vfu_A02883	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
vfu_A02884	COG0084	hydrolase, TatD family'
vfu_A02887	COG1115	amino acid carrier protein
vfu_A02888	COG1115	amino acid carrier protein
vfu_A02891	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
vfu_A02895	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
vfu_A02896	COG0083	homoserine kinase activity
vfu_A02899	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
vfu_A02901	COG0745	RESPONSE REGULATOR receiver
vfu_A02903	COG0784	Response regulator, receiver
vfu_A02903	COG5002	protein histidine kinase activity
vfu_A02903	COG2198	Histidine kinase
vfu_A02904	COG2203	Gaf domain
vfu_A02904	COG5001	Diguanylate cyclase
vfu_A02904	COG4251	negative regulation of phosphorylation
vfu_A02904	COG3706	GGDEF domain
vfu_A02905	COG1242	4 iron, 4 sulfur cluster binding
vfu_A02906	COG0069	glutamate synthase activity
vfu_A02906	COG0070	glutamate synthase
vfu_A02906	COG0067	glutamate synthase
vfu_A02908	COG0070	glutamate synthase
vfu_A02908	COG0069	glutamate synthase activity
vfu_A02908	COG0067	glutamate synthase
vfu_A02909	COG0493	'glutamate synthase
vfu_A02911	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
vfu_A02913	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
vfu_A02914	COG2860	membrane
vfu_A02918	COG0730	response to heat
vfu_A02919	COG3479	Phenolic acid decarboxylase
vfu_A02921	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
vfu_A02922	COG0505	Belongs to the CarA family
vfu_A02924	COG0494	nUDIX hydrolase
vfu_A02925	COG0653	protein targeting
vfu_A02927	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
vfu_A02928	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
vfu_A02929	COG0849	cell division
vfu_A02930	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
vfu_A02931	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
vfu_A02932	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
vfu_A02933	COG0772	Belongs to the SEDS family
vfu_A02934	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
vfu_A02935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
vfu_A02936	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
vfu_A02937	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
vfu_A02938	COG0768	penicillin binding
vfu_A02939	COG3116	cell division
vfu_A02940	COG0275	rRNA processing
vfu_A02941	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
vfu_A02942	COG3107	peptidoglycan biosynthetic process
vfu_A02943	COG0792	nuclease activity
vfu_A02944	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
vfu_A02945	COG2823	Periplasmic or secreted lipoprotein
vfu_A02946	COG2969	positive regulation of protein catabolic process
vfu_A02947	COG0625	glutathione transferase activity
vfu_A02948	COG2857	Cytochrome c1
vfu_A02949	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
vfu_A02950	COG0723	plastoquinol--plastocyanin reductase activity
vfu_A02951	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
vfu_A02952	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
vfu_A02953	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
vfu_A02954	COG3105	Protein conserved in bacteria
vfu_A02955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
vfu_A02956	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
vfu_A02957	COG0335	large ribosomal subunit rRNA binding
vfu_A02959	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
vfu_A02961	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
vfu_A02963	COG4137	Cytochrome C assembly protein
vfu_A02964	COG4536	flavin adenine dinucleotide binding
vfu_A02965	COG1854	S-ribosylhomocysteine lyase activity
vfu_A02967	COG2918	glutathione biosynthetic process
vfu_A02968	COG0612	Peptidase, M16
vfu_A02969	COG1238	metal cluster binding
vfu_A02970	COG1063	alcohol dehydrogenase
vfu_A02971	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
vfu_A02972	COG5016	pyruvate
vfu_A02972	COG0511	ligase activity, forming carbon-carbon bonds
vfu_A02973	COG3630	sodium ion export across plasma membrane
vfu_A02976	COG0527	aspartate kinase activity
vfu_A02977	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
vfu_A02978	COG2137	regulation of response to DNA damage stimulus
vfu_A02979	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
vfu_A02980	COG1546	Belongs to the CinA family
vfu_A02981	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
vfu_A02982	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
vfu_A02983	COG1388	LysM domain
vfu_A02983	COG4942	peptidase
vfu_A02984	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
vfu_A02985	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
vfu_A02986	COG0585	pseudouridine synthase activity
vfu_A02988	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
vfu_A02989	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
vfu_A02990	COG1968	undecaprenyl-diphosphatase activity
vfu_A02991	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
vfu_A02992	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
vfu_A02993	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
vfu_A02995	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
vfu_A02996	COG0828	Belongs to the bacterial ribosomal protein bS21 family
vfu_A02997	COG1610	YqeY-like protein
vfu_A02998	COG0358	DNA primase activity
vfu_A02999	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
vfu_A03013	COG2378	regulation of single-species biofilm formation
vfu_A03015	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
vfu_A03016	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
vfu_A03016	COG1263	PTS System
vfu_A03017	COG1609	Transcriptional regulator
vfu_A03019	COG2239	Acts as a magnesium transporter
vfu_A03023	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
vfu_A03024	COG1349	DNA-binding transcription factor activity
vfu_A03026	COG0469	pyruvate kinase activity
vfu_A03028	COG3706	GGDEF domain
vfu_A03032	COG1279	arginine transmembrane transporter activity
vfu_A03034	COG0668	transmembrane transport
vfu_A03035	COG0191	fructose-bisphosphate aldolase activity
vfu_A03036	COG0126	phosphoglycerate kinase activity
vfu_A03037	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
vfu_A03038	COG4771	TonB-dependent receptor
vfu_A03039	COG0583	DNA-binding transcription factor activity
vfu_A03040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
vfu_A03044	COG2356	endonuclease I
vfu_A03045	COG1385	rRNA (uridine-N3-)-methyltransferase activity
vfu_A03046	COG0189	ligase activity
vfu_A03047	COG1678	Uncharacterized ACR, COG1678
vfu_A03051	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
vfu_A03052	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
vfu_A03053	COG0762	integral membrane protein
vfu_A03054	COG1872	DUF167
vfu_A03057	COG0635	Involved in the biosynthesis of porphyrin-containing compound
vfu_A03059	COG0220	tRNA (guanine-N7-)-methyltransferase activity
vfu_A03060	COG1194	a g-specific adenine glycosylase
vfu_A03065	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
vfu_A03066	COG0741	lytic transglycosylase activity
vfu_A03068	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
vfu_A03069	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
vfu_A03070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
vfu_A03073	COG2967	ApaG domain
vfu_A03074	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
vfu_A03076	COG3610	response to peptide
vfu_A03077	COG2966	Psort location CytoplasmicMembrane, score
vfu_A03078	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
vfu_A03079	COG0211	Belongs to the bacterial ribosomal protein bL27 family
vfu_A03080	COG0261	This protein binds to 23S rRNA in the presence of protein L20
vfu_A03081	COG0142	geranyltranstransferase activity
vfu_A03082	COG0531	amino acid
vfu_A03084	COG0039	L-malate dehydrogenase activity
vfu_A03089	COG0589	response to stress
vfu_A03094	COG0312	modulator of DNA gyrase
vfu_A03095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
vfu_A03096	COG3164	Protein of unknown function
vfu_A03097	COG1530	ribonuclease E activity
vfu_A03098	COG0424	maF-like protein
vfu_A03099	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
vfu_A03100	COG1792	Involved in formation and maintenance of cell shape
vfu_A03101	COG1077	Cell shape determining protein MreB Mrl
vfu_A03111	COG1459	type II secretion system
vfu_A03112	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
vfu_A03114	COG3409	Peptidoglycan-binding domain 1 protein
vfu_A03114	COG3267	Type II secretory pathway component ExeA
vfu_A03119	COG2200	EAL domain
vfu_A03119	COG2199	diguanylate cyclase activity
vfu_A03120	COG0629	single-stranded DNA binding
vfu_A03123	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
vfu_A03125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
vfu_A03126	COG0527	aspartate kinase activity
vfu_A03127	COG1410	methionine synthase
vfu_A03127	COG0646	methionine synthase
vfu_A03133	COG0175	sulfate reduction
vfu_A03135	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
vfu_A03139	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
vfu_A03140	COG0735	belongs to the Fur family
vfu_A03142	COG0166	Belongs to the GPI family
vfu_A03143	COG0166	Belongs to the GPI family
vfu_A03145	COG0432	Pfam Uncharacterised protein family UPF0047
vfu_A03146	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
vfu_A03147	COG0305	Participates in initiation and elongation during chromosome replication
vfu_A03149	COG0359	binds to the 23S rRNA
vfu_A03151	COG2965	DNA replication, synthesis of RNA primer
vfu_A03152	COG0360	Binds together with S18 to 16S ribosomal RNA
vfu_A03154	COG2906	2 iron, 2 sulfur cluster binding
vfu_B00009	COG2026	Addiction module toxin, RelE StbE family
vfu_B00011	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_B00012	COG0010	Belongs to the arginase family
vfu_B00014	COG1252	NADH dehydrogenase
vfu_B00016	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
vfu_B00017	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
vfu_B00018	COG4232	protein-disulfide reductase activity
vfu_B00020	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
vfu_B00021	COG0110	maltose O-acetyltransferase activity
vfu_B00025	COG3008	intermembrane lipid transfer
vfu_B00025	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
vfu_B00026	COG2995	paraquat-inducible protein a
vfu_B00027	COG0318	PFAM AMP-dependent synthetase and ligase
vfu_B00029	COG1012	belongs to the aldehyde dehydrogenase family
vfu_B00030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
vfu_B00031	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
vfu_B00033	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
vfu_B00035	COG0583	DNA-binding transcription factor activity
vfu_B00037	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
vfu_B00039	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
vfu_B00040	COG0513	Belongs to the DEAD box helicase family
vfu_B00041	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
vfu_B00046	COG4633	Protein conserved in bacteria
vfu_B00047	COG4628	conserved protein (DUF2132)
vfu_B00055	COG0789	Transcriptional regulator
vfu_B00056	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
vfu_B00067	COG0454	-acetyltransferase
vfu_B00069	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_B00076	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
vfu_B00078	COG0494	nUDIX hydrolase
vfu_B00079	COG1280	lysine exporter protein (LysE YggA)
vfu_B00081	COG0456	acetyltransferase
vfu_B00083	COG1335	isochorismatase
vfu_B00089	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
vfu_B00090	COG1309	transcriptional regulator
vfu_B00093	COG0583	DNA-binding transcription factor activity
vfu_B00095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
