locus-tag	class	description
APZ19_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
APZ19_00015	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
APZ19_00020	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
APZ19_00025	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APZ19_00030	ENOG4108ZNX	Heat shock protein
APZ19_00035	ENOG4105JKW	Valine--pyruvate aminotransferase
APZ19_00110	ENOG4105EB3	Histidine kinase
APZ19_00120	ENOG4107T9C	Alpha amylase catalytic region
APZ19_00125	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
APZ19_00130	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
APZ19_00145	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
APZ19_00160	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
APZ19_00165	ENOG4105CHU	acetyl-coa acetyltransferase
APZ19_00170	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APZ19_00175	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
APZ19_00180	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
APZ19_00185	ENOG4108RR8	protoporphyrinogen oxidase
APZ19_00225	ENOG4105E3B	Multicopper oxidase
APZ19_00230	ENOG4105WMR	Protein CrcB homolog
APZ19_00235	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
APZ19_00245	ENOG4105D06	uba thif-type nad fad binding protein
APZ19_00250	ENOG4105WHD	thiamine biosynthesis protein ThiS
APZ19_00255	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
APZ19_00260	ENOG4105D41	biosynthesis protein thiH
APZ19_00265	ENOG4105DC7	peptidase M24
APZ19_00265	ENOG4105DC7	peptidase M24
APZ19_00270	ENOG4105G2Y	Transcriptional regulator
APZ19_00275	ENOG4105CNH	Multidrug resistance protein MdtL
APZ19_00295	ENOG4105E18	UPF0276 protein
APZ19_00305	ENOG4105C4R	Atp-dependent dna helicase
APZ19_00315	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
APZ19_00330	ENOG4105FR1	rard protein
APZ19_00335	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APZ19_00345	ENOG4105EX9	Membrane
APZ19_00355	ENOG4105C9X	ppx gppa phosphatase
APZ19_00360	ENOG4105C1J	atp-dependent rna helicase
APZ19_00365	ENOG4105K63	Thioredoxin
APZ19_00370	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
APZ19_00380	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
APZ19_00385	ENOG4108ZIT	Ferredoxin, 2FE-2S
APZ19_00390	ENOG4107QK7	reductase
APZ19_00435	ENOG4105ECF	c-methyltransferase
APZ19_00440	ENOG41076E6	Uroporphyrinogen-III Synthase
APZ19_00445	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
APZ19_00450	ENOG4107T0K	Adenylate cyclase
APZ19_00455	ENOG4105XQ6	frataxin-like protein
APZ19_00465	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
APZ19_00470	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
APZ19_00480	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APZ19_00485	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
APZ19_00490	ENOG4105BZU	Histidine kinase
APZ19_00495	ENOG4106IUH	DTW domain containing protein
APZ19_00510	ENOG4105DQF	Hydrolase
APZ19_00515	ENOG4108EUD	Lysophospholipase
APZ19_00520	ENOG410829K	Lysine exporter protein (Lyse ygga)
APZ19_00525	ENOG4105D58	Diguanylate phosphodiesterase
APZ19_00530	ENOG41082YX	Transcriptional regulator, arsr family
APZ19_00535	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
APZ19_00585	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
APZ19_00595	ENOG4106H78	methyltransferase
APZ19_00600	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APZ19_00600	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
APZ19_00605	ENOG4105CAK	Cell division ATP-binding protein ftsE
APZ19_00610	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
APZ19_00615	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APZ19_00620	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
APZ19_00625	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
APZ19_00630	ENOG4105X6C	Flagellar basal body-associated protein FliL
APZ19_00635	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
APZ19_00640	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
APZ19_00645	ENOG4105E55	glycerol-3-phosphate acyltransferase
APZ19_00650	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
APZ19_00660	ENOG4107R73	Mate efflux family protein
APZ19_00665	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
APZ19_00680	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
APZ19_00685	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APZ19_00695	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
APZ19_00765	ENOG4105JIM	Phosphatidylserine synthase
APZ19_00775	ENOG4105D4A	Cell wall formation (By similarity)
APZ19_00780	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
APZ19_00785	ENOG4105CS9	pantothenic acid kinase
APZ19_00810	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
APZ19_00825	ENOG4105PM1	preprotein translocase subunit SecE
APZ19_00830	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
APZ19_00835	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
APZ19_00840	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
APZ19_00845	ENOG4108VZM	50s ribosomal protein L10
APZ19_00850	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
APZ19_00855	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APZ19_00860	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APZ19_00865	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
APZ19_00870	ENOG4105E09	nadh pyrophosphatase
APZ19_00875	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
APZ19_00880	ENOG4108RG0	uracil-dna glycosylase
APZ19_00885	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
APZ19_00890	ENOG4105R2J	Conserved Protein
APZ19_00910	ENOG4105C12	Phosphoribosylglycinamide synthetase
APZ19_00915	ENOG4105DC1	bifunctional purine biosynthesis protein purh
APZ19_00920	ENOG4105W1Y	Transcriptional regulator
APZ19_00925	ENOG4108M3R	transcriptional activator CadC
APZ19_00930	ENOG4105D5Q	Arginine ornithine antiporter
APZ19_00935	ENOG4105CXN	decarboxylase
APZ19_00980	ENOG4105BZU	Histidine kinase
APZ19_00985	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
APZ19_00990	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
APZ19_00995	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
APZ19_01005	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
APZ19_01010	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
APZ19_01015	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
APZ19_01020	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
APZ19_01035	ENOG4105D8G	Major Facilitator superfamily
APZ19_01040	ENOG4105BZU	Histidine kinase
APZ19_01045	ENOG4105C9Q	fumarate hydratase class II
APZ19_01060	ENOG4107QN1	sodium solute
APZ19_01070	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
APZ19_01080	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
APZ19_01085	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
APZ19_01090	ENOG4108IJ0	Aspartate ammonia-lyase
APZ19_01095	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
APZ19_01100	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
APZ19_01110	ENOG4105E0F	Histidine kinase
APZ19_01115	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
APZ19_01120	ENOG4108SPG	Periplasmic Protein
APZ19_01125	ENOG41076HS	cation diffusion facilitator family transporter
APZ19_01130	ENOG4105CTQ	phosphohexokinase
APZ19_01135	ENOG4107QI1	Mate efflux family protein
APZ19_01140	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
APZ19_01145	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
APZ19_01160	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
APZ19_01165	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
APZ19_01180	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
APZ19_01185	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
APZ19_01200	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
APZ19_01210	ENOG41062JF	Transcriptional regulator
APZ19_01220	ENOG41063SB	peptidase
APZ19_01225	ENOG4105D7W	serine acetyltransferase
APZ19_01230	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
APZ19_01235	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
APZ19_01240	ENOG4107YZP	Rhodanese domain protein
APZ19_01245	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
APZ19_01255	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_01260	ENOG4105C8P	)-transporter
APZ19_01270	ENOG4105DJ4	phosphatidylserine decarboxylase
APZ19_01275	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
APZ19_01280	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
APZ19_01355	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
APZ19_01360	ENOG4105K8N	protein family UPF0079, ATPase
APZ19_01365	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
APZ19_01370	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
APZ19_01375	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
APZ19_01380	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
APZ19_01385	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
APZ19_01390	ENOG4107QJR	hflk protein
APZ19_01395	ENOG4105EPW	hflc protein
APZ19_01405	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
APZ19_01415	ENOG4108UV7	flagellar protein motX
APZ19_01420	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
APZ19_01425	ENOG4105KPV	Transcriptional regulator
APZ19_01430	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
APZ19_01435	ENOG4105C2N	RNA methyltransferase TrmH family group 3
APZ19_01440	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APZ19_01445	ENOG4105C31	Tryptophanyl-tRNA synthetase
APZ19_01455	ENOG4105DDQ	anthranilate synthase
APZ19_01460	ENOG4105C8Y	Acetylornithine aminotransferase
APZ19_01470	ENOG4105C26	Dehydrogenase
APZ19_01480	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
APZ19_01485	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
APZ19_01490	ENOG4105YP7	UPF0270 protein
APZ19_01495	ENOG4105DNZ	Alpha Beta Hydrolase
APZ19_01505	ENOG4105C5H	ABC transporter
APZ19_01515	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
APZ19_01530	ENOG4108YZY	peptidylprolyl cis-trans isomerase
APZ19_01540	ENOG4105D44	asparaginase
APZ19_01545	ENOG41069P5	Protein slyX homolog
APZ19_01555	ENOG4108V1T	peptidylprolyl cis-trans isomerase
APZ19_01560	ENOG4105WWK	YheO domain protein
APZ19_01565	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
APZ19_01570	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
APZ19_01575	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
APZ19_01580	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
APZ19_01585	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
APZ19_01590	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
APZ19_01595	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
APZ19_01600	ENOG4105W53	bacterioferritin-associated ferredoxin
APZ19_01605	ENOG4108UQY	Iron-storage protein
APZ19_01610	ENOG4105C6K	Malic enzyme
APZ19_01615	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
APZ19_01620	ENOG4105C28	cystathionine
APZ19_01625	ENOG4105CFH	Aspartokinase
APZ19_01630	ENOG4105SYT	Methylenetetrahydrofolate reductase
APZ19_01640	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
APZ19_01645	ENOG4105CWC	Acetylornithine deacetylase
APZ19_01650	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
APZ19_01655	ENOG4105CAS	nag kinase
APZ19_01660	ENOG4105CDH	Citrulline--aspartate ligase
APZ19_01665	ENOG4105CH7	arginosuccinase
APZ19_01680	ENOG4107QN2	dihydrolipoyl dehydrogenase
APZ19_01685	ENOG4105EHV	domain protein
APZ19_01695	ENOG4108JQC	penicillin-binding protein 1A
APZ19_01720	ENOG4105E4G	Type IV pilus
APZ19_01725	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
APZ19_01730	ENOG4105D49	3-dehydroquinate synthase
APZ19_01740	ENOG4105DFE	Dna adenine methylase
APZ19_01745	ENOG4105DJV	ribulose-phosphate 3-epimerase
APZ19_01750	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
APZ19_01755	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
APZ19_01760	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
APZ19_01765	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
APZ19_01775	ENOG4105CDU	Replicative dna helicase
APZ19_01780	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
APZ19_01790	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
APZ19_01795	ENOG4107QP8	phosphohexose isomerase
APZ19_01805	ENOG4105MYN	Zinc uptake regulation protein
APZ19_01810	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
APZ19_01830	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
APZ19_01835	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
APZ19_01840	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
APZ19_01890	ENOG4105EEQ	Na H antiporter
APZ19_01895	ENOG4105C3R	Methionine synthase
APZ19_01900	ENOG4105CFH	Aspartokinase
APZ19_01905	ENOG4105C5R	Aminotransferase
APZ19_01915	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
APZ19_01920	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
APZ19_01925	ENOG41086KC	Transcriptional regulator
APZ19_01930	ENOG4108UUM	single-stranded DNA-binding protein
APZ19_01935	ENOG41062P1	Diguanylate cyclase phosphodiesterase
APZ19_01970	ENOG4107QHF	type ii secretion system protein e
APZ19_01975	ENOG4105D7Q	type ii secretion system
APZ19_01985	ENOG4108VAU	general secretion pathway protein G
APZ19_02020	ENOG4105DFF	Rod shape-determining protein mreb
APZ19_02025	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
APZ19_02030	ENOG4105VQ7	Rod shape-determining protein MreD
APZ19_02035	ENOG4108Z03	MAF-like protein
APZ19_02040	ENOG4105C03	ribonuclease
APZ19_02045	ENOG4105QD6	exported protein
APZ19_02055	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
APZ19_02060	ENOG4108IAB	Phoh family
APZ19_02065	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
APZ19_02070	ENOG4105K3M	)-transporter
APZ19_02075	ENOG4105D3G	Pseudouridine synthase
APZ19_02080	ENOG4105C5I	Dehydrogenase
APZ19_02085	ENOG4105N42	UPF0307 protein
APZ19_02090	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
APZ19_02095	ENOG4105CJW	magnesium transporter
APZ19_02100	ENOG41080Z8	PHOSPHOCARRIER protein
APZ19_02105	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
APZ19_02110	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
APZ19_02115	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
APZ19_02120	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APZ19_02125	ENOG4108IUZ	ABC transporter
APZ19_02130	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
APZ19_02140	ENOG4105C2X	Arabinose 5-phosphate isomerase
APZ19_02150	ENOG4105DHJ	ABC, transporter
APZ19_02155	ENOG4105CY3	ABC transporter, permease
APZ19_02160	ENOG4107PE3	Mammalian cell entry related domain protein
APZ19_02165	ENOG4105E3I	toluene tolerance
APZ19_02175	ENOG4105VFK	BolA family
APZ19_02180	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
APZ19_02185	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
APZ19_02190	ENOG4105KME	endoribonuclease L-psp
APZ19_02195	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
APZ19_02200	ENOG4105CXT	aspartate transcarbamylase
APZ19_02210	ENOG4105DBV	ornithine carbamoyltransferase
APZ19_02215	ENOG4105CEU	Arginine dihydrolase
APZ19_02230	ENOG4108MJ3	acetyltransferase
APZ19_02240	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
APZ19_02245	ENOG4105MYG	DNA polymerase iii, chi subunit
APZ19_02250	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
APZ19_02255	ENOG4108M8S	permease YjgP YjgQ family protein
APZ19_02260	ENOG4108K5H	permease YjgP YjgQ family protein
APZ19_02270	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
APZ19_02285	ENOG4105VZJ	PTS System
APZ19_02295	ENOG4105VCP	PTS System
APZ19_02300	ENOG4105F8D	glycoside hydrolase family 4
APZ19_02305	ENOG410901P	UPF0249 protein
APZ19_02310	ENOG4105ETE	Transcriptional regulator (LacI family
APZ19_02315	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
APZ19_02370	ENOG4105C26	Dehydrogenase
APZ19_02400	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_02445	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
APZ19_02450	ENOG4105CEN	a g-specific adenine glycosylase
APZ19_02455	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
APZ19_02465	ENOG4105CSV	Glutaminase
APZ19_02470	ENOG4105CSA	Coproporphyrinogen iii oxidase
APZ19_02475	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
APZ19_02485	ENOG4105VZ9	UPF0235 protein
APZ19_02490	ENOG4108VIA	integral membrane protein
APZ19_02495	ENOG4105II7	pyrroline-5-carboxylate reductase
APZ19_02500	ENOG4105DFA	alanine racemase domain protein
APZ19_02505	ENOG4105CZX	twitching motility protein
APZ19_02510	ENOG4105CZX	twitching motility protein
APZ19_02515	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
APZ19_02520	ENOG4108UJU	UPF0301 protein
APZ19_02525	ENOG4105D7Z	glutathione synthase
APZ19_02530	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
APZ19_02535	ENOG4105RWS	endonuclease I
APZ19_02540	ENOG4105GPY	SprT protein
APZ19_02550	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
APZ19_02555	ENOG4105CV1	Transketolase (EC 2.2.1.1)
APZ19_02565	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
APZ19_02570	ENOG4105BZA	Phosphoglycerate kinase
APZ19_02575	ENOG4105D2N	Aldolase
APZ19_02580	ENOG4105D64	Mechanosensitive ion channel
APZ19_02595	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
APZ19_02600	ENOG4105MPN	Membrane
APZ19_02605	ENOG4108JQ1	Dehydrogenase
APZ19_02610	ENOG4105E66	phosphoriboisomerase A
APZ19_02615	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
APZ19_02625	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
APZ19_02640	ENOG4105D0A	hydroxylase
APZ19_02645	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
APZ19_02660	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
APZ19_02665	ENOG4105Y75	tpr repeat protein
APZ19_02675	ENOG4108IYU	L-aspartate oxidase
APZ19_02685	ENOG4105EMN	RNA polymerase sigma factor
APZ19_02695	ENOG4105VQK	sigma E regulatory protein, MucB RseB
APZ19_02705	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
APZ19_02710	ENOG4105C3F	Signal peptidase i
APZ19_02715	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
APZ19_02720	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
APZ19_02725	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
APZ19_02730	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
APZ19_02735	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
APZ19_02740	ENOG4105BZU	Histidine kinase
APZ19_02745	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
APZ19_02750	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APZ19_02755	ENOG4105DXN	mazG family
APZ19_02760	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
APZ19_02765	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
APZ19_02770	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
APZ19_02775	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
APZ19_02780	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
APZ19_02785	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
APZ19_02790	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
APZ19_02795	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
APZ19_02805	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APZ19_02810	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
APZ19_02815	ENOG4107TH8	cina domain protein
APZ19_02820	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
APZ19_02825	ENOG4105Y3E	Modulates RecA activity (By similarity)
APZ19_02830	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
APZ19_02835	ENOG4105CFH	Aspartokinase
APZ19_02840	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
APZ19_02905	ENOG41086KC	Transcriptional regulator
APZ19_02915	ENOG4107QSA	Oxaloacetate decarboxylase
APZ19_02920	ENOG4105D9Q	decarboxylase (Beta subunit)
APZ19_02930	ENOG4105W39	Membrane
APZ19_02940	ENOG4105D9M	gamma-glutamylcysteine synthetase
APZ19_02950	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
APZ19_02955	ENOG4108JU6	CBS domain protein
APZ19_02960	ENOG4106KVJ	cytochrome C assembly protein
APZ19_02965	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APZ19_02970	ENOG4105K5M	30s ribosomal protein S16
APZ19_02975	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
APZ19_02980	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
APZ19_02985	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
APZ19_02990	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
APZ19_02995	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
APZ19_03000	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
APZ19_03005	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
APZ19_03010	ENOG4105D7Q	type ii secretion system
APZ19_03015	ENOG4107QHF	type ii secretion system protein e
APZ19_03025	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
APZ19_03035	ENOG41073TP	transcriptional regulator
APZ19_03040	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
APZ19_03045	ENOG4107QSN	dihydrolipoamide acetyltransferase
APZ19_03050	ENOG4107QN2	dihydrolipoyl dehydrogenase
APZ19_03055	ENOG410630P	Transcriptional regulator
APZ19_03060	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
APZ19_03065	ENOG41077A9	carbonic anhydrase
APZ19_03070	ENOG4105CHH	sulfate transporter
APZ19_03075	ENOG4105DA5	(ABC) transporter
APZ19_03080	ENOG4105E3A	(ABC) transporter
APZ19_03085	ENOG4105D1S	lipid A biosynthesis
APZ19_03090	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
APZ19_03095	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
APZ19_03100	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APZ19_03105	ENOG4105DJ0	Poly(A) Polymerase
APZ19_03110	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
APZ19_03115	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
APZ19_03120	ENOG4105PW4	Sugar fermentation stimulation protein homolog
APZ19_03125	ENOG4105CQ7	ATP-dependent helicase
APZ19_03130	ENOG4105BZ4	penicillin-binding protein
APZ19_03135	ENOG4105D78	K07001 NTE family protein
APZ19_03140	ENOG4107QIJ	Aconitate hydratase 2
APZ19_03145	ENOG4105XTV	UPF0231 protein
APZ19_03150	ENOG4108YZA	Nitrogen regulatory protein pii
APZ19_03170	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
APZ19_03185	ENOG4105E2D	ec 3.2.1.52
APZ19_03190	ENOG4105RD7	BadF BadG BcrA BcrD
APZ19_03200	ENOG4108JQ7	(ABC) transporter
APZ19_03205	ENOG4105C3U	ABC transporter
APZ19_03210	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APZ19_03220	ENOG4107QRA	Extracellular solute-binding protein, family 5
APZ19_03225	ENOG4105BZU	Histidine kinase
APZ19_03230	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
APZ19_03235	ENOG4105F4G	Membrane
APZ19_03240	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
APZ19_03245	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
APZ19_03255	ENOG4105BZS	acriflavin resistance protein
APZ19_03260	ENOG4105DR5	peptidase
APZ19_03265	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
APZ19_03275	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
APZ19_03280	ENOG4107QE9	Inherit from COG: Membrane
APZ19_03285	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
APZ19_03290	ENOG4105HBR	Rna-binding protein
APZ19_03295	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
APZ19_03300	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
APZ19_03305	ENOG4105EEI	dihydropteroate synthase
APZ19_03310	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
APZ19_03330	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
APZ19_03335	ENOG4105CHV	Transcription elongation factor NusA
APZ19_03340	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
APZ19_03345	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
APZ19_03350	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
APZ19_03355	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
APZ19_03360	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
APZ19_03375	ENOG4105C3S	Mate efflux family protein
APZ19_03380	ENOG4106RZ4	Peptidase U32
APZ19_03385	ENOG4105CFP	Peptidase U32
APZ19_03390	ENOG4105BZU	Histidine kinase
APZ19_03395	ENOG4105XPQ	lipid carrier protein
APZ19_03400	ENOG4108YYD	acetyltransferase
APZ19_03420	ENOG4105BZU	Histidine kinase
APZ19_03425	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
APZ19_03430	ENOG4105EYA	deoxyribonuclease
APZ19_03435	ENOG4105D9N	nucleoside
APZ19_03440	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
APZ19_03445	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
APZ19_03450	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
APZ19_03455	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
APZ19_03465	ENOG4105EAC	phosphoserine phosphatase
APZ19_03475	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
APZ19_03480	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
APZ19_03485	ENOG4105ETT	transcriptional Regulator, LysR family
APZ19_03520	ENOG4108IQE	Amp-dependent synthetase and ligase
APZ19_03525	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
APZ19_03600	ENOG4105CDV	Ompa motb domain protein
APZ19_03610	ENOG41064T2	transcriptional regulator, lysR family
APZ19_03615	ENOG4107WCA	isomerase
APZ19_03620	ENOG4107W6W	Conserved Protein
APZ19_03625	ENOG4105E5D	amino acid
APZ19_03630	ENOG4105FK9	beta-D-galactosidase beta subunit
APZ19_03635	ENOG4105CNT	hydrolase family 2
APZ19_03640	ENOG4105CQ4	Transcriptional regulator
APZ19_03645	ENOG4105CJN	penicillin-binding protein
APZ19_03650	ENOG4105CMR	udp-glucose 4-epimerase
APZ19_03655	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
APZ19_03660	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
APZ19_03665	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
APZ19_03670	ENOG41060NJ	transcriptional regulator
APZ19_03675	ENOG4105CI1	PTS System
APZ19_03685	ENOG4108Y51	tRNA-binding protein
APZ19_03705	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
APZ19_03710	ENOG4105E98	transcriptional regulator DeoR family
APZ19_03715	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
APZ19_03720	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
APZ19_03730	ENOG4105CXY	transporter
APZ19_03735	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
APZ19_03750	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
APZ19_03765	ENOG4105X2V	dna damage-inducible protein
APZ19_03770	ENOG4105EVZ	LysR family transcriptional regulator
APZ19_03780	ENOG4105E68	Sulfatase
APZ19_03785	ENOG4105DSY	exodeoxyribonuclease V, gamma
APZ19_03790	ENOG4107QKA	exodeoxyribonuclease V beta
APZ19_03795	ENOG4107QYX	exodeoxyribonuclease v alpha
APZ19_03810	ENOG4107QZM	n-acetylglutamate synthase
APZ19_03820	ENOG4105CA3	membrane-bound lytic murein transglycosylase
APZ19_03825	ENOG4105CUZ	uba thif-type nad fad binding protein
APZ19_03830	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
APZ19_03835	ENOG4105C9B	Cysteine desulfurase
APZ19_03840	ENOG4107S0N	DJ-1 family
APZ19_03845	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
APZ19_03850	ENOG4105DRB	nucleoside-specific channel-forming protein
APZ19_03870	ENOG4105K6V	RNA polymerase
APZ19_03885	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
APZ19_03895	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
APZ19_03900	ENOG4105M85	Bola protein
APZ19_03905	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APZ19_03910	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APZ19_03915	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APZ19_03920	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APZ19_03925	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APZ19_03930	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
APZ19_03935	ENOG4105CJ2	(LipO)protein
APZ19_03945	ENOG4105BZU	Histidine kinase
APZ19_03950	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
APZ19_03955	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APZ19_03960	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
APZ19_03975	ENOG4105C8J	)-transporter
APZ19_03985	ENOG4105W1I	UPF0253 protein
APZ19_03995	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
APZ19_04000	ENOG4108R96	Methyltransferase, YaeB family
APZ19_04005	ENOG4105NRA	50s ribosomal protein l31 type b
APZ19_04015	ENOG4105CFC	Transporter
APZ19_04025	ENOG4108UPT	UPF0178 protein
APZ19_04050	ENOG4105WP7	tRNA pseudouridine synthase C
APZ19_04055	ENOG4105DR9	pseudouridine synthase
APZ19_04060	ENOG4108T8E	UPF0325 protein
APZ19_04065	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
APZ19_04070	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
APZ19_04075	ENOG4105CE9	30S ribosomal protein S2
APZ19_04080	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
APZ19_04085	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
APZ19_04090	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
APZ19_04095	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
APZ19_04100	ENOG4105KNE	Phosphatidate cytidylyltransferase
APZ19_04105	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
APZ19_04110	ENOG4105DZP	Membrane-associated zinc metalloprotease
APZ19_04120	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
APZ19_04125	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APZ19_04130	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
APZ19_04135	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APZ19_04140	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APZ19_04145	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APZ19_04150	ENOG4105C0B	DNA polymerase III (alpha subunit)
APZ19_04155	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
APZ19_04160	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
APZ19_04165	ENOG4105N7H	Cytochrome
APZ19_04170	ENOG4108YZA	Nitrogen regulatory protein pii
APZ19_04175	ENOG4107NA1	Endonuclease Exonuclease phosphatase
APZ19_04185	ENOG4105E9H	Lytic Murein transglycosylase
APZ19_04190	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
APZ19_04195	ENOG4105D1A	Methyltransferase
APZ19_04200	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
APZ19_04205	ENOG4107RZZ	dna polymerase iii epsilon subunit
APZ19_04225	ENOG4107QPN	acyl-Coa dehydrogenase
APZ19_04230	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
APZ19_04235	ENOG4105E7A	Glutamine amidotransferase
APZ19_04240	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
APZ19_04245	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
APZ19_04250	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
APZ19_04255	ENOG4105C2W	permease
APZ19_04270	ENOG4105CS1	NAD(P)H quinone oxidoreductase
APZ19_04275	ENOG4105K89	arsenate reductase
APZ19_04280	ENOG4105ERG	peptidase m48, ste24p
APZ19_04295	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APZ19_04300	ENOG4105RH4	Glycine cleavage system transcriptional repressor
APZ19_04310	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
APZ19_04325	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
APZ19_04330	ENOG4105KUZ	arsenate reductase
APZ19_04350	ENOG4105QZU	Inner membrane protein YfeZ
APZ19_04355	ENOG4105EZR	dyp-type peroxidase family protein
APZ19_04360	ENOG4108K2B	transcriptional regulator
APZ19_04365	ENOG4105F8D	glycoside hydrolase family 4
APZ19_04370	ENOG4105CT4	transporter
APZ19_04380	ENOG4105I03	Flagellin
APZ19_04390	ENOG4105I03	Flagellin
APZ19_04395	ENOG4105I03	Flagellin
APZ19_04400	ENOG41063QE	flagellar protein FlaG
APZ19_04405	ENOG4107BRV	flagellar capping protein
APZ19_04415	ENOG4105MQ3	flagellar protein FliS
APZ19_04420	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_04425	ENOG4105BZU	Histidine kinase
APZ19_04430	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_04435	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
APZ19_04440	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
APZ19_04445	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
APZ19_04455	ENOG4108JIR	Flagellum-specific ATP synthase
APZ19_04480	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
APZ19_04485	ENOG4105DD5	Flagellar motor switch protein
APZ19_04490	ENOG4105VTB	flagellar biosynthesis protein fliO
APZ19_04495	ENOG4105CN7	Flagellar biosynthetic protein FliP
APZ19_04500	ENOG4105VS8	Flagellar biosynthetic protein fliq
APZ19_04505	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
APZ19_04510	ENOG4105D00	flagellar biosynthetic protein flhB
APZ19_04515	ENOG4105D7B	Flagellar biosynthesis protein flha
APZ19_04520	ENOG4105FZW	flagellar biosynthesis regulator FlhF
APZ19_04525	ENOG4107R21	site-determining protein
APZ19_04530	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APZ19_04535	ENOG4108VYJ	response regulator receiver protein
APZ19_04540	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
APZ19_04545	ENOG4105CBS	Chea signal transduction histidine kinase
APZ19_04550	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APZ19_04555	ENOG4107QJE	Chromosome Partitioning Protein
APZ19_04565	ENOG4108V3W	Chemotaxis protein, CheW
APZ19_04575	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
APZ19_04580	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
APZ19_04585	ENOG41060IM	Heme exporter protein
APZ19_04595	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
APZ19_04600	ENOG4105DA4	cytochrome c-type biogenesis protein
APZ19_04605	ENOG4107QX9	Thiol disulfide interChange protein
APZ19_04610	ENOG4108M1T	Cytochrome c-type biogenesis protein
APZ19_04615	ENOG4105KWW	Biogenesis protein
APZ19_04620	ENOG410903C	(LipO)protein
APZ19_04625	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
APZ19_04630	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
APZ19_04645	ENOG4105CHU	acetyl-coa acetyltransferase
APZ19_04650	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
APZ19_04655	ENOG4107QXK	peptidase
APZ19_04660	ENOG4108BY2	phosphohistidine phosphatase
APZ19_04665	ENOG4108DG9	Smr protein MutS2
APZ19_04670	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
APZ19_04675	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
APZ19_04680	ENOG4105EN6	Membrane
APZ19_04685	ENOG4108BPE	-transporting atpase
APZ19_04690	ENOG4105MH2	YfcL protein
APZ19_04700	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
APZ19_04705	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
APZ19_04710	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
APZ19_04715	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
APZ19_04725	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
APZ19_04730	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
APZ19_04735	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
APZ19_04740	ENOG4108S3P	Sporulation domain protein
APZ19_04745	ENOG4105E96	Colicin v production protein
APZ19_04750	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
APZ19_04755	ENOG4105EJC	lysr family transcriptional regulator
APZ19_04760	ENOG4105I93	response regulator
APZ19_04770	ENOG4105WD1	Membrane
APZ19_04775	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
APZ19_04780	ENOG4107QMP	dna polymerase iii subunits gamma and tau
APZ19_04785	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
APZ19_04790	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
APZ19_04795	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
APZ19_04800	ENOG4105C44	Serine transporter
APZ19_04810	ENOG4105CEM	UPF0597 protein
APZ19_04815	ENOG4105WWK	YheO domain protein
APZ19_04820	ENOG4105KRS	Proteinase inhibitor
APZ19_04830	ENOG4108ZZ3	UPF0260 protein
APZ19_04835	ENOG4105Y3U	Transglycosylase-associated protein
APZ19_04840	ENOG4105D0C	transport protein
APZ19_04845	ENOG4105CVK	Glutamate decarboxylase
APZ19_04860	ENOG4108UYE	Lactoylglutathione lyase
APZ19_04870	ENOG4105G6Z	alkaline phosphatase
APZ19_04885	ENOG4105DHI	Methyltransferase
APZ19_04890	ENOG4107SDU	Methyl-accepting chemotaxis
APZ19_04905	ENOG4105DSB	aldose 1-epimerase
APZ19_04910	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
APZ19_04915	ENOG4105E0X	reductase
APZ19_04925	ENOG4105VUT	cytoplasmic protein
APZ19_04930	ENOG4105HDK	L-asparaginase
APZ19_04935	ENOG4105D07	Signal peptide peptidase, SppA
APZ19_04940	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APZ19_04945	ENOG41069NU	Nitroreductase
APZ19_04950	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
APZ19_04960	ENOG4108RU0	short-chain dehydrogenase reductase
APZ19_04965	ENOG4105DGU	Histone deacetylase
APZ19_04970	ENOG4108M3P	Membrane
APZ19_04985	ENOG4105E68	Sulfatase
APZ19_04990	ENOG4105YDX	UPF0352 protein
APZ19_04995	ENOG4106V8H	Nucleoid-associated protein
APZ19_05010	ENOG4105DFD	Na H antiporter
APZ19_05015	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
APZ19_05020	ENOG4105X0D	Fimbrial protein
APZ19_05025	ENOG4105EYW	Ion transport protein
APZ19_05030	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
APZ19_05035	ENOG4108EKI	Dehydrogenase
APZ19_05050	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APZ19_05055	ENOG4105M2J	Glutaredoxin
APZ19_05060	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APZ19_05105	ENOG4105UYK	outer membrane protein a
APZ19_05170	ENOG4105W5Q	DNA repair protein (RadC
APZ19_05245	ENOG4108PCE	TRANSFER protein
APZ19_05305	ENOG4105D3Y	Na H antiporter
APZ19_05310	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
APZ19_05315	ENOG4105EIY	sodium-type flagellar protein motY
APZ19_05320	ENOG4106WH9	Protein of unknown function (DUF2753)
APZ19_05325	ENOG4108UYE	Lactoylglutathione lyase
APZ19_05330	ENOG4105CSM	endonuclease III
APZ19_05335	ENOG4105DZB	Electron transport complex
APZ19_05340	ENOG4108UQQ	Electron transport complex
APZ19_05345	ENOG4105D6A	Electron transport complex
APZ19_05355	ENOG4108R3D	Electron transport complex
APZ19_05360	ENOG4105DGN	Electron transport complex
APZ19_05365	ENOG4105C6N	Formate acetyltransferase
APZ19_05380	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
APZ19_05385	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_05395	ENOG4105CHW	UPF0052 protein
APZ19_05400	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APZ19_05405	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
APZ19_05410	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
APZ19_05415	ENOG4105M00	molybdopterin converting factor, subunit 1
APZ19_05420	ENOG4108ZAF	Molybdopterin
APZ19_05425	ENOG4107QSI	ABC, transporter
APZ19_05430	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
APZ19_05435	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APZ19_05440	ENOG4105C3U	ABC transporter
APZ19_05445	ENOG4108JQ7	(ABC) transporter
APZ19_05450	ENOG4105CHF	Glutathione S-transferase
APZ19_05455	ENOG4107PU6	Membrane
APZ19_05465	ENOG4108DNC	Involved in acetate metabolism (By similarity)
APZ19_05470	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
APZ19_05475	ENOG4105PQ6	UPF0208 membrane protein
APZ19_05485	ENOG4105C7J	ABC transporter, permease
APZ19_05490	ENOG4108JJB	ABC transporter
APZ19_05495	ENOG4107R28	alpha amylase, catalytic region
APZ19_05505	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
APZ19_05510	ENOG4106RHG	Yeca family
APZ19_05515	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
APZ19_05520	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
APZ19_05525	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
APZ19_05550	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
APZ19_05555	ENOG4105D1F	ATP-binding protein
APZ19_05560	ENOG4105DBI	uridine monophosphokinase
APZ19_05570	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
APZ19_05580	ENOG4105CHH	sulfate transporter
APZ19_05585	ENOG4105C03	ribonuclease
APZ19_05590	ENOG4105EI2	Pseudouridine synthase
APZ19_05595	ENOG4108UHJ	MAF-like protein
APZ19_05600	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
APZ19_05605	ENOG4105VGS	50s ribosomal protein l32
APZ19_05610	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
APZ19_05615	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APZ19_05620	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
APZ19_05625	ENOG4105CHR	reductase
APZ19_05630	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APZ19_05635	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
APZ19_05645	ENOG4105HHA	aminodeoxychorismate lyase
APZ19_05650	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
APZ19_05655	ENOG4107QRG	dna polymerase iii
APZ19_05660	ENOG4105F8V	Hydrolase, tatD family
APZ19_05665	ENOG4105CI1	PTS System
APZ19_05680	ENOG4105C8J	)-transporter
APZ19_05695	ENOG4108NRW	Phospholipase, patatin family
APZ19_05700	ENOG4105CA9	Pyruvate kinase
APZ19_05705	ENOG4105DAG	ROK family
APZ19_05710	ENOG4107R88	Chemotaxis protein (CheV)
APZ19_05715	ENOG4105C0B	DNA polymerase III (alpha subunit)
APZ19_05730	ENOG4105UBK	short-chain dehydrogenase reductase
APZ19_05735	ENOG4105ERU	peptidase
APZ19_05745	ENOG4105CAT	Cytidine monophosphate kinase
APZ19_05750	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
APZ19_05755	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
APZ19_05760	ENOG4105Q4A	inner membrane protein yciS
APZ19_05765	ENOG4105CFV	Tetratricopeptide repeat protein
APZ19_05770	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
APZ19_05775	ENOG4108J59	Extracellular solute-binding protein, family 5
APZ19_05835	ENOG4105ENH	Sulfatase
APZ19_05840	ENOG4108WUH	Transcriptional regulator, TetR family
APZ19_05845	ENOG4108Q2G	(LipO)protein
APZ19_05850	ENOG4105DY2	Paraquat-inducible protein b
APZ19_05855	ENOG4105F1S	paraquat-inducible protein a
APZ19_05860	ENOG41060NJ	transcriptional regulator
APZ19_05865	ENOG4105NQN	cytochrome C
APZ19_05870	ENOG41090Y2	cytochrome C
APZ19_05875	ENOG4105DB1	molybdopterin oxidoreductase
APZ19_05880	ENOG4106WHD	Tetrathionate reductase
APZ19_05885	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
APZ19_05890	ENOG4106AFQ	Histidine kinase
APZ19_05895	ENOG4108ZXC	Two component transcriptional regulator, luxr family
APZ19_05910	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
APZ19_05920	ENOG4105CT4	transporter
APZ19_05925	ENOG4105DHT	Metal Dependent Phosphohydrolase
APZ19_05930	ENOG4105JQN	Transcriptional regulator
APZ19_05940	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
APZ19_05945	ENOG4105N6Y	Thioredoxin
APZ19_05955	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
APZ19_05965	ENOG4108MK9	spermidine N(1)-acetyltransferase
APZ19_05975	ENOG41080VW	acetyltransferase
APZ19_06015	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
APZ19_06025	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APZ19_06030	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APZ19_06035	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
APZ19_06045	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
APZ19_06060	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
APZ19_06070	ENOG4105J12	Multidrug resistance protein mdtN
APZ19_06075	ENOG4105EQ2	LysR family Transcriptional regulator
APZ19_06115	ENOG41062D9	Histidine kinase
APZ19_06120	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APZ19_06130	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
APZ19_06140	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_06145	ENOG4105WWK	YheO domain protein
APZ19_06150	ENOG4105KME	endoribonuclease L-psp
APZ19_06155	ENOG4107R6U	sodium dicarboxylate symporter
APZ19_06160	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
APZ19_06180	ENOG4105CCT	upf0313 protein
APZ19_06200	ENOG4105DZ2	Transcriptional regulator
APZ19_06205	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
APZ19_06215	ENOG4105K9H	YciI-like protein
APZ19_06220	ENOG4105NAU	thioesterase Superfamily protein
APZ19_06225	ENOG4107835	probably involved in intracellular septation (By similarity)
APZ19_06235	ENOG4105BZU	Histidine kinase
APZ19_06245	ENOG4105CK2	sodium dicarboxylate symporter
APZ19_06250	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
APZ19_06255	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
APZ19_06260	ENOG4105DK0	Indole-3-glycerol phosphate synthase
APZ19_06265	ENOG4108I0Q	anthranilate phosphoribosyltransferase
APZ19_06270	ENOG4105DDQ	anthranilate synthase
APZ19_06275	ENOG4105CRQ	synthase (Component I)
APZ19_06285	ENOG4105DB7	PHP domain protein
APZ19_06290	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
APZ19_06300	ENOG4105FE9	pseudouridine synthase
APZ19_06305	ENOG4108W5H	UPF0263 protein
APZ19_06320	ENOG4105CQ2	DNA polymerase
APZ19_06325	ENOG4105WH1	Two component transcriptional regulator luxr family
APZ19_06330	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
APZ19_06370	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
APZ19_06395	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APZ19_06400	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APZ19_06405	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
APZ19_06410	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APZ19_06425	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
APZ19_06435	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
APZ19_06440	ENOG4105DVI	reductase, NrfD
APZ19_06445	ENOG4105DA4	cytochrome c-type biogenesis protein
APZ19_06450	ENOG4107QX9	Thiol disulfide interChange protein
APZ19_06455	ENOG4108DMF	Cytochrome C biogenesis protein
APZ19_06465	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
APZ19_06490	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
APZ19_06495	ENOG4105EAQ	(twin-arginine translocation) pathway signal
APZ19_06500	ENOG4105C5X	domain protein
APZ19_06515	ENOG4105CH5	extracellular solute-binding protein, family 7
APZ19_06525	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
APZ19_06540	ENOG41067TZ	transcriptional regulator, MarR family
APZ19_06545	ENOG4105C94	Transporter
APZ19_06550	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_06570	ENOG4105CGF	Aromatic amino acid aminotransferase
APZ19_06575	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
APZ19_06580	ENOG4107RUZ	Sss sodium solute transporter superfamily
APZ19_06590	ENOG4105ETE	Transcriptional regulator (LacI family
APZ19_06605	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APZ19_06620	ENOG4105C5S	asparaginyl-tRNA synthetase
APZ19_06625	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_06630	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
APZ19_06635	ENOG4105WH1	Two component transcriptional regulator luxr family
APZ19_06645	ENOG4105BZU	Histidine kinase
APZ19_06650	ENOG4105EJQ	L-serine dehydratase
APZ19_06655	ENOG4105C44	Serine transporter
APZ19_06670	ENOG4105BZU	Histidine kinase
APZ19_06675	ENOG4105CRQ	synthase (Component I)
APZ19_06690	ENOG4105CM6	amino acid regulated cytosolic protein
APZ19_06695	ENOG4106K28	UPF0283 membrane protein
APZ19_06705	ENOG4105D9U	N-acetyltransferase
APZ19_06890	ENOG4108MTT	Glutamate-rich protein grpB
APZ19_07290	ENOG4108R4U	Hnh endonuclease
APZ19_07440	ENOG4105KVH	Transcriptional regulator
APZ19_07450	ENOG4105EC3	peptidase S51, dipeptidase E
APZ19_07465	ENOG4107RJ1	sodium solute
APZ19_07480	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
APZ19_07490	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
APZ19_07495	ENOG4105ETE	Transcriptional regulator (LacI family
APZ19_07500	ENOG4105CNV	Aldolase
APZ19_07505	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
APZ19_07510	ENOG4105CHR	reductase
APZ19_07535	ENOG4107WJM	-acetyltransferase
APZ19_07540	ENOG4105C8P	)-transporter
APZ19_07545	ENOG4105BZU	Histidine kinase
APZ19_07550	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_07555	ENOG4105BZU	Histidine kinase
APZ19_07560	ENOG4105CPI	Metal Dependent Phosphohydrolase
APZ19_07565	ENOG410829K	Lysine exporter protein (Lyse ygga)
APZ19_07570	ENOG4105G0K	glycine radical enzyme YjjI family
APZ19_07575	ENOG41076CZ	activating enzyme
APZ19_07585	ENOG4105EE5	Membrane protein terC
APZ19_07595	ENOG4105DHT	Metal Dependent Phosphohydrolase
APZ19_07605	ENOG4105BZU	Histidine kinase
APZ19_07620	ENOG4105E0U	tyrosine-specific transport protein
APZ19_07640	ENOG4105BZ1	(ABC) transporter
APZ19_07645	ENOG4105BZ1	(ABC) transporter
APZ19_07660	ENOG4105CR8	Transcriptional regulator
APZ19_07685	ENOG4105CFG	Acts as a chaperone (By similarity)
APZ19_07690	ENOG4105CFG	Acts as a chaperone (By similarity)
APZ19_07700	ENOG4105BZU	Histidine kinase
APZ19_07725	ENOG4105D4Y	metalloprotease
APZ19_07735	ENOG4107QY8	reductase
APZ19_07740	ENOG4105QAX	Iron-sulfur
APZ19_07745	ENOG4107KGK	dmso reductase anchor subunit
APZ19_07750	ENOG4108NEM	leader-binding protein dmsD
APZ19_07760	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
APZ19_07765	ENOG4105CQ7	ATP-dependent helicase
APZ19_07790	ENOG41090FY	type IV pilus biogenesis stability protein PilW
APZ19_07795	ENOG4105CVG	Homoserine O-transsuccinylase
APZ19_07825	ENOG4105E5D	amino acid
APZ19_07830	ENOG4105N14	lysine exporter protein LysE YggA
APZ19_07835	ENOG4105CR8	Transcriptional regulator
APZ19_07840	ENOG4107S9F	NmrA family
APZ19_07845	ENOG4105EJC	lysr family transcriptional regulator
APZ19_07850	ENOG4105D1S	lipid A biosynthesis
APZ19_07855	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
APZ19_07865	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
APZ19_07880	ENOG4105CTD	carboxy-peptidase
APZ19_07885	ENOG410829K	Lysine exporter protein (Lyse ygga)
APZ19_07895	ENOG4107QMS	site-determining protein
APZ19_07915	ENOG4105BZG	amino acid carrier protein
APZ19_07935	ENOG41063TF	transcriptional regulator (AraC
APZ19_07970	ENOG4105CR8	Transcriptional regulator
APZ19_07975	ENOG4105E0M	Sulfatase
APZ19_07980	ENOG4105C8N	cysteinyl-tRNA synthetase
APZ19_07985	ENOG4107QI1	Mate efflux family protein
APZ19_07990	ENOG41080XQ	Signal transduction protein with cbs domains
APZ19_08000	ENOG4105C94	Transporter
APZ19_08005	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
APZ19_08010	ENOG4108JPW	Aminotransferase
APZ19_08015	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
APZ19_08020	ENOG4105CZK	Aspartate kinase
APZ19_08030	ENOG4105CV8	reductase
APZ19_08035	ENOG4105HEI	LysR family (Transcriptional regulator
APZ19_08040	ENOG4105CA0	peroxidase
APZ19_08045	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APZ19_08050	ENOG4105HEI	LysR family (Transcriptional regulator
APZ19_08070	ENOG4108K2B	transcriptional regulator
APZ19_08075	ENOG4108RNG	Permease of the drug metabolite transporter
APZ19_08080	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
APZ19_08085	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
APZ19_08100	ENOG4105CMR	udp-glucose 4-epimerase
APZ19_08120	ENOG4107V40	secretion protein, HlyD family
APZ19_08135	ENOG4105C87	Aminotransferase class I and II
APZ19_08140	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
APZ19_08145	ENOG4108V9W	transcriptional regulatory protein
APZ19_08150	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
APZ19_08155	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
APZ19_08160	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
APZ19_08190	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
APZ19_08195	ENOG4105C26	Dehydrogenase
APZ19_08200	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APZ19_08210	ENOG4105BZS	acriflavin resistance protein
APZ19_08220	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_08225	ENOG4105EJ9	Membrane
APZ19_08260	ENOG4108ESY	Metal dependent phosphohydrolase
APZ19_08265	ENOG4108ESY	Metal dependent phosphohydrolase
APZ19_08305	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APZ19_08360	ENOG4105CS6	Rhs element vgr protein
APZ19_08375	ENOG4105CR4	methylisocitrate lyase
APZ19_08380	ENOG4105BZN	citrate synthase
APZ19_08385	ENOG4108I0Z	Aconitate hydratase
APZ19_08390	ENOG4105C7F	AcnD-accessory protein PrpF
APZ19_08395	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
APZ19_08405	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
APZ19_08415	ENOG410667J	hydrolase
APZ19_08420	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
APZ19_08425	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
APZ19_08430	ENOG4105BZU	Histidine kinase
APZ19_08440	ENOG4105CDV	Ompa motb domain protein
APZ19_08470	ENOG4105DR4	Methyltransferase
APZ19_08475	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_08480	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
APZ19_08485	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
APZ19_08495	ENOG4108MN8	Membrane
APZ19_08500	ENOG4105CDA	abc transporter atp-binding protein
APZ19_08505	ENOG4105DRP	amino acid AbC transporter
APZ19_08510	ENOG4105EZ7	amino acid ABC transporter
APZ19_08515	ENOG4107QXX	ABC transporter
APZ19_08525	ENOG4108VPT	UPF0234 protein
APZ19_08530	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
APZ19_08550	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
APZ19_08555	ENOG4105DY2	Paraquat-inducible protein b
APZ19_08560	ENOG4105H2K	paraquat-inducible protein a
APZ19_08565	ENOG4105BZ1	(ABC) transporter
APZ19_08570	ENOG4108ZGC	gaf domain protein
APZ19_08575	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
APZ19_08580	ENOG4105CN1	protease
APZ19_08590	ENOG4105CD8	aminopeptidase N
APZ19_08600	ENOG4105C7I	Dehydrogenase
APZ19_08605	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
APZ19_08610	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
APZ19_08615	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
APZ19_08625	ENOG4105C5H	ABC transporter
APZ19_08640	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
APZ19_08645	ENOG4105DAN	ATP-dependent protease
APZ19_08650	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
APZ19_08675	ENOG4105BZU	Histidine kinase
APZ19_08690	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
APZ19_08705	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
APZ19_08715	ENOG4105C59	p-type ATPase
APZ19_08730	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
APZ19_08735	ENOG4105Q9Y	Universal stress protein
APZ19_08740	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
APZ19_08760	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
APZ19_08765	ENOG4105F38	ABC transporter, permease
APZ19_08770	ENOG4105D38	putrescine abc transporter
APZ19_08775	ENOG4107RUE	extracellular solute-binding protein family 1
APZ19_08780	ENOG4107RUE	extracellular solute-binding protein family 1
APZ19_08785	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
APZ19_08800	ENOG4105QAX	Iron-sulfur
APZ19_08805	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
APZ19_08815	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
APZ19_08835	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
APZ19_08840	ENOG4105C5H	ABC transporter
APZ19_08860	ENOG4105BZU	Histidine kinase
APZ19_08865	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_08875	ENOG4107A5B	Binding-protein-dependent transport systems, inner membrane component
APZ19_08880	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
APZ19_08885	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
APZ19_08890	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
APZ19_08905	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
APZ19_08910	ENOG4106IUH	DTW domain containing protein
APZ19_08955	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_08960	ENOG4107TT5	NLP P60 protein
APZ19_08970	ENOG4105BZU	Histidine kinase
APZ19_08975	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
APZ19_08980	ENOG4105FGM	Fructosamine kinase
APZ19_08990	ENOG4108R6K	riboflavin synthase, subunit alpha
APZ19_08995	ENOG4107QI1	Mate efflux family protein
APZ19_09010	ENOG41082AN	stage II sporulation protein
APZ19_09015	ENOG4107QKZ	Ompa motb domain protein
APZ19_09020	ENOG4107V1M	polysaccharide export protein
APZ19_09035	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_09045	ENOG4107TAE	Glycosyl transferase (Group 1
APZ19_09085	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
APZ19_09090	ENOG4105CND	Glycosyl transferase, family 2
APZ19_09105	ENOG4105F88	accessory colonization factor AcfD
APZ19_09130	ENOG4105BZU	Histidine kinase
APZ19_09135	ENOG4105BZU	Histidine kinase
APZ19_09155	ENOG4108UW5	maltose o-acetyltransferase
APZ19_09160	ENOG4105BZU	Histidine kinase
APZ19_09325	ENOG4108E1C	hydrolase
APZ19_09385	ENOG4106V8H	Nucleoid-associated protein
APZ19_09415	ENOG4108WTW	DNA transposition protein
APZ19_09440	ENOG4108ZT1	Transcriptional regulator
APZ19_09455	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
APZ19_09460	ENOG4108YK4	Acid-resistance membrane protein
APZ19_09465	ENOG4105CUY	Mechanosensitive ion channel
APZ19_09475	ENOG4108MA4	Peptidase M66
APZ19_09480	ENOG4107QHE	Choloylglycine hydrolase
APZ19_09495	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APZ19_09555	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
APZ19_09560	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APZ19_09565	ENOG4105Q9Y	Universal stress protein
APZ19_09580	ENOG4105C0A	alcohol dehydrogenase
APZ19_09585	ENOG4107W7X	Aldolase
APZ19_09590	ENOG4105NWF	RbsD or FucU transport
APZ19_09595	ENOG4105CMG	Carbohydrate kinase
APZ19_09605	ENOG4105EDR	glucose galactose transporter
APZ19_09610	ENOG4107EDW	L-fucose operon activator
APZ19_09625	ENOG4108WQH	regulatoR
APZ19_09640	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
APZ19_09645	ENOG4105YGP	holo-ACP synthase CitX
APZ19_09650	ENOG4105CHY	citrate lyase, alpha
APZ19_09655	ENOG4105CI0	Citrate lyase
APZ19_09660	ENOG4105XGS	Covalent carrier of the coenzyme of citrate lyase (By similarity)
APZ19_09665	ENOG4105DUA	(citrate (pro-3S)-lyase ligase
APZ19_09680	ENOG4107QSA	Oxaloacetate decarboxylase
APZ19_09685	ENOG4105D9Q	decarboxylase (Beta subunit)
APZ19_09690	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
APZ19_09695	ENOG4106YYS	transcriptional regulatory protein
APZ19_09730	ENOG4108RXX	maleylacetoacetate isomerase
APZ19_09740	ENOG4105F1J	Homogentisate 1,2-dioxygenase
APZ19_09745	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
APZ19_09755	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
APZ19_09765	ENOG4105BZU	Histidine kinase
APZ19_09770	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
APZ19_09775	ENOG4108VKG	metal-dependent hydrolase
APZ19_09780	ENOG4108VAU	general secretion pathway protein G
APZ19_09805	ENOG4105F04	LysR family Transcriptional regulator
APZ19_09830	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
APZ19_09835	ENOG4108IU2	vtamin B12-transporter permease
APZ19_09840	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
APZ19_09850	ENOG4108TGR	phosphatase
APZ19_09860	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
APZ19_09865	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
APZ19_09870	ENOG4107XWI	flavin reductase domain protein, FMN-binding
APZ19_09875	ENOG4105K4T	epimerase
APZ19_09880	ENOG4108ETY	sodium dicarboxylate symporter
APZ19_09890	ENOG4105CJB	Exodeoxyribonuclease I
APZ19_09895	ENOG4105VAW	lrga family
APZ19_09900	ENOG41067MG	lrgb family
APZ19_09905	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
APZ19_09915	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
APZ19_09920	ENOG4105FQ6	thiopurine methyltransferase
APZ19_09930	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
APZ19_09940	ENOG4105WBN	Transcriptional regulator (LacI family
APZ19_09945	ENOG4105D7K	pfkb domain protein
APZ19_09950	ENOG4107R3K	hydrolase
APZ19_09960	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
APZ19_09965	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
APZ19_09970	ENOG4108KHP	Diguanylate cyclase
APZ19_10000	ENOG4105K8R	UPF0145 protein
APZ19_10005	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
APZ19_10010	ENOG4105KME	endoribonuclease L-psp
APZ19_10025	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
APZ19_10030	ENOG41082NX	50s ribosomal protein l35
APZ19_10035	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
APZ19_10040	ENOG4105C22	threonyL-tRNA synthetase
APZ19_10055	ENOG4105CZE	histidine utilization repressor
APZ19_10060	ENOG4105CI2	imidazolone-5-propionate hydrolase
APZ19_10065	ENOG41088SP	formiminoglutamate hydrolase
APZ19_10070	ENOG4105CGP	Urocanate hydratase
APZ19_10075	ENOG4105C84	Histidine ammonia-lyase
APZ19_10090	ENOG4105CQB	FAD linked oxidase domain protein
APZ19_10105	ENOG4105CDV	Ompa motb domain protein
APZ19_10130	ENOG4105C8V	SAICAR synthetase
APZ19_10145	ENOG4105HDD	phospholipase
APZ19_10150	ENOG4105CQ7	ATP-dependent helicase
APZ19_10155	ENOG4107R1I	NAD-dependent malic enzyme
APZ19_10160	ENOG4107GZ4	SanA protein
APZ19_10165	ENOG4105C8P	)-transporter
APZ19_10170	ENOG4105BZU	Histidine kinase
APZ19_10190	ENOG4105C3M	thioredoxin reductase
APZ19_10195	ENOG4108JJ9	ABC, transporter
APZ19_10200	ENOG4108JJ8	(ABC) transporter
APZ19_10205	ENOG4105BZC	d-serine deaminase
APZ19_10210	ENOG4105W8I	Transcriptional regulator
APZ19_10215	ENOG4105BZU	Histidine kinase
APZ19_10245	ENOG4105BZU	Histidine kinase
APZ19_10255	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
APZ19_10265	ENOG4105BZU	Histidine kinase
APZ19_10295	ENOG4105DWU	Membrane
APZ19_10305	ENOG4105DY8	decarboxylase
APZ19_10310	ENOG4106KNT	transcriptional regulator
APZ19_10320	ENOG41090BQ	Glutaredoxin
APZ19_10325	ENOG4105D0C	transport protein
APZ19_10330	ENOG4105RKW	reductase (By
APZ19_10335	ENOG4107QPN	acyl-Coa dehydrogenase
APZ19_10340	ENOG41067SE	Tetr family transcriptional regulator
APZ19_10345	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
APZ19_10360	ENOG4108I0Y	(ABC) transporter
APZ19_10365	ENOG4107QI1	Mate efflux family protein
APZ19_10370	ENOG4105CGD	Nad-dependent epimerase dehydratase
APZ19_10375	ENOG4108NRW	Phospholipase, patatin family
APZ19_10385	ENOG4105C2C	drug resistance transporter, Bcr CflA
APZ19_10390	ENOG4105I08	Pseudouridine synthase
APZ19_10395	ENOG4105CFI	type iii restriction protein res subunit
APZ19_10400	ENOG4108KHP	Diguanylate cyclase
APZ19_10410	ENOG4105ETX	regulatoR
APZ19_10415	ENOG4105EB3	Histidine kinase
APZ19_10430	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
APZ19_10445	ENOG4105CGH	5'-nucleotidase
APZ19_10455	ENOG4105XZD	Fe-S protein
APZ19_10465	ENOG4105CHH	sulfate transporter
APZ19_10475	ENOG4108ZXC	Two component transcriptional regulator, luxr family
APZ19_10480	ENOG4106AFQ	Histidine kinase
APZ19_10490	ENOG4105BZ8	glutamate synthase
APZ19_10500	ENOG4108RSN	SNARE associated Golgi
APZ19_10505	ENOG4105VNH	ABC transporter solute-binding protein
APZ19_10510	ENOG4105CXZ	ABC transporter, permease
APZ19_10515	ENOG4108VGW	abc transporter atp-binding protein
APZ19_10520	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
APZ19_10525	ENOG4108JUA	Transcriptional regulator
APZ19_10530	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
APZ19_10535	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
APZ19_10550	ENOG4108W1A	pseudouridine synthase
APZ19_10560	ENOG4105C8J	)-transporter
APZ19_10570	ENOG4105C28	cystathionine
APZ19_10575	ENOG4107IFA	Lipase (EC 3.1.1.3)
APZ19_10585	ENOG4108R3E	Dna-3-methyladenine glycosylase i
APZ19_10605	ENOG4105FM1	phage shock protein C
APZ19_10610	ENOG4105YYT	phage shock protein B
APZ19_10615	ENOG41087YS	Phage shock protein A
APZ19_10620	ENOG4105E51	psp operon transcriptional activator
APZ19_10625	ENOG4108J59	Extracellular solute-binding protein, family 5
APZ19_10630	ENOG4108I5W	peptide transport system, permease protein
APZ19_10635	ENOG4108EU3	peptide transport system, permease
APZ19_10640	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
APZ19_10645	ENOG4108JQ2	peptide transport system atp-binding protein
APZ19_10655	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
APZ19_10670	ENOG4108J2R	molybdopterin oxidoreductase
APZ19_10690	ENOG4105TMB	Formate nitrite transporter
APZ19_10715	ENOG4105GFG	DUF218 domain
APZ19_10720	ENOG4107104	thymidine kinase
APZ19_10725	ENOG4105C8N	cysteinyl-tRNA synthetase
APZ19_10730	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
APZ19_10735	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
APZ19_10740	ENOG4105D58	Diguanylate phosphodiesterase
APZ19_10745	ENOG4105K5B	UPF0225 protein
APZ19_10775	ENOG4105CIH	Imidazole acetol-phosphate transaminase
APZ19_10780	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
APZ19_10785	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
APZ19_10790	ENOG4107S6Z	Na H antiporter
APZ19_10795	ENOG4108YX2	DNA-binding protein
APZ19_10800	ENOG4107RE1	Inosine-guanosine kinase
APZ19_10810	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
APZ19_10815	ENOG41075W9	High frequency lysogenization protein HflD homolog
APZ19_10820	ENOG4107QTF	adenylosuccinate lyase
APZ19_10830	ENOG4105RHG	
APZ19_10840	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
APZ19_10855	ENOG4107FW0	short-chain dehydrogenase reductase
APZ19_10865	ENOG4105D0M	Protease HtpX homolog
APZ19_10875	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
APZ19_10885	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APZ19_10890	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
APZ19_10895	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
APZ19_10900	ENOG4105KSC	Transcriptional regulator, TraR DksA family
APZ19_10910	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
APZ19_10915	ENOG4105D1H	recombination factor protein RarA
APZ19_10920	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
APZ19_10925	ENOG4105CNU	cell division protein FtsK
APZ19_10930	ENOG4105EW9	transcriptional regulator AsnC family
APZ19_10935	ENOG4105DCF	alanine dehydrogenase
APZ19_10945	ENOG4107R11	Transcriptional regulator
APZ19_10955	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
APZ19_10965	ENOG4108UHU	Aldolase
APZ19_10970	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
APZ19_10975	ENOG4105M5J	Cupin 2, conserved barrel domain protein
APZ19_10980	ENOG4105EY3	heparinase II III family protein
APZ19_10985	ENOG4105EY3	heparinase II III family protein
APZ19_11005	ENOG4107QUY	Guanine deaminase
APZ19_11030	ENOG4105KXC	Collagenase
APZ19_11065	ENOG4108PJD	permease
APZ19_11085	ENOG4105CHR	reductase
APZ19_11090	ENOG4105M5J	Cupin 2, conserved barrel domain protein
APZ19_11100	ENOG4107RJ1	sodium solute
APZ19_11105	ENOG4105D2H	Uronic isomerase
APZ19_11130	ENOG4107EJG	GntR family transcriptional regulator
APZ19_11135	ENOG4105CHR	reductase
APZ19_11140	ENOG4107EJG	GntR family transcriptional regulator
APZ19_11145	ENOG41080XP	Cbs domain
APZ19_11150	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
APZ19_11160	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
APZ19_11175	ENOG4107RJ1	sodium solute
APZ19_11195	ENOG4105E0A	ABC, transporter
APZ19_11200	ENOG4108U1V	ABC transporter, permease
APZ19_11205	ENOG4108IHU	transport system permease protein
APZ19_11235	ENOG4105JXH	GntR family transcriptional regulator
APZ19_11245	ENOG4105BZS	acriflavin resistance protein
APZ19_11250	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
APZ19_11260	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_11275	ENOG4105DEF	Extracellular solute-binding protein, family 5
APZ19_11280	ENOG4108JQ7	(ABC) transporter
APZ19_11285	ENOG4105C3U	ABC transporter
APZ19_11290	ENOG4107R73	Mate efflux family protein
APZ19_11315	ENOG4105IJJ	transcriptional regulator, crp fnr family
APZ19_11320	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
APZ19_11325	ENOG4105CS2	ec 3.2.1.21
APZ19_11330	ENOG4105C5Y	PTS System
APZ19_11345	ENOG4105ENH	Sulfatase
APZ19_11405	ENOG4105C9U	ATP-dependent DNA helicase RecQ
APZ19_11410	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
APZ19_11415	ENOG4105EUJ	GTP cyclohydrolase i
APZ19_11420	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
APZ19_11425	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
APZ19_11470	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
APZ19_11495	ENOG4108RNS	Exports L-alanine (By similarity)
APZ19_11500	ENOG4105BZU	Histidine kinase
APZ19_11510	ENOG4106032	Glutathionylspermidine synthase
APZ19_11520	ENOG4105Z6B	inner membrane protein yjfl
APZ19_11530	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
APZ19_11535	ENOG4105UFD	tol-pal system protein YbgF
APZ19_11540	ENOG4105KCK	Peptidoglycan-associated lipoprotein
APZ19_11545	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
APZ19_11555	ENOG4105M8F	Biopolymer transport protein exbD tolR
APZ19_11560	ENOG4105E02	MotA TolQ exbB proton channel
APZ19_11565	ENOG4107YD3	Thioesterase
APZ19_11580	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APZ19_11585	ENOG4105C4M	(Ubiquinol oxidase) subunit I
APZ19_11590	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
APZ19_11595	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
APZ19_11600	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_11605	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
APZ19_11610	ENOG4105C9M	aspartyl-trna synthetase
APZ19_11615	ENOG41081XQ	Conserved Protein
APZ19_11620	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
APZ19_11625	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
APZ19_11635	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
APZ19_11660	ENOG4105CEY	Amp-dependent synthetase and ligase
APZ19_11665	ENOG4107RGH	Aldehyde dehydrogenase
APZ19_11670	ENOG4108ZX5	transcriptional regulator
APZ19_11675	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
APZ19_11680	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
APZ19_11685	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
APZ19_11690	ENOG4106371	Methyltransferase
APZ19_11695	ENOG4107S90	membrAne
APZ19_11700	ENOG4106WF9	DNA-binding transcriptional regulator TorR
APZ19_11705	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
APZ19_11715	ENOG4105ETE	Transcriptional regulator (LacI family
APZ19_11720	ENOG4105HP8	regulator of competence-specific genes
APZ19_11740	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
APZ19_11745	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
APZ19_11750	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
APZ19_11755	ENOG4105RKX	Protein of unknown function (DUF2498)
APZ19_11760	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
APZ19_11770	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
APZ19_11775	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
APZ19_11780	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
APZ19_11785	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APZ19_11790	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
APZ19_11795	ENOG4105VEQ	Cold shock protein
APZ19_11805	ENOG4108R99	pseudouridine synthase
APZ19_11820	ENOG4105DVT	helicase
APZ19_11825	ENOG4105EJ9	Membrane
APZ19_11830	ENOG4108URS	primosomal replication protein n''
APZ19_11835	ENOG4106428	Protein of unknown function (DUF2496)
APZ19_11840	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_11845	ENOG4105CGK	Exodeoxyribonuclease III
APZ19_11850	ENOG4108JJ6	Type I secretion system ATPase
APZ19_11870	ENOG4105DSP	amino acid AbC transporter
APZ19_11875	ENOG4105E89	ABC transporter
APZ19_11880	ENOG4108JEH	abc transporter atp-binding protein
APZ19_11895	ENOG4105C6N	Formate acetyltransferase
APZ19_11905	ENOG4105F1A	Pyruvate formate-lyase
APZ19_11915	ENOG4105XWI	UPF0304 protein
APZ19_11920	ENOG4105CYN	Serine protein kinase
APZ19_11925	ENOG4106AKX	UPF0229 protein
APZ19_11930	ENOG4105ED1	spovr family
APZ19_11935	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
APZ19_11940	ENOG4105W49	UPF0434 protein
APZ19_11945	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
APZ19_11950	ENOG4105BZ1	(ABC) transporter
APZ19_11955	ENOG4108EC8	DNA internalization-related competence protein ComEC
APZ19_11965	ENOG4105D60	lipoprotein releasing system transmembrane protein
APZ19_11970	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APZ19_11975	ENOG4105D60	lipoprotein releasing system transmembrane protein
APZ19_11985	ENOG4108JA2	transcriptioN-repair coupling factor
APZ19_12000	ENOG4105CEP	NADH dehydrogenase
APZ19_12005	ENOG4105D0Y	UPF0227 protein
APZ19_12030	ENOG4105K59	histidine triad (HIT) protein
APZ19_12035	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_12045	ENOG4107SXA	Phosphorylase
APZ19_12060	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APZ19_12065	ENOG4105DZ0	fad dependent oxidoreductase
APZ19_12070	ENOG4108Z4U	Ferredoxin
APZ19_12100	ENOG410890F	Dynamin family
APZ19_12130	ENOG4108KHX	Diguanylate cyclase
APZ19_12145	ENOG4108MNP	Glycoprotein polysaccharide metabolism
APZ19_12150	ENOG4105C29	acyl-CoA thioesterase
APZ19_12160	ENOG4108XM1	transcriptional regulator AsnC family
APZ19_12180	ENOG4105BZS	acriflavin resistance protein
APZ19_12225	ENOG4105HMI	Membrane
APZ19_12235	ENOG4105ETT	transcriptional Regulator, LysR family
APZ19_12240	ENOG4105CI1	PTS System
APZ19_12245	ENOG4105CEY	Amp-dependent synthetase and ligase
APZ19_12250	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
APZ19_12255	ENOG4108IPT	Naphthoate synthase
APZ19_12260	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
APZ19_12265	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
APZ19_12270	ENOG4105E4F	Isochorismate synthase
APZ19_12275	ENOG4105CHM	Aminotransferase
APZ19_12280	ENOG4105DK2	UPF0207 protein
APZ19_12285	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
APZ19_12300	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
APZ19_12305	ENOG4105EIN	peptidylprolyl cis-trans isomerase
APZ19_12310	ENOG4105K70	DNA-binding protein
APZ19_12315	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
APZ19_12320	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
APZ19_12325	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
APZ19_12330	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
APZ19_12335	ENOG4105CQZ	Histidine kinase
APZ19_12340	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_12345	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
APZ19_12350	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
APZ19_12355	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
APZ19_12360	ENOG4105CNG	UPF0061 protein
APZ19_12380	ENOG4107ZYR	domain protein
APZ19_12385	ENOG4105C94	Transporter
APZ19_12390	ENOG4105C1J	atp-dependent rna helicase
APZ19_12400	ENOG4105D05	Receptor
APZ19_12415	ENOG4105CEY	Amp-dependent synthetase and ligase
APZ19_12415	ENOG4105CEY	Amp-dependent synthetase and ligase
APZ19_12420	ENOG4105WQI	isochorismatase
APZ19_12425	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
APZ19_12430	ENOG4105E4F	Isochorismate synthase
APZ19_12440	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
APZ19_12485	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
APZ19_12505	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
APZ19_12510	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
APZ19_12515	ENOG4105C84	Histidine ammonia-lyase
APZ19_12550	ENOG4105C2D	reductase
APZ19_12555	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
APZ19_12570	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
APZ19_12575	ENOG4105D9N	nucleoside
APZ19_12580	ENOG4105EQ2	LysR family Transcriptional regulator
APZ19_12585	ENOG4105CVE	Lytic murein transglycosylase
APZ19_12590	ENOG4105VNG	YcgL domain-containing protein
APZ19_12595	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
APZ19_12600	ENOG4107QMS	site-determining protein
APZ19_12605	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
APZ19_12610	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
APZ19_12615	ENOG4105CEY	Amp-dependent synthetase and ligase
APZ19_12620	ENOG410832A	alpha/beta hydrolase fold
APZ19_12625	ENOG4105R8X	Outer membrane lipoprotein Slp
APZ19_12635	ENOG41072GX	Peptidase M22 Glycoprotease
APZ19_12640	ENOG4105DVT	helicase
APZ19_12645	ENOG4105CIY	formyltetrahydrofolate deformylase
APZ19_12650	ENOG4106ZCM	YecM protein
APZ19_12660	ENOG4105C75	arginyL-tRNA synthetase
APZ19_12680	ENOG4105XFK	Ferrous iron transport protein A
APZ19_12685	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
APZ19_12690	ENOG4105NXV	High-affinity zinc uptake system protein
APZ19_12695	ENOG4105FDK	ABC transporter
APZ19_12700	ENOG4105FAV	ABC, transporter
APZ19_12705	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
APZ19_12710	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
APZ19_12715	ENOG4105C7S	Dehydrogenase
APZ19_12720	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
APZ19_12725	ENOG4105E33	succinate dehydrogenase
APZ19_12730	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
APZ19_12735	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
APZ19_12740	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
APZ19_12745	ENOG4105BZN	citrate synthase
APZ19_12750	ENOG4107QNR	UPF0135 protein
APZ19_12760	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
APZ19_12765	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
APZ19_12770	ENOG4105EV9	Alpha Beta Hydrolase
APZ19_12780	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
APZ19_12790	ENOG41090R7	Ferric uptake
APZ19_12795	ENOG4105X0D	Fimbrial protein
APZ19_12800	ENOG4105CX6	glutaminyL-tRNA synthetase
APZ19_12805	ENOG4105CI1	PTS System
APZ19_12815	ENOG4105CE4	GlcNAc 6-P deacetylase
APZ19_12820	ENOG4105E2R	ROK family
APZ19_12825	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
APZ19_12830	ENOG4105CAQ	asparagine synthetase
APZ19_12835	ENOG4105MDZ	Transcriptional activator rfaH
APZ19_12840	ENOG4105DUX	Transporter
APZ19_12845	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
APZ19_12850	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
APZ19_12855	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
APZ19_12860	ENOG4108DQ1	activator toxR
APZ19_12880	ENOG4108RE9	Phosphodiesterase
APZ19_12910	ENOG4105ECP	epimerase
APZ19_12915	ENOG4105E1F	short-chain dehydrogenase reductase
APZ19_12925	ENOG4107QR8	Thioredoxin
APZ19_12935	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
APZ19_12940	ENOG4107EEX	Cellulose synthase regulator protein
APZ19_12945	ENOG4107QZ7	Cellulose synthase catalytic subunit
APZ19_12965	ENOG4105D1V	cellulose synthase operon protein YhjU
APZ19_12970	ENOG4107QX8	SPFH domain, Band 7 family protein
APZ19_12995	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
APZ19_13005	ENOG4105EXN	Sulfate transport protein CysZ
APZ19_13010	ENOG4105C6T	cysteine synthase
APZ19_13020	ENOG4105KZ7	phosphocarrier protein hpr
APZ19_13025	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
APZ19_13030	ENOG4105C5Y	PTS System
APZ19_13040	ENOG4105I03	Flagellin
APZ19_13045	ENOG4105I03	Flagellin
APZ19_13060	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
APZ19_13065	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
APZ19_13070	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
APZ19_13075	ENOG4105CGA	flagellar basal-body rod protein FlgG
APZ19_13080	ENOG4108KPB	Flagellar basal-body rod protein FlgF
APZ19_13085	ENOG4105BZE	flagellar hook protein, FlgE
APZ19_13090	ENOG4105W00	Flagellar hook capping protein
APZ19_13095	ENOG4108ZC9	flagellar basal-body rod protein flgc
APZ19_13100	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
APZ19_13105	ENOG4105BZU	Histidine kinase
APZ19_13110	ENOG4107R88	Chemotaxis protein (CheV)
APZ19_13155	ENOG4105UYK	outer membrane protein a
APZ19_13160	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
APZ19_13170	ENOG41081QG	Porin Gram-negative type
APZ19_13180	ENOG4105C59	p-type ATPase
APZ19_13195	ENOG4105E2D	ec 3.2.1.52
APZ19_13215	ENOG4108DG9	Smr protein MutS2
APZ19_13220	ENOG4105FE9	pseudouridine synthase
APZ19_13225	ENOG4108Z66	YbaK ebsC protein
APZ19_13230	ENOG4105CGH	5'-nucleotidase
APZ19_13235	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
APZ19_13240	ENOG41063JG	Transcriptional regulator
APZ19_13245	ENOG4108YY7	Invasion gene expression up-regulator SirB
APZ19_13250	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
APZ19_13255	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
APZ19_13260	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
APZ19_13270	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
APZ19_13275	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
APZ19_13280	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
APZ19_13285	ENOG4105C3G	gtp-binding protein
APZ19_13395	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
APZ19_13405	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
APZ19_13410	ENOG4105C9A	Phoh family
APZ19_13415	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
APZ19_13420	ENOG4108JU5	Magnesium and cobalt efflux protein
APZ19_13425	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
APZ19_13430	ENOG4107PAI	alpha helical protein
APZ19_13435	ENOG4105C8T	Leucyl-tRNA synthetase
APZ19_13440	ENOG4108U2H	Rare lipoprotein B
APZ19_13445	ENOG4105DJF	DNA polymerase III, delta' subunit
APZ19_13450	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
APZ19_13455	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
APZ19_13460	ENOG4105CJN	penicillin-binding protein
APZ19_13465	ENOG4105CNI	cell division protein FtsW
APZ19_13470	ENOG4105K6T	rare lipoprotein A
APZ19_13475	ENOG4105DZ1	carboxypeptidase
APZ19_13480	ENOG4108Z43	UPF0250 protein
APZ19_13485	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
APZ19_13490	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
APZ19_13495	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
APZ19_13500	ENOG4108JYZ	YitT family
APZ19_13515	ENOG4105CG3	alpha amylase, catalytic region
APZ19_13520	ENOG4105C5Y	PTS System
APZ19_13525	ENOG4105D4X	repressor
APZ19_13530	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
APZ19_13535	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
APZ19_13540	ENOG4108UMI	ABC transporter, permease
APZ19_13545	ENOG4105D01	(LipO)protein
APZ19_13555	ENOG4105CGH	5'-nucleotidase
APZ19_13560	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
APZ19_13565	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
APZ19_13570	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
APZ19_13580	ENOG4105BZU	Histidine kinase
APZ19_13585	ENOG4105EWT	decarboxylase family
APZ19_13590	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
APZ19_13595	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
APZ19_13600	ENOG4105M08	Membrane
APZ19_13610	ENOG4105ETT	transcriptional Regulator, LysR family
APZ19_13615	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
APZ19_13620	ENOG4106VK6	Flagellar motor protein
APZ19_13620	ENOG4106VK6	Flagellar motor protein
APZ19_13625	ENOG4105E14	MotA TolQ exbB proton channel
APZ19_13630	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
APZ19_13635	ENOG4105CTB	Polyprenyl synthetase
APZ19_13640	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
APZ19_13645	ENOG4108ZAI	phosphatidylglycerophosphatase a
APZ19_13650	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
APZ19_13655	ENOG4107YIM	Involved in the transcription termination process (By similarity)
APZ19_13660	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
APZ19_13675	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
APZ19_13680	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
APZ19_13685	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
APZ19_13690	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
APZ19_13695	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
APZ19_13700	ENOG4108DJV	Fermentation respiration switch protein
APZ19_13705	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
APZ19_13710	ENOG4105C7N	Xanthine uracil vitamin C permease
APZ19_13715	ENOG4105CIN	aminoacyl-histidine dipeptidase
APZ19_13745	ENOG4108ETH	Formylglycinamide ribotide synthetase
APZ19_13755	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
APZ19_13765	ENOG4108Z6B	deaminase
APZ19_13770	ENOG4105CFC	Transporter
APZ19_13805	ENOG4105CFG	Acts as a chaperone (By similarity)
APZ19_13820	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
APZ19_13825	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
APZ19_13835	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
APZ19_13840	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
APZ19_13845	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
APZ19_13855	ENOG4105VDB	UPF0125 protein
APZ19_13860	ENOG4108Z1B	Cyclase dehydrase
APZ19_13865	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
APZ19_13875	ENOG4105ETT	transcriptional Regulator, LysR family
APZ19_13880	ENOG410613R	integral membrane protein, YccS YhfK family
APZ19_13900	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
APZ19_13905	ENOG4108IQK	o-acetylhomoserine
APZ19_13910	ENOG4105D64	Mechanosensitive ion channel
APZ19_13925	ENOG410825D	TRANSCRIPTIONal REGULATOR, LysR family
APZ19_13930	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
APZ19_13935	ENOG4105BZG	amino acid carrier protein
APZ19_13940	ENOG4106HK8	GPR1 FUN34 yaaH family protein
APZ19_13950	ENOG4107S6Z	Na H antiporter
APZ19_13955	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
APZ19_13960	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APZ19_13965	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
APZ19_13975	ENOG410620I	Diguanylate cyclase
APZ19_13985	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
APZ19_13990	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
APZ19_13995	ENOG4105N21	Membrane
APZ19_14000	ENOG4105CUT	histidyl-tRNA synthetase
APZ19_14005	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
APZ19_14015	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
APZ19_14020	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
APZ19_14025	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
APZ19_14030	ENOG4105WVQ	Fe-S assembly protein IscX
APZ19_14035	ENOG4108ZIT	Ferredoxin, 2FE-2S
APZ19_14040	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
APZ19_14045	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
APZ19_14050	ENOG4108Z4V	iron-sulfur cluster assembly
APZ19_14055	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
APZ19_14060	ENOG4105C3J	Cysteine desulfurase
APZ19_14065	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
APZ19_14070	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
APZ19_14075	ENOG4105ECY	inositol monophosphatase
APZ19_14080	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APZ19_14085	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APZ19_14090	ENOG4105VIE	preprotein translocase, subunit YajC
APZ19_14095	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
APZ19_14100	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
APZ19_14115	ENOG4105W87	Cbs domain
APZ19_14120	ENOG4108I9X	Isocitrate lyase
APZ19_14125	ENOG4107QP3	malate synthase g
APZ19_14130	ENOG4105C5Q	Transcriptional regulator
APZ19_14135	ENOG4105D3R	alkyl hydroperoxide reductase
APZ19_14140	ENOG4106N3A	copper homeostasis protein cutc
APZ19_14145	ENOG4105CSR	polyphosphate kinase 2
APZ19_14170	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
APZ19_14175	ENOG4105E2Z	phosphate ABC transporter (Permease
APZ19_14180	ENOG4105C8U	phosphate abc transporter
APZ19_14185	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
APZ19_14190	ENOG4105C9X	ppx gppa phosphatase
APZ19_14200	ENOG4105BZU	Histidine kinase
APZ19_14205	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APZ19_14210	ENOG4105DH7	May be involved in recombination (By similarity)
APZ19_14215	ENOG4105CFP	Peptidase U32
APZ19_14220	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
APZ19_14280	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APZ19_14285	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
APZ19_14290	ENOG4105C34	Pseudouridine synthase
APZ19_14295	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APZ19_14300	ENOG4105E4C	Lytic transglycosylase catalytic
APZ19_14305	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
APZ19_14315	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
APZ19_14320	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
APZ19_14325	ENOG4107SC1	transglycosylase
APZ19_14330	ENOG4105C5H	ABC transporter
APZ19_14340	ENOG4105DR5	peptidase
APZ19_14345	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
APZ19_14350	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
APZ19_14355	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
APZ19_14360	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
APZ19_14365	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APZ19_14385	ENOG4108HRK	Histidine kinase
APZ19_14390	ENOG4108NEV	two component transcriptional regulator, LytTR family
APZ19_14395	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
APZ19_14400	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
APZ19_14405	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
APZ19_14410	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
APZ19_14415	ENOG4105DTN	riboflavin biosynthesis protein ribF
APZ19_14420	ENOG4105CJR	Integral membrane protein (MviN
APZ19_14425	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
APZ19_14430	ENOG41080HT	Transcriptional regulator, arsr family
APZ19_14435	ENOG41063Z6	transcriptional regulator, lysR family
APZ19_14445	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
APZ19_14450	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
APZ19_14455	ENOG4105HF0	Membrane
APZ19_14460	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
APZ19_14465	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
APZ19_14470	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
APZ19_14480	ENOG4105CPC	Aldo Keto reductase
APZ19_14490	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_14495	ENOG4105CRK	lysyL-tRNA synthetase
APZ19_14505	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
APZ19_14510	ENOG4105T95	Thiol disulfide interChange protein
APZ19_14515	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
APZ19_14520	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
APZ19_14525	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
APZ19_14530	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
APZ19_14535	ENOG4105C1J	atp-dependent rna helicase
APZ19_14545	ENOG4105D1Q	UPF0246 protein
APZ19_14550	ENOG4105BZG	amino acid carrier protein
APZ19_14565	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
APZ19_14575	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
APZ19_14580	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
APZ19_14590	ENOG4105D98	threonine synthase
APZ19_14595	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
APZ19_14610	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
APZ19_14625	ENOG41065U4	response regulator
APZ19_14635	ENOG4105BZU	Histidine kinase
APZ19_14645	ENOG4105N5T	Radical SAM Protein
APZ19_14660	ENOG4105CBC	glutamate synthase
APZ19_14665	ENOG4105BZ8	glutamate synthase
APZ19_14675	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
APZ19_14685	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
APZ19_14690	ENOG4105EN6	Membrane
APZ19_14695	ENOG4105VP0	transcriptional regulator, lysR family
APZ19_14700	ENOG4105EJ9	Membrane
APZ19_14715	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
APZ19_14720	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
APZ19_14725	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
APZ19_14730	ENOG4105M6F	mutator MutT protein
APZ19_14735	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
APZ19_14745	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
APZ19_14750	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
APZ19_14755	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
APZ19_14760	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
APZ19_14765	ENOG4105DFU	Cell wall formation (By similarity)
APZ19_14770	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
APZ19_14780	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
APZ19_14785	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
APZ19_14790	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
APZ19_14795	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
APZ19_14800	ENOG4105CJN	penicillin-binding protein
APZ19_14805	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
APZ19_14810	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
APZ19_14825	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
APZ19_14835	ENOG41082RQ	UPF0102 protein
APZ19_14840	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
APZ19_14845	ENOG4105W4M	Transport-associated protein
APZ19_14850	ENOG4105KB2	stringent starvation protein b
APZ19_14855	ENOG4107MKT	Stringent starvation protein a
APZ19_14860	ENOG4105EIX	cytochrome c1
APZ19_14865	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
APZ19_14870	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
APZ19_14875	ENOG4108UJD	30S ribosomal protein S9
APZ19_14880	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
APZ19_14890	ENOG4105D6Z	AFG1 family ATPase
APZ19_14900	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
APZ19_14905	ENOG4105C0H	protease
APZ19_14910	ENOG4105C0H	protease
APZ19_14915	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APZ19_14920	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
APZ19_14925	ENOG4105IPS	esterase
APZ19_14930	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
APZ19_14935	ENOG4108SX3	cytoplasmic protein
APZ19_14940	ENOG41087AY	ADP-Ribose pyrophosphatase
APZ19_14945	ENOG4105DFG	type I secretion outer membrane protein
APZ19_14950	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
APZ19_14955	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
APZ19_14960	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_14970	ENOG4105I7R	Adenylate cyclase
APZ19_14975	ENOG4107IX6	phosphate transport regulator
APZ19_14980	ENOG4105CJ3	phosphate transporter
APZ19_14985	ENOG4106MWK	domain protein
APZ19_14990	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
APZ19_15005	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
APZ19_15010	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
APZ19_15015	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APZ19_15020	ENOG4107ZVW	dihydroneopterin aldolase
APZ19_15025	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
APZ19_15030	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
APZ19_15035	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
APZ19_15040	ENOG4105VCC	30S ribosomal protein S21
APZ19_15045	ENOG4105KTH	gatB Yqey
APZ19_15050	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
APZ19_15055	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APZ19_15085	ENOG4105CTS	PTS system mannitol-specific
APZ19_15090	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
APZ19_15095	ENOG4105E61	Mannitol repressor protein
APZ19_15100	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
APZ19_15105	ENOG4105GR3	Histidine kinase
APZ19_15125	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
APZ19_15130	ENOG410804X	Transcriptional regulator
APZ19_15140	ENOG4105CA9	Pyruvate kinase
APZ19_15150	ENOG4105BZU	Histidine kinase
APZ19_15155	ENOG4108ZP8	Acetolactate synthase small subunit
APZ19_15160	ENOG4105C7K	acetolactate synthase
APZ19_15165	ENOG4108IQE	Amp-dependent synthetase and ligase
APZ19_15170	ENOG41064T2	transcriptional regulator, lysR family
APZ19_15200	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
APZ19_15205	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
APZ19_15210	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APZ19_15215	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
APZ19_15225	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
APZ19_15230	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
APZ19_15235	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
APZ19_15240	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
APZ19_15245	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
APZ19_15250	ENOG4105NWN	ApaG protein
APZ19_15255	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
APZ19_15260	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
APZ19_15265	ENOG4107XM3	UPF0442 protein
APZ19_15270	ENOG4105DWK	Membrane
APZ19_15275	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
APZ19_15280	ENOG4105K46	50S ribosomal protein l27
APZ19_15285	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
APZ19_15290	ENOG4105EAH	synthase
APZ19_15300	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
APZ19_15305	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
APZ19_15330	ENOG4107T0D	ABC, transporter
APZ19_15335	ENOG4106SMU	thiamine transporter membrane protein
APZ19_15340	ENOG4105DP9	ABC transporter
APZ19_15345	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
APZ19_15350	ENOG4105DFU	Cell wall formation (By similarity)
APZ19_15355	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
APZ19_15360	ENOG4105F0N	pyrophosphate phospho-hydrolase
APZ19_15375	ENOG41066HZ	AIG2-like family
APZ19_15385	ENOG4105CFU	surface antigen
APZ19_15390	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
APZ19_15425	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
APZ19_15465	ENOG4105C7H	Helicase, RecD TraA family
APZ19_15495	ENOG4108UUE	Transcriptional regulator
APZ19_15510	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APZ19_15530	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
APZ19_15540	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
APZ19_15545	ENOG4105C11	sulfate adenylyltransferase), subunit 2
APZ19_15550	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APZ19_15555	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
APZ19_15570	ENOG4105C1J	atp-dependent rna helicase
APZ19_15575	ENOG4107YB6	acetyltransferase, (GNAT) family
APZ19_15590	ENOG4108V1T	peptidylprolyl cis-trans isomerase
APZ19_15600	ENOG4108ZT0	50S ribosomal protein l17
APZ19_15605	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
APZ19_15610	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
APZ19_15615	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
APZ19_15620	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APZ19_15630	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
APZ19_15635	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
APZ19_15640	ENOG4105VPB	50S ribosomal protein L30
APZ19_15645	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
APZ19_15655	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
APZ19_15660	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
APZ19_15665	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
APZ19_15670	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APZ19_15675	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
APZ19_15680	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
APZ19_15685	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
APZ19_15690	ENOG41083MP	50s ribosomal protein l29
APZ19_15695	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
APZ19_15700	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
APZ19_15705	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
APZ19_15710	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
APZ19_15715	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
APZ19_15720	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
APZ19_15725	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
APZ19_15730	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
APZ19_15735	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
APZ19_15740	ENOG4105VFB	Binds the 23S rRNA (By similarity)
APZ19_15750	ENOG4105C25	Primosomal protein n'
APZ19_15755	ENOG4105ETE	Transcriptional regulator (LacI family
APZ19_15765	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
APZ19_15770	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
APZ19_15775	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
APZ19_15780	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
APZ19_15785	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
APZ19_15790	ENOG4105CBT	Fructose-1,6-bisphosphatase
APZ19_15820	ENOG4105CP7	Triose-phosphate isomerase
APZ19_15835	ENOG4105ESV	Glycosyl transferase, family 4
APZ19_15840	ENOG4105C2X	Arabinose 5-phosphate isomerase
APZ19_15845	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
APZ19_15850	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
APZ19_15885	ENOG4108UT6	Transferase hexapeptide repeat containing protein
APZ19_15890	ENOG4105CHR	reductase
APZ19_15915	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
APZ19_15925	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
APZ19_15930	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
APZ19_15940	ENOG4105DAY	polysaccharide export protein
APZ19_15965	ENOG4105E3R	(LipO)protein
APZ19_15970	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
APZ19_15975	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
APZ19_15985	ENOG4105XA0	heptosyltransferase ii
APZ19_15990	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
APZ19_16005	ENOG4105CAQ	asparagine synthetase
APZ19_16010	ENOG4105D3Q	Sugar transferase
APZ19_16030	ENOG4105F0R	Cytidylyltransferase
APZ19_16035	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
APZ19_16040	ENOG41080IJ	Diacylglycerol kinase
APZ19_16045	ENOG4105DKP	glycosyl transferase, family 9
APZ19_16050	ENOG4106WTF	Glycosyl transferase, family 2
APZ19_16060	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
APZ19_16065	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
APZ19_16070	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
APZ19_16085	ENOG4105KDC	50s ribosomal protein l28
APZ19_16090	ENOG4105W5Q	DNA repair protein (RadC
APZ19_16095	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_16100	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
APZ19_16105	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
APZ19_16110	ENOG4105D1S	lipid A biosynthesis
APZ19_16115	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
APZ19_16120	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
APZ19_16125	ENOG4105DSJ	YicC domain protein
APZ19_16175	ENOG4105F5P	DNA-damage-inducible protein d
APZ19_16180	ENOG4105F5P	DNA-damage-inducible protein d
APZ19_16190	ENOG4105DZR	Type I site-specific deoxyribonuclease
APZ19_16215	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
APZ19_16225	ENOG4105DWP	Membrane
APZ19_16240	ENOG4108JQ7	(ABC) transporter
APZ19_16250	ENOG4107QRA	Extracellular solute-binding protein, family 5
APZ19_16255	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
APZ19_16260	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
APZ19_16290	ENOG4109015	Biopolymer transport protein exbD tolR
APZ19_16305	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
APZ19_16310	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
APZ19_16315	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
APZ19_16320	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
APZ19_16325	ENOG4105CB5	ATP-dependent DNA helicase recG
APZ19_16335	ENOG4105C2W	permease
APZ19_16340	ENOG4105E0F	Histidine kinase
APZ19_16345	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
APZ19_16350	ENOG4108RRZ	Transcription elongation factor GreB
APZ19_16360	ENOG4105BZM	domain protein
APZ19_16370	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
APZ19_16375	ENOG4105MJ2	Competence protein
APZ19_16380	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
APZ19_16385	ENOG4107RK2	ADP-ribose diphosphatase NudE
APZ19_16390	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
APZ19_16395	ENOG4105PIC	general secretion pathway protein N
APZ19_16400	ENOG4105U1E	general secretion pathway protein M
APZ19_16405	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
APZ19_16410	ENOG4108RTD	type II secretion system protein K
APZ19_16415	ENOG4108WWZ	General secretion pathway protein J
APZ19_16420	ENOG4105X5Z	General secretion pathway protein I
APZ19_16425	ENOG4105VWV	general secretion pathway protein h
APZ19_16430	ENOG4108VAU	general secretion pathway protein G
APZ19_16435	ENOG4105D7Q	type ii secretion system
APZ19_16440	ENOG4107QHF	type ii secretion system protein e
APZ19_16450	ENOG4108XKW	General secretion pathway protein C
APZ19_16455	ENOG4105VEJ	Heat shock protein
APZ19_16460	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
APZ19_16465	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
APZ19_16475	ENOG4105SUU	thioesterase domain
APZ19_16480	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
APZ19_16485	ENOG4107S2Z	UPF0761 membrane protein
APZ19_16505	ENOG4105C5F	glutamine synthetase
APZ19_16515	ENOG4105CUX	Signal transduction histidine kinase
APZ19_16520	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_16525	ENOG4105BZU	Histidine kinase
APZ19_16530	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
APZ19_16535	ENOG4105D4P	Coproporphyrinogen iii oxidase
APZ19_16540	ENOG4105XCT	Protein of unknown function (DUF2489)
APZ19_16545	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
APZ19_16560	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
APZ19_16570	ENOG4105C2M	dna polymerase I
APZ19_16585	ENOG4105D52	delta-aminolevulinic acid dehydratase
APZ19_16590	ENOG4105F8V	Hydrolase, tatD family
APZ19_16595	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
APZ19_16600	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
APZ19_16605	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
APZ19_16610	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
APZ19_16615	ENOG4105JC1	sterol-binding domain protein
APZ19_16625	ENOG4105CGY	Dna recombination protein
APZ19_16635	ENOG4105BZU	Histidine kinase
APZ19_16660	ENOG4105CVR	type I restriction-modification system
APZ19_16705	ENOG4105BZU	Histidine kinase
APZ19_16730	ENOG4105CBX	hi0933 family
APZ19_16760	ENOG4108V6B	universal stress protein B
APZ19_16765	ENOG41090A1	ferritin
APZ19_16770	ENOG4108M6U	Universal stress protein A
APZ19_16775	ENOG4105EMK	carboxylate amino acid amine transporter
APZ19_16785	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
APZ19_16790	ENOG4105BZU	Histidine kinase
APZ19_16795	ENOG4108VVK	transcriptional Regulator, AsnC
APZ19_16800	ENOG4105DGW	oligopeptidase A
APZ19_16805	ENOG4105D6S	protein involved in catabolism of external DNA
APZ19_16815	ENOG4105DC8	reductase
APZ19_16820	ENOG4108UHU	Aldolase
APZ19_16825	ENOG4105C6Z	Gluconate
APZ19_16830	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
APZ19_16835	ENOG4105C01	Dihydroxy-acid dehydratase
APZ19_16845	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
APZ19_16850	ENOG41064T2	transcriptional regulator, lysR family
APZ19_16855	ENOG4105DIQ	Transcriptional regulator
APZ19_16890	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
APZ19_16895	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
APZ19_16905	ENOG4108JQ6	ABC transporter
APZ19_16910	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APZ19_16940	ENOG4105MPD	Cytochrome
APZ19_16945	ENOG4105C4R	Atp-dependent dna helicase
APZ19_16950	ENOG4107Z3H	Transcriptional regulator, TetR family
APZ19_16955	ENOG410624X	efflux transporter, rnd family, mfp subunit
APZ19_16960	ENOG4105BZS	acriflavin resistance protein
APZ19_16970	ENOG4105W0Z	cytoplasmic protein
APZ19_16975	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
APZ19_16980	ENOG4105EMY	transcriptional regulator
APZ19_17025	ENOG4108Z0R	Transferase
APZ19_17030	ENOG4105SG3	Protein of unknown function (DUF1488)
APZ19_17035	ENOG4105E2X	shikimate dehydrogenase
APZ19_17040	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
APZ19_17045	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
APZ19_17050	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
APZ19_17055	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
APZ19_17060	ENOG4108WI1	Dna topoisomerase
APZ19_17065	ENOG4108RPN	Protein smg homolog
APZ19_17070	ENOG4105C79	DNA protecting protein DprA
APZ19_17085	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
APZ19_17090	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
APZ19_17095	ENOG4105C1A	potassium transporter peripheral membrane
APZ19_17100	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
APZ19_17110	ENOG4108UT2	hemolysin iii
APZ19_17115	ENOG4108N23	SpoOM-related protein
APZ19_17125	ENOG4105PC1	Conserved Protein
APZ19_17135	ENOG4105E27	serine threonine protein kinase
APZ19_17140	ENOG4108Z33	Thiol disulfide Interchange Protein
APZ19_17145	ENOG4106HNH	Acyl-transferase
APZ19_17155	ENOG4105C0P	Mg chelatase subunit ChlI
APZ19_17165	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
APZ19_17170	ENOG4105CM2	brancheD-chain amino acid aminotransferase
APZ19_17175	ENOG4105C01	Dihydroxy-acid dehydratase
APZ19_17180	ENOG4105C7B	Threonine dehydratase
APZ19_17185	ENOG4106TD9	Diguanylate cyclase
APZ19_17190	ENOG4105F52	Transcriptional regulator
APZ19_17195	ENOG4105CZQ	inner membrane transport protein YdhC
APZ19_17205	ENOG4105EAD	ABC transporter
APZ19_17210	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
APZ19_17215	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
APZ19_17220	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
APZ19_17225	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
APZ19_17230	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
APZ19_17235	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APZ19_17240	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APZ19_17245	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APZ19_17250	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
APZ19_17255	ENOG410684E	atp synthase
APZ19_17260	ENOG4105FA0	parb-like partition protein
APZ19_17265	ENOG4107QJE	Chromosome Partitioning Protein
APZ19_17270	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
APZ19_17275	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
APZ19_17280	ENOG4105QTB	Flavodoxin
APZ19_17285	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
APZ19_17290	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
APZ19_17295	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
APZ19_17300	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
APZ19_17310	ENOG4105CDA	abc transporter atp-binding protein
APZ19_17315	ENOG4105E5Q	amino acid AbC transporter
APZ19_17320	ENOG4105EAB	amino acid AbC transporter
APZ19_17325	ENOG41090HJ	UPF0265 protein
APZ19_17335	ENOG4108YXG	UPF0502 protein
APZ19_17340	ENOG41082IR	Excinuclease ABC C subunit domain protein
APZ19_17345	ENOG4108QGH	periplasmic
APZ19_17350	ENOG4105BZU	Histidine kinase
APZ19_17365	ENOG4105EW9	transcriptional regulator AsnC family
APZ19_17390	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APZ19_17395	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
APZ19_17415	ENOG4105CHU	acetyl-coa acetyltransferase
APZ19_17425	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
APZ19_17445	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
APZ19_17460	ENOG4105BZU	Histidine kinase
APZ19_17465	ENOG4105WH1	Two component transcriptional regulator luxr family
APZ19_17480	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
APZ19_17485	ENOG4107YWA	deoxycytidylate deaminase
APZ19_17500	ENOG4108N3W	hemolysin secretion protein
APZ19_17505	ENOG4108YZN	class I peptide chain release factor
APZ19_17510	ENOG4107VXZ	Hydrolase
APZ19_17540	ENOG4108V1T	peptidylprolyl cis-trans isomerase
APZ19_17550	ENOG4105CDV	Ompa motb domain protein
APZ19_17570	ENOG4105VEQ	Cold shock protein
APZ19_17585	ENOG4105BZU	Histidine kinase
APZ19_17605	ENOG4107R39	(ABC) transporter
APZ19_17615	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
APZ19_17635	ENOG4105DFG	type I secretion outer membrane protein
APZ19_17640	ENOG4108MGY	Histidine kinase
APZ19_17665	ENOG4108NVR	Methyl-accepting chemotaxis
APZ19_17670	ENOG4108RMU	ferritin dps family protein
APZ19_17680	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
APZ19_17690	ENOG4105C0A	alcohol dehydrogenase
APZ19_17695	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
APZ19_17715	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
APZ19_17720	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
APZ19_17725	ENOG4105MIR	Phenylalanine 4-monooxygenase
APZ19_17730	ENOG41090A4	Pterin carbinolamine dehydratase
APZ19_17760	ENOG4105VRT	cytoplasmic protein
APZ19_17780	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
APZ19_17790	ENOG4105CKI	cobalamin synthesis protein
APZ19_17795	ENOG4105BZU	Histidine kinase
APZ19_17800	ENOG4105C1J	atp-dependent rna helicase
APZ19_17820	ENOG4107XTP	(EAL) domain protein
APZ19_17825	ENOG4105DKW	ABC transporter
APZ19_17880	ENOG4107S17	Phosphate-binding protein
APZ19_17895	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
APZ19_17900	ENOG4105C1J	atp-dependent rna helicase
APZ19_17910	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
APZ19_17925	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
APZ19_17945	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
APZ19_17950	ENOG41060WC	Enoyl-CoA hydratase
APZ19_17955	ENOG4107QX3	carboxylase
APZ19_17960	ENOG4105C1G	acyl-Coa dehydrogenase
APZ19_17970	ENOG4105CHU	acetyl-coa acetyltransferase
APZ19_17975	ENOG4105C26	Dehydrogenase
APZ19_17985	ENOG4105E39	Enoyl-CoA hydratase
APZ19_17990	ENOG4105E39	Enoyl-CoA hydratase
APZ19_17995	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
APZ19_18000	ENOG4105CHR	reductase
APZ19_18005	ENOG4105E2S	oxidase) subunit II
APZ19_18010	ENOG4105BZ9	Cytochrome C oxidase, subunit I
APZ19_18015	ENOG4105CCU	oxidase (Subunit III)
APZ19_18020	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
APZ19_18025	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
APZ19_18030	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APZ19_18045	ENOG4105C26	Dehydrogenase
APZ19_18120	ENOG4105E5Z	arginine transporter ATP-binding subunit
APZ19_18125	ENOG4106PMH	Extracellular solute-binding protein family 3
APZ19_18130	ENOG4105GBT	ABC transporter
APZ19_18135	ENOG4105DMR	ABC, transporter
APZ19_18140	ENOG4107RK6	Methyl-accepting chemotaxis
APZ19_18150	ENOG4105DUM	transcriptional regulator, lysR family
APZ19_18160	ENOG4105ENH	Sulfatase
APZ19_18165	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
APZ19_18190	ENOG4105EXG	Transcriptional regulator
APZ19_18195	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
APZ19_18200	ENOG4105BZJ	Electron transfer flavoprotein
APZ19_18205	ENOG4105C10	Electron transfer flavoprotein
APZ19_18210	ENOG4107QSN	dihydrolipoamide acetyltransferase
APZ19_18215	ENOG4105CPP	Dehydrogenase, E1 component
APZ19_18220	ENOG4107RUY	(E1 component), alpha subunit
APZ19_18235	ENOG4105R8A	Heat shock protein
APZ19_18240	ENOG4106E5D	Protein of unknown function (DUF461)
APZ19_18270	ENOG4105ETX	regulatoR
APZ19_18285	ENOG4105G6Z	alkaline phosphatase
APZ19_18310	ENOG4105BZU	Histidine kinase
APZ19_18320	ENOG4105C44	Serine transporter
APZ19_18325	ENOG4105BZU	Histidine kinase
APZ19_18370	ENOG4105DG7	nitrate ABC transporter
APZ19_18375	ENOG4105D7T	ABC transporter
APZ19_18380	ENOG4107QZF	nitrite reductase NADPH large subunit
APZ19_18410	ENOG4105F8J	Adenylate Guanylate cyclase
APZ19_18420	ENOG4105BZU	Histidine kinase
APZ19_18430	ENOG4105ETX	regulatoR
APZ19_18435	ENOG4105F3H	Histidine kinase
APZ19_18440	ENOG4106855	Competence protein
APZ19_18445	ENOG4105ETX	regulatoR
APZ19_18460	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APZ19_18470	ENOG4105GTN	ParB Domain Protein Nuclease
APZ19_18525	ENOG41080TA	Multiple resistance and ph regulation protein f
APZ19_18530	ENOG4105KJM	monovalent cation h antiporter subunit g
APZ19_18535	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APZ19_18550	ENOG4105G2Y	Transcriptional regulator
APZ19_18560	ENOG4105DR5	peptidase
APZ19_18595	ENOG4105IPI	Membrane
APZ19_18615	ENOG4108V0E	nucleoside 2-deoxyribosyltransferase YtoQ
APZ19_18650	ENOG4105FTV	AraC Family Transcriptional Regulator
APZ19_18665	ENOG4105SBG	acid phosphatase
APZ19_18720	ENOG4105BZ1	(ABC) transporter
APZ19_18745	ENOG4105CR8	Transcriptional regulator
APZ19_18765	ENOG4105CNH	Multidrug resistance protein MdtL
APZ19_18790	ENOG4105ESI	atpase involved in dna repair
APZ19_18800	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
APZ19_18805	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
APZ19_18810	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
APZ19_18820	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
APZ19_18830	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
APZ19_18865	ENOG4105DM4	PTS System
APZ19_18870	ENOG4105DE4	1-phosphofructokinase
APZ19_18875	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
APZ19_18880	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
APZ19_18895	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
APZ19_18900	ENOG4105DRP	amino acid AbC transporter
APZ19_18905	ENOG4106TNF	Periplasmic binding protein
APZ19_18965	ENOG4108HJ1	Uncharacterized conserved protein (DUF2303)
APZ19_18990	ENOG4106CVF	DNA replication protein
APZ19_19250	ENOG4105EAD	ABC transporter
APZ19_19255	ENOG4105CDA	abc transporter atp-binding protein
APZ19_19265	ENOG4108I6A	alcohol dehydrogenase
APZ19_19270	ENOG4105CF7	AraC family transcriptional regulator
APZ19_19280	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
APZ19_19285	ENOG4105CKU	formyltetrahydrofolate synthetase
APZ19_19290	ENOG4107RE1	Inosine-guanosine kinase
APZ19_19305	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
APZ19_19310	ENOG4107YBY	Hydrolase
APZ19_19315	ENOG4108N3W	hemolysin secretion protein
APZ19_19325	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
APZ19_19330	ENOG4105C1J	atp-dependent rna helicase
APZ19_19335	ENOG4108M8H	domain protein
APZ19_19350	ENOG4105DS1	cytochrome b561
APZ19_19355	ENOG4108YYC	ycei family
APZ19_19360	ENOG4105TMB	Formate nitrite transporter
APZ19_19365	ENOG4105DUM	transcriptional regulator, lysR family
APZ19_19370	ENOG4108UQ5	membrane protein YcdZ
APZ19_19375	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
APZ19_19380	ENOG4105CGH	5'-nucleotidase
APZ19_19385	ENOG4105DU1	integral membrane protein, terc
APZ19_19400	ENOG4105C3R	Methionine synthase
APZ19_19415	ENOG4108M0H	Extracellular lipase
APZ19_19420	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
APZ19_19435	ENOG4105KA0	thioesterase Superfamily protein
APZ19_19470	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
APZ19_19480	ENOG4105BZU	Histidine kinase
APZ19_19485	ENOG4105RKW	reductase (By
APZ19_19495	ENOG4108I0Y	(ABC) transporter
APZ19_19500	ENOG4105CV6	ABC transporter, permease
APZ19_19515	ENOG4105P4J	Allophanate hydrolase, subunit 1
APZ19_19520	ENOG4105E7W	lamb ycsf family protein
APZ19_19525	ENOG4105BZU	Histidine kinase
APZ19_19530	ENOG4105CMR	udp-glucose 4-epimerase
APZ19_19545	ENOG4105CWB	LysR family transcriptional Regulator
APZ19_19550	ENOG4105CD5	CoA-binding domain protein
APZ19_19560	ENOG4105CPF	Cell wall formation (By similarity)
APZ19_19570	ENOG4108ZJT	translation initiation factor, Sui1
APZ19_19615	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APZ19_19620	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
APZ19_19645	ENOG4105BZU	Histidine kinase
APZ19_19670	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
APZ19_19675	ENOG4105E0C	molybdate abc transporter
APZ19_19680	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
APZ19_19685	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
APZ19_19690	ENOG4105WXI	Bacterial OB fold (BOF) protein
APZ19_19705	ENOG4105CGF	Aromatic amino acid aminotransferase
APZ19_19710	ENOG4105ECQ	AraC Family Transcriptional Regulator
APZ19_19715	ENOG4107QI1	Mate efflux family protein
APZ19_19720	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
APZ19_19725	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
APZ19_19795	ENOG4105CXY	transporter
APZ19_19800	ENOG4108KX4	response regulator
APZ19_19805	ENOG4105BZU	Histidine kinase
APZ19_19810	ENOG4105CXY	transporter
APZ19_19815	ENOG4105EIP	mannose-6-phosphate isomerase
APZ19_19825	ENOG4105IPI	Membrane
APZ19_19835	ENOG4105EFX	secretion protein, HlyD family
APZ19_19865	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
APZ19_19870	ENOG4105K63	Thioredoxin
APZ19_19875	ENOG4108ISG	Major Facilitator
APZ19_19885	ENOG4107QI1	Mate efflux family protein
APZ19_19890	ENOG4105VXR	cytoplasmic protein
APZ19_19905	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
APZ19_19920	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
APZ19_19925	ENOG4105TMB	Formate nitrite transporter
APZ19_19930	ENOG4105WZK	nitrite reductase NADPH small subunit
APZ19_19935	ENOG4107QZF	nitrite reductase NADPH large subunit
APZ19_19945	ENOG4108KHX	Diguanylate cyclase
APZ19_20020	ENOG4105CXG	d-lactate dehydrogenase
APZ19_20025	ENOG4105CBN	LysR family transcriptional regulator
APZ19_20030	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
APZ19_20040	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
APZ19_20045	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
APZ19_20055	ENOG4105C5W	Aldolase
APZ19_20065	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
APZ19_20075	ENOG4105C2C	drug resistance transporter, Bcr CflA
APZ19_20085	ENOG4105QNF	Outer membrane lipoprotein
APZ19_20115	ENOG4105E03	chitinase
APZ19_20125	ENOG4105EYH	Exonuclease
APZ19_20130	ENOG4107RFY	SbcCD D subunit
APZ19_20155	ENOG4105CS6	Rhs element vgr protein
APZ19_20165	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APZ19_20210	ENOG4108ZF3	Phosphatase
APZ19_20225	ENOG4106VK6	Flagellar motor protein
APZ19_20245	ENOG4105D9P	serine threonine protein kinase
APZ19_20285	ENOG4108UYE	Lactoylglutathione lyase
APZ19_20290	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APZ19_20300	ENOG4105EXC	Acyl-transferase
APZ19_20315	ENOG4105CBC	glutamate synthase
APZ19_20325	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
APZ19_20330	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
APZ19_20340	ENOG4107RGH	Aldehyde dehydrogenase
APZ19_20360	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
APZ19_20365	ENOG4105KPY	Small multidrug resistance protein
APZ19_20375	ENOG4106CKV	Pap2 superfamily protein
APZ19_20390	ENOG4105FR1	rard protein
APZ19_20400	ENOG4108VAU	general secretion pathway protein G
APZ19_20405	ENOG4107R88	Chemotaxis protein (CheV)
APZ19_20410	ENOG4108TVJ	Nitroreductase
APZ19_20420	ENOG4108WQH	regulatoR
APZ19_20430	ENOG4105BZU	Histidine kinase
APZ19_20435	ENOG4108WQH	regulatoR
APZ19_20440	ENOG4105BZU	Histidine kinase
APZ19_20445	ENOG4105BZU	Histidine kinase
APZ19_20450	ENOG4105BZU	Histidine kinase
APZ19_20460	ENOG4105D05	Receptor
APZ19_20515	ENOG4105EW9	transcriptional regulator AsnC family
APZ19_20550	ENOG4105D9P	serine threonine protein kinase
APZ19_20575	ENOG4105CS6	Rhs element vgr protein
APZ19_20580	ENOG4108WC9	type VI secretion system effector, hcp1 family
APZ19_20585	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
APZ19_20590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_20595	ENOG4105KCK	Peptidoglycan-associated lipoprotein
APZ19_20630	ENOG4105DR5	peptidase
APZ19_20635	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
APZ19_20640	ENOG4107KBT	8-Amino-7-oxononanoate synthase
APZ19_20645	ENOG4108MGY	Histidine kinase
APZ19_20665	ENOG4105CEE	C4-dicarboxylate transporter
APZ19_20670	ENOG4108V0P	LemA family
APZ19_20675	ENOG4105D0M	Protease HtpX homolog
APZ19_20695	ENOG4105F2V	VRR-NUC domain-containing protein
APZ19_20705	ENOG4105C4X	radical SAM domain protein
APZ19_20725	ENOG4108YDI	single-species biofilm formation on inanimate substrate
APZ19_20730	ENOG4107TE5	Lipid kinase
APZ19_20735	ENOG41064T2	transcriptional regulator, lysR family
APZ19_20740	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
APZ19_20745	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
APZ19_20750	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
APZ19_20755	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
APZ19_20760	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
APZ19_20765	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APZ19_20770	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
APZ19_20775	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
APZ19_20780	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
APZ19_20815	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APZ19_20820	ENOG4105C4X	radical SAM domain protein
APZ19_20825	ENOG4105ENH	Sulfatase
APZ19_20830	ENOG4105DQS	Transcriptional regulator
APZ19_20840	ENOG4105ENH	Sulfatase
APZ19_20845	ENOG4105ENH	Sulfatase
APZ19_20850	ENOG4105ENH	Sulfatase
APZ19_20860	ENOG410804D	Sensor Signal Transduction Histidine Kinase
APZ19_20880	ENOG4105BZU	Histidine kinase
APZ19_20885	ENOG4108SV3	Tmao reductase system periplasmic protein tort
APZ19_20890	ENOG4108Z5K	methylglyoxal synthase
APZ19_20895	ENOG41088T4	Helicase IV
APZ19_20900	ENOG4105EM2	membrane
APZ19_20930	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
APZ19_20940	ENOG4108Z6Z	Transcriptional regulator
APZ19_20945	ENOG4108IPW	abc transporter atp-binding protein
APZ19_20950	ENOG4105CM4	permease protein
APZ19_20955	ENOG4105DHS	permease protein
APZ19_20975	ENOG4108I5U	Uridine phosphorylase
APZ19_20980	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
APZ19_20990	ENOG4105ETE	Transcriptional regulator (LacI family
APZ19_20995	ENOG4108RVA	ribokinase
APZ19_21000	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
APZ19_21005	ENOG4105CNN	ABC, transporter
APZ19_21010	ENOG4105C2J	ABC transporter
APZ19_21015	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
APZ19_21020	ENOG4108K0B	C-di-gmp phosphodiesterase
APZ19_21025	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
APZ19_21060	ENOG4106W5V	Membrane
APZ19_21090	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
APZ19_21095	ENOG4105BZU	Histidine kinase
APZ19_21125	ENOG4105HEI	LysR family (Transcriptional regulator
APZ19_21135	ENOG4105BZU	Histidine kinase
APZ19_21140	ENOG4105CA0	peroxidase
APZ19_21145	ENOG4105BZU	Histidine kinase
APZ19_21150	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
APZ19_21180	ENOG4107QX8	SPFH domain, Band 7 family protein
APZ19_21190	ENOG4108RCM	Nitroreductase
APZ19_21235	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
APZ19_21245	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
APZ19_21260	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
APZ19_21275	ENOG4105E2K	Glycosyl transferase (Group 1
APZ19_21300	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
APZ19_21305	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
APZ19_21310	ENOG4105C11	sulfate adenylyltransferase), subunit 2
APZ19_21315	ENOG4105D75	Capsular exopolysaccharide family
APZ19_21320	ENOG4105DAY	polysaccharide export protein
APZ19_21325	ENOG4105D3Q	Sugar transferase
APZ19_21330	ENOG4108IJ7	Glycine betaine
APZ19_21335	ENOG4108HQS	Glycine betaine
APZ19_21345	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
APZ19_21350	ENOG4105C26	Dehydrogenase
APZ19_21355	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
APZ19_21360	ENOG4107RGH	Aldehyde dehydrogenase
APZ19_21370	ENOG4105BZU	Histidine kinase
APZ19_21380	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
APZ19_21410	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
APZ19_21415	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
APZ19_21425	ENOG4108UNF	response regulator
APZ19_21430	ENOG4107RGM	aldo keto reductase
APZ19_21455	ENOG4105C5A	transporter
APZ19_21460	ENOG4105EUJ	GTP cyclohydrolase i
APZ19_21465	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
APZ19_21470	ENOG4105D06	uba thif-type nad fad binding protein
APZ19_21490	ENOG4105KHC	sulfurtransferase
APZ19_21495	ENOG4105BZU	Histidine kinase
APZ19_21510	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
APZ19_21520	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
APZ19_21525	ENOG4105DXI	Major Facilitator superfamily
APZ19_21530	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
APZ19_21535	ENOG4105UYK	outer membrane protein a
APZ19_21540	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
APZ19_21545	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
APZ19_21570	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
APZ19_21615	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
APZ19_21630	ENOG4108SXK	Transporter Drug Metabolite Exporter family
APZ19_21650	ENOG4105E5M	Multidrug resistance protein D
APZ19_21655	ENOG4105CR8	Transcriptional regulator
APZ19_21660	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
APZ19_21670	ENOG4105E0K	tonB-dependent siderophore receptor
APZ19_21675	ENOG4105HFT	AraC family transcriptional regulator
APZ19_21685	ENOG4105E0A	ABC, transporter
APZ19_21695	ENOG4105DR5	peptidase
APZ19_21720	ENOG4105DWD	nucleoside recognition domain protein
APZ19_21725	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_21735	ENOG4105E0U	tyrosine-specific transport protein
APZ19_21755	ENOG4107Z1W	Fructose transport system kinase
APZ19_21765	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
APZ19_21770	ENOG4105CTS	PTS system mannitol-specific
APZ19_21775	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
APZ19_21780	ENOG4105FDP	GntR family transcriptional regulator
APZ19_21785	ENOG4105DM4	PTS System
APZ19_21790	ENOG4105C8I	hydrolase, family 38
APZ19_21795	ENOG4105EIP	mannose-6-phosphate isomerase
APZ19_21805	ENOG4107RGM	aldo keto reductase
APZ19_21810	ENOG4105JQN	Transcriptional regulator
APZ19_21825	ENOG4105KVH	Transcriptional regulator
APZ19_21840	ENOG4105D6J	arsenicaL-resistance protein
APZ19_21855	ENOG4108V1U	phospholipid-binding protein
APZ19_21860	ENOG4105JAB	phenazine biosynthesis protein, phzf family
APZ19_21865	ENOG4107YYT	May reduce aminoacrylate peracid to aminoacrylate. Required to remove a toxic intermediate produce by the pyrimidine nitrogen degradation (By similarity)
APZ19_21870	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
APZ19_21875	ENOG4105E2D	ec 3.2.1.52
APZ19_21880	ENOG4108UHU	Aldolase
APZ19_21885	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
APZ19_21890	ENOG4108IA2	Sodium pantothenate symporter
APZ19_21915	ENOG4108NVR	Methyl-accepting chemotaxis
APZ19_21925	ENOG4105CJ1	ABC, transporter
APZ19_21930	ENOG4107QWP	ABC-2 type transporter
APZ19_21945	ENOG4108IEG	Formate dehydrogenase Alpha subunit
APZ19_21965	ENOG4108IJF	Heavy metal efflux pump, CzcA
APZ19_22010	ENOG4105M6F	mutator MutT protein
APZ19_22025	ENOG4105CA0	peroxidase
APZ19_22035	ENOG4108HK0	-acetyltransferase
APZ19_22045	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
APZ19_22060	ENOG4105C5H	ABC transporter
APZ19_22085	ENOG4108M6U	Universal stress protein A
APZ19_22095	ENOG4105E98	transcriptional regulator DeoR family
APZ19_22110	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
APZ19_22115	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
APZ19_22120	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
APZ19_22140	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
APZ19_22160	ENOG4105CKI	cobalamin synthesis protein
APZ19_22170	ENOG4105CD3	dihydroorotase
APZ19_22180	ENOG4108NRW	Phospholipase, patatin family
APZ19_22185	ENOG4105EUB	pirin domain protein
APZ19_22190	ENOG4105VEQ	Cold shock protein
APZ19_22205	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
APZ19_22210	ENOG4105BZU	Histidine kinase
APZ19_22235	ENOG4105DMQ	Methyltransferase
APZ19_22245	ENOG4105BZU	Histidine kinase
APZ19_22250	ENOG4105DZ1	carboxypeptidase
APZ19_22255	ENOG4105C94	Transporter
APZ19_22260	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
APZ19_22265	ENOG4105JQN	Transcriptional regulator
APZ19_22270	ENOG4105CYM	Glutathione S-transferase
APZ19_22280	ENOG4105NAE	bifunctional deaminase-reductase domain protein
APZ19_22290	ENOG4105CHR	reductase
APZ19_22315	ENOG4108P3C	
APZ19_22330	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
APZ19_22340	ENOG4105EJC	lysr family transcriptional regulator
APZ19_22345	ENOG410874W	AraC family transcriptional regulator
APZ19_22350	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APZ19_22380	ENOG4105C1J	atp-dependent rna helicase
APZ19_22390	ENOG4105ETT	transcriptional Regulator, LysR family
APZ19_22410	ENOG4105CHR	reductase
APZ19_22415	ENOG4105F27	Major Facilitator
APZ19_22425	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
APZ19_22440	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
APZ19_22445	ENOG4105DDW	LysR family Transcriptional regulator
APZ19_22470	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
APZ19_22485	ENOG4105HDK	L-asparaginase
APZ19_22490	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
APZ19_22495	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
APZ19_22505	ENOG4108S01	response regulator
APZ19_22510	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
APZ19_22520	ENOG4105G2Y	Transcriptional regulator
APZ19_22560	ENOG4105HEI	LysR family (Transcriptional regulator
APZ19_22565	ENOG4107V40	secretion protein, HlyD family
APZ19_22575	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
APZ19_22580	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
APZ19_22585	ENOG4105D6U	Sodium Glutamate Symporter
APZ19_22595	ENOG4105BZU	Histidine kinase
APZ19_22605	ENOG41086KC	Transcriptional regulator
APZ19_22620	ENOG4105CEY	Amp-dependent synthetase and ligase
APZ19_22640	ENOG4105BZS	acriflavin resistance protein
APZ19_22650	ENOG4105BZS	acriflavin resistance protein
APZ19_22660	ENOG4107RZC	phospholipase d
APZ19_22690	ENOG4108Z4X	TRANSCRIPTIONal
APZ19_22705	ENOG4108HKT	sucrose-6-phosphate hydrolase
APZ19_22710	ENOG4105C5Y	PTS System
APZ19_22715	ENOG4105FDP	GntR family transcriptional regulator
APZ19_22730	ENOG4107S8C	mandelate racemase muconate lactonizing
APZ19_22735	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
APZ19_22745	ENOG4105BZU	Histidine kinase
APZ19_22770	ENOG4105VYW	UPF0251 protein
APZ19_22780	ENOG4108HQS	Glycine betaine
APZ19_22785	ENOG4108IJ7	Glycine betaine
APZ19_22800	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
APZ19_22805	ENOG4105ETT	transcriptional Regulator, LysR family
APZ19_22830	ENOG4105RA2	Membrane
APZ19_22845	ENOG4107RH7	Nicotinate phosphoribosyltransferase
APZ19_22855	ENOG4108RWI	nicotinamidase
APZ19_22860	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
APZ19_22870	ENOG4105CH6	catalase
APZ19_22890	ENOG4105EIP	mannose-6-phosphate isomerase
APZ19_22895	ENOG4105C87	Aminotransferase class I and II
APZ19_22900	ENOG4105CI1	PTS System
APZ19_22905	ENOG4107P2S	Transcriptional regulator
APZ19_22910	ENOG4105N2W	Transcriptional regulator
APZ19_22915	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
APZ19_22920	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
APZ19_22930	ENOG4105DM4	PTS System
APZ19_22935	ENOG4105CWX	Alpha-1,2-mannosidase
APZ19_22940	ENOG4105CWX	Alpha-1,2-mannosidase
APZ19_22950	ENOG4105CWX	Alpha-1,2-mannosidase
APZ19_22955	ENOG4105CWX	Alpha-1,2-mannosidase
APZ19_22960	ENOG4105CGH	5'-nucleotidase
APZ19_22990	ENOG4105N14	lysine exporter protein LysE YggA
APZ19_22995	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
APZ19_23010	ENOG4105W1N	transcriptional regulator
APZ19_23025	ENOG4105HEI	LysR family (Transcriptional regulator
APZ19_23055	ENOG4105Q8W	reductase
APZ19_23060	ENOG4105HEI	LysR family (Transcriptional regulator
APZ19_23065	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
APZ19_23070	ENOG4105C5H	ABC transporter
APZ19_23085	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
APZ19_23090	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
APZ19_23105	ENOG4105E18	UPF0276 protein
APZ19_23120	ENOG4105C4M	(Ubiquinol oxidase) subunit I
APZ19_23125	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
APZ19_23160	ENOG4107U2T	alpha beta
APZ19_23165	ENOG4105E7U	AraC family transcriptional regulator
APZ19_23170	ENOG41075H3	AraC family transcriptional regulator
APZ19_23180	ENOG4105C6N	Formate acetyltransferase
APZ19_23185	ENOG4105F1A	Pyruvate formate-lyase
APZ19_23190	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
APZ19_23205	ENOG4105EB3	Histidine kinase
APZ19_23210	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
APZ19_23220	ENOG4105I4A	GCN5-related N-acetyltransferase
APZ19_23225	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
APZ19_23235	ENOG4105CNH	Multidrug resistance protein MdtL
APZ19_23240	ENOG4105G2Y	Transcriptional regulator
APZ19_23250	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
APZ19_23290	ENOG4105IPI	Membrane
APZ19_23295	ENOG41068P6	UPF0319 protein
APZ19_23310	ENOG4105DP0	ferredoxin-NADP reductase
APZ19_23320	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
APZ19_23325	ENOG4105EJC	lysr family transcriptional regulator
APZ19_23335	ENOG4108RCM	Nitroreductase
APZ19_23350	ENOG4105DZ1	carboxypeptidase
APZ19_23370	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APZ19_23375	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
APZ19_23380	ENOG4105C72	UPF0176 protein
APZ19_23400	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
APZ19_23415	ENOG4108NRW	Phospholipase, patatin family
APZ19_23420	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
APZ19_23430	ENOG4105DAY	polysaccharide export protein
APZ19_23435	ENOG4107ZF2	Phosphatase
APZ19_23450	ENOG4105N0V	mono-oxygenase ydhR
APZ19_23455	ENOG4105C5Q	Transcriptional regulator
APZ19_23460	ENOG4105F27	Major Facilitator
APZ19_23490	ENOG4105CK2	sodium dicarboxylate symporter
APZ19_23500	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
APZ19_23505	ENOG4108P2H	Inner membrane protein YjiG
APZ19_23510	ENOG41074DU	domain protein
APZ19_23525	ENOG4107T9C	Alpha amylase catalytic region
APZ19_23535	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
APZ19_23540	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
APZ19_23545	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
APZ19_23550	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
APZ19_23555	ENOG41061ZR	Transcriptional regulator
APZ19_23580	ENOG4105CI1	PTS System
APZ19_23585	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
APZ19_23590	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
APZ19_23620	ENOG4105EDK	PfkB domain protein
APZ19_23625	ENOG4105CIB	oxidoreductase Domain protein
APZ19_23630	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
APZ19_23640	ENOG4107QNK	)-transporter
APZ19_23660	ENOG4105CHU	acetyl-coa acetyltransferase
APZ19_23665	ENOG4107QP7	CoA-transferase subunit A
APZ19_23680	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
APZ19_23690	ENOG4105D5Q	Arginine ornithine antiporter
APZ19_23695	ENOG4105CXN	decarboxylase
APZ19_23715	ENOG4108K8S	endonuclease I
APZ19_23735	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
APZ19_23745	ENOG4105BZU	Histidine kinase
APZ19_23755	ENOG4105D5B	Sulfite reductase, subunit A
APZ19_23760	ENOG4107SHJ	sulfite reductase subunit b
APZ19_23765	ENOG410810Y	Sulfite reductase
APZ19_23770	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
APZ19_23785	ENOG4105C5Y	PTS System
APZ19_23790	ENOG4105CHR	reductase
APZ19_23795	ENOG4105EJQ	L-serine dehydratase
APZ19_23805	ENOG4105D2S	major facilitator superfamily
APZ19_23820	ENOG4105ETE	Transcriptional regulator (LacI family
APZ19_23830	ENOG4105E5M	Multidrug resistance protein D
APZ19_23835	ENOG4105T0Z	Conserved Protein
APZ19_23845	ENOG4105D05	Receptor
APZ19_23860	ENOG4105DHS	permease protein
APZ19_23865	ENOG4105CM4	permease protein
APZ19_23870	ENOG4108IPW	abc transporter atp-binding protein
APZ19_23875	ENOG41062JF	Transcriptional regulator
APZ19_23895	ENOG4105DR5	peptidase
APZ19_23910	ENOG4108UHU	Aldolase
APZ19_23915	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
APZ19_23920	ENOG4105C5Y	PTS System
APZ19_23930	ENOG4105FDP	GntR family transcriptional regulator
APZ19_23935	ENOG4107QW3	Sucrose phosphorylase
APZ19_23940	ENOG4108HKT	sucrose-6-phosphate hydrolase
APZ19_23950	ENOG4108IJ9	(ABC) transporter
APZ19_23955	ENOG4107URF	beta-phospho-glucomutase
APZ19_23960	ENOG4105C71	hydrolase family 65, central catalytic
APZ19_23965	ENOG4105DRS	transport system, permease
APZ19_23970	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
APZ19_24000	ENOG4108FZ9	Chaperone
APZ19_24005	ENOG4106PG1	outer membrane usher protein
APZ19_24035	ENOG4107RAN	Peptidase, M16
APZ19_24040	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_24055	ENOG4105CFP	Peptidase U32
APZ19_24070	ENOG4105CPC	Aldo Keto reductase
APZ19_24080	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
APZ19_24090	ENOG410642W	LysR family Transcriptional regulator
APZ19_24100	ENOG4105C19	ABC transporter
APZ19_24150	ENOG4108ZHJ	Organic hydroperoxide resistance protein
APZ19_24155	ENOG4105K56	Transcriptional regulator
APZ19_24160	ENOG4105D3R	alkyl hydroperoxide reductase
APZ19_24165	ENOG4108JU3	Alkyl hydroperoxide reductase
APZ19_24185	ENOG4105FDP	GntR family transcriptional regulator
APZ19_24190	ENOG4105DJB	Major Facilitator Superfamily
APZ19_24195	ENOG4108TFM	Kinase, PfkB family
APZ19_24200	ENOG4108KD5	ADP-ribosylation crystallin J1
APZ19_24205	ENOG4105EAA	nucleoside
APZ19_24225	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
APZ19_24230	ENOG4108N3W	hemolysin secretion protein
APZ19_24240	ENOG4105F4I	Transcriptional regulator
APZ19_24250	ENOG4108XM1	transcriptional regulator AsnC family
APZ19_24265	ENOG4108RPX	mosc domain containing protein
APZ19_24270	ENOG41060NJ	transcriptional regulator
APZ19_24275	ENOG4105DFD	Na H antiporter
APZ19_24280	ENOG4105C87	Aminotransferase class I and II
APZ19_24285	ENOG4105C1J	atp-dependent rna helicase
APZ19_24300	ENOG4105EXG	Transcriptional regulator
APZ19_24305	ENOG410904A	RNA polymerase
APZ19_24315	ENOG4105C87	Aminotransferase class I and II
APZ19_24320	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
APZ19_24325	ENOG4105C6F	GntR Family Transcriptional Regulator
APZ19_24330	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
APZ19_24335	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
APZ19_24340	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
APZ19_24345	ENOG4105DEI	Mannitol dehydrogenase
APZ19_24355	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
APZ19_24360	ENOG4108UHU	Aldolase
APZ19_24365	ENOG4105P66	Membrane
APZ19_24370	ENOG4105EJ2	Transcriptional regulator
APZ19_24380	ENOG410839U	amino acid
APZ19_24410	ENOG4105BZ1	(ABC) transporter
APZ19_24420	ENOG4105EW9	transcriptional regulator AsnC family
APZ19_24435	ENOG4105CVJ	phosphoglycerate mutase
APZ19_24440	ENOG4105KNA	-acetyltransferase
APZ19_24460	ENOG4105CK7	Sodium proline symporter
APZ19_24470	ENOG4105C26	Dehydrogenase
APZ19_24485	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
APZ19_24490	ENOG4105CQZ	Histidine kinase
APZ19_24495	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_24500	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
APZ19_24515	ENOG4108JJA	ABC, transporter
APZ19_24530	ENOG4108J59	Extracellular solute-binding protein, family 5
APZ19_24540	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
APZ19_24545	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APZ19_24550	ENOG4105C5Y	PTS System
APZ19_24555	ENOG4105FCK	Membrane
APZ19_24565	ENOG4105EQ2	LysR family Transcriptional regulator
APZ19_24580	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
APZ19_24585	ENOG4106RMF	ParB family
APZ19_24605	ENOG4108JQ7	(ABC) transporter
APZ19_24630	ENOG4105BZU	Histidine kinase
APZ19_24640	ENOG4105CDY	transcriptional regulatory protein
APZ19_24645	ENOG4105CNI	cell division protein FtsW
APZ19_24655	ENOG4105Y49	secretion protein, HlyD family
APZ19_24660	ENOG4105CR8	Transcriptional regulator
APZ19_24670	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
APZ19_24690	ENOG4108HRK	Histidine kinase
APZ19_24695	ENOG4108VAC	response regulator
APZ19_24705	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
APZ19_24710	ENOG4105C8Q	Methyl-accepting chemotaxis
APZ19_24730	ENOG4105D6U	Sodium Glutamate Symporter
APZ19_24745	ENOG4105CZV	ABC transporter
APZ19_24750	ENOG4107U9B	transcriptional regulator
APZ19_24755	ENOG4105D6U	Sodium Glutamate Symporter
APZ19_24775	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
APZ19_24790	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
APZ19_24795	ENOG4108YZ9	Urea amidohydrolase subunit gamma
APZ19_24800	ENOG4105KI2	Urea amidohydrolase subunit beta
APZ19_24805	ENOG4105CQM	Urea amidohydrolase subunit alpha
APZ19_24810	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
APZ19_24815	ENOG4105IY8	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
APZ19_24820	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
APZ19_24830	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
APZ19_24835	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
APZ19_24845	ENOG4105EHG	Permease protein
APZ19_24855	ENOG4105KME	endoribonuclease L-psp
APZ19_24860	ENOG4105NXH	GreA GreB family elongation factor
APZ19_24905	ENOG4108K4B	hydrolase
APZ19_24915	ENOG41064BZ	L-xylulose 5-phosphate 3-epimerase
APZ19_24935	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
APZ19_24955	ENOG4105C2I	pirin domain protein
APZ19_24960	ENOG4108VGI	doxx family
APZ19_24970	ENOG4105D03	DNA-3-methyladenine glycosylase II
APZ19_24975	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
APZ19_24995	ENOG4105DN9	Na H antiporter
APZ19_25095	ENOG4105NBK	UPF0345 protein
APZ19_25105	ENOG4108K0B	C-di-gmp phosphodiesterase
APZ19_25110	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
APZ19_25115	ENOG41060NJ	transcriptional regulator
APZ19_25130	ENOG4105DRS	transport system, permease
APZ19_25140	ENOG4108IJ9	(ABC) transporter
APZ19_25145	ENOG4105ETE	Transcriptional regulator (LacI family
APZ19_25150	ENOG4105UQX	Mate efflux family protein
APZ19_25155	ENOG4105D3G	Pseudouridine synthase
APZ19_25170	ENOG4108HCJ	Hydrolase
APZ19_25180	ENOG4108KHX	Diguanylate cyclase
APZ19_25190	ENOG4105KAF	membrAne
APZ19_25210	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
APZ19_25225	ENOG4105CC0	LysR family Transcriptional regulator
APZ19_25235	ENOG4105EGI	Transcriptional regulator
APZ19_25240	ENOG4105Q26	Siderophore-interacting protein
APZ19_25255	ENOG4105EW9	transcriptional regulator AsnC family
APZ19_25260	ENOG4108M1A	Chitin-binding protein
APZ19_25270	ENOG410814C	multidrug resistance protein
APZ19_25285	ENOG4107W31	Pentapeptide repeat protein
APZ19_25290	ENOG4105EIF	outer membrane protein W
APZ19_25310	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
APZ19_25330	ENOG4107WCA	isomerase
APZ19_25345	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
APZ19_25385	ENOG4105G2Y	Transcriptional regulator
APZ19_25400	ENOG4105D9N	nucleoside
APZ19_25410	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
APZ19_25435	ENOG4105CI2	imidazolone-5-propionate hydrolase
APZ19_25445	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
APZ19_25450	ENOG4105BZW	Glycerate kinase
APZ19_25455	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
APZ19_25500	ENOG4108W0I	acetyltransferase
APZ19_25520	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
APZ19_25530	ENOG4105CUW	cytochrome C-TYPE protein
APZ19_25535	ENOG4107QY8	reductase
APZ19_25540	ENOG4105GR3	Histidine kinase
APZ19_25550	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
APZ19_25565	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
APZ19_25570	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
APZ19_25575	ENOG4105ETU	transcriptional activator (TenA
APZ19_25580	ENOG4107Z6I	Thiamine biosynthesis protein
APZ19_25585	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
APZ19_25590	ENOG4108YI8	ABC transporter
APZ19_25595	ENOG4105DWF	phosphomethylpyrimidine kinase
APZ19_25610	ENOG4108TEM	pseudouridine methyltransferase
APZ19_25665	ENOG4108YYI	Protein of unknown function (DUF2810)
APZ19_25670	ENOG4105C5I	Dehydrogenase
APZ19_25680	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
APZ19_25685	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
APZ19_25690	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
APZ19_25695	ENOG410804D	Sensor Signal Transduction Histidine Kinase
APZ19_25720	ENOG4109015	Biopolymer transport protein exbD tolR
APZ19_25765	ENOG4105DSE	periplasmic solute binding protein
APZ19_25770	ENOG4105DIK	(ABC) transporter
APZ19_25775	ENOG4105CC5	ABC transporter
APZ19_25790	ENOG4105CUG	Oligopeptidase b
APZ19_25795	ENOG4105E5M	Multidrug resistance protein D
APZ19_25800	ENOG4105CYW	agmatinase
APZ19_25805	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
APZ19_25815	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
APZ19_25820	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
APZ19_25840	ENOG4108WAV	Transcriptional regulator
APZ19_25870	ENOG4105CQZ	Histidine kinase
APZ19_25875	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_25880	ENOG4105BZU	Histidine kinase
APZ19_25885	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
APZ19_25905	ENOG4105D5U	fad dependent oxidoreductase
APZ19_25920	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
APZ19_25925	ENOG4105C0F	tryptophanase EC 4.1.99.1
APZ19_25940	ENOG4105D9N	nucleoside
APZ19_25945	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
APZ19_25965	ENOG4105BZU	Histidine kinase
APZ19_25980	ENOG4106TD9	Diguanylate cyclase
APZ19_25985	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
APZ19_25990	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
APZ19_26005	ENOG4105E0X	reductase
APZ19_26010	ENOG4108UKZ	OsmC family
APZ19_26015	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
APZ19_26045	ENOG4105JQN	Transcriptional regulator
APZ19_26050	ENOG4105PAD	Hydrolase
APZ19_26085	ENOG4105KUU	lipolytic protein G-D-S-L family
APZ19_26090	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
APZ19_26115	ENOG4105ETE	Transcriptional regulator (LacI family
APZ19_26120	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
APZ19_26125	ENOG4108JPW	Aminotransferase
APZ19_26130	ENOG4107STF	Involved in phosphonate degradation (By similarity)
APZ19_26145	ENOG4107RCV	ABC transporter, permease
APZ19_26165	ENOG4108MJ5	VirK protein
APZ19_26175	ENOG4105CJP	fad dependent oxidoreductase
APZ19_26190	ENOG4105ETT	transcriptional Regulator, LysR family
APZ19_26210	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
APZ19_26215	ENOG4105DUX	Transporter
APZ19_26220	ENOG4105EJQ	L-serine dehydratase
APZ19_26245	ENOG4105E9H	Lytic Murein transglycosylase
APZ19_26265	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
APZ19_26270	ENOG4108ZC9	flagellar basal-body rod protein flgc
APZ19_26275	ENOG4105W00	Flagellar hook capping protein
APZ19_26280	ENOG4105BZE	flagellar hook protein, FlgE
APZ19_26285	ENOG4108KPB	Flagellar basal-body rod protein FlgF
APZ19_26290	ENOG4105CGA	flagellar basal-body rod protein FlgG
APZ19_26295	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
APZ19_26300	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
APZ19_26305	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
APZ19_26310	ENOG4105E1Q	flagellar hook-associated protein
APZ19_26315	ENOG4105DTJ	flagellar hook-associated protein
APZ19_26335	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
APZ19_26340	ENOG4105HEI	LysR family (Transcriptional regulator
APZ19_26360	ENOG4105EE5	Membrane protein terC
APZ19_26365	ENOG4108M3R	transcriptional activator CadC
APZ19_26380	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
APZ19_26410	ENOG4105F87	Dehydratase
APZ19_26420	ENOG4105KWG	Pfam:DUF1696
APZ19_26435	ENOG4105ER2	Ompa motb domain protein
APZ19_26440	ENOG4107RD7	Flagellar Motor Protein, MotA
APZ19_26465	ENOG4105MQ3	flagellar protein FliS
APZ19_26470	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
APZ19_26480	ENOG4105I03	Flagellin
APZ19_26495	ENOG4105D00	flagellar biosynthetic protein flhB
APZ19_26500	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
APZ19_26505	ENOG4105VS8	Flagellar biosynthetic protein fliq
APZ19_26510	ENOG4105CN7	Flagellar biosynthetic protein FliP
APZ19_26515	ENOG4105DD5	Flagellar motor switch protein
APZ19_26530	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_26540	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
APZ19_26545	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
APZ19_26555	ENOG4108JIR	Flagellum-specific ATP synthase
APZ19_26565	ENOG4105BZU	Histidine kinase
APZ19_26580	ENOG4108EHX	EamA-like transporter family
APZ19_26605	ENOG4107SSZ	Phosphatase
APZ19_26625	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
APZ19_26630	ENOG4105EXG	Transcriptional regulator
APZ19_26650	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
APZ19_26670	ENOG4105BZU	Histidine kinase
APZ19_26675	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
APZ19_26680	ENOG4105CPQ	Dehydrogenase
APZ19_26740	ENOG4105D64	Mechanosensitive ion channel
APZ19_26755	ENOG4105DMF	Dehydrogenase
APZ19_26760	ENOG4105DAA	L-lactate
APZ19_26765	ENOG4105CC0	LysR family Transcriptional regulator
APZ19_26775	ENOG4108JQ5	ABC transporter
APZ19_26785	ENOG4105DAN	ATP-dependent protease
APZ19_26790	ENOG4108NVR	Methyl-accepting chemotaxis
APZ19_26795	ENOG4107QE9	Inherit from COG: Membrane
APZ19_26800	ENOG4105YE1	PilZ domain
APZ19_26815	ENOG4108MK9	spermidine N(1)-acetyltransferase
APZ19_26820	ENOG4108BGM	Quinol dehydrogenase periplasmic component
APZ19_26825	ENOG4105GXZ	Ferredoxin-type protein NapH
APZ19_26840	ENOG4105KBH	arsR family transcriptional regulator
APZ19_26845	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
APZ19_26850	ENOG4105XEP	YhcH YjgK YiaL family protein
APZ19_26865	ENOG4108JJB	ABC transporter
APZ19_26870	ENOG4108V7D	UPF0397 protein
APZ19_26875	ENOG4105EFX	secretion protein, HlyD family
APZ19_26880	ENOG4105KK7	inner membrane protein YiaW
APZ19_26890	ENOG4106TD9	Diguanylate cyclase
APZ19_26905	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
APZ19_26915	ENOG4107SEY	Conserved Protein
APZ19_26920	ENOG4108XDN	Transcriptional regulator
APZ19_26925	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
APZ19_26930	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
APZ19_26940	ENOG4105C1J	atp-dependent rna helicase
APZ19_26945	ENOG4105CUG	Oligopeptidase b
APZ19_26950	ENOG4107ENK	receptor
APZ19_26970	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
APZ19_26975	ENOG4107S17	Phosphate-binding protein
APZ19_26980	ENOG4105C8U	phosphate abc transporter
APZ19_26985	ENOG4105E2Z	phosphate ABC transporter (Permease
APZ19_26990	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
APZ19_27025	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
APZ19_27045	ENOG41069D7	Methyl-accepting chemotaxis
APZ19_27055	ENOG41086KC	Transcriptional regulator
APZ19_27060	ENOG41086KC	Transcriptional regulator
APZ19_27070	ENOG4108JJ6	Type I secretion system ATPase
APZ19_27080	ENOG4108UW5	maltose o-acetyltransferase
APZ19_27085	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
APZ19_27090	ENOG4105BZU	Histidine kinase
APZ19_27095	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
APZ19_27100	ENOG4105C8U	phosphate abc transporter
APZ19_27105	ENOG4105E2Z	phosphate ABC transporter (Permease
APZ19_27110	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
APZ19_27115	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
APZ19_27130	ENOG4105UYK	outer membrane protein a
APZ19_27150	ENOG4105KCK	Peptidoglycan-associated lipoprotein
APZ19_27160	ENOG4105BZU	Histidine kinase
APZ19_27165	ENOG4105CK1	PTS System
APZ19_27380	ENOG4105K5B	UPF0225 protein
APZ19_27405	ENOG4106V8H	Nucleoid-associated protein
APZ19_27430	ENOG4108WTW	DNA transposition protein
APZ19_27455	ENOG4105CK2	sodium dicarboxylate symporter
APZ19_27465	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
APZ19_27495	ENOG4105KK7	inner membrane protein YiaW
APZ19_27500	ENOG4105EFX	secretion protein, HlyD family
APZ19_27505	ENOG4105G2Y	Transcriptional regulator
APZ19_27515	ENOG4105EIP	mannose-6-phosphate isomerase
APZ19_27520	ENOG4105DM4	PTS System
APZ19_27525	ENOG4106R3P	AraC family transcriptional regulator
APZ19_27535	ENOG4108YRF	PTS System
APZ19_27540	ENOG4105DM4	PTS System
APZ19_27545	ENOG4105CBN	LysR family transcriptional regulator
APZ19_27555	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
APZ19_27560	ENOG4105CH6	catalase
APZ19_27570	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
APZ19_27575	ENOG4108WUH	Transcriptional regulator, TetR family
APZ19_27580	ENOG4105V0I	UPF0267 protein
APZ19_27615	ENOG4107TYR	Glycosyl Transferase
APZ19_27625	ENOG4105D75	Capsular exopolysaccharide family
APZ19_27640	ENOG4105D3Q	Sugar transferase
APZ19_27645	ENOG4108IJ9	(ABC) transporter
APZ19_27650	ENOG4107FKK	extracellular solute-binding protein family 1
APZ19_27655	ENOG4105D56	permease protein
APZ19_27660	ENOG4105EG2	ABC transporter, permease
APZ19_27690	ENOG4105CKW	Inner membrane protein yedI
APZ19_27695	ENOG4105EKE	dihydroorotase
APZ19_27710	ENOG4105QVC	MOSC domain-containing protein
APZ19_27710	ENOG4105QVC	MOSC domain-containing protein
APZ19_27715	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
APZ19_27720	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
APZ19_27760	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
APZ19_27765	ENOG4105EHG	Permease protein
APZ19_27775	ENOG4106GFD	transport protein
APZ19_27780	ENOG41090AP	transport protein
APZ19_27785	ENOG4105WQ5	TonB family
APZ19_27790	ENOG4105D4P	Coproporphyrinogen iii oxidase
APZ19_27795	ENOG41090JE	Utilization Protein
APZ19_27800	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
APZ19_27815	ENOG4107R88	Chemotaxis protein (CheV)
APZ19_27820	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
APZ19_27855	ENOG4105JQN	Transcriptional regulator
APZ19_27885	ENOG4105EJC	lysr family transcriptional regulator
APZ19_27900	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
APZ19_27905	ENOG4105G2Y	Transcriptional regulator
APZ19_27940	ENOG4108W2Y	isochorismatase
APZ19_27945	ENOG41063TF	transcriptional regulator (AraC
APZ19_27950	ENOG4105EP9	oxidoreductase
APZ19_27955	ENOG4105DIJ	Phosphoethanolamine transferase
APZ19_27960	ENOG41080IJ	Diacylglycerol kinase
APZ19_27970	ENOG4105JJR	Histidine kinase
APZ19_27975	ENOG4107EXC	regulatoR
APZ19_27980	ENOG4105C94	Transporter
APZ19_27985	ENOG4105DIA	mandelate racemase muconate lactonizing
APZ19_27990	ENOG4107EFR	Flavocytochrome c
APZ19_28000	ENOG4105EMU	Dehydrogenase
APZ19_28015	ENOG4108Z33	Thiol disulfide Interchange Protein
APZ19_28035	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
APZ19_28045	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
APZ19_28060	ENOG4105EST	Metal Dependent Phosphohydrolase
APZ19_28075	ENOG4105DZC	cytosine deaminase
APZ19_28080	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
APZ19_28085	ENOG4105CJW	magnesium transporter
APZ19_28090	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
APZ19_28095	ENOG4105EFX	secretion protein, HlyD family
APZ19_28120	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
APZ19_28125	ENOG4105E0F	Histidine kinase
APZ19_28155	ENOG4105DVH	amino acid
APZ19_28160	ENOG4105EW9	transcriptional regulator AsnC family
APZ19_28170	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
APZ19_28190	ENOG4105BZU	Histidine kinase
APZ19_28195	ENOG4105EE0	oxidoreductase
APZ19_28250	ENOG4108IYH	Dna topoisomerase
APZ19_28460	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
APZ19_28485	ENOG4107WZZ	SMC domain protein
APZ19_28550	ENOG4107U4J	modification
APZ19_28595	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
APZ19_28810	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
APZ19_28855	ENOG4107QJE	Chromosome Partitioning Protein
APZ19_28915	ENOG4105RWF	major outer membrane protein OmpA
APZ19_28955	ENOG4108RS6	transposase