locus-tag	class	description
BTD91_00015	COG2885	chlorophyll binding
BTD91_00015	COG3047	cAMP biosynthetic process
BTD91_00030	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BTD91_00035	COG0602	queuosine metabolic process
BTD91_00040	COG0561	phosphatase activity
BTD91_00060	COG2828	Protein conserved in bacteria
BTD91_00065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTD91_00070	COG0372	Belongs to the citrate synthase family
BTD91_00075	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BTD91_00110	COG4628	conserved protein (DUF2132)
BTD91_00115	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BTD91_00120	COG0363	glucosamine-6-phosphate deaminase activity
BTD91_00125	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTD91_00130	COG4565	transcriptional regulatory protein
BTD91_00135	COG3290	protein histidine kinase activity
BTD91_00150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTD91_00165	COG1115	amino acid carrier protein
BTD91_00180	COG1115	amino acid carrier protein
BTD91_00200	COG1280	lysine exporter protein (LysE YggA)
BTD91_00205	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BTD91_00215	COG1595	DNA-templated transcription, initiation
BTD91_00230	COG0730	response to heat
BTD91_00275	COG3033	Beta-eliminating lyase
BTD91_00300	COG0010	Belongs to the arginase family
BTD91_00305	COG1166	arginine decarboxylase activity
BTD91_00315	COG1309	transcriptional regulator
BTD91_00320	COG0488	(ABC) transporter
BTD91_00335	COG3097	Belongs to the UPF0267 family
BTD91_00340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BTD91_00345	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BTD91_00365	COG4326	sporulation control protein
BTD91_00375	COG1228	amidohydrolase
BTD91_00380	COG0010	Belongs to the arginase family
BTD91_00385	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BTD91_00390	COG2986	histidine ammonia-lyase
BTD91_00410	COG0247	lactate metabolic process
BTD91_00410	COG0277	FAD linked oxidase domain protein
BTD91_00425	COG2885	chlorophyll binding
BTD91_00445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BTD91_00455	COG1643	Atp-dependent helicase
BTD91_00460	COG0281	malic enzyme
BTD91_00465	COG2949	membrane
BTD91_00470	COG0471	metal ion transport
BTD91_00485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTD91_00500	COG0492	ferredoxin-NADP+ reductase activity
BTD91_00505	COG4988	ABC transporter
BTD91_00510	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BTD91_00520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTD91_00525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTD91_00550	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTD91_00565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTD91_00570	COG3108	Peptidase M15
BTD91_00575	COG2989	Protein conserved in bacteria
BTD91_00600	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTD91_00610	COG3088	subunit of a heme lyase
BTD91_00610	COG4235	cytochrome complex assembly
BTD91_00620	COG1138	Cytochrome C-type biogenesis protein
BTD91_00625	COG3301	Polysulphide reductase, NrfD
BTD91_00630	COG0437	4 iron, 4 sulfur cluster binding
BTD91_00635	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BTD91_00640	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BTD91_00645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTD91_00660	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTD91_00665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTD91_00670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTD91_00690	COG0243	molybdopterin cofactor binding
BTD91_00695	COG0437	4 iron, 4 sulfur cluster binding
BTD91_00700	COG3302	dmso reductase anchor subunit
BTD91_00720	COG0019	diaminopimelate decarboxylase activity
BTD91_00760	COG0322	excinuclease ABC activity
BTD91_00765	COG2197	response regulator
BTD91_00770	COG0417	DNA replication proofreading
BTD91_00780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BTD91_00795	COG1187	pseudouridine synthase activity
BTD91_00800	COG0009	L-threonylcarbamoyladenylate synthase
BTD91_00805	COG0613	PHP domain protein
BTD91_00815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTD91_00820	COG0512	Glutamine amidotransferase of anthranilate synthase
BTD91_00825	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BTD91_00830	COG0134	indole-3-glycerol-phosphate synthase activity
BTD91_00830	COG0135	phosphoribosylanthranilate isomerase activity
BTD91_00835	COG0133	tryptophan synthase activity
BTD91_00840	COG0159	tryptophan synthase activity
BTD91_00845	COG0330	HflC and HflK could
BTD91_00855	COG1301	dicarboxylic acid transport
BTD91_00860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTD91_00880	COG2917	probably involved in intracellular septation
BTD91_00885	COG1607	acyl-coa hydrolase
BTD91_00890	COG2350	Protein conserved in bacteria
BTD91_00900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BTD91_00920	COG1032	radical SAM domain protein
BTD91_00925	COG1396	sequence-specific DNA binding
BTD91_00930	COG3135	benzoate transporter
BTD91_00945	COG0463	Glycosyl transferase, family 2
BTD91_00950	COG0745	RESPONSE REGULATOR receiver
BTD91_00970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTD91_00975	COG0583	DNA-binding transcription factor activity
BTD91_00990	COG5002	protein histidine kinase activity
BTD91_00990	COG0784	Response regulator, receiver
BTD91_01005	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BTD91_01010	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BTD91_01015	COG2885	chlorophyll binding
BTD91_01020	COG0823	Involved in the tonB-independent uptake of proteins
BTD91_01035	COG0811	peptide transport
BTD91_01040	COG0824	Thioesterase
BTD91_01050	COG4890	Cyd operon protein YbgT
BTD91_01055	COG1294	oxidase, subunit
BTD91_01060	COG1271	oxidase subunit
BTD91_01065	COG2255	four-way junction helicase activity
BTD91_01070	COG0632	four-way junction helicase activity
BTD91_01075	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BTD91_01080	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BTD91_01085	COG1801	Protein of unknown function DUF72
BTD91_01090	COG4106	trans-aconitate 2-methyltransferase activity
BTD91_01095	COG0500	methyltransferase
BTD91_01100	COG4067	protein conserved in archaea
BTD91_01100	COG0189	ligase activity
BTD91_01115	COG3383	formate dehydrogenase (NAD+) activity
BTD91_01120	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BTD91_01125	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BTD91_01130	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
BTD91_01135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTD91_01140	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BTD91_01145	COG0745	RESPONSE REGULATOR receiver
BTD91_01150	COG3381	protein complex oligomerization
BTD91_01155	COG1609	Transcriptional regulator
BTD91_01160	COG3070	regulator of competence-specific genes
BTD91_01180	COG0297	glycogen (starch) synthase activity
BTD91_01185	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTD91_01200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BTD91_01210	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BTD91_01215	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BTD91_01220	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BTD91_01225	COG0542	response to heat
BTD91_01230	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BTD91_01235	COG1278	Cold shock
BTD91_01245	COG1187	pseudouridine synthase activity
BTD91_01250	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BTD91_01260	COG1199	ATP-dependent helicase activity
BTD91_01280	COG2850	peptidyl-arginine hydroxylation
BTD91_01285	COG0840	transmembrane signaling receptor activity
BTD91_01290	COG2814	Major facilitator Superfamily
BTD91_01295	COG1770	oligopeptidase
BTD91_01305	COG4160	amino acid transport
BTD91_01330	COG1882	Formate acetyltransferase
BTD91_01340	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BTD91_01345	COG3013	Belongs to the UPF0304 family
BTD91_01350	COG2766	serine protein kinase
BTD91_01355	COG2718	Belongs to the UPF0229 family
BTD91_01360	COG2719	SpoVR family
BTD91_01365	COG0616	signal peptide processing
BTD91_01370	COG1028	Short-chain dehydrogenase reductase Sdr
BTD91_01390	COG0835	chemotaxis
BTD91_01390	COG0784	Response regulator, receiver
BTD91_01395	COG1940	carbohydrate kinase activity
BTD91_01400	COG0469	pyruvate kinase activity
BTD91_01405	COG4667	esterase of the alpha-beta hydrolase superfamily
BTD91_01425	COG1263	PTS System
BTD91_01425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTD91_01430	COG0084	hydrolase, TatD family'
BTD91_01440	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BTD91_01445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTD91_01450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTD91_01475	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTD91_01480	COG0416	fatty acid biosynthetic process
BTD91_01485	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTD91_01490	COG1399	metal-binding, possibly nucleic acid-binding protein
BTD91_01500	COG0564	pseudouridine synthase activity
BTD91_01505	COG1530	ribonuclease E activity
BTD91_01510	COG0659	secondary active sulfate transmembrane transporter activity
BTD91_01515	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BTD91_01520	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BTD91_01525	COG2982	Protein involved in outer membrane biogenesis
BTD91_01530	COG0572	uridine kinase
BTD91_01535	COG0489	protein tyrosine kinase activity
BTD91_01540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTD91_01540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTD91_01550	COG2186	Transcriptional regulator
BTD91_01555	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BTD91_01565	COG0653	protein targeting
BTD91_01570	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTD91_01575	COG3706	GGDEF domain
BTD91_01585	COG3092	negative regulation of chromosome organization
BTD91_01590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BTD91_01595	COG0280	phosphate acetyltransferase
BTD91_01595	COG0857	belongs to the CobB CobQ family
BTD91_01600	COG0435	Glutathione S-transferase
BTD91_01610	COG0444	Belongs to the ABC transporter superfamily
BTD91_01615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTD91_01620	COG0601	transmembrane transport
BTD91_01630	COG0314	molybdopterin synthase activity
BTD91_01635	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BTD91_01640	COG0315	cyclic pyranopterin monophosphate synthase activity
BTD91_01645	COG0521	Mo-molybdopterin cofactor biosynthetic process
BTD91_01650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BTD91_01655	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BTD91_01660	COG2198	Histidine kinase
BTD91_01665	COG2204	response regulator
BTD91_01670	COG0556	nucleotide-excision repair
BTD91_01680	COG4657	Part of a membrane complex involved in electron transport
BTD91_01685	COG2878	Part of a membrane complex involved in electron transport
BTD91_01690	COG4656	Part of a membrane complex involved in electron transport
BTD91_01695	COG4658	electron transport chain
BTD91_01700	COG4659	FMN binding
BTD91_01705	COG4660	Part of a membrane complex involved in electron transport
BTD91_01710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BTD91_01715	COG0346	lactoylglutathione lyase activity
BTD91_01725	COG2885	chlorophyll binding
BTD91_01735	COG2056	Na+-H+ antiporter family
BTD91_01745	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BTD91_01765	COG1012	belongs to the aldehyde dehydrogenase family
BTD91_01765	COG1454	alcohol dehydrogenase
BTD91_01770	COG2095	MarC family integral membrane protein
BTD91_01775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTD91_01780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTD91_01785	COG1757	Na H antiporter
BTD91_01800	COG3081	Nucleoid-associated protein
BTD91_01805	COG3082	Protein of unknown function (DUF1414)
BTD91_01810	COG3083	sulfuric ester hydrolase activity
BTD91_01820	COG0840	transmembrane signaling receptor activity
BTD91_01825	COG0123	including yeast histone deacetylase and acetoin utilization protein
BTD91_01840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTD91_01845	COG0778	Nitroreductase
BTD91_01850	COG1902	pentaerythritol trinitrate reductase activity
BTD91_01850	COG0446	pyridine nucleotide-disulphide oxidoreductase
BTD91_01855	COG0616	signal peptide processing
BTD91_01860	COG0252	asparaginase activity
BTD91_01865	COG3139	Protein of unknown function (DUF1315)
BTD91_01875	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTD91_01880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTD91_01895	COG2226	methyltransferase
BTD91_01915	COG1785	Belongs to the alkaline phosphatase family
BTD91_01920	COG2983	Belongs to the UPF0260 family
BTD91_01930	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BTD91_01935	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BTD91_01945	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BTD91_01950	COG2832	Protein of unknown function (DUF454)
BTD91_01960	COG0745	RESPONSE REGULATOR receiver
BTD91_01965	COG0583	DNA-binding transcription factor activity
BTD91_01970	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BTD91_01975	COG1286	toxin biosynthetic process
BTD91_01980	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BTD91_01985	COG0285	dihydrofolate synthase activity
BTD91_01990	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BTD91_01995	COG0101	tRNA pseudouridine synthase activity
BTD91_02005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTD91_02010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTD91_02015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTD91_02025	COG0431	NADPH-dependent FMN reductase
BTD91_02035	COG3101	peptidyl-lysine hydroxylation
BTD91_02040	COG2860	membrane
BTD91_02045	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BTD91_02060	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BTD91_02065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTD91_02070	COG0583	DNA-binding transcription factor activity
BTD91_02075	COG2951	lytic endotransglycosylase activity
BTD91_02080	COG3100	YcgL domain-containing protein
BTD91_02085	COG0850	regulation of cytokinetic process
BTD91_02090	COG2894	cell division
BTD91_02095	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BTD91_02100	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BTD91_02105	COG0318	PFAM AMP-dependent synthetase and ligase
BTD91_02110	COG0596	Alpha beta hydrolase
BTD91_02125	COG1214	PFAM Peptidase M22, glycoprotease
BTD91_02130	COG1199	ATP-dependent helicase activity
BTD91_02135	COG0788	formyltetrahydrofolate deformylase activity
BTD91_02140	COG3102	Protein conserved in bacteria
BTD91_02165	COG1918	ferrous iron import across plasma membrane
BTD91_02175	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BTD91_02180	COG1121	(ABC) transporter
BTD91_02185	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTD91_02195	COG0045	succinate-CoA ligase (ADP-forming) activity
BTD91_02200	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTD91_02205	COG0567	Dehydrogenase, E1 component
BTD91_02210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTD91_02215	COG1053	succinate dehydrogenase
BTD91_02220	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BTD91_02230	COG0372	Belongs to the citrate synthase family
BTD91_02235	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BTD91_02245	COG0033	Phosphoglucomutase
BTD91_02250	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BTD91_02255	COG0596	Alpha beta hydrolase
BTD91_02280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTD91_02285	COG1263	PTS System
BTD91_02285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTD91_02285	COG2190	(PTS) system
BTD91_02290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BTD91_02295	COG1846	Transcriptional regulator
BTD91_02295	COG1940	carbohydrate kinase activity
BTD91_02300	COG4651	solute:proton antiporter activity
BTD91_02300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTD91_02305	COG0367	asparagine synthase
BTD91_02310	COG0250	Participates in transcription elongation, termination and antitermination
BTD91_02315	COG3104	oligopeptide transport
BTD91_02320	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BTD91_02325	COG0563	adenylate kinase activity
BTD91_02330	COG0326	Molecular chaperone. Has ATPase activity
BTD91_02335	COG3710	Transcriptional regulator
BTD91_02355	COG0622	Phosphoesterase
BTD91_02380	COG1090	epimerase
BTD91_02385	COG0300	oxidoreductase activity
BTD91_02390	COG3118	belongs to the thioredoxin family
BTD91_02395	COG0330	HflC and HflK could
BTD91_02400	COG1585	Membrane protein implicated in regulation of membrane protease activity
BTD91_02405	COG0789	Transcriptional regulator
BTD91_02420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BTD91_02480	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BTD91_02485	COG3115	cell septum assembly
BTD91_02490	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BTD91_02500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTD91_02505	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BTD91_02510	COG2190	(PTS) system
BTD91_02515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTD91_02520	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTD91_02525	COG2837	iron assimilation
BTD91_02555	COG0189	ligase activity
BTD91_02565	COG1393	Belongs to the ArsC family
BTD91_02570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTD91_02585	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BTD91_02590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTD91_02595	COG2716	regulation of RNA biosynthetic process
BTD91_02600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTD91_02615	COG4783	chaperone-mediated protein folding
BTD91_02620	COG1393	Belongs to the ArsC family
BTD91_02640	COG2233	PERMEase
BTD91_02650	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BTD91_02655	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BTD91_02660	COG0121	glutamine amidotransferase
BTD91_02665	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BTD91_02670	COG1960	acyl-CoA dehydrogenase activity
BTD91_02680	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTD91_02685	COG0328	RNA-DNA hybrid ribonuclease activity
BTD91_02695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTD91_02700	COG0741	lytic transglycosylase activity
BTD91_02700	COG1388	LysM domain
BTD91_02710	COG3021	interspecies interaction between organisms
BTD91_02715	COG0347	Belongs to the P(II) protein family
BTD91_02725	COG0037	tRNA processing
BTD91_02730	COG0825	malonyl-CoA metabolic process
BTD91_02735	COG0587	DNA-directed DNA polymerase activity
BTD91_02740	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BTD91_02750	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTD91_02755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTD91_02760	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTD91_02765	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BTD91_02775	COG0750	zinc metalloprotease
BTD91_02785	COG0575	Belongs to the CDS family
BTD91_02790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BTD91_02795	COG0233	cytoplasmic translational termination
BTD91_02800	COG0528	UMP kinase activity
BTD91_02805	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BTD91_02810	COG0052	Belongs to the universal ribosomal protein uS2 family
BTD91_02815	COG0024	Methionine aminopeptidase
BTD91_02820	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BTD91_02830	COG0564	pseudouridine synthase activity
BTD91_02835	COG3098	single-species biofilm formation
BTD91_02855	COG1671	Belongs to the UPF0178 family
BTD91_02860	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BTD91_02870	COG0254	rRNA binding
BTD91_02875	COG1720	tRNA m6t6A37 methyltransferase activity
BTD91_02880	COG0442	prolyl-tRNA aminoacylation
BTD91_02915	COG0366	Alpha amylase catalytic
BTD91_02920	COG1263	PTS System
BTD91_02920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTD91_02925	COG1609	Transcriptional regulator
BTD91_02935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTD91_02940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTD91_02945	COG2011	ABC-type metal ion transport system permease component
BTD91_02950	COG1464	Belongs to the NlpA lipoprotein family
BTD91_02955	COG4580	involved in the transport of maltose and maltodextrins
BTD91_02960	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BTD91_02970	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BTD91_02970	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BTD91_02985	COG1611	Belongs to the LOG family
BTD91_02990	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTD91_02995	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BTD91_03010	COG0583	DNA-binding transcription factor activity
BTD91_03015	COG0301	tRNA thio-modification
BTD91_03015	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTD91_03025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BTD91_03030	COG1722	exodeoxyribonuclease VII activity
BTD91_03035	COG0142	geranyltranstransferase activity
BTD91_03040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BTD91_03050	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BTD91_03055	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BTD91_03060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTD91_03080	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTD91_03080	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTD91_03085	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BTD91_03090	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BTD91_03095	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BTD91_03105	COG1073	alpha beta
BTD91_03110	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BTD91_03115	COG2252	PERMEase
BTD91_03120	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTD91_03150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTD91_03155	COG1609	Transcriptional regulator
BTD91_03160	COG2017	converts alpha-aldose to the beta-anomer
BTD91_03170	COG1085	galactose-1-phosphate uridylyltransferase
BTD91_03175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BTD91_03180	COG1609	Transcriptional regulator
BTD91_03190	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BTD91_03190	COG0519	Catalyzes the synthesis of GMP from XMP
BTD91_03195	COG0517	IMP dehydrogenase activity
BTD91_03195	COG0516	GMP reductase activity
BTD91_03205	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BTD91_03220	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BTD91_03225	COG0804	urea catabolic process
BTD91_03230	COG0832	Belongs to the urease beta subunit family
BTD91_03235	COG0831	urea catabolic process
BTD91_03280	COG1160	GTP binding
BTD91_03285	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTD91_03290	COG2976	Protein conserved in bacteria
BTD91_03295	COG0124	histidyl-tRNA synthetase
BTD91_03300	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BTD91_03310	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BTD91_03315	COG0105	UTP biosynthetic process
BTD91_03320	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BTD91_03325	COG2975	iron-sulfur cluster assembly
BTD91_03335	COG0443	Heat shock 70 kDa protein
BTD91_03340	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BTD91_03350	COG0822	iron-sulfur transferase activity
BTD91_03355	COG1104	cysteine desulfurase activity
BTD91_03360	COG1959	2 iron, 2 sulfur cluster binding
BTD91_03365	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BTD91_03370	COG0483	inositol monophosphate 1-phosphatase activity
BTD91_03375	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTD91_03380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTD91_03385	COG1862	Preprotein translocase
BTD91_03390	COG0343	queuine tRNA-ribosyltransferase activity
BTD91_03395	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BTD91_03400	COG0517	IMP dehydrogenase activity
BTD91_03405	COG0840	transmembrane signaling receptor activity
BTD91_03410	COG0583	DNA-binding transcription factor activity
BTD91_03415	COG0450	alkyl hydroperoxide reductase
BTD91_03420	COG3142	Participates in the control of copper homeostasis
BTD91_03425	COG0704	Plays a role in the regulation of phosphate uptake
BTD91_03430	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BTD91_03445	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BTD91_03450	COG0248	Ppx GppA phosphatase
BTD91_03465	COG0745	RESPONSE REGULATOR receiver
BTD91_03470	COG2974	May be involved in recombination
BTD91_03475	COG0826	peptidase U32
BTD91_03480	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BTD91_03485	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BTD91_03525	COG0542	response to heat
BTD91_03535	COG0564	pseudouridine synthase activity
BTD91_03540	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTD91_03545	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BTD91_03550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTD91_03555	COG1605	Chorismate mutase
BTD91_03555	COG0077	Prephenate dehydratase
BTD91_03560	COG5001	Diguanylate cyclase
BTD91_03565	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BTD91_03570	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BTD91_03580	COG0488	(ABC) transporter
BTD91_03590	COG0739	heme binding
BTD91_03595	COG1605	Chorismate mutase
BTD91_03595	COG0287	Prephenate dehydrogenase
BTD91_03600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTD91_03610	COG1737	Transcriptional regulator
BTD91_03620	COG2971	BadF BadG BcrA BcrD
BTD91_03625	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BTD91_03630	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BTD91_03640	COG1966	Carbon starvation protein
BTD91_03645	COG3275	phosphorelay sensor kinase activity
BTD91_03650	COG3279	Response regulator of the LytR AlgR family
BTD91_03655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BTD91_03660	COG1047	Peptidyl-prolyl cis-trans
BTD91_03670	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BTD91_03675	COG0196	riboflavin kinase activity
BTD91_03680	COG0728	peptidoglycan biosynthetic process
BTD91_03685	COG0268	Binds directly to 16S ribosomal RNA
BTD91_03690	COG0640	Transcriptional regulator
BTD91_03695	COG0583	DNA-binding transcription factor activity
BTD91_03700	COG1283	sodium-dependent phosphate transmembrane transporter activity
BTD91_03705	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BTD91_03715	COG1122	ATPase activity
BTD91_03725	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BTD91_03735	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BTD91_03775	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BTD91_03805	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BTD91_03810	COG0730	response to heat
BTD91_03820	COG0494	nUDIX hydrolase
BTD91_03860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BTD91_03865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BTD91_03870	COG4974	Belongs to the 'phage' integrase family
BTD91_03875	COG0716	FMN binding
BTD91_03885	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BTD91_03890	COG0513	Belongs to the DEAD box helicase family
BTD91_03895	COG3022	response to hydroperoxide
BTD91_03900	COG1115	amino acid carrier protein
BTD91_03915	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BTD91_03920	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BTD91_03925	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
BTD91_03930	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BTD91_03935	COG0083	homoserine kinase activity
BTD91_03950	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BTD91_03955	COG0745	RESPONSE REGULATOR receiver
BTD91_03965	COG2198	Histidine kinase
BTD91_03965	COG0784	Response regulator, receiver
BTD91_03965	COG5002	protein histidine kinase activity
BTD91_03970	COG2203	Gaf domain
BTD91_03970	COG3706	GGDEF domain
BTD91_03970	COG4251	negative regulation of phosphorylation
BTD91_03970	COG5001	Diguanylate cyclase
BTD91_03975	COG1242	4 iron, 4 sulfur cluster binding
BTD91_03980	COG0070	glutamate synthase
BTD91_03980	COG0069	glutamate synthase activity
BTD91_03980	COG0067	glutamate synthase
BTD91_03990	COG0070	glutamate synthase
BTD91_03990	COG0067	glutamate synthase
BTD91_03990	COG0069	glutamate synthase activity
BTD91_03995	COG0493	'glutamate synthase
BTD91_04005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BTD91_04015	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTD91_04020	COG2860	membrane
BTD91_04025	COG0583	DNA-binding transcription factor activity
BTD91_04030	COG0730	response to heat
BTD91_04035	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BTD91_04040	COG0505	Belongs to the CarA family
BTD91_04045	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BTD91_04050	COG0494	nUDIX hydrolase
BTD91_04055	COG0653	protein targeting
BTD91_04060	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BTD91_04065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BTD91_04070	COG0849	cell division
BTD91_04075	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BTD91_04080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BTD91_04085	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BTD91_04090	COG0772	Belongs to the SEDS family
BTD91_04095	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BTD91_04100	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTD91_04105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BTD91_04110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BTD91_04115	COG0768	penicillin binding
BTD91_04120	COG3116	cell division
BTD91_04125	COG0275	rRNA processing
BTD91_04135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BTD91_04150	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BTD91_04160	COG2969	positive regulation of protein catabolic process
BTD91_04165	COG0625	glutathione transferase activity
BTD91_04170	COG2857	Cytochrome c1
BTD91_04175	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTD91_04180	COG0723	plastoquinol--plastocyanin reductase activity
BTD91_04185	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BTD91_04195	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BTD91_04200	COG3105	Protein conserved in bacteria
BTD91_04210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTD91_04225	COG3150	esterase
