locus-tag	class	description
AL543_00005	ENOG4105C4X	radical SAM domain protein
AL543_00010	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AL543_00015	ENOG4105G2Y	Transcriptional regulator
AL543_00020	ENOG4105CNH	Multidrug resistance protein MdtL
AL543_00025	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AL543_00045	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_00075	ENOG4105GMB	type VI secretion system effector, hcp1 family
AL543_00085	ENOG4105MVE	transcriptional regulator
AL543_00090	ENOG4105ZXK	Dehydrogenase
AL543_00095	ENOG4105G63	Type III effector Hrp-dependent
AL543_00100	ENOG4105FB2	class II Aldolase
AL543_00105	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
AL543_00110	ENOG4105EXW	epimerase dehydratase
AL543_00115	ENOG4105C6Z	Gluconate
AL543_00220	ENOG4105DVF	Cytosine-specific methyltransferase
AL543_00265	ENOG4105CAR	Terminase, large subunit
AL543_00280	ENOG4108XTP	Transcriptional regulator
AL543_00310	ENOG4105CPQ	Dehydrogenase
AL543_00315	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AL543_00320	ENOG4108IQK	o-acetylhomoserine
AL543_00325	ENOG4105EXG	Transcriptional regulator
AL543_00330	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AL543_00350	ENOG4105BZU	Histidine kinase
AL543_00360	ENOG4107SSZ	Phosphatase
AL543_00365	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AL543_00370	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AL543_00375	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
AL543_00395	ENOG4105BZW	Glycerate kinase
AL543_00400	ENOG4105C6Z	Gluconate
AL543_00405	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
AL543_00410	ENOG4105CA0	peroxidase
AL543_00415	ENOG4108NVR	Methyl-accepting chemotaxis
AL543_00420	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
AL543_00425	ENOG41090JE	Utilization Protein
AL543_00430	ENOG4105D4P	Coproporphyrinogen iii oxidase
AL543_00435	ENOG4105WQ5	TonB family
AL543_00440	ENOG41090AP	transport protein
AL543_00445	ENOG4106GFD	transport protein
AL543_00450	ENOG4107R4I	Periplasmic binding protein
AL543_00455	ENOG4105EHG	Permease protein
AL543_00460	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AL543_00500	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_00505	ENOG4105QVC	MOSC domain-containing protein
AL543_00505	ENOG4105QVC	MOSC domain-containing protein
AL543_00510	ENOG4105EKE	dihydroorotase
AL543_00530	ENOG4105KAF	membrAne
AL543_00540	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
AL543_00545	ENOG4105CKW	Inner membrane protein yedI
AL543_00550	ENOG4105C5H	ABC transporter
AL543_00560	ENOG4108ESY	Metal dependent phosphohydrolase
AL543_00565	ENOG4105VEQ	Cold shock protein
AL543_00595	ENOG4105E98	transcriptional regulator DeoR family
AL543_00605	ENOG4105CGH	5'-nucleotidase
AL543_00620	ENOG4105EG2	ABC transporter, permease
AL543_00625	ENOG4105D56	permease protein
AL543_00630	ENOG4107FKK	extracellular solute-binding protein family 1
AL543_00635	ENOG4108IJ9	(ABC) transporter
AL543_00640	ENOG4108HK0	-acetyltransferase
AL543_00655	ENOG4105K8R	UPF0145 protein
AL543_00660	ENOG41086KC	Transcriptional regulator
AL543_00680	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
AL543_00685	ENOG4107R88	Chemotaxis protein (CheV)
AL543_00690	ENOG4105K56	Transcriptional regulator
AL543_00695	ENOG4106TD9	Diguanylate cyclase
AL543_00710	ENOG4105BZU	Histidine kinase
AL543_00730	ENOG4105ETT	transcriptional Regulator, LysR family
AL543_00735	ENOG4108K0B	C-di-gmp phosphodiesterase
AL543_00745	ENOG4105EUB	pirin domain protein
AL543_00750	ENOG4105NBK	UPF0345 protein
AL543_00760	ENOG4105E5W	Transporter
AL543_00775	ENOG4105DAN	ATP-dependent protease
AL543_00785	ENOG4108JQ5	ABC transporter
AL543_00790	ENOG4105CC0	LysR family Transcriptional regulator
AL543_00795	ENOG4105DAA	L-lactate
AL543_00800	ENOG4105DMF	Dehydrogenase
AL543_00810	ENOG4105VNT	transposase (IS4 family) protein
AL543_00815	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AL543_00830	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
AL543_00845	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
AL543_00850	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AL543_00860	ENOG4108RS6	transposase
AL543_00865	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AL543_00870	ENOG4105CDA	abc transporter atp-binding protein
AL543_00880	ENOG4106TNF	Periplasmic binding protein
AL543_00885	ENOG4105GBT	ABC transporter
AL543_00890	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
AL543_00900	ENOG4105DR5	peptidase
AL543_00905	ENOG4105CTS	PTS system mannitol-specific
AL543_00910	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
AL543_00915	ENOG4105E61	Mannitol repressor protein
AL543_00920	ENOG4105EP9	oxidoreductase
AL543_00950	ENOG4108KTG	Membrane protein, drug metabolite transporter
AL543_00965	ENOG4105DUM	transcriptional regulator, lysR family
AL543_00970	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AL543_00985	ENOG4108IPJ	Membrane
AL543_00990	ENOG4108RYK	Nad-dependent epimerase dehydratase
AL543_00995	ENOG4105JQN	Transcriptional regulator
AL543_01010	ENOG4105EMU	Dehydrogenase
AL543_01015	ENOG4105JQN	Transcriptional regulator
AL543_01035	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AL543_01040	ENOG4105D5Q	Arginine ornithine antiporter
AL543_01045	ENOG4105CXN	decarboxylase
AL543_01055	ENOG4105VJY	transcriptional regulator
AL543_01075	ENOG4107RGH	Aldehyde dehydrogenase
AL543_01080	ENOG4105EW9	transcriptional regulator AsnC family
AL543_01085	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_01095	ENOG4105CK7	Sodium proline symporter
AL543_01105	ENOG4105C26	Dehydrogenase
AL543_01120	ENOG4105E6M	Sulphatase-modifying factor protein
AL543_01130	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AL543_01135	ENOG4107QZV	Type I secretion membrane fusion protein
AL543_01160	ENOG4105CWX	Alpha-1,2-mannosidase
AL543_01170	ENOG4105BZU	Histidine kinase
AL543_01180	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_01185	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AL543_01190	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AL543_01195	ENOG4105BZU	Histidine kinase
AL543_01200	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_01205	ENOG4108V3W	Chemotaxis protein, CheW
AL543_01210	ENOG4108V3W	Chemotaxis protein, CheW
AL543_01215	ENOG4105CBS	Chea signal transduction histidine kinase
AL543_01220	ENOG4108VYJ	response regulator receiver protein
AL543_01230	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
AL543_01235	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AL543_01240	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AL543_01245	ENOG4108JQ6	ABC transporter
AL543_01250	ENOG4105DIJ	Phosphoethanolamine transferase
AL543_01255	ENOG4108RS6	transposase
AL543_01260	ENOG4105DHQ	Histidine kinase
AL543_01265	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AL543_01275	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
AL543_01295	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AL543_01300	ENOG4107RUE	extracellular solute-binding protein family 1
AL543_01305	ENOG4106RMF	ParB family
AL543_01340	ENOG4105CDY	transcriptional regulatory protein
AL543_01345	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AL543_01355	ENOG4108YYI	Protein of unknown function (DUF2810)
AL543_01360	ENOG41061ZR	Transcriptional regulator
AL543_01365	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
AL543_01370	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
AL543_01375	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AL543_01380	ENOG4108WC9	type VI secretion system effector, hcp1 family
AL543_01385	ENOG4105CS6	Rhs element vgr protein
AL543_01410	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AL543_01420	ENOG4105C8P	)-transporter
AL543_01425	ENOG4108Q67	UPF0319 protein
AL543_01455	ENOG4105EYK	Phosphatidylglycerophosphatase B
AL543_01465	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
AL543_01470	ENOG41080T7	secreted protein
AL543_01490	ENOG4105D6U	Sodium Glutamate Symporter
AL543_01495	ENOG4105YE1	PilZ domain
AL543_01505	ENOG4105VMP	Transcriptional regulator
AL543_01520	ENOG4105EFX	secretion protein, HlyD family
AL543_01525	ENOG4105KK7	inner membrane protein YiaW
AL543_01530	ENOG4106TD9	Diguanylate cyclase
AL543_01545	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AL543_01555	ENOG4107SEY	Conserved Protein
AL543_01560	ENOG4108XDN	Transcriptional regulator
AL543_01565	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AL543_01570	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
AL543_01580	ENOG4105C1J	atp-dependent rna helicase
AL543_01590	ENOG4105CVA	phosphate
AL543_01595	ENOG4105C8U	phosphate abc transporter
AL543_01600	ENOG4105E2Z	phosphate ABC transporter (Permease
AL543_01605	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AL543_01610	ENOG4105BZU	Histidine kinase
AL543_01620	ENOG4105DWD	nucleoside recognition domain protein
AL543_01625	ENOG4105CHH	sulfate transporter
AL543_01635	ENOG4105DR5	peptidase
AL543_01640	ENOG4105BZU	Histidine kinase
AL543_01645	ENOG4105EQ2	LysR family Transcriptional regulator
AL543_01650	ENOG4105E5M	Multidrug resistance protein D
AL543_01655	ENOG4108Z4X	TRANSCRIPTIONal
AL543_01690	ENOG4105EHV	domain protein
AL543_01695	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AL543_01705	ENOG4108ZHJ	Organic hydroperoxide resistance protein
AL543_01710	ENOG4105K56	Transcriptional regulator
AL543_01745	ENOG4105BZ1	(ABC) transporter
AL543_01755	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AL543_01765	ENOG4105CR8	Transcriptional regulator
AL543_01770	ENOG4105P66	Membrane
AL543_01775	ENOG4108UHU	Aldolase
AL543_01780	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
AL543_01790	ENOG4105DEI	Mannitol dehydrogenase
AL543_01795	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AL543_01800	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
AL543_01805	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AL543_01810	ENOG4105C6F	GntR Family Transcriptional Regulator
AL543_01815	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
AL543_01820	ENOG4105C1J	atp-dependent rna helicase
AL543_01840	ENOG4105VW4	glutaredoxin 3
AL543_01855	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_01865	ENOG4108RS6	transposase
AL543_01870	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_01880	ENOG4105C5A	transporter
AL543_01890	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
AL543_01895	ENOG4107W52	maltose operon periplasmic protein
AL543_01905	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
AL543_01930	ENOG4108VGI	doxx family
AL543_01935	ENOG4105D03	DNA-3-methyladenine glycosylase II
AL543_01940	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AL543_01950	ENOG4107QPK	)-transporter
AL543_01955	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AL543_01960	ENOG4106YYS	transcriptional regulatory protein
AL543_01965	ENOG4105DN9	Na H antiporter
AL543_01970	ENOG41074DU	domain protein
AL543_01975	ENOG4108P2H	Inner membrane protein YjiG
AL543_01980	ENOG4105CK2	sodium dicarboxylate symporter
AL543_02025	ENOG4107RH7	Nicotinate phosphoribosyltransferase
AL543_02030	ENOG4105D9R	oxidoreductase
AL543_02040	ENOG4108M8H	domain protein
AL543_02045	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
AL543_02055	ENOG4108RS6	transposase
AL543_02060	ENOG4105D3G	Pseudouridine synthase
AL543_02120	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AL543_02125	ENOG4108JUB	Transcriptional regulator
AL543_02150	ENOG4105CS6	Rhs element vgr protein
AL543_02180	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
AL543_02185	ENOG4105C2J	ABC transporter
AL543_02190	ENOG4105CNN	ABC, transporter
AL543_02195	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
AL543_02200	ENOG4108RVA	ribokinase
AL543_02205	ENOG4105ETE	Transcriptional regulator (LacI family
AL543_02210	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
AL543_02215	ENOG4108I5U	Uridine phosphorylase
AL543_02225	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AL543_02230	ENOG4105CXY	transporter
AL543_02245	ENOG4105CQZ	Histidine kinase
AL543_02250	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AL543_02270	ENOG4105D5U	fad dependent oxidoreductase
AL543_02280	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AL543_02295	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
AL543_02300	ENOG4105ETE	Transcriptional regulator (LacI family
AL543_02305	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AL543_02315	ENOG4105CIC	tryptophan-specific transport protein
AL543_02320	ENOG4105C0F	tryptophanase EC 4.1.99.1
AL543_02330	ENOG4105VRT	cytoplasmic protein
AL543_02340	ENOG4105BZU	Histidine kinase
AL543_02345	ENOG4105VEQ	Cold shock protein
AL543_02380	ENOG4107QVM	von Willebrand factor, type A
AL543_02400	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AL543_02420	ENOG4105D9N	nucleoside
AL543_02425	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AL543_02435	ENOG4108JUA	Transcriptional regulator
AL543_02440	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AL543_02445	ENOG4105VEQ	Cold shock protein
AL543_02465	ENOG4108UNF	response regulator
AL543_02475	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AL543_02480	ENOG4105C5I	Dehydrogenase
AL543_02505	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AL543_02510	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AL543_02580	ENOG4105VZ1	Replication Protein
AL543_02605	ENOG4105ED4	portal protein
AL543_02740	ENOG4105C1J	atp-dependent rna helicase
AL543_02745	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AL543_02750	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
AL543_02755	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AL543_02760	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_02765	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AL543_02770	ENOG4105BZU	Histidine kinase
AL543_02780	ENOG4107S6Z	Na H antiporter
AL543_02785	ENOG4105E5M	Multidrug resistance protein D
AL543_02795	ENOG4105BZU	Histidine kinase
AL543_02800	ENOG4105KUU	lipolytic protein G-D-S-L family
AL543_02805	ENOG4106M3D	hemolysin
AL543_02810	ENOG4108N3W	hemolysin secretion protein
AL543_02815	ENOG4107G87	m6 family metalloprotease domain protein
AL543_02835	ENOG4105DHS	permease protein
AL543_02840	ENOG4105CM4	permease protein
AL543_02845	ENOG4108IPW	abc transporter atp-binding protein
AL543_02855	ENOG4107ENK	receptor
AL543_02865	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AL543_02875	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL543_02885	ENOG4105HX0	Transcriptional regulator
AL543_02890	ENOG4105VG5	Membrane
AL543_02905	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
AL543_02915	ENOG410667J	hydrolase
AL543_02960	ENOG4105NWF	RbsD or FucU transport
AL543_02965	ENOG4107W7X	Aldolase
AL543_02980	ENOG4105CNN	ABC, transporter
AL543_02995	ENOG4108IJF	Heavy metal efflux pump, CzcA
AL543_03025	ENOG4108M1A	Chitin-binding protein
AL543_03030	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
AL543_03040	ENOG4105CVA	phosphate
AL543_03050	ENOG4108IEC	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
AL543_03055	ENOG4105C1J	atp-dependent rna helicase
AL543_03065	ENOG4105E0M	Sulfatase
AL543_03070	ENOG4107RE1	Inosine-guanosine kinase
AL543_03085	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AL543_03105	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AL543_03120	ENOG4105RKW	reductase (By
AL543_03130	ENOG4108I0Y	(ABC) transporter
AL543_03135	ENOG4105CV6	ABC transporter, permease
AL543_03140	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AL543_03155	ENOG4105P4J	Allophanate hydrolase, subunit 1
AL543_03160	ENOG4105E7W	lamb ycsf family protein
AL543_03165	ENOG4105CMR	udp-glucose 4-epimerase
AL543_03175	ENOG4105E0U	tyrosine-specific transport protein
AL543_03185	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
AL543_03190	ENOG4105C1J	atp-dependent rna helicase
AL543_03200	ENOG4106RE7	Cytochrome
AL543_03205	ENOG4105C5W	Aldolase
AL543_03210	ENOG4108YZ4	nudix hydrolase
AL543_03220	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
AL543_03230	ENOG4105E5Z	arginine transporter ATP-binding subunit
AL543_03235	ENOG4106PMH	Extracellular solute-binding protein family 3
AL543_03240	ENOG4105GBT	ABC transporter
AL543_03245	ENOG4105DMR	ABC, transporter
AL543_03250	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AL543_03255	ENOG4107RSM	transcriptional regulator
AL543_03275	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
AL543_03295	ENOG4105VXR	cytoplasmic protein
AL543_03300	ENOG4108ISG	Major Facilitator
AL543_03305	ENOG4105K63	Thioredoxin
AL543_03310	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AL543_03320	ENOG4105CND	Glycosyl transferase, family 2
AL543_03330	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AL543_03335	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
AL543_03340	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
AL543_03350	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AL543_03355	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AL543_03385	ENOG41082IR	Excinuclease ABC C subunit domain protein
AL543_03395	ENOG4108QGH	periplasmic
AL543_03400	ENOG4105BZU	Histidine kinase
AL543_03420	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AL543_03425	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AL543_03430	ENOG4105E0C	molybdate abc transporter
AL543_03435	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AL543_03455	ENOG4105EM2	membrane
AL543_03460	ENOG41088T4	Helicase IV
AL543_03485	ENOG41080IJ	Diacylglycerol kinase
AL543_03500	ENOG4108RWI	nicotinamidase
AL543_03505	ENOG4108Z5K	methylglyoxal synthase
AL543_03510	ENOG4108SV3	Tmao reductase system periplasmic protein tort
AL543_03515	ENOG4105BZU	Histidine kinase
AL543_03520	ENOG4105CA9	Pyruvate kinase
AL543_03525	ENOG4105CXY	transporter
AL543_03535	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
AL543_03545	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
AL543_03565	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AL543_03570	ENOG4105BZU	Histidine kinase
AL543_03585	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AL543_03590	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AL543_03600	ENOG4105CK1	PTS System
AL543_03605	ENOG4105VCP	PTS System
AL543_03615	ENOG4105E2D	ec 3.2.1.52
AL543_03625	ENOG4105CHU	acetyl-coa acetyltransferase
AL543_03635	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
AL543_03720	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AL543_03725	ENOG4107RCV	ABC transporter, permease
AL543_03730	ENOG4105C4Y	ABC transporter
AL543_03735	ENOG4105CXY	transporter
AL543_03740	ENOG4105BZU	Histidine kinase
AL543_03745	ENOG4108KX4	response regulator
AL543_03750	ENOG4105DHT	Metal Dependent Phosphohydrolase
AL543_03770	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AL543_03780	ENOG4108ZNS	ferredoxin-type protein NapF
AL543_03785	ENOG4105BZU	Histidine kinase
AL543_03790	ENOG4105WH1	Two component transcriptional regulator luxr family
AL543_03795	ENOG4105EJQ	L-serine dehydratase
AL543_03800	ENOG4105CEE	C4-dicarboxylate transporter
AL543_03805	ENOG4108N3W	hemolysin secretion protein
AL543_03810	ENOG4107VXZ	Hydrolase
AL543_03815	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AL543_03820	ENOG4105UYK	outer membrane protein a
AL543_03825	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_03830	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AL543_03885	ENOG4105J12	Multidrug resistance protein mdtN
AL543_03890	ENOG4105JQN	Transcriptional regulator
AL543_03905	ENOG41080HT	Transcriptional regulator, arsr family
AL543_03930	ENOG4108RS6	transposase
AL543_03935	ENOG4108RCM	Nitroreductase
AL543_03945	ENOG4105ETT	transcriptional Regulator, LysR family
AL543_03955	ENOG4105RA2	Membrane
AL543_03980	ENOG4108M3J	Dehydrogenase
AL543_04010	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AL543_04015	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AL543_04025	ENOG4107RHR	regulatoR
AL543_04035	ENOG4105KHC	sulfurtransferase
AL543_04045	ENOG4105D06	uba thif-type nad fad binding protein
AL543_04050	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AL543_04055	ENOG4105EUJ	GTP cyclohydrolase i
AL543_04060	ENOG4105E0X	reductase
AL543_04065	ENOG4105CKU	formyltetrahydrofolate synthetase
AL543_04070	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AL543_04075	ENOG4105C0A	alcohol dehydrogenase
AL543_04080	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
AL543_04095	ENOG4105PAD	Hydrolase
AL543_04100	ENOG4105NXH	GreA GreB family elongation factor
AL543_04105	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
AL543_04110	ENOG4108JPW	Aminotransferase
AL543_04115	ENOG4107STF	Involved in phosphonate degradation (By similarity)
AL543_04130	ENOG4107RCV	ABC transporter, permease
AL543_04145	ENOG4105DUX	Transporter
AL543_04170	ENOG4105E43	Extracellular solute-binding protein, family 5
AL543_04175	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AL543_04180	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AL543_04185	ENOG4108JQ5	ABC transporter
AL543_04195	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AL543_04210	ENOG4105CYM	Glutathione S-transferase
AL543_04230	ENOG4105KA0	thioesterase Superfamily protein
AL543_04250	ENOG4105CWB	LysR family transcriptional Regulator
AL543_04255	ENOG4105CD5	CoA-binding domain protein
AL543_04265	ENOG4105CPF	Cell wall formation (By similarity)
AL543_04275	ENOG4108ZJT	translation initiation factor, Sui1
AL543_04285	ENOG4105BZ1	(ABC) transporter
AL543_04290	ENOG4105BZ1	(ABC) transporter
AL543_04295	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
AL543_04320	ENOG4105C0W	non-ribosomal peptide synthetase
AL543_04325	ENOG4105EYM	Major Facilitator superfamily
AL543_04420	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AL543_04425	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AL543_04440	ENOG4105BZU	Histidine kinase
AL543_04450	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AL543_04460	ENOG4105BZU	Histidine kinase
AL543_04495	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AL543_04505	ENOG4105DU1	integral membrane protein, terc
AL543_04510	ENOG4105CGH	5'-nucleotidase
AL543_04515	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
AL543_04520	ENOG4108UQ5	membrane protein YcdZ
AL543_04525	ENOG4105DUM	transcriptional regulator, lysR family
AL543_04530	ENOG4105TMB	Formate nitrite transporter
AL543_04540	ENOG4105DS1	cytochrome b561
AL543_04550	ENOG4105BZU	Histidine kinase
AL543_04555	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_04560	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_04575	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
AL543_04580	ENOG4108MX5	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses (By similarity)
AL543_04585	ENOG4105QEK	Transcriptional regulator
AL543_04595	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AL543_04600	ENOG41069H7	transport system small permease component
AL543_04605	ENOG4108ERU	trap dicarboxylate transporter subunit DctP
AL543_04615	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
AL543_04620	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
AL543_04625	ENOG4105CE4	GlcNAc 6-P deacetylase
AL543_04650	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AL543_04655	ENOG4105CKI	cobalamin synthesis protein
AL543_04660	ENOG4105CMQ	Chloride channel
AL543_04675	ENOG4107KBT	8-Amino-7-oxononanoate synthase
AL543_04680	ENOG4108MGY	Histidine kinase
AL543_04685	ENOG4105EYH	Exonuclease
AL543_04690	ENOG4107RFY	SbcCD D subunit
AL543_04695	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
AL543_04700	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
AL543_04705	ENOG4105DE4	1-phosphofructokinase
AL543_04710	ENOG4105DM4	PTS System
AL543_04715	ENOG4108M8H	domain protein
AL543_04720	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AL543_04725	ENOG4105CGF	Aromatic amino acid aminotransferase
AL543_04730	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
AL543_04735	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
AL543_04745	ENOG4105E7U	AraC family transcriptional regulator
AL543_04815	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AL543_04825	ENOG4105YGK	Pfam:UPF0157
AL543_04845	ENOG4105D9U	N-acetyltransferase
AL543_04925	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AL543_05120	ENOG4105K8R	UPF0145 protein
AL543_05140	ENOG4105K8R	UPF0145 protein
AL543_05200	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AL543_05205	ENOG4105K8R	UPF0145 protein
AL543_05220	ENOG4105YGK	Pfam:UPF0157
AL543_05255	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
AL543_05270	ENOG4108UW5	maltose o-acetyltransferase
AL543_05280	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
AL543_05285	ENOG41080ET	plasmid maintenance system killer protein
AL543_05290	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
AL543_05360	ENOG4108MK9	spermidine N(1)-acetyltransferase
AL543_05380	ENOG4105D9U	N-acetyltransferase
AL543_05490	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
AL543_05545	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AL543_05550	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AL543_05565	ENOG4105YGK	Pfam:UPF0157
AL543_05575	ENOG4105D9U	N-acetyltransferase
AL543_05620	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AL543_05630	ENOG4108RS6	transposase
AL543_05635	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AL543_05640	ENOG41082NX	50s ribosomal protein l35
AL543_05645	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AL543_05650	ENOG4105C22	threonyL-tRNA synthetase
AL543_05655	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AL543_05665	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AL543_05670	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AL543_05675	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL543_05680	ENOG4108PC0	lipolytic protein G-D-S-L family
AL543_05685	ENOG4108UHE	carbonic anhydrase
AL543_05700	ENOG4105DZ1	carboxypeptidase
AL543_05705	ENOG4105J4Q	Transcriptional regulator
AL543_05715	ENOG4108JQ6	ABC transporter
AL543_05720	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AL543_05740	ENOG4105C4X	radical SAM domain protein
AL543_05745	ENOG4105CBG	Sulfatase
AL543_05750	ENOG41061MV	Arylsulfatase
AL543_05755	ENOG4105BZU	Histidine kinase
AL543_05775	ENOG4105CHR	reductase
AL543_05780	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
AL543_05785	ENOG4108UHU	Aldolase
AL543_05790	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
AL543_05810	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
AL543_05835	ENOG4105CJW	magnesium transporter
AL543_05840	ENOG4105CZK	Aspartate kinase
AL543_05845	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
AL543_05850	ENOG4108JPW	Aminotransferase
AL543_05855	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
AL543_05870	ENOG4105UQX	Mate efflux family protein
AL543_05880	ENOG41090A4	Pterin carbinolamine dehydratase
AL543_05885	ENOG4105MIR	Phenylalanine 4-monooxygenase
AL543_05890	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AL543_05905	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AL543_05915	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AL543_05920	ENOG4105C37	(CBS) domain
AL543_05925	ENOG4108UKZ	OsmC family
AL543_05930	ENOG4107YWA	deoxycytidylate deaminase
AL543_05955	ENOG4105DVH	amino acid
AL543_05960	ENOG4106TD9	Diguanylate cyclase
AL543_05970	ENOG4108VAC	response regulator
AL543_05975	ENOG4108HRK	Histidine kinase
AL543_05990	ENOG4105D60	lipoprotein releasing system transmembrane protein
AL543_05995	ENOG4105C19	ABC transporter
AL543_06005	ENOG4107RGM	aldo keto reductase
AL543_06010	ENOG4107T9C	Alpha amylase catalytic region
AL543_06040	ENOG4105D4Y	metalloprotease
AL543_06050	ENOG4105EIF	outer membrane protein W
AL543_06060	ENOG41061WM	D-Alanyl-D-Alanine
AL543_06065	ENOG4105C0B	DNA polymerase III (alpha subunit)
AL543_06070	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AL543_06075	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AL543_06080	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AL543_06085	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AL543_06090	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AL543_06095	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
AL543_06100	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL543_06105	ENOG4105DZP	Membrane-associated zinc metalloprotease
AL543_06110	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AL543_06115	ENOG4105KNE	Phosphatidate cytidylyltransferase
AL543_06120	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AL543_06125	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AL543_06130	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AL543_06135	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AL543_06140	ENOG4105CE9	30S ribosomal protein S2
AL543_06145	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AL543_06150	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AL543_06155	ENOG4108T8E	UPF0325 protein
AL543_06160	ENOG4108ZAI	phosphatidylglycerophosphatase a
AL543_06165	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AL543_06170	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AL543_06175	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AL543_06190	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AL543_06195	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AL543_06200	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AL543_06205	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AL543_06210	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
AL543_06220	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AL543_06225	ENOG4105C7N	Xanthine uracil vitamin C permease
AL543_06230	ENOG4105CIN	aminoacyl-histidine dipeptidase
AL543_06235	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AL543_06240	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AL543_06250	ENOG4105C8J	)-transporter
AL543_06265	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AL543_06275	ENOG4105CJ2	(LipO)protein
AL543_06285	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AL543_06290	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AL543_06295	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AL543_06300	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AL543_06305	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AL543_06310	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AL543_06315	ENOG4105M85	Bola protein
AL543_06320	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AL543_06330	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AL543_06335	ENOG4105EYM	Major Facilitator superfamily
AL543_06345	ENOG4105K6V	RNA polymerase
AL543_06360	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AL543_06365	ENOG4107S0N	DJ-1 family
AL543_06370	ENOG4105C9B	Cysteine desulfurase
AL543_06375	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AL543_06380	ENOG4105CUZ	uba thif-type nad fad binding protein
AL543_06385	ENOG4105CA3	membrane-bound lytic murein transglycosylase
AL543_06395	ENOG4107QZM	n-acetylglutamate synthase
AL543_06410	ENOG4107QYX	exodeoxyribonuclease v alpha
AL543_06415	ENOG4107QKA	exodeoxyribonuclease V beta
AL543_06420	ENOG4105DSY	exodeoxyribonuclease V, gamma
AL543_06435	ENOG4105X2V	dna damage-inducible protein
AL543_06440	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
AL543_06445	ENOG4108RS6	transposase
AL543_06460	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AL543_06475	ENOG4108Y51	tRNA-binding protein
AL543_06480	ENOG41060NJ	transcriptional regulator
AL543_06485	ENOG4105VNT	transposase (IS4 family) protein
AL543_06490	ENOG4105CNT	hydrolase family 2
AL543_06500	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AL543_06505	ENOG4108IQE	Amp-dependent synthetase and ligase
AL543_06515	ENOG4105ETT	transcriptional Regulator, LysR family
AL543_06520	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AL543_06525	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AL543_06545	ENOG4105EAC	phosphoserine phosphatase
AL543_06555	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
AL543_06560	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
AL543_06565	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
AL543_06570	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AL543_06580	ENOG4105D9N	nucleoside
AL543_06585	ENOG4105EYA	deoxyribonuclease
AL543_06595	ENOG4105BZG	amino acid carrier protein
AL543_06610	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AL543_06615	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AL543_06620	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
AL543_06625	ENOG4105D98	threonine synthase
AL543_06630	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AL543_06645	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AL543_06655	ENOG41065U4	response regulator
AL543_06660	ENOG4105BZU	Histidine kinase
AL543_06670	ENOG4105N5T	Radical SAM Protein
AL543_06685	ENOG4105CBC	glutamate synthase
AL543_06690	ENOG4105BZ8	glutamate synthase
AL543_06700	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AL543_06710	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AL543_06715	ENOG4105EN6	Membrane
AL543_06720	ENOG4105VP0	transcriptional regulator, lysR family
AL543_06725	ENOG4105EJ9	Membrane
AL543_06730	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AL543_06735	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AL543_06740	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AL543_06750	ENOG4105M6F	mutator MutT protein
AL543_06755	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AL543_06775	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AL543_06780	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AL543_06785	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AL543_06790	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AL543_06795	ENOG4105DFU	Cell wall formation (By similarity)
AL543_06800	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AL543_06810	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AL543_06815	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AL543_06820	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AL543_06825	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AL543_06830	ENOG4105CJN	penicillin-binding protein
AL543_06835	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AL543_06840	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AL543_06850	ENOG4107QN2	dihydrolipoyl dehydrogenase
AL543_06855	ENOG4107QSN	dihydrolipoamide acetyltransferase
AL543_06860	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AL543_06865	ENOG41073TP	transcriptional regulator
AL543_06870	ENOG4105CGH	5'-nucleotidase
AL543_06875	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AL543_06880	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AL543_06885	ENOG4105T95	Thiol disulfide interChange protein
AL543_06890	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AL543_06895	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
AL543_06905	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AL543_06915	ENOG4107QHF	type ii secretion system protein e
AL543_06920	ENOG4105D7Q	type ii secretion system
AL543_06925	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AL543_06930	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AL543_06935	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
AL543_06940	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
AL543_06945	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AL543_06950	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AL543_06955	ENOG4105IPS	esterase
AL543_06960	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AL543_06965	ENOG4108SX3	cytoplasmic protein
AL543_06970	ENOG41087AY	ADP-Ribose pyrophosphatase
AL543_06975	ENOG4105DFG	type I secretion outer membrane protein
AL543_06985	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AL543_06990	ENOG4108NVR	Methyl-accepting chemotaxis
AL543_07000	ENOG4105I7R	Adenylate cyclase
AL543_07005	ENOG4107IX6	phosphate transport regulator
AL543_07010	ENOG4105CJ3	phosphate transporter
AL543_07015	ENOG4106MWK	domain protein
AL543_07030	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AL543_07040	ENOG4105E0U	tyrosine-specific transport protein
AL543_07045	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
AL543_07050	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AL543_07055	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AL543_07065	ENOG4105DXN	mazG family
AL543_07070	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AL543_07075	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AL543_07080	ENOG4105BZU	Histidine kinase
AL543_07085	ENOG4108K0B	C-di-gmp phosphodiesterase
AL543_07100	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AL543_07105	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AL543_07110	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AL543_07115	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AL543_07120	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AL543_07125	ENOG4105C3F	Signal peptidase i
AL543_07130	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AL543_07135	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
AL543_07150	ENOG4105EMN	RNA polymerase sigma factor
AL543_07160	ENOG4108IYU	L-aspartate oxidase
AL543_07170	ENOG4105Y75	tpr repeat protein
AL543_07175	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AL543_07185	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AL543_07190	ENOG4105D0A	hydroxylase
AL543_07200	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AL543_07210	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AL543_07215	ENOG4105E66	phosphoriboisomerase A
AL543_07220	ENOG4108JQ1	Dehydrogenase
AL543_07225	ENOG4108ZP8	Acetolactate synthase small subunit
AL543_07230	ENOG4105C7K	acetolactate synthase
AL543_07235	ENOG4108IQE	Amp-dependent synthetase and ligase
AL543_07240	ENOG41064T2	transcriptional regulator, lysR family
AL543_07250	ENOG410841Q	phosphoesterase PA-phosphatase related protein
AL543_07260	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AL543_07265	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AL543_07270	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AL543_07275	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AL543_07335	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AL543_07350	ENOG4108K5H	permease YjgP YjgQ family protein
AL543_07355	ENOG4108M8S	permease YjgP YjgQ family protein
AL543_07360	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AL543_07365	ENOG4105MYG	DNA polymerase iii, chi subunit
AL543_07370	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AL543_07390	ENOG4108M3P	Membrane
AL543_07395	ENOG4105C5I	Dehydrogenase
AL543_07400	ENOG4105D3G	Pseudouridine synthase
AL543_07405	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AL543_07415	ENOG4108IAB	Phoh family
AL543_07420	ENOG4105DBV	ornithine carbamoyltransferase
AL543_07425	ENOG4105CXT	aspartate transcarbamylase
AL543_07430	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
AL543_07435	ENOG4105KME	endoribonuclease L-psp
AL543_07440	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
AL543_07445	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AL543_07450	ENOG4105VFK	BolA family
AL543_07460	ENOG4105E3I	toluene tolerance
AL543_07465	ENOG4107PE3	Mammalian cell entry related domain protein
AL543_07470	ENOG4105CY3	ABC transporter, permease
AL543_07475	ENOG4105DHJ	ABC, transporter
AL543_07490	ENOG4105C2X	Arabinose 5-phosphate isomerase
AL543_07495	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AL543_07505	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AL543_07510	ENOG4108IUZ	ABC transporter
AL543_07515	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AL543_07520	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AL543_07525	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AL543_07535	ENOG41080Z8	PHOSPHOCARRIER protein
AL543_07540	ENOG4105CJW	magnesium transporter
AL543_07545	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
AL543_07550	ENOG4105N42	UPF0307 protein
AL543_07555	ENOG4107T0D	ABC, transporter
AL543_07560	ENOG4106SMU	thiamine transporter membrane protein
AL543_07565	ENOG4105DP9	ABC transporter
AL543_07570	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AL543_07575	ENOG4105DFU	Cell wall formation (By similarity)
AL543_07585	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL543_07590	ENOG4105F0N	pyrophosphate phospho-hydrolase
AL543_07600	ENOG41066HZ	AIG2-like family
AL543_07605	ENOG4105MA0	exported protein
AL543_07610	ENOG4105CFU	surface antigen
AL543_07615	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AL543_07620	ENOG4108UUE	Transcriptional regulator
AL543_07635	ENOG4105C19	ABC transporter
AL543_07655	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
AL543_07660	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AL543_07665	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AL543_07670	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AL543_07675	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
AL543_07685	ENOG4105C1J	atp-dependent rna helicase
AL543_07690	ENOG4107YB6	acetyltransferase, (GNAT) family
AL543_07695	ENOG4108SXK	Transporter Drug Metabolite Exporter family
AL543_07700	ENOG4105FHY	Opacity-associated protein A
AL543_07705	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AL543_07715	ENOG4108ZT0	50S ribosomal protein l17
AL543_07720	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AL543_07725	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AL543_07730	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AL543_07735	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL543_07745	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AL543_07750	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AL543_07755	ENOG4105VPB	50S ribosomal protein L30
AL543_07760	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AL543_07765	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AL543_07770	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AL543_07775	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AL543_07780	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AL543_07785	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL543_07790	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AL543_07795	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AL543_07800	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AL543_07805	ENOG41083MP	50s ribosomal protein l29
AL543_07810	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AL543_07815	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AL543_07820	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AL543_07825	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AL543_07830	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL543_07835	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AL543_07840	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AL543_07845	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AL543_07850	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AL543_07855	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AL543_07860	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AL543_07865	ENOG4105E68	Sulfatase
AL543_07870	ENOG4108UV7	flagellar protein motX
AL543_07875	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AL543_07880	ENOG4105D44	asparaginase
AL543_07885	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AL543_07900	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
AL543_07905	ENOG4105C5H	ABC transporter
AL543_07915	ENOG4105DNZ	Alpha Beta Hydrolase
AL543_07925	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
AL543_07930	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AL543_07940	ENOG4105C26	Dehydrogenase
AL543_07950	ENOG4105C8Y	Acetylornithine aminotransferase
AL543_07955	ENOG4105DDQ	anthranilate synthase
AL543_07960	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AL543_07975	ENOG4105C31	Tryptophanyl-tRNA synthetase
AL543_07980	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AL543_07985	ENOG4105DJV	ribulose-phosphate 3-epimerase
AL543_07990	ENOG4105DFE	Dna adenine methylase
AL543_08000	ENOG4105D49	3-dehydroquinate synthase
AL543_08005	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AL543_08010	ENOG4105E4G	Type IV pilus
AL543_08035	ENOG4108JQC	penicillin-binding protein 1A
AL543_08045	ENOG4105EHV	domain protein
AL543_08050	ENOG4107QN2	dihydrolipoyl dehydrogenase
AL543_08060	ENOG4105CH7	arginosuccinase
AL543_08065	ENOG4105CDH	Citrulline--aspartate ligase
AL543_08070	ENOG4105CAS	nag kinase
AL543_08075	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AL543_08080	ENOG4105CWC	Acetylornithine deacetylase
AL543_08085	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AL543_08095	ENOG4105D7W	serine acetyltransferase
AL543_08100	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AL543_08105	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AL543_08110	ENOG4107YZP	Rhodanese domain protein
AL543_08115	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AL543_08125	ENOG4105E33	succinate dehydrogenase
AL543_08130	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
AL543_08135	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
AL543_08140	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AL543_08145	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AL543_08165	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AL543_08170	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AL543_08195	ENOG4105CP7	Triose-phosphate isomerase
AL543_08205	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AL543_08210	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
AL543_08215	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AL543_08220	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AL543_08230	ENOG4105ETE	Transcriptional regulator (LacI family
AL543_08235	ENOG4105C25	Primosomal protein n'
AL543_08240	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AL543_08245	ENOG4105C6K	Malic enzyme
AL543_08250	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
AL543_08255	ENOG4105C28	cystathionine
AL543_08260	ENOG4105CFH	Aspartokinase
AL543_08265	ENOG4105SYT	Methylenetetrahydrofolate reductase
AL543_08270	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
AL543_08275	ENOG4105CBT	Fructose-1,6-bisphosphatase
AL543_08280	ENOG4105CTQ	phosphohexokinase
AL543_08285	ENOG41076HS	cation diffusion facilitator family transporter
AL543_08295	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AL543_08300	ENOG4105E0F	Histidine kinase
AL543_08310	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AL543_08320	ENOG4108IJ0	Aspartate ammonia-lyase
AL543_08325	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
AL543_08330	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AL543_08340	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AL543_08350	ENOG4107QN1	sodium solute
AL543_08355	ENOG4105EX9	Membrane
AL543_08360	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AL543_08365	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AL543_08370	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AL543_08375	ENOG4105CB5	ATP-dependent DNA helicase recG
AL543_08380	ENOG4105C2W	permease
AL543_08385	ENOG4105E0F	Histidine kinase
AL543_08390	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AL543_08395	ENOG4105D17	glycoside hydrolase, family 3 domain protein
AL543_08400	ENOG4105CNN	ABC, transporter
AL543_08405	ENOG4105C2J	ABC transporter
AL543_08420	ENOG4108RRZ	Transcription elongation factor GreB
AL543_08425	ENOG4105BZM	domain protein
AL543_08435	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AL543_08440	ENOG4105MJ2	Competence protein
AL543_08445	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AL543_08450	ENOG4107RK2	ADP-ribose diphosphatase NudE
AL543_08455	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
AL543_08460	ENOG4105PIC	general secretion pathway protein N
AL543_08465	ENOG4105U1E	general secretion pathway protein M
AL543_08470	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
AL543_08475	ENOG4108RTD	type II secretion system protein K
AL543_08480	ENOG4108WWZ	General secretion pathway protein J
AL543_08485	ENOG4105X5Z	General secretion pathway protein I
AL543_08490	ENOG4105VWV	general secretion pathway protein h
AL543_08495	ENOG4108VAU	general secretion pathway protein G
AL543_08500	ENOG4105D7Q	type ii secretion system
AL543_08505	ENOG4107QHF	type ii secretion system protein e
AL543_08515	ENOG4108XKW	General secretion pathway protein C
AL543_08520	ENOG4105VEJ	Heat shock protein
AL543_08525	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AL543_08530	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AL543_08540	ENOG4105SUU	thioesterase domain
AL543_08545	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AL543_08570	ENOG4105C5F	glutamine synthetase
AL543_08580	ENOG4105CUX	Signal transduction histidine kinase
AL543_08585	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AL543_08590	ENOG4105BZU	Histidine kinase
AL543_08595	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
AL543_08680	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AL543_08685	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AL543_08695	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
AL543_08730	ENOG4108YGG	dna repair protein
AL543_08775	ENOG4108Y73	Membrane
AL543_08785	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
AL543_08790	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AL543_08795	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AL543_08800	ENOG4105CAK	Cell division ATP-binding protein ftsE
AL543_08805	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AL543_08810	ENOG4106H78	methyltransferase
AL543_08845	ENOG4108RMU	ferritin dps family protein
AL543_08850	ENOG4105D58	Diguanylate phosphodiesterase
AL543_08855	ENOG410829K	Lysine exporter protein (Lyse ygga)
AL543_08860	ENOG4108EUD	Lysophospholipase
AL543_08865	ENOG4105DQF	Hydrolase
AL543_08880	ENOG4105BZU	Histidine kinase
AL543_08885	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
AL543_08890	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AL543_08895	ENOG4105CT0	Protein of unknown function, DUF484
AL543_08900	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AL543_08905	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AL543_08915	ENOG4105XQ6	frataxin-like protein
AL543_08920	ENOG4107T0K	Adenylate cyclase
AL543_08930	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AL543_08935	ENOG41076E6	Uroporphyrinogen-III Synthase
AL543_08940	ENOG4105ECF	c-methyltransferase
AL543_08945	ENOG410601J	HemY protein
AL543_08950	ENOG4105D4P	Coproporphyrinogen iii oxidase
AL543_08955	ENOG4105XCT	Protein of unknown function (DUF2489)
AL543_08960	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
AL543_08970	ENOG4106RE7	Cytochrome
AL543_08975	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AL543_08985	ENOG4105C2M	dna polymerase I
AL543_08990	ENOG4105KD7	acetyltransferase
AL543_08995	ENOG4105D52	delta-aminolevulinic acid dehydratase
AL543_09000	ENOG4105F8V	Hydrolase, tatD family
AL543_09010	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AL543_09020	ENOG4105X6C	Flagellar basal body-associated protein FliL
AL543_09030	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
AL543_09035	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AL543_09040	ENOG4105E55	glycerol-3-phosphate acyltransferase
AL543_09045	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AL543_09055	ENOG4107R73	Mate efflux family protein
AL543_09060	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AL543_09065	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AL543_09070	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AL543_09075	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AL543_09080	ENOG4105JC1	sterol-binding domain protein
AL543_09085	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AL543_09090	ENOG4105CGY	Dna recombination protein
AL543_09100	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AL543_09175	ENOG4105CBX	hi0933 family
AL543_09180	ENOG4108V6B	universal stress protein B
AL543_09185	ENOG41090A1	ferritin
AL543_09195	ENOG4108M6U	Universal stress protein A
AL543_09200	ENOG4105EMK	carboxylate amino acid amine transporter
AL543_09210	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
AL543_09215	ENOG4105BZU	Histidine kinase
AL543_09220	ENOG4108VVK	transcriptional Regulator, AsnC
AL543_09230	ENOG4105CNH	Multidrug resistance protein MdtL
AL543_09240	ENOG4105DC7	peptidase M24
AL543_09240	ENOG4105DC7	peptidase M24
AL543_09245	ENOG4105D41	biosynthesis protein thiH
AL543_09250	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AL543_09255	ENOG4105WHD	thiamine biosynthesis protein ThiS
AL543_09260	ENOG4105D06	uba thif-type nad fad binding protein
AL543_09270	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AL543_09275	ENOG4105WMR	Protein CrcB homolog
AL543_09290	ENOG4105DFP	Integrase
AL543_09300	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
AL543_09305	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL543_09415	ENOG4108RR8	protoporphyrinogen oxidase
AL543_09420	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AL543_09425	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AL543_09430	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AL543_09435	ENOG4105CHU	acetyl-coa acetyltransferase
AL543_09440	ENOG4105F52	Transcriptional regulator
AL543_09445	ENOG4105CZQ	inner membrane transport protein YdhC
AL543_09455	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AL543_09460	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AL543_09465	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AL543_09470	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AL543_09475	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AL543_09480	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AL543_09485	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AL543_09490	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AL543_09495	ENOG410684E	atp synthase
AL543_09500	ENOG4105FA0	parb-like partition protein
AL543_09505	ENOG4107QJE	Chromosome Partitioning Protein
AL543_09510	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AL543_09515	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AL543_09520	ENOG4105QTB	Flavodoxin
AL543_09535	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AL543_09540	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AL543_09545	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AL543_09550	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AL543_09565	ENOG4105E5Q	amino acid AbC transporter
AL543_09570	ENOG4105EAB	amino acid AbC transporter
AL543_09575	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AL543_09580	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AL543_09585	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AL543_09590	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AL543_09605	ENOG4108ZNX	Heat shock protein
AL543_09610	ENOG4105JKW	Valine--pyruvate aminotransferase
AL543_09615	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AL543_09620	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
AL543_09635	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AL543_09650	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AL543_09655	ENOG4105C7B	Threonine dehydratase
AL543_09660	ENOG4105C01	Dihydroxy-acid dehydratase
AL543_09665	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AL543_09680	ENOG4105C0P	Mg chelatase subunit ChlI
AL543_09685	ENOG4106HNH	Acyl-transferase
AL543_09690	ENOG4108Z33	Thiol disulfide Interchange Protein
AL543_09695	ENOG4105E27	serine threonine protein kinase
AL543_09705	ENOG4105PC1	Conserved Protein
AL543_09715	ENOG4108N23	SpoOM-related protein
AL543_09720	ENOG4108UT2	hemolysin iii
AL543_09730	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AL543_09735	ENOG4105C1A	potassium transporter peripheral membrane
AL543_09740	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AL543_09750	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AL543_09755	ENOG4108WZM	domain protein
AL543_09760	ENOG4105C79	DNA protecting protein DprA
AL543_09765	ENOG4108RPN	Protein smg homolog
AL543_09770	ENOG4108WI1	Dna topoisomerase
AL543_09775	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AL543_09780	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AL543_09785	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AL543_09795	ENOG4105E2X	shikimate dehydrogenase
AL543_09805	ENOG4108Z0R	Transferase
AL543_09850	ENOG4105EMY	transcriptional regulator
AL543_09855	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AL543_09860	ENOG4105W0Z	cytoplasmic protein
AL543_09865	ENOG4105BZS	acriflavin resistance protein
AL543_09870	ENOG410624X	efflux transporter, rnd family, mfp subunit
AL543_09875	ENOG4105Y7M	Transcriptional regulator, TetR family
AL543_09880	ENOG4105C4R	Atp-dependent dna helicase
AL543_09885	ENOG4105MPD	Cytochrome
AL543_09925	ENOG4105DEF	Extracellular solute-binding protein, family 5
AL543_09930	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AL543_09935	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AL543_09990	ENOG4108ZXE	
AL543_10035	ENOG4105DC8	reductase
AL543_10040	ENOG4105D6S	protein involved in catabolism of external DNA
AL543_10045	ENOG4105DGW	oligopeptidase A
AL543_10050	ENOG4105C4R	Atp-dependent dna helicase
AL543_10075	ENOG4105FR1	rard protein
AL543_10080	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AL543_10095	ENOG4105E0K	tonB-dependent siderophore receptor
AL543_10100	ENOG4105E0A	ABC, transporter
AL543_10105	ENOG4105J76	Periplasmic binding protein
AL543_10110	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
AL543_10115	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
AL543_10125	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL543_10130	ENOG4105C5Y	PTS System
AL543_10140	ENOG4105DSJ	YicC domain protein
AL543_10145	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AL543_10150	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AL543_10155	ENOG4105VNT	transposase (IS4 family) protein
AL543_10160	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
AL543_10165	ENOG4105D1S	lipid A biosynthesis
AL543_10170	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AL543_10175	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AL543_10190	ENOG4105KDC	50s ribosomal protein l28
AL543_10195	ENOG4105W0E	50S ribosomal protein L33
AL543_10205	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AL543_10210	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AL543_10215	ENOG4105M5K	heptosyltransferase
AL543_10225	ENOG4106WTF	Glycosyl transferase, family 2
AL543_10230	ENOG4105DKP	glycosyl transferase, family 9
AL543_10235	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
AL543_10260	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AL543_10265	ENOG4108ST3	glycosyltransferase
AL543_10275	ENOG4105XA0	heptosyltransferase ii
AL543_10295	ENOG4107T94	Endo-14-beta-xylanase
AL543_10300	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AL543_10305	ENOG4108QY5	Ferric enterobactin transport protein
AL543_10310	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AL543_10320	ENOG4105CMR	udp-glucose 4-epimerase
AL543_10325	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AL543_10335	ENOG4107QRS	glycosyltransferase group 2 family protein
AL543_10355	ENOG4105ESV	Glycosyl transferase, family 4
AL543_10365	ENOG4105CUY	Mechanosensitive ion channel
AL543_10370	ENOG4108RG0	uracil-dna glycosylase
AL543_10375	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
AL543_10380	ENOG4105R2J	Conserved Protein
AL543_10390	ENOG4105K70	DNA-binding protein
AL543_10400	ENOG4105C12	Phosphoribosylglycinamide synthetase
AL543_10405	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AL543_10410	ENOG4105W1Y	Transcriptional regulator
AL543_10415	ENOG4108M3R	transcriptional activator CadC
AL543_10420	ENOG4105D5Q	Arginine ornithine antiporter
AL543_10425	ENOG4105CXN	decarboxylase
AL543_10430	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_10440	ENOG4105E0K	tonB-dependent siderophore receptor
AL543_10445	ENOG4108UHU	Aldolase
AL543_10450	ENOG4105C6Z	Gluconate
AL543_10455	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
AL543_10460	ENOG4105C01	Dihydroxy-acid dehydratase
AL543_10465	ENOG4105DIQ	Transcriptional regulator
AL543_10470	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AL543_10475	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AL543_10480	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AL543_10485	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AL543_10490	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AL543_10495	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AL543_10500	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AL543_10520	ENOG4105D8G	Major Facilitator superfamily
AL543_10525	ENOG4105BZU	Histidine kinase
AL543_10540	ENOG4105C9X	ppx gppa phosphatase
AL543_10545	ENOG4105C1J	atp-dependent rna helicase
AL543_10550	ENOG4105K63	Thioredoxin
AL543_10555	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AL543_10565	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AL543_10575	ENOG4107QK7	reductase
AL543_10620	ENOG4105JIM	Phosphatidylserine synthase
AL543_10635	ENOG4105D4A	Cell wall formation (By similarity)
AL543_10640	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AL543_10645	ENOG4105CS9	pantothenic acid kinase
AL543_10670	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AL543_10675	ENOG4105PM1	preprotein translocase subunit SecE
AL543_10680	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AL543_10685	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AL543_10690	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AL543_10695	ENOG4108VZM	50s ribosomal protein L10
AL543_10700	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AL543_10705	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AL543_10710	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AL543_10715	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
AL543_10720	ENOG4105E09	nadh pyrophosphatase
AL543_10725	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AL543_10730	ENOG41062JF	Transcriptional regulator
AL543_10740	ENOG41063SB	peptidase
AL543_10745	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AL543_10755	ENOG4105C8P	)-transporter
AL543_10760	ENOG4105DJ4	phosphatidylserine decarboxylase
AL543_10765	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AL543_10770	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AL543_10815	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AL543_10820	ENOG4105K8N	protein family UPF0079, ATPase
AL543_10825	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AL543_10830	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AL543_10835	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AL543_10840	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AL543_10845	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AL543_10850	ENOG4107QJR	hflk protein
AL543_10855	ENOG4105EPW	hflc protein
AL543_10865	ENOG41069P5	Protein slyX homolog
AL543_10875	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AL543_10880	ENOG4105WWK	YheO domain protein
AL543_10885	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
AL543_10890	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
AL543_10900	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AL543_10905	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AL543_10910	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AL543_10915	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AL543_10920	ENOG4105W53	bacterioferritin-associated ferredoxin
AL543_10925	ENOG4108UQY	Iron-storage protein
AL543_10930	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AL543_10935	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
AL543_10940	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AL543_10945	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AL543_10955	ENOG4105CDU	Replicative dna helicase
AL543_10960	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AL543_10965	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AL543_10970	ENOG4107QP8	phosphohexose isomerase
AL543_10980	ENOG4105MYN	Zinc uptake regulation protein
AL543_10985	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AL543_10990	ENOG4105P4Z	Phage shock protein G
AL543_11010	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AL543_11015	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AL543_11020	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AL543_11090	ENOG4105EEQ	Na H antiporter
AL543_11095	ENOG4105C3R	Methionine synthase
AL543_11100	ENOG4105CFH	Aspartokinase
AL543_11105	ENOG4105C5R	Aminotransferase
AL543_11115	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AL543_11120	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AL543_11125	ENOG41086KC	Transcriptional regulator
AL543_11130	ENOG4108UUM	single-stranded DNA-binding protein
AL543_11135	ENOG41062P1	Diguanylate cyclase phosphodiesterase
AL543_11155	ENOG4105E4G	Type IV pilus
AL543_11170	ENOG4107QHF	type ii secretion system protein e
AL543_11175	ENOG4105D7Q	type ii secretion system
AL543_11185	ENOG4105X0D	Fimbrial protein
AL543_11220	ENOG4105DFF	Rod shape-determining protein mreb
AL543_11225	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AL543_11230	ENOG4105VQ7	Rod shape-determining protein MreD
AL543_11235	ENOG4108Z03	MAF-like protein
AL543_11240	ENOG4105C03	ribonuclease
AL543_11245	ENOG4105QD6	exported protein
AL543_11255	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
AL543_11260	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
AL543_11265	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AL543_11270	ENOG4105CEU	Arginine dihydrolase
AL543_11280	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AL543_11310	ENOG4108IA2	Sodium pantothenate symporter
AL543_11315	ENOG4105E2D	ec 3.2.1.52
AL543_11320	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
AL543_11335	ENOG41081QV	Universal stress protein
AL543_11350	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
AL543_11355	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AL543_11360	ENOG4105D5Q	Arginine ornithine antiporter
AL543_11365	ENOG4105EAH	synthase
AL543_11370	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AL543_11375	ENOG4105K46	50S ribosomal protein l27
AL543_11380	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AL543_11385	ENOG4105DWK	Membrane
AL543_11390	ENOG4107XM3	UPF0442 protein
AL543_11400	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AL543_11405	ENOG4105NWN	ApaG protein
AL543_11410	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AL543_11415	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AL543_11420	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AL543_11425	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AL543_11430	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AL543_11460	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_11485	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
AL543_11490	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AL543_11495	ENOG4105CEN	a g-specific adenine glycosylase
AL543_11500	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AL543_11505	ENOG4105CSV	Glutaminase
AL543_11515	ENOG4105CSA	Coproporphyrinogen iii oxidase
AL543_11520	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AL543_11535	ENOG4108VIA	integral membrane protein
AL543_11540	ENOG4105II7	pyrroline-5-carboxylate reductase
AL543_11545	ENOG4105DFA	alanine racemase domain protein
AL543_11550	ENOG4105CZX	twitching motility protein
AL543_11555	ENOG4105CZX	twitching motility protein
AL543_11565	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AL543_11570	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AL543_11575	ENOG4108UJU	UPF0301 protein
AL543_11580	ENOG4105D7Z	glutathione synthase
AL543_11585	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AL543_11590	ENOG4105RWS	endonuclease I
AL543_11595	ENOG4105GPY	SprT protein
AL543_11600	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AL543_11610	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AL543_11615	ENOG4108R4R	Iron-regulated virulence regulatory protein
AL543_11620	ENOG4105D05	Receptor
AL543_11625	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AL543_11630	ENOG4105BZA	Phosphoglycerate kinase
AL543_11635	ENOG4105D2N	Aldolase
AL543_11640	ENOG4105D64	Mechanosensitive ion channel
AL543_11645	ENOG4108RS6	transposase
AL543_11650	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
AL543_11655	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
AL543_11660	ENOG4105MPN	Membrane
AL543_11665	ENOG4105CA9	Pyruvate kinase
AL543_11670	ENOG410804X	Transcriptional regulator
AL543_11675	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AL543_11680	ENOG4105CH5	extracellular solute-binding protein, family 7
AL543_11695	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AL543_11700	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AL543_11705	ENOG4105KTH	gatB Yqey
AL543_11710	ENOG4105VCC	30S ribosomal protein S21
AL543_11715	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AL543_11720	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
AL543_11725	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AL543_11735	ENOG4107ZVW	dihydroneopterin aldolase
AL543_11740	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL543_11745	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AL543_11755	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AL543_11760	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AL543_11765	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AL543_11770	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AL543_11775	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AL543_11780	ENOG4108K5P	(LipO)protein
AL543_11785	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AL543_11790	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AL543_11795	ENOG4105C6T	cysteine synthase
AL543_11800	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
AL543_11805	ENOG4108I5D	sulfate abc transporter
AL543_11810	ENOG4105ECW	sulfate abc transporter
AL543_11815	ENOG4108IJ6	ABC transporter
AL543_11820	ENOG4107TH8	cina domain protein
AL543_11825	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AL543_11830	ENOG4105Y3E	Modulates RecA activity (By similarity)
AL543_11835	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AL543_11840	ENOG4105CFH	Aspartokinase
AL543_11845	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AL543_11895	ENOG4107QSA	Oxaloacetate decarboxylase
AL543_11900	ENOG4105D9Q	decarboxylase (Beta subunit)
AL543_11910	ENOG4105W39	Membrane
AL543_11920	ENOG4105D9M	gamma-glutamylcysteine synthetase
AL543_11925	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AL543_11930	ENOG4108JU6	CBS domain protein
AL543_11935	ENOG4106KVJ	cytochrome C assembly protein
AL543_11940	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL543_11945	ENOG4105K5M	30s ribosomal protein S16
AL543_11950	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AL543_11955	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AL543_11960	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AL543_11965	ENOG4105C0H	protease
AL543_11970	ENOG4105C0H	protease
AL543_11980	ENOG4105D6Z	AFG1 family ATPase
AL543_11990	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AL543_11995	ENOG4108UJD	30S ribosomal protein S9
AL543_12000	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AL543_12005	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AL543_12010	ENOG4105EIX	cytochrome c1
AL543_12015	ENOG4107MKT	Stringent starvation protein a
AL543_12020	ENOG4105KB2	stringent starvation protein b
AL543_12025	ENOG4105W4M	Transport-associated protein
AL543_12030	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AL543_12035	ENOG41082RQ	UPF0102 protein
AL543_12040	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
AL543_12045	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AL543_12050	ENOG410630P	Transcriptional regulator
AL543_12055	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
AL543_12060	ENOG41077A9	carbonic anhydrase
AL543_12065	ENOG4105CHH	sulfate transporter
AL543_12070	ENOG4105DA5	(ABC) transporter
AL543_12075	ENOG4105E3A	(ABC) transporter
AL543_12080	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AL543_12085	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AL543_12090	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL543_12095	ENOG4105DJ0	Poly(A) Polymerase
AL543_12100	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AL543_12105	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AL543_12110	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AL543_12115	ENOG4105CQ7	ATP-dependent helicase
AL543_12120	ENOG4105BZ4	penicillin-binding protein
AL543_12125	ENOG4105D78	K07001 NTE family protein
AL543_12130	ENOG4107QIJ	Aconitate hydratase 2
AL543_12135	ENOG4105XTV	UPF0231 protein
AL543_12140	ENOG4108YZA	Nitrogen regulatory protein pii
AL543_12155	ENOG4105E0C	molybdate abc transporter
AL543_12160	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AL543_12170	ENOG4105E2V	Glycosyltransferase 36
AL543_12175	ENOG4105E2D	ec 3.2.1.52
AL543_12180	ENOG4105RD7	BadF BadG BcrA BcrD
AL543_12190	ENOG4108JQ7	(ABC) transporter
AL543_12195	ENOG4105C3U	ABC transporter
AL543_12200	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AL543_12210	ENOG4107QRA	Extracellular solute-binding protein, family 5
AL543_12215	ENOG4105BZU	Histidine kinase
AL543_12220	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AL543_12225	ENOG4105IPI	Membrane
AL543_12235	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AL543_12245	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AL543_12260	ENOG4105DR5	peptidase
AL543_12265	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AL543_12270	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
AL543_12275	ENOG4105FCK	Membrane
AL543_12280	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AL543_12285	ENOG4105HBR	Rna-binding protein
AL543_12290	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AL543_12295	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AL543_12300	ENOG4105EEI	dihydropteroate synthase
AL543_12305	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AL543_12330	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AL543_12335	ENOG4105CHV	Transcription elongation factor NusA
AL543_12340	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AL543_12345	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AL543_12350	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AL543_12355	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AL543_12360	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AL543_12365	ENOG4105RT1	May be involved in cell division (By similarity)
AL543_12370	ENOG410834F	Transcriptional regulator
AL543_12380	ENOG4106RZ4	Peptidase U32
AL543_12385	ENOG4105CFP	Peptidase U32
AL543_12390	ENOG4105BZU	Histidine kinase
AL543_12395	ENOG4105XPQ	lipid carrier protein
AL543_12400	ENOG4108YYD	acetyltransferase
AL543_12415	ENOG4105BZU	Histidine kinase
AL543_12420	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AL543_12425	ENOG4105C1J	atp-dependent rna helicase
AL543_12430	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
AL543_12435	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
AL543_12445	ENOG4105CRK	lysyL-tRNA synthetase
AL543_12450	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AL543_12465	ENOG4105CPC	Aldo Keto reductase
AL543_12475	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
AL543_12480	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AL543_12485	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
AL543_12490	ENOG4105HF0	Membrane
AL543_12495	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AL543_12500	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AL543_12515	ENOG41063Z6	transcriptional regulator, lysR family
AL543_12520	ENOG41080HT	Transcriptional regulator, arsr family
AL543_12525	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AL543_12530	ENOG4105CJR	Integral membrane protein (MviN
AL543_12535	ENOG4105DTN	riboflavin biosynthesis protein ribF
AL543_12540	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AL543_12545	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AL543_12550	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AL543_12555	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AL543_12575	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AL543_12580	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AL543_12585	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AL543_12590	ENOG4108NEV	two component transcriptional regulator, LytTR family
AL543_12595	ENOG4108HRK	Histidine kinase
AL543_12600	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AL543_12615	ENOG4105C5H	ABC transporter
AL543_12620	ENOG4107SC1	transglycosylase
AL543_12625	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
AL543_12630	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AL543_12635	ENOG4108K0B	C-di-gmp phosphodiesterase
AL543_12640	ENOG4107XW0	Spermidine putrescine ABC transporter periplasmic spermidine putrescine-binding protein
AL543_12650	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
AL543_12655	ENOG4108RS6	transposase
AL543_12660	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL543_12665	ENOG4105C34	Pseudouridine synthase
AL543_12670	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AL543_12675	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AL543_12765	ENOG4105D05	Receptor
AL543_12770	ENOG4108SU4	UPF0309 protein
AL543_12785	ENOG4105ETX	regulatoR
AL543_12815	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AL543_12820	ENOG4105CFP	Peptidase U32
AL543_12825	ENOG4105DH7	May be involved in recombination (By similarity)
AL543_12830	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AL543_12835	ENOG4105BZU	Histidine kinase
AL543_12845	ENOG4105C9X	ppx gppa phosphatase
AL543_12850	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
AL543_12855	ENOG4105C8U	phosphate abc transporter
AL543_12860	ENOG4105E2Z	phosphate ABC transporter (Permease
AL543_12865	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AL543_12875	ENOG4105CSR	polyphosphate kinase 2
AL543_12880	ENOG4106N3A	copper homeostasis protein cutc
AL543_12885	ENOG4105D3R	alkyl hydroperoxide reductase
AL543_12890	ENOG4105C5Q	Transcriptional regulator
AL543_12895	ENOG4107QP3	malate synthase g
AL543_12900	ENOG4108I9X	Isocitrate lyase
AL543_12905	ENOG4105W87	Cbs domain
AL543_12910	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AL543_12920	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AL543_12925	ENOG4105VIE	preprotein translocase, subunit YajC
AL543_12930	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AL543_12935	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AL543_12940	ENOG4105ECY	inositol monophosphatase
AL543_12950	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AL543_12960	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AL543_12965	ENOG4108Z4V	iron-sulfur cluster assembly
AL543_12970	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
AL543_12980	ENOG4108ZIT	Ferredoxin, 2FE-2S
AL543_12985	ENOG4105WVQ	Fe-S assembly protein IscX
AL543_12990	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AL543_12995	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AL543_13000	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AL543_13005	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AL543_13010	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AL543_13015	ENOG4105CUT	histidyl-tRNA synthetase
AL543_13020	ENOG4105N21	Membrane
AL543_13025	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AL543_13030	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AL543_13045	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AL543_13050	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AL543_13055	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AL543_13060	ENOG4105DFP	Integrase
AL543_13070	ENOG4105ENA	helicase
AL543_13175	ENOG4106HK8	GPR1 FUN34 yaaH family protein
AL543_13180	ENOG4108RS6	transposase
AL543_13185	ENOG41064T2	transcriptional regulator, lysR family
AL543_13195	ENOG4105BZG	amino acid carrier protein
AL543_13200	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AL543_13205	ENOG4107RSM	transcriptional regulator
AL543_13220	ENOG4105CXC	rtn protein
AL543_13230	ENOG4106YYS	transcriptional regulatory protein
AL543_13235	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AL543_13240	ENOG4105D9Q	decarboxylase (Beta subunit)
AL543_13245	ENOG4107QSA	Oxaloacetate decarboxylase
AL543_13260	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
AL543_13265	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
AL543_13270	ENOG4105CI0	Citrate lyase
AL543_13275	ENOG4105CHY	citrate lyase, alpha
AL543_13280	ENOG4105YGP	holo-ACP synthase CitX
AL543_13285	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
AL543_13300	ENOG4108Z4U	Ferredoxin
AL543_13305	ENOG4105DZ0	fad dependent oxidoreductase
AL543_13345	ENOG4105C0D	helicase
AL543_13375	ENOG4105DFP	Integrase
AL543_13385	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AL543_13390	ENOG4108Z1B	Cyclase dehydrase
AL543_13395	ENOG4105VDB	UPF0125 protein
AL543_13400	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AL543_13405	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AL543_13410	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AL543_13415	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL543_13420	ENOG4105CFG	Acts as a chaperone (By similarity)
AL543_13425	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AL543_13430	ENOG4105X0D	Fimbrial protein
AL543_13460	ENOG4105CFC	Transporter
AL543_13465	ENOG4108Z6B	deaminase
AL543_13475	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AL543_13485	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AL543_13505	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AL543_13510	ENOG4108R96	Methyltransferase, YaeB family
AL543_13515	ENOG4105NRA	50s ribosomal protein l31 type b
AL543_13525	ENOG4105CFC	Transporter
AL543_13530	ENOG4108UPT	UPF0178 protein
AL543_13560	ENOG4105DR9	pseudouridine synthase
AL543_13565	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AL543_13570	ENOG4105CTB	Polyprenyl synthetase
AL543_13580	ENOG4105E14	MotA TolQ exbB proton channel
AL543_13585	ENOG4106VK6	Flagellar motor protein
AL543_13590	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AL543_13600	ENOG4105ETT	transcriptional Regulator, LysR family
AL543_13610	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
AL543_13615	ENOG4105EWT	decarboxylase family
AL543_13620	ENOG4105BZU	Histidine kinase
AL543_13630	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AL543_13635	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
AL543_13640	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
AL543_13645	ENOG4105D01	(LipO)protein
AL543_13650	ENOG4108UMI	ABC transporter, permease
AL543_13655	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AL543_13660	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AL543_13665	ENOG4105D4X	repressor
AL543_13670	ENOG4105C5Y	PTS System
AL543_13675	ENOG4105CG3	alpha amylase, catalytic region
AL543_13680	ENOG4107EXC	regulatoR
AL543_13685	ENOG4105JJR	Histidine kinase
AL543_13720	ENOG4105BZS	acriflavin resistance protein
AL543_13730	ENOG4105KJF	protein tyrosine phosphatase
AL543_13735	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
AL543_13765	ENOG4105D7W	serine acetyltransferase
AL543_13785	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
AL543_13800	ENOG4108MA4	Peptidase M66
AL543_13815	ENOG4105D3Q	Sugar transferase
AL543_13825	ENOG4105DAY	polysaccharide export protein
AL543_13830	ENOG4105D75	Capsular exopolysaccharide family
AL543_13850	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AL543_13860	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AL543_13865	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AL543_13870	ENOG4108Z43	UPF0250 protein
AL543_13875	ENOG4105DZ1	carboxypeptidase
AL543_13880	ENOG4105K6T	rare lipoprotein A
AL543_13885	ENOG4105CNI	cell division protein FtsW
AL543_13890	ENOG4105CJN	penicillin-binding protein
AL543_13895	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AL543_13900	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AL543_13905	ENOG4105DJF	DNA polymerase III, delta' subunit
AL543_13910	ENOG4108U2H	Rare lipoprotein B
AL543_13915	ENOG4105C8T	Leucyl-tRNA synthetase
AL543_13920	ENOG4107PAI	alpha helical protein
AL543_13925	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AL543_13930	ENOG4108JU5	Magnesium and cobalt efflux protein
AL543_13935	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AL543_13940	ENOG4105C9A	Phoh family
AL543_13945	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AL543_13950	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AL543_13955	ENOG4105C5Y	PTS System
AL543_13965	ENOG4105KZ7	phosphocarrier protein hpr
AL543_13975	ENOG4105C6T	cysteine synthase
AL543_13980	ENOG4105EXN	Sulfate transport protein CysZ
AL543_13985	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AL543_13990	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AL543_13995	ENOG41081QG	Porin Gram-negative type
AL543_14005	ENOG4108Z6Z	Transcriptional regulator
AL543_14010	ENOG4105VNT	transposase (IS4 family) protein
AL543_14015	ENOG4105G5H	Membrane
AL543_14020	ENOG4107QX8	SPFH domain, Band 7 family protein
AL543_14025	ENOG4107QR8	Thioredoxin
AL543_14030	ENOG4105E1F	short-chain dehydrogenase reductase
AL543_14035	ENOG4105ECP	epimerase
AL543_14040	ENOG4108RE9	Phosphodiesterase
AL543_14055	ENOG4108TU9	TRANSCRIPTIONal
AL543_14060	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AL543_14065	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AL543_14070	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AL543_14075	ENOG4105DUX	Transporter
AL543_14080	ENOG4105MDZ	Transcriptional activator rfaH
AL543_14085	ENOG4105CAQ	asparagine synthetase
AL543_14090	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AL543_14095	ENOG4105E2R	ROK family
AL543_14100	ENOG4105CE4	GlcNAc 6-P deacetylase
AL543_14105	ENOG4105CI1	PTS System
AL543_14110	ENOG4105CX6	glutaminyL-tRNA synthetase
AL543_14120	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AL543_14125	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AL543_14130	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AL543_14135	ENOG4108S3P	Sporulation domain protein
AL543_14140	ENOG4105E96	Colicin v production protein
AL543_14145	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AL543_14150	ENOG4105D3Y	Na H antiporter
AL543_14155	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AL543_14160	ENOG4105EIY	sodium-type flagellar protein motY
AL543_14165	ENOG4106WH9	Protein of unknown function (DUF2753)
AL543_14170	ENOG4108UYE	Lactoylglutathione lyase
AL543_14175	ENOG4105CSM	endonuclease III
AL543_14180	ENOG4105DZB	Electron transport complex
AL543_14185	ENOG4108UQQ	Electron transport complex
AL543_14190	ENOG4105D6A	Electron transport complex
AL543_14200	ENOG4108R3D	Electron transport complex
AL543_14210	ENOG4108RS6	transposase
AL543_14220	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AL543_14225	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AL543_14235	ENOG4105CHW	UPF0052 protein
AL543_14240	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AL543_14245	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AL543_14250	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AL543_14255	ENOG4105M00	molybdopterin converting factor, subunit 1
AL543_14260	ENOG4108ZAF	Molybdopterin
AL543_14275	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AL543_14290	ENOG4108I5U	Uridine phosphorylase
AL543_14300	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AL543_14305	ENOG4105D1F	ATP-binding protein
AL543_14310	ENOG4105DBI	uridine monophosphokinase
AL543_14315	ENOG4108GAE	asmA family
AL543_14320	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AL543_14330	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AL543_14335	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
AL543_14350	ENOG4105CHU	acetyl-coa acetyltransferase
AL543_14355	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AL543_14360	ENOG41069NU	Nitroreductase
AL543_14365	ENOG4105EJC	lysr family transcriptional regulator
AL543_14370	ENOG4105I93	response regulator
AL543_14380	ENOG4105WD1	Membrane
AL543_14385	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
AL543_14390	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AL543_14395	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AL543_14400	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AL543_14405	ENOG4105KRS	Proteinase inhibitor
AL543_14415	ENOG4105UBK	short-chain dehydrogenase reductase
AL543_14420	ENOG4105ERU	peptidase
AL543_14430	ENOG4108XM1	transcriptional regulator AsnC family
AL543_14435	ENOG4105C29	acyl-CoA thioesterase
AL543_14455	ENOG4105BZU	Histidine kinase
AL543_14485	ENOG4108NVR	Methyl-accepting chemotaxis
AL543_14495	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
AL543_14515	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
AL543_14520	ENOG4105J76	Periplasmic binding protein
AL543_14525	ENOG4105E0A	ABC, transporter
AL543_14555	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
AL543_14565	ENOG4107ZXU	DSBA oxidoreductase
AL543_14570	ENOG4107E54	Small Multidrug Resistance protein
AL543_14575	ENOG4105KPY	Small multidrug resistance protein
AL543_14580	ENOG4107Y2X	deaminase
AL543_14590	ENOG41082YX	Transcriptional regulator, arsr family
AL543_14595	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AL543_14610	ENOG4105E98	transcriptional regulator DeoR family
AL543_14615	ENOG410804X	Transcriptional regulator
AL543_14620	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
AL543_14625	ENOG4105E70	isomerase
AL543_14630	ENOG4108RG5	PTS system N-acetylgalactosamine-specific transporter subunit IIB
AL543_14635	ENOG4105ETZ	PTS System
AL543_14640	ENOG4105F3R	pts system mannose fructose sorbose family iid
AL543_14645	ENOG4108YTN	IIa component
AL543_14650	ENOG4105CE4	GlcNAc 6-P deacetylase
AL543_14655	ENOG4105D2N	Aldolase
AL543_14690	ENOG4108V1U	phospholipid-binding protein
AL543_14710	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AL543_14725	ENOG4107YTP	response regulator receiver protein
AL543_14735	ENOG4105BZU	Histidine kinase
AL543_14740	ENOG4105BZU	Histidine kinase
AL543_14745	ENOG4105BZU	Histidine kinase
AL543_14750	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AL543_14765	ENOG4107QSI	ABC, transporter
AL543_14770	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AL543_14775	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AL543_14780	ENOG4105C3U	ABC transporter
AL543_14785	ENOG4108JQ7	(ABC) transporter
AL543_14790	ENOG4105CHF	Glutathione S-transferase
AL543_14795	ENOG4108DNC	Involved in acetate metabolism (By similarity)
AL543_14800	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
AL543_14805	ENOG4105PQ6	UPF0208 membrane protein
AL543_14810	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AL543_14820	ENOG4105C7J	ABC transporter, permease
AL543_14825	ENOG4108JJB	ABC transporter
AL543_14830	ENOG4105BZU	Histidine kinase
AL543_14835	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AL543_14850	ENOG4105D1H	recombination factor protein RarA
AL543_14855	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AL543_14860	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AL543_14865	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AL543_14870	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AL543_14875	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AL543_14880	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AL543_14890	ENOG4105D0M	Protease HtpX homolog
AL543_14900	ENOG4107FW0	short-chain dehydrogenase reductase
AL543_14915	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AL543_14925	ENOG4105RHG	
AL543_14935	ENOG4107QTF	adenylosuccinate lyase
AL543_14940	ENOG41075W9	High frequency lysogenization protein HflD homolog
AL543_14945	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AL543_14950	ENOG4107RE1	Inosine-guanosine kinase
AL543_14960	ENOG4107S6Z	Na H antiporter
AL543_14965	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AL543_14970	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AL543_14975	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AL543_14980	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AL543_14985	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AL543_14990	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AL543_14995	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AL543_15000	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AL543_15005	ENOG4108R99	pseudouridine synthase
AL543_15015	ENOG4105VEQ	Cold shock protein
AL543_15020	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AL543_15025	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AL543_15035	ENOG41090BQ	Glutaredoxin
AL543_15045	ENOG4107QW4	alcohol dehydrogenase
AL543_15050	ENOG4106KNT	transcriptional regulator
AL543_15055	ENOG4105DY8	decarboxylase
AL543_15065	ENOG4105DWU	Membrane
AL543_15095	ENOG4105CUX	Signal transduction histidine kinase
AL543_15105	ENOG4105VNT	transposase (IS4 family) protein
AL543_15110	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AL543_15125	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AL543_15130	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AL543_15135	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AL543_15140	ENOG41081XQ	Conserved Protein
AL543_15145	ENOG4105C9M	aspartyl-trna synthetase
AL543_15150	ENOG4107104	thymidine kinase
AL543_15155	ENOG4105CK2	sodium dicarboxylate symporter
AL543_15160	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AL543_15165	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AL543_15170	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AL543_15175	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AL543_15180	ENOG4105DDQ	anthranilate synthase
AL543_15185	ENOG4105CRQ	synthase (Component I)
AL543_15195	ENOG4105DB7	PHP domain protein
AL543_15200	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AL543_15205	ENOG4105FE9	pseudouridine synthase
AL543_15210	ENOG4108JJ8	(ABC) transporter
AL543_15215	ENOG4108JJ9	ABC, transporter
AL543_15220	ENOG4105C3M	thioredoxin reductase
AL543_15230	ENOG4105C9B	Cysteine desulfurase
AL543_15235	ENOG4105BZU	Histidine kinase
AL543_15240	ENOG4107GZ4	SanA protein
AL543_15250	ENOG4107R1I	NAD-dependent malic enzyme
AL543_15260	ENOG4105C8V	SAICAR synthetase
AL543_15280	ENOG4108ZG0	Ompa motb domain protein
AL543_15295	ENOG4105CQB	FAD linked oxidase domain protein
AL543_15315	ENOG4105C84	Histidine ammonia-lyase
AL543_15320	ENOG4105CGP	Urocanate hydratase
AL543_15325	ENOG41088SP	formiminoglutamate hydrolase
AL543_15330	ENOG4105CI2	imidazolone-5-propionate hydrolase
AL543_15335	ENOG4105CZE	histidine utilization repressor
AL543_15350	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AL543_15360	ENOG41066DG	(EAL) domain protein
AL543_15365	ENOG4105CQ2	DNA polymerase
AL543_15370	ENOG4105WH1	Two component transcriptional regulator luxr family
AL543_15375	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AL543_15405	ENOG4108RS6	transposase
AL543_15420	ENOG4108MJ3	acetyltransferase
AL543_15425	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AL543_15430	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AL543_15435	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AL543_15455	ENOG4105FQ6	thiopurine methyltransferase
AL543_15470	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
AL543_15475	ENOG41067MG	lrgb family
AL543_15485	ENOG4105CJB	Exodeoxyribonuclease I
AL543_15490	ENOG4108ETY	sodium dicarboxylate symporter
AL543_15495	ENOG4105E0X	reductase
AL543_15500	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AL543_15505	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AL543_15510	ENOG4108YZT	Adenosylcobinamide kinase
AL543_15525	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
AL543_15530	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
AL543_15545	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_15570	ENOG4107QK7	reductase
AL543_15575	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AL543_15580	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AL543_15585	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AL543_15590	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AL543_15600	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
AL543_15610	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AL543_15615	ENOG4105DVI	reductase, NrfD
AL543_15620	ENOG4105DA4	cytochrome c-type biogenesis protein
AL543_15625	ENOG4107QX9	Thiol disulfide interChange protein
AL543_15630	ENOG4108DMF	Cytochrome C biogenesis protein
AL543_15640	ENOG4105VEQ	Cold shock protein
AL543_15645	ENOG4105C72	UPF0176 protein
AL543_15670	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AL543_15700	ENOG4105EAQ	(twin-arginine translocation) pathway signal
AL543_15705	ENOG4105C5X	domain protein
AL543_15720	ENOG4105CH5	extracellular solute-binding protein, family 7
AL543_15730	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AL543_15745	ENOG41067TZ	transcriptional regulator, MarR family
AL543_15750	ENOG4105C94	Transporter
AL543_15760	ENOG4105VZJ	PTS System
AL543_15770	ENOG4105VCP	PTS System
AL543_15775	ENOG4105F8D	glycoside hydrolase family 4
AL543_15780	ENOG410901P	UPF0249 protein
AL543_15785	ENOG4105ETE	Transcriptional regulator (LacI family
AL543_15790	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
AL543_15795	ENOG4105DJ9	glucan biosynthesis protein
AL543_15800	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_15815	ENOG4105CGF	Aromatic amino acid aminotransferase
AL543_15820	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AL543_15825	ENOG4108UW5	maltose o-acetyltransferase
AL543_15835	ENOG4105C5S	asparaginyl-tRNA synthetase
AL543_15840	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_15845	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AL543_15850	ENOG4105EJQ	L-serine dehydratase
AL543_15855	ENOG4105C44	Serine transporter
AL543_15860	ENOG4105P8F	nudix hydrolase
AL543_15865	ENOG4105CRQ	synthase (Component I)
AL543_15880	ENOG4105CM6	amino acid regulated cytosolic protein
AL543_15890	ENOG4108JU8	Transcriptional regulator
AL543_15895	ENOG4105D9U	N-acetyltransferase
AL543_15915	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AL543_15920	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_15925	ENOG4105C8P	)-transporter
AL543_15930	ENOG4105BZU	Histidine kinase
AL543_15935	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AL543_15945	ENOG4105RW8	MltA-interacting MipA family protein
AL543_15950	ENOG4105GR3	Histidine kinase
AL543_15955	ENOG4107EXC	regulatoR
AL543_15990	ENOG4105C2J	ABC transporter
AL543_15995	ENOG4107SDZ	Galactoside transport system permease protein mglC
AL543_16035	ENOG4105CR4	methylisocitrate lyase
AL543_16040	ENOG4105BZN	citrate synthase
AL543_16045	ENOG4108I0Z	Aconitate hydratase
AL543_16050	ENOG4105C7F	AcnD-accessory protein PrpF
AL543_16055	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AL543_16070	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AL543_16075	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
AL543_16080	ENOG4105F1J	Homogentisate 1,2-dioxygenase
AL543_16090	ENOG4108RXX	maleylacetoacetate isomerase
AL543_16095	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AL543_16100	ENOG4105BZU	Histidine kinase
AL543_16115	ENOG4106TD9	Diguanylate cyclase
AL543_16120	ENOG4105DR4	Methyltransferase
AL543_16130	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AL543_16135	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
AL543_16140	ENOG4108MN8	Membrane
AL543_16145	ENOG4105CDA	abc transporter atp-binding protein
AL543_16150	ENOG4105DRP	amino acid AbC transporter
AL543_16155	ENOG4105EZ7	amino acid ABC transporter
AL543_16160	ENOG4107QXX	ABC transporter
AL543_16170	ENOG410667J	hydrolase
AL543_16175	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AL543_16180	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AL543_16200	ENOG4105BZU	Histidine kinase
AL543_16210	ENOG4105BZU	Histidine kinase
AL543_16215	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AL543_16220	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AL543_16230	ENOG4105BZU	Histidine kinase
AL543_16260	ENOG4105CQ7	ATP-dependent helicase
AL543_16270	ENOG4106032	Glutathionylspermidine synthase
AL543_16305	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AL543_16310	ENOG4105R8A	Heat shock protein
AL543_16315	ENOG4105EJC	lysr family transcriptional regulator
AL543_16320	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AL543_16325	ENOG4105KPY	Small multidrug resistance protein
AL543_16330	ENOG4108NVR	Methyl-accepting chemotaxis
AL543_16335	ENOG4107SDU	Methyl-accepting chemotaxis
AL543_16340	ENOG4105C1J	atp-dependent rna helicase
AL543_16360	ENOG4105DDR	sarcosine oxidase (Beta subunit)
AL543_16395	ENOG4107UWN	reductase
AL543_16400	ENOG4108V8F	Transcriptional regulator, MarR family
AL543_16405	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AL543_16425	ENOG4105CNV	Aldolase
AL543_16440	ENOG4105C26	Dehydrogenase
AL543_16455	ENOG4107THI	3,4-dihydroxyphenylacetate 2,3-dioxygenase
AL543_16460	ENOG4105C26	Dehydrogenase
AL543_16475	ENOG4105CTD	carboxy-peptidase
AL543_16480	ENOG4108WC9	type VI secretion system effector, hcp1 family
AL543_16485	ENOG4105CS6	Rhs element vgr protein
AL543_16505	ENOG410829K	Lysine exporter protein (Lyse ygga)
AL543_16510	ENOG4105BZG	amino acid carrier protein
AL543_16525	ENOG4108KHP	Diguanylate cyclase
AL543_16530	ENOG4105BZU	Histidine kinase
AL543_16545	ENOG4105C26	Dehydrogenase
AL543_16550	ENOG4107RUE	extracellular solute-binding protein family 1
AL543_16555	ENOG4107RUE	extracellular solute-binding protein family 1
AL543_16560	ENOG4105D38	putrescine abc transporter
AL543_16565	ENOG4105F38	ABC transporter, permease
AL543_16570	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AL543_16595	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AL543_16600	ENOG4105Q9Y	Universal stress protein
AL543_16605	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
AL543_16620	ENOG4105C59	p-type ATPase
AL543_16630	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
AL543_16645	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AL543_16660	ENOG4105BZU	Histidine kinase
AL543_16685	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
AL543_16690	ENOG4105DAN	ATP-dependent protease
AL543_16695	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AL543_16710	ENOG4105C5H	ABC transporter
AL543_16720	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AL543_16725	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
AL543_16730	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AL543_16735	ENOG4105C7I	Dehydrogenase
AL543_16745	ENOG4105CD8	aminopeptidase N
AL543_16755	ENOG4105CN1	protease
AL543_16760	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
AL543_16765	ENOG4108ZGC	gaf domain protein
AL543_16775	ENOG4105H2K	paraquat-inducible protein a
AL543_16780	ENOG4105DY2	Paraquat-inducible protein b
AL543_16785	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AL543_16790	ENOG4105QNR	S1 RNA binding domain protein
AL543_16805	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AL543_16815	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AL543_16840	ENOG4105QAX	Iron-sulfur
AL543_16845	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AL543_16855	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AL543_16875	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AL543_16880	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_16885	ENOG4105C5H	ABC transporter
AL543_16890	ENOG4105BZU	Histidine kinase
AL543_16895	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AL543_16905	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
AL543_16910	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AL543_16915	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AL543_16920	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AL543_16930	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
AL543_16935	ENOG4106IUH	DTW domain containing protein
AL543_16945	ENOG4108N3W	hemolysin secretion protein
AL543_16950	ENOG4108QBX	(LipO)protein
AL543_16960	ENOG4105FGM	Fructosamine kinase
AL543_16970	ENOG4107QI1	Mate efflux family protein
AL543_16995	ENOG4109015	Biopolymer transport protein exbD tolR
AL543_17020	ENOG4105BZ7	extracellular solute-binding protein family 1
AL543_17030	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
AL543_17035	ENOG4108IJ9	(ABC) transporter
AL543_17040	ENOG4105E98	transcriptional regulator DeoR family
AL543_17045	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
AL543_17050	ENOG4105XEP	YhcH YjgK YiaL family protein
AL543_17060	ENOG4105DDV	Transcriptional regulator (LacI family
AL543_17065	ENOG4105CS2	ec 3.2.1.21
AL543_17070	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AL543_17095	ENOG4107RBB	ABC transporter, permease
AL543_17100	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AL543_17105	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AL543_17115	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AL543_17120	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
AL543_17125	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
AL543_17130	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AL543_17135	ENOG4105C9B	Cysteine desulfurase
AL543_17140	ENOG4105JRK	feS assembly protein SufD
AL543_17145	ENOG4105C3K	feS assembly ATPase SufC
AL543_17150	ENOG4105DIW	FeS assembly protein SUFB
AL543_17155	ENOG4108Z4V	iron-sulfur cluster assembly
AL543_17165	ENOG4105C9Q	fumarate hydratase class II
AL543_17185	ENOG4105V0I	UPF0267 protein
AL543_17190	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AL543_17200	ENOG4105CH6	catalase
AL543_17210	ENOG4105F88	accessory colonization factor AcfD
AL543_17220	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
AL543_17225	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AL543_17230	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
AL543_17250	ENOG4105BZU	Histidine kinase
AL543_17265	ENOG4107R88	Chemotaxis protein (CheV)
AL543_17275	ENOG4106YYS	transcriptional regulatory protein
AL543_17280	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AL543_17295	ENOG4107V40	secretion protein, HlyD family
AL543_17315	ENOG4105CVG	Homoserine O-transsuccinylase
AL543_17320	ENOG41090FY	type IV pilus biogenesis stability protein PilW
AL543_17335	ENOG4108VKG	metal-dependent hydrolase
AL543_17345	ENOG4105F04	LysR family Transcriptional regulator
AL543_17365	ENOG4105DFG	type I secretion outer membrane protein
AL543_17370	ENOG4105CDV	Ompa motb domain protein
AL543_17375	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
AL543_17380	ENOG4105E3Q	saccharopine dehydrogenase
AL543_17395	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AL543_17410	ENOG4108I0Y	(ABC) transporter
AL543_17415	ENOG4107QI1	Mate efflux family protein
AL543_17420	ENOG4105CGD	Nad-dependent epimerase dehydratase
AL543_17430	ENOG4105C2C	drug resistance transporter, Bcr CflA
AL543_17435	ENOG4105I08	Pseudouridine synthase
AL543_17440	ENOG4105CFI	type iii restriction protein res subunit
AL543_17450	ENOG4105ETX	regulatoR
AL543_17460	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AL543_17510	ENOG4105BZS	acriflavin resistance protein
AL543_17535	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AL543_17555	ENOG4105KXC	Collagenase
AL543_17565	ENOG4105BZU	Histidine kinase
AL543_17570	ENOG4105BZU	Histidine kinase
AL543_17575	ENOG4105CJW	magnesium transporter
AL543_17585	ENOG4105C44	Serine transporter
AL543_17595	ENOG4105CJ1	ABC, transporter
AL543_17600	ENOG4107QWP	ABC-2 type transporter
AL543_17610	ENOG4105XZD	Fe-S protein
AL543_17620	ENOG4105VNH	ABC transporter solute-binding protein
AL543_17625	ENOG4105CXZ	ABC transporter, permease
AL543_17630	ENOG4108VGW	abc transporter atp-binding protein
AL543_17635	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
AL543_17640	ENOG4108W1A	pseudouridine synthase
AL543_17645	ENOG4105C8J	)-transporter
AL543_17655	ENOG4105C28	cystathionine
AL543_17660	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AL543_17665	ENOG4107R37	Glutamate dehydrogenase
AL543_17680	ENOG41087YS	Phage shock protein A
AL543_17685	ENOG4105E51	psp operon transcriptional activator
AL543_17690	ENOG4108J59	Extracellular solute-binding protein, family 5
AL543_17695	ENOG4108I5W	peptide transport system, permease protein
AL543_17700	ENOG4108EU3	peptide transport system, permease
AL543_17705	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
AL543_17710	ENOG4108JQ2	peptide transport system atp-binding protein
AL543_17725	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AL543_17745	ENOG4108RS6	transposase
AL543_17750	ENOG4108RS6	transposase
AL543_17755	ENOG4107QY8	reductase
AL543_17775	ENOG4105TMB	Formate nitrite transporter
AL543_17785	ENOG4108535	NAD dependent epimerase/dehydratase family
AL543_17790	ENOG4105GFG	DUF218 domain
AL543_17800	ENOG4105BZU	Histidine kinase
AL543_17805	ENOG4107835	probably involved in intracellular septation (By similarity)
AL543_17810	ENOG4105NAU	thioesterase Superfamily protein
AL543_17815	ENOG4105K9H	YciI-like protein
AL543_17825	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AL543_17830	ENOG4105DZ2	Transcriptional regulator
AL543_17850	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
AL543_17855	ENOG4105CCT	upf0313 protein
AL543_17860	ENOG4108VP3	Lysine exporter protein (LysE YggA)
AL543_17865	ENOG4105EW9	transcriptional regulator AsnC family
AL543_17870	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
AL543_17875	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
AL543_17880	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
AL543_17885	ENOG4106371	Methyltransferase
AL543_17890	ENOG4107S90	membrAne
AL543_17895	ENOG4106WF9	DNA-binding transcriptional regulator TorR
AL543_17900	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AL543_17905	ENOG4105ETE	Transcriptional regulator (LacI family
AL543_17910	ENOG4105HP8	regulator of competence-specific genes
AL543_17930	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AL543_17935	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AL543_17940	ENOG4108RS6	transposase
AL543_17945	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AL543_17950	ENOG4105RKX	Protein of unknown function (DUF2498)
AL543_17955	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AL543_17965	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AL543_17970	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AL543_17975	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AL543_17985	ENOG4107QPN	acyl-Coa dehydrogenase
AL543_17990	ENOG41067SE	Tetr family transcriptional regulator
AL543_18000	ENOG4105MTM	Protein of unknown function (DUF1496)
AL543_18005	ENOG4105C26	Dehydrogenase
AL543_18010	ENOG4108R86	Transcriptional regulator
AL543_18015	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AL543_18030	ENOG4105BZU	Histidine kinase
AL543_18040	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
AL543_18045	ENOG4105CEE	C4-dicarboxylate transporter
AL543_18140	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
AL543_18155	ENOG4105C4X	radical SAM domain protein
AL543_18160	ENOG4106KR7	LysR family Transcriptional regulator
AL543_18195	ENOG4105DM4	PTS System
AL543_18200	ENOG4105CWX	Alpha-1,2-mannosidase
AL543_18210	ENOG4105CWX	Alpha-1,2-mannosidase
AL543_18215	ENOG4105CWX	Alpha-1,2-mannosidase
AL543_18225	ENOG4105CWX	Alpha-1,2-mannosidase
AL543_18235	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AL543_18240	ENOG4105DM4	PTS System
AL543_18245	ENOG4108YRF	PTS System
AL543_18255	ENOG4106R3P	AraC family transcriptional regulator
AL543_18260	ENOG4105DM4	PTS System
AL543_18265	ENOG4105EIP	mannose-6-phosphate isomerase
AL543_18270	ENOG4108RNS	Exports L-alanine (By similarity)
AL543_18275	ENOG4105BZU	Histidine kinase
AL543_18285	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AL543_18295	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AL543_18300	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AL543_18310	ENOG4105M8F	Biopolymer transport protein exbD tolR
AL543_18315	ENOG4105E02	MotA TolQ exbB proton channel
AL543_18320	ENOG4107YD3	Thioesterase
AL543_18335	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AL543_18340	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AL543_18345	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AL543_18350	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AL543_18355	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AL543_18360	ENOG4105C8N	cysteinyl-tRNA synthetase
AL543_18365	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AL543_18370	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AL543_18375	ENOG4105D58	Diguanylate phosphodiesterase
AL543_18400	ENOG4105DVT	helicase
AL543_18405	ENOG4105EJ9	Membrane
AL543_18410	ENOG4108URS	primosomal replication protein n''
AL543_18415	ENOG4106428	Protein of unknown function (DUF2496)
AL543_18420	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_18425	ENOG4105CGK	Exodeoxyribonuclease III
AL543_18430	ENOG4106YG3	ABC transporter
AL543_18435	ENOG4105DSP	amino acid AbC transporter
AL543_18440	ENOG4105E89	ABC transporter
AL543_18445	ENOG4108JEH	abc transporter atp-binding protein
AL543_18455	ENOG4105C6N	Formate acetyltransferase
AL543_18465	ENOG4108N3W	hemolysin secretion protein
AL543_18470	ENOG4105F1A	Pyruvate formate-lyase
AL543_18480	ENOG4105XWI	UPF0304 protein
AL543_18485	ENOG4105CYN	Serine protein kinase
AL543_18490	ENOG4106AKX	UPF0229 protein
AL543_18495	ENOG4105ED1	spovr family
AL543_18500	ENOG4105CI1	PTS System
AL543_18505	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
AL543_18510	ENOG4105DHQ	Histidine kinase
AL543_18520	ENOG4105VNT	transposase (IS4 family) protein
AL543_18525	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AL543_18535	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AL543_18540	ENOG4105BZ1	(ABC) transporter
AL543_18545	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AL543_18555	ENOG4105D60	lipoprotein releasing system transmembrane protein
AL543_18560	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AL543_18565	ENOG4105D60	lipoprotein releasing system transmembrane protein
AL543_18575	ENOG4108JA2	transcriptioN-repair coupling factor
AL543_18590	ENOG4105CEP	NADH dehydrogenase
AL543_18620	ENOG4105K59	histidine triad (HIT) protein
AL543_18625	ENOG4108NVR	Methyl-accepting chemotaxis
AL543_18635	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
AL543_18640	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AL543_18645	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AL543_18650	ENOG4105CNU	cell division protein FtsK
AL543_18655	ENOG4105EW9	transcriptional regulator AsnC family
AL543_18660	ENOG4105DCF	alanine dehydrogenase
AL543_18670	ENOG4107R11	Transcriptional regulator
AL543_18680	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
AL543_18685	ENOG4108RS6	transposase
AL543_18700	ENOG4108JQ7	(ABC) transporter
AL543_18715	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AL543_18720	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AL543_18750	ENOG4107V1M	polysaccharide export protein
AL543_18765	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AL543_18775	ENOG4107TYR	Glycosyl Transferase
AL543_18795	ENOG4108UW5	maltose o-acetyltransferase
AL543_18810	ENOG4105CPK	Glycosyl transferase (Group 1
AL543_18815	ENOG4105CND	Glycosyl transferase, family 2
AL543_18830	ENOG4105BZU	Histidine kinase
AL543_18835	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AL543_18840	ENOG4105CFV	Tetratricopeptide repeat protein
AL543_18845	ENOG4105Q4A	inner membrane protein yciS
AL543_18850	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AL543_18855	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AL543_18860	ENOG4105CAT	Cytidine monophosphate kinase
AL543_18865	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AL543_18870	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AL543_18875	ENOG4105K70	DNA-binding protein
AL543_18880	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AL543_18885	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AL543_18890	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AL543_18895	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AL543_18910	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AL543_18915	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AL543_18920	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
AL543_18925	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
AL543_18930	ENOG4105CNG	UPF0061 protein
AL543_18945	ENOG4105BZU	Histidine kinase
AL543_18955	ENOG4108HPI	phosphatidate Cytidylyltransferase
AL543_18970	ENOG4106CKV	Pap2 superfamily protein
AL543_18985	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AL543_19035	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AL543_19045	ENOG410662T	chitinase
AL543_19050	ENOG4105D9N	nucleoside
AL543_19055	ENOG4105JQN	Transcriptional regulator
AL543_19060	ENOG4105CVE	Lytic murein transglycosylase
AL543_19065	ENOG4105VNG	YcgL domain-containing protein
AL543_19070	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AL543_19075	ENOG4107QMS	site-determining protein
AL543_19080	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AL543_19105	ENOG4107S74	Lysophospholipid transporter LplT
AL543_19110	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_19115	ENOG4108JCI	Transcriptional regulator
AL543_19120	ENOG4105DKK	Benzoate
AL543_19125	ENOG4105CEY	Amp-dependent synthetase and ligase
AL543_19130	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
AL543_19135	ENOG4108IPT	Naphthoate synthase
AL543_19140	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
AL543_19145	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AL543_19150	ENOG4105E4F	Isochorismate synthase
AL543_19155	ENOG4105CHM	Aminotransferase
AL543_19160	ENOG4105DK2	UPF0207 protein
AL543_19165	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AL543_19175	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
AL543_19185	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AL543_19190	ENOG4105CEY	Amp-dependent synthetase and ligase
AL543_19195	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AL543_19210	ENOG41072GX	Peptidase M22 Glycoprotease
AL543_19215	ENOG4105DVT	helicase
AL543_19225	ENOG4105CIY	formyltetrahydrofolate deformylase
AL543_19230	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AL543_19235	ENOG4105D07	Signal peptide peptidase, SppA
AL543_19240	ENOG4105HDK	L-asparaginase
AL543_19245	ENOG4105VUT	cytoplasmic protein
AL543_19255	ENOG4105E0X	reductase
AL543_19260	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AL543_19265	ENOG4105DSB	aldose 1-epimerase
AL543_19275	ENOG4105DHI	Methyltransferase
AL543_19305	ENOG4107R88	Chemotaxis protein (CheV)
AL543_19310	ENOG4105DAG	ROK family
AL543_19315	ENOG4105CA9	Pyruvate kinase
AL543_19320	ENOG4108NRW	Phospholipase, patatin family
AL543_19330	ENOG4105C8J	)-transporter
AL543_19340	ENOG4105CI1	PTS System
AL543_19345	ENOG4105F8V	Hydrolase, tatD family
AL543_19350	ENOG4107QRG	dna polymerase iii
AL543_19355	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AL543_19360	ENOG4105HHA	aminodeoxychorismate lyase
AL543_19365	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
AL543_19370	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AL543_19375	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AL543_19380	ENOG4105CHR	reductase
AL543_19385	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AL543_19390	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AL543_19395	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AL543_19400	ENOG4105VGS	50s ribosomal protein l32
AL543_19405	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
AL543_19410	ENOG4108UHJ	MAF-like protein
AL543_19415	ENOG4105EI2	Pseudouridine synthase
AL543_19425	ENOG4105C03	ribonuclease
AL543_19430	ENOG4105CHH	sulfate transporter
AL543_19440	ENOG4105VNT	transposase (IS4 family) protein
AL543_19445	ENOG4108EKI	Dehydrogenase
AL543_19450	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AL543_19455	ENOG4105EYW	Ion transport protein
AL543_19460	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AL543_19465	ENOG4105DFD	Na H antiporter
AL543_19475	ENOG4106V8H	Nucleoid-associated protein
AL543_19485	ENOG4105E68	Sulfatase
AL543_19515	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
AL543_19530	ENOG4105DGU	Histone deacetylase
AL543_19535	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AL543_19540	ENOG4105M2J	Glutaredoxin
AL543_19545	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AL543_19560	ENOG410903C	(LipO)protein
AL543_19570	ENOG4105KWW	Biogenesis protein
AL543_19575	ENOG4107QX9	Thiol disulfide interChange protein
AL543_19580	ENOG4105DA4	cytochrome c-type biogenesis protein
AL543_19585	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AL543_19595	ENOG41060IM	Heme exporter protein
AL543_19600	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AL543_19605	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AL543_19615	ENOG4108V3W	Chemotaxis protein, CheW
AL543_19625	ENOG4107QJE	Chromosome Partitioning Protein
AL543_19630	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AL543_19635	ENOG4105CBS	Chea signal transduction histidine kinase
AL543_19640	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
AL543_19645	ENOG4108VYJ	response regulator receiver protein
AL543_19650	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AL543_19655	ENOG4107R21	site-determining protein
AL543_19660	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AL543_19665	ENOG4105D7B	Flagellar biosynthesis protein flha
AL543_19670	ENOG4108BY2	phosphohistidine phosphatase
AL543_19675	ENOG4108JQM	Insulinase (Peptidase family M16)
AL543_19685	ENOG4105C75	arginyL-tRNA synthetase
AL543_19705	ENOG4105XFK	Ferrous iron transport protein A
AL543_19710	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
AL543_19715	ENOG4105NXV	High-affinity zinc uptake system protein
AL543_19720	ENOG4105FDK	ABC transporter
AL543_19725	ENOG4105FAV	ABC, transporter
AL543_19730	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AL543_19735	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AL543_19740	ENOG4105C7S	Dehydrogenase
AL543_19745	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AL543_19750	ENOG4105E33	succinate dehydrogenase
AL543_19755	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AL543_19760	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
AL543_19765	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
AL543_19770	ENOG4105BZN	citrate synthase
AL543_19775	ENOG4107QNR	UPF0135 protein
AL543_19785	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
AL543_19790	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
AL543_19795	ENOG4105EV9	Alpha Beta Hydrolase
AL543_19805	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
AL543_19810	ENOG41067MG	lrgb family
AL543_19815	ENOG4105VAW	lrga family
AL543_19820	ENOG4105CMU	LysR family (Transcriptional regulator
AL543_19830	ENOG41090R7	Ferric uptake
AL543_19835	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AL543_19840	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
AL543_19845	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AL543_19850	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AL543_19855	ENOG4105Q8W	reductase
AL543_19860	ENOG4105MH2	YfcL protein
AL543_19865	ENOG4108BPE	-transporting atpase
AL543_19870	ENOG4105EN6	Membrane
AL543_19875	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AL543_19885	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AL543_19895	ENOG4105D00	flagellar biosynthetic protein flhB
AL543_19900	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AL543_19905	ENOG4105VS8	Flagellar biosynthetic protein fliq
AL543_19910	ENOG4105CN7	Flagellar biosynthetic protein FliP
AL543_19915	ENOG4105VTB	flagellar biosynthesis protein fliO
AL543_19920	ENOG4105DD5	Flagellar motor switch protein
AL543_19925	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AL543_19945	ENOG4108JIR	Flagellum-specific ATP synthase
AL543_19950	ENOG4105W2B	Flagellar assembly protein
AL543_19955	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AL543_19960	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AL543_19965	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AL543_19970	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AL543_19975	ENOG4105BZU	Histidine kinase
AL543_19980	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AL543_19985	ENOG4105MQ3	flagellar protein FliS
AL543_19995	ENOG4107W9T	flagellar hook-associated
AL543_20000	ENOG41063QE	flagellar protein FlaG
AL543_20005	ENOG4105I03	Flagellin
AL543_20010	ENOG4105I03	Flagellin
AL543_20015	ENOG4105I03	Flagellin
AL543_20020	ENOG4105EZR	dyp-type peroxidase family protein
AL543_20025	ENOG4105QZU	Inner membrane protein YfeZ
AL543_20040	ENOG4105KUZ	arsenate reductase
AL543_20045	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AL543_20060	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AL543_20065	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AL543_20075	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL543_20080	ENOG4105C8Q	Methyl-accepting chemotaxis
AL543_20095	ENOG4105ERG	peptidase m48, ste24p
AL543_20100	ENOG4105K89	arsenate reductase
AL543_20105	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AL543_20120	ENOG4105C2W	permease
AL543_20125	ENOG4108Z66	YbaK ebsC protein
AL543_20130	ENOG4105CGH	5'-nucleotidase
AL543_20135	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AL543_20140	ENOG41063JG	Transcriptional regulator
AL543_20145	ENOG4108YY7	Invasion gene expression up-regulator SirB
AL543_20150	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AL543_20155	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AL543_20160	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AL543_20165	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
AL543_20170	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AL543_20175	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AL543_20180	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AL543_20185	ENOG4105C3G	gtp-binding protein
AL543_20270	ENOG4105I03	Flagellin
AL543_20280	ENOG4105I03	Flagellin
AL543_20295	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AL543_20300	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AL543_20305	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AL543_20310	ENOG4105CGA	flagellar basal-body rod protein FlgG
AL543_20315	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AL543_20320	ENOG4105BZE	flagellar hook protein, FlgE
AL543_20325	ENOG4105W00	Flagellar hook capping protein
AL543_20330	ENOG4108ZC9	flagellar basal-body rod protein flgc
AL543_20335	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AL543_20350	ENOG4105BZU	Histidine kinase
AL543_20355	ENOG4107R88	Chemotaxis protein (CheV)
AL543_20400	ENOG4105UYK	outer membrane protein a
AL543_20405	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AL543_20410	ENOG4105C59	p-type ATPase
AL543_20420	ENOG4105E2D	ec 3.2.1.52
AL543_20440	ENOG4108DG9	Smr protein MutS2
AL543_20445	ENOG4105FE9	pseudouridine synthase
AL543_20450	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
AL543_20455	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AL543_20460	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AL543_20465	ENOG4105E7A	Glutamine amidotransferase
AL543_20470	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AL543_20475	ENOG4107QPN	acyl-Coa dehydrogenase
AL543_20480	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AL543_20485	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AL543_20500	ENOG4105E18	UPF0276 protein
AL543_20520	ENOG4108JDX	DNA polymerase iii, epsilon subunit
AL543_20525	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AL543_20530	ENOG4105D1A	Methyltransferase
AL543_20535	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AL543_20540	ENOG4105E9H	Lytic Murein transglycosylase
AL543_20550	ENOG4108YZA	Nitrogen regulatory protein pii
AL543_20560	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AL543_20565	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AL543_20575	ENOG4105CPQ	Dehydrogenase
AL543_20585	ENOG4107R08	Integrase
AL543_20785	ENOG4105YGK	Pfam:UPF0157
AL543_21020	ENOG4105YGK	Pfam:UPF0157
AL543_21225	ENOG4105YGK	Pfam:UPF0157