locus-tag	class	description
CU052_00045	COG2801	Transposase and inactivated derivatives
CU052_00060	COG3692	DNA binding
CU052_00160	COG1475	DNA binding
CU052_00425	COG1132	(ABC) transporter
CU052_00450	COG4591	ABC-type transport system involved in lipoprotein release permease component
CU052_00455	COG1136	(ABC) transporter
CU052_00460	COG4591	ABC-type transport system involved in lipoprotein release permease component
CU052_00470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CU052_00485	COG1252	NADH dehydrogenase
CU052_00515	COG0537	adenosine 5'-monophosphoramidase activity
CU052_00535	COG2217	Heavy metal translocating P-type atpase
CU052_00545	COG0516	GMP reductase activity
CU052_00545	COG0517	IMP dehydrogenase activity
CU052_00550	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CU052_00555	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CU052_00560	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CU052_00565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CU052_00575	COG3706	GGDEF domain
CU052_00590	COG3126	Type III secretion system lipoprotein chaperone (YscW)
CU052_00595	COG1946	Acyl-CoA thioesterase
CU052_00605	COG1522	sequence-specific DNA binding
CU052_00705	COG2433	Pfam Transposase IS66
CU052_00735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU052_00790	COG2855	membrane
CU052_00805	COG0583	DNA-binding transcription factor activity
CU052_00810	COG1263	PTS System
CU052_00810	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU052_00810	COG2190	(PTS) system
CU052_00820	COG1441	menaquinone biosynthetic process
CU052_00825	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CU052_00830	COG0596	Alpha beta hydrolase
CU052_00840	COG1169	isochorismate synthase
CU052_00845	COG0436	Aminotransferase
CU052_00850	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CU052_00885	COG2433	Pfam Transposase IS66
CU052_00905	COG2091	lysine biosynthetic process via aminoadipic acid
CU052_00920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CU052_00940	COG1136	(ABC) transporter
CU052_00945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU052_00960	COG0154	amidase activity
CU052_01005	COG1250	3-hydroxyacyl-CoA dehydrogenase
CU052_01015	COG0318	PFAM AMP-dependent synthetase and ligase
CU052_01015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CU052_01015	COG0300	oxidoreductase activity
CU052_01015	COG1028	Short-chain dehydrogenase reductase Sdr
CU052_01015	COG3321	synthase
CU052_01050	COG2801	Transposase and inactivated derivatives
CU052_01060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CU052_01065	COG0776	regulation of translation
CU052_01070	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CU052_01105	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CU052_01110	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CU052_01115	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CU052_01130	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CU052_01135	COG0569	domain protein
CU052_01140	COG0513	Belongs to the DEAD box helicase family
CU052_01145	COG1253	flavin adenine dinucleotide binding
CU052_01150	COG4771	TonB-dependent receptor
CU052_01165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CU052_01165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CU052_01170	COG3433	isochorismatase activity
CU052_01170	COG1535	isochorismatase
CU052_01175	COG1021	2,3-dihydroxybenzoate-AMP ligase
CU052_01180	COG1169	isochorismate synthase
CU052_01190	COG1028	Short-chain dehydrogenase reductase Sdr
CU052_01230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CU052_01235	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CU052_01255	COG1216	Glycosyl transferase, family 2
CU052_01260	COG2986	histidine ammonia-lyase
CU052_01290	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CU052_01295	COG1028	Short-chain dehydrogenase reductase Sdr
CU052_01330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CU052_01340	COG2951	lytic endotransglycosylase activity
CU052_01355	COG2894	cell division
CU052_01360	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CU052_01365	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
CU052_01370	COG0318	PFAM AMP-dependent synthetase and ligase
CU052_01375	COG2267	carboxylic ester hydrolase activity
CU052_01380	COG3065	identical protein binding
CU052_01390	COG1214	PFAM Peptidase M22, glycoprotease
CU052_01395	COG1199	ATP-dependent helicase activity
CU052_01400	COG0788	formyltetrahydrofolate deformylase activity
CU052_01405	COG3102	Protein conserved in bacteria
CU052_01435	COG1918	ferrous iron import across plasma membrane
CU052_01440	COG4977	sequence-specific DNA binding
CU052_01445	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
CU052_01450	COG1121	(ABC) transporter
CU052_01455	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CU052_01470	COG0508	dehydrogenase complex catalyzes the overall conversion of
CU052_01475	COG0567	Dehydrogenase, E1 component
CU052_01485	COG1053	succinate dehydrogenase
CU052_01490	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CU052_01495	COG2009	succinate dehydrogenase
CU052_01505	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CU052_01520	COG0033	Phosphoglucomutase
CU052_01530	COG0596	Alpha beta hydrolase
CU052_01540	COG0716	FMN binding
CU052_01550	COG0735	belongs to the Fur family
CU052_01565	COG2190	(PTS) system
CU052_01565	COG1263	PTS System
CU052_01565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU052_01575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
CU052_01580	COG1846	Transcriptional regulator
CU052_01580	COG1940	carbohydrate kinase activity
CU052_01585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CU052_01585	COG4651	solute:proton antiporter activity
CU052_01590	COG0367	asparagine synthase
CU052_01600	COG2801	Transposase and inactivated derivatives
CU052_01605	COG3104	oligopeptide transport
CU052_01610	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CU052_01625	COG3710	Transcriptional regulator
CU052_01645	COG0622	Phosphoesterase
CU052_01675	COG1090	epimerase
CU052_01680	COG0300	oxidoreductase activity
CU052_01690	COG3118	belongs to the thioredoxin family
CU052_01695	COG0330	HflC and HflK could
CU052_01740	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
CU052_01745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CU052_01755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_01760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CU052_01765	COG2190	(PTS) system
CU052_01770	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CU052_01775	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CU052_01780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CU052_01795	COG1705	Flagellar rod assembly protein muramidase FlgJ
CU052_01795	COG3951	Flagellar rod assembly protein muramidase FlgJ
CU052_01800	COG1706	bacterial-type flagellum-dependent cell motility
CU052_01805	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CU052_01810	COG4786	Flagellar basal body rod
CU052_01815	COG4787	bacterial-type flagellum-dependent cell motility
CU052_01825	COG1749	Flagellar hook protein flgE
CU052_01830	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CU052_01835	COG1558	bacterial-type flagellum-dependent cell motility
CU052_01840	COG1815	bacterial-type flagellum-dependent cell motility
CU052_01845	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CU052_01850	COG0835	chemotaxis
CU052_01850	COG0784	Response regulator, receiver
CU052_01905	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CU052_01920	COG2608	mercury ion transmembrane transporter activity
CU052_01920	COG2217	Heavy metal translocating P-type atpase
CU052_01965	COG2840	Smr protein MutS2
CU052_01970	COG1187	pseudouridine synthase activity
CU052_01975	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CU052_01980	COG0737	Belongs to the 5'-nucleotidase family
CU052_01985	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CU052_01990	COG2912	Transglutaminase-like superfamily
CU052_01995	COG3094	Invasion gene expression up-regulator, SirB
CU052_02000	COG2890	protein-(glutamine-N5) methyltransferase activity
CU052_02025	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CU052_02140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CU052_02155	COG1702	phosphate starvation-inducible protein PhoH
CU052_02165	COG4535	Mg2 and Co2 transporter CorC
CU052_02170	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CU052_02175	COG2888	peptidyl-tyrosine sulfation
CU052_02185	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
CU052_02190	COG1466	dna polymerase III delta subunit
CU052_02195	COG0799	negative regulation of ribosome biogenesis
CU052_02205	COG0768	penicillin binding
CU052_02210	COG0772	Belongs to the SEDS family
CU052_02215	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CU052_02220	COG1686	Belongs to the peptidase S11 family
CU052_02240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CU052_02245	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CU052_02260	COG0366	Alpha amylase catalytic
CU052_02265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU052_02265	COG1263	PTS System
CU052_02275	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CU052_02280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CU052_02285	COG2011	ABC-type metal ion transport system permease component
CU052_02290	COG1464	Belongs to the NlpA lipoprotein family
CU052_02305	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
CU052_02325	COG3706	GGDEF domain
CU052_02330	COG1611	Belongs to the LOG family
CU052_02350	COG2363	Small membrane protein
CU052_02360	COG0583	DNA-binding transcription factor activity
CU052_02375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CU052_02385	COG0142	geranyltranstransferase activity
CU052_02395	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CU052_02400	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CU052_02425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CU052_02425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CU052_02430	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CU052_02435	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CU052_02455	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
CU052_02460	COG2252	PERMEase
CU052_02465	COG2195	Cleaves the N-terminal amino acid of tripeptides
CU052_02495	COG0047	phosphoribosylformylglycinamidine synthase activity
CU052_02495	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CU052_02510	COG0590	tRNA wobble adenosine to inosine editing
CU052_02515	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CU052_02520	COG2801	Transposase and inactivated derivatives
CU052_02565	COG1301	dicarboxylic acid transport
CU052_02585	COG0497	DNA recombination
CU052_02590	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CU052_02595	COG2914	Belongs to the UPF0125 (RnfH) family
CU052_02600	COG2867	negative regulation of translational initiation
CU052_02615	COG0582	viral genome integration into host DNA
CU052_02655	COG2003	Belongs to the UPF0758 family
CU052_02695	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CU052_02720	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CU052_02750	COG0583	DNA-binding transcription factor activity
CU052_02755	COG1289	transmembrane transporter activity
CU052_02775	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CU052_02795	COG0719	Fe-S assembly protein
CU052_02800	COG0396	ATPase activity
CU052_02805	COG0719	Fe-S assembly protein
CU052_02810	COG0316	Belongs to the HesB IscA family
CU052_02815	COG2873	o-acetylhomoserine
CU052_02820	COG0668	transmembrane transport
CU052_02825	COG0583	DNA-binding transcription factor activity
CU052_02835	COG1115	amino acid carrier protein
CU052_02840	COG1584	GPR1 FUN34 yaaH family protein
CU052_02850	COG1757	Na H antiporter
CU052_02860	COG0516	GMP reductase activity
CU052_02860	COG0517	IMP dehydrogenase activity
CU052_02875	COG2199	diguanylate cyclase activity
CU052_02875	COG2203	Gaf domain
CU052_02890	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CU052_02895	COG2976	Protein conserved in bacteria
CU052_02930	COG2975	iron-sulfur cluster assembly
CU052_02935	COG0633	Ferredoxin
CU052_02950	COG0316	Belongs to the HesB IscA family
CU052_02955	COG0822	iron-sulfur transferase activity
CU052_02970	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
CU052_02975	COG0483	inositol monophosphate 1-phosphatase activity
CU052_02990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CU052_02995	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CU052_03000	COG1862	Preprotein translocase
CU052_03025	COG0517	IMP dehydrogenase activity
CU052_03035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CU052_03040	COG0583	DNA-binding transcription factor activity
CU052_03045	COG0450	alkyl hydroperoxide reductase
CU052_03075	COG0704	Plays a role in the regulation of phosphate uptake
CU052_03080	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CU052_03085	COG0581	inorganic phosphate transmembrane transporter activity
CU052_03090	COG0573	inorganic phosphate transmembrane transporter activity
CU052_03095	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CU052_03100	COG0248	Ppx GppA phosphatase
CU052_03110	COG5002	protein histidine kinase activity
CU052_03115	COG0745	RESPONSE REGULATOR receiver
CU052_03130	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CU052_03140	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
CU052_03200	COG0542	response to heat
CU052_03210	COG0564	pseudouridine synthase activity
CU052_03215	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CU052_03220	COG0741	lytic transglycosylase activity
CU052_03225	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CU052_03230	COG1605	Chorismate mutase
CU052_03230	COG0077	Prephenate dehydratase
CU052_03235	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
CU052_03250	COG0488	(ABC) transporter
CU052_03260	COG0739	heme binding
CU052_03265	COG0287	Prephenate dehydrogenase
CU052_03265	COG1605	Chorismate mutase
CU052_03270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CU052_03275	COG1472	Belongs to the glycosyl hydrolase 3 family
CU052_03280	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CU052_03310	COG1966	Carbon starvation protein
CU052_03315	COG3275	phosphorelay sensor kinase activity
CU052_03320	COG3279	Response regulator of the LytR AlgR family
CU052_03325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CU052_03330	COG1047	Peptidyl-prolyl cis-trans
CU052_03345	COG0196	riboflavin kinase activity
CU052_03350	COG0728	peptidoglycan biosynthetic process
CU052_03355	COG0268	Binds directly to 16S ribosomal RNA
CU052_03360	COG0640	Transcriptional regulator
CU052_03365	COG0583	DNA-binding transcription factor activity
CU052_03370	COG1283	sodium-dependent phosphate transmembrane transporter activity
CU052_03385	COG0730	response to heat
CU052_03390	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
CU052_03410	COG0667	Aldo Keto reductase
CU052_03435	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CU052_03440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CU052_03450	COG0716	FMN binding
CU052_03465	COG0513	Belongs to the DEAD box helicase family
CU052_03475	COG3022	response to hydroperoxide
CU052_03480	COG1115	amino acid carrier protein
CU052_03515	COG0431	NADPH-dependent FMN reductase
CU052_03520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CU052_03525	COG0083	homoserine kinase activity
CU052_03540	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CU052_03555	COG0745	RESPONSE REGULATOR receiver
CU052_03565	COG0784	Response regulator, receiver
CU052_03565	COG5002	protein histidine kinase activity
CU052_03565	COG2198	Histidine kinase
CU052_03575	COG2203	Gaf domain
CU052_03575	COG3706	GGDEF domain
CU052_03575	COG5001	Diguanylate cyclase
CU052_03575	COG4251	negative regulation of phosphorylation
CU052_03585	COG2801	Transposase and inactivated derivatives
CU052_03595	COG0069	glutamate synthase activity
CU052_03595	COG0067	glutamate synthase
CU052_03595	COG0070	glutamate synthase
CU052_03605	COG0070	glutamate synthase
CU052_03605	COG0067	glutamate synthase
CU052_03605	COG0069	glutamate synthase activity
CU052_03610	COG0493	'glutamate synthase
CU052_03635	COG2860	membrane
CU052_03640	COG0583	DNA-binding transcription factor activity
CU052_03645	COG0730	response to heat
CU052_03665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CU052_03670	COG0505	Belongs to the CarA family
CU052_03680	COG0494	nUDIX hydrolase
CU052_03695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CU052_03700	COG0849	cell division
CU052_03705	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CU052_03720	COG0772	Belongs to the SEDS family
CU052_03735	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CU052_03740	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CU052_03745	COG0768	penicillin binding
CU052_03750	COG3116	cell division
CU052_03770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CU052_03785	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CU052_03790	COG2823	Periplasmic or secreted lipoprotein
CU052_03795	COG2969	positive regulation of protein catabolic process
CU052_03800	COG0625	glutathione transferase activity
CU052_03805	COG2857	Cytochrome c1
CU052_03810	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CU052_03815	COG0723	plastoquinol--plastocyanin reductase activity
CU052_03835	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CU052_03845	COG3105	Protein conserved in bacteria
CU052_03860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CU052_03865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CU052_03870	COG0187	DNA topoisomerase II activity
CU052_03875	COG3150	esterase
CU052_03885	COG3151	Protein conserved in bacteria
CU052_03890	COG0494	nUDIX hydrolase
CU052_03895	COG1538	Outer membrane efflux protein
CU052_03905	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CU052_03915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CU052_03920	COG3025	triphosphatase activity
CU052_03925	COG1392	Phosphate transport regulator
CU052_03930	COG0306	phosphate transporter
CU052_03935	COG4991	sh3 domain protein
CU052_03945	COG3409	Peptidoglycan-binding domain 1 protein
CU052_03945	COG3267	Type II secretory pathway component ExeA
CU052_03960	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CU052_03965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CU052_03975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CU052_03980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CU052_03985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CU052_03990	COG1610	YqeY-like protein
CU052_03995	COG0358	DNA primase activity
CU052_04000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CU052_04030	COG2213	PTS system mannitol-specific
CU052_04030	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_04040	COG3722	fumarate hydratase activity
CU052_04045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CU052_04050	COG5002	protein histidine kinase activity
CU052_04070	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CU052_04075	COG1349	DNA-binding transcription factor activity
CU052_04085	COG0469	pyruvate kinase activity
CU052_04100	COG0440	acetolactate synthase activity
CU052_04105	COG0028	Belongs to the TPP enzyme family
CU052_04110	COG1022	Amp-dependent synthetase and ligase
CU052_04115	COG0583	DNA-binding transcription factor activity
CU052_04125	COG0671	phosphoesterase, PA-phosphatase related
CU052_04140	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CU052_04145	COG0473	3-isopropylmalate dehydrogenase activity
CU052_04165	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CU052_04170	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CU052_04175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CU052_04180	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CU052_04185	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CU052_04205	COG3610	response to peptide
CU052_04210	COG2966	Psort location CytoplasmicMembrane, score
CU052_04215	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CU052_04225	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CU052_04230	COG0142	geranyltranstransferase activity
CU052_04270	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
CU052_04275	COG1178	ABC-type Fe3 transport system permease component
CU052_04280	COG4143	(ABC) transporter
CU052_04285	COG0163	prenyltransferase activity
CU052_04290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CU052_04300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CU052_04310	COG2105	PFAM AIG2 family protein
CU052_04320	COG0729	surface antigen
CU052_04325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CU052_04335	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
CU052_04350	COG1136	(ABC) transporter
CU052_04370	COG0529	Catalyzes the synthesis of activated sulfate
CU052_04375	COG3273	potassium ion transport
CU052_04375	COG0471	metal ion transport
CU052_04390	COG1648	precorrin-2 dehydrogenase activity
CU052_04390	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CU052_04395	COG0737	Belongs to the 5'-nucleotidase family
CU052_04405	COG0513	Belongs to the DEAD box helicase family
CU052_04410	COG2153	protein acetylation
CU052_04425	COG0545	Peptidyl-prolyl cis-trans isomerase
CU052_04435	COG0203	ribosomal protein L17
CU052_04440	COG0202	RNA polymerase activity
CU052_04450	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CU052_04455	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CU052_04465	COG0201	protein transport
CU052_04470	COG0200	Binds to the 23S rRNA
CU052_04475	COG1841	ribosomal large subunit assembly
CU052_04490	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CU052_04540	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CU052_04560	COG0088	Forms part of the polypeptide exit tunnel
CU052_04575	COG0254	rRNA binding
CU052_04585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CU052_04590	COG1609	Transcriptional regulator
CU052_04615	COG2003	Belongs to the UPF0758 family
CU052_04650	COG1575	Belongs to the MenA family. Type 1 subfamily
CU052_04655	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CU052_04665	COG1494	fructose-1,6-bisphosphatase
CU052_04695	COG0149	triose-phosphate isomerase activity
CU052_04720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CU052_04750	COG4584	PFAM Integrase catalytic
CU052_04760	COG1561	YicC-like family, N-terminal region
CU052_04765	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CU052_04775	COG1560	Kdo2-lipid A biosynthetic process
CU052_04785	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CU052_04795	COG0840	transmembrane signaling receptor activity
CU052_04815	COG2194	sulfuric ester hydrolase activity
CU052_04830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CU052_04845	COG0463	Glycosyl transferase, family 2
CU052_04850	COG0859	PFAM glycosyl transferase family 9
CU052_04855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CU052_04860	COG3642	lipopolysaccharide core region biosynthetic process
CU052_04900	COG1519	Transferase
CU052_04905	COG0859	PFAM glycosyl transferase family 9
CU052_04910	COG1560	Kdo2-lipid A biosynthetic process
CU052_04920	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CU052_04960	COG2089	acid synthase
CU052_04985	COG3306	glycosyltransferase involved in LPS biosynthesis
CU052_05030	COG0328	RNA-DNA hybrid ribonuclease activity
CU052_05060	COG0745	RESPONSE REGULATOR receiver
CU052_05085	COG4608	Belongs to the ABC transporter superfamily
CU052_05090	COG0444	Belongs to the ABC transporter superfamily
CU052_05095	COG0747	negative chemotaxis
CU052_05100	COG4239	(ABC) transporter, permease
CU052_05105	COG0601	transmembrane transport
CU052_05130	COG0811	peptide transport
CU052_05135	COG0848	biopolymer transport protein
CU052_05150	COG0194	GDP metabolic process
CU052_05155	COG1758	RNA polymerase activity
CU052_05160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CU052_05165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CU052_05170	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CU052_05180	COG2233	PERMEase
CU052_05185	COG2205	protein histidine kinase activity
CU052_05190	COG0745	RESPONSE REGULATOR receiver
CU052_05195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CU052_05205	COG2183	response to ionizing radiation
CU052_05220	COG1040	competence protein
CU052_05230	COG0494	nUDIX hydrolase
CU052_05235	COG1218	3'(2'),5'-bisphosphate nucleotidase
CU052_05245	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CU052_05250	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
CU052_05255	COG3156	type II secretion system protein K
CU052_05260	COG4795	General secretion pathway protein
CU052_05265	COG2165	general secretion pathway protein
CU052_05270	COG2165	general secretion pathway protein
CU052_05275	COG2165	general secretion pathway protein
CU052_05280	COG1459	type II secretion system
CU052_05285	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CU052_05295	COG3031	protein transport across the cell outer membrane
CU052_05300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CU052_05320	COG0456	acetyltransferase
CU052_05325	COG1490	D-aminoacyl-tRNA deacylase activity
CU052_05355	COG0174	glutamine synthetase
CU052_05365	COG3852	Histidine kinase
CU052_05370	COG2204	response regulator
CU052_05380	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CU052_05385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CU052_05410	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CU052_05420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CU052_05420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CU052_05440	COG0084	hydrolase, TatD family'
CU052_05445	COG0805	protein transport
CU052_05465	COG3165	ubiquinone biosynthetic process from chorismate
CU052_05475	COG1322	Protein conserved in bacteria
CU052_05495	COG2081	HI0933 family
CU052_05505	COG1528	Iron-storage protein
CU052_05515	COG0589	response to stress
CU052_05520	COG0697	spore germination
CU052_05530	COG2801	Transposase and inactivated derivatives
CU052_05540	COG5002	protein histidine kinase activity
CU052_05540	COG5001	Diguanylate cyclase
CU052_05545	COG1522	sequence-specific DNA binding
CU052_05560	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CU052_05570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CU052_05585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CU052_05605	COG0800	Aldolase
CU052_05610	COG2610	gluconate transmembrane transporter activity
CU052_05615	COG3265	gluconokinase activity
CU052_05620	COG0129	dihydroxy-acid dehydratase activity
CU052_05635	COG2076	Multidrug Resistance protein
CU052_05640	COG0583	DNA-binding transcription factor activity
CU052_05645	COG1609	Transcriptional regulator
CU052_05680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU052_05690	COG0747	negative chemotaxis
CU052_05695	COG4172	Belongs to the ABC transporter superfamily
CU052_05745	COG1309	transcriptional regulator
CU052_05750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU052_05755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU052_05765	COG2960	long-chain fatty acid transporting porin activity
CU052_05770	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CU052_05775	COG0583	DNA-binding transcription factor activity
CU052_05830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CU052_05835	COG1739	Uncharacterized protein family UPF0029
CU052_05845	COG0183	Belongs to the thiolase family
CU052_05850	COG0604	alcohol dehydrogenase
CU052_05865	COG0425	Belongs to the sulfur carrier protein TusA family
CU052_05875	COG2119	membrane
CU052_05890	COG0366	Alpha amylase catalytic
CU052_05895	COG3977	Valine--pyruvate aminotransferase
CU052_05900	COG0071	Belongs to the small heat shock protein (HSP20) family
CU052_05905	COG0187	DNA topoisomerase II activity
CU052_05915	COG0592	DNA-directed DNA polymerase activity
CU052_05940	COG1126	abc transporter atp-binding protein
CU052_05955	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CU052_05970	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CU052_05975	COG0445	tRNA wobble uridine modification
CU052_05985	COG1192	Involved in chromosome partitioning
CU052_05990	COG1475	DNA binding
CU052_05995	COG3312	ion transport
CU052_06000	COG0356	it plays a direct role in the translocation of protons across the membrane
CU052_06025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CU052_06035	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CU052_06045	COG0765	amino acid transport
CU052_06055	COG2814	Major facilitator Superfamily
CU052_06060	COG0583	DNA-binding transcription factor activity
CU052_06070	COG0129	dihydroxy-acid dehydratase activity
CU052_06075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CU052_06080	COG3978	acetolactate synthase activity
CU052_06125	COG4974	Belongs to the 'phage' integrase family
CU052_06225	COG2801	Transposase and inactivated derivatives
CU052_06235	COG3706	GGDEF domain
CU052_06245	COG0204	Acyl-transferase
CU052_06250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CU052_06255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CU052_06265	COG3084	Protein conserved in bacteria
CU052_06275	COG4326	sporulation control protein
CU052_06280	COG1272	protein, Hemolysin III
CU052_06290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CU052_06295	COG0569	domain protein
CU052_06300	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CU052_06300	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CU052_06310	COG0242	peptide deformylase activity
CU052_06320	COG0758	DNA mediated transformation
CU052_06330	COG0551	DNA topoisomerase type I activity
CU052_06335	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CU052_06340	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CU052_06355	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CU052_06365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CU052_06415	COG2132	Multicopper oxidase
CU052_06435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CU052_06440	COG2104	thiamine diphosphate biosynthetic process
CU052_06455	COG0006	proline dipeptidase activity
CU052_06455	COG0006	proline dipeptidase activity
CU052_06465	COG2814	Major facilitator Superfamily
CU052_06485	COG3220	belongs to the UPF0276 family
CU052_06495	COG0210	DNA helicase
CU052_06505	COG0405	Gamma-glutamyltransferase
CU052_06510	COG1280	lysine exporter protein (LysE YggA)
CU052_06520	COG2962	Rard protein
CU052_06525	COG0514	ATP-dependent DNA helicase (RecQ)
CU052_06540	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CU052_06555	COG3118	belongs to the thioredoxin family
CU052_06560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CU052_06570	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CU052_06575	COG0633	Ferredoxin
CU052_06615	COG3071	HemY protein
CU052_06620	COG2959	enzyme of heme biosynthesis
CU052_06625	COG1587	Uroporphyrinogen-III synthase
CU052_06635	COG3072	Adenylate cyclase
CU052_06650	COG0019	diaminopimelate decarboxylase activity
CU052_06670	COG1011	Hydrolase
CU052_06695	COG0561	phosphatase activity
CU052_06700	COG2267	carboxylic ester hydrolase activity
CU052_06705	COG1280	lysine exporter protein (LysE YggA)
CU052_06710	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CU052_06715	COG0640	Transcriptional regulator
CU052_06720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CU052_06770	COG2095	MarC family integral membrane protein
CU052_06780	COG0742	ribosomal rna small subunit methyltransferase
CU052_06785	COG0552	protein localization to endoplasmic reticulum
CU052_06785	COG0552	protein localization to endoplasmic reticulum
CU052_06790	COG2884	Cell division ATP-binding protein ftsE
CU052_06795	COG2177	Part of the ABC transporter FtsEX involved in
CU052_06810	COG0705	Rhomboid family
CU052_06815	COG1580	Controls the rotational direction of flagella during chemotaxis
CU052_06820	COG3161	chorismate lyase activity
CU052_06830	COG2937	Belongs to the GPAT DAPAT family
CU052_06850	COG0534	Mate efflux family protein
CU052_06975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CU052_06985	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CU052_07030	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CU052_07035	COG0250	Participates in transcription elongation, termination and antitermination
CU052_07050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CU052_07070	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
CU052_07075	COG2816	NAD+ diphosphatase activity
CU052_07095	COG1573	uracil-dna glycosylase
CU052_07105	COG3068	Protein conserved in bacteria
CU052_07110	COG1253	flavin adenine dinucleotide binding
CU052_07125	COG0151	Belongs to the GarS family
CU052_07140	COG0789	Transcriptional regulator
CU052_07145	COG3710	Transcriptional regulator
CU052_07155	COG0531	amino acid
CU052_07160	COG1982	Orn Lys Arg decarboxylase major
CU052_07195	COG5001	Diguanylate cyclase
CU052_07195	COG3300	MHYT domain
CU052_07200	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CU052_07205	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CU052_07220	COG0439	Biotin carboxylase
CU052_07225	COG0511	ligase activity, forming carbon-carbon bonds
CU052_07230	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CU052_07235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CU052_07250	COG2814	Major facilitator Superfamily
CU052_07255	COG0784	Response regulator, receiver
CU052_07255	COG2198	Histidine kinase
CU052_07255	COG2205	protein histidine kinase activity
CU052_07285	COG2095	MarC family integral membrane protein
CU052_07295	COG4232	protein-disulfide reductase activity
CU052_07300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CU052_07305	COG1027	Aspartate ammonia-lyase
CU052_07315	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CU052_07320	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CU052_07325	COG2205	protein histidine kinase activity
CU052_07330	COG0745	RESPONSE REGULATOR receiver
CU052_07335	COG3678	ATP-independent chaperone mediated protein folding
CU052_07340	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CU052_07350	COG0534	Mate efflux family protein
CU052_07375	COG1509	lysine 2,3-aminomutase activity
CU052_07405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CU052_07410	COG1053	succinate dehydrogenase
CU052_07435	COG4942	peptidase
CU052_07440	COG1045	serine acetyltransferase
CU052_07450	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CU052_07455	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CU052_07460	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CU052_07470	COG0840	transmembrane signaling receptor activity
CU052_07475	COG0471	metal ion transport
CU052_07485	COG1162	GTPase activity
CU052_07555	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CU052_07560	COG0802	atpase or kinase
CU052_07570	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CU052_07585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CU052_07590	COG0330	HflC and HflK could
CU052_07595	COG0330	HflC and HflK could
CU052_07600	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CU052_07605	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CU052_07615	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
CU052_07620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CU052_07620	COG1017	nitric oxide dioxygenase activity
CU052_07635	COG0557	exoribonuclease II activity
CU052_07640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CU052_07645	COG0546	phosphoglycolate phosphatase activity
CU052_07675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CU052_07695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CU052_07700	COG3954	Phosphoribulokinase
CU052_07710	COG0429	hydrolase of the alpha beta-hydrolase fold
CU052_07720	COG0488	(ABC) transporter
CU052_07730	COG2249	NAD(P)H dehydrogenase (quinone) activity
CU052_07745	COG1047	Peptidyl-prolyl cis-trans
CU052_07755	COG1446	asparaginase
CU052_07770	COG0545	Peptidyl-prolyl cis-trans isomerase
CU052_07775	COG2964	Protein conserved in bacteria
CU052_07780	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CU052_07785	COG2923	Belongs to the DsrF TusC family
CU052_07790	COG2168	tRNA wobble position uridine thiolation
CU052_07805	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CU052_07815	COG2906	2 iron, 2 sulfur cluster binding
CU052_07825	COG0281	malic enzyme
CU052_07835	COG0626	cystathionine gamma-synthase activity
CU052_07840	COG0460	homoserine dehydrogenase
CU052_07840	COG0527	aspartate kinase activity
CU052_07845	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CU052_07855	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CU052_07865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CU052_07880	COG0165	Argininosuccinate lyase
CU052_07880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CU052_07895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CU052_07900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CU052_07900	COG0678	peroxiredoxin activity
CU052_07910	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
CU052_07955	COG0338	D12 class N6 adenine-specific DNA methyltransferase
CU052_07960	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CU052_07985	COG0305	Participates in initiation and elongation during chromosome replication
CU052_07990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CU052_08000	COG0432	Pfam Uncharacterised protein family UPF0047
CU052_08015	COG0735	belongs to the Fur family
CU052_08020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CU052_08040	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CU052_08090	COG0646	methionine synthase
CU052_08090	COG1410	methionine synthase
CU052_08095	COG0527	aspartate kinase activity
CU052_08105	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CU052_08115	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CU052_08130	COG0629	single-stranded DNA binding
CU052_08135	COG2200	EAL domain
CU052_08135	COG2199	diguanylate cyclase activity
CU052_08175	COG3267	Type II secretory pathway component ExeA
CU052_08175	COG3409	Peptidoglycan-binding domain 1 protein
CU052_08185	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CU052_08190	COG1459	type II secretion system
CU052_08235	COG1077	Cell shape determining protein MreB Mrl
CU052_08240	COG1792	Involved in formation and maintenance of cell shape
CU052_08245	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CU052_08250	COG0424	maF-like protein
CU052_08255	COG1530	ribonuclease E activity
CU052_08260	COG3164	Protein of unknown function
CU052_08265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CU052_08270	COG0312	modulator of DNA gyrase
CU052_08275	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CU052_08290	COG0564	pseudouridine synthase activity
CU052_08295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CU052_08305	COG0312	modulator of DNA gyrase
CU052_08310	COG2239	Acts as a magnesium transporter
CU052_08315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_08325	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_08330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CU052_08340	COG1137	ATPase activity
CU052_08345	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CU052_08365	COG1127	ABC transporter
CU052_08370	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CU052_08375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CU052_08380	COG2854	intermembrane phospholipid transfer
CU052_08390	COG5007	Belongs to the BolA IbaG family
CU052_08400	COG0204	Acyl-transferase
CU052_08405	COG0251	oxidation-reduction process
CU052_08445	COG0456	acetyltransferase
CU052_08455	COG0525	valine-tRNA ligase activity
CU052_08460	COG2927	DNA polymerase III (CHI subunit)
CU052_08470	COG0795	lipopolysaccharide-transporting ATPase activity
CU052_08475	COG0795	lipopolysaccharide-transporting ATPase activity
CU052_08485	COG1028	Short-chain dehydrogenase reductase Sdr
CU052_08505	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU052_08515	COG1447	Phosphotransferase system cellobiose-specific component IIA
CU052_08520	COG1486	melibiose metabolic process
CU052_08535	COG3437	response regulator, receiver
CU052_08590	COG1012	belongs to the aldehyde dehydrogenase family
CU052_08690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CU052_08695	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CU052_08710	COG0762	integral membrane protein
CU052_08715	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CU052_08720	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CU052_08735	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CU052_08740	COG1678	Uncharacterized ACR, COG1678
CU052_08745	COG0189	ligase activity
CU052_08750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CU052_08755	COG2356	endonuclease I
CU052_08780	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CU052_08800	COG0191	fructose-bisphosphate aldolase activity
CU052_08805	COG0668	transmembrane transport
CU052_08820	COG0583	DNA-binding transcription factor activity
CU052_08830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CU052_08840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CU052_08850	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CU052_08865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CU052_08870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CU052_08890	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CU052_08900	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CU052_08910	COG1595	DNA-templated transcription, initiation
CU052_08925	COG3086	response to oxidative stress
CU052_08935	COG0681	Belongs to the peptidase S26 family
CU052_08945	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CU052_08950	COG1381	Involved in DNA repair and RecF pathway recombination
CU052_08955	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CU052_08980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CU052_08985	COG3956	TIGRFAM MazG family protein
CU052_08995	COG0148	phosphopyruvate hydratase activity
CU052_09005	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CU052_09035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CU052_09050	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CU052_09065	COG0527	aspartate kinase activity
CU052_09130	COG5016	pyruvate
CU052_09130	COG0511	ligase activity, forming carbon-carbon bonds
CU052_09135	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CU052_09150	COG0612	Peptidase, M16
CU052_09170	COG4536	flavin adenine dinucleotide binding
CU052_09175	COG4137	Cytochrome C assembly protein
CU052_09180	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CU052_09205	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CU052_09210	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CU052_09215	COG0237	dephospho-CoA kinase activity
CU052_09225	COG1459	type II secretion system
CU052_09230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CU052_09255	COG2186	Transcriptional regulator
CU052_09260	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CU052_09265	COG0508	dehydrogenase complex catalyzes the overall conversion of
CU052_09270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CU052_09285	COG0288	reversible hydration of carbon dioxide
CU052_09290	COG0659	secondary active sulfate transmembrane transporter activity
CU052_09295	COG1131	(ABC) transporter
CU052_09300	COG0842	Transport permease protein
CU052_09305	COG1560	Kdo2-lipid A biosynthetic process
CU052_09320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CU052_09335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CU052_09340	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CU052_09350	COG1643	Atp-dependent helicase
CU052_09355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CU052_09360	COG1752	Esterase of the alpha-beta hydrolase superfamily
CU052_09365	COG1049	propionate catabolic process, 2-methylcitrate cycle
CU052_09385	COG0004	ammonium transporteR
CU052_09390	COG1840	ABC-type Fe3 transport system, periplasmic component
CU052_09400	COG3842	ATPase activity
CU052_09405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CU052_09420	COG2971	BadF BadG BcrA BcrD
CU052_09430	COG4608	Belongs to the ABC transporter superfamily
CU052_09435	COG0444	Belongs to the ABC transporter superfamily
CU052_09440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU052_09450	COG0747	negative chemotaxis
CU052_09455	COG2205	protein histidine kinase activity
CU052_09455	COG0784	Response regulator, receiver
CU052_09455	COG2198	Histidine kinase
CU052_09455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU052_09470	COG0628	permease
CU052_09480	COG0316	Belongs to the HesB IscA family
CU052_09495	COG0739	heme binding
CU052_09500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CU052_09510	COG2027	D-alanyl-D-alanine carboxypeptidase
CU052_09515	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CU052_09520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CU052_09525	COG1534	Rna-binding protein
CU052_09535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CU052_09540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CU052_09550	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CU052_09570	COG0195	Participates in both transcription termination and antitermination
CU052_09590	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CU052_09610	COG0534	Mate efflux family protein
CU052_09635	COG3153	acetyltransferase
CU052_09655	COG3706	GGDEF domain
CU052_09660	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CU052_09670	COG0084	hydrolase, TatD family'
CU052_09675	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CU052_09685	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CU052_09695	COG0813	purine-nucleoside phosphorylase activity
CU052_09705	COG0560	Phosphoserine phosphatase
CU052_09715	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CU052_09720	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CU052_09725	COG0583	DNA-binding transcription factor activity
CU052_09735	COG1022	Amp-dependent synthetase and ligase
CU052_09740	COG2169	Transcriptional regulator
CU052_09765	COG4964	Belongs to the GSP D family
