locus-tag	class	description
F9277_00035	ENOG4105BZU	Histidine kinase
F9277_00040	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
F9277_00045	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
F9277_00050	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
F9277_00060	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
F9277_00065	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
F9277_00070	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
F9277_00075	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F9277_00090	ENOG4105D8G	Major Facilitator superfamily
F9277_00095	ENOG4105BZU	Histidine kinase
F9277_00100	ENOG4105C9Q	fumarate hydratase class II
F9277_00115	ENOG4107QN1	sodium solute
F9277_00125	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
F9277_00135	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
F9277_00140	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
F9277_00145	ENOG4108IJ0	Aspartate ammonia-lyase
F9277_00150	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
F9277_00155	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
F9277_00165	ENOG4105E0F	Histidine kinase
F9277_00170	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
F9277_00175	ENOG4108SPG	Periplasmic Protein
F9277_00180	ENOG41076HS	cation diffusion facilitator family transporter
F9277_00185	ENOG4105CTQ	phosphohexokinase
F9277_00190	ENOG4107QI1	Mate efflux family protein
F9277_00195	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
F9277_00200	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
F9277_00215	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
F9277_00220	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
F9277_00235	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
F9277_00240	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
F9277_00255	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
F9277_00265	ENOG41062JF	Transcriptional regulator
F9277_00275	ENOG41063SB	peptidase
F9277_00280	ENOG4105D7W	serine acetyltransferase
F9277_00285	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
F9277_00290	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
F9277_00295	ENOG4107YZP	Rhodanese domain protein
F9277_00300	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
F9277_00315	ENOG4105C8P	)-transporter
F9277_00320	ENOG4105DJ4	phosphatidylserine decarboxylase
F9277_00325	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
F9277_00330	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
F9277_00395	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
F9277_00400	ENOG4105K8N	protein family UPF0079, ATPase
F9277_00405	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
F9277_00410	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
F9277_00415	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
F9277_00420	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
F9277_00425	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
F9277_00430	ENOG4107QJR	hflk protein
F9277_00435	ENOG4105EPW	hflc protein
F9277_00445	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
F9277_00455	ENOG4108UV7	flagellar protein motX
F9277_00460	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
F9277_00465	ENOG4105KPV	Transcriptional regulator
F9277_00470	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
F9277_00475	ENOG4105C2N	RNA methyltransferase TrmH family group 3
F9277_00480	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F9277_00485	ENOG4105C31	Tryptophanyl-tRNA synthetase
F9277_00495	ENOG4105FCK	Membrane
F9277_00505	ENOG4105DDQ	anthranilate synthase
F9277_00510	ENOG4105C8Y	Acetylornithine aminotransferase
F9277_00520	ENOG4105C26	Dehydrogenase
F9277_00530	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
F9277_00535	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
F9277_00540	ENOG4105YP7	UPF0270 protein
F9277_00545	ENOG4105DNZ	Alpha Beta Hydrolase
F9277_00555	ENOG4105C5H	ABC transporter
F9277_00565	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
F9277_00580	ENOG4108YZY	peptidylprolyl cis-trans isomerase
F9277_00590	ENOG4105D44	asparaginase
F9277_00595	ENOG41069P5	Protein slyX homolog
F9277_00605	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F9277_00610	ENOG4105WWK	YheO domain protein
F9277_00615	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
F9277_00620	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
F9277_00625	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
F9277_00630	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
F9277_00635	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
F9277_00640	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
F9277_00645	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
F9277_00650	ENOG4105W53	bacterioferritin-associated ferredoxin
F9277_00655	ENOG4108UQY	Iron-storage protein
F9277_00660	ENOG4105C6K	Malic enzyme
F9277_00665	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
F9277_00670	ENOG4105C28	cystathionine
F9277_00675	ENOG4105CFH	Aspartokinase
F9277_00680	ENOG4105SYT	Methylenetetrahydrofolate reductase
F9277_00690	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
F9277_00695	ENOG4105CWC	Acetylornithine deacetylase
F9277_00700	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
F9277_00705	ENOG4105CAS	nag kinase
F9277_00710	ENOG4105CDH	Citrulline--aspartate ligase
F9277_00715	ENOG4105CH7	arginosuccinase
F9277_00730	ENOG4107QN2	dihydrolipoyl dehydrogenase
F9277_00735	ENOG4105EHV	domain protein
F9277_00740	ENOG4105C5Q	Transcriptional regulator
F9277_00745	ENOG4108JQC	penicillin-binding protein 1A
F9277_00770	ENOG4105E4G	Type IV pilus
F9277_00775	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
F9277_00780	ENOG4105D49	3-dehydroquinate synthase
F9277_00790	ENOG4105DFE	Dna adenine methylase
F9277_00805	ENOG4105DJV	ribulose-phosphate 3-epimerase
F9277_00810	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
F9277_00815	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
F9277_00820	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
F9277_00830	ENOG4105CDU	Replicative dna helicase
F9277_00835	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
F9277_00845	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
F9277_00850	ENOG4107QP8	phosphohexose isomerase
F9277_00860	ENOG4105MYN	Zinc uptake regulation protein
F9277_00905	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
F9277_00925	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
F9277_00930	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
F9277_00935	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
F9277_00995	ENOG4105EEQ	Na H antiporter
F9277_01000	ENOG4105C3R	Methionine synthase
F9277_01005	ENOG4105CFH	Aspartokinase
F9277_01015	ENOG4105C5R	Aminotransferase
F9277_01025	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
F9277_01030	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
F9277_01035	ENOG41086KC	Transcriptional regulator
F9277_01040	ENOG4108UUM	single-stranded DNA-binding protein
F9277_01045	ENOG41062P1	Diguanylate cyclase phosphodiesterase
F9277_01080	ENOG4107QHF	type ii secretion system protein e
F9277_01085	ENOG4105D7Q	type ii secretion system
F9277_01095	ENOG4108VAU	general secretion pathway protein G
F9277_01130	ENOG4105DFF	Rod shape-determining protein mreb
F9277_01135	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
F9277_01140	ENOG4105VQ7	Rod shape-determining protein MreD
F9277_01145	ENOG4108Z03	MAF-like protein
F9277_01150	ENOG4105C03	ribonuclease
F9277_01155	ENOG4105QD6	exported protein
F9277_01165	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
F9277_01170	ENOG4108IAB	Phoh family
F9277_01175	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
F9277_01180	ENOG4105K3M	)-transporter
F9277_01185	ENOG4105D3G	Pseudouridine synthase
F9277_01190	ENOG4105C5I	Dehydrogenase
F9277_01195	ENOG4105N42	UPF0307 protein
F9277_01200	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
F9277_01205	ENOG4105CJW	magnesium transporter
F9277_01210	ENOG41080Z8	PHOSPHOCARRIER protein
F9277_01215	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
F9277_01220	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
F9277_01225	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
F9277_01230	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F9277_01235	ENOG4108IUZ	ABC transporter
F9277_01240	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
F9277_01250	ENOG4105C2X	Arabinose 5-phosphate isomerase
F9277_01260	ENOG4105DHJ	ABC, transporter
F9277_01265	ENOG4105CY3	ABC transporter, permease
F9277_01270	ENOG4107PE3	Mammalian cell entry related domain protein
F9277_01275	ENOG4105E3I	toluene tolerance
F9277_01285	ENOG4105VFK	BolA family
F9277_01290	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
F9277_01295	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
F9277_01300	ENOG4105KME	endoribonuclease L-psp
F9277_01305	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
F9277_01310	ENOG4105CXT	aspartate transcarbamylase
F9277_01320	ENOG4105DBV	ornithine carbamoyltransferase
F9277_01325	ENOG4105CEU	Arginine dihydrolase
F9277_01345	ENOG4108MJ3	acetyltransferase
F9277_01355	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
F9277_01360	ENOG4105MYG	DNA polymerase iii, chi subunit
F9277_01365	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
F9277_01370	ENOG4108M8S	permease YjgP YjgQ family protein
F9277_01375	ENOG4108K5H	permease YjgP YjgQ family protein
F9277_01385	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
F9277_01405	ENOG4105VZJ	PTS System
F9277_01415	ENOG4105VCP	PTS System
F9277_01420	ENOG4105F8D	glycoside hydrolase family 4
F9277_01425	ENOG410901P	UPF0249 protein
F9277_01435	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
F9277_01485	ENOG4105C26	Dehydrogenase
F9277_01515	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_01560	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
F9277_01565	ENOG4105CEN	a g-specific adenine glycosylase
F9277_01570	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
F9277_01580	ENOG4105CSV	Glutaminase
F9277_01585	ENOG4105CSA	Coproporphyrinogen iii oxidase
F9277_01590	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
F9277_01600	ENOG4105VZ9	UPF0235 protein
F9277_01605	ENOG4108VIA	integral membrane protein
F9277_01610	ENOG4105II7	pyrroline-5-carboxylate reductase
F9277_01615	ENOG4105DFA	alanine racemase domain protein
F9277_01620	ENOG4105CZX	twitching motility protein
F9277_01625	ENOG4105CZX	twitching motility protein
F9277_01630	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
F9277_01635	ENOG4108UJU	UPF0301 protein
F9277_01640	ENOG4105D7Z	glutathione synthase
F9277_01645	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
F9277_01650	ENOG4105RWS	endonuclease I
F9277_01660	ENOG4105GPY	SprT protein
F9277_01670	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
F9277_01675	ENOG4105CV1	Transketolase (EC 2.2.1.1)
F9277_01685	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
F9277_01690	ENOG4105BZA	Phosphoglycerate kinase
F9277_01695	ENOG4105D2N	Aldolase
F9277_01700	ENOG4105D64	Mechanosensitive ion channel
F9277_01715	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
F9277_01720	ENOG4105MPN	Membrane
F9277_01725	ENOG4108JQ1	Dehydrogenase
F9277_01730	ENOG4105E66	phosphoriboisomerase A
F9277_01735	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
F9277_01745	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
F9277_01760	ENOG4105D0A	hydroxylase
F9277_01765	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
F9277_01780	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
F9277_01785	ENOG4105Y75	tpr repeat protein
F9277_01795	ENOG4108IYU	L-aspartate oxidase
F9277_01805	ENOG4105EMN	RNA polymerase sigma factor
F9277_01825	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
F9277_01830	ENOG4105C3F	Signal peptidase i
F9277_01835	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
F9277_01840	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
F9277_01845	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
F9277_01850	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
F9277_01855	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
F9277_01860	ENOG4105BZU	Histidine kinase
F9277_01870	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
F9277_01875	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F9277_01880	ENOG4105DXN	mazG family
F9277_01885	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
F9277_01895	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
F9277_01900	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
F9277_01905	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
F9277_01910	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
F9277_01915	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
F9277_01920	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
F9277_01930	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F9277_01935	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
F9277_01940	ENOG4107TH8	cina domain protein
F9277_01945	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
F9277_01950	ENOG4105Y3E	Modulates RecA activity (By similarity)
F9277_01955	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
F9277_01960	ENOG4105CFH	Aspartokinase
F9277_01965	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
F9277_02020	ENOG4107QSA	Oxaloacetate decarboxylase
F9277_02025	ENOG4105D9Q	decarboxylase (Beta subunit)
F9277_02035	ENOG4105W39	Membrane
F9277_02045	ENOG4105D9M	gamma-glutamylcysteine synthetase
F9277_02055	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
F9277_02060	ENOG4108JU6	CBS domain protein
F9277_02065	ENOG4106KVJ	cytochrome C assembly protein
F9277_02070	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F9277_02075	ENOG4105K5M	30s ribosomal protein S16
F9277_02080	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
F9277_02085	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
F9277_02090	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
F9277_02100	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
F9277_02105	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
F9277_02110	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
F9277_02115	ENOG4105D7Q	type ii secretion system
F9277_02120	ENOG4107QHF	type ii secretion system protein e
F9277_02135	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
F9277_02145	ENOG41073TP	transcriptional regulator
F9277_02150	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
F9277_02155	ENOG4107QSN	dihydrolipoamide acetyltransferase
F9277_02160	ENOG4107QN2	dihydrolipoyl dehydrogenase
F9277_02165	ENOG410630P	Transcriptional regulator
F9277_02170	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
F9277_02175	ENOG41077A9	carbonic anhydrase
F9277_02180	ENOG4105CHH	sulfate transporter
F9277_02185	ENOG4105DA5	(ABC) transporter
F9277_02190	ENOG4105E3A	(ABC) transporter
F9277_02195	ENOG4105D1S	lipid A biosynthesis
F9277_02200	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
F9277_02205	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
F9277_02210	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F9277_02215	ENOG4105DJ0	Poly(A) Polymerase
F9277_02225	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
F9277_02230	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F9277_02235	ENOG4105PW4	Sugar fermentation stimulation protein homolog
F9277_02240	ENOG4105CQ7	ATP-dependent helicase
F9277_02245	ENOG4105BZ4	penicillin-binding protein
F9277_02250	ENOG4105D78	K07001 NTE family protein
F9277_02255	ENOG4107QIJ	Aconitate hydratase 2
F9277_02260	ENOG4105XTV	UPF0231 protein
F9277_02265	ENOG4108YZA	Nitrogen regulatory protein pii
F9277_02285	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F9277_02300	ENOG4105E2D	ec 3.2.1.52
F9277_02305	ENOG4105RD7	BadF BadG BcrA BcrD
F9277_02315	ENOG4108JQ7	(ABC) transporter
F9277_02320	ENOG4105C3U	ABC transporter
F9277_02325	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F9277_02335	ENOG4105DEF	Extracellular solute-binding protein, family 5
F9277_02340	ENOG4105BZU	Histidine kinase
F9277_02350	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
F9277_02355	ENOG4105F4G	Membrane
F9277_02360	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
F9277_02365	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
F9277_02370	ENOG4105CW7	secretion protein, HlyD family
F9277_02380	ENOG4105DR5	peptidase
F9277_02385	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
F9277_02395	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
F9277_02400	ENOG4107QE9	Inherit from COG: Membrane
F9277_02405	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
F9277_02410	ENOG4105HBR	Rna-binding protein
F9277_02415	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
F9277_02420	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
F9277_02425	ENOG4105EEI	dihydropteroate synthase
F9277_02430	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
F9277_02450	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
F9277_02455	ENOG4105CHV	Transcription elongation factor NusA
F9277_02460	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
F9277_02465	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
F9277_02470	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
F9277_02475	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
F9277_02480	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
F9277_02495	ENOG4105C3S	Mate efflux family protein
F9277_02500	ENOG4106RZ4	Peptidase U32
F9277_02505	ENOG4105CFP	Peptidase U32
F9277_02510	ENOG4105BZU	Histidine kinase
F9277_02515	ENOG4105XPQ	lipid carrier protein
F9277_02520	ENOG4108YYD	acetyltransferase
F9277_02540	ENOG4105BZU	Histidine kinase
F9277_02545	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
F9277_02550	ENOG4105EYA	deoxyribonuclease
F9277_02555	ENOG4105D9N	nucleoside
F9277_02560	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
F9277_02565	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
F9277_02570	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
F9277_02575	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
F9277_02585	ENOG4105EAC	phosphoserine phosphatase
F9277_02595	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
F9277_02600	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
F9277_02605	ENOG4105ETT	transcriptional Regulator, LysR family
F9277_02615	ENOG4108IQE	Amp-dependent synthetase and ligase
F9277_02705	ENOG41064T2	transcriptional regulator, lysR family
F9277_02710	ENOG4105E5D	amino acid
F9277_02715	ENOG4105FK9	beta-D-galactosidase beta subunit
F9277_02720	ENOG4105CNT	hydrolase family 2
F9277_02725	ENOG4105CQ4	Transcriptional regulator
F9277_02735	ENOG4105CJN	penicillin-binding protein
F9277_02740	ENOG4105CMR	udp-glucose 4-epimerase
F9277_02745	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
F9277_02750	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
F9277_02755	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
F9277_02765	ENOG4105CI1	PTS System
F9277_02775	ENOG4108Y51	tRNA-binding protein
F9277_02800	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
F9277_02805	ENOG4105E98	transcriptional regulator DeoR family
F9277_02810	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
F9277_02815	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
F9277_02825	ENOG4105CXY	transporter
F9277_02830	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
F9277_02835	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
F9277_02850	ENOG4105X2V	dna damage-inducible protein
F9277_02855	ENOG4105EVZ	LysR family transcriptional regulator
F9277_02865	ENOG4105E68	Sulfatase
F9277_02870	ENOG4105DSY	exodeoxyribonuclease V, gamma
F9277_02875	ENOG4107QKA	exodeoxyribonuclease V beta
F9277_02880	ENOG4107QYX	exodeoxyribonuclease v alpha
F9277_02905	ENOG4107QZM	n-acetylglutamate synthase
F9277_02920	ENOG4105CA3	membrane-bound lytic murein transglycosylase
F9277_02925	ENOG4105CUZ	uba thif-type nad fad binding protein
F9277_02930	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
F9277_02935	ENOG4105C9B	Cysteine desulfurase
F9277_02940	ENOG4107S0N	DJ-1 family
F9277_02945	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
F9277_02950	ENOG4105DRB	nucleoside-specific channel-forming protein
F9277_02970	ENOG4105K6V	RNA polymerase
F9277_02985	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
F9277_02995	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
F9277_03000	ENOG4105M85	Bola protein
F9277_03005	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F9277_03010	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F9277_03015	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F9277_03020	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F9277_03025	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F9277_03030	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
F9277_03035	ENOG4105CJ2	(LipO)protein
F9277_03045	ENOG4105BZU	Histidine kinase
F9277_03050	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
F9277_03055	ENOG4105C9U	ATP-dependent DNA helicase RecQ
F9277_03060	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
F9277_03075	ENOG4105C8J	)-transporter
F9277_03085	ENOG4105W1I	UPF0253 protein
F9277_03095	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
F9277_03100	ENOG4108R96	Methyltransferase, YaeB family
F9277_03105	ENOG4105NRA	50s ribosomal protein l31 type b
F9277_03115	ENOG4105CFC	Transporter
F9277_03140	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
F9277_03150	ENOG4108UPT	UPF0178 protein
F9277_03180	ENOG4105WP7	tRNA pseudouridine synthase C
F9277_03185	ENOG4105DR9	pseudouridine synthase
F9277_03190	ENOG4108T8E	UPF0325 protein
F9277_03195	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
F9277_03200	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
F9277_03205	ENOG4105CE9	30S ribosomal protein S2
F9277_03210	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
F9277_03215	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
F9277_03220	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
F9277_03225	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
F9277_03230	ENOG4105KNE	Phosphatidate cytidylyltransferase
F9277_03235	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
F9277_03240	ENOG4105DZP	Membrane-associated zinc metalloprotease
F9277_03250	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
F9277_03255	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F9277_03260	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
F9277_03265	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F9277_03270	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F9277_03275	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
F9277_03280	ENOG4105C0B	DNA polymerase III (alpha subunit)
F9277_03285	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
F9277_03290	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
F9277_03295	ENOG4105N7H	Cytochrome
F9277_03300	ENOG4108YZA	Nitrogen regulatory protein pii
F9277_03305	ENOG4107NA1	Endonuclease Exonuclease phosphatase
F9277_03315	ENOG4105E9H	Lytic Murein transglycosylase
F9277_03320	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
F9277_03325	ENOG4105D1A	Methyltransferase
F9277_03330	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
F9277_03335	ENOG4107RZZ	dna polymerase iii epsilon subunit
F9277_03355	ENOG4107QPN	acyl-Coa dehydrogenase
F9277_03360	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
F9277_03365	ENOG4105E7A	Glutamine amidotransferase
F9277_03370	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
F9277_03380	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
F9277_03385	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
F9277_03390	ENOG4105C2W	permease
F9277_03405	ENOG4105CS1	NAD(P)H quinone oxidoreductase
F9277_03410	ENOG4105K89	arsenate reductase
F9277_03415	ENOG4105ERG	peptidase m48, ste24p
F9277_03430	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9277_03435	ENOG4105RH4	Glycine cleavage system transcriptional repressor
F9277_03445	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F9277_03460	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
F9277_03465	ENOG4105KUZ	arsenate reductase
F9277_03485	ENOG4105QZU	Inner membrane protein YfeZ
F9277_03490	ENOG4105EZR	dyp-type peroxidase family protein
F9277_03495	ENOG4108K2B	transcriptional regulator
F9277_03500	ENOG4105F8D	glycoside hydrolase family 4
F9277_03505	ENOG4105CT4	transporter
F9277_03510	ENOG4105I03	Flagellin
F9277_03520	ENOG4105I03	Flagellin
F9277_03530	ENOG4105I03	Flagellin
F9277_03535	ENOG41063QE	flagellar protein FlaG
F9277_03540	ENOG4107BRV	flagellar capping protein
F9277_03550	ENOG4105MQ3	flagellar protein FliS
F9277_03560	ENOG4105BZU	Histidine kinase
F9277_03565	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_03570	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
F9277_03575	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
F9277_03580	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
F9277_03590	ENOG4108JIR	Flagellum-specific ATP synthase
F9277_03615	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
F9277_03620	ENOG4105DD5	Flagellar motor switch protein
F9277_03625	ENOG4105VTB	flagellar biosynthesis protein fliO
F9277_03630	ENOG4105CN7	Flagellar biosynthetic protein FliP
F9277_03635	ENOG4105VS8	Flagellar biosynthetic protein fliq
F9277_03640	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
F9277_03645	ENOG4105D00	flagellar biosynthetic protein flhB
F9277_03650	ENOG4105D7B	Flagellar biosynthesis protein flha
F9277_03655	ENOG4105FZW	flagellar biosynthesis regulator FlhF
F9277_03660	ENOG4107R21	site-determining protein
F9277_03665	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F9277_03670	ENOG4108VYJ	response regulator receiver protein
F9277_03675	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
F9277_03680	ENOG4105CBS	Chea signal transduction histidine kinase
F9277_03685	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
F9277_03690	ENOG4107QJE	Chromosome Partitioning Protein
F9277_03700	ENOG4108V3W	Chemotaxis protein, CheW
F9277_03710	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
F9277_03715	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
F9277_03720	ENOG41060IM	Heme exporter protein
F9277_03730	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
F9277_03735	ENOG4105DA4	cytochrome c-type biogenesis protein
F9277_03740	ENOG4107QX9	Thiol disulfide interChange protein
F9277_03745	ENOG4108M1T	Cytochrome c-type biogenesis protein
F9277_03750	ENOG4105KWW	Biogenesis protein
F9277_03755	ENOG410903C	(LipO)protein
F9277_03760	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
F9277_03765	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
F9277_03780	ENOG4105CHU	acetyl-coa acetyltransferase
F9277_03785	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
F9277_03795	ENOG4107QXK	peptidase
F9277_03800	ENOG4108BY2	phosphohistidine phosphatase
F9277_03805	ENOG4108DG9	Smr protein MutS2
F9277_03810	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
F9277_03815	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
F9277_03820	ENOG4105EN6	Membrane
F9277_03825	ENOG4108BPE	-transporting atpase
F9277_03830	ENOG4105MH2	YfcL protein
F9277_03840	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
F9277_03845	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F9277_03855	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
F9277_03860	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
F9277_03870	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
F9277_03880	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
F9277_03885	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
F9277_03890	ENOG4108S3P	Sporulation domain protein
F9277_03895	ENOG4105E96	Colicin v production protein
F9277_03900	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
F9277_03905	ENOG4105EJC	lysr family transcriptional regulator
F9277_03910	ENOG4105I93	response regulator
F9277_03920	ENOG4105WD1	Membrane
F9277_03925	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
F9277_03930	ENOG4107QMP	dna polymerase iii subunits gamma and tau
F9277_03935	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
F9277_03940	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
F9277_03945	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
F9277_03950	ENOG4105C44	Serine transporter
F9277_03960	ENOG4105CEM	UPF0597 protein
F9277_03965	ENOG4105WWK	YheO domain protein
F9277_03970	ENOG4105KRS	Proteinase inhibitor
F9277_03975	ENOG4108ZZ3	UPF0260 protein
F9277_03980	ENOG4105Y3U	Transglycosylase-associated protein
F9277_03990	ENOG41067V3	Antibiotic biosynthesis monooxygenase
F9277_03995	ENOG4108UYE	Lactoylglutathione lyase
F9277_04005	ENOG4105G6Z	alkaline phosphatase
F9277_04010	ENOG4105C94	Transporter
F9277_04025	ENOG4105DHI	Methyltransferase
F9277_04030	ENOG4107SDU	Methyl-accepting chemotaxis
F9277_04040	ENOG4105DSB	aldose 1-epimerase
F9277_04045	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
F9277_04050	ENOG4105E0X	reductase
F9277_04060	ENOG4105VUT	cytoplasmic protein
F9277_04065	ENOG4105HDK	L-asparaginase
F9277_04070	ENOG4105D07	Signal peptide peptidase, SppA
F9277_04075	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F9277_04080	ENOG41069NU	Nitroreductase
F9277_04085	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
F9277_04095	ENOG4108RU0	short-chain dehydrogenase reductase
F9277_04100	ENOG4105DGU	Histone deacetylase
F9277_04110	ENOG4105E68	Sulfatase
F9277_04115	ENOG4105YDX	UPF0352 protein
F9277_04120	ENOG4106V8H	Nucleoid-associated protein
F9277_04135	ENOG4105DFD	Na H antiporter
F9277_04140	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
F9277_04145	ENOG4105EYW	Ion transport protein
F9277_04150	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
F9277_04155	ENOG4108EKI	Dehydrogenase
F9277_04170	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
F9277_04175	ENOG4105M2J	Glutaredoxin
F9277_04185	ENOG4105D3Y	Na H antiporter
F9277_04190	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
F9277_04195	ENOG4105EIY	sodium-type flagellar protein motY
F9277_04200	ENOG4106WH9	Protein of unknown function (DUF2753)
F9277_04205	ENOG4108UYE	Lactoylglutathione lyase
F9277_04210	ENOG4105CSM	endonuclease III
F9277_04215	ENOG4105DZB	Electron transport complex
F9277_04220	ENOG4108UQQ	Electron transport complex
F9277_04225	ENOG4105D6A	Electron transport complex
F9277_04235	ENOG4108R3D	Electron transport complex
F9277_04240	ENOG4105DGN	Electron transport complex
F9277_04245	ENOG4105C6N	Formate acetyltransferase
F9277_04255	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
F9277_04260	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_04270	ENOG4105CHW	UPF0052 protein
F9277_04275	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F9277_04280	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
F9277_04285	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
F9277_04290	ENOG4105M00	molybdopterin converting factor, subunit 1
F9277_04295	ENOG4108ZAF	Molybdopterin
F9277_04300	ENOG4107QSI	ABC, transporter
F9277_04305	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
F9277_04310	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F9277_04315	ENOG4105C3U	ABC transporter
F9277_04320	ENOG4108JQ7	(ABC) transporter
F9277_04325	ENOG4105CHF	Glutathione S-transferase
F9277_04330	ENOG4107PU6	Membrane
F9277_04335	ENOG4108DNC	Involved in acetate metabolism (By similarity)
F9277_04340	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
F9277_04345	ENOG4105PQ6	UPF0208 membrane protein
F9277_04360	ENOG4105C7J	ABC transporter, permease
F9277_04365	ENOG4108JJB	ABC transporter
F9277_04370	ENOG4107R28	alpha amylase, catalytic region
F9277_04375	ENOG4105BZU	Histidine kinase
F9277_04380	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
F9277_04385	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
F9277_04390	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
F9277_04395	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
F9277_04400	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
F9277_04410	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
F9277_04415	ENOG4105D1F	ATP-binding protein
F9277_04420	ENOG4105DBI	uridine monophosphokinase
F9277_04430	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
F9277_04440	ENOG4105CHH	sulfate transporter
F9277_04450	ENOG4105C03	ribonuclease
F9277_04455	ENOG4105EI2	Pseudouridine synthase
F9277_04460	ENOG4108UHJ	MAF-like protein
F9277_04465	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
F9277_04470	ENOG4105VGS	50s ribosomal protein l32
F9277_04475	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
F9277_04480	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
F9277_04485	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
F9277_04490	ENOG4105CHR	reductase
F9277_04495	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
F9277_04500	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F9277_04510	ENOG4105HHA	aminodeoxychorismate lyase
F9277_04515	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
F9277_04520	ENOG4107QRG	dna polymerase iii
F9277_04525	ENOG4105F8V	Hydrolase, tatD family
F9277_04530	ENOG4105CI1	PTS System
F9277_04545	ENOG4105C8J	)-transporter
F9277_04560	ENOG4108NRW	Phospholipase, patatin family
F9277_04565	ENOG4105CA9	Pyruvate kinase
F9277_04570	ENOG4105DAG	ROK family
F9277_04575	ENOG4107R88	Chemotaxis protein (CheV)
F9277_04580	ENOG4105C0B	DNA polymerase III (alpha subunit)
F9277_04595	ENOG4105UBK	short-chain dehydrogenase reductase
F9277_04600	ENOG4105ERU	peptidase
F9277_04605	ENOG4105CAT	Cytidine monophosphate kinase
F9277_04610	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
F9277_04615	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F9277_04620	ENOG4105Q4A	inner membrane protein yciS
F9277_04625	ENOG4105CFV	Tetratricopeptide repeat protein
F9277_04630	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
F9277_04635	ENOG4108J59	Extracellular solute-binding protein, family 5
F9277_04690	ENOG4108Q2G	(LipO)protein
F9277_04695	ENOG4105DY2	Paraquat-inducible protein b
F9277_04700	ENOG4105F1S	paraquat-inducible protein a
F9277_04705	ENOG4105JQN	Transcriptional regulator
F9277_04715	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
F9277_04720	ENOG4105N6Y	Thioredoxin
F9277_04730	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
F9277_04760	ENOG41080VW	acetyltransferase
F9277_04785	ENOG4107RBB	ABC transporter, permease
F9277_04795	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F9277_04825	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
F9277_04840	ENOG41090MY	MarR family Transcriptional regulator
F9277_04850	ENOG4105J12	Multidrug resistance protein mdtN
F9277_04855	ENOG4105EQ2	LysR family Transcriptional regulator
F9277_04875	ENOG41062D9	Histidine kinase
F9277_04880	ENOG4105ETX	regulatoR
F9277_04890	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
F9277_04900	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_04905	ENOG4105WWK	YheO domain protein
F9277_04910	ENOG4105KME	endoribonuclease L-psp
F9277_04915	ENOG4107R6U	sodium dicarboxylate symporter
F9277_04920	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
F9277_04945	ENOG4105CCT	upf0313 protein
F9277_04965	ENOG4105DZ2	Transcriptional regulator
F9277_04980	ENOG4105K9H	YciI-like protein
F9277_04985	ENOG4105NAU	thioesterase Superfamily protein
F9277_04990	ENOG4107835	probably involved in intracellular septation (By similarity)
F9277_05000	ENOG4105BZU	Histidine kinase
F9277_05010	ENOG4105CK2	sodium dicarboxylate symporter
F9277_05015	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
F9277_05020	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
F9277_05025	ENOG4105DK0	Indole-3-glycerol phosphate synthase
F9277_05030	ENOG4108I0Q	anthranilate phosphoribosyltransferase
F9277_05035	ENOG4105DDQ	anthranilate synthase
F9277_05040	ENOG4105CRQ	synthase (Component I)
F9277_05050	ENOG4105DB7	PHP domain protein
F9277_05055	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
F9277_05065	ENOG4105FE9	pseudouridine synthase
F9277_05070	ENOG4108W5H	UPF0263 protein
F9277_05165	ENOG4105C79	DNA protecting protein DprA
F9277_05175	ENOG4107TII	Recombinase
F9277_05180	ENOG4105CQ2	DNA polymerase
F9277_05185	ENOG4105WH1	Two component transcriptional regulator luxr family
F9277_05190	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
F9277_05235	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
F9277_05260	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F9277_05265	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F9277_05275	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
F9277_05280	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F9277_05295	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
F9277_05305	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
F9277_05310	ENOG4105DVI	reductase, NrfD
F9277_05315	ENOG4105DA4	cytochrome c-type biogenesis protein
F9277_05320	ENOG4107QX9	Thiol disulfide interChange protein
F9277_05325	ENOG4108DMF	Cytochrome C biogenesis protein
F9277_05335	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
F9277_05360	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
F9277_05365	ENOG4105EAQ	(twin-arginine translocation) pathway signal
F9277_05370	ENOG4105C5X	domain protein
F9277_05385	ENOG4105CH5	extracellular solute-binding protein, family 7
F9277_05395	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F9277_05410	ENOG41067TZ	transcriptional regulator, MarR family
F9277_05415	ENOG4105C94	Transporter
F9277_05420	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_05440	ENOG4105CGF	Aromatic amino acid aminotransferase
F9277_05445	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
F9277_05460	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F9277_05475	ENOG4105C5S	asparaginyl-tRNA synthetase
F9277_05480	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_05485	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
F9277_05490	ENOG4105WH1	Two component transcriptional regulator luxr family
F9277_05500	ENOG4105BZU	Histidine kinase
F9277_05505	ENOG4105EJQ	L-serine dehydratase
F9277_05510	ENOG4105C44	Serine transporter
F9277_05530	ENOG4105CRQ	synthase (Component I)
F9277_05545	ENOG4105CM6	amino acid regulated cytosolic protein
F9277_05550	ENOG4106K28	UPF0283 membrane protein
F9277_05560	ENOG4105D9U	N-acetyltransferase
F9277_05600	ENOG4106611	bacteriocin immunity
F9277_05765	ENOG4105K4H	Nlp p60 protein
F9277_05870	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
F9277_05880	ENOG4108K3A	Glutathione S-transferase
F9277_05920	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F9277_06435	ENOG4106611	bacteriocin immunity
F9277_06620	ENOG4105EC3	peptidase S51, dipeptidase E
F9277_06690	ENOG4105K4U	addiction module toxin, RelE StbE family
