locus-tag	class	description
D0856_00010	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D0856_00020	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D0856_00030	COG1595	DNA-templated transcription, initiation
D0856_00040	COG3026	antisigma factor binding
D0856_00045	COG3086	response to oxidative stress
D0856_00055	COG0681	Belongs to the peptidase S26 family
D0856_00065	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D0856_00070	COG1381	Involved in DNA repair and RecF pathway recombination
D0856_00075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D0856_00100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D0856_00105	COG3956	TIGRFAM MazG family protein
D0856_00115	COG0148	phosphopyruvate hydratase activity
D0856_00125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D0856_00155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D0856_00165	COG1546	Belongs to the CinA family
D0856_00170	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D0856_00185	COG0527	aspartate kinase activity
D0856_00280	COG5016	pyruvate
D0856_00280	COG0511	ligase activity, forming carbon-carbon bonds
D0856_00285	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
D0856_00295	COG1238	metal cluster binding
D0856_00300	COG0612	Peptidase, M16
D0856_00320	COG4536	flavin adenine dinucleotide binding
D0856_00325	COG4137	Cytochrome C assembly protein
D0856_00330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D0856_00335	COG0228	four-way junction DNA binding
D0856_00350	COG0335	large ribosomal subunit rRNA binding
D0856_00355	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
D0856_00360	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
D0856_00365	COG0237	dephospho-CoA kinase activity
D0856_00375	COG1459	type II secretion system
D0856_00380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0856_00385	COG4969	Belongs to the N-Me-Phe pilin family
D0856_00400	COG2186	Transcriptional regulator
D0856_00405	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D0856_00410	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0856_00415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0856_00430	COG0288	reversible hydration of carbon dioxide
D0856_00435	COG0659	secondary active sulfate transmembrane transporter activity
D0856_00440	COG1131	(ABC) transporter
D0856_00445	COG0842	Transport permease protein
D0856_00450	COG1560	Kdo2-lipid A biosynthetic process
D0856_00465	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D0856_00475	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D0856_00480	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0856_00490	COG1643	Atp-dependent helicase
D0856_00495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0856_00500	COG1752	Esterase of the alpha-beta hydrolase superfamily
D0856_00505	COG1049	propionate catabolic process, 2-methylcitrate cycle
D0856_00525	COG0004	ammonium transporteR
D0856_00530	COG1840	ABC-type Fe3 transport system, periplasmic component
D0856_00540	COG3842	ATPase activity
D0856_00545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0856_00560	COG2971	BadF BadG BcrA BcrD
D0856_00570	COG4608	Belongs to the ABC transporter superfamily
D0856_00575	COG0444	Belongs to the ABC transporter superfamily
D0856_00580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0856_00590	COG0747	negative chemotaxis
D0856_00610	COG0628	permease
D0856_00635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0856_00640	COG0739	heme binding
D0856_00645	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0856_00655	COG2027	D-alanyl-D-alanine carboxypeptidase
D0856_00660	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D0856_00665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0856_00670	COG1534	Rna-binding protein
D0856_00680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D0856_00685	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D0856_00695	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0856_00715	COG0195	Participates in both transcription termination and antitermination
D0856_00735	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D0856_00755	COG0534	Mate efflux family protein
D0856_00780	COG3153	acetyltransferase
D0856_00800	COG3706	GGDEF domain
D0856_00805	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D0856_00810	COG3620	sequence-specific DNA binding
D0856_00815	COG3550	peptidyl-serine autophosphorylation
D0856_00930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D0856_01005	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
D0856_01065	COG2204	response regulator
D0856_01070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0856_01085	COG0681	Belongs to the peptidase S26 family
D0856_01125	COG0629	single-stranded DNA binding
D0856_01140	COG0714	Associated with various cellular activities
D0856_01165	COG2003	Belongs to the UPF0758 family
D0856_01265	COG0084	hydrolase, TatD family'
D0856_01270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0856_01280	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D0856_01290	COG0813	purine-nucleoside phosphorylase activity
D0856_01300	COG0560	Phosphoserine phosphatase
D0856_01310	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D0856_01315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D0856_01320	COG0583	DNA-binding transcription factor activity
D0856_01355	COG1022	Amp-dependent synthetase and ligase
D0856_01360	COG0741	lytic transglycosylase activity
D0856_01385	COG4964	Belongs to the GSP D family
D0856_01445	COG0583	DNA-binding transcription factor activity
D0856_01450	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
D0856_01450	COG3408	Glycogen debranching enzyme
D0856_01460	COG0531	amino acid
D0856_01465	COG2731	YhcH YjgK YiaL family protein
D0856_01470	COG3250	beta-galactosidase activity
D0856_01475	COG1609	Transcriptional regulator
D0856_01480	COG0768	penicillin binding
D0856_01490	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D0856_01495	COG1085	galactose-1-phosphate uridylyltransferase
D0856_01505	COG2017	converts alpha-aldose to the beta-anomer
D0856_01515	COG1609	Transcriptional regulator
D0856_01520	COG1263	PTS System
D0856_01520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0856_01530	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0856_01550	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D0856_01555	COG1349	DNA-binding transcription factor activity
D0856_01565	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D0856_01575	COG2271	Major facilitator Superfamily
D0856_01580	COG0584	glycerophosphoryl diester phosphodiesterase
D0856_01595	COG2171	N-acyltransferase activity
D0856_01610	COG3141	response to X-ray
D0856_01630	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D0856_01640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D0856_01650	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D0856_01650	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D0856_01665	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D0856_01670	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D0856_01675	COG2166	iron-sulfur cluster assembly
D0856_01680	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0856_01685	COG0693	protein deglycase activity
D0856_01690	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D0856_01715	COG1595	DNA-templated transcription, initiation
D0856_01745	COG0271	Belongs to the BolA IbaG family
D0856_01770	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D0856_01780	COG1477	protein flavinylation
D0856_01790	COG0745	RESPONSE REGULATOR receiver
D0856_01790	COG3706	GGDEF domain
D0856_01795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0856_01800	COG0514	ATP-dependent DNA helicase (RecQ)
D0856_01805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0856_01820	COG0733	neurotransmitter:sodium symporter activity
D0856_01845	COG1720	tRNA m6t6A37 methyltransferase activity
D0856_01860	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D0856_01895	COG3098	single-species biofilm formation
D0856_01900	COG0564	pseudouridine synthase activity
D0856_01915	COG0024	Methionine aminopeptidase
D0856_01940	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D0856_01945	COG0575	Belongs to the CDS family
D0856_01955	COG0750	zinc metalloprotease
D0856_01965	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
D0856_01995	COG0587	DNA-directed DNA polymerase activity
D0856_02015	COG0347	Belongs to the P(II) protein family
D0856_02030	COG1388	LysM domain
D0856_02030	COG0741	lytic transglycosylase activity
D0856_02040	COG2226	methyltransferase
D0856_02050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D0856_02085	COG1960	acyl-CoA dehydrogenase activity
D0856_02090	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D0856_02095	COG0121	glutamine amidotransferase
D0856_02100	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D0856_02105	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D0856_02110	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D0856_02115	COG2233	PERMEase
D0856_02135	COG1393	Belongs to the ArsC family
D0856_02140	COG4783	chaperone-mediated protein folding
D0856_02155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D0856_02160	COG2716	regulation of RNA biosynthetic process
D0856_02165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0856_02190	COG1393	Belongs to the ArsC family
D0856_02215	COG2837	iron assimilation
D0856_02220	COG2169	Transcriptional regulator
D0856_02225	COG1486	melibiose metabolic process
D0856_02230	COG2211	Major facilitator Superfamily
D0856_02240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0856_02250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0856_02255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0856_02260	COG1334	flagellar protein FlaG
D0856_02265	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D0856_02275	COG1516	flagellar protein fliS
D0856_02280	COG2204	response regulator
D0856_02285	COG4191	Histidine kinase
D0856_02290	COG2204	response regulator
D0856_02295	COG1677	Flagellar hook-basal body complex protein FliE
D0856_02305	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0856_02360	COG1987	bacterial-type flagellum assembly
D0856_02365	COG1684	flagellar biosynthetic protein fliR
D0856_02385	COG0455	bacterial-type flagellum organization
D0856_02400	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
D0856_02405	COG2198	Histidine kinase
D0856_02405	COG0643	Histidine kinase
D0856_02410	COG2201	protein-glutamate methylesterase activity
D0856_02415	COG1192	Involved in chromosome partitioning
D0856_02425	COG0835	chemotaxis
D0856_02435	COG4133	protoheme IX ABC transporter activity
D0856_02440	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0856_02445	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0856_02460	COG1138	Cytochrome C-type biogenesis protein
D0856_02465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0856_02475	COG4235	cytochrome complex assembly
D0856_02475	COG3088	subunit of a heme lyase
D0856_02480	COG2853	Lipoprotein
D0856_02485	COG2067	long-chain fatty acid transport protein
D0856_02490	COG2067	long-chain fatty acid transport protein
D0856_02510	COG0183	Belongs to the thiolase family
D0856_02530	COG2062	phosphohistidine phosphatase, SixA
D0856_02535	COG2840	Smr protein MutS2
D0856_02540	COG2890	protein-(glutamine-N5) methyltransferase activity
D0856_02550	COG2860	membrane
D0856_02555	COG3101	peptidyl-lysine hydroxylation
D0856_02580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0856_02590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0856_02595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D0856_02620	COG0285	dihydrofolate synthase activity
D0856_02625	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
D0856_02630	COG1286	toxin biosynthetic process
D0856_02635	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D0856_02640	COG0583	DNA-binding transcription factor activity
D0856_02645	COG0745	RESPONSE REGULATOR receiver
D0856_02655	COG2832	Protein of unknown function (DUF454)
D0856_02665	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D0856_02675	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D0856_02680	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D0856_02685	COG0814	amino acid
D0856_02690	COG0251	oxidation-reduction process
D0856_02700	COG2964	Protein conserved in bacteria
D0856_02715	COG2983	Belongs to the UPF0260 family
D0856_02720	COG2261	transglycosylase associated protein
D0856_02725	COG2985	domain, Protein
D0856_02730	COG0076	glutamate decarboxylase activity
D0856_02735	COG0668	transmembrane transport
D0856_02745	COG0346	lactoylglutathione lyase activity
D0856_02755	COG1785	Belongs to the alkaline phosphatase family
D0856_02770	COG2226	methyltransferase
D0856_02795	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0856_02800	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0856_02810	COG3139	Protein of unknown function (DUF1315)
D0856_02815	COG0252	asparaginase activity
D0856_02820	COG0616	signal peptide processing
D0856_02825	COG1902	pentaerythritol trinitrate reductase activity
D0856_02825	COG0446	pyridine nucleotide-disulphide oxidoreductase
D0856_02830	COG0778	Nitroreductase
D0856_02835	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0856_02905	COG0123	including yeast histone deacetylase and acetoin utilization protein
D0856_02915	COG4269	membrane
D0856_02930	COG3083	sulfuric ester hydrolase activity
D0856_02955	COG1757	Na H antiporter
D0856_02960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D0856_02970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0856_02975	COG2095	MarC family integral membrane protein
D0856_02980	COG1454	alcohol dehydrogenase
D0856_02980	COG1012	belongs to the aldehyde dehydrogenase family
D0856_03000	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D0856_03010	COG2056	Na+-H+ antiporter family
D0856_03020	COG2885	chlorophyll binding
D0856_03030	COG0346	lactoylglutathione lyase activity
D0856_03040	COG0210	DNA helicase
D0856_03045	COG1196	nuclear chromosome segregation
D0856_03090	COG3293	Transposase
D0856_03150	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D0856_03155	COG4660	Part of a membrane complex involved in electron transport
D0856_03160	COG4659	FMN binding
D0856_03165	COG4658	electron transport chain
D0856_03170	COG4656	Part of a membrane complex involved in electron transport
D0856_03180	COG4657	Part of a membrane complex involved in electron transport
D0856_03185	COG1882	Formate acetyltransferase
D0856_03200	COG0556	nucleotide-excision repair
D0856_03215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D0856_03225	COG0521	Mo-molybdopterin cofactor biosynthetic process
D0856_03235	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D0856_03240	COG0314	molybdopterin synthase activity
D0856_03250	COG0601	transmembrane transport
D0856_03255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0856_03260	COG0444	Belongs to the ABC transporter superfamily
D0856_03270	COG0435	Glutathione S-transferase
D0856_03275	COG3174	membrane
D0856_03285	COG0857	belongs to the CobB CobQ family
D0856_03285	COG0280	phosphate acetyltransferase
D0856_03310	COG4120	Belongs to the binding-protein-dependent transport system permease family
D0856_03315	COG1122	ATPase activity
D0856_03320	COG0366	Alpha amylase catalytic
D0856_03325	COG3706	GGDEF domain
D0856_03330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0856_03335	COG0653	protein targeting
D0856_03340	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D0856_03350	COG2186	Transcriptional regulator
D0856_03380	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
D0856_03385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D0856_03390	COG0659	secondary active sulfate transmembrane transporter activity
D0856_03410	COG0424	maF-like protein
D0856_03415	COG1399	metal-binding, possibly nucleic acid-binding protein
D0856_03430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0856_03460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D0856_03475	COG0084	hydrolase, TatD family'
D0856_03480	COG1263	PTS System
D0856_03480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0856_03495	COG0733	neurotransmitter:sodium symporter activity
D0856_03510	COG4667	esterase of the alpha-beta hydrolase superfamily
D0856_03520	COG1940	carbohydrate kinase activity
D0856_03525	COG0784	Response regulator, receiver
D0856_03525	COG0835	chemotaxis
D0856_03545	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_03550	COG0616	signal peptide processing
D0856_03560	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D0856_03565	COG0539	negative regulation of cytoplasmic translation
D0856_03575	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
D0856_03580	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D0856_03590	COG4166	transmembrane transport
D0856_03650	COG3119	arylsulfatase activity
D0856_03655	COG1309	transcriptional regulator
D0856_03660	COG3009	Protein conserved in bacteria
D0856_03665	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D0856_03665	COG3008	intermembrane lipid transfer
D0856_03670	COG2995	paraquat-inducible protein a
D0856_03675	COG1609	Transcriptional regulator
D0856_03680	COG3258	Cytochrome c
D0856_03685	COG2863	cytochrome
D0856_03715	COG3250	beta-galactosidase activity
D0856_03725	COG4580	involved in the transport of maltose and maltodextrins
D0856_03740	COG2211	Major facilitator Superfamily
D0856_03745	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D0856_03760	COG4232	protein-disulfide reductase activity
D0856_03765	COG3118	belongs to the thioredoxin family
D0856_03775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0856_03785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0856_03790	COG3153	acetyltransferase
D0856_03830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0856_03840	COG1136	(ABC) transporter
D0856_03840	COG0577	efflux transmembrane transporter activity
D0856_03845	COG1136	(ABC) transporter
D0856_03845	COG0577	efflux transmembrane transporter activity
D0856_03850	COG0577	efflux transmembrane transporter activity
D0856_03850	COG1136	(ABC) transporter
D0856_03860	COG2176	DNA-directed DNA polymerase activity
D0856_03915	COG0583	DNA-binding transcription factor activity
D0856_03925	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0856_03985	COG5002	protein histidine kinase activity
D0856_03985	COG3850	Histidine kinase
D0856_03990	COG0745	RESPONSE REGULATOR receiver
D0856_03995	COG0463	Glycosyl transferase, family 2
D0856_04015	COG2964	Protein conserved in bacteria
D0856_04030	COG0446	pyridine nucleotide-disulphide oxidoreductase
D0856_04100	COG5001	Diguanylate cyclase
D0856_04100	COG4251	negative regulation of phosphorylation
D0856_04100	COG2203	Gaf domain
D0856_04100	COG3706	GGDEF domain
D0856_04115	COG0583	DNA-binding transcription factor activity
D0856_04130	COG2350	Protein conserved in bacteria
D0856_04135	COG1607	acyl-coa hydrolase
D0856_04165	COG0159	tryptophan synthase activity
D0856_04175	COG0134	indole-3-glycerol-phosphate synthase activity
D0856_04175	COG0135	phosphoribosylanthranilate isomerase activity
D0856_04185	COG0512	Glutamine amidotransferase of anthranilate synthase
D0856_04190	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0856_04200	COG0613	PHP domain protein
D0856_04205	COG0009	L-threonylcarbamoyladenylate synthase
D0856_04215	COG1187	pseudouridine synthase activity
D0856_04235	COG0417	DNA replication proofreading
D0856_04240	COG2197	response regulator
D0856_04285	COG0019	diaminopimelate decarboxylase activity
D0856_04300	COG1058	Belongs to the CinA family
D0856_04300	COG1546	Belongs to the CinA family
D0856_04310	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0856_04315	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0856_04325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0856_04345	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
D0856_04355	COG0437	4 iron, 4 sulfur cluster binding
D0856_04360	COG3301	Polysulphide reductase, NrfD
D0856_04365	COG1138	Cytochrome C-type biogenesis protein
D0856_04375	COG3088	subunit of a heme lyase
D0856_04375	COG4235	cytochrome complex assembly
D0856_04385	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0856_04410	COG2989	Protein conserved in bacteria
D0856_04415	COG3108	Peptidase M15
D0856_04420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0856_04435	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D0856_04460	COG1846	Transcriptional regulator
D0856_04465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0856_04490	COG1448	Aminotransferase
D0856_04495	COG3437	response regulator, receiver
D0856_04495	COG2770	Histidine kinase
D0856_04500	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0856_04510	COG1609	Transcriptional regulator
D0856_04525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0856_04540	COG0017	Asparaginyl-tRNA synthetase
D0856_04550	COG0720	synthase
D0856_04555	COG2197	response regulator
D0856_04565	COG5001	Diguanylate cyclase
D0856_04565	COG3300	MHYT domain
D0856_04570	COG1760	l-serine dehydratase
D0856_04575	COG0814	amino acid
D0856_04595	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0856_04610	COG3106	COG3106 Predicted ATPase
D0856_04625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0856_04855	COG0110	maltose O-acetyltransferase activity
D0856_04875	COG0791	NLP P60 protein
D0856_05530	COG1335	isochorismatase
D0856_05820	COG1733	regulation of RNA biosynthetic process
D0856_05830	COG3340	Belongs to the peptidase S51 family
D0856_05850	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0856_05875	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D0856_05880	COG1609	Transcriptional regulator
D0856_05920	COG0456	acetyltransferase
D0856_05925	COG0471	metal ion transport
D0856_05930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0856_05930	COG4191	Histidine kinase
D0856_05940	COG3300	MHYT domain
D0856_05940	COG5001	Diguanylate cyclase
D0856_05950	COG1280	lysine exporter protein (LysE YggA)
D0856_05955	COG1328	CTP reductase activity
D0856_05960	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D0856_05970	COG0861	Integral membrane protein TerC family
D0856_05980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D0856_05985	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_05990	COG3706	GGDEF domain
D0856_06005	COG0814	amino acid
D0856_06025	COG1132	(ABC) transporter
D0856_06030	COG1132	(ABC) transporter
D0856_06045	COG0583	DNA-binding transcription factor activity
D0856_06050	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D0856_06070	COG0443	Heat shock 70 kDa protein
D0856_06075	COG0443	Heat shock 70 kDa protein
D0856_06085	COG3706	GGDEF domain
D0856_06110	COG3227	Zinc metalloprotease (Elastase)
D0856_06120	COG0243	molybdopterin cofactor binding
D0856_06125	COG0437	4 iron, 4 sulfur cluster binding
D0856_06130	COG3302	dmso reductase anchor subunit
D0856_06145	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D0856_06150	COG1643	Atp-dependent helicase
D0856_06175	COG3063	Type IV pilus biogenesis stability protein PilW
D0856_06210	COG0531	amino acid
D0856_06215	COG1280	lysine exporter protein (LysE YggA)
D0856_06220	COG0583	DNA-binding transcription factor activity
D0856_06225	COG0702	epimerase
D0856_06230	COG0583	DNA-binding transcription factor activity
D0856_06235	COG1560	Kdo2-lipid A biosynthetic process
D0856_06250	COG1846	Transcriptional regulator
D0856_06285	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D0856_06290	COG1280	lysine exporter protein (LysE YggA)
D0856_06320	COG1115	amino acid carrier protein
D0856_06375	COG0583	DNA-binding transcription factor activity
D0856_06380	COG1368	sulfuric ester hydrolase activity
D0856_06385	COG0215	cysteine-tRNA ligase activity
D0856_06390	COG0534	Mate efflux family protein
D0856_06395	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
D0856_06405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0856_06410	COG0456	acetyltransferase
D0856_06415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D0856_06420	COG0662	Cupin 2, conserved barrel domain protein
D0856_06425	COG0527	aspartate kinase activity
D0856_06440	COG0583	DNA-binding transcription factor activity
D0856_06445	COG1858	cytochrome C peroxidase
D0856_06455	COG2814	Major facilitator Superfamily
D0856_06460	COG1404	Belongs to the peptidase S8 family
D0856_06465	COG0583	DNA-binding transcription factor activity
D0856_06470	COG0702	epimerase
D0856_06530	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
D0856_06560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0856_06575	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D0856_06580	COG3290	protein histidine kinase activity
D0856_06585	COG4565	transcriptional regulatory protein
D0856_06590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D0856_06595	COG0363	glucosamine-6-phosphate deaminase activity
D0856_06600	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D0856_06630	COG3284	Transcriptional regulator
D0856_06635	COG1012	belongs to the aldehyde dehydrogenase family
D0856_06640	COG1902	pentaerythritol trinitrate reductase activity
D0856_06650	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0856_06660	COG0840	transmembrane signaling receptor activity
D0856_06665	COG0730	response to heat
D0856_06700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D0856_06705	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D0856_06800	COG3501	Rhs element vgr protein
D0856_06815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D0856_06820	COG0372	Belongs to the citrate synthase family
D0856_06830	COG2828	Protein conserved in bacteria
D0856_06855	COG0561	phosphatase activity
D0856_06860	COG0602	queuosine metabolic process
D0856_06870	COG3706	GGDEF domain
D0856_06925	COG0840	transmembrane signaling receptor activity
D0856_06930	COG1254	Belongs to the acylphosphatase family
D0856_06935	COG2920	part of a sulfur-relay system
D0856_06945	COG0670	Belongs to the BI1 family
D0856_06950	COG1126	abc transporter atp-binding protein
D0856_06955	COG0765	amino acid transport
D0856_06960	COG4597	amino acid ABC transporter
D0856_06965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0856_06985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D0856_07035	COG0793	Belongs to the peptidase S41A family
D0856_07055	COG2902	Dehydrogenase
D0856_07220	COG2010	Cytochrome c
D0856_07245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0856_07250	COG0589	response to stress
D0856_07275	COG3842	ATPase activity
D0856_07280	COG1176	ABC-type spermidine putrescine transport system, permease component I
D0856_07285	COG1177	transmembrane transport
D0856_07290	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D0856_07295	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D0856_07300	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D0856_07315	COG0437	4 iron, 4 sulfur cluster binding
D0856_07320	COG0243	molybdopterin cofactor binding
D0856_07320	COG3383	formate dehydrogenase (NAD+) activity
D0856_07330	COG3381	protein complex oligomerization
D0856_07350	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D0856_07355	COG0488	(ABC) transporter
D0856_07375	COG4191	Histidine kinase
D0856_07380	COG2204	response regulator
D0856_07390	COG4662	Binding-protein-dependent transport system inner membrane component
D0856_07395	COG3842	ATPase activity
D0856_07405	COG0303	'Molybdopterin
D0856_07420	COG1940	carbohydrate kinase activity
D0856_07465	COG0840	transmembrane signaling receptor activity
D0856_07470	COG0791	NLP P60 protein
D0856_07480	COG3706	GGDEF domain
D0856_07485	COG2201	protein-glutamate methylesterase activity
D0856_07500	COG0307	riboflavin synthase, alpha
D0856_07505	COG0534	Mate efflux family protein
D0856_07515	COG1793	dna ligase
D0856_07525	COG2885	chlorophyll binding
D0856_07545	COG2204	response regulator
D0856_07595	COG0297	glycogen (starch) synthase activity
D0856_07600	COG1215	transferase activity, transferring glycosyl groups
D0856_07605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D0856_07615	COG3064	Membrane
D0856_07640	COG3300	MHYT domain
D0856_07640	COG5001	Diguanylate cyclase
D0856_07645	COG4999	Histidine kinase
D0856_07645	COG3437	response regulator, receiver
D0856_07645	COG2205	protein histidine kinase activity
D0856_07645	COG3850	Histidine kinase
D0856_07665	COG0110	maltose O-acetyltransferase activity
D0856_07695	COG2315	Protein conserved in bacteria
D0856_07700	COG1846	Transcriptional regulator
D0856_07780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D0856_07785	COG3247	response to pH
D0856_07790	COG0668	transmembrane transport
D0856_07910	COG0519	Catalyzes the synthesis of GMP from XMP
D0856_07915	COG0589	response to stress
D0856_07930	COG0583	DNA-binding transcription factor activity
D0856_07945	COG3083	sulfuric ester hydrolase activity
D0856_07955	COG0583	DNA-binding transcription factor activity
D0856_07960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0856_07970	COG0583	DNA-binding transcription factor activity
D0856_07975	COG0668	transmembrane transport
D0856_08000	COG1401	restriction endodeoxyribonuclease activity
D0856_08115	COG0625	glutathione transferase activity
D0856_08125	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
D0856_08145	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0856_08155	COG3706	GGDEF domain
D0856_08155	COG0745	RESPONSE REGULATOR receiver
D0856_08165	COG1451	nucleotide metabolic process
D0856_08175	COG4932	domain protein
D0856_08175	COG5492	domain, Protein
D0856_08190	COG2204	response regulator
D0856_08275	COG0583	DNA-binding transcription factor activity
D0856_08305	COG4139	cobalamin transport
D0856_08320	COG2062	phosphohistidine phosphatase, SixA
D0856_08330	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D0856_08340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D0856_08345	COG0702	epimerase
D0856_08360	COG2925	Exonuclease
D0856_08415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0856_08420	COG1621	beta-fructofuranosidase activity
D0856_08430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0856_08430	COG0072	phenylalanine-tRNA ligase activity
D0856_08440	COG3706	GGDEF domain
D0856_08480	COG0251	oxidation-reduction process
D0856_08500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D0856_08525	COG2188	Transcriptional regulator
D0856_08535	COG0010	Belongs to the arginase family
D0856_08545	COG2986	histidine ammonia-lyase
D0856_08565	COG0277	FAD linked oxidase domain protein
D0856_08565	COG0247	lactate metabolic process
D0856_08620	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
D0856_08625	COG1643	Atp-dependent helicase
D0856_08635	COG2949	membrane
D0856_08640	COG0471	metal ion transport
D0856_08645	COG3706	GGDEF domain
D0856_08665	COG0492	ferredoxin-NADP+ reductase activity
D0856_08670	COG4988	ABC transporter
D0856_08675	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D0856_08685	COG0583	DNA-binding transcription factor activity
D0856_08690	COG2200	EAL domain
D0856_08730	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D0856_08740	COG4191	Histidine kinase
D0856_08740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0856_08755	COG3070	regulator of competence-specific genes
D0856_08770	COG2431	L-lysine efflux transmembrane transporter activity
D0856_08780	COG0076	glutamate decarboxylase activity
D0856_08785	COG1737	Transcriptional regulator
D0856_08795	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D0856_08805	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D0856_08840	COG0534	Mate efflux family protein
D0856_08845	COG0702	epimerase
D0856_08850	COG4667	esterase of the alpha-beta hydrolase superfamily
D0856_08860	COG2814	Major facilitator Superfamily
D0856_08865	COG1187	pseudouridine synthase activity
D0856_08870	COG1061	Type III restriction enzyme res subunit
D0856_08885	COG0745	RESPONSE REGULATOR receiver
D0856_08975	COG2310	stress, protein
D0856_08990	COG3313	Fe-S protein
D0856_09000	COG0659	secondary active sulfate transmembrane transporter activity
D0856_09025	COG0493	'glutamate synthase
D0856_09035	COG0398	Pfam SNARE associated Golgi protein
D0856_09040	COG4134	Bacterial extracellular solute-binding protein
D0856_09045	COG4135	transport system, permease component
D0856_09050	COG4136	ATPase activity
D0856_09055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D0856_09065	COG1151	hydroxylamine reductase activity
D0856_09070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0856_09080	COG0564	pseudouridine synthase activity
D0856_09090	COG0733	neurotransmitter:sodium symporter activity
D0856_09100	COG0626	cystathionine gamma-synthase activity
D0856_09105	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D0856_09115	COG2818	Glycosylase
D0856_09135	COG1983	PspC domain protein
D0856_09145	COG1842	Phage shock protein A
D0856_09150	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D0856_09160	COG4168	peptide transport system, permease
D0856_09165	COG4171	peptide transport system, permease
D0856_09175	COG4172	Belongs to the ABC transporter superfamily
D0856_09185	COG1227	inorganic diphosphatase activity
D0856_09200	COG0243	molybdopterin cofactor binding
D0856_09205	COG3005	denitrification pathway
D0856_09210	COG4459	periplasmic nitrate reductase
D0856_09215	COG0390	transport system, permease component
D0856_09220	COG2116	formate transmembrane transporter activity
D0856_09245	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D0856_09250	COG1435	thymidine kinase activity
D0856_09255	COG0215	cysteine-tRNA ligase activity
D0856_09260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D0856_09265	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D0856_09270	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D0856_09275	COG3012	SEC-C Motif Domain Protein
D0856_09280	COG0140	phosphoribosyl-ATP diphosphatase activity
D0856_09280	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D0856_09285	COG0107	imidazoleglycerol-phosphate synthase activity
D0856_09290	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D0856_09295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D0856_09300	COG0131	Imidazoleglycerol-phosphate dehydratase
D0856_09300	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D0856_09310	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D0856_09320	COG1757	Na H antiporter
D0856_09330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0856_09350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D0856_09360	COG2268	Band 7 protein
D0856_09370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D0856_09385	COG0300	oxidoreductase activity
D0856_09430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0856_09450	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D0856_09460	COG1674	ftsk spoiiie
D0856_09470	COG0686	Belongs to the AlaDH PNT family
D0856_09480	COG0583	DNA-binding transcription factor activity
D0856_09500	COG0800	Aldolase
D0856_09505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0856_09510	COG1917	Cupin 2, conserved barrel domain protein
D0856_09540	COG0402	S-adenosylhomocysteine deaminase activity
D0856_09550	COG3181	Tripartite tricarboxylate transporter family receptor
D0856_09565	COG4934	collagen metabolic process
D0856_09585	COG3568	Endonuclease Exonuclease Phosphatase
D0856_09625	COG2199	diguanylate cyclase activity
D0856_09630	COG3477	response to acidic pH
D0856_09645	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_09650	COG1917	Cupin 2, conserved barrel domain protein
D0856_09660	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0856_09665	COG1904	glucuronate isomerase
D0856_09690	COG2186	Transcriptional regulator
D0856_09695	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_09700	COG2186	Transcriptional regulator
D0856_09705	COG0517	IMP dehydrogenase activity
D0856_09710	COG2176	DNA-directed DNA polymerase activity
D0856_09720	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
D0856_09735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0856_09760	COG1120	ATPase activity
D0856_09765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0856_09770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0856_09790	COG1288	antiporter activity
D0856_09800	COG2186	Transcriptional regulator
D0856_09810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0856_09815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0856_09850	COG2076	Multidrug Resistance protein
D0856_09865	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0856_09890	COG0444	Belongs to the ABC transporter superfamily
D0856_09895	COG0534	Mate efflux family protein
D0856_09920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0856_09925	COG2824	Alkylphosphonate utilization operon protein PhnA
D0856_09935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0856_09935	COG1263	PTS System
D0856_09945	COG3119	arylsulfatase activity
D0856_10055	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0856_10060	COG4790	Type iii secretion
D0856_10065	COG4794	Type iii secretion
D0856_10070	COG4791	protein targeting
D0856_10075	COG4792	protein secretion
D0856_10090	COG3177	Filamentation induced by cAMP protein fic
D0856_10120	COG4669	(LipO)protein
D0856_10205	COG5002	protein histidine kinase activity
D0856_10205	COG0784	Response regulator, receiver
D0856_10215	COG0754	glutathionylspermidine amidase activity
D0856_10225	COG3766	membrane
D0856_10240	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
D0856_10245	COG2885	chlorophyll binding
D0856_10250	COG0823	Involved in the tonB-independent uptake of proteins
D0856_10265	COG0811	peptide transport
D0856_10270	COG0824	Thioesterase
D0856_10280	COG4890	Cyd operon protein YbgT
D0856_10285	COG1294	oxidase, subunit
D0856_10290	COG1271	oxidase subunit
D0856_10300	COG0632	four-way junction helicase activity
D0856_10305	COG0840	transmembrane signaling receptor activity
D0856_10320	COG1801	Protein of unknown function DUF72
D0856_10340	COG0189	ligase activity
D0856_10340	COG4067	protein conserved in archaea
D0856_10370	COG0318	PFAM AMP-dependent synthetase and ligase
D0856_10385	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D0856_10390	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
D0856_10400	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0856_10405	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D0856_10410	COG0745	RESPONSE REGULATOR receiver
D0856_10425	COG3070	regulator of competence-specific genes
D0856_10445	COG0297	glycogen (starch) synthase activity
D0856_10450	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0856_10455	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0856_10485	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D0856_10490	COG0542	response to heat
D0856_10500	COG1278	Cold shock
D0856_10510	COG1187	pseudouridine synthase activity
D0856_10515	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
D0856_10525	COG1199	ATP-dependent helicase activity
D0856_10535	COG3923	Primosomal replication protein n
D0856_10550	COG0708	Exodeoxyribonuclease III
D0856_10560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0856_10575	COG4215	(ABC) transporter
D0856_10600	COG1882	Formate acetyltransferase
D0856_10610	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D0856_10630	COG2766	serine protein kinase
D0856_10635	COG2718	Belongs to the UPF0229 family
D0856_10640	COG2719	SpoVR family
D0856_10660	COG1132	(ABC) transporter
D0856_10675	COG4591	ABC-type transport system involved in lipoprotein release permease component
D0856_10680	COG1136	(ABC) transporter
D0856_10685	COG4591	ABC-type transport system involved in lipoprotein release permease component
D0856_10710	COG1252	NADH dehydrogenase
D0856_10740	COG0537	adenosine 5'-monophosphoramidase activity
D0856_10760	COG2217	Heavy metal translocating P-type atpase
D0856_10810	COG4397	Mu-like prophage major head subunit gpT
D0856_10815	COG3941	tape measure
D0856_10825	COG0517	IMP dehydrogenase activity
D0856_10825	COG0516	GMP reductase activity
D0856_10830	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
D0856_10835	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D0856_10840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0856_10845	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D0856_10890	COG2199	diguanylate cyclase activity
D0856_10905	COG3126	Type III secretion system lipoprotein chaperone (YscW)
D0856_10910	COG1946	Acyl-CoA thioesterase
D0856_10920	COG1522	sequence-specific DNA binding
D0856_10995	COG2855	membrane
D0856_11005	COG0583	DNA-binding transcription factor activity
D0856_11010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0856_11010	COG1263	PTS System
D0856_11010	COG2190	(PTS) system
D0856_11020	COG1441	menaquinone biosynthetic process
D0856_11025	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D0856_11030	COG0596	Alpha beta hydrolase
D0856_11040	COG1169	isochorismate synthase
D0856_11045	COG0436	Aminotransferase
D0856_11050	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
D0856_11070	COG1555	photosystem II stabilization
D0856_11075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0856_11080	COG0776	regulation of translation
D0856_11085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D0856_11120	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D0856_11125	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D0856_11130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D0856_11150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0856_11155	COG0569	domain protein
D0856_11160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0856_11165	COG0513	Belongs to the DEAD box helicase family
D0856_11170	COG1253	flavin adenine dinucleotide binding
D0856_11175	COG4771	TonB-dependent receptor
D0856_11190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0856_11190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D0856_11195	COG1535	isochorismatase
D0856_11195	COG3433	isochorismatase activity
D0856_11200	COG1021	2,3-dihydroxybenzoate-AMP ligase
D0856_11205	COG1169	isochorismate synthase
D0856_11215	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_11245	COG2852	Protein conserved in bacteria
D0856_11250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0856_11260	COG2951	lytic endotransglycosylase activity
D0856_11275	COG2894	cell division
D0856_11280	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
D0856_11285	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
D0856_11290	COG0318	PFAM AMP-dependent synthetase and ligase
D0856_11295	COG2267	carboxylic ester hydrolase activity
D0856_11300	COG3065	identical protein binding
D0856_11310	COG1214	PFAM Peptidase M22, glycoprotease
D0856_11315	COG1199	ATP-dependent helicase activity
D0856_11320	COG0788	formyltetrahydrofolate deformylase activity
D0856_11325	COG3102	Protein conserved in bacteria
D0856_11355	COG1918	ferrous iron import across plasma membrane
D0856_11365	COG4977	sequence-specific DNA binding
D0856_11370	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
D0856_11375	COG1121	(ABC) transporter
D0856_11380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0856_11395	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0856_11400	COG0567	Dehydrogenase, E1 component
D0856_11410	COG1053	succinate dehydrogenase
D0856_11415	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D0856_11420	COG2009	succinate dehydrogenase
D0856_11430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D0856_11445	COG0033	Phosphoglucomutase
D0856_11455	COG0596	Alpha beta hydrolase
D0856_11465	COG0716	FMN binding
D0856_11475	COG0735	belongs to the Fur family
D0856_11480	COG2165	general secretion pathway protein
D0856_11490	COG2190	(PTS) system
D0856_11490	COG1263	PTS System
D0856_11490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0856_11500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D0856_11505	COG1846	Transcriptional regulator
D0856_11505	COG1940	carbohydrate kinase activity
D0856_11510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D0856_11510	COG4651	solute:proton antiporter activity
D0856_11515	COG0367	asparagine synthase
D0856_11520	COG0250	Participates in transcription elongation, termination and antitermination
D0856_11525	COG3104	oligopeptide transport
D0856_11530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D0856_11545	COG3710	Transcriptional regulator
D0856_11565	COG0622	Phosphoesterase
D0856_11595	COG1090	epimerase
D0856_11600	COG0300	oxidoreductase activity
D0856_11610	COG3118	belongs to the thioredoxin family
D0856_11615	COG3118	belongs to the thioredoxin family
D0856_11615	COG0457	Tetratricopeptide repeat
D0856_11620	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
D0856_11625	COG1215	transferase activity, transferring glycosyl groups
D0856_11630	COG1215	transferase activity, transferring glycosyl groups
D0856_11650	COG2194	sulfuric ester hydrolase activity
D0856_11655	COG0330	HflC and HflK could
D0856_11695	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
D0856_11700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0856_11710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0856_11715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D0856_11720	COG2190	(PTS) system
D0856_11725	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0856_11730	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0856_11735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0856_11750	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0856_11750	COG3951	Flagellar rod assembly protein muramidase FlgJ
D0856_11755	COG1706	bacterial-type flagellum-dependent cell motility
D0856_11760	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
D0856_11765	COG4786	Flagellar basal body rod
D0856_11770	COG4787	bacterial-type flagellum-dependent cell motility
D0856_11775	COG1749	Flagellar hook protein flgE
D0856_11780	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D0856_11785	COG1558	bacterial-type flagellum-dependent cell motility
D0856_11790	COG1815	bacterial-type flagellum-dependent cell motility
D0856_11795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D0856_11800	COG0835	chemotaxis
D0856_11800	COG0784	Response regulator, receiver
D0856_11855	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
D0856_11870	COG2217	Heavy metal translocating P-type atpase
D0856_11870	COG2608	mercury ion transmembrane transporter activity
D0856_11905	COG2840	Smr protein MutS2
D0856_11910	COG1187	pseudouridine synthase activity
D0856_11915	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D0856_11920	COG0737	Belongs to the 5'-nucleotidase family
D0856_11930	COG2912	Transglutaminase-like superfamily
D0856_11935	COG3094	Invasion gene expression up-regulator, SirB
D0856_11940	COG2890	protein-(glutamine-N5) methyltransferase activity
D0856_11965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D0856_12085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0856_12100	COG1702	phosphate starvation-inducible protein PhoH
D0856_12110	COG4535	Mg2 and Co2 transporter CorC
D0856_12115	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D0856_12120	COG2888	peptidyl-tyrosine sulfation
D0856_12125	COG0495	leucyl-tRNA aminoacylation
D0856_12130	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
D0856_12135	COG1466	dna polymerase III delta subunit
D0856_12140	COG0799	negative regulation of ribosome biogenesis
D0856_12150	COG0768	penicillin binding
D0856_12155	COG0772	Belongs to the SEDS family
D0856_12160	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D0856_12165	COG1686	Belongs to the peptidase S11 family
D0856_12185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D0856_12190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0856_12205	COG0366	Alpha amylase catalytic
D0856_12210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0856_12210	COG1263	PTS System
D0856_12220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D0856_12225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D0856_12230	COG2011	ABC-type metal ion transport system permease component
D0856_12235	COG1464	Belongs to the NlpA lipoprotein family
D0856_12245	COG0737	Belongs to the 5'-nucleotidase family
D0856_12250	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
D0856_12270	COG0745	RESPONSE REGULATOR receiver
D0856_12270	COG3706	GGDEF domain
D0856_12275	COG1611	Belongs to the LOG family
D0856_12290	COG2363	Small membrane protein
D0856_12300	COG0583	DNA-binding transcription factor activity
D0856_12315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D0856_12325	COG0142	geranyltranstransferase activity
D0856_12335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D0856_12340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D0856_12365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0856_12365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0856_12370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D0856_12375	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D0856_12400	COG2252	PERMEase
D0856_12405	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0856_12455	COG0590	tRNA wobble adenosine to inosine editing
D0856_12460	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D0856_12505	COG1301	dicarboxylic acid transport
D0856_12525	COG0497	DNA recombination
D0856_12530	COG0456	acetyltransferase
D0856_12535	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0856_12545	COG2914	Belongs to the UPF0125 (RnfH) family
D0856_12550	COG2867	negative regulation of translational initiation
D0856_12565	COG0583	DNA-binding transcription factor activity
D0856_12570	COG1289	transmembrane transporter activity
D0856_12590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D0856_12595	COG2873	o-acetylhomoserine
D0856_12600	COG0668	transmembrane transport
D0856_12615	COG0583	DNA-binding transcription factor activity
D0856_12625	COG1115	amino acid carrier protein
D0856_12630	COG1584	GPR1 FUN34 yaaH family protein
D0856_12640	COG1757	Na H antiporter
D0856_12650	COG0516	GMP reductase activity
D0856_12650	COG0517	IMP dehydrogenase activity
D0856_12665	COG2203	Gaf domain
D0856_12665	COG2199	diguanylate cyclase activity
D0856_12680	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0856_12685	COG2976	Protein conserved in bacteria
D0856_12720	COG2975	iron-sulfur cluster assembly
D0856_12725	COG0633	Ferredoxin
D0856_12740	COG0316	Belongs to the HesB IscA family
D0856_12745	COG0822	iron-sulfur transferase activity
D0856_12760	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
D0856_12765	COG0483	inositol monophosphate 1-phosphatase activity
D0856_12770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0856_12775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0856_12780	COG1862	Preprotein translocase
D0856_12805	COG0517	IMP dehydrogenase activity
D0856_12815	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D0856_12820	COG0583	DNA-binding transcription factor activity
D0856_12825	COG0450	alkyl hydroperoxide reductase
D0856_12855	COG0704	Plays a role in the regulation of phosphate uptake
D0856_12860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0856_12870	COG0573	inorganic phosphate transmembrane transporter activity
D0856_12875	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D0856_12880	COG0248	Ppx GppA phosphatase
D0856_12890	COG5002	protein histidine kinase activity
D0856_12895	COG0745	RESPONSE REGULATOR receiver
D0856_12910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D0856_12970	COG0542	response to heat
D0856_12980	COG0564	pseudouridine synthase activity
D0856_12985	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0856_12990	COG0741	lytic transglycosylase activity
D0856_12995	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D0856_13000	COG1605	Chorismate mutase
D0856_13000	COG0077	Prephenate dehydratase
D0856_13005	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
D0856_13020	COG0488	(ABC) transporter
D0856_13030	COG0739	heme binding
D0856_13035	COG1605	Chorismate mutase
D0856_13035	COG0287	Prephenate dehydrogenase
D0856_13040	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D0856_13045	COG1472	Belongs to the glycosyl hydrolase 3 family
D0856_13050	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
D0856_13070	COG1966	Carbon starvation protein
D0856_13075	COG3275	phosphorelay sensor kinase activity
D0856_13080	COG3279	Response regulator of the LytR AlgR family
D0856_13085	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D0856_13090	COG1047	Peptidyl-prolyl cis-trans
D0856_13105	COG0196	riboflavin kinase activity
D0856_13110	COG0728	peptidoglycan biosynthetic process
D0856_13115	COG0268	Binds directly to 16S ribosomal RNA
D0856_13120	COG0640	Transcriptional regulator
D0856_13125	COG0583	DNA-binding transcription factor activity
D0856_13130	COG1283	sodium-dependent phosphate transmembrane transporter activity
D0856_13150	COG0730	response to heat
D0856_13175	COG0667	Aldo Keto reductase
D0856_13200	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D0856_13205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0856_13215	COG0716	FMN binding
D0856_13230	COG0513	Belongs to the DEAD box helicase family
D0856_13240	COG3022	response to hydroperoxide
D0856_13245	COG1115	amino acid carrier protein
D0856_13280	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D0856_13285	COG0083	homoserine kinase activity
D0856_13300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D0856_13315	COG0745	RESPONSE REGULATOR receiver
D0856_13325	COG0784	Response regulator, receiver
D0856_13325	COG2198	Histidine kinase
D0856_13325	COG5002	protein histidine kinase activity
D0856_13330	COG4251	negative regulation of phosphorylation
D0856_13330	COG3706	GGDEF domain
D0856_13330	COG5001	Diguanylate cyclase
D0856_13330	COG2203	Gaf domain
D0856_13335	COG1242	4 iron, 4 sulfur cluster binding
D0856_13340	COG0070	glutamate synthase
D0856_13340	COG0069	glutamate synthase activity
D0856_13340	COG0067	glutamate synthase
D0856_13350	COG0070	glutamate synthase
D0856_13350	COG0069	glutamate synthase activity
D0856_13350	COG0067	glutamate synthase
D0856_13355	COG0493	'glutamate synthase
D0856_13380	COG2860	membrane
D0856_13385	COG0583	DNA-binding transcription factor activity
D0856_13390	COG0730	response to heat
D0856_13405	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D0856_13410	COG0505	Belongs to the CarA family
D0856_13420	COG0494	nUDIX hydrolase
D0856_13440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D0856_13445	COG0849	cell division
D0856_13450	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D0856_13465	COG0772	Belongs to the SEDS family
D0856_13480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D0856_13485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D0856_13490	COG0768	penicillin binding
D0856_13495	COG3116	cell division
D0856_13515	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D0856_13530	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D0856_13535	COG2823	Periplasmic or secreted lipoprotein
D0856_13540	COG2969	positive regulation of protein catabolic process
D0856_13545	COG0625	glutathione transferase activity
D0856_13550	COG2857	Cytochrome c1
D0856_13555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D0856_13560	COG0723	plastoquinol--plastocyanin reductase activity
D0856_13580	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D0856_13590	COG3105	Protein conserved in bacteria
D0856_13595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0856_13600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0856_13605	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D0856_13610	COG0187	DNA topoisomerase II activity
D0856_13615	COG3150	esterase
D0856_13625	COG3151	Protein conserved in bacteria
D0856_13630	COG0494	nUDIX hydrolase
D0856_13635	COG1538	Outer membrane efflux protein
D0856_13645	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D0856_13655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D0856_13660	COG3025	triphosphatase activity
D0856_13665	COG1392	Phosphate transport regulator
D0856_13670	COG0306	phosphate transporter
D0856_13675	COG4991	sh3 domain protein
D0856_13680	COG0405	Gamma-glutamyltransferase
D0856_13695	COG3409	Peptidoglycan-binding domain 1 protein
D0856_13695	COG3267	Type II secretory pathway component ExeA
D0856_13710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D0856_13715	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D0856_13725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D0856_13730	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D0856_13735	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D0856_13740	COG1610	YqeY-like protein
D0856_13745	COG0358	DNA primase activity
D0856_13750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D0856_13825	COG0582	viral genome integration into host DNA
D0856_13850	COG2213	PTS system mannitol-specific
D0856_13850	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0856_13860	COG3722	fumarate hydratase activity
D0856_13865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0856_13870	COG5002	protein histidine kinase activity
D0856_13890	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D0856_13895	COG1349	DNA-binding transcription factor activity
D0856_13905	COG0469	pyruvate kinase activity
D0856_13915	COG3706	GGDEF domain
D0856_13920	COG0440	acetolactate synthase activity
D0856_13925	COG0028	Belongs to the TPP enzyme family
D0856_13930	COG1022	Amp-dependent synthetase and ligase
D0856_13935	COG0583	DNA-binding transcription factor activity
D0856_13965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D0856_13970	COG0473	3-isopropylmalate dehydrogenase activity
D0856_13990	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D0856_13995	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D0856_14000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0856_14005	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D0856_14030	COG3610	response to peptide
D0856_14035	COG2966	Psort location CytoplasmicMembrane, score
D0856_14050	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D0856_14055	COG0142	geranyltranstransferase activity
D0856_14095	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
D0856_14100	COG1178	ABC-type Fe3 transport system permease component
D0856_14105	COG4143	(ABC) transporter
D0856_14110	COG0163	prenyltransferase activity
D0856_14115	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D0856_14125	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D0856_14140	COG2105	PFAM AIG2 family protein
D0856_14150	COG0729	surface antigen
D0856_14155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0856_14165	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
D0856_14180	COG1136	(ABC) transporter
D0856_14200	COG0529	Catalyzes the synthesis of activated sulfate
D0856_14205	COG3273	potassium ion transport
D0856_14205	COG0471	metal ion transport
D0856_14220	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D0856_14220	COG1648	precorrin-2 dehydrogenase activity
D0856_14225	COG0737	Belongs to the 5'-nucleotidase family
D0856_14240	COG0513	Belongs to the DEAD box helicase family
D0856_14245	COG2153	protein acetylation
D0856_14260	COG0545	Peptidyl-prolyl cis-trans isomerase
D0856_14270	COG0203	ribosomal protein L17
D0856_14275	COG0202	RNA polymerase activity
D0856_14285	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D0856_14290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D0856_14300	COG0201	protein transport
D0856_14310	COG1841	ribosomal large subunit assembly
D0856_14340	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D0856_14375	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D0856_14410	COG0254	rRNA binding
D0856_14420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D0856_14425	COG1609	Transcriptional regulator
D0856_14445	COG1575	Belongs to the MenA family. Type 1 subfamily
D0856_14450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D0856_14460	COG1494	fructose-1,6-bisphosphatase
D0856_14485	COG0149	triose-phosphate isomerase activity
D0856_14490	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D0856_14505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D0856_14515	COG1215	transferase activity, transferring glycosyl groups
D0856_14530	COG0297	glycogen (starch) synthase activity
D0856_14530	COG0438	transferase activity, transferring glycosyl groups
D0856_14625	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0856_14635	COG1560	Kdo2-lipid A biosynthetic process
D0856_14645	COG1519	Transferase
D0856_14665	COG2089	acid synthase
D0856_14675	COG1083	cytidylyl-transferase
D0856_14680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0856_14685	COG1086	Polysaccharide biosynthesis protein
D0856_14690	COG3642	lipopolysaccharide core region biosynthetic process
D0856_14695	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D0856_14700	COG0859	PFAM glycosyl transferase family 9
D0856_14705	COG0463	Glycosyl transferase, family 2
D0856_14710	COG0438	transferase activity, transferring glycosyl groups
D0856_14760	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D0856_14770	COG1560	Kdo2-lipid A biosynthetic process
D0856_14780	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D0856_14785	COG1561	YicC-like family, N-terminal region
D0856_14790	COG0745	RESPONSE REGULATOR receiver
D0856_14815	COG4608	Belongs to the ABC transporter superfamily
D0856_14820	COG0444	Belongs to the ABC transporter superfamily
D0856_14825	COG0747	negative chemotaxis
D0856_14830	COG4239	(ABC) transporter, permease
D0856_14835	COG4174	ABC transporter (Permease)
D0856_14860	COG0811	peptide transport
D0856_14865	COG0848	biopolymer transport protein
D0856_14880	COG0194	GDP metabolic process
D0856_14885	COG1758	RNA polymerase activity
D0856_14890	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D0856_14895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0856_14900	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D0856_14910	COG2233	PERMEase
D0856_14915	COG2205	protein histidine kinase activity
D0856_14920	COG0745	RESPONSE REGULATOR receiver
D0856_14925	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0856_14935	COG2183	response to ionizing radiation
D0856_14950	COG1040	competence protein
D0856_14960	COG0494	nUDIX hydrolase
D0856_14965	COG1218	3'(2'),5'-bisphosphate nucleotidase
D0856_14975	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
D0856_14980	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
D0856_14985	COG3156	type II secretion system protein K
D0856_14990	COG4795	General secretion pathway protein
D0856_14995	COG2165	general secretion pathway protein
D0856_15000	COG2165	general secretion pathway protein
D0856_15005	COG2165	general secretion pathway protein
D0856_15010	COG1459	type II secretion system
D0856_15015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0856_15025	COG3031	protein transport across the cell outer membrane
D0856_15030	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D0856_15050	COG0456	acetyltransferase
D0856_15055	COG1490	D-aminoacyl-tRNA deacylase activity
D0856_15085	COG0174	glutamine synthetase
D0856_15095	COG3852	Histidine kinase
D0856_15100	COG2204	response regulator
D0856_15110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D0856_15115	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0856_15145	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D0856_15155	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0856_15155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0856_15175	COG0084	hydrolase, TatD family'
D0856_15180	COG0805	protein transport
D0856_15200	COG3165	ubiquinone biosynthetic process from chorismate
D0856_15210	COG1322	Protein conserved in bacteria
D0856_15230	COG2081	HI0933 family
D0856_15240	COG1528	Iron-storage protein
D0856_15245	COG0589	response to stress
D0856_15250	COG0697	spore germination
D0856_15265	COG5001	Diguanylate cyclase
D0856_15265	COG5002	protein histidine kinase activity
D0856_15270	COG1522	sequence-specific DNA binding
D0856_15285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D0856_15300	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0856_15305	COG0800	Aldolase
D0856_15310	COG2610	gluconate transmembrane transporter activity
D0856_15315	COG3265	gluconokinase activity
D0856_15320	COG0129	dihydroxy-acid dehydratase activity
D0856_15330	COG2076	Multidrug Resistance protein
D0856_15335	COG0583	DNA-binding transcription factor activity
D0856_15340	COG1609	Transcriptional regulator
D0856_15375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0856_15390	COG4172	Belongs to the ABC transporter superfamily
D0856_15440	COG1309	transcriptional regulator
D0856_15445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0856_15450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0856_15460	COG2960	long-chain fatty acid transporting porin activity
D0856_15465	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D0856_15470	COG0583	DNA-binding transcription factor activity
D0856_15520	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D0856_15545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D0856_15550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D0856_15555	COG0551	DNA topoisomerase type I activity
D0856_15565	COG0758	DNA mediated transformation
D0856_15575	COG0242	peptide deformylase activity
D0856_15585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0856_15585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0856_15590	COG0569	domain protein
D0856_15605	COG1272	protein, Hemolysin III
D0856_15610	COG4326	sporulation control protein
D0856_15620	COG3084	Protein conserved in bacteria
D0856_15630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0856_15635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0856_15640	COG0204	Acyl-transferase
D0856_15650	COG0606	chelatase, subunit chli
D0856_15660	COG3978	acetolactate synthase activity
D0856_15665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0856_15670	COG0129	dihydroxy-acid dehydratase activity
D0856_15680	COG3706	GGDEF domain
D0856_15685	COG0583	DNA-binding transcription factor activity
D0856_15690	COG2814	Major facilitator Superfamily
D0856_15695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0856_15700	COG0765	amino acid transport
D0856_15710	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D0856_15720	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D0856_15750	COG3312	ion transport
D0856_15755	COG1475	DNA binding
D0856_15760	COG1192	Involved in chromosome partitioning
D0856_15775	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0856_15805	COG1126	abc transporter atp-binding protein
D0856_15830	COG0592	DNA-directed DNA polymerase activity
D0856_15840	COG0187	DNA topoisomerase II activity
D0856_15845	COG0071	Belongs to the small heat shock protein (HSP20) family
D0856_15850	COG3977	Valine--pyruvate aminotransferase
D0856_15855	COG0366	Alpha amylase catalytic
D0856_15870	COG2119	membrane
D0856_15880	COG0425	Belongs to the sulfur carrier protein TusA family
D0856_15895	COG0604	alcohol dehydrogenase
D0856_15900	COG0183	Belongs to the thiolase family
D0856_15910	COG1739	Uncharacterized protein family UPF0029
D0856_15915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0856_15965	COG2132	Multicopper oxidase
D0856_15985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D0856_15990	COG2104	thiamine diphosphate biosynthetic process
D0856_16005	COG0006	proline dipeptidase activity
D0856_16005	COG0006	proline dipeptidase activity
D0856_16015	COG2814	Major facilitator Superfamily
D0856_16035	COG3220	belongs to the UPF0276 family
D0856_16045	COG0210	DNA helicase
D0856_16055	COG0405	Gamma-glutamyltransferase
D0856_16060	COG1280	lysine exporter protein (LysE YggA)
D0856_16070	COG2962	Rard protein
D0856_16075	COG0514	ATP-dependent DNA helicase (RecQ)
D0856_16090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D0856_16110	COG3118	belongs to the thioredoxin family
D0856_16115	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D0856_16125	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D0856_16130	COG0633	Ferredoxin
D0856_16180	COG2959	enzyme of heme biosynthesis
D0856_16185	COG1587	Uroporphyrinogen-III synthase
D0856_16195	COG3072	Adenylate cyclase
D0856_16210	COG0019	diaminopimelate decarboxylase activity
D0856_16230	COG1011	Hydrolase
D0856_16235	COG3287	FIST C domain
D0856_16235	COG2200	EAL domain
D0856_16235	COG2199	diguanylate cyclase activity
D0856_16255	COG0561	phosphatase activity
D0856_16260	COG2267	carboxylic ester hydrolase activity
D0856_16265	COG1280	lysine exporter protein (LysE YggA)
D0856_16270	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D0856_16275	COG0640	Transcriptional regulator
D0856_16280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0856_16335	COG2095	MarC family integral membrane protein
D0856_16345	COG0742	ribosomal rna small subunit methyltransferase
D0856_16350	COG0552	protein localization to endoplasmic reticulum
D0856_16355	COG2884	Cell division ATP-binding protein ftsE
D0856_16360	COG2177	Part of the ABC transporter FtsEX involved in
D0856_16375	COG0705	Rhomboid family
D0856_16380	COG1580	Controls the rotational direction of flagella during chemotaxis
D0856_16385	COG3161	chorismate lyase activity
D0856_16395	COG2937	Belongs to the GPAT DAPAT family
D0856_16415	COG0534	Mate efflux family protein
D0856_16520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0856_16575	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0856_16580	COG0250	Participates in transcription elongation, termination and antitermination
D0856_16585	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D0856_16595	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D0856_16600	COG0222	ribosome binding
D0856_16620	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
D0856_16625	COG2816	NAD+ diphosphatase activity
D0856_16635	COG1573	uracil-dna glycosylase
D0856_16645	COG3068	Protein conserved in bacteria
D0856_16650	COG1253	flavin adenine dinucleotide binding
D0856_16665	COG0151	Belongs to the GarS family
D0856_16675	COG0789	Transcriptional regulator
D0856_16680	COG3710	Transcriptional regulator
D0856_16690	COG0531	amino acid
D0856_16695	COG1982	Orn Lys Arg decarboxylase major
D0856_16740	COG5001	Diguanylate cyclase
D0856_16740	COG3300	MHYT domain
D0856_16745	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
D0856_16750	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0856_16765	COG0439	Biotin carboxylase
D0856_16770	COG0511	ligase activity, forming carbon-carbon bonds
D0856_16775	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D0856_16780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0856_16795	COG2814	Major facilitator Superfamily
D0856_16800	COG2205	protein histidine kinase activity
D0856_16800	COG2198	Histidine kinase
D0856_16800	COG0784	Response regulator, receiver
D0856_16820	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0856_16830	COG2095	MarC family integral membrane protein
D0856_16840	COG4232	protein-disulfide reductase activity
D0856_16845	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D0856_16850	COG1027	Aspartate ammonia-lyase
D0856_16855	COG3030	protein affecting phage T7 exclusion by the F plasmid
D0856_16860	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D0856_16870	COG2205	protein histidine kinase activity
D0856_16875	COG0745	RESPONSE REGULATOR receiver
D0856_16880	COG3678	ATP-independent chaperone mediated protein folding
D0856_16885	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
D0856_16895	COG0534	Mate efflux family protein
D0856_16920	COG1509	lysine 2,3-aminomutase activity
D0856_16925	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D0856_16950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D0856_16955	COG1053	succinate dehydrogenase
D0856_16980	COG4942	peptidase
D0856_16985	COG1045	serine acetyltransferase
D0856_16995	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
D0856_17000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0856_17005	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D0856_17020	COG0471	metal ion transport
D0856_17035	COG1162	GTPase activity
D0856_17040	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
D0856_17115	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D0856_17120	COG0802	atpase or kinase
D0856_17125	COG0860	N-Acetylmuramoyl-L-alanine amidase
D0856_17130	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D0856_17145	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D0856_17150	COG0330	HflC and HflK could
D0856_17155	COG0330	HflC and HflK could
D0856_17160	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
D0856_17165	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D0856_17175	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
D0856_17180	COG1017	nitric oxide dioxygenase activity
D0856_17180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0856_17190	COG0557	exoribonuclease II activity
D0856_17195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0856_17200	COG0546	phosphoglycolate phosphatase activity
D0856_17220	COG0512	Glutamine amidotransferase of anthranilate synthase
D0856_17225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D0856_17245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0856_17250	COG3954	Phosphoribulokinase
D0856_17260	COG0429	hydrolase of the alpha beta-hydrolase fold
D0856_17270	COG0488	(ABC) transporter
D0856_17280	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0856_17295	COG1047	Peptidyl-prolyl cis-trans
D0856_17305	COG1446	asparaginase
D0856_17320	COG0545	Peptidyl-prolyl cis-trans isomerase
D0856_17325	COG2964	Protein conserved in bacteria
D0856_17330	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
D0856_17335	COG2923	Belongs to the DsrF TusC family
D0856_17340	COG2168	tRNA wobble position uridine thiolation
D0856_17355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D0856_17365	COG2906	2 iron, 2 sulfur cluster binding
D0856_17375	COG0281	malic enzyme
D0856_17385	COG0626	cystathionine gamma-synthase activity
D0856_17390	COG0460	homoserine dehydrogenase
D0856_17390	COG0527	aspartate kinase activity
D0856_17395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D0856_17405	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D0856_17415	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D0856_17430	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D0856_17430	COG0165	Argininosuccinate lyase
D0856_17445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0856_17450	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D0856_17450	COG0678	peroxiredoxin activity
D0856_17460	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D0856_17505	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D0856_17515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D0856_17525	COG2965	DNA replication, synthesis of RNA primer
D0856_17545	COG0305	Participates in initiation and elongation during chromosome replication
D0856_17550	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D0856_17560	COG0432	Pfam Uncharacterised protein family UPF0047
D0856_17575	COG0735	belongs to the Fur family
D0856_17580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0856_17600	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0856_17650	COG0646	methionine synthase
D0856_17650	COG1410	methionine synthase
D0856_17655	COG0527	aspartate kinase activity
D0856_17665	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D0856_17675	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D0856_17690	COG0629	single-stranded DNA binding
D0856_17695	COG2199	diguanylate cyclase activity
D0856_17695	COG2200	EAL domain
D0856_17720	COG3409	Peptidoglycan-binding domain 1 protein
D0856_17720	COG3267	Type II secretory pathway component ExeA
D0856_17730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0856_17735	COG1459	type II secretion system
D0856_17745	COG4969	Belongs to the N-Me-Phe pilin family
D0856_17780	COG1077	Cell shape determining protein MreB Mrl
D0856_17785	COG1792	Involved in formation and maintenance of cell shape
D0856_17790	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D0856_17795	COG0424	maF-like protein
D0856_17800	COG1530	ribonuclease E activity
D0856_17805	COG3164	Protein of unknown function
D0856_17815	COG0312	modulator of DNA gyrase
D0856_17820	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D0856_17835	COG0564	pseudouridine synthase activity
D0856_17840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0856_17845	COG3028	Belongs to the UPF0307 family
D0856_17850	COG0312	modulator of DNA gyrase
D0856_17855	COG2239	Acts as a magnesium transporter
D0856_17860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0856_17870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0856_17875	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D0856_17885	COG1137	ATPase activity
D0856_17890	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
D0856_17900	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D0856_17900	COG0517	IMP dehydrogenase activity
D0856_17910	COG1127	ABC transporter
D0856_17915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D0856_17920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D0856_17925	COG2854	intermembrane phospholipid transfer
D0856_17935	COG5007	Belongs to the BolA IbaG family
D0856_17945	COG0204	Acyl-transferase
D0856_17950	COG0251	oxidation-reduction process
D0856_17990	COG0456	acetyltransferase
D0856_18000	COG0525	valine-tRNA ligase activity
D0856_18005	COG2927	DNA polymerase III (CHI subunit)
D0856_18015	COG0795	lipopolysaccharide-transporting ATPase activity
D0856_18020	COG0795	lipopolysaccharide-transporting ATPase activity
D0856_18030	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
D0856_18040	COG0726	polysaccharide deacetylase
D0856_18045	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0856_18055	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0856_18075	COG3437	response regulator, receiver
D0856_18125	COG1012	belongs to the aldehyde dehydrogenase family
D0856_18230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0856_18235	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D0856_18250	COG0762	integral membrane protein
D0856_18255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0856_18260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D0856_18275	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D0856_18280	COG1678	Uncharacterized ACR, COG1678
D0856_18285	COG0189	ligase activity
D0856_18290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D0856_18295	COG2356	endonuclease I
D0856_18310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D0856_18315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D0856_18335	COG0191	fructose-bisphosphate aldolase activity
D0856_18340	COG0668	transmembrane transport
D0856_18355	COG0583	DNA-binding transcription factor activity
D0856_18365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0856_18375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D0856_18385	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D0856_18400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0856_18405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0856_18445	COG1764	response to oxidative stress
D0856_18450	COG1846	Transcriptional regulator
D0856_18455	COG0450	alkyl hydroperoxide reductase
D0856_18460	COG3634	alkyl hydroperoxide reductase activity
D0856_18535	COG0346	lactoylglutathione lyase activity
D0856_18545	COG0583	DNA-binding transcription factor activity
D0856_18550	COG1486	melibiose metabolic process
D0856_18565	COG1522	sequence-specific DNA binding
D0856_18580	COG2258	MOSC domain
D0856_18585	COG1609	Transcriptional regulator
D0856_18590	COG1757	Na H antiporter
D0856_18595	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D0856_18600	COG0513	Belongs to the DEAD box helicase family
D0856_18620	COG1595	DNA-templated transcription, initiation
D0856_18630	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D0856_18635	COG1312	Catalyzes the dehydration of D-mannonate
D0856_18640	COG2186	Transcriptional regulator
D0856_18650	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D0856_18660	COG0246	Mannitol dehydrogenase
D0856_18665	COG1904	glucuronate isomerase
D0856_18670	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0856_18675	COG0800	Aldolase
D0856_18690	COG0549	Belongs to the carbamate kinase family
D0856_18695	COG0531	amino acid
D0856_18700	COG2957	Belongs to the agmatine deiminase family
D0856_18720	COG1132	(ABC) transporter
D0856_18745	COG0406	alpha-ribazole phosphatase activity
D0856_18800	COG2197	response regulator
D0856_18805	COG2409	Drug exporters of the RND superfamily
D0856_18870	COG4166	transmembrane transport
D0856_18885	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D0856_18890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0856_18890	COG1263	PTS System
D0856_18895	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D0856_18920	COG1444	tRNA N-acetyltransferase activity
D0856_18950	COG4608	Belongs to the ABC transporter superfamily
D0856_18955	COG0444	Belongs to the ABC transporter superfamily
D0856_18965	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0856_18965	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
D0856_18990	COG0772	Belongs to the SEDS family
D0856_19005	COG1566	PFAM secretion protein HlyD family protein
D0856_19010	COG0583	DNA-binding transcription factor activity
D0856_19040	COG3275	phosphorelay sensor kinase activity
D0856_19045	COG3279	Response regulator of the LytR AlgR family
D0856_19055	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D0856_19080	COG0786	glutamate:sodium symporter activity
D0856_19095	COG1131	(ABC) transporter
D0856_19100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0856_19105	COG0786	glutamate:sodium symporter activity
D0856_19135	COG0561	phosphatase activity
D0856_19140	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
D0856_19145	COG3623	hexulose-6-phosphate isomerase
D0856_19185	COG1741	Belongs to the pirin family
D0856_19190	COG2259	Doxx family
D0856_19200	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D0856_19205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D0856_19215	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0856_19330	COG5001	Diguanylate cyclase
D0856_19335	COG4580	involved in the transport of maltose and maltodextrins
D0856_19340	COG1609	Transcriptional regulator
D0856_19355	COG0395	ABC-type sugar transport system, permease component
D0856_19360	COG2723	6-phospho-beta-galactosidase activity
D0856_19365	COG3842	ATPase activity
D0856_19370	COG1609	Transcriptional regulator
D0856_19375	COG0534	Mate efflux family protein
D0856_19380	COG0564	pseudouridine synthase activity
D0856_19385	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D0856_19395	COG0561	phosphatase activity
D0856_19415	COG3152	Membrane
D0856_19430	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
D0856_19435	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D0856_19450	COG0583	DNA-binding transcription factor activity
D0856_19495	COG2076	Multidrug Resistance protein
D0856_19510	COG1357	PFAM Pentapeptide repeats (8 copies)
D0856_19515	COG3047	cAMP biosynthetic process
D0856_19535	COG2814	Major facilitator Superfamily
D0856_19555	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
D0856_19555	COG3408	Glycogen debranching enzyme
D0856_19585	COG0583	DNA-binding transcription factor activity
D0856_19620	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0856_19630	COG0546	phosphoglycolate phosphatase activity
D0856_19660	COG1228	amidohydrolase
D0856_19670	COG3835	regulator
D0856_19675	COG1929	Belongs to the glycerate kinase type-1 family
D0856_19680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0856_19725	COG0456	acetyltransferase
D0856_19745	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_19755	COG3005	denitrification pathway
D0856_19760	COG0243	molybdopterin cofactor binding
D0856_19765	COG5002	protein histidine kinase activity
D0856_19775	COG0671	phosphoesterase, PA-phosphatase related
D0856_19790	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D0856_19795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D0856_19800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D0856_19805	COG1116	anion transmembrane transporter activity
D0856_19810	COG0351	phosphomethylpyrimidine kinase
D0856_19815	COG0312	modulator of DNA gyrase
D0856_19820	COG0312	modulator of DNA gyrase
D0856_19885	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0856_19895	COG0584	glycerophosphoryl diester phosphodiesterase
D0856_19905	COG0745	RESPONSE REGULATOR receiver
D0856_19925	COG0811	peptide transport
D0856_19930	COG0811	peptide transport
D0856_19935	COG0848	biopolymer transport protein
D0856_19980	COG0803	Belongs to the bacterial solute-binding protein 9 family
D0856_19985	COG1121	(ABC) transporter
D0856_19990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0856_20005	COG1770	oligopeptidase
D0856_20010	COG2814	Major facilitator Superfamily
D0856_20015	COG0010	Belongs to the arginase family
D0856_20020	COG1166	arginine decarboxylase activity
D0856_20030	COG0189	ligase activity
D0856_20030	COG4067	protein conserved in archaea
D0856_20035	COG0189	ligase activity
D0856_20060	COG0583	DNA-binding transcription factor activity
D0856_20090	COG4191	Histidine kinase
D0856_20100	COG1114	Component of the transport system for branched-chain amino acids
D0856_20120	COG0579	oxidoreductase
D0856_20135	COG3033	Beta-eliminating lyase
D0856_20155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0856_20160	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0856_20195	COG3706	GGDEF domain
D0856_20200	COG0415	Belongs to the DNA photolyase family
D0856_20205	COG3046	protein related to deoxyribodipyrimidine photolyase
D0856_20220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0856_20220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0856_20225	COG1765	OsmC-like protein
D0856_20230	COG2171	N-acyltransferase activity
D0856_20260	COG3842	ATPase activity
D0856_20275	COG0439	Biotin carboxylase
D0856_20290	COG1011	Hydrolase
D0856_20325	COG3264	Mechanosensitive ion channel
D0856_20325	COG1511	domain protein
D0856_20330	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D0856_20335	COG0698	ribose 5-phosphate isomerase
D0856_20350	COG1737	Transcriptional regulator
D0856_20355	COG3240	lipase activity
D0856_20385	COG1609	Transcriptional regulator
D0856_20405	COG1840	ABC-type Fe3 transport system, periplasmic component
D0856_20415	COG3842	ATPase activity
D0856_20440	COG2990	Protein conserved in bacteria
D0856_20450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0856_20455	COG2866	Carboxypeptidase
D0856_20465	COG0583	DNA-binding transcription factor activity
D0856_20495	COG1760	l-serine dehydratase
D0856_20520	COG1388	LysM domain
D0856_20520	COG0741	lytic transglycosylase activity
D0856_20540	COG1815	bacterial-type flagellum-dependent cell motility
D0856_20545	COG1558	bacterial-type flagellum-dependent cell motility
D0856_20550	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D0856_20555	COG1749	Flagellar hook protein flgE
D0856_20560	COG4787	bacterial-type flagellum-dependent cell motility
D0856_20565	COG4786	Flagellar basal body rod
D0856_20570	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
D0856_20575	COG1706	bacterial-type flagellum-dependent cell motility
D0856_20585	COG4786	Flagellar basal body rod
D0856_20585	COG1256	bacterial-type flagellum assembly
D0856_20590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0856_20615	COG0583	DNA-binding transcription factor activity
D0856_20635	COG1253	flavin adenine dinucleotide binding
D0856_20640	COG3710	Transcriptional regulator
D0856_20655	COG2226	methyltransferase
D0856_20700	COG0384	phenazine biosynthesis protein PhzF
D0856_20710	COG1360	Flagellar Motor Protein
D0856_20715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D0856_20720	COG1191	sigma factor activity
D0856_20725	COG1580	Controls the rotational direction of flagella during chemotaxis
D0856_20740	COG1516	flagellar protein fliS
D0856_20745	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D0856_20755	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0856_20770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D0856_20780	COG1987	bacterial-type flagellum assembly
D0856_20805	COG2204	response regulator
D0856_20820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0856_20840	COG2200	EAL domain
D0856_20870	COG3188	usher protein
D0856_20975	COG4387	Mu-like prophage protein GP36
D0856_20985	COG4397	Mu-like prophage major head subunit gpT
D0856_20995	COG4388	Caudovirus prohead serine protease
D0856_21000	COG5005	Phage virion morphogenesis
D0856_21015	COG4383	Mu-like prophage protein gp29
D0856_21020	COG4373	Mu-like prophage FluMu protein gp28
D0856_21030	COG0640	Transcriptional regulator
D0856_21055	COG5566	PFAM Mor transcription activator
D0856_21075	COG4382	Mu-like prophage protein Gp16
D0856_21130	COG2842	Transposition protein
D0856_21135	COG2801	Transposase and inactivated derivatives
D0856_21145	COG3423	Transcriptional regulator
D0856_21160	COG0346	lactoylglutathione lyase activity
D0856_21185	COG0745	RESPONSE REGULATOR receiver
D0856_21210	COG0156	8-amino-7-oxononanoate synthase activity
D0856_21215	COG1063	alcohol dehydrogenase
D0856_21230	COG0668	transmembrane transport
D0856_21245	COG1304	FMN binding
D0856_21250	COG1620	l-lactate permease
D0856_21255	COG0583	DNA-binding transcription factor activity
D0856_21260	COG1505	serine-type exopeptidase activity
D0856_21265	COG4172	Belongs to the ABC transporter superfamily
D0856_21275	COG1067	ATP-dependent peptidase activity
D0856_21285	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D0856_21305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0856_21310	COG0437	4 iron, 4 sulfur cluster binding
D0856_21315	COG0348	domain, Protein
D0856_21330	COG0640	Transcriptional regulator
D0856_21340	COG2731	YhcH YjgK YiaL family protein
D0856_21355	COG1122	ATPase activity
D0856_21365	COG1566	PFAM secretion protein HlyD family protein
D0856_21380	COG3706	GGDEF domain
D0856_21395	COG0813	purine-nucleoside phosphorylase activity
D0856_21405	COG3272	Protein of unknown function (DUF1722)
D0856_21410	COG0789	Transcriptional regulator
D0856_21415	COG0415	Belongs to the DNA photolyase family
D0856_21420	COG1388	LysM domain
D0856_21420	COG1376	ErfK ybiS ycfS ynhG family protein
D0856_21430	COG0513	Belongs to the DEAD box helicase family
D0856_21435	COG1770	oligopeptidase
D0856_21440	COG4771	TonB-dependent receptor
D0856_21460	COG0840	transmembrane signaling receptor activity
D0856_21465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D0856_21470	COG0573	inorganic phosphate transmembrane transporter activity
D0856_21475	COG0581	inorganic phosphate transmembrane transporter activity
D0856_21480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0856_21515	COG0714	Associated with various cellular activities
D0856_21535	COG0840	transmembrane signaling receptor activity
D0856_21570	COG0110	maltose O-acetyltransferase activity
D0856_21575	COG2204	response regulator
D0856_21580	COG4191	Histidine kinase
D0856_21600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0856_21605	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_21620	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D0856_21620	COG2885	chlorophyll binding
D0856_21655	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0856_21660	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
D0856_21670	COG1252	NADH dehydrogenase
D0856_21675	COG1301	dicarboxylic acid transport
D0856_21685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0856_21720	COG1566	PFAM secretion protein HlyD family protein
D0856_21725	COG0583	DNA-binding transcription factor activity
D0856_21740	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0856_21740	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0856_21740	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0856_21745	COG2207	Transcriptional regulator
D0856_21755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0856_21760	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0856_21765	COG0583	DNA-binding transcription factor activity
D0856_21775	COG2084	Dehydrogenase
D0856_21780	COG0753	catalase activity
D0856_21790	COG2130	NADP-dependent
D0856_21795	COG1309	transcriptional regulator
D0856_21835	COG0438	transferase activity, transferring glycosyl groups
D0856_21845	COG0489	protein tyrosine kinase activity
D0856_21845	COG3206	protein involved in exopolysaccharide biosynthesis
D0856_21860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D0856_21865	COG3842	ATPase activity
D0856_21880	COG1175	transmembrane transport
D0856_21885	COG3833	ABC-type maltose transport systems, permease component
D0856_21915	COG2354	Protein conserved in bacteria
D0856_21925	COG0401	homolog of Blt101
D0856_21930	COG0633	Ferredoxin
D0856_21930	COG0633	Ferredoxin
D0856_21930	COG3217	Mosc domain protein beta barrel domain protein
D0856_21930	COG3217	Mosc domain protein beta barrel domain protein
D0856_21940	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D0856_21980	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
D0856_21985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0856_21995	COG0848	biopolymer transport protein
D0856_22000	COG0811	peptide transport
D0856_22015	COG3721	Heme iron utilization protein
D0856_22020	COG0748	coenzyme F420 binding
D0856_22035	COG0784	Response regulator, receiver
D0856_22035	COG0835	chemotaxis
D0856_22040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0856_22045	COG0366	Alpha amylase catalytic
D0856_22060	COG0300	oxidoreductase activity
D0856_22105	COG0583	DNA-binding transcription factor activity
D0856_22120	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0856_22125	COG0583	DNA-binding transcription factor activity
D0856_22145	COG2814	Major facilitator Superfamily
D0856_22160	COG1335	isochorismatase
D0856_22165	COG4977	sequence-specific DNA binding
D0856_22180	COG2194	sulfuric ester hydrolase activity
D0856_22185	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D0856_22195	COG2205	protein histidine kinase activity
D0856_22200	COG0745	RESPONSE REGULATOR receiver
D0856_22210	COG4221	oxidoreductase activity
D0856_22225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0856_22245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0856_22255	COG2814	Major facilitator Superfamily
D0856_22270	COG1418	mRNA catabolic process
D0856_22285	COG0402	S-adenosylhomocysteine deaminase activity
D0856_22290	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D0856_22295	COG2239	Acts as a magnesium transporter
D0856_22300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D0856_22305	COG1566	PFAM secretion protein HlyD family protein
D0856_22330	COG0745	RESPONSE REGULATOR receiver
D0856_22335	COG2205	protein histidine kinase activity
D0856_22355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0856_22365	COG0531	amino acid
D0856_22370	COG1522	sequence-specific DNA binding
D0856_22405	COG0673	inositol 2-dehydrogenase activity
D0856_22485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0856_22490	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0856_22500	COG1280	lysine exporter protein (LysE YggA)
D0856_22510	COG0183	Belongs to the thiolase family
D0856_22530	COG3005	denitrification pathway
D0856_22550	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D0856_22555	COG3850	Histidine kinase
D0856_22560	COG2197	response regulator
D0856_22575	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0856_22595	COG0840	transmembrane signaling receptor activity
D0856_22605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0856_22635	COG0545	Peptidyl-prolyl cis-trans isomerase
D0856_22665	COG1278	Cold shock
D0856_22670	COG3036	rescue of stalled ribosome
D0856_22680	COG2199	diguanylate cyclase activity
D0856_22700	COG1136	(ABC) transporter
D0856_22700	COG0577	efflux transmembrane transporter activity
D0856_22725	COG1132	(ABC) transporter
D0856_22730	COG1538	Outer membrane efflux protein
D0856_22735	COG2205	protein histidine kinase activity
D0856_22735	COG0784	Response regulator, receiver
D0856_22760	COG0840	transmembrane signaling receptor activity
D0856_22765	COG0783	Belongs to the Dps family
D0856_22775	COG1619	proteins homologs of microcin C7 resistance protein MccF
D0856_22780	COG2133	pyrroloquinoline quinone binding
D0856_22785	COG1454	alcohol dehydrogenase
D0856_22790	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
D0856_22810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0856_22815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0856_22825	COG3186	Phenylalanine-4-hydroxylase
D0856_22860	COG3530	Putative quorum-sensing-regulated virulence factor
D0856_22890	COG0523	cobalamin synthesis protein
D0856_22900	COG0513	Belongs to the DEAD box helicase family
D0856_22920	COG2200	EAL domain
D0856_22925	COG1119	ATPase activity
D0856_22940	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D0856_22955	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
D0856_22960	COG0513	Belongs to the DEAD box helicase family
D0856_22970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D0856_22985	COG3278	Belongs to the heme-copper respiratory oxidase family
D0856_23010	COG1024	Enoyl-CoA hydratase
D0856_23015	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D0856_23020	COG1960	acyl-CoA dehydrogenase activity
D0856_23030	COG0183	Belongs to the thiolase family
D0856_23045	COG1024	Enoyl-CoA hydratase
D0856_23050	COG1024	Enoyl-CoA hydratase
D0856_23060	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_23070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D0856_23075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D0856_23080	COG1845	cytochrome c oxidase, subunit III
D0856_23085	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D0856_23095	COG0446	pyridine nucleotide-disulphide oxidoreductase
D0856_23095	COG1902	pentaerythritol trinitrate reductase activity
D0856_23110	COG1012	belongs to the aldehyde dehydrogenase family
D0856_23120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0856_23185	COG1126	abc transporter atp-binding protein
D0856_23190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0856_23195	COG4215	(ABC) transporter
D0856_23200	COG4160	amino acid transport
D0856_23225	COG3119	arylsulfatase activity
D0856_23230	COG3976	FMN-binding domain protein
D0856_23230	COG1053	succinate dehydrogenase
D0856_23230	COG0431	NADPH-dependent FMN reductase
D0856_23295	COG0443	Heat shock 70 kDa protein
D0856_23300	COG2847	Copper chaperone PCu(A)C
D0856_23330	COG0745	RESPONSE REGULATOR receiver
D0856_23345	COG1785	Belongs to the alkaline phosphatase family
D0856_23370	COG3706	GGDEF domain
D0856_23380	COG0814	amino acid
D0856_23385	COG5002	protein histidine kinase activity
D0856_23385	COG5001	Diguanylate cyclase
D0856_23425	COG1116	anion transmembrane transporter activity
D0856_23425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D0856_23435	COG1116	anion transmembrane transporter activity
D0856_23440	COG2146	nitrite reductase [NAD(P)H] activity
D0856_23440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0856_23490	COG0745	RESPONSE REGULATOR receiver
D0856_23495	COG2770	Histidine kinase
D0856_23495	COG2205	protein histidine kinase activity
D0856_23500	COG4968	Prepilin-type N-terminal cleavage methylation domain
D0856_23520	COG1902	pentaerythritol trinitrate reductase activity
D0856_23530	COG1475	DNA binding
D0856_23550	COG0814	amino acid
D0856_23565	COG1414	Transcriptional regulator
D0856_23575	COG0589	response to stress
D0856_23585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D0856_23585	COG2111	Na H antiporter
D0856_23605	COG2212	antiporter activity
D0856_23610	COG1320	monovalent cation:proton antiporter activity
D0856_23615	COG1294	oxidase, subunit
D0856_23620	COG1271	oxidase subunit
D0856_23630	COG0583	DNA-binding transcription factor activity
D0856_23640	COG0739	heme binding
D0856_23675	COG0628	permease
D0856_23700	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0856_23730	COG1024	Enoyl-CoA hydratase
D0856_23745	COG0523	cobalamin synthesis protein
D0856_23755	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0856_23870	COG1132	(ABC) transporter
D0856_23930	COG4771	TonB-dependent receptor
D0856_23945	COG2205	protein histidine kinase activity
D0856_23945	COG0784	Response regulator, receiver
D0856_23950	COG3300	MHYT domain
D0856_23950	COG5001	Diguanylate cyclase
D0856_23955	COG2197	response regulator
D0856_23960	COG3706	GGDEF domain
D0856_23970	COG2197	response regulator
D0856_23980	COG0778	Nitroreductase
D0856_23985	COG0835	chemotaxis
D0856_23985	COG0784	Response regulator, receiver
D0856_24000	COG2962	Rard protein
D0856_24020	COG0671	phosphoesterase, PA-phosphatase related
D0856_24035	COG2076	Multidrug Resistance protein
D0856_24070	COG2067	long-chain fatty acid transport protein
D0856_24075	COG1234	tRNA 3'-trailer cleavage
D0856_24085	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D0856_24085	COG0069	glutamate synthase activity
D0856_24100	COG2755	lipolytic protein G-D-S-L family
D0856_24100	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
D0856_24110	COG1902	pentaerythritol trinitrate reductase activity
D0856_24115	COG0346	lactoylglutathione lyase activity
D0856_24190	COG0631	protein serine/threonine phosphatase activity
D0856_24270	COG0420	3'-5' exonuclease activity
D0856_24275	COG0419	ATPase involved in DNA repair
D0856_24285	COG3469	chitinase activity
D0856_24320	COG3040	lipid binding
D0856_24330	COG2814	Major facilitator Superfamily
D0856_24340	COG1288	antiporter activity
D0856_24350	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D0856_24365	COG2425	protein containing a von Willebrand factor type A (vWA) domain
D0856_24380	COG1472	Belongs to the glycosyl hydrolase 3 family
D0856_24385	COG0583	DNA-binding transcription factor activity
D0856_24390	COG0277	FAD linked oxidase domain protein
D0856_24465	COG2199	diguanylate cyclase activity
D0856_24475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0856_24480	COG2146	nitrite reductase [NAD(P)H] activity
D0856_24485	COG2116	formate transmembrane transporter activity
D0856_24505	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D0856_24525	COG0534	Mate efflux family protein
D0856_24535	COG2814	Major facilitator Superfamily
D0856_24540	COG3118	belongs to the thioredoxin family
D0856_24545	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0856_24575	COG1566	PFAM secretion protein HlyD family protein
D0856_24585	COG0628	permease
D0856_24595	COG1482	cell wall glycoprotein biosynthetic process
D0856_24605	COG3851	Histidine kinase
D0856_24610	COG2197	response regulator
D0856_24690	COG1328	CTP reductase activity
D0856_24695	COG0602	queuosine metabolic process
D0856_24700	COG0534	Mate efflux family protein
D0856_24725	COG3111	PFAM Bacterial OB fold (BOF) protein
D0856_24735	COG0725	ABC transporter, periplasmic molybdate-binding protein
D0856_24740	COG4149	molybdate abc transporter
D0856_24745	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D0856_24755	COG3706	GGDEF domain
D0856_24755	COG2203	Gaf domain
D0856_24755	COG5001	Diguanylate cyclase
D0856_24755	COG4251	negative regulation of phosphorylation
D0856_24765	COG0745	RESPONSE REGULATOR receiver
D0856_24765	COG3706	GGDEF domain
D0856_24790	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
D0856_24795	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
D0856_24820	COG3140	Belongs to the UPF0181 family
D0856_24885	COG0045	succinate-CoA ligase (ADP-forming) activity
D0856_24885	COG1042	CoA-binding domain protein
D0856_24885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0856_24890	COG0583	DNA-binding transcription factor activity
D0856_24905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D0856_24920	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D0856_24925	COG1984	allophanate hydrolase subunit 2
D0856_24935	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
D0856_24940	COG4181	ATPase activity
D0856_24950	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D0856_24955	COG5001	Diguanylate cyclase
D0856_24955	COG3300	MHYT domain
D0856_24965	COG0484	heat shock protein binding
D0856_25000	COG2050	protein possibly involved in aromatic compounds catabolism
D0856_25035	COG0646	methionine synthase
D0856_25035	COG1410	methionine synthase
D0856_25055	COG0737	Belongs to the 5'-nucleotidase family
D0856_25060	COG3593	DNA synthesis involved in DNA repair
D0856_25070	COG0583	DNA-binding transcription factor activity
D0856_25080	COG2116	formate transmembrane transporter activity
D0856_25090	COG3038	cytochrome b561
D0856_25105	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D0856_25110	COG0513	Belongs to the DEAD box helicase family
D0856_25115	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
D0856_25125	COG0840	transmembrane signaling receptor activity
D0856_25135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0856_25140	COG3437	response regulator, receiver
D0856_25140	COG0784	Response regulator, receiver
D0856_25155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0856_25165	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0856_25175	COG2207	Transcriptional regulator
D0856_25180	COG1979	alcohol dehydrogenase
D0856_25190	COG1126	abc transporter atp-binding protein
D0856_25195	COG0765	amino acid transport
D0856_25200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0856_25205	COG0765	amino acid transport
D0856_25210	COG2200	EAL domain
D0856_25210	COG2199	diguanylate cyclase activity
D0856_25210	COG2203	Gaf domain
D0856_25225	COG1609	Transcriptional regulator
D0856_25230	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0856_25230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0856_25235	COG1105	Belongs to the carbohydrate kinase PfkB family
D0856_25240	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
D0856_25240	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0856_25240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0856_25270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0856_25275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0856_25285	COG0404	The glycine cleavage system catalyzes the degradation of glycine
D0856_25295	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D0856_25300	COG0509	glycine decarboxylation via glycine cleavage system
D0856_25345	COG1752	Esterase of the alpha-beta hydrolase superfamily
D0856_25370	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_25380	COG2814	Major facilitator Superfamily
D0856_25590	COG1522	sequence-specific DNA binding
D0856_25625	COG0515	serine threonine protein kinase
D0856_25650	COG3501	Rhs element vgr protein
D0856_25665	COG2204	response regulator
D0856_25785	COG0739	heme binding
D0856_25790	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D0856_25820	COG3069	C4-dicarboxylate transmembrane transporter activity
D0856_25825	COG1704	LemA family
D0856_25830	COG0501	Belongs to the peptidase M48B family
D0856_25855	COG0641	radical SAM
D0856_25875	COG3111	PFAM Bacterial OB fold (BOF) protein
D0856_25880	COG1597	lipid kinase activity
D0856_25895	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D0856_25905	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D0856_25965	COG0714	Associated with various cellular activities
D0856_25970	COG0641	radical SAM
D0856_25975	COG3119	arylsulfatase activity
D0856_25980	COG0583	DNA-binding transcription factor activity
D0856_25990	COG3119	arylsulfatase activity
D0856_25995	COG3119	arylsulfatase activity
D0856_26000	COG3119	arylsulfatase activity
D0856_26030	COG2205	protein histidine kinase activity
D0856_26030	COG2198	Histidine kinase
D0856_26030	COG0784	Response regulator, receiver
D0856_26035	COG1879	ABC-type sugar transport system periplasmic component
D0856_26045	COG0210	DNA helicase
D0856_26050	COG1289	transmembrane transporter activity
D0856_26085	COG4206	TonB-dependent receptor
D0856_26095	COG0789	Transcriptional regulator
D0856_26100	COG4604	ABC transporter, ATP-binding protein
D0856_26105	COG4605	iron ion homeostasis
D0856_26110	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0856_26115	COG4607	ABC-type enterochelin transport system periplasmic component
D0856_26130	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
D0856_26145	COG1609	Transcriptional regulator
D0856_26150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0856_26155	COG1879	ABC-type sugar transport system periplasmic component
D0856_26160	COG1172	Belongs to the binding-protein-dependent transport system permease family
D0856_26165	COG1129	ABC transporter
D0856_26175	COG5001	Diguanylate cyclase
D0856_26180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D0856_26185	COG1794	racemase activity, acting on amino acids and derivatives
D0856_26190	COG1051	belongs to the nudix hydrolase family
D0856_26215	COG0586	Pfam SNARE associated Golgi protein
D0856_26285	COG0583	DNA-binding transcription factor activity
D0856_26295	COG2205	protein histidine kinase activity
D0856_26295	COG0784	Response regulator, receiver
D0856_26305	COG0784	Response regulator, receiver
D0856_26305	COG2205	protein histidine kinase activity
D0856_26345	COG0330	HflC and HflK could
D0856_26390	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
D0856_26400	COG2985	domain, Protein
D0856_26425	COG2272	Belongs to the type-B carboxylesterase lipase family
D0856_26430	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0856_26435	COG0729	surface antigen
D0856_26445	COG0598	Magnesium transport protein CorA
D0856_26450	COG0517	IMP dehydrogenase activity
D0856_26450	COG4175	Glycine betaine
D0856_26455	COG4176	ABC-type proline glycine betaine transport system permease component
D0856_26515	COG2860	membrane
D0856_26520	COG1473	amidohydrolase
D0856_26525	COG0583	DNA-binding transcription factor activity
D0856_26535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D0856_26535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D0856_26550	COG4989	oxidoreductase activity
D0856_26575	COG1914	H( )-stimulated, divalent metal cation uptake system
D0856_26595	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D0856_26615	COG2897	thiosulfate sulfurtransferase activity
D0856_26645	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D0856_26655	COG2814	Major facilitator Superfamily
D0856_26660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D0856_26675	COG1612	heme a metabolic process
D0856_26695	COG1845	cytochrome c oxidase, subunit III
D0856_26700	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
D0856_26745	COG0179	Fumarylacetoacetate (FAA) hydrolase
D0856_26760	COG0697	spore germination
D0856_26780	COG2814	Major facilitator Superfamily
D0856_26785	COG0583	DNA-binding transcription factor activity
D0856_26800	COG4774	siderophore transport
D0856_26815	COG1120	ATPase activity
D0856_26820	COG5001	Diguanylate cyclase
D0856_26825	COG0739	heme binding
D0856_26865	COG0814	amino acid
D0856_26885	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D0856_26890	COG1072	(Pantothenic acid kinase))
D0856_26900	COG1063	alcohol dehydrogenase
D0856_26905	COG2213	PTS system mannitol-specific
D0856_26910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0856_26915	COG2188	Transcriptional regulator
D0856_26920	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0856_26920	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0856_26920	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0856_26925	COG0383	alpha-mannosidase activity
D0856_26930	COG1482	cell wall glycoprotein biosynthetic process
D0856_26940	COG4989	oxidoreductase activity
D0856_26960	COG1733	regulation of RNA biosynthetic process
D0856_26975	COG0798	PFAM Bile acid sodium symporter
D0856_26990	COG1881	PFAM PEBP family protein
D0856_27000	COG0251	oxidation-reduction process
D0856_27005	COG2706	6-phosphogluconolactonase activity
D0856_27015	COG0800	Aldolase
D0856_27020	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0856_27035	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
D0856_27050	COG0840	transmembrane signaling receptor activity
D0856_27060	COG1131	(ABC) transporter
D0856_27065	COG0842	Transport permease protein
D0856_27080	COG3383	formate dehydrogenase (NAD+) activity
D0856_27100	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0856_27145	COG0456	acetyltransferase
D0856_27170	COG0714	Associated with various cellular activities
D0856_27205	COG0494	nUDIX hydrolase
D0856_27220	COG1858	cytochrome C peroxidase
D0856_27230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0856_27240	COG2067	long-chain fatty acid transport protein
D0856_27260	COG1505	serine-type exopeptidase activity
D0856_27265	COG0488	(ABC) transporter
D0856_27270	COG1720	tRNA m6t6A37 methyltransferase activity
D0856_27290	COG0589	response to stress
D0856_27315	COG1175	transmembrane transport
D0856_27320	COG0395	ABC-type sugar transport system, permease component
D0856_27325	COG3842	ATPase activity
D0856_27345	COG1846	Transcriptional regulator
D0856_27365	COG0523	cobalamin synthesis protein
D0856_27375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
D0856_27385	COG4667	esterase of the alpha-beta hydrolase superfamily
D0856_27395	COG1741	Belongs to the pirin family
D0856_27400	COG1278	Cold shock
D0856_27415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D0856_27420	COG3706	GGDEF domain
D0856_27445	COG2226	methyltransferase
D0856_27455	COG3706	GGDEF domain
D0856_27460	COG1686	Belongs to the peptidase S11 family
D0856_27465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0856_27470	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0856_27480	COG0625	glutathione transferase activity
D0856_27490	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0856_27500	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_27525	COG3746	phosphate-selective porin O and P
D0856_27540	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_27550	COG0583	DNA-binding transcription factor activity
D0856_27555	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0856_27555	COG2207	Transcriptional regulator
D0856_27560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0856_27590	COG0513	Belongs to the DEAD box helicase family
D0856_27660	COG0583	DNA-binding transcription factor activity
D0856_27680	COG1028	Short-chain dehydrogenase reductase Sdr
D0856_27685	COG2814	Major facilitator Superfamily
D0856_27695	COG1902	pentaerythritol trinitrate reductase activity
D0856_27705	COG3853	Toxic anion resistance protein (TelA)
D0856_27715	COG2255	four-way junction helicase activity
D0856_27735	COG3122	Protein conserved in bacteria
D0856_27740	COG0583	DNA-binding transcription factor activity
D0856_27745	COG0604	alcohol dehydrogenase
D0856_27760	COG0583	DNA-binding transcription factor activity
D0856_27780	COG0252	asparaginase activity
D0856_27790	COG0574	Belongs to the PEP-utilizing enzyme family
D0856_27790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D0856_27800	COG2197	response regulator
D0856_27805	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0856_27855	COG0583	DNA-binding transcription factor activity
D0856_27860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0856_27875	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D0856_27880	COG0786	glutamate:sodium symporter activity
D0856_27915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0856_27920	COG3033	Beta-eliminating lyase
D0856_27925	COG0318	PFAM AMP-dependent synthetase and ligase
D0856_27960	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0856_27970	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0856_28015	COG1621	beta-fructofuranosidase activity
D0856_28020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0856_28020	COG1263	PTS System
D0856_28025	COG2188	Transcriptional regulator
D0856_28040	COG4948	Mandelate Racemase Muconate Lactonizing
D0856_28050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D0856_28105	COG1342	Belongs to the UPF0251 family
D0856_28115	COG4176	ABC-type proline glycine betaine transport system permease component
D0856_28120	COG3448	diguanylate cyclase activity
D0856_28120	COG4175	Glycine betaine
D0856_28135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D0856_28140	COG0583	DNA-binding transcription factor activity
D0856_28190	COG1335	isochorismatase
D0856_28205	COG0753	catalase activity
D0856_28225	COG1482	cell wall glycoprotein biosynthetic process
D0856_28230	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
D0856_28235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0856_28235	COG1263	PTS System
D0856_28240	COG1609	Transcriptional regulator
D0856_28245	COG1349	DNA-binding transcription factor activity
D0856_28250	COG0346	lactoylglutathione lyase activity
D0856_28255	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0856_28255	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0856_28265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0856_28270	COG3537	Alpha-1,2-mannosidase
D0856_28275	COG3537	Alpha-1,2-mannosidase
D0856_28285	COG3537	Alpha-1,2-mannosidase
D0856_28290	COG3537	Alpha-1,2-mannosidase
D0856_28295	COG0737	Belongs to the 5'-nucleotidase family
D0856_28325	COG1280	lysine exporter protein (LysE YggA)
D0856_28330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0856_28345	COG3226	Transcriptional regulator
D0856_28360	COG0583	DNA-binding transcription factor activity
D0856_28375	COG0488	(ABC) transporter
D0856_28380	COG0435	Glutathione S-transferase
D0856_28385	COG0431	NADPH-dependent FMN reductase
D0856_28390	COG0583	DNA-binding transcription factor activity
D0856_28395	COG4628	conserved protein (DUF2132)
D0856_28400	COG0488	(ABC) transporter
D0856_28415	COG0346	lactoylglutathione lyase activity
D0856_28420	COG0384	phenazine biosynthesis protein PhzF
D0856_28435	COG3220	belongs to the UPF0276 family
D0856_28450	COG1271	oxidase subunit
D0856_28455	COG1294	oxidase, subunit
D0856_28495	COG2207	Transcriptional regulator
D0856_28520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D0856_28525	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D0856_28540	COG2205	protein histidine kinase activity
D0856_28545	COG0745	RESPONSE REGULATOR receiver
D0856_28555	COG0454	-acetyltransferase
D0856_28560	COG0148	phosphopyruvate hydratase activity
D0856_28570	COG2814	Major facilitator Superfamily
D0856_28595	COG0583	DNA-binding transcription factor activity
D0856_28605	COG3941	tape measure
D0856_28610	COG4397	Mu-like prophage major head subunit gpT
D0856_28695	COG0628	permease
D0856_28700	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
D0856_28715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0856_28725	COG4628	conserved protein (DUF2132)
D0856_28730	COG0583	DNA-binding transcription factor activity
D0856_28755	COG1686	Belongs to the peptidase S11 family
D0856_28770	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D0856_28790	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0856_28795	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0856_28820	COG0415	Belongs to the DNA photolyase family
D0856_28825	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
D0856_28835	COG4667	esterase of the alpha-beta hydrolase superfamily
D0856_28840	COG2095	MarC family integral membrane protein
D0856_28850	COG1596	polysaccharide export
D0856_28860	COG0489	protein tyrosine kinase activity
D0856_28860	COG3206	protein involved in exopolysaccharide biosynthesis
D0856_28875	COG0583	DNA-binding transcription factor activity
D0856_28880	COG2814	Major facilitator Superfamily
D0856_28910	COG1301	dicarboxylic acid transport
D0856_28915	COG3339	Conserved Protein
D0856_28920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0856_28925	COG0700	Nucleoside recognition
D0856_28930	COG3366	ferrous iron transmembrane transporter activity
D0856_28945	COG0366	Alpha amylase catalytic
D0856_28950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0856_28955	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D0856_28960	COG1640	4-alpha-glucanotransferase
D0856_28965	COG0058	SHG alpha-glucan phosphorylase activity
D0856_29070	COG1162	GTPase activity
D0856_29075	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
D0856_29115	COG4589	Belongs to the CDS family
D0856_29145	COG0531	amino acid
D0856_29150	COG1982	Orn Lys Arg decarboxylase major
D0856_29170	COG2356	endonuclease I
D0856_29205	COG2203	Gaf domain
D0856_29205	COG2199	diguanylate cyclase activity
D0856_29230	COG2221	Nitrite and sulphite reductase 4Fe-4S
D0856_29235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D0856_29250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0856_29250	COG1263	PTS System
D0856_29255	COG1760	l-serine dehydratase
D0856_29280	COG1609	Transcriptional regulator
D0856_29290	COG2814	Major facilitator Superfamily
D0856_29295	COG3214	Protein conserved in bacteria
D0856_29305	COG4771	TonB-dependent receptor
D0856_29310	COG0583	DNA-binding transcription factor activity
D0856_29315	COG4607	ABC-type enterochelin transport system periplasmic component
D0856_29320	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0856_29325	COG4605	iron ion homeostasis
D0856_29330	COG4604	ABC transporter, ATP-binding protein
D0856_29360	COG0739	heme binding
D0856_29375	COG0800	Aldolase
D0856_29380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0856_29385	COG2190	(PTS) system
D0856_29385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0856_29385	COG1263	PTS System
D0856_29395	COG2188	Transcriptional regulator
D0856_29405	COG1621	beta-fructofuranosidase activity
D0856_29420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0856_29425	COG1554	hydrolase, family 65, central catalytic
D0856_29430	COG0395	ABC-type sugar transport system, permease component
D0856_29465	COG3121	Chaperone
D0856_29470	COG3188	usher protein
D0856_29500	COG0612	Peptidase, M16
D0856_29505	COG0840	transmembrane signaling receptor activity
D0856_29550	COG0583	DNA-binding transcription factor activity
D0856_29560	COG0667	Aldo Keto reductase
D0856_29575	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0856_29585	COG0583	DNA-binding transcription factor activity
D0856_29595	COG1136	(ABC) transporter
D0856_29620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0856_29800	COG1192	Involved in chromosome partitioning
D0856_29845	COG5268	conjugation
D0856_29850	COG3451	type IV secretory pathway VirB4
D0856_29875	COG3504	Conjugal transfer protein
D0856_29910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0856_30055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0856_30145	COG1943	Transposase
D0856_30185	COG2885	chlorophyll binding
D0856_30260	COG1192	Involved in chromosome partitioning
D0856_30290	COG1396	sequence-specific DNA binding
D0856_30300	COG5268	conjugation
D0856_30305	COG3451	type IV secretory pathway VirB4
D0856_30315	COG4962	Type ii secretion system protein e
D0856_30335	COG3504	Conjugal transfer protein
D0856_30370	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB