locus-tag	class	description
CU052_00155	ENOG4105W5Q	DNA repair protein (RadC
CU052_00160	ENOG410636K	Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage (By similarity)
CU052_00380	ENOG410607W	Transposase
CU052_00390	ENOG410607W	Transposase
CU052_00410	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
CU052_00415	ENOG4105W49	UPF0434 protein
CU052_00420	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
CU052_00425	ENOG4105BZ1	(ABC) transporter
CU052_00440	ENOG4108EC8	DNA internalization-related competence protein ComEC
CU052_00450	ENOG4105D60	lipoprotein releasing system transmembrane protein
CU052_00455	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CU052_00460	ENOG4105D60	lipoprotein releasing system transmembrane protein
CU052_00470	ENOG4108JA2	transcriptioN-repair coupling factor
CU052_00485	ENOG4105CEP	NADH dehydrogenase
CU052_00490	ENOG4105D0Y	UPF0227 protein
CU052_00515	ENOG4105K59	histidine triad (HIT) protein
CU052_00520	ENOG4108NVR	Methyl-accepting chemotaxis
CU052_00530	ENOG4107SXA	Phosphorylase
CU052_00535	ENOG4105C59	p-type ATPase
CU052_00545	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CU052_00550	ENOG4105DZ0	fad dependent oxidoreductase
CU052_00555	ENOG4108Z4U	Ferredoxin
CU052_00575	ENOG4105BZU	Histidine kinase
CU052_00590	ENOG4108MNP	Glycoprotein polysaccharide metabolism
CU052_00595	ENOG4105C29	acyl-CoA thioesterase
CU052_00605	ENOG4108XM1	transcriptional regulator AsnC family
CU052_00735	ENOG4105BZS	acriflavin resistance protein
CU052_00790	ENOG4105HMI	Membrane
CU052_00810	ENOG4105CI1	PTS System
CU052_00815	ENOG4105CEY	Amp-dependent synthetase and ligase
CU052_00820	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
CU052_00825	ENOG4108IPT	Naphthoate synthase
CU052_00830	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
CU052_00835	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
CU052_00840	ENOG4105E4F	Isochorismate synthase
CU052_00845	ENOG4105CHM	Aminotransferase
CU052_00850	ENOG4105DK2	UPF0207 protein
CU052_00875	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CU052_00920	ENOG4108A04	Beta-lactamase
CU052_00940	ENOG4105C19	ABC transporter
CU052_00945	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
CU052_00960	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
CU052_01000	ENOG4105X96	Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Activated D-alanyl-Dcp donates its D-alanyl substituent to membrane-associated LTA (By similarity)
CU052_01005	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CU052_01015	ENOG4105C0W	non-ribosomal peptide synthetase
CU052_01025	ENOG4105DK2	UPF0207 protein
CU052_01060	ENOG4105EIN	peptidylprolyl cis-trans isomerase
CU052_01065	ENOG4105K70	DNA-binding protein
CU052_01070	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
CU052_01075	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CU052_01080	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
CU052_01085	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CU052_01090	ENOG4105CQZ	Histidine kinase
CU052_01095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CU052_01105	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CU052_01110	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
CU052_01115	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CU052_01120	ENOG4105CNG	UPF0061 protein
CU052_01135	ENOG4107ZYR	domain protein
CU052_01140	ENOG4105C1J	atp-dependent rna helicase
CU052_01150	ENOG4105D05	Receptor
CU052_01165	ENOG4105CEY	Amp-dependent synthetase and ligase
CU052_01165	ENOG4105CEY	Amp-dependent synthetase and ligase
CU052_01170	ENOG4105WQI	isochorismatase
CU052_01175	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
CU052_01180	ENOG4105E4F	Isochorismate synthase
CU052_01190	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
CU052_01230	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CU052_01250	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CU052_01255	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
CU052_01260	ENOG4105C84	Histidine ammonia-lyase
CU052_01290	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CU052_01295	ENOG4105C2D	reductase
CU052_01300	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CU052_01315	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
CU052_01325	ENOG4105DVF	Cytosine-specific methyltransferase
CU052_01330	ENOG4105D9N	nucleoside
CU052_01335	ENOG4105EQ2	LysR family Transcriptional regulator
CU052_01340	ENOG4105CVE	Lytic murein transglycosylase
CU052_01345	ENOG4105VNG	YcgL domain-containing protein
CU052_01350	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CU052_01355	ENOG4107QMS	site-determining protein
CU052_01360	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
CU052_01365	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
CU052_01370	ENOG4105CEY	Amp-dependent synthetase and ligase
CU052_01375	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CU052_01380	ENOG4105R8X	Outer membrane lipoprotein Slp
CU052_01390	ENOG41072GX	Peptidase M22 Glycoprotease
CU052_01395	ENOG4105DVT	helicase
CU052_01400	ENOG4105CIY	formyltetrahydrofolate deformylase
CU052_01405	ENOG4106ZCM	YecM protein
CU052_01415	ENOG4105C75	arginyL-tRNA synthetase
CU052_01435	ENOG4105XFK	Ferrous iron transport protein A
CU052_01440	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
CU052_01445	ENOG4105NXV	High-affinity zinc uptake system protein
CU052_01450	ENOG4105FDK	ABC transporter
CU052_01455	ENOG4105FAV	ABC, transporter
CU052_01460	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
CU052_01465	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
CU052_01470	ENOG4105C7S	Dehydrogenase
CU052_01475	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
CU052_01480	ENOG4105E33	succinate dehydrogenase
CU052_01485	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CU052_01490	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
CU052_01495	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
CU052_01500	ENOG4105BZN	citrate synthase
CU052_01505	ENOG4107QNR	UPF0135 protein
CU052_01520	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
CU052_01525	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
CU052_01530	ENOG4105EV9	Alpha Beta Hydrolase
CU052_01540	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
CU052_01550	ENOG41090R7	Ferric uptake
CU052_01555	ENOG4105X0D	Fimbrial protein
CU052_01560	ENOG4105CX6	glutaminyL-tRNA synthetase
CU052_01565	ENOG4105CI1	PTS System
CU052_01575	ENOG4105CE4	GlcNAc 6-P deacetylase
CU052_01580	ENOG4105E2R	ROK family
CU052_01585	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
CU052_01590	ENOG4105CAQ	asparagine synthetase
CU052_01595	ENOG4105MDZ	Transcriptional activator rfaH
CU052_01605	ENOG4105DUX	Transporter
CU052_01610	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
CU052_01615	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CU052_01620	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CU052_01625	ENOG4108DQ1	activator toxR
CU052_01645	ENOG4108RE9	Phosphodiesterase
CU052_01675	ENOG4105ECP	epimerase
CU052_01680	ENOG4105E1F	short-chain dehydrogenase reductase
CU052_01690	ENOG4107QR8	Thioredoxin
CU052_01695	ENOG4107QX8	SPFH domain, Band 7 family protein
CU052_01730	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CU052_01740	ENOG4105EXN	Sulfate transport protein CysZ
CU052_01745	ENOG4105C6T	cysteine synthase
CU052_01755	ENOG4105KZ7	phosphocarrier protein hpr
CU052_01760	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CU052_01765	ENOG4105C5Y	PTS System
CU052_01775	ENOG4105I03	Flagellin
CU052_01780	ENOG4105I03	Flagellin
CU052_01795	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CU052_01800	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CU052_01805	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CU052_01810	ENOG4105CGA	flagellar basal-body rod protein FlgG
CU052_01815	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CU052_01825	ENOG4105BZE	flagellar hook protein, FlgE
CU052_01830	ENOG4105W00	Flagellar hook capping protein
CU052_01835	ENOG4108ZC9	flagellar basal-body rod protein flgc
CU052_01840	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CU052_01845	ENOG4105BZU	Histidine kinase
CU052_01850	ENOG4107R88	Chemotaxis protein (CheV)
CU052_01895	ENOG4105UYK	outer membrane protein a
CU052_01900	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
CU052_01910	ENOG41081QG	Porin Gram-negative type
CU052_01920	ENOG4105C59	p-type ATPase
CU052_01935	ENOG4105E2D	ec 3.2.1.52
CU052_01965	ENOG4108DG9	Smr protein MutS2
CU052_01970	ENOG4105FE9	pseudouridine synthase
CU052_01975	ENOG4108Z66	YbaK ebsC protein
CU052_01980	ENOG4105CGH	5'-nucleotidase
CU052_01985	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
CU052_01990	ENOG41063JG	Transcriptional regulator
CU052_01995	ENOG4108YY7	Invasion gene expression up-regulator SirB
CU052_02000	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CU052_02005	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CU052_02010	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
CU052_02020	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CU052_02025	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CU052_02030	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CU052_02035	ENOG4105C3G	gtp-binding protein
CU052_02140	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CU052_02150	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CU052_02155	ENOG4105C9A	Phoh family
CU052_02160	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CU052_02165	ENOG4108JU5	Magnesium and cobalt efflux protein
CU052_02170	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
CU052_02175	ENOG4107PAI	alpha helical protein
CU052_02180	ENOG4105C8T	Leucyl-tRNA synthetase
CU052_02185	ENOG4108U2H	Rare lipoprotein B
CU052_02190	ENOG4105DJF	DNA polymerase III, delta' subunit
CU052_02195	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
CU052_02200	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CU052_02205	ENOG4105CJN	penicillin-binding protein
CU052_02210	ENOG4105CNI	cell division protein FtsW
CU052_02215	ENOG4105K6T	rare lipoprotein A
CU052_02220	ENOG4105DZ1	carboxypeptidase
CU052_02225	ENOG4108Z43	UPF0250 protein
CU052_02230	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
CU052_02235	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CU052_02240	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CU052_02245	ENOG4108JYZ	YitT family
CU052_02260	ENOG4105CG3	alpha amylase, catalytic region
CU052_02265	ENOG4105C5Y	PTS System
CU052_02270	ENOG4105D4X	repressor
CU052_02275	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
CU052_02280	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CU052_02285	ENOG4108UMI	ABC transporter, permease
CU052_02290	ENOG4105D01	(LipO)protein
CU052_02300	ENOG4105CGH	5'-nucleotidase
CU052_02305	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
CU052_02310	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
CU052_02315	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
CU052_02325	ENOG4105BZU	Histidine kinase
CU052_02330	ENOG4105EWT	decarboxylase family
CU052_02335	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
CU052_02345	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
CU052_02350	ENOG4105M08	Membrane
CU052_02360	ENOG4105ETT	transcriptional Regulator, LysR family
CU052_02365	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
CU052_02370	ENOG4106VK6	Flagellar motor protein
CU052_02370	ENOG4106VK6	Flagellar motor protein
CU052_02375	ENOG4105E14	MotA TolQ exbB proton channel
CU052_02380	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CU052_02385	ENOG4105CTB	Polyprenyl synthetase
CU052_02390	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CU052_02395	ENOG4108ZAI	phosphatidylglycerophosphatase a
CU052_02400	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
CU052_02405	ENOG4107YIM	Involved in the transcription termination process (By similarity)
CU052_02410	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CU052_02425	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CU052_02430	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CU052_02435	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CU052_02440	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CU052_02445	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
CU052_02450	ENOG4108DJV	Fermentation respiration switch protein
CU052_02455	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
CU052_02460	ENOG4105C7N	Xanthine uracil vitamin C permease
CU052_02465	ENOG4105CIN	aminoacyl-histidine dipeptidase
CU052_02495	ENOG4108ETH	Formylglycinamide ribotide synthetase
CU052_02500	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
CU052_02510	ENOG4108Z6B	deaminase
CU052_02515	ENOG4105CFC	Transporter
CU052_02555	ENOG4105CFG	Acts as a chaperone (By similarity)
CU052_02565	ENOG4105CK2	sodium dicarboxylate symporter
CU052_02570	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CU052_02575	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CU052_02585	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CU052_02590	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CU052_02595	ENOG4105VDB	UPF0125 protein
CU052_02600	ENOG4108Z1B	Cyclase dehydrase
CU052_02605	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CU052_02615	ENOG4105DFP	Integrase
CU052_02655	ENOG4108YGG	dna repair protein
CU052_02680	ENOG4105VW4	glutaredoxin 3
CU052_02695	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CU052_02720	ENOG4105CT5	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate (By similarity)
CU052_02750	ENOG4105ETT	transcriptional Regulator, LysR family
CU052_02755	ENOG410613R	integral membrane protein, YccS YhfK family
CU052_02775	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CU052_02795	ENOG4105JRK	feS assembly protein SufD
CU052_02800	ENOG4105C3K	feS assembly ATPase SufC
CU052_02805	ENOG4105DIW	FeS assembly protein SUFB
CU052_02810	ENOG4108Z4V	iron-sulfur cluster assembly
CU052_02815	ENOG4108IQK	o-acetylhomoserine
CU052_02820	ENOG4105D64	Mechanosensitive ion channel
CU052_02825	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
CU052_02830	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CU052_02835	ENOG4105BZG	amino acid carrier protein
CU052_02840	ENOG4106HK8	GPR1 FUN34 yaaH family protein
CU052_02850	ENOG4107S6Z	Na H antiporter
CU052_02855	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CU052_02860	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CU052_02865	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CU052_02875	ENOG410620I	Diguanylate cyclase
CU052_02885	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
CU052_02890	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CU052_02895	ENOG4105N21	Membrane
CU052_02900	ENOG4105CUT	histidyl-tRNA synthetase
CU052_02905	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CU052_02915	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CU052_02920	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CU052_02925	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CU052_02930	ENOG4105WVQ	Fe-S assembly protein IscX
CU052_02935	ENOG4108ZIT	Ferredoxin, 2FE-2S
CU052_02940	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
CU052_02945	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
CU052_02950	ENOG4108Z4V	iron-sulfur cluster assembly
CU052_02955	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
CU052_02960	ENOG4105C3J	Cysteine desulfurase
CU052_02965	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
CU052_02970	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
CU052_02975	ENOG4105ECY	inositol monophosphatase
CU052_02990	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CU052_02995	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CU052_03000	ENOG4105VIE	preprotein translocase, subunit YajC
CU052_03005	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CU052_03010	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CU052_03025	ENOG4105W87	Cbs domain
CU052_03030	ENOG4108I9X	Isocitrate lyase
CU052_03035	ENOG4107QP3	malate synthase g
CU052_03040	ENOG4105C5Q	Transcriptional regulator
CU052_03045	ENOG4105D3R	alkyl hydroperoxide reductase
CU052_03050	ENOG4106N3A	copper homeostasis protein cutc
CU052_03055	ENOG4105CSR	polyphosphate kinase 2
CU052_03080	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CU052_03085	ENOG4105E2Z	phosphate ABC transporter (Permease
CU052_03090	ENOG4105C8U	phosphate abc transporter
CU052_03095	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
CU052_03100	ENOG4105C9X	ppx gppa phosphatase
CU052_03110	ENOG4105BZU	Histidine kinase
CU052_03115	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CU052_03120	ENOG4105DH7	May be involved in recombination (By similarity)
CU052_03125	ENOG4105CFP	Peptidase U32
CU052_03130	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
CU052_03140	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
CU052_03200	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CU052_03205	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
CU052_03210	ENOG4105C34	Pseudouridine synthase
CU052_03215	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CU052_03220	ENOG4105E4C	Lytic transglycosylase catalytic
CU052_03225	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
CU052_03235	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CU052_03240	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
CU052_03245	ENOG4107SC1	transglycosylase
CU052_03250	ENOG4105C5H	ABC transporter
CU052_03260	ENOG4105DR5	peptidase
CU052_03265	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
CU052_03270	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CU052_03275	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
CU052_03280	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
CU052_03295	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CU052_03315	ENOG4108HRK	Histidine kinase
CU052_03320	ENOG4108NEV	two component transcriptional regulator, LytTR family
CU052_03325	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
CU052_03330	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
CU052_03335	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CU052_03340	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CU052_03345	ENOG4105DTN	riboflavin biosynthesis protein ribF
CU052_03350	ENOG4105CJR	Integral membrane protein (MviN
CU052_03355	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CU052_03360	ENOG41080HT	Transcriptional regulator, arsr family
CU052_03365	ENOG41063Z6	transcriptional regulator, lysR family
CU052_03375	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CU052_03380	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CU052_03385	ENOG4105HF0	Membrane
CU052_03390	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
CU052_03395	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
CU052_03400	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
CU052_03410	ENOG4105CPC	Aldo Keto reductase
CU052_03420	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CU052_03425	ENOG4105CRK	lysyL-tRNA synthetase
CU052_03435	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CU052_03440	ENOG4105T95	Thiol disulfide interChange protein
CU052_03445	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CU052_03450	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
CU052_03455	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
CU052_03460	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
CU052_03465	ENOG4105C1J	atp-dependent rna helicase
CU052_03475	ENOG4105D1Q	UPF0246 protein
CU052_03480	ENOG4105BZG	amino acid carrier protein
CU052_03495	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
CU052_03505	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
CU052_03510	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
CU052_03515	ENOG4108YYH	Nadph-dependent fmn reductase
CU052_03520	ENOG4105D98	threonine synthase
CU052_03525	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CU052_03540	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CU052_03555	ENOG41065U4	response regulator
CU052_03565	ENOG4105BZU	Histidine kinase
CU052_03605	ENOG4105CBC	glutamate synthase
CU052_03610	ENOG4105BZ8	glutamate synthase
CU052_03620	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CU052_03630	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
CU052_03635	ENOG4105EN6	Membrane
CU052_03640	ENOG4105VP0	transcriptional regulator, lysR family
CU052_03645	ENOG4105EJ9	Membrane
CU052_03665	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CU052_03670	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CU052_03675	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CU052_03680	ENOG4105M6F	mutator MutT protein
CU052_03685	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CU052_03690	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CU052_03695	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CU052_03700	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
CU052_03705	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
CU052_03710	ENOG4105DFU	Cell wall formation (By similarity)
CU052_03715	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CU052_03725	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CU052_03730	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CU052_03735	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
CU052_03740	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
CU052_03745	ENOG4105CJN	penicillin-binding protein
CU052_03750	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CU052_03755	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CU052_03770	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CU052_03780	ENOG41082RQ	UPF0102 protein
CU052_03785	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CU052_03790	ENOG4105W4M	Transport-associated protein
CU052_03795	ENOG4105KB2	stringent starvation protein b
CU052_03800	ENOG4107MKT	Stringent starvation protein a
CU052_03805	ENOG4105EIX	cytochrome c1
CU052_03810	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CU052_03815	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
CU052_03820	ENOG4108UJD	30S ribosomal protein S9
CU052_03825	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CU052_03835	ENOG4105D6Z	AFG1 family ATPase
CU052_03845	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
CU052_03855	ENOG4105C0H	protease
CU052_03860	ENOG4105C0H	protease
CU052_03865	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CU052_03870	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CU052_03875	ENOG4105IPS	esterase
CU052_03880	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
CU052_03885	ENOG4108SX3	cytoplasmic protein
CU052_03890	ENOG41087AY	ADP-Ribose pyrophosphatase
CU052_03895	ENOG4105DFG	type I secretion outer membrane protein
CU052_03900	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
CU052_03905	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
CU052_03910	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_03920	ENOG4105I7R	Adenylate cyclase
CU052_03925	ENOG4107IX6	phosphate transport regulator
CU052_03930	ENOG4105CJ3	phosphate transporter
CU052_03935	ENOG4106MWK	domain protein
CU052_03950	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CU052_03955	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CU052_03960	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CU052_03965	ENOG4107ZVW	dihydroneopterin aldolase
CU052_03970	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CU052_03975	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
CU052_03980	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CU052_03985	ENOG4105VCC	30S ribosomal protein S21
CU052_03990	ENOG4105KTH	gatB Yqey
CU052_03995	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CU052_04000	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CU052_04030	ENOG4105CTS	PTS system mannitol-specific
CU052_04035	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
CU052_04040	ENOG4105E61	Mannitol repressor protein
CU052_04045	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CU052_04050	ENOG4105GR3	Histidine kinase
CU052_04070	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CU052_04075	ENOG410804X	Transcriptional regulator
CU052_04085	ENOG4105CA9	Pyruvate kinase
CU052_04100	ENOG4108ZP8	Acetolactate synthase small subunit
CU052_04105	ENOG4105C7K	acetolactate synthase
CU052_04110	ENOG4108IQE	Amp-dependent synthetase and ligase
CU052_04115	ENOG41064T2	transcriptional regulator, lysR family
CU052_04140	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CU052_04145	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CU052_04150	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CU052_04155	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CU052_04165	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
CU052_04170	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
CU052_04175	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
CU052_04180	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
CU052_04185	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CU052_04190	ENOG4105NWN	ApaG protein
CU052_04195	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
CU052_04205	ENOG4107XM3	UPF0442 protein
CU052_04210	ENOG4105DWK	Membrane
CU052_04215	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CU052_04220	ENOG4105K46	50S ribosomal protein l27
CU052_04225	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
CU052_04230	ENOG4105EAH	synthase
CU052_04240	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CU052_04245	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
CU052_04270	ENOG4107T0D	ABC, transporter
CU052_04275	ENOG4106SMU	thiamine transporter membrane protein
CU052_04280	ENOG4105DP9	ABC transporter
CU052_04285	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
CU052_04290	ENOG4105DFU	Cell wall formation (By similarity)
CU052_04295	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CU052_04300	ENOG4105F0N	pyrophosphate phospho-hydrolase
CU052_04310	ENOG41066HZ	AIG2-like family
CU052_04320	ENOG4105CFU	surface antigen
CU052_04325	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CU052_04335	ENOG4108UUE	Transcriptional regulator
CU052_04350	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CU052_04370	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
CU052_04380	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
CU052_04385	ENOG4105C11	sulfate adenylyltransferase), subunit 2
CU052_04390	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CU052_04395	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
CU052_04405	ENOG4105C1J	atp-dependent rna helicase
CU052_04410	ENOG4107YB6	acetyltransferase, (GNAT) family
CU052_04425	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CU052_04435	ENOG4108ZT0	50S ribosomal protein l17
CU052_04440	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CU052_04445	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CU052_04450	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CU052_04455	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CU052_04465	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CU052_04470	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CU052_04475	ENOG4105VPB	50S ribosomal protein L30
CU052_04480	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CU052_04490	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CU052_04495	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CU052_04500	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CU052_04505	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CU052_04510	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CU052_04515	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CU052_04520	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CU052_04525	ENOG41083MP	50s ribosomal protein l29
CU052_04530	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CU052_04535	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
CU052_04540	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CU052_04545	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
CU052_04550	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CU052_04555	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CU052_04560	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CU052_04565	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
CU052_04570	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CU052_04575	ENOG4105VFB	Binds the 23S rRNA (By similarity)
CU052_04585	ENOG4105C25	Primosomal protein n'
CU052_04590	ENOG4105ETE	Transcriptional regulator (LacI family
CU052_04600	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
CU052_04605	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
CU052_04615	ENOG4108YGG	dna repair protein
CU052_04650	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
CU052_04655	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
CU052_04660	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
CU052_04665	ENOG4105CBT	Fructose-1,6-bisphosphatase
CU052_04695	ENOG4105CP7	Triose-phosphate isomerase
CU052_04705	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CU052_04720	ENOG4105ESV	Glycosyl transferase, family 4
CU052_04760	ENOG4105DSJ	YicC domain protein
CU052_04765	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CU052_04770	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
CU052_04775	ENOG4105D1S	lipid A biosynthesis
CU052_04780	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
CU052_04785	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CU052_04795	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_04800	ENOG4105W5Q	DNA repair protein (RadC
CU052_04805	ENOG4105KDC	50s ribosomal protein l28
CU052_04815	ENOG4108I6E	Sulfatase
CU052_04825	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
CU052_04830	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CU052_04835	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
CU052_04845	ENOG4106WTF	Glycosyl transferase, family 2
CU052_04850	ENOG4105DKP	glycosyl transferase, family 9
CU052_04855	ENOG41080IJ	Diacylglycerol kinase
CU052_04860	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
CU052_04865	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
CU052_04900	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
CU052_04905	ENOG4105XA0	heptosyltransferase ii
CU052_04910	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
CU052_04915	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
CU052_04920	ENOG4105E3R	(LipO)protein
CU052_04955	ENOG4105F0R	Cytidylyltransferase
CU052_04965	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
CU052_04985	ENOG41068D6	Glycosyltransferase
CU052_05030	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CU052_05060	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CU052_05070	ENOG4105DWP	Membrane
CU052_05085	ENOG4108JQ7	(ABC) transporter
CU052_05095	ENOG4107QRA	Extracellular solute-binding protein, family 5
CU052_05100	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
CU052_05135	ENOG4109015	Biopolymer transport protein exbD tolR
CU052_05150	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CU052_05155	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
CU052_05160	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CU052_05165	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
CU052_05170	ENOG4105CB5	ATP-dependent DNA helicase recG
CU052_05180	ENOG4105C2W	permease
CU052_05185	ENOG4105E0F	Histidine kinase
CU052_05190	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CU052_05195	ENOG4108RRZ	Transcription elongation factor GreB
CU052_05205	ENOG4105BZM	domain protein
CU052_05215	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
CU052_05220	ENOG4105MJ2	Competence protein
CU052_05225	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
CU052_05230	ENOG4107RK2	ADP-ribose diphosphatase NudE
CU052_05235	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
CU052_05240	ENOG4105PIC	general secretion pathway protein N
CU052_05245	ENOG4105U1E	general secretion pathway protein M
CU052_05250	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
CU052_05255	ENOG4108RTD	type II secretion system protein K
CU052_05260	ENOG4108WWZ	General secretion pathway protein J
CU052_05265	ENOG4105X5Z	General secretion pathway protein I
CU052_05270	ENOG4105VWV	general secretion pathway protein h
CU052_05275	ENOG4108VAU	general secretion pathway protein G
CU052_05280	ENOG4105D7Q	type ii secretion system
CU052_05285	ENOG4107QHF	type ii secretion system protein e
CU052_05295	ENOG4108XKW	General secretion pathway protein C
CU052_05300	ENOG4105VEJ	Heat shock protein
CU052_05305	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CU052_05310	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
CU052_05320	ENOG4105SUU	thioesterase domain
CU052_05325	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CU052_05330	ENOG4107S2Z	UPF0761 membrane protein
CU052_05355	ENOG4105C5F	glutamine synthetase
CU052_05365	ENOG4105CUX	Signal transduction histidine kinase
CU052_05370	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CU052_05375	ENOG4105BZU	Histidine kinase
CU052_05380	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CU052_05385	ENOG4105D4P	Coproporphyrinogen iii oxidase
CU052_05395	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
CU052_05410	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CU052_05420	ENOG4105C2M	dna polymerase I
CU052_05435	ENOG4105D52	delta-aminolevulinic acid dehydratase
CU052_05440	ENOG4105F8V	Hydrolase, tatD family
CU052_05445	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
CU052_05450	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
CU052_05455	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
CU052_05460	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CU052_05465	ENOG4105JC1	sterol-binding domain protein
CU052_05475	ENOG4105CGY	Dna recombination protein
CU052_05485	ENOG4105BZU	Histidine kinase
CU052_05495	ENOG4105CBX	hi0933 family
CU052_05500	ENOG4108V6B	universal stress protein B
CU052_05505	ENOG41090A1	ferritin
CU052_05515	ENOG4108M6U	Universal stress protein A
CU052_05520	ENOG4105EMK	carboxylate amino acid amine transporter
CU052_05535	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
CU052_05540	ENOG4105BZU	Histidine kinase
CU052_05545	ENOG4108VVK	transcriptional Regulator, AsnC
CU052_05550	ENOG4105DGW	oligopeptidase A
CU052_05560	ENOG4105D6S	protein involved in catabolism of external DNA
CU052_05570	ENOG4105DC8	reductase
CU052_05585	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CU052_05605	ENOG4108UHU	Aldolase
CU052_05610	ENOG4105C6Z	Gluconate
CU052_05615	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
CU052_05620	ENOG4105C01	Dihydroxy-acid dehydratase
CU052_05635	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
CU052_05640	ENOG41064T2	transcriptional regulator, lysR family
CU052_05645	ENOG4105DIQ	Transcriptional regulator
CU052_05680	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU052_05685	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CU052_05690	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU052_05695	ENOG4108JQ6	ABC transporter
CU052_05735	ENOG4105MPD	Cytochrome
CU052_05740	ENOG4105C4R	Atp-dependent dna helicase
CU052_05745	ENOG4107Z3H	Transcriptional regulator, TetR family
CU052_05750	ENOG410624X	efflux transporter, rnd family, mfp subunit
CU052_05755	ENOG4105BZS	acriflavin resistance protein
CU052_05765	ENOG4105W0Z	cytoplasmic protein
CU052_05770	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CU052_05775	ENOG4105EMY	transcriptional regulator
CU052_05825	ENOG4108RR8	protoporphyrinogen oxidase
CU052_05830	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CU052_05835	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CU052_05840	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CU052_05845	ENOG4105CHU	acetyl-coa acetyltransferase
CU052_05850	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
CU052_05865	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CU052_05880	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
CU052_05885	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
CU052_05890	ENOG4107T9C	Alpha amylase catalytic region
CU052_05895	ENOG4105JKW	Valine--pyruvate aminotransferase
CU052_05900	ENOG4108ZNX	Heat shock protein
CU052_05905	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CU052_05910	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CU052_05915	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CU052_05920	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CU052_05930	ENOG4105EAB	amino acid AbC transporter
CU052_05935	ENOG4105E5Q	amino acid AbC transporter
CU052_05950	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
CU052_05955	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CU052_05960	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CU052_05965	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CU052_05970	ENOG4105QTB	Flavodoxin
CU052_05975	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CU052_05980	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CU052_05985	ENOG4107QJE	Chromosome Partitioning Protein
CU052_05990	ENOG4105FA0	parb-like partition protein
CU052_05995	ENOG410684E	atp synthase
CU052_06000	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
CU052_06005	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CU052_06010	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CU052_06015	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CU052_06020	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CU052_06025	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CU052_06030	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CU052_06035	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CU052_06040	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CU052_06045	ENOG4105EAD	ABC transporter
CU052_06050	ENOG4105F87	Dehydratase
CU052_06055	ENOG4105CZQ	inner membrane transport protein YdhC
CU052_06060	ENOG4105F52	Transcriptional regulator
CU052_06065	ENOG4105C7B	Threonine dehydratase
CU052_06070	ENOG4105C01	Dihydroxy-acid dehydratase
CU052_06075	ENOG4105CM2	brancheD-chain amino acid aminotransferase
CU052_06080	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
CU052_06095	ENOG4105EXC	Acyl-transferase
CU052_06110	ENOG4106PHI	plasmid recombination enzyme
CU052_06125	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CU052_06195	ENOG4105EQR	Transposase IS116 IS110 IS902
CU052_06235	ENOG4105BZU	Histidine kinase
CU052_06245	ENOG4106HNH	Acyl-transferase
CU052_06250	ENOG4108Z33	Thiol disulfide Interchange Protein
CU052_06255	ENOG4105E27	serine threonine protein kinase
CU052_06265	ENOG4105PC1	Conserved Protein
CU052_06275	ENOG4108N23	SpoOM-related protein
CU052_06280	ENOG4108UT2	hemolysin iii
CU052_06290	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CU052_06295	ENOG4105C1A	potassium transporter peripheral membrane
CU052_06300	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CU052_06305	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CU052_06320	ENOG4105C79	DNA protecting protein DprA
CU052_06325	ENOG4108RPN	Protein smg homolog
CU052_06330	ENOG4108WI1	Dna topoisomerase
CU052_06335	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
CU052_06340	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CU052_06345	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CU052_06350	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
CU052_06355	ENOG4105E2X	shikimate dehydrogenase
CU052_06365	ENOG4108Z0R	Transferase
CU052_06415	ENOG4105E3B	Multicopper oxidase
CU052_06420	ENOG4105WMR	Protein CrcB homolog
CU052_06425	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CU052_06435	ENOG4105D06	uba thif-type nad fad binding protein
CU052_06440	ENOG4105WHD	thiamine biosynthesis protein ThiS
CU052_06445	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CU052_06450	ENOG4105D41	biosynthesis protein thiH
CU052_06455	ENOG4105DC7	peptidase M24
CU052_06455	ENOG4105DC7	peptidase M24
CU052_06460	ENOG4105G2Y	Transcriptional regulator
CU052_06465	ENOG4105CNH	Multidrug resistance protein MdtL
CU052_06485	ENOG4105E18	UPF0276 protein
CU052_06495	ENOG4105C4R	Atp-dependent dna helicase
CU052_06505	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
CU052_06520	ENOG4105FR1	rard protein
CU052_06525	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CU052_06540	ENOG4105EX9	Membrane
CU052_06545	ENOG4105C9X	ppx gppa phosphatase
CU052_06550	ENOG4105C1J	atp-dependent rna helicase
CU052_06555	ENOG4105K63	Thioredoxin
CU052_06560	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CU052_06570	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
CU052_06575	ENOG4108ZIT	Ferredoxin, 2FE-2S
CU052_06580	ENOG4107QK7	reductase
CU052_06615	ENOG410601J	HemY protein
CU052_06620	ENOG4105ECF	c-methyltransferase
CU052_06625	ENOG41076E6	Uroporphyrinogen-III Synthase
CU052_06630	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
CU052_06635	ENOG4107T0K	Adenylate cyclase
CU052_06640	ENOG4105XQ6	frataxin-like protein
CU052_06650	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CU052_06655	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CU052_06665	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CU052_06670	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
CU052_06680	ENOG4106IUH	DTW domain containing protein
CU052_06695	ENOG4105DQF	Hydrolase
CU052_06700	ENOG4108EUD	Lysophospholipase
CU052_06705	ENOG410829K	Lysine exporter protein (Lyse ygga)
CU052_06710	ENOG4105D58	Diguanylate phosphodiesterase
CU052_06715	ENOG41082YX	Transcriptional regulator, arsr family
CU052_06720	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CU052_06770	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
CU052_06780	ENOG4106H78	methyltransferase
CU052_06785	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CU052_06785	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CU052_06790	ENOG4105CAK	Cell division ATP-binding protein ftsE
CU052_06795	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CU052_06800	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CU052_06805	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CU052_06810	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
CU052_06815	ENOG4105X6C	Flagellar basal body-associated protein FliL
CU052_06820	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
CU052_06825	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
CU052_06830	ENOG4105E55	glycerol-3-phosphate acyltransferase
CU052_06840	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CU052_06850	ENOG4107R73	Mate efflux family protein
CU052_06855	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
CU052_06870	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
CU052_06875	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CU052_06885	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CU052_06975	ENOG4105JIM	Phosphatidylserine synthase
CU052_06985	ENOG4105D4A	Cell wall formation (By similarity)
CU052_06990	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CU052_06995	ENOG4105CS9	pantothenic acid kinase
CU052_07020	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CU052_07030	ENOG4105PM1	preprotein translocase subunit SecE
CU052_07035	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CU052_07040	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
CU052_07045	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CU052_07050	ENOG4108VZM	50s ribosomal protein L10
CU052_07055	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CU052_07060	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CU052_07065	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CU052_07070	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
CU052_07075	ENOG4105E09	nadh pyrophosphatase
CU052_07090	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
CU052_07095	ENOG4108RG0	uracil-dna glycosylase
CU052_07100	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
CU052_07105	ENOG4105R2J	Conserved Protein
CU052_07125	ENOG4105C12	Phosphoribosylglycinamide synthetase
CU052_07130	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CU052_07140	ENOG4105W1Y	Transcriptional regulator
CU052_07145	ENOG4108M3R	transcriptional activator CadC
CU052_07155	ENOG4105D5Q	Arginine ornithine antiporter
CU052_07160	ENOG4105CXN	decarboxylase
CU052_07195	ENOG4105BZU	Histidine kinase
CU052_07200	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
CU052_07205	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CU052_07210	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
CU052_07220	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CU052_07225	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CU052_07230	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CU052_07235	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CU052_07250	ENOG4105D8G	Major Facilitator superfamily
CU052_07255	ENOG4105BZU	Histidine kinase
CU052_07260	ENOG4105C9Q	fumarate hydratase class II
CU052_07285	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CU052_07295	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CU052_07300	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CU052_07305	ENOG4108IJ0	Aspartate ammonia-lyase
CU052_07315	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
CU052_07325	ENOG4105E0F	Histidine kinase
CU052_07330	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CU052_07335	ENOG4108SPG	Periplasmic Protein
CU052_07340	ENOG41076HS	cation diffusion facilitator family transporter
CU052_07345	ENOG4105CTQ	phosphohexokinase
CU052_07350	ENOG4107QI1	Mate efflux family protein
CU052_07355	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CU052_07360	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CU052_07375	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
CU052_07380	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CU052_07395	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CU052_07400	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
CU052_07415	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
CU052_07425	ENOG41062JF	Transcriptional regulator
CU052_07435	ENOG41063SB	peptidase
CU052_07440	ENOG4105D7W	serine acetyltransferase
CU052_07445	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CU052_07450	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
CU052_07455	ENOG4107YZP	Rhodanese domain protein
CU052_07460	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CU052_07470	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_07475	ENOG4105C8P	)-transporter
CU052_07480	ENOG4105DJ4	phosphatidylserine decarboxylase
CU052_07485	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CU052_07490	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
CU052_07555	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
CU052_07560	ENOG4105K8N	protein family UPF0079, ATPase
CU052_07565	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CU052_07570	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
CU052_07575	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CU052_07580	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
CU052_07585	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CU052_07590	ENOG4107QJR	hflk protein
CU052_07595	ENOG4105EPW	hflc protein
CU052_07605	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CU052_07615	ENOG4108UV7	flagellar protein motX
CU052_07620	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CU052_07625	ENOG4105EQR	Transposase IS116 IS110 IS902
CU052_07630	ENOG4105KPV	Transcriptional regulator
CU052_07635	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CU052_07640	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CU052_07645	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CU052_07650	ENOG4105C31	Tryptophanyl-tRNA synthetase
CU052_07670	ENOG4105DDQ	anthranilate synthase
CU052_07675	ENOG4105C8Y	Acetylornithine aminotransferase
CU052_07685	ENOG4105C26	Dehydrogenase
CU052_07695	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
CU052_07700	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
CU052_07705	ENOG4105YP7	UPF0270 protein
CU052_07710	ENOG4105DNZ	Alpha Beta Hydrolase
CU052_07720	ENOG4105C5H	ABC transporter
CU052_07730	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CU052_07745	ENOG4108YZY	peptidylprolyl cis-trans isomerase
CU052_07755	ENOG4105D44	asparaginase
CU052_07760	ENOG41069P5	Protein slyX homolog
CU052_07770	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CU052_07775	ENOG4105WWK	YheO domain protein
CU052_07780	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
CU052_07785	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
CU052_07790	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
CU052_07795	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CU052_07800	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CU052_07805	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CU052_07810	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CU052_07815	ENOG4105W53	bacterioferritin-associated ferredoxin
CU052_07820	ENOG4108UQY	Iron-storage protein
CU052_07825	ENOG4105C6K	Malic enzyme
CU052_07830	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
CU052_07835	ENOG4105C28	cystathionine
CU052_07840	ENOG4105CFH	Aspartokinase
CU052_07845	ENOG4105SYT	Methylenetetrahydrofolate reductase
CU052_07855	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
CU052_07860	ENOG4105CWC	Acetylornithine deacetylase
CU052_07865	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CU052_07870	ENOG4105CAS	nag kinase
CU052_07875	ENOG4105CDH	Citrulline--aspartate ligase
CU052_07880	ENOG4105CH7	arginosuccinase
CU052_07895	ENOG4107QN2	dihydrolipoyl dehydrogenase
CU052_07900	ENOG4105EHV	domain protein
CU052_07905	ENOG4105C5Q	Transcriptional regulator
CU052_07910	ENOG4108JQC	penicillin-binding protein 1A
CU052_07935	ENOG4105E4G	Type IV pilus
CU052_07940	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
CU052_07945	ENOG4105D49	3-dehydroquinate synthase
CU052_07955	ENOG4105DFE	Dna adenine methylase
CU052_07960	ENOG4105DJV	ribulose-phosphate 3-epimerase
CU052_07965	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
CU052_07970	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CU052_07975	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CU052_07985	ENOG4105CDU	Replicative dna helicase
CU052_07990	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CU052_08000	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
CU052_08005	ENOG4107QP8	phosphohexose isomerase
CU052_08015	ENOG4105MYN	Zinc uptake regulation protein
CU052_08020	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CU052_08040	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
CU052_08045	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
CU052_08050	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
CU052_08085	ENOG4105EEQ	Na H antiporter
CU052_08090	ENOG4105C3R	Methionine synthase
CU052_08095	ENOG4105CFH	Aspartokinase
CU052_08105	ENOG4105C5R	Aminotransferase
CU052_08115	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CU052_08120	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
CU052_08125	ENOG41086KC	Transcriptional regulator
CU052_08130	ENOG4108UUM	single-stranded DNA-binding protein
CU052_08135	ENOG41062P1	Diguanylate cyclase phosphodiesterase
CU052_08145	ENOG410607W	Transposase
CU052_08185	ENOG4107QHF	type ii secretion system protein e
CU052_08190	ENOG4105D7Q	type ii secretion system
CU052_08200	ENOG4108VAU	general secretion pathway protein G
CU052_08235	ENOG4105DFF	Rod shape-determining protein mreb
CU052_08240	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CU052_08245	ENOG4105VQ7	Rod shape-determining protein MreD
CU052_08250	ENOG4108Z03	MAF-like protein
CU052_08255	ENOG4105C03	ribonuclease
CU052_08260	ENOG4105QD6	exported protein
CU052_08270	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CU052_08275	ENOG4108IAB	Phoh family
CU052_08280	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
CU052_08285	ENOG4105K3M	)-transporter
CU052_08290	ENOG4105D3G	Pseudouridine synthase
CU052_08295	ENOG4105C5I	Dehydrogenase
CU052_08300	ENOG4105N42	UPF0307 protein
CU052_08305	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
CU052_08310	ENOG4105CJW	magnesium transporter
CU052_08315	ENOG41080Z8	PHOSPHOCARRIER protein
CU052_08320	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CU052_08325	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
CU052_08330	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
CU052_08335	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CU052_08340	ENOG4108IUZ	ABC transporter
CU052_08345	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
CU052_08355	ENOG4105C2X	Arabinose 5-phosphate isomerase
CU052_08365	ENOG4105DHJ	ABC, transporter
CU052_08370	ENOG4105CY3	ABC transporter, permease
CU052_08375	ENOG4107PE3	Mammalian cell entry related domain protein
CU052_08380	ENOG4105E3I	toluene tolerance
CU052_08390	ENOG4105VFK	BolA family
CU052_08395	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CU052_08400	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
CU052_08405	ENOG4105KME	endoribonuclease L-psp
CU052_08410	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
CU052_08415	ENOG4105CXT	aspartate transcarbamylase
CU052_08425	ENOG4105DBV	ornithine carbamoyltransferase
CU052_08430	ENOG4105CEU	Arginine dihydrolase
CU052_08445	ENOG4108MJ3	acetyltransferase
CU052_08455	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CU052_08460	ENOG4105MYG	DNA polymerase iii, chi subunit
CU052_08465	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
CU052_08470	ENOG4108M8S	permease YjgP YjgQ family protein
CU052_08475	ENOG4108K5H	permease YjgP YjgQ family protein
CU052_08485	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
CU052_08505	ENOG4105VZJ	PTS System
CU052_08515	ENOG4105VCP	PTS System
CU052_08520	ENOG4105F8D	glycoside hydrolase family 4
CU052_08525	ENOG410901P	UPF0249 protein
CU052_08535	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CU052_08590	ENOG4105C26	Dehydrogenase
CU052_08620	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_08665	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
CU052_08670	ENOG4105CEN	a g-specific adenine glycosylase
CU052_08675	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CU052_08685	ENOG4105CSV	Glutaminase
CU052_08690	ENOG4105CSA	Coproporphyrinogen iii oxidase
CU052_08695	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
CU052_08705	ENOG4105VZ9	UPF0235 protein
CU052_08710	ENOG4108VIA	integral membrane protein
CU052_08715	ENOG4105II7	pyrroline-5-carboxylate reductase
CU052_08720	ENOG4105DFA	alanine racemase domain protein
CU052_08725	ENOG4105CZX	twitching motility protein
CU052_08730	ENOG4105CZX	twitching motility protein
CU052_08735	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
CU052_08740	ENOG4108UJU	UPF0301 protein
CU052_08745	ENOG4105D7Z	glutathione synthase
CU052_08750	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CU052_08755	ENOG4105RWS	endonuclease I
CU052_08765	ENOG4105GPY	SprT protein
CU052_08775	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CU052_08780	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CU052_08790	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CU052_08795	ENOG4105BZA	Phosphoglycerate kinase
CU052_08800	ENOG4105D2N	Aldolase
CU052_08805	ENOG4105D64	Mechanosensitive ion channel
CU052_08820	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
CU052_08825	ENOG4105MPN	Membrane
CU052_08830	ENOG4108JQ1	Dehydrogenase
CU052_08835	ENOG4105E66	phosphoriboisomerase A
CU052_08840	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
CU052_08850	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
CU052_08865	ENOG4105D0A	hydroxylase
CU052_08870	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
CU052_08885	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
CU052_08890	ENOG4105Y75	tpr repeat protein
CU052_08900	ENOG4108IYU	L-aspartate oxidase
CU052_08910	ENOG4105EMN	RNA polymerase sigma factor
CU052_08930	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CU052_08935	ENOG4105C3F	Signal peptidase i
CU052_08940	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CU052_08945	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CU052_08950	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
