locus-tag	class	description
LUM42_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LUM42_00010	COG0592	DNA-directed DNA polymerase activity
LUM42_00020	COG0187	DNA topoisomerase II activity
LUM42_00030	COG0071	Belongs to the small heat shock protein (HSP20) family
LUM42_00035	COG3977	Valine--pyruvate aminotransferase
LUM42_00040	COG0751	glycine-tRNA ligase activity
LUM42_00045	COG0752	glycyl-tRNA synthetase alpha subunit
LUM42_00050	COG2119	membrane
LUM42_00060	COG0425	Belongs to the sulfur carrier protein TusA family
LUM42_00090	COG0604	alcohol dehydrogenase
LUM42_00105	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LUM42_00110	COG3978	acetolactate synthase activity
LUM42_00215	COG1196	nuclear chromosome segregation
LUM42_00225	COG0204	Acyl-transferase
LUM42_00230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LUM42_00235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LUM42_00245	COG3084	Protein conserved in bacteria
LUM42_00250	COG4326	sporulation control protein
LUM42_00255	COG1272	protein, Hemolysin III
LUM42_00265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LUM42_00270	COG0569	domain protein
LUM42_00275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LUM42_00275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LUM42_00295	COG0758	DNA mediated transformation
LUM42_00300	COG2922	Belongs to the Smg family
LUM42_00305	COG0551	DNA topoisomerase type I activity
LUM42_00310	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LUM42_00315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LUM42_00325	COG0408	coproporphyrinogen oxidase activity
LUM42_00330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LUM42_00340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LUM42_00380	COG0583	DNA-binding transcription factor activity
LUM42_00385	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LUM42_00390	COG2960	long-chain fatty acid transporting porin activity
LUM42_00395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUM42_00400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_00405	COG1309	transcriptional regulator
LUM42_00450	COG0747	negative chemotaxis
LUM42_00455	COG0601	transmembrane transport
LUM42_00460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUM42_00495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUM42_00500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_00515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LUM42_00520	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LUM42_00555	COG0210	DNA helicase
LUM42_00560	COG0405	Gamma-glutamyltransferase
LUM42_00565	COG1280	lysine exporter protein (LysE YggA)
LUM42_00575	COG2962	Rard protein
LUM42_00580	COG0514	ATP-dependent DNA helicase (RecQ)
LUM42_00595	COG1132	(ABC) transporter
LUM42_00600	COG4774	siderophore transport
LUM42_00605	COG1120	ATPase activity
LUM42_00610	COG4607	ABC-type enterochelin transport system periplasmic component
LUM42_00620	COG2862	Uncharacterized protein family, UPF0114
LUM42_00650	COG0328	RNA-DNA hybrid ribonuclease activity
LUM42_00655	COG1968	undecaprenyl-diphosphatase activity
LUM42_00665	COG0668	transmembrane transport
LUM42_00670	COG1742	UPF0060 membrane protein
LUM42_00685	COG1279	arginine transmembrane transporter activity
LUM42_00715	COG2003	Belongs to the UPF0758 family
LUM42_00740	COG0671	phosphoesterase, PA-phosphatase related
LUM42_00745	COG2194	sulfuric ester hydrolase activity
LUM42_00750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LUM42_00755	COG0745	RESPONSE REGULATOR receiver
LUM42_00760	COG5002	protein histidine kinase activity
LUM42_00770	COG1561	YicC-like family, N-terminal region
LUM42_00775	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LUM42_00780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LUM42_00785	COG1560	Kdo2-lipid A biosynthetic process
LUM42_00790	COG1309	transcriptional regulator
LUM42_00805	COG2003	Belongs to the UPF0758 family
LUM42_00810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LUM42_00815	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LUM42_00825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LUM42_00840	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LUM42_00845	COG0438	transferase activity, transferring glycosyl groups
LUM42_00850	COG0438	transferase activity, transferring glycosyl groups
LUM42_00855	COG0463	Glycosyl transferase, family 2
LUM42_00860	COG0859	PFAM glycosyl transferase family 9
LUM42_00865	COG3642	lipopolysaccharide core region biosynthetic process
LUM42_00870	COG1519	Transferase
LUM42_00875	COG0859	PFAM glycosyl transferase family 9
LUM42_00880	COG0438	transferase activity, transferring glycosyl groups
LUM42_00890	COG1560	Kdo2-lipid A biosynthetic process
LUM42_00900	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LUM42_00905	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUM42_00935	COG3206	protein involved in exopolysaccharide biosynthesis
LUM42_00935	COG0489	protein tyrosine kinase activity
LUM42_00955	COG5433	transposase activity
LUM42_00975	COG5433	transposase activity
LUM42_00985	COG2089	acid synthase
LUM42_01020	COG5433	transposase activity
LUM42_01030	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LUM42_01050	COG1879	ABC-type sugar transport system periplasmic component
LUM42_01065	COG0582	viral genome integration into host DNA
LUM42_01130	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LUM42_01165	COG1573	uracil-dna glycosylase
LUM42_01170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUM42_01175	COG3068	Protein conserved in bacteria
LUM42_01180	COG0668	transmembrane transport
LUM42_01185	COG1253	flavin adenine dinucleotide binding
LUM42_01190	COG0776	regulation of translation
LUM42_01200	COG0151	Belongs to the GarS family
LUM42_01205	COG0138	bifunctional purine biosynthesis protein purh
LUM42_01215	COG0789	Transcriptional regulator
LUM42_01220	COG1940	carbohydrate kinase activity
LUM42_01230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUM42_01230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUM42_01230	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_01235	COG2207	Transcriptional regulator
LUM42_01250	COG0840	transmembrane signaling receptor activity
LUM42_01285	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LUM42_01290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LUM42_01295	COG2264	protein methyltransferase activity
LUM42_01300	COG0439	Biotin carboxylase
LUM42_01305	COG0511	ligase activity, forming carbon-carbon bonds
LUM42_01310	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LUM42_01315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUM42_01330	COG2814	Major facilitator Superfamily
LUM42_01335	COG2205	protein histidine kinase activity
LUM42_01335	COG0784	Response regulator, receiver
LUM42_01335	COG2198	Histidine kinase
LUM42_01335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_01340	COG0248	Ppx GppA phosphatase
LUM42_01345	COG0513	Belongs to the DEAD box helicase family
LUM42_01350	COG3118	belongs to the thioredoxin family
LUM42_01365	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LUM42_01410	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LUM42_01420	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LUM42_01430	COG1072	(Pantothenic acid kinase))
LUM42_01460	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LUM42_01465	COG0250	Participates in transcription elongation, termination and antitermination
LUM42_01480	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LUM42_01485	COG0222	ribosome binding
LUM42_01490	COG0085	RNA polymerase activity
LUM42_01495	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LUM42_01500	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LUM42_01505	COG2816	NAD+ diphosphatase activity
LUM42_01510	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LUM42_01525	COG4942	peptidase
LUM42_01530	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LUM42_01540	COG0840	transmembrane signaling receptor activity
LUM42_01545	COG0471	metal ion transport
LUM42_01545	COG0490	domain, Protein
LUM42_01550	COG0688	phosphatidylethanolamine metabolic process
LUM42_01555	COG1162	GTPase activity
LUM42_01610	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LUM42_01615	COG0802	atpase or kinase
LUM42_01625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LUM42_01630	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LUM42_01640	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LUM42_01645	COG0330	HflC and HflK could
LUM42_01650	COG0330	HflC and HflK could
LUM42_01655	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LUM42_01660	COG2900	Belongs to the SlyX family
LUM42_01670	COG0545	Peptidyl-prolyl cis-trans isomerase
LUM42_01675	COG2964	Protein conserved in bacteria
LUM42_01685	COG2923	Belongs to the DsrF TusC family
LUM42_01690	COG2168	tRNA wobble position uridine thiolation
LUM42_01700	COG0049	tRNA binding
LUM42_01705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LUM42_01715	COG2906	2 iron, 2 sulfur cluster binding
LUM42_01725	COG0360	Binds together with S18 to 16S ribosomal RNA
LUM42_01730	COG2965	DNA replication, synthesis of RNA primer
LUM42_01740	COG0359	binds to the 23S rRNA
LUM42_01755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LUM42_01765	COG0166	Belongs to the GPI family
LUM42_01775	COG0735	belongs to the Fur family
LUM42_01780	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LUM42_01800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LUM42_01810	COG0175	sulfate reduction
LUM42_01875	COG0646	methionine synthase
LUM42_01875	COG1410	methionine synthase
LUM42_01880	COG0527	aspartate kinase activity
LUM42_01885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LUM42_01895	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LUM42_01910	COG0629	single-stranded DNA binding
LUM42_01915	COG2200	EAL domain
LUM42_01915	COG2199	diguanylate cyclase activity
LUM42_01940	COG3409	Peptidoglycan-binding domain 1 protein
LUM42_01940	COG3267	Type II secretory pathway component ExeA
LUM42_01950	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LUM42_01955	COG1459	type II secretion system
LUM42_01965	COG2165	general secretion pathway protein
LUM42_01970	COG2165	general secretion pathway protein
LUM42_02000	COG1077	Cell shape determining protein MreB Mrl
LUM42_02005	COG1792	Involved in formation and maintenance of cell shape
LUM42_02010	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LUM42_02015	COG0424	maF-like protein
LUM42_02020	COG1530	ribonuclease E activity
LUM42_02025	COG3164	Protein of unknown function
LUM42_02030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUM42_02035	COG0312	modulator of DNA gyrase
LUM42_02055	COG0589	response to stress
LUM42_02070	COG1438	arginine binding
LUM42_02075	COG0039	L-malate dehydrogenase activity
LUM42_02080	COG0531	amino acid
LUM42_02085	COG0142	geranyltranstransferase activity
LUM42_02090	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LUM42_02100	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LUM42_02105	COG2966	Psort location CytoplasmicMembrane, score
LUM42_02110	COG3610	response to peptide
LUM42_02120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LUM42_02125	COG2967	ApaG domain
LUM42_02130	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LUM42_02135	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LUM42_02140	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LUM42_02145	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LUM42_02150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LUM42_02200	COG0741	lytic transglycosylase activity
LUM42_02205	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LUM42_02215	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LUM42_02220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_02225	COG1120	ATPase activity
LUM42_02230	COG1194	a g-specific adenine glycosylase
LUM42_02235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LUM42_02240	COG2066	Belongs to the glutaminase family
LUM42_02245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LUM42_02250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LUM42_02260	COG1872	DUF167
LUM42_02265	COG0762	integral membrane protein
LUM42_02270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LUM42_02275	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LUM42_02290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LUM42_02295	COG1678	Uncharacterized ACR, COG1678
LUM42_02300	COG0189	ligase activity
LUM42_02305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LUM42_02310	COG2356	endonuclease I
LUM42_02325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LUM42_02330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LUM42_02335	COG0583	DNA-binding transcription factor activity
LUM42_02340	COG4771	TonB-dependent receptor
LUM42_02345	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LUM42_02350	COG0126	phosphoglycerate kinase activity
LUM42_02355	COG0191	fructose-bisphosphate aldolase activity
LUM42_02360	COG0668	transmembrane transport
LUM42_02370	COG1279	arginine transmembrane transporter activity
LUM42_02395	COG1349	DNA-binding transcription factor activity
LUM42_02400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LUM42_02415	COG2239	Acts as a magnesium transporter
LUM42_02425	COG1609	Transcriptional regulator
LUM42_02430	COG1263	PTS System
LUM42_02430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_02435	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LUM42_02445	COG2378	regulation of single-species biofilm formation
LUM42_02460	COG1278	Cold shock
LUM42_02515	COG0358	DNA primase activity
LUM42_02520	COG1610	YqeY-like protein
LUM42_02525	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LUM42_02530	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LUM42_02540	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LUM42_02545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LUM42_02550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LUM42_02555	COG1968	undecaprenyl-diphosphatase activity
LUM42_02560	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LUM42_02565	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LUM42_02575	COG0585	pseudouridine synthase activity
LUM42_02580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LUM42_02585	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LUM42_02590	COG1388	LysM domain
LUM42_02590	COG4942	peptidase
LUM42_02595	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUM42_02600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LUM42_02605	COG1546	Belongs to the CinA family
LUM42_02610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LUM42_02615	COG2137	regulation of response to DNA damage stimulus
LUM42_02620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LUM42_02625	COG0527	aspartate kinase activity
LUM42_02675	COG3630	sodium ion export across plasma membrane
LUM42_02680	COG5016	pyruvate
LUM42_02680	COG0511	ligase activity, forming carbon-carbon bonds
LUM42_02685	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
LUM42_02695	COG1238	metal cluster binding
LUM42_02700	COG0612	Peptidase, M16
LUM42_02705	COG2918	glutathione biosynthetic process
LUM42_02715	COG1854	S-ribosylhomocysteine lyase activity
LUM42_02720	COG4536	flavin adenine dinucleotide binding
LUM42_02725	COG4137	Cytochrome C assembly protein
LUM42_02730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LUM42_02740	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LUM42_02745	COG0336	Belongs to the RNA methyltransferase TrmD family
LUM42_02750	COG0335	large ribosomal subunit rRNA binding
LUM42_02755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUM42_02760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LUM42_02765	COG3105	Protein conserved in bacteria
LUM42_02770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LUM42_02775	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LUM42_02780	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LUM42_02785	COG0723	plastoquinol--plastocyanin reductase activity
LUM42_02790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LUM42_02795	COG2857	Cytochrome c1
LUM42_02800	COG0625	glutathione transferase activity
LUM42_02805	COG2969	positive regulation of protein catabolic process
LUM42_02810	COG2823	Periplasmic or secreted lipoprotein
LUM42_02815	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LUM42_02820	COG0792	nuclease activity
LUM42_02825	COG3107	peptidoglycan biosynthetic process
LUM42_02830	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LUM42_02845	COG3116	cell division
LUM42_02850	COG0768	penicillin binding
LUM42_02855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LUM42_02860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LUM42_02870	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LUM42_02875	COG0772	Belongs to the SEDS family
LUM42_02880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LUM42_02885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LUM42_02890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LUM42_02895	COG0849	cell division
LUM42_02900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LUM42_02905	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LUM42_02915	COG0653	protein targeting
LUM42_02920	COG0494	nUDIX hydrolase
LUM42_02925	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LUM42_02930	COG0505	Belongs to the CarA family
LUM42_02935	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LUM42_02945	COG3479	Phenolic acid decarboxylase
LUM42_02950	COG0730	response to heat
LUM42_02955	COG0583	DNA-binding transcription factor activity
LUM42_02975	COG2860	membrane
LUM42_02980	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LUM42_02990	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LUM42_03000	COG0493	'glutamate synthase
LUM42_03005	COG0067	glutamate synthase
LUM42_03005	COG0069	glutamate synthase activity
LUM42_03005	COG0070	glutamate synthase
LUM42_03015	COG0069	glutamate synthase activity
LUM42_03015	COG0070	glutamate synthase
LUM42_03015	COG0067	glutamate synthase
LUM42_03020	COG1242	4 iron, 4 sulfur cluster binding
LUM42_03025	COG4251	negative regulation of phosphorylation
LUM42_03025	COG3706	GGDEF domain
LUM42_03025	COG5001	Diguanylate cyclase
LUM42_03025	COG2203	Gaf domain
LUM42_03030	COG5002	protein histidine kinase activity
LUM42_03030	COG2198	Histidine kinase
LUM42_03030	COG0784	Response regulator, receiver
LUM42_03040	COG0745	RESPONSE REGULATOR receiver
LUM42_03050	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUM42_03065	COG0083	homoserine kinase activity
LUM42_03070	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LUM42_03075	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LUM42_03090	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LUM42_03105	COG1115	amino acid carrier protein
LUM42_03110	COG3022	response to hydroperoxide
LUM42_03120	COG0084	hydrolase, TatD family'
LUM42_03125	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LUM42_03135	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LUM42_03140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LUM42_03145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LUM42_03150	COG0813	purine-nucleoside phosphorylase activity
LUM42_03160	COG0560	Phosphoserine phosphatase
LUM42_03170	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LUM42_03175	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LUM42_03180	COG0583	DNA-binding transcription factor activity
LUM42_03190	COG0583	DNA-binding transcription factor activity
LUM42_03195	COG1022	Amp-dependent synthetase and ligase
LUM42_03230	COG4964	Belongs to the GSP D family
LUM42_03285	COG2059	Chromate
LUM42_03290	COG2017	converts alpha-aldose to the beta-anomer
LUM42_03295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUM42_03325	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LUM42_03330	COG2171	N-acyltransferase activity
LUM42_03335	COG3141	response to X-ray
LUM42_03340	COG0583	DNA-binding transcription factor activity
LUM42_03350	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LUM42_03355	COG1074	ATP-dependent DNA helicase activity
LUM42_03360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LUM42_03370	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LUM42_03370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LUM42_03380	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LUM42_03385	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LUM42_03390	COG2166	iron-sulfur cluster assembly
LUM42_03395	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LUM42_03400	COG0693	protein deglycase activity
LUM42_03405	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LUM42_03410	COG3248	Nucleoside-binding outer membrane protein
LUM42_03420	COG1595	DNA-templated transcription, initiation
LUM42_03430	COG0477	Major facilitator Superfamily
LUM42_03435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LUM42_03440	COG0826	peptidase U32
LUM42_03450	COG0745	RESPONSE REGULATOR receiver
LUM42_03455	COG5002	protein histidine kinase activity
LUM42_03465	COG0248	Ppx GppA phosphatase
LUM42_03470	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LUM42_03475	COG0573	inorganic phosphate transmembrane transporter activity
LUM42_03480	COG0581	inorganic phosphate transmembrane transporter activity
LUM42_03485	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LUM42_03490	COG0704	Plays a role in the regulation of phosphate uptake
LUM42_03500	COG3142	Participates in the control of copper homeostasis
LUM42_03505	COG0450	alkyl hydroperoxide reductase
LUM42_03510	COG0583	DNA-binding transcription factor activity
LUM42_03515	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LUM42_03530	COG0517	IMP dehydrogenase activity
LUM42_03535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LUM42_03545	COG1862	Preprotein translocase
LUM42_03550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUM42_03555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUM42_03560	COG1335	isochorismatase
LUM42_03565	COG0483	inositol monophosphate 1-phosphatase activity
LUM42_03570	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LUM42_03575	COG1959	2 iron, 2 sulfur cluster binding
LUM42_03580	COG1104	cysteine desulfurase activity
LUM42_03585	COG0822	iron-sulfur transferase activity
LUM42_03600	COG0443	Heat shock 70 kDa protein
LUM42_03605	COG0633	Ferredoxin
LUM42_03610	COG2975	iron-sulfur cluster assembly
LUM42_03615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LUM42_03620	COG0105	UTP biosynthetic process
LUM42_03635	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LUM42_03640	COG0124	histidyl-tRNA synthetase
LUM42_03645	COG2976	Protein conserved in bacteria
LUM42_03650	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUM42_03655	COG1160	GTP binding
LUM42_03670	COG1570	exodeoxyribonuclease VII activity
LUM42_03675	COG0516	GMP reductase activity
LUM42_03675	COG0517	IMP dehydrogenase activity
LUM42_03680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LUM42_03680	COG0519	Catalyzes the synthesis of GMP from XMP
LUM42_03690	COG1584	GPR1 FUN34 yaaH family protein
LUM42_03700	COG3710	Transcriptional regulator
LUM42_03710	COG3188	usher protein
LUM42_03715	COG3121	Chaperone
LUM42_03735	COG1115	amino acid carrier protein
LUM42_03750	COG0583	DNA-binding transcription factor activity
LUM42_03755	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LUM42_03785	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LUM42_03790	COG2867	negative regulation of translational initiation
LUM42_03795	COG2914	Belongs to the UPF0125 (RnfH) family
LUM42_03800	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUM42_03805	COG0497	DNA recombination
LUM42_03810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LUM42_03815	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LUM42_03825	COG0443	Heat shock 70 kDa protein
LUM42_03830	COG0484	heat shock protein binding
LUM42_03840	COG4969	Belongs to the N-Me-Phe pilin family
LUM42_03860	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LUM42_03865	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LUM42_03875	COG0583	DNA-binding transcription factor activity
LUM42_03885	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LUM42_03890	COG0047	phosphoribosylformylglycinamidine synthase activity
LUM42_03890	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LUM42_03915	COG0442	prolyl-tRNA aminoacylation
LUM42_03920	COG1720	tRNA m6t6A37 methyltransferase activity
LUM42_03925	COG0254	rRNA binding
LUM42_03930	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LUM42_03935	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LUM42_03940	COG1671	Belongs to the UPF0178 family
LUM42_03965	COG3098	single-species biofilm formation
LUM42_03970	COG0564	pseudouridine synthase activity
LUM42_03975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LUM42_03980	COG0142	geranyltranstransferase activity
LUM42_03985	COG1722	exodeoxyribonuclease VII activity
LUM42_03990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LUM42_04000	COG0301	tRNA thio-modification
LUM42_04000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUM42_04005	COG0583	DNA-binding transcription factor activity
LUM42_04015	COG2363	Small membrane protein
LUM42_04025	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LUM42_04030	COG1611	Belongs to the LOG family
LUM42_04045	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LUM42_04045	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LUM42_04055	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
LUM42_04060	COG1464	Belongs to the NlpA lipoprotein family
LUM42_04065	COG2011	ABC-type metal ion transport system permease component
LUM42_04070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LUM42_04075	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LUM42_04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_04090	COG1263	PTS System
LUM42_04095	COG0366	Alpha amylase catalytic
LUM42_04100	COG2271	Major facilitator Superfamily
LUM42_04105	COG3851	Histidine kinase
LUM42_04110	COG2197	response regulator
LUM42_04140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_04145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUM42_04155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LUM42_04165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LUM42_04170	COG0321	lipoyl(octanoyl) transferase activity
LUM42_04175	COG2921	Belongs to the UPF0250 family
LUM42_04180	COG1686	Belongs to the peptidase S11 family
LUM42_04185	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LUM42_04190	COG0772	Belongs to the SEDS family
LUM42_04195	COG0768	penicillin binding
LUM42_04200	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LUM42_04205	COG0799	negative regulation of ribosome biogenesis
LUM42_04210	COG1466	dna polymerase III delta subunit
LUM42_04215	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LUM42_04220	COG0495	leucyl-tRNA aminoacylation
LUM42_04225	COG2888	peptidyl-tyrosine sulfation
LUM42_04230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LUM42_04235	COG4535	Mg2 and Co2 transporter CorC
LUM42_04240	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LUM42_04245	COG1702	phosphate starvation-inducible protein PhoH
LUM42_04250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LUM42_04255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUM42_04260	COG2190	(PTS) system
LUM42_04270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_04275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LUM42_04280	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LUM42_04285	COG3115	cell septum assembly
LUM42_04290	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LUM42_04305	COG0789	Transcriptional regulator
LUM42_04315	COG0330	HflC and HflK could
LUM42_04320	COG3118	belongs to the thioredoxin family
LUM42_04325	COG0300	oxidoreductase activity
LUM42_04330	COG1090	epimerase
LUM42_04355	COG0622	Phosphoesterase
LUM42_04370	COG3710	Transcriptional regulator
LUM42_04385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LUM42_04400	COG0367	asparagine synthase
LUM42_04405	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LUM42_04405	COG4651	solute:proton antiporter activity
LUM42_04410	COG1846	Transcriptional regulator
LUM42_04410	COG1940	carbohydrate kinase activity
LUM42_04415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LUM42_04420	COG2190	(PTS) system
LUM42_04420	COG1263	PTS System
LUM42_04420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_04435	COG0101	tRNA pseudouridine synthase activity
LUM42_04440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LUM42_04445	COG0285	dihydrofolate synthase activity
LUM42_04450	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LUM42_04455	COG1286	toxin biosynthetic process
LUM42_04460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LUM42_04465	COG2056	Na+-H+ antiporter family
LUM42_04470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LUM42_04485	COG0346	lactoylglutathione lyase activity
LUM42_04490	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LUM42_04495	COG4660	Part of a membrane complex involved in electron transport
LUM42_04500	COG4659	FMN binding
LUM42_04505	COG4658	electron transport chain
LUM42_04510	COG4656	Part of a membrane complex involved in electron transport
LUM42_04515	COG2878	Part of a membrane complex involved in electron transport
LUM42_04520	COG4657	Part of a membrane complex involved in electron transport
LUM42_04525	COG1882	Formate acetyltransferase
LUM42_04535	COG0556	nucleotide-excision repair
LUM42_04540	COG2204	response regulator
LUM42_04545	COG2198	Histidine kinase
LUM42_04550	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LUM42_04555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LUM42_04560	COG0521	Mo-molybdopterin cofactor biosynthetic process
LUM42_04565	COG0315	cyclic pyranopterin monophosphate synthase activity
LUM42_04570	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LUM42_04575	COG0314	molybdopterin synthase activity
LUM42_04580	COG3706	GGDEF domain
LUM42_04585	COG0517	IMP dehydrogenase activity
LUM42_04585	COG0617	tRNA 3'-terminal CCA addition
LUM42_04585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LUM42_04595	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
LUM42_04605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUM42_04605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUM42_04615	COG0572	uridine kinase
LUM42_04620	COG2982	Protein involved in outer membrane biogenesis
LUM42_04625	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LUM42_04645	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LUM42_04650	COG2067	long-chain fatty acid transport protein
LUM42_04670	COG0183	Belongs to the thiolase family
LUM42_04675	COG1024	Enoyl-CoA hydratase
LUM42_04675	COG1250	3-hydroxyacyl-CoA dehydrogenase
LUM42_04680	COG0778	Nitroreductase
LUM42_04685	COG0583	DNA-binding transcription factor activity
LUM42_04690	COG0745	RESPONSE REGULATOR receiver
LUM42_04695	COG2832	Protein of unknown function (DUF454)
LUM42_04700	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LUM42_04710	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LUM42_04715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LUM42_04720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LUM42_04730	COG2983	Belongs to the UPF0260 family
LUM42_04745	COG2226	methyltransferase
LUM42_04750	COG0676	glucose-6-phosphate 1-epimerase activity
LUM42_04755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LUM42_04760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUM42_04770	COG3139	Protein of unknown function (DUF1315)
LUM42_04775	COG0252	asparaginase activity
LUM42_04780	COG0616	signal peptide processing
LUM42_04785	COG0446	pyridine nucleotide-disulphide oxidoreductase
LUM42_04785	COG1902	pentaerythritol trinitrate reductase activity
LUM42_04790	COG0788	formyltetrahydrofolate deformylase activity
LUM42_04800	COG1199	ATP-dependent helicase activity
LUM42_04805	COG1214	PFAM Peptidase M22, glycoprotease
LUM42_04820	COG2267	carboxylic ester hydrolase activity
LUM42_04825	COG0318	PFAM AMP-dependent synthetase and ligase
LUM42_04830	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LUM42_04840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LUM42_04845	COG2894	cell division
LUM42_04850	COG0850	regulation of cytokinetic process
LUM42_04855	COG3100	YcgL domain-containing protein
LUM42_04860	COG2951	lytic endotransglycosylase activity
LUM42_04870	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LUM42_04875	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LUM42_04890	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LUM42_04895	COG2211	Major facilitator Superfamily
LUM42_04940	COG4589	Belongs to the CDS family
LUM42_04960	COG3153	acetyltransferase
LUM42_04960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LUM42_04970	COG1760	l-serine dehydratase
LUM42_04975	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LUM42_04995	COG1404	Belongs to the peptidase S8 family
LUM42_05000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LUM42_05005	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LUM42_05010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LUM42_05015	COG2204	response regulator
LUM42_05020	COG4191	Histidine kinase
LUM42_05030	COG0544	peptidyl-prolyl cis-trans isomerase activity
LUM42_05040	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LUM42_05045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LUM42_05050	COG0776	regulation of translation
LUM42_05055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LUM42_05060	COG1555	photosystem II stabilization
LUM42_05065	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LUM42_05070	COG0539	negative regulation of cytoplasmic translation
LUM42_05075	COG0776	regulation of translation
LUM42_05080	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LUM42_05085	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LUM42_05105	COG0583	DNA-binding transcription factor activity
LUM42_05115	COG0686	Belongs to the AlaDH PNT family
LUM42_05120	COG1522	sequence-specific DNA binding
LUM42_05125	COG1674	ftsk spoiiie
LUM42_05130	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LUM42_05135	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LUM42_05140	COG2186	Transcriptional regulator
LUM42_05155	COG0537	adenosine 5'-monophosphoramidase activity
LUM42_05180	COG3150	esterase
LUM42_05185	COG1252	NADH dehydrogenase
LUM42_05200	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LUM42_05210	COG4591	ABC-type transport system involved in lipoprotein release permease component
LUM42_05215	COG1136	(ABC) transporter
LUM42_05220	COG4591	ABC-type transport system involved in lipoprotein release permease component
LUM42_05230	COG2333	competence protein COMEC
LUM42_05230	COG0658	competence protein
LUM42_05235	COG1132	(ABC) transporter
LUM42_05240	COG1663	tetraacyldisaccharide 4'-kinase activity
LUM42_05250	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LUM42_05255	COG2719	SpoVR family
LUM42_05260	COG2718	Belongs to the UPF0229 family
LUM42_05265	COG2766	serine protein kinase
LUM42_05270	COG3713	MltA-interacting MipA family protein
LUM42_05275	COG3013	Belongs to the UPF0304 family
LUM42_05285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LUM42_05300	COG1882	Formate acetyltransferase
LUM42_05325	COG4160	amino acid transport
LUM42_05330	COG0708	Exodeoxyribonuclease III
LUM42_05335	COG0840	transmembrane signaling receptor activity
LUM42_05345	COG3923	Primosomal replication protein n
LUM42_05350	COG1199	ATP-dependent helicase activity
LUM42_05355	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LUM42_05360	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LUM42_05365	COG3012	SEC-C Motif Domain Protein
LUM42_05370	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LUM42_05375	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LUM42_05380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LUM42_05385	COG0215	cysteine-tRNA ligase activity
LUM42_05390	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LUM42_05395	COG0632	four-way junction helicase activity
LUM42_05400	COG2255	four-way junction helicase activity
LUM42_05405	COG1271	oxidase subunit
LUM42_05410	COG1294	oxidase, subunit
LUM42_05415	COG4890	Cyd operon protein YbgT
LUM42_05425	COG0824	Thioesterase
LUM42_05430	COG0811	peptide transport
LUM42_05445	COG0823	Involved in the tonB-independent uptake of proteins
LUM42_05450	COG2885	chlorophyll binding
LUM42_05455	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LUM42_05460	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LUM42_05470	COG0784	Response regulator, receiver
LUM42_05470	COG5002	protein histidine kinase activity
LUM42_05495	COG3366	ferrous iron transmembrane transporter activity
LUM42_05500	COG0700	Nucleoside recognition
LUM42_05505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUM42_05510	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_05530	COG1960	acyl-CoA dehydrogenase activity
LUM42_05535	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LUM42_05545	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LUM42_05555	COG1737	Transcriptional regulator
LUM42_05560	COG0076	glutamate decarboxylase activity
LUM42_05570	COG2431	L-lysine efflux transmembrane transporter activity
LUM42_05580	COG3070	regulator of competence-specific genes
LUM42_05595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_05595	COG4191	Histidine kinase
LUM42_05605	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LUM42_05610	COG1053	succinate dehydrogenase
LUM42_05625	COG3940	Belongs to the glycosyl hydrolase 43 family
LUM42_05630	COG2211	Major facilitator Superfamily
LUM42_05635	COG1032	radical SAM domain protein
LUM42_05640	COG0488	(ABC) transporter
LUM42_05650	COG0346	lactoylglutathione lyase activity
LUM42_05670	COG0583	DNA-binding transcription factor activity
LUM42_05680	COG0840	transmembrane signaling receptor activity
LUM42_05685	COG2771	luxR family
LUM42_05685	COG2200	EAL domain
LUM42_05700	COG0612	Peptidase, M16
LUM42_05715	COG0583	DNA-binding transcription factor activity
LUM42_05750	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LUM42_05760	COG1815	bacterial-type flagellum-dependent cell motility
LUM42_05765	COG1558	bacterial-type flagellum-dependent cell motility
LUM42_05770	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LUM42_05775	COG1749	Flagellar hook protein flgE
LUM42_05785	COG4786	Flagellar basal body rod
LUM42_05790	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LUM42_05795	COG1706	bacterial-type flagellum-dependent cell motility
LUM42_05820	COG1677	Flagellar hook-basal body complex protein FliE
LUM42_05830	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LUM42_05860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_05865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_05870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_05875	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LUM42_05905	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LUM42_05910	COG1360	Flagellar Motor Protein
LUM42_05920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LUM42_05935	COG2350	Protein conserved in bacteria
LUM42_05950	COG1301	dicarboxylic acid transport
LUM42_05955	COG0159	tryptophan synthase activity
LUM42_05960	COG0133	tryptophan synthase activity
LUM42_05965	COG0135	phosphoribosylanthranilate isomerase activity
LUM42_05965	COG0134	indole-3-glycerol-phosphate synthase activity
LUM42_05970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LUM42_05975	COG0512	Glutamine amidotransferase of anthranilate synthase
LUM42_05980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LUM42_05990	COG0613	PHP domain protein
LUM42_05995	COG0837	glucose binding
LUM42_05995	COG1737	Transcriptional regulator
LUM42_06005	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LUM42_06015	COG4145	pantothenate transmembrane transporter activity
LUM42_06020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_06025	COG0800	Aldolase
LUM42_06035	COG0009	L-threonylcarbamoyladenylate synthase
LUM42_06040	COG1187	pseudouridine synthase activity
LUM42_06050	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LUM42_06055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LUM42_06060	COG4988	ABC transporter
LUM42_06065	COG0492	ferredoxin-NADP+ reductase activity
LUM42_06085	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LUM42_06095	COG2949	membrane
LUM42_06120	COG0583	DNA-binding transcription factor activity
LUM42_06130	COG0281	malic enzyme
LUM42_06135	COG1643	Atp-dependent helicase
LUM42_06150	COG0583	DNA-binding transcription factor activity
LUM42_06165	COG1757	Na H antiporter
LUM42_06170	COG0174	glutamine synthetase
LUM42_06175	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LUM42_06180	COG1396	sequence-specific DNA binding
LUM42_06180	COG1917	Cupin 2, conserved barrel domain protein
LUM42_06185	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_06190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUM42_06200	COG2957	Belongs to the agmatine deiminase family
LUM42_06210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUM42_06215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LUM42_06235	COG2885	chlorophyll binding
LUM42_06250	COG0247	lactate metabolic process
LUM42_06250	COG0277	FAD linked oxidase domain protein
LUM42_06270	COG2986	histidine ammonia-lyase
LUM42_06280	COG0010	Belongs to the arginase family
LUM42_06285	COG1228	amidohydrolase
LUM42_06300	COG3099	Belongs to the UPF0263 family
LUM42_06305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LUM42_06315	COG0417	DNA replication proofreading
LUM42_06320	COG2197	response regulator
LUM42_06325	COG0322	excinuclease ABC activity
LUM42_06355	COG2133	pyrroloquinoline quinone binding
LUM42_06375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LUM42_06380	COG0072	phenylalanine-tRNA ligase activity
LUM42_06380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LUM42_06385	COG0776	regulation of translation
LUM42_06395	COG0500	methyltransferase
LUM42_06425	COG5001	Diguanylate cyclase
LUM42_06430	COG0295	cytidine deaminase activity
LUM42_06435	COG1346	cytolysis
LUM42_06440	COG1380	Effector of murein hydrolase LrgA
LUM42_06445	COG2925	Exonuclease
LUM42_06470	COG1823	symporter activity
LUM42_06480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LUM42_06485	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LUM42_06490	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LUM42_06505	COG2988	succinylglutamate desuccinylase activity
LUM42_06510	COG4139	cobalamin transport
LUM42_06515	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
LUM42_06585	COG4964	Belongs to the GSP D family
LUM42_06630	COG1609	Transcriptional regulator
LUM42_06640	COG2182	Extracellular solute-binding protein
LUM42_06645	COG1175	transmembrane transport
LUM42_06650	COG3833	ABC-type maltose transport systems, permease component
LUM42_06660	COG1874	Beta-galactosidase
LUM42_06675	COG0110	maltose O-acetyltransferase activity
LUM42_06700	COG0583	DNA-binding transcription factor activity
LUM42_06710	COG1451	nucleotide metabolic process
LUM42_06725	COG3063	Type IV pilus biogenesis stability protein PilW
LUM42_06730	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LUM42_06750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_06765	COG3290	protein histidine kinase activity
LUM42_06770	COG4565	transcriptional regulatory protein
LUM42_06780	COG0835	chemotaxis
LUM42_06780	COG0784	Response regulator, receiver
LUM42_06790	COG1921	L-seryl-tRNASec selenium transferase activity
LUM42_06800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LUM42_06805	COG0651	ATP synthesis coupled electron transport
LUM42_06810	COG0650	Formate hydrogenlyase subunit 4
LUM42_06815	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LUM42_06815	COG3261	NADH dehydrogenase
LUM42_06820	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LUM42_06825	COG3260	NADH ubiquinone oxidoreductase 20
LUM42_06835	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LUM42_06840	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LUM42_06850	COG3604	Transcriptional regulator
LUM42_06855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LUM42_06865	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LUM42_06870	COG0298	carbon dioxide binding
LUM42_06880	COG0309	Hydrogenase expression formation protein (HypE)
LUM42_06885	COG0375	protein maturation
LUM42_06890	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LUM42_06895	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LUM42_06900	COG2897	thiosulfate sulfurtransferase activity
LUM42_06950	COG0668	transmembrane transport
LUM42_06970	COG0745	RESPONSE REGULATOR receiver
LUM42_06975	COG5002	protein histidine kinase activity
LUM42_07000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LUM42_07010	COG3391	amine dehydrogenase activity
LUM42_07015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LUM42_07020	COG1254	Belongs to the acylphosphatase family
LUM42_07025	COG2920	part of a sulfur-relay system
LUM42_07030	COG0670	Belongs to the BI1 family
LUM42_07035	COG1126	abc transporter atp-binding protein
LUM42_07040	COG0765	amino acid transport
LUM42_07045	COG4597	amino acid ABC transporter
LUM42_07050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_07060	COG0561	phosphatase activity
LUM42_07065	COG0602	queuosine metabolic process
LUM42_07070	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LUM42_07075	COG3005	denitrification pathway
LUM42_07080	COG0243	molybdopterin cofactor binding
LUM42_07085	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LUM42_07090	COG0657	acetylesterase activity
LUM42_07095	COG2999	glutathione oxidoreductase activity
LUM42_07125	COG0443	Heat shock 70 kDa protein
LUM42_07140	COG3706	GGDEF domain
LUM42_07170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LUM42_07175	COG1643	Atp-dependent helicase
LUM42_07210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LUM42_07240	COG4638	Rieske (2fe-2S)
LUM42_07245	COG0583	DNA-binding transcription factor activity
LUM42_07250	COG1414	Transcriptional regulator
LUM42_07270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_07275	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_07280	COG1120	ATPase activity
LUM42_07285	COG0583	DNA-binding transcription factor activity
LUM42_07290	COG4774	siderophore transport
LUM42_07295	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LUM42_07305	COG3501	Rhs element vgr protein
LUM42_07330	COG1115	amino acid carrier protein
LUM42_07345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUM42_07350	COG1666	GTP binding
LUM42_07355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LUM42_07375	COG2996	Protein conserved in bacteria
LUM42_07385	COG3008	intermembrane lipid transfer
LUM42_07390	COG2995	paraquat-inducible protein a
LUM42_07395	COG1132	(ABC) transporter
LUM42_07400	COG1956	GAF domain-containing protein
LUM42_07405	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
LUM42_07425	COG0308	aminopeptidase N
LUM42_07435	COG2902	Dehydrogenase
LUM42_07440	COG0167	dihydroorotate dehydrogenase activity
LUM42_07450	COG0116	Belongs to the methyltransferase superfamily
LUM42_07450	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LUM42_07460	COG0488	(ABC) transporter
LUM42_07475	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LUM42_07480	COG1067	ATP-dependent peptidase activity
LUM42_07485	COG3120	sequence-specific DNA binding
LUM42_07515	COG1450	Type ii and iii secretion system protein
LUM42_07685	COG2205	protein histidine kinase activity
LUM42_07685	COG0784	Response regulator, receiver
LUM42_07700	COG3278	Belongs to the heme-copper respiratory oxidase family
LUM42_07715	COG2010	Cytochrome c
LUM42_07740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUM42_07745	COG0589	response to stress
LUM42_07770	COG3842	ATPase activity
LUM42_07780	COG1177	transmembrane transport
LUM42_07790	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LUM42_07795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LUM42_07800	COG0004	ammonium transporteR
LUM42_07815	COG0437	4 iron, 4 sulfur cluster binding
LUM42_07830	COG3381	protein complex oligomerization
LUM42_07850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LUM42_07865	COG3852	Histidine kinase
LUM42_07870	COG2204	response regulator
LUM42_07880	COG4662	Binding-protein-dependent transport system inner membrane component
LUM42_07885	COG3842	ATPase activity
LUM42_07890	COG0746	molybdenum cofactor guanylyltransferase activity
LUM42_07895	COG0303	'Molybdopterin
LUM42_07905	COG1940	carbohydrate kinase activity
LUM42_07910	COG3148	PFAM DTW domain containing protein
LUM42_07925	COG0791	NLP P60 protein
LUM42_07935	COG3001	Fructosamine kinase
LUM42_07945	COG0307	riboflavin synthase, alpha
LUM42_07960	COG1793	dna ligase
LUM42_07965	COG4667	esterase of the alpha-beta hydrolase superfamily
LUM42_07985	COG0848	biopolymer transport protein
LUM42_07990	COG0811	peptide transport
LUM42_07995	COG0811	peptide transport
LUM42_08005	COG3040	lipid binding
LUM42_08010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUM42_08015	COG0039	L-malate dehydrogenase activity
LUM42_08030	COG0395	ABC-type sugar transport system, permease component
LUM42_08035	COG3842	ATPase activity
LUM42_08040	COG1349	DNA-binding transcription factor activity
LUM42_08050	COG2731	YhcH YjgK YiaL family protein
LUM42_08070	COG0625	glutathione transferase activity
LUM42_08080	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LUM42_08090	COG2200	EAL domain
LUM42_08095	COG2195	Cleaves the N-terminal amino acid of tripeptides
LUM42_08115	COG2814	Major facilitator Superfamily
LUM42_08120	COG1566	PFAM secretion protein HlyD family protein
LUM42_08140	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LUM42_08145	COG0372	Belongs to the citrate synthase family
LUM42_08150	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LUM42_08160	COG2169	Transcriptional regulator
LUM42_08160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LUM42_08195	COG1129	ABC transporter
LUM42_08205	COG3250	beta-galactosidase activity
LUM42_08215	COG2991	Protein conserved in bacteria
LUM42_08220	COG0778	Nitroreductase
LUM42_08225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LUM42_08240	COG4191	Histidine kinase
LUM42_08240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_08245	COG0471	metal ion transport
LUM42_08265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUM42_08280	COG3106	COG3106 Predicted ATPase
LUM42_08295	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LUM42_08300	COG2205	protein histidine kinase activity
LUM42_08300	COG0784	Response regulator, receiver
LUM42_08310	COG0494	nUDIX hydrolase
LUM42_08315	COG0814	amino acid
LUM42_08320	COG1760	l-serine dehydratase
LUM42_08325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_08330	COG1136	(ABC) transporter
LUM42_08330	COG0577	efflux transmembrane transporter activity
LUM42_08350	COG0720	synthase
LUM42_08360	COG0017	Asparaginyl-tRNA synthetase
LUM42_08375	COG1448	Aminotransferase
LUM42_08390	COG2176	DNA-directed DNA polymerase activity
LUM42_08395	COG0840	transmembrane signaling receptor activity
LUM42_08400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LUM42_08405	COG1846	Transcriptional regulator
LUM42_08430	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LUM42_08445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUM42_08450	COG3108	Peptidase M15
LUM42_08455	COG2989	Protein conserved in bacteria
LUM42_08480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LUM42_08495	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LUM42_08500	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LUM42_08530	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LUM42_08535	COG3265	gluconokinase activity
LUM42_08550	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LUM42_08595	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LUM42_08610	COG4181	ATPase activity
LUM42_08615	COG0534	Mate efflux family protein
LUM42_08620	COG0702	epimerase
LUM42_08630	COG2814	Major facilitator Superfamily
LUM42_08640	COG1061	Type III restriction enzyme res subunit
LUM42_08655	COG0642	Histidine kinase
LUM42_08660	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LUM42_08690	COG0679	Auxin Efflux Carrier
LUM42_08705	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LUM42_08720	COG3153	acetyltransferase
LUM42_08730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LUM42_08735	COG3069	C4-dicarboxylate transmembrane transporter activity
LUM42_08750	COG1737	Transcriptional regulator
LUM42_08765	COG1278	Cold shock
LUM42_08775	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LUM42_08785	COG0814	amino acid
LUM42_08795	COG1131	(ABC) transporter
LUM42_08800	COG0842	Transport permease protein
LUM42_08810	COG3313	Fe-S protein
LUM42_08820	COG4134	Bacterial extracellular solute-binding protein
LUM42_08825	COG4135	transport system, permease component
LUM42_08830	COG4136	ATPase activity
LUM42_08835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LUM42_08850	COG0564	pseudouridine synthase activity
LUM42_08860	COG0733	neurotransmitter:sodium symporter activity
LUM42_08870	COG0626	cystathionine gamma-synthase activity
LUM42_08875	COG2818	Glycosylase
LUM42_08890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_08905	COG1842	Phage shock protein A
LUM42_08910	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LUM42_08920	COG4168	peptide transport system, permease
LUM42_08925	COG4171	peptide transport system, permease
LUM42_08935	COG4172	Belongs to the ABC transporter superfamily
LUM42_08950	COG1227	inorganic diphosphatase activity
LUM42_08970	COG0243	molybdopterin cofactor binding
LUM42_08975	COG3005	denitrification pathway
LUM42_08980	COG4459	periplasmic nitrate reductase
LUM42_08985	COG0390	transport system, permease component
LUM42_08990	COG2116	formate transmembrane transporter activity
LUM42_09005	COG0583	DNA-binding transcription factor activity
LUM42_09010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LUM42_09015	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LUM42_09020	COG1435	thymidine kinase activity
LUM42_09030	COG1801	Protein of unknown function DUF72
LUM42_09035	COG4106	trans-aconitate 2-methyltransferase activity
LUM42_09040	COG0500	methyltransferase
LUM42_09045	COG4067	protein conserved in archaea
LUM42_09045	COG0189	ligase activity
LUM42_09065	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LUM42_09070	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LUM42_09075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LUM42_09080	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LUM42_09085	COG0745	RESPONSE REGULATOR receiver
LUM42_09090	COG3381	protein complex oligomerization
LUM42_09095	COG1609	Transcriptional regulator
LUM42_09100	COG3070	regulator of competence-specific genes
LUM42_09120	COG0297	glycogen (starch) synthase activity
LUM42_09125	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LUM42_09135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LUM42_09155	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LUM42_09160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LUM42_09165	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LUM42_09170	COG0542	response to heat
LUM42_09175	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LUM42_09180	COG1278	Cold shock
LUM42_09190	COG2223	nitrite transmembrane transporter activity
LUM42_09195	COG1695	Transcriptional regulator
LUM42_09205	COG1187	pseudouridine synthase activity
LUM42_09210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LUM42_09210	COG0140	phosphoribosyl-ATP diphosphatase activity
LUM42_09220	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LUM42_09225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LUM42_09230	COG0131	Imidazoleglycerol-phosphate dehydratase
LUM42_09230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LUM42_09235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LUM42_09240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LUM42_09245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LUM42_09250	COG2204	response regulator
LUM42_09255	COG1757	Na H antiporter
LUM42_09260	COG2916	Histone family protein nucleoid-structuring protein H-NS
LUM42_09265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_09270	COG0482	sulfurtransferase activity
LUM42_09275	COG2915	High frequency lysogenization protein hflD homolog
LUM42_09280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LUM42_09300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LUM42_09315	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_09325	COG0501	Belongs to the peptidase M48B family
LUM42_09335	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LUM42_09340	COG2226	methyltransferase
LUM42_09350	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LUM42_09355	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LUM42_09365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LUM42_09365	COG2146	nitrite reductase [NAD(P)H] activity
LUM42_09370	COG1116	anion transmembrane transporter activity
LUM42_09375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUM42_09380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUM42_09380	COG1116	anion transmembrane transporter activity
LUM42_09395	COG1648	precorrin-2 dehydrogenase activity
LUM42_09395	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LUM42_09400	COG0243	molybdopterin cofactor binding
LUM42_09410	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LUM42_09415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LUM42_09420	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LUM42_09425	COG0653	protein targeting
LUM42_09430	COG2165	general secretion pathway protein
LUM42_09440	COG3706	GGDEF domain
LUM42_09450	COG4120	Belongs to the binding-protein-dependent transport system permease family
LUM42_09460	COG3092	negative regulation of chromosome organization
LUM42_09465	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LUM42_09470	COG0280	phosphate acetyltransferase
LUM42_09470	COG0857	belongs to the CobB CobQ family
LUM42_09475	COG3174	membrane
LUM42_09480	COG0435	Glutathione S-transferase
LUM42_09495	COG0444	Belongs to the ABC transporter superfamily
LUM42_09500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUM42_09505	COG0601	transmembrane transport
LUM42_09540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUM42_09545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LUM42_09565	COG1216	Glycosyl transferase, family 2
LUM42_09570	COG2986	histidine ammonia-lyase
LUM42_09595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LUM42_09605	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_09625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_09635	COG2203	Gaf domain
LUM42_09635	COG3706	GGDEF domain
LUM42_09635	COG4251	negative regulation of phosphorylation
LUM42_09635	COG5001	Diguanylate cyclase
LUM42_09640	COG1621	beta-fructofuranosidase activity
LUM42_09650	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_09650	COG1263	PTS System
LUM42_09660	COG0745	RESPONSE REGULATOR receiver
LUM42_09670	COG2207	Transcriptional regulator
LUM42_09670	COG3708	Transcriptional regulator
LUM42_09675	COG2814	Major facilitator Superfamily
LUM42_09680	COG1566	PFAM secretion protein HlyD family protein
LUM42_09685	COG1538	Outer membrane efflux protein
LUM42_09695	COG0747	negative chemotaxis
LUM42_09700	COG0601	transmembrane transport
LUM42_09705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUM42_09710	COG4172	Belongs to the ABC transporter superfamily
LUM42_09720	COG1741	Belongs to the pirin family
LUM42_09725	COG2723	6-phospho-beta-galactosidase activity
LUM42_09730	COG1609	Transcriptional regulator
LUM42_09740	COG1120	ATPase activity
LUM42_09745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUM42_09755	COG1629	transport
LUM42_09755	COG4774	siderophore transport
LUM42_09760	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_09765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_09770	COG4592	Periplasmic binding protein
LUM42_09785	COG3433	isochorismatase activity
LUM42_09785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LUM42_09785	COG2226	methyltransferase
LUM42_09790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LUM42_09795	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_09800	COG1169	isochorismate synthase
LUM42_09805	COG1021	2,3-dihydroxybenzoate-AMP ligase
LUM42_09825	COG2249	NAD(P)H dehydrogenase (quinone) activity
LUM42_09840	COG3275	phosphorelay sensor kinase activity
LUM42_09845	COG3279	Response regulator of the LytR AlgR family
LUM42_09850	COG2223	nitrite transmembrane transporter activity
LUM42_09875	COG1294	oxidase, subunit
LUM42_09880	COG1271	oxidase subunit
LUM42_09885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_09920	COG4566	intracellular signal transduction
LUM42_09925	COG2194	sulfuric ester hydrolase activity
LUM42_09930	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LUM42_09935	COG1368	sulfuric ester hydrolase activity
LUM42_09940	COG0513	Belongs to the DEAD box helicase family
LUM42_09960	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LUM42_09965	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LUM42_09985	COG2207	Transcriptional regulator
LUM42_09990	COG1881	PFAM PEBP family protein
LUM42_10010	COG2723	6-phospho-beta-galactosidase activity
LUM42_10015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_10015	COG2190	(PTS) system
LUM42_10015	COG1263	PTS System
LUM42_10020	COG3711	transcriptional antiterminator
LUM42_10025	COG0679	Auxin Efflux Carrier
LUM42_10030	COG0583	DNA-binding transcription factor activity
LUM42_10040	COG5001	Diguanylate cyclase
LUM42_10040	COG5002	protein histidine kinase activity
LUM42_10055	COG3126	Type III secretion system lipoprotein chaperone (YscW)
LUM42_10060	COG1946	Acyl-CoA thioesterase
LUM42_10065	COG1522	sequence-specific DNA binding
LUM42_10110	COG3047	cAMP biosynthetic process
LUM42_10110	COG2885	chlorophyll binding
LUM42_10140	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LUM42_10155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_10160	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LUM42_10180	COG1580	Controls the rotational direction of flagella during chemotaxis
LUM42_10190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LUM42_10195	COG1360	Flagellar Motor Protein
LUM42_10205	COG3015	lipoprotein NlpE involved in copper resistance
LUM42_10250	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
LUM42_10280	COG1256	bacterial-type flagellum assembly
LUM42_10280	COG4786	Flagellar basal body rod
LUM42_10290	COG1706	bacterial-type flagellum-dependent cell motility
LUM42_10295	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LUM42_10300	COG4786	Flagellar basal body rod
LUM42_10310	COG1749	Flagellar hook protein flgE
LUM42_10315	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
LUM42_10320	COG1558	bacterial-type flagellum-dependent cell motility
LUM42_10325	COG1815	bacterial-type flagellum-dependent cell motility
LUM42_10345	COG0741	lytic transglycosylase activity
LUM42_10345	COG1388	LysM domain
LUM42_10350	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LUM42_10370	COG0477	Major facilitator Superfamily
LUM42_10375	COG2855	membrane
LUM42_10395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LUM42_10405	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LUM42_10415	COG0436	Aminotransferase
LUM42_10420	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LUM42_10425	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LUM42_10445	COG0616	signal peptide processing
LUM42_10450	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_10465	COG0587	DNA-directed DNA polymerase activity
LUM42_10470	COG0835	chemotaxis
LUM42_10470	COG0784	Response regulator, receiver
LUM42_10475	COG1940	carbohydrate kinase activity
LUM42_10480	COG0469	pyruvate kinase activity
LUM42_10485	COG4667	esterase of the alpha-beta hydrolase superfamily
LUM42_10500	COG0733	neurotransmitter:sodium symporter activity
LUM42_10515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_10515	COG1263	PTS System
LUM42_10525	COG1263	PTS System
LUM42_10525	COG2190	(PTS) system
LUM42_10525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LUM42_10530	COG0084	hydrolase, TatD family'
LUM42_10535	COG0470	DNA polymerase III
LUM42_10540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LUM42_10545	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LUM42_10550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LUM42_10555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LUM42_10575	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUM42_10580	COG0416	fatty acid biosynthetic process
LUM42_10585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LUM42_10590	COG1399	metal-binding, possibly nucleic acid-binding protein
LUM42_10595	COG0424	maF-like protein
LUM42_10600	COG0564	pseudouridine synthase activity
LUM42_10605	COG1530	ribonuclease E activity
LUM42_10615	COG0659	secondary active sulfate transmembrane transporter activity
LUM42_10625	COG1454	alcohol dehydrogenase
LUM42_10625	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_10630	COG2095	MarC family integral membrane protein
LUM42_10635	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LUM42_10640	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LUM42_10645	COG1757	Na H antiporter
LUM42_10655	COG3081	Nucleoid-associated protein
LUM42_10660	COG3082	Protein of unknown function (DUF1414)
LUM42_10665	COG3083	sulfuric ester hydrolase activity
LUM42_10680	COG2814	Major facilitator Superfamily
LUM42_10700	COG1448	Aminotransferase
LUM42_10710	COG0123	including yeast histone deacetylase and acetoin utilization protein
LUM42_10725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LUM42_10765	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUM42_10770	COG2159	amidohydrolase
LUM42_10775	COG0583	DNA-binding transcription factor activity
LUM42_10790	COG0667	Aldo Keto reductase
LUM42_10795	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LUM42_10815	COG3384	dioxygenase
LUM42_10825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LUM42_10830	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LUM42_10850	COG2853	Lipoprotein
LUM42_10865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LUM42_10870	COG1138	Cytochrome C-type biogenesis protein
LUM42_10875	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LUM42_10880	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LUM42_10885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LUM42_10890	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LUM42_10895	COG4133	protoheme IX ABC transporter activity
LUM42_10905	COG0835	chemotaxis
LUM42_10915	COG1192	Involved in chromosome partitioning
LUM42_10920	COG2201	protein-glutamate methylesterase activity
LUM42_10925	COG0784	Response regulator, receiver
LUM42_10925	COG2198	Histidine kinase
LUM42_10925	COG0643	Histidine kinase
LUM42_10930	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LUM42_10960	COG2062	phosphohistidine phosphatase, SixA
LUM42_10970	COG3102	Protein conserved in bacteria
LUM42_10995	COG1918	ferrous iron import across plasma membrane
LUM42_11000	COG2207	Transcriptional regulator
LUM42_11005	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LUM42_11010	COG1121	(ABC) transporter
LUM42_11015	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LUM42_11030	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUM42_11035	COG0567	Dehydrogenase, E1 component
LUM42_11045	COG1053	succinate dehydrogenase
LUM42_11050	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LUM42_11065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LUM42_11075	COG0033	Phosphoglucomutase
LUM42_11080	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LUM42_11085	COG0596	Alpha beta hydrolase
LUM42_11100	COG1346	cytolysis
LUM42_11105	COG1380	Effector of murein hydrolase LrgA
LUM42_11110	COG0583	DNA-binding transcription factor activity
LUM42_11120	COG0735	belongs to the Fur family
LUM42_11125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LUM42_11130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUM42_11135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LUM42_11140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUM42_11140	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LUM42_11155	COG3101	peptidyl-lysine hydroxylation
LUM42_11160	COG2860	membrane
LUM42_11165	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LUM42_11170	COG2890	protein-(glutamine-N5) methyltransferase activity
LUM42_11175	COG2840	Smr protein MutS2
LUM42_11190	COG1987	bacterial-type flagellum assembly
LUM42_11240	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LUM42_11250	COG1677	Flagellar hook-basal body complex protein FliE
LUM42_11270	COG1516	flagellar protein fliS
LUM42_11280	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LUM42_11285	COG1334	flagellar protein FlaG
LUM42_11290	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_11305	COG2837	iron assimilation
LUM42_11325	COG0517	IMP dehydrogenase activity
LUM42_11325	COG0516	GMP reductase activity
LUM42_11340	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LUM42_11345	COG1085	galactose-1-phosphate uridylyltransferase
LUM42_11350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LUM42_11360	COG1393	Belongs to the ArsC family
LUM42_11370	COG1876	peptidase activity
LUM42_11380	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LUM42_11390	COG2716	regulation of RNA biosynthetic process
LUM42_11420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LUM42_11480	COG4783	chaperone-mediated protein folding
LUM42_11485	COG1393	Belongs to the ArsC family
LUM42_11505	COG2233	PERMEase
LUM42_11510	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LUM42_11515	COG0737	Belongs to the 5'-nucleotidase family
LUM42_11520	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LUM42_11525	COG2912	Transglutaminase-like superfamily
LUM42_11535	COG2890	protein-(glutamine-N5) methyltransferase activity
LUM42_11540	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LUM42_11545	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LUM42_11550	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LUM42_11555	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LUM42_11560	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LUM42_11565	COG0193	aminoacyl-tRNA hydrolase activity
LUM42_11665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_11670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LUM42_11680	COG1705	Flagellar rod assembly protein muramidase FlgJ
LUM42_11680	COG3951	Flagellar rod assembly protein muramidase FlgJ
LUM42_11685	COG1706	bacterial-type flagellum-dependent cell motility
LUM42_11690	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LUM42_11700	COG4787	bacterial-type flagellum-dependent cell motility
LUM42_11720	COG1815	bacterial-type flagellum-dependent cell motility
LUM42_11725	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LUM42_11730	COG0784	Response regulator, receiver
LUM42_11730	COG0835	chemotaxis
LUM42_11740	COG2747	anti-sigma28 factor FlgM
LUM42_11780	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LUM42_11785	COG2217	Heavy metal translocating P-type atpase
LUM42_11785	COG2608	mercury ion transmembrane transporter activity
LUM42_11820	COG2840	Smr protein MutS2
LUM42_11825	COG1187	pseudouridine synthase activity
LUM42_11830	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LUM42_11835	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LUM42_11840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LUM42_11845	COG0121	glutamine amidotransferase
LUM42_11850	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LUM42_11855	COG1960	acyl-CoA dehydrogenase activity
LUM42_11865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LUM42_11870	COG0328	RNA-DNA hybrid ribonuclease activity
LUM42_11875	COG2226	methyltransferase
LUM42_11880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LUM42_11885	COG1388	LysM domain
LUM42_11885	COG0741	lytic transglycosylase activity
LUM42_11895	COG3021	interspecies interaction between organisms
LUM42_11900	COG0347	Belongs to the P(II) protein family
LUM42_11910	COG0037	tRNA processing
LUM42_11915	COG0825	malonyl-CoA metabolic process
LUM42_11920	COG0587	DNA-directed DNA polymerase activity
LUM42_11925	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LUM42_11940	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LUM42_11945	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LUM42_11950	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LUM42_11960	COG0750	zinc metalloprotease
LUM42_11965	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LUM42_11970	COG0575	Belongs to the CDS family
LUM42_11975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LUM42_11980	COG0233	cytoplasmic translational termination
LUM42_11990	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LUM42_11995	COG0052	Belongs to the universal ribosomal protein uS2 family
LUM42_12000	COG0024	Methionine aminopeptidase
LUM42_12005	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LUM42_12015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LUM42_12020	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LUM42_12025	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LUM42_12030	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LUM42_12045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LUM42_12045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LUM42_12050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LUM42_12055	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LUM42_12070	COG1073	alpha beta
LUM42_12075	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LUM42_12080	COG2252	PERMEase
LUM42_12085	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LUM42_12095	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LUM42_12105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUM42_12110	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_12115	COG2195	Cleaves the N-terminal amino acid of tripeptides
LUM42_12120	COG0189	ligase activity
LUM42_12120	COG4067	protein conserved in archaea
LUM42_12125	COG0189	ligase activity
LUM42_12135	COG0733	neurotransmitter:sodium symporter activity
LUM42_12140	COG3706	GGDEF domain
LUM42_12140	COG4251	negative regulation of phosphorylation
LUM42_12140	COG5001	Diguanylate cyclase
LUM42_12140	COG2203	Gaf domain
LUM42_12150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LUM42_12165	COG1477	protein flavinylation
LUM42_12170	COG2871	sodium ion transport
LUM42_12175	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LUM42_12180	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LUM42_12190	COG1805	sodium ion transport
LUM42_12195	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LUM42_12200	COG0271	Belongs to the BolA IbaG family
LUM42_12275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUM42_12285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUM42_12290	COG0590	tRNA wobble adenosine to inosine editing
LUM42_12300	COG0542	response to heat
LUM42_12310	COG0564	pseudouridine synthase activity
LUM42_12315	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LUM42_12320	COG0741	lytic transglycosylase activity
LUM42_12325	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LUM42_12330	COG0077	Prephenate dehydratase
LUM42_12330	COG1605	Chorismate mutase
LUM42_12335	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LUM42_12340	COG5001	Diguanylate cyclase
LUM42_12345	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LUM42_12350	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LUM42_12360	COG0488	(ABC) transporter
LUM42_12370	COG1605	Chorismate mutase
LUM42_12370	COG0287	Prephenate dehydrogenase
LUM42_12375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LUM42_12380	COG3275	phosphorelay sensor kinase activity
LUM42_12385	COG3279	Response regulator of the LytR AlgR family
LUM42_12395	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LUM42_12400	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LUM42_12415	COG1966	Carbon starvation protein
LUM42_12420	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LUM42_12425	COG1047	Peptidyl-prolyl cis-trans
LUM42_12430	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LUM42_12435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LUM42_12440	COG0196	riboflavin kinase activity
LUM42_12445	COG0728	peptidoglycan biosynthetic process
LUM42_12450	COG0268	Binds directly to 16S ribosomal RNA
LUM42_12455	COG0640	Transcriptional regulator
LUM42_12460	COG0583	DNA-binding transcription factor activity
LUM42_12465	COG1283	sodium-dependent phosphate transmembrane transporter activity
LUM42_12470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LUM42_12480	COG0730	response to heat
LUM42_12490	COG0494	nUDIX hydrolase
LUM42_12505	COG0667	Aldo Keto reductase
LUM42_12515	COG2204	response regulator
LUM42_12520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LUM42_12535	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LUM42_12540	COG0513	Belongs to the DEAD box helicase family
LUM42_12630	COG1279	arginine transmembrane transporter activity
LUM42_12655	COG4533	DNA binding
LUM42_12675	COG2003	Belongs to the UPF0758 family
LUM42_12700	COG0714	Associated with various cellular activities
LUM42_12720	COG0629	single-stranded DNA binding
LUM42_12735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LUM42_12755	COG3706	GGDEF domain
LUM42_12790	COG0681	Belongs to the peptidase S26 family
LUM42_12900	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LUM42_12910	COG0732	type I restriction modification DNA specificity domain
LUM42_12915	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LUM42_12935	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LUM42_12975	COG0557	exoribonuclease II activity
LUM42_12980	COG1278	Cold shock
LUM42_12995	COG3550	peptidyl-serine autophosphorylation
LUM42_13000	COG3620	sequence-specific DNA binding
LUM42_13020	COG3153	acetyltransferase
LUM42_13025	COG3154	lipid carrier protein
LUM42_13035	COG0826	peptidase U32
LUM42_13040	COG0826	peptidase U32
LUM42_13045	COG0534	Mate efflux family protein
LUM42_13065	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LUM42_13075	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LUM42_13080	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LUM42_13085	COG0195	Participates in both transcription termination and antitermination
LUM42_13090	COG0779	Required for maturation of 30S ribosomal subunits
LUM42_13105	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LUM42_13110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUM42_13115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LUM42_13120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LUM42_13125	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LUM42_13130	COG1534	Rna-binding protein
LUM42_13135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUM42_13140	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LUM42_13145	COG2027	D-alanyl-D-alanine carboxypeptidase
LUM42_13150	COG2239	Acts as a magnesium transporter
LUM42_13160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LUM42_13165	COG0739	heme binding
LUM42_13180	COG0316	Belongs to the HesB IscA family
LUM42_13185	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LUM42_13190	COG0628	permease
LUM42_13195	COG2813	Specifically methylates the guanine in position
LUM42_13200	COG2205	protein histidine kinase activity
LUM42_13200	COG0784	Response regulator, receiver
LUM42_13205	COG0747	negative chemotaxis
LUM42_13215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LUM42_13220	COG0444	Belongs to the ABC transporter superfamily
LUM42_13225	COG4608	Belongs to the ABC transporter superfamily
LUM42_13235	COG2971	BadF BadG BcrA BcrD
LUM42_13250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUM42_13255	COG3842	ATPase activity
LUM42_13265	COG1840	ABC-type Fe3 transport system, periplasmic component
LUM42_13270	COG0004	ammonium transporteR
LUM42_13275	COG0347	Belongs to the P(II) protein family
LUM42_13280	COG3112	Uncharacterised protein family (UPF0231)
LUM42_13285	COG1049	propionate catabolic process, 2-methylcitrate cycle
LUM42_13290	COG1752	Esterase of the alpha-beta hydrolase superfamily
LUM42_13295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUM42_13300	COG1643	Atp-dependent helicase
LUM42_13305	COG1489	DNA binding
LUM42_13310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LUM42_13315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LUM42_13325	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LUM42_13330	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LUM42_13335	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LUM42_13340	COG0842	Transport permease protein
LUM42_13345	COG1131	(ABC) transporter
LUM42_13350	COG0288	reversible hydration of carbon dioxide
LUM42_13365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LUM42_13370	COG0508	dehydrogenase complex catalyzes the overall conversion of
LUM42_13375	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LUM42_13380	COG2186	Transcriptional regulator
LUM42_13385	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LUM42_13390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LUM42_13395	COG4974	Belongs to the 'phage' integrase family
LUM42_13420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LUM42_13425	COG1459	type II secretion system
LUM42_13435	COG0237	dephospho-CoA kinase activity
LUM42_13440	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LUM42_13460	COG3150	esterase
LUM42_13470	COG3151	Protein conserved in bacteria
LUM42_13475	COG0494	nUDIX hydrolase
LUM42_13480	COG1538	Outer membrane efflux protein
LUM42_13485	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LUM42_13485	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LUM42_13490	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LUM42_13500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LUM42_13505	COG3025	triphosphatase activity
LUM42_13510	COG1392	Phosphate transport regulator
LUM42_13515	COG0306	phosphate transporter
LUM42_13520	COG4991	sh3 domain protein
LUM42_13530	COG3267	Type II secretory pathway component ExeA
LUM42_13530	COG3409	Peptidoglycan-binding domain 1 protein
LUM42_13535	COG0617	tRNA 3'-terminal CCA addition
LUM42_13540	COG0148	phosphopyruvate hydratase activity
LUM42_13545	COG0504	CTP synthase activity
LUM42_13550	COG3956	TIGRFAM MazG family protein
LUM42_13555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LUM42_13560	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LUM42_13575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LUM42_13580	COG1381	Involved in DNA repair and RecF pathway recombination
LUM42_13585	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LUM42_13600	COG0481	GTPase activity
LUM42_13605	COG3086	response to oxidative stress
LUM42_13620	COG1595	DNA-templated transcription, initiation
LUM42_13625	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LUM42_13635	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LUM42_13655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUM42_13660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LUM42_13665	COG3079	Belongs to the UPF0149 family
LUM42_13670	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LUM42_13680	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LUM42_13690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LUM42_13695	COG0440	acetolactate synthase activity
LUM42_13700	COG0028	Belongs to the TPP enzyme family
LUM42_13705	COG1022	Amp-dependent synthetase and ligase
LUM42_13710	COG0583	DNA-binding transcription factor activity
LUM42_13735	COG0473	3-isopropylmalate dehydrogenase activity
LUM42_13740	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LUM42_13745	COG0066	3-isopropylmalate dehydratase activity
LUM42_13790	COG3437	response regulator, receiver
LUM42_13815	COG3706	GGDEF domain
LUM42_13825	COG0795	lipopolysaccharide-transporting ATPase activity
LUM42_13830	COG0795	lipopolysaccharide-transporting ATPase activity
LUM42_13835	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LUM42_13845	COG0525	valine-tRNA ligase activity
LUM42_13850	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUM42_13855	COG0564	pseudouridine synthase activity
LUM42_13870	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LUM42_13875	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LUM42_13880	COG0540	Belongs to the ATCase OTCase family
LUM42_13885	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LUM42_13890	COG0251	oxidation-reduction process
LUM42_13895	COG0204	Acyl-transferase
LUM42_13905	COG5007	Belongs to the BolA IbaG family
LUM42_13910	COG3113	response to antibiotic
LUM42_13915	COG2854	intermembrane phospholipid transfer
LUM42_13920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LUM42_13925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LUM42_13930	COG1127	ABC transporter
LUM42_13940	COG0517	IMP dehydrogenase activity
LUM42_13940	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LUM42_13945	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LUM42_13955	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LUM42_13960	COG1137	ATPase activity
LUM42_13970	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LUM42_13975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_13980	COG1660	Displays ATPase and GTPase activities
LUM42_13985	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_13990	COG2239	Acts as a magnesium transporter
LUM42_13995	COG0312	modulator of DNA gyrase
LUM42_14000	COG3028	Belongs to the UPF0307 family
LUM42_14005	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LUM42_14010	COG1178	ABC-type Fe3 transport system permease component
LUM42_14015	COG4143	(ABC) transporter
LUM42_14020	COG0163	prenyltransferase activity
LUM42_14025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LUM42_14030	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LUM42_14035	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LUM42_14045	COG2105	PFAM AIG2 family protein
LUM42_14055	COG0729	surface antigen
LUM42_14060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUM42_14065	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LUM42_14080	COG1136	(ABC) transporter
LUM42_14080	COG0577	efflux transmembrane transporter activity
LUM42_14100	COG0529	Catalyzes the synthesis of activated sulfate
LUM42_14105	COG0471	metal ion transport
LUM42_14105	COG3273	potassium ion transport
LUM42_14110	COG2895	sulfate adenylyltransferase (ATP) activity
LUM42_14115	COG0175	sulfate reduction
LUM42_14120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LUM42_14120	COG1648	precorrin-2 dehydrogenase activity
LUM42_14125	COG0737	Belongs to the 5'-nucleotidase family
LUM42_14135	COG0513	Belongs to the DEAD box helicase family
LUM42_14140	COG2153	protein acetylation
LUM42_14150	COG3061	Opacity-associated protein A
LUM42_14155	COG0545	Peptidyl-prolyl cis-trans isomerase
LUM42_14165	COG0203	ribosomal protein L17
LUM42_14170	COG0202	RNA polymerase activity
LUM42_14175	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LUM42_14180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LUM42_14185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LUM42_14190	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LUM42_14195	COG0201	protein transport
LUM42_14200	COG0200	Binds to the 23S rRNA
LUM42_14205	COG1841	ribosomal large subunit assembly
LUM42_14215	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LUM42_14225	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LUM42_14230	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LUM42_14235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LUM42_14240	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LUM42_14245	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LUM42_14250	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LUM42_14255	COG0255	Belongs to the universal ribosomal protein uL29 family
LUM42_14260	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LUM42_14265	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LUM42_14270	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LUM42_14275	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LUM42_14280	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LUM42_14285	COG0089	rRNA binding
LUM42_14290	COG0088	Forms part of the polypeptide exit tunnel
LUM42_14295	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LUM42_14300	COG0051	transcription antitermination factor activity, RNA binding
LUM42_14305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LUM42_14310	COG0557	exoribonuclease II activity
LUM42_14315	COG3083	sulfuric ester hydrolase activity
LUM42_14320	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LUM42_14325	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LUM42_14335	COG1047	Peptidyl-prolyl cis-trans
LUM42_14340	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LUM42_14350	COG2249	NAD(P)H dehydrogenase (quinone) activity
LUM42_14355	COG0488	(ABC) transporter
LUM42_14365	COG0429	hydrolase of the alpha beta-hydrolase fold
LUM42_14375	COG3954	Phosphoribulokinase
LUM42_14390	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_14400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LUM42_14405	COG0512	Glutamine amidotransferase of anthranilate synthase
LUM42_14415	COG0180	Tryptophanyl-tRNA synthetase
LUM42_14425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LUM42_14430	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LUM42_14440	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LUM42_14475	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LUM42_14485	COG0678	peroxiredoxin activity
LUM42_14485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LUM42_14495	COG0165	Argininosuccinate lyase
LUM42_14495	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LUM42_14505	COG0137	argininosuccinate synthase activity
LUM42_14510	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LUM42_14515	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LUM42_14520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LUM42_14525	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LUM42_14535	COG1045	serine acetyltransferase
LUM42_14545	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LUM42_14550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUM42_14555	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LUM42_14560	COG1053	succinate dehydrogenase
LUM42_14565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LUM42_14570	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LUM42_14580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LUM42_14585	COG1509	lysine 2,3-aminomutase activity
LUM42_14590	COG1285	pathogenesis
LUM42_14600	COG1119	ATPase activity
LUM42_14605	COG0459	protein refolding
LUM42_14635	COG0149	triose-phosphate isomerase activity
LUM42_14640	COG0534	Mate efflux family protein
LUM42_14645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LUM42_14650	COG1575	Belongs to the MenA family. Type 1 subfamily
LUM42_14655	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LUM42_14660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LUM42_14670	COG1609	Transcriptional regulator
LUM42_14675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LUM42_14685	COG0281	malic enzyme
LUM42_14690	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LUM42_14695	COG0626	cystathionine gamma-synthase activity
LUM42_14700	COG0460	homoserine dehydrogenase
LUM42_14700	COG0527	aspartate kinase activity
LUM42_14705	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LUM42_14710	COG3074	FtsZ-dependent cytokinesis
LUM42_14715	COG1494	fructose-1,6-bisphosphatase
LUM42_14720	COG0205	6-phosphofructokinase activity
LUM42_14725	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LUM42_14735	COG0745	RESPONSE REGULATOR receiver
LUM42_14740	COG2205	protein histidine kinase activity
LUM42_14745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LUM42_14750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LUM42_14765	COG1027	Aspartate ammonia-lyase
LUM42_14770	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LUM42_14775	COG1288	antiporter activity
LUM42_14790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LUM42_14795	COG0540	Belongs to the ATCase OTCase family
LUM42_14800	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LUM42_14810	COG4232	protein-disulfide reductase activity
LUM42_14835	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LUM42_14840	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LUM42_14845	COG0194	GDP metabolic process
LUM42_14850	COG1758	RNA polymerase activity
LUM42_14855	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LUM42_14865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LUM42_14870	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LUM42_14875	COG2233	PERMEase
LUM42_14890	COG0800	Aldolase
LUM42_14895	COG2610	gluconate transmembrane transporter activity
LUM42_14900	COG3265	gluconokinase activity
LUM42_14905	COG0129	dihydroxy-acid dehydratase activity
LUM42_14910	COG1609	Transcriptional regulator
LUM42_14915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUM42_14925	COG2183	response to ionizing radiation
LUM42_14935	COG0596	Alpha beta hydrolase
LUM42_14940	COG1040	competence protein
LUM42_14950	COG0494	nUDIX hydrolase
LUM42_14955	COG1218	3'(2'),5'-bisphosphate nucleotidase
LUM42_14965	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LUM42_14970	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LUM42_14975	COG3156	type II secretion system protein K
LUM42_14980	COG4795	General secretion pathway protein
LUM42_14985	COG2165	general secretion pathway protein
LUM42_14990	COG2165	general secretion pathway protein
LUM42_14995	COG2165	general secretion pathway protein
LUM42_15000	COG1459	type II secretion system
LUM42_15005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LUM42_15015	COG3031	protein transport across the cell outer membrane
LUM42_15020	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LUM42_15030	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LUM42_15035	COG2982	Protein involved in outer membrane biogenesis
LUM42_15040	COG0456	acetyltransferase
LUM42_15045	COG1490	D-aminoacyl-tRNA deacylase activity
LUM42_15065	COG1217	gtp-binding protein TYPA
LUM42_15070	COG0174	glutamine synthetase
LUM42_15080	COG3852	Histidine kinase
LUM42_15085	COG2204	response regulator
LUM42_15090	COG5001	Diguanylate cyclase
LUM42_15090	COG3300	MHYT domain
LUM42_15095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LUM42_15145	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LUM42_15155	COG4206	TonB-dependent receptor
LUM42_15160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LUM42_15175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LUM42_15180	COG0534	Mate efflux family protein
LUM42_15190	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LUM42_15195	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LUM42_15200	COG2937	Belongs to the GPAT DAPAT family
LUM42_15205	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LUM42_15210	COG3161	chorismate lyase activity
LUM42_15215	COG1580	Controls the rotational direction of flagella during chemotaxis
LUM42_15220	COG0705	Rhomboid family
LUM42_15225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUM42_15230	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LUM42_15235	COG2177	Part of the ABC transporter FtsEX involved in
LUM42_15240	COG2884	Cell division ATP-binding protein ftsE
LUM42_15245	COG0552	protein localization to endoplasmic reticulum
LUM42_15250	COG0742	ribosomal rna small subunit methyltransferase
LUM42_15260	COG2095	MarC family integral membrane protein
LUM42_15290	COG0783	Belongs to the Dps family
LUM42_15305	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LUM42_15310	COG0640	Transcriptional regulator
LUM42_15315	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LUM42_15320	COG1280	lysine exporter protein (LysE YggA)
LUM42_15325	COG2267	carboxylic ester hydrolase activity
LUM42_15330	COG0561	phosphatase activity
LUM42_15345	COG3148	PFAM DTW domain containing protein
LUM42_15350	COG2199	diguanylate cyclase activity
LUM42_15350	COG2200	EAL domain
LUM42_15350	COG3287	FIST C domain
LUM42_15355	COG1011	Hydrolase
LUM42_15360	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LUM42_15370	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LUM42_15375	COG0019	diaminopimelate decarboxylase activity
LUM42_15385	COG1965	Belongs to the frataxin family
LUM42_15390	COG3072	Adenylate cyclase
LUM42_15405	COG2959	enzyme of heme biosynthesis
LUM42_15410	COG3071	HemY protein
LUM42_15415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LUM42_15445	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LUM42_15445	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LUM42_15460	COG0084	hydrolase, TatD family'
LUM42_15465	COG0805	protein transport
LUM42_15470	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LUM42_15475	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LUM42_15485	COG3165	ubiquinone biosynthetic process from chorismate
LUM42_15490	COG2226	methyltransferase
LUM42_15495	COG1322	Protein conserved in bacteria
LUM42_15520	COG2160	L-arabinose isomerase activity
LUM42_15530	COG1069	ribulokinase activity
LUM42_15535	COG1879	ABC-type sugar transport system periplasmic component
LUM42_15540	COG1129	ABC transporter
LUM42_15545	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUM42_15550	COG1879	ABC-type sugar transport system periplasmic component
LUM42_15555	COG1129	ABC transporter
LUM42_15560	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUM42_15565	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUM42_15570	COG2081	HI0933 family
LUM42_15580	COG1528	Iron-storage protein
LUM42_15585	COG0589	response to stress
LUM42_15605	COG5002	protein histidine kinase activity
LUM42_15605	COG5001	Diguanylate cyclase
LUM42_15610	COG1522	sequence-specific DNA binding
LUM42_15630	COG0006	proline dipeptidase activity
LUM42_15630	COG0006	proline dipeptidase activity
LUM42_15635	COG1309	transcriptional regulator
LUM42_15640	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_15645	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LUM42_15660	COG4175	Glycine betaine
LUM42_15665	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LUM42_15670	COG2022	thiamine diphosphate biosynthetic process
LUM42_15680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LUM42_15690	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LUM42_15695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LUM42_15700	COG2132	Multicopper oxidase
LUM42_15775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LUM42_15780	COG1739	Uncharacterized protein family UPF0029
LUM42_15790	COG0183	Belongs to the thiolase family
LUM42_15795	COG0583	DNA-binding transcription factor activity
LUM42_15800	COG2814	Major facilitator Superfamily
LUM42_15810	COG0765	amino acid transport
LUM42_15820	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LUM42_15825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LUM42_15830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LUM42_15835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LUM42_15840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LUM42_15845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LUM42_15860	COG3312	ion transport
LUM42_15865	COG1475	DNA binding
LUM42_15870	COG1192	Involved in chromosome partitioning
LUM42_15875	COG0357	Ribosomal RNA small subunit methyltransferase G
LUM42_15880	COG0445	tRNA wobble uridine modification
LUM42_15885	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LUM42_15895	COG0706	membrane insertase activity
LUM42_15910	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LUM42_15915	COG1126	abc transporter atp-binding protein
LUM42_15980	COG1660	Displays ATPase and GTPase activities
LUM42_16020	COG0616	signal peptide processing
LUM42_16125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LUM42_16190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LUM42_16250	COG3041	Addiction module toxin RelE StbE family
LUM42_16255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LUM42_16310	COG1192	Involved in chromosome partitioning
LUM42_16395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LUM42_16445	COG3328	transposase activity
LUM42_16495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LUM42_16520	COG5001	Diguanylate cyclase
LUM42_16555	COG0714	Associated with various cellular activities
LUM42_16565	COG0629	single-stranded DNA binding
LUM42_16610	COG0633	Ferredoxin
LUM42_16835	COG1396	sequence-specific DNA binding
LUM42_16875	COG3173	Aminoglycoside phosphotransferase
LUM42_16890	COG4644	lycopene metabolic process
LUM42_16980	COG4974	Belongs to the 'phage' integrase family
LUM42_17070	COG2909	trisaccharide binding
LUM42_17080	COG0109	protoheme IX farnesyltransferase activity
LUM42_17085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LUM42_17090	COG1845	cytochrome c oxidase, subunit III
LUM42_17095	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LUM42_17100	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LUM42_17115	COG2084	Dehydrogenase
LUM42_17130	COG0217	transcriptional regulatory protein
LUM42_17160	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LUM42_17165	COG1444	tRNA N-acetyltransferase activity
LUM42_17180	COG0643	Histidine kinase
LUM42_17180	COG2198	Histidine kinase
LUM42_17185	COG0835	chemotaxis
LUM42_17190	COG0835	chemotaxis
LUM42_17195	COG0840	transmembrane signaling receptor activity
LUM42_17200	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LUM42_17205	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LUM42_17210	COG2201	protein-glutamate methylesterase activity
LUM42_17225	COG0745	RESPONSE REGULATOR receiver
LUM42_17245	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LUM42_17280	COG0840	transmembrane signaling receptor activity
LUM42_17300	COG0513	Belongs to the DEAD box helicase family
LUM42_17310	COG0583	DNA-binding transcription factor activity
LUM42_17315	COG2226	methyltransferase
LUM42_17335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LUM42_17355	COG0724	RNA recognition motif
LUM42_17360	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LUM42_17365	COG1522	sequence-specific DNA binding
LUM42_17370	COG2610	gluconate transmembrane transporter activity
LUM42_17375	COG3622	Belongs to the hyi family
LUM42_17380	COG0235	Class ii aldolase
LUM42_17385	COG3395	kinase activity
LUM42_17390	COG2084	Dehydrogenase
LUM42_17395	COG1349	DNA-binding transcription factor activity
LUM42_17410	COG0583	DNA-binding transcription factor activity
LUM42_17415	COG2910	NAD(P)H-binding
LUM42_17430	COG1335	isochorismatase
LUM42_17435	COG2207	Transcriptional regulator
LUM42_17435	COG1609	Transcriptional regulator
LUM42_17450	COG2329	Antibiotic biosynthesis monooxygenase
LUM42_17455	COG3304	Inner membrane component domain
LUM42_17465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_17470	COG3706	GGDEF domain
LUM42_17485	COG0583	DNA-binding transcription factor activity
LUM42_17490	COG4221	oxidoreductase activity
LUM42_17495	COG0583	DNA-binding transcription factor activity
LUM42_17500	COG1486	melibiose metabolic process
LUM42_17570	COG2176	DNA-directed DNA polymerase activity
LUM42_17585	COG0443	Heat shock 70 kDa protein
LUM42_17590	COG0095	Lipoate-protein ligase
LUM42_17595	COG0243	molybdopterin cofactor binding
LUM42_17600	COG0437	4 iron, 4 sulfur cluster binding
LUM42_17605	COG3302	dmso reductase anchor subunit
LUM42_17615	COG2221	Nitrite and sulphite reductase 4Fe-4S
LUM42_17615	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LUM42_17640	COG2376	Dihydroxyacetone kinase
LUM42_17645	COG1461	Dihydroxyacetone kinase
LUM42_17655	COG3284	Transcriptional regulator
LUM42_17665	COG3722	fumarate hydratase activity
LUM42_17670	COG0246	Mannitol dehydrogenase
LUM42_17675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_17675	COG2213	PTS system mannitol-specific
LUM42_17680	COG0739	heme binding
LUM42_17695	COG0363	glucosamine-6-phosphate deaminase activity
LUM42_17725	COG0402	S-adenosylhomocysteine deaminase activity
LUM42_17730	COG2259	Doxx family
LUM42_17740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LUM42_17750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LUM42_17755	COG1301	dicarboxylic acid transport
LUM42_17760	COG1917	Cupin 2, conserved barrel domain protein
LUM42_17760	COG2169	Transcriptional regulator
LUM42_17790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_17800	COG0583	DNA-binding transcription factor activity
LUM42_17805	COG1342	Belongs to the UPF0251 family
LUM42_17815	COG0583	DNA-binding transcription factor activity
LUM42_17820	COG3384	dioxygenase
LUM42_17835	COG4774	siderophore transport
LUM42_17840	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LUM42_17845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_17850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_17855	COG1120	ATPase activity
LUM42_17865	COG0583	DNA-binding transcription factor activity
LUM42_17870	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_17885	COG0519	Catalyzes the synthesis of GMP from XMP
LUM42_17910	COG3152	Membrane
LUM42_17930	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LUM42_17945	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LUM42_17960	COG1620	l-lactate permease
LUM42_17965	COG0583	DNA-binding transcription factor activity
LUM42_17970	COG4172	Belongs to the ABC transporter superfamily
LUM42_17980	COG1067	ATP-dependent peptidase activity
LUM42_17990	COG2211	Major facilitator Superfamily
LUM42_17995	COG0668	transmembrane transport
LUM42_18000	COG0569	domain protein
LUM42_18005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LUM42_18015	COG3123	guanosine phosphorylase activity
LUM42_18025	COG2814	Major facilitator Superfamily
LUM42_18145	COG2205	protein histidine kinase activity
LUM42_18150	COG0745	RESPONSE REGULATOR receiver
LUM42_18155	COG1741	Belongs to the pirin family
LUM42_18215	COG3706	GGDEF domain
LUM42_18225	COG1846	Transcriptional regulator
LUM42_18230	COG2315	Protein conserved in bacteria
LUM42_18235	COG0835	chemotaxis
LUM42_18235	COG0784	Response regulator, receiver
LUM42_18240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LUM42_18265	COG1215	transferase activity, transferring glycosyl groups
LUM42_18280	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LUM42_18280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LUM42_18285	COG0367	asparagine synthase
LUM42_18300	COG0251	oxidation-reduction process
LUM42_18320	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LUM42_18335	COG2962	Rard protein
LUM42_18340	COG1522	sequence-specific DNA binding
LUM42_18345	COG2197	response regulator
LUM42_18350	COG0393	Putative heavy-metal-binding
LUM42_18355	COG0823	Involved in the tonB-independent uptake of proteins
LUM42_18360	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LUM42_18365	COG0534	Mate efflux family protein
LUM42_18375	COG1653	transport
LUM42_18380	COG3842	ATPase activity
LUM42_18385	COG0395	ABC-type sugar transport system, permease component
LUM42_18390	COG1175	transmembrane transport
LUM42_18405	COG0840	transmembrane signaling receptor activity
LUM42_18415	COG0800	Aldolase
LUM42_18420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_18430	COG0235	Class ii aldolase
LUM42_18435	COG3254	rhamnose metabolic process
LUM42_18440	COG4806	L-rhamnose isomerase
LUM42_18445	COG1070	Carbohydrate kinase
LUM42_18450	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
LUM42_18480	COG1917	Cupin 2, conserved barrel domain protein
LUM42_18490	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_18500	COG0517	IMP dehydrogenase activity
LUM42_18520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUM42_18530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_18570	COG3842	ATPase activity
LUM42_18580	COG1175	transmembrane transport
LUM42_18585	COG3833	ABC-type maltose transport systems, permease component
LUM42_18610	COG1349	DNA-binding transcription factor activity
LUM42_18630	COG2354	Protein conserved in bacteria
LUM42_18635	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LUM42_18640	COG0418	dihydroorotase activity
LUM42_18645	COG0633	Ferredoxin
LUM42_18645	COG3217	Mosc domain protein beta barrel domain protein
LUM42_18675	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LUM42_18680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_18690	COG0848	biopolymer transport protein
LUM42_18695	COG0811	peptide transport
LUM42_18700	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LUM42_18710	COG3721	Heme iron utilization protein
LUM42_18715	COG0748	coenzyme F420 binding
LUM42_18725	COG0531	amino acid
LUM42_18730	COG1522	sequence-specific DNA binding
LUM42_18750	COG1151	hydroxylamine reductase activity
LUM42_18755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LUM42_18760	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LUM42_18785	COG5002	protein histidine kinase activity
LUM42_18785	COG0784	Response regulator, receiver
LUM42_18785	COG2205	protein histidine kinase activity
LUM42_18805	COG1765	OsmC-like protein
LUM42_18815	COG0110	maltose O-acetyltransferase activity
LUM42_18845	COG3121	Chaperone
LUM42_18850	COG0579	oxidoreductase
LUM42_18870	COG0583	DNA-binding transcription factor activity
LUM42_18875	COG0798	PFAM Bile acid sodium symporter
LUM42_18880	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LUM42_18890	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LUM42_18940	COG0513	Belongs to the DEAD box helicase family
LUM42_18955	COG0840	transmembrane signaling receptor activity
LUM42_18975	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LUM42_18980	COG1811	Na channel or pump
LUM42_19000	COG2985	domain, Protein
LUM42_19010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LUM42_19055	COG3122	Protein conserved in bacteria
LUM42_19060	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LUM42_19070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LUM42_19075	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LUM42_19075	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LUM42_19080	COG0509	glycine decarboxylation via glycine cleavage system
LUM42_19085	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LUM42_19095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LUM42_19110	COG5001	Diguanylate cyclase
LUM42_19110	COG3300	MHYT domain
LUM42_19115	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_19155	COG0484	heat shock protein binding
LUM42_19165	COG5001	Diguanylate cyclase
LUM42_19165	COG1716	ATPase activity
LUM42_19170	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LUM42_19180	COG4181	ATPase activity
LUM42_19185	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LUM42_19195	COG1984	allophanate hydrolase subunit 2
LUM42_19205	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LUM42_19210	COG3447	MASE1 domain protein
LUM42_19210	COG5001	Diguanylate cyclase
LUM42_19210	COG5002	protein histidine kinase activity
LUM42_19220	COG0840	transmembrane signaling receptor activity
LUM42_19225	COG0814	amino acid
LUM42_19230	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LUM42_19235	COG0513	Belongs to the DEAD box helicase family
LUM42_19240	COG1309	transcriptional regulator
LUM42_19250	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LUM42_19265	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LUM42_19295	COG0840	transmembrane signaling receptor activity
LUM42_19310	COG0583	DNA-binding transcription factor activity
LUM42_19315	COG0697	spore germination
LUM42_19340	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LUM42_19355	COG0406	alpha-ribazole phosphatase activity
LUM42_19360	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LUM42_19365	COG1454	alcohol dehydrogenase
LUM42_19370	COG1609	Transcriptional regulator
LUM42_19370	COG2207	Transcriptional regulator
LUM42_19380	COG3634	alkyl hydroperoxide reductase activity
LUM42_19385	COG0450	alkyl hydroperoxide reductase
LUM42_19400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LUM42_19405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LUM42_19410	COG1960	acyl-CoA dehydrogenase activity
LUM42_19420	COG0183	Belongs to the thiolase family
LUM42_19430	COG1960	acyl-CoA dehydrogenase activity
LUM42_19435	COG1024	Enoyl-CoA hydratase
LUM42_19440	COG1024	Enoyl-CoA hydratase
LUM42_19450	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_19460	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_19470	COG0653	protein targeting
LUM42_19485	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LUM42_19505	COG0512	Glutamine amidotransferase of anthranilate synthase
LUM42_19505	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LUM42_19510	COG1454	alcohol dehydrogenase
LUM42_19515	COG1464	Belongs to the NlpA lipoprotein family
LUM42_19535	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LUM42_19540	COG0573	inorganic phosphate transmembrane transporter activity
LUM42_19550	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LUM42_19555	COG0625	glutathione transferase activity
LUM42_19615	COG2721	sulfolactate sulfo-lyase activity
LUM42_19630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LUM42_19640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LUM42_19645	COG1280	lysine exporter protein (LysE YggA)
LUM42_19650	COG0400	carboxylic ester hydrolase activity
LUM42_19655	COG0435	Glutathione S-transferase
LUM42_19660	COG0583	DNA-binding transcription factor activity
LUM42_19665	COG4145	pantothenate transmembrane transporter activity
LUM42_19675	COG2423	ornithine cyclodeaminase activity
LUM42_19690	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LUM42_19715	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LUM42_19725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LUM42_19745	COG2207	Transcriptional regulator
LUM42_19765	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LUM42_19775	COG0488	(ABC) transporter
LUM42_19925	COG1252	NADH dehydrogenase
LUM42_19935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LUM42_19940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LUM42_19945	COG4232	protein-disulfide reductase activity
LUM42_19955	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LUM42_19960	COG0110	maltose O-acetyltransferase activity
LUM42_19975	COG3008	intermembrane lipid transfer
LUM42_19975	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LUM42_19980	COG2995	paraquat-inducible protein a
LUM42_19985	COG0318	PFAM AMP-dependent synthetase and ligase
LUM42_19995	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_20000	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LUM42_20010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LUM42_20020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUM42_20030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LUM42_20035	COG0583	DNA-binding transcription factor activity
LUM42_20045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LUM42_20060	COG0513	Belongs to the DEAD box helicase family
LUM42_20065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LUM42_20085	COG0672	)-iron permease
LUM42_20090	COG4633	Protein conserved in bacteria
LUM42_20095	COG4628	conserved protein (DUF2132)
LUM42_20135	COG0789	Transcriptional regulator
LUM42_20140	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LUM42_20195	COG0454	-acetyltransferase
LUM42_20205	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_20240	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LUM42_20250	COG0494	nUDIX hydrolase
LUM42_20255	COG1280	lysine exporter protein (LysE YggA)
LUM42_20265	COG0456	acetyltransferase
LUM42_20275	COG1335	isochorismatase
LUM42_20305	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUM42_20310	COG1309	transcriptional regulator
LUM42_20320	COG0583	DNA-binding transcription factor activity
LUM42_20330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LUM42_20345	COG2897	thiosulfate sulfurtransferase activity
LUM42_20350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LUM42_20360	COG0302	gtp cyclohydrolase
LUM42_20365	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUM42_20365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LUM42_20370	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LUM42_20375	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LUM42_20390	COG1011	Hydrolase
LUM42_20395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LUM42_20405	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUM42_20410	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUM42_20415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LUM42_20425	COG3842	ATPase activity
LUM42_20445	COG2866	Carboxypeptidase
LUM42_20470	COG4166	transmembrane transport
LUM42_20475	COG4174	ABC transporter (Permease)
LUM42_20480	COG4239	(ABC) transporter, permease
LUM42_20485	COG4172	Belongs to the ABC transporter superfamily
LUM42_20490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LUM42_20510	COG3706	GGDEF domain
LUM42_20510	COG4251	negative regulation of phosphorylation
LUM42_20510	COG2203	Gaf domain
LUM42_20510	COG5001	Diguanylate cyclase
LUM42_20520	COG2199	diguanylate cyclase activity
LUM42_20535	COG2501	S4 domain
LUM42_20590	COG3710	Transcriptional regulator
LUM42_20620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_20625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LUM42_20625	COG2207	Transcriptional regulator
LUM42_20635	COG2233	PERMEase
LUM42_20660	COG0765	amino acid transport
LUM42_20665	COG0765	amino acid transport
LUM42_20695	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LUM42_20720	COG0402	S-adenosylhomocysteine deaminase activity
LUM42_20725	COG2351	hydroxyisourate hydrolase activity
LUM42_20755	COG1079	Belongs to the binding-protein-dependent transport system permease family
LUM42_20760	COG4603	Belongs to the binding-protein-dependent transport system permease family
LUM42_20765	COG3845	ABC transporter
LUM42_20770	COG1309	transcriptional regulator
LUM42_20790	COG2199	diguanylate cyclase activity
LUM42_20805	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LUM42_20810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LUM42_20835	COG3140	Belongs to the UPF0181 family
LUM42_20840	COG0023	Translation Initiation Factor
LUM42_20855	COG1181	Belongs to the D-alanine--D-alanine ligase family
LUM42_20865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUM42_20865	COG1042	CoA-binding domain protein
LUM42_20865	COG0045	succinate-CoA ligase (ADP-forming) activity
LUM42_20870	COG0583	DNA-binding transcription factor activity
LUM42_20875	COG4771	TonB-dependent receptor
LUM42_20885	COG4533	DNA binding
LUM42_20895	COG2050	protein possibly involved in aromatic compounds catabolism
LUM42_20905	COG2824	Alkylphosphonate utilization operon protein PhnA
LUM42_20920	COG0737	Belongs to the 5'-nucleotidase family
LUM42_20925	COG3593	DNA synthesis involved in DNA repair
LUM42_20935	COG0583	DNA-binding transcription factor activity
LUM42_20940	COG2116	formate transmembrane transporter activity
LUM42_20945	COG2353	YceI-like domain
LUM42_20950	COG3038	cytochrome b561
LUM42_20975	COG5001	Diguanylate cyclase
LUM42_20985	COG0243	molybdopterin cofactor binding
LUM42_20990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LUM42_20995	COG0784	Response regulator, receiver
LUM42_20995	COG2205	protein histidine kinase activity
LUM42_20995	COG5002	protein histidine kinase activity
LUM42_21000	COG3437	response regulator, receiver
LUM42_21010	COG2207	Transcriptional regulator
LUM42_21015	COG1064	alcohol dehydrogenase
LUM42_21020	COG1028	Short-chain dehydrogenase reductase Sdr
LUM42_21025	COG1846	Transcriptional regulator
LUM42_21030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LUM42_21035	COG0523	cobalamin synthesis protein
LUM42_21050	COG0156	8-amino-7-oxononanoate synthase activity
LUM42_21055	COG0784	Response regulator, receiver
LUM42_21055	COG2205	protein histidine kinase activity
LUM42_21060	COG0419	ATPase involved in DNA repair
LUM42_21065	COG0420	3'-5' exonuclease activity
LUM42_21070	COG1609	Transcriptional regulator
LUM42_21075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_21075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LUM42_21080	COG1105	Belongs to the carbohydrate kinase PfkB family
LUM42_21085	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LUM42_21085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUM42_21085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LUM42_21090	COG4067	protein conserved in archaea
LUM42_21090	COG0189	ligase activity
LUM42_21100	COG0602	queuosine metabolic process
LUM42_21105	COG1328	CTP reductase activity
LUM42_21190	COG1073	alpha beta
LUM42_21195	COG0583	DNA-binding transcription factor activity
LUM42_21200	COG0454	-acetyltransferase
LUM42_21210	COG2207	Transcriptional regulator
LUM42_21220	COG1073	alpha beta
LUM42_21225	COG1073	alpha beta
LUM42_21230	COG1902	pentaerythritol trinitrate reductase activity
LUM42_21275	COG0583	DNA-binding transcription factor activity
LUM42_21280	COG1280	lysine exporter protein (LysE YggA)
LUM42_21285	COG0745	RESPONSE REGULATOR receiver
LUM42_21295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LUM42_21300	COG0840	transmembrane signaling receptor activity
LUM42_21320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUM42_21325	COG0840	transmembrane signaling receptor activity
LUM42_21330	COG2814	Major facilitator Superfamily
LUM42_21345	COG3069	C4-dicarboxylate transmembrane transporter activity
LUM42_21350	COG2197	response regulator
LUM42_21355	COG3850	Histidine kinase
LUM42_21370	COG0243	molybdopterin cofactor binding
LUM42_21380	COG3005	denitrification pathway
LUM42_21390	COG4166	transmembrane transport
LUM42_21410	COG0183	Belongs to the thiolase family
LUM42_21420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUM42_21425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LUM42_21450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LUM42_21460	COG2207	Transcriptional regulator
LUM42_21465	COG1979	alcohol dehydrogenase
LUM42_21475	COG2205	protein histidine kinase activity
LUM42_21475	COG2198	Histidine kinase
LUM42_21475	COG0784	Response regulator, receiver
LUM42_21480	COG1879	ABC-type sugar transport system periplasmic component
LUM42_21485	COG1803	Methylglyoxal synthase
LUM42_21490	COG1335	isochorismatase
LUM42_21495	COG0210	DNA helicase
LUM42_21535	COG1289	transmembrane transporter activity
LUM42_21550	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LUM42_21555	COG4149	molybdate abc transporter
LUM42_21560	COG0725	ABC transporter, periplasmic molybdate-binding protein
LUM42_21565	COG1492	cobalamin metabolic process
LUM42_21585	COG0784	Response regulator, receiver
LUM42_21585	COG5002	protein histidine kinase activity
LUM42_21590	COG1879	ABC-type sugar transport system periplasmic component
LUM42_21595	COG2827	Endonuclease containing a URI domain
LUM42_21600	COG3132	Protein of unknown function, DUF480
LUM42_21615	COG4974	Belongs to the 'phage' integrase family
LUM42_21770	COG2184	nucleotidyltransferase activity
LUM42_21775	COG4695	Portal protein
LUM42_21815	COG4386	tail sheath protein
LUM42_21865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LUM42_21870	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LUM42_21875	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LUM42_21880	COG0247	lactate metabolic process
LUM42_21895	COG0297	glycogen (starch) synthase activity
LUM42_21895	COG0438	transferase activity, transferring glycosyl groups
LUM42_21900	COG0438	transferase activity, transferring glycosyl groups
LUM42_21950	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LUM42_21955	COG3118	belongs to the thioredoxin family
LUM42_21985	COG1648	precorrin-2 dehydrogenase activity
LUM42_21985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LUM42_22000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LUM42_22005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LUM42_22010	COG4160	amino acid transport
LUM42_22015	COG4215	(ABC) transporter
LUM42_22020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_22025	COG1126	abc transporter atp-binding protein
LUM42_22055	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LUM42_22060	COG1120	ATPase activity
LUM42_22075	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LUM42_22085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LUM42_22100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUM42_22110	COG1070	Carbohydrate kinase
LUM42_22120	COG2390	Transcriptional regulator
LUM42_22125	COG1294	oxidase, subunit
LUM42_22130	COG1271	oxidase subunit
LUM42_22135	COG0243	molybdopterin cofactor binding
LUM42_22140	COG3781	membrane
LUM42_22145	COG0583	DNA-binding transcription factor activity
LUM42_22150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LUM42_22165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LUM42_22175	COG0330	HflC and HflK could
LUM42_22195	COG2207	Transcriptional regulator
LUM42_22195	COG1917	Cupin 2, conserved barrel domain protein
LUM42_22200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LUM42_22215	COG1609	Transcriptional regulator
LUM42_22215	COG2207	Transcriptional regulator
LUM42_22220	COG4604	ABC transporter, ATP-binding protein
LUM42_22225	COG4605	iron ion homeostasis
LUM42_22230	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LUM42_22240	COG0121	glutamine amidotransferase
LUM42_22255	COG5380	lipid catabolic process
LUM42_22260	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LUM42_22265	COG0840	transmembrane signaling receptor activity
LUM42_22270	COG1522	sequence-specific DNA binding
LUM42_22290	COG2814	Major facilitator Superfamily
LUM42_22300	COG0840	transmembrane signaling receptor activity
LUM42_22315	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LUM42_22320	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LUM42_22325	COG3279	Response regulator of the LytR AlgR family
LUM42_22330	COG3275	phosphorelay sensor kinase activity
LUM42_22335	COG4989	oxidoreductase activity
LUM42_22350	COG0366	Alpha amylase catalytic
LUM42_22355	COG3227	Zinc metalloprotease (Elastase)
LUM42_22360	COG3047	cAMP biosynthetic process
LUM42_22370	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LUM42_22380	COG0351	phosphomethylpyrimidine kinase
LUM42_22385	COG1116	anion transmembrane transporter activity
LUM42_22390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LUM42_22395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LUM42_22400	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LUM42_22415	COG1132	(ABC) transporter
LUM42_22420	COG1132	(ABC) transporter
LUM42_22430	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LUM42_22435	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LUM42_22455	COG1278	Cold shock
LUM42_22460	COG1063	alcohol dehydrogenase
LUM42_22465	COG0156	8-amino-7-oxononanoate synthase activity
LUM42_22470	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_22475	COG3284	Transcriptional regulator
LUM42_22485	COG0346	lactoylglutathione lyase activity
LUM42_22505	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LUM42_22515	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LUM42_22520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LUM42_22525	COG0363	glucosamine-6-phosphate deaminase activity
LUM42_22530	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LUM42_22570	COG0531	amino acid
LUM42_22585	COG1929	Belongs to the glycerate kinase type-1 family
LUM42_22590	COG2610	gluconate transmembrane transporter activity
LUM42_22595	COG3835	regulator
LUM42_22600	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUM42_22605	COG4533	DNA binding
LUM42_22660	COG3188	usher protein
LUM42_22665	COG3121	Chaperone
LUM42_22685	COG1566	PFAM secretion protein HlyD family protein
LUM42_22700	COG1686	Belongs to the peptidase S11 family
LUM42_22710	COG0765	amino acid transport
LUM42_22725	COG1522	sequence-specific DNA binding
LUM42_22730	COG0010	Belongs to the arginase family
LUM42_22735	COG1166	arginine decarboxylase activity
LUM42_22745	COG4175	Glycine betaine
LUM42_22750	COG4176	ABC-type proline glycine betaine transport system permease component
LUM42_22755	COG2113	Glycine betaine
LUM42_22775	COG2239	Acts as a magnesium transporter
LUM42_22780	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LUM42_22785	COG0459	protein refolding
LUM42_22795	COG0113	porphobilinogen synthase activity
LUM42_22805	COG3437	response regulator, receiver
LUM42_22805	COG0784	Response regulator, receiver
LUM42_22830	COG0527	aspartate kinase activity
LUM42_22835	COG0662	Cupin 2, conserved barrel domain protein
LUM42_22840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LUM42_22845	COG0456	acetyltransferase
LUM42_22850	COG4977	sequence-specific DNA binding
LUM42_22850	COG1917	Cupin 2, conserved barrel domain protein
LUM42_22855	COG0861	Integral membrane protein TerC family
LUM42_22865	COG0534	Mate efflux family protein
LUM42_22870	COG2154	pterin-4-alpha-carbinolamine dehydratase
LUM42_22875	COG3186	Phenylalanine-4-hydroxylase
LUM42_22880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LUM42_22915	COG1022	Amp-dependent synthetase and ligase
LUM42_22950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LUM42_22955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LUM42_22955	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LUM42_22965	COG2197	response regulator
LUM42_22970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LUM42_22970	COG2205	protein histidine kinase activity
LUM42_22975	COG5001	Diguanylate cyclase
LUM42_22975	COG3300	MHYT domain
LUM42_23005	COG3036	rescue of stalled ribosome
LUM42_23010	COG1278	Cold shock
LUM42_23015	COG4681	YaeQ
LUM42_23020	COG3706	GGDEF domain
LUM42_23025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LUM42_23025	COG1017	nitric oxide dioxygenase activity
LUM42_23030	COG3604	Transcriptional regulator
LUM42_23040	COG2195	Cleaves the N-terminal amino acid of tripeptides
LUM42_23045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LUM42_23055	COG0366	Alpha amylase catalytic
LUM42_23070	COG0840	transmembrane signaling receptor activity
LUM42_23075	COG0714	Associated with various cellular activities
LUM42_23095	COG2304	oxidoreductase activity
LUM42_23110	COG5001	Diguanylate cyclase
LUM42_23120	COG0784	Response regulator, receiver
LUM42_23120	COG5002	protein histidine kinase activity
LUM42_23120	COG2205	protein histidine kinase activity
LUM42_23135	COG3724	N-succinylarginine dihydrolase activity
LUM42_23140	COG1012	belongs to the aldehyde dehydrogenase family
LUM42_23165	COG4948	Mandelate Racemase Muconate Lactonizing
LUM42_23190	COG0583	DNA-binding transcription factor activity
LUM42_23200	COG3171	Protein conserved in bacteria
LUM42_23205	COG0589	response to stress
LUM42_23215	COG3530	Putative quorum-sensing-regulated virulence factor
LUM42_23225	COG0579	oxidoreductase
LUM42_23240	COG2204	response regulator
LUM42_23270	COG5001	Diguanylate cyclase
LUM42_23270	COG3300	MHYT domain
LUM42_23275	COG2271	Major facilitator Superfamily
LUM42_23280	COG0584	glycerophosphoryl diester phosphodiesterase
LUM42_23285	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LUM42_23290	COG0583	DNA-binding transcription factor activity
LUM42_23295	COG1609	Transcriptional regulator
LUM42_23300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LUM42_23305	COG1879	ABC-type sugar transport system periplasmic component
LUM42_23310	COG1172	Belongs to the binding-protein-dependent transport system permease family
LUM42_23315	COG1129	ABC transporter
LUM42_23320	COG1869	D-ribose catabolic process
LUM42_23340	COG3501	Rhs element vgr protein
LUM42_23340	COG3409	Peptidoglycan-binding domain 1 protein
LUM42_23410	COG3501	Rhs element vgr protein
LUM42_23435	COG3829	transcription factor binding
LUM42_23510	COG1846	Transcriptional regulator
LUM42_23525	COG0564	pseudouridine synthase activity
LUM42_23530	COG1309	transcriptional regulator
LUM42_23535	COG2130	NADP-dependent
LUM42_23550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LUM42_23580	COG3842	ATPase activity
LUM42_23590	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LUM42_23595	COG0656	L-ascorbic acid biosynthetic process
LUM42_23600	COG1902	pentaerythritol trinitrate reductase activity
LUM42_23605	COG0583	DNA-binding transcription factor activity
LUM42_23610	COG2814	Major facilitator Superfamily
LUM42_23630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LUM42_23645	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LUM42_23655	COG4702	Belongs to the UPF0303 family
LUM42_23660	COG0673	inositol 2-dehydrogenase activity
LUM42_23665	COG1349	DNA-binding transcription factor activity
LUM42_23675	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LUM42_23695	COG3240	lipase activity
LUM42_23700	COG3477	response to acidic pH
LUM42_23705	COG0697	spore germination
LUM42_23710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LUM42_23725	COG1917	Cupin 2, conserved barrel domain protein
LUM42_23725	COG2207	Transcriptional regulator
LUM42_23745	COG5002	protein histidine kinase activity
LUM42_23745	COG3447	MASE1 domain protein
LUM42_23745	COG5001	Diguanylate cyclase
LUM42_23755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LUM42_23770	COG0109	protoheme IX farnesyltransferase activity
LUM42_23805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LUM42_23810	COG1565	acr, cog1565
LUM42_23810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LUM42_23815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LUM42_23820	COG1902	pentaerythritol trinitrate reductase activity
LUM42_23830	COG1280	lysine exporter protein (LysE YggA)
LUM42_23855	COG0179	Fumarylacetoacetate (FAA) hydrolase
LUM42_23860	COG1846	Transcriptional regulator
LUM42_23865	COG1764	response to oxidative stress
LUM42_23875	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LUM42_23885	COG2814	Major facilitator Superfamily
LUM42_23890	COG0583	DNA-binding transcription factor activity
LUM42_23895	COG5001	Diguanylate cyclase
LUM42_23900	COG0739	heme binding
LUM42_23915	COG0659	secondary active sulfate transmembrane transporter activity
LUM42_23920	COG3314	Sporulation integral membrane protein YlbJ
LUM42_23930	COG2199	diguanylate cyclase activity
LUM42_23935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LUM42_23940	COG0581	inorganic phosphate transmembrane transporter activity
LUM42_23945	COG0573	inorganic phosphate transmembrane transporter activity
LUM42_23950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LUM42_23960	COG0513	Belongs to the DEAD box helicase family
LUM42_23970	COG1388	LysM domain
LUM42_23970	COG1376	ErfK ybiS ycfS ynhG family protein
LUM42_23975	COG0415	Belongs to the DNA photolyase family
LUM42_23980	COG0789	Transcriptional regulator
LUM42_23985	COG3272	Protein of unknown function (DUF1722)
LUM42_23990	COG0813	purine-nucleoside phosphorylase activity
LUM42_24005	COG3706	GGDEF domain
LUM42_24015	COG1566	PFAM secretion protein HlyD family protein
LUM42_24050	COG0786	glutamate:sodium symporter activity
LUM42_24075	COG1162	GTPase activity
LUM42_24080	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LUM42_24095	COG4580	involved in the transport of maltose and maltodextrins
LUM42_24105	COG1132	(ABC) transporter
LUM42_24125	COG3383	formate dehydrogenase (NAD+) activity
LUM42_24140	COG0840	transmembrane signaling receptor activity
LUM42_24150	COG1131	(ABC) transporter
LUM42_24155	COG2188	Transcriptional regulator
LUM42_24165	COG3033	Beta-eliminating lyase
LUM42_24170	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LUM42_24175	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LUM42_24180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LUM42_24185	COG0471	metal ion transport
LUM42_24210	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LUM42_24260	COG3501	Rhs element vgr protein
LUM42_24270	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LUM42_24275	COG1640	4-alpha-glucanotransferase
LUM42_24280	COG0058	SHG alpha-glucan phosphorylase activity