locus-tag	class	description
ECB94_00010	COG0488	(ABC) transporter
ECB94_00015	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ECB94_00045	COG0243	molybdopterin cofactor binding
ECB94_00045	COG3383	formate dehydrogenase (NAD+) activity
ECB94_00050	COG0437	4 iron, 4 sulfur cluster binding
ECB94_00065	COG0004	ammonium transporteR
ECB94_00070	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ECB94_00075	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECB94_00080	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECB94_00085	COG1177	transmembrane transport
ECB94_00090	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECB94_00095	COG3842	ATPase activity
ECB94_00120	COG0589	response to stress
ECB94_00125	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECB94_00140	COG2217	Heavy metal translocating P-type atpase
ECB94_00150	COG2010	Cytochrome c
ECB94_00165	COG3278	Belongs to the heme-copper respiratory oxidase family
ECB94_00175	COG1132	(ABC) transporter
ECB94_00180	COG2274	protein secretion by the type I secretion system
ECB94_00525	COG3120	sequence-specific DNA binding
ECB94_00530	COG1067	ATP-dependent peptidase activity
ECB94_00550	COG0488	(ABC) transporter
ECB94_00560	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ECB94_00560	COG0116	Belongs to the methyltransferase superfamily
ECB94_00590	COG0308	aminopeptidase N
ECB94_00605	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
ECB94_00610	COG1956	GAF domain-containing protein
ECB94_00615	COG1132	(ABC) transporter
ECB94_00620	COG2995	paraquat-inducible protein a
ECB94_00625	COG3008	intermembrane lipid transfer
ECB94_00635	COG2996	Protein conserved in bacteria
ECB94_00655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECB94_00670	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECB94_00675	COG4597	amino acid ABC transporter
ECB94_00680	COG0765	amino acid transport
ECB94_00685	COG1126	abc transporter atp-binding protein
ECB94_00690	COG0670	Belongs to the BI1 family
ECB94_00695	COG2920	part of a sulfur-relay system
ECB94_00700	COG1254	Belongs to the acylphosphatase family
ECB94_00705	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ECB94_00715	COG2885	chlorophyll binding
ECB94_00715	COG3047	cAMP biosynthetic process
ECB94_00730	COG0602	queuosine metabolic process
ECB94_00735	COG0561	phosphatase activity
ECB94_00740	COG1597	lipid kinase activity
ECB94_00760	COG0840	transmembrane signaling receptor activity
ECB94_00765	COG0791	NLP P60 protein
ECB94_00810	COG0454	-acetyltransferase
ECB94_00830	COG0668	transmembrane transport
ECB94_00855	COG4667	esterase of the alpha-beta hydrolase superfamily
ECB94_00885	COG4235	cytochrome complex assembly
ECB94_00885	COG3088	subunit of a heme lyase
ECB94_00890	COG1138	Cytochrome C-type biogenesis protein
ECB94_00895	COG3301	Polysulphide reductase, NrfD
ECB94_00900	COG0437	4 iron, 4 sulfur cluster binding
ECB94_00920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECB94_00930	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ECB94_00975	COG0072	phenylalanine-tRNA ligase activity
ECB94_00975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECB94_00985	COG2226	methyltransferase
ECB94_01000	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECB94_01020	COG0668	transmembrane transport
ECB94_01025	COG2814	Major facilitator Superfamily
ECB94_01040	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ECB94_01055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ECB94_01060	COG2146	nitrite reductase [NAD(P)H] activity
ECB94_01065	COG2116	formate transmembrane transporter activity
ECB94_01070	COG1648	precorrin-2 dehydrogenase activity
ECB94_01070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ECB94_01075	COG2885	chlorophyll binding
ECB94_01125	COG4964	Belongs to the GSP D family
ECB94_01160	COG3047	cAMP biosynthetic process
ECB94_01160	COG2885	chlorophyll binding
ECB94_01200	COG0455	bacterial-type flagellum organization
ECB94_01210	COG4964	Belongs to the GSP D family
ECB94_01230	COG0583	DNA-binding transcription factor activity
ECB94_01240	COG2375	cellular response to nickel ion
ECB94_01255	COG0814	amino acid
ECB94_01285	COG0583	DNA-binding transcription factor activity
ECB94_01305	COG3501	Rhs element vgr protein
ECB94_01405	COG2815	serine threonine protein kinase
ECB94_01405	COG0515	serine threonine protein kinase
ECB94_01425	COG0247	lactate metabolic process
ECB94_01425	COG0277	FAD linked oxidase domain protein
ECB94_01470	COG0281	malic enzyme
ECB94_01480	COG2949	membrane
ECB94_01490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_01500	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECB94_01515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ECB94_01525	COG0492	ferredoxin-NADP+ reductase activity
ECB94_01530	COG4988	ABC transporter
ECB94_01535	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ECB94_01540	COG1253	flavin adenine dinucleotide binding
ECB94_01545	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ECB94_01570	COG3070	regulator of competence-specific genes
ECB94_01580	COG2431	L-lysine efflux transmembrane transporter activity
ECB94_01590	COG0076	glutamate decarboxylase activity
ECB94_01595	COG1737	Transcriptional regulator
ECB94_01600	COG1454	alcohol dehydrogenase
ECB94_01600	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_01605	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECB94_01615	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ECB94_01620	COG1960	acyl-CoA dehydrogenase activity
ECB94_01625	COG1309	transcriptional regulator
ECB94_01630	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ECB94_01645	COG1136	(ABC) transporter
ECB94_01650	COG0702	epimerase
ECB94_01660	COG2814	Major facilitator Superfamily
ECB94_01670	COG1061	Type III restriction enzyme res subunit
ECB94_01685	COG2205	protein histidine kinase activity
ECB94_01725	COG0714	Associated with various cellular activities
ECB94_01730	COG3119	arylsulfatase activity
ECB94_01740	COG0641	radical SAM
ECB94_01755	COG0583	DNA-binding transcription factor activity
ECB94_01775	COG0583	DNA-binding transcription factor activity
ECB94_01815	COG2207	Transcriptional regulator
ECB94_01820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_01825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ECB94_01835	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECB94_01845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_01850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_01855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_01855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_01855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECB94_01860	COG4702	Belongs to the UPF0303 family
ECB94_01865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECB94_01870	COG1940	carbohydrate kinase activity
ECB94_01880	COG1129	ABC transporter
ECB94_01890	COG0457	Tetratricopeptide repeat
ECB94_01895	COG2017	converts alpha-aldose to the beta-anomer
ECB94_01915	COG1132	(ABC) transporter
ECB94_01920	COG1132	(ABC) transporter
ECB94_01930	COG3608	succinylglutamate desuccinylase aspartoacylase
ECB94_01935	COG4608	Belongs to the ABC transporter superfamily
ECB94_01940	COG0444	Belongs to the ABC transporter superfamily
ECB94_01945	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECB94_01950	COG0601	transmembrane transport
ECB94_01965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECB94_01975	COG1072	(Pantothenic acid kinase))
ECB94_01985	COG1063	alcohol dehydrogenase
ECB94_01990	COG2213	PTS system mannitol-specific
ECB94_01995	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_02010	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ECB94_02015	COG1845	cytochrome c oxidase, subunit III
ECB94_02020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ECB94_02025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ECB94_02030	COG0583	DNA-binding transcription factor activity
ECB94_02060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ECB94_02065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ECB94_02125	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_02135	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ECB94_02140	COG0583	DNA-binding transcription factor activity
ECB94_02145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_02195	COG3040	lipid binding
ECB94_02200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ECB94_02205	COG0584	glycerophosphoryl diester phosphodiesterase
ECB94_02220	COG2195	Cleaves the N-terminal amino acid of tripeptides
ECB94_02250	COG1943	Transposase
ECB94_02255	COG0318	PFAM AMP-dependent synthetase and ligase
ECB94_02260	COG3063	Type IV pilus biogenesis stability protein PilW
ECB94_02265	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ECB94_02270	COG1451	nucleotide metabolic process
ECB94_02285	COG0679	Auxin Efflux Carrier
ECB94_02290	COG0149	triose-phosphate isomerase activity
ECB94_02295	COG1461	Dihydroxyacetone kinase
ECB94_02300	COG2376	Dihydroxyacetone kinase
ECB94_02320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECB94_02325	COG0698	ribose 5-phosphate isomerase
ECB94_02330	COG1494	fructose-1,6-bisphosphatase
ECB94_02345	COG1686	Belongs to the peptidase S11 family
ECB94_02350	COG1301	dicarboxylic acid transport
ECB94_02355	COG1252	NADH dehydrogenase
ECB94_02360	COG2199	diguanylate cyclase activity
ECB94_02370	COG4134	Bacterial extracellular solute-binding protein
ECB94_02375	COG4135	transport system, permease component
ECB94_02380	COG4136	ATPase activity
ECB94_02385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ECB94_02390	COG1403	HNH endonuclease
ECB94_02395	COG0656	L-ascorbic acid biosynthetic process
ECB94_02415	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ECB94_02420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ECB94_02425	COG1609	Transcriptional regulator
ECB94_02445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECB94_02450	COG1760	l-serine dehydratase
ECB94_02465	COG0395	ABC-type sugar transport system, permease component
ECB94_02475	COG3842	ATPase activity
ECB94_02480	COG3842	ATPase activity
ECB94_02485	COG3284	Transcriptional regulator
ECB94_02490	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECB94_02495	COG0583	DNA-binding transcription factor activity
ECB94_02505	COG3768	UPF0283 membrane protein
ECB94_02510	COG3106	COG3106 Predicted ATPase
ECB94_02530	COG5002	protein histidine kinase activity
ECB94_02530	COG0784	Response regulator, receiver
ECB94_02545	COG1716	ATPase activity
ECB94_02545	COG5001	Diguanylate cyclase
ECB94_02570	COG0494	nUDIX hydrolase
ECB94_02575	COG0814	amino acid
ECB94_02580	COG1760	l-serine dehydratase
ECB94_02585	COG0720	synthase
ECB94_02595	COG0463	Glycosyl transferase, family 2
ECB94_02610	COG0017	Asparaginyl-tRNA synthetase
ECB94_02620	COG1448	Aminotransferase
ECB94_02635	COG0840	transmembrane signaling receptor activity
ECB94_02645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECB94_02650	COG1846	Transcriptional regulator
ECB94_02675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ECB94_02690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ECB94_02695	COG3108	Peptidase M15
ECB94_02700	COG2989	Protein conserved in bacteria
ECB94_02725	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ECB94_02735	COG0513	Belongs to the DEAD box helicase family
ECB94_02750	COG3302	dmso reductase anchor subunit
ECB94_02755	COG0437	4 iron, 4 sulfur cluster binding
ECB94_02760	COG0243	molybdopterin cofactor binding
ECB94_02780	COG3710	Transcriptional regulator
ECB94_02805	COG1263	PTS System
ECB94_02805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_02810	COG1621	beta-fructofuranosidase activity
ECB94_02825	COG0019	diaminopimelate decarboxylase activity
ECB94_02840	COG0307	riboflavin synthase, alpha
ECB94_02870	COG0322	excinuclease ABC activity
ECB94_02875	COG2197	response regulator
ECB94_02880	COG0417	DNA replication proofreading
ECB94_02890	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ECB94_02900	COG0671	phosphoesterase, PA-phosphatase related
ECB94_02910	COG1227	inorganic diphosphatase activity
ECB94_02925	COG0243	molybdopterin cofactor binding
ECB94_02930	COG3005	denitrification pathway
ECB94_02935	COG4459	periplasmic nitrate reductase
ECB94_02940	COG0390	transport system, permease component
ECB94_02945	COG2116	formate transmembrane transporter activity
ECB94_02965	COG0583	DNA-binding transcription factor activity
ECB94_02975	COG1435	thymidine kinase activity
ECB94_02980	COG0215	cysteine-tRNA ligase activity
ECB94_02985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECB94_02995	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ECB94_03045	COG0438	transferase activity, transferring glycosyl groups
ECB94_03075	COG0438	transferase activity, transferring glycosyl groups
ECB94_03085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ECB94_03090	COG2076	Multidrug Resistance protein
ECB94_03095	COG2076	Multidrug Resistance protein
ECB94_03100	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ECB94_03105	COG0726	polysaccharide deacetylase
ECB94_03110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ECB94_03110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECB94_03115	COG0463	Glycosyl transferase, family 2
ECB94_03120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ECB94_03160	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECB94_03165	COG1199	ATP-dependent helicase activity
ECB94_03170	COG0730	response to heat
ECB94_03185	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ECB94_03190	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
ECB94_03200	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ECB94_03205	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ECB94_03210	COG0745	RESPONSE REGULATOR receiver
ECB94_03225	COG3070	regulator of competence-specific genes
ECB94_03245	COG0297	glycogen (starch) synthase activity
ECB94_03250	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ECB94_03255	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECB94_03270	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ECB94_03275	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ECB94_03280	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ECB94_03285	COG0542	response to heat
ECB94_03295	COG1278	Cold shock
ECB94_03305	COG1187	pseudouridine synthase activity
ECB94_03310	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ECB94_03325	COG1132	(ABC) transporter
ECB94_03330	COG0658	competence protein
ECB94_03330	COG2333	competence protein COMEC
ECB94_03340	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECB94_03345	COG1136	(ABC) transporter
ECB94_03350	COG4591	ABC-type transport system involved in lipoprotein release permease component
ECB94_03360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ECB94_03375	COG1252	NADH dehydrogenase
ECB94_03380	COG4932	domain protein
ECB94_03380	COG5492	domain, Protein
ECB94_03405	COG5633	Lipoprotein
ECB94_03415	COG0537	adenosine 5'-monophosphoramidase activity
ECB94_03435	COG0583	DNA-binding transcription factor activity
ECB94_03440	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_03450	COG0280	phosphate acetyltransferase
ECB94_03455	COG0019	diaminopimelate decarboxylase activity
ECB94_03465	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ECB94_03490	COG0515	serine threonine protein kinase
ECB94_03490	COG2815	serine threonine protein kinase
ECB94_03495	COG2223	nitrite transmembrane transporter activity
ECB94_03505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ECB94_03510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ECB94_03510	COG1648	precorrin-2 dehydrogenase activity
ECB94_03515	COG0243	molybdopterin cofactor binding
ECB94_03520	COG0569	domain protein
ECB94_03525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ECB94_03530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECB94_03540	COG0561	phosphatase activity
ECB94_03545	COG0314	molybdopterin synthase activity
ECB94_03550	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ECB94_03555	COG0315	cyclic pyranopterin monophosphate synthase activity
ECB94_03560	COG0521	Mo-molybdopterin cofactor biosynthetic process
ECB94_03565	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ECB94_03570	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ECB94_03575	COG2198	Histidine kinase
ECB94_03580	COG2204	response regulator
ECB94_03585	COG0556	nucleotide-excision repair
ECB94_03595	COG4657	Part of a membrane complex involved in electron transport
ECB94_03600	COG2878	Part of a membrane complex involved in electron transport
ECB94_03605	COG4656	Part of a membrane complex involved in electron transport
ECB94_03620	COG4660	Part of a membrane complex involved in electron transport
ECB94_03625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ECB94_03630	COG0346	lactoylglutathione lyase activity
ECB94_03645	COG2056	Na+-H+ antiporter family
ECB94_03650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ECB94_03670	COG1454	alcohol dehydrogenase
ECB94_03670	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_03675	COG2095	MarC family integral membrane protein
ECB94_03680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECB94_03685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECB94_03700	COG3081	Nucleoid-associated protein
ECB94_03705	COG3082	Protein of unknown function (DUF1414)
ECB94_03710	COG3083	sulfuric ester hydrolase activity
ECB94_03735	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ECB94_03990	COG0494	nUDIX hydrolase
ECB94_03995	COG0123	including yeast histone deacetylase and acetoin utilization protein
ECB94_04005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ECB94_04010	COG0778	Nitroreductase
ECB94_04015	COG1902	pentaerythritol trinitrate reductase activity
ECB94_04015	COG0446	pyridine nucleotide-disulphide oxidoreductase
ECB94_04020	COG0616	signal peptide processing
ECB94_04025	COG0252	asparaginase activity
ECB94_04030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ECB94_04075	COG0582	viral genome integration into host DNA
ECB94_04105	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ECB94_04110	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECB94_04120	COG2982	Protein involved in outer membrane biogenesis
ECB94_04125	COG0572	uridine kinase
ECB94_04130	COG0489	protein tyrosine kinase activity
ECB94_04135	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECB94_04135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ECB94_04145	COG2186	Transcriptional regulator
ECB94_04160	COG0653	protein targeting
ECB94_04165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ECB94_04170	COG0366	Alpha amylase catalytic
ECB94_04180	COG4120	Belongs to the binding-protein-dependent transport system permease family
ECB94_04190	COG2133	pyrroloquinoline quinone binding
ECB94_04200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECB94_04205	COG0280	phosphate acetyltransferase
ECB94_04205	COG0857	belongs to the CobB CobQ family
ECB94_04210	COG0435	Glutathione S-transferase
ECB94_04220	COG0444	Belongs to the ABC transporter superfamily
ECB94_04225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECB94_04230	COG0601	transmembrane transport
ECB94_04245	COG0318	PFAM AMP-dependent synthetase and ligase
ECB94_04255	COG0673	inositol 2-dehydrogenase activity
ECB94_04265	COG4206	TonB-dependent receptor
ECB94_04280	COG3101	peptidyl-lysine hydroxylation
ECB94_04285	COG2860	membrane
ECB94_04295	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ECB94_04300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ECB94_04305	COG2890	protein-(glutamine-N5) methyltransferase activity
ECB94_04310	COG2840	Smr protein MutS2
ECB94_04315	COG2062	phosphohistidine phosphatase, SixA
ECB94_04325	COG1250	3-hydroxyacyl-CoA dehydrogenase
ECB94_04325	COG1024	Enoyl-CoA hydratase
ECB94_04330	COG0183	Belongs to the thiolase family
ECB94_04350	COG2067	long-chain fatty acid transport protein
ECB94_04355	COG2853	Lipoprotein
ECB94_04370	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ECB94_04375	COG1138	Cytochrome C-type biogenesis protein
ECB94_04385	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECB94_04390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECB94_04395	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ECB94_04400	COG4133	protoheme IX ABC transporter activity
ECB94_04410	COG0835	chemotaxis
ECB94_04420	COG1192	Involved in chromosome partitioning
ECB94_04425	COG2201	protein-glutamate methylesterase activity
ECB94_04430	COG0643	Histidine kinase
ECB94_04430	COG2198	Histidine kinase
ECB94_04435	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ECB94_04450	COG0455	bacterial-type flagellum organization
ECB94_04480	COG1987	bacterial-type flagellum assembly
ECB94_04530	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECB94_04540	COG1677	Flagellar hook-basal body complex protein FliE
ECB94_04545	COG2204	response regulator
ECB94_04550	COG4191	Histidine kinase
ECB94_04555	COG2204	response regulator
ECB94_04560	COG1516	flagellar protein fliS
ECB94_04570	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ECB94_04575	COG1334	flagellar protein FlaG
ECB94_04585	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECB94_04605	COG1705	Flagellar rod assembly protein muramidase FlgJ
ECB94_04605	COG3951	Flagellar rod assembly protein muramidase FlgJ
ECB94_04615	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ECB94_04620	COG4786	Flagellar basal body rod
ECB94_04625	COG4787	bacterial-type flagellum-dependent cell motility
ECB94_04630	COG1749	Flagellar hook protein flgE
ECB94_04635	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ECB94_04640	COG1558	bacterial-type flagellum-dependent cell motility
ECB94_04645	COG1815	bacterial-type flagellum-dependent cell motility
ECB94_04655	COG0835	chemotaxis
ECB94_04655	COG0784	Response regulator, receiver
ECB94_04725	COG1733	regulation of RNA biosynthetic process
ECB94_04750	COG1846	Transcriptional regulator
ECB94_04760	COG0772	Belongs to the SEDS family
ECB94_04765	COG0586	Pfam SNARE associated Golgi protein
ECB94_04775	COG3111	PFAM Bacterial OB fold (BOF) protein
ECB94_04780	COG4821	SIS domain
ECB94_04795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECB94_04810	COG2271	Major facilitator Superfamily
ECB94_04815	COG3851	Histidine kinase
ECB94_04820	COG2197	response regulator
ECB94_04830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECB94_04835	COG1757	Na H antiporter
ECB94_04845	COG0513	Belongs to the DEAD box helicase family
ECB94_04860	COG2239	Acts as a magnesium transporter
ECB94_04890	COG1024	Enoyl-CoA hydratase
ECB94_04900	COG0204	Acyl-transferase
ECB94_04905	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ECB94_04910	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ECB94_04935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECB94_04935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ECB94_04945	COG0564	pseudouridine synthase activity
ECB94_04950	COG3098	single-species biofilm formation
ECB94_04975	COG1671	Belongs to the UPF0178 family
ECB94_04980	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ECB94_05000	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ECB94_05005	COG2252	PERMEase
ECB94_05010	COG2195	Cleaves the N-terminal amino acid of tripeptides
ECB94_05025	COG0733	neurotransmitter:sodium symporter activity
ECB94_05035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECB94_05045	COG2991	Protein conserved in bacteria
ECB94_05050	COG1477	protein flavinylation
ECB94_05055	COG2871	sodium ion transport
ECB94_05060	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ECB94_05070	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ECB94_05080	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ECB94_05085	COG0271	Belongs to the BolA IbaG family
ECB94_05100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECB94_05105	COG2211	Major facilitator Superfamily
ECB94_05115	COG1595	DNA-templated transcription, initiation
ECB94_05130	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ECB94_05135	COG0693	protein deglycase activity
ECB94_05140	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ECB94_05145	COG2166	iron-sulfur cluster assembly
ECB94_05150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ECB94_05155	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ECB94_05175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ECB94_05180	COG1074	ATP-dependent DNA helicase activity
ECB94_05185	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ECB94_05195	COG0583	DNA-binding transcription factor activity
ECB94_05200	COG3141	response to X-ray
ECB94_05205	COG2171	N-acyltransferase activity
ECB94_05210	COG0250	Participates in transcription elongation, termination and antitermination
ECB94_05215	COG3104	oligopeptide transport
ECB94_05220	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ECB94_05230	COG0326	Molecular chaperone. Has ATPase activity
ECB94_05235	COG3710	Transcriptional regulator
ECB94_05245	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECB94_05255	COG2837	iron assimilation
ECB94_05280	COG1393	Belongs to the ArsC family
ECB94_05285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECB94_05290	COG1876	peptidase activity
ECB94_05305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ECB94_05310	COG2716	regulation of RNA biosynthetic process
ECB94_05315	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ECB94_05330	COG4783	chaperone-mediated protein folding
ECB94_05335	COG1393	Belongs to the ArsC family
ECB94_05355	COG2233	PERMEase
ECB94_05360	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ECB94_05370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ECB94_05375	COG0121	glutamine amidotransferase
ECB94_05385	COG1960	acyl-CoA dehydrogenase activity
ECB94_05395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ECB94_05405	COG2226	methyltransferase
ECB94_05415	COG0741	lytic transglycosylase activity
ECB94_05415	COG1388	LysM domain
ECB94_05425	COG0347	Belongs to the P(II) protein family
ECB94_05440	COG0825	malonyl-CoA metabolic process
ECB94_05445	COG0587	DNA-directed DNA polymerase activity
ECB94_05455	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ECB94_05470	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ECB94_05475	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ECB94_05480	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECB94_05485	COG0750	zinc metalloprotease
ECB94_05490	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ECB94_05495	COG0575	Belongs to the CDS family
ECB94_05520	COG0052	Belongs to the universal ribosomal protein uS2 family
ECB94_05525	COG0024	Methionine aminopeptidase
ECB94_05540	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ECB94_05545	COG1720	tRNA m6t6A37 methyltransferase activity
ECB94_05550	COG0442	prolyl-tRNA aminoacylation
ECB94_05565	COG0047	phosphoribosylformylglycinamidine synthase activity
ECB94_05565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ECB94_05570	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ECB94_05575	COG0590	tRNA wobble adenosine to inosine editing
ECB94_05580	COG0583	DNA-binding transcription factor activity
ECB94_05585	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ECB94_05590	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ECB94_05595	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ECB94_05625	COG0484	heat shock protein binding
ECB94_05635	COG1301	dicarboxylic acid transport
ECB94_05640	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ECB94_05650	COG0497	DNA recombination
ECB94_05655	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECB94_05660	COG2914	Belongs to the UPF0125 (RnfH) family
ECB94_05665	COG2867	negative regulation of translational initiation
ECB94_05680	COG1289	transmembrane transporter activity
ECB94_05715	COG1116	anion transmembrane transporter activity
ECB94_05720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ECB94_05725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ECB94_05730	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ECB94_05735	COG1115	amino acid carrier protein
ECB94_05740	COG1584	GPR1 FUN34 yaaH family protein
ECB94_05745	COG0519	Catalyzes the synthesis of GMP from XMP
ECB94_05745	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ECB94_05750	COG0517	IMP dehydrogenase activity
ECB94_05750	COG0516	GMP reductase activity
ECB94_05765	COG5001	Diguanylate cyclase
ECB94_05765	COG3300	MHYT domain
ECB94_05775	COG1160	GTP binding
ECB94_05780	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECB94_05785	COG2976	Protein conserved in bacteria
ECB94_05795	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ECB94_05805	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ECB94_05815	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ECB94_05820	COG2975	iron-sulfur cluster assembly
ECB94_05825	COG0633	Ferredoxin
ECB94_05830	COG0443	Heat shock 70 kDa protein
ECB94_05840	COG0316	Belongs to the HesB IscA family
ECB94_05845	COG0822	iron-sulfur transferase activity
ECB94_05850	COG1104	cysteine desulfurase activity
ECB94_05860	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ECB94_05865	COG0483	inositol monophosphate 1-phosphatase activity
ECB94_05870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECB94_05875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECB94_05880	COG1862	Preprotein translocase
ECB94_05890	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ECB94_05895	COG0517	IMP dehydrogenase activity
ECB94_05900	COG0583	DNA-binding transcription factor activity
ECB94_05905	COG0450	alkyl hydroperoxide reductase
ECB94_05925	COG0704	Plays a role in the regulation of phosphate uptake
ECB94_05930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ECB94_05935	COG0581	inorganic phosphate transmembrane transporter activity
ECB94_05940	COG0573	inorganic phosphate transmembrane transporter activity
ECB94_05945	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ECB94_05950	COG0248	Ppx GppA phosphatase
ECB94_05960	COG5002	protein histidine kinase activity
ECB94_05965	COG0745	RESPONSE REGULATOR receiver
ECB94_05980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECB94_06030	COG0542	response to heat
ECB94_06040	COG0564	pseudouridine synthase activity
ECB94_06045	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ECB94_06050	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ECB94_06055	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECB94_06060	COG1605	Chorismate mutase
ECB94_06060	COG0077	Prephenate dehydratase
ECB94_06070	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ECB94_06085	COG0488	(ABC) transporter
ECB94_06090	COG0739	heme binding
ECB94_06095	COG1605	Chorismate mutase
ECB94_06095	COG0287	Prephenate dehydrogenase
ECB94_06100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECB94_06105	COG3275	phosphorelay sensor kinase activity
ECB94_06110	COG3279	Response regulator of the LytR AlgR family
ECB94_06115	COG1472	Belongs to the glycosyl hydrolase 3 family
ECB94_06120	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ECB94_06135	COG1966	Carbon starvation protein
ECB94_06150	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ECB94_06155	COG0083	homoserine kinase activity
ECB94_06170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ECB94_06180	COG0745	RESPONSE REGULATOR receiver
ECB94_06190	COG0784	Response regulator, receiver
ECB94_06190	COG2198	Histidine kinase
ECB94_06190	COG5002	protein histidine kinase activity
ECB94_06195	COG1242	4 iron, 4 sulfur cluster binding
ECB94_06200	COG0070	glutamate synthase
ECB94_06200	COG0069	glutamate synthase activity
ECB94_06200	COG0067	glutamate synthase
ECB94_06210	COG0069	glutamate synthase activity
ECB94_06210	COG0067	glutamate synthase
ECB94_06210	COG0070	glutamate synthase
ECB94_06215	COG0493	'glutamate synthase
ECB94_06235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ECB94_06240	COG2860	membrane
ECB94_06245	COG1119	ATPase activity
ECB94_06255	COG0583	DNA-binding transcription factor activity
ECB94_06260	COG0730	response to heat
ECB94_06285	COG0494	nUDIX hydrolase
ECB94_06300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ECB94_06305	COG0849	cell division
ECB94_06310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ECB94_06315	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ECB94_06320	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ECB94_06325	COG0772	Belongs to the SEDS family
ECB94_06335	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ECB94_06340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ECB94_06345	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECB94_06350	COG0768	penicillin binding
ECB94_06355	COG3116	cell division
ECB94_06370	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ECB94_06375	COG3107	peptidoglycan biosynthetic process
ECB94_06380	COG0792	nuclease activity
ECB94_06385	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ECB94_06400	COG0028	Belongs to the TPP enzyme family
ECB94_06415	COG0316	Belongs to the HesB IscA family
ECB94_06420	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ECB94_06425	COG0628	permease
ECB94_06440	COG1049	propionate catabolic process, 2-methylcitrate cycle
ECB94_06445	COG1752	Esterase of the alpha-beta hydrolase superfamily
ECB94_06450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ECB94_06455	COG1643	Atp-dependent helicase
ECB94_06465	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECB94_06470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ECB94_06480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ECB94_06485	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ECB94_06500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECB94_06505	COG3025	triphosphatase activity
ECB94_06510	COG1392	Phosphate transport regulator
ECB94_06515	COG0306	phosphate transporter
ECB94_06520	COG4991	sh3 domain protein
ECB94_06525	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECB94_06530	COG4942	peptidase
ECB94_06530	COG1388	LysM domain
ECB94_06545	COG0585	pseudouridine synthase activity
ECB94_06550	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ECB94_06555	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ECB94_06560	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ECB94_06580	COG2203	Gaf domain
ECB94_06580	COG2199	diguanylate cyclase activity
ECB94_06585	COG0798	PFAM Bile acid sodium symporter
ECB94_06605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECB94_06610	COG0640	Transcriptional regulator
ECB94_06615	COG1737	Transcriptional regulator
ECB94_06625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_06625	COG1263	PTS System
ECB94_06630	COG0698	ribose 5-phosphate isomerase
ECB94_06635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECB94_06650	COG0469	pyruvate kinase activity
ECB94_06670	COG1459	type II secretion system
ECB94_06675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECB94_06735	COG2969	positive regulation of protein catabolic process
ECB94_06740	COG0625	glutathione transferase activity
ECB94_06745	COG2857	Cytochrome c1
ECB94_06750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ECB94_06755	COG0723	plastoquinol--plastocyanin reductase activity
ECB94_06770	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ECB94_06775	COG3105	Protein conserved in bacteria
ECB94_06780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECB94_06785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ECB94_06790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ECB94_06795	COG0187	DNA topoisomerase II activity
ECB94_06800	COG3150	esterase
ECB94_06810	COG3151	Protein conserved in bacteria
ECB94_06815	COG0494	nUDIX hydrolase
ECB94_06820	COG1538	Outer membrane efflux protein
ECB94_06830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ECB94_06835	COG0842	Transport permease protein
ECB94_06840	COG1131	(ABC) transporter
ECB94_06845	COG0659	secondary active sulfate transmembrane transporter activity
ECB94_06850	COG0288	reversible hydration of carbon dioxide
ECB94_06865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECB94_06870	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECB94_06875	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ECB94_06880	COG2186	Transcriptional regulator
ECB94_06900	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECB94_06905	COG1459	type II secretion system
ECB94_06915	COG0237	dephospho-CoA kinase activity
ECB94_06930	COG0335	large ribosomal subunit rRNA binding
ECB94_06935	COG0336	Belongs to the RNA methyltransferase TrmD family
ECB94_06940	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ECB94_06945	COG0228	four-way junction DNA binding
ECB94_06950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ECB94_06955	COG4137	Cytochrome C assembly protein
ECB94_06960	COG4536	flavin adenine dinucleotide binding
ECB94_06965	COG1410	methionine synthase
ECB94_06965	COG0646	methionine synthase
ECB94_07010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ECB94_07025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECB94_07030	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ECB94_07040	COG1872	DUF167
ECB94_07045	COG0762	integral membrane protein
ECB94_07050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ECB94_07055	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ECB94_07165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ECB94_07210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECB94_07280	COG4228	DNA circulation
ECB94_07325	COG3772	lysozyme
ECB94_07335	COG4695	Portal protein
ECB94_07375	COG4386	tail sheath protein
ECB94_07375	COG4386	tail sheath protein
ECB94_07425	COG0735	belongs to the Fur family
ECB94_07435	COG0795	lipopolysaccharide-transporting ATPase activity
ECB94_07440	COG0795	lipopolysaccharide-transporting ATPase activity
ECB94_07450	COG2927	DNA polymerase III (CHI subunit)
ECB94_07460	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ECB94_07465	COG0527	aspartate kinase activity
ECB94_07490	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ECB94_07520	COG0432	Pfam Uncharacterised protein family UPF0047
ECB94_07525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ECB94_07530	COG0305	Participates in initiation and elongation during chromosome replication
ECB94_07555	COG1446	asparaginase
ECB94_07560	COG1047	Peptidyl-prolyl cis-trans
ECB94_07575	COG2249	NAD(P)H dehydrogenase (quinone) activity
ECB94_07580	COG0488	(ABC) transporter
ECB94_07590	COG1279	arginine transmembrane transporter activity
ECB94_07595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECB94_07600	COG0429	hydrolase of the alpha beta-hydrolase fold
ECB94_07610	COG3954	Phosphoribulokinase
ECB94_07615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ECB94_07635	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ECB94_07640	COG0512	Glutamine amidotransferase of anthranilate synthase
ECB94_07650	COG0180	Tryptophanyl-tRNA synthetase
ECB94_07655	COG0546	phosphoglycolate phosphatase activity
ECB94_07660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ECB94_07665	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ECB94_07710	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ECB94_07720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ECB94_07720	COG0678	peroxiredoxin activity
ECB94_07725	COG0251	oxidation-reduction process
ECB94_07730	COG0165	Argininosuccinate lyase
ECB94_07730	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ECB94_07735	COG0137	argininosuccinate synthase activity
ECB94_07745	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ECB94_07760	COG1695	Transcriptional regulator
ECB94_07765	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ECB94_07770	COG0460	homoserine dehydrogenase
ECB94_07770	COG0527	aspartate kinase activity
ECB94_07775	COG0626	cystathionine gamma-synthase activity
ECB94_07785	COG0281	malic enzyme
ECB94_07795	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ECB94_07800	COG1609	Transcriptional regulator
ECB94_07820	COG1575	Belongs to the MenA family. Type 1 subfamily
ECB94_07825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ECB94_07835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ECB94_07860	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ECB94_07865	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ECB94_07915	COG0438	transferase activity, transferring glycosyl groups
ECB94_07940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ECB94_07945	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ECB94_07945	COG0662	Cupin 2, conserved barrel domain protein
ECB94_07950	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ECB94_07965	COG0859	PFAM glycosyl transferase family 9
ECB94_07970	COG0859	PFAM glycosyl transferase family 9
ECB94_07990	COG0463	Glycosyl transferase, family 2
ECB94_08005	COG1519	Transferase
ECB94_08010	COG3642	lipopolysaccharide core region biosynthetic process
ECB94_08015	COG0859	PFAM glycosyl transferase family 9
ECB94_08020	COG0463	Glycosyl transferase, family 2
ECB94_08025	COG0859	PFAM glycosyl transferase family 9
ECB94_08030	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ECB94_08040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ECB94_08050	COG1561	YicC-like family, N-terminal region
ECB94_08060	COG2194	sulfuric ester hydrolase activity
ECB94_08065	COG2252	PERMEase
ECB94_08075	COG1758	RNA polymerase activity
ECB94_08080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECB94_08085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECB94_08090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ECB94_08100	COG0745	RESPONSE REGULATOR receiver
ECB94_08110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECB94_08130	COG3188	usher protein
ECB94_08145	COG3068	Protein conserved in bacteria
ECB94_08160	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ECB94_08165	COG2816	NAD+ diphosphatase activity
ECB94_08170	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ECB94_08175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ECB94_08185	COG0222	ribosome binding
ECB94_08190	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ECB94_08205	COG0250	Participates in transcription elongation, termination and antitermination
ECB94_08210	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ECB94_08240	COG1072	(Pantothenic acid kinase))
ECB94_08250	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ECB94_08260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECB94_08270	COG0174	glutamine synthetase
ECB94_08280	COG3852	Histidine kinase
ECB94_08295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ECB94_08315	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ECB94_08320	COG2937	Belongs to the GPAT DAPAT family
ECB94_08325	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ECB94_08335	COG1580	Controls the rotational direction of flagella during chemotaxis
ECB94_08340	COG0705	Rhomboid family
ECB94_08355	COG2177	Part of the ABC transporter FtsEX involved in
ECB94_08360	COG2884	Cell division ATP-binding protein ftsE
ECB94_08365	COG0552	protein localization to endoplasmic reticulum
ECB94_08370	COG0742	ribosomal rna small subunit methyltransferase
ECB94_08380	COG2095	MarC family integral membrane protein
ECB94_08415	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
ECB94_08420	COG1280	lysine exporter protein (LysE YggA)
ECB94_08430	COG0561	phosphatase activity
ECB94_08450	COG1011	Hydrolase
ECB94_08470	COG0019	diaminopimelate decarboxylase activity
ECB94_08480	COG1965	Belongs to the frataxin family
ECB94_08485	COG3072	Adenylate cyclase
ECB94_08495	COG1587	Uroporphyrinogen-III synthase
ECB94_08505	COG3071	HemY protein
ECB94_08560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ECB94_08570	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ECB94_08575	COG3118	belongs to the thioredoxin family
ECB94_08585	COG0248	Ppx GppA phosphatase
ECB94_08590	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ECB94_08600	COG0514	ATP-dependent DNA helicase (RecQ)
ECB94_08605	COG2962	Rard protein
ECB94_08615	COG1280	lysine exporter protein (LysE YggA)
ECB94_08620	COG0210	DNA helicase
ECB94_08655	COG0583	DNA-binding transcription factor activity
ECB94_08660	COG0006	proline dipeptidase activity
ECB94_08680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECB94_08685	COG0352	thiamine-phosphate diphosphorylase activity
ECB94_08695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ECB94_08700	COG2132	Multicopper oxidase
ECB94_08750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ECB94_08760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ECB94_08765	COG0408	coproporphyrinogen oxidase activity
ECB94_08775	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ECB94_08785	COG0551	DNA topoisomerase type I activity
ECB94_08795	COG0758	DNA mediated transformation
ECB94_08805	COG0242	peptide deformylase activity
ECB94_08815	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ECB94_08815	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ECB94_08820	COG0569	domain protein
ECB94_08825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ECB94_08830	COG1272	protein, Hemolysin III
ECB94_08835	COG4326	sporulation control protein
ECB94_08845	COG3084	Protein conserved in bacteria
ECB94_08855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ECB94_08860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECB94_08865	COG0204	Acyl-transferase
ECB94_08880	COG0606	chelatase, subunit chli
ECB94_08890	COG3978	acetolactate synthase activity
ECB94_08895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECB94_08900	COG0129	dihydroxy-acid dehydratase activity
ECB94_08910	COG0583	DNA-binding transcription factor activity
ECB94_08915	COG2814	Major facilitator Superfamily
ECB94_08925	COG0765	amino acid transport
ECB94_08935	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ECB94_08940	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ECB94_08945	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ECB94_08950	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ECB94_08955	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ECB94_08960	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ECB94_08970	COG0356	it plays a direct role in the translocation of protons across the membrane
ECB94_08975	COG3312	ion transport
ECB94_08980	COG1475	DNA binding
ECB94_08985	COG1192	Involved in chromosome partitioning
ECB94_08990	COG0357	Ribosomal RNA small subunit methyltransferase G
ECB94_08995	COG0445	tRNA wobble uridine modification
ECB94_09000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ECB94_09010	COG0706	membrane insertase activity
ECB94_09030	COG1126	abc transporter atp-binding protein
ECB94_09050	COG0592	DNA-directed DNA polymerase activity
ECB94_09055	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ECB94_09060	COG0187	DNA topoisomerase II activity
ECB94_09065	COG0071	Belongs to the small heat shock protein (HSP20) family
ECB94_09070	COG3977	Valine--pyruvate aminotransferase
ECB94_09080	COG0752	glycyl-tRNA synthetase alpha subunit
ECB94_09085	COG2119	membrane
ECB94_09095	COG0425	Belongs to the sulfur carrier protein TusA family
ECB94_09105	COG0583	DNA-binding transcription factor activity
ECB94_09110	COG2863	cytochrome
ECB94_09115	COG3258	Cytochrome c
ECB94_09120	COG0604	alcohol dehydrogenase
ECB94_09125	COG0183	Belongs to the thiolase family
ECB94_09135	COG1739	Uncharacterized protein family UPF0029
ECB94_09140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ECB94_09195	COG0583	DNA-binding transcription factor activity
ECB94_09200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ECB94_09205	COG2960	long-chain fatty acid transporting porin activity
ECB94_09210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECB94_09215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_09225	COG0210	DNA helicase
ECB94_09285	COG2235	arginine
ECB94_09295	COG4172	Belongs to the ABC transporter superfamily
ECB94_09300	COG0747	negative chemotaxis
ECB94_09310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECB94_09330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECB94_09340	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ECB94_09345	COG0339	signal peptide processing
ECB94_09350	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ECB94_09355	COG1522	sequence-specific DNA binding
ECB94_09360	COG0742	ribosomal rna small subunit methyltransferase
ECB94_09375	COG0589	response to stress
ECB94_09380	COG1528	Iron-storage protein
ECB94_09390	COG2081	HI0933 family
ECB94_09395	COG3681	Belongs to the UPF0597 family
ECB94_09400	COG0814	amino acid
ECB94_09415	COG0741	lytic transglycosylase activity
ECB94_09415	COG1388	LysM domain
ECB94_09435	COG1815	bacterial-type flagellum-dependent cell motility
ECB94_09440	COG1558	bacterial-type flagellum-dependent cell motility
ECB94_09445	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ECB94_09450	COG1749	Flagellar hook protein flgE
ECB94_09455	COG4787	bacterial-type flagellum-dependent cell motility
ECB94_09460	COG4786	Flagellar basal body rod
ECB94_09465	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ECB94_09470	COG1706	bacterial-type flagellum-dependent cell motility
ECB94_09480	COG4786	Flagellar basal body rod
ECB94_09480	COG1256	bacterial-type flagellum assembly
ECB94_09485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECB94_09505	COG1360	Flagellar Motor Protein
ECB94_09510	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ECB94_09515	COG1191	sigma factor activity
ECB94_09520	COG1580	Controls the rotational direction of flagella during chemotaxis
ECB94_09535	COG1516	flagellar protein fliS
ECB94_09540	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ECB94_09545	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECB94_09570	COG1987	bacterial-type flagellum assembly
ECB94_09595	COG2204	response regulator
ECB94_09610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECB94_09630	COG1322	Protein conserved in bacteria
ECB94_09635	COG2226	methyltransferase
ECB94_09660	COG0805	protein transport
ECB94_09665	COG0084	hydrolase, TatD family'
ECB94_09680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECB94_09680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECB94_09685	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ECB94_09700	COG0534	Mate efflux family protein
ECB94_09720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ECB94_09725	COG4206	TonB-dependent receptor
ECB94_09835	COG1295	ribonuclease BN
ECB94_09845	COG0456	acetyltransferase
ECB94_09860	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ECB94_09865	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ECB94_09870	COG3031	protein transport across the cell outer membrane
ECB94_09880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECB94_09885	COG1459	type II secretion system
ECB94_09890	COG2165	general secretion pathway protein
ECB94_09895	COG2165	general secretion pathway protein
ECB94_09900	COG2165	general secretion pathway protein
ECB94_09905	COG4795	General secretion pathway protein
ECB94_09910	COG3156	type II secretion system protein K
ECB94_09915	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECB94_09920	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
ECB94_09930	COG1218	3'(2'),5'-bisphosphate nucleotidase
ECB94_09935	COG0494	nUDIX hydrolase
ECB94_09940	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ECB94_09940	COG0316	Belongs to the HesB IscA family
ECB94_09960	COG2183	response to ionizing radiation
ECB94_09965	COG0189	ligase activity
ECB94_09965	COG4067	protein conserved in archaea
ECB94_09970	COG1253	flavin adenine dinucleotide binding
ECB94_09985	COG0151	Belongs to the GarS family
ECB94_09995	COG0789	Transcriptional regulator
ECB94_10000	COG3710	Transcriptional regulator
ECB94_10005	COG0531	amino acid
ECB94_10010	COG1982	Orn Lys Arg decarboxylase major
ECB94_10015	COG0840	transmembrane signaling receptor activity
ECB94_10020	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ECB94_10035	COG0439	Biotin carboxylase
ECB94_10040	COG0511	ligase activity, forming carbon-carbon bonds
ECB94_10065	COG2814	Major facilitator Superfamily
ECB94_10070	COG2205	protein histidine kinase activity
ECB94_10070	COG2198	Histidine kinase
ECB94_10070	COG0784	Response regulator, receiver
ECB94_10085	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECB94_10100	COG4232	protein-disulfide reductase activity
ECB94_10105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECB94_10110	COG1027	Aspartate ammonia-lyase
ECB94_10125	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ECB94_10130	COG1560	Kdo2-lipid A biosynthetic process
ECB94_10135	COG1560	Kdo2-lipid A biosynthetic process
ECB94_10145	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ECB94_10150	COG2003	Belongs to the UPF0758 family
ECB94_10160	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ECB94_10165	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ECB94_10170	COG2866	Carboxypeptidase
ECB94_10175	COG2205	protein histidine kinase activity
ECB94_10180	COG0745	RESPONSE REGULATOR receiver
ECB94_10185	COG3678	ATP-independent chaperone mediated protein folding
ECB94_10190	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ECB94_10200	COG0149	triose-phosphate isomerase activity
ECB94_10225	COG1494	fructose-1,6-bisphosphatase
ECB94_10245	COG4942	peptidase
ECB94_10255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECB94_10260	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ECB94_10265	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ECB94_10270	COG1045	serine acetyltransferase
ECB94_10275	COG0534	Mate efflux family protein
ECB94_10280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ECB94_10285	COG0459	protein refolding
ECB94_10300	COG1509	lysine 2,3-aminomutase activity
ECB94_10305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ECB94_10325	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ECB94_10330	COG1053	succinate dehydrogenase
ECB94_10335	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ECB94_10345	COG0471	metal ion transport
ECB94_10345	COG0490	domain, Protein
ECB94_10355	COG1162	GTPase activity
ECB94_10360	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ECB94_10415	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ECB94_10420	COG0802	atpase or kinase
ECB94_10430	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ECB94_10445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ECB94_10450	COG0330	HflC and HflK could
ECB94_10455	COG0330	HflC and HflK could
ECB94_10460	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ECB94_10465	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ECB94_10470	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
ECB94_10475	COG0557	exoribonuclease II activity
ECB94_10495	COG0545	Peptidyl-prolyl cis-trans isomerase
ECB94_10500	COG2964	Protein conserved in bacteria
ECB94_10505	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ECB94_10510	COG2923	Belongs to the DsrF TusC family
ECB94_10530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ECB94_10540	COG2906	2 iron, 2 sulfur cluster binding
ECB94_10550	COG0051	transcription antitermination factor activity, RNA binding
ECB94_10560	COG0088	Forms part of the polypeptide exit tunnel
ECB94_10580	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ECB94_10590	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ECB94_10600	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ECB94_10605	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ECB94_10630	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ECB94_10645	COG1841	ribosomal large subunit assembly
ECB94_10655	COG0201	protein transport
ECB94_10665	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ECB94_10670	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ECB94_10685	COG0203	ribosomal protein L17
ECB94_10695	COG0545	Peptidyl-prolyl cis-trans isomerase
ECB94_10705	COG2153	protein acetylation
ECB94_10715	COG1648	precorrin-2 dehydrogenase activity
ECB94_10715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ECB94_10725	COG2895	sulfate adenylyltransferase (ATP) activity
ECB94_10730	COG3273	potassium ion transport
ECB94_10730	COG0471	metal ion transport
ECB94_10735	COG0529	Catalyzes the synthesis of activated sulfate
ECB94_10770	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ECB94_10780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ECB94_10785	COG0729	surface antigen
ECB94_10805	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ECB94_10815	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ECB94_10820	COG0163	prenyltransferase activity
ECB94_10825	COG4143	(ABC) transporter
ECB94_10830	COG1178	ABC-type Fe3 transport system permease component
ECB94_10835	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ECB94_10845	COG0312	modulator of DNA gyrase
ECB94_10850	COG2239	Acts as a magnesium transporter
ECB94_10855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_10865	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_10870	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ECB94_10880	COG1137	ATPase activity
ECB94_10885	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ECB94_10895	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ECB94_10900	COG0517	IMP dehydrogenase activity
ECB94_10900	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ECB94_10910	COG1127	ABC transporter
ECB94_10915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ECB94_10920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ECB94_10925	COG2854	intermembrane phospholipid transfer
ECB94_10935	COG5007	Belongs to the BolA IbaG family
ECB94_10940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ECB94_10945	COG0204	Acyl-transferase
ECB94_10950	COG0251	oxidation-reduction process
ECB94_10955	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ECB94_10985	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ECB94_10990	COG1546	Belongs to the CinA family
ECB94_10995	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ECB94_11010	COG0527	aspartate kinase activity
ECB94_11065	COG0511	ligase activity, forming carbon-carbon bonds
ECB94_11065	COG5016	pyruvate
ECB94_11070	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ECB94_11080	COG1238	metal cluster binding
ECB94_11085	COG0612	Peptidase, M16
ECB94_11090	COG2918	glutathione biosynthetic process
ECB94_11105	COG1678	Uncharacterized ACR, COG1678
ECB94_11110	COG0189	ligase activity
ECB94_11115	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ECB94_11120	COG2356	endonuclease I
ECB94_11135	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ECB94_11140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECB94_11150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECB94_11155	COG0126	phosphoglycerate kinase activity
ECB94_11160	COG0191	fructose-bisphosphate aldolase activity
ECB94_11165	COG0668	transmembrane transport
ECB94_11175	COG1279	arginine transmembrane transporter activity
ECB94_11180	COG0583	DNA-binding transcription factor activity
ECB94_11190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ECB94_11200	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ECB94_11220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECB94_11225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECB94_11240	COG0354	folic acid binding
ECB94_11245	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ECB94_11250	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ECB94_11255	COG1595	DNA-templated transcription, initiation
ECB94_11270	COG3086	response to oxidative stress
ECB94_11275	COG0481	GTPase activity
ECB94_11280	COG0681	Belongs to the peptidase S26 family
ECB94_11285	COG0571	ribonuclease III activity
ECB94_11290	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ECB94_11310	COG4999	Histidine kinase
ECB94_11310	COG3437	response regulator, receiver
ECB94_11310	COG2205	protein histidine kinase activity
ECB94_11310	COG3850	Histidine kinase
ECB94_11315	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ECB94_11320	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ECB94_11325	COG3956	TIGRFAM MazG family protein
ECB94_11335	COG0148	phosphopyruvate hydratase activity
ECB94_11355	COG1929	Belongs to the glycerate kinase type-1 family
ECB94_11360	COG2610	gluconate transmembrane transporter activity
ECB94_11365	COG3835	regulator
ECB94_11370	COG3112	Uncharacterised protein family (UPF0231)
ECB94_11380	COG0004	ammonium transporteR
ECB94_11385	COG1840	ABC-type Fe3 transport system, periplasmic component
ECB94_11395	COG3842	ATPase activity
ECB94_11400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ECB94_11415	COG2971	BadF BadG BcrA BcrD
ECB94_11425	COG4608	Belongs to the ABC transporter superfamily
ECB94_11430	COG0444	Belongs to the ABC transporter superfamily
ECB94_11435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECB94_11445	COG0747	negative chemotaxis
ECB94_11460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECB94_11465	COG0358	DNA primase activity
ECB94_11470	COG1610	YqeY-like protein
ECB94_11475	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ECB94_11485	COG2267	carboxylic ester hydrolase activity
ECB94_11495	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ECB94_11510	COG0617	tRNA 3'-terminal CCA addition
ECB94_11515	COG3267	Type II secretory pathway component ExeA
ECB94_11515	COG3409	Peptidoglycan-binding domain 1 protein
ECB94_11530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ECB94_11545	COG0629	single-stranded DNA binding
ECB94_11550	COG2200	EAL domain
ECB94_11550	COG2199	diguanylate cyclase activity
ECB94_11575	COG3409	Peptidoglycan-binding domain 1 protein
ECB94_11575	COG3267	Type II secretory pathway component ExeA
ECB94_11585	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ECB94_11590	COG1459	type II secretion system
ECB94_11635	COG1077	Cell shape determining protein MreB Mrl
ECB94_11640	COG1792	Involved in formation and maintenance of cell shape
ECB94_11645	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ECB94_11650	COG0424	maF-like protein
ECB94_11655	COG1530	ribonuclease E activity
ECB94_11660	COG3164	Protein of unknown function
ECB94_11665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECB94_11670	COG0312	modulator of DNA gyrase
ECB94_11675	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ECB94_11680	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ECB94_11690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECB94_11695	COG0589	response to stress
ECB94_11725	COG0142	geranyltranstransferase activity
ECB94_11735	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ECB94_11740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ECB94_11745	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ECB94_11750	COG1289	transmembrane transporter activity
ECB94_11755	COG2966	Psort location CytoplasmicMembrane, score
ECB94_11775	COG2967	ApaG domain
ECB94_11785	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ECB94_11795	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECB94_11800	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ECB94_11815	COG0066	3-isopropylmalate dehydratase activity
ECB94_11825	COG0473	3-isopropylmalate dehydrogenase activity
ECB94_11855	COG0671	phosphoesterase, PA-phosphatase related
ECB94_11865	COG0583	DNA-binding transcription factor activity
ECB94_11870	COG1022	Amp-dependent synthetase and ligase
ECB94_11875	COG0739	heme binding
ECB94_11880	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ECB94_11895	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ECB94_11915	COG0848	biopolymer transport protein
ECB94_11920	COG0811	peptide transport
ECB94_11925	COG0811	peptide transport
ECB94_11940	COG4774	siderophore transport
ECB94_11945	COG4977	sequence-specific DNA binding
ECB94_11955	COG1115	amino acid carrier protein
ECB94_11965	COG0513	Belongs to the DEAD box helicase family
ECB94_11970	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ECB94_11980	COG0716	FMN binding
ECB94_11990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECB94_11995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ECB94_12005	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ECB94_12010	COG2204	response regulator
ECB94_12020	COG0667	Aldo Keto reductase
ECB94_12030	COG3066	DNA modification
ECB94_12040	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ECB94_12045	COG0730	response to heat
ECB94_12055	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ECB94_12060	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_12075	COG1283	sodium-dependent phosphate transmembrane transporter activity
ECB94_12080	COG0583	DNA-binding transcription factor activity
ECB94_12085	COG0640	Transcriptional regulator
ECB94_12095	COG0728	peptidoglycan biosynthetic process
ECB94_12100	COG0196	riboflavin kinase activity
ECB94_12110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ECB94_12115	COG1047	Peptidyl-prolyl cis-trans
ECB94_12130	COG2027	D-alanyl-D-alanine carboxypeptidase
ECB94_12135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ECB94_12140	COG1534	Rna-binding protein
ECB94_12150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ECB94_12155	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ECB94_12160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ECB94_12165	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ECB94_12180	COG0779	Required for maturation of 30S ribosomal subunits
ECB94_12185	COG0195	Participates in both transcription termination and antitermination
ECB94_12200	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ECB94_12205	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ECB94_12225	COG0534	Mate efflux family protein
ECB94_12250	COG3153	acetyltransferase
ECB94_12270	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_12320	COG0084	hydrolase, TatD family'
ECB94_12325	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ECB94_12330	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ECB94_12345	COG0813	purine-nucleoside phosphorylase activity
ECB94_12355	COG0560	Phosphoserine phosphatase
ECB94_12365	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ECB94_12370	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ECB94_12375	COG0583	DNA-binding transcription factor activity
ECB94_12380	COG5457	Domain of unknown function (DUF1127)
ECB94_12385	COG1022	Amp-dependent synthetase and ligase
ECB94_12395	COG2059	Chromate
ECB94_12400	COG0583	DNA-binding transcription factor activity
ECB94_12420	COG3250	beta-galactosidase activity
ECB94_12430	COG0534	Mate efflux family protein
ECB94_12440	COG1129	ABC transporter
ECB94_12450	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ECB94_12465	COG2017	converts alpha-aldose to the beta-anomer
ECB94_12470	COG1609	Transcriptional regulator
ECB94_12480	COG2211	Major facilitator Superfamily
ECB94_12490	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_12490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_12490	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_12495	COG2207	Transcriptional regulator
ECB94_12505	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_12515	COG0367	asparagine synthase
ECB94_12520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ECB94_12520	COG4651	solute:proton antiporter activity
ECB94_12525	COG1846	Transcriptional regulator
ECB94_12525	COG1940	carbohydrate kinase activity
ECB94_12530	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECB94_12535	COG2190	(PTS) system
ECB94_12535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_12535	COG1263	PTS System
ECB94_12540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ECB94_12545	COG0735	belongs to the Fur family
ECB94_12560	COG0716	FMN binding
ECB94_12570	COG0596	Alpha beta hydrolase
ECB94_12575	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ECB94_12580	COG0033	Phosphoglucomutase
ECB94_12585	COG0583	DNA-binding transcription factor activity
ECB94_12595	COG2363	Small membrane protein
ECB94_12605	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ECB94_12610	COG1611	Belongs to the LOG family
ECB94_12615	COG3706	GGDEF domain
ECB94_12635	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
ECB94_12640	COG1464	Belongs to the NlpA lipoprotein family
ECB94_12645	COG2011	ABC-type metal ion transport system permease component
ECB94_12650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ECB94_12655	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ECB94_12670	COG1263	PTS System
ECB94_12670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_12675	COG0366	Alpha amylase catalytic
ECB94_12695	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ECB94_12710	COG1686	Belongs to the peptidase S11 family
ECB94_12715	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ECB94_12720	COG0772	Belongs to the SEDS family
ECB94_12725	COG0768	penicillin binding
ECB94_12730	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ECB94_12735	COG0799	negative regulation of ribosome biogenesis
ECB94_12740	COG1466	dna polymerase III delta subunit
ECB94_12745	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ECB94_12750	COG0495	leucyl-tRNA aminoacylation
ECB94_12755	COG2888	peptidyl-tyrosine sulfation
ECB94_12760	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ECB94_12765	COG3115	cell septum assembly
ECB94_12785	COG0789	Transcriptional regulator
ECB94_12815	COG2608	mercury ion transmembrane transporter activity
ECB94_12815	COG2217	Heavy metal translocating P-type atpase
ECB94_12825	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ECB94_12830	COG0142	geranyltranstransferase activity
ECB94_12840	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ECB94_12860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ECB94_12865	COG0372	Belongs to the citrate synthase family
ECB94_12870	COG2009	succinate dehydrogenase
ECB94_12875	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ECB94_12880	COG1053	succinate dehydrogenase
ECB94_12890	COG0567	Dehydrogenase, E1 component
ECB94_12895	COG0508	dehydrogenase complex catalyzes the overall conversion of
ECB94_12900	COG0045	succinate-CoA ligase (ADP-forming) activity
ECB94_12910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECB94_12915	COG1121	(ABC) transporter
ECB94_12920	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ECB94_12925	COG2207	Transcriptional regulator
ECB94_12935	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ECB94_12945	COG1918	ferrous iron import across plasma membrane
ECB94_12950	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ECB94_12970	COG0018	arginyl-trna synthetase
ECB94_12975	COG3102	Protein conserved in bacteria
ECB94_12985	COG0788	formyltetrahydrofolate deformylase activity
ECB94_12995	COG1199	ATP-dependent helicase activity
ECB94_13000	COG1214	PFAM Peptidase M22, glycoprotease
ECB94_13020	COG0318	PFAM AMP-dependent synthetase and ligase
ECB94_13025	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ECB94_13030	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ECB94_13035	COG2894	cell division
ECB94_13045	COG3100	YcgL domain-containing protein
ECB94_13050	COG2951	lytic endotransglycosylase activity
ECB94_13085	COG0513	Belongs to the DEAD box helicase family
ECB94_13100	COG0330	HflC and HflK could
ECB94_13105	COG3118	belongs to the thioredoxin family
ECB94_13110	COG0300	oxidoreductase activity
ECB94_13115	COG1090	epimerase
ECB94_13140	COG0622	Phosphoesterase
ECB94_13145	COG2190	(PTS) system
ECB94_13150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECB94_13155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_13160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ECB94_13165	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ECB94_13170	COG4535	Mg2 and Co2 transporter CorC
ECB94_13175	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ECB94_13180	COG1702	phosphate starvation-inducible protein PhoH
ECB94_13195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECB94_13320	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ECB94_13325	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ECB94_13335	COG2890	protein-(glutamine-N5) methyltransferase activity
ECB94_13340	COG3094	Invasion gene expression up-regulator, SirB
ECB94_13345	COG2912	Transglutaminase-like superfamily
ECB94_13350	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ECB94_13360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ECB94_13365	COG1187	pseudouridine synthase activity
ECB94_13370	COG2840	Smr protein MutS2
ECB94_13390	COG3383	formate dehydrogenase (NAD+) activity
ECB94_13405	COG1987	bacterial-type flagellum assembly
ECB94_13415	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECB94_13425	COG1815	bacterial-type flagellum-dependent cell motility
ECB94_13430	COG1558	bacterial-type flagellum-dependent cell motility
ECB94_13435	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ECB94_13440	COG1749	Flagellar hook protein flgE
ECB94_13445	COG4786	Flagellar basal body rod
ECB94_13450	COG4786	Flagellar basal body rod
ECB94_13455	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ECB94_13460	COG1706	bacterial-type flagellum-dependent cell motility
ECB94_13470	COG4786	Flagellar basal body rod
ECB94_13470	COG1256	bacterial-type flagellum assembly
ECB94_13480	COG2885	chlorophyll binding
ECB94_13495	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ECB94_13520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECB94_13540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ECB94_13545	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ECB94_13570	COG1191	sigma factor activity
ECB94_13575	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ECB94_13580	COG1360	Flagellar Motor Protein
ECB94_13590	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ECB94_13595	COG0745	RESPONSE REGULATOR receiver
ECB94_13600	COG2205	protein histidine kinase activity
ECB94_13605	COG1653	transport
ECB94_13610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECB94_13615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECB94_13620	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ECB94_13630	COG2204	response regulator
ECB94_13650	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ECB94_13655	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ECB94_13660	COG0776	regulation of translation
ECB94_13665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECB94_13690	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ECB94_13695	COG0436	Aminotransferase
ECB94_13700	COG1169	isochorismate synthase
ECB94_13710	COG0596	Alpha beta hydrolase
ECB94_13715	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ECB94_13720	COG1441	menaquinone biosynthetic process
ECB94_13725	COG0318	PFAM AMP-dependent synthetase and ligase
ECB94_13735	COG2855	membrane
ECB94_13790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_13795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECB94_13805	COG0840	transmembrane signaling receptor activity
ECB94_13805	COG3290	protein histidine kinase activity
ECB94_13810	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ECB94_13815	COG1522	sequence-specific DNA binding
ECB94_13820	COG1454	alcohol dehydrogenase
ECB94_13830	COG1946	Acyl-CoA thioesterase
ECB94_13835	COG3126	Type III secretion system lipoprotein chaperone (YscW)
ECB94_13860	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ECB94_13930	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ECB94_13940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECB94_13945	COG5002	protein histidine kinase activity
ECB94_13945	COG3850	Histidine kinase
ECB94_13980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECB94_13990	COG0251	oxidation-reduction process
ECB94_13995	COG0076	glutamate decarboxylase activity
ECB94_14000	COG2985	domain, Protein
ECB94_14010	COG0513	Belongs to the DEAD box helicase family
ECB94_14050	COG0674	pyruvate-flavodoxin oxidoreductase activity
ECB94_14060	COG0513	Belongs to the DEAD box helicase family
ECB94_14070	COG4948	Mandelate Racemase Muconate Lactonizing
ECB94_14080	COG0583	DNA-binding transcription factor activity
ECB94_14090	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ECB94_14100	COG3706	GGDEF domain
ECB94_14105	COG1609	Transcriptional regulator
ECB94_14115	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ECB94_14120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ECB94_14125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ECB94_14140	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ECB94_14145	COG0285	dihydrofolate synthase activity
ECB94_14150	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ECB94_14155	COG1286	toxin biosynthetic process
ECB94_14160	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ECB94_14165	COG0583	DNA-binding transcription factor activity
ECB94_14175	COG0745	RESPONSE REGULATOR receiver
ECB94_14195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ECB94_14205	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ECB94_14225	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ECB94_14320	COG4695	Portal protein
ECB94_14445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECB94_14460	COG2226	methyltransferase
ECB94_14465	COG0676	glucose-6-phosphate 1-epimerase activity
ECB94_14470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ECB94_14475	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ECB94_14485	COG3139	Protein of unknown function (DUF1315)
ECB94_14490	COG0659	secondary active sulfate transmembrane transporter activity
ECB94_14495	COG1530	ribonuclease E activity
ECB94_14500	COG0564	pseudouridine synthase activity
ECB94_14505	COG0424	maF-like protein
ECB94_14510	COG1399	metal-binding, possibly nucleic acid-binding protein
ECB94_14525	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ECB94_14550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ECB94_14555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ECB94_14560	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ECB94_14565	COG0470	DNA polymerase III
ECB94_14570	COG0084	hydrolase, TatD family'
ECB94_14575	COG1263	PTS System
ECB94_14575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_14590	COG0733	neurotransmitter:sodium symporter activity
ECB94_14605	COG4667	esterase of the alpha-beta hydrolase superfamily
ECB94_14610	COG1940	carbohydrate kinase activity
ECB94_14615	COG0784	Response regulator, receiver
ECB94_14615	COG0835	chemotaxis
ECB94_14635	COG4667	esterase of the alpha-beta hydrolase superfamily
ECB94_14640	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_14645	COG0616	signal peptide processing
ECB94_14655	COG0539	negative regulation of cytoplasmic translation
ECB94_14665	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ECB94_14670	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ECB94_14675	COG0284	orotidine-5'-phosphate decarboxylase activity
ECB94_14690	COG0583	DNA-binding transcription factor activity
ECB94_14700	COG0686	Belongs to the AlaDH PNT family
ECB94_14705	COG1522	sequence-specific DNA binding
ECB94_14710	COG1674	ftsk spoiiie
ECB94_14720	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ECB94_14725	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ECB94_14730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ECB94_14740	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ECB94_14745	COG0156	8-amino-7-oxononanoate synthase activity
ECB94_14755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ECB94_14770	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_14785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ECB94_14805	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ECB94_14815	COG0482	sulfurtransferase activity
ECB94_14820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECB94_14825	COG2916	Histone family protein nucleoid-structuring protein H-NS
ECB94_14830	COG1757	Na H antiporter
ECB94_14840	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ECB94_14845	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ECB94_14850	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ECB94_14850	COG0131	Imidazoleglycerol-phosphate dehydratase
ECB94_14855	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ECB94_14860	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ECB94_14870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ECB94_14870	COG0140	phosphoribosyl-ATP diphosphatase activity
ECB94_14880	COG0463	Glycosyl transferase, family 2
ECB94_14880	COG1216	Glycosyl transferase, family 2
ECB94_14895	COG2719	SpoVR family
ECB94_14900	COG2718	Belongs to the UPF0229 family
ECB94_14905	COG2766	serine protein kinase
ECB94_14915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECB94_14920	COG0840	transmembrane signaling receptor activity
ECB94_14930	COG1882	Formate acetyltransferase
ECB94_14950	COG4215	(ABC) transporter
ECB94_14955	COG4160	amino acid transport
ECB94_14960	COG0708	Exodeoxyribonuclease III
ECB94_14965	COG0840	transmembrane signaling receptor activity
ECB94_14980	COG0189	ligase activity
ECB94_14980	COG4067	protein conserved in archaea
ECB94_14995	COG1801	Protein of unknown function DUF72
ECB94_15005	COG0217	transcriptional regulatory protein
ECB94_15010	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ECB94_15020	COG0632	four-way junction helicase activity
ECB94_15025	COG2255	four-way junction helicase activity
ECB94_15030	COG1271	oxidase subunit
ECB94_15035	COG1294	oxidase, subunit
ECB94_15040	COG4890	Cyd operon protein YbgT
ECB94_15050	COG0824	Thioesterase
ECB94_15055	COG0811	peptide transport
ECB94_15075	COG2885	chlorophyll binding
ECB94_15080	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ECB94_15090	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ECB94_15115	COG5002	protein histidine kinase activity
ECB94_15115	COG0784	Response regulator, receiver
ECB94_15130	COG0582	viral genome integration into host DNA
ECB94_15165	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ECB94_15170	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ECB94_15175	COG0732	type I restriction modification DNA specificity domain
ECB94_15205	COG1401	restriction endodeoxyribonuclease activity
ECB94_15225	COG0019	diaminopimelate decarboxylase activity
ECB94_15230	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_15235	COG3842	ATPase activity
ECB94_15245	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECB94_15250	COG1177	transmembrane transport
ECB94_15255	COG3700	Belongs to the class B bacterial acid phosphatase family
ECB94_15270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECB94_15280	COG1126	abc transporter atp-binding protein
ECB94_15285	COG0765	amino acid transport
ECB94_15290	COG0765	amino acid transport
ECB94_15305	COG0318	PFAM AMP-dependent synthetase and ligase
ECB94_15325	COG4191	Histidine kinase
ECB94_15345	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ECB94_15350	COG3639	organic phosphonate transmembrane transporter activity
ECB94_15355	COG3639	organic phosphonate transmembrane transporter activity
ECB94_15365	COG1349	DNA-binding transcription factor activity
ECB94_15370	COG0738	Major facilitator superfamily
ECB94_15375	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
ECB94_15380	COG1070	Carbohydrate kinase
ECB94_15385	COG4154	Belongs to the RbsD FucU family
ECB94_15390	COG0235	Class ii aldolase
ECB94_15395	COG1454	alcohol dehydrogenase
ECB94_15410	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_15420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECB94_15435	COG2188	Transcriptional regulator
ECB94_15440	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ECB94_15460	COG3457	Alanine racemase
ECB94_15465	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ECB94_15470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ECB94_15475	COG4628	conserved protein (DUF2132)
ECB94_15480	COG0724	RNA recognition motif
ECB94_15485	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECB94_15490	COG1609	Transcriptional regulator
ECB94_15500	COG2211	Major facilitator Superfamily
ECB94_15510	COG0583	DNA-binding transcription factor activity
ECB94_15515	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ECB94_15525	COG2350	Protein conserved in bacteria
ECB94_15530	COG1607	acyl-coa hydrolase
ECB94_15545	COG1301	dicarboxylic acid transport
ECB94_15560	COG0135	phosphoribosylanthranilate isomerase activity
ECB94_15560	COG0134	indole-3-glycerol-phosphate synthase activity
ECB94_15565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ECB94_15570	COG0512	Glutamine amidotransferase of anthranilate synthase
ECB94_15575	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ECB94_15580	COG0613	PHP domain protein
ECB94_15585	COG0009	L-threonylcarbamoyladenylate synthase
ECB94_15590	COG1187	pseudouridine synthase activity
ECB94_15595	COG4172	Belongs to the ABC transporter superfamily
ECB94_15605	COG4171	peptide transport system, permease
ECB94_15610	COG4168	peptide transport system, permease
ECB94_15620	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ECB94_15625	COG1842	Phage shock protein A
ECB94_15640	COG0583	DNA-binding transcription factor activity
ECB94_15645	COG1486	melibiose metabolic process
ECB94_15670	COG0519	Catalyzes the synthesis of GMP from XMP
ECB94_15715	COG0641	radical SAM
ECB94_15730	COG3119	arylsulfatase activity
ECB94_15735	COG1309	transcriptional regulator
ECB94_15765	COG1278	Cold shock
ECB94_15780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ECB94_15785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ECB94_15810	COG0626	cystathionine gamma-synthase activity
ECB94_15820	COG0733	neurotransmitter:sodium symporter activity
ECB94_15825	COG0564	pseudouridine synthase activity
ECB94_15830	COG0116	Belongs to the methyltransferase superfamily
ECB94_15830	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ECB94_15840	COG3313	Fe-S protein
ECB94_15845	COG3437	response regulator, receiver
ECB94_15850	COG3706	GGDEF domain
ECB94_15865	COG2233	PERMEase
ECB94_15875	COG3842	ATPase activity
ECB94_15880	COG0395	ABC-type sugar transport system, permease component
ECB94_15885	COG1175	transmembrane transport
ECB94_15895	COG0584	glycerophosphoryl diester phosphodiesterase
ECB94_15900	COG1349	DNA-binding transcription factor activity
ECB94_15905	COG3437	response regulator, receiver
ECB94_15905	COG0784	Response regulator, receiver
ECB94_15910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECB94_15910	COG1522	sequence-specific DNA binding
ECB94_15915	COG2313	pseudouridylate synthase activity
ECB94_15930	COG1342	Belongs to the UPF0251 family
ECB94_15940	COG3437	response regulator, receiver
ECB94_15945	COG0784	Response regulator, receiver
ECB94_15945	COG2205	protein histidine kinase activity
ECB94_15945	COG5002	protein histidine kinase activity
ECB94_15950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECB94_15955	COG1349	DNA-binding transcription factor activity
ECB94_15995	COG1396	sequence-specific DNA binding
ECB94_16000	COG3135	benzoate transporter
ECB94_16005	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ECB94_16025	COG3283	Transcriptional regulator of aromatic amino acids metabolism
ECB94_16030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECB94_16050	COG0471	metal ion transport
ECB94_16055	COG4191	Histidine kinase
ECB94_16055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECB94_16065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ECB94_16070	COG2111	Na H antiporter
ECB94_16070	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ECB94_16090	COG2212	antiporter activity
ECB94_16095	COG1320	monovalent cation:proton antiporter activity
ECB94_16105	COG1901	pseudouridine methyltransferase
ECB94_16125	COG0110	maltose O-acetyltransferase activity
ECB94_16130	COG1609	Transcriptional regulator
ECB94_16135	COG1840	ABC-type Fe3 transport system, periplasmic component
ECB94_16140	COG1175	transmembrane transport
ECB94_16145	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ECB94_16155	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ECB94_16165	COG4221	oxidoreductase activity
ECB94_16175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECB94_16180	COG0628	permease
ECB94_16225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ECB94_16240	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ECB94_16265	COG4139	cobalamin transport
ECB94_16280	COG0659	secondary active sulfate transmembrane transporter activity
ECB94_16330	COG0583	DNA-binding transcription factor activity
ECB94_16345	COG0697	spore germination
ECB94_16350	COG1846	Transcriptional regulator
ECB94_16360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ECB94_16365	COG3960	tartronate-semialdehyde synthase activity
ECB94_16370	COG3622	Belongs to the hyi family
ECB94_16375	COG2084	Dehydrogenase
ECB94_16400	COG0346	lactoylglutathione lyase activity
ECB94_16415	COG2252	PERMEase
ECB94_16435	COG4266	Belongs to the allantoicase family
ECB94_16440	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ECB94_16455	COG4221	oxidoreductase activity
ECB94_16495	COG0583	DNA-binding transcription factor activity
ECB94_16530	COG0114	fumarate hydratase activity
ECB94_16535	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_16540	COG0583	DNA-binding transcription factor activity
ECB94_16545	COG0667	Aldo Keto reductase
ECB94_16550	COG0006	proline dipeptidase activity
ECB94_16555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECB94_16560	COG1733	regulation of RNA biosynthetic process
ECB94_16570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ECB94_16610	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_16625	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ECB94_16640	COG0402	S-adenosylhomocysteine deaminase activity
ECB94_16650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECB94_16660	COG2186	Transcriptional regulator
ECB94_16665	COG0861	Integral membrane protein TerC family
ECB94_16685	COG0183	Belongs to the thiolase family
ECB94_16690	COG1082	Xylose isomerase domain protein TIM barrel
ECB94_16700	COG0583	DNA-binding transcription factor activity
ECB94_16705	COG0477	Major facilitator Superfamily
ECB94_16705	COG2814	Major facilitator Superfamily
ECB94_16715	COG3962	Belongs to the TPP enzyme family
ECB94_16720	COG0673	inositol 2-dehydrogenase activity
ECB94_16725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECB94_16745	COG1082	Xylose isomerase domain protein TIM barrel
ECB94_16750	COG3718	enzyme involved in inositol metabolism
ECB94_16755	COG0673	inositol 2-dehydrogenase activity
ECB94_16765	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECB94_16770	COG1129	ABC transporter
ECB94_16800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ECB94_16820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_16840	COG2208	phosphoserine phosphatase activity
ECB94_16845	COG1366	Belongs to the anti-sigma-factor antagonist family
ECB94_16850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ECB94_16860	COG3250	beta-galactosidase activity
ECB94_16895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ECB94_16905	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ECB94_17015	COG5507	3-demethylubiquinone-9 3-methyltransferase
ECB94_17095	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_17125	COG0405	Gamma-glutamyltransferase
ECB94_17140	COG1132	(ABC) transporter
ECB94_17160	COG5002	protein histidine kinase activity
ECB94_17160	COG2205	protein histidine kinase activity
ECB94_17160	COG0784	Response regulator, receiver
ECB94_17175	COG0183	Belongs to the thiolase family
ECB94_17185	COG3243	poly(R)-hydroxyalkanoic acid synthase
ECB94_17195	COG1301	dicarboxylic acid transport
ECB94_17210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_17225	COG3290	protein histidine kinase activity
ECB94_17230	COG4565	transcriptional regulatory protein
ECB94_17255	COG2186	Transcriptional regulator
ECB94_17260	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ECB94_17265	COG0372	Belongs to the citrate synthase family
ECB94_17275	COG2828	Protein conserved in bacteria
ECB94_17300	COG1115	amino acid carrier protein
ECB94_17340	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ECB94_17345	COG0295	cytidine deaminase activity
ECB94_17350	COG1346	cytolysis
ECB94_17360	COG2925	Exonuclease
ECB94_17385	COG0456	acetyltransferase
ECB94_17400	COG0384	phenazine biosynthesis protein PhzF
ECB94_17440	COG1566	PFAM secretion protein HlyD family protein
ECB94_17450	COG0628	permease
ECB94_17485	COG0443	Heat shock 70 kDa protein
ECB94_17500	COG3706	GGDEF domain
ECB94_17530	COG1643	Atp-dependent helicase
ECB94_17540	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ECB94_17560	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ECB94_17565	COG1280	lysine exporter protein (LysE YggA)
ECB94_17585	COG3842	ATPase activity
ECB94_17590	COG4662	Binding-protein-dependent transport system inner membrane component
ECB94_17600	COG2204	response regulator
ECB94_17605	COG3852	Histidine kinase
ECB94_17630	COG2910	NAD(P)H-binding
ECB94_17635	COG0583	DNA-binding transcription factor activity
ECB94_17640	COG1472	Belongs to the glycosyl hydrolase 3 family
ECB94_17645	COG4608	Belongs to the ABC transporter superfamily
ECB94_17650	COG0444	Belongs to the ABC transporter superfamily
ECB94_17655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ECB94_17670	COG1132	(ABC) transporter
ECB94_17690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ECB94_17695	COG1999	signal sequence binding
ECB94_17710	COG3005	denitrification pathway
ECB94_17725	COG0583	DNA-binding transcription factor activity
ECB94_17735	COG0435	Glutathione S-transferase
ECB94_17740	COG0435	Glutathione S-transferase
ECB94_17745	COG2259	Doxx family
ECB94_17750	COG0583	DNA-binding transcription factor activity
ECB94_17765	COG3469	chitinase activity
ECB94_17770	COG1522	sequence-specific DNA binding
ECB94_17785	COG1131	(ABC) transporter
ECB94_17790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECB94_17800	COG1881	PFAM PEBP family protein
ECB94_17810	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ECB94_17845	COG4533	DNA binding
ECB94_17850	COG2723	6-phospho-beta-galactosidase activity
ECB94_17855	COG4409	exo-alpha-(2->6)-sialidase activity
ECB94_17865	COG1609	Transcriptional regulator
ECB94_17870	COG2723	6-phospho-beta-galactosidase activity
ECB94_17885	COG3842	ATPase activity
ECB94_17890	COG1175	transmembrane transport
ECB94_17895	COG0395	ABC-type sugar transport system, permease component
ECB94_17900	COG3291	Pkd domain containing protein
ECB94_17905	COG1609	Transcriptional regulator
ECB94_17910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_17910	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_17915	COG1105	Belongs to the carbohydrate kinase PfkB family
ECB94_17920	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ECB94_17920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_17920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_17940	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ECB94_17970	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ECB94_17980	COG2211	Major facilitator Superfamily
ECB94_18010	COG0583	DNA-binding transcription factor activity
ECB94_18020	COG0577	efflux transmembrane transporter activity
ECB94_18020	COG1136	(ABC) transporter
ECB94_18025	COG1136	(ABC) transporter
ECB94_18025	COG0577	efflux transmembrane transporter activity
ECB94_18030	COG0577	efflux transmembrane transporter activity
ECB94_18045	COG0513	Belongs to the DEAD box helicase family
ECB94_18065	COG2188	Transcriptional regulator
ECB94_18075	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_18075	COG1263	PTS System
ECB94_18080	COG0583	DNA-binding transcription factor activity
ECB94_18105	COG1566	PFAM secretion protein HlyD family protein
ECB94_18115	COG0583	DNA-binding transcription factor activity
ECB94_18145	COG1902	pentaerythritol trinitrate reductase activity
ECB94_18150	COG0346	lactoylglutathione lyase activity
ECB94_18155	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ECB94_18165	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ECB94_18170	COG2207	Transcriptional regulator
ECB94_18175	COG0210	DNA helicase
ECB94_18180	COG0069	glutamate synthase activity
ECB94_18180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ECB94_18185	COG2188	Transcriptional regulator
ECB94_18190	COG2723	6-phospho-beta-galactosidase activity
ECB94_18195	COG2197	response regulator
ECB94_18200	COG3850	Histidine kinase
ECB94_18215	COG0243	molybdopterin cofactor binding
ECB94_18235	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ECB94_18240	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECB94_18245	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECB94_18270	COG4251	negative regulation of phosphorylation
ECB94_18270	COG3706	GGDEF domain
ECB94_18270	COG2203	Gaf domain
ECB94_18270	COG5001	Diguanylate cyclase
ECB94_18330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ECB94_18335	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ECB94_18335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ECB94_18340	COG0583	DNA-binding transcription factor activity
ECB94_18350	COG2824	Alkylphosphonate utilization operon protein PhnA
ECB94_18365	COG2514	catechol 2,3-dioxygenase activity
ECB94_18370	COG0748	coenzyme F420 binding
ECB94_18375	COG3721	Heme iron utilization protein
ECB94_18385	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ECB94_18390	COG0811	peptide transport
ECB94_18395	COG0848	biopolymer transport protein
ECB94_18405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECB94_18410	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ECB94_18445	COG0583	DNA-binding transcription factor activity
ECB94_18450	COG1620	l-lactate permease
ECB94_18460	COG1139	Iron-sulfur cluster binding protein
ECB94_18475	COG3706	GGDEF domain
ECB94_18490	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ECB94_18495	COG2723	6-phospho-beta-galactosidase activity
ECB94_18500	COG1940	carbohydrate kinase activity
ECB94_18505	COG1940	carbohydrate kinase activity
ECB94_18510	COG1741	Belongs to the pirin family
ECB94_18520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ECB94_18540	COG0784	Response regulator, receiver
ECB94_18540	COG5002	protein histidine kinase activity
ECB94_18545	COG0840	transmembrane signaling receptor activity
ECB94_18565	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ECB94_18570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECB94_18575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECB94_18580	COG1120	ATPase activity
ECB94_18590	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ECB94_18625	COG1126	abc transporter atp-binding protein
ECB94_18630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECB94_18635	COG4215	(ABC) transporter
ECB94_18640	COG4160	amino acid transport
ECB94_18655	COG2130	NADP-dependent
ECB94_18660	COG1309	transcriptional regulator
ECB94_18675	COG0251	oxidation-reduction process
ECB94_18690	COG2223	nitrite transmembrane transporter activity
ECB94_18700	COG2376	Dihydroxyacetone kinase
ECB94_18705	COG1461	Dihydroxyacetone kinase
ECB94_18715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECB94_18725	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ECB94_18740	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ECB94_18745	COG0804	urea catabolic process
ECB94_18750	COG0832	Belongs to the urease beta subunit family
ECB94_18755	COG0831	urea catabolic process
ECB94_18780	COG0559	Belongs to the binding-protein-dependent transport system permease family
ECB94_18790	COG0534	Mate efflux family protein
ECB94_18820	COG1560	Kdo2-lipid A biosynthetic process
ECB94_18855	COG5001	Diguanylate cyclase
ECB94_18855	COG5002	protein histidine kinase activity
ECB94_18860	COG2205	protein histidine kinase activity
ECB94_18860	COG0784	Response regulator, receiver
ECB94_18870	COG3539	Fimbrial protein
ECB94_18875	COG3188	usher protein
ECB94_18920	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ECB94_18935	COG0633	Ferredoxin
ECB94_18935	COG3217	Mosc domain protein beta barrel domain protein
ECB94_18975	COG2190	(PTS) system
ECB94_18975	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_18975	COG1263	PTS System
ECB94_18980	COG1454	alcohol dehydrogenase
ECB94_19010	COG2154	pterin-4-alpha-carbinolamine dehydratase
ECB94_19015	COG3186	Phenylalanine-4-hydroxylase
ECB94_19020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ECB94_19030	COG0668	transmembrane transport
ECB94_19035	COG0583	DNA-binding transcription factor activity
ECB94_19040	COG0387	Pfam Sodium calcium exchanger
ECB94_19045	COG2239	Acts as a magnesium transporter
ECB94_19065	COG0463	Glycosyl transferase, family 2
ECB94_19070	COG0586	Pfam SNARE associated Golgi protein
ECB94_19115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ECB94_19120	COG0129	dihydroxy-acid dehydratase activity
ECB94_19125	COG4948	Mandelate Racemase Muconate Lactonizing
ECB94_19130	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ECB94_19140	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECB94_19145	COG0800	Aldolase
ECB94_19150	COG3734	2-keto-3-deoxy-galactonokinase
ECB94_19155	COG2186	Transcriptional regulator
ECB94_19175	COG3136	membrane protein required for alginate biosynthesis
ECB94_19185	COG1609	Transcriptional regulator
ECB94_19195	COG3842	ATPase activity
ECB94_19200	COG0395	ABC-type sugar transport system, permease component
ECB94_19205	COG1175	transmembrane transport
ECB94_19215	COG0366	Alpha amylase catalytic
ECB94_19220	COG0438	transferase activity, transferring glycosyl groups
ECB94_19225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ECB94_19235	COG1175	transmembrane transport
ECB94_19240	COG4208	sulfate ABC transporter
ECB94_19250	COG1940	carbohydrate kinase activity
ECB94_19260	COG0438	transferase activity, transferring glycosyl groups
ECB94_19270	COG4604	ABC transporter, ATP-binding protein
ECB94_19275	COG4605	iron ion homeostasis
ECB94_19280	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ECB94_19285	COG4607	ABC-type enterochelin transport system periplasmic component
ECB94_19290	COG2188	Transcriptional regulator
ECB94_19295	COG2354	Protein conserved in bacteria
ECB94_19315	COG2814	Major facilitator Superfamily
ECB94_19335	COG0488	(ABC) transporter
ECB94_19340	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECB94_19345	COG1595	DNA-templated transcription, initiation
ECB94_19365	COG0739	heme binding
ECB94_19395	COG1621	beta-fructofuranosidase activity
ECB94_19400	COG1263	PTS System
ECB94_19400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_19405	COG2188	Transcriptional regulator
ECB94_19415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECB94_19430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ECB94_19435	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_19440	COG2957	Belongs to the agmatine deiminase family
ECB94_19450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ECB94_19455	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_19460	COG1396	sequence-specific DNA binding
ECB94_19460	COG1917	Cupin 2, conserved barrel domain protein
ECB94_19465	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ECB94_19470	COG0174	glutamine synthetase
ECB94_19475	COG1757	Na H antiporter
ECB94_19480	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ECB94_19495	COG1247	-acetyltransferase
ECB94_19530	COG4264	IucA IucC family
ECB94_19540	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ECB94_19545	COG1120	ATPase activity
ECB94_19570	COG0668	transmembrane transport
ECB94_19585	COG1454	alcohol dehydrogenase
ECB94_19615	COG0583	DNA-binding transcription factor activity
ECB94_19620	COG1846	Transcriptional regulator
ECB94_19625	COG1764	response to oxidative stress
ECB94_19630	COG0363	glucosamine-6-phosphate deaminase activity
ECB94_19635	COG0514	ATP-dependent DNA helicase (RecQ)
ECB94_19675	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ECB94_19680	COG1228	amidohydrolase
ECB94_19735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ECB94_19740	COG1349	DNA-binding transcription factor activity
ECB94_19745	COG3722	fumarate hydratase activity
ECB94_19750	COG0246	Mannitol dehydrogenase
ECB94_19755	COG2213	PTS system mannitol-specific
ECB94_19755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_19760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECB94_19770	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ECB94_19800	COG4533	DNA binding
ECB94_19810	COG4221	oxidoreductase activity
ECB94_19830	COG2186	Transcriptional regulator
ECB94_19835	COG3250	beta-galactosidase activity
ECB94_19845	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECB94_19860	COG0246	Mannitol dehydrogenase
ECB94_19865	COG1904	glucuronate isomerase
ECB94_19870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECB94_19875	COG0800	Aldolase
ECB94_19910	COG3842	ATPase activity
ECB94_19915	COG0395	ABC-type sugar transport system, permease component
ECB94_19920	COG1175	transmembrane transport
ECB94_19925	COG1653	transport
ECB94_19930	COG1609	Transcriptional regulator
ECB94_19940	COG1438	arginine binding
ECB94_19945	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECB94_19960	COG1288	antiporter activity
ECB94_19980	COG1418	mRNA catabolic process
ECB94_19985	COG0384	phenazine biosynthesis protein PhzF
ECB94_20000	COG3046	protein related to deoxyribodipyrimidine photolyase
ECB94_20005	COG0415	Belongs to the DNA photolyase family
ECB94_20015	COG3706	GGDEF domain
ECB94_20020	COG3437	response regulator, receiver
ECB94_20025	COG3437	response regulator, receiver
ECB94_20045	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ECB94_20055	COG3706	GGDEF domain
ECB94_20065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECB94_20070	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ECB94_20075	COG2176	DNA-directed DNA polymerase activity
ECB94_20080	COG0517	IMP dehydrogenase activity
ECB94_20085	COG2186	Transcriptional regulator
ECB94_20090	COG2186	Transcriptional regulator
ECB94_20105	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_20150	COG1917	Cupin 2, conserved barrel domain protein
ECB94_20160	COG0800	Aldolase
ECB94_20165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECB94_20180	COG2755	lipolytic protein G-D-S-L family
ECB94_20180	COG0657	acetylesterase activity
ECB94_20190	COG1917	Cupin 2, conserved barrel domain protein
ECB94_20200	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_20220	COG0840	transmembrane signaling receptor activity
ECB94_20240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECB94_20245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECB94_20250	COG1904	glucuronate isomerase
ECB94_20260	COG1902	pentaerythritol trinitrate reductase activity
ECB94_20265	COG0583	DNA-binding transcription factor activity
ECB94_20275	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ECB94_20305	COG1309	transcriptional regulator
ECB94_20310	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ECB94_20315	COG1640	4-alpha-glucanotransferase
ECB94_20320	COG0058	SHG alpha-glucan phosphorylase activity
ECB94_20345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_20380	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECB94_20385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECB94_20390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ECB94_20405	COG2855	membrane
ECB94_20430	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECB94_20435	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ECB94_20440	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECB94_20450	COG0561	phosphatase activity
ECB94_20465	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ECB94_20470	COG1414	Transcriptional regulator
ECB94_20475	COG3623	hexulose-6-phosphate isomerase
ECB94_20490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECB94_20495	COG0730	response to heat
ECB94_20500	COG0280	phosphate acetyltransferase
ECB94_20505	COG1414	Transcriptional regulator
ECB94_20510	COG1357	PFAM Pentapeptide repeats (8 copies)
ECB94_20515	COG3639	organic phosphonate transmembrane transporter activity
ECB94_20540	COG2814	Major facilitator Superfamily
ECB94_20555	COG4533	DNA binding
ECB94_20560	COG0110	maltose O-acetyltransferase activity
ECB94_20580	COG0583	DNA-binding transcription factor activity
ECB94_20590	COG0672	)-iron permease
ECB94_20615	COG1136	(ABC) transporter
ECB94_20615	COG0577	efflux transmembrane transporter activity
ECB94_20620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ECB94_20630	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ECB94_20645	COG5380	lipid catabolic process
ECB94_20650	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ECB94_20655	COG3568	Endonuclease Exonuclease Phosphatase
ECB94_20670	COG0450	alkyl hydroperoxide reductase
ECB94_20685	COG0583	DNA-binding transcription factor activity
ECB94_20705	COG0450	alkyl hydroperoxide reductase
ECB94_20710	COG0519	Catalyzes the synthesis of GMP from XMP
ECB94_20715	COG2205	protein histidine kinase activity
ECB94_20730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ECB94_20740	COG3247	response to pH
ECB94_20745	COG0583	DNA-binding transcription factor activity
ECB94_20765	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ECB94_20770	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ECB94_20775	COG3454	Phosphonate metabolism
ECB94_20780	COG4778	phosphonate C-P lyase system protein PhnL
ECB94_20785	COG4107	phosphonate C-P lyase system protein PhnK
ECB94_20790	COG3627	carbon phosphorus lyase activity
ECB94_20795	COG3626	phosphonate metabolism
ECB94_20800	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ECB94_20805	COG3624	Phosphonate C-P lyase system protein PhnG
ECB94_20810	COG2188	Transcriptional regulator
ECB94_20830	COG5002	protein histidine kinase activity
ECB94_20830	COG0784	Response regulator, receiver
ECB94_20830	COG2205	protein histidine kinase activity
ECB94_20835	COG4399	Belongs to the UPF0754 family
ECB94_20855	COG0583	DNA-binding transcription factor activity
ECB94_20865	COG0443	Heat shock 70 kDa protein
ECB94_20870	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ECB94_20880	COG3623	hexulose-6-phosphate isomerase
ECB94_20885	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ECB94_20890	COG0561	phosphatase activity
ECB94_20925	COG0561	phosphatase activity
ECB94_20935	COG2188	Transcriptional regulator
ECB94_20940	COG1486	melibiose metabolic process
ECB94_20945	COG1263	PTS System
ECB94_20945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_20970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ECB94_20995	COG1444	tRNA N-acetyltransferase activity
ECB94_21040	COG2084	Dehydrogenase
ECB94_21055	COG0786	glutamate:sodium symporter activity
ECB94_21085	COG0259	pyridoxamine-phosphate oxidase activity
ECB94_21120	COG3842	ATPase activity
ECB94_21135	COG0387	Pfam Sodium calcium exchanger
ECB94_21140	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECB94_21145	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ECB94_21155	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECB94_21165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECB94_21170	COG2723	6-phospho-beta-galactosidase activity
ECB94_21175	COG1609	Transcriptional regulator
ECB94_21185	COG3265	gluconokinase activity
ECB94_21190	COG2723	6-phospho-beta-galactosidase activity
ECB94_21205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ECB94_21210	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ECB94_21215	COG4890	Cyd operon protein YbgT
ECB94_21220	COG1294	oxidase, subunit
ECB94_21225	COG1271	oxidase subunit
ECB94_21240	COG3220	belongs to the UPF0276 family
ECB94_21270	COG3716	PTS system mannose fructose sorbose family IID component
ECB94_21280	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_21285	COG2222	sugar isomerase
ECB94_21295	COG1349	DNA-binding transcription factor activity
ECB94_21305	COG1349	DNA-binding transcription factor activity
ECB94_21320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_21335	COG1522	sequence-specific DNA binding
ECB94_21345	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ECB94_21355	COG1162	GTPase activity
ECB94_21395	COG1538	Outer membrane efflux protein
ECB94_21415	COG3710	Transcriptional regulator
ECB94_21430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_21435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECB94_21465	COG3710	Transcriptional regulator
ECB94_21490	COG2985	domain, Protein
ECB94_21495	COG0076	glutamate decarboxylase activity
ECB94_21505	COG1566	PFAM secretion protein HlyD family protein
ECB94_21545	COG1999	signal sequence binding
ECB94_21560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ECB94_21570	COG0625	glutathione transferase activity
ECB94_21580	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ECB94_21590	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECB94_21600	COG1132	(ABC) transporter
ECB94_21610	COG4628	conserved protein (DUF2132)
ECB94_21630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECB94_21650	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_21660	COG0642	Histidine kinase
ECB94_21665	COG0745	RESPONSE REGULATOR receiver
ECB94_21690	COG5002	protein histidine kinase activity
ECB94_21725	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ECB94_21735	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ECB94_21745	COG0583	DNA-binding transcription factor activity
ECB94_21760	COG0534	Mate efflux family protein
ECB94_21765	COG0625	glutathione transferase activity
ECB94_21775	COG0783	Belongs to the Dps family
ECB94_21795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ECB94_21800	COG0531	amino acid
ECB94_21805	COG2731	YhcH YjgK YiaL family protein
ECB94_21810	COG3250	beta-galactosidase activity
ECB94_21815	COG1609	Transcriptional regulator
ECB94_21845	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ECB94_21885	COG0471	metal ion transport
ECB94_21895	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ECB94_21910	COG0583	DNA-binding transcription factor activity
ECB94_21945	COG0583	DNA-binding transcription factor activity
ECB94_21950	COG0842	Transport permease protein
ECB94_21955	COG1131	(ABC) transporter
ECB94_21965	COG0739	heme binding
ECB94_21975	COG0437	4 iron, 4 sulfur cluster binding
ECB94_21980	COG0348	domain, Protein
ECB94_22010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECB94_22015	COG0251	oxidation-reduction process
ECB94_22020	COG0006	proline dipeptidase activity
ECB94_22040	COG2964	Protein conserved in bacteria
ECB94_22045	COG0006	proline dipeptidase activity
ECB94_22055	COG1473	amidohydrolase
ECB94_22060	COG2873	o-acetylhomoserine
ECB94_22065	COG1522	sequence-specific DNA binding
ECB94_22075	COG3437	response regulator, receiver
ECB94_22080	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ECB94_22095	COG0583	DNA-binding transcription factor activity
ECB94_22100	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ECB94_22100	COG0517	IMP dehydrogenase activity
ECB94_22105	COG3730	PTS system glucitol sorbitol-specific
ECB94_22120	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_22130	COG1349	DNA-binding transcription factor activity
ECB94_22135	COG3730	PTS system glucitol sorbitol-specific
ECB94_22160	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ECB94_22165	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ECB94_22170	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
ECB94_22175	COG1737	Transcriptional regulator
ECB94_22180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ECB94_22185	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ECB94_22190	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECB94_22195	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECB94_22200	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ECB94_22205	COG1940	carbohydrate kinase activity
ECB94_22210	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ECB94_22225	COG1234	tRNA 3'-trailer cleavage
ECB94_22300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_22305	COG4771	TonB-dependent receptor
ECB94_22310	COG0583	DNA-binding transcription factor activity
ECB94_22320	COG2814	Major facilitator Superfamily
ECB94_22325	COG1309	transcriptional regulator
ECB94_22330	COG0589	response to stress
ECB94_22345	COG0625	glutathione transferase activity
ECB94_22350	COG0583	DNA-binding transcription factor activity
ECB94_22390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_22390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_22390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_22395	COG2188	Transcriptional regulator
ECB94_22400	COG1882	Formate acetyltransferase
ECB94_22405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECB94_22415	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ECB94_22420	COG0612	Peptidase, M16
ECB94_22425	COG0071	Belongs to the small heat shock protein (HSP20) family
ECB94_22430	COG0443	Heat shock 70 kDa protein
ECB94_22435	COG0484	heat shock protein binding
ECB94_22445	COG0786	glutamate:sodium symporter activity
ECB94_22450	COG0668	transmembrane transport
ECB94_22455	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ECB94_22460	COG0243	molybdopterin cofactor binding
ECB94_22465	COG3005	denitrification pathway
ECB94_22470	COG1566	PFAM secretion protein HlyD family protein
ECB94_22490	COG0813	purine-nucleoside phosphorylase activity
ECB94_22495	COG3272	Protein of unknown function (DUF1722)
ECB94_22500	COG0789	Transcriptional regulator
ECB94_22505	COG0415	Belongs to the DNA photolyase family
ECB94_22510	COG1388	LysM domain
ECB94_22510	COG1376	ErfK ybiS ycfS ynhG family protein
ECB94_22520	COG0513	Belongs to the DEAD box helicase family
ECB94_22525	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ECB94_22530	COG0573	inorganic phosphate transmembrane transporter activity
ECB94_22535	COG0581	inorganic phosphate transmembrane transporter activity
ECB94_22540	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ECB94_22555	COG1011	Hydrolase
ECB94_22565	COG3278	Belongs to the heme-copper respiratory oxidase family
ECB94_22590	COG3604	Transcriptional regulator
ECB94_22605	COG0446	pyridine nucleotide-disulphide oxidoreductase
ECB94_22610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECB94_22665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECB94_22685	COG0300	oxidoreductase activity
ECB94_22695	COG0383	alpha-mannosidase activity
ECB94_22700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_22700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_22700	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_22705	COG2188	Transcriptional regulator
ECB94_22720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ECB94_22725	COG1840	ABC-type Fe3 transport system, periplasmic component
ECB94_22730	COG3842	ATPase activity
ECB94_22765	COG2814	Major facilitator Superfamily
ECB94_22770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ECB94_22795	COG0753	catalase activity
ECB94_22805	COG2211	Major facilitator Superfamily
ECB94_22810	COG1486	melibiose metabolic process
ECB94_22815	COG2169	Transcriptional regulator
ECB94_22825	COG0402	S-adenosylhomocysteine deaminase activity
ECB94_22835	COG0431	NADPH-dependent FMN reductase
ECB94_22835	COG1053	succinate dehydrogenase
ECB94_22835	COG3976	FMN-binding domain protein
ECB94_22845	COG1902	pentaerythritol trinitrate reductase activity
ECB94_22855	COG4172	Belongs to the ABC transporter superfamily
ECB94_22860	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ECB94_22865	COG2988	succinylglutamate desuccinylase activity
ECB94_22870	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ECB94_22880	COG0523	cobalamin synthesis protein
ECB94_22890	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ECB94_22905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ECB94_22910	COG1121	(ABC) transporter
ECB94_22920	COG3153	acetyltransferase
ECB94_22930	COG0583	DNA-binding transcription factor activity
ECB94_22935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_22940	COG3037	sugar-specific permease SgaT UlaA
ECB94_22970	COG3023	N-Acetylmuramoyl-L-alanine amidase
ECB94_22990	COG1349	DNA-binding transcription factor activity
ECB94_23000	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECB94_23010	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ECB94_23015	COG1834	amidinotransferase
ECB94_23020	COG0583	DNA-binding transcription factor activity
ECB94_23035	COG0579	oxidoreductase
ECB94_23050	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECB94_23065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ECB94_23085	COG2264	protein methyltransferase activity
ECB94_23100	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ECB94_23135	COG1067	ATP-dependent peptidase activity
ECB94_23145	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ECB94_23155	COG2140	Oxalate decarboxylase
ECB94_23160	COG2942	2-epimerase
ECB94_23165	COG3716	PTS system mannose fructose sorbose family IID component
ECB94_23170	COG3715	PTS system
ECB94_23175	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_23175	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_23190	COG1609	Transcriptional regulator
ECB94_23210	COG0019	diaminopimelate decarboxylase activity
ECB94_23220	COG0405	Gamma-glutamyltransferase
ECB94_23230	COG3122	Protein conserved in bacteria
ECB94_23240	COG0010	Belongs to the arginase family
ECB94_23245	COG1166	arginine decarboxylase activity
ECB94_23250	COG3284	Transcriptional regulator
ECB94_23255	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_23275	COG1278	Cold shock
ECB94_23280	COG0402	S-adenosylhomocysteine deaminase activity
ECB94_23285	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ECB94_23290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ECB94_23295	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ECB94_23300	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ECB94_23305	COG3397	chitin binding
ECB94_23310	COG0133	tryptophan synthase activity
ECB94_23315	COG2986	histidine ammonia-lyase
ECB94_23320	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ECB94_23325	COG0010	Belongs to the arginase family
ECB94_23330	COG1228	amidohydrolase
ECB94_23345	COG0179	Fumarylacetoacetate (FAA) hydrolase
ECB94_23355	COG0583	DNA-binding transcription factor activity
ECB94_23375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ECB94_23380	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ECB94_23385	COG1845	cytochrome c oxidase, subunit III
ECB94_23405	COG1612	heme a metabolic process
ECB94_23410	COG0109	protoheme IX farnesyltransferase activity
ECB94_23420	COG0765	amino acid transport
ECB94_23425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ECB94_23430	COG0765	amino acid transport
ECB94_23435	COG1126	abc transporter atp-binding protein
ECB94_23445	COG1288	antiporter activity
ECB94_23455	COG2186	Transcriptional regulator
ECB94_23465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECB94_23475	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ECB94_23485	COG0583	DNA-binding transcription factor activity
ECB94_23490	COG2814	Major facilitator Superfamily
ECB94_23495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ECB94_23505	COG0784	Response regulator, receiver
ECB94_23505	COG0835	chemotaxis
ECB94_23510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ECB94_23525	COG0366	Alpha amylase catalytic
ECB94_23530	COG3083	sulfuric ester hydrolase activity
ECB94_23535	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ECB94_23540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_23555	COG3706	GGDEF domain
ECB94_23580	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ECB94_23590	COG4145	pantothenate transmembrane transporter activity
ECB94_23595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECB94_23600	COG0800	Aldolase
ECB94_23615	COG3706	GGDEF domain
ECB94_23620	COG0546	phosphoglycolate phosphatase activity
ECB94_23630	COG0784	Response regulator, receiver
ECB94_23630	COG2205	protein histidine kinase activity
ECB94_23635	COG1858	cytochrome C peroxidase
ECB94_23640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_23645	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ECB94_23655	COG3069	C4-dicarboxylate transmembrane transporter activity
ECB94_23675	COG3706	GGDEF domain
ECB94_23680	COG0583	DNA-binding transcription factor activity
ECB94_23685	COG2197	response regulator
ECB94_23695	COG0697	spore germination
ECB94_23700	COG1288	antiporter activity
ECB94_23705	COG3608	succinylglutamate desuccinylase aspartoacylase
ECB94_23715	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECB94_23725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ECB94_23755	COG0714	Associated with various cellular activities
ECB94_23795	COG1462	curli production assembly transport component CsgG
ECB94_23825	COG3842	ATPase activity
ECB94_23860	COG0366	Alpha amylase catalytic
ECB94_23895	COG1609	Transcriptional regulator
ECB94_23900	COG1447	Phosphotransferase system cellobiose-specific component IIA
ECB94_23905	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECB94_23910	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECB94_23915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ECB94_23950	COG0733	neurotransmitter:sodium symporter activity
ECB94_23960	COG1794	racemase activity, acting on amino acids and derivatives
ECB94_23965	COG3706	GGDEF domain
ECB94_23990	COG2200	EAL domain
ECB94_23990	COG2771	luxR family
ECB94_24005	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ECB94_24020	COG0583	DNA-binding transcription factor activity
ECB94_24030	COG2897	thiosulfate sulfurtransferase activity
ECB94_24040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ECB94_24045	COG0303	'Molybdopterin
ECB94_24050	COG0302	gtp cyclohydrolase
ECB94_24070	COG0038	chloride channel
ECB94_24075	COG0523	cobalamin synthesis protein
ECB94_24090	COG0714	Associated with various cellular activities
ECB94_24110	COG2304	oxidoreductase activity
ECB94_24130	COG3706	GGDEF domain
ECB94_24145	COG0641	radical SAM
ECB94_24155	COG0786	glutamate:sodium symporter activity
ECB94_24170	COG0625	glutathione transferase activity
ECB94_24180	COG0110	maltose O-acetyltransferase activity
ECB94_24185	COG3300	MHYT domain
ECB94_24185	COG5001	Diguanylate cyclase
ECB94_24190	COG1869	D-ribose catabolic process
ECB94_24195	COG1129	ABC transporter
ECB94_24200	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECB94_24205	COG1879	ABC-type sugar transport system periplasmic component
ECB94_24210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECB94_24220	COG1979	alcohol dehydrogenase
ECB94_24235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ECB94_24255	COG1136	(ABC) transporter
ECB94_24265	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ECB94_24275	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECB94_24280	COG1172	Belongs to the binding-protein-dependent transport system permease family
ECB94_24295	COG2390	Transcriptional regulator
ECB94_24300	COG0667	Aldo Keto reductase
ECB94_24305	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ECB94_24315	COG1070	Carbohydrate kinase
ECB94_24320	COG1454	alcohol dehydrogenase
ECB94_24345	COG3153	acetyltransferase
ECB94_24380	COG0642	Histidine kinase
ECB94_24385	COG0745	RESPONSE REGULATOR receiver
ECB94_24390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ECB94_24400	COG0747	negative chemotaxis
ECB94_24410	COG0444	Belongs to the ABC transporter superfamily
ECB94_24415	COG0534	Mate efflux family protein
ECB94_24425	COG1414	Transcriptional regulator
ECB94_24435	COG1136	(ABC) transporter
ECB94_24455	COG1355	regulation of microtubule-based process
ECB94_24470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECB94_24470	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_24470	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ECB94_24475	COG0383	alpha-mannosidase activity
ECB94_24480	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_24480	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ECB94_24480	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_24485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ECB94_24500	COG2814	Major facilitator Superfamily
ECB94_24530	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ECB94_24550	COG3901	Regulator of nitric oxide reductase transcription
ECB94_24550	COG0348	domain, Protein
ECB94_24560	COG3070	regulator of competence-specific genes
ECB94_24575	COG3448	diguanylate cyclase activity
ECB94_24575	COG4175	Glycine betaine
ECB94_24580	COG4176	ABC-type proline glycine betaine transport system permease component
ECB94_24595	COG0583	DNA-binding transcription factor activity
ECB94_24620	COG4989	oxidoreductase activity
ECB94_24625	COG0739	heme binding
ECB94_24650	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECB94_24665	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ECB94_24670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ECB94_24675	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ECB94_24685	COG0549	Belongs to the carbamate kinase family
ECB94_24695	COG0573	inorganic phosphate transmembrane transporter activity
ECB94_24705	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ECB94_24715	COG2205	protein histidine kinase activity
ECB94_24715	COG5002	protein histidine kinase activity
ECB94_24715	COG0784	Response regulator, receiver
ECB94_24720	COG0446	pyridine nucleotide-disulphide oxidoreductase
ECB94_24720	COG1902	pentaerythritol trinitrate reductase activity
ECB94_24730	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ECB94_24800	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_24805	COG0456	acetyltransferase
ECB94_24820	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ECB94_24825	COG2153	protein acetylation
ECB94_24830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECB94_24845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECB94_24870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ECB94_24875	COG3152	Membrane
ECB94_24895	COG0456	acetyltransferase
ECB94_24905	COG1683	Conserved Protein
ECB94_24945	COG3408	Glycogen debranching enzyme
ECB94_24945	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
ECB94_24950	COG3608	succinylglutamate desuccinylase aspartoacylase
ECB94_24950	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ECB94_24955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ECB94_24960	COG2068	MobA-Related Protein
ECB94_24965	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ECB94_24970	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ECB94_24970	COG2080	2 iron, 2 sulfur cluster binding
ECB94_24975	COG0402	S-adenosylhomocysteine deaminase activity
ECB94_24980	COG2252	PERMEase
ECB94_24985	COG1846	Transcriptional regulator
ECB94_24990	COG0493	'glutamate synthase
ECB94_24990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ECB94_24995	COG0402	S-adenosylhomocysteine deaminase activity
ECB94_25000	COG3119	arylsulfatase activity
ECB94_25005	COG3119	arylsulfatase activity
ECB94_25010	COG0210	DNA helicase
ECB94_25020	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ECB94_25025	COG0545	Peptidyl-prolyl cis-trans isomerase
ECB94_25040	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ECB94_25045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECB94_25050	COG3706	GGDEF domain
ECB94_25065	COG0546	phosphoglycolate phosphatase activity
ECB94_25075	COG0840	transmembrane signaling receptor activity
ECB94_25080	COG0814	amino acid
ECB94_25090	COG2824	Alkylphosphonate utilization operon protein PhnA
ECB94_25095	COG3250	beta-galactosidase activity
ECB94_25105	COG1024	Enoyl-CoA hydratase
ECB94_25110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ECB94_25115	COG1960	acyl-CoA dehydrogenase activity
ECB94_25125	COG0183	Belongs to the thiolase family
ECB94_25135	COG1960	acyl-CoA dehydrogenase activity
ECB94_25140	COG1024	Enoyl-CoA hydratase
ECB94_25145	COG1024	Enoyl-CoA hydratase
ECB94_25155	COG1028	Short-chain dehydrogenase reductase Sdr
ECB94_25175	COG2226	methyltransferase
ECB94_25185	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ECB94_25210	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ECB94_25215	COG0346	lactoylglutathione lyase activity
ECB94_25230	COG1063	alcohol dehydrogenase
ECB94_25245	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ECB94_25315	COG3038	cytochrome b561
ECB94_25320	COG2353	YceI-like domain
ECB94_25330	COG2116	formate transmembrane transporter activity
ECB94_25335	COG0583	DNA-binding transcription factor activity
ECB94_25345	COG3593	DNA synthesis involved in DNA repair
ECB94_25350	COG0737	Belongs to the 5'-nucleotidase family
ECB94_25380	COG2827	Endonuclease containing a URI domain
ECB94_25400	COG1289	transmembrane transporter activity
ECB94_25405	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ECB94_25435	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ECB94_25450	COG0640	Transcriptional regulator
ECB94_25470	COG1328	CTP reductase activity
ECB94_25475	COG0602	queuosine metabolic process
ECB94_25485	COG4067	protein conserved in archaea
ECB94_25485	COG0189	ligase activity
ECB94_25500	COG1492	cobalamin metabolic process
ECB94_25505	COG0725	ABC transporter, periplasmic molybdate-binding protein
ECB94_25510	COG4149	molybdate abc transporter
ECB94_25515	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ECB94_25525	COG3706	GGDEF domain
ECB94_25535	COG0745	RESPONSE REGULATOR receiver
ECB94_25535	COG3706	GGDEF domain
ECB94_25545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ECB94_25550	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ECB94_25585	COG0023	Translation Initiation Factor
ECB94_25600	COG1181	Belongs to the D-alanine--D-alanine ligase family
ECB94_25605	COG3266	domain, Protein
ECB94_25610	COG0045	succinate-CoA ligase (ADP-forming) activity
ECB94_25610	COG1042	CoA-binding domain protein
ECB94_25610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ECB94_25615	COG0583	DNA-binding transcription factor activity
ECB94_25655	COG0784	Response regulator, receiver
ECB94_25655	COG2198	Histidine kinase
ECB94_25655	COG5002	protein histidine kinase activity
ECB94_25660	COG1879	ABC-type sugar transport system periplasmic component
ECB94_25665	COG1803	Methylglyoxal synthase
ECB94_25685	COG1765	OsmC-like protein
ECB94_25690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ECB94_25690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ECB94_25695	COG0668	transmembrane transport
ECB94_25705	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ECB94_25745	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ECB94_25755	COG0556	nucleotide-excision repair
ECB94_25775	COG1196	nuclear chromosome segregation
ECB94_25785	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ECB94_25795	COG2204	response regulator
ECB94_25830	COG1061	Type III restriction enzyme res subunit
ECB94_25855	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ECB94_25855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ECB94_25870	COG1858	cytochrome C peroxidase
ECB94_25905	COG0419	ATPase involved in DNA repair
ECB94_25910	COG0420	3'-5' exonuclease activity
ECB94_25920	COG2205	protein histidine kinase activity
ECB94_25925	COG0745	RESPONSE REGULATOR receiver
ECB94_25945	COG2195	Cleaves the N-terminal amino acid of tripeptides
ECB94_25965	COG0366	Alpha amylase catalytic
ECB94_25970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ECB94_25980	COG1538	Outer membrane efflux protein
ECB94_25985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_26005	COG3530	Putative quorum-sensing-regulated virulence factor
ECB94_26015	COG3263	regulation of cellular component size
ECB94_26020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ECB94_26025	COG3118	belongs to the thioredoxin family
ECB94_26030	COG2207	Transcriptional regulator
ECB94_26030	COG1917	Cupin 2, conserved barrel domain protein
ECB94_26050	COG0189	ligase activity
ECB94_26050	COG4067	protein conserved in archaea
ECB94_26060	COG0189	ligase activity
ECB94_26070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ECB94_26080	COG4181	ATPase activity
ECB94_26090	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ECB94_26130	COG4533	DNA binding
ECB94_26140	COG2050	protein possibly involved in aromatic compounds catabolism
ECB94_26145	COG4783	chaperone-mediated protein folding
ECB94_26165	COG2267	carboxylic ester hydrolase activity
ECB94_26180	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ECB94_26185	COG0513	Belongs to the DEAD box helicase family
ECB94_26195	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ECB94_26205	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ECB94_26210	COG0393	Putative heavy-metal-binding
ECB94_26255	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ECB94_26275	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ECB94_26285	COG0583	DNA-binding transcription factor activity
ECB94_26310	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ECB94_26320	COG0513	Belongs to the DEAD box helicase family
ECB94_26325	COG1742	UPF0060 membrane protein
ECB94_26335	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ECB94_26345	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
ECB94_26350	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ECB94_26355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_26380	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ECB94_26385	COG1461	Dihydroxyacetone kinase
ECB94_26390	COG2376	Dihydroxyacetone kinase
ECB94_26400	COG1309	transcriptional regulator
ECB94_26420	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ECB94_26425	COG1263	PTS System
ECB94_26425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ECB94_26430	COG1609	Transcriptional regulator
ECB94_26435	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ECB94_26440	COG1280	lysine exporter protein (LysE YggA)
ECB94_26450	COG3284	Transcriptional regulator
ECB94_26455	COG1501	Belongs to the glycosyl hydrolase 31 family
ECB94_26460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ECB94_26465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ECB94_26490	COG2084	Dehydrogenase
ECB94_26495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ECB94_26500	COG1349	DNA-binding transcription factor activity
ECB94_26570	COG1960	acyl-CoA dehydrogenase activity
ECB94_26580	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_26585	COG3384	dioxygenase
ECB94_26600	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_26610	COG0179	Fumarylacetoacetate (FAA) hydrolase
ECB94_26620	COG3971	2-oxopent-4-enoate hydratase activity
ECB94_26630	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ECB94_26640	COG1846	Transcriptional regulator
ECB94_26655	COG1278	Cold shock
ECB94_26670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ECB94_26670	COG1017	nitric oxide dioxygenase activity
ECB94_26675	COG3604	Transcriptional regulator
ECB94_26685	COG0519	Catalyzes the synthesis of GMP from XMP
ECB94_26705	COG1012	belongs to the aldehyde dehydrogenase family
ECB94_26715	COG1177	transmembrane transport
ECB94_26720	COG1176	ABC-type spermidine putrescine transport system, permease component I
ECB94_26725	COG3842	ATPase activity
ECB94_26730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ECB94_26740	COG0174	glutamine synthetase
ECB94_26745	COG0174	glutamine synthetase
ECB94_26750	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ECB94_26760	COG4191	Histidine kinase
ECB94_26770	COG0573	inorganic phosphate transmembrane transporter activity
ECB94_26780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ECB94_26790	COG2850	peptidyl-arginine hydroxylation
ECB94_26800	COG3366	ferrous iron transmembrane transporter activity
ECB94_26805	COG0700	Nucleoside recognition
ECB94_26810	COG0840	transmembrane signaling receptor activity
ECB94_26815	COG0583	DNA-binding transcription factor activity
ECB94_26825	COG4172	Belongs to the ABC transporter superfamily
ECB94_26830	COG4239	(ABC) transporter, permease
ECB94_26835	COG4174	ABC transporter (Permease)
ECB94_26840	COG4166	transmembrane transport
ECB94_26845	COG3706	GGDEF domain
ECB94_26865	COG3316	Transposase and inactivated derivatives
ECB94_26870	COG2885	chlorophyll binding
ECB94_26875	COG5492	domain, Protein
ECB94_26875	COG4932	domain protein
ECB94_26920	COG3316	Transposase and inactivated derivatives
ECB94_26930	COG3316	Transposase and inactivated derivatives
ECB94_27020	COG2003	Belongs to the UPF0758 family
ECB94_27060	COG0741	lytic transglycosylase activity
ECB94_27265	COG4932	domain protein
ECB94_27265	COG5492	domain, Protein
ECB94_27295	COG4932	domain protein
ECB94_27295	COG5492	domain, Protein
ECB94_27530	COG4790	Type iii secretion
ECB94_27540	COG3316	Transposase and inactivated derivatives
ECB94_27625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ECB94_27655	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ECB94_27675	COG3710	Transcriptional regulator
ECB94_27700	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ECB94_27730	COG2801	Transposase and inactivated derivatives