CU052_09825	COG0583	DNA-binding transcription factor activity
CU052_09830	COG0531	amino acid
CU052_09835	COG2731	YhcH YjgK YiaL family protein
CU052_09840	COG3250	beta-galactosidase activity
CU052_09850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CU052_09860	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU052_09860	COG1263	PTS System
CU052_09870	COG2017	converts alpha-aldose to the beta-anomer
CU052_09885	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CU052_09890	COG0768	penicillin binding
CU052_09900	COG1609	Transcriptional regulator
CU052_09920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CU052_09925	COG1349	DNA-binding transcription factor activity
CU052_09935	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CU052_09945	COG2271	Major facilitator Superfamily
CU052_09950	COG0584	glycerophosphoryl diester phosphodiesterase
CU052_09955	COG2171	N-acyltransferase activity
CU052_09970	COG3141	response to X-ray
CU052_09990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CU052_09995	COG1074	ATP-dependent DNA helicase activity
CU052_10000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CU052_10025	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CU052_10025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CU052_10040	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
CU052_10045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CU052_10050	COG2166	iron-sulfur cluster assembly
CU052_10055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CU052_10060	COG0693	protein deglycase activity
CU052_10065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CU052_10070	COG3248	Nucleoside-binding outer membrane protein
CU052_10090	COG1595	DNA-templated transcription, initiation
CU052_10120	COG0271	Belongs to the BolA IbaG family
CU052_10145	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
CU052_10155	COG1477	protein flavinylation
CU052_10165	COG0745	RESPONSE REGULATOR receiver
CU052_10165	COG3706	GGDEF domain
CU052_10170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CU052_10175	COG0514	ATP-dependent DNA helicase (RecQ)
CU052_10180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CU052_10195	COG0733	neurotransmitter:sodium symporter activity
CU052_10220	COG1720	tRNA m6t6A37 methyltransferase activity
CU052_10235	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
CU052_10260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CU052_10280	COG2801	Transposase and inactivated derivatives
CU052_10305	COG3098	single-species biofilm formation
CU052_10310	COG0564	pseudouridine synthase activity
CU052_10325	COG0024	Methionine aminopeptidase
CU052_10350	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CU052_10355	COG0575	Belongs to the CDS family
CU052_10365	COG0750	zinc metalloprotease
CU052_10375	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
CU052_10380	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CU052_10405	COG0587	DNA-directed DNA polymerase activity
CU052_10425	COG0347	Belongs to the P(II) protein family
CU052_10440	COG1388	LysM domain
CU052_10440	COG0741	lytic transglycosylase activity
CU052_10450	COG2226	methyltransferase
CU052_10460	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CU052_10485	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CU052_10490	COG0121	glutamine amidotransferase
CU052_10495	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CU052_10505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CU052_10510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CU052_10515	COG2233	PERMEase
CU052_10535	COG1393	Belongs to the ArsC family
CU052_10540	COG4783	chaperone-mediated protein folding
CU052_10555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CU052_10560	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CU052_10570	COG0732	type I restriction modification DNA specificity domain
CU052_10575	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CU052_10635	COG4615	Cyclic peptide transporter
CU052_10640	COG4166	transmembrane transport
CU052_10645	COG4174	ABC transporter (Permease)
CU052_10650	COG4239	(ABC) transporter, permease
CU052_10655	COG4172	Belongs to the ABC transporter superfamily
CU052_10675	COG4774	siderophore transport
CU052_10680	COG3251	PFAM MbtH domain protein
CU052_10730	COG0612	Peptidase, M16
CU052_10735	COG4178	(ABC) transporter
CU052_10740	COG4771	TonB-dependent receptor
CU052_10750	COG0811	peptide transport
CU052_10755	COG0811	peptide transport
CU052_10760	COG0848	biopolymer transport protein
CU052_10805	COG2801	Transposase and inactivated derivatives
CU052_10820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CU052_10860	COG2716	regulation of RNA biosynthetic process
CU052_10865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CU052_10890	COG1393	Belongs to the ArsC family
CU052_10915	COG2837	iron assimilation
CU052_10920	COG2169	Transcriptional regulator
CU052_10925	COG1486	melibiose metabolic process
CU052_10930	COG2211	Major facilitator Superfamily
CU052_10935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CU052_10945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CU052_10955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CU052_10960	COG1334	flagellar protein FlaG
CU052_10965	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CU052_10975	COG1516	flagellar protein fliS
CU052_10985	COG4191	Histidine kinase
CU052_10990	COG2204	response regulator
CU052_10995	COG1677	Flagellar hook-basal body complex protein FliE
CU052_11005	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CU052_11060	COG1987	bacterial-type flagellum assembly
CU052_11065	COG1684	flagellar biosynthetic protein fliR
CU052_11085	COG0455	bacterial-type flagellum organization
CU052_11100	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CU052_11105	COG2198	Histidine kinase
CU052_11105	COG0643	Histidine kinase
CU052_11110	COG2201	protein-glutamate methylesterase activity
CU052_11115	COG1192	Involved in chromosome partitioning
CU052_11125	COG0835	chemotaxis
CU052_11135	COG4133	protoheme IX ABC transporter activity
CU052_11140	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CU052_11145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CU052_11160	COG1138	Cytochrome C-type biogenesis protein
CU052_11165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CU052_11175	COG4235	cytochrome complex assembly
CU052_11175	COG3088	subunit of a heme lyase
CU052_11180	COG2853	Lipoprotein
CU052_11205	COG0183	Belongs to the thiolase family
CU052_11220	COG2062	phosphohistidine phosphatase, SixA
CU052_11230	COG2890	protein-(glutamine-N5) methyltransferase activity
CU052_11240	COG2860	membrane
CU052_11245	COG3101	peptidyl-lysine hydroxylation
CU052_11265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CU052_11275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CU052_11280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CU052_11305	COG0285	dihydrofolate synthase activity
CU052_11310	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
CU052_11315	COG1286	toxin biosynthetic process
CU052_11320	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CU052_11325	COG0583	DNA-binding transcription factor activity
CU052_11330	COG0745	RESPONSE REGULATOR receiver
CU052_11340	COG2832	Protein of unknown function (DUF454)
CU052_11350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CU052_11360	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CU052_11365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CU052_11370	COG0814	amino acid
CU052_11375	COG0251	oxidation-reduction process
CU052_11385	COG2964	Protein conserved in bacteria
CU052_11455	COG2801	Transposase and inactivated derivatives
CU052_11480	COG4104	PAAR repeat-containing protein
CU052_11490	COG1074	ATP-dependent DNA helicase activity
CU052_11500	COG2261	transglycosylase associated protein
CU052_11505	COG0668	transmembrane transport
CU052_11510	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CU052_11515	COG0346	lactoylglutathione lyase activity
CU052_11525	COG1785	Belongs to the alkaline phosphatase family
CU052_11545	COG2226	methyltransferase
CU052_11565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CU052_11570	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CU052_11580	COG3139	Protein of unknown function (DUF1315)
CU052_11585	COG0252	asparaginase activity
CU052_11590	COG0616	signal peptide processing
CU052_11595	COG1902	pentaerythritol trinitrate reductase activity
CU052_11595	COG0446	pyridine nucleotide-disulphide oxidoreductase
CU052_11600	COG0778	Nitroreductase
CU052_11605	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CU052_11620	COG0123	including yeast histone deacetylase and acetoin utilization protein
CU052_11630	COG3083	sulfuric ester hydrolase activity
CU052_11655	COG1757	Na H antiporter
CU052_11660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CU052_11665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CU052_11670	COG2095	MarC family integral membrane protein
CU052_11675	COG1454	alcohol dehydrogenase
CU052_11675	COG1012	belongs to the aldehyde dehydrogenase family
CU052_11695	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CU052_11705	COG2056	Na+-H+ antiporter family
CU052_11715	COG2885	chlorophyll binding
CU052_11725	COG0346	lactoylglutathione lyase activity
CU052_11730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CU052_11735	COG4660	Part of a membrane complex involved in electron transport
CU052_11740	COG4659	FMN binding
CU052_11745	COG4658	electron transport chain
CU052_11750	COG4656	Part of a membrane complex involved in electron transport
CU052_11760	COG4657	Part of a membrane complex involved in electron transport
CU052_11765	COG1882	Formate acetyltransferase
CU052_11775	COG0556	nucleotide-excision repair
CU052_11790	COG0391	Required for morphogenesis under gluconeogenic growth conditions
CU052_11795	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CU052_11800	COG0521	Mo-molybdopterin cofactor biosynthetic process
CU052_11810	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CU052_11815	COG0314	molybdopterin synthase activity
CU052_11835	COG0601	transmembrane transport
CU052_11840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU052_11845	COG0444	Belongs to the ABC transporter superfamily
CU052_11855	COG0435	Glutathione S-transferase
CU052_11860	COG3174	membrane
CU052_11865	COG0280	phosphate acetyltransferase
CU052_11865	COG0857	belongs to the CobB CobQ family
CU052_11890	COG4120	Belongs to the binding-protein-dependent transport system permease family
CU052_11895	COG1122	ATPase activity
CU052_11915	COG3706	GGDEF domain
CU052_11920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CU052_11925	COG0653	protein targeting
CU052_11930	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CU052_11940	COG2186	Transcriptional regulator
CU052_11970	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CU052_11975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CU052_11980	COG0659	secondary active sulfate transmembrane transporter activity
CU052_11990	COG1530	ribonuclease E activity
CU052_11995	COG0564	pseudouridine synthase activity
CU052_12000	COG0424	maF-like protein
CU052_12005	COG1399	metal-binding, possibly nucleic acid-binding protein
CU052_12020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CU052_12050	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CU052_12065	COG0084	hydrolase, TatD family'
CU052_12070	COG1263	PTS System
CU052_12070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU052_12085	COG0733	neurotransmitter:sodium symporter activity
CU052_12100	COG4667	esterase of the alpha-beta hydrolase superfamily
CU052_12110	COG1940	carbohydrate kinase activity
CU052_12115	COG0784	Response regulator, receiver
CU052_12115	COG0835	chemotaxis
CU052_12145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU052_12155	COG1028	Short-chain dehydrogenase reductase Sdr
CU052_12160	COG0616	signal peptide processing
CU052_12170	COG0539	negative regulation of cytoplasmic translation
CU052_12180	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
CU052_12185	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CU052_12195	COG4166	transmembrane transport
CU052_12250	COG3009	Protein conserved in bacteria
CU052_12255	COG3008	intermembrane lipid transfer
CU052_12255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CU052_12260	COG2995	paraquat-inducible protein a
CU052_12275	COG4232	protein-disulfide reductase activity
CU052_12280	COG3118	belongs to the thioredoxin family
CU052_12310	COG3153	acetyltransferase
CU052_12335	COG0577	efflux transmembrane transporter activity
CU052_12345	COG1136	(ABC) transporter
CU052_12345	COG0577	efflux transmembrane transporter activity
CU052_12375	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CU052_12390	COG1846	Transcriptional regulator
CU052_12425	COG5002	protein histidine kinase activity
CU052_12425	COG3850	Histidine kinase
CU052_12430	COG0745	RESPONSE REGULATOR receiver
CU052_12435	COG0463	Glycosyl transferase, family 2
CU052_12440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CU052_12455	COG2801	Transposase and inactivated derivatives
CU052_12465	COG2964	Protein conserved in bacteria
CU052_12480	COG0446	pyridine nucleotide-disulphide oxidoreductase
CU052_12520	COG1032	radical SAM domain protein
CU052_12525	COG5001	Diguanylate cyclase
CU052_12525	COG1716	ATPase activity
CU052_12540	COG0583	DNA-binding transcription factor activity
CU052_12555	COG2350	Protein conserved in bacteria
CU052_12560	COG1607	acyl-coa hydrolase
CU052_12585	COG1301	dicarboxylic acid transport
CU052_12590	COG0159	tryptophan synthase activity
CU052_12600	COG0134	indole-3-glycerol-phosphate synthase activity
CU052_12600	COG0135	phosphoribosylanthranilate isomerase activity
CU052_12610	COG0512	Glutamine amidotransferase of anthranilate synthase
CU052_12615	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CU052_12625	COG0613	PHP domain protein
CU052_12630	COG0009	L-threonylcarbamoyladenylate synthase
CU052_12640	COG1187	pseudouridine synthase activity
CU052_12660	COG0417	DNA replication proofreading
CU052_12665	COG2197	response regulator
CU052_12670	COG0322	excinuclease ABC activity
CU052_12715	COG0019	diaminopimelate decarboxylase activity
CU052_12740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CU052_12745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CU052_12755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CU052_12775	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
CU052_12785	COG0437	4 iron, 4 sulfur cluster binding
CU052_12790	COG3301	Polysulphide reductase, NrfD
CU052_12795	COG1138	Cytochrome C-type biogenesis protein
CU052_12805	COG4235	cytochrome complex assembly
CU052_12805	COG3088	subunit of a heme lyase
CU052_12815	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CU052_12840	COG2989	Protein conserved in bacteria
CU052_12845	COG3108	Peptidase M15
CU052_12850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CU052_12865	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CU052_12890	COG1846	Transcriptional regulator
CU052_12895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CU052_12900	COG0840	transmembrane signaling receptor activity
CU052_12920	COG1448	Aminotransferase
CU052_12925	COG3437	response regulator, receiver
CU052_12925	COG2770	Histidine kinase
CU052_12960	COG0017	Asparaginyl-tRNA synthetase
CU052_12965	COG0840	transmembrane signaling receptor activity
CU052_12970	COG0720	synthase
CU052_12975	COG2197	response regulator
CU052_12985	COG3300	MHYT domain
CU052_12985	COG5001	Diguanylate cyclase
CU052_12990	COG1760	l-serine dehydratase
CU052_12995	COG0814	amino acid
CU052_13010	COG0784	Response regulator, receiver
CU052_13010	COG2205	protein histidine kinase activity
CU052_13015	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CU052_13030	COG3106	COG3106 Predicted ATPase
CU052_13045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CU052_13185	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CU052_13220	COG0277	FAD linked oxidase domain protein
CU052_13220	COG0247	lactate metabolic process
CU052_13235	COG2986	histidine ammonia-lyase
CU052_13245	COG0010	Belongs to the arginase family
CU052_13255	COG2188	Transcriptional regulator
CU052_13280	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CU052_13290	COG0251	oxidation-reduction process
CU052_13445	COG1783	phage Terminase large subunit
CU052_13450	COG3567	Phage-associated protein, HI1409 family
CU052_13600	COG3706	GGDEF domain
CU052_13600	COG0745	RESPONSE REGULATOR receiver
CU052_13610	COG0072	phenylalanine-tRNA ligase activity
CU052_13610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CU052_13675	COG1346	cytolysis
CU052_13685	COG2925	Exonuclease
CU052_13690	COG0662	Cupin 2, conserved barrel domain protein
CU052_13695	COG1280	lysine exporter protein (LysE YggA)
CU052_13700	COG1794	racemase activity, acting on amino acids and derivatives
CU052_13725	COG0702	epimerase
CU052_13730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CU052_13740	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CU052_13750	COG2062	phosphohistidine phosphatase, SixA
CU052_13765	COG4139	cobalamin transport
CU052_13825	COG0583	DNA-binding transcription factor activity
CU052_13855	COG1451	nucleotide metabolic process
CU052_13865	COG0745	RESPONSE REGULATOR receiver
CU052_13865	COG3706	GGDEF domain
CU052_13885	COG3938	Belongs to the proline racemase family
CU052_13890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CU052_13900	COG2423	ornithine cyclodeaminase activity
CU052_13905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CU052_13910	COG3842	ATPase activity
CU052_13915	COG1176	ABC-type spermidine putrescine transport system, permease component I
CU052_13920	COG1177	transmembrane transport
CU052_13925	COG0813	purine-nucleoside phosphorylase activity
CU052_13945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU052_13950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU052_13960	COG0745	RESPONSE REGULATOR receiver
CU052_14000	COG0444	Belongs to the ABC transporter superfamily
CU052_14005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CU052_14010	COG0601	transmembrane transport
CU052_14020	COG2195	Cleaves the N-terminal amino acid of tripeptides
CU052_14035	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
CU052_14045	COG0625	glutathione transferase activity
CU052_14100	COG1051	belongs to the nudix hydrolase family
CU052_14140	COG4565	transcriptional regulatory protein
CU052_14150	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
CU052_14155	COG5016	pyruvate
CU052_14155	COG0511	ligase activity, forming carbon-carbon bonds
CU052_14160	COG3630	sodium ion export across plasma membrane
CU052_14170	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
CU052_14175	COG3052	prosthetic group binding
CU052_14180	COG2301	Belongs to the HpcH HpaI aldolase family
CU052_14185	COG3051	citrate lyase alpha subunit
CU052_14190	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
CU052_14195	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CU052_14225	COG3284	Transcriptional regulator
CU052_14230	COG1012	belongs to the aldehyde dehydrogenase family
CU052_14235	COG1115	amino acid carrier protein
CU052_14270	COG1368	sulfuric ester hydrolase activity
CU052_14295	COG1404	Belongs to the peptidase S8 family
CU052_14300	COG0583	DNA-binding transcription factor activity
CU052_14320	COG2186	Transcriptional regulator
CU052_14360	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CU052_14380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CU052_14385	COG1999	signal sequence binding
CU052_14400	COG3005	denitrification pathway
CU052_14420	COG0583	DNA-binding transcription factor activity
CU052_14450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU052_14465	COG3290	protein histidine kinase activity
CU052_14470	COG4565	transcriptional regulatory protein
CU052_14475	COG4774	siderophore transport
CU052_14480	COG4977	sequence-specific DNA binding
CU052_14485	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CU052_14490	COG0363	glucosamine-6-phosphate deaminase activity
CU052_14495	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CU052_14530	COG5492	domain, Protein
CU052_14530	COG4932	domain protein
CU052_14535	COG1360	Flagellar Motor Protein
CU052_14575	COG2207	Transcriptional regulator
CU052_14600	COG4964	Belongs to the GSP D family
CU052_14675	COG1254	Belongs to the acylphosphatase family
CU052_14680	COG2920	part of a sulfur-relay system
CU052_14685	COG0670	Belongs to the BI1 family
CU052_14690	COG1126	abc transporter atp-binding protein
CU052_14695	COG0765	amino acid transport
CU052_14700	COG4597	amino acid ABC transporter
CU052_14705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU052_14725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CU052_14755	COG3008	intermembrane lipid transfer
CU052_14760	COG2995	paraquat-inducible protein a
CU052_14765	COG1132	(ABC) transporter
CU052_14770	COG1956	GAF domain-containing protein
CU052_14775	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
CU052_14790	COG0308	aminopeptidase N
CU052_14800	COG2902	Dehydrogenase
CU052_14845	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CU052_14850	COG1067	ATP-dependent peptidase activity
CU052_14875	COG2801	Transposase and inactivated derivatives
CU052_14880	COG2801	Transposase and inactivated derivatives
CU052_14900	COG3278	Belongs to the heme-copper respiratory oxidase family
CU052_14915	COG2010	Cytochrome c
CU052_14925	COG2217	Heavy metal translocating P-type atpase
CU052_14940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CU052_14945	COG0589	response to stress
CU052_14960	COG2992	FlgJ-related protein
CU052_14970	COG3842	ATPase activity
CU052_14975	COG1176	ABC-type spermidine putrescine transport system, permease component I
CU052_14980	COG1177	transmembrane transport
CU052_14985	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CU052_14990	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
CU052_14995	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CU052_15015	COG0437	4 iron, 4 sulfur cluster binding
CU052_15020	COG0243	molybdopterin cofactor binding
CU052_15020	COG3383	formate dehydrogenase (NAD+) activity
CU052_15030	COG3381	protein complex oligomerization
CU052_15050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CU052_15055	COG0488	(ABC) transporter
CU052_15075	COG4191	Histidine kinase
CU052_15090	COG3842	ATPase activity
CU052_15100	COG0303	'Molybdopterin
CU052_15110	COG1940	carbohydrate kinase activity
CU052_15140	COG2801	Transposase and inactivated derivatives
CU052_15165	COG0840	transmembrane signaling receptor activity
CU052_15170	COG0791	NLP P60 protein
CU052_15180	COG3706	GGDEF domain
CU052_15185	COG2201	protein-glutamate methylesterase activity
CU052_15200	COG0307	riboflavin synthase, alpha
CU052_15205	COG0534	Mate efflux family protein
CU052_15215	COG1793	dna ligase
CU052_15245	COG2204	response regulator
CU052_15285	COG0297	glycogen (starch) synthase activity
CU052_15295	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CU052_15305	COG3064	Membrane
CU052_15335	COG2199	diguanylate cyclase activity
CU052_15335	COG2203	Gaf domain
CU052_15345	COG0602	queuosine metabolic process
CU052_15350	COG0561	phosphatase activity
CU052_15375	COG2828	Protein conserved in bacteria
CU052_15385	COG0372	Belongs to the citrate synthase family
CU052_15390	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CU052_15405	COG3501	Rhs element vgr protein
CU052_15500	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CU052_15510	COG0456	acetyltransferase
CU052_15535	COG0730	response to heat
CU052_15550	COG2801	Transposase and inactivated derivatives
CU052_15570	COG1280	lysine exporter protein (LysE YggA)
CU052_15605	COG2197	response regulator
CU052_15610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CU052_15620	COG1846	Transcriptional regulator
CU052_15635	COG1560	Kdo2-lipid A biosynthetic process
CU052_15640	COG0583	DNA-binding transcription factor activity
CU052_15645	COG1280	lysine exporter protein (LysE YggA)
CU052_15650	COG0531	amino acid
CU052_15675	COG3063	Type IV pilus biogenesis stability protein PilW
CU052_15700	COG1643	Atp-dependent helicase
CU052_15705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CU052_15720	COG3302	dmso reductase anchor subunit
CU052_15725	COG0437	4 iron, 4 sulfur cluster binding
CU052_15730	COG0243	molybdopterin cofactor binding
CU052_15760	COG3706	GGDEF domain
CU052_15770	COG0443	Heat shock 70 kDa protein
CU052_15775	COG0443	Heat shock 70 kDa protein
CU052_15800	COG0583	DNA-binding transcription factor activity
CU052_15815	COG1132	(ABC) transporter
CU052_15820	COG1132	(ABC) transporter
CU052_15835	COG4774	siderophore transport
CU052_15840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU052_15845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CU052_15850	COG1120	ATPase activity
CU052_15865	COG0814	amino acid
CU052_15870	COG1454	alcohol dehydrogenase
CU052_15880	COG3706	GGDEF domain
CU052_15890	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CU052_15900	COG0861	Integral membrane protein TerC family
CU052_15910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CU052_15915	COG1328	CTP reductase activity
CU052_15920	COG1280	lysine exporter protein (LysE YggA)
CU052_15930	COG5001	Diguanylate cyclase
CU052_15930	COG3300	MHYT domain
CU052_15940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU052_15940	COG4191	Histidine kinase
CU052_15945	COG0471	metal ion transport
CU052_15990	COG1643	Atp-dependent helicase
CU052_16000	COG2949	membrane
CU052_16005	COG0471	metal ion transport
CU052_16010	COG3706	GGDEF domain
CU052_16030	COG0492	ferredoxin-NADP+ reductase activity
CU052_16035	COG4988	ABC transporter
CU052_16040	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
CU052_16050	COG2610	gluconate transmembrane transporter activity
CU052_16055	COG0583	DNA-binding transcription factor activity
CU052_16075	COG5001	Diguanylate cyclase
CU052_16075	COG5002	protein histidine kinase activity
CU052_16075	COG3447	MASE1 domain protein
CU052_16085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CU052_16095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU052_16095	COG4191	Histidine kinase
CU052_16110	COG3070	regulator of competence-specific genes
CU052_16125	COG2431	L-lysine efflux transmembrane transporter activity
CU052_16135	COG0076	glutamate decarboxylase activity
CU052_16140	COG1737	Transcriptional regulator
CU052_16150	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CU052_16160	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CU052_16190	COG4181	ATPase activity
CU052_16195	COG0534	Mate efflux family protein
CU052_16200	COG0702	epimerase
CU052_16205	COG1609	Transcriptional regulator
CU052_16215	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CU052_16225	COG2814	Major facilitator Superfamily
CU052_16230	COG1187	pseudouridine synthase activity
CU052_16235	COG1061	Type III restriction enzyme res subunit
CU052_16245	COG0745	RESPONSE REGULATOR receiver
CU052_16250	COG2205	protein histidine kinase activity
CU052_16295	COG3313	Fe-S protein
CU052_16305	COG0659	secondary active sulfate transmembrane transporter activity
CU052_16340	COG0398	Pfam SNARE associated Golgi protein
CU052_16345	COG4134	Bacterial extracellular solute-binding protein
CU052_16350	COG4135	transport system, permease component
CU052_16355	COG4136	ATPase activity
CU052_16360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CU052_16365	COG3604	Transcriptional regulator
CU052_16370	COG1151	hydroxylamine reductase activity
CU052_16375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CU052_16385	COG0564	pseudouridine synthase activity
CU052_16395	COG0733	neurotransmitter:sodium symporter activity
CU052_16405	COG0626	cystathionine gamma-synthase activity
CU052_16410	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CU052_16420	COG2818	Glycosylase
CU052_16450	COG1842	Phage shock protein A
CU052_16455	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CU052_16465	COG4168	peptide transport system, permease
CU052_16470	COG4171	peptide transport system, permease
CU052_16480	COG4172	Belongs to the ABC transporter superfamily
CU052_16490	COG1227	inorganic diphosphatase activity
CU052_16495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CU052_16500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CU052_16505	COG1121	(ABC) transporter
CU052_16520	COG0243	molybdopterin cofactor binding
CU052_16525	COG3005	denitrification pathway
CU052_16530	COG4459	periplasmic nitrate reductase
CU052_16535	COG0390	transport system, permease component
CU052_16540	COG2116	formate transmembrane transporter activity
CU052_16570	COG1435	thymidine kinase activity
CU052_16575	COG0215	cysteine-tRNA ligase activity
CU052_16580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CU052_16585	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CU052_16590	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CU052_16595	COG3012	SEC-C Motif Domain Protein
CU052_16600	COG0140	phosphoribosyl-ATP diphosphatase activity
CU052_16600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CU052_16605	COG0107	imidazoleglycerol-phosphate synthase activity
CU052_16610	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CU052_16615	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CU052_16620	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CU052_16620	COG0131	Imidazoleglycerol-phosphate dehydratase
CU052_16625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CU052_16630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CU052_16640	COG1757	Na H antiporter
CU052_16650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU052_16660	COG0482	sulfurtransferase activity
CU052_16670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CU052_16680	COG2268	Band 7 protein
CU052_16690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CU052_16705	COG0300	oxidoreductase activity
CU052_16745	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
CU052_16750	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CU052_16770	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CU052_16780	COG1674	ftsk spoiiie
CU052_16790	COG0686	Belongs to the AlaDH PNT family
CU052_16965	COG2801	Transposase and inactivated derivatives
CU052_16980	COG4934	collagen metabolic process
CU052_16990	COG2963	transposase activity
CU052_17010	COG4584	PFAM Integrase catalytic
CU052_17030	COG0457	Tetratricopeptide repeat
CU052_17095	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CU052_17100	COG4790	Type iii secretion
CU052_17105	COG4794	Type iii secretion
CU052_17110	COG4791	protein targeting
CU052_17115	COG4792	protein secretion
CU052_17160	COG4669	(LipO)protein
CU052_17245	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CU052_17255	COG2801	Transposase and inactivated derivatives
CU052_17265	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CU052_17285	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CU052_17335	COG2003	Belongs to the UPF0758 family
CU052_17380	COG0582	viral genome integration into host DNA
CU052_17395	COG5002	protein histidine kinase activity
CU052_17395	COG0784	Response regulator, receiver
CU052_17405	COG0754	glutathionylspermidine amidase activity
CU052_17415	COG3766	membrane
CU052_17435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CU052_17440	COG0371	Dehydrogenase
CU052_17445	COG2207	Transcriptional regulator
CU052_17450	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU052_17455	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CU052_17460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CU052_17465	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CU052_17475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU052_17485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CU052_17485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_17485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_17490	COG0673	inositol 2-dehydrogenase activity
CU052_17505	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
CU052_17510	COG2885	chlorophyll binding
CU052_17515	COG0823	Involved in the tonB-independent uptake of proteins
CU052_17530	COG0811	peptide transport
CU052_17535	COG0824	Thioesterase
CU052_17545	COG4890	Cyd operon protein YbgT
CU052_17550	COG1294	oxidase, subunit
CU052_17555	COG1271	oxidase subunit
CU052_17565	COG0632	four-way junction helicase activity
CU052_17570	COG0840	transmembrane signaling receptor activity
CU052_17585	COG1801	Protein of unknown function DUF72
CU052_17605	COG4067	protein conserved in archaea
CU052_17605	COG0189	ligase activity
CU052_17625	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
CU052_17630	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
CU052_17640	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CU052_17645	COG1434	Gram-negative-bacterium-type cell wall biogenesis
CU052_17650	COG0745	RESPONSE REGULATOR receiver
CU052_17665	COG3070	regulator of competence-specific genes
CU052_17685	COG0297	glycogen (starch) synthase activity
CU052_17690	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CU052_17695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CU052_17725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CU052_17730	COG0542	response to heat
CU052_17740	COG1278	Cold shock
CU052_17750	COG1187	pseudouridine synthase activity
CU052_17755	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CU052_17765	COG1199	ATP-dependent helicase activity
CU052_17770	COG0730	response to heat
CU052_17785	COG0840	transmembrane signaling receptor activity
CU052_17790	COG0708	Exodeoxyribonuclease III
CU052_17800	COG4215	(ABC) transporter
CU052_17830	COG1882	Formate acetyltransferase
CU052_17840	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CU052_17860	COG2766	serine protein kinase
CU052_17865	COG2718	Belongs to the UPF0229 family
CU052_17875	COG3537	Alpha-1,2-mannosidase
CU052_17885	COG3537	Alpha-1,2-mannosidase
CU052_17890	COG3537	Alpha-1,2-mannosidase
CU052_17895	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU052_17910	COG0561	phosphatase activity
CU052_17920	COG1454	alcohol dehydrogenase
CU052_17925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CU052_17930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CU052_17935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CU052_17940	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CU052_17945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CU052_17950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU052_17950	COG1263	PTS System
CU052_17960	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CU052_17960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CU052_17965	COG0346	lactoylglutathione lyase activity
CU052_17970	COG1349	DNA-binding transcription factor activity
CU052_17975	COG1609	Transcriptional regulator
CU052_17980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU052_17980	COG1263	PTS System
CU052_17985	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CU052_18010	COG0753	catalase activity
CU052_18025	COG1335	isochorismatase
CU052_18050	COG3136	membrane protein required for alginate biosynthesis
CU052_18090	COG0589	response to stress
CU052_18095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CU052_18110	COG4175	Glycine betaine
CU052_18110	COG3448	diguanylate cyclase activity
CU052_18115	COG4176	ABC-type proline glycine betaine transport system permease component
CU052_18125	COG1342	Belongs to the UPF0251 family
CU052_18145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CU052_18155	COG4948	Mandelate Racemase Muconate Lactonizing
CU052_18170	COG0668	transmembrane transport
CU052_18180	COG1304	FMN binding
CU052_18185	COG1620	l-lactate permease
CU052_18190	COG0583	DNA-binding transcription factor activity
CU052_18210	COG4172	Belongs to the ABC transporter superfamily
CU052_18220	COG1067	ATP-dependent peptidase activity
CU052_18250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CU052_18255	COG0437	4 iron, 4 sulfur cluster binding
CU052_18260	COG0348	domain, Protein
CU052_18280	COG1122	ATPase activity
CU052_18290	COG1566	PFAM secretion protein HlyD family protein
CU052_18305	COG3706	GGDEF domain
CU052_18320	COG0813	purine-nucleoside phosphorylase activity
CU052_18330	COG3272	Protein of unknown function (DUF1722)
CU052_18335	COG0789	Transcriptional regulator
CU052_18340	COG0415	Belongs to the DNA photolyase family
CU052_18345	COG1376	ErfK ybiS ycfS ynhG family protein
CU052_18345	COG1388	LysM domain
CU052_18355	COG0513	Belongs to the DEAD box helicase family
CU052_18365	COG0840	transmembrane signaling receptor activity
CU052_18370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CU052_18375	COG0573	inorganic phosphate transmembrane transporter activity
CU052_18380	COG0581	inorganic phosphate transmembrane transporter activity
CU052_18385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CU052_18400	COG2304	oxidoreductase activity
CU052_18420	COG0714	Associated with various cellular activities
CU052_18425	COG0840	transmembrane signaling receptor activity
CU052_18460	COG0110	maltose O-acetyltransferase activity
CU052_18470	COG4191	Histidine kinase
CU052_18480	COG2801	Transposase and inactivated derivatives
CU052_18490	COG0573	inorganic phosphate transmembrane transporter activity
CU052_18500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CU052_18505	COG1028	Short-chain dehydrogenase reductase Sdr
CU052_18520	COG3344	reverse transcriptase
CU052_18555	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CU052_18560	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CU052_18570	COG1252	NADH dehydrogenase
CU052_18595	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU052_18615	COG3383	formate dehydrogenase (NAD+) activity
CU052_18640	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
CU052_18650	COG4145	pantothenate transmembrane transporter activity
CU052_18655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU052_18660	COG0800	Aldolase
CU052_18675	COG0251	oxidation-reduction process
CU052_18680	COG0842	Transport permease protein
CU052_18685	COG1131	(ABC) transporter
CU052_18695	COG0840	transmembrane signaling receptor activity
CU052_18700	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CU052_18705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU052_18715	COG0848	biopolymer transport protein
CU052_18720	COG0811	peptide transport
CU052_18725	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CU052_18735	COG3721	Heme iron utilization protein
CU052_18740	COG0748	coenzyme F420 binding
CU052_18750	COG0835	chemotaxis
CU052_18750	COG0784	Response regulator, receiver
CU052_18755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CU052_18770	COG0366	Alpha amylase catalytic
CU052_18825	COG0583	DNA-binding transcription factor activity
CU052_18840	COG2249	NAD(P)H dehydrogenase (quinone) activity
CU052_18855	COG1881	PFAM PEBP family protein
CU052_18870	COG0798	PFAM Bile acid sodium symporter
CU052_18885	COG1733	regulation of RNA biosynthetic process
CU052_18895	COG0747	negative chemotaxis
CU052_18900	COG1482	cell wall glycoprotein biosynthetic process
CU052_18905	COG0383	alpha-mannosidase activity
CU052_18910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_18910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU052_18910	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU052_18915	COG2188	Transcriptional regulator
CU052_18920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_18925	COG2213	PTS system mannitol-specific
CU052_18930	COG1063	alcohol dehydrogenase
CU052_18940	COG1072	(Pantothenic acid kinase))
CU052_18945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CU052_18965	COG0814	amino acid
CU052_19005	COG0739	heme binding
CU052_19010	COG5001	Diguanylate cyclase
CU052_19015	COG0583	DNA-binding transcription factor activity
CU052_19020	COG2814	Major facilitator Superfamily
CU052_19040	COG0697	spore germination
CU052_19055	COG0179	Fumarylacetoacetate (FAA) hydrolase
CU052_19075	COG1280	lysine exporter protein (LysE YggA)
CU052_19085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CU052_19100	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CU052_19105	COG1845	cytochrome c oxidase, subunit III
CU052_19125	COG1612	heme a metabolic process
CU052_19140	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CU052_19145	COG2814	Major facilitator Superfamily
CU052_19155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CU052_19185	COG2897	thiosulfate sulfurtransferase activity
CU052_19205	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CU052_19215	COG2801	Transposase and inactivated derivatives
CU052_19230	COG1914	H( )-stimulated, divalent metal cation uptake system
CU052_19255	COG4989	oxidoreductase activity
CU052_19270	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CU052_19270	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CU052_19285	COG1073	alpha beta
CU052_19290	COG0583	DNA-binding transcription factor activity
CU052_19310	COG4964	Belongs to the GSP D family
CU052_19320	COG0455	bacterial-type flagellum organization
CU052_19360	COG2885	chlorophyll binding
CU052_19395	COG2801	Transposase and inactivated derivatives
CU052_19420	COG3706	GGDEF domain
CU052_19455	COG4176	ABC-type proline glycine betaine transport system permease component
CU052_19460	COG4175	Glycine betaine
CU052_19460	COG0517	IMP dehydrogenase activity
CU052_19475	COG0330	HflC and HflK could
CU052_19505	COG2205	protein histidine kinase activity
CU052_19505	COG0784	Response regulator, receiver
CU052_19545	COG0586	Pfam SNARE associated Golgi protein
CU052_19565	COG2801	Transposase and inactivated derivatives
CU052_19575	COG1794	racemase activity, acting on amino acids and derivatives
CU052_19580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CU052_19595	COG1129	ABC transporter
CU052_19600	COG1172	Belongs to the binding-protein-dependent transport system permease family
CU052_19605	COG1879	ABC-type sugar transport system periplasmic component
CU052_19610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU052_19615	COG1609	Transcriptional regulator
CU052_19630	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
CU052_19645	COG4607	ABC-type enterochelin transport system periplasmic component
CU052_19650	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU052_19655	COG4605	iron ion homeostasis
CU052_19660	COG4604	ABC transporter, ATP-binding protein
CU052_19665	COG0789	Transcriptional regulator
CU052_19685	COG4206	TonB-dependent receptor
CU052_19710	COG0523	cobalamin synthesis protein
CU052_19715	COG3447	MASE1 domain protein
CU052_19715	COG5002	protein histidine kinase activity
CU052_19715	COG5001	Diguanylate cyclase
CU052_19720	COG0513	Belongs to the DEAD box helicase family
CU052_19740	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CU052_19745	COG1119	ATPase activity
CU052_19760	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CU052_19780	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CU052_19785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CU052_19895	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CU052_19910	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CU052_19915	COG0513	Belongs to the DEAD box helicase family
CU052_19925	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CU052_19930	COG0583	DNA-binding transcription factor activity
CU052_19940	COG1012	belongs to the aldehyde dehydrogenase family
CU052_19950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CU052_19985	COG1126	abc transporter atp-binding protein
CU052_19990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU052_19995	COG4215	(ABC) transporter
CU052_20000	COG4160	amino acid transport
CU052_20025	COG1053	succinate dehydrogenase
CU052_20025	COG0431	NADPH-dependent FMN reductase
CU052_20025	COG3976	FMN-binding domain protein
CU052_20075	COG0443	Heat shock 70 kDa protein
CU052_20080	COG2847	Copper chaperone PCu(A)C
CU052_20110	COG0745	RESPONSE REGULATOR receiver
CU052_20125	COG1785	Belongs to the alkaline phosphatase family
CU052_20145	COG3706	GGDEF domain
CU052_20155	COG0814	amino acid
CU052_20160	COG5002	protein histidine kinase activity
CU052_20160	COG5001	Diguanylate cyclase
CU052_20170	COG0243	molybdopterin cofactor binding
CU052_20180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CU052_20190	COG3707	response regulator
CU052_20200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CU052_20200	COG1116	anion transmembrane transporter activity
CU052_20205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CU052_20210	COG1116	anion transmembrane transporter activity
CU052_20215	COG2146	nitrite reductase [NAD(P)H] activity
CU052_20215	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CU052_20265	COG0739	heme binding
CU052_20275	COG3038	cytochrome b561
CU052_20300	COG0745	RESPONSE REGULATOR receiver
CU052_20320	COG0628	permease
CU052_20325	COG1024	Enoyl-CoA hydratase
CU052_20330	COG3706	GGDEF domain
CU052_20330	COG0745	RESPONSE REGULATOR receiver
CU052_20405	COG2067	long-chain fatty acid transport protein
CU052_20410	COG1234	tRNA 3'-trailer cleavage
CU052_20420	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CU052_20420	COG0069	glutamate synthase activity
CU052_20440	COG2755	lipolytic protein G-D-S-L family
CU052_20440	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CU052_20450	COG1902	pentaerythritol trinitrate reductase activity
CU052_20455	COG0346	lactoylglutathione lyase activity
CU052_20480	COG2815	serine threonine protein kinase
CU052_20480	COG0515	serine threonine protein kinase
CU052_20515	COG0631	protein serine/threonine phosphatase activity
CU052_20570	COG3501	Rhs element vgr protein
CU052_20585	COG3209	COG3209 Rhs family protein
CU052_20610	COG0420	3'-5' exonuclease activity
CU052_20615	COG0419	ATPase involved in DNA repair
CU052_20660	COG3040	lipid binding
CU052_20670	COG2814	Major facilitator Superfamily
CU052_20680	COG1288	antiporter activity
CU052_20690	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CU052_20705	COG2425	protein containing a von Willebrand factor type A (vWA) domain
CU052_20715	COG0583	DNA-binding transcription factor activity
CU052_20720	COG0277	FAD linked oxidase domain protein
CU052_20795	COG5001	Diguanylate cyclase
CU052_20800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CU052_20805	COG2146	nitrite reductase [NAD(P)H] activity
CU052_20810	COG2116	formate transmembrane transporter activity
CU052_20830	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
CU052_20870	COG2814	Major facilitator Superfamily
CU052_20875	COG3118	belongs to the thioredoxin family
CU052_20880	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CU052_20905	COG1566	PFAM secretion protein HlyD family protein
CU052_20915	COG0628	permease
CU052_20925	COG1482	cell wall glycoprotein biosynthetic process
CU052_20930	COG2271	Major facilitator Superfamily
CU052_20935	COG3851	Histidine kinase
CU052_20940	COG2197	response regulator
CU052_21000	COG1328	CTP reductase activity
CU052_21005	COG0602	queuosine metabolic process
CU052_21010	COG0534	Mate efflux family protein
CU052_21025	COG0189	ligase activity
CU052_21025	COG4067	protein conserved in archaea
CU052_21035	COG3111	PFAM Bacterial OB fold (BOF) protein
CU052_21045	COG0725	ABC transporter, periplasmic molybdate-binding protein
CU052_21050	COG4149	molybdate abc transporter
CU052_21055	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CU052_21065	COG4251	negative regulation of phosphorylation
CU052_21065	COG3706	GGDEF domain
CU052_21065	COG5001	Diguanylate cyclase
CU052_21065	COG2203	Gaf domain
CU052_21080	COG3706	GGDEF domain
CU052_21095	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CU052_21100	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CU052_21125	COG3140	Belongs to the UPF0181 family
CU052_21155	COG0023	Translation Initiation Factor
CU052_21175	COG1042	CoA-binding domain protein
CU052_21175	COG0045	succinate-CoA ligase (ADP-forming) activity
CU052_21175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CU052_21185	COG0583	DNA-binding transcription factor activity
CU052_21200	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CU052_21205	COG3447	MASE1 domain protein
CU052_21205	COG5001	Diguanylate cyclase
CU052_21205	COG5002	protein histidine kinase activity
CU052_21215	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CU052_21220	COG1984	allophanate hydrolase subunit 2
CU052_21230	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CU052_21235	COG4181	ATPase activity
CU052_21245	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
CU052_21250	COG3300	MHYT domain
CU052_21250	COG5001	Diguanylate cyclase
CU052_21260	COG0484	heat shock protein binding
CU052_21295	COG2050	protein possibly involved in aromatic compounds catabolism
CU052_21310	COG2067	long-chain fatty acid transport protein
CU052_21315	COG2267	carboxylic ester hydrolase activity
CU052_21350	COG0737	Belongs to the 5'-nucleotidase family
CU052_21355	COG3593	DNA synthesis involved in DNA repair
CU052_21365	COG0583	DNA-binding transcription factor activity
CU052_21375	COG2116	formate transmembrane transporter activity
CU052_21385	COG3038	cytochrome b561
CU052_21400	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CU052_21405	COG0513	Belongs to the DEAD box helicase family
CU052_21435	COG0546	phosphoglycolate phosphatase activity
CU052_21440	COG0784	Response regulator, receiver
CU052_21440	COG3437	response regulator, receiver
CU052_21455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU052_21465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CU052_21475	COG2207	Transcriptional regulator
CU052_21480	COG1979	alcohol dehydrogenase
CU052_21490	COG1126	abc transporter atp-binding protein
CU052_21495	COG0765	amino acid transport
CU052_21500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CU052_21505	COG0765	amino acid transport
CU052_21510	COG2199	diguanylate cyclase activity
CU052_21510	COG2200	EAL domain
CU052_21510	COG2203	Gaf domain
CU052_21525	COG1609	Transcriptional regulator
CU052_21530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_21530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_21535	COG1105	Belongs to the carbohydrate kinase PfkB family
CU052_21540	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CU052_21540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU052_21540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU052_21570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU052_21575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU052_21585	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CU052_21595	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CU052_21600	COG0509	glycine decarboxylation via glycine cleavage system
CU052_21615	COG2801	Transposase and inactivated derivatives
CU052_21715	COG2176	DNA-directed DNA polymerase activity
CU052_21725	COG1733	regulation of RNA biosynthetic process
CU052_21740	COG1132	(ABC) transporter
CU052_21770	COG2076	Multidrug Resistance protein
CU052_21785	COG0671	phosphoesterase, PA-phosphatase related
CU052_21790	COG1902	pentaerythritol trinitrate reductase activity
CU052_21790	COG0446	pyridine nucleotide-disulphide oxidoreductase
CU052_21800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CU052_21805	COG1845	cytochrome c oxidase, subunit III
CU052_21810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CU052_21815	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CU052_21825	COG1028	Short-chain dehydrogenase reductase Sdr
CU052_21835	COG1024	Enoyl-CoA hydratase
CU052_21840	COG1024	Enoyl-CoA hydratase
CU052_21855	COG0183	Belongs to the thiolase family
CU052_21865	COG1960	acyl-CoA dehydrogenase activity
CU052_21870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CU052_21875	COG1024	Enoyl-CoA hydratase
CU052_21915	COG3278	Belongs to the heme-copper respiratory oxidase family
CU052_21940	COG2962	Rard protein
CU052_21955	COG0835	chemotaxis
CU052_21955	COG0784	Response regulator, receiver
CU052_21965	COG0778	Nitroreductase
CU052_21975	COG2197	response regulator
CU052_21985	COG3706	GGDEF domain
CU052_21990	COG2197	response regulator
CU052_21995	COG5001	Diguanylate cyclase
CU052_21995	COG3300	MHYT domain
CU052_22000	COG2205	protein histidine kinase activity
CU052_22000	COG0784	Response regulator, receiver
CU052_22015	COG4771	TonB-dependent receptor
CU052_22020	COG1120	ATPase activity
CU052_22025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU052_22030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU052_22035	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CU052_22040	COG4772	TonB-dependent receptor
CU052_22065	COG4264	IucA IucC family
CU052_22070	COG0019	diaminopimelate decarboxylase activity
CU052_22075	COG2017	converts alpha-aldose to the beta-anomer
CU052_22080	COG1940	carbohydrate kinase activity
CU052_22085	COG0477	Major facilitator Superfamily
CU052_22085	COG2814	Major facilitator Superfamily
CU052_22090	COG0457	Tetratricopeptide repeat
CU052_22100	COG2801	Transposase and inactivated derivatives
CU052_22110	COG0739	heme binding
CU052_22115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CU052_22145	COG3069	C4-dicarboxylate transmembrane transporter activity
CU052_22150	COG1704	LemA family
CU052_22155	COG0501	Belongs to the peptidase M48B family
CU052_22180	COG0641	radical SAM
CU052_22200	COG3111	PFAM Bacterial OB fold (BOF) protein
CU052_22205	COG1597	lipid kinase activity
CU052_22210	COG0583	DNA-binding transcription factor activity
CU052_22220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CU052_22230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CU052_22290	COG0714	Associated with various cellular activities
CU052_22300	COG3119	arylsulfatase activity
CU052_22305	COG3119	arylsulfatase activity
CU052_22335	COG2205	protein histidine kinase activity
CU052_22335	COG2198	Histidine kinase
CU052_22335	COG0784	Response regulator, receiver
CU052_22340	COG1879	ABC-type sugar transport system periplasmic component
CU052_22350	COG0210	DNA helicase
CU052_22355	COG1289	transmembrane transporter activity
CU052_22390	COG3530	Putative quorum-sensing-regulated virulence factor
CU052_22430	COG3186	Phenylalanine-4-hydroxylase
CU052_22440	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CU052_22445	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CU052_22465	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
CU052_22475	COG1454	alcohol dehydrogenase
CU052_22480	COG2133	pyrroloquinoline quinone binding
CU052_22485	COG1619	proteins homologs of microcin C7 resistance protein MccF
CU052_22495	COG0783	Belongs to the Dps family
CU052_22500	COG0840	transmembrane signaling receptor activity
CU052_22525	COG2205	protein histidine kinase activity
CU052_22525	COG0784	Response regulator, receiver
CU052_22530	COG1538	Outer membrane efflux protein
CU052_22560	COG1136	(ABC) transporter
CU052_22560	COG0577	efflux transmembrane transporter activity
CU052_22580	COG2199	diguanylate cyclase activity
CU052_22590	COG3036	rescue of stalled ribosome
CU052_22595	COG1278	Cold shock
CU052_22660	COG3504	Conjugal transfer protein
CU052_22720	COG3730	PTS system glucitol sorbitol-specific
CU052_22725	COG1349	DNA-binding transcription factor activity
CU052_22730	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_22735	COG1028	Short-chain dehydrogenase reductase Sdr
CU052_22750	COG3730	PTS system glucitol sorbitol-specific
CU052_22755	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CU052_22755	COG0517	IMP dehydrogenase activity
CU052_22775	COG0515	serine threonine protein kinase
CU052_22775	COG3064	Membrane
CU052_22775	COG4991	sh3 domain protein
CU052_22800	COG1716	ATPase activity
CU052_22820	COG1181	Belongs to the D-alanine--D-alanine ligase family
CU052_22975	COG1388	LysM domain
CU052_22975	COG4932	domain protein
CU052_22975	COG2373	Large extracellular alpha-helical protein
CU052_22985	COG3969	phosphoadenosine phosphosulfate
CU052_22990	COG1475	DNA binding
CU052_23020	COG3152	Membrane
CU052_23045	COG1742	UPF0060 membrane protein
CU052_23050	COG4974	Belongs to the 'phage' integrase family
CU052_23060	COG2885	chlorophyll binding
CU052_23070	COG0545	Peptidyl-prolyl cis-trans isomerase
CU052_23100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CU052_23110	COG0840	transmembrane signaling receptor activity
CU052_23130	COG2195	Cleaves the N-terminal amino acid of tripeptides
CU052_23145	COG2197	response regulator
CU052_23150	COG3850	Histidine kinase
CU052_23155	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CU052_23175	COG3005	denitrification pathway
CU052_23200	COG0183	Belongs to the thiolase family
CU052_23210	COG1280	lysine exporter protein (LysE YggA)
CU052_23220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CU052_23225	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CU052_23295	COG2926	Belongs to the UPF0265 family
CU052_23300	COG0534	Mate efflux family protein
CU052_23305	COG0673	inositol 2-dehydrogenase activity
CU052_23315	COG2205	protein histidine kinase activity
CU052_23315	COG5002	protein histidine kinase activity
CU052_23315	COG0784	Response regulator, receiver
CU052_23335	COG0583	DNA-binding transcription factor activity
CU052_23345	COG1522	sequence-specific DNA binding
CU052_23350	COG0531	amino acid
CU052_23355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU052_23365	COG2205	protein histidine kinase activity
CU052_23370	COG0745	RESPONSE REGULATOR receiver
CU052_23395	COG1566	PFAM secretion protein HlyD family protein
CU052_23400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CU052_23405	COG2239	Acts as a magnesium transporter
CU052_23410	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CU052_23415	COG0402	S-adenosylhomocysteine deaminase activity
CU052_23430	COG1418	mRNA catabolic process
CU052_23445	COG2814	Major facilitator Superfamily
CU052_23455	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CU052_23475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CU052_23490	COG4221	oxidoreductase activity
CU052_23505	COG3976	FMN-binding domain protein
CU052_23505	COG1053	succinate dehydrogenase
CU052_23510	COG4948	Mandelate Racemase Muconate Lactonizing
CU052_23515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CU052_23520	COG0745	RESPONSE REGULATOR receiver
CU052_23525	COG2205	protein histidine kinase activity
CU052_23535	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CU052_23540	COG2194	sulfuric ester hydrolase activity
CU052_23550	COG4977	sequence-specific DNA binding
CU052_23555	COG1335	isochorismatase
CU052_23565	COG2814	Major facilitator Superfamily
CU052_23585	COG0583	DNA-binding transcription factor activity
CU052_23625	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CU052_23635	COG0633	Ferredoxin
CU052_23635	COG3217	Mosc domain protein beta barrel domain protein
CU052_23635	COG0633	Ferredoxin
CU052_23635	COG3217	Mosc domain protein beta barrel domain protein
CU052_23640	COG0401	homolog of Blt101
CU052_23655	COG2354	Protein conserved in bacteria
CU052_23665	COG4753	response regulator
CU052_23665	COG2207	Transcriptional regulator
CU052_23680	COG0741	lytic transglycosylase activity
CU052_23730	COG1175	transmembrane transport
CU052_23745	COG3842	ATPase activity
CU052_23765	COG3206	protein involved in exopolysaccharide biosynthesis
CU052_23765	COG0489	protein tyrosine kinase activity
CU052_23775	COG0438	transferase activity, transferring glycosyl groups
CU052_23805	COG1309	transcriptional regulator
CU052_23810	COG2130	NADP-dependent
CU052_23820	COG0753	catalase activity
CU052_23825	COG2084	Dehydrogenase
CU052_23835	COG0583	DNA-binding transcription factor activity
CU052_23840	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU052_23845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU052_23855	COG2207	Transcriptional regulator
CU052_23860	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_23860	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU052_23860	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CU052_23875	COG0583	DNA-binding transcription factor activity
CU052_23880	COG1566	PFAM secretion protein HlyD family protein
CU052_23915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CU052_23925	COG0583	DNA-binding transcription factor activity
CU052_23930	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
CU052_23930	COG2207	Transcriptional regulator
CU052_23935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU052_23955	COG0095	Lipoate-protein ligase
CU052_23975	COG0513	Belongs to the DEAD box helicase family
CU052_23980	COG2801	Transposase and inactivated derivatives
CU052_23990	COG0583	DNA-binding transcription factor activity
CU052_24015	COG1028	Short-chain dehydrogenase reductase Sdr
CU052_24020	COG2814	Major facilitator Superfamily
CU052_24030	COG1902	pentaerythritol trinitrate reductase activity
CU052_24045	COG3122	Protein conserved in bacteria
CU052_24065	COG0583	DNA-binding transcription factor activity
CU052_24080	COG0252	asparaginase activity
CU052_24090	COG0574	Belongs to the PEP-utilizing enzyme family
CU052_24090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CU052_24100	COG2197	response regulator
CU052_24105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CU052_24120	COG0583	DNA-binding transcription factor activity
CU052_24125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CU052_24135	COG1538	Outer membrane efflux protein
CU052_24140	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CU052_24145	COG0786	glutamate:sodium symporter activity
CU052_24180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CU052_24190	COG2801	Transposase and inactivated derivatives
CU052_24235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CU052_24245	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CU052_24285	COG3338	carbonate dehydratase activity
CU052_24315	COG1063	alcohol dehydrogenase
CU052_24320	COG0156	8-amino-7-oxononanoate synthase activity
CU052_24345	COG0745	RESPONSE REGULATOR receiver
CU052_24370	COG0346	lactoylglutathione lyase activity
CU052_24415	COG2200	EAL domain
CU052_24435	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CU052_24450	COG2204	response regulator
CU052_24475	COG1987	bacterial-type flagellum assembly
CU052_24485	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CU052_24500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CU052_24510	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CU052_24515	COG1516	flagellar protein fliS
CU052_24530	COG1580	Controls the rotational direction of flagella during chemotaxis
CU052_24535	COG1191	sigma factor activity
CU052_24540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CU052_24545	COG1360	Flagellar Motor Protein
CU052_24610	COG1136	(ABC) transporter
CU052_24635	COG0672	)-iron permease
CU052_24655	COG2226	methyltransferase
CU052_24670	COG3710	Transcriptional regulator
CU052_24675	COG1253	flavin adenine dinucleotide binding
CU052_24710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CU052_24715	COG4786	Flagellar basal body rod
CU052_24715	COG1256	bacterial-type flagellum assembly
CU052_24725	COG1706	bacterial-type flagellum-dependent cell motility
CU052_24730	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CU052_24735	COG4786	Flagellar basal body rod
CU052_24740	COG4787	bacterial-type flagellum-dependent cell motility
CU052_24745	COG1749	Flagellar hook protein flgE
CU052_24750	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CU052_24755	COG1558	bacterial-type flagellum-dependent cell motility
CU052_24760	COG1815	bacterial-type flagellum-dependent cell motility
CU052_24780	COG0741	lytic transglycosylase activity
CU052_24780	COG1388	LysM domain
CU052_24805	COG2801	Transposase and inactivated derivatives
CU052_24815	COG1760	l-serine dehydratase
CU052_24845	COG0583	DNA-binding transcription factor activity
CU052_24855	COG2866	Carboxypeptidase
CU052_24860	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CU052_24875	COG2990	Protein conserved in bacteria
CU052_24900	COG3842	ATPase activity
CU052_24905	COG1840	ABC-type Fe3 transport system, periplasmic component
CU052_24925	COG1609	Transcriptional regulator
CU052_24955	COG3240	lipase activity
CU052_24990	COG1011	Hydrolase
CU052_25040	COG1765	OsmC-like protein
CU052_25070	COG1765	OsmC-like protein
CU052_25075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CU052_25075	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CU052_25090	COG3046	protein related to deoxyribodipyrimidine photolyase
CU052_25095	COG0415	Belongs to the DNA photolyase family
CU052_25100	COG3706	GGDEF domain
CU052_25115	COG3706	GGDEF domain
CU052_25135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CU052_25140	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CU052_25160	COG3033	Beta-eliminating lyase
CU052_25180	COG3179	chitinase
CU052_25190	COG0579	oxidoreductase
CU052_25215	COG1114	Component of the transport system for branched-chain amino acids
CU052_25255	COG0583	DNA-binding transcription factor activity
CU052_25280	COG0189	ligase activity
CU052_25285	COG4067	protein conserved in archaea
CU052_25285	COG0189	ligase activity
CU052_25295	COG1166	arginine decarboxylase activity
CU052_25300	COG0010	Belongs to the arginase family
CU052_25305	COG2814	Major facilitator Superfamily
CU052_25310	COG1770	oligopeptidase
CU052_25330	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CU052_25335	COG1121	(ABC) transporter
CU052_25340	COG0803	Belongs to the bacterial solute-binding protein 9 family
CU052_25385	COG0848	biopolymer transport protein
CU052_25390	COG0811	peptide transport
CU052_25395	COG0811	peptide transport
CU052_25415	COG0745	RESPONSE REGULATOR receiver
CU052_25425	COG0584	glycerophosphoryl diester phosphodiesterase
CU052_25435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CU052_25490	COG0312	modulator of DNA gyrase
CU052_25495	COG0312	modulator of DNA gyrase
CU052_25500	COG0351	phosphomethylpyrimidine kinase
CU052_25505	COG1116	anion transmembrane transporter activity
CU052_25510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CU052_25515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CU052_25520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CU052_25535	COG0671	phosphoesterase, PA-phosphatase related
CU052_25540	COG0243	molybdopterin cofactor binding
CU052_25545	COG3005	denitrification pathway
CU052_25575	COG0456	acetyltransferase
CU052_25620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU052_25625	COG2356	endonuclease I
CU052_25655	COG2199	diguanylate cyclase activity
CU052_25655	COG2203	Gaf domain
CU052_25675	COG2221	Nitrite and sulphite reductase 4Fe-4S
CU052_25680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CU052_25695	COG2814	Major facilitator Superfamily
CU052_25715	COG4771	TonB-dependent receptor
CU052_25720	COG0583	DNA-binding transcription factor activity
CU052_25725	COG4607	ABC-type enterochelin transport system periplasmic component
CU052_25730	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CU052_25735	COG4605	iron ion homeostasis
CU052_25740	COG4604	ABC transporter, ATP-binding protein
CU052_25765	COG0739	heme binding
CU052_25790	COG0612	Peptidase, M16
CU052_25795	COG0840	transmembrane signaling receptor activity
CU052_25810	COG1764	response to oxidative stress
CU052_25815	COG1846	Transcriptional regulator
CU052_25825	COG0450	alkyl hydroperoxide reductase
CU052_25830	COG3634	alkyl hydroperoxide reductase activity
CU052_25865	COG0583	DNA-binding transcription factor activity
CU052_25870	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CU052_25885	COG0583	DNA-binding transcription factor activity
CU052_25935	COG0346	lactoylglutathione lyase activity
CU052_25955	COG1522	sequence-specific DNA binding
CU052_25970	COG2258	MOSC domain
CU052_25975	COG2153	protein acetylation
CU052_25985	COG3713	MltA-interacting MipA family protein
CU052_25990	COG0513	Belongs to the DEAD box helicase family
CU052_26000	COG1595	DNA-templated transcription, initiation
CU052_26005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CU052_26020	COG3655	Transcriptional regulator
CU052_26025	COG1312	Catalyzes the dehydration of D-mannonate
CU052_26030	COG2186	Transcriptional regulator
CU052_26040	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CU052_26050	COG0246	Mannitol dehydrogenase
CU052_26055	COG1904	glucuronate isomerase
CU052_26060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU052_26065	COG0800	Aldolase
CU052_26080	COG0549	Belongs to the carbamate kinase family
CU052_26085	COG0531	amino acid
CU052_26090	COG2957	Belongs to the agmatine deiminase family
CU052_26115	COG2149	membrane
CU052_26120	COG3119	arylsulfatase activity
CU052_26135	COG0800	Aldolase
CU052_26140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU052_26145	COG1028	Short-chain dehydrogenase reductase Sdr
CU052_26150	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CU052_26160	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
CU052_26165	COG4580	involved in the transport of maltose and maltodextrins
CU052_26170	COG0641	radical SAM
CU052_26180	COG0517	IMP dehydrogenase activity
CU052_26180	COG0516	GMP reductase activity
CU052_26195	COG1132	(ABC) transporter
CU052_26255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CU052_26330	COG4166	transmembrane transport
CU052_26360	COG1595	DNA-templated transcription, initiation
CU052_26395	COG0811	peptide transport
CU052_26400	COG0848	biopolymer transport protein
CU052_26405	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CU052_26410	COG1444	tRNA N-acetyltransferase activity
CU052_26435	COG4608	Belongs to the ABC transporter superfamily
CU052_26440	COG0444	Belongs to the ABC transporter superfamily
CU052_26450	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
CU052_26450	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CU052_26475	COG0772	Belongs to the SEDS family
CU052_26490	COG1566	PFAM secretion protein HlyD family protein
CU052_26495	COG0583	DNA-binding transcription factor activity
CU052_26530	COG2801	Transposase and inactivated derivatives
CU052_26545	COG3275	phosphorelay sensor kinase activity
CU052_26550	COG3279	Response regulator of the LytR AlgR family
CU052_26560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CU052_26585	COG0786	glutamate:sodium symporter activity
CU052_26600	COG1131	(ABC) transporter
CU052_26605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CU052_26610	COG0786	glutamate:sodium symporter activity
CU052_26640	COG0561	phosphatase activity
CU052_26645	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
CU052_26650	COG3623	hexulose-6-phosphate isomerase
CU052_26690	COG2259	Doxx family
CU052_26700	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CU052_26705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CU052_26740	COG1136	(ABC) transporter
CU052_26750	COG1349	DNA-binding transcription factor activity
CU052_26755	COG1349	DNA-binding transcription factor activity
CU052_26765	COG2222	sugar isomerase
CU052_26770	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU052_26780	COG3716	PTS system mannose fructose sorbose family IID component
CU052_26785	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
CU052_26795	COG0191	fructose-bisphosphate aldolase activity
CU052_26815	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CU052_26880	COG5001	Diguanylate cyclase
CU052_26885	COG4580	involved in the transport of maltose and maltodextrins
CU052_26890	COG1609	Transcriptional regulator
CU052_26905	COG0395	ABC-type sugar transport system, permease component
CU052_26910	COG2723	6-phospho-beta-galactosidase activity
CU052_26915	COG3842	ATPase activity
CU052_26920	COG1609	Transcriptional regulator
CU052_26925	COG0534	Mate efflux family protein
CU052_26930	COG0564	pseudouridine synthase activity
CU052_26935	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CU052_26945	COG0561	phosphatase activity
CU052_26955	COG2199	diguanylate cyclase activity
CU052_26965	COG3152	Membrane
CU052_26980	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CU052_26995	COG0583	DNA-binding transcription factor activity
CU052_27030	COG2076	Multidrug Resistance protein
CU052_27055	COG1357	PFAM Pentapeptide repeats (8 copies)
CU052_27060	COG3047	cAMP biosynthetic process
CU052_27080	COG2814	Major facilitator Superfamily
CU052_27140	COG4771	TonB-dependent receptor
CU052_27145	COG1132	(ABC) transporter
CU052_27150	COG1132	(ABC) transporter
CU052_27285	COG1228	amidohydrolase
CU052_27295	COG3835	regulator
CU052_27300	COG1929	Belongs to the glycerate kinase type-1 family
CU052_27320	COG1982	Orn Lys Arg decarboxylase major
CU052_27325	COG0531	amino acid
CU052_27355	COG0183	Belongs to the thiolase family
CU052_27370	COG0583	DNA-binding transcription factor activity
CU052_27375	COG0477	Major facilitator Superfamily
CU052_27375	COG2814	Major facilitator Superfamily
CU052_27385	COG3962	Belongs to the TPP enzyme family
CU052_27390	COG0673	inositol 2-dehydrogenase activity
CU052_27395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CU052_27420	COG0673	inositol 2-dehydrogenase activity
CU052_27425	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CU052_27430	COG1162	GTPase activity
CU052_27435	COG1263	PTS System
CU052_27435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CU052_27470	COG0058	SHG alpha-glucan phosphorylase activity
CU052_27480	COG1640	4-alpha-glucanotransferase
CU052_27485	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CU052_27490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CU052_27495	COG0366	Alpha amylase catalytic
CU052_27510	COG3366	ferrous iron transmembrane transporter activity
CU052_27515	COG0700	Nucleoside recognition
CU052_27520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CU052_27525	COG3339	Conserved Protein
CU052_27540	COG1301	dicarboxylic acid transport
CU052_27575	COG0583	DNA-binding transcription factor activity
CU052_27610	COG2095	MarC family integral membrane protein
CU052_27615	COG1349	DNA-binding transcription factor activity
CU052_27620	COG0738	Major facilitator superfamily
CU052_27625	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
CU052_27630	COG1070	Carbohydrate kinase
CU052_27635	COG4154	Belongs to the RbsD FucU family
CU052_27640	COG0235	Class ii aldolase
CU052_27645	COG1454	alcohol dehydrogenase
CU052_27670	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CU052_27675	COG2801	Transposase and inactivated derivatives
CU052_27680	COG0415	Belongs to the DNA photolyase family
CU052_27695	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CU052_27700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CU052_27720	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CU052_27735	COG1686	Belongs to the peptidase S11 family
CU052_27760	COG0583	DNA-binding transcription factor activity
CU052_27765	COG4628	conserved protein (DUF2132)
CU052_27775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CU052_27790	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CU052_27795	COG0628	permease
CU052_27835	COG2988	succinylglutamate desuccinylase activity
CU052_27855	COG2814	Major facilitator Superfamily
CU052_27865	COG0454	-acetyltransferase
CU052_27875	COG0745	RESPONSE REGULATOR receiver
CU052_27880	COG2205	protein histidine kinase activity
CU052_27895	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CU052_27935	COG1271	oxidase subunit
CU052_27950	COG3220	belongs to the UPF0276 family
CU052_27965	COG0384	phenazine biosynthesis protein PhzF
CU052_27970	COG0346	lactoylglutathione lyase activity
CU052_27985	COG0488	(ABC) transporter
CU052_27990	COG4628	conserved protein (DUF2132)
CU052_27995	COG0583	DNA-binding transcription factor activity
CU052_28000	COG0431	NADPH-dependent FMN reductase
CU052_28005	COG0435	Glutathione S-transferase
CU052_28010	COG0488	(ABC) transporter
CU052_28025	COG0583	DNA-binding transcription factor activity
CU052_28030	COG3226	Transcriptional regulator
CU052_28045	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CU052_28050	COG1280	lysine exporter protein (LysE YggA)
CU052_28095	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CU052_28130	COG0640	Transcriptional regulator
CU052_28180	COG4974	Belongs to the 'phage' integrase family
CU052_28185	COG0517	IMP dehydrogenase activity
CU052_28210	COG2003	Belongs to the UPF0758 family
CU052_28265	COG3423	Transcriptional regulator
CU052_28450	COG3209	COG3209 Rhs family protein
CU052_28525	COG1357	PFAM Pentapeptide repeats (8 copies)
CU052_28575	COG1192	Involved in chromosome partitioning
CU052_28680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CU052_28765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CU052_28780	COG0681	Belongs to the peptidase S26 family
CU052_28830	COG0714	Associated with various cellular activities
CU052_28890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CU052_28980	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CU052_29145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate