locus-tag	class	description
IUJ52_00015	COG0784	Response regulator, receiver
IUJ52_00015	COG2205	protein histidine kinase activity
IUJ52_00020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IUJ52_00035	COG3106	COG3106 Predicted ATPase
IUJ52_00050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IUJ52_00070	COG0471	metal ion transport
IUJ52_00075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ52_00075	COG4191	Histidine kinase
IUJ52_00090	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IUJ52_00095	COG0778	Nitroreductase
IUJ52_00100	COG2991	Protein conserved in bacteria
IUJ52_00110	COG3250	beta-galactosidase activity
IUJ52_00120	COG1129	ABC transporter
IUJ52_00155	COG2169	Transcriptional regulator
IUJ52_00155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUJ52_00165	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IUJ52_00170	COG0372	Belongs to the citrate synthase family
IUJ52_00175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IUJ52_00195	COG1566	PFAM secretion protein HlyD family protein
IUJ52_00200	COG2814	Major facilitator Superfamily
IUJ52_00220	COG2195	Cleaves the N-terminal amino acid of tripeptides
IUJ52_00225	COG2200	EAL domain
IUJ52_00235	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
IUJ52_00245	COG0625	glutathione transferase activity
IUJ52_00265	COG2731	YhcH YjgK YiaL family protein
IUJ52_00280	COG1349	DNA-binding transcription factor activity
IUJ52_00285	COG3842	ATPase activity
IUJ52_00290	COG0395	ABC-type sugar transport system, permease component
IUJ52_00295	COG1175	transmembrane transport
IUJ52_00305	COG0039	L-malate dehydrogenase activity
IUJ52_00310	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ52_00315	COG3040	lipid binding
IUJ52_00325	COG0811	peptide transport
IUJ52_00330	COG0811	peptide transport
IUJ52_00335	COG0848	biopolymer transport protein
IUJ52_00355	COG4667	esterase of the alpha-beta hydrolase superfamily
IUJ52_00360	COG1793	dna ligase
IUJ52_00375	COG0307	riboflavin synthase, alpha
IUJ52_00385	COG3001	Fructosamine kinase
IUJ52_00395	COG0791	NLP P60 protein
IUJ52_00410	COG3148	PFAM DTW domain containing protein
IUJ52_00415	COG1940	carbohydrate kinase activity
IUJ52_00425	COG0303	'Molybdopterin
IUJ52_00430	COG0746	molybdenum cofactor guanylyltransferase activity
IUJ52_00435	COG3842	ATPase activity
IUJ52_00440	COG4662	Binding-protein-dependent transport system inner membrane component
IUJ52_00450	COG2204	response regulator
IUJ52_00455	COG3852	Histidine kinase
IUJ52_00470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IUJ52_00490	COG3381	protein complex oligomerization
IUJ52_00500	COG3383	formate dehydrogenase (NAD+) activity
IUJ52_00500	COG0243	molybdopterin cofactor binding
IUJ52_00505	COG0437	4 iron, 4 sulfur cluster binding
IUJ52_00520	COG0004	ammonium transporteR
IUJ52_00525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IUJ52_00530	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IUJ52_00540	COG1177	transmembrane transport
IUJ52_00550	COG3842	ATPase activity
IUJ52_00575	COG0589	response to stress
IUJ52_00580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUJ52_00595	COG2217	Heavy metal translocating P-type atpase
IUJ52_00605	COG2010	Cytochrome c
IUJ52_00620	COG3278	Belongs to the heme-copper respiratory oxidase family
IUJ52_00635	COG2205	protein histidine kinase activity
IUJ52_00635	COG0784	Response regulator, receiver
IUJ52_00655	COG3120	sequence-specific DNA binding
IUJ52_00660	COG1067	ATP-dependent peptidase activity
IUJ52_00665	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IUJ52_00680	COG0488	(ABC) transporter
IUJ52_00690	COG0116	Belongs to the methyltransferase superfamily
IUJ52_00690	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IUJ52_00700	COG0167	dihydroorotate dehydrogenase activity
IUJ52_00705	COG2902	Dehydrogenase
IUJ52_00715	COG0308	aminopeptidase N
IUJ52_00735	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IUJ52_00740	COG1956	GAF domain-containing protein
IUJ52_00745	COG1132	(ABC) transporter
IUJ52_00750	COG2995	paraquat-inducible protein a
IUJ52_00755	COG3008	intermembrane lipid transfer
IUJ52_00765	COG2996	Protein conserved in bacteria
IUJ52_00785	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ52_00790	COG1666	GTP binding
IUJ52_00795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ52_00810	COG1115	amino acid carrier protein
IUJ52_00835	COG3501	Rhs element vgr protein
IUJ52_00845	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
IUJ52_00850	COG4774	siderophore transport
IUJ52_00855	COG0583	DNA-binding transcription factor activity
IUJ52_00860	COG1120	ATPase activity
IUJ52_00865	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ52_00870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ52_00890	COG1414	Transcriptional regulator
IUJ52_00895	COG0583	DNA-binding transcription factor activity
IUJ52_00900	COG4638	Rieske (2fe-2S)
IUJ52_00930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ52_00965	COG1643	Atp-dependent helicase
IUJ52_00970	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IUJ52_01000	COG3706	GGDEF domain
IUJ52_01015	COG0443	Heat shock 70 kDa protein
IUJ52_01045	COG2999	glutathione oxidoreductase activity
IUJ52_01050	COG0657	acetylesterase activity
IUJ52_01055	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
IUJ52_01060	COG0243	molybdopterin cofactor binding
IUJ52_01065	COG3005	denitrification pathway
IUJ52_01070	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IUJ52_01075	COG0602	queuosine metabolic process
IUJ52_01080	COG0561	phosphatase activity
IUJ52_01090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ52_01095	COG4597	amino acid ABC transporter
IUJ52_01100	COG0765	amino acid transport
IUJ52_01105	COG1126	abc transporter atp-binding protein
IUJ52_01110	COG0670	Belongs to the BI1 family
IUJ52_01115	COG2920	part of a sulfur-relay system
IUJ52_01120	COG1254	Belongs to the acylphosphatase family
IUJ52_01125	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IUJ52_01130	COG3391	amine dehydrogenase activity
IUJ52_01140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IUJ52_01170	COG5002	protein histidine kinase activity
IUJ52_01175	COG0745	RESPONSE REGULATOR receiver
IUJ52_01195	COG0668	transmembrane transport
IUJ52_01255	COG2897	thiosulfate sulfurtransferase activity
IUJ52_01260	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IUJ52_01265	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
IUJ52_01270	COG0375	protein maturation
IUJ52_01275	COG0309	Hydrogenase expression formation protein (HypE)
IUJ52_01285	COG0298	carbon dioxide binding
IUJ52_01290	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
IUJ52_01300	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IUJ52_01305	COG3604	Transcriptional regulator
IUJ52_01315	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ52_01320	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
IUJ52_01330	COG3260	NADH ubiquinone oxidoreductase 20
IUJ52_01335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ52_01340	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
IUJ52_01340	COG3261	NADH dehydrogenase
IUJ52_01345	COG0650	Formate hydrogenlyase subunit 4
IUJ52_01350	COG0651	ATP synthesis coupled electron transport
IUJ52_01355	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ52_01365	COG1921	L-seryl-tRNASec selenium transferase activity
IUJ52_01375	COG0784	Response regulator, receiver
IUJ52_01375	COG0835	chemotaxis
IUJ52_01385	COG4565	transcriptional regulatory protein
IUJ52_01390	COG3290	protein histidine kinase activity
IUJ52_01405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ52_01425	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IUJ52_01430	COG3063	Type IV pilus biogenesis stability protein PilW
IUJ52_01445	COG1451	nucleotide metabolic process
IUJ52_01455	COG0583	DNA-binding transcription factor activity
IUJ52_01480	COG0110	maltose O-acetyltransferase activity
IUJ52_01495	COG1874	Beta-galactosidase
IUJ52_01505	COG3833	ABC-type maltose transport systems, permease component
IUJ52_01510	COG1175	transmembrane transport
IUJ52_01515	COG2182	Extracellular solute-binding protein
IUJ52_01525	COG1609	Transcriptional regulator
IUJ52_01570	COG4964	Belongs to the GSP D family
IUJ52_01640	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
IUJ52_01645	COG4139	cobalamin transport
IUJ52_01650	COG2988	succinylglutamate desuccinylase activity
IUJ52_01665	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
IUJ52_01670	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IUJ52_01675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ52_01685	COG1823	symporter activity
IUJ52_01690	COG2925	Exonuclease
IUJ52_01695	COG1380	Effector of murein hydrolase LrgA
IUJ52_01700	COG1346	cytolysis
IUJ52_01705	COG0295	cytidine deaminase activity
IUJ52_01710	COG5001	Diguanylate cyclase
IUJ52_01740	COG0500	methyltransferase
IUJ52_01750	COG0776	regulation of translation
IUJ52_01755	COG0072	phenylalanine-tRNA ligase activity
IUJ52_01755	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ52_01760	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IUJ52_01780	COG2133	pyrroloquinoline quinone binding
IUJ52_01810	COG0322	excinuclease ABC activity
IUJ52_01815	COG2197	response regulator
IUJ52_01820	COG0417	DNA replication proofreading
IUJ52_01830	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IUJ52_01835	COG3099	Belongs to the UPF0263 family
IUJ52_01850	COG1228	amidohydrolase
IUJ52_01855	COG0010	Belongs to the arginase family
IUJ52_01865	COG2986	histidine ammonia-lyase
IUJ52_01885	COG0277	FAD linked oxidase domain protein
IUJ52_01885	COG0247	lactate metabolic process
IUJ52_01900	COG2885	chlorophyll binding
IUJ52_01920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IUJ52_01925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ52_01935	COG2957	Belongs to the agmatine deiminase family
IUJ52_01945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ52_01950	COG1012	belongs to the aldehyde dehydrogenase family
IUJ52_01955	COG1396	sequence-specific DNA binding
IUJ52_01955	COG1917	Cupin 2, conserved barrel domain protein
IUJ52_01960	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IUJ52_01965	COG0174	glutamine synthetase
IUJ52_01970	COG1757	Na H antiporter
IUJ52_01985	COG0583	DNA-binding transcription factor activity
IUJ52_02000	COG1643	Atp-dependent helicase
IUJ52_02005	COG0281	malic enzyme
IUJ52_02015	COG0583	DNA-binding transcription factor activity
IUJ52_02030	COG0640	Transcriptional regulator
IUJ52_02055	COG2949	membrane
IUJ52_02085	COG0492	ferredoxin-NADP+ reductase activity
IUJ52_02090	COG4988	ABC transporter
IUJ52_02095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IUJ52_02110	COG1187	pseudouridine synthase activity
IUJ52_02115	COG0009	L-threonylcarbamoyladenylate synthase
IUJ52_02125	COG0800	Aldolase
IUJ52_02130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ52_02135	COG4145	pantothenate transmembrane transporter activity
IUJ52_02145	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
IUJ52_02155	COG1737	Transcriptional regulator
IUJ52_02155	COG0837	glucose binding
IUJ52_02160	COG0613	PHP domain protein
IUJ52_02170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IUJ52_02175	COG0512	Glutamine amidotransferase of anthranilate synthase
IUJ52_02180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IUJ52_02185	COG0135	phosphoribosylanthranilate isomerase activity
IUJ52_02185	COG0134	indole-3-glycerol-phosphate synthase activity
IUJ52_02190	COG0133	tryptophan synthase activity
IUJ52_02195	COG0159	tryptophan synthase activity
IUJ52_02200	COG1301	dicarboxylic acid transport
IUJ52_02215	COG2350	Protein conserved in bacteria
IUJ52_02230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IUJ52_02240	COG1360	Flagellar Motor Protein
IUJ52_02245	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IUJ52_02280	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IUJ52_02285	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IUJ52_02290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IUJ52_02295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IUJ52_02325	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IUJ52_02335	COG1677	Flagellar hook-basal body complex protein FliE
IUJ52_02360	COG1706	bacterial-type flagellum-dependent cell motility
IUJ52_02365	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IUJ52_02370	COG4786	Flagellar basal body rod
IUJ52_02380	COG1749	Flagellar hook protein flgE
IUJ52_02385	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IUJ52_02390	COG1558	bacterial-type flagellum-dependent cell motility
IUJ52_02395	COG1815	bacterial-type flagellum-dependent cell motility
IUJ52_02405	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IUJ52_02440	COG0583	DNA-binding transcription factor activity
IUJ52_02455	COG0612	Peptidase, M16
IUJ52_02470	COG2200	EAL domain
IUJ52_02470	COG2771	luxR family
IUJ52_02475	COG0840	transmembrane signaling receptor activity
IUJ52_02490	COG0346	lactoylglutathione lyase activity
IUJ52_02500	COG0488	(ABC) transporter
IUJ52_02505	COG1032	radical SAM domain protein
IUJ52_02510	COG2211	Major facilitator Superfamily
IUJ52_02515	COG3940	Belongs to the glycosyl hydrolase 43 family
IUJ52_02530	COG1053	succinate dehydrogenase
IUJ52_02535	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IUJ52_02545	COG4191	Histidine kinase
IUJ52_02545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ52_02560	COG3070	regulator of competence-specific genes
IUJ52_02570	COG2431	L-lysine efflux transmembrane transporter activity
IUJ52_02580	COG0076	glutamate decarboxylase activity
IUJ52_02585	COG1737	Transcriptional regulator
IUJ52_02595	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IUJ52_02605	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IUJ52_02610	COG1960	acyl-CoA dehydrogenase activity
IUJ52_02640	COG0700	Nucleoside recognition
IUJ52_02645	COG3366	ferrous iron transmembrane transporter activity
IUJ52_02665	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ52_02670	COG3716	PTS system mannose fructose sorbose family IID component
IUJ52_02675	COG3715	PTS system
IUJ52_02680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ52_02685	COG2222	sugar isomerase
IUJ52_02695	COG1349	DNA-binding transcription factor activity
IUJ52_02700	COG1349	DNA-binding transcription factor activity
IUJ52_02820	COG0582	viral genome integration into host DNA
IUJ52_02835	COG5002	protein histidine kinase activity
IUJ52_02835	COG0784	Response regulator, receiver
IUJ52_02845	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IUJ52_02850	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
IUJ52_02855	COG2885	chlorophyll binding
IUJ52_02860	COG0823	Involved in the tonB-independent uptake of proteins
IUJ52_02875	COG0811	peptide transport
IUJ52_02880	COG0824	Thioesterase
IUJ52_02890	COG4890	Cyd operon protein YbgT
IUJ52_02895	COG1294	oxidase, subunit
IUJ52_02900	COG1271	oxidase subunit
IUJ52_02905	COG2255	four-way junction helicase activity
IUJ52_02910	COG0632	four-way junction helicase activity
IUJ52_02915	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IUJ52_02920	COG0215	cysteine-tRNA ligase activity
IUJ52_02925	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IUJ52_02930	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ52_02935	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IUJ52_02940	COG3012	SEC-C Motif Domain Protein
IUJ52_02945	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IUJ52_02950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ52_02955	COG1199	ATP-dependent helicase activity
IUJ52_02960	COG3923	Primosomal replication protein n
IUJ52_02975	COG0708	Exodeoxyribonuclease III
IUJ52_02980	COG4160	amino acid transport
IUJ52_03005	COG1882	Formate acetyltransferase
IUJ52_03020	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IUJ52_03030	COG3013	Belongs to the UPF0304 family
IUJ52_03035	COG3713	MltA-interacting MipA family protein
IUJ52_03040	COG2766	serine protein kinase
IUJ52_03045	COG2718	Belongs to the UPF0229 family
IUJ52_03050	COG2719	SpoVR family
IUJ52_03055	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IUJ52_03065	COG1663	tetraacyldisaccharide 4'-kinase activity
IUJ52_03070	COG1132	(ABC) transporter
IUJ52_03075	COG2333	competence protein COMEC
IUJ52_03075	COG0658	competence protein
IUJ52_03085	COG4591	ABC-type transport system involved in lipoprotein release permease component
IUJ52_03090	COG1136	(ABC) transporter
IUJ52_03095	COG4591	ABC-type transport system involved in lipoprotein release permease component
IUJ52_03105	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IUJ52_03120	COG1252	NADH dehydrogenase
IUJ52_03125	COG3150	esterase
IUJ52_03150	COG0537	adenosine 5'-monophosphoramidase activity
IUJ52_03165	COG2186	Transcriptional regulator
IUJ52_03170	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IUJ52_03175	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IUJ52_03180	COG1674	ftsk spoiiie
IUJ52_03185	COG1522	sequence-specific DNA binding
IUJ52_03190	COG0686	Belongs to the AlaDH PNT family
IUJ52_03200	COG0583	DNA-binding transcription factor activity
IUJ52_03220	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IUJ52_03225	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