vfu_B00098	COG2897	thiosulfate sulfurtransferase activity
vfu_B00099	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
vfu_B00101	COG0302	gtp cyclohydrolase
vfu_B00102	COG0531	amino acid
vfu_B00104	COG4303	Ethanolamine ammonia lyase large subunit
vfu_B00106	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
vfu_B00106	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
vfu_B00107	COG2759	Belongs to the formate--tetrahydrofolate ligase family
vfu_B00108	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
vfu_B00111	COG1011	Hydrolase
vfu_B00112	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
vfu_B00114	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
vfu_B00116	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
vfu_B00118	COG3842	ATPase activity
vfu_B00122	COG2866	Carboxypeptidase
vfu_B00127	COG4166	transmembrane transport
vfu_B00128	COG4174	ABC transporter (Permease)
vfu_B00129	COG4239	(ABC) transporter, permease
vfu_B00130	COG4172	Belongs to the ABC transporter superfamily
vfu_B00131	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
vfu_B00134	COG0784	Response regulator, receiver
vfu_B00134	COG2205	protein histidine kinase activity
vfu_B00135	COG5001	Diguanylate cyclase
vfu_B00135	COG4251	negative regulation of phosphorylation
vfu_B00135	COG3706	GGDEF domain
vfu_B00135	COG2203	Gaf domain
vfu_B00138	COG2199	diguanylate cyclase activity
vfu_B00141	COG2501	S4 domain
vfu_B00149	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
vfu_B00153	COG3710	Transcriptional regulator
vfu_B00157	COG4106	trans-aconitate 2-methyltransferase activity
vfu_B00162	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vfu_B00163	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
vfu_B00163	COG2207	Transcriptional regulator
vfu_B00165	COG2233	PERMEase
vfu_B00172	COG0765	amino acid transport
vfu_B00173	COG0765	amino acid transport
vfu_B00179	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
vfu_B00184	COG0402	S-adenosylhomocysteine deaminase activity
vfu_B00185	COG2351	hydroxyisourate hydrolase activity
vfu_B00193	COG1129	ABC transporter
vfu_B00194	COG1309	transcriptional regulator
vfu_B00196	COG3706	GGDEF domain
vfu_B00198	COG2199	diguanylate cyclase activity
vfu_B00201	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
vfu_B00202	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
vfu_B00203	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
vfu_B00224	COG0023	Translation Initiation Factor
vfu_B00227	COG1181	Belongs to the D-alanine--D-alanine ligase family
vfu_B00229	COG0045	succinate-CoA ligase (ADP-forming) activity
vfu_B00229	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
vfu_B00229	COG1042	CoA-binding domain protein
vfu_B00230	COG0583	DNA-binding transcription factor activity
vfu_B00231	COG1629	transport
vfu_B00231	COG4771	TonB-dependent receptor
vfu_B00235	COG2050	protein possibly involved in aromatic compounds catabolism
vfu_B00236	COG4783	chaperone-mediated protein folding
vfu_B00237	COG2824	Alkylphosphonate utilization operon protein PhnA
vfu_B00241	COG0737	Belongs to the 5'-nucleotidase family
vfu_B00242	COG3593	DNA synthesis involved in DNA repair
vfu_B00244	COG0583	DNA-binding transcription factor activity
vfu_B00245	COG2116	formate transmembrane transporter activity
vfu_B00247	COG3038	cytochrome b561
vfu_B00253	COG5001	Diguanylate cyclase
vfu_B00256	COG0243	molybdopterin cofactor binding
vfu_B00257	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
vfu_B00258	COG0784	Response regulator, receiver
vfu_B00258	COG5002	protein histidine kinase activity
vfu_B00258	COG2205	protein histidine kinase activity
vfu_B00259	COG3437	response regulator, receiver
vfu_B00261	COG2207	Transcriptional regulator
vfu_B00262	COG1064	alcohol dehydrogenase
vfu_B00263	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_B00264	COG1846	Transcriptional regulator
vfu_B00265	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
vfu_B00266	COG0523	cobalamin synthesis protein
vfu_B00267	COG0038	chloride channel
vfu_B00269	COG0156	8-amino-7-oxononanoate synthase activity
vfu_B00270	COG0784	Response regulator, receiver
vfu_B00270	COG2205	protein histidine kinase activity
vfu_B00271	COG0419	ATPase involved in DNA repair
vfu_B00272	COG0420	3'-5' exonuclease activity
vfu_B00273	COG1609	Transcriptional regulator
vfu_B00275	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
vfu_B00275	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
vfu_B00276	COG1105	Belongs to the carbohydrate kinase PfkB family
vfu_B00277	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
vfu_B00277	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
vfu_B00277	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
vfu_B00278	COG0189	ligase activity
vfu_B00278	COG4067	protein conserved in archaea
vfu_B00280	COG0602	queuosine metabolic process
vfu_B00281	COG1328	CTP reductase activity
vfu_B00290	COG0454	-acetyltransferase
vfu_B00292	COG0583	DNA-binding transcription factor activity
vfu_B00293	COG1280	lysine exporter protein (LysE YggA)
vfu_B00294	COG0745	RESPONSE REGULATOR receiver
vfu_B00296	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
vfu_B00297	COG0840	transmembrane signaling receptor activity
vfu_B00301	COG0545	Peptidyl-prolyl cis-trans isomerase
vfu_B00302	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
vfu_B00303	COG0840	transmembrane signaling receptor activity
vfu_B00304	COG2814	Major facilitator Superfamily
vfu_B00307	COG3069	C4-dicarboxylate transmembrane transporter activity
vfu_B00308	COG2197	response regulator
vfu_B00309	COG3850	Histidine kinase
vfu_B00312	COG0243	molybdopterin cofactor binding
vfu_B00314	COG3005	denitrification pathway
vfu_B00316	COG4166	transmembrane transport
vfu_B00320	COG0183	Belongs to the thiolase family
vfu_B00323	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
vfu_B00324	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
vfu_B00328	COG3706	GGDEF domain
vfu_B00329	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
vfu_B00331	COG2207	Transcriptional regulator
vfu_B00332	COG1979	alcohol dehydrogenase
vfu_B00334	COG0784	Response regulator, receiver
vfu_B00334	COG2205	protein histidine kinase activity
vfu_B00334	COG2198	Histidine kinase
vfu_B00335	COG1879	ABC-type sugar transport system periplasmic component
vfu_B00336	COG1803	Methylglyoxal synthase
vfu_B00337	COG1335	isochorismatase
vfu_B00338	COG0210	DNA helicase
vfu_B00347	COG1289	transmembrane transporter activity
vfu_B00351	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
vfu_B00352	COG4149	molybdate abc transporter
vfu_B00353	COG0725	ABC transporter, periplasmic molybdate-binding protein
vfu_B00354	COG1492	cobalamin metabolic process
vfu_B00358	COG0784	Response regulator, receiver
vfu_B00358	COG5002	protein histidine kinase activity
vfu_B00359	COG1879	ABC-type sugar transport system periplasmic component
vfu_B00360	COG2827	Endonuclease containing a URI domain
vfu_B00364	COG4974	Belongs to the 'phage' integrase family
vfu_B00392	COG2184	nucleotidyltransferase activity
vfu_B00393	COG4695	Portal protein
vfu_B00401	COG4386	tail sheath protein
vfu_B00410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
vfu_B00411	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
vfu_B00413	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
vfu_B00414	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
vfu_B00415	COG0247	lactate metabolic process
vfu_B00416	COG0247	lactate metabolic process
vfu_B00419	COG0297	glycogen (starch) synthase activity
vfu_B00419	COG0438	transferase activity, transferring glycosyl groups
vfu_B00420	COG0438	transferase activity, transferring glycosyl groups
vfu_B00429	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
vfu_B00433	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
vfu_B00434	COG3118	belongs to the thioredoxin family
vfu_B00435	COG2814	Major facilitator Superfamily
vfu_B00440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
vfu_B00440	COG1648	precorrin-2 dehydrogenase activity
vfu_B00442	COG2146	nitrite reductase [NAD(P)H] activity
vfu_B00443	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
vfu_B00447	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
vfu_B00448	COG4160	amino acid transport
vfu_B00449	COG4160	amino acid transport
vfu_B00450	COG4215	(ABC) transporter
vfu_B00451	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vfu_B00452	COG1126	abc transporter atp-binding protein
vfu_B00457	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
vfu_B00458	COG1120	ATPase activity
vfu_B00460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
vfu_B00462	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
vfu_B00465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
vfu_B00467	COG1070	Carbohydrate kinase
vfu_B00469	COG2390	Transcriptional regulator
vfu_B00472	COG1294	oxidase, subunit
vfu_B00473	COG1271	oxidase subunit
vfu_B00474	COG0243	molybdopterin cofactor binding
vfu_B00476	COG3781	membrane
vfu_B00477	COG0583	DNA-binding transcription factor activity
vfu_B00478	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
vfu_B00481	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
vfu_B00483	COG0330	HflC and HflK could
vfu_B00487	COG1917	Cupin 2, conserved barrel domain protein
vfu_B00487	COG2207	Transcriptional regulator
vfu_B00489	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
vfu_B00492	COG1609	Transcriptional regulator
vfu_B00492	COG2207	Transcriptional regulator
vfu_B00493	COG4604	ABC transporter, ATP-binding protein
vfu_B00494	COG4605	iron ion homeostasis
vfu_B00495	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vfu_B00497	COG0121	glutamine amidotransferase
vfu_B00499	COG4412	M6 family metalloprotease domain protein
vfu_B00499	COG3291	Pkd domain containing protein
vfu_B00500	COG5380	lipid catabolic process
vfu_B00501	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
vfu_B00502	COG0840	transmembrane signaling receptor activity
vfu_B00503	COG1522	sequence-specific DNA binding
vfu_B00507	COG2814	Major facilitator Superfamily
vfu_B00509	COG0840	transmembrane signaling receptor activity
vfu_B00512	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
vfu_B00513	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
vfu_B00514	COG3279	Response regulator of the LytR AlgR family
vfu_B00515	COG3275	phosphorelay sensor kinase activity
vfu_B00517	COG4989	oxidoreductase activity
vfu_B00519	COG0366	Alpha amylase catalytic
vfu_B00520	COG3227	Zinc metalloprotease (Elastase)
vfu_B00522	COG3047	cAMP biosynthetic process
vfu_B00524	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
vfu_B00526	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
vfu_B00529	COG1482	cell wall glycoprotein biosynthetic process
vfu_B00530	COG0840	transmembrane signaling receptor activity
vfu_B00531	COG4580	involved in the transport of maltose and maltodextrins
vfu_B00532	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
vfu_B00533	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
vfu_B00535	COG1609	Transcriptional regulator
vfu_B00537	COG2942	2-epimerase
vfu_B00539	COG0395	ABC-type sugar transport system, permease component
vfu_B00540	COG1175	transmembrane transport
vfu_B00544	COG0351	phosphomethylpyrimidine kinase
vfu_B00545	COG1116	anion transmembrane transporter activity
vfu_B00546	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
vfu_B00547	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
vfu_B00548	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
vfu_B00551	COG1132	(ABC) transporter
vfu_B00552	COG1132	(ABC) transporter
vfu_B00554	COG4943	cyclic-guanylate-specific phosphodiesterase activity
vfu_B00555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
vfu_B00561	COG1278	Cold shock
vfu_B00562	COG1063	alcohol dehydrogenase
vfu_B00563	COG0156	8-amino-7-oxononanoate synthase activity
vfu_B00564	COG1012	belongs to the aldehyde dehydrogenase family
vfu_B00565	COG3284	Transcriptional regulator
vfu_B00568	COG0346	lactoylglutathione lyase activity
vfu_B00571	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
vfu_B00574	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
vfu_B00575	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
vfu_B00576	COG0363	glucosamine-6-phosphate deaminase activity
vfu_B00577	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
vfu_B00584	COG1410	methionine synthase
vfu_B00584	COG0646	methionine synthase
vfu_B00585	COG0531	amino acid
vfu_B00588	COG1929	Belongs to the glycerate kinase type-1 family
vfu_B00589	COG2610	gluconate transmembrane transporter activity
vfu_B00590	COG3835	regulator
vfu_B00592	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
vfu_B00593	COG4533	DNA binding
vfu_B00605	COG3188	usher protein
vfu_B00606	COG3121	Chaperone
vfu_B00608	COG2885	chlorophyll binding
vfu_B00608	COG3047	cAMP biosynthetic process
vfu_B00610	COG1566	PFAM secretion protein HlyD family protein
vfu_B00614	COG1686	Belongs to the peptidase S11 family
vfu_B00616	COG0765	amino acid transport
vfu_B00619	COG1522	sequence-specific DNA binding
vfu_B00620	COG0010	Belongs to the arginase family
vfu_B00621	COG1166	arginine decarboxylase activity
vfu_B00623	COG4175	Glycine betaine
vfu_B00624	COG4176	ABC-type proline glycine betaine transport system permease component
vfu_B00625	COG2113	Glycine betaine
vfu_B00629	COG2239	Acts as a magnesium transporter
vfu_B00630	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
vfu_B00633	COG0113	porphobilinogen synthase activity
vfu_B00635	COG0784	Response regulator, receiver
vfu_B00635	COG3437	response regulator, receiver
vfu_B00640	COG0527	aspartate kinase activity
vfu_B00641	COG0662	Cupin 2, conserved barrel domain protein
vfu_B00642	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
vfu_B00643	COG0456	acetyltransferase
vfu_B00645	COG0861	Integral membrane protein TerC family
vfu_B00648	COG0534	Mate efflux family protein
vfu_B00649	COG2154	pterin-4-alpha-carbinolamine dehydratase
vfu_B00650	COG3186	Phenylalanine-4-hydroxylase
vfu_B00651	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
vfu_B00653	COG0642	Histidine kinase
vfu_B00654	COG0745	RESPONSE REGULATOR receiver
vfu_B00658	COG1022	Amp-dependent synthetase and ligase
vfu_B00666	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
vfu_B00667	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
vfu_B00667	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
vfu_B00669	COG2197	response regulator
vfu_B00670	COG2205	protein histidine kinase activity
vfu_B00670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vfu_B00671	COG3300	MHYT domain
vfu_B00671	COG5001	Diguanylate cyclase
vfu_B00678	COG3036	rescue of stalled ribosome
vfu_B00679	COG1278	Cold shock
vfu_B00680	COG4681	YaeQ
vfu_B00681	COG3706	GGDEF domain
vfu_B00682	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
vfu_B00682	COG1017	nitric oxide dioxygenase activity
vfu_B00683	COG3604	Transcriptional regulator
vfu_B00686	COG2195	Cleaves the N-terminal amino acid of tripeptides
vfu_B00687	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
vfu_B00689	COG0366	Alpha amylase catalytic
vfu_B00692	COG0840	transmembrane signaling receptor activity
vfu_B00693	COG0714	Associated with various cellular activities
vfu_B00697	COG2304	oxidoreductase activity
vfu_B00700	COG5001	Diguanylate cyclase
vfu_B00704	COG2205	protein histidine kinase activity
vfu_B00704	COG0784	Response regulator, receiver
vfu_B00704	COG5002	protein histidine kinase activity
vfu_B00705	COG3706	GGDEF domain
vfu_B00705	COG0745	RESPONSE REGULATOR receiver
vfu_B00707	COG3724	N-succinylarginine dihydrolase activity
vfu_B00708	COG1012	belongs to the aldehyde dehydrogenase family
vfu_B00713	COG4948	Mandelate Racemase Muconate Lactonizing
vfu_B00718	COG0583	DNA-binding transcription factor activity
vfu_B00721	COG0589	response to stress
vfu_B00723	COG3530	Putative quorum-sensing-regulated virulence factor
vfu_B00725	COG0579	oxidoreductase
vfu_B00729	COG2204	response regulator
vfu_B00730	COG2197	response regulator
vfu_B00731	COG1522	sequence-specific DNA binding
vfu_B00735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
vfu_B00739	COG0583	DNA-binding transcription factor activity
vfu_B00747	COG0251	oxidation-reduction process
vfu_B00758	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
vfu_B00759	COG0784	Response regulator, receiver
vfu_B00759	COG0835	chemotaxis
vfu_B00760	COG2315	Protein conserved in bacteria
vfu_B00761	COG1846	Transcriptional regulator
vfu_B00763	COG3706	GGDEF domain
vfu_B00774	COG1741	Belongs to the pirin family
vfu_B00775	COG0745	RESPONSE REGULATOR receiver
vfu_B00777	COG2205	protein histidine kinase activity
vfu_B00799	COG3501	Rhs element vgr protein
vfu_B00801	COG2814	Major facilitator Superfamily
vfu_B00803	COG3123	guanosine phosphorylase activity
vfu_B00805	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
vfu_B00806	COG0569	domain protein
vfu_B00807	COG0668	transmembrane transport
vfu_B00808	COG2211	Major facilitator Superfamily
vfu_B00809	COG0840	transmembrane signaling receptor activity
vfu_B00810	COG1067	ATP-dependent peptidase activity
vfu_B00812	COG4172	Belongs to the ABC transporter superfamily
vfu_B00813	COG0583	DNA-binding transcription factor activity
vfu_B00814	COG1620	l-lactate permease
vfu_B00815	COG1304	FMN binding
vfu_B00820	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
vfu_B00824	COG3152	Membrane
vfu_B00828	COG1403	HNH endonuclease
vfu_B00830	COG0519	Catalyzes the synthesis of GMP from XMP
vfu_B00831	COG0024	Methionine aminopeptidase
vfu_B00833	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_B00834	COG0583	DNA-binding transcription factor activity
vfu_B00837	COG1120	ATPase activity
vfu_B00838	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vfu_B00839	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vfu_B00840	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
vfu_B00841	COG4774	siderophore transport
vfu_B00845	COG3384	dioxygenase
vfu_B00846	COG0583	DNA-binding transcription factor activity
vfu_B00848	COG1342	Belongs to the UPF0251 family
vfu_B00849	COG0583	DNA-binding transcription factor activity
vfu_B00851	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
vfu_B00857	COG1917	Cupin 2, conserved barrel domain protein
vfu_B00857	COG2169	Transcriptional regulator
vfu_B00859	COG1301	dicarboxylic acid transport
vfu_B00860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
vfu_B00862	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
vfu_B00863	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
vfu_B00864	COG2259	Doxx family
vfu_B00866	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
vfu_B00867	COG0402	S-adenosylhomocysteine deaminase activity
vfu_B00873	COG0363	glucosamine-6-phosphate deaminase activity
vfu_B00876	COG0739	heme binding
vfu_B00877	COG2213	PTS system mannitol-specific
vfu_B00877	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
vfu_B00878	COG0246	Mannitol dehydrogenase
vfu_B00879	COG3722	fumarate hydratase activity
vfu_B00881	COG3284	Transcriptional regulator
vfu_B00882	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
vfu_B00883	COG1461	Dihydroxyacetone kinase
vfu_B00884	COG2376	Dihydroxyacetone kinase
vfu_B00887	COG1473	amidohydrolase
vfu_B00888	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
vfu_B00889	COG0583	DNA-binding transcription factor activity
vfu_B00891	COG2221	Nitrite and sulphite reductase 4Fe-4S
vfu_B00891	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
vfu_B00893	COG3302	dmso reductase anchor subunit
vfu_B00894	COG0437	4 iron, 4 sulfur cluster binding
vfu_B00895	COG0243	molybdopterin cofactor binding
vfu_B00897	COG0095	Lipoate-protein ligase
vfu_B00898	COG0443	Heat shock 70 kDa protein
vfu_B00901	COG2176	DNA-directed DNA polymerase activity
vfu_B00904	COG1309	transcriptional regulator
vfu_B00905	COG0492	ferredoxin-NADP+ reductase activity
vfu_B00906	COG3118	belongs to the thioredoxin family
vfu_B00907	COG3118	belongs to the thioredoxin family
vfu_B00909	COG2814	Major facilitator Superfamily
vfu_B00911	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
vfu_B00912	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
vfu_B00914	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
vfu_B00915	COG0583	DNA-binding transcription factor activity
vfu_B00916	COG1357	PFAM Pentapeptide repeats (8 copies)
vfu_B00919	COG1609	Transcriptional regulator
vfu_B00921	COG2814	Major facilitator Superfamily
vfu_B00923	COG4221	oxidoreductase activity
vfu_B00924	COG0583	DNA-binding transcription factor activity
vfu_B00928	COG3706	GGDEF domain
vfu_B00929	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vfu_B00931	COG3304	Inner membrane component domain
vfu_B00932	COG2329	Antibiotic biosynthesis monooxygenase
vfu_B00936	COG1609	Transcriptional regulator
vfu_B00936	COG2207	Transcriptional regulator
vfu_B00937	COG1335	isochorismatase
vfu_B00940	COG2910	NAD(P)H-binding
vfu_B00941	COG0583	DNA-binding transcription factor activity
vfu_B00944	COG1349	DNA-binding transcription factor activity
vfu_B00945	COG2084	Dehydrogenase
vfu_B00946	COG3395	kinase activity
vfu_B00947	COG0235	Class ii aldolase
vfu_B00948	COG3622	Belongs to the hyi family
vfu_B00949	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
vfu_B00950	COG2610	gluconate transmembrane transporter activity
vfu_B00951	COG1522	sequence-specific DNA binding
vfu_B00952	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
vfu_B00953	COG0724	RNA recognition motif
vfu_B00956	COG2226	methyltransferase
vfu_B00957	COG0583	DNA-binding transcription factor activity
vfu_B00959	COG0513	Belongs to the DEAD box helicase family
vfu_B00960	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
vfu_B00963	COG0840	transmembrane signaling receptor activity
vfu_B00970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
vfu_B00972	COG0259	pyridoxamine-phosphate oxidase activity
vfu_B00974	COG0745	RESPONSE REGULATOR receiver
vfu_B00977	COG2201	protein-glutamate methylesterase activity
vfu_B00978	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
vfu_B00979	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
vfu_B00980	COG0840	transmembrane signaling receptor activity
vfu_B00981	COG0835	chemotaxis
vfu_B00982	COG0835	chemotaxis
vfu_B00983	COG2198	Histidine kinase
vfu_B00983	COG0643	Histidine kinase
vfu_B00984	COG0745	RESPONSE REGULATOR receiver
vfu_B00986	COG1444	tRNA N-acetyltransferase activity
vfu_B00987	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
vfu_B00994	COG0217	transcriptional regulatory protein
vfu_B00997	COG2084	Dehydrogenase
vfu_B01000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
vfu_B01001	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
vfu_B01002	COG1845	cytochrome c oxidase, subunit III
vfu_B01003	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
vfu_B01004	COG0109	protoheme IX farnesyltransferase activity
vfu_B01006	COG2909	trisaccharide binding
vfu_B01007	COG0058	SHG alpha-glucan phosphorylase activity
vfu_B01008	COG1640	4-alpha-glucanotransferase
vfu_B01009	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
vfu_B01011	COG3501	Rhs element vgr protein
vfu_B01014	COG3788	relative of glutathione S-transferase, MAPEG superfamily
vfu_B01020	COG0471	metal ion transport
vfu_B01021	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
vfu_B01022	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
vfu_B01026	COG3033	Beta-eliminating lyase
vfu_B01029	COG2188	Transcriptional regulator
vfu_B01030	COG1131	(ABC) transporter
vfu_B01032	COG0840	transmembrane signaling receptor activity
vfu_B01035	COG3383	formate dehydrogenase (NAD+) activity
vfu_B01037	COG0671	phosphoesterase, PA-phosphatase related
vfu_B01039	COG1132	(ABC) transporter
vfu_B01041	COG4580	involved in the transport of maltose and maltodextrins
vfu_B01044	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
vfu_B01045	COG1162	GTPase activity
vfu_B01050	COG0786	glutamate:sodium symporter activity
vfu_B01057	COG1566	PFAM secretion protein HlyD family protein
vfu_B01059	COG3706	GGDEF domain
vfu_B01062	COG0813	purine-nucleoside phosphorylase activity
vfu_B01063	COG3272	Protein of unknown function (DUF1722)
vfu_B01064	COG0789	Transcriptional regulator
vfu_B01065	COG0415	Belongs to the DNA photolyase family
vfu_B01066	COG1388	LysM domain
vfu_B01066	COG1376	ErfK ybiS ycfS ynhG family protein
vfu_B01068	COG0513	Belongs to the DEAD box helicase family
vfu_B01070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
vfu_B01071	COG0573	inorganic phosphate transmembrane transporter activity
vfu_B01072	COG0581	inorganic phosphate transmembrane transporter activity
vfu_B01074	COG2199	diguanylate cyclase activity
vfu_B01077	COG0659	secondary active sulfate transmembrane transporter activity
vfu_B01080	COG0739	heme binding
vfu_B01081	COG5001	Diguanylate cyclase
vfu_B01082	COG0583	DNA-binding transcription factor activity
vfu_B01083	COG2814	Major facilitator Superfamily
vfu_B01089	COG1764	response to oxidative stress
vfu_B01090	COG1846	Transcriptional regulator
vfu_B01091	COG0179	Fumarylacetoacetate (FAA) hydrolase
vfu_B01096	COG1280	lysine exporter protein (LysE YggA)
vfu_B01098	COG1902	pentaerythritol trinitrate reductase activity
vfu_B01099	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
vfu_B01101	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
vfu_B01107	COG1612	heme a metabolic process
vfu_B01108	COG0109	protoheme IX farnesyltransferase activity
vfu_B01111	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
vfu_B01113	COG5002	protein histidine kinase activity
vfu_B01113	COG3447	MASE1 domain protein
vfu_B01113	COG5001	Diguanylate cyclase
vfu_B01118	COG1917	Cupin 2, conserved barrel domain protein
vfu_B01118	COG2207	Transcriptional regulator
vfu_B01121	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vfu_B01122	COG0697	spore germination
vfu_B01123	COG3477	response to acidic pH
vfu_B01124	COG3240	lipase activity
vfu_B01128	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
vfu_B01130	COG1349	DNA-binding transcription factor activity
vfu_B01131	COG0673	inositol 2-dehydrogenase activity
vfu_B01132	COG4702	Belongs to the UPF0303 family
vfu_B01135	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
vfu_B01141	COG3188	usher protein
vfu_B01143	COG1360	Flagellar Motor Protein
vfu_B01144	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
vfu_B01148	COG2814	Major facilitator Superfamily
vfu_B01149	COG0583	DNA-binding transcription factor activity
vfu_B01150	COG1902	pentaerythritol trinitrate reductase activity
vfu_B01151	COG0656	L-ascorbic acid biosynthetic process
vfu_B01152	COG4943	cyclic-guanylate-specific phosphodiesterase activity
vfu_B01154	COG3842	ATPase activity
vfu_B01160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
vfu_B01164	COG2130	NADP-dependent
vfu_B01165	COG1309	transcriptional regulator
vfu_B01166	COG0564	pseudouridine synthase activity
vfu_B01169	COG1846	Transcriptional regulator
vfu_B01191	COG3501	Rhs element vgr protein
vfu_B01195	COG1869	D-ribose catabolic process
vfu_B01196	COG1129	ABC transporter
vfu_B01197	COG1172	Belongs to the binding-protein-dependent transport system permease family
vfu_B01198	COG1879	ABC-type sugar transport system periplasmic component
vfu_B01199	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
vfu_B01200	COG1609	Transcriptional regulator
vfu_B01201	COG0583	DNA-binding transcription factor activity
vfu_B01202	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
vfu_B01204	COG0584	glycerophosphoryl diester phosphodiesterase
vfu_B01205	COG2271	Major facilitator Superfamily
vfu_B01206	COG5001	Diguanylate cyclase
vfu_B01206	COG3300	MHYT domain
vfu_B01211	COG2188	Transcriptional regulator
vfu_B01212	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
vfu_B01212	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
vfu_B01212	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
vfu_B01213	COG0383	alpha-mannosidase activity
vfu_B01214	COG1929	Belongs to the glycerate kinase type-1 family
vfu_B01216	COG0393	Putative heavy-metal-binding
vfu_B01217	COG0823	Involved in the tonB-independent uptake of proteins
vfu_B01218	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
vfu_B01219	COG0534	Mate efflux family protein
vfu_B01221	COG1653	transport
vfu_B01222	COG3842	ATPase activity
vfu_B01223	COG0395	ABC-type sugar transport system, permease component
vfu_B01224	COG1175	transmembrane transport
vfu_B01228	COG0840	transmembrane signaling receptor activity
vfu_B01230	COG0800	Aldolase
vfu_B01231	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
vfu_B01233	COG0235	Class ii aldolase
vfu_B01234	COG3254	rhamnose metabolic process
vfu_B01235	COG4806	L-rhamnose isomerase
vfu_B01236	COG1070	Carbohydrate kinase
vfu_B01237	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
vfu_B01243	COG1917	Cupin 2, conserved barrel domain protein
vfu_B01245	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_B01247	COG0517	IMP dehydrogenase activity
vfu_B01251	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
vfu_B01253	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
vfu_B01261	COG3842	ATPase activity
vfu_B01269	COG1349	DNA-binding transcription factor activity
vfu_B01273	COG2354	Protein conserved in bacteria
vfu_B01274	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
vfu_B01275	COG0418	dihydroorotase activity
vfu_B01276	COG3217	Mosc domain protein beta barrel domain protein
vfu_B01276	COG0633	Ferredoxin
vfu_B01282	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
vfu_B01283	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
vfu_B01285	COG0848	biopolymer transport protein
vfu_B01286	COG0811	peptide transport
vfu_B01287	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
vfu_B01289	COG3721	Heme iron utilization protein
vfu_B01290	COG0748	coenzyme F420 binding
vfu_B01292	COG0531	amino acid
vfu_B01293	COG1522	sequence-specific DNA binding
vfu_B01298	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
vfu_B01299	COG4943	cyclic-guanylate-specific phosphodiesterase activity
vfu_B01304	COG5002	protein histidine kinase activity
vfu_B01304	COG2205	protein histidine kinase activity
vfu_B01304	COG0784	Response regulator, receiver
vfu_B01309	COG1765	OsmC-like protein
vfu_B01311	COG0110	maltose O-acetyltransferase activity
vfu_B01318	COG3121	Chaperone
vfu_B01319	COG0579	oxidoreductase
vfu_B01323	COG0583	DNA-binding transcription factor activity
vfu_B01324	COG0798	PFAM Bile acid sodium symporter
vfu_B01325	COG0355	proton-transporting ATP synthase activity, rotational mechanism
vfu_B01327	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
vfu_B01338	COG1280	lysine exporter protein (LysE YggA)
vfu_B01340	COG0513	Belongs to the DEAD box helicase family
vfu_B01343	COG0840	transmembrane signaling receptor activity
vfu_B01346	COG2985	domain, Protein
vfu_B01348	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
vfu_B01357	COG3122	Protein conserved in bacteria
vfu_B01358	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
vfu_B01360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
vfu_B01361	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
vfu_B01361	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
vfu_B01364	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
vfu_B01366	COG0404	The glycine cleavage system catalyzes the degradation of glycine
vfu_B01367	COG3706	GGDEF domain
vfu_B01367	COG0745	RESPONSE REGULATOR receiver
vfu_B01368	COG3300	MHYT domain
vfu_B01368	COG5001	Diguanylate cyclase
vfu_B01369	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
vfu_B01378	COG0484	heat shock protein binding
vfu_B01380	COG1716	ATPase activity
vfu_B01380	COG5001	Diguanylate cyclase
vfu_B01381	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
vfu_B01383	COG4181	ATPase activity
vfu_B01385	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
vfu_B01387	COG1984	allophanate hydrolase subunit 2
vfu_B01389	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
vfu_B01391	COG5001	Diguanylate cyclase
vfu_B01391	COG3447	MASE1 domain protein
vfu_B01391	COG5002	protein histidine kinase activity
vfu_B01393	COG0840	transmembrane signaling receptor activity
vfu_B01394	COG0814	amino acid
vfu_B01396	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
vfu_B01397	COG0513	Belongs to the DEAD box helicase family
vfu_B01400	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
vfu_B01403	COG2425	protein containing a von Willebrand factor type A (vWA) domain
vfu_B01408	COG0840	transmembrane signaling receptor activity
vfu_B01411	COG0583	DNA-binding transcription factor activity
vfu_B01412	COG0697	spore germination
vfu_B01414	COG0406	alpha-ribazole phosphatase activity
vfu_B01415	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
vfu_B01416	COG1454	alcohol dehydrogenase
vfu_B01417	COG1609	Transcriptional regulator
vfu_B01417	COG2207	Transcriptional regulator
vfu_B01419	COG3634	alkyl hydroperoxide reductase activity
vfu_B01421	COG0450	alkyl hydroperoxide reductase
vfu_B01424	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
vfu_B01425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
vfu_B01426	COG1960	acyl-CoA dehydrogenase activity
vfu_B01428	COG0183	Belongs to the thiolase family
vfu_B01430	COG1960	acyl-CoA dehydrogenase activity
vfu_B01431	COG1024	Enoyl-CoA hydratase
vfu_B01432	COG1024	Enoyl-CoA hydratase
vfu_B01434	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_B01436	COG1028	Short-chain dehydrogenase reductase Sdr
vfu_B01438	COG2814	Major facilitator Superfamily
vfu_B01439	COG0653	protein targeting
vfu_B01442	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
vfu_B01446	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
vfu_B01446	COG0512	Glutamine amidotransferase of anthranilate synthase
vfu_B01447	COG1454	alcohol dehydrogenase
vfu_B01448	COG1464	Belongs to the NlpA lipoprotein family
vfu_B01453	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
vfu_B01454	COG0573	inorganic phosphate transmembrane transporter activity
vfu_B01456	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
vfu_B01457	COG0625	glutathione transferase activity
vfu_B01471	COG2721	sulfolactate sulfo-lyase activity
vfu_B01472	COG2721	sulfolactate sulfo-lyase activity
vfu_B01476	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
vfu_B01478	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
vfu_B01480	COG1280	lysine exporter protein (LysE YggA)
vfu_B01481	COG0400	carboxylic ester hydrolase activity
vfu_B01482	COG0435	Glutathione S-transferase
vfu_B01483	COG0583	DNA-binding transcription factor activity
vfu_B01484	COG4145	pantothenate transmembrane transporter activity
vfu_B01486	COG2423	ornithine cyclodeaminase activity
vfu_B01489	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
vfu_B01496	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
vfu_B01498	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
vfu_B01504	COG2207	Transcriptional regulator
vfu_B01508	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
vfu_B01510	COG0488	(ABC) transporter