F9277_06845	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F9277_06890	ENOG4105C8V	SAICAR synthetase
F9277_06910	ENOG4105CDV	Ompa motb domain protein
F9277_06925	ENOG4105CQB	FAD linked oxidase domain protein
F9277_06940	ENOG4105C84	Histidine ammonia-lyase
F9277_06945	ENOG4105CGP	Urocanate hydratase
F9277_06950	ENOG41088SP	formiminoglutamate hydrolase
F9277_06955	ENOG4105CI2	imidazolone-5-propionate hydrolase
F9277_06960	ENOG4105CZE	histidine utilization repressor
F9277_06975	ENOG4105C22	threonyL-tRNA synthetase
F9277_06980	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
F9277_06985	ENOG41082NX	50s ribosomal protein l35
F9277_06990	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
F9277_06995	ENOG4105KME	endoribonuclease L-psp
F9277_07000	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
F9277_07005	ENOG4105K8R	UPF0145 protein
F9277_07040	ENOG4105BZU	Histidine kinase
F9277_07045	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
F9277_07050	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
F9277_07090	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
F9277_07100	ENOG4105FQ6	thiopurine methyltransferase
F9277_07105	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
F9277_07110	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
F9277_07115	ENOG41067MG	lrgb family
F9277_07120	ENOG4105VAW	lrga family
F9277_07125	ENOG4105CJB	Exodeoxyribonuclease I
F9277_07135	ENOG4108ETY	sodium dicarboxylate symporter
F9277_07140	ENOG4105K4T	epimerase
F9277_07145	ENOG4107XWI	flavin reductase domain protein, FMN-binding
F9277_07150	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
F9277_07155	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
F9277_07165	ENOG410902C	phosphohistidine phosphatase, SixA
F9277_07175	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
F9277_07180	ENOG4108IU2	vtamin B12-transporter permease
F9277_07185	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
F9277_07240	ENOG4105F04	LysR family Transcriptional regulator
F9277_07265	ENOG4108VAU	general secretion pathway protein G
F9277_07270	ENOG4108VKG	metal-dependent hydrolase
F9277_07275	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
F9277_07280	ENOG4105BZU	Histidine kinase
F9277_07300	ENOG4105CTU	Proline racemase
F9277_07305	ENOG41080HI	glycine oxidase
F9277_07315	ENOG4105CIF	Ornithine Cyclodeaminase
F9277_07320	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
F9277_07325	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F9277_07330	ENOG4105F38	ABC transporter, permease
F9277_07335	ENOG4105D38	putrescine abc transporter
F9277_07345	ENOG4108QW8	Purine nucleoside phosphorylase deoD-type
F9277_07365	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
F9277_07370	ENOG4105BZS	acriflavin resistance protein
F9277_07380	ENOG4105ETX	regulatoR
F9277_07400	ENOG4107MM9	BNR Asp-box repeat-containing protein
F9277_07415	ENOG4108JQ7	(ABC) transporter
F9277_07420	ENOG4105C3U	ABC transporter
F9277_07425	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F9277_07430	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
F9277_07435	ENOG4107QSI	ABC, transporter
F9277_07440	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
F9277_07450	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
F9277_07455	ENOG4105F1J	Homogentisate 1,2-dioxygenase
F9277_07465	ENOG4108RXX	maleylacetoacetate isomerase
F9277_07555	ENOG4108Z4K	mutator MutT protein
F9277_07570	ENOG4107QSI	ABC, transporter
F9277_07600	ENOG4106YYS	transcriptional regulatory protein
F9277_07605	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
F9277_07610	ENOG4105D9Q	decarboxylase (Beta subunit)
F9277_07615	ENOG4107QSA	Oxaloacetate decarboxylase
F9277_07630	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
F9277_07635	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
F9277_07640	ENOG4105CI0	Citrate lyase
F9277_07645	ENOG4105CHY	citrate lyase, alpha
F9277_07650	ENOG4105YGP	holo-ACP synthase CitX
F9277_07655	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
F9277_07685	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
F9277_07690	ENOG4105C26	Dehydrogenase
F9277_07695	ENOG4105BZG	amino acid carrier protein
F9277_07715	ENOG41063TF	transcriptional regulator (AraC
F9277_07730	ENOG4105E0M	Sulfatase
F9277_07735	ENOG4105C8N	cysteinyl-tRNA synthetase
F9277_07740	ENOG4107QI1	Mate efflux family protein
F9277_07745	ENOG41080XQ	Signal transduction protein with cbs domains
F9277_07755	ENOG4105C94	Transporter
F9277_07760	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
F9277_07765	ENOG4108JPW	Aminotransferase
F9277_07770	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
F9277_07775	ENOG4105CZK	Aspartate kinase
F9277_07790	ENOG4105CA0	peroxidase
F9277_07795	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
F9277_07800	ENOG4105HEI	LysR family (Transcriptional regulator
F9277_07805	ENOG4105ECR	NmrA family
F9277_07820	ENOG4107YCY	Transcriptional regulator
F9277_07860	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
F9277_07865	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
F9277_07875	ENOG4105F27	Major Facilitator
F9277_07880	ENOG4105HEI	LysR family (Transcriptional regulator
F9277_07905	ENOG4107V40	secretion protein, HlyD family
F9277_07920	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
F9277_07925	ENOG4108V9W	transcriptional regulatory protein
F9277_07930	ENOG4105E0K	tonB-dependent siderophore receptor
F9277_07935	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
F9277_07940	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
F9277_07945	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
F9277_07950	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
F9277_07955	ENOG4105Q9Y	Universal stress protein
F9277_07965	ENOG4105KXC	Collagenase
F9277_07975	ENOG4106R3P	AraC family transcriptional regulator
F9277_08050	ENOG4105CDV	Ompa motb domain protein
F9277_08060	ENOG4107QHE	Choloylglycine hydrolase
F9277_08070	ENOG4105CUY	Mechanosensitive ion channel
F9277_08075	ENOG4108YK4	Acid-resistance membrane protein
F9277_08085	ENOG4108ZT1	Transcriptional regulator
F9277_08110	ENOG4108UW5	maltose o-acetyltransferase
F9277_08125	ENOG4105BZU	Histidine kinase
F9277_08130	ENOG4105BZU	Histidine kinase
F9277_08135	ENOG4105CDV	Ompa motb domain protein
F9277_08150	ENOG4105DR4	Methyltransferase
F9277_08155	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_08160	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
F9277_08165	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
F9277_08170	ENOG4108MN8	Membrane
F9277_08175	ENOG4105CDA	abc transporter atp-binding protein
F9277_08180	ENOG4105DRP	amino acid AbC transporter
F9277_08185	ENOG4105EZ7	amino acid ABC transporter
F9277_08190	ENOG4107QXX	ABC transporter
F9277_08205	ENOG4108VPT	UPF0234 protein
F9277_08210	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
F9277_08230	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
F9277_08235	ENOG4105DY2	Paraquat-inducible protein b
F9277_08240	ENOG4105H2K	paraquat-inducible protein a
F9277_08245	ENOG4105BZ1	(ABC) transporter
F9277_08250	ENOG4108ZGC	gaf domain protein
F9277_08255	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
F9277_08260	ENOG4105CN1	protease
F9277_08270	ENOG4105CD8	aminopeptidase N
F9277_08280	ENOG4105C7I	Dehydrogenase
F9277_08290	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
F9277_08295	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
F9277_08300	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
F9277_08310	ENOG4105C5H	ABC transporter
F9277_08325	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
F9277_08330	ENOG4105DAN	ATP-dependent protease
F9277_08335	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
F9277_08360	ENOG4105BZU	Histidine kinase
F9277_08375	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
F9277_08390	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
F9277_08400	ENOG4105C59	p-type ATPase
F9277_08415	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
F9277_08420	ENOG4105Q9Y	Universal stress protein
F9277_08425	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
F9277_08435	ENOG4108UR8	BAX protein
F9277_08445	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F9277_08450	ENOG4105F38	ABC transporter, permease
F9277_08455	ENOG4105D38	putrescine abc transporter
F9277_08460	ENOG4107RUE	extracellular solute-binding protein family 1
F9277_08465	ENOG4107RUE	extracellular solute-binding protein family 1
F9277_08470	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
F9277_08490	ENOG4105QAX	Iron-sulfur
F9277_08495	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
F9277_08505	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
F9277_08525	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
F9277_08530	ENOG4105C5H	ABC transporter
F9277_08550	ENOG4105BZU	Histidine kinase
F9277_08555	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_08565	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
F9277_08570	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F9277_08575	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
F9277_08580	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
F9277_08590	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
F9277_08595	ENOG4106IUH	DTW domain containing protein
F9277_08640	ENOG4108N3W	hemolysin secretion protein
F9277_08645	ENOG4107TT5	NLP P60 protein
F9277_08710	ENOG41075IY	surface presentation of antigens protein SpaP
F9277_08725	ENOG4108DQ1	activator toxR
F9277_08755	ENOG4105D00	flagellar biosynthetic protein flhB
F9277_08830	ENOG4105PWE	CRISPR-associated protein cas2
F9277_08835	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
F9277_08845	ENOG4108VWQ	crispr-associated protein
F9277_08865	ENOG4105DTT	CRISPR-associated helicase, cas3
F9277_08905	ENOG4105CEE	C4-dicarboxylate transporter
F9277_08910	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
F9277_08930	ENOG4105UYK	outer membrane protein a
F9277_08935	ENOG4107VGF	ig domain protein group 2 domain protein
F9277_08955	ENOG4108YGG	dna repair protein
F9277_08995	ENOG4105FDP	GntR family transcriptional regulator
F9277_09025	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F9277_09030	ENOG4105C4X	radical SAM domain protein
F9277_09035	ENOG41061MV	Arylsulfatase
F9277_09045	ENOG4105CPQ	Dehydrogenase
F9277_09050	ENOG4105C5I	Dehydrogenase
F9277_09055	ENOG4105CMG	Carbohydrate kinase
F9277_09065	ENOG4105C0A	alcohol dehydrogenase
F9277_09070	ENOG4108J1Q	
F9277_09140	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
F9277_09155	ENOG4108YGG	dna repair protein
F9277_09185	ENOG4105BZU	Histidine kinase
F9277_09190	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
F9277_09195	ENOG4105FGM	Fructosamine kinase
F9277_09205	ENOG4108R6K	riboflavin synthase, subunit alpha
F9277_09210	ENOG4107QI1	Mate efflux family protein
F9277_09225	ENOG41082AN	stage II sporulation protein
F9277_09235	ENOG4107V1M	polysaccharide export protein
F9277_09250	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_09260	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
F9277_09290	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
F9277_09310	ENOG4105F88	accessory colonization factor AcfD
F9277_09330	ENOG4105CDV	Ompa motb domain protein
F9277_09340	ENOG410620I	Diguanylate cyclase
F9277_09345	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
F9277_09350	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
F9277_09355	ENOG410667J	hydrolase
F9277_09365	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
F9277_09375	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F9277_09380	ENOG4105C7F	AcnD-accessory protein PrpF
F9277_09385	ENOG4108I0Z	Aconitate hydratase
F9277_09390	ENOG4105BZN	citrate synthase
F9277_09395	ENOG4105CR4	methylisocitrate lyase
F9277_09410	ENOG4105CS6	Rhs element vgr protein
F9277_09465	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F9277_09505	ENOG4108ESY	Metal dependent phosphohydrolase
F9277_09515	ENOG4105KD7	acetyltransferase
F9277_09540	ENOG4105EJ9	Membrane
F9277_09550	ENOG4105BZS	acriflavin resistance protein
F9277_09565	ENOG410829K	Lysine exporter protein (Lyse ygga)
F9277_09600	ENOG4105WH1	Two component transcriptional regulator luxr family
F9277_09605	ENOG4105CTD	carboxy-peptidase
F9277_09615	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
F9277_09630	ENOG4105D1S	lipid A biosynthesis
F9277_09635	ENOG4105HEI	LysR family (Transcriptional regulator
F9277_09640	ENOG4105N14	lysine exporter protein LysE YggA
F9277_09645	ENOG4105E5D	amino acid
F9277_09665	ENOG4105CVG	Homoserine O-transsuccinylase
F9277_09670	ENOG41090FY	type IV pilus biogenesis stability protein PilW
F9277_09695	ENOG4105CQ7	ATP-dependent helicase
F9277_09700	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
F9277_09710	ENOG4108NEM	leader-binding protein dmsD
F9277_09715	ENOG4107KGK	dmso reductase anchor subunit
F9277_09720	ENOG4105QAX	Iron-sulfur
F9277_09725	ENOG4107QY8	reductase
F9277_09755	ENOG4105BZU	Histidine kinase
F9277_09765	ENOG4105CFG	Acts as a chaperone (By similarity)
F9277_09770	ENOG4105CFG	Acts as a chaperone (By similarity)
F9277_09795	ENOG4105CR8	Transcriptional regulator
F9277_09810	ENOG4105BZ1	(ABC) transporter
F9277_09815	ENOG4105BZ1	(ABC) transporter
F9277_09830	ENOG4105E0K	tonB-dependent siderophore receptor
F9277_09835	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
F9277_09840	ENOG4105J76	Periplasmic binding protein
F9277_09845	ENOG4105E0A	ABC, transporter
F9277_09860	ENOG4105E0U	tyrosine-specific transport protein
F9277_09865	ENOG4105C0A	alcohol dehydrogenase
F9277_09875	ENOG4105DHT	Metal Dependent Phosphohydrolase
F9277_09885	ENOG4105EE5	Membrane protein terC
F9277_09895	ENOG41076CZ	activating enzyme
F9277_09900	ENOG4105G0K	glycine radical enzyme YjjI family
F9277_09910	ENOG4105CPI	Metal Dependent Phosphohydrolase
F9277_09915	ENOG4105BZU	Histidine kinase
F9277_09920	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_09925	ENOG4105BZU	Histidine kinase
F9277_09930	ENOG4105C8P	)-transporter
F9277_09975	ENOG4105CQ7	ATP-dependent helicase
F9277_09980	ENOG4107R1I	NAD-dependent malic enzyme
F9277_09985	ENOG4107GZ4	SanA protein
F9277_09990	ENOG4105C8P	)-transporter
F9277_09995	ENOG4105BZU	Histidine kinase
F9277_10015	ENOG4105C3M	thioredoxin reductase
F9277_10020	ENOG4108JJ9	ABC, transporter
F9277_10025	ENOG4108JJ8	(ABC) transporter
F9277_10030	ENOG4105BZC	d-serine deaminase
F9277_10040	ENOG4105W8I	Transcriptional regulator
F9277_10060	ENOG4105BZU	Histidine kinase
F9277_10070	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
F9277_10080	ENOG4105BZU	Histidine kinase
F9277_10110	ENOG4105DWU	Membrane
F9277_10120	ENOG4105DY8	decarboxylase
F9277_10125	ENOG4106KNT	transcriptional regulator
F9277_10135	ENOG41090BQ	Glutaredoxin
F9277_10140	ENOG4105D0C	transport protein
F9277_10145	ENOG4105RKW	reductase (By
F9277_10150	ENOG4107QPN	acyl-Coa dehydrogenase
F9277_10155	ENOG41067SE	Tetr family transcriptional regulator
F9277_10160	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
F9277_10175	ENOG4108I0Y	(ABC) transporter
F9277_10180	ENOG4107QI1	Mate efflux family protein
F9277_10185	ENOG4105CGD	Nad-dependent epimerase dehydratase
F9277_10190	ENOG4105ETE	Transcriptional regulator (LacI family
F9277_10200	ENOG4107RUZ	Sss sodium solute transporter superfamily
F9277_10210	ENOG4105C2C	drug resistance transporter, Bcr CflA
F9277_10215	ENOG4105I08	Pseudouridine synthase
F9277_10220	ENOG4105CFI	type iii restriction protein res subunit
F9277_10230	ENOG4105ETX	regulatoR
F9277_10235	ENOG4105E0F	Histidine kinase
F9277_10250	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
F9277_10265	ENOG4105CGH	5'-nucleotidase
F9277_10275	ENOG4105XZD	Fe-S protein
F9277_10285	ENOG4105CHH	sulfate transporter
F9277_10295	ENOG4108ZXC	Two component transcriptional regulator, luxr family
F9277_10300	ENOG4106AFQ	Histidine kinase
F9277_10310	ENOG4105BZ8	glutamate synthase
F9277_10320	ENOG4108RSN	SNARE associated Golgi
F9277_10325	ENOG4105VNH	ABC transporter solute-binding protein
F9277_10330	ENOG4105CXZ	ABC transporter, permease
F9277_10335	ENOG4108VGW	abc transporter atp-binding protein
F9277_10340	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
F9277_10345	ENOG4108JUA	Transcriptional regulator
F9277_10350	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
F9277_10355	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
F9277_10365	ENOG4108W1A	pseudouridine synthase
F9277_10375	ENOG4105C8J	)-transporter
F9277_10385	ENOG4105C28	cystathionine
F9277_10390	ENOG4107IFA	Lipase (EC 3.1.1.3)
F9277_10400	ENOG4108R3E	Dna-3-methyladenine glycosylase i
F9277_10425	ENOG4105YYT	phage shock protein B
F9277_10430	ENOG41087YS	Phage shock protein A
F9277_10435	ENOG4105E51	psp operon transcriptional activator
F9277_10440	ENOG4108J59	Extracellular solute-binding protein, family 5
F9277_10445	ENOG4108I5W	peptide transport system, permease protein
F9277_10450	ENOG4108EU3	peptide transport system, permease
F9277_10455	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
F9277_10460	ENOG4108JQ2	peptide transport system atp-binding protein
F9277_10470	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
F9277_10475	ENOG4105CC5	ABC transporter
F9277_10480	ENOG4105CC5	ABC transporter
F9277_10485	ENOG4105DIK	(ABC) transporter
F9277_10500	ENOG4108J2R	molybdopterin oxidoreductase
F9277_10520	ENOG4105TMB	Formate nitrite transporter
F9277_10545	ENOG4105GFG	DUF218 domain
F9277_10550	ENOG4107104	thymidine kinase
F9277_10555	ENOG4105C8N	cysteinyl-tRNA synthetase
F9277_10560	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
F9277_10565	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
F9277_10570	ENOG4105D58	Diguanylate phosphodiesterase
F9277_10575	ENOG4105K5B	UPF0225 protein
F9277_10600	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
F9277_10605	ENOG4105CIH	Imidazole acetol-phosphate transaminase
F9277_10610	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
F9277_10615	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
F9277_10620	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_10625	ENOG4107S6Z	Na H antiporter
F9277_10630	ENOG4108YX2	DNA-binding protein
F9277_10635	ENOG4107RE1	Inosine-guanosine kinase
F9277_10645	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
F9277_10650	ENOG41075W9	High frequency lysogenization protein HflD homolog
F9277_10655	ENOG4107QTF	adenylosuccinate lyase
F9277_10665	ENOG4105RHG	
F9277_10675	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
F9277_10690	ENOG4107FW0	short-chain dehydrogenase reductase
F9277_10700	ENOG4105D0M	Protease HtpX homolog
F9277_10710	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
F9277_10720	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F9277_10725	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
F9277_10735	ENOG4105KSC	Transcriptional regulator, TraR DksA family
F9277_10750	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
F9277_10755	ENOG4105D1H	recombination factor protein RarA
F9277_10760	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
F9277_10765	ENOG4105CNU	cell division protein FtsK
F9277_10770	ENOG4105EW9	transcriptional regulator AsnC family
F9277_10775	ENOG4105DCF	alanine dehydrogenase
F9277_10785	ENOG4107R11	Transcriptional regulator
F9277_10795	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
F9277_10810	ENOG4105KXC	Collagenase
F9277_10815	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_10845	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
F9277_10860	ENOG4105CK7	Sodium proline symporter
F9277_10865	ENOG4108UHU	Aldolase
F9277_10870	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
F9277_10875	ENOG4105M5J	Cupin 2, conserved barrel domain protein
F9277_10880	ENOG4105EY3	heparinase II III family protein
F9277_10885	ENOG4105EY3	heparinase II III family protein
F9277_10895	ENOG4107EJG	GntR family transcriptional regulator
F9277_10900	ENOG4105CHR	reductase
F9277_10905	ENOG4107EJG	GntR family transcriptional regulator
F9277_10910	ENOG41080XP	Cbs domain
F9277_10915	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
F9277_10935	ENOG4107RJ1	sodium solute
F9277_10950	ENOG4105ERH	Fumarylacetoacetate hydrolase
F9277_10970	ENOG4105JXH	GntR family transcriptional regulator
F9277_10980	ENOG4105BZS	acriflavin resistance protein
F9277_10985	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
F9277_11000	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_11020	ENOG4105IJJ	transcriptional regulator, crp fnr family
F9277_11035	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
F9277_11040	ENOG4108HKT	sucrose-6-phosphate hydrolase
F9277_11045	ENOG4105D7K	pfkb domain protein
F9277_11050	ENOG4105C5Y	PTS System
F9277_11065	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
F9277_11070	ENOG4105W1Y	Transcriptional regulator
F9277_11235	ENOG41066XE	Type III export protein
F9277_11265	ENOG4108KB1	transcriptional regulator, arac family
F9277_11290	ENOG4108RNS	Exports L-alanine (By similarity)
F9277_11295	ENOG4105BZU	Histidine kinase
F9277_11305	ENOG4106032	Glutathionylspermidine synthase
F9277_11315	ENOG4105Z6B	inner membrane protein yjfl
F9277_11325	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
F9277_11330	ENOG4105EIP	mannose-6-phosphate isomerase
F9277_11335	ENOG4105EVE	HAD-superfamily hydrolase subfamily IA variant 3
F9277_11340	ENOG4105DCT	glycerol dehydrogenase
F9277_11345	ENOG4106R3P	AraC family transcriptional regulator
F9277_11350	ENOG4108XCZ	PTS System
F9277_11355	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
F9277_11360	ENOG4105EXW	epimerase dehydratase
F9277_11365	ENOG4108AHH	pyruvate formate lyase II activase
F9277_11370	ENOG4105C6N	Formate acetyltransferase
F9277_11375	ENOG4108YRF	PTS System
F9277_11380	ENOG4105DM4	PTS System
F9277_11385	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
F9277_11390	ENOG4105D9R	oxidoreductase
F9277_11395	ENOG41090KN	UPF0303 protein
F9277_11400	ENOG4105C2X	Arabinose 5-phosphate isomerase
F9277_11405	ENOG4105UFD	tol-pal system protein YbgF
F9277_11410	ENOG4105KCK	Peptidoglycan-associated lipoprotein
F9277_11415	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
F9277_11425	ENOG4105M8F	Biopolymer transport protein exbD tolR
F9277_11430	ENOG4105E02	MotA TolQ exbB proton channel
F9277_11435	ENOG4107YD3	Thioesterase
F9277_11450	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
F9277_11455	ENOG4105C4M	(Ubiquinol oxidase) subunit I
F9277_11460	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
F9277_11465	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
F9277_11470	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_11475	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
F9277_11480	ENOG4105C9M	aspartyl-trna synthetase
F9277_11485	ENOG41081XQ	Conserved Protein
F9277_11490	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
F9277_11495	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
F9277_11505	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F9277_11515	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F9277_11525	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
F9277_11530	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
F9277_11535	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
F9277_11540	ENOG4106371	Methyltransferase
F9277_11545	ENOG4107S90	membrAne
F9277_11550	ENOG4106WF9	DNA-binding transcriptional regulator TorR
F9277_11555	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
F9277_11560	ENOG4105ETE	Transcriptional regulator (LacI family
F9277_11565	ENOG4105HP8	regulator of competence-specific genes
F9277_11585	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
F9277_11590	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
F9277_11595	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
F9277_11600	ENOG4105RKX	Protein of unknown function (DUF2498)
F9277_11605	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
F9277_11615	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
F9277_11620	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
F9277_11625	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
F9277_11630	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F9277_11635	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
F9277_11640	ENOG4105VEQ	Cold shock protein
F9277_11650	ENOG4108R99	pseudouridine synthase
F9277_11665	ENOG4105DVT	helicase
F9277_11670	ENOG4105EJ9	Membrane
F9277_11680	ENOG4106428	Protein of unknown function (DUF2496)
F9277_11685	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_11690	ENOG4105CGK	Exodeoxyribonuclease III
F9277_11700	ENOG4105DSP	amino acid AbC transporter
F9277_11705	ENOG4105E89	ABC transporter
F9277_11710	ENOG4108JEH	abc transporter atp-binding protein
F9277_11730	ENOG4105C6N	Formate acetyltransferase
F9277_11740	ENOG4105F1A	Pyruvate formate-lyase
F9277_11750	ENOG4105XWI	UPF0304 protein
F9277_11760	ENOG4105CYN	Serine protein kinase
F9277_11765	ENOG4106AKX	UPF0229 protein
F9277_11770	ENOG4105ED1	spovr family
F9277_11775	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
F9277_11780	ENOG4105W49	UPF0434 protein
F9277_11785	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
F9277_11790	ENOG4105BZ1	(ABC) transporter
F9277_11795	ENOG4108EC8	DNA internalization-related competence protein ComEC
F9277_11805	ENOG4105D60	lipoprotein releasing system transmembrane protein
F9277_11810	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
F9277_11815	ENOG4105D60	lipoprotein releasing system transmembrane protein
F9277_11825	ENOG4108JA2	transcriptioN-repair coupling factor
F9277_11840	ENOG4105CEP	NADH dehydrogenase
F9277_11845	ENOG4105D0Y	UPF0227 protein
F9277_11870	ENOG4105K59	histidine triad (HIT) protein
F9277_11875	ENOG4108NVR	Methyl-accepting chemotaxis
F9277_11885	ENOG4107SXA	Phosphorylase
F9277_11890	ENOG4105C59	p-type ATPase
F9277_11900	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F9277_11905	ENOG4105DZ0	fad dependent oxidoreductase
F9277_11910	ENOG4108Z4U	Ferredoxin
F9277_11930	ENOG4105BZU	Histidine kinase
F9277_11945	ENOG4108MNP	Glycoprotein polysaccharide metabolism
F9277_11950	ENOG4105C29	acyl-CoA thioesterase
F9277_11960	ENOG4108XM1	transcriptional regulator AsnC family
F9277_11985	ENOG4105BZS	acriflavin resistance protein
F9277_12035	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
F9277_12040	ENOG4105HMI	Membrane
F9277_12060	ENOG4105CI1	PTS System
F9277_12065	ENOG4105CEY	Amp-dependent synthetase and ligase
F9277_12070	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
F9277_12075	ENOG4108IPT	Naphthoate synthase
F9277_12080	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
F9277_12085	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
F9277_12090	ENOG4105E4F	Isochorismate synthase
F9277_12095	ENOG4105CHM	Aminotransferase
F9277_12100	ENOG4105DK2	UPF0207 protein
F9277_12105	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
F9277_12125	ENOG4105EIN	peptidylprolyl cis-trans isomerase
F9277_12130	ENOG4105K70	DNA-binding protein
F9277_12135	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
F9277_12140	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
F9277_12145	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
F9277_12150	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
F9277_12165	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_12175	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F9277_12180	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
F9277_12185	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
F9277_12190	ENOG4105CNG	UPF0061 protein
F9277_12205	ENOG4107ZYR	domain protein
F9277_12210	ENOG4105C1J	atp-dependent rna helicase
F9277_12220	ENOG4105D05	Receptor
F9277_12235	ENOG4105CEY	Amp-dependent synthetase and ligase
F9277_12235	ENOG4105CEY	Amp-dependent synthetase and ligase
F9277_12240	ENOG4105WQI	isochorismatase
F9277_12245	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
F9277_12250	ENOG4105E4F	Isochorismate synthase
F9277_12260	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
F9277_12300	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
F9277_12320	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
F9277_12325	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
F9277_12330	ENOG4105C84	Histidine ammonia-lyase
F9277_12360	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
F9277_12365	ENOG4105C2D	reductase
F9277_12370	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
F9277_12385	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
F9277_12395	ENOG4105DVF	Cytosine-specific methyltransferase
F9277_12400	ENOG4105D9N	nucleoside
F9277_12405	ENOG4105EQ2	LysR family Transcriptional regulator
F9277_12410	ENOG4105CVE	Lytic murein transglycosylase
F9277_12415	ENOG4105VNG	YcgL domain-containing protein
F9277_12420	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
F9277_12425	ENOG4107QMS	site-determining protein
F9277_12430	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
F9277_12435	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
F9277_12440	ENOG4105CEY	Amp-dependent synthetase and ligase
F9277_12445	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
F9277_12450	ENOG4105R8X	Outer membrane lipoprotein Slp
F9277_12460	ENOG41072GX	Peptidase M22 Glycoprotease
F9277_12465	ENOG4105DVT	helicase
F9277_12470	ENOG4105CIY	formyltetrahydrofolate deformylase
F9277_12475	ENOG4106ZCM	YecM protein
F9277_12485	ENOG4105C75	arginyL-tRNA synthetase
F9277_12510	ENOG4105XFK	Ferrous iron transport protein A
F9277_12515	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
F9277_12520	ENOG4105NXV	High-affinity zinc uptake system protein
F9277_12525	ENOG4105FDK	ABC transporter
F9277_12530	ENOG4105FAV	ABC, transporter
F9277_12535	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
F9277_12540	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
F9277_12545	ENOG4105C7S	Dehydrogenase
F9277_12550	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
F9277_12555	ENOG4105E33	succinate dehydrogenase
F9277_12560	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
F9277_12565	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
F9277_12570	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
F9277_12575	ENOG4105BZN	citrate synthase
F9277_12580	ENOG4107QNR	UPF0135 protein
F9277_12595	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
F9277_12600	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
F9277_12605	ENOG4105EV9	Alpha Beta Hydrolase
F9277_12615	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
F9277_12625	ENOG41090R7	Ferric uptake
F9277_12630	ENOG4108VAU	general secretion pathway protein G
F9277_12635	ENOG4105CX6	glutaminyL-tRNA synthetase
F9277_12640	ENOG4105CI1	PTS System
F9277_12650	ENOG4105CE4	GlcNAc 6-P deacetylase
F9277_12655	ENOG4105E2R	ROK family
F9277_12660	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
F9277_12665	ENOG4105CAQ	asparagine synthetase
F9277_12670	ENOG4105MDZ	Transcriptional activator rfaH
F9277_12675	ENOG4105DUX	Transporter
F9277_12680	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
F9277_12685	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
F9277_12690	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
F9277_12695	ENOG4108DQ1	activator toxR
F9277_12715	ENOG4108RE9	Phosphodiesterase
F9277_12745	ENOG4105ECP	epimerase
F9277_12750	ENOG4105E1F	short-chain dehydrogenase reductase
F9277_12760	ENOG4107QR8	Thioredoxin
F9277_12765	ENOG4107QX8	SPFH domain, Band 7 family protein
F9277_12790	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
F9277_12800	ENOG4105EXN	Sulfate transport protein CysZ
F9277_12805	ENOG4105C6T	cysteine synthase
F9277_12815	ENOG4105KZ7	phosphocarrier protein hpr
F9277_12820	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
F9277_12825	ENOG4105C5Y	PTS System
F9277_12835	ENOG4105I03	Flagellin
F9277_12840	ENOG4105I03	Flagellin
F9277_12855	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
F9277_12860	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
F9277_12865	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
F9277_12870	ENOG4105CGA	flagellar basal-body rod protein FlgG
F9277_12875	ENOG4108KPB	Flagellar basal-body rod protein FlgF
F9277_12885	ENOG4105BZE	flagellar hook protein, FlgE
F9277_12890	ENOG4105W00	Flagellar hook capping protein
F9277_12895	ENOG4108ZC9	flagellar basal-body rod protein flgc
F9277_12900	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
F9277_12905	ENOG4105BZU	Histidine kinase
F9277_12910	ENOG4107R88	Chemotaxis protein (CheV)
F9277_12955	ENOG4105UYK	outer membrane protein a
F9277_12960	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
F9277_12970	ENOG41081QG	Porin Gram-negative type
F9277_12980	ENOG4105C59	p-type ATPase
F9277_12995	ENOG4105E2D	ec 3.2.1.52
F9277_13025	ENOG4108DG9	Smr protein MutS2
F9277_13030	ENOG4105FE9	pseudouridine synthase
F9277_13035	ENOG4108Z66	YbaK ebsC protein
F9277_13040	ENOG4105CGH	5'-nucleotidase
F9277_13045	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
F9277_13050	ENOG41063JG	Transcriptional regulator
F9277_13055	ENOG4108YY7	Invasion gene expression up-regulator SirB
F9277_13060	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
F9277_13065	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
F9277_13070	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
F9277_13080	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
F9277_13085	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
F9277_13090	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
F9277_13095	ENOG4105C3G	gtp-binding protein
F9277_13210	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
F9277_13220	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
F9277_13225	ENOG4105C9A	Phoh family
F9277_13230	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
F9277_13235	ENOG4108JU5	Magnesium and cobalt efflux protein
F9277_13240	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
F9277_13245	ENOG4107PAI	alpha helical protein
F9277_13250	ENOG4105C8T	Leucyl-tRNA synthetase
F9277_13255	ENOG4108U2H	Rare lipoprotein B
F9277_13260	ENOG4105DJF	DNA polymerase III, delta' subunit
F9277_13265	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
F9277_13270	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
F9277_13275	ENOG4105CJN	penicillin-binding protein
F9277_13280	ENOG4105CNI	cell division protein FtsW
F9277_13285	ENOG4105K6T	rare lipoprotein A
F9277_13290	ENOG4105DZ1	carboxypeptidase
F9277_13295	ENOG4108Z43	UPF0250 protein
F9277_13300	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
F9277_13305	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
F9277_13310	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
F9277_13315	ENOG4108JYZ	YitT family
F9277_13330	ENOG4105CG3	alpha amylase, catalytic region
F9277_13335	ENOG4105C5Y	PTS System
F9277_13340	ENOG4105D4X	repressor
F9277_13345	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
F9277_13350	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
F9277_13355	ENOG4108UMI	ABC transporter, permease
F9277_13360	ENOG4105D01	(LipO)protein
F9277_13370	ENOG4105CGH	5'-nucleotidase
F9277_13375	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
F9277_13380	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
F9277_13385	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
F9277_13395	ENOG4105BZU	Histidine kinase
F9277_13400	ENOG4105EWT	decarboxylase family
F9277_13405	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
F9277_13415	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
F9277_13420	ENOG4105M08	Membrane
F9277_13430	ENOG4105ETT	transcriptional Regulator, LysR family
F9277_13435	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
F9277_13440	ENOG4106VK6	Flagellar motor protein
F9277_13440	ENOG4106VK6	Flagellar motor protein
F9277_13445	ENOG4105E14	MotA TolQ exbB proton channel
F9277_13450	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
F9277_13455	ENOG4105CTB	Polyprenyl synthetase
F9277_13460	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
F9277_13465	ENOG4108ZAI	phosphatidylglycerophosphatase a
F9277_13470	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
F9277_13475	ENOG4107YIM	Involved in the transcription termination process (By similarity)
F9277_13480	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
F9277_13495	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
F9277_13500	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
F9277_13505	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
F9277_13510	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
F9277_13515	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
F9277_13520	ENOG4108DJV	Fermentation respiration switch protein
F9277_13525	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
F9277_13530	ENOG4105C7N	Xanthine uracil vitamin C permease
F9277_13535	ENOG4105CIN	aminoacyl-histidine dipeptidase
F9277_13565	ENOG4108ETH	Formylglycinamide ribotide synthetase
F9277_13575	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
F9277_13585	ENOG4108Z6B	deaminase
F9277_13590	ENOG4105CFC	Transporter
F9277_13625	ENOG4105CFG	Acts as a chaperone (By similarity)
F9277_13635	ENOG4107QJT	sodium dicarboxylate symporter
F9277_13640	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F9277_13645	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
F9277_13655	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
F9277_13660	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F9277_13665	ENOG4105VDB	UPF0125 protein
F9277_13670	ENOG4108Z1B	Cyclase dehydrase
F9277_13675	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
F9277_13685	ENOG4105ETT	transcriptional Regulator, LysR family
F9277_13690	ENOG410613R	integral membrane protein, YccS YhfK family
F9277_13710	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
F9277_13730	ENOG4105JRK	feS assembly protein SufD
F9277_13735	ENOG4105C3K	feS assembly ATPase SufC
F9277_13740	ENOG4105DIW	FeS assembly protein SUFB
F9277_13745	ENOG4108Z4V	iron-sulfur cluster assembly
F9277_13750	ENOG4108IQK	o-acetylhomoserine
F9277_13765	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
F9277_13770	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
F9277_13775	ENOG4105BZG	amino acid carrier protein
F9277_13780	ENOG4106HK8	GPR1 FUN34 yaaH family protein
F9277_13790	ENOG4107S6Z	Na H antiporter
F9277_13795	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
F9277_13800	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F9277_13805	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
F9277_13815	ENOG410620I	Diguanylate cyclase
F9277_13825	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
F9277_13830	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
F9277_13835	ENOG4105N21	Membrane
F9277_13840	ENOG4105CUT	histidyl-tRNA synthetase
F9277_13845	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
F9277_13855	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
F9277_13860	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
F9277_13865	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
F9277_13870	ENOG4105WVQ	Fe-S assembly protein IscX
F9277_13875	ENOG4108ZIT	Ferredoxin, 2FE-2S
F9277_13880	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
F9277_13885	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
F9277_13890	ENOG4108Z4V	iron-sulfur cluster assembly
F9277_13895	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
F9277_13900	ENOG4105C3J	Cysteine desulfurase
F9277_13905	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
F9277_13910	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
F9277_13915	ENOG4105ECY	inositol monophosphatase
F9277_13930	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F9277_13935	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F9277_13940	ENOG4105VIE	preprotein translocase, subunit YajC
F9277_13945	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
F9277_13950	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
F9277_13965	ENOG4105W87	Cbs domain
F9277_13970	ENOG4108I9X	Isocitrate lyase
F9277_13975	ENOG4107QP3	malate synthase g
F9277_13980	ENOG4105C5Q	Transcriptional regulator
F9277_13985	ENOG4105D3R	alkyl hydroperoxide reductase
F9277_13990	ENOG4106N3A	copper homeostasis protein cutc
F9277_13995	ENOG4105CSR	polyphosphate kinase 2
F9277_14020	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
F9277_14025	ENOG4105E2Z	phosphate ABC transporter (Permease
F9277_14030	ENOG4105C8U	phosphate abc transporter
F9277_14035	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
F9277_14040	ENOG4105C9X	ppx gppa phosphatase
F9277_14050	ENOG4105BZU	Histidine kinase
F9277_14055	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F9277_14060	ENOG4105DH7	May be involved in recombination (By similarity)
F9277_14065	ENOG4105CFP	Peptidase U32
F9277_14070	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
F9277_14080	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
F9277_14135	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F9277_14140	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
F9277_14145	ENOG4105C34	Pseudouridine synthase
F9277_14150	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9277_14155	ENOG4105E4C	Lytic transglycosylase catalytic
F9277_14160	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
F9277_14170	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
F9277_14175	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
F9277_14180	ENOG4107SC1	transglycosylase
F9277_14185	ENOG4105C5H	ABC transporter
F9277_14195	ENOG4105DR5	peptidase
F9277_14200	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
F9277_14205	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
F9277_14210	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
F9277_14215	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
F9277_14220	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
F9277_14240	ENOG4108HRK	Histidine kinase
F9277_14245	ENOG4108NEV	two component transcriptional regulator, LytTR family
F9277_14250	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
F9277_14255	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
F9277_14260	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
F9277_14265	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
F9277_14270	ENOG4105DTN	riboflavin biosynthesis protein ribF
F9277_14275	ENOG4105CJR	Integral membrane protein (MviN
F9277_14280	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
F9277_14285	ENOG41080HT	Transcriptional regulator, arsr family
F9277_14290	ENOG41063Z6	transcriptional regulator, lysR family
F9277_14300	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
F9277_14305	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
F9277_14310	ENOG4105HF0	Membrane
F9277_14315	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
F9277_14320	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
F9277_14325	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
F9277_14335	ENOG4105CPC	Aldo Keto reductase
F9277_14345	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_14350	ENOG4105CRK	lysyL-tRNA synthetase
F9277_14360	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
F9277_14365	ENOG4105T95	Thiol disulfide interChange protein
F9277_14370	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F9277_14375	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
F9277_14380	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
F9277_14385	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
F9277_14390	ENOG4105C1J	atp-dependent rna helicase
F9277_14400	ENOG4105D1Q	UPF0246 protein
F9277_14465	ENOG4108R4U	Hnh endonuclease
F9277_14505	ENOG4105BZG	amino acid carrier protein
F9277_14520	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
F9277_14530	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
F9277_14535	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
F9277_14540	ENOG4108YYH	Nadph-dependent fmn reductase
F9277_14545	ENOG4105D98	threonine synthase
F9277_14550	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
F9277_14565	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
F9277_14580	ENOG41065U4	response regulator
F9277_14590	ENOG4105BZU	Histidine kinase
F9277_14605	ENOG4105N5T	Radical SAM Protein
F9277_14620	ENOG4105CBC	glutamate synthase
F9277_14625	ENOG4105BZ8	glutamate synthase
F9277_14635	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
F9277_14645	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
F9277_14650	ENOG4105EN6	Membrane
F9277_14655	ENOG4105VP0	transcriptional regulator, lysR family
F9277_14660	ENOG4105EJ9	Membrane
F9277_14675	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
F9277_14680	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
F9277_14685	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
F9277_14690	ENOG4105M6F	mutator MutT protein
F9277_14695	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
F9277_14700	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
F9277_14705	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
F9277_14710	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
F9277_14715	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
F9277_14720	ENOG4105DFU	Cell wall formation (By similarity)
F9277_14725	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
F9277_14735	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
F9277_14740	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
F9277_14745	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
F9277_14750	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
F9277_14755	ENOG4105CJN	penicillin-binding protein
F9277_14760	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
F9277_14765	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
F9277_14780	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
F9277_14790	ENOG41082RQ	UPF0102 protein
F9277_14795	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
F9277_14800	ENOG4105W4M	Transport-associated protein
F9277_14805	ENOG4105KB2	stringent starvation protein b
F9277_14810	ENOG4107MKT	Stringent starvation protein a
F9277_14815	ENOG4105EIX	cytochrome c1
F9277_14820	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F9277_14825	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
F9277_14830	ENOG4108UJD	30S ribosomal protein S9
F9277_14835	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
F9277_14845	ENOG4105D6Z	AFG1 family ATPase
F9277_14855	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
F9277_14865	ENOG4105C0H	protease
F9277_14870	ENOG4105C0H	protease
F9277_14875	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F9277_14880	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F9277_14885	ENOG4105IPS	esterase
F9277_14890	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
F9277_14895	ENOG4108SX3	cytoplasmic protein
F9277_14900	ENOG41087AY	ADP-Ribose pyrophosphatase
F9277_14905	ENOG4105DFG	type I secretion outer membrane protein
F9277_14910	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
F9277_14915	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
F9277_14920	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_14930	ENOG4105I7R	Adenylate cyclase
F9277_14935	ENOG4107IX6	phosphate transport regulator
F9277_14940	ENOG4105CJ3	phosphate transporter
F9277_14945	ENOG4106MWK	domain protein
F9277_14960	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
F9277_14965	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
F9277_14970	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F9277_14975	ENOG4107ZVW	dihydroneopterin aldolase
F9277_14980	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
F9277_14985	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
F9277_14990	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F9277_14995	ENOG4105VCC	30S ribosomal protein S21
F9277_15000	ENOG4105KTH	gatB Yqey
F9277_15005	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
F9277_15010	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F9277_15020	ENOG4107RRE	RNA-directed DNA polymerase
F9277_15080	ENOG4105CTS	PTS system mannitol-specific
F9277_15085	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
F9277_15090	ENOG4105E61	Mannitol repressor protein
F9277_15095	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
F9277_15100	ENOG4105GR3	Histidine kinase
F9277_15120	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
F9277_15125	ENOG410804X	Transcriptional regulator
F9277_15135	ENOG4105CA9	Pyruvate kinase
F9277_15145	ENOG4105BZU	Histidine kinase
F9277_15150	ENOG4108ZP8	Acetolactate synthase small subunit
F9277_15155	ENOG4105C7K	acetolactate synthase
F9277_15160	ENOG4108IQE	Amp-dependent synthetase and ligase
F9277_15165	ENOG41064T2	transcriptional regulator, lysR family
F9277_15190	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
F9277_15195	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
F9277_15200	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F9277_15205	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
F9277_15215	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
F9277_15220	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
F9277_15225	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
F9277_15230	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
F9277_15235	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
F9277_15240	ENOG4105NWN	ApaG protein
F9277_15245	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
F9277_15255	ENOG4107XM3	UPF0442 protein
F9277_15260	ENOG4105DWK	Membrane
F9277_15265	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F9277_15270	ENOG4105K46	50S ribosomal protein l27
F9277_15275	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
F9277_15280	ENOG4105EAH	synthase
F9277_15290	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
F9277_15295	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
F9277_15320	ENOG4107T0D	ABC, transporter
F9277_15325	ENOG4106SMU	thiamine transporter membrane protein
F9277_15330	ENOG4105DP9	ABC transporter
F9277_15335	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
F9277_15340	ENOG4105DFU	Cell wall formation (By similarity)
F9277_15345	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F9277_15350	ENOG4105F0N	pyrophosphate phospho-hydrolase
F9277_15360	ENOG41066HZ	AIG2-like family
F9277_15370	ENOG4105CFU	surface antigen
F9277_15375	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
F9277_15385	ENOG4108UUE	Transcriptional regulator
F9277_15400	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
F9277_15420	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
F9277_15430	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
F9277_15435	ENOG4105C11	sulfate adenylyltransferase), subunit 2
F9277_15440	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
F9277_15445	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
F9277_15455	ENOG4105C1J	atp-dependent rna helicase
F9277_15460	ENOG4107YB6	acetyltransferase, (GNAT) family
F9277_15475	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F9277_15485	ENOG4108ZT0	50S ribosomal protein l17
F9277_15490	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F9277_15495	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
F9277_15500	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
F9277_15505	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F9277_15515	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
F9277_15520	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
F9277_15525	ENOG4105VPB	50S ribosomal protein L30
F9277_15530	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
F9277_15540	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
F9277_15545	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
F9277_15550	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
F9277_15555	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
F9277_15560	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
F9277_15565	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
F9277_15570	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
F9277_15575	ENOG41083MP	50s ribosomal protein l29
F9277_15580	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
F9277_15585	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
F9277_15590	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
F9277_15595	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
F9277_15600	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
F9277_15605	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
F9277_15610	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
F9277_15615	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
F9277_15620	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
F9277_15625	ENOG4105VFB	Binds the 23S rRNA (By similarity)
F9277_15635	ENOG4105C25	Primosomal protein n'
F9277_15640	ENOG4105ETE	Transcriptional regulator (LacI family
F9277_15650	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
F9277_15655	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
F9277_15660	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
F9277_15665	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
F9277_15670	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
F9277_15675	ENOG4105CBT	Fructose-1,6-bisphosphatase
F9277_15705	ENOG4105CP7	Triose-phosphate isomerase
F9277_15710	ENOG4105CY0	Metallo-Beta-Lactamase
F9277_15720	ENOG4105ESV	Glycosyl transferase, family 4
F9277_15725	ENOG4105EIP	mannose-6-phosphate isomerase
F9277_15735	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
F9277_15740	ENOG4108RYC	glycosyltransferase
F9277_15765	ENOG4107T8Q	Glycosyl transferase (Group 1
F9277_15810	ENOG4105E3R	(LipO)protein
F9277_15815	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
F9277_15820	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
F9277_15830	ENOG4105XA0	heptosyltransferase ii
F9277_15835	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
F9277_15850	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
F9277_15855	ENOG4105CHR	reductase
F9277_15865	ENOG4108P1X	synthase
F9277_15885	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
F9277_15890	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
F9277_15895	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
F9277_15900	ENOG41080IJ	Diacylglycerol kinase
F9277_15905	ENOG4105DKP	glycosyl transferase, family 9
F9277_15910	ENOG4106WTF	Glycosyl transferase, family 2
F9277_15920	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
F9277_15925	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
F9277_15930	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
F9277_15940	ENOG4108I6E	Sulfatase
F9277_15950	ENOG4105KDC	50s ribosomal protein l28
F9277_15955	ENOG4105W5Q	DNA repair protein (RadC
F9277_15960	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_15970	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
F9277_15975	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
F9277_15980	ENOG4105D1S	lipid A biosynthesis
F9277_15985	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
F9277_15990	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
F9277_15995	ENOG4105DSJ	YicC domain protein
F9277_16000	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
F9277_16010	ENOG4105DWP	Membrane
F9277_16025	ENOG4108JQ7	(ABC) transporter
F9277_16035	ENOG4107QRA	Extracellular solute-binding protein, family 5
F9277_16040	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
F9277_16045	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
F9277_16075	ENOG4109015	Biopolymer transport protein exbD tolR
F9277_16090	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
F9277_16095	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
F9277_16100	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
F9277_16105	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
F9277_16110	ENOG4105CB5	ATP-dependent DNA helicase recG
F9277_16120	ENOG4105C2W	permease
F9277_16125	ENOG4105E0F	Histidine kinase
F9277_16130	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
F9277_16140	ENOG4108RRZ	Transcription elongation factor GreB
F9277_16150	ENOG4105BZM	domain protein
F9277_16160	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
F9277_16165	ENOG4105MJ2	Competence protein
F9277_16170	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
F9277_16175	ENOG4107RK2	ADP-ribose diphosphatase NudE
F9277_16180	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
F9277_16185	ENOG4105PIC	general secretion pathway protein N
F9277_16190	ENOG4105U1E	general secretion pathway protein M
F9277_16195	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
F9277_16200	ENOG4108RTD	type II secretion system protein K
F9277_16205	ENOG4108WWZ	General secretion pathway protein J
F9277_16210	ENOG4105X5Z	General secretion pathway protein I
F9277_16215	ENOG4105VWV	general secretion pathway protein h
F9277_16220	ENOG4108VAU	general secretion pathway protein G
F9277_16225	ENOG4105D7Q	type ii secretion system
F9277_16230	ENOG4107QHF	type ii secretion system protein e
F9277_16240	ENOG4108XKW	General secretion pathway protein C
F9277_16245	ENOG4105VEJ	Heat shock protein
F9277_16250	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
F9277_16255	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
F9277_16265	ENOG4105SUU	thioesterase domain
F9277_16270	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
F9277_16275	ENOG4107S2Z	UPF0761 membrane protein
F9277_16300	ENOG4105C5F	glutamine synthetase
F9277_16310	ENOG4105CUX	Signal transduction histidine kinase
F9277_16315	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_16320	ENOG4105BZU	Histidine kinase
F9277_16325	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
F9277_16330	ENOG4105D4P	Coproporphyrinogen iii oxidase
F9277_16340	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
F9277_16355	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
F9277_16365	ENOG4105C2M	dna polymerase I
F9277_16380	ENOG4105D52	delta-aminolevulinic acid dehydratase
F9277_16385	ENOG4105F8V	Hydrolase, tatD family
F9277_16390	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
F9277_16395	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
F9277_16400	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
F9277_16405	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
F9277_16410	ENOG4105JC1	sterol-binding domain protein
F9277_16420	ENOG4105CGY	Dna recombination protein
F9277_16430	ENOG4105BZU	Histidine kinase
F9277_16440	ENOG4105CBX	hi0933 family