IUJ52_03230	COG0776	regulation of translation
IUJ52_03235	COG0539	negative regulation of cytoplasmic translation
IUJ52_03240	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IUJ52_03245	COG1555	photosystem II stabilization
IUJ52_03250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ52_03255	COG0776	regulation of translation
IUJ52_03260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IUJ52_03265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IUJ52_03275	COG0544	peptidyl-prolyl cis-trans isomerase activity
IUJ52_03285	COG4191	Histidine kinase
IUJ52_03290	COG2204	response regulator
IUJ52_03295	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ52_03300	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ52_03305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ52_03330	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IUJ52_03335	COG1760	l-serine dehydratase
IUJ52_03345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IUJ52_03345	COG3153	acetyltransferase
IUJ52_03355	COG3300	MHYT domain
IUJ52_03355	COG5001	Diguanylate cyclase
IUJ52_03365	COG4589	Belongs to the CDS family
IUJ52_03400	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IUJ52_03405	COG0732	type I restriction modification DNA specificity domain
IUJ52_03420	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IUJ52_03425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IUJ52_03435	COG2951	lytic endotransglycosylase activity
IUJ52_03440	COG3100	YcgL domain-containing protein
IUJ52_03445	COG0850	regulation of cytokinetic process
IUJ52_03450	COG2894	cell division
IUJ52_03455	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IUJ52_03465	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
IUJ52_03470	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ52_03475	COG2267	carboxylic ester hydrolase activity
IUJ52_03490	COG1214	PFAM Peptidase M22, glycoprotease
IUJ52_03495	COG1199	ATP-dependent helicase activity
IUJ52_03505	COG0788	formyltetrahydrofolate deformylase activity
IUJ52_03510	COG1902	pentaerythritol trinitrate reductase activity
IUJ52_03510	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ52_03515	COG0616	signal peptide processing
IUJ52_03520	COG0252	asparaginase activity
IUJ52_03525	COG3139	Protein of unknown function (DUF1315)
IUJ52_03535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ52_03540	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IUJ52_03545	COG0676	glucose-6-phosphate 1-epimerase activity
IUJ52_03550	COG2226	methyltransferase
IUJ52_03565	COG2983	Belongs to the UPF0260 family
IUJ52_03575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IUJ52_03580	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IUJ52_03585	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IUJ52_03595	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IUJ52_03600	COG2832	Protein of unknown function (DUF454)
IUJ52_03605	COG0745	RESPONSE REGULATOR receiver
IUJ52_03610	COG0583	DNA-binding transcription factor activity
IUJ52_03615	COG0778	Nitroreductase
IUJ52_03620	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ52_03620	COG1024	Enoyl-CoA hydratase
IUJ52_03625	COG0183	Belongs to the thiolase family
IUJ52_03640	COG2067	long-chain fatty acid transport protein
IUJ52_03645	COG2067	long-chain fatty acid transport protein
IUJ52_03650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IUJ52_03665	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IUJ52_03670	COG2982	Protein involved in outer membrane biogenesis
IUJ52_03675	COG0572	uridine kinase
IUJ52_03685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ52_03685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ52_03695	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IUJ52_03705	COG0517	IMP dehydrogenase activity
IUJ52_03705	COG0617	tRNA 3'-terminal CCA addition
IUJ52_03705	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IUJ52_03710	COG3706	GGDEF domain
IUJ52_03715	COG0314	molybdopterin synthase activity
IUJ52_03720	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
IUJ52_03725	COG0315	cyclic pyranopterin monophosphate synthase activity
IUJ52_03730	COG0521	Mo-molybdopterin cofactor biosynthetic process
IUJ52_03735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IUJ52_03740	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IUJ52_03745	COG2198	Histidine kinase
IUJ52_03750	COG2204	response regulator
IUJ52_03755	COG0556	nucleotide-excision repair
IUJ52_03765	COG1882	Formate acetyltransferase
IUJ52_03770	COG4657	Part of a membrane complex involved in electron transport
IUJ52_03775	COG2878	Part of a membrane complex involved in electron transport
IUJ52_03780	COG4656	Part of a membrane complex involved in electron transport
IUJ52_03785	COG4658	electron transport chain
IUJ52_03790	COG4659	FMN binding
IUJ52_03795	COG4660	Part of a membrane complex involved in electron transport
IUJ52_03800	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IUJ52_03805	COG0346	lactoylglutathione lyase activity
IUJ52_03820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IUJ52_03825	COG2056	Na+-H+ antiporter family
IUJ52_03830	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IUJ52_03835	COG1286	toxin biosynthetic process
IUJ52_03840	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IUJ52_03845	COG0285	dihydrofolate synthase activity
IUJ52_03850	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IUJ52_03855	COG0101	tRNA pseudouridine synthase activity
IUJ52_03870	COG1263	PTS System
IUJ52_03870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ52_03870	COG2190	(PTS) system
IUJ52_03875	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
IUJ52_03880	COG1940	carbohydrate kinase activity
IUJ52_03880	COG1846	Transcriptional regulator
IUJ52_03885	COG4651	solute:proton antiporter activity
IUJ52_03885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUJ52_03890	COG0367	asparagine synthase
IUJ52_03905	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IUJ52_03915	COG0326	Molecular chaperone. Has ATPase activity
IUJ52_03920	COG3710	Transcriptional regulator
IUJ52_03935	COG0622	Phosphoesterase
IUJ52_03960	COG1090	epimerase
IUJ52_03965	COG0300	oxidoreductase activity
IUJ52_03970	COG3118	belongs to the thioredoxin family
IUJ52_03975	COG0330	HflC and HflK could
IUJ52_03985	COG0789	Transcriptional regulator
IUJ52_04000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IUJ52_04005	COG3115	cell septum assembly
IUJ52_04010	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
IUJ52_04015	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IUJ52_04020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ52_04030	COG2190	(PTS) system
IUJ52_04035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ52_04040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IUJ52_04045	COG1702	phosphate starvation-inducible protein PhoH
IUJ52_04050	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IUJ52_04055	COG4535	Mg2 and Co2 transporter CorC
IUJ52_04060	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IUJ52_04065	COG2888	peptidyl-tyrosine sulfation
IUJ52_04070	COG0495	leucyl-tRNA aminoacylation
IUJ52_04075	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
IUJ52_04080	COG1466	dna polymerase III delta subunit
IUJ52_04085	COG0799	negative regulation of ribosome biogenesis
IUJ52_04090	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IUJ52_04095	COG0768	penicillin binding
IUJ52_04100	COG0772	Belongs to the SEDS family
IUJ52_04105	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IUJ52_04110	COG1686	Belongs to the peptidase S11 family
IUJ52_04115	COG2921	Belongs to the UPF0250 family
IUJ52_04120	COG0321	lipoyl(octanoyl) transferase activity
IUJ52_04125	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IUJ52_04135	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IUJ52_04145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ52_04150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ52_04175	COG0366	Alpha amylase catalytic
IUJ52_04180	COG1263	PTS System
IUJ52_04180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ52_04195	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IUJ52_04200	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IUJ52_04205	COG2011	ABC-type metal ion transport system permease component
IUJ52_04210	COG1464	Belongs to the NlpA lipoprotein family
IUJ52_04215	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
IUJ52_04225	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IUJ52_04225	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IUJ52_04240	COG1611	Belongs to the LOG family
IUJ52_04245	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IUJ52_04255	COG2363	Small membrane protein
IUJ52_04265	COG0583	DNA-binding transcription factor activity
IUJ52_04270	COG0301	tRNA thio-modification
IUJ52_04270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ52_04280	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IUJ52_04285	COG1722	exodeoxyribonuclease VII activity
IUJ52_04290	COG0142	geranyltranstransferase activity
IUJ52_04295	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IUJ52_04300	COG0564	pseudouridine synthase activity
IUJ52_04305	COG3098	single-species biofilm formation
IUJ52_04330	COG1671	Belongs to the UPF0178 family
IUJ52_04335	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IUJ52_04340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IUJ52_04345	COG0254	rRNA binding
IUJ52_04350	COG1720	tRNA m6t6A37 methyltransferase activity
IUJ52_04355	COG0442	prolyl-tRNA aminoacylation
IUJ52_04380	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IUJ52_04380	COG0047	phosphoribosylformylglycinamidine synthase activity
IUJ52_04385	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IUJ52_04395	COG0583	DNA-binding transcription factor activity
IUJ52_04405	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IUJ52_04410	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IUJ52_04440	COG0484	heat shock protein binding
IUJ52_04445	COG0443	Heat shock 70 kDa protein
IUJ52_04455	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IUJ52_04460	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IUJ52_04465	COG0497	DNA recombination
IUJ52_04470	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ52_04475	COG2914	Belongs to the UPF0125 (RnfH) family
IUJ52_04480	COG2867	negative regulation of translational initiation
IUJ52_04485	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IUJ52_04495	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
IUJ52_04495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ52_04505	COG0583	DNA-binding transcription factor activity
IUJ52_04520	COG1115	amino acid carrier protein
IUJ52_04545	COG3121	Chaperone
IUJ52_04550	COG3188	usher protein
IUJ52_04560	COG3710	Transcriptional regulator
IUJ52_04565	COG1584	GPR1 FUN34 yaaH family protein
IUJ52_04585	COG3833	ABC-type maltose transport systems, permease component
IUJ52_04590	COG1175	transmembrane transport
IUJ52_04595	COG2182	Extracellular solute-binding protein
IUJ52_04605	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ52_04615	COG3842	ATPase activity
IUJ52_04670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUJ52_04670	COG4651	solute:proton antiporter activity
IUJ52_04675	COG0589	response to stress
IUJ52_04710	COG2203	Gaf domain
IUJ52_04710	COG3706	GGDEF domain
IUJ52_04710	COG4251	negative regulation of phosphorylation
IUJ52_04710	COG5001	Diguanylate cyclase
IUJ52_04735	COG0582	viral genome integration into host DNA
IUJ52_04740	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ52_04740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUJ52_04745	COG0517	IMP dehydrogenase activity
IUJ52_04745	COG0516	GMP reductase activity
IUJ52_04750	COG1570	exodeoxyribonuclease VII activity
IUJ52_04765	COG1160	GTP binding
IUJ52_04770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ52_04775	COG2976	Protein conserved in bacteria
IUJ52_04780	COG0124	histidyl-tRNA synthetase
IUJ52_04785	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IUJ52_04800	COG0105	UTP biosynthetic process
IUJ52_04805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IUJ52_04810	COG2975	iron-sulfur cluster assembly
IUJ52_04815	COG0633	Ferredoxin
IUJ52_04820	COG0443	Heat shock 70 kDa protein
IUJ52_04835	COG0822	iron-sulfur transferase activity
IUJ52_04840	COG1104	cysteine desulfurase activity
IUJ52_04845	COG1959	2 iron, 2 sulfur cluster binding
IUJ52_04850	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
IUJ52_04855	COG0483	inositol monophosphate 1-phosphatase activity
IUJ52_04860	COG1335	isochorismatase
IUJ52_04865	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ52_04870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ52_04875	COG1862	Preprotein translocase
IUJ52_04885	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IUJ52_04890	COG0517	IMP dehydrogenase activity
IUJ52_04905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IUJ52_04910	COG0583	DNA-binding transcription factor activity
IUJ52_04915	COG0450	alkyl hydroperoxide reductase
IUJ52_04920	COG3142	Participates in the control of copper homeostasis
IUJ52_04930	COG0704	Plays a role in the regulation of phosphate uptake
IUJ52_04935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IUJ52_04940	COG0581	inorganic phosphate transmembrane transporter activity
IUJ52_04945	COG0573	inorganic phosphate transmembrane transporter activity
IUJ52_04950	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IUJ52_04955	COG0248	Ppx GppA phosphatase
IUJ52_04965	COG5002	protein histidine kinase activity
IUJ52_04970	COG0745	RESPONSE REGULATOR receiver
IUJ52_04980	COG0826	peptidase U32
IUJ52_04985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ52_04990	COG0477	Major facilitator Superfamily
IUJ52_05000	COG1595	DNA-templated transcription, initiation
IUJ52_05010	COG3248	Nucleoside-binding outer membrane protein
IUJ52_05015	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IUJ52_05020	COG0693	protein deglycase activity
IUJ52_05025	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IUJ52_05030	COG2166	iron-sulfur cluster assembly
IUJ52_05035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IUJ52_05040	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IUJ52_05050	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IUJ52_05050	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IUJ52_05060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IUJ52_05065	COG1074	ATP-dependent DNA helicase activity
IUJ52_05070	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IUJ52_05080	COG0583	DNA-binding transcription factor activity
IUJ52_05085	COG3141	response to X-ray
IUJ52_05090	COG2171	N-acyltransferase activity
IUJ52_05095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IUJ52_05125	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ52_05130	COG2017	converts alpha-aldose to the beta-anomer
IUJ52_05135	COG2059	Chromate
IUJ52_05190	COG4964	Belongs to the GSP D family
IUJ52_05220	COG1022	Amp-dependent synthetase and ligase
IUJ52_05225	COG0583	DNA-binding transcription factor activity
IUJ52_05235	COG0583	DNA-binding transcription factor activity
IUJ52_05240	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IUJ52_05245	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IUJ52_05255	COG0560	Phosphoserine phosphatase
IUJ52_05265	COG0813	purine-nucleoside phosphorylase activity
IUJ52_05270	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
IUJ52_05275	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IUJ52_05280	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IUJ52_05290	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IUJ52_05295	COG0084	hydrolase, TatD family'
IUJ52_05305	COG3022	response to hydroperoxide
IUJ52_05310	COG1115	amino acid carrier protein
IUJ52_05325	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IUJ52_05340	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
IUJ52_05345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IUJ52_05350	COG0083	homoserine kinase activity
IUJ52_05365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ52_05375	COG0745	RESPONSE REGULATOR receiver
IUJ52_05385	COG5002	protein histidine kinase activity
IUJ52_05385	COG2198	Histidine kinase
IUJ52_05385	COG0784	Response regulator, receiver
IUJ52_05390	COG4251	negative regulation of phosphorylation
IUJ52_05390	COG5001	Diguanylate cyclase
IUJ52_05390	COG2203	Gaf domain
IUJ52_05390	COG3706	GGDEF domain
IUJ52_05395	COG1242	4 iron, 4 sulfur cluster binding
IUJ52_05400	COG0069	glutamate synthase activity
IUJ52_05400	COG0067	glutamate synthase
IUJ52_05400	COG0070	glutamate synthase
IUJ52_05410	COG0070	glutamate synthase
IUJ52_05410	COG0069	glutamate synthase activity
IUJ52_05410	COG0067	glutamate synthase
IUJ52_05415	COG0493	'glutamate synthase
IUJ52_05425	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IUJ52_05435	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IUJ52_05440	COG2860	membrane
IUJ52_05460	COG0583	DNA-binding transcription factor activity
IUJ52_05465	COG0730	response to heat
IUJ52_05470	COG3479	Phenolic acid decarboxylase
IUJ52_05480	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IUJ52_05485	COG0505	Belongs to the CarA family
IUJ52_05490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IUJ52_05495	COG0494	nUDIX hydrolase