CU052_08955	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
CU052_08960	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
CU052_08965	ENOG4105BZU	Histidine kinase
CU052_08975	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CU052_08980	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CU052_08985	ENOG4105DXN	mazG family
CU052_08990	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CU052_09000	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
CU052_09005	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CU052_09010	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CU052_09015	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
CU052_09020	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
CU052_09025	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
CU052_09035	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CU052_09040	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CU052_09045	ENOG4107TH8	cina domain protein
CU052_09050	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CU052_09055	ENOG4105Y3E	Modulates RecA activity (By similarity)
CU052_09060	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CU052_09065	ENOG4105CFH	Aspartokinase
CU052_09070	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CU052_09130	ENOG4107QSA	Oxaloacetate decarboxylase
CU052_09135	ENOG4105D9Q	decarboxylase (Beta subunit)
CU052_09155	ENOG4105D9M	gamma-glutamylcysteine synthetase
CU052_09165	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CU052_09170	ENOG4108JU6	CBS domain protein
CU052_09175	ENOG4106KVJ	cytochrome C assembly protein
CU052_09180	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CU052_09185	ENOG4105K5M	30s ribosomal protein S16
CU052_09190	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CU052_09195	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CU052_09200	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CU052_09210	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
CU052_09215	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CU052_09220	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
CU052_09225	ENOG4105D7Q	type ii secretion system
CU052_09230	ENOG4107QHF	type ii secretion system protein e
CU052_09245	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CU052_09255	ENOG41073TP	transcriptional regulator
CU052_09260	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
CU052_09265	ENOG4107QSN	dihydrolipoamide acetyltransferase
CU052_09270	ENOG4107QN2	dihydrolipoyl dehydrogenase
CU052_09275	ENOG410630P	Transcriptional regulator
CU052_09280	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CU052_09285	ENOG41077A9	carbonic anhydrase
CU052_09290	ENOG4105CHH	sulfate transporter
CU052_09295	ENOG4105DA5	(ABC) transporter
CU052_09300	ENOG4105E3A	(ABC) transporter
CU052_09305	ENOG4105D1S	lipid A biosynthesis
CU052_09310	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CU052_09315	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CU052_09320	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CU052_09325	ENOG4105DJ0	Poly(A) Polymerase
CU052_09335	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
CU052_09340	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CU052_09345	ENOG4105PW4	Sugar fermentation stimulation protein homolog
CU052_09350	ENOG4105CQ7	ATP-dependent helicase
CU052_09355	ENOG4105BZ4	penicillin-binding protein
CU052_09360	ENOG4105D78	K07001 NTE family protein
CU052_09365	ENOG4107QIJ	Aconitate hydratase 2
CU052_09375	ENOG4105XTV	UPF0231 protein
CU052_09380	ENOG4108YZA	Nitrogen regulatory protein pii
CU052_09400	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CU052_09415	ENOG4105E2D	ec 3.2.1.52
CU052_09420	ENOG4105RD7	BadF BadG BcrA BcrD
CU052_09430	ENOG4108JQ7	(ABC) transporter
CU052_09435	ENOG4105C3U	ABC transporter
CU052_09440	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU052_09450	ENOG4105DEF	Extracellular solute-binding protein, family 5
CU052_09455	ENOG4105BZU	Histidine kinase
CU052_09465	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CU052_09470	ENOG4105F4G	Membrane
CU052_09475	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
CU052_09480	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
CU052_09495	ENOG4105DR5	peptidase
CU052_09500	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CU052_09510	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
CU052_09515	ENOG4107QE9	Inherit from COG: Membrane
CU052_09520	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CU052_09525	ENOG4105HBR	Rna-binding protein
CU052_09530	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
CU052_09535	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CU052_09540	ENOG4105EEI	dihydropteroate synthase
CU052_09545	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CU052_09565	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CU052_09570	ENOG4105CHV	Transcription elongation factor NusA
CU052_09575	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CU052_09580	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
CU052_09585	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CU052_09590	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CU052_09595	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CU052_09610	ENOG4105C3S	Mate efflux family protein
CU052_09615	ENOG4106RZ4	Peptidase U32
CU052_09620	ENOG4105CFP	Peptidase U32
CU052_09625	ENOG4105BZU	Histidine kinase
CU052_09630	ENOG4105XPQ	lipid carrier protein
CU052_09635	ENOG4108YYD	acetyltransferase
CU052_09655	ENOG4105BZU	Histidine kinase
CU052_09660	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
CU052_09670	ENOG4105EYA	deoxyribonuclease
CU052_09675	ENOG4105D9N	nucleoside
CU052_09680	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CU052_09685	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CU052_09690	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
CU052_09695	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CU052_09705	ENOG4105EAC	phosphoserine phosphatase
CU052_09715	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CU052_09720	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CU052_09725	ENOG4105ETT	transcriptional Regulator, LysR family
CU052_09735	ENOG4108IQE	Amp-dependent synthetase and ligase
CU052_09825	ENOG41064T2	transcriptional regulator, lysR family
CU052_09830	ENOG4105E5D	amino acid
CU052_09835	ENOG4105FK9	beta-D-galactosidase beta subunit
CU052_09840	ENOG4105CNT	hydrolase family 2
CU052_09850	ENOG4108Y51	tRNA-binding protein
CU052_09860	ENOG4105CI1	PTS System
CU052_09870	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
CU052_09875	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
CU052_09880	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
CU052_09885	ENOG4105CMR	udp-glucose 4-epimerase
CU052_09890	ENOG4105CJN	penicillin-binding protein
CU052_09900	ENOG4105CQ4	Transcriptional regulator
CU052_09920	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
CU052_09925	ENOG4105E98	transcriptional regulator DeoR family
CU052_09930	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CU052_09935	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CU052_09945	ENOG4105CXY	transporter
CU052_09950	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
CU052_09955	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
CU052_09970	ENOG4105X2V	dna damage-inducible protein
CU052_09975	ENOG4105EVZ	LysR family transcriptional regulator
CU052_09985	ENOG4105E68	Sulfatase
CU052_09990	ENOG4105DSY	exodeoxyribonuclease V, gamma
CU052_09995	ENOG4107QKA	exodeoxyribonuclease V beta
CU052_10000	ENOG4107QYX	exodeoxyribonuclease v alpha
CU052_10025	ENOG4107QZM	n-acetylglutamate synthase
CU052_10040	ENOG4105CA3	membrane-bound lytic murein transglycosylase
CU052_10045	ENOG4105CUZ	uba thif-type nad fad binding protein
CU052_10050	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
CU052_10055	ENOG4105C9B	Cysteine desulfurase
CU052_10060	ENOG4107S0N	DJ-1 family
CU052_10065	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CU052_10070	ENOG4105DRB	nucleoside-specific channel-forming protein
CU052_10090	ENOG4105K6V	RNA polymerase
CU052_10105	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CU052_10115	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
CU052_10120	ENOG4105M85	Bola protein
CU052_10125	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CU052_10130	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CU052_10135	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CU052_10140	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CU052_10145	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CU052_10150	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
CU052_10155	ENOG4105CJ2	(LipO)protein
CU052_10165	ENOG4105BZU	Histidine kinase
CU052_10170	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CU052_10175	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CU052_10180	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CU052_10195	ENOG4105C8J	)-transporter
CU052_10205	ENOG4105W1I	UPF0253 protein
CU052_10215	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CU052_10220	ENOG4108R96	Methyltransferase, YaeB family
CU052_10225	ENOG4105NRA	50s ribosomal protein l31 type b
CU052_10235	ENOG4105CFC	Transporter
CU052_10260	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
CU052_10270	ENOG4108UPT	UPF0178 protein
CU052_10305	ENOG4105WP7	tRNA pseudouridine synthase C
CU052_10310	ENOG4105DR9	pseudouridine synthase
CU052_10315	ENOG4108T8E	UPF0325 protein
CU052_10320	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
CU052_10325	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CU052_10330	ENOG4105CE9	30S ribosomal protein S2
CU052_10335	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CU052_10340	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CU052_10345	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CU052_10350	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CU052_10355	ENOG4105KNE	Phosphatidate cytidylyltransferase
CU052_10360	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CU052_10365	ENOG4105DZP	Membrane-associated zinc metalloprotease
CU052_10375	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
CU052_10380	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CU052_10385	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CU052_10390	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CU052_10395	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
CU052_10400	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CU052_10405	ENOG4105C0B	DNA polymerase III (alpha subunit)
CU052_10410	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
CU052_10415	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CU052_10420	ENOG4105N7H	Cytochrome
CU052_10425	ENOG4108YZA	Nitrogen regulatory protein pii
CU052_10430	ENOG4107NA1	Endonuclease Exonuclease phosphatase
CU052_10440	ENOG4105E9H	Lytic Murein transglycosylase
CU052_10445	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
CU052_10450	ENOG4105D1A	Methyltransferase
CU052_10455	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CU052_10460	ENOG4107RZZ	dna polymerase iii epsilon subunit
CU052_10480	ENOG4107QPN	acyl-Coa dehydrogenase
CU052_10485	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
CU052_10490	ENOG4105E7A	Glutamine amidotransferase
CU052_10495	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CU052_10505	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CU052_10510	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
CU052_10515	ENOG4105C2W	permease
CU052_10530	ENOG4105CS1	NAD(P)H quinone oxidoreductase
CU052_10535	ENOG4105K89	arsenate reductase
CU052_10540	ENOG4105ERG	peptidase m48, ste24p
CU052_10555	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CU052_10560	ENOG4105DZR	Type I site-specific deoxyribonuclease
CU052_10570	ENOG4105EKX	Restriction modification system DNA (Specificity
CU052_10575	ENOG4105CVR	type I restriction-modification system
CU052_10635	ENOG4105IBP	Cyclic peptide transporter
CU052_10640	ENOG4105E43	Extracellular solute-binding protein, family 5
CU052_10645	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
CU052_10650	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
CU052_10655	ENOG4108JQ5	ABC transporter
CU052_10675	ENOG4105E0K	tonB-dependent siderophore receptor
CU052_10680	ENOG4105WQT	MbtH domain protein
CU052_10730	ENOG4107RAN	Peptidase, M16
CU052_10735	ENOG4105CQ0	ABC transporter
CU052_10740	ENOG4105PE1	Receptor
CU052_10760	ENOG4109015	Biopolymer transport protein exbD tolR
CU052_10820	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CU052_10860	ENOG4105RH4	Glycine cleavage system transcriptional repressor
CU052_10870	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
CU052_10885	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CU052_10890	ENOG4105KUZ	arsenate reductase
CU052_10910	ENOG4105QZU	Inner membrane protein YfeZ
CU052_10915	ENOG4105EZR	dyp-type peroxidase family protein
CU052_10920	ENOG4108K2B	transcriptional regulator
CU052_10925	ENOG4105F8D	glycoside hydrolase family 4
CU052_10930	ENOG4105CT4	transporter
CU052_10935	ENOG4105I03	Flagellin
CU052_10945	ENOG4105I03	Flagellin
CU052_10955	ENOG4105I03	Flagellin
CU052_10960	ENOG41063QE	flagellar protein FlaG
CU052_10965	ENOG4107BRV	flagellar capping protein
CU052_10975	ENOG4105MQ3	flagellar protein FliS
CU052_10985	ENOG4105BZU	Histidine kinase
CU052_10990	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CU052_10995	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CU052_11000	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CU052_11005	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CU052_11015	ENOG4108JIR	Flagellum-specific ATP synthase
CU052_11040	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CU052_11045	ENOG4105DD5	Flagellar motor switch protein
CU052_11050	ENOG4105VTB	flagellar biosynthesis protein fliO
CU052_11055	ENOG4105CN7	Flagellar biosynthetic protein FliP
CU052_11060	ENOG4105VS8	Flagellar biosynthetic protein fliq
CU052_11065	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CU052_11070	ENOG4105D00	flagellar biosynthetic protein flhB
CU052_11075	ENOG4105D7B	Flagellar biosynthesis protein flha
CU052_11080	ENOG4105FZW	flagellar biosynthesis regulator FlhF
CU052_11085	ENOG4107R21	site-determining protein
CU052_11090	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CU052_11095	ENOG4108VYJ	response regulator receiver protein
CU052_11100	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
CU052_11105	ENOG4105CBS	Chea signal transduction histidine kinase
CU052_11110	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CU052_11115	ENOG4107QJE	Chromosome Partitioning Protein
CU052_11125	ENOG4108V3W	Chemotaxis protein, CheW
CU052_11135	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
CU052_11140	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
CU052_11145	ENOG41060IM	Heme exporter protein
CU052_11155	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
CU052_11160	ENOG4105DA4	cytochrome c-type biogenesis protein
CU052_11165	ENOG4107QX9	Thiol disulfide interChange protein
CU052_11170	ENOG4108M1T	Cytochrome c-type biogenesis protein
CU052_11175	ENOG4105KWW	Biogenesis protein
CU052_11180	ENOG410903C	(LipO)protein
CU052_11185	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CU052_11205	ENOG4105CHU	acetyl-coa acetyltransferase
CU052_11210	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
CU052_11215	ENOG4107QXK	peptidase
CU052_11220	ENOG4108BY2	phosphohistidine phosphatase
CU052_11225	ENOG4108DG9	Smr protein MutS2
CU052_11230	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
CU052_11235	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CU052_11240	ENOG4105EN6	Membrane
CU052_11245	ENOG4108BPE	-transporting atpase
CU052_11250	ENOG4105MH2	YfcL protein
CU052_11260	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
CU052_11265	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CU052_11275	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
CU052_11280	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CU052_11290	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CU052_11300	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CU052_11305	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
CU052_11310	ENOG4108S3P	Sporulation domain protein
CU052_11315	ENOG4105E96	Colicin v production protein
CU052_11320	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
CU052_11325	ENOG4105EJC	lysr family transcriptional regulator
CU052_11330	ENOG4105I93	response regulator
CU052_11340	ENOG4105WD1	Membrane
CU052_11345	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CU052_11350	ENOG4107QMP	dna polymerase iii subunits gamma and tau
CU052_11355	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CU052_11360	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CU052_11365	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
CU052_11370	ENOG4105C44	Serine transporter
CU052_11380	ENOG4105CEM	UPF0597 protein
CU052_11385	ENOG4105WWK	YheO domain protein
CU052_11390	ENOG4105KRS	Proteinase inhibitor
CU052_11395	ENOG4108ZZ3	UPF0260 protein
CU052_11490	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
CU052_11500	ENOG4105Y3U	Transglycosylase-associated protein
CU052_11510	ENOG41067V3	Antibiotic biosynthesis monooxygenase
CU052_11515	ENOG4108UYE	Lactoylglutathione lyase
CU052_11525	ENOG4105G6Z	alkaline phosphatase
CU052_11545	ENOG4105DHI	Methyltransferase
CU052_11550	ENOG4107SDU	Methyl-accepting chemotaxis
CU052_11560	ENOG4105DSB	aldose 1-epimerase
CU052_11565	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
CU052_11570	ENOG4105E0X	reductase
CU052_11580	ENOG4105VUT	cytoplasmic protein
CU052_11585	ENOG4105HDK	L-asparaginase
CU052_11590	ENOG4105D07	Signal peptide peptidase, SppA
CU052_11595	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CU052_11600	ENOG41069NU	Nitroreductase
CU052_11605	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CU052_11615	ENOG4108RU0	short-chain dehydrogenase reductase
CU052_11620	ENOG4105DGU	Histone deacetylase
CU052_11630	ENOG4105E68	Sulfatase
CU052_11635	ENOG4105YDX	UPF0352 protein
CU052_11640	ENOG4106V8H	Nucleoid-associated protein
CU052_11655	ENOG4105DFD	Na H antiporter
CU052_11660	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CU052_11665	ENOG4105EYW	Ion transport protein
CU052_11670	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CU052_11675	ENOG4108EKI	Dehydrogenase
CU052_11690	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CU052_11695	ENOG4105M2J	Glutaredoxin
CU052_11705	ENOG4105D3Y	Na H antiporter
CU052_11710	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
CU052_11715	ENOG4105EIY	sodium-type flagellar protein motY
CU052_11720	ENOG4106WH9	Protein of unknown function (DUF2753)
CU052_11725	ENOG4108UYE	Lactoylglutathione lyase
CU052_11730	ENOG4105CSM	endonuclease III
CU052_11735	ENOG4105DZB	Electron transport complex
CU052_11740	ENOG4108UQQ	Electron transport complex
CU052_11745	ENOG4105D6A	Electron transport complex
CU052_11755	ENOG4108R3D	Electron transport complex
CU052_11760	ENOG4105DGN	Electron transport complex
CU052_11765	ENOG4105C6N	Formate acetyltransferase
CU052_11775	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
CU052_11780	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CU052_11790	ENOG4105CHW	UPF0052 protein
CU052_11795	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CU052_11800	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CU052_11805	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CU052_11810	ENOG4105M00	molybdopterin converting factor, subunit 1
CU052_11815	ENOG4108ZAF	Molybdopterin
CU052_11835	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CU052_11840	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU052_11845	ENOG4105C3U	ABC transporter
CU052_11850	ENOG4108JQ7	(ABC) transporter
CU052_11855	ENOG4105CHF	Glutathione S-transferase
CU052_11860	ENOG4107PU6	Membrane
CU052_11865	ENOG4108DNC	Involved in acetate metabolism (By similarity)
CU052_11870	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CU052_11875	ENOG4105PQ6	UPF0208 membrane protein
CU052_11890	ENOG4105C7J	ABC transporter, permease
CU052_11895	ENOG4108JJB	ABC transporter
CU052_11915	ENOG4105BZU	Histidine kinase
CU052_11920	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
CU052_11925	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CU052_11930	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CU052_11935	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CU052_11940	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
CU052_11950	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CU052_11955	ENOG4105D1F	ATP-binding protein
CU052_11960	ENOG4105DBI	uridine monophosphokinase
CU052_11970	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
CU052_11980	ENOG4105CHH	sulfate transporter
CU052_11990	ENOG4105C03	ribonuclease
CU052_11995	ENOG4105EI2	Pseudouridine synthase
CU052_12000	ENOG4108UHJ	MAF-like protein
CU052_12005	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
CU052_12010	ENOG4105VGS	50s ribosomal protein l32
CU052_12015	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CU052_12020	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CU052_12025	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CU052_12030	ENOG4105CHR	reductase
CU052_12035	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CU052_12040	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
CU052_12050	ENOG4105HHA	aminodeoxychorismate lyase
CU052_12055	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CU052_12060	ENOG4107QRG	dna polymerase iii
CU052_12065	ENOG4105F8V	Hydrolase, tatD family
CU052_12070	ENOG4105CI1	PTS System
CU052_12085	ENOG4105C8J	)-transporter
CU052_12100	ENOG4108NRW	Phospholipase, patatin family
CU052_12105	ENOG4105CA9	Pyruvate kinase
CU052_12110	ENOG4105DAG	ROK family
CU052_12115	ENOG4107R88	Chemotaxis protein (CheV)
CU052_12120	ENOG4105C0B	DNA polymerase III (alpha subunit)
CU052_12145	ENOG4105BZS	acriflavin resistance protein
CU052_12155	ENOG4105UBK	short-chain dehydrogenase reductase
CU052_12160	ENOG4105ERU	peptidase
CU052_12165	ENOG4105CAT	Cytidine monophosphate kinase
CU052_12170	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CU052_12175	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CU052_12180	ENOG4105Q4A	inner membrane protein yciS
CU052_12185	ENOG4105CFV	Tetratricopeptide repeat protein
CU052_12190	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CU052_12195	ENOG4108J59	Extracellular solute-binding protein, family 5
CU052_12250	ENOG4108Q2G	(LipO)protein
CU052_12255	ENOG4105DY2	Paraquat-inducible protein b
CU052_12260	ENOG4105F1S	paraquat-inducible protein a
CU052_12265	ENOG4105JQN	Transcriptional regulator
CU052_12275	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
CU052_12280	ENOG4105N6Y	Thioredoxin
CU052_12310	ENOG41080VW	acetyltransferase
CU052_12335	ENOG4107RBB	ABC transporter, permease
CU052_12345	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CU052_12375	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
CU052_12390	ENOG41090MY	MarR family Transcriptional regulator
CU052_12400	ENOG4105J12	Multidrug resistance protein mdtN
CU052_12405	ENOG4105EQ2	LysR family Transcriptional regulator
CU052_12425	ENOG41062D9	Histidine kinase
CU052_12430	ENOG4105ETX	regulatoR
CU052_12440	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
CU052_12465	ENOG4105WWK	YheO domain protein
CU052_12470	ENOG4105KME	endoribonuclease L-psp
CU052_12475	ENOG4107R6U	sodium dicarboxylate symporter
CU052_12480	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
CU052_12520	ENOG4105CCT	upf0313 protein
CU052_12540	ENOG4105DZ2	Transcriptional regulator
CU052_12555	ENOG4105K9H	YciI-like protein
CU052_12560	ENOG4105NAU	thioesterase Superfamily protein
CU052_12565	ENOG4107835	probably involved in intracellular septation (By similarity)
CU052_12575	ENOG4105BZU	Histidine kinase
CU052_12585	ENOG4105CK2	sodium dicarboxylate symporter
CU052_12590	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CU052_12595	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CU052_12600	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CU052_12605	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CU052_12610	ENOG4105DDQ	anthranilate synthase
CU052_12615	ENOG4105CRQ	synthase (Component I)
CU052_12625	ENOG4105DB7	PHP domain protein
CU052_12630	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
CU052_12640	ENOG4105FE9	pseudouridine synthase
CU052_12645	ENOG4108W5H	UPF0263 protein
CU052_12660	ENOG4105CQ2	DNA polymerase
CU052_12665	ENOG4105WH1	Two component transcriptional regulator luxr family
CU052_12670	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CU052_12715	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
CU052_12740	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CU052_12745	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CU052_12755	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CU052_12760	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CU052_12775	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
CU052_12785	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
CU052_12790	ENOG4105DVI	reductase, NrfD
CU052_12795	ENOG4105DA4	cytochrome c-type biogenesis protein
CU052_12800	ENOG4107QX9	Thiol disulfide interChange protein
CU052_12805	ENOG4108DMF	Cytochrome C biogenesis protein
CU052_12815	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
CU052_12840	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
CU052_12845	ENOG4105EAQ	(twin-arginine translocation) pathway signal
CU052_12850	ENOG4105C5X	domain protein
CU052_12865	ENOG4105CH5	extracellular solute-binding protein, family 7
CU052_12875	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CU052_12890	ENOG41067TZ	transcriptional regulator, MarR family
CU052_12895	ENOG4105C94	Transporter
CU052_12900	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_12920	ENOG4105CGF	Aromatic amino acid aminotransferase
CU052_12925	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CU052_12960	ENOG4105C5S	asparaginyl-tRNA synthetase
CU052_12965	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_12970	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
CU052_12975	ENOG4105WH1	Two component transcriptional regulator luxr family
CU052_12985	ENOG4105BZU	Histidine kinase
CU052_12990	ENOG4105EJQ	L-serine dehydratase
CU052_12995	ENOG4105C44	Serine transporter
CU052_13015	ENOG4105CRQ	synthase (Component I)
CU052_13030	ENOG4105CM6	amino acid regulated cytosolic protein
CU052_13035	ENOG4106K28	UPF0283 membrane protein
CU052_13045	ENOG4105D9U	N-acetyltransferase
CU052_13185	ENOG4105C8V	SAICAR synthetase
CU052_13205	ENOG4105CDV	Ompa motb domain protein
CU052_13220	ENOG4105CQB	FAD linked oxidase domain protein
CU052_13235	ENOG4105C84	Histidine ammonia-lyase
CU052_13240	ENOG4105CGP	Urocanate hydratase
CU052_13245	ENOG41088SP	formiminoglutamate hydrolase
CU052_13250	ENOG4105CI2	imidazolone-5-propionate hydrolase
CU052_13255	ENOG4105CZE	histidine utilization repressor
CU052_13270	ENOG4105C22	threonyL-tRNA synthetase
CU052_13275	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CU052_13280	ENOG41082NX	50s ribosomal protein l35
CU052_13285	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CU052_13290	ENOG4105KME	endoribonuclease L-psp
CU052_13295	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
CU052_13300	ENOG4105K8R	UPF0145 protein
CU052_13365	ENOG4108XTP	Transcriptional regulator
CU052_13445	ENOG4108N0N	Phage Terminase Large Subunit
CU052_13450	ENOG4107ZQ5	Phage-associated protein, HI1409 family
CU052_13600	ENOG4105BZU	Histidine kinase
CU052_13605	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CU052_13610	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CU052_13650	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
CU052_13660	ENOG4105FQ6	thiopurine methyltransferase
CU052_13665	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
CU052_13670	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
CU052_13675	ENOG41067MG	lrgb family
CU052_13680	ENOG4105VAW	lrga family
CU052_13685	ENOG4105CJB	Exodeoxyribonuclease I
CU052_13690	ENOG41082W1	Cupin 2, conserved barrel domain protein
CU052_13695	ENOG4105N14	lysine exporter protein LysE YggA
CU052_13700	ENOG4105CG9	aspartate racemase
CU052_13720	ENOG4108ETY	sodium dicarboxylate symporter
CU052_13725	ENOG4105K4T	epimerase
CU052_13730	ENOG4107XWI	flavin reductase domain protein, FMN-binding
CU052_13735	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
CU052_13740	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
CU052_13750	ENOG410902C	phosphohistidine phosphatase, SixA
CU052_13760	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
CU052_13765	ENOG4108IU2	vtamin B12-transporter permease
CU052_13770	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
CU052_13825	ENOG4105F04	LysR family Transcriptional regulator
CU052_13850	ENOG4108VAU	general secretion pathway protein G
CU052_13855	ENOG4108VKG	metal-dependent hydrolase
CU052_13860	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
CU052_13865	ENOG4105BZU	Histidine kinase
CU052_13885	ENOG4105CTU	Proline racemase
CU052_13890	ENOG41080HI	glycine oxidase
CU052_13900	ENOG4105CIF	Ornithine Cyclodeaminase
CU052_13905	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CU052_13910	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CU052_13915	ENOG4105F38	ABC transporter, permease
CU052_13920	ENOG4105D38	putrescine abc transporter
CU052_13925	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
CU052_13945	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
CU052_13950	ENOG4105BZS	acriflavin resistance protein
CU052_13960	ENOG4105ETX	regulatoR
CU052_13995	ENOG4108JQ7	(ABC) transporter
CU052_14000	ENOG4105C3U	ABC transporter
CU052_14005	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
CU052_14010	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
CU052_14015	ENOG4107QSI	ABC, transporter
CU052_14020	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CU052_14030	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
CU052_14035	ENOG4105F1J	Homogentisate 1,2-dioxygenase
CU052_14045	ENOG4108RXX	maleylacetoacetate isomerase
CU052_14100	ENOG4108Z4K	mutator MutT protein
CU052_14115	ENOG4107QSI	ABC, transporter
CU052_14140	ENOG4106YYS	transcriptional regulatory protein
CU052_14145	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CU052_14150	ENOG4105D9Q	decarboxylase (Beta subunit)
CU052_14155	ENOG4107QSA	Oxaloacetate decarboxylase
CU052_14170	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
CU052_14175	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
CU052_14180	ENOG4105CI0	Citrate lyase
CU052_14185	ENOG4105CHY	citrate lyase, alpha
CU052_14190	ENOG4105YGP	holo-ACP synthase CitX
CU052_14195	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
CU052_14225	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
CU052_14230	ENOG4105C26	Dehydrogenase
CU052_14235	ENOG4105BZG	amino acid carrier protein
CU052_14270	ENOG4105E0M	Sulfatase
CU052_14280	ENOG410607W	Transposase
CU052_14295	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CU052_14300	ENOG4105HEI	LysR family (Transcriptional regulator
CU052_14320	ENOG4107YCY	Transcriptional regulator
CU052_14360	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
CU052_14365	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
CU052_14380	ENOG4107ZT5	Thiol disulfide interchange protein
CU052_14400	ENOG4105CUW	cytochrome C-TYPE protein
CU052_14420	ENOG4108KAM	Transcriptional regulator
CU052_14435	ENOG4105C4R	Atp-dependent dna helicase
CU052_14450	ENOG4107V40	secretion protein, HlyD family
CU052_14465	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
CU052_14470	ENOG4108V9W	transcriptional regulatory protein
CU052_14475	ENOG4105E0K	tonB-dependent siderophore receptor
CU052_14480	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
CU052_14485	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
CU052_14490	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
CU052_14495	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
CU052_14530	ENOG4107VGF	ig domain protein group 2 domain protein
CU052_14535	ENOG4105ER2	Ompa motb domain protein
CU052_14565	ENOG4105KXC	Collagenase
CU052_14575	ENOG4106R3P	AraC family transcriptional regulator
CU052_14650	ENOG4105CDV	Ompa motb domain protein
CU052_14665	ENOG4105DR4	Methyltransferase
CU052_14670	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_14675	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
CU052_14680	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
CU052_14685	ENOG4108MN8	Membrane
CU052_14690	ENOG4105CDA	abc transporter atp-binding protein
CU052_14695	ENOG4105DRP	amino acid AbC transporter
CU052_14700	ENOG4105EZ7	amino acid ABC transporter
CU052_14705	ENOG4107QXX	ABC transporter
CU052_14720	ENOG4108VPT	UPF0234 protein
CU052_14725	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CU052_14750	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CU052_14755	ENOG4105DY2	Paraquat-inducible protein b
CU052_14760	ENOG4105H2K	paraquat-inducible protein a
CU052_14765	ENOG4105BZ1	(ABC) transporter
CU052_14770	ENOG4108ZGC	gaf domain protein
CU052_14775	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
CU052_14780	ENOG4105CN1	protease
CU052_14790	ENOG4105CD8	aminopeptidase N
CU052_14800	ENOG4105C7I	Dehydrogenase
CU052_14810	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
CU052_14815	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
CU052_14820	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CU052_14830	ENOG4105C5H	ABC transporter
CU052_14845	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
CU052_14850	ENOG4105DAN	ATP-dependent protease
CU052_14855	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
CU052_14885	ENOG4105BZU	Histidine kinase
CU052_14900	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
CU052_14915	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
CU052_14925	ENOG4105C59	p-type ATPase
CU052_14940	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CU052_14945	ENOG4105Q9Y	Universal stress protein
CU052_14950	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CU052_14960	ENOG4108UR8	BAX protein
CU052_14970	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CU052_14975	ENOG4105F38	ABC transporter, permease
CU052_14980	ENOG4105D38	putrescine abc transporter
CU052_14985	ENOG4107RUE	extracellular solute-binding protein family 1
CU052_14990	ENOG4107RUE	extracellular solute-binding protein family 1
CU052_14995	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CU052_15015	ENOG4105QAX	Iron-sulfur
CU052_15020	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CU052_15030	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
CU052_15050	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
CU052_15055	ENOG4105C5H	ABC transporter
CU052_15075	ENOG4105BZU	Histidine kinase
CU052_15090	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CU052_15095	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
CU052_15100	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CU052_15110	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
CU052_15115	ENOG4106IUH	DTW domain containing protein
CU052_15165	ENOG4108N3W	hemolysin secretion protein
CU052_15170	ENOG4107TT5	NLP P60 protein
CU052_15180	ENOG4105BZU	Histidine kinase
CU052_15185	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CU052_15190	ENOG4105FGM	Fructosamine kinase
CU052_15200	ENOG4108R6K	riboflavin synthase, subunit alpha
CU052_15205	ENOG4107QI1	Mate efflux family protein
CU052_15220	ENOG41082AN	stage II sporulation protein
CU052_15230	ENOG4107V1M	polysaccharide export protein
CU052_15245	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CU052_15285	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
CU052_15305	ENOG4105F88	accessory colonization factor AcfD
CU052_15325	ENOG4105CDV	Ompa motb domain protein
CU052_15335	ENOG410620I	Diguanylate cyclase
CU052_15340	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
CU052_15345	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
CU052_15350	ENOG410667J	hydrolase
CU052_15360	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
CU052_15370	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CU052_15375	ENOG4105C7F	AcnD-accessory protein PrpF
CU052_15380	ENOG4108I0Z	Aconitate hydratase
CU052_15385	ENOG4105BZN	citrate synthase
CU052_15390	ENOG4105CR4	methylisocitrate lyase
CU052_15405	ENOG4105CS6	Rhs element vgr protein
CU052_15460	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CU052_15500	ENOG4108ESY	Metal dependent phosphohydrolase
CU052_15510	ENOG4105KD7	acetyltransferase
CU052_15535	ENOG4105EJ9	Membrane
CU052_15570	ENOG410829K	Lysine exporter protein (Lyse ygga)
CU052_15605	ENOG4105WH1	Two component transcriptional regulator luxr family
CU052_15610	ENOG4105CTD	carboxy-peptidase
CU052_15620	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
CU052_15635	ENOG4105D1S	lipid A biosynthesis
CU052_15640	ENOG4105HEI	LysR family (Transcriptional regulator
CU052_15645	ENOG4105N14	lysine exporter protein LysE YggA
CU052_15650	ENOG4105E5D	amino acid
CU052_15670	ENOG4105CVG	Homoserine O-transsuccinylase
CU052_15675	ENOG41090FY	type IV pilus biogenesis stability protein PilW
CU052_15700	ENOG4105CQ7	ATP-dependent helicase
CU052_15705	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CU052_15715	ENOG4108NEM	leader-binding protein dmsD
CU052_15720	ENOG4107KGK	dmso reductase anchor subunit
CU052_15725	ENOG4105QAX	Iron-sulfur
CU052_15730	ENOG4107QY8	reductase
CU052_15760	ENOG4105BZU	Histidine kinase
CU052_15770	ENOG4105CFG	Acts as a chaperone (By similarity)
CU052_15775	ENOG4105CFG	Acts as a chaperone (By similarity)
CU052_15800	ENOG4105CR8	Transcriptional regulator
CU052_15815	ENOG4105BZ1	(ABC) transporter
CU052_15820	ENOG4105BZ1	(ABC) transporter
CU052_15835	ENOG4105E0K	tonB-dependent siderophore receptor
CU052_15840	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
CU052_15845	ENOG4105J76	Periplasmic binding protein
CU052_15850	ENOG4105E0A	ABC, transporter
CU052_15865	ENOG4105E0U	tyrosine-specific transport protein
CU052_15870	ENOG4105C0A	alcohol dehydrogenase
CU052_15880	ENOG4105BZU	Histidine kinase
CU052_15890	ENOG4105DHT	Metal Dependent Phosphohydrolase
CU052_15900	ENOG4105EE5	Membrane protein terC
CU052_15910	ENOG41076CZ	activating enzyme
CU052_15915	ENOG4105G0K	glycine radical enzyme YjjI family
CU052_15925	ENOG4105CPI	Metal Dependent Phosphohydrolase
CU052_15930	ENOG4105BZU	Histidine kinase
CU052_15935	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CU052_15940	ENOG4105BZU	Histidine kinase
CU052_15945	ENOG4105C8P	)-transporter
CU052_15990	ENOG4105CQ7	ATP-dependent helicase
CU052_15995	ENOG4107R1I	NAD-dependent malic enzyme
CU052_16000	ENOG4107GZ4	SanA protein
CU052_16005	ENOG4105C8P	)-transporter
CU052_16010	ENOG4105BZU	Histidine kinase
CU052_16030	ENOG4105C3M	thioredoxin reductase
CU052_16035	ENOG4108JJ9	ABC, transporter
CU052_16040	ENOG4108JJ8	(ABC) transporter
CU052_16045	ENOG4105BZC	d-serine deaminase
CU052_16055	ENOG4105W8I	Transcriptional regulator
CU052_16075	ENOG4105BZU	Histidine kinase
CU052_16085	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CU052_16095	ENOG4105BZU	Histidine kinase
CU052_16125	ENOG4105DWU	Membrane
CU052_16135	ENOG4105DY8	decarboxylase
CU052_16140	ENOG4106KNT	transcriptional regulator
CU052_16150	ENOG41090BQ	Glutaredoxin
CU052_16155	ENOG4105D0C	transport protein
CU052_16160	ENOG4105RKW	reductase (By
CU052_16165	ENOG4107QPN	acyl-Coa dehydrogenase
CU052_16170	ENOG41067SE	Tetr family transcriptional regulator
CU052_16175	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
CU052_16190	ENOG4108I0Y	(ABC) transporter
CU052_16195	ENOG4107QI1	Mate efflux family protein
CU052_16200	ENOG4105CGD	Nad-dependent epimerase dehydratase
CU052_16205	ENOG4105ETE	Transcriptional regulator (LacI family
CU052_16215	ENOG4107RUZ	Sss sodium solute transporter superfamily
CU052_16225	ENOG4105C2C	drug resistance transporter, Bcr CflA
CU052_16230	ENOG4105I08	Pseudouridine synthase
CU052_16235	ENOG4105CFI	type iii restriction protein res subunit
CU052_16245	ENOG4105ETX	regulatoR
CU052_16250	ENOG4105E0F	Histidine kinase
CU052_16270	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
CU052_16285	ENOG4105CGH	5'-nucleotidase
CU052_16295	ENOG4105XZD	Fe-S protein
CU052_16305	ENOG4105CHH	sulfate transporter
CU052_16315	ENOG4108ZXC	Two component transcriptional regulator, luxr family
CU052_16320	ENOG4106AFQ	Histidine kinase
CU052_16340	ENOG4108RSN	SNARE associated Golgi
CU052_16345	ENOG4105VNH	ABC transporter solute-binding protein
CU052_16350	ENOG4105CXZ	ABC transporter, permease
CU052_16355	ENOG4108VGW	abc transporter atp-binding protein
CU052_16360	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
CU052_16365	ENOG4108JUA	Transcriptional regulator
CU052_16370	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CU052_16375	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
CU052_16385	ENOG4108W1A	pseudouridine synthase
CU052_16395	ENOG4105C8J	)-transporter
CU052_16405	ENOG4105C28	cystathionine
CU052_16410	ENOG4107IFA	Lipase (EC 3.1.1.3)
CU052_16420	ENOG4108R3E	Dna-3-methyladenine glycosylase i
CU052_16430	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CU052_16445	ENOG4105YYT	phage shock protein B
CU052_16450	ENOG41087YS	Phage shock protein A
CU052_16455	ENOG4105E51	psp operon transcriptional activator
CU052_16460	ENOG4108J59	Extracellular solute-binding protein, family 5
CU052_16465	ENOG4108I5W	peptide transport system, permease protein
CU052_16470	ENOG4108EU3	peptide transport system, permease
CU052_16475	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
CU052_16480	ENOG4108JQ2	peptide transport system atp-binding protein
CU052_16490	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
CU052_16495	ENOG4105CC5	ABC transporter
CU052_16500	ENOG4105CC5	ABC transporter
CU052_16505	ENOG4105DIK	(ABC) transporter
CU052_16520	ENOG4108J2R	molybdopterin oxidoreductase
CU052_16540	ENOG4105TMB	Formate nitrite transporter
CU052_16570	ENOG4107104	thymidine kinase
CU052_16575	ENOG4105C8N	cysteinyl-tRNA synthetase
CU052_16580	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CU052_16585	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
CU052_16590	ENOG4105D58	Diguanylate phosphodiesterase
CU052_16595	ENOG4105K5B	UPF0225 protein
CU052_16620	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CU052_16625	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CU052_16635	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CU052_16640	ENOG4107S6Z	Na H antiporter
CU052_16645	ENOG4108YX2	DNA-binding protein
CU052_16650	ENOG4107RE1	Inosine-guanosine kinase
CU052_16660	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CU052_16665	ENOG41075W9	High frequency lysogenization protein HflD homolog
CU052_16670	ENOG4107QTF	adenylosuccinate lyase
CU052_16680	ENOG4105RHG	
CU052_16690	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CU052_16705	ENOG4107FW0	short-chain dehydrogenase reductase
CU052_16715	ENOG4105D0M	Protease HtpX homolog
CU052_16725	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CU052_16735	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CU052_16740	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CU052_16745	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
CU052_16750	ENOG4105KSC	Transcriptional regulator, TraR DksA family
CU052_16765	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CU052_16770	ENOG4105D1H	recombination factor protein RarA
CU052_16775	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
CU052_16780	ENOG4105CNU	cell division protein FtsK
CU052_16785	ENOG4105EW9	transcriptional regulator AsnC family
CU052_16790	ENOG4105DCF	alanine dehydrogenase
CU052_16800	ENOG4107R11	Transcriptional regulator
CU052_16950	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
CU052_16980	ENOG4105KXC	Collagenase
CU052_16990	ENOG4105PBD	transposase, IS3 IS911 family protein
CU052_17180	ENOG41066XE	Type III export protein
CU052_17210	ENOG4108KB1	transcriptional regulator, arac family
CU052_17245	ENOG4105CVR	type I restriction-modification system
CU052_17265	ENOG4105DZR	Type I site-specific deoxyribonuclease
CU052_17285	ENOG4105CVR	type I restriction-modification system
CU052_17335	ENOG4108YGG	dna repair protein
CU052_17380	ENOG4105DFP	Integrase
CU052_17390	ENOG4108RNS	Exports L-alanine (By similarity)
CU052_17395	ENOG4105BZU	Histidine kinase
CU052_17405	ENOG4106032	Glutathionylspermidine synthase
CU052_17415	ENOG4105Z6B	inner membrane protein yjfl
CU052_17425	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CU052_17430	ENOG4105EIP	mannose-6-phosphate isomerase
CU052_17435	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
CU052_17440	ENOG4105DCT	glycerol dehydrogenase
CU052_17445	ENOG4106R3P	AraC family transcriptional regulator
CU052_17450	ENOG4108XCZ	PTS System
CU052_17455	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CU052_17460	ENOG4105EXW	epimerase dehydratase
CU052_17465	ENOG4108AHH	pyruvate formate lyase II activase
CU052_17470	ENOG4105C6N	Formate acetyltransferase
CU052_17475	ENOG4108YRF	PTS System
CU052_17485	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
CU052_17490	ENOG4105D9R	oxidoreductase
CU052_17495	ENOG41090KN	UPF0303 protein
CU052_17500	ENOG4105C2X	Arabinose 5-phosphate isomerase
CU052_17505	ENOG4105UFD	tol-pal system protein YbgF
CU052_17510	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CU052_17515	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
CU052_17525	ENOG4105M8F	Biopolymer transport protein exbD tolR
CU052_17530	ENOG4105E02	MotA TolQ exbB proton channel
CU052_17535	ENOG4107YD3	Thioesterase
CU052_17550	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
CU052_17555	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CU052_17560	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CU052_17565	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CU052_17570	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_17575	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
CU052_17580	ENOG4105C9M	aspartyl-trna synthetase
CU052_17585	ENOG41081XQ	Conserved Protein
CU052_17590	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
CU052_17595	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
CU052_17605	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CU052_17615	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CU052_17625	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
CU052_17630	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
CU052_17635	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
CU052_17640	ENOG4106371	Methyltransferase
CU052_17645	ENOG4107S90	membrAne
CU052_17650	ENOG4106WF9	DNA-binding transcriptional regulator TorR
CU052_17655	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
CU052_17660	ENOG4105ETE	Transcriptional regulator (LacI family
CU052_17665	ENOG4105HP8	regulator of competence-specific genes
CU052_17685	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CU052_17690	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CU052_17695	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CU052_17700	ENOG4105RKX	Protein of unknown function (DUF2498)
CU052_17705	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CU052_17715	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
CU052_17720	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
CU052_17725	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CU052_17730	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CU052_17735	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
CU052_17740	ENOG4105VEQ	Cold shock protein
CU052_17750	ENOG4108R99	pseudouridine synthase
CU052_17765	ENOG4105DVT	helicase
CU052_17770	ENOG4105EJ9	Membrane
CU052_17780	ENOG4106428	Protein of unknown function (DUF2496)
CU052_17785	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_17790	ENOG4105CGK	Exodeoxyribonuclease III
CU052_17800	ENOG4105DSP	amino acid AbC transporter
CU052_17805	ENOG4105E89	ABC transporter
CU052_17810	ENOG4108JEH	abc transporter atp-binding protein
CU052_17830	ENOG4105C6N	Formate acetyltransferase
CU052_17840	ENOG4105F1A	Pyruvate formate-lyase
CU052_17850	ENOG4105XWI	UPF0304 protein
CU052_17860	ENOG4105CYN	Serine protein kinase
CU052_17865	ENOG4106AKX	UPF0229 protein
CU052_17875	ENOG4105CWX	Alpha-1,2-mannosidase
CU052_17885	ENOG4105CWX	Alpha-1,2-mannosidase
CU052_17890	ENOG4105CWX	Alpha-1,2-mannosidase
CU052_17895	ENOG4105DM4	PTS System
CU052_17905	ENOG4105DW5	Transcriptional regulator
CU052_17910	ENOG4108KP7	hydrolase
CU052_17920	ENOG4108JB8	alcohol dehydrogenase
CU052_17925	ENOG4107YBY	Hydrolase
CU052_17930	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CU052_17940	ENOG4105E66	phosphoriboisomerase A
CU052_17945	ENOG4107QSE	Dipeptidase
CU052_17950	ENOG4105CI1	PTS System
CU052_17960	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CU052_17965	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
CU052_17970	ENOG4105N2W	Transcriptional regulator
CU052_17975	ENOG4107P2S	Transcriptional regulator
CU052_17980	ENOG4105CI1	PTS System
CU052_17985	ENOG4105C87	Aminotransferase class I and II
CU052_17990	ENOG4105EIP	mannose-6-phosphate isomerase
CU052_18010	ENOG4105CH6	catalase
CU052_18020	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CU052_18025	ENOG4108RWI	nicotinamidase
CU052_18035	ENOG4107RH7	Nicotinate phosphoribosyltransferase
CU052_18050	ENOG4105RA2	Membrane
CU052_18090	ENOG4108M6U	Universal stress protein A
CU052_18095	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CU052_18110	ENOG4108IJ7	Glycine betaine
CU052_18115	ENOG4108HQS	Glycine betaine
CU052_18125	ENOG4105VYW	UPF0251 protein
CU052_18145	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CU052_18155	ENOG4107S8C	mandelate racemase muconate lactonizing
CU052_18170	ENOG4105D64	Mechanosensitive ion channel
CU052_18180	ENOG4105DMF	Dehydrogenase
CU052_18185	ENOG4105DAA	L-lactate
CU052_18190	ENOG4105CC0	LysR family Transcriptional regulator
CU052_18210	ENOG4108JQ5	ABC transporter
CU052_18220	ENOG4105DAN	ATP-dependent protease
CU052_18235	ENOG4105YE1	PilZ domain
CU052_18250	ENOG4108MK9	spermidine N(1)-acetyltransferase
CU052_18255	ENOG4108BGM	Quinol dehydrogenase periplasmic component
CU052_18260	ENOG4105GXZ	Ferredoxin-type protein NapH
CU052_18280	ENOG4108JJB	ABC transporter
CU052_18285	ENOG4108V7D	UPF0397 protein
CU052_18290	ENOG4105EFX	secretion protein, HlyD family
CU052_18295	ENOG4105KK7	inner membrane protein YiaW
CU052_18305	ENOG4106TD9	Diguanylate cyclase
CU052_18320	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CU052_18330	ENOG4107SEY	Conserved Protein
CU052_18335	ENOG4108XDN	Transcriptional regulator
CU052_18340	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CU052_18345	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
CU052_18355	ENOG4105C1J	atp-dependent rna helicase
CU052_18365	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
CU052_18370	ENOG4107S17	Phosphate-binding protein
CU052_18375	ENOG4105C8U	phosphate abc transporter
CU052_18380	ENOG4105E2Z	phosphate ABC transporter (Permease
CU052_18385	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CU052_18420	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CU052_18425	ENOG41069D7	Methyl-accepting chemotaxis
CU052_18435	ENOG41086KC	Transcriptional regulator
CU052_18440	ENOG41086KC	Transcriptional regulator
CU052_18450	ENOG4108JJ6	Type I secretion system ATPase
CU052_18460	ENOG4108UW5	maltose o-acetyltransferase
CU052_18465	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CU052_18490	ENOG4105C8U	phosphate abc transporter
CU052_18495	ENOG4105E2Z	phosphate ABC transporter (Permease
CU052_18500	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CU052_18505	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CU052_18520	ENOG4105EKQ	RNA-directed DNA polymerase
CU052_18540	ENOG4105KCK	Peptidoglycan-associated lipoprotein
CU052_18550	ENOG4105BZU	Histidine kinase
CU052_18555	ENOG4105CK1	PTS System
CU052_18570	ENOG4105CEP	NADH dehydrogenase
CU052_18595	ENOG4108IJF	Heavy metal efflux pump, CzcA
CU052_18615	ENOG4108IEG	Formate dehydrogenase Alpha subunit
CU052_18650	ENOG4108IA2	Sodium pantothenate symporter
CU052_18655	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
CU052_18660	ENOG4108UHU	Aldolase
CU052_18665	ENOG4105E2D	ec 3.2.1.52
CU052_18675	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
CU052_18680	ENOG4107QWP	ABC-2 type transporter
CU052_18685	ENOG4105CJ1	ABC, transporter
CU052_18695	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_18700	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
CU052_18705	ENOG4105EHG	Permease protein
CU052_18715	ENOG4106GFD	transport protein
CU052_18720	ENOG41090AP	transport protein
CU052_18725	ENOG4105WQ5	TonB family
CU052_18730	ENOG4105D4P	Coproporphyrinogen iii oxidase
CU052_18735	ENOG41090JE	Utilization Protein
CU052_18740	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
CU052_18750	ENOG4107R88	Chemotaxis protein (CheV)
CU052_18755	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
CU052_18795	ENOG4105JQN	Transcriptional regulator
CU052_18825	ENOG4105EJC	lysr family transcriptional regulator
CU052_18840	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
CU052_18845	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CU052_18855	ENOG4108V1U	phospholipid-binding protein
CU052_18870	ENOG4105D6J	arsenicaL-resistance protein
CU052_18885	ENOG4105KVH	Transcriptional regulator
CU052_18900	ENOG4105EIP	mannose-6-phosphate isomerase
CU052_18905	ENOG4105C8I	hydrolase, family 38
CU052_18910	ENOG4105DM4	PTS System
CU052_18915	ENOG4105FDP	GntR family transcriptional regulator
CU052_18920	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
CU052_18925	ENOG4105CTS	PTS system mannitol-specific
CU052_18930	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
CU052_18940	ENOG4107Z1W	Fructose transport system kinase
CU052_18965	ENOG4105E0U	tyrosine-specific transport protein
CU052_18975	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_18980	ENOG4105DWD	nucleoside recognition domain protein
CU052_19005	ENOG4105DR5	peptidase
CU052_19015	ENOG4105CR8	Transcriptional regulator
CU052_19020	ENOG4105E5M	Multidrug resistance protein D
CU052_19040	ENOG4108SXK	Transporter Drug Metabolite Exporter family
CU052_19055	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
CU052_19100	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
CU052_19125	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
CU052_19130	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CU052_19135	ENOG4105UYK	outer membrane protein a
CU052_19140	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
CU052_19145	ENOG4105DXI	Major Facilitator superfamily
CU052_19160	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CU052_19180	ENOG4105BZU	Histidine kinase
CU052_19185	ENOG4105KHC	sulfurtransferase
CU052_19205	ENOG4105D06	uba thif-type nad fad binding protein
CU052_19210	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CU052_19220	ENOG4105EUJ	GTP cyclohydrolase i
CU052_19230	ENOG4105C5A	transporter
CU052_19255	ENOG4107RGM	aldo keto reductase
CU052_19260	ENOG4108UNF	response regulator
CU052_19270	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
CU052_19275	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CU052_19285	ENOG4105ENX	hydrolase
CU052_19290	ENOG4105EQ2	LysR family Transcriptional regulator
CU052_19360	ENOG4108ZG0	Ompa motb domain protein
CU052_19410	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
CU052_19420	ENOG4105BZU	Histidine kinase
CU052_19430	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CU052_19435	ENOG4105C26	Dehydrogenase
CU052_19440	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
CU052_19455	ENOG4108HQS	Glycine betaine
CU052_19460	ENOG4108IJ7	Glycine betaine
CU052_19465	ENOG4108RCM	Nitroreductase
CU052_19475	ENOG4107QX8	SPFH domain, Band 7 family protein
CU052_19490	ENOG4105BZU	Histidine kinase
CU052_19500	ENOG4105CA0	peroxidase
CU052_19505	ENOG4105BZU	Histidine kinase
CU052_19545	ENOG4106W5V	Membrane
CU052_19580	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CU052_19590	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
CU052_19595	ENOG4105C2J	ABC transporter
CU052_19600	ENOG4105CNN	ABC, transporter
CU052_19605	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
CU052_19610	ENOG4108RVA	ribokinase
CU052_19615	ENOG4105ETE	Transcriptional regulator (LacI family
CU052_19625	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
CU052_19630	ENOG4108I5U	Uridine phosphorylase
CU052_19650	ENOG4105DHS	permease protein
CU052_19655	ENOG4105CM4	permease protein
CU052_19660	ENOG4108IPW	abc transporter atp-binding protein
CU052_19665	ENOG4108Z6Z	Transcriptional regulator
CU052_19685	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
CU052_19700	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
CU052_19710	ENOG4105CKI	cobalamin synthesis protein
CU052_19715	ENOG4105BZU	Histidine kinase
CU052_19720	ENOG4105C1J	atp-dependent rna helicase
CU052_19740	ENOG4108M8H	domain protein
CU052_19745	ENOG4105DKW	ABC transporter
CU052_19750	ENOG4105DWP	Membrane
CU052_19760	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
CU052_19780	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CU052_19785	ENOG4105D06	uba thif-type nad fad binding protein
CU052_19895	ENOG4107S17	Phosphate-binding protein
CU052_19910	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
CU052_19915	ENOG4105C1J	atp-dependent rna helicase
CU052_19920	ENOG4105BZU	Histidine kinase
CU052_19925	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
CU052_19930	ENOG4105F04	LysR family Transcriptional regulator
CU052_19940	ENOG4105C26	Dehydrogenase
CU052_19980	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_19985	ENOG4105E5Z	arginine transporter ATP-binding subunit
CU052_19990	ENOG4106PMH	Extracellular solute-binding protein family 3
CU052_19995	ENOG4105GBT	ABC transporter
CU052_20000	ENOG4105DMR	ABC, transporter
CU052_20010	ENOG4105DUM	transcriptional regulator, lysR family
CU052_20025	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
CU052_20035	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
CU052_20040	ENOG4105BZJ	Electron transfer flavoprotein
CU052_20045	ENOG4105C10	Electron transfer flavoprotein
CU052_20050	ENOG4107QSN	dihydrolipoamide acetyltransferase
CU052_20055	ENOG4105CPP	Dehydrogenase, E1 component
CU052_20060	ENOG4107RUY	(E1 component), alpha subunit
CU052_20075	ENOG4105R8A	Heat shock protein
CU052_20080	ENOG4106E5D	Protein of unknown function (DUF461)
CU052_20110	ENOG4105ETX	regulatoR
CU052_20125	ENOG4105G6Z	alkaline phosphatase
CU052_20145	ENOG4105BZU	Histidine kinase
CU052_20155	ENOG4105C44	Serine transporter
CU052_20160	ENOG4105BZU	Histidine kinase
CU052_20180	ENOG4107QYG	anthranilate phosphoribosyltransferase
CU052_20205	ENOG4105DG7	nitrate ABC transporter
CU052_20210	ENOG4105D7T	ABC transporter
CU052_20215	ENOG4107QZF	nitrite reductase NADPH large subunit
CU052_20245	ENOG4105F8J	Adenylate Guanylate cyclase
CU052_20265	ENOG4105DR5	peptidase
CU052_20275	ENOG4105DS1	cytochrome b561
CU052_20300	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CU052_20305	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_20320	ENOG4105IPI	Membrane
CU052_20330	ENOG4105BZU	Histidine kinase
CU052_20350	ENOG4107VQW	regulatoR
CU052_20405	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CU052_20410	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
CU052_20420	ENOG4105CBC	glutamate synthase
CU052_20440	ENOG4105EXC	Acyl-transferase
CU052_20450	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CU052_20455	ENOG4108UYE	Lactoylglutathione lyase
CU052_20480	ENOG4105D9P	serine threonine protein kinase
CU052_20500	ENOG4106VK6	Flagellar motor protein
CU052_20515	ENOG4108ZF3	Phosphatase
CU052_20560	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CU052_20570	ENOG4105CS6	Rhs element vgr protein
CU052_20585	ENOG4107TV1	YD repeat protein
CU052_20610	ENOG4107RFY	SbcCD D subunit
CU052_20615	ENOG4105EYH	Exonuclease
CU052_20660	ENOG4105QNF	Outer membrane lipoprotein
CU052_20670	ENOG4105C2C	drug resistance transporter, Bcr CflA
CU052_20680	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CU052_20690	ENOG4105C5W	Aldolase
CU052_20700	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
CU052_20705	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
CU052_20715	ENOG4105CBN	LysR family transcriptional regulator
CU052_20720	ENOG4105CXG	d-lactate dehydrogenase
CU052_20795	ENOG4105BZU	Histidine kinase
CU052_20800	ENOG4107QZF	nitrite reductase NADPH large subunit
CU052_20805	ENOG4105WZK	nitrite reductase NADPH small subunit
CU052_20810	ENOG4105TMB	Formate nitrite transporter
CU052_20815	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
CU052_20830	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
CU052_20855	ENOG4105VXR	cytoplasmic protein
CU052_20870	ENOG4108ISG	Major Facilitator
CU052_20875	ENOG4105K63	Thioredoxin
CU052_20880	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CU052_20905	ENOG4105EFX	secretion protein, HlyD family
CU052_20915	ENOG4105IPI	Membrane
CU052_20925	ENOG4105EIP	mannose-6-phosphate isomerase
CU052_20930	ENOG4105CXY	transporter
CU052_20935	ENOG4105BZU	Histidine kinase
CU052_20940	ENOG4108KX4	response regulator
CU052_20945	ENOG4105CXY	transporter
CU052_21000	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CU052_21005	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CU052_21010	ENOG4107QI1	Mate efflux family protein
CU052_21015	ENOG4105ECQ	AraC Family Transcriptional Regulator
CU052_21020	ENOG4105CGF	Aromatic amino acid aminotransferase
CU052_21025	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CU052_21035	ENOG4105WXI	Bacterial OB fold (BOF) protein
CU052_21040	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
CU052_21045	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
CU052_21050	ENOG4105E0C	molybdate abc transporter
CU052_21055	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
CU052_21080	ENOG4105BZU	Histidine kinase
CU052_21095	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CU052_21100	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
CU052_21155	ENOG4108ZJT	translation initiation factor, Sui1
CU052_21165	ENOG4105CPF	Cell wall formation (By similarity)
CU052_21175	ENOG4105CD5	CoA-binding domain protein
CU052_21185	ENOG4105CWB	LysR family transcriptional Regulator
CU052_21200	ENOG4105CMR	udp-glucose 4-epimerase
CU052_21205	ENOG4105BZU	Histidine kinase
CU052_21210	ENOG4105E7W	lamb ycsf family protein
CU052_21215	ENOG4105P4J	Allophanate hydrolase, subunit 1
CU052_21220	ENOG4107R7A	Allophanate hydrolase subunit 2
CU052_21230	ENOG4105CV6	ABC transporter, permease
CU052_21235	ENOG4108I0Y	(ABC) transporter
CU052_21245	ENOG4105RKW	reductase (By
CU052_21250	ENOG4105BZU	Histidine kinase
CU052_21260	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CU052_21295	ENOG4105KA0	thioesterase Superfamily protein
CU052_21310	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
CU052_21315	ENOG4108M0H	Extracellular lipase
CU052_21345	ENOG4105DU1	integral membrane protein, terc
CU052_21350	ENOG4105CGH	5'-nucleotidase
CU052_21355	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
CU052_21360	ENOG4108UQ5	membrane protein YcdZ
CU052_21365	ENOG4105DUM	transcriptional regulator, lysR family
CU052_21375	ENOG4105TMB	Formate nitrite transporter
CU052_21380	ENOG4108YYC	ycei family
CU052_21385	ENOG4105DS1	cytochrome b561
CU052_21400	ENOG4108M8H	domain protein
CU052_21405	ENOG4105C1J	atp-dependent rna helicase
CU052_21420	ENOG4108NVR	Methyl-accepting chemotaxis
CU052_21435	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CU052_21440	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CU052_21455	ENOG4107RE1	Inosine-guanosine kinase
CU052_21465	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CU052_21475	ENOG4105CF7	AraC family transcriptional regulator
CU052_21480	ENOG4108I6A	alcohol dehydrogenase
CU052_21490	ENOG4105CDA	abc transporter atp-binding protein
CU052_21495	ENOG4105E5Q	amino acid AbC transporter
CU052_21500	ENOG4106TNF	Periplasmic binding protein
CU052_21505	ENOG4105E5Q	amino acid AbC transporter
CU052_21510	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
CU052_21525	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
CU052_21530	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
CU052_21535	ENOG4105DE4	1-phosphofructokinase
CU052_21540	ENOG4105DM4	PTS System
CU052_21575	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
CU052_21585	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
CU052_21595	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CU052_21600	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CU052_21605	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CU052_21715	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CU052_21725	ENOG4105KVH	Transcriptional regulator
CU052_21740	ENOG4105BZ1	(ABC) transporter
CU052_21745	ENOG4107RGH	Aldehyde dehydrogenase
CU052_21765	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
CU052_21770	ENOG4105KPY	Small multidrug resistance protein
CU052_21785	ENOG4106CKV	Pap2 superfamily protein
CU052_21790	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CU052_21795	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
CU052_21800	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
CU052_21805	ENOG4105CCU	oxidase (Subunit III)
CU052_21810	ENOG4105BZ9	Cytochrome C oxidase, subunit I
CU052_21815	ENOG4105E2S	oxidase) subunit II
CU052_21825	ENOG4105CHR	reductase
CU052_21830	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CU052_21835	ENOG4105E39	Enoyl-CoA hydratase
CU052_21840	ENOG4105E39	Enoyl-CoA hydratase
CU052_21850	ENOG4105C26	Dehydrogenase
CU052_21855	ENOG4105CHU	acetyl-coa acetyltransferase
CU052_21865	ENOG4105C1G	acyl-Coa dehydrogenase
CU052_21870	ENOG4107QX3	carboxylase
CU052_21875	ENOG41060WC	Enoyl-CoA hydratase
CU052_21880	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
CU052_21915	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
CU052_21940	ENOG4105FR1	rard protein
CU052_21950	ENOG4108VAU	general secretion pathway protein G
CU052_21955	ENOG4107R88	Chemotaxis protein (CheV)
CU052_21965	ENOG4108TVJ	Nitroreductase
CU052_21970	ENOG4108NVR	Methyl-accepting chemotaxis
CU052_21975	ENOG4108WQH	regulatoR
CU052_21985	ENOG4105BZU	Histidine kinase
CU052_21990	ENOG4108WQH	regulatoR
CU052_21995	ENOG4105BZU	Histidine kinase
CU052_22000	ENOG4105BZU	Histidine kinase
CU052_22005	ENOG4105BZU	Histidine kinase
CU052_22015	ENOG4105D05	Receptor
CU052_22020	ENOG4105E0A	ABC, transporter
CU052_22025	ENOG4108U1V	ABC transporter, permease
CU052_22030	ENOG4105DQ5	transport system permease protein
CU052_22035	ENOG4108HUF	Transporter
CU052_22040	ENOG4105GAV	receptor
CU052_22045	ENOG4105E0K	tonB-dependent siderophore receptor
CU052_22065	ENOG4105DBM	Siderophore biosynthesis protein
CU052_22070	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
CU052_22075	ENOG4108ZKT	aldose 1-epimerase
CU052_22080	ENOG4108NZE	NAGC-like transcriptional regulator
CU052_22085	ENOG4107QNK	)-transporter
CU052_22090	ENOG4107HQ7	repeat protein
CU052_22110	ENOG4105DR5	peptidase
CU052_22115	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CU052_22120	ENOG4107KBT	8-Amino-7-oxononanoate synthase
CU052_22125	ENOG4108MGY	Histidine kinase
CU052_22145	ENOG4105CEE	C4-dicarboxylate transporter
CU052_22150	ENOG4108V0P	LemA family
CU052_22155	ENOG4105D0M	Protease HtpX homolog
CU052_22170	ENOG4105F2V	VRR-NUC domain-containing protein
CU052_22180	ENOG4105C4X	radical SAM domain protein
CU052_22200	ENOG4108YDI	single-species biofilm formation on inanimate substrate
CU052_22205	ENOG4107TE5	Lipid kinase
CU052_22210	ENOG41064T2	transcriptional regulator, lysR family
CU052_22215	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CU052_22220	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CU052_22225	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
CU052_22230	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
CU052_22235	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
CU052_22240	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CU052_22245	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
CU052_22250	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
CU052_22255	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
CU052_22290	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CU052_22300	ENOG4105ENH	Sulfatase
CU052_22305	ENOG4105ENH	Sulfatase
CU052_22315	ENOG410804D	Sensor Signal Transduction Histidine Kinase
CU052_22335	ENOG4105BZU	Histidine kinase
CU052_22340	ENOG4108SV3	Tmao reductase system periplasmic protein tort
CU052_22345	ENOG4108Z5K	methylglyoxal synthase
CU052_22350	ENOG41088T4	Helicase IV
CU052_22355	ENOG4105EM2	membrane
CU052_22390	ENOG4105VRT	cytoplasmic protein
CU052_22425	ENOG41090A4	Pterin carbinolamine dehydratase
CU052_22430	ENOG4105MIR	Phenylalanine 4-monooxygenase
CU052_22440	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
CU052_22445	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
CU052_22465	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
CU052_22475	ENOG4105C0A	alcohol dehydrogenase
CU052_22485	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
CU052_22495	ENOG4108RMU	ferritin dps family protein
CU052_22500	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_22525	ENOG4108MGY	Histidine kinase
CU052_22530	ENOG4105DFG	type I secretion outer membrane protein
CU052_22550	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CU052_22560	ENOG4107R39	(ABC) transporter
CU052_22580	ENOG4105BZU	Histidine kinase
CU052_22595	ENOG4105VEQ	Cold shock protein
CU052_22660	ENOG4108PCE	TRANSFER protein
CU052_22715	ENOG4105DZY	Pts system, glucitol sorbitol-specific
CU052_22720	ENOG410787A	Pts system, glucitol sorbitol-specific
CU052_22725	ENOG410804X	Transcriptional regulator
CU052_22730	ENOG4105J92	DNA-binding transcriptional activator GutM
CU052_22735	ENOG4107QMF	Sorbitol-6-phosphate dehydrogenase
CU052_22740	ENOG4105VI0	Pts system, glucitol sorbitol-specific
CU052_22745	ENOG4105DZY	Pts system, glucitol sorbitol-specific
CU052_22750	ENOG410787A	Pts system, glucitol sorbitol-specific
CU052_22755	ENOG4105C2X	Arabinose 5-phosphate isomerase
CU052_22800	ENOG4108UW8	fha domain-containing protein
CU052_22825	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CU052_22975	ENOG4105TNG	K13735 adhesin invasin
CU052_22985	ENOG4105BZV	Phosphoadenosine phosphosulfate reductase
CU052_22990	ENOG4105GTN	ParB Domain Protein Nuclease
CU052_23020	ENOG4105KAF	membrAne
CU052_23045	ENOG4105KK4	UPF0060 membrane protein
CU052_23050	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CU052_23060	ENOG4108ZG0	Ompa motb domain protein
CU052_23070	ENOG4108V1T	peptidylprolyl cis-trans isomerase
CU052_23100	ENOG4107VXZ	Hydrolase
CU052_23105	ENOG4108YZN	class I peptide chain release factor
CU052_23110	ENOG4108N3W	hemolysin secretion protein
CU052_23125	ENOG4107YWA	deoxycytidylate deaminase
CU052_23130	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CU052_23145	ENOG4105WH1	Two component transcriptional regulator luxr family
CU052_23150	ENOG4105BZU	Histidine kinase
CU052_23165	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
CU052_23175	ENOG4105CUW	cytochrome C-TYPE protein
CU052_23190	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
CU052_23200	ENOG4105CHU	acetyl-coa acetyltransferase
CU052_23220	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CU052_23225	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CU052_23255	ENOG4105EW9	transcriptional regulator AsnC family
CU052_23270	ENOG4105BZU	Histidine kinase
CU052_23275	ENOG4108QGH	periplasmic
CU052_23280	ENOG41082IR	Excinuclease ABC C subunit domain protein
CU052_23285	ENOG4108YXG	UPF0502 protein
CU052_23295	ENOG41090HJ	UPF0265 protein
CU052_23300	ENOG4105C3S	Mate efflux family protein
CU052_23305	ENOG4105EE0	oxidoreductase
CU052_23310	ENOG4105EQR	Transposase IS116 IS110 IS902
CU052_23315	ENOG4105BZU	Histidine kinase
CU052_23345	ENOG4108XM1	transcriptional regulator AsnC family
CU052_23350	ENOG4105DVH	amino acid
CU052_23355	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CU052_23365	ENOG4105E0F	Histidine kinase
CU052_23370	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CU052_23395	ENOG4105EFX	secretion protein, HlyD family
CU052_23400	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
CU052_23405	ENOG4105CJW	magnesium transporter
CU052_23410	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
CU052_23415	ENOG4105DZC	cytosine deaminase
CU052_23430	ENOG4105EST	Metal Dependent Phosphohydrolase
CU052_23445	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
CU052_23455	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CU052_23475	ENOG4108Z33	Thiol disulfide Interchange Protein
CU052_23490	ENOG4105EMU	Dehydrogenase
CU052_23505	ENOG4107EFR	Flavocytochrome c
CU052_23510	ENOG4105DIA	mandelate racemase muconate lactonizing
CU052_23515	ENOG4105C94	Transporter
CU052_23520	ENOG4107EXC	regulatoR
CU052_23525	ENOG4105JJR	Histidine kinase
CU052_23535	ENOG41080IJ	Diacylglycerol kinase
CU052_23540	ENOG4105DIJ	Phosphoethanolamine transferase
CU052_23545	ENOG4105EP9	oxidoreductase
CU052_23550	ENOG4105ECQ	AraC Family Transcriptional Regulator
CU052_23555	ENOG4108W2Y	isochorismatase
CU052_23625	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CU052_23630	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
CU052_23635	ENOG4105QVC	MOSC domain-containing protein
CU052_23635	ENOG4105QVC	MOSC domain-containing protein
CU052_23650	ENOG4105EKE	dihydroorotase
CU052_23655	ENOG4105CKW	Inner membrane protein yedI
CU052_23665	ENOG4105EQD	regulatoR
CU052_23680	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
CU052_23725	ENOG4105EG2	ABC transporter, permease
CU052_23730	ENOG4105D56	permease protein
CU052_23735	ENOG4107FKK	extracellular solute-binding protein family 1
CU052_23745	ENOG4108IJ9	(ABC) transporter
CU052_23765	ENOG4108F2G	Chain length determinant protein
CU052_23775	ENOG4107TYR	Glycosyl Transferase
CU052_23800	ENOG4105V0I	UPF0267 protein
CU052_23805	ENOG4108WUH	Transcriptional regulator, TetR family
CU052_23810	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
CU052_23820	ENOG4105CH6	catalase
CU052_23825	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CU052_23835	ENOG4105CBN	LysR family transcriptional regulator
CU052_23840	ENOG4105DM4	PTS System
CU052_23845	ENOG4108YRF	PTS System
CU052_23855	ENOG4106R3P	AraC family transcriptional regulator
CU052_23860	ENOG4105DM4	PTS System
CU052_23865	ENOG4105EIP	mannose-6-phosphate isomerase
CU052_23875	ENOG4105G2Y	Transcriptional regulator
CU052_23880	ENOG4105EFX	secretion protein, HlyD family
CU052_23885	ENOG4105FP6	Protein of unknown function (DUF3302)
CU052_23915	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CU052_23925	ENOG4105EJC	lysr family transcriptional regulator
CU052_23930	ENOG410874W	AraC family transcriptional regulator
CU052_23935	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CU052_23955	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
CU052_23975	ENOG4105C1J	atp-dependent rna helicase
CU052_23990	ENOG4105HEI	LysR family (Transcriptional regulator
CU052_24015	ENOG4105CHR	reductase
CU052_24020	ENOG4105F27	Major Facilitator
CU052_24030	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CU052_24045	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
CU052_24070	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CU052_24080	ENOG4105HDK	L-asparaginase
CU052_24085	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
CU052_24090	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CU052_24100	ENOG4108S01	response regulator
CU052_24105	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CU052_24120	ENOG4105HEI	LysR family (Transcriptional regulator
CU052_24125	ENOG4107V40	secretion protein, HlyD family
CU052_24135	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
CU052_24140	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
CU052_24145	ENOG4105D6U	Sodium Glutamate Symporter
CU052_24160	ENOG4105BZU	Histidine kinase
CU052_24170	ENOG41086KC	Transcriptional regulator
CU052_24235	ENOG4105BZS	acriflavin resistance protein
CU052_24245	ENOG4107RZC	phospholipase d
CU052_24280	ENOG4108Z4X	TRANSCRIPTIONal
CU052_24285	ENOG4108UHE	carbonic anhydrase
CU052_24290	ENOG41090VV	Protein of unknown function (DUF2846)
CU052_24315	ENOG4105CPQ	Dehydrogenase
CU052_24320	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CU052_24325	ENOG4105BZU	Histidine kinase
CU052_24330	ENOG4106PMH	Extracellular solute-binding protein family 3
CU052_24345	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CU052_24365	ENOG4105EXG	Transcriptional regulator
CU052_24370	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
CU052_24390	ENOG4107SSZ	Phosphatase
CU052_24415	ENOG4105BZU	Histidine kinase
CU052_24425	ENOG4108JIR	Flagellum-specific ATP synthase
CU052_24435	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CU052_24440	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
CU052_24450	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CU052_24465	ENOG4105DD5	Flagellar motor switch protein
CU052_24470	ENOG4105CN7	Flagellar biosynthetic protein FliP
CU052_24475	ENOG4105VS8	Flagellar biosynthetic protein fliq
CU052_24480	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CU052_24485	ENOG4105D00	flagellar biosynthetic protein flhB
CU052_24500	ENOG4105I03	Flagellin
CU052_24510	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
CU052_24515	ENOG4105MQ3	flagellar protein FliS
CU052_24540	ENOG4107RD7	Flagellar Motor Protein, MotA
CU052_24545	ENOG4105ER2	Ompa motb domain protein
CU052_24570	ENOG4105KWG	Pfam:DUF1696
CU052_24580	ENOG4105F87	Dehydratase
CU052_24595	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CU052_24610	ENOG4107XPZ	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
CU052_24620	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CU052_24635	ENOG4107SJW	iron permease, FTR1
CU052_24655	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
CU052_24670	ENOG4108M3R	transcriptional activator CadC
CU052_24675	ENOG4105EE5	Membrane protein terC
CU052_24690	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
CU052_24710	ENOG4105DTJ	flagellar hook-associated protein
CU052_24715	ENOG4105E1Q	flagellar hook-associated protein
CU052_24720	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
CU052_24725	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CU052_24730	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
CU052_24735	ENOG4105CGA	flagellar basal-body rod protein FlgG
CU052_24740	ENOG4108KPB	Flagellar basal-body rod protein FlgF
CU052_24745	ENOG4105BZE	flagellar hook protein, FlgE
CU052_24750	ENOG4105W00	Flagellar hook capping protein
CU052_24755	ENOG4108ZC9	flagellar basal-body rod protein flgc
CU052_24760	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
CU052_24780	ENOG4105E9H	Lytic Murein transglycosylase
CU052_24815	ENOG4105EJQ	L-serine dehydratase
CU052_24820	ENOG4105DUX	Transporter
CU052_24825	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
CU052_24845	ENOG4105ETT	transcriptional Regulator, LysR family
CU052_24860	ENOG4105CJP	fad dependent oxidoreductase
CU052_24875	ENOG4108MJ5	VirK protein
CU052_24895	ENOG4107RCV	ABC transporter, permease
CU052_24910	ENOG4107STF	Involved in phosphonate degradation (By similarity)
CU052_24915	ENOG4108JPW	Aminotransferase
CU052_24920	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
CU052_24925	ENOG4105ETE	Transcriptional regulator (LacI family
CU052_24950	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CU052_24955	ENOG4105KUU	lipolytic protein G-D-S-L family
CU052_24990	ENOG4105PAD	Hydrolase
CU052_24995	ENOG4105JQN	Transcriptional regulator
CU052_25040	ENOG4108UKZ	OsmC family
CU052_25070	ENOG4108UKZ	OsmC family
CU052_25075	ENOG4105E0X	reductase
CU052_25090	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
CU052_25095	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CU052_25100	ENOG4106TD9	Diguanylate cyclase
CU052_25115	ENOG4105BZU	Histidine kinase
CU052_25140	ENOG4105D9N	nucleoside
CU052_25160	ENOG4105C0F	tryptophanase EC 4.1.99.1
CU052_25165	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
CU052_25180	ENOG4105NVB	glycoside hydrolase, family 19
CU052_25190	ENOG4105D5U	fad dependent oxidoreductase
CU052_25215	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
CU052_25220	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CU052_25225	ENOG4105CQZ	Histidine kinase
CU052_25255	ENOG4108WAV	Transcriptional regulator
CU052_25280	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CU052_25285	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
CU052_25295	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
CU052_25300	ENOG4105CYW	agmatinase
CU052_25305	ENOG4105E5M	Multidrug resistance protein D
CU052_25310	ENOG4105CUG	Oligopeptidase b
CU052_25330	ENOG4105CC5	ABC transporter
CU052_25335	ENOG4105DIK	(ABC) transporter
CU052_25340	ENOG4105DSE	periplasmic solute binding protein
CU052_25385	ENOG4109015	Biopolymer transport protein exbD tolR
CU052_25410	ENOG410804D	Sensor Signal Transduction Histidine Kinase
CU052_25415	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CU052_25420	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CU052_25425	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
CU052_25435	ENOG4105C5I	Dehydrogenase
CU052_25440	ENOG4108YYI	Protein of unknown function (DUF2810)
CU052_25485	ENOG4108TEM	pseudouridine methyltransferase
CU052_25500	ENOG4105DWF	phosphomethylpyrimidine kinase
CU052_25505	ENOG4108YI8	ABC transporter
CU052_25510	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
CU052_25515	ENOG4107Z6I	Thiamine biosynthesis protein
CU052_25520	ENOG4105ETU	transcriptional activator (TenA
CU052_25525	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
CU052_25530	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CU052_25535	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
CU052_25540	ENOG4107QY8	reductase
CU052_25545	ENOG4105CUW	cytochrome C-TYPE protein
CU052_25575	ENOG4108W0I	acetyltransferase
CU052_25620	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CU052_25625	ENOG4108K8S	endonuclease I
CU052_25645	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
CU052_25655	ENOG4105BZU	Histidine kinase
CU052_25665	ENOG4105D5B	Sulfite reductase, subunit A
CU052_25670	ENOG4107SHJ	sulfite reductase subunit b
CU052_25675	ENOG410810Y	Sulfite reductase
CU052_25680	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
CU052_25695	ENOG4105E5M	Multidrug resistance protein D
CU052_25715	ENOG4105D05	Receptor
CU052_25730	ENOG4105DHS	permease protein
CU052_25735	ENOG4105CM4	permease protein
CU052_25740	ENOG4108IPW	abc transporter atp-binding protein
CU052_25745	ENOG41062JF	Transcriptional regulator
CU052_25765	ENOG4105DR5	peptidase
CU052_25790	ENOG4107RAN	Peptidase, M16
CU052_25795	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_25810	ENOG4108ZHJ	Organic hydroperoxide resistance protein
CU052_25815	ENOG4105K56	Transcriptional regulator
CU052_25825	ENOG4105D3R	alkyl hydroperoxide reductase
CU052_25830	ENOG4108JU3	Alkyl hydroperoxide reductase
CU052_25865	ENOG4105HEI	LysR family (Transcriptional regulator
CU052_25870	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
CU052_25885	ENOG4105C5Q	Transcriptional regulator
CU052_25900	ENOG4107FKK	extracellular solute-binding protein family 1
CU052_25935	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
CU052_25940	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_25955	ENOG4108XM1	transcriptional regulator AsnC family
CU052_25970	ENOG4108RPX	mosc domain containing protein
CU052_25975	ENOG4107YB6	acetyltransferase, (GNAT) family
CU052_25985	ENOG4105RW8	MltA-interacting MipA family protein
CU052_25990	ENOG4105C1J	atp-dependent rna helicase
CU052_26000	ENOG410904A	RNA polymerase
CU052_26005	ENOG4105C87	Aminotransferase class I and II
CU052_26020	ENOG4105VMP	Transcriptional regulator
CU052_26025	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
CU052_26030	ENOG4105C6F	GntR Family Transcriptional Regulator
CU052_26035	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CU052_26040	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
CU052_26045	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CU052_26050	ENOG4105DEI	Mannitol dehydrogenase
CU052_26060	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
CU052_26065	ENOG4108UHU	Aldolase
CU052_26070	ENOG4105P66	Membrane
CU052_26075	ENOG4105EJ2	Transcriptional regulator
CU052_26085	ENOG410839U	amino acid
CU052_26115	ENOG4105VG5	Membrane
CU052_26120	ENOG4105CBG	Sulfatase
CU052_26135	ENOG4108UHU	Aldolase
CU052_26140	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
CU052_26145	ENOG4105CHR	reductase
CU052_26150	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
CU052_26160	ENOG4105EP8	Glycosyl Hydrolase Family 88
CU052_26165	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
CU052_26170	ENOG4105C4X	radical SAM domain protein
CU052_26180	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CU052_26195	ENOG4105BZ1	(ABC) transporter
CU052_26205	ENOG4105EW9	transcriptional regulator AsnC family
CU052_26255	ENOG4105CK7	Sodium proline symporter
CU052_26265	ENOG4105C26	Dehydrogenase
CU052_26280	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
CU052_26285	ENOG4105CQZ	Histidine kinase
CU052_26290	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CU052_26295	ENOG4107QZV	Type I secretion membrane fusion protein
CU052_26310	ENOG4108JJA	ABC, transporter
CU052_26330	ENOG4108J59	Extracellular solute-binding protein, family 5
CU052_26360	ENOG4108SF5	RNA Polymerase
CU052_26395	ENOG4105CWK	Biopolymer transport protein, ExbB
CU052_26400	ENOG4108ZZF	transport protein (ExbD)
CU052_26405	ENOG41067XB	TonB family
CU052_26410	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
CU052_26415	ENOG4106RMF	ParB family
CU052_26435	ENOG4108JQ7	(ABC) transporter
CU052_26460	ENOG4105BZU	Histidine kinase
CU052_26470	ENOG4105CDY	transcriptional regulatory protein
CU052_26475	ENOG4105CNI	cell division protein FtsW
CU052_26490	ENOG4105Y49	secretion protein, HlyD family
CU052_26495	ENOG4105CR8	Transcriptional regulator
CU052_26515	ENOG410607W	Transposase
CU052_26545	ENOG4108HRK	Histidine kinase
CU052_26550	ENOG4108VAC	response regulator
CU052_26560	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
CU052_26565	ENOG4105C8Q	Methyl-accepting chemotaxis
CU052_26585	ENOG4105D6U	Sodium Glutamate Symporter
CU052_26600	ENOG4105CZV	ABC transporter
CU052_26605	ENOG4107U9B	transcriptional regulator
CU052_26610	ENOG4105D6U	Sodium Glutamate Symporter
CU052_26640	ENOG4108K4B	hydrolase
CU052_26650	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
CU052_26670	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
CU052_26690	ENOG4108VGI	doxx family
CU052_26700	ENOG4105D03	DNA-3-methyladenine glycosylase II
CU052_26705	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CU052_26740	ENOG4105C19	ABC transporter
CU052_26750	ENOG4105E98	transcriptional regulator DeoR family
CU052_26755	ENOG4105E98	transcriptional regulator DeoR family
CU052_26760	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
CU052_26765	ENOG4105E70	isomerase
CU052_26770	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
CU052_26780	ENOG4105F3R	pts system mannose fructose sorbose family iid
CU052_26785	ENOG4108YTN	IIa component
CU052_26790	ENOG4105CE4	GlcNAc 6-P deacetylase
CU052_26795	ENOG4105D2N	Aldolase
CU052_26805	ENOG4105CFP	Peptidase U32
CU052_26840	ENOG4105DN9	Na H antiporter
CU052_26870	ENOG4105NBK	UPF0345 protein
CU052_26880	ENOG4108K0B	C-di-gmp phosphodiesterase
CU052_26885	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
CU052_26890	ENOG41060NJ	transcriptional regulator
CU052_26905	ENOG4105DRS	transport system, permease
CU052_26915	ENOG4108IJ9	(ABC) transporter
CU052_26920	ENOG4105ETE	Transcriptional regulator (LacI family
CU052_26925	ENOG4105UQX	Mate efflux family protein
CU052_26930	ENOG4105D3G	Pseudouridine synthase
CU052_26935	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CU052_26945	ENOG4108HCJ	Hydrolase
CU052_26955	ENOG4108KHX	Diguanylate cyclase
CU052_26965	ENOG4105KAF	membrAne
CU052_26995	ENOG4105CC0	LysR family Transcriptional regulator
CU052_27000	ENOG4105Q26	Siderophore-interacting protein
CU052_27015	ENOG4105EW9	transcriptional regulator AsnC family
CU052_27020	ENOG4108M1A	Chitin-binding protein
CU052_27030	ENOG410814C	multidrug resistance protein
CU052_27055	ENOG4107W31	Pentapeptide repeat protein
CU052_27060	ENOG4105EIF	outer membrane protein W
CU052_27080	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
CU052_27115	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
CU052_27140	ENOG4107ZSV	Receptor
CU052_27145	ENOG4105BZ1	(ABC) transporter
CU052_27150	ENOG4105BZ1	(ABC) transporter
CU052_27240	ENOG4105G2Y	Transcriptional regulator
CU052_27260	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
CU052_27285	ENOG4105CI2	imidazolone-5-propionate hydrolase
CU052_27295	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
CU052_27300	ENOG4105BZW	Glycerate kinase
CU052_27320	ENOG4105CXN	decarboxylase
CU052_27325	ENOG4105D5Q	Arginine ornithine antiporter
CU052_27335	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
CU052_27355	ENOG4105CHU	acetyl-coa acetyltransferase
CU052_27360	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
CU052_27370	ENOG4105HEI	LysR family (Transcriptional regulator
CU052_27375	ENOG4107QNK	)-transporter
CU052_27385	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
CU052_27390	ENOG4105CIB	oxidoreductase Domain protein
CU052_27395	ENOG4105EDK	PfkB domain protein
CU052_27425	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
CU052_27430	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CU052_27435	ENOG4105CI1	PTS System
CU052_27460	ENOG41061ZR	Transcriptional regulator
CU052_27470	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
CU052_27480	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
CU052_27485	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CU052_27490	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
CU052_27495	ENOG4107T9C	Alpha amylase catalytic region
CU052_27510	ENOG41074DU	domain protein
CU052_27515	ENOG4108P2H	Inner membrane protein YjiG
CU052_27520	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
CU052_27540	ENOG4105CK2	sodium dicarboxylate symporter
CU052_27575	ENOG4105C5Q	Transcriptional regulator
CU052_27580	ENOG4105N0V	mono-oxygenase ydhR
CU052_27590	ENOG4105D75	Capsular exopolysaccharide family
CU052_27600	ENOG4105DAY	polysaccharide export protein
CU052_27610	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
CU052_27615	ENOG4107EDW	L-fucose operon activator
CU052_27620	ENOG4105EDR	glucose galactose transporter
CU052_27630	ENOG4105CMG	Carbohydrate kinase
CU052_27635	ENOG4105NWF	RbsD or FucU transport
CU052_27640	ENOG4107W7X	Aldolase
CU052_27645	ENOG4105C0A	alcohol dehydrogenase
CU052_27680	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
CU052_27690	ENOG4105C72	UPF0176 protein
CU052_27695	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CU052_27700	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
CU052_27720	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CU052_27735	ENOG4105DZ1	carboxypeptidase
CU052_27750	ENOG4108RCM	Nitroreductase
CU052_27760	ENOG4105EJC	lysr family transcriptional regulator
CU052_27765	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
CU052_27775	ENOG4105DP0	ferredoxin-NADP reductase
CU052_27790	ENOG41068P6	UPF0319 protein
CU052_27795	ENOG4105IPI	Membrane
CU052_27835	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
CU052_27850	ENOG4105G2Y	Transcriptional regulator
CU052_27855	ENOG4105CNH	Multidrug resistance protein MdtL
CU052_27865	ENOG4105I4A	GCN5-related N-acetyltransferase
CU052_27875	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
CU052_27880	ENOG4105EB3	Histidine kinase
CU052_27895	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
CU052_27935	ENOG4105C4M	(Ubiquinol oxidase) subunit I
CU052_27950	ENOG4105E18	UPF0276 protein
CU052_27965	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
CU052_27970	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
CU052_27985	ENOG4105C5H	ABC transporter
CU052_27990	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
CU052_27995	ENOG4105HEI	LysR family (Transcriptional regulator
CU052_28000	ENOG4105Q8W	reductase
CU052_28005	ENOG4105CHF	Glutathione S-transferase
CU052_28010	ENOG4105C5H	ABC transporter
CU052_28025	ENOG4105HEI	LysR family (Transcriptional regulator
CU052_28030	ENOG4105W1N	transcriptional regulator
CU052_28045	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
CU052_28050	ENOG4105N14	lysine exporter protein LysE YggA
CU052_28130	ENOG4108ZHR	arsR family transcriptional regulator
CU052_28210	ENOG4108YGG	dna repair protein
CU052_28265	ENOG4105R8V	Transcriptional regulator
CU052_28450	ENOG4105CNA	YD repeat protein
CU052_28525	ENOG4107W31	Pentapeptide repeat protein
CU052_28575	ENOG4107QJE	Chromosome Partitioning Protein
CU052_28680	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CU052_28765	ENOG4105T95	Thiol disulfide interChange protein
CU052_28780	ENOG4105C3F	Signal peptidase i
CU052_28830	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
CU052_28890	ENOG4105XPH	Ferredoxin
CU052_28925	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
CU052_28980	ENOG4105DK2	UPF0207 protein
CU052_29085	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CU052_29120	ENOG4106PHI	plasmid recombination enzyme
CU052_29145	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)