locus-tag	class	description
AL538_00010	COG2204	response regulator
AL538_00030	COG2885	chlorophyll binding
AL538_00040	COG1793	dna ligase
AL538_00050	COG0534	Mate efflux family protein
AL538_00055	COG0307	riboflavin synthase, alpha
AL538_00070	COG2201	protein-glutamate methylesterase activity
AL538_00075	COG3706	GGDEF domain
AL538_00085	COG2916	Histone family protein nucleoid-structuring protein H-NS
AL538_00110	COG0840	transmembrane signaling receptor activity
AL538_00120	COG0840	transmembrane signaling receptor activity
AL538_00165	COG1454	alcohol dehydrogenase
AL538_00180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL538_00185	COG1063	alcohol dehydrogenase
AL538_00195	COG3119	arylsulfatase activity
AL538_00200	COG0641	radical SAM
AL538_00205	COG0714	Associated with various cellular activities
AL538_00275	COG2003	Belongs to the UPF0758 family
AL538_00310	COG1203	CRISPR-associated helicase, Cas3
AL538_00340	COG1518	maintenance of DNA repeat elements
AL538_00345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL538_00405	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL538_00435	COG3710	Transcriptional regulator
AL538_00450	COG4790	Type iii secretion
AL538_00515	COG0791	NLP P60 protein
AL538_00520	COG0840	transmembrane signaling receptor activity
AL538_00525	COG3385	transposase activity
AL538_00570	COG1940	carbohydrate kinase activity
AL538_00580	COG0303	'Molybdopterin
AL538_00590	COG3842	ATPase activity
AL538_00595	COG4662	Binding-protein-dependent transport system inner membrane component
AL538_00605	COG2204	response regulator
AL538_00610	COG4191	Histidine kinase
AL538_00625	COG0488	(ABC) transporter
AL538_00630	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL538_00650	COG3381	protein complex oligomerization
AL538_00660	COG3383	formate dehydrogenase (NAD+) activity
AL538_00660	COG0243	molybdopterin cofactor binding
AL538_00665	COG0437	4 iron, 4 sulfur cluster binding
AL538_00685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL538_00690	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL538_00695	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL538_00700	COG1177	transmembrane transport
AL538_00705	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL538_00710	COG3842	ATPase activity
AL538_00720	COG2992	FlgJ-related protein
AL538_00735	COG0589	response to stress
AL538_00740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL538_00755	COG2217	Heavy metal translocating P-type atpase
AL538_00765	COG2010	Cytochrome c
AL538_00780	COG3278	Belongs to the heme-copper respiratory oxidase family
AL538_00825	COG1067	ATP-dependent peptidase activity
AL538_00830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL538_00870	COG2902	Dehydrogenase
AL538_00875	COG0308	aminopeptidase N
AL538_00890	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
AL538_00895	COG1956	GAF domain-containing protein
AL538_00900	COG1132	(ABC) transporter
AL538_00905	COG2995	paraquat-inducible protein a
AL538_00910	COG3008	intermembrane lipid transfer
AL538_00935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL538_00950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL538_00955	COG4597	amino acid ABC transporter
AL538_00960	COG0765	amino acid transport
AL538_00965	COG1126	abc transporter atp-binding protein
AL538_00970	COG0670	Belongs to the BI1 family
AL538_00975	COG2920	part of a sulfur-relay system
AL538_00980	COG1254	Belongs to the acylphosphatase family
AL538_01010	COG3300	MHYT domain
AL538_01010	COG5001	Diguanylate cyclase
AL538_01015	COG3850	Histidine kinase
AL538_01015	COG3437	response regulator, receiver
AL538_01015	COG4999	Histidine kinase
AL538_01015	COG2205	protein histidine kinase activity
AL538_01030	COG0110	maltose O-acetyltransferase activity
AL538_01050	COG1846	Transcriptional regulator
AL538_01060	COG3247	response to pH
AL538_01065	COG0668	transmembrane transport
AL538_01075	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AL538_01135	COG4964	Belongs to the GSP D family
AL538_01160	COG2207	Transcriptional regulator
AL538_01180	COG0589	response to stress
AL538_01185	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL538_01190	COG0363	glucosamine-6-phosphate deaminase activity
AL538_01195	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AL538_01200	COG4977	sequence-specific DNA binding
AL538_01205	COG4774	siderophore transport
AL538_01210	COG4565	transcriptional regulatory protein
AL538_01215	COG3290	protein histidine kinase activity
AL538_01230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL538_01260	COG0583	DNA-binding transcription factor activity
AL538_01275	COG3005	denitrification pathway
AL538_01290	COG1999	signal sequence binding
AL538_01295	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL538_01315	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL538_01345	COG2186	Transcriptional regulator
AL538_01360	COG0702	epimerase
AL538_01365	COG0583	DNA-binding transcription factor activity
AL538_01370	COG1404	Belongs to the peptidase S8 family
AL538_01375	COG1858	cytochrome C peroxidase
AL538_01385	COG0527	aspartate kinase activity
AL538_01390	COG0662	Cupin 2, conserved barrel domain protein
AL538_01395	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AL538_01400	COG0456	acetyltransferase
AL538_01405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL538_01415	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AL538_01420	COG0534	Mate efflux family protein
AL538_01435	COG1368	sulfuric ester hydrolase activity
AL538_01465	COG1115	amino acid carrier protein
AL538_01470	COG1012	belongs to the aldehyde dehydrogenase family
AL538_01475	COG3284	Transcriptional regulator
AL538_01505	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AL538_01510	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
AL538_01515	COG3051	citrate lyase alpha subunit
AL538_01520	COG2301	Belongs to the HpcH HpaI aldolase family
AL538_01525	COG3052	prosthetic group binding
AL538_01530	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
AL538_01540	COG3630	sodium ion export across plasma membrane
AL538_01545	COG5016	pyruvate
AL538_01545	COG0511	ligase activity, forming carbon-carbon bonds
AL538_01550	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AL538_01560	COG4565	transcriptional regulatory protein
AL538_01600	COG1051	belongs to the nudix hydrolase family
AL538_01650	COG0625	glutathione transferase activity
AL538_01660	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AL538_01675	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL538_01685	COG0601	transmembrane transport
AL538_01690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL538_01695	COG0444	Belongs to the ABC transporter superfamily
AL538_01715	COG3291	Pkd domain containing protein
AL538_01730	COG0745	RESPONSE REGULATOR receiver
AL538_01740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL538_01745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL538_01765	COG0813	purine-nucleoside phosphorylase activity
AL538_01775	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL538_01780	COG3842	ATPase activity
AL538_01785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL538_01790	COG2423	ornithine cyclodeaminase activity
AL538_01805	COG3938	Belongs to the proline racemase family
AL538_01825	COG3706	GGDEF domain
AL538_01825	COG0745	RESPONSE REGULATOR receiver
AL538_01835	COG1451	nucleotide metabolic process
AL538_01850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL538_01865	COG0583	DNA-binding transcription factor activity
AL538_01925	COG4139	cobalamin transport
AL538_01940	COG2062	phosphohistidine phosphatase, SixA
AL538_01950	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AL538_01960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AL538_01965	COG0702	epimerase
AL538_01980	COG2925	Exonuclease
AL538_01990	COG1346	cytolysis
AL538_02055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL538_02055	COG0072	phenylalanine-tRNA ligase activity
AL538_02065	COG3706	GGDEF domain
AL538_02110	COG0251	oxidation-reduction process
AL538_02120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL538_02145	COG2188	Transcriptional regulator
AL538_02155	COG0010	Belongs to the arginase family
AL538_02165	COG2986	histidine ammonia-lyase
AL538_02180	COG0277	FAD linked oxidase domain protein
AL538_02180	COG0247	lactate metabolic process
AL538_02215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL538_02255	COG0456	acetyltransferase
AL538_02490	COG2026	Addiction module toxin, RelE StbE family
AL538_02510	COG1403	HNH endonuclease
AL538_02525	COG0625	glutathione transferase activity
AL538_02540	COG3385	transposase activity
AL538_02715	COG3340	Belongs to the peptidase S51 family
AL538_02925	COG0110	maltose O-acetyltransferase activity
AL538_02945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL538_02960	COG3106	COG3106 Predicted ATPase
AL538_02975	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL538_02980	COG0784	Response regulator, receiver
AL538_02980	COG2205	protein histidine kinase activity
AL538_02995	COG0814	amino acid
AL538_03000	COG1760	l-serine dehydratase
AL538_03005	COG5001	Diguanylate cyclase
AL538_03005	COG3300	MHYT domain
AL538_03015	COG2197	response regulator
AL538_03020	COG0720	synthase
AL538_03025	COG0840	transmembrane signaling receptor activity
AL538_03030	COG0017	Asparaginyl-tRNA synthetase
AL538_03045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL538_03060	COG3437	response regulator, receiver
AL538_03060	COG2770	Histidine kinase
AL538_03065	COG1448	Aminotransferase
AL538_03085	COG0840	transmembrane signaling receptor activity
AL538_03090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL538_03095	COG1846	Transcriptional regulator
AL538_03120	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL538_03135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL538_03140	COG3108	Peptidase M15
AL538_03145	COG2989	Protein conserved in bacteria
AL538_03170	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL538_03180	COG4235	cytochrome complex assembly
AL538_03180	COG3088	subunit of a heme lyase
AL538_03190	COG1138	Cytochrome C-type biogenesis protein
AL538_03195	COG3301	Polysulphide reductase, NrfD
AL538_03200	COG0437	4 iron, 4 sulfur cluster binding
AL538_03210	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AL538_03230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL538_03240	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL538_03245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL538_03270	COG0019	diaminopimelate decarboxylase activity
AL538_03315	COG0322	excinuclease ABC activity
AL538_03320	COG2197	response regulator
AL538_03325	COG0417	DNA replication proofreading
AL538_03345	COG1187	pseudouridine synthase activity
AL538_03355	COG0009	L-threonylcarbamoyladenylate synthase
AL538_03360	COG0613	PHP domain protein
AL538_03370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AL538_03375	COG0512	Glutamine amidotransferase of anthranilate synthase
AL538_03385	COG0135	phosphoribosylanthranilate isomerase activity
AL538_03385	COG0134	indole-3-glycerol-phosphate synthase activity
AL538_03395	COG0159	tryptophan synthase activity
AL538_03400	COG1301	dicarboxylic acid transport
AL538_03425	COG1607	acyl-coa hydrolase
AL538_03430	COG2350	Protein conserved in bacteria
AL538_03445	COG0583	DNA-binding transcription factor activity
AL538_03460	COG1716	ATPase activity
AL538_03460	COG5001	Diguanylate cyclase
AL538_03465	COG1032	radical SAM domain protein
AL538_03470	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL538_03485	COG2964	Protein conserved in bacteria
AL538_03490	COG0840	transmembrane signaling receptor activity
AL538_03500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AL538_03505	COG0463	Glycosyl transferase, family 2
AL538_03510	COG0745	RESPONSE REGULATOR receiver
AL538_03515	COG3850	Histidine kinase
AL538_03515	COG5002	protein histidine kinase activity
AL538_03550	COG1846	Transcriptional regulator
AL538_03565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AL538_03595	COG1136	(ABC) transporter
AL538_03595	COG0577	efflux transmembrane transporter activity
AL538_03605	COG0577	efflux transmembrane transporter activity
AL538_03630	COG3153	acetyltransferase
AL538_03655	COG3118	belongs to the thioredoxin family
AL538_03660	COG4232	protein-disulfide reductase activity
AL538_03675	COG2995	paraquat-inducible protein a
AL538_03680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL538_03680	COG3008	intermembrane lipid transfer
AL538_03685	COG3009	Protein conserved in bacteria
AL538_03740	COG4166	transmembrane transport
AL538_03750	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL538_03755	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
AL538_03765	COG0539	negative regulation of cytoplasmic translation
AL538_03775	COG0616	signal peptide processing
AL538_03780	COG1028	Short-chain dehydrogenase reductase Sdr
AL538_03790	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL538_03820	COG0784	Response regulator, receiver
AL538_03820	COG0835	chemotaxis
AL538_03825	COG1940	carbohydrate kinase activity
AL538_03835	COG4667	esterase of the alpha-beta hydrolase superfamily
AL538_03845	COG0733	neurotransmitter:sodium symporter activity
AL538_03855	COG1263	PTS System
AL538_03855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL538_03860	COG0084	hydrolase, TatD family'
AL538_03875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL538_03905	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL538_03920	COG1399	metal-binding, possibly nucleic acid-binding protein
AL538_03925	COG0424	maF-like protein
AL538_03930	COG0564	pseudouridine synthase activity
AL538_03935	COG1530	ribonuclease E activity
AL538_03945	COG0659	secondary active sulfate transmembrane transporter activity
AL538_03950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL538_03955	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AL538_03985	COG2186	Transcriptional regulator
AL538_03995	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL538_04000	COG0653	protein targeting
AL538_04005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL538_04010	COG3706	GGDEF domain
AL538_04015	COG0366	Alpha amylase catalytic
AL538_04020	COG1122	ATPase activity
AL538_04025	COG4120	Belongs to the binding-protein-dependent transport system permease family
AL538_04050	COG0280	phosphate acetyltransferase
AL538_04050	COG0857	belongs to the CobB CobQ family
AL538_04055	COG3174	membrane
AL538_04060	COG0435	Glutathione S-transferase
AL538_04070	COG0444	Belongs to the ABC transporter superfamily
AL538_04075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL538_04080	COG0601	transmembrane transport
AL538_04090	COG0314	molybdopterin synthase activity
AL538_04095	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL538_04105	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL538_04110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL538_04115	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AL538_04130	COG0556	nucleotide-excision repair
AL538_04140	COG1882	Formate acetyltransferase
AL538_04145	COG4657	Part of a membrane complex involved in electron transport
AL538_04155	COG4656	Part of a membrane complex involved in electron transport
AL538_04160	COG4658	electron transport chain
AL538_04165	COG4659	FMN binding
AL538_04170	COG4660	Part of a membrane complex involved in electron transport
AL538_04175	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL538_04180	COG0346	lactoylglutathione lyase activity
AL538_04190	COG2885	chlorophyll binding
AL538_04200	COG2056	Na+-H+ antiporter family
AL538_04235	COG3451	type IV secretory pathway VirB4
AL538_04255	COG3736	Type IV secretory pathway, component VirB8
AL538_04260	COG3504	Conjugal transfer protein
AL538_04285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL538_04290	COG1683	Conserved Protein
AL538_04310	COG0583	DNA-binding transcription factor activity
AL538_04320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL538_04325	COG0581	inorganic phosphate transmembrane transporter activity
AL538_04330	COG0573	inorganic phosphate transmembrane transporter activity
AL538_04335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL538_04415	COG0326	Molecular chaperone. Has ATPase activity
AL538_04430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL538_04465	COG2885	chlorophyll binding
AL538_04465	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AL538_04525	COG4974	Belongs to the 'phage' integrase family
AL538_04530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL538_04550	COG1012	belongs to the aldehyde dehydrogenase family
AL538_04550	COG1454	alcohol dehydrogenase
AL538_04555	COG2095	MarC family integral membrane protein
AL538_04560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL538_04565	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL538_04570	COG1757	Na H antiporter
AL538_04595	COG3083	sulfuric ester hydrolase activity
AL538_04605	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL538_04620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL538_04625	COG0778	Nitroreductase
AL538_04630	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL538_04630	COG1902	pentaerythritol trinitrate reductase activity
AL538_04635	COG0616	signal peptide processing
AL538_04640	COG0252	asparaginase activity
AL538_04645	COG3139	Protein of unknown function (DUF1315)
AL538_04655	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL538_04660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL538_04680	COG2226	methyltransferase
AL538_04700	COG1785	Belongs to the alkaline phosphatase family
AL538_04710	COG0346	lactoylglutathione lyase activity
AL538_04715	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AL538_04720	COG0668	transmembrane transport
AL538_04725	COG2261	transglycosylase associated protein
AL538_04735	COG2983	Belongs to the UPF0260 family
AL538_04745	COG2964	Protein conserved in bacteria
AL538_04755	COG0251	oxidation-reduction process
AL538_04760	COG0814	amino acid
AL538_04765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL538_04770	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AL538_04780	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AL538_04790	COG2832	Protein of unknown function (DUF454)
AL538_04795	COG0745	RESPONSE REGULATOR receiver
AL538_04800	COG0583	DNA-binding transcription factor activity
AL538_04805	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL538_04810	COG1286	toxin biosynthetic process
AL538_04815	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
AL538_04820	COG0285	dihydrofolate synthase activity
AL538_04840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL538_04845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL538_04850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL538_04870	COG3101	peptidyl-lysine hydroxylation
AL538_04875	COG2860	membrane
AL538_04885	COG2890	protein-(glutamine-N5) methyltransferase activity
AL538_04895	COG2062	phosphohistidine phosphatase, SixA
AL538_04910	COG0183	Belongs to the thiolase family
AL538_04925	COG2067	long-chain fatty acid transport protein
AL538_04935	COG2853	Lipoprotein
AL538_04940	COG3088	subunit of a heme lyase
AL538_04940	COG4235	cytochrome complex assembly
AL538_04950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL538_04955	COG1138	Cytochrome C-type biogenesis protein
AL538_04970	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL538_04975	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL538_04980	COG4133	protoheme IX ABC transporter activity
AL538_04990	COG0835	chemotaxis
AL538_05000	COG1192	Involved in chromosome partitioning
AL538_05005	COG2201	protein-glutamate methylesterase activity
AL538_05010	COG0643	Histidine kinase
AL538_05010	COG2198	Histidine kinase
AL538_05015	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AL538_05030	COG0455	bacterial-type flagellum organization
AL538_05050	COG1684	flagellar biosynthetic protein fliR
AL538_05055	COG1987	bacterial-type flagellum assembly
AL538_05110	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL538_05120	COG1677	Flagellar hook-basal body complex protein FliE
AL538_05125	COG2204	response regulator
AL538_05130	COG4191	Histidine kinase
AL538_05140	COG1516	flagellar protein fliS
AL538_05150	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL538_05155	COG1334	flagellar protein FlaG
AL538_05160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL538_05165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL538_05175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL538_05180	COG2211	Major facilitator Superfamily
AL538_05185	COG1486	melibiose metabolic process
AL538_05190	COG2169	Transcriptional regulator
AL538_05195	COG2837	iron assimilation
AL538_05220	COG1393	Belongs to the ArsC family
AL538_05245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL538_05250	COG2716	regulation of RNA biosynthetic process
AL538_05255	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL538_05270	COG4783	chaperone-mediated protein folding
AL538_05275	COG1393	Belongs to the ArsC family
AL538_05295	COG2233	PERMEase
AL538_05300	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AL538_05305	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AL538_05310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL538_05315	COG0121	glutamine amidotransferase
AL538_05320	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL538_05345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL538_05355	COG2226	methyltransferase
AL538_05365	COG1388	LysM domain
AL538_05365	COG0741	lytic transglycosylase activity
AL538_05380	COG0347	Belongs to the P(II) protein family
AL538_05400	COG0587	DNA-directed DNA polymerase activity
AL538_05425	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL538_05430	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
AL538_05440	COG0750	zinc metalloprotease
AL538_05450	COG0575	Belongs to the CDS family
AL538_05455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL538_05480	COG0024	Methionine aminopeptidase
AL538_05495	COG0564	pseudouridine synthase activity
AL538_05500	COG3098	single-species biofilm formation
AL538_05540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL538_05565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL538_05575	COG1720	tRNA m6t6A37 methyltransferase activity
AL538_05600	COG0733	neurotransmitter:sodium symporter activity
AL538_05615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL538_05620	COG0514	ATP-dependent DNA helicase (RecQ)
AL538_05625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AL538_05630	COG0745	RESPONSE REGULATOR receiver
AL538_05630	COG3706	GGDEF domain
AL538_05640	COG1477	protein flavinylation
AL538_05650	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AL538_05675	COG0271	Belongs to the BolA IbaG family
AL538_05705	COG1595	DNA-templated transcription, initiation
AL538_05720	COG3248	Nucleoside-binding outer membrane protein
AL538_05725	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AL538_05730	COG0693	protein deglycase activity
AL538_05735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AL538_05740	COG2166	iron-sulfur cluster assembly
AL538_05745	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL538_05750	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AL538_05760	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL538_05760	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL538_05770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL538_05775	COG1074	ATP-dependent DNA helicase activity
AL538_05780	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL538_05800	COG3141	response to X-ray
AL538_05815	COG2171	N-acyltransferase activity
AL538_05820	COG0584	glycerophosphoryl diester phosphodiesterase
AL538_05825	COG2271	Major facilitator Superfamily
AL538_05830	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AL538_05840	COG1349	DNA-binding transcription factor activity
AL538_05845	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AL538_05870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL538_05880	COG2017	converts alpha-aldose to the beta-anomer
AL538_05895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL538_05900	COG0768	penicillin binding
AL538_05910	COG1609	Transcriptional regulator
AL538_05915	COG3250	beta-galactosidase activity
AL538_05920	COG2731	YhcH YjgK YiaL family protein
AL538_05925	COG0531	amino acid
AL538_05930	COG0583	DNA-binding transcription factor activity
AL538_05990	COG4964	Belongs to the GSP D family
AL538_06015	COG2169	Transcriptional regulator
AL538_06020	COG1022	Amp-dependent synthetase and ligase
AL538_06030	COG0583	DNA-binding transcription factor activity
AL538_06035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL538_06040	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AL538_06050	COG0560	Phosphoserine phosphatase
AL538_06060	COG0813	purine-nucleoside phosphorylase activity
AL538_06070	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AL538_06080	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL538_06085	COG0084	hydrolase, TatD family'
AL538_06090	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL538_06095	COG3706	GGDEF domain
AL538_06115	COG3153	acetyltransferase
AL538_06140	COG0534	Mate efflux family protein
AL538_06160	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL538_06180	COG0195	Participates in both transcription termination and antitermination
AL538_06200	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL538_06210	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL538_06215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AL538_06225	COG1534	Rna-binding protein
AL538_06230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL538_06235	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AL538_06240	COG2027	D-alanyl-D-alanine carboxypeptidase
AL538_06250	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL538_06255	COG0739	heme binding
AL538_06270	COG0316	Belongs to the HesB IscA family
AL538_06280	COG0628	permease
AL538_06295	COG0784	Response regulator, receiver
AL538_06295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL538_06295	COG2205	protein histidine kinase activity
AL538_06295	COG2198	Histidine kinase
AL538_06300	COG0747	negative chemotaxis
AL538_06310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL538_06315	COG0444	Belongs to the ABC transporter superfamily
AL538_06320	COG4608	Belongs to the ABC transporter superfamily
AL538_06330	COG2971	BadF BadG BcrA BcrD
AL538_06345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL538_06350	COG3842	ATPase activity
AL538_06360	COG1840	ABC-type Fe3 transport system, periplasmic component
AL538_06365	COG0004	ammonium transporteR
AL538_06380	COG1049	propionate catabolic process, 2-methylcitrate cycle
AL538_06385	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL538_06390	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL538_06395	COG1643	Atp-dependent helicase
AL538_06405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL538_06410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL538_06420	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL538_06435	COG1560	Kdo2-lipid A biosynthetic process
AL538_06440	COG0842	Transport permease protein
AL538_06445	COG1131	(ABC) transporter
AL538_06450	COG0659	secondary active sulfate transmembrane transporter activity
AL538_06455	COG0288	reversible hydration of carbon dioxide
AL538_06470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL538_06475	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL538_06480	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AL538_06485	COG2186	Transcriptional regulator
AL538_06510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL538_06515	COG1459	type II secretion system
AL538_06525	COG0237	dephospho-CoA kinase activity
AL538_06530	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL538_06535	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AL538_06560	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL538_06565	COG4137	Cytochrome C assembly protein
AL538_06570	COG4536	flavin adenine dinucleotide binding
AL538_06590	COG0612	Peptidase, M16
AL538_06595	COG1238	metal cluster binding
AL538_06605	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AL538_06610	COG0511	ligase activity, forming carbon-carbon bonds
AL538_06610	COG5016	pyruvate
AL538_06675	COG0527	aspartate kinase activity
AL538_06690	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL538_06695	COG1546	Belongs to the CinA family
AL538_06705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL538_06735	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL538_06745	COG0148	phosphopyruvate hydratase activity
AL538_06755	COG3956	TIGRFAM MazG family protein
AL538_06760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL538_06780	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL538_06785	COG1381	Involved in DNA repair and RecF pathway recombination
AL538_06790	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL538_06800	COG0681	Belongs to the peptidase S26 family
AL538_06810	COG3086	response to oxidative stress
AL538_06825	COG1595	DNA-templated transcription, initiation
AL538_06830	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AL538_06840	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL538_06860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL538_06865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL538_06875	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
AL538_06885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AL538_06895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL538_06905	COG0583	DNA-binding transcription factor activity
AL538_06920	COG0668	transmembrane transport
AL538_06925	COG0191	fructose-bisphosphate aldolase activity
AL538_06945	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL538_06965	COG2356	endonuclease I
AL538_06970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL538_06975	COG0189	ligase activity
AL538_06980	COG1678	Uncharacterized ACR, COG1678
AL538_06985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL538_07000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL538_07005	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AL538_07010	COG0762	integral membrane protein
AL538_07025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL538_07030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL538_07130	COG1012	belongs to the aldehyde dehydrogenase family
AL538_07175	COG3437	response regulator, receiver
AL538_07190	COG1486	melibiose metabolic process
AL538_07195	COG1447	Phosphotransferase system cellobiose-specific component IIA
AL538_07205	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL538_07225	COG1028	Short-chain dehydrogenase reductase Sdr
AL538_07235	COG0795	lipopolysaccharide-transporting ATPase activity
AL538_07240	COG0795	lipopolysaccharide-transporting ATPase activity
AL538_07250	COG2927	DNA polymerase III (CHI subunit)
AL538_07255	COG0525	valine-tRNA ligase activity
AL538_07300	COG0251	oxidation-reduction process
AL538_07305	COG0204	Acyl-transferase
AL538_07315	COG5007	Belongs to the BolA IbaG family
AL538_07325	COG2854	intermembrane phospholipid transfer
AL538_07330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL538_07335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL538_07340	COG1127	ABC transporter
AL538_07350	COG0517	IMP dehydrogenase activity
AL538_07350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AL538_07360	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL538_07365	COG1137	ATPase activity
AL538_07375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL538_07380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_07390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_07395	COG2239	Acts as a magnesium transporter
AL538_07400	COG0312	modulator of DNA gyrase
AL538_07410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL538_07415	COG0564	pseudouridine synthase activity
AL538_07430	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL538_07435	COG0312	modulator of DNA gyrase
AL538_07440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AL538_07445	COG3164	Protein of unknown function
AL538_07450	COG1530	ribonuclease E activity
AL538_07455	COG0424	maF-like protein
AL538_07460	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL538_07465	COG1792	Involved in formation and maintenance of cell shape
AL538_07470	COG1077	Cell shape determining protein MreB Mrl
AL538_07515	COG1459	type II secretion system
AL538_07520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL538_07530	COG3267	Type II secretory pathway component ExeA
AL538_07530	COG3409	Peptidoglycan-binding domain 1 protein
AL538_07555	COG2200	EAL domain
AL538_07555	COG2199	diguanylate cyclase activity
AL538_07560	COG0629	single-stranded DNA binding
AL538_07575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL538_07585	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AL538_07590	COG0527	aspartate kinase activity
AL538_07595	COG0646	methionine synthase
AL538_07595	COG1410	methionine synthase
AL538_07660	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL538_07680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL538_07685	COG0735	belongs to the Fur family
AL538_07700	COG0432	Pfam Uncharacterised protein family UPF0047
AL538_07710	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL538_07715	COG0305	Participates in initiation and elongation during chromosome replication
AL538_07740	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL538_07745	COG0338	D12 class N6 adenine-specific DNA methyltransferase
AL538_07790	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AL538_07800	COG0678	peroxiredoxin activity
AL538_07800	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL538_07805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL538_07815	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL538_07815	COG0165	Argininosuccinate lyase
AL538_07830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL538_07840	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL538_07850	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL538_07855	COG0460	homoserine dehydrogenase
AL538_07855	COG0527	aspartate kinase activity
AL538_07860	COG0626	cystathionine gamma-synthase activity
AL538_07870	COG0281	malic enzyme
AL538_07880	COG2906	2 iron, 2 sulfur cluster binding
AL538_07890	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL538_07905	COG2168	tRNA wobble position uridine thiolation
AL538_07910	COG2923	Belongs to the DsrF TusC family
AL538_07915	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL538_07920	COG2964	Protein conserved in bacteria
AL538_07925	COG0545	Peptidyl-prolyl cis-trans isomerase
AL538_07940	COG1446	asparaginase
AL538_07945	COG1047	Peptidyl-prolyl cis-trans
AL538_07960	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL538_07965	COG0488	(ABC) transporter
AL538_07975	COG0429	hydrolase of the alpha beta-hydrolase fold
AL538_07985	COG3954	Phosphoribulokinase
AL538_07990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL538_08010	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL538_08040	COG0546	phosphoglycolate phosphatase activity
AL538_08045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL538_08050	COG0557	exoribonuclease II activity
AL538_08060	COG1017	nitric oxide dioxygenase activity
AL538_08060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL538_08065	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
AL538_08070	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL538_08075	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
AL538_08080	COG0330	HflC and HflK could
AL538_08085	COG0330	HflC and HflK could
AL538_08090	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL538_08105	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL538_08115	COG0802	atpase or kinase
AL538_08120	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AL538_08190	COG1162	GTPase activity
AL538_08200	COG0471	metal ion transport
AL538_08205	COG0840	transmembrane signaling receptor activity
AL538_08215	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AL538_08220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL538_08225	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL538_08235	COG1045	serine acetyltransferase
AL538_08240	COG4942	peptidase
AL538_08265	COG1053	succinate dehydrogenase
AL538_08270	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL538_08300	COG1509	lysine 2,3-aminomutase activity
AL538_08350	COG0534	Mate efflux family protein
AL538_08360	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AL538_08365	COG3678	ATP-independent chaperone mediated protein folding
AL538_08370	COG0745	RESPONSE REGULATOR receiver
AL538_08375	COG2205	protein histidine kinase activity
AL538_08380	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL538_08385	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AL538_08390	COG3030	protein affecting phage T7 exclusion by the F plasmid
AL538_08395	COG1027	Aspartate ammonia-lyase
AL538_08400	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL538_08405	COG4232	protein-disulfide reductase activity
AL538_08415	COG2095	MarC family integral membrane protein
AL538_08425	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL538_08445	COG2205	protein histidine kinase activity
AL538_08445	COG0784	Response regulator, receiver
AL538_08445	COG2198	Histidine kinase
AL538_08450	COG2814	Major facilitator Superfamily
AL538_08465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL538_08470	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL538_08475	COG0511	ligase activity, forming carbon-carbon bonds
AL538_08480	COG0439	Biotin carboxylase
AL538_08490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL538_08495	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AL538_08500	COG3300	MHYT domain
AL538_08500	COG5001	Diguanylate cyclase
AL538_08555	COG1982	Orn Lys Arg decarboxylase major
AL538_08560	COG0531	amino acid
AL538_08570	COG3710	Transcriptional regulator
AL538_08575	COG0789	Transcriptional regulator
AL538_08590	COG0151	Belongs to the GarS family
AL538_08605	COG1253	flavin adenine dinucleotide binding
AL538_08610	COG3068	Protein conserved in bacteria
AL538_08620	COG1573	uracil-dna glycosylase
AL538_08640	COG2816	NAD+ diphosphatase activity
AL538_08645	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
AL538_08665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL538_08680	COG0250	Participates in transcription elongation, termination and antitermination
AL538_08685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL538_08725	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL538_08735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL538_08880	COG3339	Conserved Protein
AL538_08895	COG2003	Belongs to the UPF0758 family
AL538_08915	COG0582	viral genome integration into host DNA
AL538_08935	COG0534	Mate efflux family protein
AL538_08950	COG2937	Belongs to the GPAT DAPAT family
AL538_08960	COG3161	chorismate lyase activity
AL538_08965	COG1580	Controls the rotational direction of flagella during chemotaxis
AL538_08970	COG0705	Rhomboid family
AL538_08985	COG2177	Part of the ABC transporter FtsEX involved in
AL538_08990	COG2884	Cell division ATP-binding protein ftsE
AL538_08995	COG0552	protein localization to endoplasmic reticulum
AL538_09000	COG0742	ribosomal rna small subunit methyltransferase
AL538_09010	COG2095	MarC family integral membrane protein
AL538_09055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL538_09060	COG0640	Transcriptional regulator
AL538_09065	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL538_09070	COG1280	lysine exporter protein (LysE YggA)
AL538_09075	COG2267	carboxylic ester hydrolase activity
AL538_09080	COG0561	phosphatase activity
AL538_09100	COG2199	diguanylate cyclase activity
AL538_09100	COG3287	FIST C domain
AL538_09100	COG2200	EAL domain
AL538_09105	COG1011	Hydrolase
AL538_09125	COG0019	diaminopimelate decarboxylase activity
AL538_09140	COG3072	Adenylate cyclase
AL538_09150	COG1587	Uroporphyrinogen-III synthase
AL538_09155	COG2959	enzyme of heme biosynthesis
AL538_09160	COG3071	HemY protein
AL538_09200	COG0633	Ferredoxin
AL538_09205	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL538_09215	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL538_09220	COG3118	belongs to the thioredoxin family
AL538_09235	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL538_09245	COG0514	ATP-dependent DNA helicase (RecQ)
AL538_09250	COG2962	Rard protein
AL538_09260	COG1280	lysine exporter protein (LysE YggA)
AL538_09265	COG0405	Gamma-glutamyltransferase
AL538_09275	COG0210	DNA helicase
AL538_09285	COG3220	belongs to the UPF0276 family
AL538_09305	COG2814	Major facilitator Superfamily
AL538_09315	COG0006	proline dipeptidase activity
AL538_09315	COG0006	proline dipeptidase activity
AL538_09330	COG2104	thiamine diphosphate biosynthetic process
AL538_09335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL538_09355	COG2132	Multicopper oxidase
AL538_09400	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL538_09410	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL538_09425	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL538_09430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL538_09435	COG0551	DNA topoisomerase type I activity
AL538_09445	COG0758	DNA mediated transformation
AL538_09455	COG0242	peptide deformylase activity
AL538_09465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL538_09465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL538_09470	COG0569	domain protein
AL538_09475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL538_09485	COG1272	protein, Hemolysin III
AL538_09490	COG4326	sporulation control protein
AL538_09495	COG3084	Protein conserved in bacteria
AL538_09505	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AL538_09510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL538_09515	COG0204	Acyl-transferase
AL538_09525	COG3706	GGDEF domain
AL538_09530	COG0606	chelatase, subunit chli
AL538_09540	COG3978	acetolactate synthase activity
AL538_09545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL538_09550	COG0129	dihydroxy-acid dehydratase activity
AL538_09560	COG0583	DNA-binding transcription factor activity
AL538_09565	COG2814	Major facilitator Superfamily
AL538_09575	COG0765	amino acid transport
AL538_09585	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL538_09595	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL538_09620	COG0356	it plays a direct role in the translocation of protons across the membrane
AL538_09625	COG3312	ion transport
AL538_09630	COG1475	DNA binding
AL538_09635	COG1192	Involved in chromosome partitioning
AL538_09645	COG0445	tRNA wobble uridine modification
AL538_09650	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL538_09675	COG1126	abc transporter atp-binding protein
AL538_09695	COG0592	DNA-directed DNA polymerase activity
AL538_09705	COG0187	DNA topoisomerase II activity
AL538_09710	COG0071	Belongs to the small heat shock protein (HSP20) family
AL538_09715	COG3977	Valine--pyruvate aminotransferase
AL538_09720	COG0366	Alpha amylase catalytic
AL538_09735	COG2119	membrane
AL538_09745	COG0425	Belongs to the sulfur carrier protein TusA family
AL538_09760	COG0604	alcohol dehydrogenase
AL538_09765	COG0183	Belongs to the thiolase family
AL538_09775	COG1739	Uncharacterized protein family UPF0029
AL538_09780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL538_09825	COG0583	DNA-binding transcription factor activity
AL538_09830	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL538_09835	COG2960	long-chain fatty acid transporting porin activity
AL538_09840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL538_09845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL538_09850	COG1309	transcriptional regulator
AL538_09900	COG4172	Belongs to the ABC transporter superfamily
AL538_09905	COG0747	negative chemotaxis
AL538_09915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AL538_09950	COG1609	Transcriptional regulator
AL538_09955	COG0583	DNA-binding transcription factor activity
AL538_09960	COG2076	Multidrug Resistance protein
AL538_09975	COG0129	dihydroxy-acid dehydratase activity
AL538_09980	COG3265	gluconokinase activity
AL538_09985	COG2610	gluconate transmembrane transporter activity
AL538_09990	COG0800	Aldolase
AL538_09995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL538_10010	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL538_10025	COG1522	sequence-specific DNA binding
AL538_10030	COG5002	protein histidine kinase activity
AL538_10030	COG5001	Diguanylate cyclase
AL538_10045	COG0697	spore germination
AL538_10050	COG0589	response to stress
AL538_10060	COG1528	Iron-storage protein
AL538_10070	COG2081	HI0933 family
AL538_10085	COG1322	Protein conserved in bacteria
AL538_10095	COG3165	ubiquinone biosynthetic process from chorismate
AL538_10115	COG0805	protein transport
AL538_10120	COG0084	hydrolase, TatD family'
AL538_10135	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL538_10135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL538_10140	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL538_10165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL538_10170	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL538_10180	COG2204	response regulator
AL538_10185	COG3852	Histidine kinase
AL538_10195	COG0174	glutamine synthetase
AL538_10220	COG1490	D-aminoacyl-tRNA deacylase activity
AL538_10225	COG0456	acetyltransferase
AL538_10245	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL538_10250	COG3031	protein transport across the cell outer membrane
AL538_10260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL538_10265	COG1459	type II secretion system
AL538_10270	COG2165	general secretion pathway protein
AL538_10275	COG2165	general secretion pathway protein
AL538_10280	COG2165	general secretion pathway protein
AL538_10285	COG4795	General secretion pathway protein
AL538_10290	COG3156	type II secretion system protein K
AL538_10295	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL538_10300	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
AL538_10310	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL538_10315	COG0494	nUDIX hydrolase
AL538_10325	COG1040	competence protein
AL538_10340	COG2183	response to ionizing radiation
AL538_10350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL538_10355	COG0745	RESPONSE REGULATOR receiver
AL538_10360	COG2205	protein histidine kinase activity
AL538_10365	COG2233	PERMEase
AL538_10375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL538_10380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL538_10385	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL538_10390	COG1758	RNA polymerase activity
AL538_10395	COG0194	GDP metabolic process
AL538_10410	COG0848	biopolymer transport protein
AL538_10415	COG0811	peptide transport
AL538_10435	COG4174	ABC transporter (Permease)
AL538_10440	COG4239	(ABC) transporter, permease
AL538_10445	COG0747	negative chemotaxis
AL538_10450	COG0444	Belongs to the ABC transporter superfamily
AL538_10455	COG4608	Belongs to the ABC transporter superfamily
AL538_10480	COG0745	RESPONSE REGULATOR receiver
AL538_10485	COG1561	YicC-like family, N-terminal region
AL538_10490	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL538_10500	COG1560	Kdo2-lipid A biosynthetic process
AL538_10510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL538_10515	COG0840	transmembrane signaling receptor activity
AL538_10535	COG2194	sulfuric ester hydrolase activity
AL538_10550	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL538_10565	COG0463	Glycosyl transferase, family 2
AL538_10570	COG0859	PFAM glycosyl transferase family 9
AL538_10575	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL538_10580	COG3642	lipopolysaccharide core region biosynthetic process
AL538_10590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AL538_10620	COG1519	Transferase
AL538_10625	COG0859	PFAM glycosyl transferase family 9
AL538_10635	COG1560	Kdo2-lipid A biosynthetic process
AL538_10645	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL538_10685	COG4750	Nucleotidyl transferase
AL538_10695	COG3475	LICD family
AL538_10705	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AL538_10730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL538_10740	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AL538_10745	COG0149	triose-phosphate isomerase activity
AL538_10770	COG1494	fructose-1,6-bisphosphatase
AL538_10780	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL538_10785	COG1575	Belongs to the MenA family. Type 1 subfamily
AL538_10805	COG1609	Transcriptional regulator
AL538_10810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL538_10815	COG0254	rRNA binding
AL538_10830	COG0088	Forms part of the polypeptide exit tunnel
AL538_10850	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AL538_10900	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL538_10915	COG1841	ribosomal large subunit assembly
AL538_10920	COG0200	Binds to the 23S rRNA
AL538_10925	COG0201	protein transport
AL538_10935	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL538_10940	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL538_10950	COG0202	RNA polymerase activity
AL538_10955	COG0203	ribosomal protein L17
AL538_10965	COG0545	Peptidyl-prolyl cis-trans isomerase
AL538_10980	COG2153	protein acetylation
AL538_10985	COG0513	Belongs to the DEAD box helicase family
AL538_10995	COG0737	Belongs to the 5'-nucleotidase family
AL538_11000	COG1648	precorrin-2 dehydrogenase activity
AL538_11000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL538_11015	COG0471	metal ion transport
AL538_11015	COG3273	potassium ion transport
AL538_11020	COG0529	Catalyzes the synthesis of activated sulfate
AL538_11040	COG1136	(ABC) transporter
AL538_11050	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
AL538_11060	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL538_11065	COG0729	surface antigen
AL538_11075	COG2105	PFAM AIG2 family protein
AL538_11085	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL538_11095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL538_11100	COG0163	prenyltransferase activity
AL538_11105	COG4143	(ABC) transporter
AL538_11110	COG1178	ABC-type Fe3 transport system permease component
AL538_11115	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AL538_11150	COG0142	geranyltranstransferase activity
AL538_11155	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL538_11165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL538_11170	COG2966	Psort location CytoplasmicMembrane, score
AL538_11175	COG3610	response to peptide
AL538_11195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL538_11200	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL538_11205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL538_11210	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL538_11215	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AL538_11235	COG0473	3-isopropylmalate dehydrogenase activity
AL538_11240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL538_11250	COG0671	phosphoesterase, PA-phosphatase related
AL538_11260	COG0583	DNA-binding transcription factor activity
AL538_11265	COG1022	Amp-dependent synthetase and ligase
AL538_11270	COG0028	Belongs to the TPP enzyme family
AL538_11275	COG0440	acetolactate synthase activity
AL538_11280	COG3706	GGDEF domain
AL538_11290	COG0469	pyruvate kinase activity
AL538_11295	COG1349	DNA-binding transcription factor activity
AL538_11300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL538_11320	COG5002	protein histidine kinase activity
AL538_11325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL538_11330	COG3722	fumarate hydratase activity
AL538_11340	COG2213	PTS system mannitol-specific
AL538_11340	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_11370	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AL538_11375	COG0358	DNA primase activity
AL538_11380	COG1610	YqeY-like protein
AL538_11385	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AL538_11390	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL538_11395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL538_11405	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL538_11410	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL538_11425	COG3409	Peptidoglycan-binding domain 1 protein
AL538_11425	COG3267	Type II secretory pathway component ExeA
AL538_11435	COG4991	sh3 domain protein
AL538_11440	COG0306	phosphate transporter
AL538_11445	COG1392	Phosphate transport regulator
AL538_11450	COG3025	triphosphatase activity
AL538_11455	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL538_11465	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL538_11475	COG1538	Outer membrane efflux protein
AL538_11480	COG0494	nUDIX hydrolase
AL538_11485	COG3151	Protein conserved in bacteria
AL538_11495	COG3150	esterase
AL538_11500	COG0187	DNA topoisomerase II activity
AL538_11505	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AL538_11510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL538_11525	COG3105	Protein conserved in bacteria
AL538_11530	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL538_11545	COG0723	plastoquinol--plastocyanin reductase activity
AL538_11550	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL538_11555	COG2857	Cytochrome c1
AL538_11560	COG0625	glutathione transferase activity
AL538_11565	COG2969	positive regulation of protein catabolic process
AL538_11570	COG2823	Periplasmic or secreted lipoprotein
AL538_11575	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL538_11590	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL538_11605	COG3116	cell division
AL538_11610	COG0768	penicillin binding
AL538_11615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL538_11620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL538_11635	COG0772	Belongs to the SEDS family
AL538_11650	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL538_11655	COG0849	cell division
AL538_11660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AL538_11675	COG0494	nUDIX hydrolase
AL538_11685	COG0505	Belongs to the CarA family
AL538_11690	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL538_11710	COG0730	response to heat
AL538_11715	COG0583	DNA-binding transcription factor activity
AL538_11720	COG2860	membrane
AL538_11745	COG0493	'glutamate synthase
AL538_11750	COG0070	glutamate synthase
AL538_11750	COG0067	glutamate synthase
AL538_11750	COG0069	glutamate synthase activity
AL538_11760	COG0067	glutamate synthase
AL538_11760	COG0070	glutamate synthase
AL538_11760	COG0069	glutamate synthase activity
AL538_11765	COG1242	4 iron, 4 sulfur cluster binding
AL538_11770	COG2203	Gaf domain
AL538_11770	COG3706	GGDEF domain
AL538_11770	COG4251	negative regulation of phosphorylation
AL538_11770	COG5001	Diguanylate cyclase
AL538_11780	COG5002	protein histidine kinase activity
AL538_11780	COG0784	Response regulator, receiver
AL538_11780	COG2198	Histidine kinase
AL538_11790	COG0745	RESPONSE REGULATOR receiver
AL538_11800	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL538_11815	COG0083	homoserine kinase activity
AL538_11820	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL538_11825	COG0431	NADPH-dependent FMN reductase
AL538_11855	COG1115	amino acid carrier protein
AL538_11860	COG3022	response to hydroperoxide
AL538_11870	COG0513	Belongs to the DEAD box helicase family
AL538_11885	COG0716	FMN binding
AL538_11895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL538_11900	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL538_11925	COG0667	Aldo Keto reductase
AL538_11945	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
AL538_11950	COG0730	response to heat
AL538_11965	COG1283	sodium-dependent phosphate transmembrane transporter activity
AL538_11970	COG0583	DNA-binding transcription factor activity
AL538_11975	COG0640	Transcriptional regulator
AL538_11980	COG0268	Binds directly to 16S ribosomal RNA
AL538_11985	COG0728	peptidoglycan biosynthetic process
AL538_11990	COG0196	riboflavin kinase activity
AL538_12005	COG1047	Peptidyl-prolyl cis-trans
AL538_12010	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL538_12015	COG3279	Response regulator of the LytR AlgR family
AL538_12020	COG3275	phosphorelay sensor kinase activity
AL538_12025	COG1966	Carbon starvation protein
AL538_12045	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL538_12050	COG1472	Belongs to the glycosyl hydrolase 3 family
AL538_12055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL538_12060	COG1605	Chorismate mutase
AL538_12060	COG0287	Prephenate dehydrogenase
AL538_12065	COG0739	heme binding
AL538_12075	COG0488	(ABC) transporter
AL538_12090	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AL538_12095	COG0077	Prephenate dehydratase
AL538_12095	COG1605	Chorismate mutase
AL538_12100	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AL538_12105	COG0741	lytic transglycosylase activity
AL538_12110	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL538_12115	COG0564	pseudouridine synthase activity
AL538_12125	COG0542	response to heat
AL538_12170	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AL538_12180	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL538_12195	COG0745	RESPONSE REGULATOR receiver
AL538_12200	COG5002	protein histidine kinase activity
AL538_12210	COG0248	Ppx GppA phosphatase
AL538_12215	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AL538_12220	COG0573	inorganic phosphate transmembrane transporter activity
AL538_12225	COG0581	inorganic phosphate transmembrane transporter activity
AL538_12230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL538_12235	COG0704	Plays a role in the regulation of phosphate uptake
AL538_12265	COG0450	alkyl hydroperoxide reductase
AL538_12270	COG0583	DNA-binding transcription factor activity
AL538_12275	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL538_12285	COG0517	IMP dehydrogenase activity
AL538_12310	COG1862	Preprotein translocase
AL538_12315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL538_12320	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL538_12335	COG0483	inositol monophosphate 1-phosphatase activity
AL538_12340	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AL538_12355	COG0822	iron-sulfur transferase activity
AL538_12360	COG0316	Belongs to the HesB IscA family
AL538_12375	COG0633	Ferredoxin
AL538_12380	COG2975	iron-sulfur cluster assembly
AL538_12415	COG2976	Protein conserved in bacteria
AL538_12420	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL538_12435	COG2199	diguanylate cyclase activity
AL538_12435	COG2203	Gaf domain
AL538_12445	COG0516	GMP reductase activity
AL538_12445	COG0517	IMP dehydrogenase activity
AL538_12455	COG1757	Na H antiporter
AL538_12465	COG1584	GPR1 FUN34 yaaH family protein
AL538_12470	COG1115	amino acid carrier protein
AL538_12480	COG0583	DNA-binding transcription factor activity
AL538_12495	COG2873	o-acetylhomoserine
AL538_12500	COG0316	Belongs to the HesB IscA family
AL538_12505	COG0719	Fe-S assembly protein
AL538_12510	COG0396	ATPase activity
AL538_12515	COG0719	Fe-S assembly protein
AL538_12535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL538_12555	COG1289	transmembrane transporter activity
AL538_12560	COG0583	DNA-binding transcription factor activity
AL538_12615	COG2003	Belongs to the UPF0758 family
AL538_12675	COG0582	viral genome integration into host DNA
AL538_12690	COG2867	negative regulation of translational initiation
AL538_12695	COG2914	Belongs to the UPF0125 (RnfH) family
AL538_12700	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL538_12705	COG0497	DNA recombination
AL538_12725	COG1301	dicarboxylic acid transport
AL538_12765	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
AL538_12770	COG0590	tRNA wobble adenosine to inosine editing
AL538_12780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL538_12780	COG0047	phosphoribosylformylglycinamidine synthase activity
AL538_12810	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL538_12815	COG2252	PERMEase
AL538_12820	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AL538_12840	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL538_12845	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL538_12850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL538_12850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL538_12875	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AL538_12880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AL538_12890	COG0142	geranyltranstransferase activity
AL538_12900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL538_12915	COG0583	DNA-binding transcription factor activity
AL538_12925	COG2363	Small membrane protein
AL538_12945	COG1611	Belongs to the LOG family
AL538_12950	COG3706	GGDEF domain
AL538_12970	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
AL538_12975	COG0737	Belongs to the 5'-nucleotidase family
AL538_12985	COG1464	Belongs to the NlpA lipoprotein family
AL538_12990	COG2011	ABC-type metal ion transport system permease component
AL538_12995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AL538_13000	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL538_13010	COG1263	PTS System
AL538_13010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL538_13015	COG0366	Alpha amylase catalytic
AL538_13030	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL538_13035	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL538_13055	COG1686	Belongs to the peptidase S11 family
AL538_13060	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL538_13065	COG0772	Belongs to the SEDS family
AL538_13070	COG0768	penicillin binding
AL538_13080	COG0799	negative regulation of ribosome biogenesis
AL538_13085	COG1466	dna polymerase III delta subunit
AL538_13090	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
AL538_13100	COG2888	peptidyl-tyrosine sulfation
AL538_13105	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL538_13110	COG4535	Mg2 and Co2 transporter CorC
AL538_13120	COG1702	phosphate starvation-inducible protein PhoH
AL538_13130	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL538_13250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL538_13275	COG2890	protein-(glutamine-N5) methyltransferase activity
AL538_13280	COG3094	Invasion gene expression up-regulator, SirB
AL538_13285	COG2912	Transglutaminase-like superfamily
AL538_13290	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL538_13295	COG0737	Belongs to the 5'-nucleotidase family
AL538_13300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL538_13305	COG1187	pseudouridine synthase activity
AL538_13310	COG2840	Smr protein MutS2
AL538_13350	COG2608	mercury ion transmembrane transporter activity
AL538_13350	COG2217	Heavy metal translocating P-type atpase
AL538_13360	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL538_13425	COG0835	chemotaxis
AL538_13425	COG0784	Response regulator, receiver
AL538_13430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL538_13435	COG1815	bacterial-type flagellum-dependent cell motility
AL538_13440	COG1558	bacterial-type flagellum-dependent cell motility
AL538_13445	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL538_13450	COG1749	Flagellar hook protein flgE
AL538_13455	COG4787	bacterial-type flagellum-dependent cell motility
AL538_13460	COG4786	Flagellar basal body rod
AL538_13465	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL538_13470	COG1706	bacterial-type flagellum-dependent cell motility
AL538_13475	COG1705	Flagellar rod assembly protein muramidase FlgJ
AL538_13475	COG3951	Flagellar rod assembly protein muramidase FlgJ
AL538_13490	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL538_13495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL538_13500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL538_13505	COG2190	(PTS) system
AL538_13510	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL538_13515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_13520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AL538_13525	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
AL538_13555	COG0330	HflC and HflK could
AL538_13560	COG3118	belongs to the thioredoxin family
AL538_13565	COG0300	oxidoreductase activity
AL538_13570	COG1090	epimerase
AL538_13600	COG0622	Phosphoesterase
AL538_13620	COG3710	Transcriptional regulator
AL538_13635	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL538_13640	COG3104	oligopeptide transport
AL538_13650	COG0367	asparagine synthase
AL538_13655	COG4651	solute:proton antiporter activity
AL538_13655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL538_13660	COG1846	Transcriptional regulator
AL538_13660	COG1940	carbohydrate kinase activity
AL538_13665	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
AL538_13670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL538_13670	COG1263	PTS System
AL538_13670	COG2190	(PTS) system
AL538_13685	COG0735	belongs to the Fur family
AL538_13695	COG0716	FMN binding
AL538_13705	COG0596	Alpha beta hydrolase
AL538_13715	COG0033	Phosphoglucomutase
AL538_13730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AL538_13740	COG2009	succinate dehydrogenase
AL538_13745	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL538_13750	COG1053	succinate dehydrogenase
AL538_13760	COG0567	Dehydrogenase, E1 component
AL538_13765	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL538_13780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL538_13785	COG1121	(ABC) transporter
AL538_13790	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
AL538_13795	COG4977	sequence-specific DNA binding
AL538_13800	COG1918	ferrous iron import across plasma membrane
AL538_13830	COG3102	Protein conserved in bacteria
AL538_13835	COG0788	formyltetrahydrofolate deformylase activity
AL538_13840	COG1199	ATP-dependent helicase activity
AL538_13845	COG1214	PFAM Peptidase M22, glycoprotease
AL538_13855	COG3065	identical protein binding
AL538_13860	COG2267	carboxylic ester hydrolase activity
AL538_13865	COG0318	PFAM AMP-dependent synthetase and ligase
AL538_13870	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AL538_13875	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL538_13880	COG2894	cell division
AL538_13895	COG2951	lytic endotransglycosylase activity
AL538_13905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL538_13965	COG1715	Restriction endonuclease
AL538_13970	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL538_14035	COG1028	Short-chain dehydrogenase reductase Sdr
AL538_14040	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL538_14070	COG2986	histidine ammonia-lyase
AL538_14075	COG1216	Glycosyl transferase, family 2
AL538_14095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL538_14100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL538_14140	COG1028	Short-chain dehydrogenase reductase Sdr
AL538_14150	COG1169	isochorismate synthase
AL538_14155	COG1021	2,3-dihydroxybenzoate-AMP ligase
AL538_14160	COG3433	isochorismatase activity
AL538_14160	COG1535	isochorismatase
AL538_14165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL538_14165	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AL538_14180	COG4771	TonB-dependent receptor
AL538_14185	COG1253	flavin adenine dinucleotide binding
AL538_14190	COG0513	Belongs to the DEAD box helicase family
AL538_14195	COG0569	domain protein
AL538_14200	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL538_14215	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AL538_14220	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL538_14225	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL538_14240	COG4191	Histidine kinase
AL538_14260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL538_14265	COG0776	regulation of translation
AL538_14270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL538_14295	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
AL538_14300	COG0436	Aminotransferase
AL538_14305	COG1169	isochorismate synthase
AL538_14315	COG0596	Alpha beta hydrolase
AL538_14320	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AL538_14325	COG1441	menaquinone biosynthetic process
AL538_14335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL538_14335	COG1263	PTS System
AL538_14335	COG2190	(PTS) system
AL538_14340	COG0583	DNA-binding transcription factor activity
AL538_14350	COG2855	membrane
AL538_14355	COG0477	Major facilitator Superfamily
AL538_14405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL538_14430	COG1522	sequence-specific DNA binding
AL538_14440	COG3385	transposase activity
AL538_14445	COG1946	Acyl-CoA thioesterase
AL538_14450	COG3126	Type III secretion system lipoprotein chaperone (YscW)
AL538_14465	COG3706	GGDEF domain
AL538_14475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AL538_14480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL538_14485	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL538_14490	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AL538_14495	COG0517	IMP dehydrogenase activity
AL538_14495	COG0516	GMP reductase activity
AL538_14505	COG2217	Heavy metal translocating P-type atpase
AL538_14525	COG0537	adenosine 5'-monophosphoramidase activity
AL538_14555	COG1252	NADH dehydrogenase
AL538_14570	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL538_14580	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL538_14585	COG1136	(ABC) transporter
AL538_14590	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL538_14605	COG1132	(ABC) transporter
AL538_14625	COG2719	SpoVR family
AL538_14630	COG2718	Belongs to the UPF0229 family
AL538_14635	COG2766	serine protein kinase
AL538_14650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL538_14660	COG1882	Formate acetyltransferase
AL538_14685	COG4215	(ABC) transporter
AL538_14695	COG0708	Exodeoxyribonuclease III
AL538_14700	COG0840	transmembrane signaling receptor activity
AL538_14715	COG0730	response to heat
AL538_14720	COG1199	ATP-dependent helicase activity
AL538_14730	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL538_14735	COG1187	pseudouridine synthase activity
AL538_14745	COG1278	Cold shock
AL538_14755	COG0542	response to heat
AL538_14760	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL538_14790	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AL538_14795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL538_14800	COG0297	glycogen (starch) synthase activity
AL538_14820	COG3070	regulator of competence-specific genes
AL538_14835	COG0745	RESPONSE REGULATOR receiver
AL538_14840	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL538_14845	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL538_14855	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
AL538_14860	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
AL538_14875	COG0189	ligase activity
AL538_14875	COG4067	protein conserved in archaea
AL538_14890	COG1801	Protein of unknown function DUF72
AL538_14905	COG0840	transmembrane signaling receptor activity
AL538_14910	COG0632	four-way junction helicase activity
AL538_14920	COG1271	oxidase subunit
AL538_14925	COG1294	oxidase, subunit
AL538_14930	COG4890	Cyd operon protein YbgT
AL538_14940	COG0824	Thioesterase
AL538_14945	COG0811	peptide transport
AL538_14960	COG0823	Involved in the tonB-independent uptake of proteins
AL538_14965	COG2885	chlorophyll binding
AL538_14970	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AL538_14985	COG0673	inositol 2-dehydrogenase activity
AL538_14990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL538_14990	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_14990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_14995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_15000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_15010	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL538_15020	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL538_15025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_15030	COG2207	Transcriptional regulator
AL538_15035	COG0371	Dehydrogenase
AL538_15040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL538_15060	COG3766	membrane
AL538_15070	COG0754	glutathionylspermidine amidase activity
AL538_15080	COG0784	Response regulator, receiver
AL538_15080	COG5002	protein histidine kinase activity
AL538_15160	COG4669	(LipO)protein
AL538_15205	COG4792	protein secretion
AL538_15210	COG4791	protein targeting
AL538_15215	COG4794	Type iii secretion
AL538_15220	COG4790	Type iii secretion
AL538_15225	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL538_15290	COG0457	Tetratricopeptide repeat
AL538_15305	COG0789	Transcriptional regulator
AL538_15310	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AL538_15325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL538_15325	COG1263	PTS System
AL538_15330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL538_15335	COG1621	beta-fructofuranosidase activity
AL538_15340	COG2824	Alkylphosphonate utilization operon protein PhnA
AL538_15355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL538_15380	COG0534	Mate efflux family protein
AL538_15385	COG0444	Belongs to the ABC transporter superfamily
AL538_15390	COG4608	Belongs to the ABC transporter superfamily
AL538_15395	COG0747	negative chemotaxis
AL538_15415	COG0583	DNA-binding transcription factor activity
AL538_15420	COG4771	TonB-dependent receptor
AL538_15440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL538_15445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL538_15455	COG2186	Transcriptional regulator
AL538_15465	COG1288	antiporter activity
AL538_15490	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL538_15505	COG2176	DNA-directed DNA polymerase activity
AL538_15510	COG0517	IMP dehydrogenase activity
AL538_15515	COG2186	Transcriptional regulator
AL538_15520	COG1028	Short-chain dehydrogenase reductase Sdr
AL538_15525	COG2186	Transcriptional regulator
AL538_15545	COG1917	Cupin 2, conserved barrel domain protein
AL538_15550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL538_15555	COG0800	Aldolase
AL538_15560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL538_15570	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AL538_15600	COG3568	Endonuclease Exonuclease Phosphatase
AL538_15610	COG4934	collagen metabolic process
AL538_15645	COG0686	Belongs to the AlaDH PNT family
AL538_15655	COG1674	ftsk spoiiie
AL538_15665	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AL538_15685	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL538_15690	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AL538_15725	COG0300	oxidoreductase activity
AL538_15740	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL538_15750	COG2268	Band 7 protein
AL538_15760	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AL538_15770	COG0482	sulfurtransferase activity
AL538_15780	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL538_15790	COG1757	Na H antiporter
AL538_15805	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL538_15810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL538_15815	COG0131	Imidazoleglycerol-phosphate dehydratase
AL538_15815	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL538_15820	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL538_15825	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL538_15830	COG0107	imidazoleglycerol-phosphate synthase activity
AL538_15835	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL538_15835	COG0140	phosphoribosyl-ATP diphosphatase activity
AL538_15840	COG3012	SEC-C Motif Domain Protein
AL538_15845	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AL538_15850	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL538_15855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL538_15860	COG0215	cysteine-tRNA ligase activity
AL538_15865	COG1435	thymidine kinase activity
AL538_15870	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AL538_15895	COG2116	formate transmembrane transporter activity
AL538_15900	COG0390	transport system, permease component
AL538_15905	COG4459	periplasmic nitrate reductase
AL538_15910	COG3005	denitrification pathway
AL538_15915	COG0243	molybdopterin cofactor binding
AL538_15930	COG1121	(ABC) transporter
AL538_15935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL538_15940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL538_15945	COG1227	inorganic diphosphatase activity
AL538_15955	COG4172	Belongs to the ABC transporter superfamily
AL538_15965	COG4171	peptide transport system, permease
AL538_15970	COG4168	peptide transport system, permease
AL538_15980	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
AL538_15985	COG1842	Phage shock protein A
AL538_16015	COG2818	Glycosylase
AL538_16020	COG5380	lipid catabolic process
AL538_16025	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
AL538_16030	COG0626	cystathionine gamma-synthase activity
AL538_16040	COG0733	neurotransmitter:sodium symporter activity
AL538_16050	COG0564	pseudouridine synthase activity
AL538_16060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL538_16065	COG1151	hydroxylamine reductase activity
AL538_16070	COG3604	Transcriptional regulator
AL538_16075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AL538_16080	COG4136	ATPase activity
AL538_16085	COG4135	transport system, permease component
AL538_16090	COG4134	Bacterial extracellular solute-binding protein
AL538_16095	COG0398	Pfam SNARE associated Golgi protein
AL538_16105	COG0493	'glutamate synthase
AL538_16130	COG0659	secondary active sulfate transmembrane transporter activity
AL538_16140	COG3313	Fe-S protein
AL538_16180	COG2205	protein histidine kinase activity
AL538_16195	COG1061	Type III restriction enzyme res subunit
AL538_16200	COG1187	pseudouridine synthase activity
AL538_16205	COG2814	Major facilitator Superfamily
AL538_16215	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL538_16225	COG1609	Transcriptional regulator
AL538_16230	COG0702	epimerase
AL538_16235	COG0534	Mate efflux family protein
AL538_16240	COG4181	ATPase activity
AL538_16270	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL538_16280	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AL538_16290	COG1737	Transcriptional regulator
AL538_16295	COG0076	glutamate decarboxylase activity
AL538_16305	COG2431	L-lysine efflux transmembrane transporter activity
AL538_16315	COG3070	regulator of competence-specific genes
AL538_16330	COG4191	Histidine kinase
AL538_16330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL538_16340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL538_16350	COG5002	protein histidine kinase activity
AL538_16350	COG5001	Diguanylate cyclase
AL538_16350	COG3447	MASE1 domain protein
AL538_16370	COG0583	DNA-binding transcription factor activity
AL538_16375	COG2610	gluconate transmembrane transporter activity
AL538_16385	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
AL538_16390	COG4988	ABC transporter
AL538_16395	COG0492	ferredoxin-NADP+ reductase activity
AL538_16415	COG3706	GGDEF domain
AL538_16420	COG0471	metal ion transport
AL538_16425	COG2949	membrane
AL538_16435	COG1643	Atp-dependent helicase
AL538_16475	COG0471	metal ion transport
AL538_16480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL538_16480	COG4191	Histidine kinase
AL538_16490	COG5001	Diguanylate cyclase
AL538_16490	COG3300	MHYT domain
AL538_16500	COG1280	lysine exporter protein (LysE YggA)
AL538_16505	COG1328	CTP reductase activity
AL538_16510	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL538_16520	COG0861	Integral membrane protein TerC family
AL538_16530	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL538_16540	COG3706	GGDEF domain
AL538_16550	COG1454	alcohol dehydrogenase
AL538_16555	COG0814	amino acid
AL538_16570	COG1120	ATPase activity
AL538_16575	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL538_16580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL538_16585	COG4774	siderophore transport
AL538_16600	COG1132	(ABC) transporter
AL538_16605	COG1132	(ABC) transporter
AL538_16620	COG0583	DNA-binding transcription factor activity
AL538_16645	COG0443	Heat shock 70 kDa protein
AL538_16650	COG0443	Heat shock 70 kDa protein
AL538_16660	COG3706	GGDEF domain
AL538_16690	COG0243	molybdopterin cofactor binding
AL538_16695	COG0437	4 iron, 4 sulfur cluster binding
AL538_16700	COG3302	dmso reductase anchor subunit
AL538_16715	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AL538_16720	COG1643	Atp-dependent helicase
AL538_16745	COG3063	Type IV pilus biogenesis stability protein PilW
AL538_16770	COG0531	amino acid
AL538_16775	COG1280	lysine exporter protein (LysE YggA)
AL538_16780	COG0583	DNA-binding transcription factor activity
AL538_16785	COG1560	Kdo2-lipid A biosynthetic process
AL538_16800	COG1846	Transcriptional regulator
AL538_16810	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
AL538_16815	COG2197	response regulator
AL538_16850	COG1280	lysine exporter protein (LysE YggA)
AL538_16865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL538_16875	COG0730	response to heat
AL538_16900	COG0456	acetyltransferase
AL538_16910	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL538_17005	COG3501	Rhs element vgr protein
AL538_17020	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AL538_17025	COG0372	Belongs to the citrate synthase family
AL538_17035	COG2828	Protein conserved in bacteria
AL538_17060	COG0561	phosphatase activity
AL538_17065	COG0602	queuosine metabolic process
AL538_17075	COG2203	Gaf domain
AL538_17075	COG2199	diguanylate cyclase activity
AL538_17105	COG3064	Membrane
AL538_17115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL538_17125	COG0297	glycogen (starch) synthase activity
AL538_17165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL538_17175	COG0573	inorganic phosphate transmembrane transporter activity
AL538_17185	COG4191	Histidine kinase
AL538_17195	COG0110	maltose O-acetyltransferase activity
AL538_17230	COG0840	transmembrane signaling receptor activity
AL538_17235	COG0714	Associated with various cellular activities
AL538_17255	COG2304	oxidoreductase activity
AL538_17270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL538_17275	COG0581	inorganic phosphate transmembrane transporter activity
AL538_17280	COG0573	inorganic phosphate transmembrane transporter activity
AL538_17285	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL538_17290	COG0840	transmembrane signaling receptor activity
AL538_17310	COG4771	TonB-dependent receptor
AL538_17315	COG1770	oligopeptidase
AL538_17325	COG0513	Belongs to the DEAD box helicase family
AL538_17335	COG1376	ErfK ybiS ycfS ynhG family protein
AL538_17335	COG1388	LysM domain
AL538_17340	COG0415	Belongs to the DNA photolyase family
AL538_17345	COG0789	Transcriptional regulator
AL538_17350	COG3272	Protein of unknown function (DUF1722)
AL538_17355	COG0813	purine-nucleoside phosphorylase activity
AL538_17370	COG3706	GGDEF domain
AL538_17385	COG1566	PFAM secretion protein HlyD family protein
AL538_17395	COG1122	ATPase activity
AL538_17415	COG0348	domain, Protein
AL538_17420	COG0437	4 iron, 4 sulfur cluster binding
AL538_17455	COG1067	ATP-dependent peptidase activity
AL538_17465	COG4172	Belongs to the ABC transporter superfamily
AL538_17470	COG1505	serine-type exopeptidase activity
AL538_17475	COG0583	DNA-binding transcription factor activity
AL538_17480	COG1620	l-lactate permease
AL538_17485	COG1304	FMN binding
AL538_17495	COG0668	transmembrane transport
AL538_17510	COG4948	Mandelate Racemase Muconate Lactonizing
AL538_17515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL538_17535	COG1342	Belongs to the UPF0251 family
AL538_17545	COG4176	ABC-type proline glycine betaine transport system permease component
AL538_17550	COG4175	Glycine betaine
AL538_17550	COG3448	diguanylate cyclase activity
AL538_17565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL538_17570	COG0589	response to stress
AL538_17575	COG0583	DNA-binding transcription factor activity
AL538_17625	COG1335	isochorismatase
AL538_17640	COG0753	catalase activity
AL538_17665	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL538_17670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL538_17670	COG1263	PTS System
AL538_17675	COG1609	Transcriptional regulator
AL538_17680	COG1349	DNA-binding transcription factor activity
AL538_17685	COG0346	lactoylglutathione lyase activity
AL538_17690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL538_17690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL538_17700	COG1263	PTS System
AL538_17700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL538_17710	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AL538_17715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL538_17720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL538_17725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL538_17740	COG0561	phosphatase activity
AL538_17755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_17760	COG3537	Alpha-1,2-mannosidase
AL538_17765	COG3537	Alpha-1,2-mannosidase
AL538_17775	COG3537	Alpha-1,2-mannosidase
AL538_17780	COG3537	Alpha-1,2-mannosidase
AL538_17795	COG1280	lysine exporter protein (LysE YggA)
AL538_17800	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL538_17815	COG3226	Transcriptional regulator
AL538_17820	COG0583	DNA-binding transcription factor activity
AL538_17840	COG0435	Glutathione S-transferase
AL538_17845	COG0431	NADPH-dependent FMN reductase
AL538_17850	COG0583	DNA-binding transcription factor activity
AL538_17855	COG4628	conserved protein (DUF2132)
AL538_17860	COG0488	(ABC) transporter
AL538_17875	COG0346	lactoylglutathione lyase activity
AL538_17880	COG0384	phenazine biosynthesis protein PhzF
AL538_17895	COG3220	belongs to the UPF0276 family
AL538_17910	COG1271	oxidase subunit
AL538_17915	COG1294	oxidase, subunit
AL538_17955	COG2207	Transcriptional regulator
AL538_17970	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AL538_17975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AL538_17990	COG2205	protein histidine kinase activity
AL538_17995	COG0745	RESPONSE REGULATOR receiver
AL538_18005	COG0454	-acetyltransferase
AL538_18015	COG2814	Major facilitator Superfamily
AL538_18030	COG0583	DNA-binding transcription factor activity
AL538_18035	COG2988	succinylglutamate desuccinylase activity
AL538_18075	COG0628	permease
AL538_18080	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AL538_18095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL538_18105	COG4628	conserved protein (DUF2132)
AL538_18110	COG0583	DNA-binding transcription factor activity
AL538_18135	COG1686	Belongs to the peptidase S11 family
AL538_18165	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL538_18170	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL538_18185	COG0415	Belongs to the DNA photolyase family
AL538_18190	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AL538_18200	COG4667	esterase of the alpha-beta hydrolase superfamily
AL538_18205	COG2095	MarC family integral membrane protein
AL538_18240	COG0583	DNA-binding transcription factor activity
AL538_18270	COG1301	dicarboxylic acid transport
AL538_18285	COG3339	Conserved Protein
AL538_18290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL538_18295	COG0700	Nucleoside recognition
AL538_18300	COG3366	ferrous iron transmembrane transporter activity
AL538_18315	COG0366	Alpha amylase catalytic
AL538_18320	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL538_18325	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL538_18330	COG1640	4-alpha-glucanotransferase
AL538_18335	COG0058	SHG alpha-glucan phosphorylase activity
AL538_18365	COG1263	PTS System
AL538_18365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL538_18370	COG1162	GTPase activity
AL538_18375	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AL538_18380	COG0673	inositol 2-dehydrogenase activity
AL538_18405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL538_18410	COG0673	inositol 2-dehydrogenase activity
AL538_18415	COG3962	Belongs to the TPP enzyme family
AL538_18425	COG2814	Major facilitator Superfamily
AL538_18425	COG0477	Major facilitator Superfamily
AL538_18430	COG0583	DNA-binding transcription factor activity
AL538_18445	COG0183	Belongs to the thiolase family
AL538_18475	COG0531	amino acid
AL538_18480	COG1982	Orn Lys Arg decarboxylase major
AL538_18500	COG1929	Belongs to the glycerate kinase type-1 family
AL538_18505	COG3835	regulator
AL538_18510	COG1228	amidohydrolase
AL538_18585	COG1132	(ABC) transporter
AL538_18590	COG1132	(ABC) transporter
AL538_18595	COG4771	TonB-dependent receptor
AL538_18635	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AL538_18635	COG3408	Glycogen debranching enzyme
AL538_18655	COG2814	Major facilitator Superfamily
AL538_18675	COG3047	cAMP biosynthetic process
AL538_18680	COG1357	PFAM Pentapeptide repeats (8 copies)
AL538_18705	COG2076	Multidrug Resistance protein
AL538_18740	COG0583	DNA-binding transcription factor activity
AL538_18755	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AL538_18770	COG3152	Membrane
AL538_18780	COG2199	diguanylate cyclase activity
AL538_18790	COG0561	phosphatase activity
AL538_18800	COG0564	pseudouridine synthase activity
AL538_18805	COG0534	Mate efflux family protein
AL538_18810	COG1609	Transcriptional regulator
AL538_18815	COG3842	ATPase activity
AL538_18820	COG2723	6-phospho-beta-galactosidase activity
AL538_18825	COG0395	ABC-type sugar transport system, permease component
AL538_18840	COG1609	Transcriptional regulator
AL538_18845	COG4580	involved in the transport of maltose and maltodextrins
AL538_18850	COG5001	Diguanylate cyclase
AL538_18910	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AL538_18930	COG0191	fructose-bisphosphate aldolase activity
AL538_18940	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_18945	COG3716	PTS system mannose fructose sorbose family IID component
AL538_18950	COG3715	PTS system
AL538_18955	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AL538_18960	COG2222	sugar isomerase
AL538_18970	COG1349	DNA-binding transcription factor activity
AL538_18975	COG1349	DNA-binding transcription factor activity
AL538_18985	COG1136	(ABC) transporter
AL538_19020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL538_19025	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
AL538_19035	COG2259	Doxx family
AL538_19070	COG3623	hexulose-6-phosphate isomerase
AL538_19075	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
AL538_19080	COG0561	phosphatase activity
AL538_19130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL538_19135	COG0251	oxidation-reduction process
AL538_19155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL538_19165	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL538_19170	COG2207	Transcriptional regulator
AL538_19180	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AL538_19225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AL538_19250	COG0786	glutamate:sodium symporter activity
AL538_19255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL538_19260	COG1131	(ABC) transporter
AL538_19275	COG0786	glutamate:sodium symporter activity
AL538_19300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL538_19305	COG3279	Response regulator of the LytR AlgR family
AL538_19310	COG3275	phosphorelay sensor kinase activity
AL538_19330	COG1136	(ABC) transporter
AL538_19340	COG0583	DNA-binding transcription factor activity
AL538_19345	COG1566	PFAM secretion protein HlyD family protein
AL538_19360	COG0772	Belongs to the SEDS family
AL538_19400	COG0444	Belongs to the ABC transporter superfamily
AL538_19405	COG4608	Belongs to the ABC transporter superfamily
AL538_19430	COG1444	tRNA N-acetyltransferase activity
AL538_19435	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL538_19440	COG0848	biopolymer transport protein
AL538_19445	COG0811	peptide transport
AL538_19480	COG1595	DNA-templated transcription, initiation
AL538_19510	COG4166	transmembrane transport
AL538_19580	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL538_19630	COG1132	(ABC) transporter
AL538_19645	COG0517	IMP dehydrogenase activity
AL538_19645	COG0516	GMP reductase activity
AL538_19655	COG0641	radical SAM
AL538_19665	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AL538_19675	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
AL538_19680	COG1028	Short-chain dehydrogenase reductase Sdr
AL538_19685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL538_19690	COG0800	Aldolase
AL538_19705	COG3119	arylsulfatase activity
AL538_19710	COG2149	membrane
AL538_19735	COG2957	Belongs to the agmatine deiminase family
AL538_19740	COG0531	amino acid
AL538_19745	COG0549	Belongs to the carbamate kinase family
AL538_19760	COG0800	Aldolase
AL538_19765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL538_19770	COG1904	glucuronate isomerase
AL538_19775	COG0246	Mannitol dehydrogenase
AL538_19785	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL538_19795	COG2186	Transcriptional regulator
AL538_19800	COG1312	Catalyzes the dehydration of D-mannonate
AL538_19805	COG3655	Transcriptional regulator
AL538_19820	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL538_19825	COG1595	DNA-templated transcription, initiation
AL538_19830	COG0583	DNA-binding transcription factor activity
AL538_19845	COG0513	Belongs to the DEAD box helicase family
AL538_19850	COG3713	MltA-interacting MipA family protein
AL538_19860	COG2153	protein acetylation
AL538_19865	COG2258	MOSC domain
AL538_19880	COG1522	sequence-specific DNA binding
AL538_19890	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AL538_19905	COG0346	lactoylglutathione lyase activity
AL538_19950	COG0366	Alpha amylase catalytic
AL538_19955	COG0583	DNA-binding transcription factor activity
AL538_19980	COG3634	alkyl hydroperoxide reductase activity
AL538_19985	COG0450	alkyl hydroperoxide reductase
AL538_19990	COG1846	Transcriptional regulator
AL538_19995	COG1764	response to oxidative stress
AL538_20010	COG0840	transmembrane signaling receptor activity
AL538_20015	COG0612	Peptidase, M16
AL538_20040	COG0739	heme binding
AL538_20065	COG4604	ABC transporter, ATP-binding protein
AL538_20070	COG4605	iron ion homeostasis
AL538_20075	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL538_20080	COG4607	ABC-type enterochelin transport system periplasmic component
AL538_20085	COG0583	DNA-binding transcription factor activity
AL538_20090	COG4771	TonB-dependent receptor
AL538_20110	COG2814	Major facilitator Superfamily
AL538_20125	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL538_20150	COG2199	diguanylate cyclase activity
AL538_20150	COG2203	Gaf domain
AL538_20175	COG0366	Alpha amylase catalytic
AL538_20180	COG2356	endonuclease I
AL538_20185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL538_20230	COG0456	acetyltransferase
AL538_20250	COG1028	Short-chain dehydrogenase reductase Sdr
AL538_20260	COG3005	denitrification pathway
AL538_20265	COG0243	molybdopterin cofactor binding
AL538_20270	COG0671	phosphoesterase, PA-phosphatase related
AL538_20285	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AL538_20290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL538_20295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL538_20300	COG1116	anion transmembrane transporter activity
AL538_20305	COG0351	phosphomethylpyrimidine kinase
AL538_20310	COG0312	modulator of DNA gyrase
AL538_20315	COG0312	modulator of DNA gyrase
AL538_20425	COG1204	response to ionizing radiation
AL538_20435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AL538_20445	COG0584	glycerophosphoryl diester phosphodiesterase
AL538_20455	COG0745	RESPONSE REGULATOR receiver
AL538_20475	COG0811	peptide transport
AL538_20480	COG0811	peptide transport
AL538_20485	COG0848	biopolymer transport protein
AL538_20530	COG0803	Belongs to the bacterial solute-binding protein 9 family
AL538_20535	COG1121	(ABC) transporter
AL538_20540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL538_20555	COG1770	oligopeptidase
AL538_20560	COG2814	Major facilitator Superfamily
AL538_20565	COG0010	Belongs to the arginase family
AL538_20570	COG1166	arginine decarboxylase activity
AL538_20580	COG4067	protein conserved in archaea
AL538_20580	COG0189	ligase activity
AL538_20585	COG0189	ligase activity
AL538_20610	COG0583	DNA-binding transcription factor activity
AL538_20650	COG1114	Component of the transport system for branched-chain amino acids
AL538_20670	COG0579	oxidoreductase
AL538_20685	COG3033	Beta-eliminating lyase
AL538_20700	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AL538_20705	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL538_20725	COG3706	GGDEF domain
AL538_20740	COG3706	GGDEF domain
AL538_20745	COG0415	Belongs to the DNA photolyase family
AL538_20750	COG3046	protein related to deoxyribodipyrimidine photolyase
AL538_20760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL538_20760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL538_20765	COG1765	OsmC-like protein
AL538_20815	COG1011	Hydrolase
AL538_20850	COG3240	lipase activity
AL538_20880	COG1609	Transcriptional regulator
AL538_20900	COG1840	ABC-type Fe3 transport system, periplasmic component
AL538_20905	COG3842	ATPase activity
AL538_20930	COG2990	Protein conserved in bacteria
AL538_20940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL538_20945	COG2866	Carboxypeptidase
AL538_20955	COG0583	DNA-binding transcription factor activity
AL538_20985	COG1760	l-serine dehydratase
AL538_21010	COG0741	lytic transglycosylase activity
AL538_21010	COG1388	LysM domain
AL538_21030	COG1815	bacterial-type flagellum-dependent cell motility
AL538_21035	COG1558	bacterial-type flagellum-dependent cell motility
AL538_21040	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AL538_21045	COG1749	Flagellar hook protein flgE
AL538_21050	COG4787	bacterial-type flagellum-dependent cell motility
AL538_21055	COG4786	Flagellar basal body rod
AL538_21060	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AL538_21065	COG1706	bacterial-type flagellum-dependent cell motility
AL538_21075	COG1256	bacterial-type flagellum assembly
AL538_21075	COG4786	Flagellar basal body rod
AL538_21080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL538_21115	COG1253	flavin adenine dinucleotide binding
AL538_21120	COG3710	Transcriptional regulator
AL538_21135	COG2226	methyltransferase
AL538_21155	COG0672	)-iron permease
AL538_21180	COG1136	(ABC) transporter
AL538_21280	COG1360	Flagellar Motor Protein
AL538_21285	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AL538_21290	COG1191	sigma factor activity
AL538_21295	COG1580	Controls the rotational direction of flagella during chemotaxis
AL538_21310	COG1516	flagellar protein fliS
AL538_21315	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AL538_21325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AL538_21340	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AL538_21350	COG1987	bacterial-type flagellum assembly
AL538_21375	COG2204	response regulator
AL538_21390	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AL538_21410	COG2200	EAL domain
AL538_21450	COG0346	lactoylglutathione lyase activity
AL538_21475	COG0745	RESPONSE REGULATOR receiver
AL538_21500	COG0156	8-amino-7-oxononanoate synthase activity
AL538_21505	COG1063	alcohol dehydrogenase
AL538_21535	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL538_21560	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL538_21595	COG3338	carbonate dehydratase activity
AL538_21625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AL538_21635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL538_21690	COG0318	PFAM AMP-dependent synthetase and ligase
AL538_21695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL538_21725	COG0786	glutamate:sodium symporter activity
AL538_21730	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL538_21735	COG1538	Outer membrane efflux protein
AL538_21745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL538_21750	COG0583	DNA-binding transcription factor activity
AL538_21765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL538_21770	COG2197	response regulator
AL538_21780	COG0574	Belongs to the PEP-utilizing enzyme family
AL538_21780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL538_21790	COG0252	asparaginase activity
AL538_21805	COG0583	DNA-binding transcription factor activity
AL538_21825	COG3122	Protein conserved in bacteria
AL538_21840	COG1902	pentaerythritol trinitrate reductase activity
AL538_21850	COG2814	Major facilitator Superfamily
AL538_21855	COG1028	Short-chain dehydrogenase reductase Sdr
AL538_21880	COG0583	DNA-binding transcription factor activity
AL538_21890	COG0513	Belongs to the DEAD box helicase family
AL538_21910	COG0095	Lipoate-protein ligase
AL538_21930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL538_21935	COG2207	Transcriptional regulator
AL538_21935	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AL538_21940	COG0583	DNA-binding transcription factor activity
AL538_21950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL538_21985	COG1566	PFAM secretion protein HlyD family protein
AL538_21990	COG0583	DNA-binding transcription factor activity
AL538_22005	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_22005	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_22005	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_22010	COG2207	Transcriptional regulator
AL538_22020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_22025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_22030	COG0583	DNA-binding transcription factor activity
AL538_22040	COG2084	Dehydrogenase
AL538_22045	COG0753	catalase activity
AL538_22055	COG2130	NADP-dependent
AL538_22060	COG1309	transcriptional regulator
AL538_22095	COG0438	transferase activity, transferring glycosyl groups
AL538_22105	COG3206	protein involved in exopolysaccharide biosynthesis
AL538_22105	COG0489	protein tyrosine kinase activity
AL538_22125	COG3842	ATPase activity
AL538_22135	COG1175	transmembrane transport
AL538_22185	COG0741	lytic transglycosylase activity
AL538_22210	COG2354	Protein conserved in bacteria
AL538_22220	COG0633	Ferredoxin
AL538_22220	COG3217	Mosc domain protein beta barrel domain protein
AL538_22220	COG0633	Ferredoxin
AL538_22220	COG3217	Mosc domain protein beta barrel domain protein
AL538_22230	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL538_22270	COG0583	DNA-binding transcription factor activity
AL538_22290	COG2814	Major facilitator Superfamily
AL538_22295	COG1335	isochorismatase
AL538_22300	COG4977	sequence-specific DNA binding
AL538_22310	COG2194	sulfuric ester hydrolase activity
AL538_22315	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AL538_22325	COG2205	protein histidine kinase activity
AL538_22330	COG0745	RESPONSE REGULATOR receiver
AL538_22335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL538_22340	COG4948	Mandelate Racemase Muconate Lactonizing
AL538_22345	COG3976	FMN-binding domain protein
AL538_22345	COG1053	succinate dehydrogenase
AL538_22360	COG4221	oxidoreductase activity
AL538_22375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL538_22395	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL538_22420	COG1418	mRNA catabolic process
AL538_22435	COG0402	S-adenosylhomocysteine deaminase activity
AL538_22440	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AL538_22445	COG2239	Acts as a magnesium transporter
AL538_22450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL538_22455	COG1566	PFAM secretion protein HlyD family protein
AL538_22480	COG0745	RESPONSE REGULATOR receiver
AL538_22485	COG2205	protein histidine kinase activity
AL538_22495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL538_22500	COG0531	amino acid
AL538_22505	COG1522	sequence-specific DNA binding
AL538_22515	COG0583	DNA-binding transcription factor activity
AL538_22535	COG2205	protein histidine kinase activity
AL538_22535	COG0784	Response regulator, receiver
AL538_22535	COG5002	protein histidine kinase activity
AL538_22540	COG0673	inositol 2-dehydrogenase activity
AL538_22545	COG0534	Mate efflux family protein
AL538_22550	COG2926	Belongs to the UPF0265 family
AL538_22615	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL538_22620	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL538_22630	COG1280	lysine exporter protein (LysE YggA)
AL538_22640	COG0183	Belongs to the thiolase family
AL538_22660	COG3005	denitrification pathway
AL538_22680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL538_22685	COG3850	Histidine kinase
AL538_22690	COG2197	response regulator
AL538_22705	COG2195	Cleaves the N-terminal amino acid of tripeptides
AL538_22725	COG0840	transmembrane signaling receptor activity
AL538_22735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL538_22765	COG0545	Peptidyl-prolyl cis-trans isomerase
AL538_22795	COG1278	Cold shock
AL538_22800	COG3036	rescue of stalled ribosome
AL538_22810	COG2199	diguanylate cyclase activity
AL538_22825	COG0577	efflux transmembrane transporter activity
AL538_22825	COG1136	(ABC) transporter
AL538_22830	COG1136	(ABC) transporter
AL538_22830	COG0577	efflux transmembrane transporter activity
AL538_22860	COG1538	Outer membrane efflux protein
AL538_22865	COG0784	Response regulator, receiver
AL538_22865	COG2205	protein histidine kinase activity
AL538_22890	COG0840	transmembrane signaling receptor activity
AL538_22895	COG0783	Belongs to the Dps family
AL538_22905	COG1619	proteins homologs of microcin C7 resistance protein MccF
AL538_22910	COG2133	pyrroloquinoline quinone binding
AL538_22915	COG1454	alcohol dehydrogenase
AL538_22925	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL538_22945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AL538_22950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL538_22960	COG3186	Phenylalanine-4-hydroxylase
AL538_22990	COG3530	Putative quorum-sensing-regulated virulence factor
AL538_23025	COG1289	transmembrane transporter activity
AL538_23030	COG0210	DNA helicase
AL538_23040	COG1879	ABC-type sugar transport system periplasmic component
AL538_23045	COG2205	protein histidine kinase activity
AL538_23045	COG0784	Response regulator, receiver
AL538_23045	COG2198	Histidine kinase
AL538_23075	COG3119	arylsulfatase activity
AL538_23080	COG3119	arylsulfatase activity
AL538_23090	COG0583	DNA-binding transcription factor activity
AL538_23095	COG3119	arylsulfatase activity
AL538_23100	COG0641	radical SAM
AL538_23105	COG0714	Associated with various cellular activities
AL538_23165	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL538_23175	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL538_23185	COG0583	DNA-binding transcription factor activity
AL538_23190	COG1597	lipid kinase activity
AL538_23195	COG3111	PFAM Bacterial OB fold (BOF) protein
AL538_23215	COG0641	radical SAM
AL538_23240	COG0501	Belongs to the peptidase M48B family
AL538_23245	COG1704	LemA family
AL538_23250	COG3069	C4-dicarboxylate transmembrane transporter activity
AL538_23280	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AL538_23285	COG0739	heme binding
AL538_23325	COG3501	Rhs element vgr protein
AL538_23350	COG0515	serine threonine protein kinase
AL538_23385	COG1522	sequence-specific DNA binding
AL538_23445	COG0457	Tetratricopeptide repeat
AL538_23450	COG0477	Major facilitator Superfamily
AL538_23450	COG2814	Major facilitator Superfamily
AL538_23455	COG1940	carbohydrate kinase activity
AL538_23460	COG2017	converts alpha-aldose to the beta-anomer
AL538_23465	COG0019	diaminopimelate decarboxylase activity
AL538_23470	COG4264	IucA IucC family
AL538_23495	COG4772	TonB-dependent receptor
AL538_23500	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
AL538_23505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL538_23510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL538_23515	COG1120	ATPase activity
AL538_23520	COG4771	TonB-dependent receptor
AL538_23535	COG2205	protein histidine kinase activity
AL538_23535	COG0784	Response regulator, receiver
AL538_23540	COG5001	Diguanylate cyclase
AL538_23540	COG3300	MHYT domain
AL538_23545	COG2197	response regulator
AL538_23550	COG3706	GGDEF domain
AL538_23560	COG2197	response regulator
AL538_23570	COG0778	Nitroreductase
AL538_23580	COG0835	chemotaxis
AL538_23580	COG0784	Response regulator, receiver
AL538_23595	COG2962	Rard protein
AL538_23620	COG3278	Belongs to the heme-copper respiratory oxidase family
AL538_23645	COG1024	Enoyl-CoA hydratase
AL538_23650	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL538_23655	COG1960	acyl-CoA dehydrogenase activity
AL538_23665	COG0183	Belongs to the thiolase family
AL538_23680	COG1024	Enoyl-CoA hydratase
AL538_23685	COG1024	Enoyl-CoA hydratase
AL538_23695	COG1028	Short-chain dehydrogenase reductase Sdr
AL538_23700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL538_23705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AL538_23710	COG1845	cytochrome c oxidase, subunit III
AL538_23715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AL538_23725	COG1902	pentaerythritol trinitrate reductase activity
AL538_23725	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL538_23730	COG0671	phosphoesterase, PA-phosphatase related
AL538_23740	COG2076	Multidrug Resistance protein
AL538_23770	COG1132	(ABC) transporter
AL538_23785	COG1733	regulation of RNA biosynthetic process
AL538_23795	COG2176	DNA-directed DNA polymerase activity
AL538_23865	COG0509	glycine decarboxylation via glycine cleavage system
AL538_23870	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL538_23880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL538_23890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL538_23895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL538_23925	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AL538_23925	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_23925	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_23930	COG1105	Belongs to the carbohydrate kinase PfkB family
AL538_23935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_23935	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_23940	COG1609	Transcriptional regulator
AL538_23955	COG2199	diguanylate cyclase activity
AL538_23955	COG2200	EAL domain
AL538_23955	COG2203	Gaf domain
AL538_23960	COG0765	amino acid transport
AL538_23965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL538_23970	COG0765	amino acid transport
AL538_23975	COG1126	abc transporter atp-binding protein
AL538_23985	COG1979	alcohol dehydrogenase
AL538_23990	COG2207	Transcriptional regulator
AL538_24000	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL538_24010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL538_24025	COG3437	response regulator, receiver
AL538_24025	COG0784	Response regulator, receiver
AL538_24030	COG0546	phosphoglycolate phosphatase activity
AL538_24045	COG0513	Belongs to the DEAD box helicase family
AL538_24050	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AL538_24065	COG3038	cytochrome b561
AL538_24075	COG2116	formate transmembrane transporter activity
AL538_24080	COG0583	DNA-binding transcription factor activity
AL538_24090	COG3593	DNA synthesis involved in DNA repair
AL538_24095	COG0737	Belongs to the 5'-nucleotidase family
AL538_24115	COG1410	methionine synthase
AL538_24115	COG0646	methionine synthase
AL538_24130	COG2267	carboxylic ester hydrolase activity
AL538_24135	COG2067	long-chain fatty acid transport protein
AL538_24150	COG2050	protein possibly involved in aromatic compounds catabolism
AL538_24160	COG4533	DNA binding
AL538_24185	COG0484	heat shock protein binding
AL538_24195	COG3300	MHYT domain
AL538_24195	COG5001	Diguanylate cyclase
AL538_24200	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL538_24210	COG4181	ATPase activity
AL538_24215	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL538_24225	COG1984	allophanate hydrolase subunit 2
AL538_24230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AL538_24240	COG5001	Diguanylate cyclase
AL538_24240	COG5002	protein histidine kinase activity
AL538_24240	COG3447	MASE1 domain protein
AL538_24245	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL538_24255	COG0583	DNA-binding transcription factor activity
AL538_24265	COG1042	CoA-binding domain protein
AL538_24265	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL538_24265	COG0045	succinate-CoA ligase (ADP-forming) activity
AL538_24285	COG0023	Translation Initiation Factor
AL538_24335	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AL538_24340	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL538_24355	COG3706	GGDEF domain
AL538_24370	COG2203	Gaf domain
AL538_24370	COG3706	GGDEF domain
AL538_24370	COG4251	negative regulation of phosphorylation
AL538_24370	COG5001	Diguanylate cyclase
AL538_24380	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AL538_24385	COG4149	molybdate abc transporter
AL538_24390	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL538_24400	COG3111	PFAM Bacterial OB fold (BOF) protein
AL538_24410	COG4067	protein conserved in archaea
AL538_24410	COG0189	ligase activity
AL538_24425	COG0534	Mate efflux family protein
AL538_24430	COG0602	queuosine metabolic process
AL538_24435	COG1328	CTP reductase activity
AL538_24495	COG2197	response regulator
AL538_24500	COG3851	Histidine kinase
AL538_24505	COG2271	Major facilitator Superfamily
AL538_24510	COG1482	cell wall glycoprotein biosynthetic process
AL538_24520	COG0628	permease
AL538_24530	COG1566	PFAM secretion protein HlyD family protein
AL538_24555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL538_24560	COG3118	belongs to the thioredoxin family
AL538_24565	COG2814	Major facilitator Superfamily
AL538_24605	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AL538_24625	COG2116	formate transmembrane transporter activity
AL538_24630	COG2146	nitrite reductase [NAD(P)H] activity
AL538_24635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL538_24640	COG5001	Diguanylate cyclase
AL538_24715	COG0277	FAD linked oxidase domain protein
AL538_24720	COG0583	DNA-binding transcription factor activity
AL538_24730	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL538_24745	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
AL538_24755	COG1288	antiporter activity
AL538_24765	COG2814	Major facilitator Superfamily
AL538_24775	COG3040	lipid binding
AL538_24805	COG3469	chitinase activity
AL538_24815	COG0419	ATPase involved in DNA repair
AL538_24820	COG0420	3'-5' exonuclease activity
AL538_24840	COG3209	COG3209 Rhs family protein
AL538_24855	COG3501	Rhs element vgr protein
AL538_24910	COG0631	protein serine/threonine phosphatase activity
AL538_24945	COG0515	serine threonine protein kinase
AL538_24945	COG2815	serine threonine protein kinase
AL538_24970	COG0346	lactoylglutathione lyase activity
AL538_24975	COG1902	pentaerythritol trinitrate reductase activity
AL538_24985	COG2755	lipolytic protein G-D-S-L family
AL538_24985	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AL538_25000	COG0069	glutamate synthase activity
AL538_25000	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL538_25010	COG1234	tRNA 3'-trailer cleavage
AL538_25015	COG2067	long-chain fatty acid transport protein
AL538_25090	COG3706	GGDEF domain
AL538_25090	COG0745	RESPONSE REGULATOR receiver
AL538_25095	COG1024	Enoyl-CoA hydratase
AL538_25100	COG0628	permease
AL538_25125	COG3038	cytochrome b561
AL538_25135	COG0739	heme binding
AL538_25185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL538_25185	COG2146	nitrite reductase [NAD(P)H] activity
AL538_25190	COG1116	anion transmembrane transporter activity
AL538_25195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL538_25200	COG1116	anion transmembrane transporter activity
AL538_25200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL538_25220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL538_25220	COG1648	precorrin-2 dehydrogenase activity
AL538_25225	COG0243	molybdopterin cofactor binding
AL538_25230	COG0456	acetyltransferase
AL538_25235	COG5001	Diguanylate cyclase
AL538_25235	COG5002	protein histidine kinase activity
AL538_25240	COG0814	amino acid
AL538_25245	COG3706	GGDEF domain
AL538_25265	COG1785	Belongs to the alkaline phosphatase family
AL538_25280	COG0745	RESPONSE REGULATOR receiver
AL538_25310	COG2847	Copper chaperone PCu(A)C
AL538_25315	COG0443	Heat shock 70 kDa protein
AL538_25370	COG3976	FMN-binding domain protein
AL538_25370	COG1053	succinate dehydrogenase
AL538_25370	COG0431	NADPH-dependent FMN reductase
AL538_25375	COG5002	protein histidine kinase activity
AL538_25380	COG0745	RESPONSE REGULATOR receiver
AL538_25410	COG4160	amino acid transport
AL538_25415	COG4215	(ABC) transporter
AL538_25420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL538_25425	COG1126	abc transporter atp-binding protein
AL538_25460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL538_25470	COG1012	belongs to the aldehyde dehydrogenase family
AL538_25480	COG0583	DNA-binding transcription factor activity
AL538_25485	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL538_25490	COG0513	Belongs to the DEAD box helicase family
AL538_25495	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
AL538_25510	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AL538_25550	COG5290	Psort location Cytoplasmic, score
AL538_25580	COG2205	protein histidine kinase activity
AL538_25585	COG0745	RESPONSE REGULATOR receiver
AL538_25590	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AL538_25595	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AL538_25605	COG1119	ATPase activity
AL538_25610	COG2771	luxR family
AL538_25610	COG2200	EAL domain
AL538_25630	COG0513	Belongs to the DEAD box helicase family
AL538_25635	COG3447	MASE1 domain protein
AL538_25635	COG5001	Diguanylate cyclase
AL538_25635	COG5002	protein histidine kinase activity
AL538_25640	COG0523	cobalamin synthesis protein
AL538_25665	COG4206	TonB-dependent receptor
AL538_25675	COG0789	Transcriptional regulator
AL538_25680	COG4604	ABC transporter, ATP-binding protein
AL538_25685	COG4605	iron ion homeostasis
AL538_25690	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL538_25695	COG4607	ABC-type enterochelin transport system periplasmic component
AL538_25705	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
AL538_25720	COG1609	Transcriptional regulator
AL538_25725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL538_25730	COG1879	ABC-type sugar transport system periplasmic component
AL538_25735	COG1172	Belongs to the binding-protein-dependent transport system permease family
AL538_25740	COG1129	ABC transporter
AL538_25750	COG5001	Diguanylate cyclase
AL538_25755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AL538_25760	COG1794	racemase activity, acting on amino acids and derivatives
AL538_25775	COG3385	transposase activity
AL538_25790	COG0586	Pfam SNARE associated Golgi protein
AL538_25830	COG0784	Response regulator, receiver
AL538_25830	COG2205	protein histidine kinase activity
AL538_25840	COG2205	protein histidine kinase activity
AL538_25840	COG0784	Response regulator, receiver
AL538_25860	COG0330	HflC and HflK could
AL538_25875	COG0517	IMP dehydrogenase activity
AL538_25875	COG4175	Glycine betaine
AL538_25880	COG4176	ABC-type proline glycine betaine transport system permease component
AL538_25910	COG3706	GGDEF domain
AL538_25935	COG0204	Acyl-transferase
AL538_25965	COG2885	chlorophyll binding
AL538_26005	COG0455	bacterial-type flagellum organization
AL538_26015	COG4964	Belongs to the GSP D family
AL538_26035	COG0583	DNA-binding transcription factor activity
AL538_26040	COG1073	alpha beta
AL538_26050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL538_26050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL538_26065	COG4989	oxidoreductase activity
AL538_26090	COG1914	H( )-stimulated, divalent metal cation uptake system
AL538_26105	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AL538_26120	COG2897	thiosulfate sulfurtransferase activity
AL538_26145	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL538_26155	COG2814	Major facilitator Superfamily
AL538_26160	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL538_26175	COG1612	heme a metabolic process
AL538_26195	COG1845	cytochrome c oxidase, subunit III
AL538_26200	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AL538_26210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AL538_26215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL538_26225	COG1280	lysine exporter protein (LysE YggA)
AL538_26245	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL538_26260	COG0697	spore germination
AL538_26275	COG2814	Major facilitator Superfamily
AL538_26280	COG0583	DNA-binding transcription factor activity
AL538_26285	COG5001	Diguanylate cyclase
AL538_26290	COG0739	heme binding
AL538_26320	COG0814	amino acid
AL538_26340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AL538_26345	COG1072	(Pantothenic acid kinase))
AL538_26355	COG1063	alcohol dehydrogenase
AL538_26360	COG2213	PTS system mannitol-specific
AL538_26365	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_26370	COG2188	Transcriptional regulator
AL538_26375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_26375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AL538_26375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AL538_26380	COG0383	alpha-mannosidase activity
AL538_26385	COG1482	cell wall glycoprotein biosynthetic process
AL538_26390	COG0747	negative chemotaxis
AL538_26400	COG1733	regulation of RNA biosynthetic process
AL538_26415	COG0798	PFAM Bile acid sodium symporter
AL538_26430	COG1881	PFAM PEBP family protein
AL538_26440	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL538_26455	COG0583	DNA-binding transcription factor activity
AL538_26505	COG0366	Alpha amylase catalytic
AL538_26520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL538_26525	COG0784	Response regulator, receiver
AL538_26525	COG0835	chemotaxis
AL538_26535	COG0748	coenzyme F420 binding
AL538_26540	COG3721	Heme iron utilization protein
AL538_26550	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AL538_26555	COG0811	peptide transport
AL538_26560	COG0848	biopolymer transport protein
AL538_26570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL538_26575	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL538_26580	COG0840	transmembrane signaling receptor activity
AL538_26590	COG1131	(ABC) transporter
AL538_26595	COG0842	Transport permease protein
AL538_26600	COG0251	oxidation-reduction process
AL538_26615	COG0800	Aldolase
AL538_26620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AL538_26625	COG4145	pantothenate transmembrane transporter activity
AL538_26635	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AL538_26660	COG3383	formate dehydrogenase (NAD+) activity
AL538_26675	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL538_26715	COG0456	acetyltransferase
AL538_26735	COG0612	Peptidase, M16
AL538_26740	COG4178	(ABC) transporter
AL538_26745	COG4771	TonB-dependent receptor
AL538_26755	COG0811	peptide transport
AL538_26760	COG0811	peptide transport
AL538_26765	COG0848	biopolymer transport protein
AL538_26790	COG1858	cytochrome C peroxidase
AL538_26795	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AL538_26805	COG1505	serine-type exopeptidase activity
AL538_26810	COG0488	(ABC) transporter
AL538_26815	COG1720	tRNA m6t6A37 methyltransferase activity
AL538_26835	COG2814	Major facilitator Superfamily
AL538_26850	COG0583	DNA-binding transcription factor activity
AL538_26855	COG0589	response to stress
AL538_26880	COG1175	transmembrane transport
AL538_26885	COG0395	ABC-type sugar transport system, permease component
AL538_26890	COG3842	ATPase activity
AL538_26905	COG1846	Transcriptional regulator
AL538_26920	COG0523	cobalamin synthesis protein
AL538_26930	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AL538_26940	COG4667	esterase of the alpha-beta hydrolase superfamily
AL538_26945	COG1741	Belongs to the pirin family
AL538_26950	COG1278	Cold shock
AL538_26965	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AL538_26995	COG2226	methyltransferase
AL538_27005	COG3706	GGDEF domain
AL538_27010	COG1686	Belongs to the peptidase S11 family
AL538_27015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AL538_27020	COG2249	NAD(P)H dehydrogenase (quinone) activity
AL538_27025	COG0583	DNA-binding transcription factor activity
AL538_27030	COG0625	glutathione transferase activity
AL538_27040	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL538_27065	COG1028	Short-chain dehydrogenase reductase Sdr
AL538_27090	COG3746	phosphate-selective porin O and P
AL538_27100	COG3423	Transcriptional regulator
AL538_27105	COG2801	Transposase and inactivated derivatives
AL538_27110	COG2842	Transposition protein
AL538_27180	COG5566	PFAM Mor transcription activator
AL538_27210	COG0640	Transcriptional regulator
AL538_27220	COG4373	Mu-like prophage FluMu protein gp28
AL538_27225	COG4383	Mu-like prophage protein gp29
AL538_27245	COG4388	Caudovirus prohead serine protease
AL538_27255	COG4397	Mu-like prophage major head subunit gpT
AL538_27265	COG4387	Mu-like prophage protein GP36
AL538_27335	COG1028	Short-chain dehydrogenase reductase Sdr
AL538_27345	COG1301	dicarboxylic acid transport
AL538_27350	COG1252	NADH dehydrogenase
AL538_27360	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AL538_27365	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
AL538_27990	COG2003	Belongs to the UPF0758 family
AL538_28075	COG0456	acetyltransferase
AL538_28175	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL538_28470	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL538_28495	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL538_28510	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AL538_28510	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
AL538_28600	COG0401	homolog of Blt101
AL538_28660	COG3140	Belongs to the UPF0181 family