locus-tag	class	description
KW548_00020	COG2927	DNA polymerase III (CHI subunit)
KW548_00080	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KW548_00085	COG0251	oxidation-reduction process
KW548_00095	COG0039	L-malate dehydrogenase activity
KW548_00100	COG1438	arginine binding
KW548_00105	COG2358	TRAP transporter, solute receptor (TAXI family
KW548_00140	COG0312	modulator of DNA gyrase
KW548_00145	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KW548_00150	COG3164	Protein of unknown function
KW548_00160	COG0424	maF-like protein
KW548_00165	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KW548_00170	COG1792	Involved in formation and maintenance of cell shape
KW548_00210	COG2165	general secretion pathway protein
KW548_00215	COG2165	general secretion pathway protein
KW548_00225	COG1459	type II secretion system
KW548_00240	COG3267	Type II secretory pathway component ExeA
KW548_00240	COG3409	Peptidoglycan-binding domain 1 protein
KW548_00270	COG0629	single-stranded DNA binding
KW548_00295	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KW548_00300	COG0527	aspartate kinase activity
KW548_00305	COG0312	modulator of DNA gyrase
KW548_00310	COG3028	Belongs to the UPF0307 family
KW548_00315	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
KW548_00320	COG1178	ABC-type Fe3 transport system permease component
KW548_00325	COG4143	(ABC) transporter
KW548_00330	COG0163	prenyltransferase activity
KW548_00335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KW548_00345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KW548_00350	COG2105	PFAM AIG2 family protein
KW548_00365	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KW548_00375	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
KW548_00390	COG1136	(ABC) transporter
KW548_00415	COG0432	Pfam Uncharacterised protein family UPF0047
KW548_00420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KW548_00425	COG0305	Participates in initiation and elongation during chromosome replication
KW548_00445	COG0360	Binds together with S18 to 16S ribosomal RNA
KW548_00455	COG2906	2 iron, 2 sulfur cluster binding
KW548_00460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KW548_00465	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KW548_00470	COG0049	tRNA binding
KW548_00485	COG2923	Belongs to the DsrF TusC family
KW548_00490	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KW548_00495	COG2964	Protein conserved in bacteria
KW548_00500	COG0545	Peptidyl-prolyl cis-trans isomerase
KW548_00510	COG2900	Belongs to the SlyX family
KW548_00515	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
KW548_00520	COG0330	HflC and HflK could
KW548_00525	COG0330	HflC and HflK could
KW548_00530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KW548_00545	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KW548_00555	COG0802	atpase or kinase
KW548_00560	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KW548_00615	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KW548_00620	COG1162	GTPase activity
KW548_00645	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KW548_00650	COG4942	peptidase
KW548_00670	COG2816	NAD+ diphosphatase activity
KW548_00675	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
KW548_00685	COG0085	RNA polymerase activity
KW548_00695	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KW548_00710	COG0250	Participates in transcription elongation, termination and antitermination
KW548_00715	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KW548_00720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KW548_00745	COG1072	(Pantothenic acid kinase))
KW548_00775	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KW548_00780	COG0511	ligase activity, forming carbon-carbon bonds
KW548_00785	COG0439	Biotin carboxylase
KW548_00790	COG2264	protein methyltransferase activity
KW548_00795	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KW548_00800	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KW548_00805	COG2199	diguanylate cyclase activity
KW548_00810	COG0789	Transcriptional regulator
KW548_00820	COG0151	Belongs to the GarS family
KW548_00835	COG1253	flavin adenine dinucleotide binding
KW548_00845	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KW548_00850	COG1573	uracil-dna glycosylase
KW548_00860	COG1695	Transcriptional regulator
KW548_00865	COG1045	serine acetyltransferase
KW548_00880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KW548_00915	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KW548_00920	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KW548_00925	COG1053	succinate dehydrogenase
KW548_00930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KW548_00940	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
KW548_00955	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KW548_00960	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KW548_00965	COG1609	Transcriptional regulator
KW548_00970	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KW548_00980	COG0281	malic enzyme
KW548_00990	COG0626	cystathionine gamma-synthase activity
KW548_01000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KW548_01005	COG3074	FtsZ-dependent cytokinesis
KW548_01010	COG1494	fructose-1,6-bisphosphatase
KW548_01050	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KW548_01055	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KW548_01055	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KW548_01060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KW548_01070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KW548_01075	COG2030	dehydratase
KW548_01085	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KW548_01105	COG1086	Polysaccharide biosynthesis protein
KW548_01120	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KW548_01125	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KW548_01165	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KW548_01185	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KW548_01195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KW548_01225	COG0859	PFAM glycosyl transferase family 9
KW548_01240	COG1519	Transferase
KW548_01270	COG3642	lipopolysaccharide core region biosynthetic process
KW548_01275	COG0859	PFAM glycosyl transferase family 9
KW548_01280	COG0463	Glycosyl transferase, family 2
KW548_01285	COG0859	PFAM glycosyl transferase family 9
KW548_01290	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KW548_01310	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KW548_01320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KW548_01325	COG1309	transcriptional regulator
KW548_01330	COG1560	Kdo2-lipid A biosynthetic process
KW548_01340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KW548_01345	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KW548_01350	COG1561	YicC-like family, N-terminal region
KW548_01425	COG2252	PERMEase
KW548_01435	COG0848	biopolymer transport protein
KW548_01465	COG1595	DNA-templated transcription, initiation
KW548_01470	COG0194	GDP metabolic process
KW548_01475	COG1758	RNA polymerase activity
KW548_01480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KW548_01485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KW548_01500	COG0494	nUDIX hydrolase
KW548_01515	COG0596	Alpha beta hydrolase
KW548_01525	COG2183	response to ionizing radiation
KW548_01555	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KW548_01560	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
KW548_01565	COG3156	type II secretion system protein K
KW548_01570	COG4795	General secretion pathway protein
KW548_01575	COG2165	general secretion pathway protein
KW548_01580	COG2165	general secretion pathway protein
KW548_01585	COG2165	general secretion pathway protein
KW548_01590	COG1459	type II secretion system
KW548_01595	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KW548_01605	COG3031	protein transport across the cell outer membrane
KW548_01610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KW548_01620	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KW548_01630	COG0456	acetyltransferase
KW548_01635	COG1490	D-aminoacyl-tRNA deacylase activity
KW548_01640	COG1295	ribonuclease BN
KW548_01650	COG1217	gtp-binding protein TYPA
KW548_01655	COG0174	glutamine synthetase
KW548_01665	COG2204	response regulator
KW548_01670	COG3300	MHYT domain
KW548_01670	COG5001	Diguanylate cyclase
KW548_01675	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KW548_01715	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KW548_01730	COG0408	coproporphyrinogen oxidase activity
KW548_01740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KW548_01745	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KW548_01750	COG0551	DNA topoisomerase type I activity
KW548_01755	COG2922	Belongs to the Smg family
KW548_01775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KW548_01775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KW548_01780	COG0569	domain protein
KW548_01785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KW548_01795	COG1272	protein, Hemolysin III
KW548_01800	COG4326	sporulation control protein
KW548_01840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KW548_01845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KW548_01850	COG0204	Acyl-transferase
KW548_01870	COG3978	acetolactate synthase activity
KW548_01875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KW548_01880	COG0129	dihydroxy-acid dehydratase activity
KW548_01905	COG0425	Belongs to the sulfur carrier protein TusA family
KW548_01915	COG2119	membrane
KW548_01920	COG0752	glycyl-tRNA synthetase alpha subunit
KW548_01925	COG0751	glycine-tRNA ligase activity
KW548_01930	COG3977	Valine--pyruvate aminotransferase
KW548_01935	COG0071	Belongs to the small heat shock protein (HSP20) family
KW548_01945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KW548_01950	COG0592	DNA-directed DNA polymerase activity
KW548_01970	COG1126	abc transporter atp-binding protein
KW548_01975	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KW548_01995	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KW548_02000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KW548_02010	COG0357	Ribosomal RNA small subunit methyltransferase G
KW548_02015	COG1192	Involved in chromosome partitioning
KW548_02020	COG1475	DNA binding
KW548_02025	COG3312	ion transport
KW548_02045	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KW548_02055	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KW548_02060	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KW548_02065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KW548_02075	COG0765	amino acid transport
KW548_02090	COG0583	DNA-binding transcription factor activity
KW548_02095	COG0183	Belongs to the thiolase family
KW548_02110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KW548_02170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KW548_02185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KW548_02195	COG2022	thiamine diphosphate biosynthetic process
KW548_02205	COG0006	proline dipeptidase activity
KW548_02205	COG0006	proline dipeptidase activity
KW548_02225	COG1522	sequence-specific DNA binding
KW548_02230	COG5001	Diguanylate cyclase
KW548_02230	COG5002	protein histidine kinase activity
KW548_02235	COG0742	ribosomal rna small subunit methyltransferase
KW548_02250	COG0589	response to stress
KW548_02255	COG1528	Iron-storage protein
KW548_02265	COG2081	HI0933 family
KW548_02290	COG1639	'signal transduction protein
KW548_02300	COG1322	Protein conserved in bacteria
KW548_02305	COG2226	methyltransferase
KW548_02325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KW548_02330	COG0805	protein transport
KW548_02335	COG0084	hydrolase, TatD family'
KW548_02380	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KW548_02385	COG0583	DNA-binding transcription factor activity
KW548_02390	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KW548_02395	COG2960	long-chain fatty acid transporting porin activity
KW548_02405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW548_02410	COG1309	transcriptional regulator
KW548_02455	COG0747	negative chemotaxis
KW548_02460	COG0601	transmembrane transport
KW548_02465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KW548_02480	COG0745	RESPONSE REGULATOR receiver
KW548_02495	COG0477	Major facilitator Superfamily
KW548_02510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KW548_02520	COG0339	signal peptide processing
KW548_02535	COG3220	belongs to the UPF0276 family
KW548_02545	COG0210	DNA helicase
KW548_02550	COG0405	Gamma-glutamyltransferase
KW548_02565	COG2962	Rard protein
KW548_02570	COG0514	ATP-dependent DNA helicase (RecQ)
KW548_02580	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KW548_02585	COG0248	Ppx GppA phosphatase
KW548_02595	COG3118	belongs to the thioredoxin family
KW548_02610	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KW548_02675	COG2959	enzyme of heme biosynthesis
KW548_02680	COG1587	Uroporphyrinogen-III synthase
KW548_02690	COG3072	Adenylate cyclase
KW548_02695	COG1965	Belongs to the frataxin family
KW548_02705	COG0019	diaminopimelate decarboxylase activity
KW548_02710	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KW548_02720	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KW548_02725	COG1011	Hydrolase
KW548_02730	COG3148	PFAM DTW domain containing protein
KW548_02745	COG0561	phosphatase activity
KW548_02755	COG1280	lysine exporter protein (LysE YggA)
KW548_02760	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KW548_02765	COG0640	Transcriptional regulator
KW548_02770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KW548_02815	COG2095	MarC family integral membrane protein
KW548_02825	COG0742	ribosomal rna small subunit methyltransferase
KW548_02830	COG0552	protein localization to endoplasmic reticulum
KW548_02840	COG2177	Part of the ABC transporter FtsEX involved in
KW548_02850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KW548_02855	COG0705	Rhomboid family
KW548_02860	COG1580	Controls the rotational direction of flagella during chemotaxis
KW548_02865	COG3161	chorismate lyase activity
KW548_02870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KW548_02875	COG2937	Belongs to the GPAT DAPAT family
KW548_02880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KW548_02885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KW548_02895	COG0534	Mate efflux family protein
KW548_02900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KW548_02920	COG4206	TonB-dependent receptor
KW548_02930	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KW548_03020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KW548_03030	COG0137	argininosuccinate synthase activity
KW548_03045	COG0251	oxidation-reduction process
KW548_03055	COG0678	peroxiredoxin activity
KW548_03055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KW548_03065	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
KW548_03100	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KW548_03110	COG0338	D12 class N6 adenine-specific DNA methyltransferase
KW548_03115	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KW548_03120	COG0546	phosphoglycolate phosphatase activity
KW548_03125	COG0180	Tryptophanyl-tRNA synthetase
KW548_03130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KW548_03135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KW548_03140	COG2205	protein histidine kinase activity
KW548_03145	COG0745	RESPONSE REGULATOR receiver
KW548_03150	COG3678	ATP-independent chaperone mediated protein folding
KW548_03155	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KW548_03170	COG1509	lysine 2,3-aminomutase activity
KW548_03175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KW548_03180	COG1575	Belongs to the MenA family. Type 1 subfamily
KW548_03185	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KW548_03190	COG0534	Mate efflux family protein
KW548_03195	COG0149	triose-phosphate isomerase activity
KW548_03215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KW548_03225	COG2095	MarC family integral membrane protein
KW548_03235	COG4232	protein-disulfide reductase activity
KW548_03240	COG1438	arginine binding
KW548_03245	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KW548_03250	COG0540	Belongs to the ATCase OTCase family
KW548_03255	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KW548_03275	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
KW548_03280	COG1027	Aspartate ammonia-lyase
KW548_03330	COG3501	Rhs element vgr protein
KW548_03350	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KW548_03370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KW548_03380	COG1012	belongs to the aldehyde dehydrogenase family
KW548_03390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KW548_03395	COG3954	Phosphoribulokinase
KW548_03405	COG0429	hydrolase of the alpha beta-hydrolase fold
KW548_03415	COG0488	(ABC) transporter
KW548_03420	COG2249	NAD(P)H dehydrogenase (quinone) activity
KW548_03435	COG1047	Peptidyl-prolyl cis-trans
KW548_03445	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KW548_03450	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
KW548_03455	COG0557	exoribonuclease II activity
KW548_03460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KW548_03465	COG0051	transcription antitermination factor activity, RNA binding
KW548_03470	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KW548_03475	COG0088	Forms part of the polypeptide exit tunnel
KW548_03490	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KW548_03495	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KW548_03500	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KW548_03515	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KW548_03530	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KW548_03540	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KW548_03545	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KW548_03560	COG1841	ribosomal large subunit assembly
KW548_03565	COG0200	Binds to the 23S rRNA
KW548_03570	COG0201	protein transport
KW548_03580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KW548_03585	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KW548_03595	COG0202	RNA polymerase activity
KW548_03600	COG0203	ribosomal protein L17
KW548_03605	COG0545	Peptidyl-prolyl cis-trans isomerase
KW548_03620	COG2153	protein acetylation
KW548_03630	COG0737	Belongs to the 5'-nucleotidase family
KW548_03635	COG1648	precorrin-2 dehydrogenase activity
KW548_03635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KW548_03640	COG0175	sulfate reduction
KW548_03650	COG3273	potassium ion transport
KW548_03650	COG0471	metal ion transport
KW548_03665	COG0735	belongs to the Fur family
KW548_03670	COG5002	protein histidine kinase activity
KW548_03670	COG2205	protein histidine kinase activity
KW548_03670	COG0784	Response regulator, receiver
KW548_03675	COG3437	response regulator, receiver
KW548_03705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KW548_03710	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KW548_03715	COG0175	sulfate reduction
KW548_03780	COG2239	Acts as a magnesium transporter
KW548_03785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW548_03790	COG1660	Displays ATPase and GTPase activities
KW548_03795	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW548_03800	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KW548_03810	COG1137	ATPase activity
KW548_03815	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KW548_03825	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KW548_03830	COG0517	IMP dehydrogenase activity
KW548_03830	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KW548_03840	COG1127	ABC transporter
KW548_03845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KW548_03850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KW548_03855	COG2854	intermembrane phospholipid transfer
KW548_03865	COG5007	Belongs to the BolA IbaG family
KW548_03875	COG0204	Acyl-transferase
KW548_03930	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KW548_03940	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KW548_03945	COG2066	Belongs to the glutaminase family
KW548_03955	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KW548_03975	COG0762	integral membrane protein
KW548_03980	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KW548_03985	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KW548_04000	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KW548_04005	COG1678	Uncharacterized ACR, COG1678
KW548_04010	COG0189	ligase activity
KW548_04015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KW548_04035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KW548_04040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KW548_04045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KW548_04055	COG0191	fructose-bisphosphate aldolase activity
KW548_04060	COG0668	transmembrane transport
KW548_04075	COG0583	DNA-binding transcription factor activity
KW548_04090	COG0469	pyruvate kinase activity
KW548_04095	COG1349	DNA-binding transcription factor activity
KW548_04100	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KW548_04105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KW548_04110	COG3722	fumarate hydratase activity
KW548_04115	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KW548_04125	COG0142	geranyltranstransferase activity
KW548_04130	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KW548_04145	COG2966	Psort location CytoplasmicMembrane, score
KW548_04150	COG3610	response to peptide
KW548_04155	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KW548_04170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KW548_04180	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KW548_04185	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KW548_04190	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KW548_04210	COG0358	DNA primase activity
KW548_04215	COG1610	YqeY-like protein
KW548_04220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KW548_04225	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KW548_04235	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KW548_04240	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KW548_04245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KW548_04250	COG1968	undecaprenyl-diphosphatase activity
KW548_04255	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KW548_04260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KW548_04265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KW548_04275	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KW548_04290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KW548_04295	COG4536	flavin adenine dinucleotide binding
KW548_04305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KW548_04310	COG0228	four-way junction DNA binding
KW548_04330	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KW548_04335	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KW548_04340	COG0237	dephospho-CoA kinase activity
KW548_04350	COG1459	type II secretion system
KW548_04360	COG4969	Belongs to the N-Me-Phe pilin family
KW548_04365	COG0157	Belongs to the NadC ModD family
KW548_04385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KW548_04390	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KW548_04395	COG2186	Transcriptional regulator
KW548_04400	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KW548_04405	COG0508	dehydrogenase complex catalyzes the overall conversion of
KW548_04410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KW548_04425	COG0288	reversible hydration of carbon dioxide
KW548_04430	COG0659	secondary active sulfate transmembrane transporter activity
KW548_04440	COG0842	Transport permease protein
KW548_04450	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KW548_04455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KW548_04470	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KW548_04480	COG1643	Atp-dependent helicase
KW548_04495	COG1049	propionate catabolic process, 2-methylcitrate cycle
KW548_04515	COG1840	ABC-type Fe3 transport system, periplasmic component
KW548_04525	COG3842	ATPase activity
KW548_04530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KW548_04555	COG4608	Belongs to the ABC transporter superfamily
KW548_04560	COG0444	Belongs to the ABC transporter superfamily
KW548_04575	COG0747	negative chemotaxis
KW548_04580	COG0784	Response regulator, receiver
KW548_04580	COG2205	protein histidine kinase activity
KW548_04590	COG0628	permease
KW548_04600	COG0316	Belongs to the HesB IscA family
KW548_04615	COG0739	heme binding
KW548_04620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KW548_04630	COG2027	D-alanyl-D-alanine carboxypeptidase
KW548_04635	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
KW548_04640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KW548_04645	COG1534	Rna-binding protein
KW548_04650	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KW548_04660	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KW548_04665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KW548_04675	COG0456	acetyltransferase
KW548_04690	COG0513	Belongs to the DEAD box helicase family
KW548_04695	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KW548_04710	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KW548_04715	COG0826	peptidase U32
KW548_04720	COG0826	peptidase U32
KW548_04730	COG3154	lipid carrier protein
KW548_04735	COG3153	acetyltransferase
KW548_04740	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KW548_04755	COG0779	Required for maturation of 30S ribosomal subunits
KW548_04760	COG0195	Participates in both transcription termination and antitermination
KW548_04765	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KW548_04785	COG0493	'glutamate synthase
KW548_04790	COG0069	glutamate synthase activity
KW548_04790	COG0070	glutamate synthase
KW548_04790	COG0067	glutamate synthase
KW548_04800	COG0067	glutamate synthase
KW548_04800	COG0070	glutamate synthase
KW548_04800	COG0069	glutamate synthase activity
KW548_04805	COG1242	4 iron, 4 sulfur cluster binding
KW548_04810	COG2203	Gaf domain
KW548_04810	COG3706	GGDEF domain
KW548_04810	COG4251	negative regulation of phosphorylation
KW548_04810	COG5001	Diguanylate cyclase
KW548_04815	COG0784	Response regulator, receiver
KW548_04815	COG5002	protein histidine kinase activity
KW548_04815	COG2198	Histidine kinase
KW548_04825	COG1538	Outer membrane efflux protein
KW548_04830	COG0494	nUDIX hydrolase
KW548_04835	COG3151	Protein conserved in bacteria
KW548_04845	COG3150	esterase
KW548_04860	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KW548_04870	COG3105	Protein conserved in bacteria
KW548_04890	COG0723	plastoquinol--plastocyanin reductase activity
KW548_04895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KW548_04900	COG2857	Cytochrome c1
KW548_04905	COG0625	glutathione transferase activity
KW548_04910	COG2969	positive regulation of protein catabolic process
KW548_04915	COG2823	Periplasmic or secreted lipoprotein
KW548_04925	COG0792	nuclease activity
KW548_04930	COG3107	peptidoglycan biosynthetic process
KW548_04935	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KW548_04955	COG3116	cell division
KW548_04960	COG0768	penicillin binding
KW548_04965	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KW548_04970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KW548_04985	COG0772	Belongs to the SEDS family
KW548_04990	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KW548_04995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KW548_05000	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KW548_05005	COG0849	cell division
KW548_05010	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KW548_05015	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KW548_05025	COG0494	nUDIX hydrolase
KW548_05035	COG0505	Belongs to the CarA family
KW548_05045	COG0730	response to heat
KW548_05050	COG0583	DNA-binding transcription factor activity
KW548_05055	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
KW548_05060	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KW548_05065	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KW548_05080	COG1115	amino acid carrier protein
KW548_05085	COG3022	response to hydroperoxide
KW548_05095	COG0084	hydrolase, TatD family'
KW548_05100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KW548_05105	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KW548_05110	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
KW548_05115	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KW548_05120	COG0813	purine-nucleoside phosphorylase activity
KW548_05130	COG0560	Phosphoserine phosphatase
KW548_05140	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KW548_05150	COG0693	protein deglycase activity
KW548_05155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KW548_05170	COG1595	DNA-templated transcription, initiation
KW548_05180	COG2211	Major facilitator Superfamily
KW548_05195	COG2813	Specifically methylates the guanine in position
KW548_05200	COG0271	Belongs to the BolA IbaG family
KW548_05210	COG1805	sodium ion transport
KW548_05225	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KW548_05230	COG2871	sodium ion transport
KW548_05235	COG1477	protein flavinylation
KW548_05250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KW548_05260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KW548_05275	COG0733	neurotransmitter:sodium symporter activity
KW548_05285	COG0189	ligase activity
KW548_05290	COG4067	protein conserved in archaea
KW548_05290	COG0189	ligase activity
KW548_05295	COG2195	Cleaves the N-terminal amino acid of tripeptides
KW548_05305	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KW548_05310	COG1073	alpha beta
KW548_05320	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KW548_05325	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KW548_05330	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KW548_05335	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KW548_05335	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KW548_05355	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KW548_05360	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KW548_05365	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KW548_05380	COG0024	Methionine aminopeptidase
KW548_05385	COG0052	Belongs to the universal ribosomal protein uS2 family
KW548_05390	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KW548_05395	COG0528	UMP kinase activity
KW548_05400	COG0233	cytoplasmic translational termination
KW548_05405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KW548_05410	COG0575	Belongs to the CDS family
KW548_05420	COG0750	zinc metalloprotease
KW548_05425	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KW548_05430	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
KW548_05435	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KW548_05440	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KW548_05455	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KW548_05460	COG0587	DNA-directed DNA polymerase activity
KW548_05480	COG0347	Belongs to the P(II) protein family
KW548_05485	COG3021	interspecies interaction between organisms
KW548_05495	COG1388	LysM domain
KW548_05495	COG0741	lytic transglycosylase activity
KW548_05500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KW548_05505	COG2226	methyltransferase
KW548_05510	COG0328	RNA-DNA hybrid ribonuclease activity
KW548_05525	COG1960	acyl-CoA dehydrogenase activity
KW548_05530	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KW548_05535	COG0121	glutamine amidotransferase
KW548_05545	COG1720	tRNA m6t6A37 methyltransferase activity
KW548_05550	COG0254	rRNA binding
KW548_05560	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KW548_05565	COG1464	Belongs to the NlpA lipoprotein family
KW548_05570	COG2011	ABC-type metal ion transport system permease component
KW548_05575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KW548_05580	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KW548_05590	COG1609	Transcriptional regulator
KW548_05595	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KW548_05595	COG1263	PTS System
KW548_05600	COG0366	Alpha amylase catalytic
KW548_05630	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KW548_05640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KW548_05655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KW548_05665	COG2921	Belongs to the UPF0250 family
KW548_05670	COG1686	Belongs to the peptidase S11 family
KW548_05675	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KW548_05680	COG0772	Belongs to the SEDS family
KW548_05690	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KW548_05695	COG0799	negative regulation of ribosome biogenesis
KW548_05705	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
KW548_05710	COG0495	leucyl-tRNA aminoacylation
KW548_05715	COG2888	peptidyl-tyrosine sulfation
KW548_05720	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KW548_05725	COG4535	Mg2 and Co2 transporter CorC
KW548_05730	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KW548_05735	COG1702	phosphate starvation-inducible protein PhoH
KW548_05745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KW548_05750	COG2190	(PTS) system
KW548_05755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KW548_05760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW548_05770	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
KW548_05780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KW548_05800	COG0330	HflC and HflK could
KW548_05805	COG3118	belongs to the thioredoxin family
KW548_05810	COG0300	oxidoreductase activity
KW548_05815	COG1090	epimerase
KW548_05840	COG0622	Phosphoesterase
KW548_05860	COG3710	Transcriptional regulator
KW548_05865	COG0326	Molecular chaperone. Has ATPase activity
KW548_05875	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KW548_05895	COG2217	Heavy metal translocating P-type atpase
KW548_05895	COG2608	mercury ion transmembrane transporter activity
KW548_05910	COG3047	cAMP biosynthetic process
KW548_05910	COG2885	chlorophyll binding
KW548_05920	COG4106	trans-aconitate 2-methyltransferase activity
KW548_05965	COG2747	anti-sigma28 factor FlgM
KW548_05975	COG0835	chemotaxis
KW548_05975	COG0784	Response regulator, receiver
KW548_05980	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KW548_05985	COG1815	bacterial-type flagellum-dependent cell motility
KW548_06005	COG4787	bacterial-type flagellum-dependent cell motility
KW548_06015	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
KW548_06020	COG1706	bacterial-type flagellum-dependent cell motility
KW548_06025	COG3951	Flagellar rod assembly protein muramidase FlgJ
KW548_06025	COG1705	Flagellar rod assembly protein muramidase FlgJ
KW548_06035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KW548_06055	COG4974	Belongs to the 'phage' integrase family
KW548_06130	COG4695	Portal protein
KW548_06365	COG0012	GTP binding
KW548_06375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KW548_06380	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KW548_06395	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KW548_06400	COG2890	protein-(glutamine-N5) methyltransferase activity
KW548_06410	COG2912	Transglutaminase-like superfamily
KW548_06415	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KW548_06425	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KW548_06450	COG1393	Belongs to the ArsC family
KW548_06455	COG4783	chaperone-mediated protein folding
KW548_06475	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KW548_06480	COG2716	regulation of RNA biosynthetic process
KW548_06490	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KW548_06495	COG2056	Na+-H+ antiporter family
KW548_06515	COG0346	lactoylglutathione lyase activity
KW548_06520	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KW548_06525	COG4660	Part of a membrane complex involved in electron transport
KW548_06530	COG4659	FMN binding
KW548_06540	COG4656	Part of a membrane complex involved in electron transport
KW548_06550	COG4657	Part of a membrane complex involved in electron transport
KW548_06555	COG1388	LysM domain
KW548_06555	COG0741	lytic transglycosylase activity
KW548_06575	COG1815	bacterial-type flagellum-dependent cell motility
KW548_06590	COG1749	Flagellar hook protein flgE
KW548_06595	COG4787	bacterial-type flagellum-dependent cell motility
KW548_06600	COG4786	Flagellar basal body rod
KW548_06610	COG1706	bacterial-type flagellum-dependent cell motility
KW548_06620	COG1256	bacterial-type flagellum assembly
KW548_06620	COG4786	Flagellar basal body rod
KW548_06640	COG1360	Flagellar Motor Protein
KW548_06645	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KW548_06650	COG1191	sigma factor activity
KW548_06655	COG1580	Controls the rotational direction of flagella during chemotaxis
KW548_06670	COG1516	flagellar protein fliS
KW548_06675	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KW548_06750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KW548_06765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KW548_06775	COG1987	bacterial-type flagellum assembly
KW548_06840	COG0739	heme binding
KW548_06850	COG1132	(ABC) transporter
KW548_06855	COG1132	(ABC) transporter
KW548_06860	COG1021	2,3-dihydroxybenzoate-AMP ligase
KW548_06885	COG3433	isochorismatase activity
KW548_06885	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KW548_06885	COG2226	methyltransferase
KW548_06890	COG2814	Major facilitator Superfamily
KW548_06895	COG4771	TonB-dependent receptor
KW548_06900	COG1917	Cupin 2, conserved barrel domain protein
KW548_06900	COG4977	sequence-specific DNA binding
KW548_06915	COG0556	nucleotide-excision repair
KW548_06925	COG2198	Histidine kinase
KW548_06930	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KW548_06935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KW548_06940	COG0521	Mo-molybdopterin cofactor biosynthetic process
KW548_06950	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KW548_06965	COG0517	IMP dehydrogenase activity
KW548_06965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KW548_06965	COG0617	tRNA 3'-terminal CCA addition
KW548_07000	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KW548_07000	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KW548_07005	COG0489	protein tyrosine kinase activity
KW548_07010	COG0572	uridine kinase
KW548_07015	COG2982	Protein involved in outer membrane biogenesis
KW548_07020	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
KW548_07030	COG0302	gtp cyclohydrolase
KW548_07035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KW548_07040	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KW548_07040	COG0302	gtp cyclohydrolase
KW548_07045	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KW548_07065	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KW548_07070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KW548_07080	COG1881	PFAM PEBP family protein
KW548_07090	COG0123	including yeast histone deacetylase and acetoin utilization protein
KW548_07110	COG0583	DNA-binding transcription factor activity
KW548_07115	COG0583	DNA-binding transcription factor activity
KW548_07170	COG3083	sulfuric ester hydrolase activity
KW548_07175	COG3082	Protein of unknown function (DUF1414)
KW548_07180	COG3081	Nucleoid-associated protein
KW548_07200	COG1757	Na H antiporter
KW548_07205	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KW548_07210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KW548_07215	COG2095	MarC family integral membrane protein
KW548_07220	COG1012	belongs to the aldehyde dehydrogenase family
KW548_07220	COG1454	alcohol dehydrogenase
KW548_07225	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KW548_07230	COG2894	cell division
KW548_07235	COG0850	regulation of cytokinetic process
KW548_07245	COG2951	lytic endotransglycosylase activity
KW548_07250	COG0583	DNA-binding transcription factor activity
KW548_07255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KW548_07270	COG2983	Belongs to the UPF0260 family
KW548_07310	COG1785	Belongs to the alkaline phosphatase family
KW548_07325	COG2226	methyltransferase
KW548_07335	COG0676	glucose-6-phosphate 1-epimerase activity
KW548_07345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KW548_07355	COG3139	Protein of unknown function (DUF1315)
KW548_07360	COG3012	SEC-C Motif Domain Protein
KW548_07365	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
KW548_07375	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KW548_07380	COG0215	cysteine-tRNA ligase activity
KW548_07385	COG1435	thymidine kinase activity
KW548_07390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KW548_07400	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KW548_07420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KW548_07425	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KW548_07430	COG0297	glycogen (starch) synthase activity
KW548_07465	COG0745	RESPONSE REGULATOR receiver
KW548_07475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KW548_07485	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
KW548_07505	COG4067	protein conserved in archaea
KW548_07505	COG0189	ligase activity
KW548_07510	COG0500	methyltransferase
KW548_07540	COG1278	Cold shock
KW548_07545	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KW548_07550	COG0542	response to heat
KW548_07575	COG2116	formate transmembrane transporter activity
KW548_07585	COG0390	transport system, permease component
KW548_07590	COG4459	periplasmic nitrate reductase
KW548_07595	COG3005	denitrification pathway
KW548_07600	COG0243	molybdopterin cofactor binding
KW548_07615	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KW548_07620	COG0632	four-way junction helicase activity
KW548_07630	COG1271	oxidase subunit
KW548_07635	COG1294	oxidase, subunit
KW548_07640	COG4890	Cyd operon protein YbgT
KW548_07650	COG0824	Thioesterase
KW548_07655	COG0811	peptide transport
KW548_07670	COG0823	Involved in the tonB-independent uptake of proteins
KW548_07675	COG2885	chlorophyll binding
KW548_07680	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
KW548_07685	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KW548_07720	COG5002	protein histidine kinase activity
KW548_07720	COG0784	Response regulator, receiver
KW548_07755	COG1902	pentaerythritol trinitrate reductase activity
KW548_07785	COG0693	protein deglycase activity
KW548_07800	COG0515	serine threonine protein kinase
KW548_07800	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KW548_07805	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KW548_07830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KW548_07830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KW548_07835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KW548_07835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KW548_07870	COG4932	domain protein
KW548_07870	COG5492	domain, Protein
KW548_07890	COG5492	domain, Protein
KW548_07890	COG4932	domain protein
KW548_07895	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KW548_07970	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KW548_07975	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KW548_07980	COG0732	type I restriction modification DNA specificity domain
KW548_08010	COG3710	Transcriptional regulator
KW548_08085	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KW548_08090	COG1482	cell wall glycoprotein biosynthetic process
KW548_08110	COG5002	protein histidine kinase activity
KW548_08110	COG3850	Histidine kinase
KW548_08120	COG0463	Glycosyl transferase, family 2
KW548_08125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KW548_08145	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KW548_08175	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KW548_08190	COG0708	Exodeoxyribonuclease III
KW548_08195	COG0840	transmembrane signaling receptor activity
KW548_08200	COG2850	peptidyl-arginine hydroxylation
KW548_08215	COG0730	response to heat
KW548_08220	COG1199	ATP-dependent helicase activity
KW548_08235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KW548_08245	COG0156	8-amino-7-oxononanoate synthase activity
KW548_08250	COG2226	methyltransferase
KW548_08250	COG1073	alpha beta
KW548_08255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KW548_08275	COG4221	oxidoreductase activity
KW548_08300	COG2268	Band 7 protein
KW548_08310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KW548_08330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KW548_08335	COG2916	Histone family protein nucleoid-structuring protein H-NS
KW548_08340	COG1757	Na H antiporter
KW548_08350	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KW548_08360	COG0131	Imidazoleglycerol-phosphate dehydratase
KW548_08360	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KW548_08365	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KW548_08380	COG0140	phosphoribosyl-ATP diphosphatase activity
KW548_08380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KW548_08385	COG0840	transmembrane signaling receptor activity
KW548_08390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KW548_08400	COG1227	inorganic diphosphatase activity
KW548_08415	COG4172	Belongs to the ABC transporter superfamily
KW548_08440	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
KW548_08445	COG1842	Phage shock protein A
KW548_08455	COG1983	PspC domain protein
KW548_08475	COG2818	Glycosylase
KW548_08480	COG5380	lipid catabolic process
KW548_08485	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
KW548_08490	COG0626	cystathionine gamma-synthase activity
KW548_08505	COG0564	pseudouridine synthase activity
KW548_08510	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KW548_08520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KW548_08525	COG4136	ATPase activity
KW548_08530	COG4135	transport system, permease component
KW548_08545	COG3313	Fe-S protein
KW548_08560	COG2350	Protein conserved in bacteria
KW548_08585	COG0776	regulation of translation
KW548_08595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KW548_08635	COG2197	response regulator
KW548_08670	COG1902	pentaerythritol trinitrate reductase activity
KW548_08680	COG2133	pyrroloquinoline quinone binding
KW548_08710	COG0072	phenylalanine-tRNA ligase activity
KW548_08710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KW548_08740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KW548_08740	COG1263	PTS System
KW548_08755	COG1621	beta-fructofuranosidase activity
KW548_08760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KW548_08775	COG0534	Mate efflux family protein
KW548_08780	COG0583	DNA-binding transcription factor activity
KW548_08785	COG0277	FAD linked oxidase domain protein
KW548_08810	COG0488	(ABC) transporter
KW548_08820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW548_08835	COG0642	Histidine kinase
KW548_08845	COG2801	Transposase and inactivated derivatives
KW548_08860	COG0352	thiamine-phosphate diphosphorylase activity
KW548_08865	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KW548_08870	COG1280	lysine exporter protein (LysE YggA)
KW548_08875	COG1115	amino acid carrier protein
KW548_08935	COG4580	involved in the transport of maltose and maltodextrins
KW548_08940	COG0237	dephospho-CoA kinase activity
KW548_08950	COG0519	Catalyzes the synthesis of GMP from XMP
KW548_08955	COG0242	peptide deformylase activity
KW548_08985	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KW548_08995	COG0583	DNA-binding transcription factor activity
KW548_09005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KW548_09010	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KW548_09120	COG4771	TonB-dependent receptor
KW548_09130	COG5492	domain, Protein
KW548_09130	COG4932	domain protein
KW548_09135	COG4932	domain protein
KW548_09135	COG5492	domain, Protein
KW548_09245	COG0463	Glycosyl transferase, family 2
KW548_09265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW548_09275	COG0745	RESPONSE REGULATOR receiver
KW548_09310	COG1061	Type III restriction enzyme res subunit
KW548_09320	COG2814	Major facilitator Superfamily
KW548_09335	COG0534	Mate efflux family protein
KW548_09340	COG1136	(ABC) transporter
KW548_09345	COG0577	efflux transmembrane transporter activity
KW548_09385	COG0019	diaminopimelate decarboxylase activity
KW548_09410	COG0633	Ferredoxin
KW548_09415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KW548_09420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KW548_09425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KW548_09435	COG0840	transmembrane signaling receptor activity
KW548_09445	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KW548_09485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KW548_09490	COG0745	RESPONSE REGULATOR receiver
KW548_09505	COG0811	peptide transport
KW548_09510	COG0811	peptide transport
KW548_09515	COG0848	biopolymer transport protein
KW548_09530	COG3290	protein histidine kinase activity
KW548_09535	COG4565	transcriptional regulatory protein
KW548_09555	COG2199	diguanylate cyclase activity
KW548_09595	COG3969	phosphoadenosine phosphosulfate
KW548_09600	COG1475	DNA binding
KW548_09610	COG0745	RESPONSE REGULATOR receiver
KW548_09620	COG3713	MltA-interacting MipA family protein
KW548_09640	COG0583	DNA-binding transcription factor activity
KW548_09655	COG3835	regulator
KW548_09660	COG1929	Belongs to the glycerate kinase type-1 family
KW548_09670	COG1120	ATPase activity
KW548_09675	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KW548_09685	COG4615	Cyclic peptide transporter
KW548_09705	COG4774	siderophore transport
KW548_09745	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KW548_09755	COG0297	glycogen (starch) synthase activity
KW548_09800	COG2204	response regulator
KW548_09845	COG0534	Mate efflux family protein
KW548_09850	COG0307	riboflavin synthase, alpha
KW548_09870	COG0791	NLP P60 protein
KW548_09875	COG0840	transmembrane signaling receptor activity
KW548_09885	COG3148	PFAM DTW domain containing protein
KW548_09905	COG0303	'Molybdopterin
KW548_09925	COG1595	DNA-templated transcription, initiation
KW548_09935	COG0488	(ABC) transporter
KW548_09970	COG0069	glutamate synthase activity
KW548_09995	COG0583	DNA-binding transcription factor activity
KW548_10005	COG0583	DNA-binding transcription factor activity
KW548_10080	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KW548_10085	COG2199	diguanylate cyclase activity
KW548_10095	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KW548_10100	COG1177	transmembrane transport
KW548_10110	COG3842	ATPase activity
KW548_10135	COG0589	response to stress
KW548_10140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KW548_10155	COG2217	Heavy metal translocating P-type atpase
KW548_10165	COG2010	Cytochrome c
KW548_10210	COG2197	response regulator
KW548_10425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KW548_10645	COG3120	sequence-specific DNA binding
KW548_10650	COG1067	ATP-dependent peptidase activity
KW548_10655	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KW548_10670	COG0488	(ABC) transporter
KW548_10690	COG0167	dihydroorotate dehydrogenase activity
KW548_10705	COG0308	aminopeptidase N
KW548_10720	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
KW548_10725	COG1956	GAF domain-containing protein
KW548_10730	COG1132	(ABC) transporter
KW548_10735	COG2995	paraquat-inducible protein a
KW548_10740	COG3008	intermembrane lipid transfer
KW548_10745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KW548_10745	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KW548_10770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KW548_10785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW548_10790	COG4597	amino acid ABC transporter
KW548_10800	COG1126	abc transporter atp-binding protein
KW548_10805	COG0670	Belongs to the BI1 family
KW548_10810	COG2920	part of a sulfur-relay system
KW548_10850	COG0602	queuosine metabolic process
KW548_10855	COG0561	phosphatase activity
KW548_10875	COG2828	Protein conserved in bacteria
KW548_10890	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KW548_11005	COG0515	serine threonine protein kinase
KW548_11060	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KW548_11085	COG1451	nucleotide metabolic process
KW548_11095	COG0784	Response regulator, receiver
KW548_11095	COG5002	protein histidine kinase activity
KW548_11110	COG2814	Major facilitator Superfamily
KW548_11130	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
KW548_11155	COG0702	epimerase
KW548_11160	COG1823	symporter activity
KW548_11200	COG2925	Exonuclease
KW548_11205	COG1380	Effector of murein hydrolase LrgA
KW548_11210	COG1346	cytolysis
KW548_11215	COG0295	cytidine deaminase activity
KW548_11265	COG4326	sporulation control protein
KW548_11270	COG2188	Transcriptional regulator
KW548_11275	COG1228	amidohydrolase
KW548_11280	COG0010	Belongs to the arginase family
KW548_11290	COG2986	histidine ammonia-lyase
KW548_11320	COG2885	chlorophyll binding
KW548_11335	COG0625	glutathione transferase activity
KW548_11345	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KW548_11380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KW548_11385	COG0454	-acetyltransferase
KW548_11450	COG3040	lipid binding
KW548_11485	COG2824	Alkylphosphonate utilization operon protein PhnA
KW548_11495	COG4628	conserved protein (DUF2132)
KW548_11500	COG0583	DNA-binding transcription factor activity
KW548_11505	COG0625	glutathione transferase activity
KW548_11510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KW548_11515	COG0583	DNA-binding transcription factor activity
KW548_11525	COG0252	asparaginase activity
KW548_11535	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KW548_11545	COG2814	Major facilitator Superfamily
KW548_11550	COG2175	clavaminate synthase activity
KW548_11555	COG2807	transmembrane transport
KW548_11560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KW548_11575	COG1917	Cupin 2, conserved barrel domain protein
KW548_11610	COG3246	L-lysine catabolic process to acetate
KW548_11665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KW548_11670	COG1051	belongs to the nudix hydrolase family
KW548_11675	COG0346	lactoylglutathione lyase activity
KW548_11745	COG1028	Short-chain dehydrogenase reductase Sdr
KW548_11780	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KW548_11800	COG0724	RNA recognition motif
KW548_11825	COG1280	lysine exporter protein (LysE YggA)
KW548_11925	COG5492	domain, Protein
KW548_11925	COG4932	domain protein
KW548_11930	COG1280	lysine exporter protein (LysE YggA)
KW548_11980	COG0745	RESPONSE REGULATOR receiver
KW548_12040	COG2962	Rard protein
KW548_12070	COG0783	Belongs to the Dps family
KW548_12075	COG4667	esterase of the alpha-beta hydrolase superfamily
KW548_12105	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KW548_12120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KW548_12125	COG3108	Peptidase M15
KW548_12130	COG2989	Protein conserved in bacteria
KW548_12155	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KW548_12175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KW548_12240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KW548_12255	COG3106	COG3106 Predicted ATPase
KW548_12275	COG0784	Response regulator, receiver
KW548_12275	COG2205	protein histidine kinase activity
KW548_12285	COG0494	nUDIX hydrolase
KW548_12290	COG0814	amino acid
KW548_12295	COG1760	l-serine dehydratase
KW548_12300	COG0814	amino acid
KW548_12305	COG0720	synthase
KW548_12310	COG0840	transmembrane signaling receptor activity
KW548_12315	COG0017	Asparaginyl-tRNA synthetase
KW548_12335	COG3437	response regulator, receiver
KW548_12335	COG2770	Histidine kinase
KW548_12340	COG1448	Aminotransferase
KW548_12355	COG1643	Atp-dependent helicase
KW548_12360	COG0281	malic enzyme
KW548_12370	COG2949	membrane
KW548_12380	COG0612	Peptidase, M16
KW548_12410	COG0492	ferredoxin-NADP+ reductase activity
KW548_12415	COG4988	ABC transporter
KW548_12425	COG0384	phenazine biosynthesis protein PhzF
KW548_12430	COG1187	pseudouridine synthase activity
KW548_12445	COG0009	L-threonylcarbamoyladenylate synthase
KW548_12450	COG0613	PHP domain protein
KW548_12460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KW548_12465	COG0512	Glutamine amidotransferase of anthranilate synthase
KW548_12470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KW548_12475	COG0134	indole-3-glycerol-phosphate synthase activity
KW548_12475	COG0135	phosphoribosylanthranilate isomerase activity
KW548_12485	COG0159	tryptophan synthase activity
KW548_12490	COG1301	dicarboxylic acid transport
KW548_12500	COG1643	Atp-dependent helicase
KW548_12535	COG0443	Heat shock 70 kDa protein
KW548_12575	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KW548_12595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KW548_12605	COG1846	Transcriptional regulator
KW548_12610	COG1764	response to oxidative stress
KW548_12615	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KW548_12650	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KW548_12660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW548_12660	COG4191	Histidine kinase
KW548_12675	COG3070	regulator of competence-specific genes
KW548_12685	COG2431	L-lysine efflux transmembrane transporter activity
KW548_12695	COG0076	glutamate decarboxylase activity
KW548_12700	COG1737	Transcriptional regulator
KW548_12705	COG1012	belongs to the aldehyde dehydrogenase family
KW548_12705	COG1454	alcohol dehydrogenase
KW548_12715	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KW548_12725	COG4160	amino acid transport
KW548_12750	COG1882	Formate acetyltransferase
KW548_12775	COG3013	Belongs to the UPF0304 family
KW548_12780	COG3713	MltA-interacting MipA family protein
KW548_12785	COG2766	serine protein kinase
KW548_12795	COG2719	SpoVR family
KW548_12800	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KW548_12805	COG2835	tetraacyldisaccharide 4'-kinase activity
KW548_12810	COG1663	tetraacyldisaccharide 4'-kinase activity
KW548_12815	COG1132	(ABC) transporter
KW548_12830	COG4591	ABC-type transport system involved in lipoprotein release permease component
KW548_12835	COG1136	(ABC) transporter
KW548_12850	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KW548_12895	COG0537	adenosine 5'-monophosphoramidase activity
KW548_12910	COG2186	Transcriptional regulator
KW548_12915	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KW548_12925	COG1674	ftsk spoiiie
KW548_12935	COG0686	Belongs to the AlaDH PNT family
KW548_12940	COG3092	negative regulation of chromosome organization
KW548_12945	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KW548_12950	COG0857	belongs to the CobB CobQ family
KW548_12950	COG0280	phosphate acetyltransferase
KW548_12960	COG0435	Glutathione S-transferase
KW548_12970	COG0444	Belongs to the ABC transporter superfamily
KW548_12975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KW548_12980	COG0601	transmembrane transport
KW548_12995	COG2067	long-chain fatty acid transport protein
KW548_13025	COG1404	Belongs to the peptidase S8 family
KW548_13030	COG0840	transmembrane signaling receptor activity
KW548_13050	COG0577	efflux transmembrane transporter activity
KW548_13050	COG1136	(ABC) transporter
KW548_13070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW548_13075	COG3227	Zinc metalloprotease (Elastase)
KW548_13130	COG0189	ligase activity
KW548_13155	COG3409	Peptidoglycan-binding domain 1 protein
KW548_13155	COG3501	Rhs element vgr protein
KW548_13200	COG3409	Peptidoglycan-binding domain 1 protein
KW548_13200	COG3501	Rhs element vgr protein
KW548_13245	COG1278	Cold shock
KW548_13265	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KW548_13275	COG0732	type I restriction modification DNA specificity domain
KW548_13280	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KW548_13315	COG3706	GGDEF domain
KW548_13330	COG3126	Type III secretion system lipoprotein chaperone (YscW)
KW548_13335	COG1946	Acyl-CoA thioesterase
KW548_13375	COG2855	membrane
KW548_13385	COG0318	PFAM AMP-dependent synthetase and ligase
KW548_13400	COG0596	Alpha beta hydrolase
KW548_13405	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KW548_13410	COG1169	isochorismate synthase
KW548_13415	COG0436	Aminotransferase
KW548_13425	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
KW548_13550	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KW548_13555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KW548_13580	COG1028	Short-chain dehydrogenase reductase Sdr
KW548_13595	COG0587	DNA-directed DNA polymerase activity
KW548_13600	COG0835	chemotaxis
KW548_13600	COG0784	Response regulator, receiver
KW548_13605	COG1940	carbohydrate kinase activity
KW548_13630	COG0733	neurotransmitter:sodium symporter activity
KW548_13645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KW548_13645	COG1263	PTS System
KW548_13650	COG0084	hydrolase, TatD family'
KW548_13655	COG0470	DNA polymerase III
KW548_13660	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KW548_13665	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KW548_13670	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KW548_13695	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KW548_13705	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KW548_13710	COG1399	metal-binding, possibly nucleic acid-binding protein
KW548_13715	COG0424	maF-like protein
KW548_13720	COG0564	pseudouridine synthase activity
KW548_13725	COG1530	ribonuclease E activity
KW548_13730	COG0659	secondary active sulfate transmembrane transporter activity
KW548_13735	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KW548_13740	COG0318	PFAM AMP-dependent synthetase and ligase
KW548_13745	COG2267	carboxylic ester hydrolase activity
KW548_13760	COG1214	PFAM Peptidase M22, glycoprotease
KW548_13765	COG1199	ATP-dependent helicase activity
KW548_13775	COG0788	formyltetrahydrofolate deformylase activity
KW548_13780	COG0446	pyridine nucleotide-disulphide oxidoreductase
KW548_13780	COG1902	pentaerythritol trinitrate reductase activity
KW548_13785	COG0616	signal peptide processing
KW548_13790	COG0252	asparaginase activity
KW548_13805	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KW548_13815	COG0653	protein targeting
KW548_13820	COG0659	secondary active sulfate transmembrane transporter activity
KW548_13825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KW548_13875	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
KW548_13885	COG0539	negative regulation of cytoplasmic translation
KW548_13890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KW548_13895	COG1555	photosystem II stabilization
KW548_13900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KW548_13905	COG0776	regulation of translation
KW548_13910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KW548_13945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KW548_13950	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KW548_13955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KW548_13960	COG3842	ATPase activity
KW548_13970	COG1175	transmembrane transport
KW548_13975	COG1653	transport
KW548_14000	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KW548_14005	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KW548_14020	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KW548_14025	COG2832	Protein of unknown function (DUF454)
KW548_14030	COG0745	RESPONSE REGULATOR receiver
KW548_14035	COG0583	DNA-binding transcription factor activity
KW548_14040	COG0778	Nitroreductase
KW548_14050	COG0183	Belongs to the thiolase family
KW548_14065	COG2067	long-chain fatty acid transport protein
KW548_14070	COG2067	long-chain fatty acid transport protein
KW548_14075	COG2853	Lipoprotein
KW548_14085	COG3088	subunit of a heme lyase
KW548_14085	COG4235	cytochrome complex assembly
KW548_14090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KW548_14095	COG1138	Cytochrome C-type biogenesis protein
KW548_14105	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KW548_14110	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KW548_14115	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KW548_14120	COG4133	protoheme IX ABC transporter activity
KW548_14130	COG0835	chemotaxis
KW548_14140	COG1192	Involved in chromosome partitioning
KW548_14145	COG2201	protein-glutamate methylesterase activity
KW548_14150	COG0643	Histidine kinase
KW548_14150	COG0784	Response regulator, receiver
KW548_14150	COG2198	Histidine kinase
KW548_14155	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
KW548_14185	COG2062	phosphohistidine phosphatase, SixA
KW548_14190	COG1025	Belongs to the peptidase M16 family
KW548_14195	COG3102	Protein conserved in bacteria
KW548_14200	COG0018	arginyl-trna synthetase
KW548_14215	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KW548_14220	COG1918	ferrous iron import across plasma membrane
KW548_14230	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KW548_14240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KW548_14245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KW548_14250	COG1286	toxin biosynthetic process
KW548_14255	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
KW548_14260	COG0285	dihydrofolate synthase activity
KW548_14265	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KW548_14270	COG0101	tRNA pseudouridine synthase activity
KW548_14280	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KW548_14290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KW548_14325	COG2860	membrane
KW548_14335	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KW548_14340	COG2890	protein-(glutamine-N5) methyltransferase activity
KW548_14360	COG1987	bacterial-type flagellum assembly
KW548_14410	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KW548_14420	COG1677	Flagellar hook-basal body complex protein FliE
KW548_14440	COG1516	flagellar protein fliS
KW548_14450	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KW548_14460	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KW548_14475	COG2837	iron assimilation
KW548_14505	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KW548_14520	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
KW548_14530	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KW548_14530	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KW548_14545	COG1611	Belongs to the LOG family
KW548_14560	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
KW548_14575	COG0583	DNA-binding transcription factor activity
KW548_14580	COG0301	tRNA thio-modification
KW548_14580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KW548_14590	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
KW548_14595	COG1722	exodeoxyribonuclease VII activity
KW548_14600	COG0142	geranyltranstransferase activity
KW548_14610	COG0564	pseudouridine synthase activity
KW548_14615	COG3098	single-species biofilm formation
KW548_14650	COG0508	dehydrogenase complex catalyzes the overall conversion of
KW548_14660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KW548_14670	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KW548_14685	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KW548_14695	COG0033	Phosphoglucomutase
KW548_14700	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
KW548_14705	COG0596	Alpha beta hydrolase
KW548_14725	COG0735	belongs to the Fur family
KW548_14730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KW548_14735	COG1263	PTS System
KW548_14735	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
KW548_14735	COG2190	(PTS) system
KW548_14740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KW548_14745	COG1846	Transcriptional regulator
KW548_14745	COG1940	carbohydrate kinase activity
KW548_14755	COG0367	asparagine synthase
KW548_14760	COG3104	oligopeptide transport
KW548_14785	COG2840	Smr protein MutS2
KW548_14790	COG1187	pseudouridine synthase activity
KW548_14795	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KW548_14805	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KW548_14830	COG0047	phosphoribosylformylglycinamidine synthase activity
KW548_14830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KW548_14835	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KW548_14845	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
KW548_14875	COG0484	heat shock protein binding
KW548_14880	COG0443	Heat shock 70 kDa protein
KW548_14885	COG1301	dicarboxylic acid transport
KW548_14890	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KW548_14905	COG0497	DNA recombination
KW548_14910	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KW548_14915	COG2914	Belongs to the UPF0125 (RnfH) family
KW548_14950	COG0668	transmembrane transport
KW548_14965	COG0204	Acyl-transferase
KW548_14970	COG0835	chemotaxis
KW548_14970	COG0784	Response regulator, receiver
KW548_14975	COG2873	o-acetylhomoserine
KW548_14990	COG0583	DNA-binding transcription factor activity
KW548_14995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KW548_15000	COG1115	amino acid carrier protein
KW548_15020	COG0516	GMP reductase activity
KW548_15020	COG0517	IMP dehydrogenase activity
KW548_15035	COG3706	GGDEF domain
KW548_15045	COG1160	GTP binding
KW548_15050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KW548_15055	COG2976	Protein conserved in bacteria
KW548_15060	COG0124	histidyl-tRNA synthetase
KW548_15065	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KW548_15080	COG2166	iron-sulfur cluster assembly
KW548_15085	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KW548_15110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KW548_15115	COG1074	ATP-dependent DNA helicase activity
KW548_15140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW548_15145	COG1309	transcriptional regulator
KW548_15150	COG3141	response to X-ray
KW548_15165	COG0704	Plays a role in the regulation of phosphate uptake
KW548_15170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KW548_15175	COG0581	inorganic phosphate transmembrane transporter activity
KW548_15180	COG0573	inorganic phosphate transmembrane transporter activity
KW548_15185	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KW548_15190	COG0248	Ppx GppA phosphatase
KW548_15200	COG5002	protein histidine kinase activity
KW548_15205	COG0745	RESPONSE REGULATOR receiver
KW548_15215	COG0826	peptidase U32
KW548_15220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KW548_15225	COG1294	oxidase, subunit
KW548_15230	COG1271	oxidase subunit
KW548_15250	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KW548_15255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KW548_15260	COG1862	Preprotein translocase
KW548_15270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KW548_15275	COG0517	IMP dehydrogenase activity
KW548_15305	COG1358	cellular component organization or biogenesis
KW548_15325	COG0840	transmembrane signaling receptor activity
KW548_15340	COG0583	DNA-binding transcription factor activity
KW548_15345	COG0450	alkyl hydroperoxide reductase
KW548_15350	COG2171	N-acyltransferase activity
KW548_15360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KW548_15370	COG2207	Transcriptional regulator
KW548_15375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KW548_15375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KW548_15375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW548_15405	COG2169	Transcriptional regulator
KW548_15410	COG1022	Amp-dependent synthetase and ligase
KW548_15415	COG0583	DNA-binding transcription factor activity
KW548_15425	COG0583	DNA-binding transcription factor activity
KW548_15430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KW548_15440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KW548_15445	COG2975	iron-sulfur cluster assembly
KW548_15450	COG0633	Ferredoxin
KW548_15455	COG0443	Heat shock 70 kDa protein
KW548_15470	COG0822	iron-sulfur transferase activity
KW548_15480	COG1959	2 iron, 2 sulfur cluster binding
KW548_15490	COG0483	inositol monophosphate 1-phosphatase activity
KW548_15530	COG0542	response to heat
KW548_15535	COG1496	oxidoreductase activity
KW548_15540	COG0564	pseudouridine synthase activity
KW548_15545	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KW548_15555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KW548_15560	COG0077	Prephenate dehydratase
KW548_15560	COG1605	Chorismate mutase
KW548_15565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KW548_15575	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
KW548_15580	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
KW548_15585	COG0741	lytic transglycosylase activity
KW548_15590	COG0488	(ABC) transporter
KW548_15600	COG0739	heme binding
KW548_15605	COG0287	Prephenate dehydrogenase
KW548_15605	COG1605	Chorismate mutase
KW548_15610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KW548_15615	COG3275	phosphorelay sensor kinase activity
KW548_15620	COG3279	Response regulator of the LytR AlgR family
KW548_15625	COG1472	Belongs to the glycosyl hydrolase 3 family
KW548_15630	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KW548_15635	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KW548_15650	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KW548_15655	COG1047	Peptidyl-prolyl cis-trans
KW548_15670	COG0196	riboflavin kinase activity
KW548_15675	COG0728	peptidoglycan biosynthetic process
KW548_15680	COG0268	Binds directly to 16S ribosomal RNA
KW548_15685	COG0640	Transcriptional regulator
KW548_15690	COG0583	DNA-binding transcription factor activity
KW548_15695	COG1283	sodium-dependent phosphate transmembrane transporter activity
KW548_15705	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KW548_15720	COG0494	nUDIX hydrolase
KW548_15735	COG0667	Aldo Keto reductase
KW548_15745	COG2204	response regulator
KW548_15750	COG0534	Mate efflux family protein
KW548_15755	COG1846	Transcriptional regulator
KW548_15800	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KW548_15810	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KW548_15820	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KW548_15825	COG2860	membrane
KW548_15830	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KW548_15835	COG0083	homoserine kinase activity
KW548_15855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KW548_15865	COG0745	RESPONSE REGULATOR receiver
KW548_15870	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KW548_15870	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KW548_15875	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KW548_15885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KW548_15890	COG3025	triphosphatase activity
KW548_15895	COG1392	Phosphate transport regulator
KW548_15900	COG0306	phosphate transporter
KW548_15915	COG3267	Type II secretory pathway component ExeA
KW548_15915	COG3409	Peptidoglycan-binding domain 1 protein
KW548_15930	COG0148	phosphopyruvate hydratase activity
KW548_15940	COG3956	TIGRFAM MazG family protein
KW548_15950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KW548_15960	COG0736	holo-[acyl-carrier-protein] synthase activity
KW548_15970	COG1381	Involved in DNA repair and RecF pathway recombination
KW548_15975	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KW548_15980	COG0571	ribonuclease III activity
KW548_15995	COG3086	response to oxidative stress
KW548_16000	COG3026	antisigma factor binding
KW548_16005	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
KW548_16010	COG1595	DNA-templated transcription, initiation
KW548_16040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KW548_16045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KW548_16050	COG3079	Belongs to the UPF0149 family
KW548_16055	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KW548_16065	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KW548_16075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KW548_16080	COG2271	Major facilitator Superfamily
KW548_16085	COG0584	glycerophosphoryl diester phosphodiesterase
KW548_16090	COG0440	acetolactate synthase activity
KW548_16095	COG0028	Belongs to the TPP enzyme family
KW548_16100	COG1022	Amp-dependent synthetase and ligase
KW548_16105	COG0583	DNA-binding transcription factor activity
KW548_16125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KW548_16140	COG0066	3-isopropylmalate dehydratase activity
KW548_16210	COG1854	S-ribosylhomocysteine lyase activity
KW548_16220	COG2918	glutathione biosynthetic process
KW548_16225	COG0612	Peptidase, M16
KW548_16230	COG1238	metal cluster binding
KW548_16245	COG5016	pyruvate
KW548_16245	COG0511	ligase activity, forming carbon-carbon bonds
KW548_16250	COG3630	sodium ion export across plasma membrane
KW548_16295	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KW548_16300	COG0527	aspartate kinase activity
KW548_16310	COG2137	regulation of response to DNA damage stimulus
KW548_16315	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KW548_16320	COG1546	Belongs to the CinA family
KW548_16350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KW548_16355	COG0795	lipopolysaccharide-transporting ATPase activity
KW548_16360	COG0795	lipopolysaccharide-transporting ATPase activity
KW548_16370	COG2927	DNA polymerase III (CHI subunit)
KW548_16375	COG0525	valine-tRNA ligase activity
KW548_16385	COG4269	membrane
KW548_16395	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KW548_16400	COG0564	pseudouridine synthase activity
KW548_16415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KW548_16430	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
KW548_16435	COG0251	oxidation-reduction process
KW548_16445	COG0039	L-malate dehydrogenase activity
KW548_16450	COG1438	arginine binding
KW548_16455	COG2358	TRAP transporter, solute receptor (TAXI family
KW548_16465	COG0589	response to stress
KW548_16495	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KW548_16515	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KW548_16525	COG1077	Cell shape determining protein MreB Mrl
KW548_16605	COG0156	8-amino-7-oxononanoate synthase activity
KW548_16625	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KW548_16630	COG3118	belongs to the thioredoxin family
KW548_16675	COG2315	Protein conserved in bacteria
KW548_16705	COG3706	GGDEF domain
KW548_16725	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
KW548_16730	COG1028	Short-chain dehydrogenase reductase Sdr
KW548_16740	COG1024	Enoyl-CoA hydratase
KW548_16745	COG1024	Enoyl-CoA hydratase
KW548_16770	COG1960	acyl-CoA dehydrogenase activity
KW548_16775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KW548_16810	COG2259	Doxx family
KW548_16815	COG1741	Belongs to the pirin family
KW548_16830	COG1115	amino acid carrier protein
KW548_16850	COG5001	Diguanylate cyclase
KW548_16850	COG1716	ATPase activity
KW548_16870	COG1278	Cold shock
KW548_16885	COG2814	Major facilitator Superfamily
KW548_16900	COG5654	RES domain protein
KW548_16905	COG5642	Protein of unknown function (DUF2384)
KW548_17045	COG1683	Conserved Protein
KW548_17090	COG1917	Cupin 2, conserved barrel domain protein
KW548_17090	COG4977	sequence-specific DNA binding
KW548_17125	COG4115	mRNA cleavage
KW548_17130	COG2161	toxin-antitoxin pair type II binding
KW548_17135	COG1335	isochorismatase
KW548_17195	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KW548_17200	COG5001	Diguanylate cyclase
KW548_17200	COG3300	MHYT domain
KW548_17205	COG0789	Transcriptional regulator
KW548_17215	COG2176	DNA-directed DNA polymerase activity
KW548_17220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KW548_17225	COG1846	Transcriptional regulator
KW548_17230	COG3706	GGDEF domain
KW548_17255	COG2814	Major facilitator Superfamily
KW548_17260	COG2425	protein containing a von Willebrand factor type A (vWA) domain
KW548_17270	COG0494	nUDIX hydrolase
KW548_17275	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
KW548_17300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KW548_17305	COG0835	chemotaxis
KW548_17305	COG0784	Response regulator, receiver
KW548_17310	COG3706	GGDEF domain
KW548_17335	COG2866	Carboxypeptidase
KW548_17340	COG3104	oligopeptide transport
KW548_17360	COG3842	ATPase activity
KW548_17370	COG1840	ABC-type Fe3 transport system, periplasmic component
KW548_17380	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KW548_17400	COG1011	Hydrolase
KW548_17415	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KW548_17420	COG1454	alcohol dehydrogenase
KW548_17445	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KW548_17470	COG3186	Phenylalanine-4-hydroxylase
KW548_17475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KW548_17480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KW548_17500	COG0784	Response regulator, receiver
KW548_17500	COG2205	protein histidine kinase activity
KW548_17505	COG0784	Response regulator, receiver
KW548_17505	COG2205	protein histidine kinase activity
KW548_17535	COG2195	Cleaves the N-terminal amino acid of tripeptides
KW548_17545	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KW548_17565	COG1063	alcohol dehydrogenase
KW548_17570	COG0156	8-amino-7-oxononanoate synthase activity
KW548_17580	COG0346	lactoylglutathione lyase activity
KW548_17590	COG4452	Inner membrane protein CreD
KW548_17595	COG2205	protein histidine kinase activity
KW548_17600	COG0745	RESPONSE REGULATOR receiver
KW548_17610	COG0745	RESPONSE REGULATOR receiver
KW548_17615	COG2205	protein histidine kinase activity
KW548_17800	COG0714	Associated with various cellular activities
KW548_17820	COG2304	oxidoreductase activity
KW548_17840	COG0110	maltose O-acetyltransferase activity
KW548_17845	COG1765	OsmC-like protein
KW548_17850	COG0673	inositol 2-dehydrogenase activity
KW548_17870	COG0531	amino acid
KW548_17875	COG0121	glutamine amidotransferase
KW548_17890	COG1566	PFAM secretion protein HlyD family protein
KW548_17895	COG0402	S-adenosylhomocysteine deaminase activity
KW548_17905	COG5002	protein histidine kinase activity
KW548_17905	COG2205	protein histidine kinase activity
KW548_17905	COG0784	Response regulator, receiver
KW548_17965	COG3833	ABC-type maltose transport systems, permease component
KW548_17980	COG3842	ATPase activity
KW548_17985	COG0748	coenzyme F420 binding
KW548_17990	COG3721	Heme iron utilization protein
KW548_18000	COG0811	peptide transport
KW548_18005	COG0848	biopolymer transport protein
KW548_18015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KW548_18020	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KW548_18025	COG2814	Major facilitator Superfamily
KW548_18035	COG0739	heme binding
KW548_18055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KW548_18065	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
KW548_18070	COG0513	Belongs to the DEAD box helicase family
KW548_18080	COG4191	Histidine kinase
KW548_18080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW548_18085	COG0784	Response regulator, receiver
KW548_18085	COG3437	response regulator, receiver
KW548_18090	COG1609	Transcriptional regulator
KW548_18095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KW548_18100	COG1879	ABC-type sugar transport system periplasmic component
KW548_18105	COG1172	Belongs to the binding-protein-dependent transport system permease family
KW548_18110	COG1129	ABC transporter
KW548_18175	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KW548_18225	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KW548_18230	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KW548_18270	COG2207	Transcriptional regulator
KW548_18270	COG4753	response regulator
KW548_18325	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
KW548_18380	COG3123	guanosine phosphorylase activity
KW548_18385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KW548_18395	COG0668	transmembrane transport
KW548_18425	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KW548_18465	COG3118	belongs to the thioredoxin family
KW548_18470	COG4232	protein-disulfide reductase activity
KW548_18485	COG1280	lysine exporter protein (LysE YggA)
KW548_18515	COG0443	Heat shock 70 kDa protein
KW548_18520	COG0583	DNA-binding transcription factor activity
KW548_18535	COG1396	sequence-specific DNA binding
KW548_18540	COG2199	diguanylate cyclase activity
KW548_18540	COG2203	Gaf domain
KW548_18560	COG0642	Histidine kinase
KW548_18580	COG2130	NADP-dependent
KW548_18625	COG0534	Mate efflux family protein
KW548_18630	COG0444	Belongs to the ABC transporter superfamily
KW548_18635	COG4608	Belongs to the ABC transporter superfamily
KW548_18640	COG0747	negative chemotaxis
KW548_18680	COG3279	Response regulator of the LytR AlgR family
KW548_18685	COG3275	phosphorelay sensor kinase activity
KW548_18700	COG4591	ABC-type transport system involved in lipoprotein release permease component
KW548_18705	COG1136	(ABC) transporter
KW548_18745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KW548_18750	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KW548_18750	COG2207	Transcriptional regulator
KW548_18760	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KW548_18760	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KW548_18775	COG0697	spore germination
KW548_18795	COG0415	Belongs to the DNA photolyase family
KW548_18825	COG0840	transmembrane signaling receptor activity
KW548_18840	COG4580	involved in the transport of maltose and maltodextrins
KW548_18870	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KW548_18880	COG0438	transferase activity, transferring glycosyl groups
KW548_18910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KW548_18915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KW548_18920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KW548_18935	COG5001	Diguanylate cyclase
KW548_18935	COG2203	Gaf domain
KW548_18935	COG3706	GGDEF domain
KW548_18935	COG4251	negative regulation of phosphorylation
KW548_18940	COG4989	oxidoreductase activity
KW548_18950	COG0366	Alpha amylase catalytic
KW548_18960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KW548_18965	COG1126	abc transporter atp-binding protein
KW548_18970	COG0765	amino acid transport
KW548_18975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW548_18980	COG0765	amino acid transport
KW548_18985	COG0109	protoheme IX farnesyltransferase activity
KW548_18990	COG1612	heme a metabolic process
KW548_19015	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
KW548_19020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KW548_19025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KW548_19030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KW548_19055	COG3314	Sporulation integral membrane protein YlbJ
KW548_19060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KW548_19085	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KW548_19095	COG1741	Belongs to the pirin family
KW548_19145	COG1280	lysine exporter protein (LysE YggA)
KW548_19150	COG0583	DNA-binding transcription factor activity
KW548_19190	COG2988	succinylglutamate desuccinylase activity
KW548_19230	COG3568	Endonuclease Exonuclease Phosphatase
KW548_19240	COG3291	Pkd domain containing protein
KW548_19245	COG0513	Belongs to the DEAD box helicase family
KW548_19275	COG1376	ErfK ybiS ycfS ynhG family protein
KW548_19275	COG1388	LysM domain
KW548_19280	COG0415	Belongs to the DNA photolyase family
KW548_19285	COG0789	Transcriptional regulator
KW548_19290	COG3272	Protein of unknown function (DUF1722)
KW548_19295	COG0813	purine-nucleoside phosphorylase activity
KW548_19325	COG1566	PFAM secretion protein HlyD family protein
KW548_19340	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KW548_19345	COG3246	L-lysine catabolic process to acetate
KW548_19355	COG0583	DNA-binding transcription factor activity
KW548_19365	COG1132	(ABC) transporter
KW548_19370	COG4974	Belongs to the 'phage' integrase family
KW548_19420	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KW548_19490	COG1346	cytolysis
KW548_19495	COG4228	DNA circulation
KW548_19510	COG4381	Mu-like prophage protein gp46
KW548_19540	COG3772	lysozyme
KW548_19555	COG4695	Portal protein
KW548_19595	COG4386	tail sheath protein
KW548_19695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KW548_19700	COG0259	pyridoxamine-phosphate oxidase activity
KW548_19730	COG3033	Beta-eliminating lyase
KW548_19735	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KW548_19755	COG1999	signal sequence binding
KW548_19775	COG2135	peptidase activity
KW548_19860	COG1733	regulation of RNA biosynthetic process
KW548_19925	COG0561	phosphatase activity
KW548_19975	COG1619	proteins homologs of microcin C7 resistance protein MccF
KW548_19985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KW548_19990	COG1640	4-alpha-glucanotransferase
KW548_19995	COG0058	SHG alpha-glucan phosphorylase activity
KW548_20000	COG2909	trisaccharide binding
KW548_20010	COG0456	acetyltransferase
KW548_20055	COG1404	Belongs to the peptidase S8 family
KW548_20080	COG2186	Transcriptional regulator
KW548_20090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KW548_20100	COG0402	S-adenosylhomocysteine deaminase activity
KW548_20105	COG2226	methyltransferase
KW548_20110	COG5002	protein histidine kinase activity
KW548_20110	COG2205	protein histidine kinase activity
KW548_20110	COG0784	Response regulator, receiver
KW548_20135	COG4266	Belongs to the allantoicase family
KW548_20160	COG0596	Alpha beta hydrolase
KW548_20200	COG0109	protoheme IX farnesyltransferase activity
KW548_20205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KW548_20210	COG1845	cytochrome c oxidase, subunit III
KW548_20215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KW548_20230	COG0840	transmembrane signaling receptor activity
KW548_20290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KW548_20330	COG1846	Transcriptional regulator
KW548_20355	COG1051	belongs to the nudix hydrolase family
KW548_20360	COG0583	DNA-binding transcription factor activity
KW548_20380	COG1733	regulation of RNA biosynthetic process
KW548_20395	COG1028	Short-chain dehydrogenase reductase Sdr
KW548_20430	COG0444	Belongs to the ABC transporter superfamily
KW548_20435	COG4608	Belongs to the ABC transporter superfamily
KW548_20460	COG1444	tRNA N-acetyltransferase activity
KW548_20465	COG0840	transmembrane signaling receptor activity
KW548_20480	COG2198	Histidine kinase
KW548_20480	COG0643	Histidine kinase
KW548_20490	COG0835	chemotaxis
KW548_20495	COG0840	transmembrane signaling receptor activity
KW548_20500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KW548_20560	COG0589	response to stress
KW548_20570	COG2723	6-phospho-beta-galactosidase activity
KW548_20580	COG2084	Dehydrogenase
KW548_20610	COG0156	8-amino-7-oxononanoate synthase activity
KW548_20615	COG2814	Major facilitator Superfamily
KW548_20640	COG0588	phosphoglycerate mutase activity
KW548_20665	COG3409	Peptidoglycan-binding domain 1 protein
KW548_20665	COG3501	Rhs element vgr protein
KW548_20685	COG2223	nitrite transmembrane transporter activity
KW548_20695	COG1063	alcohol dehydrogenase
KW548_20700	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KW548_20705	COG3152	Membrane
KW548_20740	COG2994	toxin metabolic process
KW548_20765	COG0840	transmembrane signaling receptor activity
KW548_20780	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KW548_20805	COG0583	DNA-binding transcription factor activity
KW548_20830	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KW548_20845	COG2199	diguanylate cyclase activity
KW548_20875	COG0604	alcohol dehydrogenase
KW548_20885	COG3842	ATPase activity
KW548_20890	COG0395	ABC-type sugar transport system, permease component
KW548_20955	COG0471	metal ion transport
KW548_21015	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KW548_21030	COG3850	Histidine kinase
KW548_21030	COG5002	protein histidine kinase activity
KW548_21035	COG0745	RESPONSE REGULATOR receiver
KW548_21045	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KW548_21060	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KW548_21105	COG3708	Transcriptional regulator
KW548_21105	COG2207	Transcriptional regulator
KW548_21140	COG1301	dicarboxylic acid transport
KW548_21290	COG0584	glycerophosphoryl diester phosphodiesterase
KW548_21380	COG2072	flavoprotein involved in K transport
KW548_21385	COG2175	clavaminate synthase activity
KW548_21395	COG1671	Belongs to the UPF0178 family
KW548_21405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KW548_21455	COG4175	Glycine betaine
KW548_21455	COG3448	diguanylate cyclase activity
KW548_21460	COG4176	ABC-type proline glycine betaine transport system permease component
KW548_21510	COG4964	Belongs to the GSP D family
KW548_21520	COG2894	cell division
KW548_21575	COG1477	protein flavinylation
KW548_21595	COG4221	oxidoreductase activity
KW548_21610	COG0573	inorganic phosphate transmembrane transporter activity
KW548_21615	COG0581	inorganic phosphate transmembrane transporter activity
KW548_21620	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KW548_21635	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
KW548_21640	COG1162	GTPase activity
KW548_21655	COG0363	glucosamine-6-phosphate deaminase activity
KW548_21670	COG0454	-acetyltransferase
KW548_21675	COG0840	transmembrane signaling receptor activity
KW548_21695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KW548_21705	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KW548_21710	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KW548_21715	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KW548_21740	COG1846	Transcriptional regulator
KW548_21770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KW548_21780	COG3314	Sporulation integral membrane protein YlbJ
KW548_21790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KW548_21805	COG0625	glutathione transferase activity
KW548_21820	COG0415	Belongs to the DNA photolyase family
KW548_21825	COG3046	protein related to deoxyribodipyrimidine photolyase
KW548_21835	COG2329	Antibiotic biosynthesis monooxygenase
KW548_21840	COG3304	Inner membrane component domain
KW548_21850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW548_21855	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KW548_21865	COG1234	tRNA 3'-trailer cleavage
KW548_21885	COG3383	formate dehydrogenase (NAD+) activity
KW548_21890	COG0446	pyridine nucleotide-disulphide oxidoreductase
KW548_21895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KW548_21915	COG0739	heme binding
KW548_21920	COG3047	cAMP biosynthetic process
KW548_21945	COG5553	Cysteine dioxygenase type I
KW548_21995	COG4191	Histidine kinase
KW548_21995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KW548_22000	COG1320	monovalent cation:proton antiporter activity
KW548_22005	COG2212	antiporter activity
KW548_22010	COG1863	multisubunit Na H antiporter MnhE subunit
KW548_22015	COG0651	ATP synthesis coupled electron transport
KW548_22020	COG1006	Multisubunit Na H antiporter MnhC subunit
KW548_22025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KW548_22025	COG2111	Na H antiporter
KW548_22035	COG0589	response to stress
KW548_22135	COG1690	Belongs to the RtcB family
KW548_22140	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KW548_22160	COG3541	Predicted nucleotidyltransferase
KW548_22165	COG1690	Belongs to the RtcB family
KW548_22185	COG4650	regulator
KW548_22235	COG1280	lysine exporter protein (LysE YggA)
KW548_22240	COG0456	acetyltransferase
KW548_22285	COG2026	Addiction module toxin, RelE StbE family
KW548_22305	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KW548_22370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KW548_22380	COG0509	glycine decarboxylation via glycine cleavage system
KW548_22385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KW548_22395	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KW548_22435	COG0583	DNA-binding transcription factor activity
KW548_22440	COG2814	Major facilitator Superfamily
KW548_22455	COG0697	spore germination
KW548_22465	COG0534	Mate efflux family protein
KW548_22480	COG0546	phosphoglycolate phosphatase activity
KW548_22490	COG3604	Transcriptional regulator
KW548_22495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KW548_22495	COG1017	nitric oxide dioxygenase activity
KW548_22510	COG1278	Cold shock
KW548_22515	COG3036	rescue of stalled ribosome
KW548_22530	COG1686	Belongs to the peptidase S11 family
KW548_22540	COG3530	Putative quorum-sensing-regulated virulence factor
KW548_22555	COG4589	Belongs to the CDS family
KW548_22600	COG3501	Rhs element vgr protein
KW548_22605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KW548_22650	COG1271	oxidase subunit
KW548_22655	COG1805	sodium ion transport
KW548_22675	COG3300	MHYT domain
KW548_22675	COG5001	Diguanylate cyclase
KW548_22695	COG1309	transcriptional regulator
KW548_22710	COG0745	RESPONSE REGULATOR receiver
KW548_22715	COG5002	protein histidine kinase activity
KW548_22750	COG0842	Transport permease protein
KW548_22755	COG1131	(ABC) transporter
KW548_22790	COG1054	Belongs to the UPF0176 family
KW548_22795	COG0346	lactoylglutathione lyase activity
KW548_22800	COG0625	glutathione transferase activity
KW548_22805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KW548_22810	COG0366	Alpha amylase catalytic
KW548_22815	COG2084	Dehydrogenase
KW548_22830	COG2130	NADP-dependent
KW548_22835	COG1309	transcriptional regulator
KW548_22850	COG3097	Belongs to the UPF0267 family
KW548_22855	COG0513	Belongs to the DEAD box helicase family
KW548_22865	COG1228	amidohydrolase
KW548_22875	COG0110	maltose O-acetyltransferase activity
KW548_22885	COG1028	Short-chain dehydrogenase reductase Sdr
KW548_22890	COG0583	DNA-binding transcription factor activity
KW548_22895	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KW548_22950	COG0251	oxidation-reduction process
KW548_22965	COG2356	endonuclease I
KW548_22990	COG0564	pseudouridine synthase activity
KW548_23010	COG0583	DNA-binding transcription factor activity
KW548_23015	COG2814	Major facilitator Superfamily
KW548_23050	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KW548_23060	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KW548_23065	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KW548_23095	COG1012	belongs to the aldehyde dehydrogenase family
KW548_23100	COG3284	Transcriptional regulator
KW548_23110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KW548_23115	COG0363	glucosamine-6-phosphate deaminase activity
KW548_23120	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KW548_23125	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KW548_23135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KW548_23145	COG2271	Major facilitator Superfamily
KW548_23155	COG2197	response regulator
KW548_23175	COG0418	dihydroorotase activity
KW548_23180	COG3217	Mosc domain protein beta barrel domain protein
KW548_23180	COG0633	Ferredoxin
KW548_23180	COG0633	Ferredoxin
KW548_23180	COG3217	Mosc domain protein beta barrel domain protein
KW548_23210	COG2354	Protein conserved in bacteria
KW548_23220	COG0366	Alpha amylase catalytic
KW548_23265	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KW548_23265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KW548_23270	COG0516	GMP reductase activity
KW548_23275	COG4974	Belongs to the 'phage' integrase family
KW548_23325	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
KW548_23380	COG1012	belongs to the aldehyde dehydrogenase family
KW548_23400	COG4175	Glycine betaine
KW548_23400	COG3448	diguanylate cyclase activity
KW548_23425	COG0583	DNA-binding transcription factor activity
KW548_23430	COG4172	Belongs to the ABC transporter superfamily
KW548_23440	COG1067	ATP-dependent peptidase activity
KW548_23445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KW548_23460	COG4166	transmembrane transport
KW548_23465	COG4174	ABC transporter (Permease)
KW548_23475	COG4172	Belongs to the ABC transporter superfamily
KW548_23505	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KW548_23510	COG4605	iron ion homeostasis
KW548_23515	COG4604	ABC transporter, ATP-binding protein
KW548_23535	COG2223	nitrite transmembrane transporter activity
KW548_23545	COG2203	Gaf domain
KW548_23545	COG2199	diguanylate cyclase activity
KW548_23550	COG3706	GGDEF domain
KW548_23575	COG0739	heme binding
KW548_23675	COG0515	serine threonine protein kinase
KW548_23675	COG2815	serine threonine protein kinase
KW548_23710	COG1522	sequence-specific DNA binding
KW548_23760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KW548_23780	COG0183	Belongs to the thiolase family
KW548_23800	COG2814	Major facilitator Superfamily
KW548_23805	COG3240	lipase activity
KW548_23825	COG0446	pyridine nucleotide-disulphide oxidoreductase
KW548_23850	COG1328	CTP reductase activity
KW548_23855	COG0602	queuosine metabolic process
KW548_23865	COG0189	ligase activity
KW548_23865	COG4067	protein conserved in archaea
KW548_23875	COG0545	Peptidyl-prolyl cis-trans isomerase
KW548_23895	COG0247	lactate metabolic process
KW548_23905	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KW548_23910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KW548_23915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KW548_23925	COG2926	Belongs to the UPF0265 family
KW548_23930	COG3132	Protein of unknown function, DUF480
KW548_23935	COG2827	Endonuclease containing a URI domain
KW548_23945	COG1879	ABC-type sugar transport system periplasmic component
KW548_23950	COG0784	Response regulator, receiver
KW548_23950	COG5002	protein histidine kinase activity
KW548_24005	COG0484	heat shock protein binding
KW548_24015	COG5001	Diguanylate cyclase
KW548_24015	COG3300	MHYT domain
KW548_24030	COG4181	ATPase activity
KW548_24035	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KW548_24040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KW548_24055	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KW548_24075	COG3069	C4-dicarboxylate transmembrane transporter activity
KW548_24095	COG3038	cytochrome b561
KW548_24100	COG2353	YceI-like domain
KW548_24105	COG2116	formate transmembrane transporter activity
KW548_24110	COG0583	DNA-binding transcription factor activity
KW548_24125	COG0737	Belongs to the 5'-nucleotidase family
KW548_24170	COG2050	protein possibly involved in aromatic compounds catabolism
KW548_24180	COG4533	DNA binding
KW548_24190	COG4771	TonB-dependent receptor
KW548_24190	COG1629	transport
KW548_24200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KW548_24200	COG1042	CoA-binding domain protein
KW548_24200	COG0045	succinate-CoA ligase (ADP-forming) activity
KW548_24205	COG3266	domain, Protein
KW548_24225	COG0023	Translation Initiation Factor
KW548_24290	COG3140	Belongs to the UPF0181 family
KW548_24305	COG0745	RESPONSE REGULATOR receiver
KW548_24315	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KW548_24320	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KW548_24350	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KW548_24355	COG4149	molybdate abc transporter
KW548_24360	COG0725	ABC transporter, periplasmic molybdate-binding protein
KW548_24380	COG1609	Transcriptional regulator
KW548_24385	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW548_24385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KW548_24390	COG1105	Belongs to the carbohydrate kinase PfkB family
KW548_24405	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KW548_24410	COG2207	Transcriptional regulator
KW548_24415	COG1979	alcohol dehydrogenase
KW548_24425	COG0784	Response regulator, receiver
KW548_24425	COG2198	Histidine kinase
KW548_24425	COG2205	protein histidine kinase activity
KW548_24430	COG1879	ABC-type sugar transport system periplasmic component
KW548_24435	COG1803	Methylglyoxal synthase
KW548_24440	COG0800	Aldolase
KW548_24465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KW548_24470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KW548_24475	COG0840	transmembrane signaling receptor activity
KW548_24480	COG0583	DNA-binding transcription factor activity
KW548_24485	COG3048	D-serine ammonia-lyase activity
KW548_24520	COG0513	Belongs to the DEAD box helicase family
KW548_24530	COG0814	amino acid
KW548_24535	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KW548_24535	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KW548_24540	COG0513	Belongs to the DEAD box helicase family
KW548_24555	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KW548_24565	COG2897	thiosulfate sulfurtransferase activity
KW548_24575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KW548_24580	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KW548_24585	COG1522	sequence-specific DNA binding
KW548_24600	COG5001	Diguanylate cyclase
KW548_24600	COG4251	negative regulation of phosphorylation
KW548_24600	COG3706	GGDEF domain
KW548_24600	COG2203	Gaf domain
KW548_24610	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KW548_24625	COG0523	cobalamin synthesis protein
KW548_24650	COG0419	ATPase involved in DNA repair
KW548_24655	COG0420	3'-5' exonuclease activity
KW548_24660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KW548_24665	COG3118	belongs to the thioredoxin family
KW548_24710	COG2315	Protein conserved in bacteria
KW548_24740	COG3706	GGDEF domain
KW548_24760	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase