locus-tag	class	description
APZ19_00015	COG0592	DNA-directed DNA polymerase activity
APZ19_00025	COG0187	DNA topoisomerase II activity
APZ19_00030	COG0071	Belongs to the small heat shock protein (HSP20) family
APZ19_00035	COG3977	Valine--pyruvate aminotransferase
APZ19_00055	COG4964	Belongs to the GSP D family
APZ19_00110	COG2205	protein histidine kinase activity
APZ19_00120	COG0366	Alpha amylase catalytic
APZ19_00135	COG2119	membrane
APZ19_00145	COG0425	Belongs to the sulfur carrier protein TusA family
APZ19_00160	COG0604	alcohol dehydrogenase
APZ19_00165	COG0183	Belongs to the thiolase family
APZ19_00175	COG1739	Uncharacterized protein family UPF0029
APZ19_00180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
APZ19_00225	COG2132	Multicopper oxidase
APZ19_00245	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
APZ19_00250	COG2104	thiamine diphosphate biosynthetic process
APZ19_00265	COG0006	proline dipeptidase activity
APZ19_00265	COG0006	proline dipeptidase activity
APZ19_00275	COG2814	Major facilitator Superfamily
APZ19_00295	COG3220	belongs to the UPF0276 family
APZ19_00305	COG0210	DNA helicase
APZ19_00315	COG0405	Gamma-glutamyltransferase
APZ19_00320	COG1280	lysine exporter protein (LysE YggA)
APZ19_00330	COG2962	Rard protein
APZ19_00335	COG0514	ATP-dependent DNA helicase (RecQ)
APZ19_00345	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
APZ19_00365	COG3118	belongs to the thioredoxin family
APZ19_00370	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
APZ19_00380	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
APZ19_00385	COG0633	Ferredoxin
APZ19_00435	COG2959	enzyme of heme biosynthesis
APZ19_00440	COG1587	Uroporphyrinogen-III synthase
APZ19_00450	COG3072	Adenylate cyclase
APZ19_00465	COG0019	diaminopimelate decarboxylase activity
APZ19_00485	COG1011	Hydrolase
APZ19_00490	COG3287	FIST C domain
APZ19_00490	COG2200	EAL domain
APZ19_00490	COG2199	diguanylate cyclase activity
APZ19_00510	COG0561	phosphatase activity
APZ19_00515	COG2267	carboxylic ester hydrolase activity
APZ19_00520	COG1280	lysine exporter protein (LysE YggA)
APZ19_00525	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
APZ19_00530	COG0640	Transcriptional regulator
APZ19_00535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
APZ19_00585	COG2095	MarC family integral membrane protein
APZ19_00595	COG0742	ribosomal rna small subunit methyltransferase
APZ19_00600	COG0552	protein localization to endoplasmic reticulum
APZ19_00600	COG0552	protein localization to endoplasmic reticulum
APZ19_00605	COG2884	Cell division ATP-binding protein ftsE
APZ19_00610	COG2177	Part of the ABC transporter FtsEX involved in
APZ19_00625	COG0705	Rhomboid family
APZ19_00630	COG1580	Controls the rotational direction of flagella during chemotaxis
APZ19_00635	COG3161	chorismate lyase activity
APZ19_00645	COG2937	Belongs to the GPAT DAPAT family
APZ19_00660	COG0534	Mate efflux family protein
APZ19_00765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APZ19_00775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
APZ19_00825	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
APZ19_00830	COG0250	Participates in transcription elongation, termination and antitermination
APZ19_00835	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
APZ19_00845	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
APZ19_00850	COG0222	ribosome binding
APZ19_00865	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
APZ19_00870	COG2816	NAD+ diphosphatase activity
APZ19_00880	COG1573	uracil-dna glycosylase
APZ19_00890	COG3068	Protein conserved in bacteria
APZ19_00895	COG1253	flavin adenine dinucleotide binding
APZ19_00910	COG0151	Belongs to the GarS family
APZ19_00920	COG0789	Transcriptional regulator
APZ19_00925	COG3710	Transcriptional regulator
APZ19_00930	COG0531	amino acid
APZ19_00935	COG1982	Orn Lys Arg decarboxylase major
APZ19_00980	COG3300	MHYT domain
APZ19_00980	COG5001	Diguanylate cyclase
APZ19_00985	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
APZ19_00990	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APZ19_01005	COG0439	Biotin carboxylase
APZ19_01010	COG0511	ligase activity, forming carbon-carbon bonds
APZ19_01015	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
APZ19_01020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
APZ19_01035	COG2814	Major facilitator Superfamily
APZ19_01040	COG2205	protein histidine kinase activity
APZ19_01040	COG2198	Histidine kinase
APZ19_01040	COG0784	Response regulator, receiver
APZ19_01060	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APZ19_01070	COG2095	MarC family integral membrane protein
APZ19_01080	COG4232	protein-disulfide reductase activity
APZ19_01085	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
APZ19_01090	COG1027	Aspartate ammonia-lyase
APZ19_01095	COG3030	protein affecting phage T7 exclusion by the F plasmid
APZ19_01100	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
APZ19_01110	COG2205	protein histidine kinase activity
APZ19_01115	COG0745	RESPONSE REGULATOR receiver
APZ19_01120	COG3678	ATP-independent chaperone mediated protein folding
APZ19_01125	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
APZ19_01135	COG0534	Mate efflux family protein
APZ19_01160	COG1509	lysine 2,3-aminomutase activity
APZ19_01165	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
APZ19_01190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
APZ19_01195	COG1053	succinate dehydrogenase
APZ19_01220	COG4942	peptidase
APZ19_01225	COG1045	serine acetyltransferase
APZ19_01235	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
APZ19_01240	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APZ19_01245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
APZ19_01255	COG0840	transmembrane signaling receptor activity
APZ19_01260	COG0471	metal ion transport
APZ19_01275	COG1162	GTPase activity
APZ19_01280	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
APZ19_01355	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
APZ19_01360	COG0802	atpase or kinase
APZ19_01365	COG0860	N-Acetylmuramoyl-L-alanine amidase
APZ19_01370	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
APZ19_01385	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
APZ19_01390	COG0330	HflC and HflK could
APZ19_01395	COG0330	HflC and HflK could
APZ19_01400	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
APZ19_01405	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
APZ19_01415	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
APZ19_01420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
APZ19_01420	COG1017	nitric oxide dioxygenase activity
APZ19_01430	COG0557	exoribonuclease II activity
APZ19_01435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APZ19_01440	COG0546	phosphoglycolate phosphatase activity
APZ19_01455	COG0512	Glutamine amidotransferase of anthranilate synthase
APZ19_01460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
APZ19_01480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
APZ19_01485	COG3954	Phosphoribulokinase
APZ19_01495	COG0429	hydrolase of the alpha beta-hydrolase fold
APZ19_01505	COG0488	(ABC) transporter
APZ19_01515	COG2249	NAD(P)H dehydrogenase (quinone) activity
APZ19_01530	COG1047	Peptidyl-prolyl cis-trans
APZ19_01540	COG1446	asparaginase
APZ19_01555	COG0545	Peptidyl-prolyl cis-trans isomerase
APZ19_01560	COG2964	Protein conserved in bacteria
APZ19_01565	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
APZ19_01570	COG2923	Belongs to the DsrF TusC family
APZ19_01575	COG2168	tRNA wobble position uridine thiolation
APZ19_01590	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APZ19_01600	COG2906	2 iron, 2 sulfur cluster binding
APZ19_01610	COG0281	malic enzyme
APZ19_01620	COG0626	cystathionine gamma-synthase activity
APZ19_01625	COG0460	homoserine dehydrogenase
APZ19_01625	COG0527	aspartate kinase activity
APZ19_01630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
APZ19_01640	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
APZ19_01650	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
APZ19_01665	COG0165	Argininosuccinate lyase
APZ19_01665	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
APZ19_01680	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
APZ19_01685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
APZ19_01685	COG0678	peroxiredoxin activity
APZ19_01695	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
APZ19_01740	COG0338	D12 class N6 adenine-specific DNA methyltransferase
APZ19_01745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
APZ19_01755	COG2965	DNA replication, synthesis of RNA primer
APZ19_01775	COG0305	Participates in initiation and elongation during chromosome replication
APZ19_01780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
APZ19_01790	COG0432	Pfam Uncharacterised protein family UPF0047
APZ19_01805	COG0735	belongs to the Fur family
APZ19_01810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APZ19_01830	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
APZ19_01895	COG1410	methionine synthase
APZ19_01895	COG0646	methionine synthase
APZ19_01900	COG0527	aspartate kinase activity
APZ19_01905	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
APZ19_01915	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
APZ19_01930	COG0629	single-stranded DNA binding
APZ19_01935	COG2199	diguanylate cyclase activity
APZ19_01935	COG2200	EAL domain
APZ19_01960	COG3267	Type II secretory pathway component ExeA
APZ19_01960	COG3409	Peptidoglycan-binding domain 1 protein
APZ19_01970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APZ19_01975	COG1459	type II secretion system
APZ19_02020	COG1077	Cell shape determining protein MreB Mrl
APZ19_02025	COG1792	Involved in formation and maintenance of cell shape
APZ19_02030	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
APZ19_02035	COG0424	maF-like protein
APZ19_02040	COG1530	ribonuclease E activity
APZ19_02045	COG3164	Protein of unknown function
APZ19_02050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
APZ19_02055	COG0312	modulator of DNA gyrase
APZ19_02060	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
APZ19_02075	COG0564	pseudouridine synthase activity
APZ19_02080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APZ19_02085	COG3028	Belongs to the UPF0307 family
APZ19_02090	COG0312	modulator of DNA gyrase
APZ19_02095	COG2239	Acts as a magnesium transporter
APZ19_02100	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
APZ19_02110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APZ19_02115	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APZ19_02125	COG1137	ATPase activity
APZ19_02130	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
APZ19_02140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
APZ19_02140	COG0517	IMP dehydrogenase activity
APZ19_02150	COG1127	ABC transporter
APZ19_02155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
APZ19_02160	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
APZ19_02165	COG2854	intermembrane phospholipid transfer
APZ19_02175	COG5007	Belongs to the BolA IbaG family
APZ19_02185	COG0204	Acyl-transferase
APZ19_02190	COG0251	oxidation-reduction process
APZ19_02240	COG0525	valine-tRNA ligase activity
APZ19_02245	COG2927	DNA polymerase III (CHI subunit)
APZ19_02255	COG0795	lipopolysaccharide-transporting ATPase activity
APZ19_02260	COG0795	lipopolysaccharide-transporting ATPase activity
APZ19_02270	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_02280	COG0726	polysaccharide deacetylase
APZ19_02285	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
APZ19_02295	COG1447	Phosphotransferase system cellobiose-specific component IIA
APZ19_02300	COG1486	melibiose metabolic process
APZ19_02315	COG3437	response regulator, receiver
APZ19_02370	COG1012	belongs to the aldehyde dehydrogenase family
APZ19_02470	COG0635	Involved in the biosynthesis of porphyrin-containing compound
APZ19_02475	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
APZ19_02490	COG0762	integral membrane protein
APZ19_02495	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
APZ19_02500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
APZ19_02515	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
APZ19_02520	COG1678	Uncharacterized ACR, COG1678
APZ19_02525	COG0189	ligase activity
APZ19_02530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
APZ19_02535	COG2356	endonuclease I
APZ19_02550	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
APZ19_02555	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APZ19_02575	COG0191	fructose-bisphosphate aldolase activity
APZ19_02580	COG0668	transmembrane transport
APZ19_02595	COG0583	DNA-binding transcription factor activity
APZ19_02605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
APZ19_02615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
APZ19_02625	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
APZ19_02640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
APZ19_02645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
APZ19_02665	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
APZ19_02675	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
APZ19_02685	COG1595	DNA-templated transcription, initiation
APZ19_02695	COG3026	antisigma factor binding
APZ19_02700	COG3086	response to oxidative stress
APZ19_02710	COG0681	Belongs to the peptidase S26 family
APZ19_02720	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
APZ19_02725	COG1381	Involved in DNA repair and RecF pathway recombination
APZ19_02730	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
APZ19_02750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APZ19_02755	COG3956	TIGRFAM MazG family protein
APZ19_02765	COG0148	phosphopyruvate hydratase activity
APZ19_02775	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
APZ19_02805	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APZ19_02815	COG1546	Belongs to the CinA family
APZ19_02820	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
APZ19_02835	COG0527	aspartate kinase activity
APZ19_02915	COG5016	pyruvate
APZ19_02915	COG0511	ligase activity, forming carbon-carbon bonds
APZ19_02920	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
APZ19_02930	COG1238	metal cluster binding
APZ19_02935	COG0612	Peptidase, M16
APZ19_02955	COG4536	flavin adenine dinucleotide binding
APZ19_02960	COG4137	Cytochrome C assembly protein
APZ19_02965	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
APZ19_02970	COG0228	four-way junction DNA binding
APZ19_02985	COG0335	large ribosomal subunit rRNA binding
APZ19_02990	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
APZ19_02995	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
APZ19_03000	COG0237	dephospho-CoA kinase activity
APZ19_03010	COG1459	type II secretion system
APZ19_03015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APZ19_03035	COG2186	Transcriptional regulator
APZ19_03040	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
APZ19_03045	COG0508	dehydrogenase complex catalyzes the overall conversion of
APZ19_03050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
APZ19_03065	COG0288	reversible hydration of carbon dioxide
APZ19_03070	COG0659	secondary active sulfate transmembrane transporter activity
APZ19_03075	COG1131	(ABC) transporter
APZ19_03080	COG0842	Transport permease protein
APZ19_03085	COG1560	Kdo2-lipid A biosynthetic process
APZ19_03100	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APZ19_03110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
APZ19_03115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
APZ19_03125	COG1643	Atp-dependent helicase
APZ19_03130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
APZ19_03135	COG1752	Esterase of the alpha-beta hydrolase superfamily
APZ19_03140	COG1049	propionate catabolic process, 2-methylcitrate cycle
APZ19_03155	COG0004	ammonium transporteR
APZ19_03160	COG1840	ABC-type Fe3 transport system, periplasmic component
APZ19_03175	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APZ19_03190	COG2971	BadF BadG BcrA BcrD
APZ19_03200	COG4608	Belongs to the ABC transporter superfamily
APZ19_03205	COG0444	Belongs to the ABC transporter superfamily
APZ19_03210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
APZ19_03220	COG0747	negative chemotaxis
APZ19_03235	COG0628	permease
APZ19_03255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APZ19_03260	COG0739	heme binding
APZ19_03265	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APZ19_03275	COG2027	D-alanyl-D-alanine carboxypeptidase
APZ19_03280	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
APZ19_03285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
APZ19_03290	COG1534	Rna-binding protein
APZ19_03300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
APZ19_03305	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
APZ19_03315	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
APZ19_03335	COG0195	Participates in both transcription termination and antitermination
APZ19_03355	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
APZ19_03375	COG0534	Mate efflux family protein
APZ19_03400	COG3153	acetyltransferase
APZ19_03420	COG3706	GGDEF domain
APZ19_03430	COG0084	hydrolase, TatD family'
APZ19_03435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APZ19_03445	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
APZ19_03455	COG0813	purine-nucleoside phosphorylase activity
APZ19_03465	COG0560	Phosphoserine phosphatase
APZ19_03475	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
APZ19_03480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APZ19_03485	COG0583	DNA-binding transcription factor activity
APZ19_03520	COG1022	Amp-dependent synthetase and ligase
APZ19_03525	COG0741	lytic transglycosylase activity
APZ19_03550	COG4964	Belongs to the GSP D family
APZ19_03610	COG0583	DNA-binding transcription factor activity
APZ19_03615	COG3408	Glycogen debranching enzyme
APZ19_03615	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
APZ19_03625	COG0531	amino acid
APZ19_03630	COG2731	YhcH YjgK YiaL family protein
APZ19_03635	COG3250	beta-galactosidase activity
APZ19_03640	COG1609	Transcriptional regulator
APZ19_03645	COG0768	penicillin binding
APZ19_03650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
APZ19_03655	COG1085	galactose-1-phosphate uridylyltransferase
APZ19_03665	COG2017	converts alpha-aldose to the beta-anomer
APZ19_03670	COG1609	Transcriptional regulator
APZ19_03675	COG1263	PTS System
APZ19_03675	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APZ19_03685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APZ19_03705	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
APZ19_03710	COG1349	DNA-binding transcription factor activity
APZ19_03720	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
APZ19_03730	COG2271	Major facilitator Superfamily
APZ19_03735	COG0584	glycerophosphoryl diester phosphodiesterase
APZ19_03750	COG2171	N-acyltransferase activity
APZ19_03765	COG3141	response to X-ray
APZ19_03785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
APZ19_03790	COG1074	ATP-dependent DNA helicase activity
APZ19_03795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
APZ19_03810	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
APZ19_03810	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
APZ19_03820	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
APZ19_03825	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
APZ19_03830	COG2166	iron-sulfur cluster assembly
APZ19_03835	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
APZ19_03840	COG0693	protein deglycase activity
APZ19_03845	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
APZ19_03850	COG3248	Nucleoside-binding outer membrane protein
APZ19_03870	COG1595	DNA-templated transcription, initiation
APZ19_03900	COG0271	Belongs to the BolA IbaG family
APZ19_03925	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
APZ19_03935	COG1477	protein flavinylation
APZ19_03945	COG3706	GGDEF domain
APZ19_03945	COG0745	RESPONSE REGULATOR receiver
APZ19_03950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
APZ19_03955	COG0514	ATP-dependent DNA helicase (RecQ)
APZ19_03960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
APZ19_03975	COG0733	neurotransmitter:sodium symporter activity
APZ19_04000	COG1720	tRNA m6t6A37 methyltransferase activity
APZ19_04015	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
APZ19_04050	COG3098	single-species biofilm formation
APZ19_04055	COG0564	pseudouridine synthase activity
APZ19_04070	COG0024	Methionine aminopeptidase
APZ19_04095	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
APZ19_04100	COG0575	Belongs to the CDS family
APZ19_04110	COG0750	zinc metalloprotease
APZ19_04120	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
APZ19_04125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
APZ19_04150	COG0587	DNA-directed DNA polymerase activity
APZ19_04170	COG0347	Belongs to the P(II) protein family
APZ19_04185	COG1388	LysM domain
APZ19_04185	COG0741	lytic transglycosylase activity
APZ19_04195	COG2226	methyltransferase
APZ19_04205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
APZ19_04225	COG1960	acyl-CoA dehydrogenase activity
APZ19_04230	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
APZ19_04235	COG0121	glutamine amidotransferase
APZ19_04240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
APZ19_04245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
APZ19_04250	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
APZ19_04255	COG2233	PERMEase
APZ19_04275	COG1393	Belongs to the ArsC family
APZ19_04280	COG4783	chaperone-mediated protein folding
APZ19_04295	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
APZ19_04300	COG2716	regulation of RNA biosynthetic process
APZ19_04305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
APZ19_04330	COG1393	Belongs to the ArsC family
APZ19_04355	COG2837	iron assimilation
APZ19_04360	COG2169	Transcriptional regulator
APZ19_04365	COG1486	melibiose metabolic process
APZ19_04380	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APZ19_04390	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APZ19_04395	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APZ19_04400	COG1334	flagellar protein FlaG
APZ19_04405	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
APZ19_04415	COG1516	flagellar protein fliS
APZ19_04420	COG2204	response regulator
APZ19_04425	COG4191	Histidine kinase
APZ19_04430	COG2204	response regulator
APZ19_04435	COG1677	Flagellar hook-basal body complex protein FliE
APZ19_04445	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
APZ19_04500	COG1987	bacterial-type flagellum assembly
APZ19_04505	COG1684	flagellar biosynthetic protein fliR
APZ19_04525	COG0455	bacterial-type flagellum organization
APZ19_04540	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
APZ19_04545	COG0643	Histidine kinase
APZ19_04545	COG2198	Histidine kinase
APZ19_04550	COG2201	protein-glutamate methylesterase activity
APZ19_04555	COG1192	Involved in chromosome partitioning
APZ19_04565	COG0835	chemotaxis
APZ19_04575	COG4133	protoheme IX ABC transporter activity
APZ19_04580	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
APZ19_04585	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
APZ19_04600	COG1138	Cytochrome C-type biogenesis protein
APZ19_04605	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
APZ19_04615	COG3088	subunit of a heme lyase
APZ19_04615	COG4235	cytochrome complex assembly
APZ19_04620	COG2853	Lipoprotein
APZ19_04625	COG2067	long-chain fatty acid transport protein
APZ19_04630	COG2067	long-chain fatty acid transport protein
APZ19_04645	COG0183	Belongs to the thiolase family
APZ19_04660	COG2062	phosphohistidine phosphatase, SixA
APZ19_04665	COG2840	Smr protein MutS2
APZ19_04670	COG2890	protein-(glutamine-N5) methyltransferase activity
APZ19_04680	COG2860	membrane
APZ19_04685	COG3101	peptidyl-lysine hydroxylation
APZ19_04705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
APZ19_04710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
APZ19_04715	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APZ19_04735	COG0285	dihydrofolate synthase activity
APZ19_04740	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
APZ19_04745	COG1286	toxin biosynthetic process
APZ19_04750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
APZ19_04755	COG0583	DNA-binding transcription factor activity
APZ19_04760	COG0745	RESPONSE REGULATOR receiver
APZ19_04770	COG2832	Protein of unknown function (DUF454)
APZ19_04780	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
APZ19_04790	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
APZ19_04795	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
APZ19_04800	COG0814	amino acid
APZ19_04805	COG0251	oxidation-reduction process
APZ19_04815	COG2964	Protein conserved in bacteria
APZ19_04830	COG2983	Belongs to the UPF0260 family
APZ19_04835	COG2261	transglycosylase associated protein
APZ19_04840	COG2985	domain, Protein
APZ19_04845	COG0076	glutamate decarboxylase activity
APZ19_04850	COG0668	transmembrane transport
APZ19_04860	COG0346	lactoylglutathione lyase activity
APZ19_04870	COG1785	Belongs to the alkaline phosphatase family
APZ19_04885	COG2226	methyltransferase
APZ19_04910	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
APZ19_04915	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APZ19_04925	COG3139	Protein of unknown function (DUF1315)
APZ19_04930	COG0252	asparaginase activity
APZ19_04935	COG0616	signal peptide processing
APZ19_04940	COG0446	pyridine nucleotide-disulphide oxidoreductase
APZ19_04940	COG1902	pentaerythritol trinitrate reductase activity
APZ19_04945	COG0778	Nitroreductase
APZ19_04950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APZ19_04965	COG0123	including yeast histone deacetylase and acetoin utilization protein
APZ19_04970	COG4269	membrane
APZ19_04985	COG3083	sulfuric ester hydrolase activity
APZ19_05010	COG1757	Na H antiporter
APZ19_05015	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
APZ19_05025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
APZ19_05030	COG2095	MarC family integral membrane protein
APZ19_05035	COG1454	alcohol dehydrogenase
APZ19_05035	COG1012	belongs to the aldehyde dehydrogenase family
APZ19_05055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
APZ19_05060	COG4974	Belongs to the 'phage' integrase family
APZ19_05115	COG2885	chlorophyll binding
APZ19_05115	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
APZ19_05170	COG2003	Belongs to the UPF0758 family
APZ19_05245	COG3504	Conjugal transfer protein
APZ19_05270	COG3451	type IV secretory pathway VirB4
APZ19_05305	COG2056	Na+-H+ antiporter family
APZ19_05315	COG2885	chlorophyll binding
APZ19_05325	COG0346	lactoylglutathione lyase activity
APZ19_05330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
APZ19_05335	COG4660	Part of a membrane complex involved in electron transport
APZ19_05340	COG4659	FMN binding
APZ19_05345	COG4658	electron transport chain
APZ19_05350	COG4656	Part of a membrane complex involved in electron transport
APZ19_05360	COG4657	Part of a membrane complex involved in electron transport
APZ19_05365	COG1882	Formate acetyltransferase
APZ19_05380	COG0556	nucleotide-excision repair
APZ19_05395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
APZ19_05400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
APZ19_05405	COG0521	Mo-molybdopterin cofactor biosynthetic process
APZ19_05415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
APZ19_05420	COG0314	molybdopterin synthase activity
APZ19_05430	COG0601	transmembrane transport
APZ19_05435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
APZ19_05440	COG0444	Belongs to the ABC transporter superfamily
APZ19_05450	COG0435	Glutathione S-transferase
APZ19_05455	COG3174	membrane
APZ19_05465	COG0857	belongs to the CobB CobQ family
APZ19_05465	COG0280	phosphate acetyltransferase
APZ19_05485	COG4120	Belongs to the binding-protein-dependent transport system permease family
APZ19_05490	COG1122	ATPase activity
APZ19_05495	COG0366	Alpha amylase catalytic
APZ19_05505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
APZ19_05510	COG3012	SEC-C Motif Domain Protein
APZ19_05510	COG3318	Belongs to the UPF0149 family
APZ19_05515	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
APZ19_05525	COG2186	Transcriptional regulator
APZ19_05570	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
APZ19_05575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
APZ19_05580	COG0659	secondary active sulfate transmembrane transporter activity
APZ19_05585	COG1530	ribonuclease E activity
APZ19_05590	COG0564	pseudouridine synthase activity
APZ19_05595	COG0424	maF-like protein
APZ19_05600	COG1399	metal-binding, possibly nucleic acid-binding protein
APZ19_05615	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APZ19_05645	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
APZ19_05660	COG0084	hydrolase, TatD family'
APZ19_05665	COG1263	PTS System
APZ19_05665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APZ19_05680	COG0733	neurotransmitter:sodium symporter activity
APZ19_05695	COG4667	esterase of the alpha-beta hydrolase superfamily
APZ19_05705	COG1940	carbohydrate kinase activity
APZ19_05710	COG0835	chemotaxis
APZ19_05710	COG0784	Response regulator, receiver
APZ19_05730	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_05735	COG0616	signal peptide processing
APZ19_05745	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
APZ19_05750	COG0539	negative regulation of cytoplasmic translation
APZ19_05760	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
APZ19_05765	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
APZ19_05775	COG4166	transmembrane transport
APZ19_05835	COG3119	arylsulfatase activity
APZ19_05840	COG1309	transcriptional regulator
APZ19_05845	COG3009	Protein conserved in bacteria
APZ19_05850	COG3008	intermembrane lipid transfer
APZ19_05850	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
APZ19_05855	COG2995	paraquat-inducible protein a
APZ19_05860	COG1609	Transcriptional regulator
APZ19_05865	COG3258	Cytochrome c
APZ19_05870	COG2863	cytochrome
APZ19_05900	COG3250	beta-galactosidase activity
APZ19_05910	COG4580	involved in the transport of maltose and maltodextrins
APZ19_05920	COG2211	Major facilitator Superfamily
APZ19_05925	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
APZ19_05940	COG4232	protein-disulfide reductase activity
APZ19_05945	COG3118	belongs to the thioredoxin family
APZ19_05955	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
APZ19_05965	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APZ19_05975	COG3153	acetyltransferase
APZ19_06015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APZ19_06025	COG0577	efflux transmembrane transporter activity
APZ19_06025	COG1136	(ABC) transporter
APZ19_06030	COG0577	efflux transmembrane transporter activity
APZ19_06030	COG1136	(ABC) transporter
APZ19_06035	COG0577	efflux transmembrane transporter activity
APZ19_06035	COG1136	(ABC) transporter
APZ19_06045	COG2176	DNA-directed DNA polymerase activity
APZ19_06060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
APZ19_06115	COG5002	protein histidine kinase activity
APZ19_06115	COG3850	Histidine kinase
APZ19_06120	COG0745	RESPONSE REGULATOR receiver
APZ19_06125	COG0463	Glycosyl transferase, family 2
APZ19_06130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
APZ19_06140	COG0840	transmembrane signaling receptor activity
APZ19_06145	COG2964	Protein conserved in bacteria
APZ19_06160	COG0446	pyridine nucleotide-disulphide oxidoreductase
APZ19_06180	COG1032	radical SAM domain protein
APZ19_06185	COG2203	Gaf domain
APZ19_06185	COG5001	Diguanylate cyclase
APZ19_06185	COG3706	GGDEF domain
APZ19_06185	COG4251	negative regulation of phosphorylation
APZ19_06200	COG0583	DNA-binding transcription factor activity
APZ19_06215	COG2350	Protein conserved in bacteria
APZ19_06220	COG1607	acyl-coa hydrolase
APZ19_06245	COG1301	dicarboxylic acid transport
APZ19_06250	COG0159	tryptophan synthase activity
APZ19_06260	COG0135	phosphoribosylanthranilate isomerase activity
APZ19_06260	COG0134	indole-3-glycerol-phosphate synthase activity
APZ19_06270	COG0512	Glutamine amidotransferase of anthranilate synthase
APZ19_06275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APZ19_06285	COG0613	PHP domain protein
APZ19_06290	COG0009	L-threonylcarbamoyladenylate synthase
APZ19_06300	COG1187	pseudouridine synthase activity
APZ19_06320	COG0417	DNA replication proofreading
APZ19_06325	COG2197	response regulator
APZ19_06330	COG0322	excinuclease ABC activity
APZ19_06370	COG0019	diaminopimelate decarboxylase activity
APZ19_06395	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APZ19_06400	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APZ19_06405	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
APZ19_06425	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
APZ19_06435	COG0437	4 iron, 4 sulfur cluster binding
APZ19_06440	COG3301	Polysulphide reductase, NrfD
APZ19_06445	COG1138	Cytochrome C-type biogenesis protein
APZ19_06455	COG4235	cytochrome complex assembly
APZ19_06455	COG3088	subunit of a heme lyase
APZ19_06465	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
APZ19_06490	COG2989	Protein conserved in bacteria
APZ19_06495	COG3108	Peptidase M15
APZ19_06500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
APZ19_06515	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
APZ19_06540	COG1846	Transcriptional regulator
APZ19_06545	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
APZ19_06550	COG0840	transmembrane signaling receptor activity
APZ19_06570	COG1448	Aminotransferase
APZ19_06575	COG2770	Histidine kinase
APZ19_06575	COG3437	response regulator, receiver
APZ19_06580	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APZ19_06590	COG1609	Transcriptional regulator
APZ19_06605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
APZ19_06620	COG0017	Asparaginyl-tRNA synthetase
APZ19_06630	COG0720	synthase
APZ19_06635	COG2197	response regulator
APZ19_06645	COG5001	Diguanylate cyclase
APZ19_06645	COG3300	MHYT domain
APZ19_06650	COG1760	l-serine dehydratase
APZ19_06655	COG0814	amino acid
APZ19_06670	COG0784	Response regulator, receiver
APZ19_06670	COG2205	protein histidine kinase activity
APZ19_06675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
APZ19_06690	COG3106	COG3106 Predicted ATPase
APZ19_06705	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APZ19_06910	COG2801	Transposase and inactivated derivatives
APZ19_07290	COG1403	HNH endonuclease
APZ19_07380	COG2801	Transposase and inactivated derivatives
APZ19_07440	COG1733	regulation of RNA biosynthetic process
APZ19_07450	COG3340	Belongs to the peptidase S51 family
APZ19_07465	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APZ19_07490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
APZ19_07495	COG1609	Transcriptional regulator
APZ19_07535	COG0456	acetyltransferase
APZ19_07540	COG0471	metal ion transport
APZ19_07545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APZ19_07545	COG4191	Histidine kinase
APZ19_07555	COG5001	Diguanylate cyclase
APZ19_07555	COG3300	MHYT domain
APZ19_07565	COG1280	lysine exporter protein (LysE YggA)
APZ19_07570	COG1328	CTP reductase activity
APZ19_07575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APZ19_07585	COG0861	Integral membrane protein TerC family
APZ19_07595	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
APZ19_07605	COG3706	GGDEF domain
APZ19_07620	COG0814	amino acid
APZ19_07640	COG1132	(ABC) transporter
APZ19_07645	COG1132	(ABC) transporter
APZ19_07660	COG0583	DNA-binding transcription factor activity
APZ19_07685	COG0443	Heat shock 70 kDa protein
APZ19_07690	COG0443	Heat shock 70 kDa protein
APZ19_07700	COG3706	GGDEF domain
APZ19_07725	COG3227	Zinc metalloprotease (Elastase)
APZ19_07735	COG0243	molybdopterin cofactor binding
APZ19_07740	COG0437	4 iron, 4 sulfur cluster binding
APZ19_07745	COG3302	dmso reductase anchor subunit
APZ19_07760	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
APZ19_07765	COG1643	Atp-dependent helicase
APZ19_07790	COG3063	Type IV pilus biogenesis stability protein PilW
APZ19_07825	COG0531	amino acid
APZ19_07830	COG1280	lysine exporter protein (LysE YggA)
APZ19_07835	COG0583	DNA-binding transcription factor activity
APZ19_07840	COG0702	epimerase
APZ19_07845	COG0583	DNA-binding transcription factor activity
APZ19_07850	COG1560	Kdo2-lipid A biosynthetic process
APZ19_07865	COG1846	Transcriptional regulator
APZ19_07880	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
APZ19_07885	COG1280	lysine exporter protein (LysE YggA)
APZ19_07915	COG1115	amino acid carrier protein
APZ19_07970	COG0583	DNA-binding transcription factor activity
APZ19_07975	COG1368	sulfuric ester hydrolase activity
APZ19_07980	COG0215	cysteine-tRNA ligase activity
APZ19_07985	COG0534	Mate efflux family protein
APZ19_07990	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
APZ19_08000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
APZ19_08005	COG0456	acetyltransferase
APZ19_08010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
APZ19_08015	COG0662	Cupin 2, conserved barrel domain protein
APZ19_08020	COG0527	aspartate kinase activity
APZ19_08035	COG0583	DNA-binding transcription factor activity
APZ19_08040	COG1858	cytochrome C peroxidase
APZ19_08045	COG1404	Belongs to the peptidase S8 family
APZ19_08050	COG0583	DNA-binding transcription factor activity
APZ19_08070	COG2169	Transcriptional regulator
APZ19_08075	COG0697	spore germination
APZ19_08080	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
APZ19_08085	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
APZ19_08095	COG0583	DNA-binding transcription factor activity
APZ19_08100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
APZ19_08120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APZ19_08135	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
APZ19_08140	COG3290	protein histidine kinase activity
APZ19_08145	COG4565	transcriptional regulatory protein
APZ19_08150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
APZ19_08155	COG0363	glucosamine-6-phosphate deaminase activity
APZ19_08160	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
APZ19_08190	COG3284	Transcriptional regulator
APZ19_08195	COG1012	belongs to the aldehyde dehydrogenase family
APZ19_08200	COG1902	pentaerythritol trinitrate reductase activity
APZ19_08210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APZ19_08220	COG0840	transmembrane signaling receptor activity
APZ19_08225	COG0730	response to heat
APZ19_08260	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
APZ19_08265	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
APZ19_08360	COG3501	Rhs element vgr protein
APZ19_08375	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
APZ19_08380	COG0372	Belongs to the citrate synthase family
APZ19_08385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
APZ19_08390	COG2828	Protein conserved in bacteria
APZ19_08415	COG0561	phosphatase activity
APZ19_08420	COG0602	queuosine metabolic process
APZ19_08430	COG3706	GGDEF domain
APZ19_08480	COG1254	Belongs to the acylphosphatase family
APZ19_08485	COG2920	part of a sulfur-relay system
APZ19_08495	COG0670	Belongs to the BI1 family
APZ19_08500	COG1126	abc transporter atp-binding protein
APZ19_08505	COG0765	amino acid transport
APZ19_08510	COG4597	amino acid ABC transporter
APZ19_08515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APZ19_08530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
APZ19_08555	COG3008	intermembrane lipid transfer
APZ19_08560	COG2995	paraquat-inducible protein a
APZ19_08565	COG1132	(ABC) transporter
APZ19_08570	COG1956	GAF domain-containing protein
APZ19_08575	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
APZ19_08580	COG0793	Belongs to the peptidase S41A family
APZ19_08590	COG0308	aminopeptidase N
APZ19_08600	COG2902	Dehydrogenase
APZ19_08645	COG1067	ATP-dependent peptidase activity
APZ19_08675	COG2205	protein histidine kinase activity
APZ19_08675	COG0784	Response regulator, receiver
APZ19_08690	COG3278	Belongs to the heme-copper respiratory oxidase family
APZ19_08705	COG2010	Cytochrome c
APZ19_08715	COG2217	Heavy metal translocating P-type atpase
APZ19_08730	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
APZ19_08735	COG0589	response to stress
APZ19_08760	COG3842	ATPase activity
APZ19_08765	COG1176	ABC-type spermidine putrescine transport system, permease component I
APZ19_08770	COG1177	transmembrane transport
APZ19_08775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
APZ19_08780	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
APZ19_08785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
APZ19_08800	COG0437	4 iron, 4 sulfur cluster binding
APZ19_08805	COG0243	molybdopterin cofactor binding
APZ19_08805	COG3383	formate dehydrogenase (NAD+) activity
APZ19_08815	COG3381	protein complex oligomerization
APZ19_08835	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
APZ19_08840	COG0488	(ABC) transporter
APZ19_08860	COG4191	Histidine kinase
APZ19_08865	COG2204	response regulator
APZ19_08875	COG4662	Binding-protein-dependent transport system inner membrane component
APZ19_08880	COG3842	ATPase activity
APZ19_08890	COG0303	'Molybdopterin
APZ19_08905	COG1940	carbohydrate kinase activity
APZ19_08955	COG0840	transmembrane signaling receptor activity
APZ19_08960	COG0791	NLP P60 protein
APZ19_08970	COG3706	GGDEF domain
APZ19_08975	COG2201	protein-glutamate methylesterase activity
APZ19_08990	COG0307	riboflavin synthase, alpha
APZ19_08995	COG0534	Mate efflux family protein
APZ19_09005	COG1793	dna ligase
APZ19_09015	COG2885	chlorophyll binding
APZ19_09035	COG2204	response regulator
APZ19_09045	COG0438	transferase activity, transferring glycosyl groups
APZ19_09085	COG0297	glycogen (starch) synthase activity
APZ19_09090	COG1215	transferase activity, transferring glycosyl groups
APZ19_09095	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
APZ19_09105	COG3064	Membrane
APZ19_09130	COG5001	Diguanylate cyclase
APZ19_09130	COG3300	MHYT domain
APZ19_09135	COG3850	Histidine kinase
APZ19_09135	COG4999	Histidine kinase
APZ19_09135	COG3437	response regulator, receiver
APZ19_09135	COG2205	protein histidine kinase activity
APZ19_09155	COG0110	maltose O-acetyltransferase activity
APZ19_09325	COG0860	N-Acetylmuramoyl-L-alanine amidase
APZ19_09325	COG3409	Peptidoglycan-binding domain 1 protein
APZ19_09385	COG3081	Nucleoid-associated protein
APZ19_09415	COG2842	Transposition protein
APZ19_09440	COG1846	Transcriptional regulator
APZ19_09455	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
APZ19_09460	COG3247	response to pH
APZ19_09465	COG0668	transmembrane transport
APZ19_09480	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
APZ19_09495	COG0745	RESPONSE REGULATOR receiver
APZ19_09560	COG0519	Catalyzes the synthesis of GMP from XMP
APZ19_09565	COG0589	response to stress
APZ19_09580	COG1454	alcohol dehydrogenase
APZ19_09585	COG0235	Class ii aldolase
APZ19_09590	COG4154	Belongs to the RbsD FucU family
APZ19_09595	COG1070	Carbohydrate kinase
APZ19_09600	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
APZ19_09605	COG0738	Major facilitator superfamily
APZ19_09610	COG1349	DNA-binding transcription factor activity
APZ19_09625	COG2197	response regulator
APZ19_09640	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
APZ19_09645	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
APZ19_09650	COG3051	citrate lyase alpha subunit
APZ19_09655	COG2301	Belongs to the HpcH HpaI aldolase family
APZ19_09660	COG3052	prosthetic group binding
APZ19_09665	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
APZ19_09675	COG3630	sodium ion export across plasma membrane
APZ19_09680	COG0511	ligase activity, forming carbon-carbon bonds
APZ19_09680	COG5016	pyruvate
APZ19_09685	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
APZ19_09695	COG4565	transcriptional regulatory protein
APZ19_09720	COG0657	acetylesterase activity
APZ19_09730	COG0625	glutathione transferase activity
APZ19_09740	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
APZ19_09755	COG2195	Cleaves the N-terminal amino acid of tripeptides
APZ19_09765	COG3706	GGDEF domain
APZ19_09765	COG0745	RESPONSE REGULATOR receiver
APZ19_09775	COG1451	nucleotide metabolic process
APZ19_09805	COG0583	DNA-binding transcription factor activity
APZ19_09835	COG4139	cobalamin transport
APZ19_09860	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
APZ19_09870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
APZ19_09875	COG0702	epimerase
APZ19_09890	COG2925	Exonuclease
APZ19_09900	COG1346	cytolysis
APZ19_09945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APZ19_09950	COG1621	beta-fructofuranosidase activity
APZ19_09960	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
APZ19_09960	COG0072	phenylalanine-tRNA ligase activity
APZ19_09970	COG2199	diguanylate cyclase activity
APZ19_10010	COG0251	oxidation-reduction process
APZ19_10030	COG0291	Belongs to the bacterial ribosomal protein bL35 family
APZ19_10055	COG2188	Transcriptional regulator
APZ19_10065	COG0010	Belongs to the arginase family
APZ19_10075	COG2986	histidine ammonia-lyase
APZ19_10090	COG0247	lactate metabolic process
APZ19_10090	COG0277	FAD linked oxidase domain protein
APZ19_10145	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
APZ19_10150	COG1643	Atp-dependent helicase
APZ19_10160	COG2949	membrane
APZ19_10165	COG0471	metal ion transport
APZ19_10170	COG3706	GGDEF domain
APZ19_10190	COG0492	ferredoxin-NADP+ reductase activity
APZ19_10195	COG4988	ABC transporter
APZ19_10200	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
APZ19_10210	COG0583	DNA-binding transcription factor activity
APZ19_10215	COG2200	EAL domain
APZ19_10255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
APZ19_10265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APZ19_10265	COG4191	Histidine kinase
APZ19_10280	COG3070	regulator of competence-specific genes
APZ19_10295	COG2431	L-lysine efflux transmembrane transporter activity
APZ19_10305	COG0076	glutamate decarboxylase activity
APZ19_10310	COG1737	Transcriptional regulator
APZ19_10320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
APZ19_10330	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
APZ19_10360	COG4181	ATPase activity
APZ19_10365	COG0534	Mate efflux family protein
APZ19_10370	COG0702	epimerase
APZ19_10375	COG4667	esterase of the alpha-beta hydrolase superfamily
APZ19_10385	COG2814	Major facilitator Superfamily
APZ19_10390	COG1187	pseudouridine synthase activity
APZ19_10395	COG1061	Type III restriction enzyme res subunit
APZ19_10400	COG2199	diguanylate cyclase activity
APZ19_10410	COG0745	RESPONSE REGULATOR receiver
APZ19_10415	COG2205	protein histidine kinase activity
APZ19_10455	COG3313	Fe-S protein
APZ19_10465	COG0659	secondary active sulfate transmembrane transporter activity
APZ19_10490	COG0493	'glutamate synthase
APZ19_10500	COG0398	Pfam SNARE associated Golgi protein
APZ19_10505	COG4134	Bacterial extracellular solute-binding protein
APZ19_10510	COG4135	transport system, permease component
APZ19_10515	COG4136	ATPase activity
APZ19_10520	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
APZ19_10525	COG3604	Transcriptional regulator
APZ19_10530	COG1151	hydroxylamine reductase activity
APZ19_10535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
APZ19_10550	COG0564	pseudouridine synthase activity
APZ19_10560	COG0733	neurotransmitter:sodium symporter activity
APZ19_10570	COG0626	cystathionine gamma-synthase activity
APZ19_10575	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
APZ19_10580	COG5380	lipid catabolic process
APZ19_10585	COG2818	Glycosylase
APZ19_10605	COG1983	PspC domain protein
APZ19_10615	COG1842	Phage shock protein A
APZ19_10620	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
APZ19_10630	COG4168	peptide transport system, permease
APZ19_10635	COG4171	peptide transport system, permease
APZ19_10645	COG4172	Belongs to the ABC transporter superfamily
APZ19_10655	COG1227	inorganic diphosphatase activity
APZ19_10670	COG0243	molybdopterin cofactor binding
APZ19_10675	COG3005	denitrification pathway
APZ19_10680	COG4459	periplasmic nitrate reductase
APZ19_10685	COG0390	transport system, permease component
APZ19_10690	COG2116	formate transmembrane transporter activity
APZ19_10715	COG1434	Gram-negative-bacterium-type cell wall biogenesis
APZ19_10720	COG1435	thymidine kinase activity
APZ19_10725	COG0215	cysteine-tRNA ligase activity
APZ19_10730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APZ19_10735	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
APZ19_10740	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
APZ19_10745	COG3012	SEC-C Motif Domain Protein
APZ19_10750	COG0140	phosphoribosyl-ATP diphosphatase activity
APZ19_10750	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
APZ19_10755	COG0107	imidazoleglycerol-phosphate synthase activity
APZ19_10760	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
APZ19_10765	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
APZ19_10770	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
APZ19_10770	COG0131	Imidazoleglycerol-phosphate dehydratase
APZ19_10780	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
APZ19_10790	COG1757	Na H antiporter
APZ19_10800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APZ19_10820	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
APZ19_10830	COG2268	Band 7 protein
APZ19_10840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
APZ19_10855	COG0300	oxidoreductase activity
APZ19_10895	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
APZ19_10900	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
APZ19_10915	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
APZ19_10925	COG1674	ftsk spoiiie
APZ19_10935	COG0686	Belongs to the AlaDH PNT family
APZ19_10945	COG0583	DNA-binding transcription factor activity
APZ19_10965	COG0800	Aldolase
APZ19_10970	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APZ19_10975	COG1917	Cupin 2, conserved barrel domain protein
APZ19_11005	COG0402	S-adenosylhomocysteine deaminase activity
APZ19_11015	COG3181	Tripartite tricarboxylate transporter family receptor
APZ19_11030	COG4934	collagen metabolic process
APZ19_11040	COG3568	Endonuclease Exonuclease Phosphatase
APZ19_11065	COG0701	Predicted permease
APZ19_11085	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_11090	COG1917	Cupin 2, conserved barrel domain protein
APZ19_11100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APZ19_11105	COG1904	glucuronate isomerase
APZ19_11130	COG2186	Transcriptional regulator
APZ19_11135	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_11140	COG2186	Transcriptional regulator
APZ19_11145	COG0517	IMP dehydrogenase activity
APZ19_11150	COG2176	DNA-directed DNA polymerase activity
APZ19_11160	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
APZ19_11175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
APZ19_11195	COG1120	ATPase activity
APZ19_11200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APZ19_11205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APZ19_11225	COG1288	antiporter activity
APZ19_11235	COG2186	Transcriptional regulator
APZ19_11245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APZ19_11250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APZ19_11275	COG0747	negative chemotaxis
APZ19_11280	COG4608	Belongs to the ABC transporter superfamily
APZ19_11285	COG0444	Belongs to the ABC transporter superfamily
APZ19_11290	COG0534	Mate efflux family protein
APZ19_11315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
APZ19_11320	COG2824	Alkylphosphonate utilization operon protein PhnA
APZ19_11325	COG2723	6-phospho-beta-galactosidase activity
APZ19_11330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APZ19_11330	COG1263	PTS System
APZ19_11345	COG3119	arylsulfatase activity
APZ19_11405	COG0514	ATP-dependent DNA helicase (RecQ)
APZ19_11410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
APZ19_11415	COG0302	gtp cyclohydrolase
APZ19_11420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
APZ19_11425	COG0602	queuosine metabolic process
APZ19_11470	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
APZ19_11500	COG0784	Response regulator, receiver
APZ19_11500	COG5002	protein histidine kinase activity
APZ19_11510	COG0754	glutathionylspermidine amidase activity
APZ19_11520	COG3766	membrane
APZ19_11535	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
APZ19_11540	COG2885	chlorophyll binding
APZ19_11545	COG0823	Involved in the tonB-independent uptake of proteins
APZ19_11560	COG0811	peptide transport
APZ19_11565	COG0824	Thioesterase
APZ19_11575	COG4890	Cyd operon protein YbgT
APZ19_11580	COG1294	oxidase, subunit
APZ19_11585	COG1271	oxidase subunit
APZ19_11595	COG0632	four-way junction helicase activity
APZ19_11600	COG0840	transmembrane signaling receptor activity
APZ19_11615	COG1801	Protein of unknown function DUF72
APZ19_11635	COG0189	ligase activity
APZ19_11635	COG4067	protein conserved in archaea
APZ19_11660	COG0318	PFAM AMP-dependent synthetase and ligase
APZ19_11675	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
APZ19_11680	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
APZ19_11690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
APZ19_11695	COG1434	Gram-negative-bacterium-type cell wall biogenesis
APZ19_11700	COG0745	RESPONSE REGULATOR receiver
APZ19_11720	COG3070	regulator of competence-specific genes
APZ19_11740	COG0297	glycogen (starch) synthase activity
APZ19_11745	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
APZ19_11750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APZ19_11780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
APZ19_11785	COG0542	response to heat
APZ19_11795	COG1278	Cold shock
APZ19_11805	COG1187	pseudouridine synthase activity
APZ19_11810	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
APZ19_11820	COG1199	ATP-dependent helicase activity
APZ19_11825	COG0730	response to heat
APZ19_11830	COG3923	Primosomal replication protein n
APZ19_11840	COG0840	transmembrane signaling receptor activity
APZ19_11845	COG0708	Exodeoxyribonuclease III
APZ19_11855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APZ19_11870	COG4215	(ABC) transporter
APZ19_11895	COG1882	Formate acetyltransferase
APZ19_11905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APZ19_11920	COG2766	serine protein kinase
APZ19_11925	COG2718	Belongs to the UPF0229 family
APZ19_11930	COG2719	SpoVR family
APZ19_11950	COG1132	(ABC) transporter
APZ19_11965	COG4591	ABC-type transport system involved in lipoprotein release permease component
APZ19_11970	COG1136	(ABC) transporter
APZ19_11975	COG4591	ABC-type transport system involved in lipoprotein release permease component
APZ19_11985	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
APZ19_12000	COG1252	NADH dehydrogenase
APZ19_12030	COG0537	adenosine 5'-monophosphoramidase activity
APZ19_12035	COG0840	transmembrane signaling receptor activity
APZ19_12060	COG0516	GMP reductase activity
APZ19_12060	COG0517	IMP dehydrogenase activity
APZ19_12065	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
APZ19_12070	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
APZ19_12075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APZ19_12080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
APZ19_12100	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
APZ19_12130	COG2199	diguanylate cyclase activity
APZ19_12145	COG3126	Type III secretion system lipoprotein chaperone (YscW)
APZ19_12150	COG1946	Acyl-CoA thioesterase
APZ19_12160	COG1522	sequence-specific DNA binding
APZ19_12180	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APZ19_12225	COG2855	membrane
APZ19_12235	COG0583	DNA-binding transcription factor activity
APZ19_12240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APZ19_12240	COG2190	(PTS) system
APZ19_12240	COG1263	PTS System
APZ19_12250	COG1441	menaquinone biosynthetic process
APZ19_12255	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
APZ19_12260	COG0596	Alpha beta hydrolase
APZ19_12270	COG1169	isochorismate synthase
APZ19_12275	COG0436	Aminotransferase
APZ19_12280	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
APZ19_12300	COG1555	photosystem II stabilization
APZ19_12305	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
APZ19_12310	COG0776	regulation of translation
APZ19_12315	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
APZ19_12345	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
APZ19_12350	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
APZ19_12355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
APZ19_12375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
APZ19_12380	COG0569	domain protein
APZ19_12385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
APZ19_12390	COG0513	Belongs to the DEAD box helicase family
APZ19_12395	COG1253	flavin adenine dinucleotide binding
APZ19_12400	COG4771	TonB-dependent receptor
APZ19_12415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
APZ19_12415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
APZ19_12420	COG3433	isochorismatase activity
APZ19_12420	COG1535	isochorismatase
APZ19_12425	COG1021	2,3-dihydroxybenzoate-AMP ligase
APZ19_12430	COG1169	isochorismate synthase
APZ19_12440	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_12485	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APZ19_12490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
APZ19_12510	COG1216	Glycosyl transferase, family 2
APZ19_12515	COG2986	histidine ammonia-lyase
APZ19_12550	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_12575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APZ19_12585	COG2951	lytic endotransglycosylase activity
APZ19_12600	COG2894	cell division
APZ19_12605	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
APZ19_12610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
APZ19_12615	COG0318	PFAM AMP-dependent synthetase and ligase
APZ19_12620	COG2267	carboxylic ester hydrolase activity
APZ19_12625	COG3065	identical protein binding
APZ19_12635	COG1214	PFAM Peptidase M22, glycoprotease
APZ19_12640	COG1199	ATP-dependent helicase activity
APZ19_12645	COG0788	formyltetrahydrofolate deformylase activity
APZ19_12650	COG3102	Protein conserved in bacteria
APZ19_12680	COG1918	ferrous iron import across plasma membrane
APZ19_12685	COG4977	sequence-specific DNA binding
APZ19_12690	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
APZ19_12695	COG1121	(ABC) transporter
APZ19_12700	COG1108	ABC-type Mn2 Zn2 transport systems permease components
APZ19_12715	COG0508	dehydrogenase complex catalyzes the overall conversion of
APZ19_12720	COG0567	Dehydrogenase, E1 component
APZ19_12730	COG1053	succinate dehydrogenase
APZ19_12735	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
APZ19_12740	COG2009	succinate dehydrogenase
APZ19_12750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
APZ19_12760	COG0033	Phosphoglucomutase
APZ19_12770	COG0596	Alpha beta hydrolase
APZ19_12780	COG0716	FMN binding
APZ19_12790	COG0735	belongs to the Fur family
APZ19_12805	COG1263	PTS System
APZ19_12805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APZ19_12805	COG2190	(PTS) system
APZ19_12815	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
APZ19_12820	COG1846	Transcriptional regulator
APZ19_12820	COG1940	carbohydrate kinase activity
APZ19_12825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
APZ19_12825	COG4651	solute:proton antiporter activity
APZ19_12830	COG0367	asparagine synthase
APZ19_12835	COG0250	Participates in transcription elongation, termination and antitermination
APZ19_12840	COG3104	oligopeptide transport
APZ19_12845	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
APZ19_12860	COG3710	Transcriptional regulator
APZ19_12880	COG0622	Phosphoesterase
APZ19_12910	COG1090	epimerase
APZ19_12915	COG0300	oxidoreductase activity
APZ19_12925	COG3118	belongs to the thioredoxin family
APZ19_12935	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
APZ19_12940	COG1215	transferase activity, transferring glycosyl groups
APZ19_12945	COG1215	transferase activity, transferring glycosyl groups
APZ19_12965	COG2194	sulfuric ester hydrolase activity
APZ19_12970	COG0330	HflC and HflK could
APZ19_13005	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
APZ19_13010	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
APZ19_13020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
APZ19_13025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APZ19_13030	COG2190	(PTS) system
APZ19_13035	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APZ19_13040	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APZ19_13045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APZ19_13060	COG1705	Flagellar rod assembly protein muramidase FlgJ
APZ19_13060	COG3951	Flagellar rod assembly protein muramidase FlgJ
APZ19_13065	COG1706	bacterial-type flagellum-dependent cell motility
APZ19_13070	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
APZ19_13075	COG4786	Flagellar basal body rod
APZ19_13080	COG4787	bacterial-type flagellum-dependent cell motility
APZ19_13085	COG1749	Flagellar hook protein flgE
APZ19_13090	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
APZ19_13095	COG1558	bacterial-type flagellum-dependent cell motility
APZ19_13100	COG1815	bacterial-type flagellum-dependent cell motility
APZ19_13105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
APZ19_13110	COG0835	chemotaxis
APZ19_13110	COG0784	Response regulator, receiver
APZ19_13165	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
APZ19_13180	COG2608	mercury ion transmembrane transporter activity
APZ19_13180	COG2217	Heavy metal translocating P-type atpase
APZ19_13215	COG2840	Smr protein MutS2
APZ19_13220	COG1187	pseudouridine synthase activity
APZ19_13225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
APZ19_13230	COG0737	Belongs to the 5'-nucleotidase family
APZ19_13240	COG2912	Transglutaminase-like superfamily
APZ19_13245	COG3094	Invasion gene expression up-regulator, SirB
APZ19_13250	COG2890	protein-(glutamine-N5) methyltransferase activity
APZ19_13275	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
APZ19_13395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
APZ19_13410	COG1702	phosphate starvation-inducible protein PhoH
APZ19_13420	COG4535	Mg2 and Co2 transporter CorC
APZ19_13425	COG0815	Transfers the fatty acyl group on membrane lipoproteins
APZ19_13430	COG2888	peptidyl-tyrosine sulfation
APZ19_13435	COG0495	leucyl-tRNA aminoacylation
APZ19_13440	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
APZ19_13445	COG1466	dna polymerase III delta subunit
APZ19_13450	COG0799	negative regulation of ribosome biogenesis
APZ19_13460	COG0768	penicillin binding
APZ19_13465	COG0772	Belongs to the SEDS family
APZ19_13470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
APZ19_13475	COG1686	Belongs to the peptidase S11 family
APZ19_13495	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APZ19_13500	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APZ19_13515	COG0366	Alpha amylase catalytic
APZ19_13520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APZ19_13520	COG1263	PTS System
APZ19_13530	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
APZ19_13535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
APZ19_13540	COG2011	ABC-type metal ion transport system permease component
APZ19_13545	COG1464	Belongs to the NlpA lipoprotein family
APZ19_13555	COG0737	Belongs to the 5'-nucleotidase family
APZ19_13560	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
APZ19_13580	COG3706	GGDEF domain
APZ19_13580	COG0745	RESPONSE REGULATOR receiver
APZ19_13585	COG1611	Belongs to the LOG family
APZ19_13600	COG2363	Small membrane protein
APZ19_13610	COG0583	DNA-binding transcription factor activity
APZ19_13625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
APZ19_13635	COG0142	geranyltranstransferase activity
APZ19_13645	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
APZ19_13650	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
APZ19_13675	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APZ19_13675	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
APZ19_13680	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
APZ19_13685	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
APZ19_13710	COG2252	PERMEase
APZ19_13715	COG2195	Cleaves the N-terminal amino acid of tripeptides
APZ19_13745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
APZ19_13745	COG0047	phosphoribosylformylglycinamidine synthase activity
APZ19_13765	COG0590	tRNA wobble adenosine to inosine editing
APZ19_13770	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
APZ19_13815	COG1301	dicarboxylic acid transport
APZ19_13835	COG0497	DNA recombination
APZ19_13840	COG0456	acetyltransferase
APZ19_13845	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APZ19_13855	COG2914	Belongs to the UPF0125 (RnfH) family
APZ19_13860	COG2867	negative regulation of translational initiation
APZ19_13875	COG0583	DNA-binding transcription factor activity
APZ19_13880	COG1289	transmembrane transporter activity
APZ19_13900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
APZ19_13905	COG2873	o-acetylhomoserine
APZ19_13910	COG0668	transmembrane transport
APZ19_13925	COG0583	DNA-binding transcription factor activity
APZ19_13935	COG1115	amino acid carrier protein
APZ19_13940	COG1584	GPR1 FUN34 yaaH family protein
APZ19_13950	COG1757	Na H antiporter
APZ19_13960	COG0517	IMP dehydrogenase activity
APZ19_13960	COG0516	GMP reductase activity
APZ19_13975	COG2203	Gaf domain
APZ19_13975	COG2199	diguanylate cyclase activity
APZ19_13990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APZ19_13995	COG2976	Protein conserved in bacteria
APZ19_14030	COG2975	iron-sulfur cluster assembly
APZ19_14035	COG0633	Ferredoxin
APZ19_14050	COG0316	Belongs to the HesB IscA family
APZ19_14055	COG0822	iron-sulfur transferase activity
APZ19_14070	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
APZ19_14075	COG0483	inositol monophosphate 1-phosphatase activity
APZ19_14080	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APZ19_14085	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APZ19_14090	COG1862	Preprotein translocase
APZ19_14115	COG0517	IMP dehydrogenase activity
APZ19_14125	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
APZ19_14130	COG0583	DNA-binding transcription factor activity
APZ19_14135	COG0450	alkyl hydroperoxide reductase
APZ19_14165	COG0704	Plays a role in the regulation of phosphate uptake
APZ19_14170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
APZ19_14175	COG0581	inorganic phosphate transmembrane transporter activity
APZ19_14180	COG0573	inorganic phosphate transmembrane transporter activity
APZ19_14185	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
APZ19_14190	COG0248	Ppx GppA phosphatase
APZ19_14200	COG5002	protein histidine kinase activity
APZ19_14205	COG0745	RESPONSE REGULATOR receiver
APZ19_14220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
APZ19_14280	COG0542	response to heat
APZ19_14290	COG0564	pseudouridine synthase activity
APZ19_14295	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APZ19_14300	COG0741	lytic transglycosylase activity
APZ19_14305	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
APZ19_14310	COG0077	Prephenate dehydratase
APZ19_14310	COG1605	Chorismate mutase
APZ19_14315	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
APZ19_14330	COG0488	(ABC) transporter
APZ19_14340	COG0739	heme binding
APZ19_14345	COG1605	Chorismate mutase
APZ19_14345	COG0287	Prephenate dehydrogenase
APZ19_14350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
APZ19_14355	COG1472	Belongs to the glycosyl hydrolase 3 family
APZ19_14360	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
APZ19_14380	COG1966	Carbon starvation protein
APZ19_14385	COG3275	phosphorelay sensor kinase activity
APZ19_14390	COG3279	Response regulator of the LytR AlgR family
APZ19_14395	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
APZ19_14400	COG1047	Peptidyl-prolyl cis-trans
APZ19_14415	COG0196	riboflavin kinase activity
APZ19_14420	COG0728	peptidoglycan biosynthetic process
APZ19_14425	COG0268	Binds directly to 16S ribosomal RNA
APZ19_14430	COG0640	Transcriptional regulator
APZ19_14435	COG0583	DNA-binding transcription factor activity
APZ19_14440	COG1283	sodium-dependent phosphate transmembrane transporter activity
APZ19_14455	COG0730	response to heat
APZ19_14480	COG0667	Aldo Keto reductase
APZ19_14505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
APZ19_14510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
APZ19_14520	COG0716	FMN binding
APZ19_14535	COG0513	Belongs to the DEAD box helicase family
APZ19_14545	COG3022	response to hydroperoxide
APZ19_14550	COG1115	amino acid carrier protein
APZ19_14590	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
APZ19_14595	COG0083	homoserine kinase activity
APZ19_14610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
APZ19_14625	COG0745	RESPONSE REGULATOR receiver
APZ19_14635	COG2198	Histidine kinase
APZ19_14635	COG0784	Response regulator, receiver
APZ19_14635	COG5002	protein histidine kinase activity
APZ19_14640	COG5001	Diguanylate cyclase
APZ19_14640	COG2203	Gaf domain
APZ19_14640	COG4251	negative regulation of phosphorylation
APZ19_14640	COG3706	GGDEF domain
APZ19_14645	COG1242	4 iron, 4 sulfur cluster binding
APZ19_14650	COG0069	glutamate synthase activity
APZ19_14650	COG0070	glutamate synthase
APZ19_14650	COG0067	glutamate synthase
APZ19_14660	COG0069	glutamate synthase activity
APZ19_14660	COG0067	glutamate synthase
APZ19_14660	COG0070	glutamate synthase
APZ19_14665	COG0493	'glutamate synthase
APZ19_14690	COG2860	membrane
APZ19_14695	COG0583	DNA-binding transcription factor activity
APZ19_14700	COG0730	response to heat
APZ19_14715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
APZ19_14720	COG0505	Belongs to the CarA family
APZ19_14730	COG0494	nUDIX hydrolase
APZ19_14750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
APZ19_14755	COG0849	cell division
APZ19_14760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
APZ19_14775	COG0772	Belongs to the SEDS family
APZ19_14790	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
APZ19_14795	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
APZ19_14800	COG0768	penicillin binding
APZ19_14805	COG3116	cell division
APZ19_14825	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
APZ19_14840	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
APZ19_14845	COG2823	Periplasmic or secreted lipoprotein
APZ19_14850	COG2969	positive regulation of protein catabolic process
APZ19_14855	COG0625	glutathione transferase activity
APZ19_14860	COG2857	Cytochrome c1
APZ19_14865	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
APZ19_14870	COG0723	plastoquinol--plastocyanin reductase activity
APZ19_14890	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
APZ19_14900	COG3105	Protein conserved in bacteria
APZ19_14905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APZ19_14910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
APZ19_14915	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
APZ19_14920	COG0187	DNA topoisomerase II activity
APZ19_14925	COG3150	esterase
APZ19_14935	COG3151	Protein conserved in bacteria
APZ19_14940	COG0494	nUDIX hydrolase
APZ19_14945	COG1538	Outer membrane efflux protein
APZ19_14955	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
APZ19_14965	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
APZ19_14970	COG3025	triphosphatase activity
APZ19_14975	COG1392	Phosphate transport regulator
APZ19_14980	COG0306	phosphate transporter
APZ19_14985	COG4991	sh3 domain protein
APZ19_14990	COG0405	Gamma-glutamyltransferase
APZ19_15000	COG3267	Type II secretory pathway component ExeA
APZ19_15000	COG3409	Peptidoglycan-binding domain 1 protein
APZ19_15015	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
APZ19_15020	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
APZ19_15030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
APZ19_15035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
APZ19_15040	COG0828	Belongs to the bacterial ribosomal protein bS21 family
APZ19_15045	COG1610	YqeY-like protein
APZ19_15050	COG0358	DNA primase activity
APZ19_15055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
APZ19_15085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
APZ19_15085	COG2213	PTS system mannitol-specific
APZ19_15095	COG3722	fumarate hydratase activity
APZ19_15100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
APZ19_15105	COG5002	protein histidine kinase activity
APZ19_15125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
APZ19_15130	COG1349	DNA-binding transcription factor activity
APZ19_15140	COG0469	pyruvate kinase activity
APZ19_15150	COG3706	GGDEF domain
APZ19_15160	COG0028	Belongs to the TPP enzyme family
APZ19_15165	COG1022	Amp-dependent synthetase and ligase
APZ19_15170	COG0583	DNA-binding transcription factor activity
APZ19_15200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
APZ19_15205	COG0473	3-isopropylmalate dehydrogenase activity
APZ19_15225	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
APZ19_15230	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
APZ19_15235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
APZ19_15240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
APZ19_15265	COG3610	response to peptide
APZ19_15270	COG2966	Psort location CytoplasmicMembrane, score
APZ19_15285	COG0261	This protein binds to 23S rRNA in the presence of protein L20
APZ19_15290	COG0142	geranyltranstransferase activity
APZ19_15330	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
APZ19_15335	COG1178	ABC-type Fe3 transport system permease component
APZ19_15340	COG4143	(ABC) transporter
APZ19_15345	COG0163	prenyltransferase activity
APZ19_15350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
APZ19_15360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
APZ19_15375	COG2105	PFAM AIG2 family protein
APZ19_15385	COG0729	surface antigen
APZ19_15390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APZ19_15465	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
APZ19_15495	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
APZ19_15510	COG1136	(ABC) transporter
APZ19_15530	COG0529	Catalyzes the synthesis of activated sulfate
APZ19_15535	COG0471	metal ion transport
APZ19_15535	COG3273	potassium ion transport
APZ19_15550	COG1648	precorrin-2 dehydrogenase activity
APZ19_15550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
APZ19_15555	COG0737	Belongs to the 5'-nucleotidase family
APZ19_15570	COG0513	Belongs to the DEAD box helicase family
APZ19_15575	COG2153	protein acetylation
APZ19_15590	COG0545	Peptidyl-prolyl cis-trans isomerase
APZ19_15600	COG0203	ribosomal protein L17
APZ19_15605	COG0202	RNA polymerase activity
APZ19_15615	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
APZ19_15620	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
APZ19_15630	COG0201	protein transport
APZ19_15640	COG1841	ribosomal large subunit assembly
APZ19_15670	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
APZ19_15705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
APZ19_15725	COG0088	Forms part of the polypeptide exit tunnel
APZ19_15740	COG0254	rRNA binding
APZ19_15750	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
APZ19_15755	COG1609	Transcriptional regulator
APZ19_15775	COG1575	Belongs to the MenA family. Type 1 subfamily
APZ19_15780	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
APZ19_15790	COG1494	fructose-1,6-bisphosphatase
APZ19_15820	COG0149	triose-phosphate isomerase activity
APZ19_15835	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
APZ19_15840	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
APZ19_15840	COG0517	IMP dehydrogenase activity
APZ19_15845	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
APZ19_15850	COG2877	3-deoxy-8-phosphooctulonate synthase activity
APZ19_15855	COG1215	transferase activity, transferring glycosyl groups
APZ19_15890	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_15965	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
APZ19_15975	COG1560	Kdo2-lipid A biosynthetic process
APZ19_15990	COG1519	Transferase
APZ19_16005	COG0367	asparagine synthase
APZ19_16030	COG1083	cytidylyl-transferase
APZ19_16035	COG3642	lipopolysaccharide core region biosynthetic process
APZ19_16040	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
APZ19_16045	COG0859	PFAM glycosyl transferase family 9
APZ19_16050	COG0463	Glycosyl transferase, family 2
APZ19_16065	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
APZ19_16100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
APZ19_16110	COG1560	Kdo2-lipid A biosynthetic process
APZ19_16120	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
APZ19_16125	COG1561	YicC-like family, N-terminal region
APZ19_16175	COG3645	SOS response
APZ19_16180	COG3645	SOS response
APZ19_16190	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
APZ19_16215	COG0745	RESPONSE REGULATOR receiver
APZ19_16240	COG4608	Belongs to the ABC transporter superfamily
APZ19_16245	COG0444	Belongs to the ABC transporter superfamily
APZ19_16250	COG0747	negative chemotaxis
APZ19_16255	COG4239	(ABC) transporter, permease
APZ19_16260	COG4174	ABC transporter (Permease)
APZ19_16285	COG0811	peptide transport
APZ19_16290	COG0848	biopolymer transport protein
APZ19_16305	COG0194	GDP metabolic process
APZ19_16310	COG1758	RNA polymerase activity
APZ19_16315	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
APZ19_16320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
APZ19_16325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
APZ19_16335	COG2233	PERMEase
APZ19_16340	COG2205	protein histidine kinase activity
APZ19_16345	COG0745	RESPONSE REGULATOR receiver
APZ19_16350	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
APZ19_16360	COG2183	response to ionizing radiation
APZ19_16385	COG0494	nUDIX hydrolase
APZ19_16390	COG1218	3'(2'),5'-bisphosphate nucleotidase
APZ19_16400	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
APZ19_16405	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
APZ19_16410	COG3156	type II secretion system protein K
APZ19_16415	COG4795	General secretion pathway protein
APZ19_16420	COG2165	general secretion pathway protein
APZ19_16425	COG2165	general secretion pathway protein
APZ19_16430	COG2165	general secretion pathway protein
APZ19_16435	COG1459	type II secretion system
APZ19_16440	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APZ19_16450	COG3031	protein transport across the cell outer membrane
APZ19_16455	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
APZ19_16475	COG0456	acetyltransferase
APZ19_16480	COG1490	D-aminoacyl-tRNA deacylase activity
APZ19_16505	COG0174	glutamine synthetase
APZ19_16515	COG3852	Histidine kinase
APZ19_16520	COG2204	response regulator
APZ19_16530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
APZ19_16535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
APZ19_16560	COG0218	Necessary for normal cell division and for the maintenance of normal septation
APZ19_16570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APZ19_16570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
APZ19_16590	COG0084	hydrolase, TatD family'
APZ19_16595	COG0805	protein transport
APZ19_16615	COG3165	ubiquinone biosynthetic process from chorismate
APZ19_16625	COG1322	Protein conserved in bacteria
APZ19_16660	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
APZ19_16730	COG2081	HI0933 family
APZ19_16765	COG1528	Iron-storage protein
APZ19_16770	COG0589	response to stress
APZ19_16775	COG0697	spore germination
APZ19_16790	COG5001	Diguanylate cyclase
APZ19_16790	COG5002	protein histidine kinase activity
APZ19_16795	COG1522	sequence-specific DNA binding
APZ19_16805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
APZ19_16815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
APZ19_16820	COG0800	Aldolase
APZ19_16825	COG2610	gluconate transmembrane transporter activity
APZ19_16830	COG3265	gluconokinase activity
APZ19_16835	COG0129	dihydroxy-acid dehydratase activity
APZ19_16845	COG2076	Multidrug Resistance protein
APZ19_16850	COG0583	DNA-binding transcription factor activity
APZ19_16855	COG1609	Transcriptional regulator
APZ19_16890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
APZ19_16905	COG4172	Belongs to the ABC transporter superfamily
APZ19_16950	COG1309	transcriptional regulator
APZ19_16955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APZ19_16960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APZ19_16970	COG2960	long-chain fatty acid transporting porin activity
APZ19_16975	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
APZ19_16980	COG0583	DNA-binding transcription factor activity
APZ19_17025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
APZ19_17050	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
APZ19_17055	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
APZ19_17060	COG0551	DNA topoisomerase type I activity
APZ19_17070	COG0758	DNA mediated transformation
APZ19_17080	COG0242	peptide deformylase activity
APZ19_17090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
APZ19_17090	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
APZ19_17095	COG0569	domain protein
APZ19_17100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
APZ19_17110	COG1272	protein, Hemolysin III
APZ19_17115	COG4326	sporulation control protein
APZ19_17125	COG3084	Protein conserved in bacteria
APZ19_17135	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
APZ19_17140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
APZ19_17145	COG0204	Acyl-transferase
APZ19_17155	COG0606	chelatase, subunit chli
APZ19_17165	COG3978	acetolactate synthase activity
APZ19_17170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
APZ19_17175	COG0129	dihydroxy-acid dehydratase activity
APZ19_17185	COG3706	GGDEF domain
APZ19_17190	COG0583	DNA-binding transcription factor activity
APZ19_17195	COG2814	Major facilitator Superfamily
APZ19_17200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APZ19_17205	COG0765	amino acid transport
APZ19_17215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
APZ19_17225	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APZ19_17255	COG3312	ion transport
APZ19_17260	COG1475	DNA binding
APZ19_17265	COG1192	Involved in chromosome partitioning
APZ19_17280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
APZ19_17295	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
APZ19_17310	COG1126	abc transporter atp-binding protein
APZ19_17390	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APZ19_17395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
APZ19_17405	COG1280	lysine exporter protein (LysE YggA)
APZ19_17415	COG0183	Belongs to the thiolase family
APZ19_17435	COG3005	denitrification pathway
APZ19_17455	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
APZ19_17460	COG3850	Histidine kinase
APZ19_17465	COG2197	response regulator
APZ19_17480	COG2195	Cleaves the N-terminal amino acid of tripeptides
APZ19_17500	COG0840	transmembrane signaling receptor activity
APZ19_17510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
APZ19_17540	COG0545	Peptidyl-prolyl cis-trans isomerase
APZ19_17570	COG1278	Cold shock
APZ19_17575	COG3036	rescue of stalled ribosome
APZ19_17585	COG3706	GGDEF domain
APZ19_17605	COG1136	(ABC) transporter
APZ19_17605	COG0577	efflux transmembrane transporter activity
APZ19_17635	COG1538	Outer membrane efflux protein
APZ19_17640	COG2205	protein histidine kinase activity
APZ19_17640	COG0784	Response regulator, receiver
APZ19_17670	COG0783	Belongs to the Dps family
APZ19_17680	COG1619	proteins homologs of microcin C7 resistance protein MccF
APZ19_17685	COG2133	pyrroloquinoline quinone binding
APZ19_17690	COG1454	alcohol dehydrogenase
APZ19_17695	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
APZ19_17715	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
APZ19_17720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
APZ19_17725	COG3186	Phenylalanine-4-hydroxylase
APZ19_17760	COG3530	Putative quorum-sensing-regulated virulence factor
APZ19_17790	COG0523	cobalamin synthesis protein
APZ19_17800	COG0513	Belongs to the DEAD box helicase family
APZ19_17820	COG2200	EAL domain
APZ19_17825	COG1119	ATPase activity
APZ19_17880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
APZ19_17895	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
APZ19_17900	COG0513	Belongs to the DEAD box helicase family
APZ19_17910	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
APZ19_17925	COG3278	Belongs to the heme-copper respiratory oxidase family
APZ19_17950	COG1024	Enoyl-CoA hydratase
APZ19_17955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
APZ19_17960	COG1960	acyl-CoA dehydrogenase activity
APZ19_17970	COG0183	Belongs to the thiolase family
APZ19_17985	COG1024	Enoyl-CoA hydratase
APZ19_17990	COG1024	Enoyl-CoA hydratase
APZ19_18000	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_18005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
APZ19_18010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
APZ19_18015	COG1845	cytochrome c oxidase, subunit III
APZ19_18020	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
APZ19_18030	COG0446	pyridine nucleotide-disulphide oxidoreductase
APZ19_18030	COG1902	pentaerythritol trinitrate reductase activity
APZ19_18045	COG1012	belongs to the aldehyde dehydrogenase family
APZ19_18055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
APZ19_18120	COG1126	abc transporter atp-binding protein
APZ19_18125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APZ19_18130	COG4215	(ABC) transporter
APZ19_18135	COG4160	amino acid transport
APZ19_18140	COG0840	transmembrane signaling receptor activity
APZ19_18160	COG3119	arylsulfatase activity
APZ19_18165	COG0431	NADPH-dependent FMN reductase
APZ19_18165	COG3976	FMN-binding domain protein
APZ19_18165	COG1053	succinate dehydrogenase
APZ19_18220	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
APZ19_18235	COG0443	Heat shock 70 kDa protein
APZ19_18240	COG2847	Copper chaperone PCu(A)C
APZ19_18270	COG0745	RESPONSE REGULATOR receiver
APZ19_18285	COG1785	Belongs to the alkaline phosphatase family
APZ19_18310	COG3706	GGDEF domain
APZ19_18320	COG0814	amino acid
APZ19_18325	COG5001	Diguanylate cyclase
APZ19_18325	COG5002	protein histidine kinase activity
APZ19_18335	COG0243	molybdopterin cofactor binding
APZ19_18365	COG1116	anion transmembrane transporter activity
APZ19_18365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
APZ19_18370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
APZ19_18375	COG1116	anion transmembrane transporter activity
APZ19_18380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
APZ19_18380	COG2146	nitrite reductase [NAD(P)H] activity
APZ19_18430	COG0745	RESPONSE REGULATOR receiver
APZ19_18435	COG2205	protein histidine kinase activity
APZ19_18435	COG2770	Histidine kinase
APZ19_18440	COG4968	Prepilin-type N-terminal cleavage methylation domain
APZ19_18460	COG1902	pentaerythritol trinitrate reductase activity
APZ19_18470	COG1475	DNA binding
APZ19_18525	COG2212	antiporter activity
APZ19_18530	COG1320	monovalent cation:proton antiporter activity
APZ19_18535	COG1294	oxidase, subunit
APZ19_18550	COG0583	DNA-binding transcription factor activity
APZ19_18560	COG0739	heme binding
APZ19_18595	COG0628	permease
APZ19_18635	COG1024	Enoyl-CoA hydratase
APZ19_18650	COG2207	Transcriptional regulator
APZ19_18650	COG0662	Cupin 2, conserved barrel domain protein
APZ19_18720	COG1132	(ABC) transporter
APZ19_18745	COG0583	DNA-binding transcription factor activity
APZ19_18750	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
APZ19_18765	COG2814	Major facilitator Superfamily
APZ19_18775	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_18790	COG1196	nuclear chromosome segregation
APZ19_18805	COG0509	glycine decarboxylation via glycine cleavage system
APZ19_18810	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
APZ19_18820	COG0404	The glycine cleavage system catalyzes the degradation of glycine
APZ19_18830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APZ19_18835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APZ19_18865	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APZ19_18865	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APZ19_18865	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
APZ19_18870	COG1105	Belongs to the carbohydrate kinase PfkB family
APZ19_18875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
APZ19_18875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
APZ19_18880	COG1609	Transcriptional regulator
APZ19_18895	COG2203	Gaf domain
APZ19_18895	COG2200	EAL domain
APZ19_18895	COG2199	diguanylate cyclase activity
APZ19_18900	COG0765	amino acid transport
APZ19_18905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
APZ19_18965	COG5532	Uncharacterized conserved protein (DUF2303)
APZ19_18990	COG1484	DNA-dependent DNA replication
APZ19_19250	COG0765	amino acid transport
APZ19_19255	COG1126	abc transporter atp-binding protein
APZ19_19265	COG1979	alcohol dehydrogenase
APZ19_19270	COG2207	Transcriptional regulator
APZ19_19280	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
APZ19_19290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APZ19_19305	COG3437	response regulator, receiver
APZ19_19305	COG0784	Response regulator, receiver
APZ19_19310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
APZ19_19315	COG0840	transmembrane signaling receptor activity
APZ19_19325	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
APZ19_19330	COG0513	Belongs to the DEAD box helicase family
APZ19_19335	COG4943	cyclic-guanylate-specific phosphodiesterase activity
APZ19_19350	COG3038	cytochrome b561
APZ19_19360	COG2116	formate transmembrane transporter activity
APZ19_19365	COG0583	DNA-binding transcription factor activity
APZ19_19375	COG3593	DNA synthesis involved in DNA repair
APZ19_19380	COG0737	Belongs to the 5'-nucleotidase family
APZ19_19400	COG0646	methionine synthase
APZ19_19400	COG1410	methionine synthase
APZ19_19415	COG2267	carboxylic ester hydrolase activity
APZ19_19435	COG2050	protein possibly involved in aromatic compounds catabolism
APZ19_19470	COG0484	heat shock protein binding
APZ19_19480	COG3300	MHYT domain
APZ19_19480	COG5001	Diguanylate cyclase
APZ19_19485	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
APZ19_19495	COG4181	ATPase activity
APZ19_19500	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
APZ19_19510	COG1984	allophanate hydrolase subunit 2
APZ19_19515	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
APZ19_19525	COG5002	protein histidine kinase activity
APZ19_19525	COG5001	Diguanylate cyclase
APZ19_19525	COG3447	MASE1 domain protein
APZ19_19530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
APZ19_19545	COG0583	DNA-binding transcription factor activity
APZ19_19550	COG0045	succinate-CoA ligase (ADP-forming) activity
APZ19_19550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APZ19_19550	COG1042	CoA-binding domain protein
APZ19_19570	COG0023	Translation Initiation Factor
APZ19_19590	COG3140	Belongs to the UPF0181 family
APZ19_19615	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
APZ19_19620	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
APZ19_19645	COG0745	RESPONSE REGULATOR receiver
APZ19_19645	COG3706	GGDEF domain
APZ19_19660	COG4251	negative regulation of phosphorylation
APZ19_19660	COG5001	Diguanylate cyclase
APZ19_19660	COG2203	Gaf domain
APZ19_19660	COG3706	GGDEF domain
APZ19_19670	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
APZ19_19675	COG4149	molybdate abc transporter
APZ19_19680	COG0725	ABC transporter, periplasmic molybdate-binding protein
APZ19_19690	COG3111	PFAM Bacterial OB fold (BOF) protein
APZ19_19715	COG0534	Mate efflux family protein
APZ19_19720	COG0602	queuosine metabolic process
APZ19_19725	COG1328	CTP reductase activity
APZ19_19800	COG2197	response regulator
APZ19_19805	COG3851	Histidine kinase
APZ19_19810	COG2271	Major facilitator Superfamily
APZ19_19815	COG1482	cell wall glycoprotein biosynthetic process
APZ19_19825	COG0628	permease
APZ19_19835	COG1566	PFAM secretion protein HlyD family protein
APZ19_19865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
APZ19_19870	COG3118	belongs to the thioredoxin family
APZ19_19875	COG2814	Major facilitator Superfamily
APZ19_19885	COG0534	Mate efflux family protein
APZ19_19905	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
APZ19_19925	COG2116	formate transmembrane transporter activity
APZ19_19930	COG2146	nitrite reductase [NAD(P)H] activity
APZ19_19935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
APZ19_19945	COG2199	diguanylate cyclase activity
APZ19_20020	COG0277	FAD linked oxidase domain protein
APZ19_20025	COG0583	DNA-binding transcription factor activity
APZ19_20030	COG1472	Belongs to the glycosyl hydrolase 3 family
APZ19_20040	COG2425	protein containing a von Willebrand factor type A (vWA) domain
APZ19_20055	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
APZ19_20065	COG1288	antiporter activity
APZ19_20075	COG2814	Major facilitator Superfamily
APZ19_20085	COG3040	lipid binding
APZ19_20115	COG3469	chitinase activity
APZ19_20125	COG0419	ATPase involved in DNA repair
APZ19_20130	COG0420	3'-5' exonuclease activity
APZ19_20155	COG3501	Rhs element vgr protein
APZ19_20210	COG0631	protein serine/threonine phosphatase activity
APZ19_20245	COG2815	serine threonine protein kinase
APZ19_20245	COG0515	serine threonine protein kinase
APZ19_20285	COG0346	lactoylglutathione lyase activity
APZ19_20290	COG1902	pentaerythritol trinitrate reductase activity
APZ19_20300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
APZ19_20300	COG2755	lipolytic protein G-D-S-L family
APZ19_20315	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
APZ19_20315	COG0069	glutamate synthase activity
APZ19_20325	COG1234	tRNA 3'-trailer cleavage
APZ19_20330	COG2067	long-chain fatty acid transport protein
APZ19_20365	COG2076	Multidrug Resistance protein
APZ19_20375	COG0671	phosphoesterase, PA-phosphatase related
APZ19_20390	COG2962	Rard protein
APZ19_20405	COG0784	Response regulator, receiver
APZ19_20405	COG0835	chemotaxis
APZ19_20410	COG0778	Nitroreductase
APZ19_20420	COG2197	response regulator
APZ19_20430	COG3706	GGDEF domain
APZ19_20435	COG2197	response regulator
APZ19_20440	COG3300	MHYT domain
APZ19_20440	COG5001	Diguanylate cyclase
APZ19_20445	COG2205	protein histidine kinase activity
APZ19_20445	COG0784	Response regulator, receiver
APZ19_20460	COG4771	TonB-dependent receptor
APZ19_20515	COG1522	sequence-specific DNA binding
APZ19_20550	COG0515	serine threonine protein kinase
APZ19_20575	COG3501	Rhs element vgr protein
APZ19_20590	COG2204	response regulator
APZ19_20595	COG2885	chlorophyll binding
APZ19_20630	COG0739	heme binding
APZ19_20635	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
APZ19_20665	COG3069	C4-dicarboxylate transmembrane transporter activity
APZ19_20670	COG1704	LemA family
APZ19_20675	COG0501	Belongs to the peptidase M48B family
APZ19_20705	COG0641	radical SAM
APZ19_20725	COG3111	PFAM Bacterial OB fold (BOF) protein
APZ19_20730	COG1597	lipid kinase activity
APZ19_20745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
APZ19_20755	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
APZ19_20815	COG0714	Associated with various cellular activities
APZ19_20820	COG0641	radical SAM
APZ19_20825	COG3119	arylsulfatase activity
APZ19_20830	COG0583	DNA-binding transcription factor activity
APZ19_20840	COG3119	arylsulfatase activity
APZ19_20845	COG3119	arylsulfatase activity
APZ19_20850	COG3119	arylsulfatase activity
APZ19_20880	COG2205	protein histidine kinase activity
APZ19_20880	COG0784	Response regulator, receiver
APZ19_20880	COG2198	Histidine kinase
APZ19_20885	COG1879	ABC-type sugar transport system periplasmic component
APZ19_20895	COG0210	DNA helicase
APZ19_20900	COG1289	transmembrane transporter activity
APZ19_20930	COG4206	TonB-dependent receptor
APZ19_20940	COG0789	Transcriptional regulator
APZ19_20945	COG4604	ABC transporter, ATP-binding protein
APZ19_20950	COG4605	iron ion homeostasis
APZ19_20955	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APZ19_20960	COG4607	ABC-type enterochelin transport system periplasmic component
APZ19_20975	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
APZ19_20990	COG1609	Transcriptional regulator
APZ19_20995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APZ19_21000	COG1879	ABC-type sugar transport system periplasmic component
APZ19_21005	COG1172	Belongs to the binding-protein-dependent transport system permease family
APZ19_21010	COG1129	ABC transporter
APZ19_21020	COG5001	Diguanylate cyclase
APZ19_21025	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APZ19_21030	COG1794	racemase activity, acting on amino acids and derivatives
APZ19_21035	COG1051	belongs to the nudix hydrolase family
APZ19_21060	COG0586	Pfam SNARE associated Golgi protein
APZ19_21080	COG0745	RESPONSE REGULATOR receiver
APZ19_21125	COG0583	DNA-binding transcription factor activity
APZ19_21135	COG0784	Response regulator, receiver
APZ19_21135	COG2205	protein histidine kinase activity
APZ19_21145	COG2205	protein histidine kinase activity
APZ19_21145	COG0784	Response regulator, receiver
APZ19_21150	COG2199	diguanylate cyclase activity
APZ19_21150	COG2200	EAL domain
APZ19_21150	COG2203	Gaf domain
APZ19_21180	COG0330	HflC and HflK could
APZ19_21245	COG0529	Catalyzes the synthesis of activated sulfate
APZ19_21250	COG3273	potassium ion transport
APZ19_21250	COG0471	metal ion transport
APZ19_21260	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
APZ19_21275	COG0438	transferase activity, transferring glycosyl groups
APZ19_21295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
APZ19_21300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
APZ19_21305	COG2895	sulfate adenylyltransferase (ATP) activity
APZ19_21310	COG0175	sulfate reduction
APZ19_21320	COG1596	polysaccharide export
APZ19_21325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
APZ19_21330	COG4175	Glycine betaine
APZ19_21330	COG0517	IMP dehydrogenase activity
APZ19_21335	COG4176	ABC-type proline glycine betaine transport system permease component
APZ19_21370	COG3706	GGDEF domain
APZ19_21415	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
APZ19_21415	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
APZ19_21430	COG4989	oxidoreductase activity
APZ19_21455	COG1914	H( )-stimulated, divalent metal cation uptake system
APZ19_21490	COG2897	thiosulfate sulfurtransferase activity
APZ19_21515	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
APZ19_21520	COG0840	transmembrane signaling receptor activity
APZ19_21525	COG2814	Major facilitator Superfamily
APZ19_21530	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
APZ19_21545	COG1612	heme a metabolic process
APZ19_21565	COG1845	cytochrome c oxidase, subunit III
APZ19_21570	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
APZ19_21585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
APZ19_21595	COG1280	lysine exporter protein (LysE YggA)
APZ19_21615	COG0179	Fumarylacetoacetate (FAA) hydrolase
APZ19_21630	COG0697	spore germination
APZ19_21650	COG2814	Major facilitator Superfamily
APZ19_21655	COG0583	DNA-binding transcription factor activity
APZ19_21670	COG4774	siderophore transport
APZ19_21685	COG1120	ATPase activity
APZ19_21690	COG5001	Diguanylate cyclase
APZ19_21695	COG0739	heme binding
APZ19_21735	COG0814	amino acid
APZ19_21750	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
APZ19_21755	COG1072	(Pantothenic acid kinase))
APZ19_21765	COG1063	alcohol dehydrogenase
APZ19_21770	COG2213	PTS system mannitol-specific
APZ19_21775	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APZ19_21780	COG2188	Transcriptional regulator
APZ19_21785	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APZ19_21785	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APZ19_21785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APZ19_21790	COG0383	alpha-mannosidase activity
APZ19_21795	COG1482	cell wall glycoprotein biosynthetic process
APZ19_21805	COG4989	oxidoreductase activity
APZ19_21825	COG1733	regulation of RNA biosynthetic process
APZ19_21840	COG0798	PFAM Bile acid sodium symporter
APZ19_21855	COG1881	PFAM PEBP family protein
APZ19_21865	COG0251	oxidation-reduction process
APZ19_21870	COG2706	6-phosphogluconolactonase activity
APZ19_21880	COG0800	Aldolase
APZ19_21885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APZ19_21890	COG4145	pantothenate transmembrane transporter activity
APZ19_21900	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
APZ19_21925	COG1131	(ABC) transporter
APZ19_21930	COG0842	Transport permease protein
APZ19_21945	COG3383	formate dehydrogenase (NAD+) activity
APZ19_21965	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APZ19_22010	COG0494	nUDIX hydrolase
APZ19_22025	COG1858	cytochrome C peroxidase
APZ19_22035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APZ19_22045	COG2067	long-chain fatty acid transport protein
APZ19_22055	COG1505	serine-type exopeptidase activity
APZ19_22060	COG0488	(ABC) transporter
APZ19_22065	COG1720	tRNA m6t6A37 methyltransferase activity
APZ19_22085	COG0589	response to stress
APZ19_22110	COG1175	transmembrane transport
APZ19_22115	COG0395	ABC-type sugar transport system, permease component
APZ19_22120	COG3842	ATPase activity
APZ19_22140	COG1846	Transcriptional regulator
APZ19_22160	COG0523	cobalamin synthesis protein
APZ19_22170	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
APZ19_22180	COG4667	esterase of the alpha-beta hydrolase superfamily
APZ19_22185	COG1741	Belongs to the pirin family
APZ19_22190	COG1278	Cold shock
APZ19_22205	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
APZ19_22210	COG3706	GGDEF domain
APZ19_22235	COG2226	methyltransferase
APZ19_22245	COG3706	GGDEF domain
APZ19_22250	COG1686	Belongs to the peptidase S11 family
APZ19_22255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
APZ19_22260	COG2249	NAD(P)H dehydrogenase (quinone) activity
APZ19_22270	COG0625	glutathione transferase activity
APZ19_22280	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
APZ19_22290	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_22315	COG3746	phosphate-selective porin O and P
APZ19_22330	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_22340	COG0583	DNA-binding transcription factor activity
APZ19_22345	COG2207	Transcriptional regulator
APZ19_22345	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
APZ19_22350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
APZ19_22380	COG0513	Belongs to the DEAD box helicase family
APZ19_22390	COG0583	DNA-binding transcription factor activity
APZ19_22410	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_22415	COG2814	Major facilitator Superfamily
APZ19_22425	COG1902	pentaerythritol trinitrate reductase activity
APZ19_22440	COG3122	Protein conserved in bacteria
APZ19_22445	COG0583	DNA-binding transcription factor activity
APZ19_22465	COG0583	DNA-binding transcription factor activity
APZ19_22485	COG0252	asparaginase activity
APZ19_22495	COG0574	Belongs to the PEP-utilizing enzyme family
APZ19_22495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
APZ19_22505	COG2197	response regulator
APZ19_22510	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
APZ19_22560	COG0583	DNA-binding transcription factor activity
APZ19_22565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APZ19_22580	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
APZ19_22585	COG0786	glutamate:sodium symporter activity
APZ19_22615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
APZ19_22620	COG0318	PFAM AMP-dependent synthetase and ligase
APZ19_22640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APZ19_22650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
APZ19_22660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
APZ19_22705	COG1621	beta-fructofuranosidase activity
APZ19_22710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APZ19_22710	COG1263	PTS System
APZ19_22715	COG2188	Transcriptional regulator
APZ19_22730	COG4948	Mandelate Racemase Muconate Lactonizing
APZ19_22735	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
APZ19_22770	COG1342	Belongs to the UPF0251 family
APZ19_22780	COG4176	ABC-type proline glycine betaine transport system permease component
APZ19_22785	COG4175	Glycine betaine
APZ19_22785	COG3448	diguanylate cyclase activity
APZ19_22800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
APZ19_22805	COG0583	DNA-binding transcription factor activity
APZ19_22855	COG1335	isochorismatase
APZ19_22870	COG0753	catalase activity
APZ19_22890	COG1482	cell wall glycoprotein biosynthetic process
APZ19_22895	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
APZ19_22900	COG1263	PTS System
APZ19_22900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APZ19_22905	COG1609	Transcriptional regulator
APZ19_22910	COG1349	DNA-binding transcription factor activity
APZ19_22915	COG0346	lactoylglutathione lyase activity
APZ19_22920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APZ19_22920	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APZ19_22930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APZ19_22935	COG3537	Alpha-1,2-mannosidase
APZ19_22940	COG3537	Alpha-1,2-mannosidase
APZ19_22950	COG3537	Alpha-1,2-mannosidase
APZ19_22955	COG3537	Alpha-1,2-mannosidase
APZ19_22960	COG0737	Belongs to the 5'-nucleotidase family
APZ19_22990	COG1280	lysine exporter protein (LysE YggA)
APZ19_22995	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
APZ19_23010	COG3226	Transcriptional regulator
APZ19_23025	COG0583	DNA-binding transcription factor activity
APZ19_23055	COG0431	NADPH-dependent FMN reductase
APZ19_23060	COG0583	DNA-binding transcription factor activity
APZ19_23065	COG4628	conserved protein (DUF2132)
APZ19_23070	COG0488	(ABC) transporter
APZ19_23085	COG0346	lactoylglutathione lyase activity
APZ19_23090	COG0384	phenazine biosynthesis protein PhzF
APZ19_23105	COG3220	belongs to the UPF0276 family
APZ19_23120	COG1271	oxidase subunit
APZ19_23125	COG1294	oxidase, subunit
APZ19_23170	COG2207	Transcriptional regulator
APZ19_23185	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
APZ19_23190	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
APZ19_23205	COG2205	protein histidine kinase activity
APZ19_23210	COG0745	RESPONSE REGULATOR receiver
APZ19_23220	COG0454	-acetyltransferase
APZ19_23225	COG0148	phosphopyruvate hydratase activity
APZ19_23235	COG2814	Major facilitator Superfamily
APZ19_23250	COG2988	succinylglutamate desuccinylase activity
APZ19_23290	COG0628	permease
APZ19_23295	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
APZ19_23310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
APZ19_23320	COG4628	conserved protein (DUF2132)
APZ19_23325	COG0583	DNA-binding transcription factor activity
APZ19_23350	COG1686	Belongs to the peptidase S11 family
APZ19_23370	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APZ19_23375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
APZ19_23400	COG0415	Belongs to the DNA photolyase family
APZ19_23405	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
APZ19_23415	COG4667	esterase of the alpha-beta hydrolase superfamily
APZ19_23420	COG2095	MarC family integral membrane protein
APZ19_23455	COG0583	DNA-binding transcription factor activity
APZ19_23460	COG2814	Major facilitator Superfamily
APZ19_23490	COG1301	dicarboxylic acid transport
APZ19_23495	COG3339	Conserved Protein
APZ19_23500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
APZ19_23505	COG0700	Nucleoside recognition
APZ19_23510	COG3366	ferrous iron transmembrane transporter activity
APZ19_23525	COG0366	Alpha amylase catalytic
APZ19_23535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
APZ19_23540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
APZ19_23545	COG1640	4-alpha-glucanotransferase
APZ19_23550	COG0058	SHG alpha-glucan phosphorylase activity
APZ19_23585	COG1162	GTPase activity
APZ19_23590	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
APZ19_23595	COG0673	inositol 2-dehydrogenase activity
APZ19_23620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APZ19_23625	COG0673	inositol 2-dehydrogenase activity
APZ19_23630	COG3962	Belongs to the TPP enzyme family
APZ19_23640	COG2814	Major facilitator Superfamily
APZ19_23640	COG0477	Major facilitator Superfamily
APZ19_23660	COG0183	Belongs to the thiolase family
APZ19_23665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
APZ19_23690	COG0531	amino acid
APZ19_23695	COG1982	Orn Lys Arg decarboxylase major
APZ19_23715	COG2356	endonuclease I
APZ19_23745	COG2199	diguanylate cyclase activity
APZ19_23745	COG2203	Gaf domain
APZ19_23765	COG2221	Nitrite and sulphite reductase 4Fe-4S
APZ19_23770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
APZ19_23785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APZ19_23785	COG1263	PTS System
APZ19_23790	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_23795	COG1760	l-serine dehydratase
APZ19_23820	COG1609	Transcriptional regulator
APZ19_23830	COG2814	Major facilitator Superfamily
APZ19_23835	COG3214	Protein conserved in bacteria
APZ19_23845	COG4771	TonB-dependent receptor
APZ19_23850	COG0583	DNA-binding transcription factor activity
APZ19_23855	COG4607	ABC-type enterochelin transport system periplasmic component
APZ19_23860	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APZ19_23865	COG4605	iron ion homeostasis
APZ19_23870	COG4604	ABC transporter, ATP-binding protein
APZ19_23895	COG0739	heme binding
APZ19_23910	COG0800	Aldolase
APZ19_23915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APZ19_23920	COG2190	(PTS) system
APZ19_23920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APZ19_23920	COG1263	PTS System
APZ19_23930	COG2188	Transcriptional regulator
APZ19_23940	COG1621	beta-fructofuranosidase activity
APZ19_23955	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
APZ19_23960	COG1554	hydrolase, family 65, central catalytic
APZ19_23965	COG0395	ABC-type sugar transport system, permease component
APZ19_24000	COG3121	Chaperone
APZ19_24005	COG3188	usher protein
APZ19_24035	COG0612	Peptidase, M16
APZ19_24040	COG0840	transmembrane signaling receptor activity
APZ19_24070	COG0667	Aldo Keto reductase
APZ19_24080	COG2249	NAD(P)H dehydrogenase (quinone) activity
APZ19_24085	COG0666	response to abiotic stimulus
APZ19_24090	COG0583	DNA-binding transcription factor activity
APZ19_24100	COG1136	(ABC) transporter
APZ19_24150	COG1764	response to oxidative stress
APZ19_24155	COG1846	Transcriptional regulator
APZ19_24160	COG0450	alkyl hydroperoxide reductase
APZ19_24165	COG3634	alkyl hydroperoxide reductase activity
APZ19_24185	COG2188	Transcriptional regulator
APZ19_24190	COG2271	Major facilitator Superfamily
APZ19_24195	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APZ19_24200	COG1397	ADP-ribosylglycohydrolase
APZ19_24205	COG2211	Major facilitator Superfamily
APZ19_24225	COG0346	lactoylglutathione lyase activity
APZ19_24230	COG0840	transmembrane signaling receptor activity
APZ19_24240	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
APZ19_24250	COG1522	sequence-specific DNA binding
APZ19_24265	COG2258	MOSC domain
APZ19_24270	COG1609	Transcriptional regulator
APZ19_24275	COG1757	Na H antiporter
APZ19_24280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
APZ19_24285	COG0513	Belongs to the DEAD box helicase family
APZ19_24305	COG1595	DNA-templated transcription, initiation
APZ19_24315	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
APZ19_24320	COG1312	Catalyzes the dehydration of D-mannonate
APZ19_24325	COG2186	Transcriptional regulator
APZ19_24335	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
APZ19_24345	COG0246	Mannitol dehydrogenase
APZ19_24350	COG1904	glucuronate isomerase
APZ19_24355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
APZ19_24360	COG0800	Aldolase
APZ19_24375	COG0549	Belongs to the carbamate kinase family
APZ19_24380	COG0531	amino acid
APZ19_24385	COG2957	Belongs to the agmatine deiminase family
APZ19_24410	COG1132	(ABC) transporter
APZ19_24435	COG0406	alpha-ribazole phosphatase activity
APZ19_24530	COG4166	transmembrane transport
APZ19_24545	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
APZ19_24550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
APZ19_24550	COG1263	PTS System
APZ19_24555	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
APZ19_24580	COG1444	tRNA N-acetyltransferase activity
APZ19_24605	COG4608	Belongs to the ABC transporter superfamily
APZ19_24610	COG0444	Belongs to the ABC transporter superfamily
APZ19_24620	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
APZ19_24620	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
APZ19_24645	COG0772	Belongs to the SEDS family
APZ19_24655	COG1566	PFAM secretion protein HlyD family protein
APZ19_24660	COG0583	DNA-binding transcription factor activity
APZ19_24670	COG1136	(ABC) transporter
APZ19_24690	COG3275	phosphorelay sensor kinase activity
APZ19_24695	COG3279	Response regulator of the LytR AlgR family
APZ19_24705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
APZ19_24730	COG0786	glutamate:sodium symporter activity
APZ19_24745	COG1131	(ABC) transporter
APZ19_24750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
APZ19_24755	COG0786	glutamate:sodium symporter activity
APZ19_24775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
APZ19_24820	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
APZ19_24830	COG2207	Transcriptional regulator
APZ19_24835	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
APZ19_24845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APZ19_24855	COG0251	oxidation-reduction process
APZ19_24860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
APZ19_24905	COG0561	phosphatase activity
APZ19_24910	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
APZ19_24915	COG3623	hexulose-6-phosphate isomerase
APZ19_24955	COG1741	Belongs to the pirin family
APZ19_24960	COG2259	Doxx family
APZ19_24970	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
APZ19_24975	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
APZ19_24985	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
APZ19_25105	COG5001	Diguanylate cyclase
APZ19_25110	COG4580	involved in the transport of maltose and maltodextrins
APZ19_25115	COG1609	Transcriptional regulator
APZ19_25130	COG0395	ABC-type sugar transport system, permease component
APZ19_25135	COG2723	6-phospho-beta-galactosidase activity
APZ19_25140	COG3842	ATPase activity
APZ19_25145	COG1609	Transcriptional regulator
APZ19_25150	COG0534	Mate efflux family protein
APZ19_25155	COG0564	pseudouridine synthase activity
APZ19_25170	COG0561	phosphatase activity
APZ19_25180	COG2199	diguanylate cyclase activity
APZ19_25190	COG3152	Membrane
APZ19_25205	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
APZ19_25210	COG2162	N-hydroxyarylamine O-acetyltransferase activity
APZ19_25225	COG0583	DNA-binding transcription factor activity
APZ19_25270	COG2076	Multidrug Resistance protein
APZ19_25285	COG1357	PFAM Pentapeptide repeats (8 copies)
APZ19_25290	COG3047	cAMP biosynthetic process
APZ19_25310	COG2814	Major facilitator Superfamily
APZ19_25330	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
APZ19_25330	COG3408	Glycogen debranching enzyme
APZ19_25360	COG0583	DNA-binding transcription factor activity
APZ19_25400	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APZ19_25435	COG1228	amidohydrolase
APZ19_25445	COG3835	regulator
APZ19_25450	COG1929	Belongs to the glycerate kinase type-1 family
APZ19_25455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
APZ19_25500	COG0456	acetyltransferase
APZ19_25520	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_25530	COG3005	denitrification pathway
APZ19_25535	COG0243	molybdopterin cofactor binding
APZ19_25540	COG5002	protein histidine kinase activity
APZ19_25550	COG0671	phosphoesterase, PA-phosphatase related
APZ19_25575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
APZ19_25580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
APZ19_25585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
APZ19_25590	COG1116	anion transmembrane transporter activity
APZ19_25595	COG0351	phosphomethylpyrimidine kinase
APZ19_25600	COG0312	modulator of DNA gyrase
APZ19_25605	COG0312	modulator of DNA gyrase
APZ19_25670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
APZ19_25680	COG0584	glycerophosphoryl diester phosphodiesterase
APZ19_25690	COG0745	RESPONSE REGULATOR receiver
APZ19_25710	COG0811	peptide transport
APZ19_25715	COG0811	peptide transport
APZ19_25720	COG0848	biopolymer transport protein
APZ19_25765	COG0803	Belongs to the bacterial solute-binding protein 9 family
APZ19_25770	COG1121	(ABC) transporter
APZ19_25775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
APZ19_25790	COG1770	oligopeptidase
APZ19_25795	COG2814	Major facilitator Superfamily
APZ19_25800	COG0010	Belongs to the arginase family
APZ19_25805	COG1166	arginine decarboxylase activity
APZ19_25815	COG4067	protein conserved in archaea
APZ19_25815	COG0189	ligase activity
APZ19_25820	COG0189	ligase activity
APZ19_25840	COG0583	DNA-binding transcription factor activity
APZ19_25880	COG3706	GGDEF domain
APZ19_25905	COG0579	oxidoreductase
APZ19_25925	COG3033	Beta-eliminating lyase
APZ19_25940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
APZ19_25945	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
APZ19_25965	COG3706	GGDEF domain
APZ19_25980	COG3706	GGDEF domain
APZ19_25985	COG0415	Belongs to the DNA photolyase family
APZ19_25990	COG3046	protein related to deoxyribodipyrimidine photolyase
APZ19_26005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APZ19_26005	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
APZ19_26010	COG1765	OsmC-like protein
APZ19_26015	COG2171	N-acyltransferase activity
APZ19_26050	COG1011	Hydrolase
APZ19_26085	COG3240	lipase activity
APZ19_26115	COG1609	Transcriptional regulator
APZ19_26135	COG1840	ABC-type Fe3 transport system, periplasmic component
APZ19_26140	COG3842	ATPase activity
APZ19_26165	COG2990	Protein conserved in bacteria
APZ19_26175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
APZ19_26180	COG2866	Carboxypeptidase
APZ19_26190	COG0583	DNA-binding transcription factor activity
APZ19_26220	COG1760	l-serine dehydratase
APZ19_26245	COG1388	LysM domain
APZ19_26245	COG0741	lytic transglycosylase activity
APZ19_26265	COG1815	bacterial-type flagellum-dependent cell motility
APZ19_26270	COG1558	bacterial-type flagellum-dependent cell motility
APZ19_26275	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
APZ19_26280	COG1749	Flagellar hook protein flgE
APZ19_26285	COG4787	bacterial-type flagellum-dependent cell motility
APZ19_26290	COG4786	Flagellar basal body rod
APZ19_26295	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
APZ19_26300	COG1706	bacterial-type flagellum-dependent cell motility
APZ19_26310	COG1256	bacterial-type flagellum assembly
APZ19_26310	COG4786	Flagellar basal body rod
APZ19_26315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APZ19_26340	COG0583	DNA-binding transcription factor activity
APZ19_26360	COG1253	flavin adenine dinucleotide binding
APZ19_26365	COG3710	Transcriptional regulator
APZ19_26380	COG2226	methyltransferase
APZ19_26435	COG1360	Flagellar Motor Protein
APZ19_26440	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
APZ19_26445	COG1191	sigma factor activity
APZ19_26450	COG1580	Controls the rotational direction of flagella during chemotaxis
APZ19_26465	COG1516	flagellar protein fliS
APZ19_26470	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
APZ19_26480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
APZ19_26495	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
APZ19_26505	COG1987	bacterial-type flagellum assembly
APZ19_26530	COG2204	response regulator
APZ19_26545	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
APZ19_26565	COG5002	protein histidine kinase activity
APZ19_26565	COG5001	Diguanylate cyclase
APZ19_26580	COG0697	spore germination
APZ19_26625	COG0346	lactoylglutathione lyase activity
APZ19_26650	COG0745	RESPONSE REGULATOR receiver
APZ19_26675	COG0156	8-amino-7-oxononanoate synthase activity
APZ19_26680	COG1063	alcohol dehydrogenase
APZ19_26740	COG0668	transmembrane transport
APZ19_26755	COG1304	FMN binding
APZ19_26760	COG1620	l-lactate permease
APZ19_26765	COG0583	DNA-binding transcription factor activity
APZ19_26770	COG1505	serine-type exopeptidase activity
APZ19_26775	COG4172	Belongs to the ABC transporter superfamily
APZ19_26785	COG1067	ATP-dependent peptidase activity
APZ19_26795	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
APZ19_26815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
APZ19_26820	COG0437	4 iron, 4 sulfur cluster binding
APZ19_26825	COG0348	domain, Protein
APZ19_26840	COG0640	Transcriptional regulator
APZ19_26850	COG2731	YhcH YjgK YiaL family protein
APZ19_26865	COG1122	ATPase activity
APZ19_26875	COG1566	PFAM secretion protein HlyD family protein
APZ19_26890	COG3706	GGDEF domain
APZ19_26905	COG0813	purine-nucleoside phosphorylase activity
APZ19_26915	COG3272	Protein of unknown function (DUF1722)
APZ19_26920	COG0789	Transcriptional regulator
APZ19_26925	COG0415	Belongs to the DNA photolyase family
APZ19_26930	COG1376	ErfK ybiS ycfS ynhG family protein
APZ19_26930	COG1388	LysM domain
APZ19_26940	COG0513	Belongs to the DEAD box helicase family
APZ19_26945	COG1770	oligopeptidase
APZ19_26950	COG4771	TonB-dependent receptor
APZ19_26970	COG0840	transmembrane signaling receptor activity
APZ19_26975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
APZ19_26980	COG0573	inorganic phosphate transmembrane transporter activity
APZ19_26985	COG0581	inorganic phosphate transmembrane transporter activity
APZ19_26990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
APZ19_27005	COG2304	oxidoreductase activity
APZ19_27025	COG0714	Associated with various cellular activities
APZ19_27045	COG0840	transmembrane signaling receptor activity
APZ19_27080	COG0110	maltose O-acetyltransferase activity
APZ19_27085	COG2204	response regulator
APZ19_27090	COG4191	Histidine kinase
APZ19_27100	COG0573	inorganic phosphate transmembrane transporter activity
APZ19_27110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
APZ19_27115	COG1028	Short-chain dehydrogenase reductase Sdr
APZ19_27130	COG2885	chlorophyll binding
APZ19_27130	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
APZ19_27165	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
APZ19_27170	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
APZ19_27380	COG3012	SEC-C Motif Domain Protein
APZ19_27405	COG3081	Nucleoid-associated protein
APZ19_27430	COG2842	Transposition protein
APZ19_27455	COG1301	dicarboxylic acid transport
APZ19_27465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
APZ19_27500	COG1566	PFAM secretion protein HlyD family protein
APZ19_27505	COG0583	DNA-binding transcription factor activity
APZ19_27520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APZ19_27520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
APZ19_27520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APZ19_27525	COG2207	Transcriptional regulator
APZ19_27535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APZ19_27540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
APZ19_27545	COG0583	DNA-binding transcription factor activity
APZ19_27555	COG2084	Dehydrogenase
APZ19_27560	COG0753	catalase activity
APZ19_27570	COG2130	NADP-dependent
APZ19_27575	COG1309	transcriptional regulator
APZ19_27615	COG0438	transferase activity, transferring glycosyl groups
APZ19_27640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
APZ19_27645	COG3842	ATPase activity
APZ19_27655	COG1175	transmembrane transport
APZ19_27660	COG3833	ABC-type maltose transport systems, permease component
APZ19_27690	COG2354	Protein conserved in bacteria
APZ19_27705	COG0401	homolog of Blt101
APZ19_27710	COG3217	Mosc domain protein beta barrel domain protein
APZ19_27710	COG0633	Ferredoxin
APZ19_27710	COG3217	Mosc domain protein beta barrel domain protein
APZ19_27710	COG0633	Ferredoxin
APZ19_27720	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
APZ19_27760	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
APZ19_27765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
APZ19_27775	COG0848	biopolymer transport protein
APZ19_27780	COG0811	peptide transport
APZ19_27785	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
APZ19_27795	COG3721	Heme iron utilization protein
APZ19_27800	COG0748	coenzyme F420 binding
APZ19_27815	COG0784	Response regulator, receiver
APZ19_27815	COG0835	chemotaxis
APZ19_27820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
APZ19_27825	COG0366	Alpha amylase catalytic
APZ19_27885	COG0583	DNA-binding transcription factor activity
APZ19_27900	COG2249	NAD(P)H dehydrogenase (quinone) activity
APZ19_27905	COG0583	DNA-binding transcription factor activity
APZ19_27925	COG2814	Major facilitator Superfamily
APZ19_27940	COG1335	isochorismatase
APZ19_27955	COG2194	sulfuric ester hydrolase activity
APZ19_27960	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
APZ19_27970	COG2205	protein histidine kinase activity
APZ19_27975	COG0745	RESPONSE REGULATOR receiver
APZ19_27980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
APZ19_27985	COG4948	Mandelate Racemase Muconate Lactonizing
APZ19_27990	COG1053	succinate dehydrogenase
APZ19_27990	COG3976	FMN-binding domain protein
APZ19_28000	COG4221	oxidoreductase activity
APZ19_28015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
APZ19_28035	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
APZ19_28045	COG2814	Major facilitator Superfamily
APZ19_28060	COG1418	mRNA catabolic process
APZ19_28075	COG0402	S-adenosylhomocysteine deaminase activity
APZ19_28080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
APZ19_28085	COG2239	Acts as a magnesium transporter
APZ19_28090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
APZ19_28095	COG1566	PFAM secretion protein HlyD family protein
APZ19_28120	COG0745	RESPONSE REGULATOR receiver
APZ19_28125	COG2205	protein histidine kinase activity
APZ19_28145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
APZ19_28155	COG0531	amino acid
APZ19_28160	COG1522	sequence-specific DNA binding
APZ19_28195	COG0673	inositol 2-dehydrogenase activity
APZ19_28370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APZ19_28405	COG3504	Conjugal transfer protein
APZ19_28420	COG4962	Type ii secretion system protein e
APZ19_28430	COG3451	type IV secretory pathway VirB4
APZ19_28435	COG5268	conjugation
APZ19_28460	COG1192	Involved in chromosome partitioning
APZ19_28485	COG0419	ATPase involved in DNA repair
APZ19_28595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
APZ19_28710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
APZ19_28745	COG3504	Conjugal transfer protein
APZ19_28765	COG4962	Type ii secretion system protein e
APZ19_28775	COG3451	type IV secretory pathway VirB4
APZ19_28780	COG5268	conjugation
APZ19_28810	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
APZ19_28855	COG1192	Involved in chromosome partitioning
APZ19_28915	COG2885	chlorophyll binding
APZ19_28955	COG1943	Transposase