locus-tag	class	description
D0812_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
D0812_00015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
D0812_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
D0812_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D0812_00030	ENOG4108ZNX	Heat shock protein
D0812_00035	ENOG4105JKW	Valine--pyruvate aminotransferase
D0812_00110	ENOG4105EB3	Histidine kinase
D0812_00120	ENOG4107T9C	Alpha amylase catalytic region
D0812_00125	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
D0812_00130	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
D0812_00145	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
D0812_00160	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
D0812_00165	ENOG4105CHU	acetyl-coa acetyltransferase
D0812_00170	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D0812_00175	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
D0812_00180	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D0812_00185	ENOG4108RR8	protoporphyrinogen oxidase
D0812_00225	ENOG4105E3B	Multicopper oxidase
D0812_00230	ENOG4105WMR	Protein CrcB homolog
D0812_00235	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
D0812_00245	ENOG4105D06	uba thif-type nad fad binding protein
D0812_00250	ENOG4105WHD	thiamine biosynthesis protein ThiS
D0812_00255	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
D0812_00260	ENOG4105D41	biosynthesis protein thiH
D0812_00265	ENOG4105DC7	peptidase M24
D0812_00265	ENOG4105DC7	peptidase M24
D0812_00270	ENOG4105G2Y	Transcriptional regulator
D0812_00275	ENOG4105CNH	Multidrug resistance protein MdtL
D0812_00295	ENOG4105E18	UPF0276 protein
D0812_00305	ENOG4105C4R	Atp-dependent dna helicase
D0812_00315	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D0812_00330	ENOG4105FR1	rard protein
D0812_00335	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D0812_00350	ENOG4105EX9	Membrane
D0812_00360	ENOG4105C9X	ppx gppa phosphatase
D0812_00365	ENOG4105C1J	atp-dependent rna helicase
D0812_00370	ENOG4105K63	Thioredoxin
D0812_00375	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
D0812_00385	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
D0812_00390	ENOG4108ZIT	Ferredoxin, 2FE-2S
D0812_00395	ENOG4107QK7	reductase
D0812_00440	ENOG4105ECF	c-methyltransferase
D0812_00445	ENOG41076E6	Uroporphyrinogen-III Synthase
D0812_00450	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
D0812_00455	ENOG4107T0K	Adenylate cyclase
D0812_00460	ENOG4105XQ6	frataxin-like protein
D0812_00470	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D0812_00475	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
D0812_00485	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D0812_00490	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
D0812_00495	ENOG4105BZU	Histidine kinase
D0812_00500	ENOG4106IUH	DTW domain containing protein
D0812_00515	ENOG4105DQF	Hydrolase
D0812_00520	ENOG4108EUD	Lysophospholipase
D0812_00525	ENOG410829K	Lysine exporter protein (Lyse ygga)
D0812_00530	ENOG4105D58	Diguanylate phosphodiesterase
D0812_00535	ENOG41082YX	Transcriptional regulator, arsr family
D0812_00540	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D0812_00595	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
D0812_00605	ENOG4106H78	methyltransferase
D0812_00610	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
D0812_00610	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
D0812_00615	ENOG4105CAK	Cell division ATP-binding protein ftsE
D0812_00620	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
D0812_00625	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D0812_00630	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
D0812_00635	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
D0812_00640	ENOG4105X6C	Flagellar basal body-associated protein FliL
D0812_00645	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
D0812_00650	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
D0812_00655	ENOG4105E55	glycerol-3-phosphate acyltransferase
D0812_00665	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
D0812_00675	ENOG4107R73	Mate efflux family protein
D0812_00680	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
D0812_00695	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
D0812_00700	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D0812_00710	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
D0812_00780	ENOG4105JIM	Phosphatidylserine synthase
D0812_00790	ENOG4105D4A	Cell wall formation (By similarity)
D0812_00795	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
D0812_00800	ENOG4105CS9	pantothenic acid kinase
D0812_00825	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D0812_00835	ENOG4105PM1	preprotein translocase subunit SecE
D0812_00840	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
D0812_00845	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
D0812_00850	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
D0812_00855	ENOG4108VZM	50s ribosomal protein L10
D0812_00860	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
D0812_00865	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D0812_00870	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D0812_00880	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
D0812_00885	ENOG4105E09	nadh pyrophosphatase
D0812_00890	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
D0812_00895	ENOG4108RG0	uracil-dna glycosylase
D0812_00900	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
D0812_00905	ENOG4105R2J	Conserved Protein
D0812_00925	ENOG4105C12	Phosphoribosylglycinamide synthetase
D0812_00930	ENOG4105DC1	bifunctional purine biosynthesis protein purh
D0812_00935	ENOG4105W1Y	Transcriptional regulator
D0812_00940	ENOG4108M3R	transcriptional activator CadC
D0812_00950	ENOG4105D5Q	Arginine ornithine antiporter
D0812_00955	ENOG4105CXN	decarboxylase
D0812_01000	ENOG4105BZU	Histidine kinase
D0812_01005	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
D0812_01010	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D0812_01015	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D0812_01025	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D0812_01030	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
D0812_01035	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
D0812_01040	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D0812_01055	ENOG4105D8G	Major Facilitator superfamily
D0812_01060	ENOG4105BZU	Histidine kinase
D0812_01065	ENOG4105C9Q	fumarate hydratase class II
D0812_01080	ENOG4107QN1	sodium solute
D0812_01090	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
D0812_01100	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
D0812_01105	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
D0812_01110	ENOG4108IJ0	Aspartate ammonia-lyase
D0812_01115	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
D0812_01120	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
D0812_01130	ENOG4105E0F	Histidine kinase
D0812_01135	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D0812_01140	ENOG4108SPG	Periplasmic Protein
D0812_01145	ENOG41076HS	cation diffusion facilitator family transporter
D0812_01150	ENOG4105CTQ	phosphohexokinase
D0812_01155	ENOG4107QI1	Mate efflux family protein
D0812_01160	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
D0812_01165	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D0812_01180	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
D0812_01185	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
D0812_01200	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
D0812_01205	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
D0812_01220	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
D0812_01230	ENOG41062JF	Transcriptional regulator
D0812_01240	ENOG41063SB	peptidase
D0812_01245	ENOG4105D7W	serine acetyltransferase
D0812_01250	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
D0812_01255	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
D0812_01260	ENOG4107YZP	Rhodanese domain protein
D0812_01265	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D0812_01275	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_01280	ENOG4105C8P	)-transporter
D0812_01290	ENOG4105DJ4	phosphatidylserine decarboxylase
D0812_01295	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
D0812_01300	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
D0812_01375	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
D0812_01380	ENOG4105K8N	protein family UPF0079, ATPase
D0812_01385	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
D0812_01390	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
D0812_01395	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
D0812_01400	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
D0812_01405	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
D0812_01410	ENOG4107QJR	hflk protein
D0812_01415	ENOG4105EPW	hflc protein
D0812_01425	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D0812_01435	ENOG4108UV7	flagellar protein motX
D0812_01440	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
D0812_01445	ENOG4105KPV	Transcriptional regulator
D0812_01450	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
D0812_01455	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D0812_01460	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D0812_01465	ENOG4105C31	Tryptophanyl-tRNA synthetase
D0812_01475	ENOG4105DDQ	anthranilate synthase
D0812_01480	ENOG4105C8Y	Acetylornithine aminotransferase
D0812_01490	ENOG4105C26	Dehydrogenase
D0812_01500	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
D0812_01505	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
D0812_01510	ENOG4105YP7	UPF0270 protein
D0812_01515	ENOG4105DNZ	Alpha Beta Hydrolase
D0812_01525	ENOG4105C5H	ABC transporter
D0812_01535	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D0812_01550	ENOG4108YZY	peptidylprolyl cis-trans isomerase
D0812_01560	ENOG4105D44	asparaginase
D0812_01565	ENOG41069P5	Protein slyX homolog
D0812_01575	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D0812_01580	ENOG4105WWK	YheO domain protein
D0812_01585	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
D0812_01590	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
D0812_01595	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
D0812_01600	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
D0812_01605	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
D0812_01610	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D0812_01615	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D0812_01620	ENOG4105W53	bacterioferritin-associated ferredoxin
D0812_01625	ENOG4108UQY	Iron-storage protein
D0812_01630	ENOG4105C6K	Malic enzyme
D0812_01635	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
D0812_01640	ENOG4105C28	cystathionine
D0812_01645	ENOG4105CFH	Aspartokinase
D0812_01650	ENOG4105SYT	Methylenetetrahydrofolate reductase
D0812_01660	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
D0812_01665	ENOG4105CWC	Acetylornithine deacetylase
D0812_01670	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
D0812_01675	ENOG4105CAS	nag kinase
D0812_01680	ENOG4105CDH	Citrulline--aspartate ligase
D0812_01685	ENOG4105CH7	arginosuccinase
D0812_01700	ENOG4107QN2	dihydrolipoyl dehydrogenase
D0812_01705	ENOG4105EHV	domain protein
D0812_01715	ENOG4108JQC	penicillin-binding protein 1A
D0812_01740	ENOG4105E4G	Type IV pilus
D0812_01745	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
D0812_01750	ENOG4105D49	3-dehydroquinate synthase
D0812_01760	ENOG4105DFE	Dna adenine methylase
D0812_01765	ENOG4105DJV	ribulose-phosphate 3-epimerase
D0812_01770	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
D0812_01775	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
D0812_01780	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
D0812_01785	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
D0812_01795	ENOG4105CDU	Replicative dna helicase
D0812_01800	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D0812_01810	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
D0812_01815	ENOG4107QP8	phosphohexose isomerase
D0812_01825	ENOG4105MYN	Zinc uptake regulation protein
D0812_01830	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D0812_01850	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
D0812_01855	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
D0812_01860	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
D0812_01915	ENOG4105EEQ	Na H antiporter
D0812_01920	ENOG4105C3R	Methionine synthase
D0812_01925	ENOG4105CFH	Aspartokinase
D0812_01935	ENOG4105C5R	Aminotransferase
D0812_01945	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D0812_01950	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
D0812_01955	ENOG41086KC	Transcriptional regulator
D0812_01960	ENOG4108UUM	single-stranded DNA-binding protein
D0812_01965	ENOG41062P1	Diguanylate cyclase phosphodiesterase
D0812_02000	ENOG4107QHF	type ii secretion system protein e
D0812_02005	ENOG4105D7Q	type ii secretion system
D0812_02015	ENOG4108VAU	general secretion pathway protein G
D0812_02055	ENOG4105DFF	Rod shape-determining protein mreb
D0812_02060	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
D0812_02065	ENOG4105VQ7	Rod shape-determining protein MreD
D0812_02070	ENOG4108Z03	MAF-like protein
D0812_02075	ENOG4105C03	ribonuclease
D0812_02080	ENOG4105QD6	exported protein
D0812_02090	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
D0812_02095	ENOG4108IAB	Phoh family
D0812_02100	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
D0812_02105	ENOG4105K3M	)-transporter
D0812_02110	ENOG4105D3G	Pseudouridine synthase
D0812_02115	ENOG4105C5I	Dehydrogenase
D0812_02120	ENOG4105N42	UPF0307 protein
D0812_02125	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
D0812_02130	ENOG4105CJW	magnesium transporter
D0812_02135	ENOG41080Z8	PHOSPHOCARRIER protein
D0812_02140	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
D0812_02145	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
D0812_02150	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
D0812_02155	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D0812_02160	ENOG4108IUZ	ABC transporter
D0812_02165	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
D0812_02175	ENOG4105C2X	Arabinose 5-phosphate isomerase
D0812_02185	ENOG4105DHJ	ABC, transporter
D0812_02190	ENOG4105CY3	ABC transporter, permease
D0812_02195	ENOG4107PE3	Mammalian cell entry related domain protein
D0812_02200	ENOG4105E3I	toluene tolerance
D0812_02210	ENOG4105VFK	BolA family
D0812_02215	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
D0812_02220	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
D0812_02225	ENOG4105KME	endoribonuclease L-psp
D0812_02230	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
D0812_02235	ENOG4105CXT	aspartate transcarbamylase
D0812_02245	ENOG4105DBV	ornithine carbamoyltransferase
D0812_02250	ENOG4105CEU	Arginine dihydrolase
D0812_02265	ENOG4108MJ3	acetyltransferase
D0812_02275	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
D0812_02280	ENOG4105MYG	DNA polymerase iii, chi subunit
D0812_02285	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D0812_02290	ENOG4108M8S	permease YjgP YjgQ family protein
D0812_02295	ENOG4108K5H	permease YjgP YjgQ family protein
D0812_02305	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
D0812_02320	ENOG4105VZJ	PTS System
D0812_02330	ENOG4105VCP	PTS System
D0812_02335	ENOG4105F8D	glycoside hydrolase family 4
D0812_02340	ENOG410901P	UPF0249 protein
D0812_02345	ENOG4105ETE	Transcriptional regulator (LacI family
D0812_02350	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D0812_02400	ENOG4105C26	Dehydrogenase
D0812_02430	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_02475	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
D0812_02480	ENOG4105CEN	a g-specific adenine glycosylase
D0812_02485	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D0812_02495	ENOG4105CSV	Glutaminase
D0812_02500	ENOG4105CSA	Coproporphyrinogen iii oxidase
D0812_02505	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D0812_02515	ENOG4105VZ9	UPF0235 protein
D0812_02520	ENOG4108VIA	integral membrane protein
D0812_02525	ENOG4105II7	pyrroline-5-carboxylate reductase
D0812_02530	ENOG4105DFA	alanine racemase domain protein
D0812_02535	ENOG4105CZX	twitching motility protein
D0812_02540	ENOG4105CZX	twitching motility protein
D0812_02545	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
D0812_02550	ENOG4108UJU	UPF0301 protein
D0812_02555	ENOG4105D7Z	glutathione synthase
D0812_02560	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
D0812_02565	ENOG4105RWS	endonuclease I
D0812_02570	ENOG4105GPY	SprT protein
D0812_02580	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
D0812_02585	ENOG4105CV1	Transketolase (EC 2.2.1.1)
D0812_02595	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D0812_02600	ENOG4105BZA	Phosphoglycerate kinase
D0812_02605	ENOG4105D2N	Aldolase
D0812_02610	ENOG4105D64	Mechanosensitive ion channel
D0812_02625	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
D0812_02630	ENOG4105MPN	Membrane
D0812_02635	ENOG4108JQ1	Dehydrogenase
D0812_02640	ENOG4105E66	phosphoriboisomerase A
D0812_02645	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
D0812_02655	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
D0812_02670	ENOG4105D0A	hydroxylase
D0812_02675	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
D0812_02690	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
D0812_02695	ENOG4105Y75	tpr repeat protein
D0812_02705	ENOG4108IYU	L-aspartate oxidase
D0812_02715	ENOG4105EMN	RNA polymerase sigma factor
D0812_02725	ENOG4105VQK	sigma E regulatory protein, MucB RseB
D0812_02735	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
D0812_02740	ENOG4105C3F	Signal peptidase i
D0812_02745	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
D0812_02750	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
D0812_02755	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
D0812_02760	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
D0812_02765	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
D0812_02770	ENOG4105BZU	Histidine kinase
D0812_02780	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
D0812_02785	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D0812_02790	ENOG4105DXN	mazG family
D0812_02795	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
D0812_02800	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
D0812_02805	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
D0812_02810	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
D0812_02815	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
D0812_02820	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
D0812_02825	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
D0812_02830	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
D0812_02840	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D0812_02845	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D0812_02850	ENOG4107TH8	cina domain protein
D0812_02855	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
D0812_02860	ENOG4105Y3E	Modulates RecA activity (By similarity)
D0812_02865	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D0812_02870	ENOG4105CFH	Aspartokinase
D0812_02875	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
D0812_02955	ENOG41086KC	Transcriptional regulator
D0812_02965	ENOG4107QSA	Oxaloacetate decarboxylase
D0812_02970	ENOG4105D9Q	decarboxylase (Beta subunit)
D0812_02980	ENOG4105W39	Membrane
D0812_02990	ENOG4105D9M	gamma-glutamylcysteine synthetase
D0812_03000	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
D0812_03005	ENOG4108JU6	CBS domain protein
D0812_03010	ENOG4106KVJ	cytochrome C assembly protein
D0812_03015	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D0812_03020	ENOG4105K5M	30s ribosomal protein S16
D0812_03025	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
D0812_03030	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
D0812_03035	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
D0812_03040	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
D0812_03045	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
D0812_03050	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
D0812_03055	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
D0812_03060	ENOG4105D7Q	type ii secretion system
D0812_03065	ENOG4107QHF	type ii secretion system protein e
D0812_03080	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
D0812_03090	ENOG41073TP	transcriptional regulator
D0812_03095	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
D0812_03100	ENOG4107QSN	dihydrolipoamide acetyltransferase
D0812_03105	ENOG4107QN2	dihydrolipoyl dehydrogenase
D0812_03110	ENOG410630P	Transcriptional regulator
D0812_03115	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
D0812_03120	ENOG41077A9	carbonic anhydrase
D0812_03125	ENOG4105CHH	sulfate transporter
D0812_03130	ENOG4105DA5	(ABC) transporter
D0812_03135	ENOG4105E3A	(ABC) transporter
D0812_03140	ENOG4105D1S	lipid A biosynthesis
D0812_03145	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
D0812_03150	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
D0812_03155	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D0812_03160	ENOG4105DJ0	Poly(A) Polymerase
D0812_03165	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
D0812_03170	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0812_03175	ENOG4105PW4	Sugar fermentation stimulation protein homolog
D0812_03180	ENOG4105CQ7	ATP-dependent helicase
D0812_03185	ENOG4105BZ4	penicillin-binding protein
D0812_03190	ENOG4105D78	K07001 NTE family protein
D0812_03195	ENOG4107QIJ	Aconitate hydratase 2
D0812_03200	ENOG4105XTV	UPF0231 protein
D0812_03205	ENOG4108YZA	Nitrogen regulatory protein pii
D0812_03225	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D0812_03240	ENOG4105E2D	ec 3.2.1.52
D0812_03245	ENOG4105RD7	BadF BadG BcrA BcrD
D0812_03255	ENOG4108JQ7	(ABC) transporter
D0812_03260	ENOG4105C3U	ABC transporter
D0812_03265	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D0812_03275	ENOG4107QRA	Extracellular solute-binding protein, family 5
D0812_03280	ENOG4105BZU	Histidine kinase
D0812_03290	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
D0812_03295	ENOG4105F4G	Membrane
D0812_03305	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
D0812_03310	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
D0812_03320	ENOG4105BZS	acriflavin resistance protein
D0812_03325	ENOG4105DR5	peptidase
D0812_03330	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D0812_03340	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
D0812_03345	ENOG4107QE9	Inherit from COG: Membrane
D0812_03350	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D0812_03355	ENOG4105HBR	Rna-binding protein
D0812_03360	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
D0812_03365	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D0812_03370	ENOG4105EEI	dihydropteroate synthase
D0812_03375	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
D0812_03395	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
D0812_03400	ENOG4105CHV	Transcription elongation factor NusA
D0812_03405	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
D0812_03410	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
D0812_03415	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
D0812_03420	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
D0812_03425	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
D0812_03440	ENOG4105C3S	Mate efflux family protein
D0812_03445	ENOG4106RZ4	Peptidase U32
D0812_03450	ENOG4105CFP	Peptidase U32
D0812_03455	ENOG4105BZU	Histidine kinase
D0812_03460	ENOG4105XPQ	lipid carrier protein
D0812_03465	ENOG4108YYD	acetyltransferase
D0812_03485	ENOG4105BZU	Histidine kinase
D0812_03490	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
D0812_03495	ENOG4105EYA	deoxyribonuclease
D0812_03500	ENOG4105D9N	nucleoside
D0812_03505	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
D0812_03510	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
D0812_03515	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
D0812_03520	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
D0812_03530	ENOG4105EAC	phosphoserine phosphatase
D0812_03540	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
D0812_03545	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D0812_03550	ENOG4105ETT	transcriptional Regulator, LysR family
D0812_03585	ENOG4108IQE	Amp-dependent synthetase and ligase
D0812_03590	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
D0812_03665	ENOG4105CDV	Ompa motb domain protein
D0812_03675	ENOG41064T2	transcriptional regulator, lysR family
D0812_03680	ENOG4107WCA	isomerase
D0812_03685	ENOG4107W6W	Conserved Protein
D0812_03690	ENOG4105E5D	amino acid
D0812_03695	ENOG4105FK9	beta-D-galactosidase beta subunit
D0812_03700	ENOG4105CNT	hydrolase family 2
D0812_03705	ENOG4105CQ4	Transcriptional regulator
D0812_03710	ENOG4105CJN	penicillin-binding protein
D0812_03715	ENOG4105CMR	udp-glucose 4-epimerase
D0812_03720	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
D0812_03725	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
D0812_03730	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D0812_03740	ENOG41060NJ	transcriptional regulator
D0812_03745	ENOG4105CI1	PTS System
D0812_03755	ENOG4108Y51	tRNA-binding protein
D0812_03775	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
D0812_03780	ENOG4105E98	transcriptional regulator DeoR family
D0812_03785	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
D0812_03790	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
D0812_03800	ENOG4105CXY	transporter
D0812_03805	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
D0812_03820	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
D0812_03835	ENOG4105X2V	dna damage-inducible protein
D0812_03840	ENOG4105EVZ	LysR family transcriptional regulator
D0812_03850	ENOG4105E68	Sulfatase
D0812_03855	ENOG4105DSY	exodeoxyribonuclease V, gamma
D0812_03860	ENOG4107QKA	exodeoxyribonuclease V beta
D0812_03865	ENOG4107QYX	exodeoxyribonuclease v alpha
D0812_03880	ENOG4107QZM	n-acetylglutamate synthase
D0812_03895	ENOG4105CA3	membrane-bound lytic murein transglycosylase
D0812_03900	ENOG4105CUZ	uba thif-type nad fad binding protein
D0812_03905	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
D0812_03910	ENOG4105C9B	Cysteine desulfurase
D0812_03915	ENOG4107S0N	DJ-1 family
D0812_03920	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
D0812_03925	ENOG4105DRB	nucleoside-specific channel-forming protein
D0812_03945	ENOG4105K6V	RNA polymerase
D0812_03960	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D0812_03970	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
D0812_03975	ENOG4105M85	Bola protein
D0812_03980	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D0812_03985	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D0812_03990	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D0812_03995	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D0812_04000	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D0812_04005	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
D0812_04010	ENOG4105CJ2	(LipO)protein
D0812_04020	ENOG4105BZU	Histidine kinase
D0812_04025	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D0812_04030	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D0812_04035	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D0812_04050	ENOG4105C8J	)-transporter
D0812_04060	ENOG4105W1I	UPF0253 protein
D0812_04070	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
D0812_04075	ENOG4108R96	Methyltransferase, YaeB family
D0812_04080	ENOG4105NRA	50s ribosomal protein l31 type b
D0812_04090	ENOG4105CFC	Transporter
D0812_04100	ENOG4108UPT	UPF0178 protein
D0812_04125	ENOG4105WP7	tRNA pseudouridine synthase C
D0812_04130	ENOG4105DR9	pseudouridine synthase
D0812_04135	ENOG4108T8E	UPF0325 protein
D0812_04140	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
D0812_04145	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
D0812_04150	ENOG4105CE9	30S ribosomal protein S2
D0812_04155	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
D0812_04160	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
D0812_04165	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
D0812_04170	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
D0812_04175	ENOG4105KNE	Phosphatidate cytidylyltransferase
D0812_04180	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
D0812_04185	ENOG4105DZP	Membrane-associated zinc metalloprotease
D0812_04195	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
D0812_04200	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D0812_04205	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D0812_04210	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D0812_04215	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D0812_04220	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D0812_04225	ENOG4105C0B	DNA polymerase III (alpha subunit)
D0812_04230	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
D0812_04235	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D0812_04240	ENOG4105N7H	Cytochrome
D0812_04245	ENOG4108YZA	Nitrogen regulatory protein pii
D0812_04250	ENOG4107NA1	Endonuclease Exonuclease phosphatase
D0812_04260	ENOG4105E9H	Lytic Murein transglycosylase
D0812_04265	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
D0812_04270	ENOG4105D1A	Methyltransferase
D0812_04275	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D0812_04280	ENOG4107RZZ	dna polymerase iii epsilon subunit
D0812_04300	ENOG4107QPN	acyl-Coa dehydrogenase
D0812_04305	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
D0812_04310	ENOG4105E7A	Glutamine amidotransferase
D0812_04315	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
D0812_04320	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
D0812_04325	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
D0812_04330	ENOG4105C2W	permease
D0812_04345	ENOG4105CS1	NAD(P)H quinone oxidoreductase
D0812_04350	ENOG4105K89	arsenate reductase
D0812_04355	ENOG4105ERG	peptidase m48, ste24p
D0812_04370	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D0812_04375	ENOG4105RH4	Glycine cleavage system transcriptional repressor
D0812_04385	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D0812_04400	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D0812_04405	ENOG4105KUZ	arsenate reductase
D0812_04425	ENOG4105QZU	Inner membrane protein YfeZ
D0812_04430	ENOG4105EZR	dyp-type peroxidase family protein
D0812_04435	ENOG4108K2B	transcriptional regulator
D0812_04440	ENOG4105F8D	glycoside hydrolase family 4
D0812_04445	ENOG4105CT4	transporter
D0812_04455	ENOG4105I03	Flagellin
D0812_04465	ENOG4105I03	Flagellin
D0812_04470	ENOG4105I03	Flagellin
D0812_04475	ENOG41063QE	flagellar protein FlaG
D0812_04480	ENOG4107BRV	flagellar capping protein
D0812_04490	ENOG4105MQ3	flagellar protein FliS
D0812_04495	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_04500	ENOG4105BZU	Histidine kinase
D0812_04505	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_04510	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
D0812_04515	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
D0812_04520	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D0812_04530	ENOG4108JIR	Flagellum-specific ATP synthase
D0812_04555	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D0812_04560	ENOG4105DD5	Flagellar motor switch protein
D0812_04565	ENOG4105VTB	flagellar biosynthesis protein fliO
D0812_04570	ENOG4105CN7	Flagellar biosynthetic protein FliP
D0812_04575	ENOG4105VS8	Flagellar biosynthetic protein fliq
D0812_04580	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
D0812_04585	ENOG4105D00	flagellar biosynthetic protein flhB
D0812_04590	ENOG4105D7B	Flagellar biosynthesis protein flha
D0812_04595	ENOG4105FZW	flagellar biosynthesis regulator FlhF
D0812_04600	ENOG4107R21	site-determining protein
D0812_04605	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D0812_04610	ENOG4108VYJ	response regulator receiver protein
D0812_04615	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
D0812_04620	ENOG4105CBS	Chea signal transduction histidine kinase
D0812_04625	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D0812_04630	ENOG4107QJE	Chromosome Partitioning Protein
D0812_04640	ENOG4108V3W	Chemotaxis protein, CheW
D0812_04650	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
D0812_04655	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
D0812_04660	ENOG41060IM	Heme exporter protein
D0812_04670	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
D0812_04675	ENOG4105DA4	cytochrome c-type biogenesis protein
D0812_04680	ENOG4107QX9	Thiol disulfide interChange protein
D0812_04685	ENOG4108M1T	Cytochrome c-type biogenesis protein
D0812_04690	ENOG4105KWW	Biogenesis protein
D0812_04695	ENOG410903C	(LipO)protein
D0812_04700	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
D0812_04705	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
D0812_04720	ENOG4105CHU	acetyl-coa acetyltransferase
D0812_04725	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D0812_04730	ENOG4107QXK	peptidase
D0812_04735	ENOG4108BY2	phosphohistidine phosphatase
D0812_04740	ENOG4108DG9	Smr protein MutS2
D0812_04745	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
D0812_04750	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
D0812_04755	ENOG4105EN6	Membrane
D0812_04760	ENOG4108BPE	-transporting atpase
D0812_04765	ENOG4105MH2	YfcL protein
D0812_04780	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
D0812_04785	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D0812_04795	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
D0812_04800	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
D0812_04810	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
D0812_04820	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
D0812_04825	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
D0812_04830	ENOG4108S3P	Sporulation domain protein
D0812_04835	ENOG4105E96	Colicin v production protein
D0812_04840	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
D0812_04845	ENOG4105EJC	lysr family transcriptional regulator
D0812_04850	ENOG4105I93	response regulator
D0812_04860	ENOG4105WD1	Membrane
D0812_04865	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
D0812_04870	ENOG4107QMP	dna polymerase iii subunits gamma and tau
D0812_04875	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
D0812_04880	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
D0812_04885	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
D0812_04890	ENOG4105C44	Serine transporter
D0812_04900	ENOG4105CEM	UPF0597 protein
D0812_04905	ENOG4105WWK	YheO domain protein
D0812_04910	ENOG4105KRS	Proteinase inhibitor
D0812_04920	ENOG4108ZZ3	UPF0260 protein
D0812_04925	ENOG4105Y3U	Transglycosylase-associated protein
D0812_04930	ENOG4105D0C	transport protein
D0812_04935	ENOG4105CVK	Glutamate decarboxylase
D0812_04950	ENOG4108UYE	Lactoylglutathione lyase
D0812_04960	ENOG4105G6Z	alkaline phosphatase
D0812_04975	ENOG4105DHI	Methyltransferase
D0812_04980	ENOG4107SDU	Methyl-accepting chemotaxis
D0812_04995	ENOG4105DSB	aldose 1-epimerase
D0812_05000	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D0812_05005	ENOG4105E0X	reductase
D0812_05015	ENOG4105VUT	cytoplasmic protein
D0812_05020	ENOG4105HDK	L-asparaginase
D0812_05025	ENOG4105D07	Signal peptide peptidase, SppA
D0812_05030	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D0812_05035	ENOG41069NU	Nitroreductase
D0812_05040	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D0812_05050	ENOG4108RU0	short-chain dehydrogenase reductase
D0812_05055	ENOG4105DGU	Histone deacetylase
D0812_05060	ENOG4108M3P	Membrane
D0812_05075	ENOG4105E68	Sulfatase
D0812_05080	ENOG4105YDX	UPF0352 protein
D0812_05085	ENOG4106V8H	Nucleoid-associated protein
D0812_05100	ENOG4105DFD	Na H antiporter
D0812_05105	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
D0812_05110	ENOG4105X0D	Fimbrial protein
D0812_05115	ENOG4105EYW	Ion transport protein
D0812_05120	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
D0812_05125	ENOG4108EKI	Dehydrogenase
D0812_05140	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D0812_05145	ENOG4105M2J	Glutaredoxin
D0812_05150	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D0812_05260	ENOG4105W5Q	DNA repair protein (RadC
D0812_05330	ENOG4108PCE	TRANSFER protein
D0812_05390	ENOG4105D3Y	Na H antiporter
D0812_05395	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
D0812_05400	ENOG4105EIY	sodium-type flagellar protein motY
D0812_05405	ENOG4106WH9	Protein of unknown function (DUF2753)
D0812_05410	ENOG4108UYE	Lactoylglutathione lyase
D0812_05440	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
D0812_05455	ENOG4105CS6	Rhs element vgr protein
D0812_05470	ENOG4105E6M	Sulphatase-modifying factor protein
D0812_05485	ENOG4105C7H	Helicase, RecD TraA family
D0812_05515	ENOG4105CSM	endonuclease III
D0812_05520	ENOG4105DZB	Electron transport complex
D0812_05525	ENOG4108UQQ	Electron transport complex
D0812_05530	ENOG4105D6A	Electron transport complex
D0812_05540	ENOG4108R3D	Electron transport complex
D0812_05545	ENOG4105DGN	Electron transport complex
D0812_05550	ENOG4105C6N	Formate acetyltransferase
D0812_05565	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
D0812_05570	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_05580	ENOG4105CHW	UPF0052 protein
D0812_05585	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D0812_05590	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
D0812_05595	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D0812_05600	ENOG4105M00	molybdopterin converting factor, subunit 1
D0812_05605	ENOG4108ZAF	Molybdopterin
D0812_05610	ENOG4107QSI	ABC, transporter
D0812_05615	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D0812_05620	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D0812_05625	ENOG4105C3U	ABC transporter
D0812_05630	ENOG4108JQ7	(ABC) transporter
D0812_05635	ENOG4105CHF	Glutathione S-transferase
D0812_05640	ENOG4107PU6	Membrane
D0812_05650	ENOG4108DNC	Involved in acetate metabolism (By similarity)
D0812_05655	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
D0812_05660	ENOG4105PQ6	UPF0208 membrane protein
D0812_05675	ENOG4105C7J	ABC transporter, permease
D0812_05680	ENOG4108JJB	ABC transporter
D0812_05685	ENOG4107R28	alpha amylase, catalytic region
D0812_05695	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
D0812_05700	ENOG4106RHG	Yeca family
D0812_05705	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
D0812_05710	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D0812_05715	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
D0812_05740	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
D0812_05745	ENOG4105D1F	ATP-binding protein
D0812_05750	ENOG4105DBI	uridine monophosphokinase
D0812_05760	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
D0812_05770	ENOG4105CHH	sulfate transporter
D0812_05780	ENOG4105C03	ribonuclease
D0812_05785	ENOG4105EI2	Pseudouridine synthase
D0812_05790	ENOG4108UHJ	MAF-like protein
D0812_05795	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
D0812_05800	ENOG4105VGS	50s ribosomal protein l32
D0812_05805	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
D0812_05810	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D0812_05815	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
D0812_05820	ENOG4105CHR	reductase
D0812_05825	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D0812_05830	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D0812_05840	ENOG4105HHA	aminodeoxychorismate lyase
D0812_05845	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
D0812_05850	ENOG4107QRG	dna polymerase iii
D0812_05855	ENOG4105F8V	Hydrolase, tatD family
D0812_05860	ENOG4105CI1	PTS System
D0812_05875	ENOG4105C8J	)-transporter
D0812_05890	ENOG4108NRW	Phospholipase, patatin family
D0812_05895	ENOG4105CA9	Pyruvate kinase
D0812_05900	ENOG4105DAG	ROK family
D0812_05905	ENOG4107R88	Chemotaxis protein (CheV)
D0812_05910	ENOG4105C0B	DNA polymerase III (alpha subunit)
D0812_05925	ENOG4105UBK	short-chain dehydrogenase reductase
D0812_05930	ENOG4105ERU	peptidase
D0812_05940	ENOG4105CAT	Cytidine monophosphate kinase
D0812_05945	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
D0812_05950	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D0812_05955	ENOG4105Q4A	inner membrane protein yciS
D0812_05960	ENOG4105CFV	Tetratricopeptide repeat protein
D0812_05965	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
D0812_05970	ENOG4108J59	Extracellular solute-binding protein, family 5
D0812_06030	ENOG4105ENH	Sulfatase
D0812_06035	ENOG4108WUH	Transcriptional regulator, TetR family
D0812_06040	ENOG4108Q2G	(LipO)protein
D0812_06045	ENOG4105DY2	Paraquat-inducible protein b
D0812_06050	ENOG4105F1S	paraquat-inducible protein a
D0812_06055	ENOG41060NJ	transcriptional regulator
D0812_06060	ENOG4105NQN	cytochrome C
D0812_06065	ENOG41090Y2	cytochrome C
D0812_06070	ENOG4105DB1	molybdopterin oxidoreductase
D0812_06075	ENOG4106WHD	Tetrathionate reductase
D0812_06080	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
D0812_06085	ENOG4106AFQ	Histidine kinase
D0812_06090	ENOG4108ZXC	Two component transcriptional regulator, luxr family
D0812_06105	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
D0812_06115	ENOG4105CT4	transporter
D0812_06120	ENOG4105DHT	Metal Dependent Phosphohydrolase
D0812_06125	ENOG4105JQN	Transcriptional regulator
D0812_06135	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
D0812_06140	ENOG4105N6Y	Thioredoxin
D0812_06150	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
D0812_06160	ENOG4108MK9	spermidine N(1)-acetyltransferase
D0812_06170	ENOG41080VW	acetyltransferase
D0812_06210	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
D0812_06220	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D0812_06225	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D0812_06230	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D0812_06240	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D0812_06255	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
D0812_06265	ENOG4105J12	Multidrug resistance protein mdtN
D0812_06270	ENOG4105EQ2	LysR family Transcriptional regulator
D0812_06310	ENOG41062D9	Histidine kinase
D0812_06315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D0812_06325	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
D0812_06335	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_06340	ENOG4105WWK	YheO domain protein
D0812_06345	ENOG4105KME	endoribonuclease L-psp
D0812_06350	ENOG4107R6U	sodium dicarboxylate symporter
D0812_06355	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
D0812_06375	ENOG4105CCT	upf0313 protein
D0812_06395	ENOG4105DZ2	Transcriptional regulator
D0812_06400	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
D0812_06410	ENOG4105K9H	YciI-like protein
D0812_06415	ENOG4105NAU	thioesterase Superfamily protein
D0812_06420	ENOG4107835	probably involved in intracellular septation (By similarity)
D0812_06430	ENOG4105BZU	Histidine kinase
D0812_06440	ENOG4105CK2	sodium dicarboxylate symporter
D0812_06445	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
D0812_06450	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D0812_06455	ENOG4105DK0	Indole-3-glycerol phosphate synthase
D0812_06460	ENOG4108I0Q	anthranilate phosphoribosyltransferase
D0812_06465	ENOG4105DDQ	anthranilate synthase
D0812_06470	ENOG4105CRQ	synthase (Component I)
D0812_06480	ENOG4105DB7	PHP domain protein
D0812_06485	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
D0812_06495	ENOG4105FE9	pseudouridine synthase
D0812_06500	ENOG4108W5H	UPF0263 protein
D0812_06515	ENOG4105CQ2	DNA polymerase
D0812_06520	ENOG4105WH1	Two component transcriptional regulator luxr family
D0812_06525	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
D0812_06565	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
D0812_06590	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D0812_06595	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D0812_06605	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D0812_06610	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D0812_06625	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
D0812_06635	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
D0812_06640	ENOG4105DVI	reductase, NrfD
D0812_06645	ENOG4105DA4	cytochrome c-type biogenesis protein
D0812_06650	ENOG4107QX9	Thiol disulfide interChange protein
D0812_06655	ENOG4108DMF	Cytochrome C biogenesis protein
D0812_06665	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
D0812_06690	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
D0812_06695	ENOG4105EAQ	(twin-arginine translocation) pathway signal
D0812_06700	ENOG4105C5X	domain protein
D0812_06715	ENOG4105CH5	extracellular solute-binding protein, family 7
D0812_06725	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D0812_06740	ENOG41067TZ	transcriptional regulator, MarR family
D0812_06745	ENOG4105C94	Transporter
D0812_06750	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_06770	ENOG4105CGF	Aromatic amino acid aminotransferase
D0812_06775	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D0812_06780	ENOG4107RUZ	Sss sodium solute transporter superfamily
D0812_06790	ENOG4105ETE	Transcriptional regulator (LacI family
D0812_06805	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D0812_06820	ENOG4105C5S	asparaginyl-tRNA synthetase
D0812_06825	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_06830	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
D0812_06835	ENOG4105WH1	Two component transcriptional regulator luxr family
D0812_06845	ENOG4105BZU	Histidine kinase
D0812_06850	ENOG4105EJQ	L-serine dehydratase
D0812_06855	ENOG4105C44	Serine transporter
D0812_06870	ENOG4105BZU	Histidine kinase
D0812_06875	ENOG4105CRQ	synthase (Component I)
D0812_06890	ENOG4105CM6	amino acid regulated cytosolic protein
D0812_06895	ENOG4106K28	UPF0283 membrane protein
D0812_06905	ENOG4105D9U	N-acetyltransferase
D0812_07095	ENOG4108MTT	Glutamate-rich protein grpB
D0812_07325	ENOG4108R4U	Hnh endonuclease
D0812_07500	ENOG4105KVH	Transcriptional regulator
D0812_07510	ENOG4105EC3	peptidase S51, dipeptidase E
D0812_07530	ENOG4107RJ1	sodium solute
D0812_07545	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D0812_07555	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
D0812_07560	ENOG4105ETE	Transcriptional regulator (LacI family
D0812_07565	ENOG4105CNV	Aldolase
D0812_07570	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
D0812_07575	ENOG4105CHR	reductase
D0812_07600	ENOG4107WJM	-acetyltransferase
D0812_07605	ENOG4105C8P	)-transporter
D0812_07610	ENOG4105BZU	Histidine kinase
D0812_07615	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_07620	ENOG4105BZU	Histidine kinase
D0812_07625	ENOG4105CPI	Metal Dependent Phosphohydrolase
D0812_07630	ENOG410829K	Lysine exporter protein (Lyse ygga)
D0812_07635	ENOG4105G0K	glycine radical enzyme YjjI family
D0812_07640	ENOG41076CZ	activating enzyme
D0812_07650	ENOG4105EE5	Membrane protein terC
D0812_07660	ENOG4105DHT	Metal Dependent Phosphohydrolase
D0812_07670	ENOG4105BZU	Histidine kinase
D0812_07685	ENOG4105E0U	tyrosine-specific transport protein
D0812_07705	ENOG4105BZ1	(ABC) transporter
D0812_07710	ENOG4105BZ1	(ABC) transporter
D0812_07725	ENOG4105CR8	Transcriptional regulator
D0812_07750	ENOG4105CFG	Acts as a chaperone (By similarity)
D0812_07755	ENOG4105CFG	Acts as a chaperone (By similarity)
D0812_07765	ENOG4105BZU	Histidine kinase
D0812_07790	ENOG4105D4Y	metalloprotease
D0812_07800	ENOG4107QY8	reductase
D0812_07805	ENOG4105QAX	Iron-sulfur
D0812_07810	ENOG4107KGK	dmso reductase anchor subunit
D0812_07815	ENOG4108NEM	leader-binding protein dmsD
D0812_07825	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
D0812_07830	ENOG4105CQ7	ATP-dependent helicase
D0812_07855	ENOG41090FY	type IV pilus biogenesis stability protein PilW
D0812_07860	ENOG4105CVG	Homoserine O-transsuccinylase
D0812_07890	ENOG4105E5D	amino acid
D0812_07895	ENOG4105N14	lysine exporter protein LysE YggA
D0812_07900	ENOG4105CR8	Transcriptional regulator
D0812_07905	ENOG4107S9F	NmrA family
D0812_07910	ENOG4105EJC	lysr family transcriptional regulator
D0812_07915	ENOG4105D1S	lipid A biosynthesis
D0812_07920	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
D0812_07930	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
D0812_07945	ENOG4105CTD	carboxy-peptidase
D0812_07950	ENOG410829K	Lysine exporter protein (Lyse ygga)
D0812_07960	ENOG4107QMS	site-determining protein
D0812_07980	ENOG4105BZG	amino acid carrier protein
D0812_08000	ENOG41063TF	transcriptional regulator (AraC
D0812_08035	ENOG4105CR8	Transcriptional regulator
D0812_08040	ENOG4105E0M	Sulfatase
D0812_08045	ENOG4105C8N	cysteinyl-tRNA synthetase
D0812_08050	ENOG4107QI1	Mate efflux family protein
D0812_08055	ENOG41080XQ	Signal transduction protein with cbs domains
D0812_08065	ENOG4105C94	Transporter
D0812_08070	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
D0812_08075	ENOG4108JPW	Aminotransferase
D0812_08080	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
D0812_08085	ENOG4105CZK	Aspartate kinase
D0812_08095	ENOG4105CV8	reductase
D0812_08100	ENOG4105HEI	LysR family (Transcriptional regulator
D0812_08105	ENOG4105CA0	peroxidase
D0812_08110	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D0812_08115	ENOG4105HEI	LysR family (Transcriptional regulator
D0812_08135	ENOG4108K2B	transcriptional regulator
D0812_08140	ENOG4108RNG	Permease of the drug metabolite transporter
D0812_08145	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
D0812_08150	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
D0812_08165	ENOG4105CMR	udp-glucose 4-epimerase
D0812_08185	ENOG4107V40	secretion protein, HlyD family
D0812_08200	ENOG4105HVQ	Regulatory factor of maltose metabolism
D0812_08210	ENOG4108WTW	DNA transposition protein
D0812_08240	ENOG4106V8H	Nucleoid-associated protein
D0812_08265	ENOG4105K5B	UPF0225 protein
D0812_08460	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
D0812_08475	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D0812_08480	ENOG4105C2D	reductase
D0812_08515	ENOG4105C84	Histidine ammonia-lyase
D0812_08520	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
D0812_08525	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D0812_08545	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D0812_08590	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
D0812_08600	ENOG4105E4F	Isochorismate synthase
D0812_08605	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
D0812_08610	ENOG4105WQI	isochorismatase
D0812_08615	ENOG4105CEY	Amp-dependent synthetase and ligase
D0812_08615	ENOG4105CEY	Amp-dependent synthetase and ligase
D0812_08630	ENOG4105D05	Receptor
D0812_08640	ENOG4105C1J	atp-dependent rna helicase
D0812_08645	ENOG4105C94	Transporter
D0812_08650	ENOG4107ZYR	domain protein
D0812_08670	ENOG4105CNG	UPF0061 protein
D0812_08675	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
D0812_08680	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
D0812_08685	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D0812_08695	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_08700	ENOG4105CQZ	Histidine kinase
D0812_08705	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
D0812_08710	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D0812_08715	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
D0812_08720	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D0812_08725	ENOG4105K70	DNA-binding protein
D0812_08730	ENOG4105EIN	peptidylprolyl cis-trans isomerase
D0812_08735	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
D0812_08750	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
D0812_08755	ENOG4105DK2	UPF0207 protein
D0812_08760	ENOG4105CHM	Aminotransferase
D0812_08765	ENOG4105E4F	Isochorismate synthase
D0812_08770	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
D0812_08775	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
D0812_08780	ENOG4108IPT	Naphthoate synthase
D0812_08785	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
D0812_08790	ENOG4105CEY	Amp-dependent synthetase and ligase
D0812_08795	ENOG4105CI1	PTS System
D0812_08800	ENOG4105ETT	transcriptional Regulator, LysR family
D0812_08810	ENOG4105HMI	Membrane
D0812_08865	ENOG4105BZS	acriflavin resistance protein
D0812_08885	ENOG4108XM1	transcriptional regulator AsnC family
D0812_08895	ENOG4105C29	acyl-CoA thioesterase
D0812_08900	ENOG4108MNP	Glycoprotein polysaccharide metabolism
D0812_08915	ENOG4108KHX	Diguanylate cyclase
D0812_08945	ENOG410890F	Dynamin family
D0812_08975	ENOG4108Z4U	Ferredoxin
D0812_08980	ENOG4105DZ0	fad dependent oxidoreductase
D0812_08985	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D0812_09000	ENOG4107SXA	Phosphorylase
D0812_09010	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_09015	ENOG4105K59	histidine triad (HIT) protein
D0812_09040	ENOG4105D0Y	UPF0227 protein
D0812_09045	ENOG4105CEP	NADH dehydrogenase
D0812_09060	ENOG4108JA2	transcriptioN-repair coupling factor
D0812_09070	ENOG4105D60	lipoprotein releasing system transmembrane protein
D0812_09075	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D0812_09080	ENOG4105D60	lipoprotein releasing system transmembrane protein
D0812_09090	ENOG4108EC8	DNA internalization-related competence protein ComEC
D0812_09095	ENOG4105BZ1	(ABC) transporter
D0812_09100	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
D0812_09105	ENOG4105W49	UPF0434 protein
D0812_09110	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
D0812_09115	ENOG4105ED1	spovr family
D0812_09120	ENOG4106AKX	UPF0229 protein
D0812_09125	ENOG4105CYN	Serine protein kinase
D0812_09135	ENOG4105XWI	UPF0304 protein
D0812_09145	ENOG4105F1A	Pyruvate formate-lyase
D0812_09155	ENOG4105C6N	Formate acetyltransferase
D0812_09170	ENOG4108JEH	abc transporter atp-binding protein
D0812_09175	ENOG4105E89	ABC transporter
D0812_09180	ENOG4105DSP	amino acid AbC transporter
D0812_09200	ENOG4108JJ6	Type I secretion system ATPase
D0812_09205	ENOG4105CGK	Exodeoxyribonuclease III
D0812_09210	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_09215	ENOG4106428	Protein of unknown function (DUF2496)
D0812_09220	ENOG4108URS	primosomal replication protein n''
D0812_09225	ENOG4105EJ9	Membrane
D0812_09230	ENOG4105DVT	helicase
D0812_09245	ENOG4108R99	pseudouridine synthase
D0812_09255	ENOG4105VEQ	Cold shock protein
D0812_09260	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
D0812_09265	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D0812_09270	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
D0812_09275	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
D0812_09280	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
D0812_09290	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
D0812_09295	ENOG4105RKX	Protein of unknown function (DUF2498)
D0812_09300	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D0812_09305	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
D0812_09310	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D0812_09330	ENOG4105HP8	regulator of competence-specific genes
D0812_09335	ENOG4105ETE	Transcriptional regulator (LacI family
D0812_09340	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
D0812_09345	ENOG4106WF9	DNA-binding transcriptional regulator TorR
D0812_09350	ENOG4107S90	membrAne
D0812_09355	ENOG4106371	Methyltransferase
D0812_09360	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
D0812_09365	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
D0812_09370	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
D0812_09375	ENOG4108ZX5	transcriptional regulator
D0812_09380	ENOG4107RGH	Aldehyde dehydrogenase
D0812_09385	ENOG4105CEY	Amp-dependent synthetase and ligase
D0812_09410	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D0812_09420	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
D0812_09425	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
D0812_09430	ENOG41081XQ	Conserved Protein
D0812_09435	ENOG4105C9M	aspartyl-trna synthetase
D0812_09440	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
D0812_09445	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_09450	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
D0812_09455	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D0812_09460	ENOG4105C4M	(Ubiquinol oxidase) subunit I
D0812_09465	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
D0812_09480	ENOG4107YD3	Thioesterase
D0812_09485	ENOG4105E02	MotA TolQ exbB proton channel
D0812_09490	ENOG4105M8F	Biopolymer transport protein exbD tolR
D0812_09500	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
D0812_09505	ENOG4105KCK	Peptidoglycan-associated lipoprotein
D0812_09510	ENOG4105UFD	tol-pal system protein YbgF
D0812_09515	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
D0812_09525	ENOG4105Z6B	inner membrane protein yjfl
D0812_09535	ENOG4106032	Glutathionylspermidine synthase
D0812_09545	ENOG4105BZU	Histidine kinase
D0812_09550	ENOG4108RNS	Exports L-alanine (By similarity)
D0812_09575	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
D0812_09620	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
D0812_09625	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
D0812_09630	ENOG4105EUJ	GTP cyclohydrolase i
D0812_09635	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
D0812_09640	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D0812_09700	ENOG4105ENH	Sulfatase
D0812_09715	ENOG4105C5Y	PTS System
D0812_09720	ENOG4105CS2	ec 3.2.1.21
D0812_09725	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
D0812_09730	ENOG4105IJJ	transcriptional regulator, crp fnr family
D0812_09755	ENOG4107R73	Mate efflux family protein
D0812_09760	ENOG4105C3U	ABC transporter
D0812_09765	ENOG4108JQ7	(ABC) transporter
D0812_09770	ENOG4105DEF	Extracellular solute-binding protein, family 5
D0812_09785	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_09800	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
D0812_09805	ENOG4105BZS	acriflavin resistance protein
D0812_09815	ENOG4105JXH	GntR family transcriptional regulator
D0812_09850	ENOG4108IHU	transport system permease protein
D0812_09855	ENOG4108U1V	ABC transporter, permease
D0812_09860	ENOG4105E0A	ABC, transporter
D0812_09880	ENOG4107RJ1	sodium solute
D0812_09895	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
D0812_09905	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D0812_09910	ENOG41080XP	Cbs domain
D0812_09915	ENOG4107EJG	GntR family transcriptional regulator
D0812_09920	ENOG4105CHR	reductase
D0812_09925	ENOG4107EJG	GntR family transcriptional regulator
D0812_09950	ENOG4105D2H	Uronic isomerase
D0812_09955	ENOG4107RJ1	sodium solute
D0812_09970	ENOG4105M5J	Cupin 2, conserved barrel domain protein
D0812_09975	ENOG4105CHR	reductase
D0812_09995	ENOG4108PJD	permease
D0812_10030	ENOG4105KXC	Collagenase
D0812_10055	ENOG4107QUY	Guanine deaminase
D0812_10075	ENOG4105EY3	heparinase II III family protein
D0812_10080	ENOG4105EY3	heparinase II III family protein
D0812_10085	ENOG4105M5J	Cupin 2, conserved barrel domain protein
D0812_10090	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D0812_10095	ENOG4108UHU	Aldolase
D0812_10110	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
D0812_10120	ENOG4107R11	Transcriptional regulator
D0812_10130	ENOG4105DCF	alanine dehydrogenase
D0812_10135	ENOG4105EW9	transcriptional regulator AsnC family
D0812_10140	ENOG4105CNU	cell division protein FtsK
D0812_10145	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
D0812_10150	ENOG4105D1H	recombination factor protein RarA
D0812_10155	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
D0812_10165	ENOG4105KSC	Transcriptional regulator, TraR DksA family
D0812_10170	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
D0812_10175	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
D0812_10180	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D0812_10190	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
D0812_10200	ENOG4105D0M	Protease HtpX homolog
D0812_10210	ENOG4107FW0	short-chain dehydrogenase reductase
D0812_10225	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
D0812_10235	ENOG4105RHG	
D0812_10245	ENOG4107QTF	adenylosuccinate lyase
D0812_10250	ENOG41075W9	High frequency lysogenization protein HflD homolog
D0812_10255	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
D0812_10265	ENOG4107RE1	Inosine-guanosine kinase
D0812_10270	ENOG4108YX2	DNA-binding protein
D0812_10275	ENOG4107S6Z	Na H antiporter
D0812_10280	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
D0812_10285	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
D0812_10290	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D0812_10320	ENOG4105K5B	UPF0225 protein
D0812_10325	ENOG4105D58	Diguanylate phosphodiesterase
D0812_10330	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
D0812_10335	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D0812_10340	ENOG4105C8N	cysteinyl-tRNA synthetase
D0812_10345	ENOG4107104	thymidine kinase
D0812_10350	ENOG4105GFG	DUF218 domain
D0812_10375	ENOG4105TMB	Formate nitrite transporter
D0812_10395	ENOG4108J2R	molybdopterin oxidoreductase
D0812_10410	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
D0812_10420	ENOG4108JQ2	peptide transport system atp-binding protein
D0812_10425	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
D0812_10430	ENOG4108EU3	peptide transport system, permease
D0812_10435	ENOG4108I5W	peptide transport system, permease protein
D0812_10440	ENOG4108J59	Extracellular solute-binding protein, family 5
D0812_10445	ENOG4105E51	psp operon transcriptional activator
D0812_10450	ENOG41087YS	Phage shock protein A
D0812_10455	ENOG4105YYT	phage shock protein B
D0812_10460	ENOG4105FM1	phage shock protein C
D0812_10480	ENOG4108R3E	Dna-3-methyladenine glycosylase i
D0812_10490	ENOG4107IFA	Lipase (EC 3.1.1.3)
D0812_10495	ENOG4105C28	cystathionine
D0812_10505	ENOG4105C8J	)-transporter
D0812_10515	ENOG4108W1A	pseudouridine synthase
D0812_10530	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
D0812_10535	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
D0812_10540	ENOG4108JUA	Transcriptional regulator
D0812_10545	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
D0812_10550	ENOG4108VGW	abc transporter atp-binding protein
D0812_10555	ENOG4105CXZ	ABC transporter, permease
D0812_10560	ENOG4105VNH	ABC transporter solute-binding protein
D0812_10565	ENOG4108RSN	SNARE associated Golgi
D0812_10575	ENOG4105BZ8	glutamate synthase
D0812_10585	ENOG4106AFQ	Histidine kinase
D0812_10590	ENOG4108ZXC	Two component transcriptional regulator, luxr family
D0812_10600	ENOG4105CHH	sulfate transporter
D0812_10610	ENOG4105XZD	Fe-S protein
D0812_10625	ENOG4105CGH	5'-nucleotidase
D0812_10640	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
D0812_10660	ENOG4105EB3	Histidine kinase
D0812_10665	ENOG4105ETX	regulatoR
D0812_10675	ENOG4108KHP	Diguanylate cyclase
D0812_10680	ENOG4105CFI	type iii restriction protein res subunit
D0812_10685	ENOG4105I08	Pseudouridine synthase
D0812_10690	ENOG4105C2C	drug resistance transporter, Bcr CflA
D0812_10700	ENOG4108NRW	Phospholipase, patatin family
D0812_10705	ENOG4105CGD	Nad-dependent epimerase dehydratase
D0812_10710	ENOG4107QI1	Mate efflux family protein
D0812_10715	ENOG4108I0Y	(ABC) transporter
D0812_10730	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D0812_10735	ENOG41067SE	Tetr family transcriptional regulator
D0812_10740	ENOG4107QPN	acyl-Coa dehydrogenase
D0812_10745	ENOG4105RKW	reductase (By
D0812_10750	ENOG4105D0C	transport protein
D0812_10755	ENOG41090BQ	Glutaredoxin
D0812_10765	ENOG4106KNT	transcriptional regulator
D0812_10770	ENOG4105DY8	decarboxylase
D0812_10780	ENOG4105DWU	Membrane
D0812_10810	ENOG4105BZU	Histidine kinase
D0812_10820	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
D0812_10830	ENOG4105BZU	Histidine kinase
D0812_10860	ENOG4105BZU	Histidine kinase
D0812_10865	ENOG4105W8I	Transcriptional regulator
D0812_10870	ENOG4105BZC	d-serine deaminase
D0812_10875	ENOG4108JJ8	(ABC) transporter
D0812_10880	ENOG4108JJ9	ABC, transporter
D0812_10885	ENOG4105C3M	thioredoxin reductase
D0812_10905	ENOG4105BZU	Histidine kinase
D0812_10910	ENOG4105C8P	)-transporter
D0812_10915	ENOG4107GZ4	SanA protein
D0812_10920	ENOG4107R1I	NAD-dependent malic enzyme
D0812_10925	ENOG4105CQ7	ATP-dependent helicase
D0812_10930	ENOG4105HDD	phospholipase
D0812_10945	ENOG4105C8V	SAICAR synthetase
D0812_10975	ENOG4105CDV	Ompa motb domain protein
D0812_10990	ENOG4105CQB	FAD linked oxidase domain protein
D0812_11005	ENOG4105C84	Histidine ammonia-lyase
D0812_11010	ENOG4105CGP	Urocanate hydratase
D0812_11015	ENOG41088SP	formiminoglutamate hydrolase
D0812_11020	ENOG4105CI2	imidazolone-5-propionate hydrolase
D0812_11025	ENOG4105CZE	histidine utilization repressor
D0812_11040	ENOG4105C22	threonyL-tRNA synthetase
D0812_11045	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
D0812_11050	ENOG41082NX	50s ribosomal protein l35
D0812_11055	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
D0812_11070	ENOG4105KME	endoribonuclease L-psp
D0812_11075	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
D0812_11080	ENOG4105K8R	UPF0145 protein
D0812_11110	ENOG4108KHP	Diguanylate cyclase
D0812_11115	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
D0812_11120	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
D0812_11130	ENOG4107R3K	hydrolase
D0812_11135	ENOG4105D7K	pfkb domain protein
D0812_11140	ENOG4105WBN	Transcriptional regulator (LacI family
D0812_11150	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D0812_11160	ENOG4105FQ6	thiopurine methyltransferase
D0812_11165	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
D0812_11175	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
D0812_11180	ENOG41067MG	lrgb family
D0812_11185	ENOG4105VAW	lrga family
D0812_11190	ENOG4105CJB	Exodeoxyribonuclease I
D0812_11200	ENOG4108ETY	sodium dicarboxylate symporter
D0812_11205	ENOG4105K4T	epimerase
D0812_11210	ENOG4107XWI	flavin reductase domain protein, FMN-binding
D0812_11215	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
D0812_11220	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
D0812_11230	ENOG4108TGR	phosphatase
D0812_11240	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
D0812_11245	ENOG4108IU2	vtamin B12-transporter permease
D0812_11250	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
D0812_11275	ENOG4105F04	LysR family Transcriptional regulator
D0812_11300	ENOG4108VAU	general secretion pathway protein G
D0812_11305	ENOG4108VKG	metal-dependent hydrolase
D0812_11310	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
D0812_11315	ENOG4105BZU	Histidine kinase
D0812_11325	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
D0812_11335	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
D0812_11340	ENOG4105F1J	Homogentisate 1,2-dioxygenase
D0812_11350	ENOG4108RXX	maleylacetoacetate isomerase
D0812_11390	ENOG4106YYS	transcriptional regulatory protein
D0812_11395	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
D0812_11400	ENOG4105D9Q	decarboxylase (Beta subunit)
D0812_11405	ENOG4107QSA	Oxaloacetate decarboxylase
D0812_11420	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
D0812_11425	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
D0812_11430	ENOG4105CI0	Citrate lyase
D0812_11435	ENOG4105CHY	citrate lyase, alpha
D0812_11440	ENOG4105YGP	holo-ACP synthase CitX
D0812_11445	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
D0812_11460	ENOG4108WQH	regulatoR
D0812_11475	ENOG4107EDW	L-fucose operon activator
D0812_11480	ENOG4105EDR	glucose galactose transporter
D0812_11490	ENOG4105CMG	Carbohydrate kinase
D0812_11495	ENOG4105NWF	RbsD or FucU transport
D0812_11500	ENOG4107W7X	Aldolase
D0812_11505	ENOG4105C0A	alcohol dehydrogenase
D0812_11520	ENOG4105Q9Y	Universal stress protein
D0812_11525	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D0812_11530	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D0812_11590	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D0812_11605	ENOG4107QHE	Choloylglycine hydrolase
D0812_11610	ENOG4108MA4	Peptidase M66
D0812_11620	ENOG4105CUY	Mechanosensitive ion channel
D0812_11625	ENOG4108YK4	Acid-resistance membrane protein
D0812_11630	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D0812_11645	ENOG4108ZT1	Transcriptional regulator
D0812_11685	ENOG4105BZU	Histidine kinase
D0812_11690	ENOG4108UW5	maltose o-acetyltransferase
D0812_11710	ENOG4105BZU	Histidine kinase
D0812_11715	ENOG4105BZU	Histidine kinase
D0812_11740	ENOG4105F88	accessory colonization factor AcfD
D0812_11755	ENOG4105CND	Glycosyl transferase, family 2
D0812_11760	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
D0812_11800	ENOG4107TAE	Glycosyl transferase (Group 1
D0812_11810	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_11825	ENOG4107V1M	polysaccharide export protein
D0812_11830	ENOG4107QKZ	Ompa motb domain protein
D0812_11835	ENOG41082AN	stage II sporulation protein
D0812_11850	ENOG4107QI1	Mate efflux family protein
D0812_11855	ENOG4108R6K	riboflavin synthase, subunit alpha
D0812_11865	ENOG4105FGM	Fructosamine kinase
D0812_11870	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D0812_11875	ENOG4105BZU	Histidine kinase
D0812_11885	ENOG4107TT5	NLP P60 protein
D0812_11890	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_11940	ENOG4106IUH	DTW domain containing protein
D0812_11945	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
D0812_11960	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D0812_11965	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
D0812_11970	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D0812_11975	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
D0812_11985	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_11990	ENOG4105BZU	Histidine kinase
D0812_12010	ENOG4105C5H	ABC transporter
D0812_12015	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
D0812_12035	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
D0812_12045	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D0812_12050	ENOG4105QAX	Iron-sulfur
D0812_12065	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
D0812_12070	ENOG4107RUE	extracellular solute-binding protein family 1
D0812_12075	ENOG4107RUE	extracellular solute-binding protein family 1
D0812_12080	ENOG4105D38	putrescine abc transporter
D0812_12085	ENOG4105F38	ABC transporter, permease
D0812_12090	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D0812_12110	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
D0812_12115	ENOG4105Q9Y	Universal stress protein
D0812_12120	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
D0812_12135	ENOG4105C59	p-type ATPase
D0812_12145	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
D0812_12160	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
D0812_12175	ENOG4105BZU	Histidine kinase
D0812_12200	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
D0812_12205	ENOG4105DAN	ATP-dependent protease
D0812_12210	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
D0812_12225	ENOG4105C5H	ABC transporter
D0812_12235	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
D0812_12240	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
D0812_12245	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D0812_12250	ENOG4105C7I	Dehydrogenase
D0812_12260	ENOG4105CD8	aminopeptidase N
D0812_12270	ENOG4105CN1	protease
D0812_12275	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
D0812_12280	ENOG4108ZGC	gaf domain protein
D0812_12285	ENOG4105BZ1	(ABC) transporter
D0812_12290	ENOG4105H2K	paraquat-inducible protein a
D0812_12295	ENOG4105DY2	Paraquat-inducible protein b
D0812_12300	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
D0812_12320	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
D0812_12325	ENOG4108VPT	UPF0234 protein
D0812_12340	ENOG4107QXX	ABC transporter
D0812_12345	ENOG4105EZ7	amino acid ABC transporter
D0812_12350	ENOG4105DRP	amino acid AbC transporter
D0812_12355	ENOG4105CDA	abc transporter atp-binding protein
D0812_12360	ENOG4108MN8	Membrane
D0812_12370	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
D0812_12375	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
D0812_12380	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_12385	ENOG4105DR4	Methyltransferase
D0812_12415	ENOG4105CDV	Ompa motb domain protein
D0812_12425	ENOG4105BZU	Histidine kinase
D0812_12430	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
D0812_12435	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
D0812_12440	ENOG410667J	hydrolase
D0812_12450	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
D0812_12460	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D0812_12465	ENOG4105C7F	AcnD-accessory protein PrpF
D0812_12470	ENOG4108I0Z	Aconitate hydratase
D0812_12475	ENOG4105BZN	citrate synthase
D0812_12480	ENOG4105CR4	methylisocitrate lyase
D0812_12495	ENOG4105CS6	Rhs element vgr protein
D0812_12550	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D0812_12590	ENOG4108ESY	Metal dependent phosphohydrolase
D0812_12595	ENOG4108ESY	Metal dependent phosphohydrolase
D0812_12630	ENOG4105EJ9	Membrane
D0812_12635	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_12645	ENOG4105BZS	acriflavin resistance protein
D0812_12655	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D0812_12660	ENOG4105C26	Dehydrogenase
D0812_12665	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
D0812_12695	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
D0812_12700	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
D0812_12705	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
D0812_12710	ENOG4108V9W	transcriptional regulatory protein
D0812_12715	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
D0812_12720	ENOG4105C87	Aminotransferase class I and II
D0812_12840	ENOG4105K5B	UPF0225 protein
D0812_12865	ENOG4106V8H	Nucleoid-associated protein
D0812_12895	ENOG4108WTW	DNA transposition protein
D0812_12905	ENOG4105HVQ	Regulatory factor of maltose metabolism
D0812_12920	ENOG4105EQ2	LysR family Transcriptional regulator
D0812_12925	ENOG4105CVE	Lytic murein transglycosylase
D0812_12930	ENOG4105VNG	YcgL domain-containing protein
D0812_12935	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
D0812_12940	ENOG4107QMS	site-determining protein
D0812_12945	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
D0812_12950	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
D0812_12955	ENOG4105CEY	Amp-dependent synthetase and ligase
D0812_12960	ENOG410832A	alpha/beta hydrolase fold
D0812_12965	ENOG4105R8X	Outer membrane lipoprotein Slp
D0812_12975	ENOG41072GX	Peptidase M22 Glycoprotease
D0812_12980	ENOG4105DVT	helicase
D0812_12985	ENOG4105CIY	formyltetrahydrofolate deformylase
D0812_12990	ENOG4106ZCM	YecM protein
D0812_13000	ENOG4105C75	arginyL-tRNA synthetase
D0812_13020	ENOG4105XFK	Ferrous iron transport protein A
D0812_13025	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
D0812_13030	ENOG4105NXV	High-affinity zinc uptake system protein
D0812_13035	ENOG4105FDK	ABC transporter
D0812_13040	ENOG4105FAV	ABC, transporter
D0812_13045	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
D0812_13050	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
D0812_13055	ENOG4105C7S	Dehydrogenase
D0812_13060	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
D0812_13065	ENOG4105E33	succinate dehydrogenase
D0812_13070	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
D0812_13075	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
D0812_13080	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
D0812_13085	ENOG4105BZN	citrate synthase
D0812_13090	ENOG4107QNR	UPF0135 protein
D0812_13100	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
D0812_13105	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
D0812_13110	ENOG4105EV9	Alpha Beta Hydrolase
D0812_13120	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
D0812_13130	ENOG41090R7	Ferric uptake
D0812_13135	ENOG4105X0D	Fimbrial protein
D0812_13140	ENOG4105CX6	glutaminyL-tRNA synthetase
D0812_13145	ENOG4105CI1	PTS System
D0812_13155	ENOG4105CE4	GlcNAc 6-P deacetylase
D0812_13160	ENOG4105E2R	ROK family
D0812_13165	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
D0812_13170	ENOG4105CAQ	asparagine synthetase
D0812_13175	ENOG4105MDZ	Transcriptional activator rfaH
D0812_13180	ENOG4105DUX	Transporter
D0812_13185	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
D0812_13190	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D0812_13195	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
D0812_13200	ENOG4108DQ1	activator toxR
D0812_13220	ENOG4108RE9	Phosphodiesterase
D0812_13250	ENOG4105ECP	epimerase
D0812_13255	ENOG4105E1F	short-chain dehydrogenase reductase
D0812_13265	ENOG4107QR8	Thioredoxin
D0812_13275	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
D0812_13280	ENOG4107EEX	Cellulose synthase regulator protein
D0812_13285	ENOG4107QZ7	Cellulose synthase catalytic subunit
D0812_13305	ENOG4105D1V	cellulose synthase operon protein YhjU
D0812_13310	ENOG4107QX8	SPFH domain, Band 7 family protein
D0812_13340	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
D0812_13350	ENOG4105EXN	Sulfate transport protein CysZ
D0812_13355	ENOG4105C6T	cysteine synthase
D0812_13365	ENOG4105KZ7	phosphocarrier protein hpr
D0812_13370	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
D0812_13375	ENOG4105C5Y	PTS System
D0812_13385	ENOG4105I03	Flagellin
D0812_13390	ENOG4105I03	Flagellin
D0812_13405	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
D0812_13410	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D0812_13415	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D0812_13420	ENOG4105CGA	flagellar basal-body rod protein FlgG
D0812_13425	ENOG4108KPB	Flagellar basal-body rod protein FlgF
D0812_13430	ENOG4105BZE	flagellar hook protein, FlgE
D0812_13435	ENOG4105W00	Flagellar hook capping protein
D0812_13440	ENOG4108ZC9	flagellar basal-body rod protein flgc
D0812_13445	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
D0812_13450	ENOG4105BZU	Histidine kinase
D0812_13455	ENOG4107R88	Chemotaxis protein (CheV)
D0812_13500	ENOG4105UYK	outer membrane protein a
D0812_13505	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
D0812_13515	ENOG41081QG	Porin Gram-negative type
D0812_13525	ENOG4105C59	p-type ATPase
D0812_13540	ENOG4105E2D	ec 3.2.1.52
D0812_13560	ENOG4108DG9	Smr protein MutS2
D0812_13565	ENOG4105FE9	pseudouridine synthase
D0812_13570	ENOG4108Z66	YbaK ebsC protein
D0812_13575	ENOG4105CGH	5'-nucleotidase
D0812_13580	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D0812_13585	ENOG41063JG	Transcriptional regulator
D0812_13590	ENOG4108YY7	Invasion gene expression up-regulator SirB
D0812_13595	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
D0812_13600	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D0812_13605	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
D0812_13615	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
D0812_13620	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D0812_13625	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
D0812_13630	ENOG4105C3G	gtp-binding protein
D0812_13740	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
D0812_13750	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D0812_13755	ENOG4105C9A	Phoh family
D0812_13760	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
D0812_13765	ENOG4108JU5	Magnesium and cobalt efflux protein
D0812_13770	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
D0812_13775	ENOG4107PAI	alpha helical protein
D0812_13780	ENOG4105C8T	Leucyl-tRNA synthetase
D0812_13785	ENOG4108U2H	Rare lipoprotein B
D0812_13790	ENOG4105DJF	DNA polymerase III, delta' subunit
D0812_13795	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
D0812_13800	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
D0812_13805	ENOG4105CJN	penicillin-binding protein
D0812_13810	ENOG4105CNI	cell division protein FtsW
D0812_13815	ENOG4105K6T	rare lipoprotein A
D0812_13820	ENOG4105DZ1	carboxypeptidase
D0812_13825	ENOG4108Z43	UPF0250 protein
D0812_13830	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D0812_13835	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
D0812_13840	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D0812_13845	ENOG4108JYZ	YitT family
D0812_13860	ENOG4105CG3	alpha amylase, catalytic region
D0812_13865	ENOG4105C5Y	PTS System
D0812_13870	ENOG4105D4X	repressor
D0812_13875	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
D0812_13880	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
D0812_13885	ENOG4108UMI	ABC transporter, permease
D0812_13890	ENOG4105D01	(LipO)protein
D0812_13900	ENOG4105CGH	5'-nucleotidase
D0812_13905	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
D0812_13910	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
D0812_13915	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
D0812_13925	ENOG4105BZU	Histidine kinase
D0812_13930	ENOG4105EWT	decarboxylase family
D0812_13935	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
D0812_13940	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
D0812_13945	ENOG4105M08	Membrane
D0812_13955	ENOG4105ETT	transcriptional Regulator, LysR family
D0812_13960	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
D0812_13965	ENOG4106VK6	Flagellar motor protein
D0812_13965	ENOG4106VK6	Flagellar motor protein
D0812_13970	ENOG4105E14	MotA TolQ exbB proton channel
D0812_13975	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D0812_13980	ENOG4105CTB	Polyprenyl synthetase
D0812_13985	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D0812_13990	ENOG4108ZAI	phosphatidylglycerophosphatase a
D0812_13995	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
D0812_14000	ENOG4107YIM	Involved in the transcription termination process (By similarity)
D0812_14005	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
D0812_14020	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D0812_14025	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
D0812_14030	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
D0812_14035	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D0812_14040	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
D0812_14045	ENOG4108DJV	Fermentation respiration switch protein
D0812_14050	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
D0812_14055	ENOG4105C7N	Xanthine uracil vitamin C permease
D0812_14060	ENOG4105CIN	aminoacyl-histidine dipeptidase
D0812_14095	ENOG4108ETH	Formylglycinamide ribotide synthetase
D0812_14100	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
D0812_14110	ENOG4108Z6B	deaminase
D0812_14120	ENOG4105CFC	Transporter
D0812_14155	ENOG4105CFG	Acts as a chaperone (By similarity)
D0812_14170	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D0812_14175	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
D0812_14185	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
D0812_14190	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
D0812_14195	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D0812_14205	ENOG4105VDB	UPF0125 protein
D0812_14210	ENOG4108Z1B	Cyclase dehydrase
D0812_14215	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
D0812_14225	ENOG4105ETT	transcriptional Regulator, LysR family
D0812_14230	ENOG410613R	integral membrane protein, YccS YhfK family
D0812_14250	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
D0812_14255	ENOG4108IQK	o-acetylhomoserine
D0812_14260	ENOG4105D64	Mechanosensitive ion channel
D0812_14275	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
D0812_14280	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
D0812_14285	ENOG4105BZG	amino acid carrier protein
D0812_14290	ENOG4106HK8	GPR1 FUN34 yaaH family protein
D0812_14300	ENOG4107S6Z	Na H antiporter
D0812_14305	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D0812_14310	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D0812_14315	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D0812_14325	ENOG410620I	Diguanylate cyclase
D0812_14335	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
D0812_14340	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D0812_14345	ENOG4105N21	Membrane
D0812_14350	ENOG4105CUT	histidyl-tRNA synthetase
D0812_14355	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
D0812_14365	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
D0812_14370	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
D0812_14375	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D0812_14380	ENOG4105WVQ	Fe-S assembly protein IscX
D0812_14385	ENOG4108ZIT	Ferredoxin, 2FE-2S
D0812_14390	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
D0812_14395	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
D0812_14400	ENOG4108Z4V	iron-sulfur cluster assembly
D0812_14405	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
D0812_14410	ENOG4105C3J	Cysteine desulfurase
D0812_14415	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
D0812_14420	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
D0812_14430	ENOG4105ECY	inositol monophosphatase
D0812_14435	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D0812_14440	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D0812_14445	ENOG4105VIE	preprotein translocase, subunit YajC
D0812_14450	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
D0812_14455	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
D0812_14470	ENOG4105W87	Cbs domain
D0812_14475	ENOG4108I9X	Isocitrate lyase
D0812_14480	ENOG4107QP3	malate synthase g
D0812_14485	ENOG4105C5Q	Transcriptional regulator
D0812_14490	ENOG4105D3R	alkyl hydroperoxide reductase
D0812_14495	ENOG4106N3A	copper homeostasis protein cutc
D0812_14500	ENOG4105CSR	polyphosphate kinase 2
D0812_14525	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D0812_14530	ENOG4105E2Z	phosphate ABC transporter (Permease
D0812_14535	ENOG4105C8U	phosphate abc transporter
D0812_14540	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
D0812_14545	ENOG4105C9X	ppx gppa phosphatase
D0812_14555	ENOG4105BZU	Histidine kinase
D0812_14560	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D0812_14565	ENOG4105DH7	May be involved in recombination (By similarity)
D0812_14570	ENOG4105CFP	Peptidase U32
D0812_14575	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
D0812_14635	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D0812_14640	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
D0812_14645	ENOG4105C34	Pseudouridine synthase
D0812_14650	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0812_14655	ENOG4105E4C	Lytic transglycosylase catalytic
D0812_14660	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
D0812_14670	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D0812_14675	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
D0812_14680	ENOG4107SC1	transglycosylase
D0812_14685	ENOG4105C5H	ABC transporter
D0812_14695	ENOG4105DR5	peptidase
D0812_14700	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
D0812_14705	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
D0812_14710	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
D0812_14715	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
D0812_14720	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D0812_14740	ENOG4108HRK	Histidine kinase
D0812_14745	ENOG4108NEV	two component transcriptional regulator, LytTR family
D0812_14750	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
D0812_14755	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
D0812_14760	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D0812_14765	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
D0812_14770	ENOG4105DTN	riboflavin biosynthesis protein ribF
D0812_14775	ENOG4105CJR	Integral membrane protein (MviN
D0812_14780	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
D0812_14785	ENOG41080HT	Transcriptional regulator, arsr family
D0812_14790	ENOG41063Z6	transcriptional regulator, lysR family
D0812_14805	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
D0812_14810	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
D0812_14815	ENOG4105HF0	Membrane
D0812_14820	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
D0812_14825	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
D0812_14830	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
D0812_14840	ENOG4105CPC	Aldo Keto reductase
D0812_14850	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_14855	ENOG4105CRK	lysyL-tRNA synthetase
D0812_14865	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
D0812_14870	ENOG4105T95	Thiol disulfide interChange protein
D0812_14875	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D0812_14880	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
D0812_14885	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
D0812_14890	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
D0812_14895	ENOG4105C1J	atp-dependent rna helicase
D0812_14905	ENOG4105D1Q	UPF0246 protein
D0812_14910	ENOG4105BZG	amino acid carrier protein
D0812_14925	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
D0812_14935	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
D0812_14940	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
D0812_14950	ENOG4105D98	threonine synthase
D0812_14955	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
D0812_14970	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
D0812_14985	ENOG41065U4	response regulator
D0812_14995	ENOG4105BZU	Histidine kinase
D0812_15005	ENOG4105N5T	Radical SAM Protein
D0812_15020	ENOG4105CBC	glutamate synthase
D0812_15025	ENOG4105BZ8	glutamate synthase
D0812_15035	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
D0812_15045	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
D0812_15050	ENOG4105EN6	Membrane
D0812_15055	ENOG4105VP0	transcriptional regulator, lysR family
D0812_15060	ENOG4105EJ9	Membrane
D0812_15075	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
D0812_15080	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
D0812_15085	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
D0812_15090	ENOG4105M6F	mutator MutT protein
D0812_15095	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D0812_15105	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D0812_15110	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
D0812_15115	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
D0812_15120	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
D0812_15125	ENOG4105DFU	Cell wall formation (By similarity)
D0812_15130	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D0812_15140	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
D0812_15145	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
D0812_15150	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
D0812_15155	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
D0812_15160	ENOG4105CJN	penicillin-binding protein
D0812_15165	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
D0812_15170	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
D0812_15185	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
D0812_15195	ENOG41082RQ	UPF0102 protein
D0812_15200	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
D0812_15205	ENOG4105W4M	Transport-associated protein
D0812_15210	ENOG4105KB2	stringent starvation protein b
D0812_15215	ENOG4107MKT	Stringent starvation protein a
D0812_15220	ENOG4105EIX	cytochrome c1
D0812_15225	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D0812_15230	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D0812_15235	ENOG4108UJD	30S ribosomal protein S9
D0812_15240	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
D0812_15250	ENOG4105D6Z	AFG1 family ATPase
D0812_15260	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
D0812_15265	ENOG4105C0H	protease
D0812_15270	ENOG4105C0H	protease
D0812_15275	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D0812_15280	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D0812_15285	ENOG4105IPS	esterase
D0812_15290	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
D0812_15295	ENOG4108SX3	cytoplasmic protein
D0812_15300	ENOG41087AY	ADP-Ribose pyrophosphatase
D0812_15305	ENOG4105DFG	type I secretion outer membrane protein
D0812_15310	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
D0812_15315	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
D0812_15320	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_15330	ENOG4105I7R	Adenylate cyclase
D0812_15335	ENOG4107IX6	phosphate transport regulator
D0812_15340	ENOG4105CJ3	phosphate transporter
D0812_15345	ENOG4106MWK	domain protein
D0812_15350	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D0812_15370	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
D0812_15375	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
D0812_15380	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D0812_15385	ENOG4107ZVW	dihydroneopterin aldolase
D0812_15390	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
D0812_15395	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
D0812_15400	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D0812_15405	ENOG4105VCC	30S ribosomal protein S21
D0812_15410	ENOG4105KTH	gatB Yqey
D0812_15415	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
D0812_15420	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D0812_15450	ENOG4105CTS	PTS system mannitol-specific
D0812_15455	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
D0812_15460	ENOG4105E61	Mannitol repressor protein
D0812_15465	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
D0812_15470	ENOG4105GR3	Histidine kinase
D0812_15490	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
D0812_15495	ENOG410804X	Transcriptional regulator
D0812_15505	ENOG4105CA9	Pyruvate kinase
D0812_15515	ENOG4105BZU	Histidine kinase
D0812_15520	ENOG4108ZP8	Acetolactate synthase small subunit
D0812_15525	ENOG4105C7K	acetolactate synthase
D0812_15530	ENOG4108IQE	Amp-dependent synthetase and ligase
D0812_15535	ENOG41064T2	transcriptional regulator, lysR family
D0812_15565	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
D0812_15570	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D0812_15575	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D0812_15580	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D0812_15590	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
D0812_15595	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
D0812_15600	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
D0812_15605	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
D0812_15610	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D0812_15615	ENOG4105NWN	ApaG protein
D0812_15620	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
D0812_15625	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
D0812_15630	ENOG4107XM3	UPF0442 protein
D0812_15635	ENOG4105DWK	Membrane
D0812_15640	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D0812_15645	ENOG4105K46	50S ribosomal protein l27
D0812_15650	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
D0812_15655	ENOG4105EAH	synthase
D0812_15665	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
D0812_15670	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
D0812_15695	ENOG4107T0D	ABC, transporter
D0812_15700	ENOG4106SMU	thiamine transporter membrane protein
D0812_15705	ENOG4105DP9	ABC transporter
D0812_15710	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
D0812_15715	ENOG4105DFU	Cell wall formation (By similarity)
D0812_15720	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D0812_15725	ENOG4105F0N	pyrophosphate phospho-hydrolase
D0812_15740	ENOG41066HZ	AIG2-like family
D0812_15750	ENOG4105CFU	surface antigen
D0812_15755	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D0812_15785	ENOG4105C7H	Helicase, RecD TraA family
D0812_15815	ENOG4108UUE	Transcriptional regulator
D0812_15830	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D0812_15850	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
D0812_15860	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
D0812_15865	ENOG4105C11	sulfate adenylyltransferase), subunit 2
D0812_15870	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D0812_15875	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
D0812_15890	ENOG4105C1J	atp-dependent rna helicase
D0812_15895	ENOG4107YB6	acetyltransferase, (GNAT) family
D0812_15910	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D0812_15920	ENOG4108ZT0	50S ribosomal protein l17
D0812_15925	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D0812_15930	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
D0812_15935	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
D0812_15940	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D0812_15950	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
D0812_15955	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
D0812_15960	ENOG4105VPB	50S ribosomal protein L30
D0812_15965	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
D0812_15975	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
D0812_15980	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
D0812_15985	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
D0812_15990	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D0812_15995	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
D0812_16000	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
D0812_16005	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
D0812_16010	ENOG41083MP	50s ribosomal protein l29
D0812_16015	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
D0812_16020	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
D0812_16025	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
D0812_16030	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
D0812_16035	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D0812_16040	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
D0812_16045	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
D0812_16050	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
D0812_16055	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
D0812_16060	ENOG4105VFB	Binds the 23S rRNA (By similarity)
D0812_16070	ENOG4105C25	Primosomal protein n'
D0812_16075	ENOG4105ETE	Transcriptional regulator (LacI family
D0812_16085	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
D0812_16090	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
D0812_16095	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
D0812_16100	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
D0812_16105	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
D0812_16110	ENOG4105CBT	Fructose-1,6-bisphosphatase
D0812_16140	ENOG4105CP7	Triose-phosphate isomerase
D0812_16155	ENOG4105ESV	Glycosyl transferase, family 4
D0812_16160	ENOG4105C2X	Arabinose 5-phosphate isomerase
D0812_16165	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
D0812_16170	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D0812_16205	ENOG4108UT6	Transferase hexapeptide repeat containing protein
D0812_16210	ENOG4105CHR	reductase
D0812_16235	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
D0812_16245	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
D0812_16250	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
D0812_16260	ENOG4105DAY	polysaccharide export protein
D0812_16285	ENOG4105E3R	(LipO)protein
D0812_16290	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
D0812_16295	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
D0812_16305	ENOG4105XA0	heptosyltransferase ii
D0812_16310	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
D0812_16325	ENOG4105CAQ	asparagine synthetase
D0812_16330	ENOG4105D3Q	Sugar transferase
D0812_16350	ENOG4105F0R	Cytidylyltransferase
D0812_16355	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
D0812_16360	ENOG41080IJ	Diacylglycerol kinase
D0812_16365	ENOG4105DKP	glycosyl transferase, family 9
D0812_16370	ENOG4106WTF	Glycosyl transferase, family 2
D0812_16380	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
D0812_16385	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
D0812_16390	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
D0812_16405	ENOG4105KDC	50s ribosomal protein l28
D0812_16410	ENOG4105W5Q	DNA repair protein (RadC
D0812_16415	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_16425	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
D0812_16430	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
D0812_16435	ENOG4105D1S	lipid A biosynthesis
D0812_16440	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
D0812_16445	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
D0812_16450	ENOG4105DSJ	YicC domain protein
D0812_16455	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
D0812_16465	ENOG4105DWP	Membrane
D0812_16480	ENOG4108JQ7	(ABC) transporter
D0812_16490	ENOG4107QRA	Extracellular solute-binding protein, family 5
D0812_16495	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
D0812_16500	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
D0812_16530	ENOG4109015	Biopolymer transport protein exbD tolR
D0812_16545	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
D0812_16550	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
D0812_16555	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D0812_16560	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
D0812_16565	ENOG4105CB5	ATP-dependent DNA helicase recG
D0812_16575	ENOG4105C2W	permease
D0812_16580	ENOG4105E0F	Histidine kinase
D0812_16585	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D0812_16590	ENOG4108RRZ	Transcription elongation factor GreB
D0812_16600	ENOG4105BZM	domain protein
D0812_16610	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
D0812_16615	ENOG4105MJ2	Competence protein
D0812_16620	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
D0812_16625	ENOG4107RK2	ADP-ribose diphosphatase NudE
D0812_16630	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
D0812_16635	ENOG4105PIC	general secretion pathway protein N
D0812_16640	ENOG4105U1E	general secretion pathway protein M
D0812_16645	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
D0812_16650	ENOG4108RTD	type II secretion system protein K
D0812_16655	ENOG4108WWZ	General secretion pathway protein J
D0812_16660	ENOG4105X5Z	General secretion pathway protein I
D0812_16665	ENOG4105VWV	general secretion pathway protein h
D0812_16670	ENOG4108VAU	general secretion pathway protein G
D0812_16675	ENOG4105D7Q	type ii secretion system
D0812_16680	ENOG4107QHF	type ii secretion system protein e
D0812_16690	ENOG4108XKW	General secretion pathway protein C
D0812_16695	ENOG4105VEJ	Heat shock protein
D0812_16700	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
D0812_16705	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
D0812_16715	ENOG4105SUU	thioesterase domain
D0812_16720	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
D0812_16725	ENOG4107S2Z	UPF0761 membrane protein
D0812_16750	ENOG4105C5F	glutamine synthetase
D0812_16760	ENOG4105CUX	Signal transduction histidine kinase
D0812_16765	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_16770	ENOG4105BZU	Histidine kinase
D0812_16775	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
D0812_16780	ENOG4105D4P	Coproporphyrinogen iii oxidase
D0812_16785	ENOG4105XCT	Protein of unknown function (DUF2489)
D0812_16790	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
D0812_16810	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
D0812_16820	ENOG4105C2M	dna polymerase I
D0812_16835	ENOG4105D52	delta-aminolevulinic acid dehydratase
D0812_16840	ENOG4105F8V	Hydrolase, tatD family
D0812_16845	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
D0812_16850	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
D0812_16855	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D0812_16860	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
D0812_16865	ENOG4105JC1	sterol-binding domain protein
D0812_16875	ENOG4105CGY	Dna recombination protein
D0812_16885	ENOG4105BZU	Histidine kinase
D0812_16910	ENOG4105CVR	type I restriction-modification system
D0812_16985	ENOG4105CBX	hi0933 family
D0812_17015	ENOG4108V6B	universal stress protein B
D0812_17020	ENOG41090A1	ferritin
D0812_17025	ENOG4108M6U	Universal stress protein A
D0812_17030	ENOG4105EMK	carboxylate amino acid amine transporter
D0812_17040	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
D0812_17045	ENOG4105BZU	Histidine kinase
D0812_17050	ENOG4108VVK	transcriptional Regulator, AsnC
D0812_17055	ENOG4105DGW	oligopeptidase A
D0812_17065	ENOG4105D6S	protein involved in catabolism of external DNA
D0812_17075	ENOG4105DC8	reductase
D0812_17105	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
D0812_17120	ENOG4105CS6	Rhs element vgr protein
D0812_17150	ENOG4108UHU	Aldolase
D0812_17155	ENOG4105C6Z	Gluconate
D0812_17160	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
D0812_17165	ENOG4105C01	Dihydroxy-acid dehydratase
D0812_17175	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
D0812_17180	ENOG41064T2	transcriptional regulator, lysR family
D0812_17185	ENOG4105DIQ	Transcriptional regulator
D0812_17220	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D0812_17225	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D0812_17235	ENOG4108JQ6	ABC transporter
D0812_17245	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D0812_17275	ENOG4105MPD	Cytochrome
D0812_17280	ENOG4105C4R	Atp-dependent dna helicase
D0812_17285	ENOG4107Z3H	Transcriptional regulator, TetR family
D0812_17290	ENOG410624X	efflux transporter, rnd family, mfp subunit
D0812_17295	ENOG4105BZS	acriflavin resistance protein
D0812_17305	ENOG4105W0Z	cytoplasmic protein
D0812_17310	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D0812_17315	ENOG4105EMY	transcriptional regulator
D0812_17360	ENOG4108Z0R	Transferase
D0812_17365	ENOG4105SG3	Protein of unknown function (DUF1488)
D0812_17370	ENOG4105E2X	shikimate dehydrogenase
D0812_17375	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
D0812_17380	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D0812_17385	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
D0812_17390	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
D0812_17395	ENOG4108WI1	Dna topoisomerase
D0812_17400	ENOG4108RPN	Protein smg homolog
D0812_17405	ENOG4105C79	DNA protecting protein DprA
D0812_17420	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
D0812_17425	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
D0812_17430	ENOG4105C1A	potassium transporter peripheral membrane
D0812_17435	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D0812_17445	ENOG4108UT2	hemolysin iii
D0812_17450	ENOG4108N23	SpoOM-related protein
D0812_17460	ENOG4105PC1	Conserved Protein
D0812_17470	ENOG4105E27	serine threonine protein kinase
D0812_17475	ENOG4108Z33	Thiol disulfide Interchange Protein
D0812_17480	ENOG4106HNH	Acyl-transferase
D0812_17490	ENOG4105C0P	Mg chelatase subunit ChlI
D0812_17500	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
D0812_17505	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D0812_17510	ENOG4105C01	Dihydroxy-acid dehydratase
D0812_17515	ENOG4105C7B	Threonine dehydratase
D0812_17520	ENOG4106TD9	Diguanylate cyclase
D0812_17525	ENOG4105F52	Transcriptional regulator
D0812_17530	ENOG4105CZQ	inner membrane transport protein YdhC
D0812_17540	ENOG4105EAD	ABC transporter
D0812_17545	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D0812_17550	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
D0812_17555	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
D0812_17560	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
D0812_17565	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
D0812_17570	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D0812_17575	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D0812_17580	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D0812_17585	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
D0812_17590	ENOG410684E	atp synthase
D0812_17595	ENOG4105FA0	parb-like partition protein
D0812_17600	ENOG4107QJE	Chromosome Partitioning Protein
D0812_17605	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
D0812_17610	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
D0812_17615	ENOG4105QTB	Flavodoxin
D0812_17620	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D0812_17625	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
D0812_17630	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
D0812_17635	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
D0812_17645	ENOG4105CDA	abc transporter atp-binding protein
D0812_17650	ENOG4105E5Q	amino acid AbC transporter
D0812_17655	ENOG4105EAB	amino acid AbC transporter
D0812_17660	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
D0812_17665	ENOG4105BZW	Glycerate kinase
D0812_17670	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D0812_17715	ENOG4108W0I	acetyltransferase
D0812_17735	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
D0812_17745	ENOG4105CUW	cytochrome C-TYPE protein
D0812_17750	ENOG4107QY8	reductase
D0812_17755	ENOG4105GR3	Histidine kinase
D0812_17765	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
D0812_17780	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
D0812_17785	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
D0812_17790	ENOG4105ETU	transcriptional activator (TenA
D0812_17795	ENOG4107Z6I	Thiamine biosynthesis protein
D0812_17800	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
D0812_17805	ENOG4108YI8	ABC transporter
D0812_17810	ENOG4105DWF	phosphomethylpyrimidine kinase
D0812_17825	ENOG4108TEM	pseudouridine methyltransferase
D0812_17880	ENOG4108YYI	Protein of unknown function (DUF2810)
D0812_17885	ENOG4105C5I	Dehydrogenase
D0812_17895	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
D0812_17900	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
D0812_17905	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D0812_17910	ENOG410804D	Sensor Signal Transduction Histidine Kinase
D0812_17935	ENOG4109015	Biopolymer transport protein exbD tolR
D0812_17980	ENOG4105DSE	periplasmic solute binding protein
D0812_17985	ENOG4105DIK	(ABC) transporter
D0812_17990	ENOG4105CC5	ABC transporter
D0812_18005	ENOG4105CUG	Oligopeptidase b
D0812_18010	ENOG4105E5M	Multidrug resistance protein D
D0812_18015	ENOG4105CYW	agmatinase
D0812_18020	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
D0812_18030	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D0812_18035	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D0812_18060	ENOG4108WAV	Transcriptional regulator
D0812_18090	ENOG4105CQZ	Histidine kinase
D0812_18095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_18100	ENOG4105BZU	Histidine kinase
D0812_18105	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
D0812_18125	ENOG4105D5U	fad dependent oxidoreductase
D0812_18140	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D0812_18145	ENOG4105C0F	tryptophanase EC 4.1.99.1
D0812_18165	ENOG4105D9N	nucleoside
D0812_18170	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
D0812_18190	ENOG4105BZU	Histidine kinase
D0812_18205	ENOG4106TD9	Diguanylate cyclase
D0812_18210	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D0812_18215	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
D0812_18230	ENOG4105E0X	reductase
D0812_18235	ENOG4108UKZ	OsmC family
D0812_18240	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
D0812_18270	ENOG4105JQN	Transcriptional regulator
D0812_18275	ENOG4105PAD	Hydrolase
D0812_18310	ENOG4105KUU	lipolytic protein G-D-S-L family
D0812_18315	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D0812_18340	ENOG4105ETE	Transcriptional regulator (LacI family
D0812_18345	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
D0812_18350	ENOG4108JPW	Aminotransferase
D0812_18355	ENOG4107STF	Involved in phosphonate degradation (By similarity)
D0812_18375	ENOG4107RCV	ABC transporter, permease
D0812_18395	ENOG4108MJ5	VirK protein
D0812_18405	ENOG4105CJP	fad dependent oxidoreductase
D0812_18420	ENOG4105ETT	transcriptional Regulator, LysR family
D0812_18440	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
D0812_18445	ENOG4105DUX	Transporter
D0812_18450	ENOG4105EJQ	L-serine dehydratase
D0812_18475	ENOG4105E9H	Lytic Murein transglycosylase
D0812_18495	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
D0812_18500	ENOG4108ZC9	flagellar basal-body rod protein flgc
D0812_18505	ENOG4105W00	Flagellar hook capping protein
D0812_18510	ENOG4105BZE	flagellar hook protein, FlgE
D0812_18515	ENOG4108KPB	Flagellar basal-body rod protein FlgF
D0812_18520	ENOG4105CGA	flagellar basal-body rod protein FlgG
D0812_18525	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D0812_18530	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D0812_18535	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
D0812_18540	ENOG4105E1Q	flagellar hook-associated protein
D0812_18545	ENOG4105DTJ	flagellar hook-associated protein
D0812_18565	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
D0812_18570	ENOG4105HEI	LysR family (Transcriptional regulator
D0812_18590	ENOG4105EE5	Membrane protein terC
D0812_18595	ENOG4108M3R	transcriptional activator CadC
D0812_18610	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
D0812_18640	ENOG4105F87	Dehydratase
D0812_18650	ENOG4105KWG	Pfam:DUF1696
D0812_18665	ENOG4105ER2	Ompa motb domain protein
D0812_18670	ENOG4107RD7	Flagellar Motor Protein, MotA
D0812_18695	ENOG4105MQ3	flagellar protein FliS
D0812_18700	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
D0812_18710	ENOG4105I03	Flagellin
D0812_18725	ENOG4105D00	flagellar biosynthetic protein flhB
D0812_18730	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
D0812_18735	ENOG4105VS8	Flagellar biosynthetic protein fliq
D0812_18740	ENOG4105CN7	Flagellar biosynthetic protein FliP
D0812_18745	ENOG4105DD5	Flagellar motor switch protein
D0812_18760	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_18770	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
D0812_18775	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D0812_18785	ENOG4108JIR	Flagellum-specific ATP synthase
D0812_18795	ENOG4105BZU	Histidine kinase
D0812_18810	ENOG4108EHX	EamA-like transporter family
D0812_18835	ENOG4107SSZ	Phosphatase
D0812_18855	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
D0812_18860	ENOG4105EXG	Transcriptional regulator
D0812_18880	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D0812_18900	ENOG4105BZU	Histidine kinase
D0812_18905	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D0812_18910	ENOG4105CPQ	Dehydrogenase
D0812_18970	ENOG4105D64	Mechanosensitive ion channel
D0812_18985	ENOG4105DMF	Dehydrogenase
D0812_18990	ENOG4105DAA	L-lactate
D0812_18995	ENOG4105CC0	LysR family Transcriptional regulator
D0812_19005	ENOG4108JQ5	ABC transporter
D0812_19015	ENOG4105DAN	ATP-dependent protease
D0812_19020	ENOG4108NVR	Methyl-accepting chemotaxis
D0812_19025	ENOG4107QE9	Inherit from COG: Membrane
D0812_19030	ENOG4105YE1	PilZ domain
D0812_19045	ENOG4108MK9	spermidine N(1)-acetyltransferase
D0812_19050	ENOG4108BGM	Quinol dehydrogenase periplasmic component
D0812_19055	ENOG4105GXZ	Ferredoxin-type protein NapH
D0812_19070	ENOG4105KBH	arsR family transcriptional regulator
D0812_19075	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D0812_19080	ENOG4105XEP	YhcH YjgK YiaL family protein
D0812_19095	ENOG4108JJB	ABC transporter
D0812_19100	ENOG4108V7D	UPF0397 protein
D0812_19105	ENOG4105EFX	secretion protein, HlyD family
D0812_19110	ENOG4105KK7	inner membrane protein YiaW
D0812_19120	ENOG4106TD9	Diguanylate cyclase
D0812_19135	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
D0812_19145	ENOG4107SEY	Conserved Protein
D0812_19150	ENOG4108XDN	Transcriptional regulator
D0812_19155	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D0812_19160	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
D0812_19170	ENOG4105C1J	atp-dependent rna helicase
D0812_19230	ENOG4105DZR	Type I site-specific deoxyribonuclease
D0812_19240	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D0812_19260	ENOG4105CUG	Oligopeptidase b
D0812_19265	ENOG4107ENK	receptor
D0812_19290	ENOG4107S17	Phosphate-binding protein
D0812_19295	ENOG4105C8U	phosphate abc transporter
D0812_19300	ENOG4105E2Z	phosphate ABC transporter (Permease
D0812_19305	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D0812_19340	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D0812_19360	ENOG41069D7	Methyl-accepting chemotaxis
D0812_19370	ENOG41086KC	Transcriptional regulator
D0812_19375	ENOG41086KC	Transcriptional regulator
D0812_19385	ENOG4108JJ6	Type I secretion system ATPase
D0812_19395	ENOG4108UW5	maltose o-acetyltransferase
D0812_19400	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_19405	ENOG4105BZU	Histidine kinase
D0812_19410	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
D0812_19415	ENOG4105C8U	phosphate abc transporter
D0812_19420	ENOG4105E2Z	phosphate ABC transporter (Permease
D0812_19425	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D0812_19430	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
D0812_19445	ENOG4105UYK	outer membrane protein a
D0812_19465	ENOG4105KCK	Peptidoglycan-associated lipoprotein
D0812_19475	ENOG4105BZU	Histidine kinase
D0812_19480	ENOG4105CK1	PTS System
D0812_19495	ENOG4105CEP	NADH dehydrogenase
D0812_19500	ENOG4105CK2	sodium dicarboxylate symporter
D0812_19510	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
D0812_19540	ENOG4105KK7	inner membrane protein YiaW
D0812_19545	ENOG4105EFX	secretion protein, HlyD family
D0812_19550	ENOG4105G2Y	Transcriptional regulator
D0812_19560	ENOG4105EIP	mannose-6-phosphate isomerase
D0812_19565	ENOG4105DM4	PTS System
D0812_19570	ENOG4106R3P	AraC family transcriptional regulator
D0812_19580	ENOG4108YRF	PTS System
D0812_19585	ENOG4105DM4	PTS System
D0812_19590	ENOG4105CBN	LysR family transcriptional regulator
D0812_19600	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D0812_19605	ENOG4105CH6	catalase
D0812_19615	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
D0812_19620	ENOG4108WUH	Transcriptional regulator, TetR family
D0812_19625	ENOG4105V0I	UPF0267 protein
D0812_19660	ENOG4107TYR	Glycosyl Transferase
D0812_19670	ENOG4105D75	Capsular exopolysaccharide family
D0812_19685	ENOG4105D3Q	Sugar transferase
D0812_19690	ENOG4108IJ9	(ABC) transporter
D0812_19700	ENOG4107FKK	extracellular solute-binding protein family 1
D0812_19705	ENOG4105D56	permease protein
D0812_19710	ENOG4105EG2	ABC transporter, permease
D0812_19740	ENOG4105CKW	Inner membrane protein yedI
D0812_19745	ENOG4105EKE	dihydroorotase
D0812_19755	ENOG4105QVC	MOSC domain-containing protein
D0812_19755	ENOG4105QVC	MOSC domain-containing protein
D0812_19760	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
D0812_19765	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
D0812_19805	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
D0812_19810	ENOG4105EHG	Permease protein
D0812_19820	ENOG4106GFD	transport protein
D0812_19825	ENOG41090AP	transport protein
D0812_19830	ENOG4105WQ5	TonB family
D0812_19835	ENOG4105D4P	Coproporphyrinogen iii oxidase
D0812_19840	ENOG41090JE	Utilization Protein
D0812_19845	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
D0812_19860	ENOG4107R88	Chemotaxis protein (CheV)
D0812_19865	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
D0812_19900	ENOG4105JQN	Transcriptional regulator
D0812_19930	ENOG4105EJC	lysr family transcriptional regulator
D0812_19950	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D0812_19955	ENOG4105G2Y	Transcriptional regulator
D0812_19990	ENOG4108W2Y	isochorismatase
D0812_19995	ENOG41063TF	transcriptional regulator (AraC
D0812_20000	ENOG4105EP9	oxidoreductase
D0812_20005	ENOG4105DIJ	Phosphoethanolamine transferase
D0812_20010	ENOG41080IJ	Diacylglycerol kinase
D0812_20020	ENOG4105JJR	Histidine kinase
D0812_20025	ENOG4107EXC	regulatoR
D0812_20030	ENOG4105C94	Transporter
D0812_20035	ENOG4105DIA	mandelate racemase muconate lactonizing
D0812_20040	ENOG4107EFR	Flavocytochrome c
D0812_20050	ENOG4105EMU	Dehydrogenase
D0812_20065	ENOG4108Z33	Thiol disulfide Interchange Protein
D0812_20085	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
D0812_20095	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
D0812_20110	ENOG4105EST	Metal Dependent Phosphohydrolase
D0812_20125	ENOG4105DZC	cytosine deaminase
D0812_20130	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
D0812_20135	ENOG4105CJW	magnesium transporter
D0812_20140	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
D0812_20145	ENOG4105EFX	secretion protein, HlyD family
D0812_20170	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D0812_20175	ENOG4105E0F	Histidine kinase
D0812_20205	ENOG4105DVH	amino acid
D0812_20210	ENOG4105EW9	transcriptional regulator AsnC family
D0812_20220	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
D0812_20240	ENOG4105BZU	Histidine kinase
D0812_20245	ENOG4105EE0	oxidoreductase
D0812_20255	ENOG41090HJ	UPF0265 protein
D0812_20265	ENOG4108YXG	UPF0502 protein
D0812_20270	ENOG41082IR	Excinuclease ABC C subunit domain protein
D0812_20275	ENOG4108QGH	periplasmic
D0812_20280	ENOG4105BZU	Histidine kinase
D0812_20295	ENOG4105EW9	transcriptional regulator AsnC family
D0812_20325	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D0812_20330	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D0812_20350	ENOG4105CHU	acetyl-coa acetyltransferase
D0812_20360	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
D0812_20380	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D0812_20395	ENOG4105BZU	Histidine kinase
D0812_20400	ENOG4105WH1	Two component transcriptional regulator luxr family
D0812_20415	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
D0812_20420	ENOG4107YWA	deoxycytidylate deaminase
D0812_20435	ENOG4108N3W	hemolysin secretion protein
D0812_20440	ENOG4108YZN	class I peptide chain release factor
D0812_20445	ENOG4107VXZ	Hydrolase
D0812_20475	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D0812_20485	ENOG4105CDV	Ompa motb domain protein
D0812_20505	ENOG4105VEQ	Cold shock protein
D0812_20520	ENOG4105BZU	Histidine kinase
D0812_20540	ENOG4107R39	(ABC) transporter
D0812_20550	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D0812_20570	ENOG4105DFG	type I secretion outer membrane protein
D0812_20575	ENOG4108MGY	Histidine kinase
D0812_20600	ENOG4108NVR	Methyl-accepting chemotaxis
D0812_20605	ENOG4108RMU	ferritin dps family protein
D0812_20615	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
D0812_20625	ENOG4105C0A	alcohol dehydrogenase
D0812_20630	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
D0812_20650	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D0812_20655	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D0812_20665	ENOG4105MIR	Phenylalanine 4-monooxygenase
D0812_20670	ENOG41090A4	Pterin carbinolamine dehydratase
D0812_20700	ENOG4105VRT	cytoplasmic protein
D0812_20720	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
D0812_20730	ENOG4105CKI	cobalamin synthesis protein
D0812_20735	ENOG4105BZU	Histidine kinase
D0812_20740	ENOG4105C1J	atp-dependent rna helicase
D0812_20760	ENOG4107XTP	(EAL) domain protein
D0812_20765	ENOG4105DKW	ABC transporter
D0812_20825	ENOG4107S17	Phosphate-binding protein
D0812_20840	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
D0812_20845	ENOG4105C1J	atp-dependent rna helicase
D0812_20855	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
D0812_20870	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
D0812_20890	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
D0812_20895	ENOG41060WC	Enoyl-CoA hydratase
D0812_20900	ENOG4107QX3	carboxylase
D0812_20905	ENOG4105C1G	acyl-Coa dehydrogenase
D0812_20915	ENOG4105CHU	acetyl-coa acetyltransferase
D0812_20920	ENOG4105C26	Dehydrogenase
D0812_20930	ENOG4105E39	Enoyl-CoA hydratase
D0812_20935	ENOG4105E39	Enoyl-CoA hydratase
D0812_20940	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D0812_20945	ENOG4105CHR	reductase
D0812_20955	ENOG4105E2S	oxidase) subunit II
D0812_20960	ENOG4105BZ9	Cytochrome C oxidase, subunit I
D0812_20965	ENOG4105CCU	oxidase (Subunit III)
D0812_20970	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
D0812_20975	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
D0812_20980	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D0812_20995	ENOG4105C26	Dehydrogenase
D0812_21070	ENOG4105E5Z	arginine transporter ATP-binding subunit
D0812_21075	ENOG4106PMH	Extracellular solute-binding protein family 3
D0812_21080	ENOG4105GBT	ABC transporter
D0812_21085	ENOG4105DMR	ABC, transporter
D0812_21090	ENOG4107RK6	Methyl-accepting chemotaxis
D0812_21100	ENOG4105DUM	transcriptional regulator, lysR family
D0812_21110	ENOG4105ENH	Sulfatase
D0812_21115	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
D0812_21135	ENOG4105EXG	Transcriptional regulator
D0812_21140	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
D0812_21145	ENOG4105BZJ	Electron transfer flavoprotein
D0812_21150	ENOG4105C10	Electron transfer flavoprotein
D0812_21155	ENOG4107QSN	dihydrolipoamide acetyltransferase
D0812_21160	ENOG4105CPP	Dehydrogenase, E1 component
D0812_21165	ENOG4107RUY	(E1 component), alpha subunit
D0812_21180	ENOG4105R8A	Heat shock protein
D0812_21185	ENOG4106E5D	Protein of unknown function (DUF461)
D0812_21215	ENOG4105ETX	regulatoR
D0812_21230	ENOG4105G6Z	alkaline phosphatase
D0812_21255	ENOG4105BZU	Histidine kinase
D0812_21265	ENOG4105C44	Serine transporter
D0812_21270	ENOG4105BZU	Histidine kinase
D0812_21315	ENOG4105DG7	nitrate ABC transporter
D0812_21320	ENOG4105D7T	ABC transporter
D0812_21325	ENOG4107QZF	nitrite reductase NADPH large subunit
D0812_21355	ENOG4105F8J	Adenylate Guanylate cyclase
D0812_21365	ENOG4105BZU	Histidine kinase
D0812_21375	ENOG4105ETX	regulatoR
D0812_21380	ENOG4105F3H	Histidine kinase
D0812_21385	ENOG4106855	Competence protein
D0812_21390	ENOG4105ETX	regulatoR
D0812_21405	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D0812_21415	ENOG4105GTN	ParB Domain Protein Nuclease
D0812_21430	ENOG4108NIW	Leucine export protein LeuE
D0812_21435	ENOG4105CIC	tryptophan-specific transport protein
D0812_21445	ENOG4108RU0	short-chain dehydrogenase reductase
D0812_21450	ENOG4107HP6	Transcriptional regulator
D0812_21460	ENOG4105Q9Y	Universal stress protein
D0812_21470	ENOG4105D65	subunit l
D0812_21475	ENOG4108ZE9	Monovalent cation H antiporter subunit C
D0812_21480	ENOG4108JPZ	Monovalent cation H antiporter subunit D
D0812_21485	ENOG4105SC1	monovalent cation H antiporter subunit E
D0812_21490	ENOG41080TA	Multiple resistance and ph regulation protein f
D0812_21495	ENOG4105KJM	monovalent cation h antiporter subunit g
D0812_21500	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
D0812_21505	ENOG4105C4M	(Ubiquinol oxidase) subunit I
D0812_21515	ENOG4105G2Y	Transcriptional regulator
D0812_21525	ENOG4105DR5	peptidase
D0812_21560	ENOG4105IPI	Membrane
D0812_21580	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
D0812_21620	ENOG4105FTV	AraC Family Transcriptional Regulator
D0812_21635	ENOG4105SBG	acid phosphatase
D0812_21690	ENOG4105BZ1	(ABC) transporter
D0812_21715	ENOG4105CR8	Transcriptional regulator
D0812_21735	ENOG4105CNH	Multidrug resistance protein MdtL
D0812_21760	ENOG4105ESI	atpase involved in dna repair
D0812_21770	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D0812_21775	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
D0812_21780	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D0812_21795	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
D0812_21805	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
D0812_21840	ENOG4105DM4	PTS System
D0812_21845	ENOG4105DE4	1-phosphofructokinase
D0812_21850	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
D0812_21855	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
D0812_21870	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
D0812_21875	ENOG4105DRP	amino acid AbC transporter
D0812_21880	ENOG4106TNF	Periplasmic binding protein
D0812_21940	ENOG4108HJ1	Uncharacterized conserved protein (DUF2303)
D0812_21965	ENOG4106CVF	DNA replication protein
D0812_22230	ENOG4105EAD	ABC transporter
D0812_22235	ENOG4105CDA	abc transporter atp-binding protein
D0812_22245	ENOG4108I6A	alcohol dehydrogenase
D0812_22250	ENOG4105CF7	AraC family transcriptional regulator
D0812_22260	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
D0812_22265	ENOG4105CKU	formyltetrahydrofolate synthetase
D0812_22270	ENOG4107RE1	Inosine-guanosine kinase
D0812_22285	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D0812_22290	ENOG4107YBY	Hydrolase
D0812_22300	ENOG4108N3W	hemolysin secretion protein
D0812_22310	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
D0812_22315	ENOG4105C1J	atp-dependent rna helicase
D0812_22320	ENOG4108M8H	domain protein
D0812_22335	ENOG4105DS1	cytochrome b561
D0812_22340	ENOG4108YYC	ycei family
D0812_22345	ENOG4105TMB	Formate nitrite transporter
D0812_22355	ENOG4105DUM	transcriptional regulator, lysR family
D0812_22360	ENOG4108UQ5	membrane protein YcdZ
D0812_22365	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
D0812_22370	ENOG4105CGH	5'-nucleotidase
D0812_22375	ENOG4105DU1	integral membrane protein, terc
D0812_22390	ENOG4105C3R	Methionine synthase
D0812_22405	ENOG4108M0H	Extracellular lipase
D0812_22410	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
D0812_22425	ENOG4105KA0	thioesterase Superfamily protein
D0812_22460	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D0812_22470	ENOG4105BZU	Histidine kinase
D0812_22475	ENOG4105RKW	reductase (By
D0812_22485	ENOG4108I0Y	(ABC) transporter
D0812_22490	ENOG4105CV6	ABC transporter, permease
D0812_22505	ENOG4105P4J	Allophanate hydrolase, subunit 1
D0812_22510	ENOG4105E7W	lamb ycsf family protein
D0812_22515	ENOG4105BZU	Histidine kinase
D0812_22520	ENOG4105CMR	udp-glucose 4-epimerase
D0812_22535	ENOG4105CWB	LysR family transcriptional Regulator
D0812_22540	ENOG4105CD5	CoA-binding domain protein
D0812_22550	ENOG4105CPF	Cell wall formation (By similarity)
D0812_22560	ENOG4108ZJT	translation initiation factor, Sui1
D0812_22605	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D0812_22610	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D0812_22635	ENOG4105BZU	Histidine kinase
D0812_22660	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
D0812_22665	ENOG4105E0C	molybdate abc transporter
D0812_22670	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
D0812_22675	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
D0812_22680	ENOG4105WXI	Bacterial OB fold (BOF) protein
D0812_22695	ENOG4105CGF	Aromatic amino acid aminotransferase
D0812_22700	ENOG4105ECQ	AraC Family Transcriptional Regulator
D0812_22705	ENOG4107QI1	Mate efflux family protein
D0812_22710	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
D0812_22715	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
D0812_22795	ENOG4105CXY	transporter
D0812_22800	ENOG4108KX4	response regulator
D0812_22805	ENOG4105BZU	Histidine kinase
D0812_22810	ENOG4105CXY	transporter
D0812_22815	ENOG4105EIP	mannose-6-phosphate isomerase
D0812_22825	ENOG4105IPI	Membrane
D0812_22835	ENOG4105EFX	secretion protein, HlyD family
D0812_22865	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D0812_22870	ENOG4105K63	Thioredoxin
D0812_22875	ENOG4108ISG	Major Facilitator
D0812_22885	ENOG4107QI1	Mate efflux family protein
D0812_22890	ENOG4105VXR	cytoplasmic protein
D0812_22905	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
D0812_22920	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D0812_22925	ENOG4105TMB	Formate nitrite transporter
D0812_22930	ENOG4105WZK	nitrite reductase NADPH small subunit
D0812_22935	ENOG4107QZF	nitrite reductase NADPH large subunit
D0812_22945	ENOG4108KHX	Diguanylate cyclase
D0812_23020	ENOG4105CXG	d-lactate dehydrogenase
D0812_23025	ENOG4105CBN	LysR family transcriptional regulator
D0812_23030	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D0812_23045	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
D0812_23050	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
D0812_23060	ENOG4105C5W	Aldolase
D0812_23070	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
D0812_23080	ENOG4105C2C	drug resistance transporter, Bcr CflA
D0812_23090	ENOG4105QNF	Outer membrane lipoprotein
D0812_23130	ENOG4105E03	chitinase
D0812_23140	ENOG4105EYH	Exonuclease
D0812_23145	ENOG4107RFY	SbcCD D subunit
D0812_23170	ENOG4105CS6	Rhs element vgr protein
D0812_23180	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D0812_23225	ENOG4108ZF3	Phosphatase
D0812_23240	ENOG4106VK6	Flagellar motor protein
D0812_23260	ENOG4105D9P	serine threonine protein kinase
D0812_23300	ENOG4108UYE	Lactoylglutathione lyase
D0812_23305	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D0812_23315	ENOG4105EXC	Acyl-transferase
D0812_23330	ENOG4105CBC	glutamate synthase
D0812_23340	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
D0812_23345	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
D0812_23355	ENOG4107RGH	Aldehyde dehydrogenase
D0812_23375	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
D0812_23380	ENOG4105KPY	Small multidrug resistance protein
D0812_23395	ENOG4106CKV	Pap2 superfamily protein
D0812_23410	ENOG4105FR1	rard protein
D0812_23420	ENOG4108VAU	general secretion pathway protein G
D0812_23425	ENOG4107R88	Chemotaxis protein (CheV)
D0812_23430	ENOG4108TVJ	Nitroreductase
D0812_23440	ENOG4108WQH	regulatoR
D0812_23450	ENOG4105BZU	Histidine kinase
D0812_23455	ENOG4108WQH	regulatoR
D0812_23460	ENOG4105BZU	Histidine kinase
D0812_23465	ENOG4105BZU	Histidine kinase
D0812_23470	ENOG4105BZU	Histidine kinase
D0812_23480	ENOG4105D05	Receptor
D0812_23535	ENOG4105EW9	transcriptional regulator AsnC family
D0812_23570	ENOG4105D9P	serine threonine protein kinase
D0812_23595	ENOG4105CS6	Rhs element vgr protein
D0812_23600	ENOG4108WC9	type VI secretion system effector, hcp1 family
D0812_23605	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D0812_23610	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_23615	ENOG4105KCK	Peptidoglycan-associated lipoprotein
D0812_23635	ENOG4105DR5	peptidase
D0812_23640	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
D0812_23645	ENOG4107KBT	8-Amino-7-oxononanoate synthase
D0812_23650	ENOG4108MGY	Histidine kinase
D0812_23670	ENOG4105CEE	C4-dicarboxylate transporter
D0812_23675	ENOG4108V0P	LemA family
D0812_23680	ENOG4105D0M	Protease HtpX homolog
D0812_23700	ENOG4105F2V	VRR-NUC domain-containing protein
D0812_23710	ENOG4105C4X	radical SAM domain protein
D0812_23730	ENOG4108YDI	single-species biofilm formation on inanimate substrate
D0812_23735	ENOG4107TE5	Lipid kinase
D0812_23740	ENOG41064T2	transcriptional regulator, lysR family
D0812_23745	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D0812_23750	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
D0812_23755	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
D0812_23760	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
D0812_23765	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
D0812_23770	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D0812_23775	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
D0812_23780	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D0812_23785	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
D0812_23820	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D0812_23830	ENOG4105ENH	Sulfatase
D0812_23835	ENOG4105DQS	Transcriptional regulator
D0812_23845	ENOG4105ENH	Sulfatase
D0812_23850	ENOG4105ENH	Sulfatase
D0812_23855	ENOG4105ENH	Sulfatase
D0812_23865	ENOG410804D	Sensor Signal Transduction Histidine Kinase
D0812_23885	ENOG4105BZU	Histidine kinase
D0812_23890	ENOG4108SV3	Tmao reductase system periplasmic protein tort
D0812_23895	ENOG4108Z5K	methylglyoxal synthase
D0812_23900	ENOG41088T4	Helicase IV
D0812_23905	ENOG4105EM2	membrane
D0812_23940	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D0812_23950	ENOG4108Z6Z	Transcriptional regulator
D0812_23955	ENOG4108IPW	abc transporter atp-binding protein
D0812_23960	ENOG4105CM4	permease protein
D0812_23965	ENOG4105DHS	permease protein
D0812_23985	ENOG4108I5U	Uridine phosphorylase
D0812_23990	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
D0812_24000	ENOG4105ETE	Transcriptional regulator (LacI family
D0812_24005	ENOG4108RVA	ribokinase
D0812_24010	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
D0812_24015	ENOG4105CNN	ABC, transporter
D0812_24020	ENOG4105C2J	ABC transporter
D0812_24025	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
D0812_24030	ENOG4108K0B	C-di-gmp phosphodiesterase
D0812_24035	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
D0812_24070	ENOG4106W5V	Membrane
D0812_24100	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D0812_24105	ENOG4105BZU	Histidine kinase
D0812_24135	ENOG4105HEI	LysR family (Transcriptional regulator
D0812_24145	ENOG4105BZU	Histidine kinase
D0812_24150	ENOG4105CA0	peroxidase
D0812_24155	ENOG4105BZU	Histidine kinase
D0812_24160	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
D0812_24190	ENOG4107QX8	SPFH domain, Band 7 family protein
D0812_24200	ENOG4108RCM	Nitroreductase
D0812_24245	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
D0812_24255	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
D0812_24270	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
D0812_24285	ENOG4105E2K	Glycosyl transferase (Group 1
D0812_24310	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
D0812_24315	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
D0812_24320	ENOG4105C11	sulfate adenylyltransferase), subunit 2
D0812_24325	ENOG4105D75	Capsular exopolysaccharide family
D0812_24330	ENOG4105DAY	polysaccharide export protein
D0812_24335	ENOG4105D3Q	Sugar transferase
D0812_24340	ENOG4108IJ7	Glycine betaine
D0812_24345	ENOG4108HQS	Glycine betaine
D0812_24355	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
D0812_24360	ENOG4105C26	Dehydrogenase
D0812_24365	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
D0812_24370	ENOG4107RGH	Aldehyde dehydrogenase
D0812_24380	ENOG4105BZU	Histidine kinase
D0812_24390	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
D0812_24425	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
D0812_24430	ENOG4105C4C	beta-galactosidase
D0812_24440	ENOG4105EG2	ABC transporter, permease
D0812_24450	ENOG4107FKK	extracellular solute-binding protein family 1
D0812_24475	ENOG41060NJ	transcriptional regulator
D0812_24480	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D0812_24485	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
D0812_24490	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
D0812_24495	ENOG4105CMR	udp-glucose 4-epimerase
D0812_24520	ENOG4108ZHR	arsR family transcriptional regulator
D0812_24550	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_24570	ENOG4107XZC	Restriction modification system DNA (Specificity
D0812_24575	ENOG4105CVR	type I restriction-modification system
D0812_24585	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_24620	ENOG4105F8X	type iii restriction
D0812_24640	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D0812_24645	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
D0812_24655	ENOG4108UNF	response regulator
D0812_24660	ENOG4107RGM	aldo keto reductase
D0812_24685	ENOG4105C5A	transporter
D0812_24695	ENOG4105EUJ	GTP cyclohydrolase i
D0812_24700	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D0812_24705	ENOG4105D06	uba thif-type nad fad binding protein
D0812_24725	ENOG4105KHC	sulfurtransferase
D0812_24730	ENOG4105BZU	Histidine kinase
D0812_24750	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
D0812_24760	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
D0812_24765	ENOG4105DXI	Major Facilitator superfamily
D0812_24770	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
D0812_24775	ENOG4105UYK	outer membrane protein a
D0812_24780	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
D0812_24785	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
D0812_24810	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
D0812_24855	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
D0812_24870	ENOG4108SXK	Transporter Drug Metabolite Exporter family
D0812_24890	ENOG4105E5M	Multidrug resistance protein D
D0812_24895	ENOG4105CR8	Transcriptional regulator
D0812_24900	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
D0812_24910	ENOG4105E0K	tonB-dependent siderophore receptor
D0812_24915	ENOG4105HFT	AraC family transcriptional regulator
D0812_24925	ENOG4105E0A	ABC, transporter
D0812_24935	ENOG4105DR5	peptidase
D0812_24960	ENOG4105DWD	nucleoside recognition domain protein
D0812_24965	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_24975	ENOG4105E0U	tyrosine-specific transport protein
D0812_25000	ENOG4107Z1W	Fructose transport system kinase
D0812_25010	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
D0812_25015	ENOG4105CTS	PTS system mannitol-specific
D0812_25020	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
D0812_25025	ENOG4105FDP	GntR family transcriptional regulator
D0812_25030	ENOG4105DM4	PTS System
D0812_25035	ENOG4105C8I	hydrolase, family 38
D0812_25040	ENOG4105EIP	mannose-6-phosphate isomerase
D0812_25050	ENOG4107RGM	aldo keto reductase
D0812_25055	ENOG4105JQN	Transcriptional regulator
D0812_25070	ENOG4105KVH	Transcriptional regulator
D0812_25085	ENOG4105D6J	arsenicaL-resistance protein
D0812_25100	ENOG4108V1U	phospholipid-binding protein
D0812_25105	ENOG4105JAB	phenazine biosynthesis protein, phzf family
D0812_25110	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
D0812_25115	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
D0812_25120	ENOG4105E2D	ec 3.2.1.52
D0812_25130	ENOG4108UHU	Aldolase
D0812_25135	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D0812_25140	ENOG4108IA2	Sodium pantothenate symporter
D0812_25165	ENOG4108NVR	Methyl-accepting chemotaxis
D0812_25175	ENOG4105CJ1	ABC, transporter
D0812_25180	ENOG4107QWP	ABC-2 type transporter
D0812_25195	ENOG4108IEG	Formate dehydrogenase Alpha subunit
D0812_25220	ENOG4108IJF	Heavy metal efflux pump, CzcA
D0812_25265	ENOG4105M6F	mutator MutT protein
D0812_25280	ENOG4105CA0	peroxidase
D0812_25290	ENOG4108HK0	-acetyltransferase
D0812_25300	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
D0812_25315	ENOG4105C5H	ABC transporter
D0812_25340	ENOG4108M6U	Universal stress protein A
D0812_25350	ENOG4105E98	transcriptional regulator DeoR family
D0812_25365	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
D0812_25370	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
D0812_25375	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D0812_25395	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
D0812_25415	ENOG4105CKI	cobalamin synthesis protein
D0812_25425	ENOG4105CD3	dihydroorotase
D0812_25435	ENOG4108NRW	Phospholipase, patatin family
D0812_25445	ENOG4105EUB	pirin domain protein
D0812_25450	ENOG4105VEQ	Cold shock protein
D0812_25465	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
D0812_25470	ENOG4105BZU	Histidine kinase
D0812_25495	ENOG4105DMQ	Methyltransferase
D0812_25505	ENOG4105BZU	Histidine kinase
D0812_25510	ENOG4105DZ1	carboxypeptidase
D0812_25515	ENOG4105C94	Transporter
D0812_25520	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D0812_25525	ENOG4105JQN	Transcriptional regulator
D0812_25530	ENOG4105CYM	Glutathione S-transferase
D0812_25540	ENOG4105NAE	bifunctional deaminase-reductase domain protein
D0812_25550	ENOG4105CHR	reductase
D0812_25575	ENOG4108P3C	
D0812_25590	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
D0812_25600	ENOG4105EJC	lysr family transcriptional regulator
D0812_25605	ENOG410874W	AraC family transcriptional regulator
D0812_25610	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D0812_25640	ENOG4105C1J	atp-dependent rna helicase
D0812_25650	ENOG4105ETT	transcriptional Regulator, LysR family
D0812_25675	ENOG4105CHR	reductase
D0812_25680	ENOG4105F27	Major Facilitator
D0812_25690	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D0812_25705	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
D0812_25710	ENOG4105DDW	LysR family Transcriptional regulator
D0812_25735	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D0812_25750	ENOG4105HDK	L-asparaginase
D0812_25755	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
D0812_25760	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
D0812_25770	ENOG4108S01	response regulator
D0812_25775	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D0812_25785	ENOG4105G2Y	Transcriptional regulator
D0812_25825	ENOG4105HEI	LysR family (Transcriptional regulator
D0812_25830	ENOG4107V40	secretion protein, HlyD family
D0812_25840	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
D0812_25845	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
D0812_25850	ENOG4105D6U	Sodium Glutamate Symporter
D0812_25865	ENOG4105BZU	Histidine kinase
D0812_25875	ENOG41086KC	Transcriptional regulator
D0812_25890	ENOG4105CEY	Amp-dependent synthetase and ligase
D0812_25910	ENOG4105BZS	acriflavin resistance protein
D0812_25925	ENOG4105BZS	acriflavin resistance protein
D0812_25935	ENOG4107RZC	phospholipase d
D0812_25965	ENOG4108Z4X	TRANSCRIPTIONal
D0812_25980	ENOG4108HKT	sucrose-6-phosphate hydrolase
D0812_25985	ENOG4105C5Y	PTS System
D0812_25990	ENOG4105FDP	GntR family transcriptional regulator
D0812_26005	ENOG4107S8C	mandelate racemase muconate lactonizing
D0812_26015	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D0812_26025	ENOG4105BZU	Histidine kinase
D0812_26050	ENOG4105VYW	UPF0251 protein
D0812_26060	ENOG4108HQS	Glycine betaine
D0812_26065	ENOG4108IJ7	Glycine betaine
D0812_26080	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
D0812_26085	ENOG4105ETT	transcriptional Regulator, LysR family
D0812_26110	ENOG4105RA2	Membrane
D0812_26125	ENOG4107RH7	Nicotinate phosphoribosyltransferase
D0812_26135	ENOG4108RWI	nicotinamidase
D0812_26140	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D0812_26150	ENOG4105CH6	catalase
D0812_26170	ENOG4105EIP	mannose-6-phosphate isomerase
D0812_26175	ENOG4105C87	Aminotransferase class I and II
D0812_26180	ENOG4105CI1	PTS System
D0812_26185	ENOG4107P2S	Transcriptional regulator
D0812_26190	ENOG4105N2W	Transcriptional regulator
D0812_26195	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
D0812_26200	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D0812_26215	ENOG4105DM4	PTS System
D0812_26220	ENOG4105CWX	Alpha-1,2-mannosidase
D0812_26225	ENOG4105CWX	Alpha-1,2-mannosidase
D0812_26235	ENOG4105CWX	Alpha-1,2-mannosidase
D0812_26240	ENOG4105CWX	Alpha-1,2-mannosidase
D0812_26245	ENOG4105CGH	5'-nucleotidase
D0812_26275	ENOG4105N14	lysine exporter protein LysE YggA
D0812_26280	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
D0812_26295	ENOG4105W1N	transcriptional regulator
D0812_26310	ENOG4105HEI	LysR family (Transcriptional regulator
D0812_26325	ENOG4105C5H	ABC transporter
D0812_26340	ENOG4105Q8W	reductase
D0812_26345	ENOG4105HEI	LysR family (Transcriptional regulator
D0812_26350	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
D0812_26355	ENOG4105C5H	ABC transporter
D0812_26370	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
D0812_26375	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
D0812_26390	ENOG4105E18	UPF0276 protein
D0812_26405	ENOG4105C4M	(Ubiquinol oxidase) subunit I
D0812_26410	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
D0812_26445	ENOG4107U2T	alpha beta
D0812_26450	ENOG4105E7U	AraC family transcriptional regulator
D0812_26455	ENOG41075H3	AraC family transcriptional regulator
D0812_26465	ENOG4105C6N	Formate acetyltransferase
D0812_26470	ENOG4105F1A	Pyruvate formate-lyase
D0812_26475	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
D0812_26490	ENOG4105EB3	Histidine kinase
D0812_26495	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D0812_26505	ENOG4105I4A	GCN5-related N-acetyltransferase
D0812_26510	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
D0812_26520	ENOG4105CNH	Multidrug resistance protein MdtL
D0812_26525	ENOG4105G2Y	Transcriptional regulator
D0812_26535	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
D0812_26575	ENOG4105IPI	Membrane
D0812_26580	ENOG41068P6	UPF0319 protein
D0812_26595	ENOG4105DP0	ferredoxin-NADP reductase
D0812_26605	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
D0812_26610	ENOG4105EJC	lysr family transcriptional regulator
D0812_26620	ENOG4108RCM	Nitroreductase
D0812_26635	ENOG4105DZ1	carboxypeptidase
D0812_26655	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D0812_26660	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D0812_26665	ENOG4105C72	UPF0176 protein
D0812_26685	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D0812_26700	ENOG4108NRW	Phospholipase, patatin family
D0812_26705	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
D0812_26715	ENOG4105DAY	polysaccharide export protein
D0812_26720	ENOG4107ZF2	Phosphatase
D0812_26735	ENOG4105N0V	mono-oxygenase ydhR
D0812_26740	ENOG4105C5Q	Transcriptional regulator
D0812_26745	ENOG4105F27	Major Facilitator
D0812_26775	ENOG4105CK2	sodium dicarboxylate symporter
D0812_26785	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D0812_26790	ENOG4108P2H	Inner membrane protein YjiG
D0812_26795	ENOG41074DU	domain protein
D0812_26810	ENOG4107T9C	Alpha amylase catalytic region
D0812_26820	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
D0812_26825	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D0812_26830	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
D0812_26835	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
D0812_26840	ENOG41061ZR	Transcriptional regulator
D0812_26865	ENOG4105CI1	PTS System
D0812_26870	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
D0812_26875	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
D0812_26905	ENOG4105EDK	PfkB domain protein
D0812_26910	ENOG4105CIB	oxidoreductase Domain protein
D0812_26915	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
D0812_26925	ENOG4107QNK	)-transporter
D0812_26945	ENOG4105CHU	acetyl-coa acetyltransferase
D0812_26950	ENOG4107QP7	CoA-transferase subunit A
D0812_26965	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
D0812_26975	ENOG4105D5Q	Arginine ornithine antiporter
D0812_26980	ENOG4105CXN	decarboxylase
D0812_27000	ENOG4108K8S	endonuclease I
D0812_27025	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
D0812_27035	ENOG4105BZU	Histidine kinase
D0812_27045	ENOG4105D5B	Sulfite reductase, subunit A
D0812_27050	ENOG4107SHJ	sulfite reductase subunit b
D0812_27055	ENOG410810Y	Sulfite reductase
D0812_27060	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
D0812_27075	ENOG4105C5Y	PTS System
D0812_27080	ENOG4105CHR	reductase
D0812_27085	ENOG4105EJQ	L-serine dehydratase
D0812_27095	ENOG4105D2S	major facilitator superfamily
D0812_27110	ENOG4105ETE	Transcriptional regulator (LacI family
D0812_27120	ENOG4105E5M	Multidrug resistance protein D
D0812_27125	ENOG4105T0Z	Conserved Protein
D0812_27135	ENOG4105D05	Receptor
D0812_27155	ENOG4105DHS	permease protein
D0812_27160	ENOG4105CM4	permease protein
D0812_27165	ENOG4108IPW	abc transporter atp-binding protein
D0812_27170	ENOG41062JF	Transcriptional regulator
D0812_27195	ENOG4105DR5	peptidase
D0812_27210	ENOG4108UHU	Aldolase
D0812_27215	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D0812_27220	ENOG4105C5Y	PTS System
D0812_27230	ENOG4105FDP	GntR family transcriptional regulator
D0812_27235	ENOG4107QW3	Sucrose phosphorylase
D0812_27240	ENOG4108HKT	sucrose-6-phosphate hydrolase
D0812_27250	ENOG4108IJ9	(ABC) transporter
D0812_27255	ENOG4107URF	beta-phospho-glucomutase
D0812_27260	ENOG4105C71	hydrolase family 65, central catalytic
D0812_27265	ENOG4105DRS	transport system, permease
D0812_27270	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
D0812_27300	ENOG4108FZ9	Chaperone
D0812_27305	ENOG4106PG1	outer membrane usher protein
D0812_27335	ENOG4107RAN	Peptidase, M16
D0812_27340	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_27355	ENOG4105CFP	Peptidase U32
D0812_27385	ENOG4108WTW	DNA transposition protein
D0812_27415	ENOG4106V8H	Nucleoid-associated protein
D0812_27470	ENOG4108E1C	hydrolase
D0812_27615	ENOG4105CPC	Aldo Keto reductase
D0812_27625	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D0812_27635	ENOG410642W	LysR family Transcriptional regulator
D0812_27645	ENOG4105C19	ABC transporter
D0812_27695	ENOG4108ZHJ	Organic hydroperoxide resistance protein
D0812_27700	ENOG4105K56	Transcriptional regulator
D0812_27705	ENOG4105D3R	alkyl hydroperoxide reductase
D0812_27710	ENOG4108JU3	Alkyl hydroperoxide reductase
D0812_27730	ENOG4105FDP	GntR family transcriptional regulator
D0812_27735	ENOG4105DJB	Major Facilitator Superfamily
D0812_27740	ENOG4108TFM	Kinase, PfkB family
D0812_27745	ENOG4108KD5	ADP-ribosylation crystallin J1
D0812_27750	ENOG4105EAA	nucleoside
D0812_27770	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
D0812_27775	ENOG4108N3W	hemolysin secretion protein
D0812_27785	ENOG4105F4I	Transcriptional regulator
D0812_27795	ENOG4108XM1	transcriptional regulator AsnC family
D0812_27810	ENOG4108RPX	mosc domain containing protein
D0812_27815	ENOG41060NJ	transcriptional regulator
D0812_27820	ENOG4105DFD	Na H antiporter
D0812_27825	ENOG4105C87	Aminotransferase class I and II
D0812_27830	ENOG4105C1J	atp-dependent rna helicase
D0812_27845	ENOG4105EXG	Transcriptional regulator
D0812_27850	ENOG410904A	RNA polymerase
D0812_27860	ENOG4105C87	Aminotransferase class I and II
D0812_27865	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
D0812_27870	ENOG4105C6F	GntR Family Transcriptional Regulator
D0812_27875	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
D0812_27880	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
D0812_27885	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D0812_27890	ENOG4105DEI	Mannitol dehydrogenase
D0812_27900	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
D0812_27905	ENOG4108UHU	Aldolase
D0812_27910	ENOG4105P66	Membrane
D0812_27915	ENOG4105EJ2	Transcriptional regulator
D0812_27925	ENOG410839U	amino acid
D0812_27955	ENOG4105BZ1	(ABC) transporter
D0812_27965	ENOG4105EW9	transcriptional regulator AsnC family
D0812_27980	ENOG4105CVJ	phosphoglycerate mutase
D0812_27985	ENOG4105KNA	-acetyltransferase
D0812_28005	ENOG4105CK7	Sodium proline symporter
D0812_28015	ENOG4105C26	Dehydrogenase
D0812_28030	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
D0812_28035	ENOG4105CQZ	Histidine kinase
D0812_28040	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D0812_28045	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
D0812_28060	ENOG4108JJA	ABC, transporter
D0812_28075	ENOG4108J59	Extracellular solute-binding protein, family 5
D0812_28085	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
D0812_28090	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D0812_28095	ENOG4105C5Y	PTS System
D0812_28100	ENOG4105FCK	Membrane
D0812_28110	ENOG4105EQ2	LysR family Transcriptional regulator
D0812_28125	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
D0812_28130	ENOG4106RMF	ParB family
D0812_28160	ENOG4108JQ7	(ABC) transporter
D0812_28185	ENOG4105BZU	Histidine kinase
D0812_28195	ENOG4105CDY	transcriptional regulatory protein
D0812_28200	ENOG4105CNI	cell division protein FtsW
D0812_28215	ENOG4105Y49	secretion protein, HlyD family
D0812_28220	ENOG4105CR8	Transcriptional regulator
D0812_28230	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D0812_28250	ENOG4108HRK	Histidine kinase
D0812_28255	ENOG4108VAC	response regulator
D0812_28265	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D0812_28270	ENOG4105C8Q	Methyl-accepting chemotaxis
D0812_28290	ENOG4105D6U	Sodium Glutamate Symporter
D0812_28305	ENOG4105CZV	ABC transporter
D0812_28310	ENOG4107U9B	transcriptional regulator
D0812_28315	ENOG4105D6U	Sodium Glutamate Symporter
D0812_28340	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D0812_28355	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
D0812_28360	ENOG4108YZ9	Urea amidohydrolase subunit gamma
D0812_28365	ENOG4105KI2	Urea amidohydrolase subunit beta
D0812_28370	ENOG4105CQM	Urea amidohydrolase subunit alpha
D0812_28375	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
D0812_28380	ENOG4105IY8	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
D0812_28385	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
D0812_28395	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
D0812_28400	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
D0812_28410	ENOG4105EHG	Permease protein
D0812_28430	ENOG4105KME	endoribonuclease L-psp
D0812_28435	ENOG4105NXH	GreA GreB family elongation factor
D0812_28485	ENOG4108K4B	hydrolase
D0812_28495	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
D0812_28515	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
D0812_28535	ENOG4105C2I	pirin domain protein
D0812_28540	ENOG4108VGI	doxx family
D0812_28550	ENOG4105D03	DNA-3-methyladenine glycosylase II
D0812_28555	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D0812_28575	ENOG4105DN9	Na H antiporter
D0812_28690	ENOG4105NBK	UPF0345 protein
D0812_28700	ENOG4108K0B	C-di-gmp phosphodiesterase
D0812_28705	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
D0812_28710	ENOG41060NJ	transcriptional regulator
D0812_28725	ENOG4105DRS	transport system, permease
D0812_28735	ENOG4108IJ9	(ABC) transporter
D0812_28740	ENOG4105ETE	Transcriptional regulator (LacI family
D0812_28745	ENOG4105UQX	Mate efflux family protein
D0812_28750	ENOG4105D3G	Pseudouridine synthase
D0812_28765	ENOG4108HCJ	Hydrolase
D0812_28775	ENOG4108KHX	Diguanylate cyclase
D0812_28785	ENOG4105KAF	membrAne
D0812_28805	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
D0812_28820	ENOG4105CC0	LysR family Transcriptional regulator
D0812_28830	ENOG4105EGI	Transcriptional regulator
D0812_28835	ENOG4105Q26	Siderophore-interacting protein
D0812_28850	ENOG4105EW9	transcriptional regulator AsnC family
D0812_28855	ENOG4108M1A	Chitin-binding protein
D0812_28865	ENOG410814C	multidrug resistance protein
D0812_28880	ENOG4107W31	Pentapeptide repeat protein
D0812_28885	ENOG4105EIF	outer membrane protein W
D0812_28905	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
D0812_28925	ENOG4107WCA	isomerase
D0812_28940	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
D0812_28980	ENOG4105G2Y	Transcriptional regulator
D0812_28995	ENOG4105D9N	nucleoside
D0812_29005	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D0812_29030	ENOG4105CI2	imidazolone-5-propionate hydrolase
D0812_29235	ENOG4108J1Q	
D0812_29260	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D0812_29340	ENOG4105CJN	penicillin-binding protein
D0812_29375	ENOG4107QJE	Chromosome Partitioning Protein
D0812_29490	ENOG4105DR5	peptidase
D0812_29505	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
D0812_29525	ENOG4107VGF	ig domain protein group 2 domain protein
D0812_29550	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D0812_29560	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
D0812_29615	ENOG4105RWF	major outer membrane protein OmpA
D0812_29645	ENOG4105UYK	outer membrane protein a
D0812_29650	ENOG4107VGF	ig domain protein group 2 domain protein
D0812_29670	ENOG4108IYH	Dna topoisomerase
D0812_29885	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
D0812_29910	ENOG4107WZZ	SMC domain protein
D0812_29970	ENOG4107U4J	modification