BTD91_04235	COG3151	Protein conserved in bacteria
BTD91_04240	COG0494	nUDIX hydrolase
BTD91_04245	COG1538	Outer membrane efflux protein
BTD91_04250	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BTD91_04250	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BTD91_04255	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BTD91_04265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTD91_04270	COG3025	triphosphatase activity
BTD91_04275	COG1392	Phosphate transport regulator
BTD91_04280	COG0306	phosphate transporter
BTD91_04285	COG4991	sh3 domain protein
BTD91_04295	COG3267	Type II secretory pathway component ExeA
BTD91_04295	COG3409	Peptidoglycan-binding domain 1 protein
BTD91_04300	COG0617	tRNA 3'-terminal CCA addition
BTD91_04305	COG1968	undecaprenyl-diphosphatase activity
BTD91_04310	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BTD91_04315	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BTD91_04320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BTD91_04325	COG0596	Alpha beta hydrolase
BTD91_04330	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BTD91_04335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BTD91_04340	COG1610	YqeY-like protein
BTD91_04360	COG2873	o-acetylhomoserine
BTD91_04415	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BTD91_04450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BTD91_04455	COG1349	DNA-binding transcription factor activity
BTD91_04460	COG0469	pyruvate kinase activity
BTD91_04470	COG0028	Belongs to the TPP enzyme family
BTD91_04475	COG1022	Amp-dependent synthetase and ligase
BTD91_04510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BTD91_04515	COG0473	3-isopropylmalate dehydrogenase activity
BTD91_04520	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BTD91_04525	COG0066	3-isopropylmalate dehydratase activity
BTD91_04540	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BTD91_04545	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BTD91_04550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTD91_04555	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BTD91_04560	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BTD91_04565	COG2967	ApaG domain
BTD91_04580	COG3610	response to peptide
BTD91_04585	COG2966	Psort location CytoplasmicMembrane, score
BTD91_04590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BTD91_04595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BTD91_04600	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BTD91_04605	COG0142	geranyltranstransferase activity
BTD91_04615	COG0039	L-malate dehydrogenase activity
BTD91_04620	COG1438	arginine binding
BTD91_04635	COG0589	response to stress
BTD91_04640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTD91_04655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BTD91_04660	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BTD91_04665	COG0312	modulator of DNA gyrase
BTD91_04670	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTD91_04685	COG0424	maF-like protein
BTD91_04690	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BTD91_04695	COG1792	Involved in formation and maintenance of cell shape
BTD91_04700	COG1077	Cell shape determining protein MreB Mrl
BTD91_04730	COG2165	general secretion pathway protein
BTD91_04735	COG2165	general secretion pathway protein
BTD91_04745	COG1459	type II secretion system
BTD91_04750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTD91_04760	COG3267	Type II secretory pathway component ExeA
BTD91_04760	COG3409	Peptidoglycan-binding domain 1 protein
BTD91_04785	COG2199	diguanylate cyclase activity
BTD91_04785	COG2200	EAL domain
BTD91_04790	COG0629	single-stranded DNA binding
BTD91_04795	COG2197	response regulator
BTD91_04805	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BTD91_04815	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BTD91_04820	COG0527	aspartate kinase activity
BTD91_04825	COG1410	methionine synthase
BTD91_04825	COG0646	methionine synthase
BTD91_04905	COG0175	sulfate reduction
BTD91_04910	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTD91_04915	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BTD91_04935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTD91_04940	COG0735	belongs to the Fur family
BTD91_04950	COG0166	Belongs to the GPI family
BTD91_04955	COG0432	Pfam Uncharacterised protein family UPF0047
BTD91_04960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTD91_04975	COG0359	binds to the 23S rRNA
BTD91_04985	COG0360	Binds together with S18 to 16S ribosomal RNA
BTD91_04990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTD91_04995	COG0557	exoribonuclease II activity
BTD91_05000	COG0402	S-adenosylhomocysteine deaminase activity
BTD91_05005	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BTD91_05010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BTD91_05015	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BTD91_05020	COG0330	HflC and HflK could
BTD91_05025	COG0330	HflC and HflK could
BTD91_05030	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTD91_05035	COG1923	regulation of RNA biosynthetic process
BTD91_05040	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BTD91_05045	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BTD91_05050	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTD91_05055	COG0802	atpase or kinase
BTD91_05060	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BTD91_05145	COG1162	GTPase activity
BTD91_05155	COG0471	metal ion transport
BTD91_05155	COG0490	domain, Protein
BTD91_05170	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BTD91_05175	COG1053	succinate dehydrogenase
BTD91_05180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BTD91_05185	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BTD91_05195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BTD91_05200	COG1509	lysine 2,3-aminomutase activity
BTD91_05215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BTD91_05230	COG5002	protein histidine kinase activity
BTD91_05230	COG5001	Diguanylate cyclase
BTD91_05230	COG3447	MASE1 domain protein
BTD91_05255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BTD91_05265	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BTD91_05270	COG0534	Mate efflux family protein
BTD91_05275	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BTD91_05280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTD91_05285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BTD91_05285	COG3153	acetyltransferase
BTD91_05300	COG1216	Glycosyl transferase, family 2
BTD91_05305	COG1216	Glycosyl transferase, family 2
BTD91_05315	COG0297	glycogen (starch) synthase activity
BTD91_05325	COG0110	maltose O-acetyltransferase activity
BTD91_05335	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BTD91_05360	COG2271	Major facilitator Superfamily
BTD91_05365	COG0584	glycerophosphoryl diester phosphodiesterase
BTD91_05380	COG1596	polysaccharide export
BTD91_05400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTD91_05425	COG1215	transferase activity, transferring glycosyl groups
BTD91_05435	COG1682	transport, permease protein
BTD91_05465	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTD91_05470	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BTD91_05480	COG1045	serine acetyltransferase
BTD91_05485	COG4942	peptidase
BTD91_05505	COG1560	Kdo2-lipid A biosynthetic process
BTD91_05515	COG0438	transferase activity, transferring glycosyl groups
BTD91_05535	COG1519	Transferase
BTD91_05540	COG3642	lipopolysaccharide core region biosynthetic process
BTD91_05545	COG0859	PFAM glycosyl transferase family 9
BTD91_05555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BTD91_05565	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTD91_05570	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BTD91_05575	COG2003	Belongs to the UPF0758 family
BTD91_05585	COG1309	transcriptional regulator
BTD91_05590	COG1560	Kdo2-lipid A biosynthetic process
BTD91_05595	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BTD91_05600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BTD91_05605	COG1561	YicC-like family, N-terminal region
BTD91_05610	COG1278	Cold shock
BTD91_05620	COG2252	PERMEase
BTD91_05625	COG0194	GDP metabolic process
BTD91_05630	COG1758	RNA polymerase activity
BTD91_05635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTD91_05640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTD91_05655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BTD91_05670	COG1757	Na H antiporter
BTD91_05680	COG2183	response to ionizing radiation
BTD91_05690	COG0596	Alpha beta hydrolase
BTD91_05695	COG1040	competence protein
BTD91_05700	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BTD91_05700	COG0316	Belongs to the HesB IscA family
BTD91_05705	COG0494	nUDIX hydrolase
BTD91_05710	COG1218	3'(2'),5'-bisphosphate nucleotidase
BTD91_05720	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BTD91_05725	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BTD91_05730	COG3156	type II secretion system protein K
BTD91_05735	COG4795	General secretion pathway protein
BTD91_05740	COG2165	general secretion pathway protein
BTD91_05745	COG2165	general secretion pathway protein
BTD91_05750	COG2165	general secretion pathway protein
BTD91_05755	COG1459	type II secretion system
BTD91_05760	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTD91_05770	COG3031	protein transport across the cell outer membrane
BTD91_05775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BTD91_05785	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BTD91_05795	COG0456	acetyltransferase
BTD91_05800	COG1490	D-aminoacyl-tRNA deacylase activity
BTD91_05805	COG1295	ribonuclease BN
BTD91_05820	COG1217	gtp-binding protein TYPA
BTD91_05825	COG0174	glutamine synthetase
BTD91_05835	COG3852	Histidine kinase
BTD91_05860	COG3078	GTPase activator activity
BTD91_05885	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTD91_05885	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTD91_05900	COG0084	hydrolase, TatD family'
BTD91_05905	COG0805	protein transport
BTD91_05910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTD91_05915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTD91_05920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BTD91_05925	COG3165	ubiquinone biosynthetic process from chorismate
BTD91_05930	COG2226	methyltransferase
BTD91_05935	COG1322	Protein conserved in bacteria
BTD91_05945	COG2081	HI0933 family
BTD91_05955	COG1528	Iron-storage protein
BTD91_05960	COG0589	response to stress
BTD91_05975	COG0742	ribosomal rna small subunit methyltransferase
BTD91_05980	COG5002	protein histidine kinase activity
BTD91_05980	COG5001	Diguanylate cyclase
BTD91_05985	COG1522	sequence-specific DNA binding
BTD91_05995	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BTD91_06000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTD91_06010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTD91_06015	COG0601	transmembrane transport
BTD91_06065	COG1309	transcriptional regulator
BTD91_06070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTD91_06075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTD91_06080	COG2960	long-chain fatty acid transporting porin activity
BTD91_06085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BTD91_06090	COG0583	DNA-binding transcription factor activity
BTD91_06140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTD91_06145	COG1739	Uncharacterized protein family UPF0029
BTD91_06150	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTD91_06150	COG1024	Enoyl-CoA hydratase
BTD91_06155	COG0183	Belongs to the thiolase family
BTD91_06160	COG0604	alcohol dehydrogenase
BTD91_06175	COG0425	Belongs to the sulfur carrier protein TusA family
BTD91_06185	COG2119	membrane
BTD91_06190	COG0752	glycyl-tRNA synthetase alpha subunit
BTD91_06195	COG0751	glycine-tRNA ligase activity
BTD91_06200	COG0366	Alpha amylase catalytic
BTD91_06205	COG3977	Valine--pyruvate aminotransferase
BTD91_06215	COG0187	DNA topoisomerase II activity
BTD91_06220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BTD91_06225	COG0592	DNA-directed DNA polymerase activity
BTD91_06230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTD91_06245	COG1126	abc transporter atp-binding protein
BTD91_06250	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BTD91_06255	COG0594	ribonuclease P activity
BTD91_06260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BTD91_06265	COG0706	membrane insertase activity
BTD91_06275	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BTD91_06280	COG0445	tRNA wobble uridine modification
BTD91_06285	COG0357	Ribosomal RNA small subunit methyltransferase G
BTD91_06290	COG1192	Involved in chromosome partitioning
BTD91_06295	COG1475	DNA binding
BTD91_06300	COG3312	ion transport
BTD91_06315	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BTD91_06320	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BTD91_06325	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BTD91_06330	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BTD91_06335	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BTD91_06340	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BTD91_06350	COG3706	GGDEF domain
BTD91_06355	COG2814	Major facilitator Superfamily
BTD91_06360	COG0583	DNA-binding transcription factor activity
BTD91_06370	COG0129	dihydroxy-acid dehydratase activity
BTD91_06375	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTD91_06380	COG3978	acetolactate synthase activity
BTD91_06390	COG0606	chelatase, subunit chli
BTD91_06400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BTD91_06405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTD91_06415	COG3084	Protein conserved in bacteria
BTD91_06425	COG4326	sporulation control protein
BTD91_06430	COG1272	protein, Hemolysin III
BTD91_06440	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTD91_06445	COG0569	domain protein
BTD91_06450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTD91_06450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTD91_06460	COG0242	peptide deformylase activity
BTD91_06470	COG0758	DNA mediated transformation
BTD91_06475	COG2922	Belongs to the Smg family
BTD91_06480	COG0551	DNA topoisomerase type I activity
BTD91_06485	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTD91_06490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTD91_06495	COG0009	L-threonylcarbamoyladenylate synthase
BTD91_06500	COG0408	coproporphyrinogen oxidase activity
BTD91_06505	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BTD91_06515	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTD91_06555	COG2132	Multicopper oxidase
BTD91_06565	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BTD91_06575	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BTD91_06580	COG2104	thiamine diphosphate biosynthetic process
BTD91_06585	COG2022	thiamine diphosphate biosynthetic process
BTD91_06595	COG0006	proline dipeptidase activity
BTD91_06595	COG0006	proline dipeptidase activity
BTD91_06605	COG2814	Major facilitator Superfamily
BTD91_06625	COG3220	belongs to the UPF0276 family
BTD91_06635	COG0210	DNA helicase
BTD91_06645	COG0405	Gamma-glutamyltransferase
BTD91_06650	COG1280	lysine exporter protein (LysE YggA)
BTD91_06660	COG2962	Rard protein
BTD91_06665	COG0514	ATP-dependent DNA helicase (RecQ)
BTD91_06675	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BTD91_06680	COG0248	Ppx GppA phosphatase
BTD91_06685	COG0513	Belongs to the DEAD box helicase family
BTD91_06690	COG3118	belongs to the thioredoxin family
BTD91_06705	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BTD91_06710	COG2871	sodium ion transport
BTD91_06780	COG2959	enzyme of heme biosynthesis
BTD91_06785	COG1587	Uroporphyrinogen-III synthase
BTD91_06790	COG0181	hydroxymethylbilane synthase activity
BTD91_06800	COG1965	Belongs to the frataxin family
BTD91_06810	COG0019	diaminopimelate decarboxylase activity
BTD91_06815	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BTD91_06825	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BTD91_06830	COG1011	Hydrolase
BTD91_06835	COG2200	EAL domain
BTD91_06835	COG2199	diguanylate cyclase activity
BTD91_06835	COG3287	FIST C domain
BTD91_06840	COG3148	PFAM DTW domain containing protein
BTD91_06855	COG0561	phosphatase activity
BTD91_06860	COG2267	carboxylic ester hydrolase activity
BTD91_06865	COG1280	lysine exporter protein (LysE YggA)
BTD91_06870	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BTD91_06875	COG0640	Transcriptional regulator
BTD91_06880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BTD91_06915	COG2095	MarC family integral membrane protein
BTD91_06925	COG0742	ribosomal rna small subunit methyltransferase
BTD91_06930	COG0552	protein localization to endoplasmic reticulum
BTD91_06935	COG2884	Cell division ATP-binding protein ftsE
BTD91_06940	COG2177	Part of the ABC transporter FtsEX involved in
BTD91_06950	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BTD91_06955	COG0705	Rhomboid family
BTD91_06960	COG1580	Controls the rotational direction of flagella during chemotaxis
BTD91_06965	COG3161	chorismate lyase activity
BTD91_06970	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BTD91_06975	COG2937	Belongs to the GPAT DAPAT family
BTD91_06980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BTD91_06985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BTD91_06990	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BTD91_06995	COG0534	Mate efflux family protein
BTD91_07000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTD91_07020	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTD91_07035	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BTD91_07115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTD91_07125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BTD91_07135	COG1072	(Pantothenic acid kinase))
BTD91_07160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTD91_07165	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTD91_07170	COG0250	Participates in transcription elongation, termination and antitermination
BTD91_07180	COG0081	regulation of translation
BTD91_07185	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BTD91_07190	COG0222	ribosome binding
BTD91_07205	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BTD91_07210	COG2816	NAD+ diphosphatase activity
BTD91_07220	COG1573	uracil-dna glycosylase
BTD91_07230	COG3068	Protein conserved in bacteria
BTD91_07235	COG1253	flavin adenine dinucleotide binding
BTD91_07250	COG0151	Belongs to the GarS family
BTD91_07255	COG0138	bifunctional purine biosynthesis protein purh
BTD91_07265	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BTD91_07270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTD91_07275	COG2264	protein methyltransferase activity
BTD91_07280	COG0439	Biotin carboxylase
BTD91_07285	COG0511	ligase activity, forming carbon-carbon bonds
BTD91_07290	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BTD91_07310	COG2814	Major facilitator Superfamily
BTD91_07315	COG2205	protein histidine kinase activity
BTD91_07315	COG2198	Histidine kinase
BTD91_07315	COG0784	Response regulator, receiver
BTD91_07330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTD91_07340	COG3263	regulation of cellular component size
BTD91_07350	COG4232	protein-disulfide reductase activity
BTD91_07355	COG1438	arginine binding
BTD91_07360	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BTD91_07365	COG0540	Belongs to the ATCase OTCase family
BTD91_07370	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BTD91_07385	COG1288	antiporter activity
BTD91_07390	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BTD91_07395	COG1027	Aspartate ammonia-lyase
BTD91_07405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BTD91_07410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTD91_07415	COG2205	protein histidine kinase activity
BTD91_07420	COG0745	RESPONSE REGULATOR receiver
BTD91_07430	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTD91_07440	COG0149	triose-phosphate isomerase activity
BTD91_07450	COG3152	Membrane
BTD91_07465	COG1494	fructose-1,6-bisphosphatase
BTD91_07470	COG3074	FtsZ-dependent cytokinesis
BTD91_07475	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BTD91_07480	COG1575	Belongs to the MenA family. Type 1 subfamily
BTD91_07485	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BTD91_07490	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BTD91_07500	COG1609	Transcriptional regulator
BTD91_07505	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BTD91_07510	COG0254	rRNA binding
BTD91_07515	COG0281	malic enzyme
BTD91_07520	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
BTD91_07525	COG0626	cystathionine gamma-synthase activity
BTD91_07530	COG0527	aspartate kinase activity
BTD91_07530	COG0460	homoserine dehydrogenase
BTD91_07535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTD91_07545	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BTD91_07550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTD91_07555	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BTD91_07570	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BTD91_07570	COG0165	Argininosuccinate lyase
BTD91_07580	COG0251	oxidation-reduction process
BTD91_07585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTD91_07590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTD91_07590	COG0678	peroxiredoxin activity
BTD91_07600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BTD91_07635	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BTD91_07645	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BTD91_07650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BTD91_07655	COG0546	phosphoglycolate phosphatase activity
BTD91_07660	COG0180	Tryptophanyl-tRNA synthetase
BTD91_07670	COG0512	Glutamine amidotransferase of anthranilate synthase
BTD91_07675	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTD91_07685	COG1012	belongs to the aldehyde dehydrogenase family
BTD91_07695	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTD91_07700	COG3954	Phosphoribulokinase
BTD91_07705	COG3089	Belongs to the UPF0270 family
BTD91_07710	COG0429	hydrolase of the alpha beta-hydrolase fold
BTD91_07720	COG0488	(ABC) transporter
BTD91_07725	COG2249	NAD(P)H dehydrogenase (quinone) activity
BTD91_07740	COG1047	Peptidyl-prolyl cis-trans
BTD91_07745	COG1446	asparaginase
BTD91_07750	COG2900	Belongs to the SlyX family
BTD91_07760	COG0545	Peptidyl-prolyl cis-trans isomerase
BTD91_07765	COG2964	Protein conserved in bacteria
BTD91_07770	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BTD91_07775	COG2923	Belongs to the DsrF TusC family
BTD91_07795	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTD91_07800	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTD91_07810	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BTD91_07815	COG0088	Forms part of the polypeptide exit tunnel
BTD91_07820	COG0089	rRNA binding
BTD91_07825	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BTD91_07830	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BTD91_07840	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BTD91_07845	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BTD91_07855	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BTD91_07860	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BTD91_07865	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BTD91_07870	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BTD91_07875	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BTD91_07880	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BTD91_07885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BTD91_07895	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BTD91_07900	COG1841	ribosomal large subunit assembly
BTD91_07905	COG0200	Binds to the 23S rRNA
BTD91_07910	COG0201	protein transport
BTD91_07915	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTD91_07920	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BTD91_07925	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BTD91_07930	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BTD91_07935	COG0202	RNA polymerase activity
BTD91_07940	COG0203	ribosomal protein L17
BTD91_07950	COG0545	Peptidyl-prolyl cis-trans isomerase
BTD91_07955	COG3266	domain, Protein
BTD91_07955	COG3061	Opacity-associated protein A
BTD91_07965	COG2153	protein acetylation
BTD91_07995	COG0189	ligase activity
BTD91_07995	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BTD91_08010	COG0175	sulfate reduction
BTD91_08015	COG2895	sulfate adenylyltransferase (ATP) activity
BTD91_08020	COG0471	metal ion transport
BTD91_08020	COG3273	potassium ion transport
BTD91_08025	COG0529	Catalyzes the synthesis of activated sulfate
BTD91_08060	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BTD91_08070	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTD91_08075	COG0729	surface antigen
BTD91_08080	COG2911	Protein conserved in bacteria
BTD91_08085	COG2105	PFAM AIG2 family protein
BTD91_08090	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BTD91_08095	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BTD91_08100	COG0163	prenyltransferase activity
BTD91_08105	COG4143	(ABC) transporter
BTD91_08110	COG1178	ABC-type Fe3 transport system permease component
BTD91_08115	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BTD91_08120	COG3028	Belongs to the UPF0307 family
BTD91_08125	COG0312	modulator of DNA gyrase
BTD91_08130	COG2239	Acts as a magnesium transporter
BTD91_08135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTD91_08140	COG1660	Displays ATPase and GTPase activities
BTD91_08145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTD91_08150	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BTD91_08160	COG1137	ATPase activity
BTD91_08165	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BTD91_08175	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BTD91_08180	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BTD91_08180	COG0517	IMP dehydrogenase activity
BTD91_08190	COG1127	ABC transporter
BTD91_08195	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BTD91_08200	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BTD91_08205	COG2854	intermembrane phospholipid transfer
BTD91_08215	COG5007	Belongs to the BolA IbaG family
BTD91_08220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTD91_08225	COG0204	Acyl-transferase
BTD91_08230	COG0251	oxidation-reduction process
BTD91_08235	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BTD91_08265	COG0456	acetyltransferase
BTD91_08275	COG0525	valine-tRNA ligase activity
BTD91_08280	COG2927	DNA polymerase III (CHI subunit)
BTD91_08285	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BTD91_08290	COG0795	lipopolysaccharide-transporting ATPase activity
BTD91_08295	COG0795	lipopolysaccharide-transporting ATPase activity
BTD91_08410	COG0840	transmembrane signaling receptor activity
BTD91_08450	COG0741	lytic transglycosylase activity
BTD91_08455	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BTD91_08470	COG2066	Belongs to the glutaminase family
BTD91_08475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTD91_08480	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BTD91_08495	COG0762	integral membrane protein
BTD91_08500	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BTD91_08505	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BTD91_08520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BTD91_08525	COG1678	Uncharacterized ACR, COG1678
BTD91_08530	COG0189	ligase activity
BTD91_08535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BTD91_08540	COG2356	endonuclease I
BTD91_08545	COG3091	SprT-like family
BTD91_08555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BTD91_08565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTD91_08570	COG0583	DNA-binding transcription factor activity
BTD91_08575	COG4771	TonB-dependent receptor
BTD91_08590	COG0191	fructose-bisphosphate aldolase activity
BTD91_08595	COG0668	transmembrane transport
BTD91_08605	COG1279	arginine transmembrane transporter activity
BTD91_08620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTD91_08625	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BTD91_08630	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTD91_08640	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BTD91_08645	COG3079	Belongs to the UPF0149 family
BTD91_08650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTD91_08655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTD91_08665	COG0442	prolyl-tRNA aminoacylation
BTD91_08670	COG0354	folic acid binding
BTD91_08675	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BTD91_08680	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BTD91_08685	COG1595	DNA-templated transcription, initiation
BTD91_08705	COG0481	GTPase activity
BTD91_08715	COG0571	ribonuclease III activity
BTD91_08720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BTD91_08725	COG1381	Involved in DNA repair and RecF pathway recombination
BTD91_08730	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BTD91_08735	COG0736	holo-[acyl-carrier-protein] synthase activity
BTD91_08740	COG4999	Histidine kinase
BTD91_08740	COG2205	protein histidine kinase activity
BTD91_08740	COG3850	Histidine kinase
BTD91_08740	COG3437	response regulator, receiver
BTD91_08745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BTD91_08750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTD91_08755	COG3956	TIGRFAM MazG family protein
BTD91_08760	COG0504	CTP synthase activity
BTD91_08765	COG0148	phosphopyruvate hydratase activity
BTD91_08770	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BTD91_08775	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BTD91_08785	COG0585	pseudouridine synthase activity
BTD91_08790	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BTD91_08795	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BTD91_08800	COG4942	peptidase
BTD91_08800	COG1388	LysM domain
BTD91_08805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTD91_08810	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BTD91_08815	COG1546	Belongs to the CinA family
BTD91_08825	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BTD91_08880	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BTD91_08885	COG0732	type I restriction modification DNA specificity domain
BTD91_08895	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BTD91_08920	COG0527	aspartate kinase activity
BTD91_08925	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BTD91_08980	COG3630	sodium ion export across plasma membrane
BTD91_08985	COG5016	pyruvate
BTD91_08985	COG0511	ligase activity, forming carbon-carbon bonds
BTD91_08990	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BTD91_09000	COG1238	metal cluster binding
BTD91_09005	COG0612	Peptidase, M16
BTD91_09020	COG1854	S-ribosylhomocysteine lyase activity
BTD91_09025	COG4536	flavin adenine dinucleotide binding
BTD91_09030	COG4137	Cytochrome C assembly protein
BTD91_09035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTD91_09040	COG0228	four-way junction DNA binding
BTD91_09045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BTD91_09050	COG0336	Belongs to the RNA methyltransferase TrmD family
BTD91_09055	COG0335	large ribosomal subunit rRNA binding
BTD91_09065	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BTD91_09070	COG0237	dephospho-CoA kinase activity
BTD91_09080	COG1459	type II secretion system
BTD91_09085	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BTD91_09095	COG0157	Belongs to the NadC ModD family
BTD91_09110	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BTD91_09115	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTD91_09120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTD91_09135	COG0288	reversible hydration of carbon dioxide
BTD91_09140	COG0659	secondary active sulfate transmembrane transporter activity
BTD91_09145	COG1131	(ABC) transporter
BTD91_09150	COG0842	Transport permease protein
BTD91_09155	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BTD91_09160	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BTD91_09165	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BTD91_09175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTD91_09185	COG1489	DNA binding
BTD91_09190	COG1643	Atp-dependent helicase
BTD91_09195	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BTD91_09200	COG1752	Esterase of the alpha-beta hydrolase superfamily
BTD91_09205	COG1049	propionate catabolic process, 2-methylcitrate cycle
BTD91_09220	COG0004	ammonium transporteR
BTD91_09225	COG1840	ABC-type Fe3 transport system, periplasmic component
BTD91_09235	COG3842	ATPase activity
BTD91_09240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTD91_09255	COG2971	BadF BadG BcrA BcrD
BTD91_09265	COG4608	Belongs to the ABC transporter superfamily
BTD91_09270	COG0444	Belongs to the ABC transporter superfamily
BTD91_09275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTD91_09285	COG0747	negative chemotaxis
BTD91_09295	COG2813	Specifically methylates the guanine in position
BTD91_09300	COG0628	permease
BTD91_09305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BTD91_09310	COG0316	Belongs to the HesB IscA family
BTD91_09325	COG0739	heme binding
BTD91_09330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BTD91_09335	COG2239	Acts as a magnesium transporter
BTD91_09340	COG2027	D-alanyl-D-alanine carboxypeptidase
BTD91_09350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BTD91_09355	COG1534	Rna-binding protein
BTD91_09360	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BTD91_09365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTD91_09370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BTD91_09375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTD91_09380	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTD91_09395	COG0779	Required for maturation of 30S ribosomal subunits
BTD91_09400	COG0195	Participates in both transcription termination and antitermination
BTD91_09405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BTD91_09410	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BTD91_09415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BTD91_09420	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BTD91_09425	COG1185	polyribonucleotide nucleotidyltransferase activity
BTD91_09440	COG0534	Mate efflux family protein
BTD91_09445	COG0826	peptidase U32
BTD91_09450	COG0826	peptidase U32
BTD91_09460	COG3154	lipid carrier protein
BTD91_09465	COG3153	acetyltransferase
BTD91_09480	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BTD91_09490	COG0084	hydrolase, TatD family'
BTD91_09495	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTD91_09500	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BTD91_09505	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BTD91_09515	COG0813	purine-nucleoside phosphorylase activity
BTD91_09525	COG0560	Phosphoserine phosphatase
BTD91_09535	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BTD91_09540	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTD91_09545	COG4628	conserved protein (DUF2132)
BTD91_09550	COG0583	DNA-binding transcription factor activity
BTD91_09560	COG1022	Amp-dependent synthetase and ligase
BTD91_09590	COG4964	Belongs to the GSP D family
BTD91_09650	COG2059	Chromate
BTD91_09655	COG0583	DNA-binding transcription factor activity
BTD91_09660	COG1757	Na H antiporter
BTD91_09665	COG1584	GPR1 FUN34 yaaH family protein
BTD91_09670	COG1115	amino acid carrier protein
BTD91_09695	COG4067	protein conserved in archaea
BTD91_09695	COG0189	ligase activity
BTD91_09735	COG0582	viral genome integration into host DNA
BTD91_09750	COG2867	negative regulation of translational initiation
BTD91_09755	COG2914	Belongs to the UPF0125 (RnfH) family
BTD91_09760	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTD91_09765	COG0497	DNA recombination
BTD91_09770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BTD91_09775	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BTD91_09780	COG1301	dicarboxylic acid transport
BTD91_09785	COG0443	Heat shock 70 kDa protein
BTD91_09790	COG0484	heat shock protein binding
BTD91_09820	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BTD91_09840	COG0047	phosphoribosylformylglycinamidine synthase activity
BTD91_09840	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTD91_09845	COG2171	N-acyltransferase activity
BTD91_09855	COG2095	MarC family integral membrane protein
BTD91_09860	COG3141	response to X-ray
BTD91_09875	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BTD91_09880	COG1074	ATP-dependent DNA helicase activity
BTD91_09885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BTD91_09895	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BTD91_09895	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BTD91_09905	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BTD91_09910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BTD91_09915	COG2166	iron-sulfur cluster assembly
BTD91_09920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTD91_09925	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BTD91_09930	COG3248	Nucleoside-binding outer membrane protein
BTD91_09935	COG2211	Major facilitator Superfamily
BTD91_09940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTD91_09950	COG2813	Specifically methylates the guanine in position
BTD91_09955	COG0271	Belongs to the BolA IbaG family
BTD91_09960	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BTD91_09965	COG1805	sodium ion transport
BTD91_09975	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BTD91_09980	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BTD91_09990	COG1477	protein flavinylation
BTD91_09995	COG2991	Protein conserved in bacteria
BTD91_10000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BTD91_10010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BTD91_10020	COG0733	neurotransmitter:sodium symporter activity
BTD91_10025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BTD91_10030	COG0321	lipoyl(octanoyl) transferase activity
BTD91_10040	COG1686	Belongs to the peptidase S11 family
BTD91_10045	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BTD91_10050	COG0772	Belongs to the SEDS family
BTD91_10055	COG0768	penicillin binding
BTD91_10060	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BTD91_10065	COG0799	negative regulation of ribosome biogenesis
BTD91_10070	COG1466	dna polymerase III delta subunit
BTD91_10075	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
BTD91_10080	COG0495	leucyl-tRNA aminoacylation
BTD91_10085	COG2888	peptidyl-tyrosine sulfation
BTD91_10090	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BTD91_10095	COG4535	Mg2 and Co2 transporter CorC
BTD91_10100	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BTD91_10105	COG1702	phosphate starvation-inducible protein PhoH
BTD91_10115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTD91_10120	COG2706	6-phosphogluconolactonase activity
BTD91_10225	COG0193	aminoacyl-tRNA hydrolase activity
BTD91_10230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BTD91_10235	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BTD91_10240	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BTD91_10245	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BTD91_10250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BTD91_10255	COG2890	protein-(glutamine-N5) methyltransferase activity
BTD91_10265	COG2912	Transglutaminase-like superfamily
BTD91_10270	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BTD91_10280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BTD91_10285	COG1187	pseudouridine synthase activity
BTD91_10290	COG2840	Smr protein MutS2
BTD91_10320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTD91_10325	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BTD91_10335	COG2217	Heavy metal translocating P-type atpase
BTD91_10335	COG2608	mercury ion transmembrane transporter activity
BTD91_10350	COG1028	Short-chain dehydrogenase reductase Sdr
BTD91_10385	COG2986	histidine ammonia-lyase
BTD91_10390	COG1216	Glycosyl transferase, family 2
BTD91_10410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTD91_10415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTD91_10480	COG0784	Response regulator, receiver
BTD91_10480	COG0835	chemotaxis
BTD91_10485	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BTD91_10490	COG1815	bacterial-type flagellum-dependent cell motility
BTD91_10495	COG1558	bacterial-type flagellum-dependent cell motility
BTD91_10510	COG4787	bacterial-type flagellum-dependent cell motility
BTD91_10520	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BTD91_10525	COG1706	bacterial-type flagellum-dependent cell motility
BTD91_10530	COG3951	Flagellar rod assembly protein muramidase FlgJ
BTD91_10530	COG1705	Flagellar rod assembly protein muramidase FlgJ
BTD91_10550	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTD91_10555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BTD91_10565	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BTD91_10575	COG1516	flagellar protein fliS
BTD91_10595	COG1677	Flagellar hook-basal body complex protein FliE
BTD91_10605	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BTD91_10655	COG1987	bacterial-type flagellum assembly
BTD91_10695	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BTD91_10700	COG0643	Histidine kinase
BTD91_10700	COG0784	Response regulator, receiver
BTD91_10700	COG2198	Histidine kinase
BTD91_10705	COG2201	protein-glutamate methylesterase activity
BTD91_10710	COG1192	Involved in chromosome partitioning
BTD91_10720	COG0835	chemotaxis
BTD91_10730	COG4133	protoheme IX ABC transporter activity
BTD91_10735	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTD91_10740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTD91_10750	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BTD91_10755	COG1138	Cytochrome C-type biogenesis protein
BTD91_10760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTD91_10765	COG4235	cytochrome complex assembly
BTD91_10765	COG3088	subunit of a heme lyase
BTD91_10770	COG3088	subunit of a heme lyase
BTD91_10770	COG4235	cytochrome complex assembly
BTD91_10775	COG2853	Lipoprotein
BTD91_10785	COG2067	long-chain fatty acid transport protein
BTD91_10800	COG0183	Belongs to the thiolase family
BTD91_10805	COG1024	Enoyl-CoA hydratase
BTD91_10805	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTD91_10815	COG2062	phosphohistidine phosphatase, SixA
BTD91_10825	COG2890	protein-(glutamine-N5) methyltransferase activity
BTD91_10830	COG1280	lysine exporter protein (LysE YggA)
BTD91_10835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BTD91_10855	COG1175	transmembrane transport
BTD91_10865	COG3842	ATPase activity
BTD91_10870	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTD91_10875	COG2070	2-Nitropropane dioxygenase
BTD91_10875	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BTD91_10890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTD91_10890	COG3321	synthase
BTD91_10905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTD91_10910	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTD91_10915	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTD91_10935	COG0544	peptidyl-prolyl cis-trans isomerase activity
BTD91_10940	COG0740	serine-type endopeptidase activity
BTD91_10945	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BTD91_10950	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BTD91_10955	COG0776	regulation of translation
BTD91_10960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTD91_10965	COG1555	photosystem II stabilization
BTD91_10980	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BTD91_10985	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BTD91_10990	COG0436	Aminotransferase
BTD91_11000	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BTD91_11005	COG2267	carboxylic ester hydrolase activity
BTD91_11030	COG2855	membrane
BTD91_11085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTD91_11095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTD91_11100	COG2084	Dehydrogenase
BTD91_11110	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BTD91_11115	COG1522	sequence-specific DNA binding
BTD91_11125	COG1946	Acyl-CoA thioesterase
BTD91_11130	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BTD91_11150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTD91_11170	COG3341	Caulimovirus viroplasmin
BTD91_11170	COG0328	RNA-DNA hybrid ribonuclease activity
BTD91_11175	COG1216	Glycosyl transferase, family 2
BTD91_11175	COG0463	Glycosyl transferase, family 2
BTD91_11185	COG1214	PFAM Peptidase M22, glycoprotease
BTD91_11185	COG0456	acetyltransferase
BTD91_11195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BTD91_11220	COG0069	glutamate synthase activity
BTD91_11250	COG1522	sequence-specific DNA binding
BTD91_11255	COG1280	lysine exporter protein (LysE YggA)
BTD91_11275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BTD91_11295	COG3040	lipid binding
BTD91_11300	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BTD91_11305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTD91_11310	COG1845	cytochrome c oxidase, subunit III
BTD91_11315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BTD91_11330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTD91_11345	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BTD91_11345	COG0617	tRNA 3'-terminal CCA addition
BTD91_11345	COG0517	IMP dehydrogenase activity
BTD91_11355	COG2217	Heavy metal translocating P-type atpase
BTD91_11375	COG0537	adenosine 5'-monophosphoramidase activity
BTD91_11400	COG3150	esterase
BTD91_11405	COG1252	NADH dehydrogenase
BTD91_11420	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTD91_11430	COG4591	ABC-type transport system involved in lipoprotein release permease component
BTD91_11435	COG1136	(ABC) transporter
BTD91_11440	COG4591	ABC-type transport system involved in lipoprotein release permease component
BTD91_11450	COG2333	competence protein COMEC
BTD91_11450	COG0658	competence protein
BTD91_11455	COG1132	(ABC) transporter
BTD91_11460	COG1663	tetraacyldisaccharide 4'-kinase activity
BTD91_11465	COG2835	tetraacyldisaccharide 4'-kinase activity
BTD91_11470	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BTD91_11475	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BTD91_11480	COG0539	negative regulation of cytoplasmic translation
BTD91_11485	COG0776	regulation of translation
BTD91_11490	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BTD91_11495	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BTD91_11500	COG0284	orotidine-5'-phosphate decarboxylase activity
BTD91_11515	COG0583	DNA-binding transcription factor activity
BTD91_11525	COG0686	Belongs to the AlaDH PNT family
BTD91_11530	COG1522	sequence-specific DNA binding
BTD91_11540	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BTD91_11545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTD91_11550	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BTD91_11555	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTD91_11560	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BTD91_11565	COG0156	8-amino-7-oxononanoate synthase activity
BTD91_11575	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BTD91_11585	COG0501	Belongs to the peptidase M48B family
BTD91_11590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTD91_11595	COG2915	High frequency lysogenization protein hflD homolog
BTD91_11600	COG0482	sulfurtransferase activity
BTD91_11610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTD91_11615	COG2916	Histone family protein nucleoid-structuring protein H-NS
BTD91_11620	COG1757	Na H antiporter
BTD91_11635	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BTD91_11640	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BTD91_11640	COG0131	Imidazoleglycerol-phosphate dehydratase
BTD91_11645	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BTD91_11650	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BTD91_11655	COG0107	imidazoleglycerol-phosphate synthase activity
BTD91_11660	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BTD91_11660	COG0140	phosphoribosyl-ATP diphosphatase activity
BTD91_11665	COG3012	SEC-C Motif Domain Protein
BTD91_11670	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BTD91_11675	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTD91_11680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BTD91_11685	COG0215	cysteine-tRNA ligase activity
BTD91_11695	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BTD91_11715	COG0390	transport system, permease component
BTD91_11720	COG4459	periplasmic nitrate reductase
BTD91_11725	COG3005	denitrification pathway
BTD91_11730	COG0243	molybdopterin cofactor binding
BTD91_11740	COG1227	inorganic diphosphatase activity
BTD91_11755	COG4172	Belongs to the ABC transporter superfamily
BTD91_11770	COG4168	peptide transport system, permease
BTD91_11775	COG4166	transmembrane transport
BTD91_11780	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BTD91_11795	COG1983	PspC domain protein
BTD91_11815	COG2818	Glycosylase
BTD91_11820	COG0626	cystathionine gamma-synthase activity
BTD91_11830	COG0733	neurotransmitter:sodium symporter activity
BTD91_11835	COG0564	pseudouridine synthase activity
BTD91_11840	COG0116	Belongs to the methyltransferase superfamily
BTD91_11840	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BTD91_11845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTD91_11850	COG4136	ATPase activity
BTD91_11855	COG4135	transport system, permease component
BTD91_11860	COG4134	Bacterial extracellular solute-binding protein
BTD91_11870	COG3313	Fe-S protein
BTD91_11890	COG0513	Belongs to the DEAD box helicase family
BTD91_11900	COG2866	Carboxypeptidase
BTD91_11920	COG4176	ABC-type proline glycine betaine transport system permease component
BTD91_11925	COG2113	Glycine betaine
BTD91_11935	COG3437	response regulator, receiver
BTD91_12010	COG0745	RESPONSE REGULATOR receiver
BTD91_12245	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BTD91_12250	COG0642	Histidine kinase
BTD91_12265	COG1061	Type III restriction enzyme res subunit
BTD91_12275	COG2814	Major facilitator Superfamily
BTD91_12285	COG0702	epimerase
BTD91_12290	COG0534	Mate efflux family protein
BTD91_12295	COG1136	(ABC) transporter
BTD91_12315	COG3047	cAMP biosynthetic process
BTD91_12315	COG2885	chlorophyll binding
BTD91_12340	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BTD91_12345	COG3273	potassium ion transport
BTD91_12345	COG2985	domain, Protein
BTD91_12350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTD91_12355	COG1737	Transcriptional regulator
BTD91_12360	COG0076	glutamate decarboxylase activity
BTD91_12370	COG2431	L-lysine efflux transmembrane transporter activity
BTD91_12380	COG3070	regulator of competence-specific genes
BTD91_12395	COG4191	Histidine kinase
BTD91_12405	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BTD91_12420	COG2258	MOSC domain
BTD91_12440	COG1448	Aminotransferase
BTD91_12445	COG2770	Histidine kinase
BTD91_12445	COG3437	response regulator, receiver
BTD91_12455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTD91_12465	COG0017	Asparaginyl-tRNA synthetase
BTD91_12470	COG0840	transmembrane signaling receptor activity
BTD91_12475	COG0720	synthase
BTD91_12485	COG0583	DNA-binding transcription factor activity
BTD91_12490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTD91_12495	COG0814	amino acid
BTD91_12500	COG1760	l-serine dehydratase
BTD91_12505	COG0814	amino acid
BTD91_12510	COG0494	nUDIX hydrolase
BTD91_12520	COG0784	Response regulator, receiver
BTD91_12520	COG5002	protein histidine kinase activity
BTD91_12525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BTD91_12540	COG3106	COG3106 Predicted ATPase
BTD91_12555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTD91_12565	COG5001	Diguanylate cyclase
BTD91_12575	COG0443	Heat shock 70 kDa protein
BTD91_12590	COG3706	GGDEF domain
BTD91_12620	COG1643	Atp-dependent helicase
BTD91_12665	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BTD91_12670	COG0072	phenylalanine-tRNA ligase activity
BTD91_12670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTD91_12705	COG2207	Transcriptional regulator
BTD91_12710	COG1522	sequence-specific DNA binding
BTD91_12715	COG2873	o-acetylhomoserine
BTD91_12725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BTD91_12730	COG0583	DNA-binding transcription factor activity
BTD91_12740	COG0730	response to heat
BTD91_12760	COG1342	Belongs to the UPF0251 family
BTD91_12785	COG0776	regulation of translation
BTD91_12830	COG2378	regulation of single-species biofilm formation
BTD91_12850	COG0583	DNA-binding transcription factor activity
BTD91_12870	COG0776	regulation of translation
BTD91_12880	COG0500	methyltransferase
BTD91_12885	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BTD91_12890	COG0295	cytidine deaminase activity
BTD91_12895	COG1346	cytolysis
BTD91_12905	COG2925	Exonuclease
BTD91_12930	COG3568	Endonuclease Exonuclease Phosphatase
BTD91_12935	COG3122	Protein conserved in bacteria
BTD91_12940	COG1823	symporter activity
BTD91_12945	COG0702	epimerase
BTD91_12950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTD91_12955	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BTD91_12960	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BTD91_12980	COG2988	succinylglutamate desuccinylase activity
BTD91_12985	COG4139	cobalamin transport
BTD91_12990	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BTD91_13000	COG1028	Short-chain dehydrogenase reductase Sdr
BTD91_13000	COG0604	alcohol dehydrogenase
BTD91_13000	COG3321	synthase
BTD91_13020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTD91_13025	COG1271	oxidase subunit
BTD91_13030	COG1294	oxidase, subunit
BTD91_13040	COG1247	-acetyltransferase
BTD91_13060	COG2814	Major facilitator Superfamily
BTD91_13065	COG0583	DNA-binding transcription factor activity
BTD91_13075	COG1451	nucleotide metabolic process
BTD91_13085	COG3063	Type IV pilus biogenesis stability protein PilW
BTD91_13090	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BTD91_13105	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTD91_13130	COG0583	DNA-binding transcription factor activity
BTD91_13150	COG4964	Belongs to the GSP D family
BTD91_13160	COG0455	bacterial-type flagellum organization
BTD91_13210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BTD91_13215	COG0583	DNA-binding transcription factor activity
BTD91_13220	COG0840	transmembrane signaling receptor activity
BTD91_13235	COG0454	-acetyltransferase
BTD91_13245	COG0420	3'-5' exonuclease activity
BTD91_13250	COG0419	ATPase involved in DNA repair
BTD91_13265	COG3046	protein related to deoxyribodipyrimidine photolyase
BTD91_13270	COG0589	response to stress
BTD91_13300	COG0494	nUDIX hydrolase
BTD91_13315	COG1187	pseudouridine synthase activity
BTD91_13335	COG1051	belongs to the nudix hydrolase family
BTD91_13375	COG0346	lactoylglutathione lyase activity
BTD91_13395	COG0653	protein targeting
BTD91_13400	COG1028	Short-chain dehydrogenase reductase Sdr
BTD91_13425	COG0826	peptidase U32
BTD91_13440	COG1126	abc transporter atp-binding protein
BTD91_13445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTD91_13450	COG4215	(ABC) transporter
BTD91_13455	COG4160	amino acid transport
BTD91_13525	COG4122	O-methyltransferase activity
BTD91_13565	COG1278	Cold shock
BTD91_13585	COG0242	peptide deformylase activity
BTD91_13680	COG0242	peptide deformylase activity
BTD91_13695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BTD91_13700	COG1215	transferase activity, transferring glycosyl groups
BTD91_13735	COG2204	response regulator
BTD91_13755	COG2885	chlorophyll binding
BTD91_13765	COG1793	dna ligase
BTD91_13770	COG0534	Mate efflux family protein
BTD91_13775	COG0307	riboflavin synthase, alpha
BTD91_13795	COG0791	NLP P60 protein
BTD91_13800	COG0840	transmembrane signaling receptor activity
BTD91_13810	COG3148	PFAM DTW domain containing protein
BTD91_13815	COG1940	carbohydrate kinase activity
BTD91_13825	COG0303	'Molybdopterin
BTD91_13830	COG0746	molybdenum cofactor guanylyltransferase activity
BTD91_13835	COG3842	ATPase activity
BTD91_13840	COG4662	Binding-protein-dependent transport system inner membrane component
BTD91_13855	COG4191	Histidine kinase
BTD91_13860	COG0840	transmembrane signaling receptor activity
BTD91_13875	COG0488	(ABC) transporter
BTD91_13880	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BTD91_13900	COG3381	protein complex oligomerization
BTD91_13910	COG0243	molybdopterin cofactor binding
BTD91_13910	COG3383	formate dehydrogenase (NAD+) activity
BTD91_13915	COG0437	4 iron, 4 sulfur cluster binding
BTD91_13930	COG0004	ammonium transporteR
BTD91_13935	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BTD91_13940	COG3706	GGDEF domain
BTD91_13945	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BTD91_13950	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BTD91_13955	COG1177	transmembrane transport
BTD91_13965	COG3842	ATPase activity
BTD91_13985	COG0037	tRNA processing
BTD91_13990	COG0589	response to stress
BTD91_13995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BTD91_14010	COG2217	Heavy metal translocating P-type atpase
BTD91_14020	COG2010	Cytochrome c
BTD91_14035	COG3278	Belongs to the heme-copper respiratory oxidase family
BTD91_14050	COG2205	protein histidine kinase activity
BTD91_14050	COG0784	Response regulator, receiver
BTD91_14085	COG3120	sequence-specific DNA binding
BTD91_14090	COG1067	ATP-dependent peptidase activity
BTD91_14110	COG0488	(ABC) transporter
BTD91_14120	COG0116	Belongs to the methyltransferase superfamily
BTD91_14120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BTD91_14130	COG0167	dihydroorotate dehydrogenase activity
BTD91_14135	COG2902	Dehydrogenase
BTD91_14145	COG0308	aminopeptidase N
BTD91_14160	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BTD91_14165	COG1956	GAF domain-containing protein
BTD91_14170	COG1132	(ABC) transporter
BTD91_14175	COG2995	paraquat-inducible protein a
BTD91_14180	COG3008	intermembrane lipid transfer
BTD91_14185	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BTD91_14185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTD91_14190	COG2996	Protein conserved in bacteria
BTD91_14205	COG0574	Belongs to the PEP-utilizing enzyme family
BTD91_14205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BTD91_14210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTD91_14215	COG1666	GTP binding
BTD91_14225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTD91_14230	COG4597	amino acid ABC transporter
BTD91_14235	COG0765	amino acid transport
BTD91_14240	COG1126	abc transporter atp-binding protein
BTD91_14245	COG0670	Belongs to the BI1 family
BTD91_14250	COG2920	part of a sulfur-relay system
BTD91_14255	COG1254	Belongs to the acylphosphatase family
BTD91_14265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BTD91_14335	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BTD91_14375	COG1881	PFAM PEBP family protein
BTD91_14385	COG0745	RESPONSE REGULATOR receiver
BTD91_14425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTD91_14450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTD91_14460	COG1538	Outer membrane efflux protein
BTD91_14465	COG1132	(ABC) transporter
BTD91_14480	COG5002	protein histidine kinase activity
BTD91_14480	COG0784	Response regulator, receiver
BTD91_14480	COG2205	protein histidine kinase activity
BTD91_14490	COG0641	radical SAM
BTD91_14500	COG1597	lipid kinase activity
BTD91_14535	COG0714	Associated with various cellular activities
BTD91_14545	COG3119	arylsulfatase activity
BTD91_14550	COG3119	arylsulfatase activity
BTD91_14565	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BTD91_14570	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BTD91_14575	COG0456	acetyltransferase
BTD91_14580	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BTD91_14585	COG0454	-acetyltransferase
BTD91_14595	COG0384	phenazine biosynthesis protein PhzF
BTD91_14625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTD91_14635	COG1012	belongs to the aldehyde dehydrogenase family
BTD91_14655	COG4172	Belongs to the ABC transporter superfamily
BTD91_14660	COG4239	(ABC) transporter, permease
BTD91_14665	COG4174	ABC transporter (Permease)
BTD91_14670	COG4166	transmembrane transport
BTD91_14685	COG1869	D-ribose catabolic process
BTD91_14690	COG1129	ABC transporter
BTD91_14695	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTD91_14700	COG1879	ABC-type sugar transport system periplasmic component
BTD91_14705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTD91_14710	COG1609	Transcriptional regulator
BTD91_14755	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTD91_14755	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTD91_14765	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTD91_14775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BTD91_14780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BTD91_14785	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BTD91_14790	COG0583	DNA-binding transcription factor activity
BTD91_14795	COG0243	molybdopterin cofactor binding
BTD91_14800	COG2146	nitrite reductase [NAD(P)H] activity
BTD91_14800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BTD91_14810	COG2223	nitrite transmembrane transporter activity
BTD91_14815	COG2815	serine threonine protein kinase
BTD91_14815	COG0515	serine threonine protein kinase
BTD91_14820	COG1609	Transcriptional regulator
BTD91_14825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTD91_14825	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTD91_14830	COG1105	Belongs to the carbohydrate kinase PfkB family
BTD91_14835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTD91_14835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BTD91_14835	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BTD91_14845	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTD91_14860	COG0625	glutathione transferase activity
BTD91_14885	COG2198	Histidine kinase
BTD91_14885	COG0784	Response regulator, receiver
BTD91_14885	COG2205	protein histidine kinase activity
BTD91_14890	COG1879	ABC-type sugar transport system periplasmic component
BTD91_14895	COG1803	Methylglyoxal synthase
BTD91_14905	COG0210	DNA helicase
BTD91_14910	COG1289	transmembrane transporter activity
BTD91_14930	COG0583	DNA-binding transcription factor activity
BTD91_14935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BTD91_14940	COG1328	CTP reductase activity
BTD91_14945	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTD91_14970	COG1011	Hydrolase
BTD91_14980	COG1454	alcohol dehydrogenase
BTD91_14990	COG1063	alcohol dehydrogenase
BTD91_14995	COG0156	8-amino-7-oxononanoate synthase activity
BTD91_15005	COG0583	DNA-binding transcription factor activity
BTD91_15030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTD91_15035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BTD91_15050	COG0393	Putative heavy-metal-binding
BTD91_15070	COG1132	(ABC) transporter
BTD91_15075	COG1132	(ABC) transporter
BTD91_15170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BTD91_15220	COG4695	Portal protein
BTD91_15330	COG4974	Belongs to the 'phage' integrase family
BTD91_15355	COG1760	l-serine dehydratase
BTD91_15360	COG2375	cellular response to nickel ion
BTD91_15365	COG1609	Transcriptional regulator
BTD91_15370	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BTD91_15375	COG3265	gluconokinase activity
BTD91_15380	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTD91_15390	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BTD91_15410	COG3842	ATPase activity
BTD91_15420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTD91_15425	COG1840	ABC-type Fe3 transport system, periplasmic component
BTD91_15435	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTD91_15445	COG2885	chlorophyll binding
BTD91_15450	COG1765	OsmC-like protein
BTD91_15455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTD91_15455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BTD91_15460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTD91_15465	COG0569	domain protein
BTD91_15470	COG0668	transmembrane transport
BTD91_15480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTD91_15485	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BTD91_15490	COG3530	Putative quorum-sensing-regulated virulence factor
BTD91_15500	COG0109	protoheme IX farnesyltransferase activity
BTD91_15505	COG1612	heme a metabolic process
BTD91_15525	COG1845	cytochrome c oxidase, subunit III
BTD91_15545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTD91_15550	COG1280	lysine exporter protein (LysE YggA)
BTD91_15555	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTD91_15565	COG0443	Heat shock 70 kDa protein
BTD91_15595	COG2827	Endonuclease containing a URI domain
BTD91_15600	COG3132	Protein of unknown function, DUF480
BTD91_15610	COG2926	Belongs to the UPF0265 family
BTD91_15615	COG5002	protein histidine kinase activity
BTD91_15615	COG2205	protein histidine kinase activity
BTD91_15615	COG0784	Response regulator, receiver
BTD91_15625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTD91_15630	COG1151	hydroxylamine reductase activity
BTD91_15645	COG1280	lysine exporter protein (LysE YggA)
BTD91_15655	COG0531	amino acid
BTD91_15675	COG1278	Cold shock
BTD91_15680	COG3706	GGDEF domain
BTD91_15695	COG0513	Belongs to the DEAD box helicase family
BTD91_15720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BTD91_15740	COG3037	sugar-specific permease SgaT UlaA
BTD91_15750	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BTD91_15755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTD91_15770	COG1131	(ABC) transporter
BTD91_15815	COG4964	Belongs to the GSP D family
BTD91_15870	COG0564	pseudouridine synthase activity
BTD91_15900	COG4264	IucA IucC family
BTD91_15910	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTD91_15915	COG1120	ATPase activity
BTD91_15940	COG0189	ligase activity
BTD91_15945	COG4067	protein conserved in archaea
BTD91_15945	COG0189	ligase activity
BTD91_15975	COG0395	ABC-type sugar transport system, permease component
BTD91_15980	COG3842	ATPase activity
BTD91_15985	COG0584	glycerophosphoryl diester phosphodiesterase
BTD91_16000	COG0673	inositol 2-dehydrogenase activity
BTD91_16010	COG2999	glutathione oxidoreductase activity
BTD91_16015	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BTD91_16025	COG0534	Mate efflux family protein
BTD91_16035	COG2194	sulfuric ester hydrolase activity
BTD91_16085	COG1901	pseudouridine methyltransferase
BTD91_16090	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BTD91_16110	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTD91_16120	COG0583	DNA-binding transcription factor activity
BTD91_16125	COG2910	NAD(P)H-binding
BTD91_16135	COG0583	DNA-binding transcription factor activity
BTD91_16140	COG4221	oxidoreductase activity
BTD91_16155	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BTD91_16160	COG1022	Amp-dependent synthetase and ligase
BTD91_16170	COG3047	cAMP biosynthetic process
BTD91_16175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BTD91_16195	COG3639	organic phosphonate transmembrane transporter activity
BTD91_16200	COG3639	organic phosphonate transmembrane transporter activity
BTD91_16205	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BTD91_16230	COG4948	Mandelate Racemase Muconate Lactonizing
BTD91_16240	COG0583	DNA-binding transcription factor activity
BTD91_16255	COG0583	DNA-binding transcription factor activity
BTD91_16265	COG0697	spore germination
BTD91_16270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTD91_16275	COG0840	transmembrane signaling receptor activity
BTD91_16300	COG4166	transmembrane transport
BTD91_16315	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BTD91_16330	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BTD91_16335	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BTD91_16350	COG1012	belongs to the aldehyde dehydrogenase family
BTD91_16355	COG3284	Transcriptional regulator
BTD91_16370	COG3655	Transcriptional regulator
BTD91_16385	COG1621	beta-fructofuranosidase activity
BTD91_16390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTD91_16395	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTD91_16395	COG1263	PTS System
BTD91_16430	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BTD91_16435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTD91_16440	COG1418	mRNA catabolic process
BTD91_16460	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BTD91_16470	COG0402	S-adenosylhomocysteine deaminase activity
BTD91_16480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTD91_16485	COG0789	Transcriptional regulator
BTD91_16500	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
BTD91_16505	COG4266	Belongs to the allantoicase family
BTD91_16525	COG2252	PERMEase
BTD91_16540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTD91_16545	COG1012	belongs to the aldehyde dehydrogenase family
BTD91_16550	COG2957	Belongs to the agmatine deiminase family
BTD91_16560	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTD91_16565	COG1012	belongs to the aldehyde dehydrogenase family
BTD91_16570	COG1917	Cupin 2, conserved barrel domain protein
BTD91_16570	COG1396	sequence-specific DNA binding
BTD91_16575	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BTD91_16580	COG0174	glutamine synthetase
BTD91_16585	COG1757	Na H antiporter
BTD91_16600	COG2084	Dehydrogenase
BTD91_16605	COG3622	Belongs to the hyi family
BTD91_16610	COG3960	tartronate-semialdehyde synthase activity
BTD91_16615	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BTD91_16625	COG2259	Doxx family
BTD91_16630	COG1846	Transcriptional regulator
BTD91_16660	COG1067	ATP-dependent peptidase activity
BTD91_16670	COG4172	Belongs to the ABC transporter superfamily
BTD91_16680	COG1505	serine-type exopeptidase activity
BTD91_16685	COG0583	DNA-binding transcription factor activity
BTD91_16690	COG1620	l-lactate permease
BTD91_16695	COG1304	FMN binding
BTD91_16715	COG0747	negative chemotaxis
BTD91_16720	COG4172	Belongs to the ABC transporter superfamily
BTD91_16730	COG0534	Mate efflux family protein
BTD91_16735	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BTD91_16735	COG2207	Transcriptional regulator
BTD91_16740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BTD91_16755	COG1054	Belongs to the UPF0176 family
BTD91_16785	COG1741	Belongs to the pirin family
BTD91_16790	COG3123	guanosine phosphorylase activity
BTD91_16805	COG0596	Alpha beta hydrolase
BTD91_16835	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BTD91_16840	COG0700	Nucleoside recognition
BTD91_16845	COG3366	ferrous iron transmembrane transporter activity
BTD91_16850	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BTD91_16860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BTD91_16865	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BTD91_16885	COG0363	glucosamine-6-phosphate deaminase activity
BTD91_16890	COG3722	fumarate hydratase activity
BTD91_16895	COG0246	Mannitol dehydrogenase
BTD91_16900	COG2213	PTS system mannitol-specific
BTD91_16900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTD91_16925	COG0786	glutamate:sodium symporter activity
BTD91_16935	COG1942	4-Oxalocrotonate Tautomerase
BTD91_16945	COG1595	DNA-templated transcription, initiation
BTD91_16950	COG3806	Anti-sigma factor
BTD91_16960	COG0415	Belongs to the DNA photolyase family
BTD91_16985	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BTD91_17010	COG0724	RNA recognition motif
BTD91_17035	COG1028	Short-chain dehydrogenase reductase Sdr
BTD91_17040	COG2814	Major facilitator Superfamily
BTD91_17045	COG1902	pentaerythritol trinitrate reductase activity
BTD91_17060	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTD91_17065	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BTD91_17075	COG0612	Peptidase, M16
BTD91_17080	COG3279	Response regulator of the LytR AlgR family
BTD91_17085	COG3275	phosphorelay sensor kinase activity
BTD91_17100	COG4591	ABC-type transport system involved in lipoprotein release permease component
BTD91_17120	COG0625	glutathione transferase activity
BTD91_17130	COG0583	DNA-binding transcription factor activity
BTD91_17135	COG2084	Dehydrogenase
BTD91_17145	COG0217	transcriptional regulatory protein
BTD91_17160	COG3186	Phenylalanine-4-hydroxylase
BTD91_17165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTD91_17170	COG2814	Major facilitator Superfamily
BTD91_17180	COG0583	DNA-binding transcription factor activity
BTD91_17185	COG3394	polysaccharide catabolic process
BTD91_17190	COG3217	Mosc domain protein beta barrel domain protein
BTD91_17190	COG0633	Ferredoxin
BTD91_17200	COG1028	Short-chain dehydrogenase reductase Sdr
BTD91_17205	COG0861	Integral membrane protein TerC family
BTD91_17210	COG0625	glutathione transferase activity
BTD91_17220	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BTD91_17235	COG3842	ATPase activity
BTD91_17275	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTD91_17275	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
BTD91_17285	COG0444	Belongs to the ABC transporter superfamily
BTD91_17290	COG4608	Belongs to the ABC transporter superfamily
BTD91_17315	COG1444	tRNA N-acetyltransferase activity
BTD91_17355	COG0259	pyridoxamine-phosphate oxidase activity
BTD91_17385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BTD91_17395	COG4399	Belongs to the UPF0754 family
BTD91_17400	COG1132	(ABC) transporter
BTD91_17440	COG1566	PFAM secretion protein HlyD family protein
BTD91_17465	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BTD91_17475	COG4145	pantothenate transmembrane transporter activity
BTD91_17480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTD91_17485	COG0800	Aldolase
BTD91_17500	COG3940	Belongs to the glycosyl hydrolase 43 family
BTD91_17505	COG2017	converts alpha-aldose to the beta-anomer
BTD91_17515	COG2204	response regulator
BTD91_17530	COG0579	oxidoreductase
BTD91_17550	COG2205	protein histidine kinase activity
BTD91_17555	COG0745	RESPONSE REGULATOR receiver
BTD91_17560	COG1309	transcriptional regulator
BTD91_17565	COG1012	belongs to the aldehyde dehydrogenase family
BTD91_17585	COG4175	Glycine betaine
BTD91_17585	COG0517	IMP dehydrogenase activity
BTD91_17590	COG1846	Transcriptional regulator
BTD91_17600	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTD91_17605	COG2213	PTS system mannitol-specific
BTD91_17610	COG1063	alcohol dehydrogenase
BTD91_17620	COG1072	(Pantothenic acid kinase))
BTD91_17625	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BTD91_17640	COG0456	acetyltransferase
BTD91_17645	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BTD91_17650	COG0662	Cupin 2, conserved barrel domain protein
BTD91_17655	COG0527	aspartate kinase activity
BTD91_17680	COG1597	lipid kinase activity
BTD91_17680	COG1803	Methylglyoxal synthase
BTD91_17705	COG0628	permease
BTD91_17710	COG0110	maltose O-acetyltransferase activity
BTD91_17715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BTD91_17725	COG2207	Transcriptional regulator
BTD91_17730	COG2814	Major facilitator Superfamily
BTD91_17740	COG1028	Short-chain dehydrogenase reductase Sdr
BTD91_17740	COG0604	alcohol dehydrogenase
BTD91_17740	COG3321	synthase
BTD91_17765	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BTD91_17765	COG0646	methionine synthase
BTD91_17770	COG2723	6-phospho-beta-galactosidase activity
BTD91_17775	COG1609	Transcriptional regulator
BTD91_17780	COG0110	maltose O-acetyltransferase activity
BTD91_17785	COG2814	Major facilitator Superfamily
BTD91_17790	COG0583	DNA-binding transcription factor activity
BTD91_17795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTD91_17810	COG1794	racemase activity, acting on amino acids and derivatives
BTD91_17830	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BTD91_17835	COG1349	DNA-binding transcription factor activity
BTD91_17840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BTD91_17845	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BTD91_17855	COG0583	DNA-binding transcription factor activity
BTD91_17860	COG0798	PFAM Bile acid sodium symporter
BTD91_17875	COG1309	transcriptional regulator
BTD91_17880	COG0561	phosphatase activity
BTD91_17900	COG1349	DNA-binding transcription factor activity
BTD91_17905	COG2084	Dehydrogenase
BTD91_17910	COG3395	kinase activity
BTD91_17915	COG0235	Class ii aldolase
BTD91_17920	COG3622	Belongs to the hyi family
BTD91_17925	COG2610	gluconate transmembrane transporter activity
BTD91_17930	COG1929	Belongs to the glycerate kinase type-1 family
BTD91_17935	COG0753	catalase activity
BTD91_17940	COG4667	esterase of the alpha-beta hydrolase superfamily
BTD91_17945	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BTD91_17950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTD91_17955	COG0204	Acyl-transferase
BTD91_17975	COG4580	involved in the transport of maltose and maltodextrins
BTD91_18005	COG0583	DNA-binding transcription factor activity
BTD91_18010	COG3258	Cytochrome c
BTD91_18050	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BTD91_18060	COG1999	signal sequence binding
BTD91_18075	COG2909	trisaccharide binding
BTD91_18080	COG0058	SHG alpha-glucan phosphorylase activity
BTD91_18085	COG1640	4-alpha-glucanotransferase
BTD91_18090	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BTD91_18105	COG1122	ATPase activity
BTD91_18110	COG4720	Psort location CytoplasmicMembrane, score
BTD91_18115	COG1566	PFAM secretion protein HlyD family protein
BTD91_18130	COG3706	GGDEF domain
BTD91_18145	COG0813	purine-nucleoside phosphorylase activity
BTD91_18150	COG1376	ErfK ybiS ycfS ynhG family protein
BTD91_18150	COG1388	LysM domain
BTD91_18160	COG0513	Belongs to the DEAD box helicase family
BTD91_18165	COG3240	lipase activity
BTD91_18170	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BTD91_18180	COG1770	oligopeptidase
BTD91_18205	COG0840	transmembrane signaling receptor activity
BTD91_18215	COG0573	inorganic phosphate transmembrane transporter activity
BTD91_18220	COG0581	inorganic phosphate transmembrane transporter activity
BTD91_18225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BTD91_18240	COG2304	oxidoreductase activity
BTD91_18245	COG2304	oxidoreductase activity
BTD91_18260	COG0714	Associated with various cellular activities
BTD91_18265	COG0840	transmembrane signaling receptor activity
BTD91_18275	COG3842	ATPase activity
BTD91_18285	COG1175	transmembrane transport
BTD91_18290	COG3833	ABC-type maltose transport systems, permease component
BTD91_18320	COG5002	protein histidine kinase activity
BTD91_18320	COG3447	MASE1 domain protein
BTD91_18320	COG5001	Diguanylate cyclase
BTD91_18335	COG4934	collagen metabolic process
BTD91_18365	COG1012	belongs to the aldehyde dehydrogenase family
BTD91_18370	COG1414	Transcriptional regulator
BTD91_18380	COG0730	response to heat
BTD91_18410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTD91_18415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BTD91_18420	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTD91_18425	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BTD91_18425	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BTD91_18440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTD91_18450	COG0418	dihydroorotase activity
BTD91_18460	COG3217	Mosc domain protein beta barrel domain protein
BTD91_18460	COG0633	Ferredoxin
BTD91_18465	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BTD91_18510	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BTD91_18515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTD91_18525	COG0848	biopolymer transport protein
BTD91_18530	COG0811	peptide transport
BTD91_18535	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BTD91_18540	COG3721	Heme iron utilization protein
BTD91_18545	COG0748	coenzyme F420 binding
BTD91_18550	COG2096	Adenosyltransferase
BTD91_18555	COG0835	chemotaxis
BTD91_18555	COG0784	Response regulator, receiver
BTD91_18560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTD91_18565	COG0366	Alpha amylase catalytic
BTD91_18575	COG3314	Sporulation integral membrane protein YlbJ
BTD91_18600	COG0739	heme binding
BTD91_18605	COG5001	Diguanylate cyclase
BTD91_18610	COG0583	DNA-binding transcription factor activity
BTD91_18615	COG2814	Major facilitator Superfamily
BTD91_18630	COG0697	spore germination
BTD91_18635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BTD91_18650	COG3118	belongs to the thioredoxin family
BTD91_18655	COG4232	protein-disulfide reductase activity
BTD91_18665	COG0668	transmembrane transport
BTD91_18675	COG0840	transmembrane signaling receptor activity
BTD91_18690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTD91_18695	COG1538	Outer membrane efflux protein
BTD91_18715	COG4989	oxidoreductase activity
BTD91_18720	COG0513	Belongs to the DEAD box helicase family
BTD91_18735	COG2176	DNA-directed DNA polymerase activity
BTD91_18745	COG0513	Belongs to the DEAD box helicase family
BTD91_18750	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BTD91_18755	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BTD91_18760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTD91_18765	COG0667	Aldo Keto reductase
BTD91_18775	COG2195	Cleaves the N-terminal amino acid of tripeptides
BTD91_18810	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BTD91_18825	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BTD91_18830	COG0513	Belongs to the DEAD box helicase family
BTD91_18835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BTD91_18850	COG3655	Transcriptional regulator
BTD91_18855	COG1464	Belongs to the NlpA lipoprotein family
BTD91_18860	COG0800	Aldolase
BTD91_18870	COG1172	Belongs to the binding-protein-dependent transport system permease family
BTD91_18875	COG1129	ABC transporter
BTD91_18880	COG1879	ABC-type sugar transport system periplasmic component
BTD91_18885	COG1069	ribulokinase activity
BTD91_18895	COG2160	L-arabinose isomerase activity
BTD91_18910	COG0561	phosphatase activity
BTD91_18920	COG0583	DNA-binding transcription factor activity
BTD91_18945	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BTD91_18965	COG1335	isochorismatase
BTD91_18985	COG4974	Belongs to the 'phage' integrase family
BTD91_19000	COG2801	Transposase and inactivated derivatives
BTD91_19030	COG1120	ATPase activity
BTD91_19035	COG4774	siderophore transport
BTD91_19040	COG1132	(ABC) transporter
BTD91_19055	COG0366	Alpha amylase catalytic
BTD91_19060	COG0583	DNA-binding transcription factor activity
BTD91_19065	COG0534	Mate efflux family protein
BTD91_19085	COG0516	GMP reductase activity
BTD91_19130	COG0697	spore germination
BTD91_19135	COG0351	phosphomethylpyrimidine kinase
BTD91_19140	COG1116	anion transmembrane transporter activity
BTD91_19145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BTD91_19150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BTD91_19155	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BTD91_19160	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BTD91_19175	COG0583	DNA-binding transcription factor activity
BTD91_19195	COG4607	ABC-type enterochelin transport system periplasmic component
BTD91_19200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTD91_19205	COG4605	iron ion homeostasis
BTD91_19210	COG4604	ABC transporter, ATP-binding protein
BTD91_19215	COG0583	DNA-binding transcription factor activity
BTD91_19220	COG2814	Major facilitator Superfamily
BTD91_19245	COG0840	transmembrane signaling receptor activity
BTD91_19250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BTD91_19265	COG3706	GGDEF domain
BTD91_19265	COG4251	negative regulation of phosphorylation
BTD91_19265	COG5001	Diguanylate cyclase
BTD91_19265	COG2203	Gaf domain
BTD91_19270	COG2897	thiosulfate sulfurtransferase activity
BTD91_19290	COG0302	gtp cyclohydrolase
BTD91_19300	COG4681	YaeQ
BTD91_19305	COG1278	Cold shock
BTD91_19310	COG2133	pyrroloquinoline quinone binding
BTD91_19315	COG2814	Major facilitator Superfamily
BTD91_19325	COG4774	siderophore transport
BTD91_19340	COG1250	3-hydroxyacyl-CoA dehydrogenase
BTD91_19340	COG1024	Enoyl-CoA hydratase
BTD91_19345	COG0446	pyridine nucleotide-disulphide oxidoreductase
BTD91_19345	COG1902	pentaerythritol trinitrate reductase activity
BTD91_19360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTD91_19365	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTD91_19400	COG2824	Alkylphosphonate utilization operon protein PhnA
BTD91_19410	COG0765	amino acid transport
BTD91_19415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTD91_19420	COG0765	amino acid transport
BTD91_19425	COG1126	abc transporter atp-binding protein
BTD91_19430	COG1979	alcohol dehydrogenase
BTD91_19435	COG2207	Transcriptional regulator
BTD91_19455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTD91_19470	COG3059	membrane
BTD91_19480	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BTD91_19500	COG1686	Belongs to the peptidase S11 family
BTD91_19510	COG0564	pseudouridine synthase activity
BTD91_19520	COG2130	NADP-dependent
BTD91_19525	COG1309	transcriptional regulator
BTD91_19530	COG0545	Peptidyl-prolyl cis-trans isomerase
BTD91_19550	COG3604	Transcriptional regulator
BTD91_19555	COG1017	nitric oxide dioxygenase activity
BTD91_19555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BTD91_19565	COG0038	chloride channel
BTD91_19570	COG0523	cobalamin synthesis protein
BTD91_19575	COG0513	Belongs to the DEAD box helicase family
BTD91_19630	COG0183	Belongs to the thiolase family
BTD91_19650	COG3005	denitrification pathway
BTD91_19660	COG0243	molybdopterin cofactor binding
BTD91_19675	COG3850	Histidine kinase
BTD91_19680	COG2197	response regulator
BTD91_19685	COG3069	C4-dicarboxylate transmembrane transporter activity
BTD91_19690	COG3706	GGDEF domain
BTD91_19705	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BTD91_19745	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BTD91_19750	COG0494	nUDIX hydrolase
BTD91_19755	COG0714	Associated with various cellular activities
BTD91_19760	COG2425	protein containing a von Willebrand factor type A (vWA) domain
BTD91_19820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BTD91_19850	COG2116	formate transmembrane transporter activity
BTD91_19855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BTD91_19855	COG1648	precorrin-2 dehydrogenase activity
BTD91_19870	COG0745	RESPONSE REGULATOR receiver
BTD91_19875	COG2205	protein histidine kinase activity
BTD91_19880	COG1301	dicarboxylic acid transport
BTD91_19885	COG4774	siderophore transport
BTD91_19895	COG0811	peptide transport
BTD91_19900	COG0811	peptide transport
BTD91_19905	COG0848	biopolymer transport protein
BTD91_19950	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTD91_19955	COG1121	(ABC) transporter
BTD91_19960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTD91_19960	COG1321	iron dependent repressor
BTD91_19985	COG0534	Mate efflux family protein
BTD91_19995	COG0477	Major facilitator Superfamily
BTD91_20010	COG3118	belongs to the thioredoxin family
BTD91_20015	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTD91_20045	COG1328	CTP reductase activity
BTD91_20050	COG0602	queuosine metabolic process
BTD91_20070	COG4067	protein conserved in archaea
BTD91_20070	COG0189	ligase activity
BTD91_20075	COG0488	(ABC) transporter
BTD91_20095	COG0725	ABC transporter, periplasmic molybdate-binding protein
BTD91_20100	COG4149	molybdate abc transporter
BTD91_20105	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BTD91_20115	COG2203	Gaf domain
BTD91_20115	COG5001	Diguanylate cyclase
BTD91_20115	COG4251	negative regulation of phosphorylation
BTD91_20115	COG3706	GGDEF domain
BTD91_20125	COG3706	GGDEF domain
BTD91_20140	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BTD91_20145	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BTD91_20170	COG3140	Belongs to the UPF0181 family
BTD91_20175	COG0023	Translation Initiation Factor
BTD91_20190	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTD91_20195	COG3266	domain, Protein
BTD91_20200	COG0045	succinate-CoA ligase (ADP-forming) activity
BTD91_20200	COG1042	CoA-binding domain protein
BTD91_20200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BTD91_20205	COG0583	DNA-binding transcription factor activity
BTD91_20210	COG4771	TonB-dependent receptor
BTD91_20210	COG1629	transport
BTD91_20225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BTD91_20230	COG1984	allophanate hydrolase subunit 2
BTD91_20240	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BTD91_20245	COG4181	ATPase activity
BTD91_20255	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BTD91_20260	COG5001	Diguanylate cyclase
BTD91_20260	COG1716	ATPase activity
BTD91_20270	COG0768	penicillin binding
BTD91_20275	COG0484	heat shock protein binding
BTD91_20300	COG4533	DNA binding
BTD91_20310	COG2050	protein possibly involved in aromatic compounds catabolism
BTD91_20315	COG0501	Belongs to the peptidase M48B family
BTD91_20325	COG2067	long-chain fatty acid transport protein
BTD91_20330	COG2267	carboxylic ester hydrolase activity
BTD91_20340	COG0583	DNA-binding transcription factor activity
BTD91_20350	COG1566	PFAM secretion protein HlyD family protein
BTD91_20360	COG0513	Belongs to the DEAD box helicase family
BTD91_20370	COG0861	Integral membrane protein TerC family
BTD91_20375	COG0737	Belongs to the 5'-nucleotidase family
BTD91_20380	COG3593	DNA synthesis involved in DNA repair
BTD91_20390	COG0583	DNA-binding transcription factor activity
BTD91_20395	COG2116	formate transmembrane transporter activity
BTD91_20405	COG3038	cytochrome b561
BTD91_20440	COG0006	proline dipeptidase activity
BTD91_20445	COG3608	succinylglutamate desuccinylase aspartoacylase
BTD91_20450	COG1522	sequence-specific DNA binding
BTD91_20455	COG1012	belongs to the aldehyde dehydrogenase family
BTD91_20460	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BTD91_20465	COG0513	Belongs to the DEAD box helicase family
BTD91_20470	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BTD91_20475	COG0814	amino acid
BTD91_20500	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BTD91_20505	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BTD91_20510	COG3706	GGDEF domain
BTD91_20515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BTD91_20545	COG0509	glycine decarboxylation via glycine cleavage system
BTD91_20560	COG0500	methyltransferase
BTD91_20635	COG5507	3-demethylubiquinone-9 3-methyltransferase
BTD91_20685	COG3422	double-strand break repair
BTD91_20710	COG0582	viral genome integration into host DNA