locus-tag	class	description
MID13_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MID13_00010	COG0592	DNA-directed DNA polymerase activity
MID13_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MID13_00020	COG0187	DNA topoisomerase II activity
MID13_00025	COG4667	esterase of the alpha-beta hydrolase superfamily
MID13_00030	COG0071	Belongs to the small heat shock protein (HSP20) family
MID13_00035	COG3977	Valine--pyruvate aminotransferase
MID13_00055	COG4964	Belongs to the GSP D family
MID13_00120	COG0366	Alpha amylase catalytic
MID13_00125	COG0751	glycine-tRNA ligase activity
MID13_00130	COG0752	glycyl-tRNA synthetase alpha subunit
MID13_00135	COG2119	membrane
MID13_00145	COG0425	Belongs to the sulfur carrier protein TusA family
MID13_00160	COG0604	alcohol dehydrogenase
MID13_00165	COG0183	Belongs to the thiolase family
MID13_00170	COG1024	Enoyl-CoA hydratase
MID13_00170	COG1250	3-hydroxyacyl-CoA dehydrogenase
MID13_00175	COG1739	Uncharacterized protein family UPF0029
MID13_00180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MID13_00185	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
MID13_00230	COG0583	DNA-binding transcription factor activity
MID13_00235	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MID13_00240	COG2960	long-chain fatty acid transporting porin activity
MID13_00245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MID13_00250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MID13_00255	COG1309	transcriptional regulator
MID13_00305	COG0601	transmembrane transport
MID13_00310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MID13_00355	COG1805	sodium ion transport
MID13_00365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MID13_00370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MID13_00375	COG0339	signal peptide processing
MID13_00380	COG1522	sequence-specific DNA binding
MID13_00385	COG5002	protein histidine kinase activity
MID13_00385	COG5001	Diguanylate cyclase
MID13_00390	COG0742	ribosomal rna small subunit methyltransferase
MID13_00405	COG0589	response to stress
MID13_00410	COG1528	Iron-storage protein
MID13_00420	COG2081	HI0933 family
MID13_00430	COG1322	Protein conserved in bacteria
MID13_00435	COG2226	methyltransferase
MID13_00440	COG3165	ubiquinone biosynthetic process from chorismate
MID13_00445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MID13_00450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MID13_00455	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MID13_00460	COG0805	protein transport
MID13_00465	COG0084	hydrolase, TatD family'
MID13_00480	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MID13_00480	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MID13_00505	COG3078	GTPase activator activity
MID13_00530	COG3852	Histidine kinase
MID13_00540	COG0174	glutamine synthetase
MID13_00545	COG1217	gtp-binding protein TYPA
MID13_00560	COG1295	ribonuclease BN
MID13_00565	COG1490	D-aminoacyl-tRNA deacylase activity
MID13_00570	COG0456	acetyltransferase
MID13_00580	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MID13_00590	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MID13_00595	COG3031	protein transport across the cell outer membrane
MID13_00605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MID13_00610	COG1459	type II secretion system
MID13_00615	COG2165	general secretion pathway protein
MID13_00620	COG2165	general secretion pathway protein
MID13_00625	COG2165	general secretion pathway protein
MID13_00630	COG4795	General secretion pathway protein
MID13_00635	COG3156	type II secretion system protein K
MID13_00640	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
MID13_00645	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
MID13_00660	COG1218	3'(2'),5'-bisphosphate nucleotidase
MID13_00665	COG0494	nUDIX hydrolase
MID13_00670	COG0316	Belongs to the HesB IscA family
MID13_00670	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
MID13_00680	COG0596	Alpha beta hydrolase
MID13_00690	COG2183	response to ionizing radiation
MID13_00695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MID13_00700	COG1278	Cold shock
MID13_00720	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MID13_00730	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MID13_00735	COG1758	RNA polymerase activity
MID13_00740	COG0194	GDP metabolic process
MID13_00745	COG2252	PERMEase
MID13_00775	COG1278	Cold shock
MID13_00785	COG1561	YicC-like family, N-terminal region
MID13_00790	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MID13_00795	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MID13_00800	COG1560	Kdo2-lipid A biosynthetic process
MID13_00805	COG1309	transcriptional regulator
MID13_00815	COG2003	Belongs to the UPF0758 family
MID13_00820	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MID13_00825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MID13_00835	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MID13_00850	COG0859	PFAM glycosyl transferase family 9
MID13_00855	COG0463	Glycosyl transferase, family 2
MID13_00860	COG0859	PFAM glycosyl transferase family 9
MID13_00865	COG3642	lipopolysaccharide core region biosynthetic process
MID13_00920	COG1051	belongs to the nudix hydrolase family
MID13_00935	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MID13_00955	COG1519	Transferase
MID13_00960	COG0859	PFAM glycosyl transferase family 9
MID13_00965	COG1560	Kdo2-lipid A biosynthetic process
MID13_00985	COG4942	peptidase
MID13_00990	COG1045	serine acetyltransferase
MID13_01000	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MID13_01005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MID13_01025	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MID13_01030	COG1596	polysaccharide export
MID13_01070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MID13_01075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MID13_01085	COG1216	Glycosyl transferase, family 2
MID13_01110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MID13_01120	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MID13_01130	COG0534	Mate efflux family protein
MID13_01155	COG5001	Diguanylate cyclase
MID13_01160	COG1285	pathogenesis
MID13_01170	COG1509	lysine 2,3-aminomutase activity
MID13_01175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MID13_01190	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
MID13_01195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MID13_01200	COG1053	succinate dehydrogenase
MID13_01205	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MID13_01215	COG0840	transmembrane signaling receptor activity
MID13_01220	COG0490	domain, Protein
MID13_01220	COG0471	metal ion transport
MID13_01225	COG0688	phosphatidylethanolamine metabolic process
MID13_01230	COG1162	GTPase activity
MID13_01320	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MID13_01325	COG0802	atpase or kinase
MID13_01330	COG0860	N-Acetylmuramoyl-L-alanine amidase
MID13_01335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MID13_01340	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MID13_01345	COG1923	regulation of RNA biosynthetic process
MID13_01350	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MID13_01355	COG0330	HflC and HflK could
MID13_01360	COG0330	HflC and HflK could
MID13_01365	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
MID13_01370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MID13_01375	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
MID13_01380	COG0402	S-adenosylhomocysteine deaminase activity
MID13_01385	COG0557	exoribonuclease II activity
MID13_01390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MID13_01405	COG0359	binds to the 23S rRNA
MID13_01420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MID13_01430	COG0432	Pfam Uncharacterised protein family UPF0047
MID13_01435	COG0166	Belongs to the GPI family
MID13_01445	COG0735	belongs to the Fur family
MID13_01585	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MID13_01590	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MID13_01595	COG0175	sulfate reduction
MID13_01675	COG0527	aspartate kinase activity
MID13_01680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MID13_01690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MID13_01700	COG2197	response regulator
MID13_01705	COG0629	single-stranded DNA binding
MID13_01710	COG2199	diguanylate cyclase activity
MID13_01710	COG2200	EAL domain
MID13_01735	COG3409	Peptidoglycan-binding domain 1 protein
MID13_01735	COG3267	Type II secretory pathway component ExeA
MID13_01745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MID13_01750	COG1459	type II secretion system
MID13_01760	COG2165	general secretion pathway protein
MID13_01765	COG2165	general secretion pathway protein
MID13_01795	COG1077	Cell shape determining protein MreB Mrl
MID13_01800	COG1792	Involved in formation and maintenance of cell shape
MID13_01805	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MID13_01810	COG0424	maF-like protein
MID13_01825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MID13_01830	COG0312	modulator of DNA gyrase
MID13_01835	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MID13_01840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
MID13_01855	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MID13_01860	COG0589	response to stress
MID13_01875	COG1438	arginine binding
MID13_01880	COG0039	L-malate dehydrogenase activity
MID13_01890	COG0142	geranyltranstransferase activity
MID13_01895	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MID13_01900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MID13_01905	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MID13_01910	COG2966	Psort location CytoplasmicMembrane, score
MID13_01915	COG3610	response to peptide
MID13_01930	COG2967	ApaG domain
MID13_01935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MID13_01940	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MID13_01945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MID13_01950	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
MID13_01955	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MID13_01970	COG0066	3-isopropylmalate dehydratase activity
MID13_01980	COG0473	3-isopropylmalate dehydrogenase activity
MID13_01985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MID13_02020	COG1022	Amp-dependent synthetase and ligase
MID13_02025	COG0028	Belongs to the TPP enzyme family
MID13_02035	COG3706	GGDEF domain
MID13_02045	COG0469	pyruvate kinase activity
MID13_02050	COG1349	DNA-binding transcription factor activity
MID13_02055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MID13_02060	COG2873	o-acetylhomoserine
MID13_02080	COG1610	YqeY-like protein
MID13_02085	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MID13_02090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MID13_02095	COG0596	Alpha beta hydrolase
MID13_02100	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MID13_02105	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MID13_02110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MID13_02115	COG1968	undecaprenyl-diphosphatase activity
MID13_02125	COG3267	Type II secretory pathway component ExeA
MID13_02125	COG3409	Peptidoglycan-binding domain 1 protein
MID13_02135	COG4991	sh3 domain protein
MID13_02140	COG0306	phosphate transporter
MID13_02145	COG1392	Phosphate transport regulator
MID13_02150	COG3025	triphosphatase activity
MID13_02155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MID13_02165	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MID13_02170	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MID13_02170	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MID13_02175	COG1538	Outer membrane efflux protein
MID13_02180	COG0494	nUDIX hydrolase
MID13_02185	COG3151	Protein conserved in bacteria
MID13_02195	COG3150	esterase
MID13_02210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MID13_02215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MID13_02220	COG3105	Protein conserved in bacteria
MID13_02225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MID13_02230	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MID13_02235	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MID13_02240	COG0723	plastoquinol--plastocyanin reductase activity
MID13_02245	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MID13_02250	COG2857	Cytochrome c1
MID13_02255	COG0625	glutathione transferase activity
MID13_02260	COG2969	positive regulation of protein catabolic process
MID13_02265	COG2823	Periplasmic or secreted lipoprotein
MID13_02270	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MID13_02285	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MID13_02295	COG0275	rRNA processing
MID13_02300	COG3116	cell division
MID13_02305	COG0768	penicillin binding
MID13_02310	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MID13_02315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MID13_02320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MID13_02325	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MID13_02330	COG0772	Belongs to the SEDS family
MID13_02335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MID13_02340	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MID13_02345	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MID13_02350	COG0849	cell division
MID13_02355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MID13_02360	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MID13_02365	COG0653	protein targeting
MID13_02370	COG0494	nUDIX hydrolase
MID13_02375	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MID13_02380	COG0505	Belongs to the CarA family
MID13_02385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MID13_02390	COG0730	response to heat
MID13_02395	COG0583	DNA-binding transcription factor activity
MID13_02405	COG2860	membrane
MID13_02410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MID13_02420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MID13_02430	COG0493	'glutamate synthase
MID13_02435	COG0067	glutamate synthase
MID13_02435	COG0070	glutamate synthase
MID13_02435	COG0069	glutamate synthase activity
MID13_02445	COG0070	glutamate synthase
MID13_02445	COG0069	glutamate synthase activity
MID13_02445	COG0067	glutamate synthase
MID13_02450	COG1242	4 iron, 4 sulfur cluster binding
MID13_02455	COG5001	Diguanylate cyclase
MID13_02455	COG4251	negative regulation of phosphorylation
MID13_02455	COG3706	GGDEF domain
MID13_02455	COG2203	Gaf domain
MID13_02460	COG0784	Response regulator, receiver
MID13_02460	COG5002	protein histidine kinase activity
MID13_02460	COG2198	Histidine kinase
MID13_02470	COG0745	RESPONSE REGULATOR receiver
MID13_02475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MID13_02490	COG0083	homoserine kinase activity
MID13_02495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MID13_02505	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
MID13_02510	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MID13_02515	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MID13_02530	COG1115	amino acid carrier protein
MID13_02535	COG3022	response to hydroperoxide
MID13_02540	COG0513	Belongs to the DEAD box helicase family
MID13_02545	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MID13_02555	COG0716	FMN binding
MID13_02560	COG4974	Belongs to the 'phage' integrase family
MID13_02565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MID13_02570	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MID13_02580	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MID13_02605	COG0494	nUDIX hydrolase
MID13_02610	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
MID13_02615	COG0730	response to heat
MID13_02620	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MID13_02625	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MID13_02640	COG1283	sodium-dependent phosphate transmembrane transporter activity
MID13_02645	COG0583	DNA-binding transcription factor activity
MID13_02650	COG0640	Transcriptional regulator
MID13_02655	COG0268	Binds directly to 16S ribosomal RNA
MID13_02660	COG0728	peptidoglycan biosynthetic process
MID13_02665	COG0196	riboflavin kinase activity
MID13_02670	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MID13_02680	COG1047	Peptidyl-prolyl cis-trans
MID13_02685	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MID13_02690	COG3279	Response regulator of the LytR AlgR family
MID13_02695	COG3275	phosphorelay sensor kinase activity
MID13_02700	COG1966	Carbon starvation protein
MID13_02710	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MID13_02715	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MID13_02725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MID13_02730	COG1605	Chorismate mutase
MID13_02730	COG0287	Prephenate dehydrogenase
MID13_02735	COG0739	heme binding
MID13_02745	COG0488	(ABC) transporter
MID13_02755	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
MID13_02760	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
MID13_02765	COG5001	Diguanylate cyclase
MID13_02770	COG0077	Prephenate dehydratase
MID13_02770	COG1605	Chorismate mutase
MID13_02775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MID13_02780	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
MID13_02785	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MID13_02790	COG0564	pseudouridine synthase activity
MID13_02835	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
MID13_02845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MID13_02850	COG0826	peptidase U32
MID13_02855	COG2974	May be involved in recombination
MID13_02860	COG0745	RESPONSE REGULATOR receiver
MID13_02865	COG5002	protein histidine kinase activity
MID13_02875	COG0248	Ppx GppA phosphatase
MID13_02880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MID13_02885	COG0573	inorganic phosphate transmembrane transporter activity
MID13_02890	COG0581	inorganic phosphate transmembrane transporter activity
MID13_02895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MID13_02900	COG0704	Plays a role in the regulation of phosphate uptake
MID13_02920	COG3142	Participates in the control of copper homeostasis
MID13_02925	COG0450	alkyl hydroperoxide reductase
MID13_02930	COG0583	DNA-binding transcription factor activity
MID13_02935	COG0517	IMP dehydrogenase activity
MID13_02940	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MID13_02945	COG0343	queuine tRNA-ribosyltransferase activity
MID13_02950	COG1862	Preprotein translocase
MID13_02955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MID13_02960	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MID13_02965	COG0483	inositol monophosphate 1-phosphatase activity
MID13_02970	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
MID13_02975	COG1959	2 iron, 2 sulfur cluster binding
MID13_02980	COG1104	cysteine desulfurase activity
MID13_02985	COG0822	iron-sulfur transferase activity
MID13_02995	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MID13_03000	COG0443	Heat shock 70 kDa protein
MID13_03010	COG2975	iron-sulfur cluster assembly
MID13_03015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MID13_03020	COG0105	UTP biosynthetic process
MID13_03025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MID13_03030	COG1426	Protein conserved in bacteria
MID13_03035	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MID13_03040	COG0124	histidyl-tRNA synthetase
MID13_03045	COG2976	Protein conserved in bacteria
MID13_03050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MID13_03055	COG1160	GTP binding
MID13_03065	COG3706	GGDEF domain
MID13_03075	COG1570	exodeoxyribonuclease VII activity
MID13_03080	COG0516	GMP reductase activity
MID13_03080	COG0517	IMP dehydrogenase activity
MID13_03085	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MID13_03085	COG0519	Catalyzes the synthesis of GMP from XMP
MID13_03095	COG1757	Na H antiporter
MID13_03100	COG1584	GPR1 FUN34 yaaH family protein
MID13_03105	COG1115	amino acid carrier protein
MID13_03110	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
MID13_03115	COG0204	Acyl-transferase
MID13_03125	COG2264	protein methyltransferase activity
MID13_03140	COG4067	protein conserved in archaea
MID13_03140	COG0189	ligase activity
MID13_03155	COG2867	negative regulation of translational initiation
MID13_03160	COG2914	Belongs to the UPF0125 (RnfH) family
MID13_03165	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MID13_03170	COG0497	DNA recombination
MID13_03175	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MID13_03180	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MID13_03190	COG0443	Heat shock 70 kDa protein
MID13_03195	COG0484	heat shock protein binding
MID13_03225	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MID13_03230	COG1253	flavin adenine dinucleotide binding
MID13_03250	COG0047	phosphoribosylformylglycinamidine synthase activity
MID13_03250	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MID13_03260	COG2171	N-acyltransferase activity
MID13_03265	COG0737	Belongs to the 5'-nucleotidase family
MID13_03270	COG2095	MarC family integral membrane protein
MID13_03285	COG3141	response to X-ray
MID13_03300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MID13_03305	COG1074	ATP-dependent DNA helicase activity
MID13_03310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MID13_03320	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MID13_03320	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MID13_03330	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
MID13_03335	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MID13_03340	COG2166	iron-sulfur cluster assembly
MID13_03350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MID13_03355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MID13_03360	COG3248	Nucleoside-binding outer membrane protein
MID13_03375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MID13_03385	COG2813	Specifically methylates the guanine in position
MID13_03390	COG0271	Belongs to the BolA IbaG family
MID13_03395	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MID13_03400	COG1805	sodium ion transport
MID13_03410	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MID13_03415	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
MID13_03420	COG2871	sodium ion transport
MID13_03425	COG1477	protein flavinylation
MID13_03430	COG2991	Protein conserved in bacteria
MID13_03440	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MID13_03445	COG0840	transmembrane signaling receptor activity
MID13_03450	COG0514	ATP-dependent DNA helicase (RecQ)
MID13_03465	COG0733	neurotransmitter:sodium symporter activity
MID13_03470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MID13_03475	COG0321	lipoyl(octanoyl) transferase activity
MID13_03485	COG1686	Belongs to the peptidase S11 family
MID13_03490	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MID13_03495	COG0772	Belongs to the SEDS family
MID13_03500	COG0768	penicillin binding
MID13_03505	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MID13_03510	COG0799	negative regulation of ribosome biogenesis
MID13_03515	COG1466	dna polymerase III delta subunit
MID13_03520	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
MID13_03525	COG0495	leucyl-tRNA aminoacylation
MID13_03530	COG2888	peptidyl-tyrosine sulfation
MID13_03535	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MID13_03540	COG4535	Mg2 and Co2 transporter CorC
MID13_03545	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MID13_03550	COG1702	phosphate starvation-inducible protein PhoH
MID13_03560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MID13_03565	COG2706	6-phosphogluconolactonase activity
MID13_03670	COG0193	aminoacyl-tRNA hydrolase activity
MID13_03675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MID13_03680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MID13_03685	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MID13_03690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MID13_03695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MID13_03700	COG2890	protein-(glutamine-N5) methyltransferase activity
MID13_03705	COG3094	Invasion gene expression up-regulator, SirB
MID13_03710	COG2912	Transglutaminase-like superfamily
MID13_03715	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MID13_03725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MID13_03730	COG1187	pseudouridine synthase activity
MID13_03735	COG2840	Smr protein MutS2
MID13_03775	COG2608	mercury ion transmembrane transporter activity
MID13_03775	COG2217	Heavy metal translocating P-type atpase
MID13_03790	COG1028	Short-chain dehydrogenase reductase Sdr
MID13_03825	COG2986	histidine ammonia-lyase
MID13_03830	COG1216	Glycosyl transferase, family 2
MID13_03850	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID13_03855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MID13_03915	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
MID13_03920	COG0835	chemotaxis
MID13_03920	COG0784	Response regulator, receiver
MID13_03925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
MID13_03930	COG1815	bacterial-type flagellum-dependent cell motility
MID13_03945	COG1749	Flagellar hook protein flgE
MID13_03950	COG4787	bacterial-type flagellum-dependent cell motility
MID13_03960	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
MID13_03965	COG1706	bacterial-type flagellum-dependent cell motility
MID13_03970	COG3951	Flagellar rod assembly protein muramidase FlgJ
MID13_03970	COG1705	Flagellar rod assembly protein muramidase FlgJ
MID13_03990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MID13_03995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MID13_04005	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MID13_04015	COG1516	flagellar protein fliS
MID13_04035	COG1677	Flagellar hook-basal body complex protein FliE
MID13_04045	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MID13_04095	COG1987	bacterial-type flagellum assembly
MID13_04100	COG1684	flagellar biosynthetic protein fliR
MID13_04135	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
MID13_04140	COG2198	Histidine kinase
MID13_04140	COG0784	Response regulator, receiver
MID13_04140	COG0643	Histidine kinase
MID13_04145	COG2201	protein-glutamate methylesterase activity
MID13_04150	COG1192	Involved in chromosome partitioning
MID13_04160	COG0835	chemotaxis
MID13_04170	COG4133	protoheme IX ABC transporter activity
MID13_04175	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MID13_04180	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MID13_04185	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MID13_04190	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
MID13_04195	COG1138	Cytochrome C-type biogenesis protein
MID13_04200	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MID13_04210	COG3088	subunit of a heme lyase
MID13_04210	COG4235	cytochrome complex assembly
MID13_04215	COG2853	Lipoprotein
MID13_04240	COG0183	Belongs to the thiolase family
MID13_04245	COG1250	3-hydroxyacyl-CoA dehydrogenase
MID13_04245	COG1024	Enoyl-CoA hydratase
MID13_04250	COG1025	Belongs to the peptidase M16 family
MID13_04255	COG2062	phosphohistidine phosphatase, SixA
MID13_04260	COG2840	Smr protein MutS2
MID13_04265	COG2890	protein-(glutamine-N5) methyltransferase activity
MID13_04270	COG1280	lysine exporter protein (LysE YggA)
MID13_04275	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MID13_04295	COG1175	transmembrane transport
MID13_04305	COG3842	ATPase activity
MID13_04315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MID13_04320	COG2070	2-Nitropropane dioxygenase
MID13_04320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MID13_04335	COG3321	synthase
MID13_04335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MID13_04350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MID13_04355	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MID13_04360	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MID13_04370	COG2204	response regulator
MID13_04380	COG0544	peptidyl-prolyl cis-trans isomerase activity
MID13_04385	COG0740	serine-type endopeptidase activity
MID13_04390	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MID13_04395	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MID13_04400	COG0776	regulation of translation
MID13_04405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MID13_04425	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MID13_04430	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
MID13_04435	COG0436	Aminotransferase
MID13_04440	COG1169	isochorismate synthase
MID13_04445	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MID13_04450	COG2267	carboxylic ester hydrolase activity
MID13_04470	COG2190	(PTS) system
MID13_04470	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID13_04470	COG1263	PTS System
MID13_04485	COG2855	membrane
MID13_04550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MID13_04565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MID13_04570	COG1522	sequence-specific DNA binding
MID13_04580	COG1946	Acyl-CoA thioesterase
MID13_04585	COG3126	Type III secretion system lipoprotein chaperone (YscW)
MID13_04605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID13_04635	COG0328	RNA-DNA hybrid ribonuclease activity
MID13_04635	COG3341	Caulimovirus viroplasmin
MID13_04645	COG1214	PFAM Peptidase M22, glycoprotease
MID13_04645	COG0456	acetyltransferase
MID13_04650	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MID13_04675	COG0069	glutamate synthase activity
MID13_04695	COG0583	DNA-binding transcription factor activity
MID13_04700	COG0789	Transcriptional regulator
MID13_04705	COG3394	polysaccharide catabolic process
MID13_04710	COG1486	melibiose metabolic process
MID13_04715	COG0583	DNA-binding transcription factor activity
MID13_04740	COG3119	arylsulfatase activity
MID13_04745	COG1609	Transcriptional regulator
MID13_04760	COG2814	Major facilitator Superfamily
MID13_04770	COG1760	l-serine dehydratase
MID13_04775	COG1522	sequence-specific DNA binding
MID13_04780	COG1280	lysine exporter protein (LysE YggA)
MID13_04800	COG0348	domain, Protein
MID13_04805	COG0583	DNA-binding transcription factor activity
MID13_04810	COG1028	Short-chain dehydrogenase reductase Sdr
MID13_04820	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MID13_04825	COG1227	inorganic diphosphatase activity
MID13_04835	COG3153	acetyltransferase
MID13_04870	COG0446	pyridine nucleotide-disulphide oxidoreductase
MID13_04880	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MID13_04895	COG1228	amidohydrolase
MID13_04910	COG3040	lipid binding
MID13_04925	COG0583	DNA-binding transcription factor activity
MID13_04940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MID13_04945	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MID13_04950	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MID13_04955	COG1845	cytochrome c oxidase, subunit III
MID13_04960	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MID13_04975	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MID13_04995	COG0583	DNA-binding transcription factor activity
MID13_05000	COG0346	lactoylglutathione lyase activity
MID13_05005	COG1902	pentaerythritol trinitrate reductase activity
MID13_05035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MID13_05040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MID13_05070	COG0517	IMP dehydrogenase activity
MID13_05070	COG0617	tRNA 3'-terminal CCA addition
MID13_05070	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MID13_05080	COG2217	Heavy metal translocating P-type atpase
MID13_05100	COG0537	adenosine 5'-monophosphoramidase activity
MID13_05125	COG3150	esterase
MID13_05130	COG1252	NADH dehydrogenase
MID13_05145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MID13_05155	COG4591	ABC-type transport system involved in lipoprotein release permease component
MID13_05160	COG1136	(ABC) transporter
MID13_05165	COG4591	ABC-type transport system involved in lipoprotein release permease component
MID13_05175	COG0658	competence protein
MID13_05175	COG2333	competence protein COMEC
MID13_05180	COG1132	(ABC) transporter
MID13_05185	COG1663	tetraacyldisaccharide 4'-kinase activity
MID13_05190	COG2835	tetraacyldisaccharide 4'-kinase activity
MID13_05195	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MID13_05200	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MID13_05205	COG0539	negative regulation of cytoplasmic translation
MID13_05210	COG0776	regulation of translation
MID13_05215	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
MID13_05220	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MID13_05225	COG0284	orotidine-5'-phosphate decarboxylase activity
MID13_05230	COG4174	ABC transporter (Permease)
MID13_05235	COG4239	(ABC) transporter, permease
MID13_05245	COG0444	Belongs to the ABC transporter superfamily
MID13_05250	COG4608	Belongs to the ABC transporter superfamily
MID13_05275	COG0583	DNA-binding transcription factor activity
MID13_05285	COG0686	Belongs to the AlaDH PNT family
MID13_05290	COG1522	sequence-specific DNA binding
MID13_05295	COG1674	ftsk spoiiie
MID13_05300	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MID13_05305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MID13_05310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MID13_05315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MID13_05320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MID13_05325	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MID13_05330	COG0156	8-amino-7-oxononanoate synthase activity
MID13_05350	COG0501	Belongs to the peptidase M48B family
MID13_05355	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MID13_05360	COG2915	High frequency lysogenization protein hflD homolog
MID13_05365	COG0482	sulfurtransferase activity
MID13_05375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MID13_05380	COG2916	Histone family protein nucleoid-structuring protein H-NS
MID13_05385	COG1757	Na H antiporter
MID13_05400	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MID13_05405	COG0131	Imidazoleglycerol-phosphate dehydratase
MID13_05405	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MID13_05410	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MID13_05415	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MID13_05420	COG0107	imidazoleglycerol-phosphate synthase activity
MID13_05425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MID13_05425	COG0140	phosphoribosyl-ATP diphosphatase activity
MID13_05430	COG3012	SEC-C Motif Domain Protein
MID13_05435	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MID13_05440	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MID13_05445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MID13_05450	COG0215	cysteine-tRNA ligase activity
MID13_05460	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MID13_05480	COG2116	formate transmembrane transporter activity
MID13_05485	COG0390	transport system, permease component
MID13_05490	COG4459	periplasmic nitrate reductase
MID13_05495	COG3005	denitrification pathway
MID13_05500	COG0243	molybdopterin cofactor binding
MID13_05510	COG1227	inorganic diphosphatase activity
MID13_05525	COG4172	Belongs to the ABC transporter superfamily
MID13_05540	COG4168	peptide transport system, permease
MID13_05545	COG4166	transmembrane transport
MID13_05550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
MID13_05555	COG1842	Phage shock protein A
MID13_05565	COG1983	PspC domain protein
MID13_05570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MID13_05585	COG2818	Glycosylase
MID13_05600	COG0626	cystathionine gamma-synthase activity
MID13_05610	COG0733	neurotransmitter:sodium symporter activity
MID13_05620	COG0564	pseudouridine synthase activity
MID13_05630	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MID13_05635	COG4136	ATPase activity
MID13_05640	COG4135	transport system, permease component
MID13_05645	COG4134	Bacterial extracellular solute-binding protein
MID13_05655	COG3313	Fe-S protein
MID13_05675	COG0513	Belongs to the DEAD box helicase family
MID13_05680	COG1280	lysine exporter protein (LysE YggA)
MID13_05690	COG2866	Carboxypeptidase
MID13_05720	COG4176	ABC-type proline glycine betaine transport system permease component
MID13_05725	COG2113	Glycine betaine
MID13_05735	COG0583	DNA-binding transcription factor activity
MID13_05770	COG1280	lysine exporter protein (LysE YggA)
MID13_05775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MID13_05840	COG3547	Transposase (IS116 IS110 IS902 family)
MID13_05880	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MID13_05890	COG0586	Pfam SNARE associated Golgi protein
MID13_05905	COG0848	biopolymer transport protein
MID13_05910	COG0811	peptide transport
MID13_05915	COG0811	peptide transport
MID13_05925	COG4771	TonB-dependent receptor
MID13_05930	COG4178	(ABC) transporter
MID13_05935	COG0612	Peptidase, M16
MID13_05945	COG2205	protein histidine kinase activity
MID13_05960	COG1061	Type III restriction enzyme res subunit
MID13_05970	COG2814	Major facilitator Superfamily
MID13_05980	COG0702	epimerase
MID13_05985	COG1858	cytochrome C peroxidase
MID13_05990	COG0534	Mate efflux family protein
MID13_06010	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MID13_06040	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MID13_06045	COG2985	domain, Protein
MID13_06045	COG3273	potassium ion transport
MID13_06050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MID13_06060	COG1737	Transcriptional regulator
MID13_06065	COG0076	glutamate decarboxylase activity
MID13_06075	COG2431	L-lysine efflux transmembrane transporter activity
MID13_06085	COG3070	regulator of competence-specific genes
MID13_06095	COG2204	response regulator
MID13_06100	COG4191	Histidine kinase
MID13_06110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MID13_06130	COG2258	MOSC domain
MID13_06150	COG1448	Aminotransferase
MID13_06155	COG2770	Histidine kinase
MID13_06155	COG3437	response regulator, receiver
MID13_06165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MID13_06185	COG0017	Asparaginyl-tRNA synthetase
MID13_06190	COG0659	secondary active sulfate transmembrane transporter activity
MID13_06195	COG0840	transmembrane signaling receptor activity
MID13_06205	COG0814	amino acid
MID13_06210	COG1760	l-serine dehydratase
MID13_06215	COG0814	amino acid
MID13_06220	COG0494	nUDIX hydrolase
MID13_06250	COG3106	COG3106 Predicted ATPase
MID13_06265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MID13_06275	COG2199	diguanylate cyclase activity
MID13_06275	COG2203	Gaf domain
MID13_06285	COG0443	Heat shock 70 kDa protein
MID13_06300	COG3706	GGDEF domain
MID13_06320	COG3710	Transcriptional regulator
MID13_06350	COG1643	Atp-dependent helicase
MID13_06400	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MID13_06405	COG0072	phenylalanine-tRNA ligase activity
MID13_06405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MID13_06425	COG0596	Alpha beta hydrolase
MID13_06500	COG1522	sequence-specific DNA binding
MID13_06505	COG2873	o-acetylhomoserine
MID13_06525	COG1289	transmembrane transporter activity
MID13_06555	COG2205	protein histidine kinase activity
MID13_06570	COG1342	Belongs to the UPF0251 family
MID13_06580	COG2207	Transcriptional regulator
MID13_06585	COG0346	lactoylglutathione lyase activity
MID13_06610	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
MID13_06625	COG0776	regulation of translation
MID13_06645	COG0840	transmembrane signaling receptor activity
MID13_06655	COG0583	DNA-binding transcription factor activity
MID13_06665	COG2175	clavaminate synthase activity
MID13_06680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MID13_06695	COG1028	Short-chain dehydrogenase reductase Sdr
MID13_06700	COG0776	regulation of translation
MID13_06730	COG0500	methyltransferase
MID13_06735	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MID13_06740	COG0295	cytidine deaminase activity
MID13_06745	COG1346	cytolysis
MID13_06755	COG2925	Exonuclease
MID13_06800	COG3568	Endonuclease Exonuclease Phosphatase
MID13_06830	COG4989	oxidoreductase activity
MID13_06840	COG1823	symporter activity
MID13_06845	COG0702	epimerase
MID13_06850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MID13_06855	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MID13_06860	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
MID13_06870	COG0406	alpha-ribazole phosphatase activity
MID13_06880	COG2988	succinylglutamate desuccinylase activity
MID13_06885	COG4139	cobalamin transport
MID13_06890	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
MID13_06900	COG3397	chitin binding
MID13_06915	COG1247	-acetyltransferase
MID13_06935	COG2814	Major facilitator Superfamily
MID13_06940	COG0583	DNA-binding transcription factor activity
MID13_06950	COG1451	nucleotide metabolic process
MID13_06960	COG3063	Type IV pilus biogenesis stability protein PilW
MID13_06965	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
MID13_06980	COG2195	Cleaves the N-terminal amino acid of tripeptides
MID13_07010	COG0582	viral genome integration into host DNA
MID13_07025	COG4983	Phage plasmid primase, P4 family domain protein
MID13_07040	COG0582	viral genome integration into host DNA
MID13_07055	COG2003	Belongs to the UPF0758 family
MID13_07065	COG0457	Tetratricopeptide repeat
MID13_07070	COG2814	Major facilitator Superfamily
MID13_07070	COG0477	Major facilitator Superfamily
MID13_07075	COG1940	carbohydrate kinase activity
MID13_07160	COG0583	DNA-binding transcription factor activity
MID13_07180	COG4964	Belongs to the GSP D family
MID13_07190	COG0455	bacterial-type flagellum organization
MID13_07245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MID13_07250	COG0583	DNA-binding transcription factor activity
MID13_07265	COG0840	transmembrane signaling receptor activity
MID13_07275	COG3469	chitinase activity
MID13_07285	COG4771	TonB-dependent receptor
MID13_07295	COG2199	diguanylate cyclase activity
MID13_07295	COG2203	Gaf domain
MID13_07300	COG0454	-acetyltransferase
MID13_07305	COG1472	Belongs to the glycosyl hydrolase 3 family
MID13_07310	COG0420	3'-5' exonuclease activity
MID13_07315	COG0419	ATPase involved in DNA repair
MID13_07335	COG3046	protein related to deoxyribodipyrimidine photolyase
MID13_07340	COG0415	Belongs to the DNA photolyase family
MID13_07345	COG0589	response to stress
MID13_07365	COG1120	ATPase activity
MID13_07370	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MID13_07380	COG4615	Cyclic peptide transporter
MID13_07400	COG4774	siderophore transport
MID13_07420	COG2271	Major facilitator Superfamily
MID13_07425	COG0584	glycerophosphoryl diester phosphodiesterase
MID13_07435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MID13_07455	COG0494	nUDIX hydrolase
MID13_07470	COG1187	pseudouridine synthase activity
MID13_07480	COG0110	maltose O-acetyltransferase activity
MID13_07550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MID13_07570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MID13_07570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MID13_07575	COG1051	belongs to the nudix hydrolase family
MID13_07585	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MID13_07620	COG0346	lactoylglutathione lyase activity
MID13_07645	COG1765	OsmC-like protein
MID13_07660	COG1619	proteins homologs of microcin C7 resistance protein MccF
MID13_07685	COG0653	protein targeting
MID13_07690	COG0546	phosphoglycolate phosphatase activity
MID13_07700	COG1028	Short-chain dehydrogenase reductase Sdr
MID13_07735	COG0786	glutamate:sodium symporter activity
MID13_07750	COG0826	peptidase U32
MID13_07765	COG1126	abc transporter atp-binding protein
MID13_07770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID13_07775	COG4215	(ABC) transporter
MID13_07780	COG4160	amino acid transport
MID13_07785	COG1280	lysine exporter protein (LysE YggA)
MID13_07895	COG0583	DNA-binding transcription factor activity
MID13_07900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MID13_07905	COG1215	transferase activity, transferring glycosyl groups
MID13_07945	COG0438	transferase activity, transferring glycosyl groups
MID13_07955	COG2204	response regulator
MID13_07965	COG3448	diguanylate cyclase activity
MID13_07965	COG4175	Glycine betaine
MID13_07970	COG4176	ABC-type proline glycine betaine transport system permease component
MID13_07980	COG4999	Histidine kinase
MID13_07980	COG2205	protein histidine kinase activity
MID13_07980	COG3437	response regulator, receiver
MID13_07980	COG3850	Histidine kinase
MID13_08010	COG1793	dna ligase
MID13_08015	COG0534	Mate efflux family protein
MID13_08020	COG0307	riboflavin synthase, alpha
MID13_08030	COG3001	Fructosamine kinase
MID13_08040	COG0791	NLP P60 protein
MID13_08045	COG0840	transmembrane signaling receptor activity
MID13_08045	COG3290	protein histidine kinase activity
MID13_08055	COG3148	PFAM DTW domain containing protein
MID13_08060	COG1940	carbohydrate kinase activity
MID13_08070	COG0303	'Molybdopterin
MID13_08075	COG0746	molybdenum cofactor guanylyltransferase activity
MID13_08080	COG3842	ATPase activity
MID13_08085	COG4662	Binding-protein-dependent transport system inner membrane component
MID13_08095	COG2204	response regulator
MID13_08100	COG4191	Histidine kinase
MID13_08120	COG0488	(ABC) transporter
MID13_08135	COG1294	oxidase, subunit
MID13_08140	COG1271	oxidase subunit
MID13_08155	COG3220	belongs to the UPF0276 family
MID13_08170	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MID13_08190	COG3381	protein complex oligomerization
MID13_08200	COG0243	molybdopterin cofactor binding
MID13_08200	COG3383	formate dehydrogenase (NAD+) activity
MID13_08205	COG0437	4 iron, 4 sulfur cluster binding
MID13_08225	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MID13_08235	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MID13_08245	COG1177	transmembrane transport
MID13_08255	COG3842	ATPase activity
MID13_08275	COG0037	tRNA processing
MID13_08280	COG0589	response to stress
MID13_08285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MID13_08300	COG2217	Heavy metal translocating P-type atpase
MID13_08310	COG2010	Cytochrome c
MID13_08325	COG3278	Belongs to the heme-copper respiratory oxidase family
MID13_08340	COG0784	Response regulator, receiver
MID13_08340	COG2205	protein histidine kinase activity
MID13_08365	COG3120	sequence-specific DNA binding
MID13_08370	COG1067	ATP-dependent peptidase activity
MID13_08390	COG0488	(ABC) transporter
MID13_08400	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MID13_08400	COG0116	Belongs to the methyltransferase superfamily
MID13_08410	COG0167	dihydroorotate dehydrogenase activity
MID13_08415	COG2902	Dehydrogenase
MID13_08425	COG0308	aminopeptidase N
MID13_08440	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
MID13_08445	COG1956	GAF domain-containing protein
MID13_08450	COG1132	(ABC) transporter
MID13_08455	COG2995	paraquat-inducible protein a
MID13_08460	COG3008	intermembrane lipid transfer
MID13_08465	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
MID13_08465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MID13_08470	COG2996	Protein conserved in bacteria
MID13_08485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MID13_08485	COG0574	Belongs to the PEP-utilizing enzyme family
MID13_08490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MID13_08495	COG1666	GTP binding
MID13_08505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID13_08510	COG4597	amino acid ABC transporter
MID13_08515	COG0765	amino acid transport
MID13_08520	COG1126	abc transporter atp-binding protein
MID13_08525	COG0670	Belongs to the BI1 family
MID13_08530	COG2920	part of a sulfur-relay system
MID13_08535	COG1254	Belongs to the acylphosphatase family
MID13_08540	COG0840	transmembrane signaling receptor activity
MID13_08545	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
MID13_08580	COG2885	chlorophyll binding
MID13_08595	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MID13_08600	COG0602	queuosine metabolic process
MID13_08605	COG0561	phosphatase activity
MID13_08635	COG2828	Protein conserved in bacteria
MID13_08640	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MID13_08645	COG0372	Belongs to the citrate synthase family
MID13_08650	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MID13_08660	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MID13_08775	COG3437	response regulator, receiver
MID13_08810	COG4628	conserved protein (DUF2132)
MID13_08815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MID13_08820	COG1566	PFAM secretion protein HlyD family protein
MID13_08830	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MID13_08835	COG0363	glucosamine-6-phosphate deaminase activity
MID13_08840	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MID13_08845	COG4565	transcriptional regulatory protein
MID13_08850	COG3290	protein histidine kinase activity
MID13_08865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MID13_08880	COG1115	amino acid carrier protein
MID13_08890	COG1115	amino acid carrier protein
MID13_08910	COG1280	lysine exporter protein (LysE YggA)
MID13_08930	COG0730	response to heat
MID13_08975	COG1247	-acetyltransferase
MID13_09005	COG4191	Histidine kinase
MID13_09005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID13_09010	COG0471	metal ion transport
MID13_09015	COG1335	isochorismatase
MID13_09050	COG0741	lytic transglycosylase activity
MID13_09050	COG0739	heme binding
MID13_09050	COG1196	nuclear chromosome segregation
MID13_09080	COG3033	Beta-eliminating lyase
MID13_09105	COG0840	transmembrane signaling receptor activity
MID13_09110	COG2186	Transcriptional regulator
MID13_09115	COG0800	Aldolase
MID13_09130	COG0010	Belongs to the arginase family
MID13_09135	COG1166	arginine decarboxylase activity
MID13_09140	COG2226	methyltransferase
MID13_09150	COG1309	transcriptional regulator
MID13_09155	COG0488	(ABC) transporter
MID13_09170	COG3097	Belongs to the UPF0267 family
MID13_09175	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MID13_09180	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MID13_09215	COG4326	sporulation control protein
MID13_09225	COG1228	amidohydrolase
MID13_09230	COG0010	Belongs to the arginase family
MID13_09235	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MID13_09240	COG2986	histidine ammonia-lyase
MID13_09255	COG0247	lactate metabolic process
MID13_09255	COG0277	FAD linked oxidase domain protein
MID13_09290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MID13_09300	COG1643	Atp-dependent helicase
MID13_09305	COG0281	malic enzyme
MID13_09310	COG2949	membrane
MID13_09315	COG0471	metal ion transport
MID13_09335	COG2199	diguanylate cyclase activity
MID13_09350	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MID13_09390	COG0492	ferredoxin-NADP+ reductase activity
MID13_09395	COG4988	ABC transporter
MID13_09400	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MID13_09410	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MID13_09415	COG1780	Probably involved in ribonucleotide reductase function
MID13_09425	COG0316	Belongs to the HesB IscA family
MID13_09430	COG0719	Fe-S assembly protein
MID13_09435	COG0396	ATPase activity
MID13_09440	COG0719	Fe-S assembly protein
MID13_09445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MID13_09450	COG2166	iron-sulfur cluster assembly
MID13_09455	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
MID13_09460	COG0840	transmembrane signaling receptor activity
MID13_09465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MID13_09470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MID13_09495	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MID13_09510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MID13_09515	COG3108	Peptidase M15
MID13_09520	COG2989	Protein conserved in bacteria
MID13_09545	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MID13_09555	COG3088	subunit of a heme lyase
MID13_09555	COG4235	cytochrome complex assembly
MID13_09565	COG1138	Cytochrome C-type biogenesis protein
MID13_09570	COG3301	Polysulphide reductase, NrfD
MID13_09575	COG0437	4 iron, 4 sulfur cluster binding
MID13_09580	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
MID13_09590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MID13_09605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MID13_09610	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MID13_09615	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MID13_09635	COG0243	molybdopterin cofactor binding
MID13_09640	COG0437	4 iron, 4 sulfur cluster binding
MID13_09645	COG3302	dmso reductase anchor subunit
MID13_09675	COG0019	diaminopimelate decarboxylase activity
MID13_09715	COG0322	excinuclease ABC activity
MID13_09720	COG2197	response regulator
MID13_09725	COG0417	DNA replication proofreading
MID13_09735	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MID13_09750	COG1187	pseudouridine synthase activity
MID13_09755	COG0009	L-threonylcarbamoyladenylate synthase
MID13_09760	COG0613	PHP domain protein
MID13_09770	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MID13_09775	COG0512	Glutamine amidotransferase of anthranilate synthase
MID13_09780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MID13_09785	COG0135	phosphoribosylanthranilate isomerase activity
MID13_09785	COG0134	indole-3-glycerol-phosphate synthase activity
MID13_09790	COG0133	tryptophan synthase activity
MID13_09795	COG0159	tryptophan synthase activity
MID13_09800	COG0330	HflC and HflK could
MID13_09810	COG1301	dicarboxylic acid transport
MID13_09830	COG0840	transmembrane signaling receptor activity
MID13_09835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID13_09855	COG2917	probably involved in intracellular septation
MID13_09860	COG1607	acyl-coa hydrolase
MID13_09865	COG2350	Protein conserved in bacteria
MID13_09875	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MID13_09895	COG1032	radical SAM domain protein
MID13_09905	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MID13_09910	COG0463	Glycosyl transferase, family 2
MID13_09915	COG0745	RESPONSE REGULATOR receiver
MID13_09935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MID13_09940	COG0583	DNA-binding transcription factor activity
MID13_09950	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MID13_09975	COG0786	glutamate:sodium symporter activity
MID13_09990	COG5002	protein histidine kinase activity
MID13_09990	COG0784	Response regulator, receiver
MID13_10005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MID13_10010	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
MID13_10015	COG2885	chlorophyll binding
MID13_10020	COG0823	Involved in the tonB-independent uptake of proteins
MID13_10035	COG0811	peptide transport
MID13_10040	COG0824	Thioesterase
MID13_10050	COG4890	Cyd operon protein YbgT
MID13_10055	COG1294	oxidase, subunit
MID13_10060	COG1271	oxidase subunit
MID13_10065	COG2255	four-way junction helicase activity
MID13_10070	COG0632	four-way junction helicase activity
MID13_10075	COG0840	transmembrane signaling receptor activity
MID13_10080	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MID13_10085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MID13_10090	COG1801	Protein of unknown function DUF72
MID13_10095	COG4106	trans-aconitate 2-methyltransferase activity
MID13_10100	COG0500	methyltransferase
MID13_10105	COG4067	protein conserved in archaea
MID13_10105	COG0189	ligase activity
MID13_10120	COG3383	formate dehydrogenase (NAD+) activity
MID13_10125	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
MID13_10130	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
MID13_10135	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
MID13_10140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MID13_10145	COG1434	Gram-negative-bacterium-type cell wall biogenesis
MID13_10150	COG0745	RESPONSE REGULATOR receiver
MID13_10155	COG3381	protein complex oligomerization
MID13_10160	COG1609	Transcriptional regulator
MID13_10165	COG3070	regulator of competence-specific genes
MID13_10185	COG0297	glycogen (starch) synthase activity
MID13_10190	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MID13_10195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MID13_10205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MID13_10215	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MID13_10220	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MID13_10225	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MID13_10230	COG0542	response to heat
MID13_10235	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MID13_10240	COG1278	Cold shock
MID13_10250	COG1187	pseudouridine synthase activity
MID13_10260	COG1199	ATP-dependent helicase activity
MID13_10280	COG2850	peptidyl-arginine hydroxylation
MID13_10290	COG2814	Major facilitator Superfamily
MID13_10295	COG1770	oligopeptidase
MID13_10300	COG0708	Exodeoxyribonuclease III
MID13_10310	COG4160	amino acid transport
MID13_10340	COG1882	Formate acetyltransferase
MID13_10350	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MID13_10355	COG3013	Belongs to the UPF0304 family
MID13_10360	COG3713	MltA-interacting MipA family protein
MID13_10365	COG2766	serine protein kinase
MID13_10370	COG2718	Belongs to the UPF0229 family
MID13_10375	COG2719	SpoVR family
MID13_10380	COG0616	signal peptide processing
MID13_10385	COG1028	Short-chain dehydrogenase reductase Sdr
MID13_10390	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MID13_10405	COG0784	Response regulator, receiver
MID13_10405	COG0835	chemotaxis
MID13_10410	COG1940	carbohydrate kinase activity
MID13_10415	COG0469	pyruvate kinase activity
MID13_10420	COG4667	esterase of the alpha-beta hydrolase superfamily
MID13_10445	COG0084	hydrolase, TatD family'
MID13_10450	COG0470	DNA polymerase III
MID13_10460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MID13_10465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MID13_10490	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MID13_10495	COG0416	fatty acid biosynthetic process
MID13_10500	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MID13_10505	COG1399	metal-binding, possibly nucleic acid-binding protein
MID13_10515	COG0564	pseudouridine synthase activity
MID13_10520	COG1530	ribonuclease E activity
MID13_10525	COG0659	secondary active sulfate transmembrane transporter activity
MID13_10530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MID13_10535	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
MID13_10540	COG2982	Protein involved in outer membrane biogenesis
MID13_10545	COG0572	uridine kinase
MID13_10550	COG0489	protein tyrosine kinase activity
MID13_10555	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MID13_10555	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MID13_10565	COG2186	Transcriptional regulator
MID13_10570	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MID13_10575	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
MID13_10580	COG0653	protein targeting
MID13_10585	COG2165	general secretion pathway protein
MID13_10590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MID13_10595	COG3706	GGDEF domain
MID13_10600	COG0366	Alpha amylase catalytic
MID13_10610	COG3092	negative regulation of chromosome organization
MID13_10615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MID13_10620	COG0857	belongs to the CobB CobQ family
MID13_10620	COG0280	phosphate acetyltransferase
MID13_10625	COG0435	Glutathione S-transferase
MID13_10635	COG0444	Belongs to the ABC transporter superfamily
MID13_10640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MID13_10645	COG0601	transmembrane transport
MID13_10655	COG0314	molybdopterin synthase activity
MID13_10660	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MID13_10665	COG0315	cyclic pyranopterin monophosphate synthase activity
MID13_10670	COG0521	Mo-molybdopterin cofactor biosynthetic process
MID13_10675	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MID13_10680	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MID13_10685	COG2198	Histidine kinase
MID13_10690	COG2204	response regulator
MID13_10695	COG0556	nucleotide-excision repair
MID13_10705	COG4657	Part of a membrane complex involved in electron transport
MID13_10710	COG2878	Part of a membrane complex involved in electron transport
MID13_10715	COG4656	Part of a membrane complex involved in electron transport
MID13_10720	COG4658	electron transport chain
MID13_10725	COG4659	FMN binding
MID13_10730	COG4660	Part of a membrane complex involved in electron transport
MID13_10735	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MID13_10740	COG0346	lactoylglutathione lyase activity
MID13_10750	COG2885	chlorophyll binding
MID13_10760	COG2056	Na+-H+ antiporter family
MID13_10780	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MID13_10800	COG1454	alcohol dehydrogenase
MID13_10800	COG1012	belongs to the aldehyde dehydrogenase family
MID13_10805	COG2095	MarC family integral membrane protein
MID13_10810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MID13_10820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MID13_10825	COG1757	Na H antiporter
MID13_10840	COG3081	Nucleoid-associated protein
MID13_10845	COG3082	Protein of unknown function (DUF1414)
MID13_10850	COG3083	sulfuric ester hydrolase activity
MID13_10865	COG1959	2 iron, 2 sulfur cluster binding
MID13_10875	COG0123	including yeast histone deacetylase and acetoin utilization protein
MID13_10890	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MID13_10895	COG0778	Nitroreductase
MID13_10900	COG0446	pyridine nucleotide-disulphide oxidoreductase
MID13_10900	COG1902	pentaerythritol trinitrate reductase activity
MID13_10905	COG0616	signal peptide processing
MID13_10910	COG0252	asparaginase activity
MID13_10915	COG3139	Protein of unknown function (DUF1315)
MID13_10925	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MID13_10945	COG2226	methyltransferase
MID13_10965	COG1785	Belongs to the alkaline phosphatase family
MID13_10970	COG2983	Belongs to the UPF0260 family
MID13_10985	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MID13_10990	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MID13_10995	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MID13_11000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MID13_11005	COG2832	Protein of unknown function (DUF454)
MID13_11015	COG0745	RESPONSE REGULATOR receiver
MID13_11020	COG0583	DNA-binding transcription factor activity
MID13_11025	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MID13_11030	COG1286	toxin biosynthetic process
MID13_11035	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
MID13_11040	COG0285	dihydrofolate synthase activity
MID13_11045	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MID13_11050	COG0101	tRNA pseudouridine synthase activity
MID13_11060	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MID13_11065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MID13_11070	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MID13_11090	COG3101	peptidyl-lysine hydroxylation
MID13_11095	COG2860	membrane
MID13_11100	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MID13_11110	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MID13_11120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MID13_11125	COG0583	DNA-binding transcription factor activity
MID13_11130	COG2951	lytic endotransglycosylase activity
MID13_11135	COG3100	YcgL domain-containing protein
MID13_11140	COG0850	regulation of cytokinetic process
MID13_11145	COG2894	cell division
MID13_11150	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MID13_11155	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
MID13_11160	COG0318	PFAM AMP-dependent synthetase and ligase
MID13_11165	COG0596	Alpha beta hydrolase
MID13_11180	COG1214	PFAM Peptidase M22, glycoprotease
MID13_11185	COG1199	ATP-dependent helicase activity
MID13_11195	COG0788	formyltetrahydrofolate deformylase activity
MID13_11200	COG3102	Protein conserved in bacteria
MID13_11205	COG0018	arginyl-trna synthetase
MID13_11230	COG1918	ferrous iron import across plasma membrane
MID13_11240	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
MID13_11245	COG1121	(ABC) transporter
MID13_11250	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MID13_11260	COG0045	succinate-CoA ligase (ADP-forming) activity
MID13_11265	COG0508	dehydrogenase complex catalyzes the overall conversion of
MID13_11270	COG0567	Dehydrogenase, E1 component
MID13_11275	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MID13_11280	COG1053	succinate dehydrogenase
MID13_11285	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MID13_11300	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MID13_11310	COG0033	Phosphoglucomutase
MID13_11315	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
MID13_11320	COG0596	Alpha beta hydrolase
MID13_11350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MID13_11355	COG2190	(PTS) system
MID13_11355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID13_11355	COG1263	PTS System
MID13_11360	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
MID13_11365	COG1940	carbohydrate kinase activity
MID13_11365	COG1846	Transcriptional regulator
MID13_11370	COG4651	solute:proton antiporter activity
MID13_11370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MID13_11375	COG0367	asparagine synthase
MID13_11385	COG3104	oligopeptide transport
MID13_11390	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MID13_11395	COG0563	adenylate kinase activity
MID13_11400	COG0326	Molecular chaperone. Has ATPase activity
MID13_11405	COG3710	Transcriptional regulator
MID13_11425	COG0622	Phosphoesterase
MID13_11450	COG1090	epimerase
MID13_11455	COG0300	oxidoreductase activity
MID13_11460	COG3118	belongs to the thioredoxin family
MID13_11465	COG0330	HflC and HflK could
MID13_11475	COG0789	Transcriptional regulator
MID13_11500	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MID13_11505	COG3115	cell septum assembly
MID13_11510	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
MID13_11520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID13_11530	COG2190	(PTS) system
MID13_11535	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MID13_11540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MID13_11545	COG2837	iron assimilation
MID13_11570	COG1393	Belongs to the ArsC family
MID13_11575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MID13_11590	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MID13_11595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MID13_11600	COG2716	regulation of RNA biosynthetic process
MID13_11605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MID13_11620	COG4783	chaperone-mediated protein folding
MID13_11625	COG1393	Belongs to the ArsC family
MID13_11655	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MID13_11660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MID13_11665	COG0121	glutamine amidotransferase
MID13_11675	COG1960	acyl-CoA dehydrogenase activity
MID13_11685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MID13_11690	COG0328	RNA-DNA hybrid ribonuclease activity
MID13_11695	COG2226	methyltransferase
MID13_11700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MID13_11705	COG0741	lytic transglycosylase activity
MID13_11705	COG1388	LysM domain
MID13_11715	COG3021	interspecies interaction between organisms
MID13_11720	COG0347	Belongs to the P(II) protein family
MID13_11730	COG0037	tRNA processing
MID13_11735	COG0825	malonyl-CoA metabolic process
MID13_11740	COG0587	DNA-directed DNA polymerase activity
MID13_11745	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MID13_11755	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MID13_11760	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MID13_11765	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MID13_11770	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
MID13_11780	COG0750	zinc metalloprotease
MID13_11790	COG0575	Belongs to the CDS family
MID13_11795	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MID13_11800	COG0233	cytoplasmic translational termination
MID13_11805	COG0528	UMP kinase activity
MID13_11815	COG0052	Belongs to the universal ribosomal protein uS2 family
MID13_11820	COG0024	Methionine aminopeptidase
MID13_11825	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MID13_11835	COG0564	pseudouridine synthase activity
MID13_11840	COG3098	single-species biofilm formation
MID13_11865	COG1671	Belongs to the UPF0178 family
MID13_11875	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
MID13_11885	COG0254	rRNA binding
MID13_11890	COG1720	tRNA m6t6A37 methyltransferase activity
MID13_11895	COG0442	prolyl-tRNA aminoacylation
MID13_11945	COG0366	Alpha amylase catalytic
MID13_11950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID13_11950	COG1263	PTS System
MID13_11955	COG1609	Transcriptional regulator
MID13_11965	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MID13_11970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MID13_11975	COG2011	ABC-type metal ion transport system permease component
MID13_11980	COG1464	Belongs to the NlpA lipoprotein family
MID13_11985	COG4580	involved in the transport of maltose and maltodextrins
MID13_11990	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
MID13_12000	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MID13_12000	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MID13_12015	COG1611	Belongs to the LOG family
MID13_12020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MID13_12030	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
MID13_12035	COG2363	Small membrane protein
MID13_12045	COG0583	DNA-binding transcription factor activity
MID13_12050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MID13_12050	COG0301	tRNA thio-modification
MID13_12065	COG1722	exodeoxyribonuclease VII activity
MID13_12070	COG0142	geranyltranstransferase activity
MID13_12075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MID13_12085	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MID13_12090	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MID13_12095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MID13_12115	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MID13_12115	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MID13_12120	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MID13_12125	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MID13_12140	COG1073	alpha beta
MID13_12145	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
MID13_12150	COG2252	PERMEase
MID13_12155	COG2195	Cleaves the N-terminal amino acid of tripeptides
MID13_12175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MID13_12190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MID13_12195	COG1609	Transcriptional regulator
MID13_12200	COG2017	converts alpha-aldose to the beta-anomer
MID13_12215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MID13_12220	COG1609	Transcriptional regulator
MID13_12225	COG3250	beta-galactosidase activity
MID13_12230	COG2731	YhcH YjgK YiaL family protein
MID13_12235	COG0531	amino acid
MID13_12240	COG0531	amino acid
MID13_12250	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
MID13_12250	COG3408	Glycogen debranching enzyme
MID13_12265	COG0583	DNA-binding transcription factor activity
MID13_12270	COG2059	Chromate
MID13_12330	COG4964	Belongs to the GSP D family
MID13_12360	COG1022	Amp-dependent synthetase and ligase
MID13_12370	COG0583	DNA-binding transcription factor activity
MID13_12375	COG4628	conserved protein (DUF2132)
MID13_12380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MID13_12385	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MID13_12395	COG0560	Phosphoserine phosphatase
MID13_12405	COG0813	purine-nucleoside phosphorylase activity
MID13_12415	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
MID13_12420	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MID13_12425	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MID13_12430	COG0084	hydrolase, TatD family'
MID13_12440	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MID13_12460	COG3154	lipid carrier protein
MID13_12470	COG0826	peptidase U32
MID13_12475	COG0826	peptidase U32
MID13_12480	COG0534	Mate efflux family protein
MID13_12495	COG1185	polyribonucleotide nucleotidyltransferase activity
MID13_12500	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MID13_12505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MID13_12510	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MID13_12515	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MID13_12520	COG0195	Participates in both transcription termination and antitermination
MID13_12525	COG0779	Required for maturation of 30S ribosomal subunits
MID13_12540	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MID13_12545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MID13_12550	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MID13_12555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MID13_12560	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MID13_12565	COG1534	Rna-binding protein
MID13_12570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MID13_12580	COG2027	D-alanyl-D-alanine carboxypeptidase
MID13_12585	COG2239	Acts as a magnesium transporter
MID13_12590	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MID13_12595	COG0739	heme binding
MID13_12610	COG0316	Belongs to the HesB IscA family
MID13_12615	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MID13_12620	COG0628	permease
MID13_12625	COG2813	Specifically methylates the guanine in position
MID13_12635	COG0747	negative chemotaxis
MID13_12645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MID13_12650	COG0444	Belongs to the ABC transporter superfamily
MID13_12655	COG4608	Belongs to the ABC transporter superfamily
MID13_12665	COG2971	BadF BadG BcrA BcrD
MID13_12680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MID13_12685	COG3842	ATPase activity
MID13_12695	COG1840	ABC-type Fe3 transport system, periplasmic component
MID13_12700	COG0004	ammonium transporteR
MID13_12715	COG1049	propionate catabolic process, 2-methylcitrate cycle
MID13_12720	COG1752	Esterase of the alpha-beta hydrolase superfamily
MID13_12725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MID13_12730	COG1643	Atp-dependent helicase
MID13_12735	COG1489	DNA binding
MID13_12745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MID13_12755	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MID13_12760	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MID13_12765	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MID13_12770	COG0842	Transport permease protein
MID13_12775	COG1131	(ABC) transporter
MID13_12780	COG0659	secondary active sulfate transmembrane transporter activity
MID13_12785	COG0288	reversible hydration of carbon dioxide
MID13_12800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MID13_12805	COG0508	dehydrogenase complex catalyzes the overall conversion of
MID13_12810	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
MID13_12815	COG2186	Transcriptional regulator
MID13_12825	COG0157	Belongs to the NadC ModD family
MID13_12835	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MID13_12840	COG1459	type II secretion system
MID13_12850	COG0237	dephospho-CoA kinase activity
MID13_12855	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MID13_12865	COG0335	large ribosomal subunit rRNA binding
MID13_12870	COG0336	Belongs to the RNA methyltransferase TrmD family
MID13_12875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MID13_12885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MID13_12890	COG4137	Cytochrome C assembly protein
MID13_12895	COG4536	flavin adenine dinucleotide binding
MID13_12900	COG1854	S-ribosylhomocysteine lyase activity
MID13_12915	COG0612	Peptidase, M16
MID13_12920	COG1238	metal cluster binding
MID13_12930	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
MID13_12935	COG0511	ligase activity, forming carbon-carbon bonds
MID13_12935	COG5016	pyruvate
MID13_12940	COG3630	sodium ion export across plasma membrane
MID13_13000	COG0527	aspartate kinase activity
MID13_13010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MID13_13015	COG1546	Belongs to the CinA family
MID13_13020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MID13_13025	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MID13_13035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MID13_13040	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MID13_13045	COG0585	pseudouridine synthase activity
MID13_13055	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MID13_13060	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MID13_13065	COG0148	phosphopyruvate hydratase activity
MID13_13070	COG0504	CTP synthase activity
MID13_13075	COG3956	TIGRFAM MazG family protein
MID13_13085	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MID13_13090	COG3850	Histidine kinase
MID13_13090	COG3437	response regulator, receiver
MID13_13090	COG4999	Histidine kinase
MID13_13090	COG2205	protein histidine kinase activity
MID13_13095	COG0736	holo-[acyl-carrier-protein] synthase activity
MID13_13100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MID13_13105	COG1381	Involved in DNA repair and RecF pathway recombination
MID13_13110	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MID13_13115	COG0571	ribonuclease III activity
MID13_13125	COG0481	GTPase activity
MID13_13145	COG1595	DNA-templated transcription, initiation
MID13_13150	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MID13_13155	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MID13_13160	COG0354	folic acid binding
MID13_13175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MID13_13180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MID13_13185	COG3079	Belongs to the UPF0149 family
MID13_13190	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MID13_13200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MID13_13205	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MID13_13210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MID13_13225	COG1279	arginine transmembrane transporter activity
MID13_13235	COG0668	transmembrane transport
MID13_13240	COG0191	fructose-bisphosphate aldolase activity
MID13_13255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MID13_13260	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MID13_13270	COG3091	SprT-like family
MID13_13275	COG2356	endonuclease I
MID13_13285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MID13_13290	COG0189	ligase activity
MID13_13295	COG1678	Uncharacterized ACR, COG1678
MID13_13320	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MID13_13325	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MID13_13330	COG0762	integral membrane protein
MID13_13345	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MID13_13350	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MID13_13355	COG2066	Belongs to the glutaminase family
MID13_13370	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
MID13_13375	COG0741	lytic transglycosylase activity
MID13_13530	COG0795	lipopolysaccharide-transporting ATPase activity
MID13_13535	COG0795	lipopolysaccharide-transporting ATPase activity
MID13_13540	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MID13_13545	COG2927	DNA polymerase III (CHI subunit)
MID13_13550	COG0525	valine-tRNA ligase activity
MID13_13555	COG4783	chaperone-mediated protein folding
MID13_13560	COG4269	membrane
MID13_13570	COG0456	acetyltransferase
MID13_13600	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
MID13_13605	COG0251	oxidation-reduction process
MID13_13610	COG0204	Acyl-transferase
MID13_13615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MID13_13620	COG5007	Belongs to the BolA IbaG family
MID13_13630	COG2854	intermembrane phospholipid transfer
MID13_13635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MID13_13640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MID13_13645	COG1127	ABC transporter
MID13_13655	COG0517	IMP dehydrogenase activity
MID13_13655	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MID13_13660	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MID13_13670	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MID13_13675	COG1137	ATPase activity
MID13_13685	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MID13_13690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID13_13695	COG1660	Displays ATPase and GTPase activities
MID13_13700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID13_13705	COG2239	Acts as a magnesium transporter
MID13_13710	COG0312	modulator of DNA gyrase
MID13_13715	COG3028	Belongs to the UPF0307 family
MID13_13720	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
MID13_13725	COG1178	ABC-type Fe3 transport system permease component
MID13_13735	COG0163	prenyltransferase activity
MID13_13740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MID13_13745	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MID13_13755	COG2105	PFAM AIG2 family protein
MID13_13765	COG0729	surface antigen
MID13_13770	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MID13_13780	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
MID13_13815	COG0529	Catalyzes the synthesis of activated sulfate
MID13_13820	COG3273	potassium ion transport
MID13_13820	COG0471	metal ion transport
MID13_13825	COG2895	sulfate adenylyltransferase (ATP) activity
MID13_13830	COG0175	sulfate reduction
MID13_13835	COG0737	Belongs to the 5'-nucleotidase family
MID13_13880	COG2153	protein acetylation
MID13_13890	COG3061	Opacity-associated protein A
MID13_13890	COG3266	domain, Protein
MID13_13895	COG0545	Peptidyl-prolyl cis-trans isomerase
MID13_13915	COG0203	ribosomal protein L17
MID13_13920	COG0202	RNA polymerase activity
MID13_13925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MID13_13930	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MID13_13935	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MID13_13940	COG0257	Belongs to the bacterial ribosomal protein bL36 family
MID13_13945	COG0201	protein transport
MID13_13950	COG0200	Binds to the 23S rRNA
MID13_13955	COG1841	ribosomal large subunit assembly
MID13_13960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MID13_13965	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MID13_13970	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MID13_13975	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MID13_13980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MID13_13985	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MID13_13990	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MID13_13995	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MID13_14000	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MID13_14010	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MID13_14015	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MID13_14025	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MID13_14030	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MID13_14035	COG0089	rRNA binding
MID13_14040	COG0088	Forms part of the polypeptide exit tunnel
MID13_14045	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MID13_14055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MID13_14060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MID13_14080	COG2923	Belongs to the DsrF TusC family
MID13_14085	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MID13_14090	COG2964	Protein conserved in bacteria
MID13_14095	COG0545	Peptidyl-prolyl cis-trans isomerase
MID13_14105	COG2900	Belongs to the SlyX family
MID13_14110	COG1446	asparaginase
MID13_14115	COG1047	Peptidyl-prolyl cis-trans
MID13_14130	COG2249	NAD(P)H dehydrogenase (quinone) activity
MID13_14135	COG0488	(ABC) transporter
MID13_14145	COG0429	hydrolase of the alpha beta-hydrolase fold
MID13_14150	COG3089	Belongs to the UPF0270 family
MID13_14155	COG3954	Phosphoribulokinase
MID13_14160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MID13_14170	COG1012	belongs to the aldehyde dehydrogenase family
MID13_14180	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MID13_14185	COG0512	Glutamine amidotransferase of anthranilate synthase
MID13_14190	COG2356	endonuclease I
MID13_14210	COG0180	Tryptophanyl-tRNA synthetase
MID13_14215	COG0546	phosphoglycolate phosphatase activity
MID13_14220	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MID13_14225	COG0338	D12 class N6 adenine-specific DNA methyltransferase
MID13_14235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MID13_14270	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
MID13_14280	COG0678	peroxiredoxin activity
MID13_14280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MID13_14285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MID13_14290	COG0251	oxidation-reduction process
MID13_14300	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MID13_14300	COG0165	Argininosuccinate lyase
MID13_14315	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MID13_14320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MID13_14325	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MID13_14335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MID13_14340	COG0460	homoserine dehydrogenase
MID13_14340	COG0527	aspartate kinase activity
MID13_14345	COG0626	cystathionine gamma-synthase activity
MID13_14350	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
MID13_14355	COG0281	malic enzyme
MID13_14360	COG0254	rRNA binding
MID13_14365	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MID13_14370	COG1609	Transcriptional regulator
MID13_14380	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MID13_14385	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MID13_14390	COG1575	Belongs to the MenA family. Type 1 subfamily
MID13_14395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MID13_14400	COG3074	FtsZ-dependent cytokinesis
MID13_14405	COG1494	fructose-1,6-bisphosphatase
MID13_14420	COG3152	Membrane
MID13_14430	COG0149	triose-phosphate isomerase activity
MID13_14435	COG0205	6-phosphofructokinase activity
MID13_14440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MID13_14450	COG0745	RESPONSE REGULATOR receiver
MID13_14455	COG2205	protein histidine kinase activity
MID13_14465	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MID13_14470	COG3030	protein affecting phage T7 exclusion by the F plasmid
MID13_14475	COG1027	Aspartate ammonia-lyase
MID13_14480	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MID13_14485	COG1288	antiporter activity
MID13_14495	COG0549	Belongs to the carbamate kinase family
MID13_14500	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MID13_14505	COG0540	Belongs to the ATCase OTCase family
MID13_14510	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
MID13_14515	COG1438	arginine binding
MID13_14520	COG4232	protein-disulfide reductase activity
MID13_14530	COG3263	regulation of cellular component size
MID13_14540	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MID13_14555	COG0784	Response regulator, receiver
MID13_14555	COG2205	protein histidine kinase activity
MID13_14555	COG2198	Histidine kinase
MID13_14560	COG2814	Major facilitator Superfamily
MID13_14575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MID13_14580	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MID13_14585	COG0511	ligase activity, forming carbon-carbon bonds
MID13_14590	COG0439	Biotin carboxylase
MID13_14595	COG2264	protein methyltransferase activity
MID13_14600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MID13_14605	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MID13_14610	COG0789	Transcriptional regulator
MID13_14615	COG0138	bifunctional purine biosynthesis protein purh
MID13_14620	COG0151	Belongs to the GarS family
MID13_14635	COG1253	flavin adenine dinucleotide binding
MID13_14640	COG3068	Protein conserved in bacteria
MID13_14650	COG1573	uracil-dna glycosylase
MID13_14660	COG2816	NAD+ diphosphatase activity
MID13_14665	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
MID13_14680	COG0222	ribosome binding
MID13_14685	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MID13_14690	COG0081	regulation of translation
MID13_14700	COG0250	Participates in transcription elongation, termination and antitermination
MID13_14705	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MID13_14710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MID13_14735	COG1072	(Pantothenic acid kinase))
MID13_14745	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MID13_14755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MID13_14840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MID13_14850	COG4206	TonB-dependent receptor
MID13_14855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MID13_14870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MID13_14875	COG0534	Mate efflux family protein
MID13_14880	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MID13_14885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MID13_14890	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MID13_14895	COG2937	Belongs to the GPAT DAPAT family
MID13_14900	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MID13_14905	COG3161	chorismate lyase activity
MID13_14910	COG1580	Controls the rotational direction of flagella during chemotaxis
MID13_14915	COG0705	Rhomboid family
MID13_14920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MID13_14930	COG2177	Part of the ABC transporter FtsEX involved in
MID13_14935	COG2884	Cell division ATP-binding protein ftsE
MID13_14940	COG0552	protein localization to endoplasmic reticulum
MID13_14945	COG0742	ribosomal rna small subunit methyltransferase
MID13_14955	COG2095	MarC family integral membrane protein
MID13_14995	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MID13_15000	COG0640	Transcriptional regulator
MID13_15005	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
MID13_15010	COG1280	lysine exporter protein (LysE YggA)
MID13_15015	COG2267	carboxylic ester hydrolase activity
MID13_15020	COG0561	phosphatase activity
MID13_15035	COG3148	PFAM DTW domain containing protein
MID13_15040	COG2200	EAL domain
MID13_15040	COG3287	FIST C domain
MID13_15040	COG2199	diguanylate cyclase activity
MID13_15045	COG2199	diguanylate cyclase activity
MID13_15045	COG2200	EAL domain
MID13_15045	COG3287	FIST C domain
MID13_15050	COG1011	Hydrolase
MID13_15055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MID13_15065	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MID13_15070	COG0019	diaminopimelate decarboxylase activity
MID13_15080	COG1965	Belongs to the frataxin family
MID13_15085	COG3072	Adenylate cyclase
MID13_15090	COG0181	hydroxymethylbilane synthase activity
MID13_15095	COG1587	Uroporphyrinogen-III synthase
MID13_15100	COG2959	enzyme of heme biosynthesis
MID13_15105	COG3071	HemY protein
MID13_15160	COG2871	sodium ion transport
MID13_15165	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MID13_15180	COG3118	belongs to the thioredoxin family
MID13_15185	COG0513	Belongs to the DEAD box helicase family
MID13_15190	COG0248	Ppx GppA phosphatase
MID13_15195	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MID13_15205	COG0514	ATP-dependent DNA helicase (RecQ)
MID13_15210	COG2962	Rard protein
MID13_15220	COG1280	lysine exporter protein (LysE YggA)
MID13_15225	COG0405	Gamma-glutamyltransferase
MID13_15235	COG0210	DNA helicase
MID13_15245	COG3220	belongs to the UPF0276 family
MID13_15275	COG0006	proline dipeptidase activity
MID13_15275	COG0006	proline dipeptidase activity
MID13_15285	COG2022	thiamine diphosphate biosynthetic process
MID13_15290	COG2104	thiamine diphosphate biosynthetic process
MID13_15295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
MID13_15300	COG0352	thiamine-phosphate diphosphorylase activity
MID13_15305	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MID13_15315	COG2132	Multicopper oxidase
MID13_15360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MID13_15370	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MID13_15375	COG0408	coproporphyrinogen oxidase activity
MID13_15380	COG0009	L-threonylcarbamoyladenylate synthase
MID13_15385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MID13_15390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MID13_15395	COG0551	DNA topoisomerase type I activity
MID13_15400	COG2922	Belongs to the Smg family
MID13_15405	COG0758	DNA mediated transformation
MID13_15425	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MID13_15425	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MID13_15430	COG0569	domain protein
MID13_15435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MID13_15445	COG1272	protein, Hemolysin III
MID13_15450	COG4326	sporulation control protein
MID13_15460	COG3084	Protein conserved in bacteria
MID13_15475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MID13_15485	COG0606	chelatase, subunit chli
MID13_15495	COG3978	acetolactate synthase activity
MID13_15500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MID13_15505	COG0129	dihydroxy-acid dehydratase activity
MID13_15515	COG0583	DNA-binding transcription factor activity
MID13_15520	COG2814	Major facilitator Superfamily
MID13_15525	COG3706	GGDEF domain
MID13_15535	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MID13_15540	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MID13_15545	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MID13_15550	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MID13_15555	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MID13_15560	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MID13_15575	COG3312	ion transport
MID13_15580	COG1475	DNA binding
MID13_15585	COG1192	Involved in chromosome partitioning
MID13_15590	COG0357	Ribosomal RNA small subunit methyltransferase G
MID13_15595	COG0445	tRNA wobble uridine modification
MID13_15600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MID13_15610	COG0706	membrane insertase activity
MID13_15615	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MID13_15620	COG0594	ribonuclease P activity
MID13_15625	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MID13_15630	COG1126	abc transporter atp-binding protein
MID13_15685	COG0259	pyridoxamine-phosphate oxidase activity
MID13_15695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MID13_15720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MID13_15750	COG1132	(ABC) transporter
MID13_15775	COG2194	sulfuric ester hydrolase activity
MID13_15790	COG1660	Displays ATPase and GTPase activities
MID13_15805	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MID13_15815	COG4145	pantothenate transmembrane transporter activity
MID13_15820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MID13_15825	COG0800	Aldolase
MID13_15845	COG2204	response regulator
MID13_15860	COG0579	oxidoreductase
MID13_15880	COG2205	protein histidine kinase activity
MID13_15885	COG0745	RESPONSE REGULATOR receiver
MID13_15900	COG1522	sequence-specific DNA binding
MID13_15910	COG1473	amidohydrolase
MID13_15915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MID13_15925	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MID13_15945	COG1309	transcriptional regulator
MID13_15950	COG1012	belongs to the aldehyde dehydrogenase family
MID13_15970	COG0517	IMP dehydrogenase activity
MID13_15970	COG4175	Glycine betaine
MID13_15975	COG1846	Transcriptional regulator
MID13_16005	COG0641	radical SAM
MID13_16010	COG1309	transcriptional regulator
MID13_16020	COG0456	acetyltransferase
MID13_16040	COG2211	Major facilitator Superfamily
MID13_16045	COG1486	melibiose metabolic process
MID13_16050	COG2169	Transcriptional regulator
MID13_16055	COG3408	Glycogen debranching enzyme
MID13_16055	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
MID13_16070	COG2207	Transcriptional regulator
MID13_16090	COG0110	maltose O-acetyltransferase activity
MID13_16095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MID13_16105	COG2918	glutathione biosynthetic process
MID13_16110	COG1132	(ABC) transporter
MID13_16115	COG1132	(ABC) transporter
MID13_16125	COG2207	Transcriptional regulator
MID13_16130	COG2814	Major facilitator Superfamily
MID13_16140	COG0604	alcohol dehydrogenase
MID13_16140	COG1028	Short-chain dehydrogenase reductase Sdr
MID13_16140	COG3321	synthase
MID13_16165	COG0646	methionine synthase
MID13_16165	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MID13_16250	COG0583	DNA-binding transcription factor activity
MID13_16260	COG1288	antiporter activity
MID13_16270	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MID13_16285	COG0346	lactoylglutathione lyase activity
MID13_16295	COG3300	MHYT domain
MID13_16295	COG5001	Diguanylate cyclase
MID13_16310	COG2723	6-phospho-beta-galactosidase activity
MID13_16315	COG1609	Transcriptional regulator
MID13_16320	COG0110	maltose O-acetyltransferase activity
MID13_16325	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MID13_16330	COG1301	dicarboxylic acid transport
MID13_16345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MID13_16355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MID13_16370	COG0549	Belongs to the carbamate kinase family
MID13_16375	COG0531	amino acid
MID13_16380	COG2957	Belongs to the agmatine deiminase family
MID13_16395	COG1794	racemase activity, acting on amino acids and derivatives
MID13_16405	COG0561	phosphatase activity
MID13_16415	COG1454	alcohol dehydrogenase
MID13_16420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MID13_16430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MID13_16440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MID13_16445	COG1263	PTS System
MID13_16445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID13_16460	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MID13_16465	COG1349	DNA-binding transcription factor activity
MID13_16470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MID13_16475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
MID13_16485	COG0583	DNA-binding transcription factor activity
MID13_16490	COG0798	PFAM Bile acid sodium symporter
MID13_16510	COG4783	chaperone-mediated protein folding
MID13_16525	COG0561	phosphatase activity
MID13_16545	COG0583	DNA-binding transcription factor activity
MID13_16580	COG1349	DNA-binding transcription factor activity
MID13_16585	COG2084	Dehydrogenase
MID13_16590	COG3395	kinase activity
MID13_16595	COG0235	Class ii aldolase
MID13_16600	COG3622	Belongs to the hyi family
MID13_16605	COG2610	gluconate transmembrane transporter activity
MID13_16610	COG1929	Belongs to the glycerate kinase type-1 family
MID13_16615	COG0753	catalase activity
MID13_16620	COG4667	esterase of the alpha-beta hydrolase superfamily
MID13_16625	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MID13_16635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MID13_16640	COG0204	Acyl-transferase
MID13_16660	COG4580	involved in the transport of maltose and maltodextrins
MID13_16695	COG3258	Cytochrome c
MID13_16700	COG2863	cytochrome
MID13_16735	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MID13_16740	COG1162	GTPase activity
MID13_16750	COG1999	signal sequence binding
MID13_16770	COG0058	SHG alpha-glucan phosphorylase activity
MID13_16775	COG1640	4-alpha-glucanotransferase
MID13_16780	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MID13_16795	COG1122	ATPase activity
MID13_16800	COG4720	Psort location CytoplasmicMembrane, score
MID13_16805	COG1566	PFAM secretion protein HlyD family protein
MID13_16835	COG0813	purine-nucleoside phosphorylase activity
MID13_16840	COG1388	LysM domain
MID13_16840	COG1376	ErfK ybiS ycfS ynhG family protein
MID13_16850	COG0513	Belongs to the DEAD box helicase family
MID13_16855	COG3240	lipase activity
MID13_16860	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
MID13_16870	COG1770	oligopeptidase
MID13_16875	COG4771	TonB-dependent receptor
MID13_16895	COG0840	transmembrane signaling receptor activity
MID13_16905	COG0573	inorganic phosphate transmembrane transporter activity
MID13_16910	COG0581	inorganic phosphate transmembrane transporter activity
MID13_16915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MID13_16930	COG2304	oxidoreductase activity
MID13_16935	COG2304	oxidoreductase activity
MID13_16950	COG0714	Associated with various cellular activities
MID13_16955	COG0840	transmembrane signaling receptor activity
MID13_16965	COG3842	ATPase activity
MID13_16975	COG1175	transmembrane transport
MID13_16980	COG3833	ABC-type maltose transport systems, permease component
MID13_16995	COG4166	transmembrane transport
MID13_17020	COG0577	efflux transmembrane transporter activity
MID13_17025	COG1136	(ABC) transporter
MID13_17030	COG2356	endonuclease I
MID13_17045	COG1566	PFAM secretion protein HlyD family protein
MID13_17115	COG1012	belongs to the aldehyde dehydrogenase family
MID13_17120	COG1414	Transcriptional regulator
MID13_17125	COG0280	phosphate acetyltransferase
MID13_17130	COG0730	response to heat
MID13_17160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MID13_17165	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MID13_17170	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MID13_17175	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MID13_17175	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MID13_17190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MID13_17200	COG2354	Protein conserved in bacteria
MID13_17205	COG0418	dihydroorotase activity
MID13_17215	COG0633	Ferredoxin
MID13_17215	COG3217	Mosc domain protein beta barrel domain protein
MID13_17220	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MID13_17265	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MID13_17270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID13_17280	COG0848	biopolymer transport protein
MID13_17285	COG0811	peptide transport
MID13_17290	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
MID13_17300	COG3721	Heme iron utilization protein
MID13_17305	COG0748	coenzyme F420 binding
MID13_17310	COG2096	Adenosyltransferase
MID13_17315	COG0835	chemotaxis
MID13_17315	COG0784	Response regulator, receiver
MID13_17320	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MID13_17325	COG0366	Alpha amylase catalytic
MID13_17335	COG3314	Sporulation integral membrane protein YlbJ
MID13_17360	COG0739	heme binding
MID13_17365	COG5001	Diguanylate cyclase
MID13_17370	COG0583	DNA-binding transcription factor activity
MID13_17375	COG2814	Major facilitator Superfamily
MID13_17390	COG0697	spore germination
MID13_17395	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MID13_17410	COG3118	belongs to the thioredoxin family
MID13_17415	COG4232	protein-disulfide reductase activity
MID13_17425	COG0668	transmembrane transport
MID13_17435	COG2197	response regulator
MID13_17470	COG4989	oxidoreductase activity
MID13_17480	COG0513	Belongs to the DEAD box helicase family
MID13_17495	COG2176	DNA-directed DNA polymerase activity
MID13_17505	COG0513	Belongs to the DEAD box helicase family
MID13_17510	COG0778	Nitroreductase
MID13_17525	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
MID13_17530	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MID13_17535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MID13_17540	COG0667	Aldo Keto reductase
MID13_17550	COG2195	Cleaves the N-terminal amino acid of tripeptides
MID13_17585	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MID13_17600	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
MID13_17605	COG0513	Belongs to the DEAD box helicase family
MID13_17610	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MID13_17625	COG1396	sequence-specific DNA binding
MID13_17630	COG3135	benzoate transporter
MID13_17645	COG0604	alcohol dehydrogenase
MID13_17650	COG0019	diaminopimelate decarboxylase activity
MID13_17655	COG4264	IucA IucC family
MID13_17680	COG4772	TonB-dependent receptor
MID13_17685	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
MID13_17690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID13_17695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID13_17700	COG1120	ATPase activity
MID13_17715	COG0366	Alpha amylase catalytic
MID13_17725	COG0583	DNA-binding transcription factor activity
MID13_17730	COG0534	Mate efflux family protein
MID13_17765	COG0516	GMP reductase activity
MID13_17775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MID13_17810	COG0697	spore germination
MID13_17815	COG0351	phosphomethylpyrimidine kinase
MID13_17820	COG1116	anion transmembrane transporter activity
MID13_17825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MID13_17830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MID13_17835	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MID13_17840	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MID13_17860	COG0583	DNA-binding transcription factor activity
MID13_17890	COG3706	GGDEF domain
MID13_17900	COG1566	PFAM secretion protein HlyD family protein
MID13_17910	COG0628	permease
MID13_17935	COG4607	ABC-type enterochelin transport system periplasmic component
MID13_17940	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID13_17945	COG4605	iron ion homeostasis
MID13_17950	COG4604	ABC transporter, ATP-binding protein
MID13_17965	COG0583	DNA-binding transcription factor activity
MID13_17970	COG2814	Major facilitator Superfamily
MID13_17975	COG1803	Methylglyoxal synthase
MID13_17980	COG1879	ABC-type sugar transport system periplasmic component
MID13_18015	COG0625	glutathione transferase activity
MID13_18020	COG1252	NADH dehydrogenase
MID13_18055	COG0745	RESPONSE REGULATOR receiver
MID13_18080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MID13_18090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MID13_18090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MID13_18090	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
MID13_18095	COG1105	Belongs to the carbohydrate kinase PfkB family
MID13_18100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID13_18100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID13_18105	COG1609	Transcriptional regulator
MID13_18110	COG2815	serine threonine protein kinase
MID13_18110	COG0515	serine threonine protein kinase
MID13_18115	COG2223	nitrite transmembrane transporter activity
MID13_18125	COG2146	nitrite reductase [NAD(P)H] activity
MID13_18125	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MID13_18130	COG0243	molybdopterin cofactor binding
MID13_18240	COG0583	DNA-binding transcription factor activity
MID13_18265	COG1609	Transcriptional regulator
MID13_18270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MID13_18275	COG1879	ABC-type sugar transport system periplasmic component
MID13_18280	COG1172	Belongs to the binding-protein-dependent transport system permease family
MID13_18285	COG1129	ABC transporter
MID13_18290	COG1869	D-ribose catabolic process
MID13_18315	COG4166	transmembrane transport
MID13_18320	COG4174	ABC transporter (Permease)
MID13_18325	COG4239	(ABC) transporter, permease
MID13_18330	COG4172	Belongs to the ABC transporter superfamily
MID13_18335	COG4174	ABC transporter (Permease)
MID13_18340	COG4239	(ABC) transporter, permease
MID13_18345	COG0747	negative chemotaxis
MID13_18350	COG0444	Belongs to the ABC transporter superfamily
MID13_18355	COG4608	Belongs to the ABC transporter superfamily
MID13_18370	COG0745	RESPONSE REGULATOR receiver
MID13_18375	COG0642	Histidine kinase
MID13_18385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MID13_18410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MID13_18415	COG1609	Transcriptional regulator
MID13_18425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MID13_18445	COG0583	DNA-binding transcription factor activity
MID13_18455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MID13_18465	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MID13_18475	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MID13_18490	COG0356	it plays a direct role in the translocation of protons across the membrane
MID13_18500	COG0583	DNA-binding transcription factor activity
MID13_18510	COG1012	belongs to the aldehyde dehydrogenase family
MID13_18520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MID13_18560	COG3278	Belongs to the heme-copper respiratory oxidase family
MID13_18580	COG3300	MHYT domain
MID13_18580	COG5001	Diguanylate cyclase
MID13_18590	COG1280	lysine exporter protein (LysE YggA)
MID13_18595	COG0384	phenazine biosynthesis protein PhzF
MID13_18630	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
MID13_18640	COG0456	acetyltransferase
MID13_18650	COG2885	chlorophyll binding
MID13_18655	COG0583	DNA-binding transcription factor activity
MID13_18670	COG1566	PFAM secretion protein HlyD family protein
MID13_18680	COG0733	neurotransmitter:sodium symporter activity
MID13_18685	COG4221	oxidoreductase activity
MID13_18690	COG2197	response regulator
MID13_18695	COG3119	arylsulfatase activity
MID13_18700	COG0641	radical SAM
MID13_18715	COG0714	Associated with various cellular activities
MID13_18755	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
MID13_18760	COG2205	protein histidine kinase activity
MID13_18760	COG0784	Response regulator, receiver
MID13_18770	COG3119	arylsulfatase activity
MID13_18775	COG3119	arylsulfatase activity
MID13_18785	COG0714	Associated with various cellular activities
MID13_18815	COG0583	DNA-binding transcription factor activity
MID13_18820	COG5001	Diguanylate cyclase
MID13_18820	COG3300	MHYT domain
MID13_18845	COG0641	radical SAM
MID13_18855	COG0405	Gamma-glutamyltransferase
MID13_18860	COG0840	transmembrane signaling receptor activity
MID13_18885	COG0784	Response regulator, receiver
MID13_18885	COG5002	protein histidine kinase activity
MID13_18885	COG2205	protein histidine kinase activity
MID13_18905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MID13_18930	COG0745	RESPONSE REGULATOR receiver
MID13_18935	COG1366	Belongs to the anti-sigma-factor antagonist family
MID13_18940	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MID13_19025	COG5002	protein histidine kinase activity
MID13_19030	COG1881	PFAM PEBP family protein
MID13_19040	COG2807	transmembrane transport
MID13_19045	COG0583	DNA-binding transcription factor activity
MID13_19050	COG3048	D-serine ammonia-lyase activity
MID13_19080	COG1280	lysine exporter protein (LysE YggA)
MID13_19095	COG0534	Mate efflux family protein
MID13_19125	COG0509	glycine decarboxylation via glycine cleavage system
MID13_19165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MID13_19170	COG3706	GGDEF domain
MID13_19180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MID13_19195	COG0784	Response regulator, receiver
MID13_19195	COG3437	response regulator, receiver
MID13_19200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MID13_19205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MID13_19210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MID13_19220	COG0814	amino acid
MID13_19225	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
MID13_19230	COG0513	Belongs to the DEAD box helicase family
MID13_19255	COG2200	EAL domain
MID13_19270	COG3038	cytochrome b561
MID13_19275	COG2353	YceI-like domain
MID13_19280	COG2116	formate transmembrane transporter activity
MID13_19285	COG0583	DNA-binding transcription factor activity
MID13_19295	COG3593	DNA synthesis involved in DNA repair
MID13_19300	COG0737	Belongs to the 5'-nucleotidase family
MID13_19305	COG0861	Integral membrane protein TerC family
MID13_19320	COG0513	Belongs to the DEAD box helicase family
MID13_19330	COG2267	carboxylic ester hydrolase activity
MID13_19345	COG0501	Belongs to the peptidase M48B family
MID13_19350	COG2050	protein possibly involved in aromatic compounds catabolism
MID13_19360	COG4533	DNA binding
MID13_19390	COG0768	penicillin binding
MID13_19400	COG5001	Diguanylate cyclase
MID13_19400	COG1716	ATPase activity
MID13_19405	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MID13_19415	COG4181	ATPase activity
MID13_19420	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MID13_19430	COG1984	allophanate hydrolase subunit 2
MID13_19435	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MID13_19445	COG4771	TonB-dependent receptor
MID13_19455	COG5001	Diguanylate cyclase
MID13_19455	COG3300	MHYT domain
MID13_19470	COG1629	transport
MID13_19470	COG4771	TonB-dependent receptor
MID13_19475	COG0583	DNA-binding transcription factor activity
MID13_19480	COG0045	succinate-CoA ligase (ADP-forming) activity
MID13_19480	COG1042	CoA-binding domain protein
MID13_19480	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MID13_19485	COG3266	domain, Protein
MID13_19490	COG1181	Belongs to the D-alanine--D-alanine ligase family
MID13_19505	COG0023	Translation Initiation Factor
MID13_19515	COG3140	Belongs to the UPF0181 family
MID13_19540	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MID13_19545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MID13_19560	COG3706	GGDEF domain
MID13_19570	COG5001	Diguanylate cyclase
MID13_19570	COG4251	negative regulation of phosphorylation
MID13_19570	COG3706	GGDEF domain
MID13_19570	COG2203	Gaf domain
MID13_19580	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MID13_19585	COG4149	molybdate abc transporter
MID13_19590	COG0725	ABC transporter, periplasmic molybdate-binding protein
MID13_19615	COG0488	(ABC) transporter
MID13_19620	COG0189	ligase activity
MID13_19620	COG4067	protein conserved in archaea
MID13_19640	COG0602	queuosine metabolic process
MID13_19645	COG1328	CTP reductase activity
MID13_19675	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MID13_19680	COG3118	belongs to the thioredoxin family
MID13_19690	COG0318	PFAM AMP-dependent synthetase and ligase
MID13_19720	COG0534	Mate efflux family protein
MID13_19745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MID13_19745	COG1321	iron dependent repressor
MID13_19750	COG1121	(ABC) transporter
MID13_19755	COG0803	Belongs to the bacterial solute-binding protein 9 family
MID13_19800	COG0848	biopolymer transport protein
MID13_19805	COG0811	peptide transport
MID13_19810	COG0811	peptide transport
MID13_19820	COG4774	siderophore transport
MID13_19825	COG1301	dicarboxylic acid transport
MID13_19830	COG2205	protein histidine kinase activity
MID13_19835	COG0745	RESPONSE REGULATOR receiver
MID13_19850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MID13_19850	COG1648	precorrin-2 dehydrogenase activity
MID13_19855	COG2116	formate transmembrane transporter activity
MID13_19865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MID13_19905	COG3712	iron ion homeostasis
MID13_19940	COG0848	biopolymer transport protein
MID13_19975	COG2425	protein containing a von Willebrand factor type A (vWA) domain
MID13_19980	COG0714	Associated with various cellular activities
MID13_19985	COG0494	nUDIX hydrolase
MID13_19990	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
MID13_20010	COG2197	response regulator
MID13_20020	COG3706	GGDEF domain
MID13_20040	COG2205	protein histidine kinase activity
MID13_20040	COG0784	Response regulator, receiver
MID13_20095	COG0076	glutamate decarboxylase activity
MID13_20100	COG2207	Transcriptional regulator
MID13_20115	COG3706	GGDEF domain
MID13_20150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MID13_20155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MID13_20160	COG2067	long-chain fatty acid transport protein
MID13_20165	COG2267	carboxylic ester hydrolase activity
MID13_20180	COG3069	C4-dicarboxylate transmembrane transporter activity
MID13_20190	COG2197	response regulator
MID13_20195	COG3850	Histidine kinase
MID13_20210	COG0243	molybdopterin cofactor binding
MID13_20220	COG3005	denitrification pathway
MID13_20240	COG0183	Belongs to the thiolase family
MID13_20285	COG0745	RESPONSE REGULATOR receiver
MID13_20315	COG0513	Belongs to the DEAD box helicase family
MID13_20325	COG0523	cobalamin synthesis protein
MID13_20330	COG0038	chloride channel
MID13_20340	COG1017	nitric oxide dioxygenase activity
MID13_20340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MID13_20345	COG3604	Transcriptional regulator
MID13_20365	COG0545	Peptidyl-prolyl cis-trans isomerase
MID13_20370	COG1309	transcriptional regulator
MID13_20375	COG2130	NADP-dependent
MID13_20385	COG0564	pseudouridine synthase activity
MID13_20395	COG0583	DNA-binding transcription factor activity
MID13_20405	COG1686	Belongs to the peptidase S11 family
MID13_20420	COG3706	GGDEF domain
MID13_20430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MID13_20440	COG0384	phenazine biosynthesis protein PhzF
MID13_20445	COG3059	membrane
MID13_20465	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MID13_20485	COG0251	oxidation-reduction process
MID13_20490	COG2207	Transcriptional regulator
MID13_20495	COG1979	alcohol dehydrogenase
MID13_20500	COG1126	abc transporter atp-binding protein
MID13_20505	COG0765	amino acid transport
MID13_20515	COG0765	amino acid transport
MID13_20525	COG1629	transport
MID13_20525	COG4771	TonB-dependent receptor
MID13_20530	COG4977	sequence-specific DNA binding
MID13_20540	COG1280	lysine exporter protein (LysE YggA)
MID13_20575	COG2824	Alkylphosphonate utilization operon protein PhnA
MID13_20610	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MID13_20615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MID13_20635	COG0446	pyridine nucleotide-disulphide oxidoreductase
MID13_20635	COG1902	pentaerythritol trinitrate reductase activity
MID13_20645	COG3710	Transcriptional regulator
MID13_20660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MID13_20665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MID13_20675	COG2985	domain, Protein
MID13_20695	COG1024	Enoyl-CoA hydratase
MID13_20700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MID13_20710	COG4774	siderophore transport
MID13_20725	COG1120	ATPase activity
MID13_20735	COG2133	pyrroloquinoline quinone binding
MID13_20740	COG1278	Cold shock
MID13_20745	COG4681	YaeQ
MID13_20755	COG0302	gtp cyclohydrolase
MID13_20785	COG2897	thiosulfate sulfurtransferase activity
MID13_20790	COG2203	Gaf domain
MID13_20790	COG3706	GGDEF domain
MID13_20790	COG4251	negative regulation of phosphorylation
MID13_20790	COG5001	Diguanylate cyclase
MID13_20810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MID13_20820	COG0840	transmembrane signaling receptor activity
MID13_20825	COG1522	sequence-specific DNA binding
MID13_20850	COG0210	DNA helicase
MID13_20855	COG1289	transmembrane transporter activity
MID13_20875	COG0583	DNA-binding transcription factor activity
MID13_20880	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MID13_20885	COG1328	CTP reductase activity
MID13_20915	COG1011	Hydrolase
MID13_20925	COG1454	alcohol dehydrogenase
MID13_20945	COG2249	NAD(P)H dehydrogenase (quinone) activity
MID13_20980	COG0156	8-amino-7-oxononanoate synthase activity
MID13_21000	COG0346	lactoylglutathione lyase activity
MID13_21020	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MID13_21025	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MID13_21040	COG0393	Putative heavy-metal-binding
MID13_21070	COG1132	(ABC) transporter
MID13_21075	COG1132	(ABC) transporter
MID13_21080	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MID13_21100	COG1760	l-serine dehydratase
MID13_21105	COG3104	oligopeptide transport
MID13_21110	COG2375	cellular response to nickel ion
MID13_21115	COG1609	Transcriptional regulator
MID13_21120	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MID13_21125	COG3265	gluconokinase activity
MID13_21130	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MID13_21140	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MID13_21150	COG2188	Transcriptional regulator
MID13_21160	COG3842	ATPase activity
MID13_21165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MID13_21170	COG1840	ABC-type Fe3 transport system, periplasmic component
MID13_21180	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MID13_21190	COG2885	chlorophyll binding
MID13_21195	COG1765	OsmC-like protein
MID13_21200	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MID13_21200	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MID13_21205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MID13_21210	COG0569	domain protein
MID13_21215	COG0668	transmembrane transport
MID13_21220	COG0662	Cupin 2, conserved barrel domain protein
MID13_21220	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
MID13_21235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MID13_21240	COG3530	Putative quorum-sensing-regulated virulence factor
MID13_21260	COG0109	protoheme IX farnesyltransferase activity
MID13_21285	COG1845	cytochrome c oxidase, subunit III
MID13_21295	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MID13_21300	COG1565	acr, cog1565
MID13_21300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MID13_21305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MID13_21310	COG1280	lysine exporter protein (LysE YggA)
MID13_21315	COG0179	Fumarylacetoacetate (FAA) hydrolase
MID13_21325	COG0443	Heat shock 70 kDa protein
MID13_21355	COG2827	Endonuclease containing a URI domain
MID13_21360	COG3132	Protein of unknown function, DUF480
MID13_21370	COG2926	Belongs to the UPF0265 family
MID13_21385	COG5002	protein histidine kinase activity
MID13_21385	COG2205	protein histidine kinase activity
MID13_21385	COG0784	Response regulator, receiver
MID13_21395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MID13_21400	COG1151	hydroxylamine reductase activity
MID13_21435	COG0531	amino acid
MID13_21450	COG4413	Urea transporter
MID13_21470	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MID13_21475	COG0402	S-adenosylhomocysteine deaminase activity
MID13_21480	COG1278	Cold shock
MID13_21485	COG3706	GGDEF domain
MID13_21500	COG0513	Belongs to the DEAD box helicase family
MID13_21515	COG4106	trans-aconitate 2-methyltransferase activity
MID13_21520	COG2205	protein histidine kinase activity
MID13_21525	COG0745	RESPONSE REGULATOR receiver
MID13_21530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MID13_21550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MID13_21570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID13_21575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
MID13_21580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MID13_21585	COG2205	protein histidine kinase activity
MID13_21590	COG0745	RESPONSE REGULATOR receiver
MID13_21600	COG5001	Diguanylate cyclase
MID13_21620	COG5001	Diguanylate cyclase
MID13_21630	COG2186	Transcriptional regulator
MID13_21635	COG1131	(ABC) transporter
MID13_21655	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MID13_21655	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MID13_21665	COG0564	pseudouridine synthase activity
MID13_21675	COG2814	Major facilitator Superfamily
MID13_21700	COG2814	Major facilitator Superfamily
MID13_21705	COG4977	sequence-specific DNA binding
MID13_21740	COG4533	DNA binding
MID13_21745	COG0189	ligase activity
MID13_21750	COG0189	ligase activity
MID13_21750	COG4067	protein conserved in archaea
MID13_21765	COG0584	glycerophosphoryl diester phosphodiesterase
MID13_21785	COG0673	inositol 2-dehydrogenase activity
MID13_21795	COG2999	glutathione oxidoreductase activity
MID13_21805	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MID13_21810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MID13_21810	COG0574	Belongs to the PEP-utilizing enzyme family
MID13_21825	COG0110	maltose O-acetyltransferase activity
MID13_21830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MID13_21840	COG3454	Phosphonate metabolism
MID13_21845	COG4778	phosphonate C-P lyase system protein PhnL
MID13_21850	COG4107	phosphonate C-P lyase system protein PhnK
MID13_21855	COG3627	carbon phosphorus lyase activity
MID13_21860	COG3626	phosphonate metabolism
MID13_21865	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
MID13_21870	COG3624	Phosphonate C-P lyase system protein PhnG
MID13_21875	COG2188	Transcriptional regulator
MID13_21880	COG3639	organic phosphonate transmembrane transporter activity
MID13_21885	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MID13_21895	COG2964	Protein conserved in bacteria
MID13_21910	COG0446	pyridine nucleotide-disulphide oxidoreductase
MID13_21920	COG2194	sulfuric ester hydrolase activity
MID13_21990	COG1901	pseudouridine methyltransferase
MID13_22010	COG1595	DNA-templated transcription, initiation
MID13_22015	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MID13_22045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MID13_22055	COG0583	DNA-binding transcription factor activity
MID13_22070	COG1028	Short-chain dehydrogenase reductase Sdr
MID13_22075	COG1733	regulation of RNA biosynthetic process
MID13_22080	COG0583	DNA-binding transcription factor activity
MID13_22085	COG4221	oxidoreductase activity
MID13_22095	COG3047	cAMP biosynthetic process
MID13_22100	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MID13_22105	COG1288	antiporter activity
MID13_22150	COG3639	organic phosphonate transmembrane transporter activity
MID13_22155	COG3639	organic phosphonate transmembrane transporter activity
MID13_22160	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MID13_22185	COG4948	Mandelate Racemase Muconate Lactonizing
MID13_22195	COG0583	DNA-binding transcription factor activity
MID13_22205	COG0656	L-ascorbic acid biosynthetic process
MID13_22210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID13_22215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MID13_22230	COG0191	fructose-bisphosphate aldolase activity
MID13_22250	COG2084	Dehydrogenase
MID13_22255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MID13_22260	COG1349	DNA-binding transcription factor activity
MID13_22285	COG0583	DNA-binding transcription factor activity
MID13_22295	COG0840	transmembrane signaling receptor activity
MID13_22305	COG0697	spore germination
MID13_22310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MID13_22320	COG1757	Na H antiporter
MID13_22325	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MID13_22350	COG2814	Major facilitator Superfamily
MID13_22355	COG2814	Major facilitator Superfamily
MID13_22360	COG1686	Belongs to the peptidase S11 family
MID13_22365	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MID13_22375	COG0814	amino acid
MID13_22380	COG2211	Major facilitator Superfamily
MID13_22385	COG1397	ADP-ribosylglycohydrolase
MID13_22390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MID13_22395	COG2223	nitrite transmembrane transporter activity
MID13_22400	COG2188	Transcriptional regulator
MID13_22405	COG0840	transmembrane signaling receptor activity
MID13_22420	COG3226	Transcriptional regulator
MID13_22430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MID13_22435	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MID13_22445	COG2207	Transcriptional regulator
MID13_22450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID13_22450	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MID13_22450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MID13_22465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MID13_22470	COG3842	ATPase activity
MID13_22475	COG0546	phosphoglycolate phosphatase activity
MID13_22500	COG0583	DNA-binding transcription factor activity
MID13_22505	COG4166	transmembrane transport
MID13_22515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MID13_22520	COG0006	proline dipeptidase activity
MID13_22525	COG0667	Aldo Keto reductase
MID13_22530	COG0583	DNA-binding transcription factor activity
MID13_22540	COG1027	Aspartate ammonia-lyase
MID13_22555	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MID13_22560	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MID13_22585	COG1288	antiporter activity
MID13_22600	COG1280	lysine exporter protein (LysE YggA)
MID13_22615	COG3284	Transcriptional regulator
MID13_22620	COG0840	transmembrane signaling receptor activity
MID13_22625	COG0583	DNA-binding transcription factor activity
MID13_22630	COG0625	glutathione transferase activity
MID13_22635	COG3655	Transcriptional regulator
MID13_22645	COG0583	DNA-binding transcription factor activity
MID13_22685	COG0596	Alpha beta hydrolase
MID13_22690	COG1012	belongs to the aldehyde dehydrogenase family
MID13_22695	COG0583	DNA-binding transcription factor activity
MID13_22700	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
MID13_22705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MID13_22710	COG1418	mRNA catabolic process
MID13_22725	COG2186	Transcriptional regulator
MID13_22735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MID13_22745	COG0402	S-adenosylhomocysteine deaminase activity
MID13_22765	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MID13_22790	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MID13_22795	COG4266	Belongs to the allantoicase family
MID13_22815	COG2252	PERMEase
MID13_22830	COG0402	S-adenosylhomocysteine deaminase activity
MID13_22845	COG0745	RESPONSE REGULATOR receiver
MID13_22850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MID13_22850	COG2205	protein histidine kinase activity
MID13_22865	COG2084	Dehydrogenase
MID13_22870	COG3622	Belongs to the hyi family
MID13_22875	COG3960	tartronate-semialdehyde synthase activity
MID13_22880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MID13_22890	COG2259	Doxx family
MID13_22895	COG0583	DNA-binding transcription factor activity
MID13_22900	COG1846	Transcriptional regulator
MID13_22910	COG0583	DNA-binding transcription factor activity
MID13_22970	COG1067	ATP-dependent peptidase activity
MID13_22980	COG4172	Belongs to the ABC transporter superfamily
MID13_22985	COG1609	Transcriptional regulator
MID13_22995	COG2017	converts alpha-aldose to the beta-anomer
MID13_23000	COG3459	Glycosyltransferase 36 associated
MID13_23005	COG3842	ATPase activity
MID13_23010	COG2723	6-phospho-beta-galactosidase activity
MID13_23015	COG0395	ABC-type sugar transport system, permease component
MID13_23030	COG1609	Transcriptional regulator
MID13_23040	COG1505	serine-type exopeptidase activity
MID13_23045	COG0583	DNA-binding transcription factor activity
MID13_23050	COG1620	l-lactate permease
MID13_23055	COG1304	FMN binding
MID13_23070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MID13_23070	COG2207	Transcriptional regulator
MID13_23075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MID13_23090	COG2015	COG2015, Alkyl sulfatase and related hydrolases
MID13_23095	COG1054	Belongs to the UPF0176 family
MID13_23115	COG1482	cell wall glycoprotein biosynthetic process
MID13_23120	COG2271	Major facilitator Superfamily
MID13_23125	COG3851	Histidine kinase
MID13_23130	COG2197	response regulator
MID13_23155	COG1741	Belongs to the pirin family
MID13_23160	COG3123	guanosine phosphorylase activity
MID13_23175	COG0596	Alpha beta hydrolase
MID13_23220	COG3788	relative of glutathione S-transferase, MAPEG superfamily
MID13_23225	COG0700	Nucleoside recognition
MID13_23230	COG3366	ferrous iron transmembrane transporter activity
MID13_23240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MID13_23250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MID13_23255	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MID13_23280	COG3722	fumarate hydratase activity
MID13_23285	COG0246	Mannitol dehydrogenase
MID13_23290	COG2213	PTS system mannitol-specific
MID13_23290	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MID13_23315	COG0786	glutamate:sodium symporter activity
MID13_23330	COG1942	4-Oxalocrotonate Tautomerase
MID13_23340	COG1595	DNA-templated transcription, initiation
MID13_23345	COG3806	Anti-sigma factor
MID13_23355	COG0415	Belongs to the DNA photolyase family
MID13_23365	COG4221	oxidoreductase activity
MID13_23380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MID13_23405	COG1028	Short-chain dehydrogenase reductase Sdr
MID13_23410	COG0724	RNA recognition motif
MID13_23420	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
MID13_23435	COG1263	PTS System
MID13_23435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
MID13_23440	COG2205	protein histidine kinase activity
MID13_23455	COG1028	Short-chain dehydrogenase reductase Sdr
MID13_23460	COG2814	Major facilitator Superfamily
MID13_23465	COG1902	pentaerythritol trinitrate reductase activity
MID13_23480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MID13_23485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MID13_23495	COG0612	Peptidase, M16
MID13_23500	COG0612	Peptidase, M16
MID13_23505	COG3279	Response regulator of the LytR AlgR family
MID13_23510	COG3275	phosphorelay sensor kinase activity
MID13_23525	COG4591	ABC-type transport system involved in lipoprotein release permease component
MID13_23530	COG1136	(ABC) transporter
MID13_23540	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MID13_23545	COG0583	DNA-binding transcription factor activity
MID13_23560	COG0753	catalase activity
MID13_23565	COG2084	Dehydrogenase
MID13_23580	COG0217	transcriptional regulatory protein
MID13_23595	COG3186	Phenylalanine-4-hydroxylase
MID13_23600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MID13_23610	COG0625	glutathione transferase activity
MID13_23620	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MID13_23650	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MID13_23650	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
MID13_23660	COG0444	Belongs to the ABC transporter superfamily
MID13_23665	COG4608	Belongs to the ABC transporter superfamily
MID13_23690	COG1444	tRNA N-acetyltransferase activity
MID13_23715	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
MID13_23720	COG0732	type I restriction modification DNA specificity domain