IUJ52_05500	COG0653	protein targeting
IUJ52_05510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IUJ52_05515	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IUJ52_05520	COG0849	cell division
IUJ52_05525	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IUJ52_05530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUJ52_05535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IUJ52_05540	COG0772	Belongs to the SEDS family
IUJ52_05545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IUJ52_05555	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IUJ52_05560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IUJ52_05565	COG0768	penicillin binding
IUJ52_05570	COG3116	cell division
IUJ52_05585	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IUJ52_05590	COG3107	peptidoglycan biosynthetic process
IUJ52_05595	COG0792	nuclease activity
IUJ52_05600	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IUJ52_05605	COG2823	Periplasmic or secreted lipoprotein
IUJ52_05610	COG2969	positive regulation of protein catabolic process
IUJ52_05615	COG0625	glutathione transferase activity
IUJ52_05620	COG2857	Cytochrome c1
IUJ52_05625	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IUJ52_05630	COG0723	plastoquinol--plastocyanin reductase activity
IUJ52_05640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IUJ52_05645	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IUJ52_05650	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IUJ52_05655	COG3105	Protein conserved in bacteria
IUJ52_05660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ52_05665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ52_05670	COG0335	large ribosomal subunit rRNA binding
IUJ52_05675	COG0336	Belongs to the RNA methyltransferase TrmD family
IUJ52_05680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IUJ52_05690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IUJ52_05695	COG4137	Cytochrome C assembly protein
IUJ52_05700	COG4536	flavin adenine dinucleotide binding
IUJ52_05705	COG1854	S-ribosylhomocysteine lyase activity
IUJ52_05715	COG2918	glutathione biosynthetic process
IUJ52_05720	COG0612	Peptidase, M16
IUJ52_05725	COG1238	metal cluster binding
IUJ52_05735	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IUJ52_05740	COG5016	pyruvate
IUJ52_05740	COG0511	ligase activity, forming carbon-carbon bonds
IUJ52_05745	COG3630	sodium ion export across plasma membrane
IUJ52_05795	COG0527	aspartate kinase activity
IUJ52_05800	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IUJ52_05805	COG2137	regulation of response to DNA damage stimulus
IUJ52_05810	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IUJ52_05815	COG1546	Belongs to the CinA family
IUJ52_05820	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IUJ52_05825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IUJ52_05830	COG4942	peptidase
IUJ52_05830	COG1388	LysM domain
IUJ52_05835	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IUJ52_05840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IUJ52_05845	COG0585	pseudouridine synthase activity
IUJ52_05855	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IUJ52_05860	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IUJ52_05865	COG1968	undecaprenyl-diphosphatase activity
IUJ52_05870	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IUJ52_05875	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IUJ52_05880	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IUJ52_05890	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IUJ52_05895	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IUJ52_05900	COG1610	YqeY-like protein
IUJ52_05905	COG0358	DNA primase activity
IUJ52_05920	COG0582	viral genome integration into host DNA
IUJ52_05960	COG3339	Conserved Protein
IUJ52_05975	COG2003	Belongs to the UPF0758 family
IUJ52_06040	COG2239	Acts as a magnesium transporter
IUJ52_06065	COG0583	DNA-binding transcription factor activity
IUJ52_06070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IUJ52_06075	COG1349	DNA-binding transcription factor activity
IUJ52_06100	COG1279	arginine transmembrane transporter activity
IUJ52_06110	COG0668	transmembrane transport
IUJ52_06115	COG0191	fructose-bisphosphate aldolase activity
IUJ52_06120	COG0126	phosphoglycerate kinase activity
IUJ52_06125	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IUJ52_06130	COG4771	TonB-dependent receptor
IUJ52_06135	COG0583	DNA-binding transcription factor activity
IUJ52_06140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IUJ52_06145	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IUJ52_06160	COG2356	endonuclease I
IUJ52_06165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IUJ52_06170	COG0189	ligase activity
IUJ52_06175	COG1678	Uncharacterized ACR, COG1678
IUJ52_06180	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IUJ52_06195	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IUJ52_06200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IUJ52_06205	COG0762	integral membrane protein
IUJ52_06210	COG1872	DUF167
IUJ52_06220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IUJ52_06225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUJ52_06230	COG2066	Belongs to the glutaminase family
IUJ52_06235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IUJ52_06240	COG1194	a g-specific adenine glycosylase
IUJ52_06245	COG1120	ATPase activity
IUJ52_06250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ52_06255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IUJ52_06265	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IUJ52_06270	COG0741	lytic transglycosylase activity
IUJ52_06320	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IUJ52_06325	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IUJ52_06330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ52_06335	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IUJ52_06340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IUJ52_06345	COG2967	ApaG domain
IUJ52_06350	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IUJ52_06360	COG3610	response to peptide
IUJ52_06365	COG2966	Psort location CytoplasmicMembrane, score
IUJ52_06370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IUJ52_06380	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IUJ52_06385	COG0142	geranyltranstransferase activity
IUJ52_06390	COG0531	amino acid
IUJ52_06395	COG0039	L-malate dehydrogenase activity
IUJ52_06400	COG1438	arginine binding
IUJ52_06415	COG0589	response to stress
IUJ52_06435	COG0312	modulator of DNA gyrase
IUJ52_06440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IUJ52_06445	COG3164	Protein of unknown function
IUJ52_06450	COG1530	ribonuclease E activity
IUJ52_06455	COG0424	maF-like protein
IUJ52_06460	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IUJ52_06465	COG1792	Involved in formation and maintenance of cell shape
IUJ52_06470	COG1077	Cell shape determining protein MreB Mrl
IUJ52_06500	COG2165	general secretion pathway protein
IUJ52_06505	COG2165	general secretion pathway protein
IUJ52_06515	COG1459	type II secretion system
IUJ52_06520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUJ52_06530	COG3267	Type II secretory pathway component ExeA
IUJ52_06530	COG3409	Peptidoglycan-binding domain 1 protein
IUJ52_06555	COG2199	diguanylate cyclase activity
IUJ52_06555	COG2200	EAL domain
IUJ52_06560	COG0629	single-stranded DNA binding
IUJ52_06575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IUJ52_06585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IUJ52_06590	COG0527	aspartate kinase activity
IUJ52_06595	COG0646	methionine synthase
IUJ52_06595	COG1410	methionine synthase
IUJ52_06655	COG0175	sulfate reduction
IUJ52_06665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IUJ52_06685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IUJ52_06690	COG0735	belongs to the Fur family
IUJ52_06700	COG0166	Belongs to the GPI family
IUJ52_06710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IUJ52_06725	COG0359	binds to the 23S rRNA
IUJ52_06735	COG2965	DNA replication, synthesis of RNA primer
IUJ52_06740	COG0360	Binds together with S18 to 16S ribosomal RNA
IUJ52_06750	COG2906	2 iron, 2 sulfur cluster binding
IUJ52_06760	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IUJ52_06765	COG0049	tRNA binding
IUJ52_06775	COG2168	tRNA wobble position uridine thiolation
IUJ52_06780	COG2923	Belongs to the DsrF TusC family
IUJ52_06790	COG2964	Protein conserved in bacteria
IUJ52_06795	COG0545	Peptidyl-prolyl cis-trans isomerase
IUJ52_06805	COG2900	Belongs to the SlyX family
IUJ52_06810	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IUJ52_06815	COG0330	HflC and HflK could
IUJ52_06820	COG0330	HflC and HflK could
IUJ52_06825	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IUJ52_06835	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IUJ52_06840	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IUJ52_06850	COG0802	atpase or kinase
IUJ52_06855	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IUJ52_06910	COG1162	GTPase activity
IUJ52_06915	COG0688	phosphatidylethanolamine metabolic process
IUJ52_06920	COG0471	metal ion transport
IUJ52_06920	COG0490	domain, Protein
IUJ52_06925	COG0840	transmembrane signaling receptor activity
IUJ52_06935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IUJ52_06940	COG4942	peptidase
IUJ52_06955	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IUJ52_06960	COG2816	NAD+ diphosphatase activity
IUJ52_06965	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
IUJ52_06970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IUJ52_06975	COG0085	RNA polymerase activity
IUJ52_06980	COG0222	ribosome binding
IUJ52_06985	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IUJ52_07000	COG0250	Participates in transcription elongation, termination and antitermination
IUJ52_07005	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IUJ52_07035	COG1072	(Pantothenic acid kinase))
IUJ52_07045	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IUJ52_07055	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ52_07100	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IUJ52_07115	COG3118	belongs to the thioredoxin family
IUJ52_07120	COG0513	Belongs to the DEAD box helicase family
IUJ52_07125	COG0248	Ppx GppA phosphatase
IUJ52_07130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ52_07130	COG2205	protein histidine kinase activity
IUJ52_07130	COG0784	Response regulator, receiver
IUJ52_07130	COG2198	Histidine kinase
IUJ52_07135	COG2814	Major facilitator Superfamily
IUJ52_07150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ52_07155	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IUJ52_07160	COG0511	ligase activity, forming carbon-carbon bonds
IUJ52_07165	COG0439	Biotin carboxylase
IUJ52_07170	COG2264	protein methyltransferase activity
IUJ52_07175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IUJ52_07180	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IUJ52_07185	COG0840	transmembrane signaling receptor activity
IUJ52_07190	COG0789	Transcriptional regulator
IUJ52_07200	COG0138	bifunctional purine biosynthesis protein purh
IUJ52_07205	COG0151	Belongs to the GarS family
IUJ52_07215	COG0776	regulation of translation
IUJ52_07220	COG1253	flavin adenine dinucleotide binding
IUJ52_07225	COG0668	transmembrane transport
IUJ52_07230	COG3068	Protein conserved in bacteria
IUJ52_07235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ52_07240	COG1573	uracil-dna glycosylase
IUJ52_07260	COG0741	lytic transglycosylase activity
IUJ52_07275	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
IUJ52_07280	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IUJ52_07285	COG3562	capsule polysaccharide
IUJ52_07290	COG0438	transferase activity, transferring glycosyl groups
IUJ52_07295	COG0438	transferase activity, transferring glycosyl groups
IUJ52_07305	COG2843	Capsule synthesis protein
IUJ52_07340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IUJ52_07350	COG1215	transferase activity, transferring glycosyl groups
IUJ52_07360	COG1216	Glycosyl transferase, family 2
IUJ52_07370	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IUJ52_07375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IUJ52_07415	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ52_07420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ52_07430	COG1560	Kdo2-lipid A biosynthetic process
IUJ52_07440	COG0859	PFAM glycosyl transferase family 9
IUJ52_07445	COG0859	PFAM glycosyl transferase family 9
IUJ52_07450	COG1519	Transferase
IUJ52_07455	COG0438	transferase activity, transferring glycosyl groups
IUJ52_07460	COG3642	lipopolysaccharide core region biosynthetic process
IUJ52_07465	COG0859	PFAM glycosyl transferase family 9
IUJ52_07470	COG0463	Glycosyl transferase, family 2
IUJ52_07475	COG0438	transferase activity, transferring glycosyl groups
IUJ52_07480	COG0438	transferase activity, transferring glycosyl groups
IUJ52_07485	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IUJ52_07500	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IUJ52_07510	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IUJ52_07515	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IUJ52_07520	COG2003	Belongs to the UPF0758 family
IUJ52_07535	COG1309	transcriptional regulator
IUJ52_07540	COG1560	Kdo2-lipid A biosynthetic process
IUJ52_07545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IUJ52_07550	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IUJ52_07555	COG1561	YicC-like family, N-terminal region
IUJ52_07580	COG2862	Uncharacterized protein family, UPF0114
IUJ52_07590	COG4607	ABC-type enterochelin transport system periplasmic component
IUJ52_07595	COG1120	ATPase activity
IUJ52_07600	COG4774	siderophore transport
IUJ52_07605	COG1132	(ABC) transporter
IUJ52_07620	COG0514	ATP-dependent DNA helicase (RecQ)
IUJ52_07625	COG2962	Rard protein
IUJ52_07635	COG1280	lysine exporter protein (LysE YggA)
IUJ52_07640	COG0405	Gamma-glutamyltransferase
IUJ52_07645	COG0210	DNA helicase
IUJ52_07680	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IUJ52_07685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ52_07700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ52_07705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ52_07740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ52_07745	COG0601	transmembrane transport
IUJ52_07750	COG0747	negative chemotaxis
IUJ52_07795	COG1309	transcriptional regulator
IUJ52_07800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ52_07805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ52_07810	COG2960	long-chain fatty acid transporting porin activity
IUJ52_07815	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IUJ52_07820	COG0583	DNA-binding transcription factor activity
IUJ52_07860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IUJ52_07870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IUJ52_07875	COG0408	coproporphyrinogen oxidase activity
IUJ52_07885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IUJ52_07890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IUJ52_07895	COG0551	DNA topoisomerase type I activity
IUJ52_07900	COG2922	Belongs to the Smg family
IUJ52_07905	COG0758	DNA mediated transformation
IUJ52_07915	COG0242	peptide deformylase activity
IUJ52_07925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IUJ52_07925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IUJ52_07930	COG0569	domain protein
IUJ52_07935	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IUJ52_07945	COG1272	protein, Hemolysin III
IUJ52_07950	COG4326	sporulation control protein
IUJ52_07955	COG3084	Protein conserved in bacteria
IUJ52_07965	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IUJ52_07970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ52_07975	COG0204	Acyl-transferase
IUJ52_07980	COG0606	chelatase, subunit chli
IUJ52_07990	COG3978	acetolactate synthase activity
IUJ52_07995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IUJ52_08010	COG0604	alcohol dehydrogenase
IUJ52_08040	COG0425	Belongs to the sulfur carrier protein TusA family
IUJ52_08050	COG2119	membrane
IUJ52_08055	COG0752	glycyl-tRNA synthetase alpha subunit
IUJ52_08060	COG0751	glycine-tRNA ligase activity
IUJ52_08065	COG3977	Valine--pyruvate aminotransferase
IUJ52_08070	COG0071	Belongs to the small heat shock protein (HSP20) family
IUJ52_08080	COG0187	DNA topoisomerase II activity
IUJ52_08090	COG0592	DNA-directed DNA polymerase activity
IUJ52_08095	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IUJ52_08110	COG1126	abc transporter atp-binding protein
IUJ52_08115	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IUJ52_08130	COG0706	membrane insertase activity
IUJ52_08140	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IUJ52_08145	COG0445	tRNA wobble uridine modification
IUJ52_08150	COG0357	Ribosomal RNA small subunit methyltransferase G
IUJ52_08155	COG1192	Involved in chromosome partitioning
IUJ52_08160	COG1475	DNA binding
IUJ52_08165	COG3312	ion transport
IUJ52_08180	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IUJ52_08185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IUJ52_08190	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IUJ52_08195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IUJ52_08200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IUJ52_08205	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IUJ52_08215	COG0765	amino acid transport
IUJ52_08225	COG2814	Major facilitator Superfamily
IUJ52_08230	COG0583	DNA-binding transcription factor activity
IUJ52_08235	COG0183	Belongs to the thiolase family
IUJ52_08245	COG1739	Uncharacterized protein family UPF0029
IUJ52_08250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IUJ52_08325	COG2132	Multicopper oxidase
IUJ52_08330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IUJ52_08335	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
IUJ52_08345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IUJ52_08355	COG2022	thiamine diphosphate biosynthetic process
IUJ52_08360	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IUJ52_08365	COG4175	Glycine betaine
IUJ52_08380	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IUJ52_08385	COG1012	belongs to the aldehyde dehydrogenase family
IUJ52_08390	COG1309	transcriptional regulator
IUJ52_08395	COG0006	proline dipeptidase activity
IUJ52_08395	COG0006	proline dipeptidase activity
IUJ52_08415	COG1522	sequence-specific DNA binding
IUJ52_08420	COG5002	protein histidine kinase activity
IUJ52_08420	COG5001	Diguanylate cyclase
IUJ52_08440	COG0589	response to stress
IUJ52_08445	COG1528	Iron-storage protein
IUJ52_08455	COG2081	HI0933 family
IUJ52_08460	COG1172	Belongs to the binding-protein-dependent transport system permease family
IUJ52_08465	COG1172	Belongs to the binding-protein-dependent transport system permease family
IUJ52_08470	COG1129	ABC transporter
IUJ52_08475	COG1879	ABC-type sugar transport system periplasmic component
IUJ52_08480	COG1172	Belongs to the binding-protein-dependent transport system permease family
IUJ52_08485	COG1129	ABC transporter
IUJ52_08490	COG1879	ABC-type sugar transport system periplasmic component
IUJ52_08495	COG1069	ribulokinase activity
IUJ52_08505	COG2160	L-arabinose isomerase activity
IUJ52_08530	COG1322	Protein conserved in bacteria
IUJ52_08535	COG2226	methyltransferase
IUJ52_08540	COG3165	ubiquinone biosynthetic process from chorismate
IUJ52_08550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IUJ52_08555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IUJ52_08560	COG0805	protein transport
IUJ52_08565	COG0084	hydrolase, TatD family'
IUJ52_08580	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IUJ52_08580	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IUJ52_08610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUJ52_08615	COG3071	HemY protein
IUJ52_08620	COG2959	enzyme of heme biosynthesis
IUJ52_08635	COG3072	Adenylate cyclase
IUJ52_08640	COG1965	Belongs to the frataxin family
IUJ52_08650	COG0019	diaminopimelate decarboxylase activity
IUJ52_08655	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IUJ52_08665	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUJ52_08670	COG1011	Hydrolase
IUJ52_08675	COG2200	EAL domain
IUJ52_08675	COG2199	diguanylate cyclase activity
IUJ52_08675	COG3287	FIST C domain
IUJ52_08680	COG3148	PFAM DTW domain containing protein
IUJ52_08690	COG0561	phosphatase activity
IUJ52_08695	COG2267	carboxylic ester hydrolase activity
IUJ52_08700	COG1280	lysine exporter protein (LysE YggA)
IUJ52_08705	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IUJ52_08710	COG0640	Transcriptional regulator
IUJ52_08715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IUJ52_08730	COG0783	Belongs to the Dps family
IUJ52_08760	COG2095	MarC family integral membrane protein
IUJ52_08770	COG0742	ribosomal rna small subunit methyltransferase
IUJ52_08775	COG0552	protein localization to endoplasmic reticulum
IUJ52_08780	COG2884	Cell division ATP-binding protein ftsE
IUJ52_08785	COG2177	Part of the ABC transporter FtsEX involved in
IUJ52_08790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IUJ52_08795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ52_08800	COG0705	Rhomboid family
IUJ52_08805	COG1580	Controls the rotational direction of flagella during chemotaxis
IUJ52_08810	COG3161	chorismate lyase activity
IUJ52_08815	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IUJ52_08820	COG2937	Belongs to the GPAT DAPAT family
IUJ52_08825	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IUJ52_08830	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IUJ52_08840	COG0534	Mate efflux family protein
IUJ52_08845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ52_08890	COG0328	RNA-DNA hybrid ribonuclease activity
IUJ52_08935	COG2003	Belongs to the UPF0758 family
IUJ52_08950	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IUJ52_08955	COG0732	type I restriction modification DNA specificity domain
IUJ52_08960	COG0514	ATP-dependent DNA helicase (RecQ)
IUJ52_08970	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IUJ52_08975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IUJ52_08990	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IUJ52_09060	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IUJ52_09065	COG3300	MHYT domain
IUJ52_09065	COG5001	Diguanylate cyclase
IUJ52_09070	COG2204	response regulator
IUJ52_09075	COG3852	Histidine kinase
IUJ52_09085	COG0174	glutamine synthetase
IUJ52_09090	COG1217	gtp-binding protein TYPA
IUJ52_09110	COG1490	D-aminoacyl-tRNA deacylase activity
IUJ52_09115	COG0456	acetyltransferase
IUJ52_09120	COG2982	Protein involved in outer membrane biogenesis
IUJ52_09125	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IUJ52_09135	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IUJ52_09140	COG3031	protein transport across the cell outer membrane
IUJ52_09150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUJ52_09155	COG1459	type II secretion system
IUJ52_09160	COG2165	general secretion pathway protein
IUJ52_09165	COG2165	general secretion pathway protein
IUJ52_09170	COG2165	general secretion pathway protein
IUJ52_09175	COG4795	General secretion pathway protein
IUJ52_09180	COG3156	type II secretion system protein K
IUJ52_09185	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IUJ52_09190	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IUJ52_09200	COG1218	3'(2'),5'-bisphosphate nucleotidase
IUJ52_09205	COG0494	nUDIX hydrolase
IUJ52_09215	COG1040	competence protein
IUJ52_09220	COG0596	Alpha beta hydrolase
IUJ52_09230	COG2183	response to ionizing radiation
IUJ52_09240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IUJ52_09245	COG1609	Transcriptional regulator
IUJ52_09250	COG0129	dihydroxy-acid dehydratase activity
IUJ52_09255	COG3265	gluconokinase activity
IUJ52_09260	COG2610	gluconate transmembrane transporter activity
IUJ52_09265	COG0800	Aldolase
IUJ52_09280	COG2233	PERMEase
IUJ52_09285	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IUJ52_09290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IUJ52_09295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUJ52_09300	COG1758	RNA polymerase activity
IUJ52_09305	COG0194	GDP metabolic process
IUJ52_09310	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IUJ52_09315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IUJ52_09340	COG4232	protein-disulfide reductase activity
IUJ52_09350	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IUJ52_09355	COG0540	Belongs to the ATCase OTCase family
IUJ52_09360	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IUJ52_09375	COG1288	antiporter activity
IUJ52_09380	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IUJ52_09385	COG1027	Aspartate ammonia-lyase
IUJ52_09400	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IUJ52_09405	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IUJ52_09410	COG2205	protein histidine kinase activity
IUJ52_09415	COG0745	RESPONSE REGULATOR receiver
IUJ52_09425	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IUJ52_09430	COG0205	6-phosphofructokinase activity
IUJ52_09435	COG1494	fructose-1,6-bisphosphatase
IUJ52_09440	COG3074	FtsZ-dependent cytokinesis
IUJ52_09445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IUJ52_09450	COG0527	aspartate kinase activity
IUJ52_09450	COG0460	homoserine dehydrogenase
IUJ52_09455	COG0626	cystathionine gamma-synthase activity
IUJ52_09460	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
IUJ52_09465	COG0281	malic enzyme
IUJ52_09475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IUJ52_09480	COG1609	Transcriptional regulator
IUJ52_09490	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IUJ52_09495	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IUJ52_09500	COG1575	Belongs to the MenA family. Type 1 subfamily
IUJ52_09505	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ52_09510	COG0534	Mate efflux family protein
IUJ52_09515	COG0149	triose-phosphate isomerase activity
IUJ52_09545	COG0459	protein refolding
IUJ52_09550	COG1119	ATPase activity
IUJ52_09560	COG1285	pathogenesis
IUJ52_09565	COG1509	lysine 2,3-aminomutase activity
IUJ52_09570	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IUJ52_09580	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IUJ52_09585	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IUJ52_09590	COG1053	succinate dehydrogenase
IUJ52_09595	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IUJ52_09600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ52_09605	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IUJ52_09615	COG1045	serine acetyltransferase
IUJ52_09625	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IUJ52_09630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IUJ52_09635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IUJ52_09640	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IUJ52_09645	COG0137	argininosuccinate synthase activity
IUJ52_09650	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IUJ52_09650	COG0165	Argininosuccinate lyase
IUJ52_09660	COG0678	peroxiredoxin activity
IUJ52_09660	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IUJ52_09670	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IUJ52_09705	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IUJ52_09715	COG0338	D12 class N6 adenine-specific DNA methyltransferase
IUJ52_09720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IUJ52_09730	COG0180	Tryptophanyl-tRNA synthetase
IUJ52_09740	COG0512	Glutamine amidotransferase of anthranilate synthase
IUJ52_09745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IUJ52_09755	COG1012	belongs to the aldehyde dehydrogenase family
IUJ52_09770	COG3954	Phosphoribulokinase
IUJ52_09780	COG0429	hydrolase of the alpha beta-hydrolase fold
IUJ52_09790	COG0488	(ABC) transporter
IUJ52_09795	COG2249	NAD(P)H dehydrogenase (quinone) activity
IUJ52_09805	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IUJ52_09810	COG1047	Peptidyl-prolyl cis-trans
IUJ52_09820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IUJ52_09825	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
IUJ52_09830	COG3083	sulfuric ester hydrolase activity
IUJ52_09835	COG0557	exoribonuclease II activity
IUJ52_09840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IUJ52_09845	COG0051	transcription antitermination factor activity, RNA binding
IUJ52_09850	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IUJ52_09855	COG0088	Forms part of the polypeptide exit tunnel
IUJ52_09860	COG0089	rRNA binding
IUJ52_09865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IUJ52_09870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IUJ52_09875	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IUJ52_09880	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IUJ52_09885	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IUJ52_09890	COG0255	Belongs to the universal ribosomal protein uL29 family
IUJ52_09895	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IUJ52_09900	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IUJ52_09905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IUJ52_09910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IUJ52_09915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IUJ52_09920	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IUJ52_09930	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IUJ52_09940	COG1841	ribosomal large subunit assembly
IUJ52_09945	COG0200	Binds to the 23S rRNA
IUJ52_09950	COG0201	protein transport
IUJ52_09955	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IUJ52_09960	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IUJ52_09965	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IUJ52_09970	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IUJ52_09975	COG0202	RNA polymerase activity
IUJ52_09980	COG0203	ribosomal protein L17
IUJ52_09990	COG0545	Peptidyl-prolyl cis-trans isomerase
IUJ52_09995	COG3061	Opacity-associated protein A
IUJ52_10005	COG2153	protein acetylation
IUJ52_10010	COG0513	Belongs to the DEAD box helicase family
IUJ52_10020	COG0737	Belongs to the 5'-nucleotidase family
IUJ52_10025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IUJ52_10025	COG1648	precorrin-2 dehydrogenase activity
IUJ52_10030	COG0175	sulfate reduction
IUJ52_10035	COG2895	sulfate adenylyltransferase (ATP) activity
IUJ52_10040	COG3273	potassium ion transport
IUJ52_10040	COG0471	metal ion transport
IUJ52_10045	COG0529	Catalyzes the synthesis of activated sulfate
IUJ52_10065	COG1136	(ABC) transporter
IUJ52_10065	COG0577	efflux transmembrane transporter activity
IUJ52_10080	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IUJ52_10085	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ52_10090	COG0729	surface antigen
IUJ52_10100	COG2105	PFAM AIG2 family protein
IUJ52_10110	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IUJ52_10115	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IUJ52_10120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUJ52_10125	COG0163	prenyltransferase activity
IUJ52_10135	COG1178	ABC-type Fe3 transport system permease component
IUJ52_10140	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IUJ52_10145	COG3028	Belongs to the UPF0307 family
IUJ52_10150	COG0312	modulator of DNA gyrase
IUJ52_10155	COG2239	Acts as a magnesium transporter
IUJ52_10160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ52_10165	COG1660	Displays ATPase and GTPase activities
IUJ52_10170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ52_10175	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IUJ52_10185	COG1137	ATPase activity
IUJ52_10190	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IUJ52_10200	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IUJ52_10205	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IUJ52_10205	COG0517	IMP dehydrogenase activity
IUJ52_10215	COG1127	ABC transporter
IUJ52_10220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUJ52_10225	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IUJ52_10230	COG2854	intermembrane phospholipid transfer
IUJ52_10235	COG3113	response to antibiotic
IUJ52_10240	COG5007	Belongs to the BolA IbaG family
IUJ52_10250	COG0204	Acyl-transferase
IUJ52_10255	COG0251	oxidation-reduction process
IUJ52_10260	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IUJ52_10265	COG0540	Belongs to the ATCase OTCase family
IUJ52_10270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IUJ52_10275	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IUJ52_10290	COG0564	pseudouridine synthase activity
IUJ52_10295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ52_10300	COG0525	valine-tRNA ligase activity
IUJ52_10310	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IUJ52_10315	COG0795	lipopolysaccharide-transporting ATPase activity
IUJ52_10320	COG0795	lipopolysaccharide-transporting ATPase activity
IUJ52_10330	COG3706	GGDEF domain
IUJ52_10355	COG3437	response regulator, receiver
IUJ52_10400	COG0066	3-isopropylmalate dehydratase activity
IUJ52_10405	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
IUJ52_10410	COG0473	3-isopropylmalate dehydrogenase activity
IUJ52_10435	COG0583	DNA-binding transcription factor activity
IUJ52_10440	COG1022	Amp-dependent synthetase and ligase
IUJ52_10445	COG0028	Belongs to the TPP enzyme family
IUJ52_10450	COG0440	acetolactate synthase activity
IUJ52_10455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ52_10460	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IUJ52_10465	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IUJ52_10475	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IUJ52_10480	COG3079	Belongs to the UPF0149 family
IUJ52_10485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ52_10490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ52_10510	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IUJ52_10520	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
IUJ52_10525	COG1595	DNA-templated transcription, initiation
IUJ52_10540	COG3086	response to oxidative stress
IUJ52_10545	COG0481	GTPase activity
IUJ52_10560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IUJ52_10565	COG1381	Involved in DNA repair and RecF pathway recombination
IUJ52_10570	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IUJ52_10585	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IUJ52_10590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUJ52_10595	COG3956	TIGRFAM MazG family protein
IUJ52_10600	COG0504	CTP synthase activity
IUJ52_10605	COG0148	phosphopyruvate hydratase activity
IUJ52_10610	COG0617	tRNA 3'-terminal CCA addition
IUJ52_10615	COG3267	Type II secretory pathway component ExeA
IUJ52_10615	COG3409	Peptidoglycan-binding domain 1 protein
IUJ52_10625	COG4991	sh3 domain protein
IUJ52_10630	COG0306	phosphate transporter
IUJ52_10635	COG1392	Phosphate transport regulator
IUJ52_10640	COG3025	triphosphatase activity
IUJ52_10645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUJ52_10655	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IUJ52_10660	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IUJ52_10660	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IUJ52_10665	COG1538	Outer membrane efflux protein
IUJ52_10670	COG0494	nUDIX hydrolase
IUJ52_10675	COG3151	Protein conserved in bacteria
IUJ52_10685	COG3150	esterase
IUJ52_10705	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IUJ52_10710	COG0237	dephospho-CoA kinase activity
IUJ52_10720	COG1459	type II secretion system
IUJ52_10725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUJ52_10750	COG4974	Belongs to the 'phage' integrase family
IUJ52_10755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ52_10760	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IUJ52_10765	COG2186	Transcriptional regulator
IUJ52_10770	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IUJ52_10775	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ52_10780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ52_10795	COG0288	reversible hydration of carbon dioxide
IUJ52_10800	COG1131	(ABC) transporter
IUJ52_10805	COG0842	Transport permease protein
IUJ52_10810	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IUJ52_10815	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IUJ52_10820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IUJ52_10830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ52_10835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IUJ52_10840	COG1489	DNA binding
IUJ52_10845	COG1643	Atp-dependent helicase
IUJ52_10850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IUJ52_10855	COG1752	Esterase of the alpha-beta hydrolase superfamily
IUJ52_10860	COG1049	propionate catabolic process, 2-methylcitrate cycle
IUJ52_10865	COG3112	Uncharacterised protein family (UPF0231)
IUJ52_10870	COG0347	Belongs to the P(II) protein family
IUJ52_10875	COG0004	ammonium transporteR
IUJ52_10880	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ52_10890	COG3842	ATPase activity
IUJ52_10895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUJ52_10910	COG2971	BadF BadG BcrA BcrD
IUJ52_10920	COG4608	Belongs to the ABC transporter superfamily
IUJ52_10925	COG0444	Belongs to the ABC transporter superfamily
IUJ52_10930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ52_10940	COG0747	negative chemotaxis
IUJ52_10945	COG0784	Response regulator, receiver
IUJ52_10945	COG2205	protein histidine kinase activity
IUJ52_10950	COG2813	Specifically methylates the guanine in position
IUJ52_10955	COG0628	permease
IUJ52_10960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IUJ52_10965	COG0316	Belongs to the HesB IscA family
IUJ52_10980	COG0739	heme binding
IUJ52_10985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IUJ52_10995	COG2239	Acts as a magnesium transporter
IUJ52_11000	COG2027	D-alanyl-D-alanine carboxypeptidase
IUJ52_11005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IUJ52_11010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IUJ52_11015	COG1534	Rna-binding protein
IUJ52_11020	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IUJ52_11025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IUJ52_11030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IUJ52_11035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUJ52_11040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IUJ52_11055	COG0779	Required for maturation of 30S ribosomal subunits
IUJ52_11060	COG0195	Participates in both transcription termination and antitermination
IUJ52_11065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IUJ52_11070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IUJ52_11080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IUJ52_11100	COG0534	Mate efflux family protein
IUJ52_11105	COG0826	peptidase U32
IUJ52_11110	COG0826	peptidase U32
IUJ52_11120	COG3154	lipid carrier protein
IUJ52_11125	COG3153	acetyltransferase
IUJ52_11150	COG0513	Belongs to the DEAD box helicase family
IUJ52_11155	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IUJ52_11170	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IUJ52_11175	COG2204	response regulator
IUJ52_11185	COG0667	Aldo Keto reductase
IUJ52_11200	COG0494	nUDIX hydrolase
IUJ52_11210	COG0730	response to heat
IUJ52_11220	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IUJ52_11225	COG1283	sodium-dependent phosphate transmembrane transporter activity
IUJ52_11230	COG0583	DNA-binding transcription factor activity
IUJ52_11235	COG0640	Transcriptional regulator
IUJ52_11240	COG0268	Binds directly to 16S ribosomal RNA
IUJ52_11245	COG0728	peptidoglycan biosynthetic process
IUJ52_11250	COG0196	riboflavin kinase activity
IUJ52_11255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IUJ52_11260	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IUJ52_11265	COG1047	Peptidyl-prolyl cis-trans
IUJ52_11270	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IUJ52_11275	COG1966	Carbon starvation protein
IUJ52_11290	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IUJ52_11295	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IUJ52_11305	COG3279	Response regulator of the LytR AlgR family
IUJ52_11310	COG3275	phosphorelay sensor kinase activity
IUJ52_11315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ52_11320	COG0287	Prephenate dehydrogenase
IUJ52_11320	COG1605	Chorismate mutase
IUJ52_11330	COG0488	(ABC) transporter
IUJ52_11340	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
IUJ52_11345	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
IUJ52_11350	COG5001	Diguanylate cyclase
IUJ52_11355	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IUJ52_11360	COG0077	Prephenate dehydratase
IUJ52_11360	COG1605	Chorismate mutase
IUJ52_11365	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IUJ52_11370	COG0741	lytic transglycosylase activity
IUJ52_11375	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ52_11380	COG0564	pseudouridine synthase activity
IUJ52_11390	COG0542	response to heat
IUJ52_11400	COG0590	tRNA wobble adenosine to inosine editing
IUJ52_11405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ52_11415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ52_11475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IUJ52_11490	COG0271	Belongs to the BolA IbaG family
IUJ52_11495	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IUJ52_11500	COG1805	sodium ion transport
IUJ52_11510	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IUJ52_11515	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IUJ52_11520	COG2871	sodium ion transport
IUJ52_11525	COG1477	protein flavinylation
IUJ52_11540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IUJ52_11550	COG5001	Diguanylate cyclase
IUJ52_11550	COG2203	Gaf domain
IUJ52_11550	COG3706	GGDEF domain
IUJ52_11550	COG4251	negative regulation of phosphorylation
IUJ52_11555	COG0733	neurotransmitter:sodium symporter activity
IUJ52_11565	COG0189	ligase activity
IUJ52_11570	COG0189	ligase activity
IUJ52_11570	COG4067	protein conserved in archaea
IUJ52_11575	COG2195	Cleaves the N-terminal amino acid of tripeptides
IUJ52_11580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ52_11585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ52_11595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ52_11605	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ52_11610	COG2252	PERMEase
IUJ52_11615	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
IUJ52_11620	COG1073	alpha beta
IUJ52_11635	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IUJ52_11640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IUJ52_11645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUJ52_11645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUJ52_11660	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IUJ52_11665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IUJ52_11670	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IUJ52_11675	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IUJ52_11685	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
IUJ52_11690	COG0024	Methionine aminopeptidase
IUJ52_11695	COG0052	Belongs to the universal ribosomal protein uS2 family
IUJ52_11700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IUJ52_11710	COG0233	cytoplasmic translational termination
IUJ52_11715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IUJ52_11720	COG0575	Belongs to the CDS family
IUJ52_11725	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IUJ52_11730	COG0750	zinc metalloprotease
IUJ52_11740	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IUJ52_11745	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ52_11750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IUJ52_11765	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IUJ52_11770	COG0587	DNA-directed DNA polymerase activity
IUJ52_11775	COG0825	malonyl-CoA metabolic process
IUJ52_11780	COG0037	tRNA processing
IUJ52_11790	COG0347	Belongs to the P(II) protein family
IUJ52_11795	COG3021	interspecies interaction between organisms
IUJ52_11805	COG1388	LysM domain
IUJ52_11805	COG0741	lytic transglycosylase activity
IUJ52_11810	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ52_11815	COG2226	methyltransferase
IUJ52_11820	COG0328	RNA-DNA hybrid ribonuclease activity
IUJ52_11825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IUJ52_11835	COG1960	acyl-CoA dehydrogenase activity
IUJ52_11840	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IUJ52_11845	COG0121	glutamine amidotransferase
IUJ52_11850	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IUJ52_11855	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IUJ52_11860	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IUJ52_11865	COG1187	pseudouridine synthase activity
IUJ52_11870	COG2840	Smr protein MutS2
IUJ52_11900	COG2217	Heavy metal translocating P-type atpase
IUJ52_11900	COG2608	mercury ion transmembrane transporter activity
IUJ52_11905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ52_11945	COG2747	anti-sigma28 factor FlgM
IUJ52_11955	COG0835	chemotaxis
IUJ52_11955	COG0784	Response regulator, receiver
IUJ52_11960	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IUJ52_11965	COG1815	bacterial-type flagellum-dependent cell motility
IUJ52_11985	COG4787	bacterial-type flagellum-dependent cell motility
IUJ52_11995	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IUJ52_12000	COG1706	bacterial-type flagellum-dependent cell motility
IUJ52_12005	COG1705	Flagellar rod assembly protein muramidase FlgJ
IUJ52_12005	COG3951	Flagellar rod assembly protein muramidase FlgJ
IUJ52_12015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IUJ52_12020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IUJ52_12125	COG0193	aminoacyl-tRNA hydrolase activity
IUJ52_12130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IUJ52_12135	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IUJ52_12140	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IUJ52_12145	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
IUJ52_12150	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IUJ52_12155	COG2890	protein-(glutamine-N5) methyltransferase activity
IUJ52_12165	COG2912	Transglutaminase-like superfamily
IUJ52_12170	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IUJ52_12175	COG0737	Belongs to the 5'-nucleotidase family
IUJ52_12180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IUJ52_12185	COG2233	PERMEase
IUJ52_12205	COG1393	Belongs to the ArsC family
IUJ52_12210	COG4783	chaperone-mediated protein folding
IUJ52_12230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IUJ52_12235	COG2716	regulation of RNA biosynthetic process
IUJ52_12245	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IUJ52_12255	COG1876	peptidase activity
IUJ52_12265	COG1393	Belongs to the ArsC family
IUJ52_12275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IUJ52_12280	COG1085	galactose-1-phosphate uridylyltransferase
IUJ52_12285	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IUJ52_12300	COG0517	IMP dehydrogenase activity
IUJ52_12320	COG2837	iron assimilation
IUJ52_12335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IUJ52_12340	COG1334	flagellar protein FlaG
IUJ52_12345	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IUJ52_12355	COG1516	flagellar protein fliS
IUJ52_12375	COG1677	Flagellar hook-basal body complex protein FliE
IUJ52_12385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
IUJ52_12435	COG1987	bacterial-type flagellum assembly
IUJ52_12450	COG2840	Smr protein MutS2
IUJ52_12455	COG2890	protein-(glutamine-N5) methyltransferase activity
IUJ52_12460	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IUJ52_12465	COG2860	membrane
IUJ52_12470	COG3101	peptidyl-lysine hydroxylation
IUJ52_12485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IUJ52_12485	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IUJ52_12490	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUJ52_12495	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ52_12500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IUJ52_12505	COG0735	belongs to the Fur family
IUJ52_12515	COG0583	DNA-binding transcription factor activity
IUJ52_12520	COG1380	Effector of murein hydrolase LrgA
IUJ52_12525	COG1346	cytolysis
IUJ52_12540	COG0596	Alpha beta hydrolase
IUJ52_12545	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
IUJ52_12550	COG0033	Phosphoglucomutase
IUJ52_12560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IUJ52_12575	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IUJ52_12580	COG1053	succinate dehydrogenase
IUJ52_12590	COG0567	Dehydrogenase, E1 component
IUJ52_12595	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ52_12610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IUJ52_12615	COG1121	(ABC) transporter
IUJ52_12620	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IUJ52_12625	COG2207	Transcriptional regulator
IUJ52_12630	COG1918	ferrous iron import across plasma membrane
IUJ52_12650	COG0018	arginyl-trna synthetase
IUJ52_12655	COG3102	Protein conserved in bacteria
IUJ52_12665	COG2062	phosphohistidine phosphatase, SixA
IUJ52_12695	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
IUJ52_12700	COG0784	Response regulator, receiver
IUJ52_12700	COG2198	Histidine kinase
IUJ52_12700	COG0643	Histidine kinase
IUJ52_12705	COG2201	protein-glutamate methylesterase activity
IUJ52_12710	COG1192	Involved in chromosome partitioning
IUJ52_12720	COG0835	chemotaxis
IUJ52_12730	COG4133	protoheme IX ABC transporter activity
IUJ52_12735	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IUJ52_12740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IUJ52_12745	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IUJ52_12750	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IUJ52_12755	COG1138	Cytochrome C-type biogenesis protein
IUJ52_12760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ52_12775	COG2853	Lipoprotein
IUJ52_12805	COG1609	Transcriptional regulator
IUJ52_12815	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IUJ52_12820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IUJ52_12825	COG3384	dioxygenase
IUJ52_12845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ52_12850	COG0667	Aldo Keto reductase
IUJ52_12865	COG0583	DNA-binding transcription factor activity
IUJ52_12870	COG2159	amidohydrolase
IUJ52_12875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ52_12915	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IUJ52_12930	COG0123	including yeast histone deacetylase and acetoin utilization protein
IUJ52_12940	COG1448	Aminotransferase
IUJ52_12960	COG2814	Major facilitator Superfamily
IUJ52_12975	COG3083	sulfuric ester hydrolase activity
IUJ52_12980	COG3082	Protein of unknown function (DUF1414)
IUJ52_12985	COG3081	Nucleoid-associated protein
IUJ52_12995	COG1757	Na H antiporter
IUJ52_13000	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IUJ52_13005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUJ52_13010	COG2095	MarC family integral membrane protein
IUJ52_13015	COG1012	belongs to the aldehyde dehydrogenase family
IUJ52_13015	COG1454	alcohol dehydrogenase
IUJ52_13025	COG0659	secondary active sulfate transmembrane transporter activity
IUJ52_13035	COG1530	ribonuclease E activity
IUJ52_13040	COG0564	pseudouridine synthase activity
IUJ52_13045	COG0424	maF-like protein
IUJ52_13050	COG1399	metal-binding, possibly nucleic acid-binding protein
IUJ52_13055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IUJ52_13060	COG0416	fatty acid biosynthetic process
IUJ52_13065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUJ52_13085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUJ52_13090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IUJ52_13095	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IUJ52_13100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IUJ52_13105	COG0470	DNA polymerase III
IUJ52_13110	COG0084	hydrolase, TatD family'
IUJ52_13115	COG2190	(PTS) system
IUJ52_13115	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ52_13115	COG1263	PTS System
IUJ52_13125	COG1263	PTS System
IUJ52_13125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ52_13140	COG0733	neurotransmitter:sodium symporter activity
IUJ52_13155	COG4667	esterase of the alpha-beta hydrolase superfamily
IUJ52_13160	COG0469	pyruvate kinase activity
IUJ52_13165	COG1940	carbohydrate kinase activity
IUJ52_13170	COG0784	Response regulator, receiver
IUJ52_13170	COG0835	chemotaxis
IUJ52_13175	COG0587	DNA-directed DNA polymerase activity
IUJ52_13190	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_13195	COG0616	signal peptide processing
IUJ52_13215	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IUJ52_13220	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
IUJ52_13225	COG0436	Aminotransferase
IUJ52_13235	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
IUJ52_13245	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IUJ52_13265	COG2855	membrane
IUJ52_13270	COG0477	Major facilitator Superfamily
IUJ52_13290	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IUJ52_13295	COG0741	lytic transglycosylase activity
IUJ52_13295	COG1388	LysM domain
IUJ52_13315	COG1815	bacterial-type flagellum-dependent cell motility
IUJ52_13320	COG1558	bacterial-type flagellum-dependent cell motility
IUJ52_13325	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
IUJ52_13330	COG1749	Flagellar hook protein flgE
IUJ52_13340	COG4786	Flagellar basal body rod
IUJ52_13345	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
IUJ52_13350	COG1706	bacterial-type flagellum-dependent cell motility
IUJ52_13360	COG1256	bacterial-type flagellum assembly
IUJ52_13360	COG4786	Flagellar basal body rod
IUJ52_13385	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
IUJ52_13410	COG1403	HNH endonuclease
IUJ52_13430	COG3015	lipoprotein NlpE involved in copper resistance
IUJ52_13440	COG1360	Flagellar Motor Protein
IUJ52_13445	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
IUJ52_13450	COG1191	sigma factor activity
IUJ52_13455	COG1580	Controls the rotational direction of flagella during chemotaxis
IUJ52_13475	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IUJ52_13480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IUJ52_13495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IUJ52_13525	COG2885	chlorophyll binding
IUJ52_13525	COG3047	cAMP biosynthetic process
IUJ52_13570	COG1522	sequence-specific DNA binding
IUJ52_13575	COG1946	Acyl-CoA thioesterase
IUJ52_13580	COG3126	Type III secretion system lipoprotein chaperone (YscW)
IUJ52_13595	COG5001	Diguanylate cyclase
IUJ52_13595	COG5002	protein histidine kinase activity
IUJ52_13615	COG0679	Auxin Efflux Carrier
IUJ52_13620	COG3711	transcriptional antiterminator
IUJ52_13625	COG1263	PTS System
IUJ52_13625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ52_13625	COG2190	(PTS) system
IUJ52_13630	COG2723	6-phospho-beta-galactosidase activity
IUJ52_13650	COG1881	PFAM PEBP family protein
IUJ52_13655	COG2207	Transcriptional regulator
IUJ52_13690	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ52_13695	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ52_13715	COG0513	Belongs to the DEAD box helicase family
IUJ52_13720	COG1368	sulfuric ester hydrolase activity
IUJ52_13725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IUJ52_13730	COG2194	sulfuric ester hydrolase activity
IUJ52_13770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ52_13775	COG1271	oxidase subunit
IUJ52_13780	COG1294	oxidase, subunit
IUJ52_13805	COG2223	nitrite transmembrane transporter activity
IUJ52_13810	COG3279	Response regulator of the LytR AlgR family
IUJ52_13815	COG3275	phosphorelay sensor kinase activity
IUJ52_13830	COG2249	NAD(P)H dehydrogenase (quinone) activity
IUJ52_13845	COG1021	2,3-dihydroxybenzoate-AMP ligase
IUJ52_13850	COG1169	isochorismate synthase
IUJ52_13855	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_13860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ52_13865	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ52_13865	COG3433	isochorismatase activity
IUJ52_13865	COG2226	methyltransferase
IUJ52_13880	COG4592	Periplasmic binding protein
IUJ52_13885	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ52_13890	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ52_13895	COG1629	transport
IUJ52_13895	COG4774	siderophore transport
IUJ52_13905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ52_13910	COG1120	ATPase activity
IUJ52_13920	COG1609	Transcriptional regulator
IUJ52_13925	COG2723	6-phospho-beta-galactosidase activity
IUJ52_13930	COG1741	Belongs to the pirin family
IUJ52_13940	COG4172	Belongs to the ABC transporter superfamily
IUJ52_13945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ52_13950	COG0601	transmembrane transport
IUJ52_13955	COG0747	negative chemotaxis
IUJ52_13965	COG1538	Outer membrane efflux protein
IUJ52_13970	COG1566	PFAM secretion protein HlyD family protein
IUJ52_13975	COG2814	Major facilitator Superfamily
IUJ52_13980	COG2207	Transcriptional regulator
IUJ52_13980	COG3708	Transcriptional regulator
IUJ52_13990	COG0745	RESPONSE REGULATOR receiver
IUJ52_14000	COG1263	PTS System
IUJ52_14000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IUJ52_14015	COG3706	GGDEF domain
IUJ52_14015	COG2203	Gaf domain
IUJ52_14015	COG4251	negative regulation of phosphorylation
IUJ52_14015	COG5001	Diguanylate cyclase
IUJ52_14025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ52_14045	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_14055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IUJ52_14080	COG2986	histidine ammonia-lyase
IUJ52_14085	COG1216	Glycosyl transferase, family 2
IUJ52_14105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ52_14110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ52_14115	COG0204	Acyl-transferase
IUJ52_14115	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ52_14145	COG0601	transmembrane transport
IUJ52_14150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ52_14155	COG0444	Belongs to the ABC transporter superfamily
IUJ52_14170	COG0435	Glutathione S-transferase
IUJ52_14175	COG3174	membrane
IUJ52_14180	COG0857	belongs to the CobB CobQ family
IUJ52_14180	COG0280	phosphate acetyltransferase
IUJ52_14185	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IUJ52_14190	COG3092	negative regulation of chromosome organization
IUJ52_14200	COG4120	Belongs to the binding-protein-dependent transport system permease family
IUJ52_14210	COG3706	GGDEF domain
IUJ52_14220	COG2165	general secretion pathway protein
IUJ52_14225	COG0653	protein targeting
IUJ52_14230	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IUJ52_14235	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IUJ52_14240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IUJ52_14250	COG0243	molybdopterin cofactor binding
IUJ52_14255	COG1648	precorrin-2 dehydrogenase activity
IUJ52_14255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IUJ52_14270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ52_14270	COG1116	anion transmembrane transporter activity
IUJ52_14275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ52_14280	COG1116	anion transmembrane transporter activity
IUJ52_14285	COG2146	nitrite reductase [NAD(P)H] activity
IUJ52_14285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ52_14295	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IUJ52_14300	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
IUJ52_14305	COG0156	8-amino-7-oxononanoate synthase activity
IUJ52_14310	COG2226	methyltransferase
IUJ52_14315	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
IUJ52_14325	COG0501	Belongs to the peptidase M48B family
IUJ52_14335	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_14350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ52_14370	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IUJ52_14375	COG2915	High frequency lysogenization protein hflD homolog
IUJ52_14380	COG0482	sulfurtransferase activity
IUJ52_14385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ52_14390	COG2916	Histone family protein nucleoid-structuring protein H-NS
IUJ52_14395	COG1757	Na H antiporter
IUJ52_14405	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IUJ52_14410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IUJ52_14415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IUJ52_14420	COG0131	Imidazoleglycerol-phosphate dehydratase
IUJ52_14420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IUJ52_14425	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IUJ52_14430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IUJ52_14440	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IUJ52_14440	COG0140	phosphoribosyl-ATP diphosphatase activity
IUJ52_14445	COG1187	pseudouridine synthase activity
IUJ52_14455	COG1695	Transcriptional regulator
IUJ52_14460	COG2223	nitrite transmembrane transporter activity
IUJ52_14470	COG1278	Cold shock
IUJ52_14475	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IUJ52_14480	COG0542	response to heat
IUJ52_14485	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IUJ52_14490	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
IUJ52_14495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IUJ52_14515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IUJ52_14525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IUJ52_14530	COG0297	glycogen (starch) synthase activity
IUJ52_14550	COG3070	regulator of competence-specific genes
IUJ52_14555	COG1609	Transcriptional regulator
IUJ52_14560	COG3381	protein complex oligomerization
IUJ52_14565	COG0745	RESPONSE REGULATOR receiver
IUJ52_14570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IUJ52_14575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IUJ52_14580	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
IUJ52_14585	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IUJ52_14610	COG0189	ligase activity
IUJ52_14610	COG4067	protein conserved in archaea
IUJ52_14615	COG0500	methyltransferase
IUJ52_14620	COG4106	trans-aconitate 2-methyltransferase activity
IUJ52_14625	COG1801	Protein of unknown function DUF72
IUJ52_14635	COG1435	thymidine kinase activity
IUJ52_14640	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IUJ52_14645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ52_14650	COG0583	DNA-binding transcription factor activity
IUJ52_14665	COG2116	formate transmembrane transporter activity
IUJ52_14670	COG0390	transport system, permease component
IUJ52_14675	COG4459	periplasmic nitrate reductase
IUJ52_14680	COG3005	denitrification pathway
IUJ52_14685	COG0243	molybdopterin cofactor binding
IUJ52_14705	COG1227	inorganic diphosphatase activity
IUJ52_14720	COG4172	Belongs to the ABC transporter superfamily
IUJ52_14730	COG4171	peptide transport system, permease
IUJ52_14735	COG4168	peptide transport system, permease
IUJ52_14745	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
IUJ52_14750	COG1842	Phage shock protein A
IUJ52_14765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ52_14780	COG2818	Glycosylase
IUJ52_14785	COG0626	cystathionine gamma-synthase activity
IUJ52_14795	COG0733	neurotransmitter:sodium symporter activity
IUJ52_14805	COG0564	pseudouridine synthase activity
IUJ52_14815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ52_14820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IUJ52_14825	COG4136	ATPase activity
IUJ52_14830	COG4135	transport system, permease component
IUJ52_14835	COG4134	Bacterial extracellular solute-binding protein
IUJ52_14845	COG3313	Fe-S protein
IUJ52_14855	COG0842	Transport permease protein
IUJ52_14860	COG1131	(ABC) transporter
IUJ52_14870	COG0814	amino acid
IUJ52_14880	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IUJ52_14890	COG1278	Cold shock
IUJ52_14925	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IUJ52_14930	COG0642	Histidine kinase
IUJ52_14945	COG1061	Type III restriction enzyme res subunit
IUJ52_14955	COG2814	Major facilitator Superfamily
IUJ52_14965	COG0702	epimerase
IUJ52_14970	COG0534	Mate efflux family protein
IUJ52_14975	COG4181	ATPase activity
IUJ52_14990	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IUJ52_15035	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IUJ52_15050	COG3265	gluconokinase activity
IUJ52_15055	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IUJ52_15085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IUJ52_15090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IUJ52_15105	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IUJ52_15130	COG2989	Protein conserved in bacteria
IUJ52_15135	COG3108	Peptidase M15
IUJ52_15140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ52_15155	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IUJ52_15180	COG1846	Transcriptional regulator
IUJ52_15185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IUJ52_15190	COG0840	transmembrane signaling receptor activity
IUJ52_15195	COG2176	DNA-directed DNA polymerase activity
IUJ52_15210	COG1448	Aminotransferase
IUJ52_15225	COG0017	Asparaginyl-tRNA synthetase
IUJ52_15235	COG0720	synthase
IUJ52_15255	COG0577	efflux transmembrane transporter activity
IUJ52_15255	COG1136	(ABC) transporter
IUJ52_15260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ52_15265	COG1760	l-serine dehydratase
IUJ52_15270	COG0814	amino acid
IUJ52_15310	COG0714	Associated with various cellular activities
IUJ52_15390	COG1288	antiporter activity
IUJ52_15395	COG2988	succinylglutamate desuccinylase activity
IUJ52_15415	COG1192	Involved in chromosome partitioning
IUJ52_15430	COG3609	addiction module antidote protein, CC2985 family
IUJ52_15475	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ52_15485	COG1902	pentaerythritol trinitrate reductase activity
IUJ52_15490	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IUJ52_15495	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_15545	COG5001	Diguanylate cyclase
IUJ52_15545	COG3706	GGDEF domain
IUJ52_15545	COG2203	Gaf domain
IUJ52_15545	COG4251	negative regulation of phosphorylation
IUJ52_15565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IUJ52_15595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IUJ52_15600	COG0668	transmembrane transport
IUJ52_15670	COG1349	DNA-binding transcription factor activity
IUJ52_15685	COG0583	DNA-binding transcription factor activity
IUJ52_15690	COG2910	NAD(P)H-binding
IUJ52_15705	COG1335	isochorismatase
IUJ52_15710	COG1609	Transcriptional regulator
IUJ52_15710	COG2207	Transcriptional regulator
IUJ52_15725	COG2329	Antibiotic biosynthesis monooxygenase
IUJ52_15730	COG3304	Inner membrane component domain
IUJ52_15740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ52_15745	COG2199	diguanylate cyclase activity
IUJ52_15760	COG0583	DNA-binding transcription factor activity
IUJ52_15765	COG4221	oxidoreductase activity
IUJ52_15785	COG0583	DNA-binding transcription factor activity
IUJ52_15790	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IUJ52_15795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ52_15800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ52_15805	COG2814	Major facilitator Superfamily
IUJ52_15815	COG3118	belongs to the thioredoxin family
IUJ52_15820	COG3118	belongs to the thioredoxin family
IUJ52_15825	COG0492	ferredoxin-NADP+ reductase activity
IUJ52_15830	COG1309	transcriptional regulator
IUJ52_15840	COG2176	DNA-directed DNA polymerase activity
IUJ52_15855	COG0443	Heat shock 70 kDa protein
IUJ52_15860	COG0095	Lipoate-protein ligase
IUJ52_15865	COG0243	molybdopterin cofactor binding
IUJ52_15870	COG0437	4 iron, 4 sulfur cluster binding
IUJ52_15875	COG3302	dmso reductase anchor subunit
IUJ52_15885	COG2221	Nitrite and sulphite reductase 4Fe-4S
IUJ52_15885	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ52_15895	COG0583	DNA-binding transcription factor activity
IUJ52_15900	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IUJ52_15905	COG1473	amidohydrolase
IUJ52_15920	COG2376	Dihydroxyacetone kinase
IUJ52_15925	COG1461	Dihydroxyacetone kinase
IUJ52_15930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IUJ52_15935	COG3284	Transcriptional regulator
IUJ52_15945	COG3722	fumarate hydratase activity
IUJ52_15950	COG0246	Mannitol dehydrogenase
IUJ52_15955	COG2213	PTS system mannitol-specific
IUJ52_15955	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ52_15960	COG0739	heme binding
IUJ52_15975	COG0363	glucosamine-6-phosphate deaminase activity
IUJ52_16000	COG0402	S-adenosylhomocysteine deaminase activity
IUJ52_16005	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IUJ52_16010	COG2259	Doxx family
IUJ52_16015	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IUJ52_16020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUJ52_16030	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
IUJ52_16035	COG1301	dicarboxylic acid transport
IUJ52_16045	COG1917	Cupin 2, conserved barrel domain protein
IUJ52_16045	COG2169	Transcriptional regulator
IUJ52_16075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ52_16085	COG0583	DNA-binding transcription factor activity
IUJ52_16090	COG1342	Belongs to the UPF0251 family
IUJ52_16100	COG0583	DNA-binding transcription factor activity
IUJ52_16105	COG3384	dioxygenase
IUJ52_16120	COG4774	siderophore transport
IUJ52_16125	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IUJ52_16130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ52_16135	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ52_16140	COG1120	ATPase activity
IUJ52_16150	COG0583	DNA-binding transcription factor activity
IUJ52_16155	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_16170	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ52_16185	COG2084	Dehydrogenase
IUJ52_16205	COG3152	Membrane
IUJ52_16225	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ52_16240	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IUJ52_16255	COG1620	l-lactate permease
IUJ52_16260	COG0583	DNA-binding transcription factor activity
IUJ52_16265	COG4172	Belongs to the ABC transporter superfamily
IUJ52_16275	COG1067	ATP-dependent peptidase activity
IUJ52_16280	COG0840	transmembrane signaling receptor activity
IUJ52_16285	COG2211	Major facilitator Superfamily
IUJ52_16290	COG0668	transmembrane transport
IUJ52_16295	COG0569	domain protein
IUJ52_16300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IUJ52_16310	COG3123	guanosine phosphorylase activity
IUJ52_16320	COG2814	Major facilitator Superfamily
IUJ52_16430	COG2205	protein histidine kinase activity
IUJ52_16435	COG0745	RESPONSE REGULATOR receiver
IUJ52_16440	COG1741	Belongs to the pirin family
IUJ52_16495	COG3706	GGDEF domain
IUJ52_16505	COG1846	Transcriptional regulator
IUJ52_16510	COG2315	Protein conserved in bacteria
IUJ52_16515	COG0835	chemotaxis
IUJ52_16515	COG0784	Response regulator, receiver
IUJ52_16520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ52_16545	COG1215	transferase activity, transferring glycosyl groups
IUJ52_16550	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IUJ52_16555	COG0367	asparagine synthase
IUJ52_16565	COG0251	oxidation-reduction process
IUJ52_16575	COG0583	DNA-binding transcription factor activity
IUJ52_16595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ52_16615	COG1522	sequence-specific DNA binding
IUJ52_16620	COG2197	response regulator
IUJ52_16625	COG0393	Putative heavy-metal-binding
IUJ52_16630	COG0823	Involved in the tonB-independent uptake of proteins
IUJ52_16635	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IUJ52_16640	COG0534	Mate efflux family protein
IUJ52_16650	COG1653	transport
IUJ52_16655	COG3842	ATPase activity
IUJ52_16660	COG0395	ABC-type sugar transport system, permease component
IUJ52_16665	COG1175	transmembrane transport
IUJ52_16680	COG0840	transmembrane signaling receptor activity
IUJ52_16690	COG0800	Aldolase
IUJ52_16695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ52_16705	COG0235	Class ii aldolase
IUJ52_16710	COG3254	rhamnose metabolic process
IUJ52_16715	COG4806	L-rhamnose isomerase
IUJ52_16720	COG1070	Carbohydrate kinase
IUJ52_16725	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
IUJ52_16755	COG1917	Cupin 2, conserved barrel domain protein
IUJ52_16765	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_16775	COG0517	IMP dehydrogenase activity
IUJ52_16795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IUJ52_16805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ52_16845	COG3842	ATPase activity
IUJ52_16855	COG1175	transmembrane transport
IUJ52_16860	COG3833	ABC-type maltose transport systems, permease component
IUJ52_16885	COG1349	DNA-binding transcription factor activity
IUJ52_16905	COG2354	Protein conserved in bacteria
IUJ52_16910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IUJ52_16915	COG0418	dihydroorotase activity
IUJ52_16920	COG0633	Ferredoxin
IUJ52_16920	COG3217	Mosc domain protein beta barrel domain protein
IUJ52_16950	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
IUJ52_16955	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ52_16965	COG0848	biopolymer transport protein
IUJ52_16970	COG0811	peptide transport
IUJ52_16975	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IUJ52_16985	COG3721	Heme iron utilization protein
IUJ52_16990	COG0748	coenzyme F420 binding
IUJ52_17000	COG0531	amino acid
IUJ52_17005	COG1522	sequence-specific DNA binding
IUJ52_17025	COG1151	hydroxylamine reductase activity
IUJ52_17030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ52_17035	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IUJ52_17060	COG0784	Response regulator, receiver
IUJ52_17060	COG2205	protein histidine kinase activity
IUJ52_17060	COG5002	protein histidine kinase activity
IUJ52_17080	COG1765	OsmC-like protein
IUJ52_17115	COG1765	OsmC-like protein
IUJ52_17125	COG0110	maltose O-acetyltransferase activity
IUJ52_17155	COG3121	Chaperone
IUJ52_17160	COG0579	oxidoreductase
IUJ52_17175	COG0583	DNA-binding transcription factor activity
IUJ52_17180	COG0798	PFAM Bile acid sodium symporter
IUJ52_17185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IUJ52_17195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IUJ52_17250	COG0513	Belongs to the DEAD box helicase family
IUJ52_17265	COG0840	transmembrane signaling receptor activity
IUJ52_17285	COG2985	domain, Protein
IUJ52_17295	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IUJ52_17340	COG3122	Protein conserved in bacteria
IUJ52_17345	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
IUJ52_17355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IUJ52_17360	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IUJ52_17360	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IUJ52_17365	COG0509	glycine decarboxylation via glycine cleavage system
IUJ52_17370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IUJ52_17380	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IUJ52_17395	COG3300	MHYT domain
IUJ52_17395	COG5001	Diguanylate cyclase
IUJ52_17400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ52_17440	COG0484	heat shock protein binding
IUJ52_17450	COG1716	ATPase activity
IUJ52_17450	COG5001	Diguanylate cyclase
IUJ52_17455	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IUJ52_17465	COG4181	ATPase activity
IUJ52_17470	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IUJ52_17480	COG1984	allophanate hydrolase subunit 2
IUJ52_17490	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IUJ52_17495	COG3447	MASE1 domain protein
IUJ52_17495	COG5001	Diguanylate cyclase
IUJ52_17495	COG5002	protein histidine kinase activity
IUJ52_17505	COG0840	transmembrane signaling receptor activity
IUJ52_17510	COG0814	amino acid
IUJ52_17515	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
IUJ52_17520	COG0513	Belongs to the DEAD box helicase family
IUJ52_17525	COG1309	transcriptional regulator
IUJ52_17535	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IUJ52_17550	COG2425	protein containing a von Willebrand factor type A (vWA) domain
IUJ52_17580	COG0840	transmembrane signaling receptor activity
IUJ52_17595	COG0583	DNA-binding transcription factor activity
IUJ52_17600	COG0697	spore germination
IUJ52_17625	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IUJ52_17640	COG0406	alpha-ribazole phosphatase activity
IUJ52_17645	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IUJ52_17650	COG1454	alcohol dehydrogenase
IUJ52_17655	COG1609	Transcriptional regulator
IUJ52_17655	COG2207	Transcriptional regulator
IUJ52_17670	COG3634	alkyl hydroperoxide reductase activity
IUJ52_17675	COG0450	alkyl hydroperoxide reductase
IUJ52_17690	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
IUJ52_17695	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IUJ52_17700	COG1960	acyl-CoA dehydrogenase activity
IUJ52_17710	COG0183	Belongs to the thiolase family
IUJ52_17720	COG1960	acyl-CoA dehydrogenase activity
IUJ52_17725	COG1024	Enoyl-CoA hydratase
IUJ52_17730	COG1024	Enoyl-CoA hydratase
IUJ52_17740	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_17750	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_17755	COG2211	Major facilitator Superfamily
IUJ52_17760	COG1397	ADP-ribosylglycohydrolase
IUJ52_17765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ52_17775	COG2188	Transcriptional regulator
IUJ52_17785	COG0653	protein targeting
IUJ52_17800	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IUJ52_17820	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IUJ52_17820	COG0512	Glutamine amidotransferase of anthranilate synthase
IUJ52_17825	COG1454	alcohol dehydrogenase
IUJ52_17830	COG1464	Belongs to the NlpA lipoprotein family
IUJ52_17865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IUJ52_17870	COG0625	glutathione transferase activity
IUJ52_17925	COG2721	sulfolactate sulfo-lyase activity
IUJ52_17940	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IUJ52_17950	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ52_17955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IUJ52_17960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ52_17980	COG1473	amidohydrolase
IUJ52_17995	COG1280	lysine exporter protein (LysE YggA)
IUJ52_18000	COG0400	carboxylic ester hydrolase activity
IUJ52_18005	COG0435	Glutathione S-transferase
IUJ52_18010	COG0583	DNA-binding transcription factor activity
IUJ52_18015	COG4145	pantothenate transmembrane transporter activity
IUJ52_18025	COG2423	ornithine cyclodeaminase activity
IUJ52_18040	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IUJ52_18065	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IUJ52_18075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IUJ52_18095	COG2207	Transcriptional regulator
IUJ52_18115	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IUJ52_18125	COG0488	(ABC) transporter
IUJ52_18195	COG0454	-acetyltransferase
IUJ52_18205	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IUJ52_18335	COG0515	serine threonine protein kinase
IUJ52_18440	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_18460	COG0010	Belongs to the arginase family
IUJ52_18475	COG1252	NADH dehydrogenase
IUJ52_18485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IUJ52_18490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IUJ52_18495	COG4232	protein-disulfide reductase activity
IUJ52_18505	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IUJ52_18510	COG0110	maltose O-acetyltransferase activity
IUJ52_18525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IUJ52_18525	COG3008	intermembrane lipid transfer
IUJ52_18530	COG2995	paraquat-inducible protein a
IUJ52_18535	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ52_18545	COG1012	belongs to the aldehyde dehydrogenase family
IUJ52_18550	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
IUJ52_18560	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IUJ52_18570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ52_18580	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IUJ52_18585	COG0583	DNA-binding transcription factor activity
IUJ52_18595	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IUJ52_18610	COG0513	Belongs to the DEAD box helicase family
IUJ52_18615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IUJ52_18635	COG0672	)-iron permease
IUJ52_18640	COG4633	Protein conserved in bacteria
IUJ52_18645	COG4628	conserved protein (DUF2132)
IUJ52_18690	COG0789	Transcriptional regulator
IUJ52_18695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ52_18750	COG0454	-acetyltransferase
IUJ52_18760	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_18795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IUJ52_18805	COG0494	nUDIX hydrolase
IUJ52_18810	COG1280	lysine exporter protein (LysE YggA)
IUJ52_18820	COG0456	acetyltransferase
IUJ52_18830	COG1335	isochorismatase
IUJ52_18860	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ52_18865	COG1309	transcriptional regulator
IUJ52_18875	COG0583	DNA-binding transcription factor activity
IUJ52_18885	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IUJ52_18900	COG2897	thiosulfate sulfurtransferase activity
IUJ52_18905	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IUJ52_18915	COG0302	gtp cyclohydrolase
IUJ52_18920	COG0531	amino acid
IUJ52_18930	COG4303	Ethanolamine ammonia lyase large subunit
IUJ52_18940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ52_18940	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IUJ52_18945	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IUJ52_18950	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IUJ52_18965	COG1011	Hydrolase
IUJ52_18970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IUJ52_18980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ52_18985	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ52_18990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IUJ52_19000	COG3842	ATPase activity
IUJ52_19020	COG2866	Carboxypeptidase
IUJ52_19045	COG4166	transmembrane transport
IUJ52_19050	COG4174	ABC transporter (Permease)
IUJ52_19055	COG4239	(ABC) transporter, permease
IUJ52_19060	COG4172	Belongs to the ABC transporter superfamily
IUJ52_19065	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IUJ52_19080	COG0784	Response regulator, receiver
IUJ52_19080	COG2205	protein histidine kinase activity
IUJ52_19085	COG4251	negative regulation of phosphorylation
IUJ52_19085	COG3706	GGDEF domain
IUJ52_19085	COG5001	Diguanylate cyclase
IUJ52_19085	COG2203	Gaf domain
IUJ52_19095	COG2199	diguanylate cyclase activity
IUJ52_19110	COG2501	S4 domain
IUJ52_19155	COG3710	Transcriptional regulator
IUJ52_19190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ52_19195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IUJ52_19195	COG2207	Transcriptional regulator
IUJ52_19205	COG2233	PERMEase
IUJ52_19230	COG0765	amino acid transport
IUJ52_19235	COG0765	amino acid transport
IUJ52_19265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IUJ52_19290	COG0402	S-adenosylhomocysteine deaminase activity
IUJ52_19295	COG2351	hydroxyisourate hydrolase activity
IUJ52_19325	COG1079	Belongs to the binding-protein-dependent transport system permease family
IUJ52_19330	COG4603	Belongs to the binding-protein-dependent transport system permease family
IUJ52_19335	COG3845	ABC transporter
IUJ52_19340	COG1309	transcriptional regulator
IUJ52_19360	COG2199	diguanylate cyclase activity
IUJ52_19375	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IUJ52_19380	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IUJ52_19405	COG3140	Belongs to the UPF0181 family
IUJ52_19420	COG0023	Translation Initiation Factor
IUJ52_19445	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IUJ52_19445	COG1042	CoA-binding domain protein
IUJ52_19445	COG0045	succinate-CoA ligase (ADP-forming) activity
IUJ52_19450	COG0583	DNA-binding transcription factor activity
IUJ52_19455	COG1629	transport
IUJ52_19455	COG4771	TonB-dependent receptor
IUJ52_19465	COG4533	DNA binding
IUJ52_19475	COG2050	protein possibly involved in aromatic compounds catabolism
IUJ52_19485	COG2824	Alkylphosphonate utilization operon protein PhnA
IUJ52_19500	COG0737	Belongs to the 5'-nucleotidase family
IUJ52_19505	COG3593	DNA synthesis involved in DNA repair
IUJ52_19515	COG0583	DNA-binding transcription factor activity
IUJ52_19520	COG2116	formate transmembrane transporter activity
IUJ52_19525	COG2353	YceI-like domain
IUJ52_19530	COG3038	cytochrome b561
IUJ52_19555	COG5001	Diguanylate cyclase
IUJ52_19565	COG0243	molybdopterin cofactor binding
IUJ52_19570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IUJ52_19575	COG2205	protein histidine kinase activity
IUJ52_19575	COG0784	Response regulator, receiver
IUJ52_19575	COG5002	protein histidine kinase activity
IUJ52_19580	COG3437	response regulator, receiver
IUJ52_19590	COG2207	Transcriptional regulator
IUJ52_19595	COG1064	alcohol dehydrogenase
IUJ52_19600	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ52_19605	COG1846	Transcriptional regulator
IUJ52_19610	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IUJ52_19615	COG0523	cobalamin synthesis protein
IUJ52_19630	COG0156	8-amino-7-oxononanoate synthase activity
IUJ52_19635	COG2205	protein histidine kinase activity
IUJ52_19635	COG0784	Response regulator, receiver
IUJ52_19640	COG0419	ATPase involved in DNA repair
IUJ52_19645	COG0420	3'-5' exonuclease activity
IUJ52_19650	COG1609	Transcriptional regulator
IUJ52_19655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ52_19655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ52_19660	COG1105	Belongs to the carbohydrate kinase PfkB family
IUJ52_19665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IUJ52_19665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IUJ52_19665	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IUJ52_19670	COG0189	ligase activity
IUJ52_19670	COG4067	protein conserved in archaea
IUJ52_19680	COG0602	queuosine metabolic process
IUJ52_19685	COG1328	CTP reductase activity
IUJ52_19730	COG0454	-acetyltransferase
IUJ52_19740	COG2207	Transcriptional regulator
IUJ52_19750	COG1073	alpha beta
IUJ52_19755	COG1073	alpha beta
IUJ52_19760	COG1902	pentaerythritol trinitrate reductase activity
IUJ52_19800	COG1566	PFAM secretion protein HlyD family protein
IUJ52_19805	COG0583	DNA-binding transcription factor activity
IUJ52_19810	COG1280	lysine exporter protein (LysE YggA)
IUJ52_19815	COG0745	RESPONSE REGULATOR receiver
IUJ52_19825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IUJ52_19830	COG0840	transmembrane signaling receptor activity
IUJ52_19845	COG0545	Peptidyl-prolyl cis-trans isomerase
IUJ52_19850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ52_19855	COG0840	transmembrane signaling receptor activity
IUJ52_19860	COG2814	Major facilitator Superfamily
IUJ52_19875	COG3069	C4-dicarboxylate transmembrane transporter activity
IUJ52_19880	COG2197	response regulator
IUJ52_19885	COG3850	Histidine kinase
IUJ52_19900	COG0243	molybdopterin cofactor binding
IUJ52_19910	COG3005	denitrification pathway
IUJ52_19920	COG4166	transmembrane transport
IUJ52_19940	COG0183	Belongs to the thiolase family
IUJ52_19950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ52_19955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ52_19980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IUJ52_19990	COG2207	Transcriptional regulator
IUJ52_19995	COG1979	alcohol dehydrogenase
IUJ52_20005	COG0784	Response regulator, receiver
IUJ52_20005	COG2198	Histidine kinase
IUJ52_20005	COG2205	protein histidine kinase activity
IUJ52_20010	COG1879	ABC-type sugar transport system periplasmic component
IUJ52_20015	COG1803	Methylglyoxal synthase
IUJ52_20020	COG1335	isochorismatase
IUJ52_20025	COG0210	DNA helicase
IUJ52_20065	COG1289	transmembrane transporter activity
IUJ52_20085	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IUJ52_20090	COG4149	molybdate abc transporter
IUJ52_20095	COG0725	ABC transporter, periplasmic molybdate-binding protein
IUJ52_20100	COG1492	cobalamin metabolic process
IUJ52_20120	COG5002	protein histidine kinase activity
IUJ52_20120	COG0784	Response regulator, receiver
IUJ52_20125	COG1879	ABC-type sugar transport system periplasmic component
IUJ52_20130	COG2827	Endonuclease containing a URI domain
IUJ52_20135	COG3132	Protein of unknown function, DUF480
IUJ52_20150	COG4974	Belongs to the 'phage' integrase family
IUJ52_20325	COG4695	Portal protein
IUJ52_20365	COG4386	tail sheath protein
IUJ52_20435	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IUJ52_20440	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IUJ52_20445	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IUJ52_20450	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
IUJ52_20455	COG0247	lactate metabolic process
IUJ52_20470	COG0438	transferase activity, transferring glycosyl groups
IUJ52_20470	COG0297	glycogen (starch) synthase activity
IUJ52_20475	COG0438	transferase activity, transferring glycosyl groups
IUJ52_20510	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IUJ52_20525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IUJ52_20530	COG3118	belongs to the thioredoxin family
IUJ52_20560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IUJ52_20560	COG1648	precorrin-2 dehydrogenase activity
IUJ52_20575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ52_20595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IUJ52_20600	COG4160	amino acid transport
IUJ52_20605	COG4215	(ABC) transporter
IUJ52_20610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ52_20615	COG1126	abc transporter atp-binding protein
IUJ52_20655	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IUJ52_20660	COG1120	ATPase activity
IUJ52_20670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IUJ52_20675	COG0583	DNA-binding transcription factor activity
IUJ52_20680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IUJ52_20695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ52_20705	COG1070	Carbohydrate kinase
IUJ52_20715	COG2390	Transcriptional regulator
IUJ52_20725	COG1294	oxidase, subunit
IUJ52_20730	COG1271	oxidase subunit
IUJ52_20740	COG3781	membrane
IUJ52_20745	COG0583	DNA-binding transcription factor activity
IUJ52_20750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IUJ52_20765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ52_20775	COG0330	HflC and HflK could
IUJ52_20795	COG1917	Cupin 2, conserved barrel domain protein
IUJ52_20795	COG2207	Transcriptional regulator
IUJ52_20805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IUJ52_20820	COG2207	Transcriptional regulator
IUJ52_20820	COG1609	Transcriptional regulator
IUJ52_20825	COG4604	ABC transporter, ATP-binding protein
IUJ52_20830	COG4605	iron ion homeostasis
IUJ52_20835	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ52_20845	COG0121	glutamine amidotransferase
IUJ52_20860	COG5380	lipid catabolic process
IUJ52_20865	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IUJ52_20870	COG0840	transmembrane signaling receptor activity
IUJ52_20875	COG1522	sequence-specific DNA binding
IUJ52_20895	COG2814	Major facilitator Superfamily
IUJ52_20905	COG0840	transmembrane signaling receptor activity
IUJ52_20920	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IUJ52_20925	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IUJ52_20930	COG3279	Response regulator of the LytR AlgR family
IUJ52_20935	COG3275	phosphorelay sensor kinase activity
IUJ52_20940	COG4989	oxidoreductase activity
IUJ52_20955	COG0366	Alpha amylase catalytic
IUJ52_20960	COG3227	Zinc metalloprotease (Elastase)
IUJ52_20965	COG3047	cAMP biosynthetic process
IUJ52_20975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IUJ52_20985	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IUJ52_21000	COG1482	cell wall glycoprotein biosynthetic process
IUJ52_21005	COG0840	transmembrane signaling receptor activity
IUJ52_21010	COG4580	involved in the transport of maltose and maltodextrins
IUJ52_21015	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
IUJ52_21020	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
IUJ52_21030	COG1609	Transcriptional regulator
IUJ52_21045	COG5578	integral membrane protein
IUJ52_21050	COG0395	ABC-type sugar transport system, permease component
IUJ52_21055	COG1175	transmembrane transport
IUJ52_21070	COG0351	phosphomethylpyrimidine kinase
IUJ52_21075	COG1116	anion transmembrane transporter activity
IUJ52_21080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ52_21085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ52_21090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IUJ52_21100	COG1132	(ABC) transporter
IUJ52_21105	COG1132	(ABC) transporter
IUJ52_21115	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IUJ52_21120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IUJ52_21140	COG1278	Cold shock
IUJ52_21145	COG1063	alcohol dehydrogenase
IUJ52_21150	COG0156	8-amino-7-oxononanoate synthase activity
IUJ52_21155	COG1012	belongs to the aldehyde dehydrogenase family
IUJ52_21160	COG3284	Transcriptional regulator
IUJ52_21170	COG0346	lactoylglutathione lyase activity
IUJ52_21190	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IUJ52_21200	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IUJ52_21205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IUJ52_21210	COG0363	glucosamine-6-phosphate deaminase activity
IUJ52_21215	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IUJ52_21255	COG0531	amino acid
IUJ52_21265	COG1929	Belongs to the glycerate kinase type-1 family
IUJ52_21270	COG2610	gluconate transmembrane transporter activity
IUJ52_21275	COG3835	regulator
IUJ52_21280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ52_21285	COG4533	DNA binding
IUJ52_21340	COG3188	usher protein
IUJ52_21345	COG3121	Chaperone
IUJ52_21355	COG3047	cAMP biosynthetic process
IUJ52_21355	COG2885	chlorophyll binding
IUJ52_21365	COG1566	PFAM secretion protein HlyD family protein
IUJ52_21380	COG1686	Belongs to the peptidase S11 family
IUJ52_21390	COG0765	amino acid transport
IUJ52_21405	COG1522	sequence-specific DNA binding
IUJ52_21410	COG0010	Belongs to the arginase family
IUJ52_21415	COG1166	arginine decarboxylase activity
IUJ52_21425	COG4175	Glycine betaine
IUJ52_21430	COG4176	ABC-type proline glycine betaine transport system permease component
IUJ52_21435	COG2113	Glycine betaine
IUJ52_21455	COG2239	Acts as a magnesium transporter
IUJ52_21460	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IUJ52_21465	COG0459	protein refolding
IUJ52_21475	COG0113	porphobilinogen synthase activity
IUJ52_21485	COG0784	Response regulator, receiver
IUJ52_21485	COG3437	response regulator, receiver
IUJ52_21510	COG0527	aspartate kinase activity
IUJ52_21515	COG0662	Cupin 2, conserved barrel domain protein
IUJ52_21520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ52_21525	COG0456	acetyltransferase
IUJ52_21535	COG0861	Integral membrane protein TerC family
IUJ52_21545	COG0534	Mate efflux family protein
IUJ52_21550	COG2154	pterin-4-alpha-carbinolamine dehydratase
IUJ52_21555	COG3186	Phenylalanine-4-hydroxylase
IUJ52_21560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ52_21625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IUJ52_21630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IUJ52_21630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IUJ52_21640	COG2197	response regulator
IUJ52_21645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ52_21645	COG2205	protein histidine kinase activity
IUJ52_21650	COG3300	MHYT domain
IUJ52_21650	COG5001	Diguanylate cyclase
IUJ52_21680	COG3036	rescue of stalled ribosome
IUJ52_21685	COG1278	Cold shock
IUJ52_21690	COG4681	YaeQ
IUJ52_21695	COG3706	GGDEF domain
IUJ52_21700	COG1017	nitric oxide dioxygenase activity
IUJ52_21700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ52_21705	COG3604	Transcriptional regulator
IUJ52_21715	COG2195	Cleaves the N-terminal amino acid of tripeptides
IUJ52_21720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IUJ52_21730	COG0366	Alpha amylase catalytic
IUJ52_21745	COG0840	transmembrane signaling receptor activity
IUJ52_21750	COG0714	Associated with various cellular activities
IUJ52_21770	COG2304	oxidoreductase activity
IUJ52_21785	COG5001	Diguanylate cyclase
IUJ52_21795	COG0784	Response regulator, receiver
IUJ52_21795	COG2205	protein histidine kinase activity
IUJ52_21795	COG5002	protein histidine kinase activity
IUJ52_21810	COG3724	N-succinylarginine dihydrolase activity
IUJ52_21815	COG1012	belongs to the aldehyde dehydrogenase family
IUJ52_21840	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ52_21865	COG0583	DNA-binding transcription factor activity
IUJ52_21890	COG3171	Protein conserved in bacteria
IUJ52_21895	COG0589	response to stress
IUJ52_21905	COG3530	Putative quorum-sensing-regulated virulence factor
IUJ52_21915	COG0579	oxidoreductase
IUJ52_21930	COG2204	response regulator
IUJ52_21960	COG3300	MHYT domain
IUJ52_21960	COG5001	Diguanylate cyclase
IUJ52_21965	COG2271	Major facilitator Superfamily
IUJ52_21970	COG0584	glycerophosphoryl diester phosphodiesterase
IUJ52_21975	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
IUJ52_21980	COG0583	DNA-binding transcription factor activity
IUJ52_21985	COG1609	Transcriptional regulator
IUJ52_21990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ52_21995	COG1879	ABC-type sugar transport system periplasmic component
IUJ52_22000	COG1172	Belongs to the binding-protein-dependent transport system permease family
IUJ52_22005	COG1129	ABC transporter
IUJ52_22010	COG1869	D-ribose catabolic process
IUJ52_22025	COG3409	Peptidoglycan-binding domain 1 protein
IUJ52_22025	COG3501	Rhs element vgr protein
IUJ52_22050	COG3829	transcription factor binding
IUJ52_22125	COG1846	Transcriptional regulator
IUJ52_22140	COG0564	pseudouridine synthase activity
IUJ52_22145	COG1309	transcriptional regulator
IUJ52_22150	COG2130	NADP-dependent
IUJ52_22165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ52_22195	COG3842	ATPase activity
IUJ52_22205	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IUJ52_22210	COG0656	L-ascorbic acid biosynthetic process
IUJ52_22215	COG1902	pentaerythritol trinitrate reductase activity
IUJ52_22220	COG0583	DNA-binding transcription factor activity
IUJ52_22225	COG2814	Major facilitator Superfamily
IUJ52_22245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IUJ52_22250	COG1360	Flagellar Motor Protein
IUJ52_22260	COG3188	usher protein
IUJ52_22265	COG3121	Chaperone
IUJ52_22310	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IUJ52_22320	COG4702	Belongs to the UPF0303 family
IUJ52_22325	COG0673	inositol 2-dehydrogenase activity
IUJ52_22330	COG1349	DNA-binding transcription factor activity
IUJ52_22340	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IUJ52_22360	COG3240	lipase activity
IUJ52_22365	COG3477	response to acidic pH
IUJ52_22370	COG0697	spore germination
IUJ52_22375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ52_22390	COG2207	Transcriptional regulator
IUJ52_22390	COG1917	Cupin 2, conserved barrel domain protein
IUJ52_22410	COG5002	protein histidine kinase activity
IUJ52_22410	COG5001	Diguanylate cyclase
IUJ52_22410	COG3447	MASE1 domain protein
IUJ52_22420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ52_22435	COG0109	protoheme IX farnesyltransferase activity
IUJ52_22470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUJ52_22475	COG1565	acr, cog1565
IUJ52_22475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IUJ52_22480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUJ52_22485	COG1902	pentaerythritol trinitrate reductase activity
IUJ52_22495	COG1280	lysine exporter protein (LysE YggA)
IUJ52_22515	COG0179	Fumarylacetoacetate (FAA) hydrolase
IUJ52_22520	COG1846	Transcriptional regulator
IUJ52_22525	COG1764	response to oxidative stress
IUJ52_22545	COG2814	Major facilitator Superfamily
IUJ52_22550	COG0583	DNA-binding transcription factor activity
IUJ52_22555	COG5001	Diguanylate cyclase
IUJ52_22560	COG0739	heme binding
IUJ52_22575	COG0659	secondary active sulfate transmembrane transporter activity
IUJ52_22580	COG3314	Sporulation integral membrane protein YlbJ
IUJ52_22590	COG2199	diguanylate cyclase activity
IUJ52_22595	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IUJ52_22600	COG0581	inorganic phosphate transmembrane transporter activity
IUJ52_22605	COG0573	inorganic phosphate transmembrane transporter activity
IUJ52_22610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IUJ52_22620	COG0513	Belongs to the DEAD box helicase family
IUJ52_22670	COG1376	ErfK ybiS ycfS ynhG family protein
IUJ52_22670	COG1388	LysM domain
IUJ52_22675	COG0415	Belongs to the DNA photolyase family
IUJ52_22680	COG0789	Transcriptional regulator
IUJ52_22685	COG3272	Protein of unknown function (DUF1722)
IUJ52_22690	COG0813	purine-nucleoside phosphorylase activity
IUJ52_22705	COG3706	GGDEF domain
IUJ52_22715	COG1566	PFAM secretion protein HlyD family protein
IUJ52_22750	COG0786	glutamate:sodium symporter activity
IUJ52_22775	COG1162	GTPase activity
IUJ52_22780	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IUJ52_22795	COG4580	involved in the transport of maltose and maltodextrins
IUJ52_22805	COG1132	(ABC) transporter
IUJ52_22825	COG3383	formate dehydrogenase (NAD+) activity
IUJ52_22840	COG0840	transmembrane signaling receptor activity
IUJ52_22850	COG1131	(ABC) transporter
IUJ52_22855	COG2188	Transcriptional regulator
IUJ52_22865	COG3033	Beta-eliminating lyase
IUJ52_22870	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IUJ52_22875	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IUJ52_22880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IUJ52_22885	COG0471	metal ion transport
IUJ52_22910	COG3788	relative of glutathione S-transferase, MAPEG superfamily
IUJ52_22930	COG3501	Rhs element vgr protein
IUJ52_22940	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IUJ52_22945	COG1640	4-alpha-glucanotransferase
IUJ52_22950	COG0058	SHG alpha-glucan phosphorylase activity
IUJ52_22955	COG2909	trisaccharide binding
IUJ52_22970	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IUJ52_22975	COG1845	cytochrome c oxidase, subunit III
IUJ52_22980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUJ52_22985	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IUJ52_23000	COG2084	Dehydrogenase
IUJ52_23015	COG0217	transcriptional regulatory protein
IUJ52_23045	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
IUJ52_23050	COG1444	tRNA N-acetyltransferase activity
IUJ52_23065	COG0643	Histidine kinase
IUJ52_23065	COG2198	Histidine kinase
IUJ52_23070	COG0835	chemotaxis
IUJ52_23075	COG0835	chemotaxis
IUJ52_23080	COG0840	transmembrane signaling receptor activity
IUJ52_23085	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IUJ52_23090	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
IUJ52_23095	COG2201	protein-glutamate methylesterase activity
IUJ52_23110	COG0745	RESPONSE REGULATOR receiver
IUJ52_23130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IUJ52_23165	COG0840	transmembrane signaling receptor activity
IUJ52_23190	COG0513	Belongs to the DEAD box helicase family
IUJ52_23200	COG0583	DNA-binding transcription factor activity
IUJ52_23205	COG2226	methyltransferase
IUJ52_23220	COG0724	RNA recognition motif
IUJ52_23225	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IUJ52_23230	COG1522	sequence-specific DNA binding
IUJ52_23235	COG2610	gluconate transmembrane transporter activity
IUJ52_23240	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ52_23245	COG3622	Belongs to the hyi family
IUJ52_23250	COG0235	Class ii aldolase
IUJ52_23255	COG3395	kinase activity
IUJ52_23260	COG2084	Dehydrogenase