F9277_16445	ENOG4108V6B	universal stress protein B
F9277_16450	ENOG41090A1	ferritin
F9277_16460	ENOG4108M6U	Universal stress protein A
F9277_16465	ENOG4105EMK	carboxylate amino acid amine transporter
F9277_16480	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
F9277_16485	ENOG4105BZU	Histidine kinase
F9277_16490	ENOG4108VVK	transcriptional Regulator, AsnC
F9277_16495	ENOG4105DGW	oligopeptidase A
F9277_16505	ENOG4105D6S	protein involved in catabolism of external DNA
F9277_16515	ENOG4105DC8	reductase
F9277_16520	ENOG4108UHU	Aldolase
F9277_16525	ENOG4105C6Z	Gluconate
F9277_16530	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
F9277_16535	ENOG4105C01	Dihydroxy-acid dehydratase
F9277_16550	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
F9277_16555	ENOG41064T2	transcriptional regulator, lysR family
F9277_16560	ENOG4105DIQ	Transcriptional regulator
F9277_16595	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
F9277_16600	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
F9277_16605	ENOG4105DEF	Extracellular solute-binding protein, family 5
F9277_16610	ENOG4108JQ6	ABC transporter
F9277_16620	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F9277_16650	ENOG4105MPD	Cytochrome
F9277_16655	ENOG4105C4R	Atp-dependent dna helicase
F9277_16660	ENOG41067SE	Tetr family transcriptional regulator
F9277_16665	ENOG410624X	efflux transporter, rnd family, mfp subunit
F9277_16670	ENOG4105BZS	acriflavin resistance protein
F9277_16680	ENOG4105W0Z	cytoplasmic protein
F9277_16685	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
F9277_16690	ENOG4105EMY	transcriptional regulator
F9277_16740	ENOG4108Z0R	Transferase
F9277_16750	ENOG4105E2X	shikimate dehydrogenase
F9277_16755	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
F9277_16760	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
F9277_16765	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
F9277_16770	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
F9277_16775	ENOG4108WI1	Dna topoisomerase
F9277_16780	ENOG4108RPN	Protein smg homolog
F9277_16785	ENOG4105C79	DNA protecting protein DprA
F9277_16800	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
F9277_16805	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
F9277_16810	ENOG4105C1A	potassium transporter peripheral membrane
F9277_16815	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
F9277_16825	ENOG4108UT2	hemolysin iii
F9277_16830	ENOG4108N23	SpoOM-related protein
F9277_16840	ENOG4105PC1	Conserved Protein
F9277_16850	ENOG4105E27	serine threonine protein kinase
F9277_16855	ENOG4108Z33	Thiol disulfide Interchange Protein
F9277_16860	ENOG4106HNH	Acyl-transferase
F9277_16870	ENOG4105BZU	Histidine kinase
F9277_16875	ENOG4105C0P	Mg chelatase subunit ChlI
F9277_16885	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
F9277_16890	ENOG4105CM2	brancheD-chain amino acid aminotransferase
F9277_16895	ENOG4105C01	Dihydroxy-acid dehydratase
F9277_16900	ENOG4105C7B	Threonine dehydratase
F9277_16905	ENOG4105F52	Transcriptional regulator
F9277_16910	ENOG4105CZQ	inner membrane transport protein YdhC
F9277_16915	ENOG4105F87	Dehydratase
F9277_16920	ENOG4105EAD	ABC transporter
F9277_16925	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
F9277_16930	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
F9277_16935	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
F9277_16940	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
F9277_16945	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
F9277_16950	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F9277_16955	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F9277_16960	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F9277_16965	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
F9277_16970	ENOG410684E	atp synthase
F9277_16975	ENOG4105FA0	parb-like partition protein
F9277_16980	ENOG4107QJE	Chromosome Partitioning Protein
F9277_16985	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
F9277_16990	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
F9277_16995	ENOG4105QTB	Flavodoxin
F9277_17000	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
F9277_17005	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
F9277_17010	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
F9277_17015	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
F9277_17030	ENOG4105E5Q	amino acid AbC transporter
F9277_17035	ENOG4105EAB	amino acid AbC transporter
F9277_17045	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
F9277_17050	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
F9277_17055	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
F9277_17060	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
F9277_17065	ENOG4108ZNX	Heat shock protein
F9277_17070	ENOG4105JKW	Valine--pyruvate aminotransferase
F9277_17075	ENOG4107T9C	Alpha amylase catalytic region
F9277_17080	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
F9277_17085	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
F9277_17100	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
F9277_17115	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
F9277_17120	ENOG4105CHU	acetyl-coa acetyltransferase
F9277_17125	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
F9277_17130	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
F9277_17135	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
F9277_17140	ENOG4108RR8	protoporphyrinogen oxidase
F9277_17190	ENOG4105E3B	Multicopper oxidase
F9277_17195	ENOG4105WMR	Protein CrcB homolog
F9277_17200	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
F9277_17210	ENOG4105D06	uba thif-type nad fad binding protein
F9277_17215	ENOG4105WHD	thiamine biosynthesis protein ThiS
F9277_17220	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
F9277_17225	ENOG4105D41	biosynthesis protein thiH
F9277_17230	ENOG4105DC7	peptidase M24
F9277_17230	ENOG4105DC7	peptidase M24
F9277_17235	ENOG4105G2Y	Transcriptional regulator
F9277_17240	ENOG4105CNH	Multidrug resistance protein MdtL
F9277_17260	ENOG4105E18	UPF0276 protein
F9277_17270	ENOG4105C4R	Atp-dependent dna helicase
F9277_17280	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
F9277_17295	ENOG4105FR1	rard protein
F9277_17300	ENOG4105C9U	ATP-dependent DNA helicase RecQ
F9277_17315	ENOG4105EX9	Membrane
F9277_17320	ENOG4105C9X	ppx gppa phosphatase
F9277_17325	ENOG4105C1J	atp-dependent rna helicase
F9277_17330	ENOG4105K63	Thioredoxin
F9277_17335	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
F9277_17345	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
F9277_17350	ENOG4108ZIT	Ferredoxin, 2FE-2S
F9277_17355	ENOG4107QK7	reductase
F9277_17395	ENOG410601J	HemY protein
F9277_17400	ENOG4105ECF	c-methyltransferase
F9277_17405	ENOG41076E6	Uroporphyrinogen-III Synthase
F9277_17410	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
F9277_17415	ENOG4107T0K	Adenylate cyclase
F9277_17420	ENOG4105XQ6	frataxin-like protein
F9277_17430	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
F9277_17435	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
F9277_17445	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
F9277_17450	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
F9277_17455	ENOG4105BZU	Histidine kinase
F9277_17460	ENOG4106IUH	DTW domain containing protein
F9277_17475	ENOG4105DQF	Hydrolase
F9277_17480	ENOG4108EUD	Lysophospholipase
F9277_17485	ENOG410829K	Lysine exporter protein (Lyse ygga)
F9277_17490	ENOG4105D58	Diguanylate phosphodiesterase
F9277_17495	ENOG41082YX	Transcriptional regulator, arsr family
F9277_17500	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
F9277_17550	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
F9277_17560	ENOG4106H78	methyltransferase
F9277_17565	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
F9277_17570	ENOG4105CAK	Cell division ATP-binding protein ftsE
F9277_17575	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
F9277_17580	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F9277_17585	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
F9277_17590	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
F9277_17595	ENOG4105X6C	Flagellar basal body-associated protein FliL
F9277_17600	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
F9277_17605	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
F9277_17610	ENOG4105E55	glycerol-3-phosphate acyltransferase
F9277_17620	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
F9277_17630	ENOG4107R73	Mate efflux family protein
F9277_17635	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
F9277_17670	ENOG4105CVR	type I restriction-modification system
F9277_17675	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
F9277_17695	ENOG4108YGG	dna repair protein
F9277_17750	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
F9277_17755	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F9277_17765	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
F9277_17845	ENOG4105JIM	Phosphatidylserine synthase
F9277_17855	ENOG4105D4A	Cell wall formation (By similarity)
F9277_17860	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
F9277_17865	ENOG4105CS9	pantothenic acid kinase
F9277_17895	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
F9277_17905	ENOG4105PM1	preprotein translocase subunit SecE
F9277_17910	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
F9277_17915	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
F9277_17920	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
F9277_17925	ENOG4108VZM	50s ribosomal protein L10
F9277_17930	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
F9277_17935	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F9277_17940	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
F9277_17945	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
F9277_17950	ENOG4105E09	nadh pyrophosphatase
F9277_17965	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
F9277_17970	ENOG4108RG0	uracil-dna glycosylase
F9277_17975	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
F9277_17980	ENOG4105R2J	Conserved Protein
F9277_18000	ENOG4105C12	Phosphoribosylglycinamide synthetase
F9277_18005	ENOG4105DC1	bifunctional purine biosynthesis protein purh
F9277_18010	ENOG4105W1Y	Transcriptional regulator
F9277_18015	ENOG4108M3R	transcriptional activator CadC
F9277_18025	ENOG4105D5Q	Arginine ornithine antiporter
F9277_18030	ENOG4105CXN	decarboxylase
F9277_18075	ENOG4105W1N	transcriptional regulator
F9277_18080	ENOG4105HEI	LysR family (Transcriptional regulator
F9277_18095	ENOG4105C5H	ABC transporter
F9277_18100	ENOG4105CHF	Glutathione S-transferase
F9277_18105	ENOG4105Q8W	reductase
F9277_18110	ENOG4105HEI	LysR family (Transcriptional regulator
F9277_18115	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
F9277_18120	ENOG4105C5H	ABC transporter
F9277_18135	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
F9277_18140	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
F9277_18155	ENOG4105E18	UPF0276 protein
F9277_18170	ENOG4105C4M	(Ubiquinol oxidase) subunit I
F9277_18175	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
F9277_18210	ENOG4107U2T	alpha beta
F9277_18215	ENOG4105E7U	AraC family transcriptional regulator
F9277_18220	ENOG41075H3	AraC family transcriptional regulator
F9277_18230	ENOG4105C6N	Formate acetyltransferase
F9277_18235	ENOG4105F1A	Pyruvate formate-lyase
F9277_18240	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
F9277_18255	ENOG4105EB3	Histidine kinase
F9277_18260	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
F9277_18270	ENOG4105I4A	GCN5-related N-acetyltransferase
F9277_18280	ENOG4105CNH	Multidrug resistance protein MdtL
F9277_18285	ENOG4105G2Y	Transcriptional regulator
F9277_18295	ENOG4105EJC	lysr family transcriptional regulator
F9277_18300	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
F9277_18340	ENOG4105IPI	Membrane
F9277_18345	ENOG41068P6	UPF0319 protein
F9277_18360	ENOG4105DP0	ferredoxin-NADP reductase
F9277_18370	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
F9277_18375	ENOG4105EJC	lysr family transcriptional regulator
F9277_18385	ENOG4108RCM	Nitroreductase
F9277_18400	ENOG4105DZ1	carboxypeptidase
F9277_18415	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
F9277_18435	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F9277_18440	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
F9277_18445	ENOG4105C72	UPF0176 protein
F9277_18455	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
F9277_18470	ENOG4108NRW	Phospholipase, patatin family
F9277_18475	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
F9277_18485	ENOG4105DAY	polysaccharide export protein
F9277_18495	ENOG4105D75	Capsular exopolysaccharide family
F9277_18505	ENOG4105N0V	mono-oxygenase ydhR
F9277_18510	ENOG4105C5Q	Transcriptional regulator
F9277_18540	ENOG4105CK2	sodium dicarboxylate symporter
F9277_18560	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
F9277_18565	ENOG4108P2H	Inner membrane protein YjiG
F9277_18570	ENOG41074DU	domain protein
F9277_18585	ENOG4107T9C	Alpha amylase catalytic region
F9277_18590	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
F9277_18595	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
F9277_18600	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
F9277_18610	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
F9277_18620	ENOG41061ZR	Transcriptional regulator
F9277_18645	ENOG4105CI1	PTS System
F9277_18650	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
F9277_18655	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
F9277_18685	ENOG4105EDK	PfkB domain protein
F9277_18690	ENOG4105CIB	oxidoreductase Domain protein
F9277_18695	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
F9277_18705	ENOG4107QNK	)-transporter
F9277_18710	ENOG4105HEI	LysR family (Transcriptional regulator
F9277_18720	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
F9277_18725	ENOG4105CHU	acetyl-coa acetyltransferase
F9277_18745	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
F9277_18755	ENOG4105D5Q	Arginine ornithine antiporter
F9277_18760	ENOG4105CXN	decarboxylase
F9277_18780	ENOG4105BZW	Glycerate kinase
F9277_18785	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
F9277_18795	ENOG4105CI2	imidazolone-5-propionate hydrolase
F9277_18840	ENOG4105G2Y	Transcriptional regulator
F9277_18855	ENOG4105BZ1	(ABC) transporter
F9277_18860	ENOG4105BZ1	(ABC) transporter
F9277_18865	ENOG4107ZSV	Receptor
F9277_18890	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
F9277_18905	ENOG4107WCA	isomerase
F9277_18925	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
F9277_18945	ENOG4105EIF	outer membrane protein W
F9277_18950	ENOG4107W31	Pentapeptide repeat protein
F9277_18975	ENOG410814C	multidrug resistance protein
F9277_18985	ENOG4108M1A	Chitin-binding protein
F9277_18990	ENOG4105EW9	transcriptional regulator AsnC family
F9277_19005	ENOG4105Q26	Siderophore-interacting protein
F9277_19010	ENOG4105CC0	LysR family Transcriptional regulator
F9277_19040	ENOG4105KAF	membrAne
F9277_19050	ENOG4108KHX	Diguanylate cyclase
F9277_19060	ENOG4108HCJ	Hydrolase
F9277_19070	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
F9277_19075	ENOG4105D3G	Pseudouridine synthase
F9277_19080	ENOG4105UQX	Mate efflux family protein
F9277_19085	ENOG4105ETE	Transcriptional regulator (LacI family
F9277_19090	ENOG4108IJ9	(ABC) transporter
F9277_19100	ENOG4105DRS	transport system, permease
F9277_19115	ENOG41060NJ	transcriptional regulator
F9277_19120	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
F9277_19125	ENOG4108K0B	C-di-gmp phosphodiesterase
F9277_19135	ENOG4105NBK	UPF0345 protein
F9277_19165	ENOG4105DN9	Na H antiporter
F9277_19200	ENOG4105CFP	Peptidase U32
F9277_19210	ENOG4105D2N	Aldolase
F9277_19215	ENOG4105CE4	GlcNAc 6-P deacetylase
F9277_19220	ENOG4108YTN	IIa component
F9277_19225	ENOG4105F3R	pts system mannose fructose sorbose family iid
F9277_19230	ENOG4105ETZ	PTS System
F9277_19235	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
F9277_19240	ENOG4105E70	isomerase
F9277_19245	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
F9277_19250	ENOG4105E98	transcriptional regulator DeoR family
F9277_19255	ENOG4105E98	transcriptional regulator DeoR family
F9277_19265	ENOG4105C19	ABC transporter
F9277_19300	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
F9277_19305	ENOG4105D03	DNA-3-methyladenine glycosylase II
F9277_19315	ENOG4108VGI	doxx family
F9277_19335	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
F9277_19355	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
F9277_19365	ENOG4108K4B	hydrolase
F9277_19415	ENOG4105NXH	GreA GreB family elongation factor
F9277_19420	ENOG4105KME	endoribonuclease L-psp
F9277_19440	ENOG4105EHG	Permease protein
F9277_19450	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
F9277_19455	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
F9277_19465	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
F9277_19470	ENOG4105IY8	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
F9277_19475	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
F9277_19480	ENOG4105CQM	Urea amidohydrolase subunit alpha
F9277_19485	ENOG4105KI2	Urea amidohydrolase subunit beta
F9277_19490	ENOG4108YZ9	Urea amidohydrolase subunit gamma
F9277_19495	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
F9277_19510	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
F9277_19535	ENOG4105D6U	Sodium Glutamate Symporter
F9277_19540	ENOG4107U9B	transcriptional regulator
F9277_19545	ENOG4105CZV	ABC transporter
F9277_19560	ENOG4105D6U	Sodium Glutamate Symporter
F9277_19580	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_19585	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
F9277_19595	ENOG4108VAC	response regulator
F9277_19600	ENOG4108HRK	Histidine kinase
F9277_19620	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F9277_19630	ENOG4105CR8	Transcriptional regulator
F9277_19635	ENOG4105Y49	secretion protein, HlyD family
F9277_19650	ENOG4105CNI	cell division protein FtsW
F9277_19655	ENOG4105CDY	transcriptional regulatory protein
F9277_19665	ENOG4105BZU	Histidine kinase
F9277_19690	ENOG4108JQ7	(ABC) transporter
F9277_19710	ENOG4106RMF	ParB family
F9277_19715	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
F9277_19720	ENOG41067XB	TonB family
F9277_19725	ENOG4108ZZF	transport protein (ExbD)
F9277_19730	ENOG4105CWK	Biopolymer transport protein, ExbB
F9277_19765	ENOG4108SF5	RNA Polymerase
F9277_19780	ENOG4105EQ2	LysR family Transcriptional regulator
F9277_19795	ENOG4108J59	Extracellular solute-binding protein, family 5
F9277_19810	ENOG4108JJA	ABC, transporter
F9277_19825	ENOG4107QZV	Type I secretion membrane fusion protein
F9277_19830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_19835	ENOG4105CQZ	Histidine kinase
F9277_19840	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
F9277_19855	ENOG4105C26	Dehydrogenase
F9277_19865	ENOG4105CK7	Sodium proline symporter
F9277_19910	ENOG4105EW9	transcriptional regulator AsnC family
F9277_19920	ENOG4105BZ1	(ABC) transporter
F9277_19935	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F9277_19945	ENOG4105C4X	radical SAM domain protein
F9277_19950	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
F9277_19955	ENOG4105EP8	Glycosyl Hydrolase Family 88
F9277_19965	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
F9277_19970	ENOG4105CHR	reductase
F9277_19975	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
F9277_19980	ENOG4108UHU	Aldolase
F9277_19995	ENOG4107QZ2	Sulfatase
F9277_20000	ENOG4105VG5	Membrane
F9277_20030	ENOG410839U	amino acid
F9277_20040	ENOG4105EJ2	Transcriptional regulator
F9277_20045	ENOG4105P66	Membrane
F9277_20050	ENOG4108UHU	Aldolase
F9277_20055	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
F9277_20065	ENOG4105DEI	Mannitol dehydrogenase
F9277_20070	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
F9277_20075	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
F9277_20080	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
F9277_20085	ENOG4105C6F	GntR Family Transcriptional Regulator
F9277_20090	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
F9277_20095	ENOG4105VMP	Transcriptional regulator
F9277_20110	ENOG4105C87	Aminotransferase class I and II
F9277_20115	ENOG410904A	RNA polymerase
F9277_20125	ENOG4105C1J	atp-dependent rna helicase
F9277_20130	ENOG4105RW8	MltA-interacting MipA family protein
F9277_20140	ENOG4107YB6	acetyltransferase, (GNAT) family
F9277_20145	ENOG4108RPX	mosc domain containing protein
F9277_20160	ENOG4108XM1	transcriptional regulator AsnC family
F9277_20175	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_20180	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
F9277_20215	ENOG4107FKK	extracellular solute-binding protein family 1
F9277_20225	ENOG4105CG3	alpha amylase, catalytic region
F9277_20230	ENOG4105C5Q	Transcriptional regulator
F9277_20265	ENOG4108JU3	Alkyl hydroperoxide reductase
F9277_20270	ENOG4105D3R	alkyl hydroperoxide reductase
F9277_20280	ENOG4105K56	Transcriptional regulator
F9277_20285	ENOG4108ZHJ	Organic hydroperoxide resistance protein
F9277_20300	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_20305	ENOG4107RAN	Peptidase, M16
F9277_20330	ENOG4105DR5	peptidase
F9277_20350	ENOG41062JF	Transcriptional regulator
F9277_20355	ENOG4108IPW	abc transporter atp-binding protein
F9277_20360	ENOG4105CM4	permease protein
F9277_20365	ENOG4105DHS	permease protein
F9277_20385	ENOG4105D05	Receptor
F9277_20405	ENOG4105E5M	Multidrug resistance protein D
F9277_20420	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
F9277_20430	ENOG4105D5B	Sulfite reductase, subunit A
F9277_20440	ENOG4105BZU	Histidine kinase
F9277_20450	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
F9277_20470	ENOG4108K8S	endonuclease I
F9277_20475	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F9277_20520	ENOG4108W0I	acetyltransferase
F9277_20540	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
F9277_20550	ENOG4105CUW	cytochrome C-TYPE protein
F9277_20555	ENOG4107QY8	reductase
F9277_20560	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
F9277_20565	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
F9277_20570	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
F9277_20575	ENOG4105ETU	transcriptional activator (TenA
F9277_20580	ENOG4107Z6I	Thiamine biosynthesis protein
F9277_20585	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
F9277_20590	ENOG4108YI8	ABC transporter
F9277_20595	ENOG4105DWF	phosphomethylpyrimidine kinase
F9277_20610	ENOG4108TEM	pseudouridine methyltransferase
F9277_20665	ENOG4108YYI	Protein of unknown function (DUF2810)
F9277_20670	ENOG4105C5I	Dehydrogenase
F9277_20680	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
F9277_20685	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
F9277_20690	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
F9277_20695	ENOG410804D	Sensor Signal Transduction Histidine Kinase
F9277_20720	ENOG4109015	Biopolymer transport protein exbD tolR
F9277_20765	ENOG4105DSE	periplasmic solute binding protein
F9277_20770	ENOG4105DIK	(ABC) transporter
F9277_20775	ENOG4105CC5	ABC transporter
F9277_20790	ENOG4105CUG	Oligopeptidase b
F9277_20795	ENOG4105E5M	Multidrug resistance protein D
F9277_20800	ENOG4105CYW	agmatinase
F9277_20805	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
F9277_20815	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F9277_20820	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F9277_20845	ENOG4108WAV	Transcriptional regulator
F9277_20875	ENOG4105CQZ	Histidine kinase
F9277_20880	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_20885	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
F9277_20910	ENOG4105D5U	fad dependent oxidoreductase
F9277_20920	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F9277_20925	ENOG4105C0F	tryptophanase EC 4.1.99.1
F9277_20945	ENOG4105D9N	nucleoside
F9277_20970	ENOG4105BZU	Histidine kinase
F9277_20985	ENOG4106TD9	Diguanylate cyclase
F9277_20990	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
F9277_20995	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
F9277_21010	ENOG4105E0X	reductase
F9277_21015	ENOG4108UKZ	OsmC family
F9277_21060	ENOG4105JQN	Transcriptional regulator
F9277_21065	ENOG4105PAD	Hydrolase
F9277_21100	ENOG4105KUU	lipolytic protein G-D-S-L family
F9277_21105	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
F9277_21130	ENOG4105ETE	Transcriptional regulator (LacI family
F9277_21135	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
F9277_21140	ENOG4108JPW	Aminotransferase
F9277_21145	ENOG4107STF	Involved in phosphonate degradation (By similarity)
F9277_21160	ENOG4107RCV	ABC transporter, permease
F9277_21180	ENOG4108MJ5	VirK protein
F9277_21190	ENOG4105CJP	fad dependent oxidoreductase
F9277_21205	ENOG4105ETT	transcriptional Regulator, LysR family
F9277_21225	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
F9277_21230	ENOG4105DUX	Transporter
F9277_21235	ENOG4105EJQ	L-serine dehydratase
F9277_21260	ENOG4105E9H	Lytic Murein transglycosylase
F9277_21280	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
F9277_21285	ENOG4108ZC9	flagellar basal-body rod protein flgc
F9277_21290	ENOG4105W00	Flagellar hook capping protein
F9277_21295	ENOG4105BZE	flagellar hook protein, FlgE
F9277_21300	ENOG4108KPB	Flagellar basal-body rod protein FlgF
F9277_21305	ENOG4105CGA	flagellar basal-body rod protein FlgG
F9277_21310	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
F9277_21315	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
F9277_21320	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
F9277_21325	ENOG4105E1Q	flagellar hook-associated protein
F9277_21330	ENOG4105DTJ	flagellar hook-associated protein
F9277_21350	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
F9277_21365	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
F9277_21385	ENOG4107SJW	iron permease, FTR1
F9277_21400	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
F9277_21410	ENOG4107XPZ	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
F9277_21425	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
F9277_21440	ENOG4105F87	Dehydratase
F9277_21450	ENOG4105KWG	Pfam:DUF1696
F9277_21475	ENOG4105ER2	Ompa motb domain protein
F9277_21480	ENOG4107RD7	Flagellar Motor Protein, MotA
F9277_21505	ENOG4105MQ3	flagellar protein FliS
F9277_21510	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
F9277_21520	ENOG4105I03	Flagellin
F9277_21535	ENOG4105D00	flagellar biosynthetic protein flhB
F9277_21540	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
F9277_21545	ENOG4105VS8	Flagellar biosynthetic protein fliq
F9277_21550	ENOG4105CN7	Flagellar biosynthetic protein FliP
F9277_21555	ENOG4105DD5	Flagellar motor switch protein
F9277_21570	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
F9277_21580	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
F9277_21585	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
F9277_21595	ENOG4108JIR	Flagellum-specific ATP synthase
F9277_21605	ENOG4105BZU	Histidine kinase
F9277_21630	ENOG4107SSZ	Phosphatase
F9277_21650	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
F9277_21655	ENOG4105EXG	Transcriptional regulator
F9277_21675	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
F9277_21690	ENOG4106PMH	Extracellular solute-binding protein family 3
F9277_21695	ENOG4105BZU	Histidine kinase
F9277_21700	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
F9277_21705	ENOG4105CPQ	Dehydrogenase
F9277_21720	ENOG4108KB2	LysR family Transcriptional regulator
F9277_21755	ENOG41090VV	Protein of unknown function (DUF2846)
F9277_21760	ENOG4108UHE	carbonic anhydrase
F9277_21765	ENOG4108Z4X	TRANSCRIPTIONal
F9277_21790	ENOG4107RZC	phospholipase d
F9277_21800	ENOG4105BZS	acriflavin resistance protein
F9277_21810	ENOG4105BZS	acriflavin resistance protein
F9277_21850	ENOG4105CEY	Amp-dependent synthetase and ligase
F9277_21865	ENOG41086KC	Transcriptional regulator
F9277_21875	ENOG4105BZU	Histidine kinase
F9277_21890	ENOG4105D6U	Sodium Glutamate Symporter
F9277_21895	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
F9277_21900	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
F9277_21910	ENOG4107V40	secretion protein, HlyD family
F9277_21915	ENOG4105HEI	LysR family (Transcriptional regulator
F9277_21930	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
F9277_21935	ENOG4108S01	response regulator
F9277_21945	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
F9277_21950	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
F9277_21955	ENOG4105HDK	L-asparaginase
F9277_21965	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
F9277_21990	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
F9277_22005	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F9277_22015	ENOG4105F27	Major Facilitator
F9277_22020	ENOG4105CHR	reductase
F9277_22045	ENOG4105HEI	LysR family (Transcriptional regulator
F9277_22055	ENOG4105C1J	atp-dependent rna helicase
F9277_22075	ENOG4105JGI	Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes (By similarity)
F9277_22095	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F9277_22100	ENOG410874W	AraC family transcriptional regulator
F9277_22105	ENOG4105EJC	lysr family transcriptional regulator
F9277_22115	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
F9277_22145	ENOG4105FP6	Protein of unknown function (DUF3302)
F9277_22150	ENOG4105EFX	secretion protein, HlyD family
F9277_22155	ENOG4105G2Y	Transcriptional regulator
F9277_22165	ENOG4105EIP	mannose-6-phosphate isomerase
F9277_22170	ENOG4105DM4	PTS System
F9277_22175	ENOG4106R3P	AraC family transcriptional regulator
F9277_22185	ENOG4108YRF	PTS System
F9277_22190	ENOG4105DM4	PTS System
F9277_22205	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
F9277_22210	ENOG4105CH6	catalase
F9277_22220	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
F9277_22225	ENOG4108WUH	Transcriptional regulator, TetR family
F9277_22230	ENOG4105V0I	UPF0267 protein
F9277_22260	ENOG4107TYR	Glycosyl Transferase
F9277_22270	ENOG4108F2G	Chain length determinant protein
F9277_22285	ENOG4105D3Q	Sugar transferase
F9277_22290	ENOG4108IJ9	(ABC) transporter
F9277_22300	ENOG4107FKK	extracellular solute-binding protein family 1
F9277_22305	ENOG4105D56	permease protein
F9277_22310	ENOG4105EG2	ABC transporter, permease
F9277_22355	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
F9277_22380	ENOG4105CKW	Inner membrane protein yedI
F9277_22385	ENOG4105EKE	dihydroorotase
F9277_22400	ENOG4105QVC	MOSC domain-containing protein
F9277_22400	ENOG4105QVC	MOSC domain-containing protein
F9277_22405	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
F9277_22410	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
F9277_22480	ENOG4108W2Y	isochorismatase
F9277_22485	ENOG4105ECQ	AraC Family Transcriptional Regulator
F9277_22490	ENOG4105EP9	oxidoreductase
F9277_22495	ENOG4105DIJ	Phosphoethanolamine transferase
F9277_22500	ENOG41080IJ	Diacylglycerol kinase
F9277_22510	ENOG4105JJR	Histidine kinase
F9277_22515	ENOG4107EXC	regulatoR
F9277_22520	ENOG4105C94	Transporter
F9277_22525	ENOG4105DIA	mandelate racemase muconate lactonizing
F9277_22530	ENOG4107EFR	Flavocytochrome c
F9277_22545	ENOG4105EMU	Dehydrogenase
F9277_22560	ENOG4108Z33	Thiol disulfide Interchange Protein
F9277_22580	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
F9277_22590	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
F9277_22605	ENOG4105EST	Metal Dependent Phosphohydrolase
F9277_22620	ENOG4105DZC	cytosine deaminase
F9277_22625	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
F9277_22630	ENOG4105CJW	magnesium transporter
F9277_22635	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
F9277_22640	ENOG4105EFX	secretion protein, HlyD family
F9277_22665	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F9277_22670	ENOG4105E0F	Histidine kinase
F9277_22680	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
F9277_22685	ENOG4105DVH	amino acid
F9277_22690	ENOG4108XM1	transcriptional regulator AsnC family
F9277_22720	ENOG4105BZU	Histidine kinase
F9277_22725	ENOG4105EE0	oxidoreductase
F9277_22735	ENOG41090HJ	UPF0265 protein
F9277_22745	ENOG4108YXG	UPF0502 protein
F9277_22750	ENOG41082IR	Excinuclease ABC C subunit domain protein
F9277_22755	ENOG4108QGH	periplasmic
F9277_22760	ENOG4105BZU	Histidine kinase
F9277_22775	ENOG4105EW9	transcriptional regulator AsnC family
F9277_22805	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F9277_22810	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
F9277_22830	ENOG4105CHU	acetyl-coa acetyltransferase
F9277_22840	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
F9277_22855	ENOG4105CUW	cytochrome C-TYPE protein
F9277_22865	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
F9277_22880	ENOG4105BZU	Histidine kinase
F9277_22885	ENOG4105WH1	Two component transcriptional regulator luxr family
F9277_22900	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
F9277_22905	ENOG4107YWA	deoxycytidylate deaminase
F9277_22920	ENOG4108N3W	hemolysin secretion protein
F9277_22925	ENOG4108YZN	class I peptide chain release factor
F9277_22930	ENOG4107VXZ	Hydrolase
F9277_22960	ENOG4108V1T	peptidylprolyl cis-trans isomerase
F9277_22970	ENOG4108ZG0	Ompa motb domain protein
F9277_22990	ENOG4105VEQ	Cold shock protein
F9277_23005	ENOG4105BZU	Histidine kinase
F9277_23025	ENOG4107R39	(ABC) transporter
F9277_23035	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
F9277_23055	ENOG4105DFG	type I secretion outer membrane protein
F9277_23060	ENOG4108MGY	Histidine kinase
F9277_23085	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_23090	ENOG4108RMU	ferritin dps family protein
F9277_23100	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
F9277_23110	ENOG4105C0A	alcohol dehydrogenase
F9277_23120	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
F9277_23140	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
F9277_23145	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
F9277_23155	ENOG4105MIR	Phenylalanine 4-monooxygenase
F9277_23160	ENOG41090A4	Pterin carbinolamine dehydratase
F9277_23190	ENOG4105VRT	cytoplasmic protein
F9277_23225	ENOG4105EM2	membrane
F9277_23230	ENOG41088T4	Helicase IV
F9277_23235	ENOG4108Z5K	methylglyoxal synthase
F9277_23240	ENOG4108SV3	Tmao reductase system periplasmic protein tort
F9277_23245	ENOG4105BZU	Histidine kinase
F9277_23265	ENOG410804D	Sensor Signal Transduction Histidine Kinase
F9277_23275	ENOG4105ENH	Sulfatase
F9277_23280	ENOG4105ENH	Sulfatase
F9277_23290	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F9277_23325	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
F9277_23330	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F9277_23335	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
F9277_23340	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
F9277_23345	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
F9277_23350	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
F9277_23355	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
F9277_23360	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
F9277_23365	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
F9277_23370	ENOG41064T2	transcriptional regulator, lysR family
F9277_23375	ENOG4107TE5	Lipid kinase
F9277_23380	ENOG4108YDI	single-species biofilm formation on inanimate substrate
F9277_23400	ENOG4105C4X	radical SAM domain protein
F9277_23410	ENOG4105F2V	VRR-NUC domain-containing protein
F9277_23425	ENOG4105D0M	Protease HtpX homolog
F9277_23430	ENOG4108V0P	LemA family
F9277_23435	ENOG4105CEE	C4-dicarboxylate transporter
F9277_23455	ENOG4108MGY	Histidine kinase
F9277_23460	ENOG4107KBT	8-Amino-7-oxononanoate synthase
F9277_23465	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
F9277_23470	ENOG4105DR5	peptidase
F9277_23490	ENOG4105KCK	Peptidoglycan-associated lipoprotein
F9277_23495	ENOG4108JUA	Transcriptional regulator
F9277_23500	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F9277_23505	ENOG4108WC9	type VI secretion system effector, hcp1 family
F9277_23510	ENOG4105CS6	Rhs element vgr protein
F9277_23535	ENOG4105D9P	serine threonine protein kinase
F9277_23570	ENOG4105EW9	transcriptional regulator AsnC family
F9277_23630	ENOG4107HQ7	repeat protein
F9277_23635	ENOG4107QNK	)-transporter
F9277_23640	ENOG4108NZE	NAGC-like transcriptional regulator
F9277_23645	ENOG4108ZKT	aldose 1-epimerase
F9277_23650	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
F9277_23655	ENOG4105DBM	Siderophore biosynthesis protein
F9277_23675	ENOG4105E0K	tonB-dependent siderophore receptor
F9277_23680	ENOG4105GAV	receptor
F9277_23685	ENOG4108HUF	Transporter
F9277_23690	ENOG4105DQ5	transport system permease protein
F9277_23695	ENOG4108U1V	ABC transporter, permease
F9277_23700	ENOG4105E0A	ABC, transporter
F9277_23705	ENOG4105D05	Receptor
F9277_23715	ENOG4105BZU	Histidine kinase
F9277_23720	ENOG4105BZU	Histidine kinase
F9277_23725	ENOG4105BZU	Histidine kinase
F9277_23730	ENOG4108WQH	regulatoR
F9277_23735	ENOG4105BZU	Histidine kinase
F9277_23745	ENOG4108WQH	regulatoR
F9277_23750	ENOG4108NVR	Methyl-accepting chemotaxis
F9277_23755	ENOG4108TVJ	Nitroreductase
F9277_23765	ENOG4107R88	Chemotaxis protein (CheV)
F9277_23770	ENOG4108VAU	general secretion pathway protein G
F9277_23780	ENOG4105FR1	rard protein
F9277_23805	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
F9277_23840	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
F9277_23845	ENOG4105E39	Enoyl-CoA hydratase
F9277_23850	ENOG4107QX3	carboxylase
F9277_23855	ENOG4105C1G	acyl-Coa dehydrogenase
F9277_23870	ENOG4105CHU	acetyl-coa acetyltransferase
F9277_23875	ENOG4105C26	Dehydrogenase
F9277_23885	ENOG4105E39	Enoyl-CoA hydratase
F9277_23890	ENOG4105E39	Enoyl-CoA hydratase
F9277_23895	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
F9277_23900	ENOG4105CHR	reductase
F9277_23910	ENOG4105E2S	oxidase) subunit II
F9277_23915	ENOG4105BZ9	Cytochrome C oxidase, subunit I
F9277_23920	ENOG4105CCU	oxidase (Subunit III)
F9277_23925	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
F9277_23930	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
F9277_23940	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F9277_23945	ENOG4106CKV	Pap2 superfamily protein
F9277_23970	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
F9277_23990	ENOG4107RGH	Aldehyde dehydrogenase
F9277_23995	ENOG4105BZ1	(ABC) transporter
F9277_24010	ENOG4105KVH	Transcriptional regulator
F9277_24020	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
F9277_24185	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
F9277_24190	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F9277_24195	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
F9277_24200	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
F9277_24210	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
F9277_24220	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
F9277_24255	ENOG4105DM4	PTS System
F9277_24260	ENOG4105DE4	1-phosphofructokinase
F9277_24265	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
F9277_24270	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
F9277_24285	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
F9277_24290	ENOG4105E5Q	amino acid AbC transporter
F9277_24295	ENOG4106TNF	Periplasmic binding protein
F9277_24300	ENOG4105E5Q	amino acid AbC transporter
F9277_24305	ENOG4105CDA	abc transporter atp-binding protein
F9277_24315	ENOG4108I6A	alcohol dehydrogenase
F9277_24320	ENOG4105CF7	AraC family transcriptional regulator
F9277_24330	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
F9277_24335	ENOG4105CKU	formyltetrahydrofolate synthetase
F9277_24340	ENOG4107RE1	Inosine-guanosine kinase
F9277_24355	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
F9277_24360	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
F9277_24370	ENOG4108NVR	Methyl-accepting chemotaxis
F9277_24385	ENOG4105C1J	atp-dependent rna helicase
F9277_24390	ENOG4108M8H	domain protein
F9277_24405	ENOG4105DS1	cytochrome b561
F9277_24410	ENOG4108YYC	ycei family
F9277_24415	ENOG4105TMB	Formate nitrite transporter
F9277_24425	ENOG4105DUM	transcriptional regulator, lysR family
F9277_24430	ENOG4108UQ5	membrane protein YcdZ
F9277_24435	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
F9277_24440	ENOG4105CGH	5'-nucleotidase
F9277_24445	ENOG4105DU1	integral membrane protein, terc
F9277_24460	ENOG4105C3R	Methionine synthase
F9277_24475	ENOG4108M0H	Extracellular lipase
F9277_24480	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
F9277_24495	ENOG4105KA0	thioesterase Superfamily protein
F9277_24530	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
F9277_24540	ENOG4105BZU	Histidine kinase
F9277_24545	ENOG4105RKW	reductase (By
F9277_24555	ENOG4108I0Y	(ABC) transporter
F9277_24560	ENOG4105CV6	ABC transporter, permease
F9277_24570	ENOG4107R7A	Allophanate hydrolase subunit 2
F9277_24575	ENOG4105P4J	Allophanate hydrolase, subunit 1
F9277_24580	ENOG4105E7W	lamb ycsf family protein
F9277_24585	ENOG4105BZU	Histidine kinase
F9277_24590	ENOG4105CMR	udp-glucose 4-epimerase
F9277_24605	ENOG4105CWB	LysR family transcriptional Regulator
F9277_24615	ENOG4105CD5	CoA-binding domain protein
F9277_24625	ENOG4105CPF	Cell wall formation (By similarity)
F9277_24635	ENOG4108ZJT	translation initiation factor, Sui1
F9277_24645	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
F9277_24685	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
F9277_24690	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
F9277_24705	ENOG4105BZU	Histidine kinase
F9277_24730	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
F9277_24735	ENOG4105E0C	molybdate abc transporter
F9277_24740	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
F9277_24745	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
F9277_24750	ENOG4105WXI	Bacterial OB fold (BOF) protein
F9277_24760	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
F9277_24765	ENOG4105CGF	Aromatic amino acid aminotransferase
F9277_24770	ENOG4105ECQ	AraC Family Transcriptional Regulator
F9277_24775	ENOG4107QI1	Mate efflux family protein
F9277_24780	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
F9277_24785	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
F9277_24840	ENOG4105CXY	transporter
F9277_24845	ENOG4108KX4	response regulator
F9277_24850	ENOG4105BZU	Histidine kinase
F9277_24855	ENOG4105CXY	transporter
F9277_24860	ENOG4105EIP	mannose-6-phosphate isomerase
F9277_24870	ENOG4105IPI	Membrane
F9277_24880	ENOG4105EFX	secretion protein, HlyD family
F9277_24905	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
F9277_24910	ENOG4105K63	Thioredoxin
F9277_24915	ENOG4108ISG	Major Facilitator
F9277_24930	ENOG4105VXR	cytoplasmic protein
F9277_24955	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
F9277_24970	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
F9277_24975	ENOG4105TMB	Formate nitrite transporter
F9277_24980	ENOG4105WZK	nitrite reductase NADPH small subunit
F9277_24985	ENOG4107QZF	nitrite reductase NADPH large subunit
F9277_24990	ENOG4108KHX	Diguanylate cyclase
F9277_25070	ENOG4107ZQN	disulfide bond
F9277_25080	ENOG4105CXG	d-lactate dehydrogenase
F9277_25085	ENOG4105CBN	LysR family transcriptional regulator
F9277_25095	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
F9277_25100	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
F9277_25110	ENOG4105C5W	Aldolase
F9277_25120	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
F9277_25130	ENOG4105C2C	drug resistance transporter, Bcr CflA
F9277_25140	ENOG4105QNF	Outer membrane lipoprotein
F9277_25175	ENOG4105E03	chitinase
F9277_25185	ENOG4105EYH	Exonuclease
F9277_25190	ENOG4107RFY	SbcCD D subunit
F9277_25215	ENOG4107TV1	YD repeat protein
F9277_25230	ENOG4105CS6	Rhs element vgr protein
F9277_25240	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
F9277_25285	ENOG4108ZF3	Phosphatase
F9277_25300	ENOG4106VK6	Flagellar motor protein
F9277_25320	ENOG4105D9P	serine threonine protein kinase
F9277_25345	ENOG4108UYE	Lactoylglutathione lyase
F9277_25350	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
F9277_25360	ENOG4105EXC	Acyl-transferase
F9277_25375	ENOG4105CBC	glutamate synthase
F9277_25385	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
F9277_25390	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
F9277_25445	ENOG4107VQW	regulatoR
F9277_25465	ENOG4105BZU	Histidine kinase
F9277_25475	ENOG4105IPI	Membrane
F9277_25490	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_25500	ENOG4105DS1	cytochrome b561
F9277_25510	ENOG4105DR5	peptidase
F9277_25530	ENOG4105F8J	Adenylate Guanylate cyclase
F9277_25560	ENOG4107QZF	nitrite reductase NADPH large subunit
F9277_25565	ENOG4105D7T	ABC transporter
F9277_25570	ENOG4105DG7	nitrate ABC transporter
F9277_25610	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
F9277_25615	ENOG4105BZU	Histidine kinase
F9277_25620	ENOG4105C44	Serine transporter
F9277_25630	ENOG4105BZU	Histidine kinase
F9277_25650	ENOG4105G6Z	alkaline phosphatase
F9277_25665	ENOG4105ETX	regulatoR
F9277_25695	ENOG4106E5D	Protein of unknown function (DUF461)
F9277_25700	ENOG4105R8A	Heat shock protein
F9277_25715	ENOG4107RUY	(E1 component), alpha subunit
F9277_25720	ENOG4105CPP	Dehydrogenase, E1 component
F9277_25725	ENOG4107QSN	dihydrolipoamide acetyltransferase
F9277_25730	ENOG4105C10	Electron transfer flavoprotein
F9277_25735	ENOG4105BZJ	Electron transfer flavoprotein
F9277_25740	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
F9277_25750	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
F9277_25765	ENOG4105DUM	transcriptional regulator, lysR family
F9277_25775	ENOG4105DMR	ABC, transporter
F9277_25780	ENOG4105GBT	ABC transporter
F9277_25785	ENOG4106PMH	Extracellular solute-binding protein family 3
F9277_25790	ENOG4105E5Z	arginine transporter ATP-binding subunit
F9277_25795	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_25835	ENOG4105C26	Dehydrogenase
F9277_25845	ENOG4105F04	LysR family Transcriptional regulator
F9277_25850	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
F9277_25855	ENOG4105BZU	Histidine kinase
F9277_25860	ENOG4105C1J	atp-dependent rna helicase
F9277_25885	ENOG4105QYW	Excisionase-like protein from lambdoid prophage 14
F9277_25895	ENOG4108I1J	Integrase
F9277_25920	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
F9277_25945	ENOG4107XZC	Restriction modification system DNA (Specificity
F9277_25955	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
F9277_26025	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
F9277_26040	ENOG4107S17	Phosphate-binding protein
F9277_26055	ENOG4105E0F	Histidine kinase
F9277_26060	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
F9277_26065	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
F9277_26070	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
F9277_26075	ENOG4105DWP	Membrane
F9277_26080	ENOG4105DKW	ABC transporter
F9277_26085	ENOG4105BZU	Histidine kinase
F9277_26105	ENOG4105C1J	atp-dependent rna helicase
F9277_26110	ENOG4105BZU	Histidine kinase
F9277_26115	ENOG4105CKI	cobalamin synthesis protein
F9277_26125	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
F9277_26140	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
F9277_26150	ENOG4108Z6Z	Transcriptional regulator
F9277_26155	ENOG4108IPW	abc transporter atp-binding protein
F9277_26160	ENOG4105CM4	permease protein
F9277_26165	ENOG4105DHS	permease protein
F9277_26185	ENOG4108I5U	Uridine phosphorylase
F9277_26190	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
F9277_26200	ENOG4105ETE	Transcriptional regulator (LacI family
F9277_26205	ENOG4108RVA	ribokinase
F9277_26210	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
F9277_26215	ENOG4105CNN	ABC, transporter
F9277_26220	ENOG4105C2J	ABC transporter
F9277_26225	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
F9277_26230	ENOG4108K0B	C-di-gmp phosphodiesterase
F9277_26235	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
F9277_26265	ENOG4106W5V	Membrane
F9277_26305	ENOG4105BZU	Histidine kinase
F9277_26310	ENOG4105CA0	peroxidase
F9277_26315	ENOG4105BZU	Histidine kinase
F9277_26320	ENOG4105BZU	Histidine kinase
F9277_26335	ENOG4107QX8	SPFH domain, Band 7 family protein
F9277_26345	ENOG4108RCM	Nitroreductase
F9277_26350	ENOG4108IJ7	Glycine betaine
F9277_26355	ENOG4108HQS	Glycine betaine
F9277_26365	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
F9277_26370	ENOG4105C26	Dehydrogenase
F9277_26375	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
F9277_26385	ENOG4105BZU	Histidine kinase
F9277_26395	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
F9277_26410	ENOG4105PSQ	Acyl-transferase
F9277_26440	ENOG4108ZG0	Ompa motb domain protein
F9277_26510	ENOG4105EQ2	LysR family Transcriptional regulator
F9277_26515	ENOG4105ENX	hydrolase
F9277_26525	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
F9277_26530	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
F9277_26540	ENOG4108UNF	response regulator
F9277_26545	ENOG4107RGM	aldo keto reductase
F9277_26570	ENOG4105C5A	transporter
F9277_26580	ENOG4105EUJ	GTP cyclohydrolase i
F9277_26590	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
F9277_26595	ENOG4105D06	uba thif-type nad fad binding protein
F9277_26615	ENOG4105KHC	sulfurtransferase
F9277_26620	ENOG4105BZU	Histidine kinase
F9277_26640	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
F9277_26655	ENOG4105DXI	Major Facilitator superfamily
F9277_26660	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
F9277_26665	ENOG4105UYK	outer membrane protein a
F9277_26675	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
F9277_26680	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
F9277_26705	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
F9277_26750	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
F9277_26765	ENOG4108SXK	Transporter Drug Metabolite Exporter family
F9277_26785	ENOG4105E5M	Multidrug resistance protein D
F9277_26790	ENOG4105CR8	Transcriptional regulator
F9277_26800	ENOG4105DR5	peptidase
F9277_26825	ENOG4105DWD	nucleoside recognition domain protein
F9277_26830	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_26840	ENOG4105E0U	tyrosine-specific transport protein
F9277_26865	ENOG4107Z1W	Fructose transport system kinase
F9277_26875	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
F9277_26880	ENOG4105CTS	PTS system mannitol-specific
F9277_26885	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
F9277_26890	ENOG4105FDP	GntR family transcriptional regulator
F9277_26895	ENOG4105DM4	PTS System
F9277_26900	ENOG4105C8I	hydrolase, family 38
F9277_26905	ENOG4105EIP	mannose-6-phosphate isomerase
F9277_26920	ENOG4105KVH	Transcriptional regulator
F9277_26935	ENOG4105D6J	arsenicaL-resistance protein
F9277_26950	ENOG4108V1U	phospholipid-binding protein
F9277_26955	ENOG4105JAB	phenazine biosynthesis protein, phzf family
F9277_26960	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
F9277_26975	ENOG4105EJC	lysr family transcriptional regulator
F9277_27005	ENOG4105JQN	Transcriptional regulator
F9277_27045	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
F9277_27050	ENOG4107R88	Chemotaxis protein (CheV)
F9277_27060	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
F9277_27065	ENOG41090JE	Utilization Protein
F9277_27070	ENOG4105D4P	Coproporphyrinogen iii oxidase
F9277_27075	ENOG4105WQ5	TonB family
F9277_27080	ENOG41090AP	transport protein
F9277_27085	ENOG4106GFD	transport protein
F9277_27095	ENOG4105EHG	Permease protein
F9277_27100	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
F9277_27105	ENOG4105C8Q	Methyl-accepting chemotaxis
F9277_27115	ENOG4105CJ1	ABC, transporter
F9277_27120	ENOG4107QWP	ABC-2 type transporter
F9277_27125	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
F9277_27135	ENOG4105E2D	ec 3.2.1.52
F9277_27140	ENOG4108UHU	Aldolase
F9277_27145	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
F9277_27150	ENOG4108IA2	Sodium pantothenate symporter
F9277_27185	ENOG4108IEG	Formate dehydrogenase Alpha subunit
F9277_27205	ENOG4108IJF	Heavy metal efflux pump, CzcA
F9277_27225	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
F9277_27245	ENOG4107RAN	Peptidase, M16
F9277_27250	ENOG4105CQ0	ABC transporter
F9277_27255	ENOG4105PE1	Receptor
F9277_27275	ENOG4109015	Biopolymer transport protein exbD tolR
F9277_27300	ENOG4105CA0	peroxidase
F9277_27310	ENOG4108HK0	-acetyltransferase
F9277_27325	ENOG4105C5H	ABC transporter
F9277_27350	ENOG4105CNH	Multidrug resistance protein MdtL
F9277_27365	ENOG4105HEI	LysR family (Transcriptional regulator
F9277_27370	ENOG4108M6U	Universal stress protein A
F9277_27380	ENOG4105E98	transcriptional regulator DeoR family
F9277_27395	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
F9277_27400	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
F9277_27405	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
F9277_27420	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
F9277_27435	ENOG4105CKI	cobalamin synthesis protein
F9277_27445	ENOG4105CD3	dihydroorotase
F9277_27455	ENOG4108NRW	Phospholipase, patatin family
F9277_27465	ENOG4105EUB	pirin domain protein
F9277_27470	ENOG4105VEQ	Cold shock protein
F9277_27485	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
F9277_27515	ENOG4105DMQ	Methyltransferase
F9277_27525	ENOG4105BZU	Histidine kinase
F9277_27530	ENOG4105DZ1	carboxypeptidase
F9277_27540	ENOG4105C94	Transporter
F9277_27545	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
F9277_27550	ENOG4105EJC	lysr family transcriptional regulator
F9277_27555	ENOG4105CYM	Glutathione S-transferase
F9277_27565	ENOG4105NAE	bifunctional deaminase-reductase domain protein
F9277_27575	ENOG4107RCH	Diaminopropionate ammonia-lyase
F9277_27610	ENOG4105CHR	reductase
F9277_27635	ENOG4108P3C	
F9277_27650	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
F9277_27660	ENOG4105CK2	sodium dicarboxylate symporter
F9277_27665	ENOG4105CEP	NADH dehydrogenase
F9277_27680	ENOG4105CK1	PTS System
F9277_27685	ENOG4105BZU	Histidine kinase
F9277_27695	ENOG4105KCK	Peptidoglycan-associated lipoprotein
F9277_27715	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
F9277_27720	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
F9277_27725	ENOG4105E2Z	phosphate ABC transporter (Permease
F9277_27730	ENOG4105C8U	phosphate abc transporter
F9277_27735	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
F9277_27745	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
F9277_27750	ENOG4108UW5	maltose o-acetyltransferase
F9277_27760	ENOG4108JJ6	Type I secretion system ATPase
F9277_27770	ENOG41086KC	Transcriptional regulator
F9277_27775	ENOG41086KC	Transcriptional regulator
F9277_27785	ENOG41069D7	Methyl-accepting chemotaxis
F9277_27790	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
F9277_27825	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
F9277_27830	ENOG4105E2Z	phosphate ABC transporter (Permease
F9277_27835	ENOG4105C8U	phosphate abc transporter
F9277_27840	ENOG4107S17	Phosphate-binding protein
F9277_27845	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
F9277_27865	ENOG4107ENK	receptor
F9277_27870	ENOG4105CUG	Oligopeptidase b
F9277_27880	ENOG4105C1J	atp-dependent rna helicase
F9277_27890	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
F9277_27895	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
F9277_27900	ENOG4108XDN	Transcriptional regulator
F9277_27905	ENOG4107SEY	Conserved Protein
F9277_27915	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
F9277_27930	ENOG4106TD9	Diguanylate cyclase
F9277_27940	ENOG4105KK7	inner membrane protein YiaW
F9277_27945	ENOG4105EFX	secretion protein, HlyD family
F9277_27950	ENOG4108V7D	UPF0397 protein
F9277_27955	ENOG4108JJB	ABC transporter
F9277_27975	ENOG4105GXZ	Ferredoxin-type protein NapH
F9277_27980	ENOG4108BGM	Quinol dehydrogenase periplasmic component
F9277_27985	ENOG4108MK9	spermidine N(1)-acetyltransferase
F9277_28000	ENOG4105YE1	PilZ domain
F9277_28015	ENOG4105DAN	ATP-dependent protease
F9277_28025	ENOG4108JQ5	ABC transporter
F9277_28035	ENOG4105CC0	LysR family Transcriptional regulator
F9277_28040	ENOG4105DAA	L-lactate
F9277_28045	ENOG4105DMF	Dehydrogenase
F9277_28055	ENOG4105D64	Mechanosensitive ion channel
F9277_28070	ENOG4107S8C	mandelate racemase muconate lactonizing
F9277_28080	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
F9277_28100	ENOG4105VYW	UPF0251 protein
F9277_28110	ENOG4108HQS	Glycine betaine
F9277_28115	ENOG4108IJ7	Glycine betaine
F9277_28130	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
F9277_28135	ENOG4108M6U	Universal stress protein A
F9277_28140	ENOG4105ETT	transcriptional Regulator, LysR family
F9277_28165	ENOG4105RA2	Membrane
F9277_28180	ENOG4107RH7	Nicotinate phosphoribosyltransferase
F9277_28190	ENOG4108RWI	nicotinamidase
F9277_28195	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
F9277_28205	ENOG4105CH6	catalase
F9277_28225	ENOG4105EIP	mannose-6-phosphate isomerase
F9277_28230	ENOG4105C87	Aminotransferase class I and II
F9277_28235	ENOG4105CI1	PTS System
F9277_28240	ENOG4107P2S	Transcriptional regulator
F9277_28245	ENOG4105N2W	Transcriptional regulator
F9277_28250	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
F9277_28255	ENOG4105E0X	reductase
F9277_28265	ENOG4105CI1	PTS System
F9277_28270	ENOG4107QSE	Dipeptidase
F9277_28275	ENOG4105E66	phosphoriboisomerase A
F9277_28285	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
F9277_28290	ENOG4107YBY	Hydrolase
F9277_28305	ENOG4108KP7	hydrolase
F9277_28310	ENOG4105DW5	Transcriptional regulator
F9277_28320	ENOG4105DM4	PTS System
F9277_28325	ENOG4105CWX	Alpha-1,2-mannosidase
F9277_28330	ENOG4105CWX	Alpha-1,2-mannosidase
F9277_28340	ENOG4105CWX	Alpha-1,2-mannosidase
F9277_28345	ENOG4105CWX	Alpha-1,2-mannosidase
F9277_28360	ENOG4105N14	lysine exporter protein LysE YggA
F9277_28365	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
F9277_28380	ENOG4105W1N	transcriptional regulator
F9277_28385	ENOG4105HEI	LysR family (Transcriptional regulator
F9277_28400	ENOG4105C5H	ABC transporter
F9277_28405	ENOG4105CHF	Glutathione S-transferase
F9277_28410	ENOG4105Q8W	reductase
F9277_28415	ENOG4105HEI	LysR family (Transcriptional regulator
F9277_28420	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
F9277_28425	ENOG4105C5H	ABC transporter
F9277_28440	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase