locus-tag	class	description
GH799_00010	COG0542	response to heat
GH799_00020	COG0564	pseudouridine synthase activity
GH799_00025	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GH799_00030	COG0741	lytic transglycosylase activity
GH799_00035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GH799_00040	COG0077	Prephenate dehydratase
GH799_00040	COG1605	Chorismate mutase
GH799_00045	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
GH799_00050	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
GH799_00060	COG0488	(ABC) transporter
GH799_00075	COG0739	heme binding
GH799_00080	COG1605	Chorismate mutase
GH799_00080	COG0287	Prephenate dehydrogenase
GH799_00085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GH799_00090	COG1472	Belongs to the glycosyl hydrolase 3 family
GH799_00095	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GH799_00100	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GH799_00115	COG1966	Carbon starvation protein
GH799_00120	COG3275	phosphorelay sensor kinase activity
GH799_00125	COG3279	Response regulator of the LytR AlgR family
GH799_00130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GH799_00135	COG1047	Peptidyl-prolyl cis-trans
GH799_00140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GH799_00145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GH799_00150	COG0196	riboflavin kinase activity
GH799_00155	COG0728	peptidoglycan biosynthetic process
GH799_00160	COG0268	Binds directly to 16S ribosomal RNA
GH799_00170	COG0640	Transcriptional regulator
GH799_00180	COG0583	DNA-binding transcription factor activity
GH799_00185	COG1283	sodium-dependent phosphate transmembrane transporter activity
GH799_00195	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GH799_00200	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GH799_00205	COG0730	response to heat
GH799_00215	COG0494	nUDIX hydrolase
GH799_00225	COG3066	DNA modification
GH799_00235	COG0667	Aldo Keto reductase
GH799_00250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GH799_00260	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GH799_00265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GH799_00275	COG0716	FMN binding
GH799_00285	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GH799_00290	COG0513	Belongs to the DEAD box helicase family
GH799_00295	COG3022	response to hydroperoxide
GH799_00300	COG1115	amino acid carrier protein
GH799_00315	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GH799_00325	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GH799_00330	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
GH799_00335	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GH799_00340	COG0083	homoserine kinase activity
GH799_00355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GH799_00370	COG0745	RESPONSE REGULATOR receiver
GH799_00380	COG5002	protein histidine kinase activity
GH799_00380	COG0784	Response regulator, receiver
GH799_00380	COG2198	Histidine kinase
GH799_00385	COG4251	negative regulation of phosphorylation
GH799_00385	COG2203	Gaf domain
GH799_00385	COG3706	GGDEF domain
GH799_00385	COG5001	Diguanylate cyclase
GH799_00390	COG1242	4 iron, 4 sulfur cluster binding
GH799_00395	COG0069	glutamate synthase activity
GH799_00395	COG0067	glutamate synthase
GH799_00395	COG0070	glutamate synthase
GH799_00405	COG0067	glutamate synthase
GH799_00405	COG0069	glutamate synthase activity
GH799_00405	COG0070	glutamate synthase
GH799_00410	COG0493	'glutamate synthase
GH799_00420	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GH799_00430	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GH799_00435	COG2860	membrane
GH799_00440	COG0583	DNA-binding transcription factor activity
GH799_00445	COG0730	response to heat
GH799_00455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GH799_00460	COG0505	Belongs to the CarA family
GH799_00465	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GH799_00470	COG0494	nUDIX hydrolase
GH799_00475	COG0653	protein targeting
GH799_00485	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GH799_00490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GH799_00495	COG0849	cell division
GH799_00500	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GH799_00505	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GH799_00510	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GH799_00515	COG0772	Belongs to the SEDS family
GH799_00520	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GH799_00525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GH799_00530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GH799_00535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GH799_00540	COG0768	penicillin binding
GH799_00545	COG3116	cell division
GH799_00550	COG0275	rRNA processing
GH799_00565	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GH799_00575	COG0792	nuclease activity
GH799_00580	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GH799_00585	COG2823	Periplasmic or secreted lipoprotein
GH799_00590	COG2969	positive regulation of protein catabolic process
GH799_00595	COG0625	glutathione transferase activity
GH799_00600	COG2857	Cytochrome c1
GH799_00605	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GH799_00610	COG0723	plastoquinol--plastocyanin reductase activity
GH799_00615	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GH799_00620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GH799_00630	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GH799_00640	COG3105	Protein conserved in bacteria
GH799_00650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GH799_00655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GH799_00660	COG0187	DNA topoisomerase II activity
GH799_00665	COG3150	esterase
GH799_00675	COG3151	Protein conserved in bacteria
GH799_00680	COG0494	nUDIX hydrolase
GH799_00685	COG1538	Outer membrane efflux protein
GH799_00690	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GH799_00690	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GH799_00695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GH799_00710	COG3025	triphosphatase activity
GH799_00715	COG1392	Phosphate transport regulator
GH799_00720	COG0306	phosphate transporter
GH799_00725	COG4991	sh3 domain protein
GH799_00735	COG3267	Type II secretory pathway component ExeA
GH799_00735	COG3409	Peptidoglycan-binding domain 1 protein
GH799_00740	COG0617	tRNA 3'-terminal CCA addition
GH799_00745	COG1968	undecaprenyl-diphosphatase activity
GH799_00750	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GH799_00755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GH799_00760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
GH799_00765	COG0596	Alpha beta hydrolase
GH799_00770	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GH799_00775	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GH799_00780	COG1610	YqeY-like protein
GH799_00785	COG0358	DNA primase activity
GH799_00790	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GH799_00800	COG1464	Belongs to the NlpA lipoprotein family
GH799_00810	COG2207	Transcriptional regulator
GH799_00845	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GH799_00845	COG2213	PTS system mannitol-specific
GH799_00850	COG0246	Mannitol dehydrogenase
GH799_00855	COG3722	fumarate hydratase activity
GH799_00870	COG1461	Dihydroxyacetone kinase
GH799_00875	COG2376	Dihydroxyacetone kinase
GH799_00885	COG5002	protein histidine kinase activity
GH799_00900	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GH799_00905	COG1349	DNA-binding transcription factor activity
GH799_00915	COG0469	pyruvate kinase activity
GH799_00925	COG3706	GGDEF domain
GH799_00930	COG0440	acetolactate synthase activity
GH799_00935	COG0028	Belongs to the TPP enzyme family
GH799_00940	COG1022	Amp-dependent synthetase and ligase
GH799_00945	COG0583	DNA-binding transcription factor activity
GH799_00965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GH799_00970	COG0473	3-isopropylmalate dehydrogenase activity
GH799_00975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GH799_00980	COG0066	3-isopropylmalate dehydratase activity
GH799_00990	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GH799_00995	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
GH799_01000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GH799_01005	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GH799_01010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GH799_01015	COG2967	ApaG domain
GH799_01020	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GH799_01035	COG2966	Psort location CytoplasmicMembrane, score
GH799_01040	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GH799_01050	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GH799_01055	COG0142	geranyltranstransferase activity
GH799_01065	COG0039	L-malate dehydrogenase activity
GH799_01100	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
GH799_01105	COG1178	ABC-type Fe3 transport system permease component
GH799_01110	COG4143	(ABC) transporter
GH799_01115	COG0163	prenyltransferase activity
GH799_01120	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GH799_01130	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GH799_01135	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GH799_01145	COG2105	PFAM AIG2 family protein
GH799_01150	COG2911	Protein conserved in bacteria
GH799_01155	COG0729	surface antigen
GH799_01160	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GH799_01170	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GH799_01185	COG4181	ATPase activity
GH799_01205	COG0529	Catalyzes the synthesis of activated sulfate
GH799_01210	COG3273	potassium ion transport
GH799_01210	COG0471	metal ion transport
GH799_01220	COG2895	sulfate adenylyltransferase (ATP) activity
GH799_01225	COG0175	sulfate reduction
GH799_01230	COG1648	precorrin-2 dehydrogenase activity
GH799_01230	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GH799_01235	COG0737	Belongs to the 5'-nucleotidase family
GH799_01245	COG0513	Belongs to the DEAD box helicase family
GH799_01250	COG2153	protein acetylation
GH799_01260	COG0545	Peptidyl-prolyl cis-trans isomerase
GH799_01270	COG0203	ribosomal protein L17
GH799_01275	COG0202	RNA polymerase activity
GH799_01285	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GH799_01290	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GH799_01300	COG0201	protein transport
GH799_01305	COG0200	Binds to the 23S rRNA
GH799_01310	COG1841	ribosomal large subunit assembly
GH799_01325	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GH799_01330	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GH799_01335	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GH799_01340	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GH799_01345	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GH799_01350	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GH799_01355	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GH799_01360	COG0255	Belongs to the universal ribosomal protein uL29 family
GH799_01370	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GH799_01375	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GH799_01380	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GH799_01385	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GH799_01395	COG0088	Forms part of the polypeptide exit tunnel
GH799_01400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GH799_01410	COG0254	rRNA binding
GH799_01420	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GH799_01425	COG1609	Transcriptional regulator
GH799_01435	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GH799_01440	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GH799_01445	COG1575	Belongs to the MenA family. Type 1 subfamily
GH799_01450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GH799_01455	COG3074	FtsZ-dependent cytokinesis
GH799_01465	COG1494	fructose-1,6-bisphosphatase
GH799_01490	COG0149	triose-phosphate isomerase activity
GH799_01495	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GH799_01515	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GH799_01530	COG1482	cell wall glycoprotein biosynthetic process
GH799_01550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GH799_01555	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GH799_01560	COG0438	transferase activity, transferring glycosyl groups
GH799_01650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GH799_01660	COG1560	Kdo2-lipid A biosynthetic process
GH799_01670	COG0859	PFAM glycosyl transferase family 9
GH799_01680	COG1519	Transferase
GH799_01690	COG1028	Short-chain dehydrogenase reductase Sdr
GH799_01740	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GH799_01750	COG3642	lipopolysaccharide core region biosynthetic process
GH799_01755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GH799_01760	COG0859	PFAM glycosyl transferase family 9
GH799_01765	COG0463	Glycosyl transferase, family 2
GH799_01780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GH799_01785	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GH799_01795	COG2194	sulfuric ester hydrolase activity
GH799_01805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GH799_01810	COG2003	Belongs to the UPF0758 family
GH799_01825	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GH799_01830	COG1309	transcriptional regulator
GH799_01835	COG1560	Kdo2-lipid A biosynthetic process
GH799_01840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GH799_01845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GH799_01850	COG1561	YicC-like family, N-terminal region
GH799_01870	COG2003	Belongs to the UPF0758 family
GH799_01930	COG0328	RNA-DNA hybrid ribonuclease activity
GH799_01975	COG4608	Belongs to the ABC transporter superfamily
GH799_01980	COG0444	Belongs to the ABC transporter superfamily
GH799_01985	COG0747	negative chemotaxis
GH799_01990	COG4239	(ABC) transporter, permease
GH799_01995	COG4174	ABC transporter (Permease)
GH799_02020	COG0811	peptide transport
GH799_02025	COG0848	biopolymer transport protein
GH799_02040	COG0194	GDP metabolic process
GH799_02045	COG1758	RNA polymerase activity
GH799_02050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GH799_02055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GH799_02060	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GH799_02065	COG2233	PERMEase
GH799_02070	COG2205	protein histidine kinase activity
GH799_02075	COG0745	RESPONSE REGULATOR receiver
GH799_02085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GH799_02095	COG2183	response to ionizing radiation
GH799_02105	COG0596	Alpha beta hydrolase
GH799_02110	COG1040	competence protein
GH799_02115	COG0316	Belongs to the HesB IscA family
GH799_02115	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
GH799_02120	COG0494	nUDIX hydrolase
GH799_02125	COG1218	3'(2'),5'-bisphosphate nucleotidase
GH799_02135	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GH799_02140	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
GH799_02145	COG3156	type II secretion system protein K
GH799_02150	COG4795	General secretion pathway protein
GH799_02155	COG2165	general secretion pathway protein
GH799_02160	COG2165	general secretion pathway protein
GH799_02165	COG2165	general secretion pathway protein
GH799_02170	COG1459	type II secretion system
GH799_02175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GH799_02185	COG3031	protein transport across the cell outer membrane
GH799_02190	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GH799_02195	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GH799_02200	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GH799_02210	COG0456	acetyltransferase
GH799_02215	COG1490	D-aminoacyl-tRNA deacylase activity
GH799_02220	COG1295	ribonuclease BN
GH799_02240	COG0174	glutamine synthetase
GH799_02250	COG3852	Histidine kinase
GH799_02255	COG2204	response regulator
GH799_02265	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GH799_02270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GH799_02300	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GH799_02310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GH799_02310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GH799_02335	COG0084	hydrolase, TatD family'
GH799_02345	COG0805	protein transport
GH799_02355	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GH799_02360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GH799_02365	COG3165	ubiquinone biosynthetic process from chorismate
GH799_02370	COG2226	methyltransferase
GH799_02375	COG1322	Protein conserved in bacteria
GH799_02390	COG0628	permease
GH799_02440	COG2823	Periplasmic or secreted lipoprotein
GH799_02450	COG2081	HI0933 family
GH799_02460	COG1528	Iron-storage protein
GH799_02465	COG0589	response to stress
GH799_02470	COG0697	spore germination
GH799_02480	COG0742	ribosomal rna small subunit methyltransferase
GH799_02485	COG5001	Diguanylate cyclase
GH799_02485	COG5002	protein histidine kinase activity
GH799_02490	COG1522	sequence-specific DNA binding
GH799_02495	COG0339	signal peptide processing
GH799_02500	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GH799_02505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GH799_02510	COG0583	DNA-binding transcription factor activity
GH799_02515	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GH799_02520	COG0800	Aldolase
GH799_02525	COG2610	gluconate transmembrane transporter activity
GH799_02530	COG3265	gluconokinase activity
GH799_02535	COG0129	dihydroxy-acid dehydratase activity
GH799_02540	COG2076	Multidrug Resistance protein
GH799_02550	COG0583	DNA-binding transcription factor activity
GH799_02555	COG1609	Transcriptional regulator
GH799_02595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GH799_02605	COG0747	negative chemotaxis
GH799_02610	COG4172	Belongs to the ABC transporter superfamily
GH799_02675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GH799_02680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GH799_02690	COG2960	long-chain fatty acid transporting porin activity
GH799_02695	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GH799_02700	COG0583	DNA-binding transcription factor activity
GH799_02735	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GH799_02745	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GH799_02750	COG0408	coproporphyrinogen oxidase activity
GH799_02755	COG0009	L-threonylcarbamoyladenylate synthase
GH799_02760	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GH799_02765	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GH799_02770	COG0551	DNA topoisomerase type I activity
GH799_02775	COG2922	Belongs to the Smg family
GH799_02780	COG0758	DNA mediated transformation
GH799_02790	COG0242	peptide deformylase activity
GH799_02795	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GH799_02800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GH799_02800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GH799_02805	COG0569	domain protein
GH799_02810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GH799_02820	COG1272	protein, Hemolysin III
GH799_02825	COG4326	sporulation control protein
GH799_02835	COG3084	Protein conserved in bacteria
GH799_02845	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GH799_02850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GH799_02855	COG0204	Acyl-transferase
GH799_02865	COG0606	chelatase, subunit chli
GH799_02875	COG3978	acetolactate synthase activity
GH799_02880	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GH799_02885	COG0129	dihydroxy-acid dehydratase activity
GH799_02895	COG0583	DNA-binding transcription factor activity
GH799_02900	COG2814	Major facilitator Superfamily
GH799_02905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GH799_02910	COG0765	amino acid transport
GH799_02915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GH799_02920	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GH799_02925	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GH799_02930	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GH799_02935	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GH799_02940	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GH799_02955	COG0356	it plays a direct role in the translocation of protons across the membrane
GH799_02960	COG3312	ion transport
GH799_02965	COG1475	DNA binding
GH799_02970	COG1192	Involved in chromosome partitioning
GH799_02975	COG0357	Ribosomal RNA small subunit methyltransferase G
GH799_02980	COG0445	tRNA wobble uridine modification
GH799_02985	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GH799_03035	COG3645	SOS response
GH799_03040	COG3645	SOS response
GH799_03050	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GH799_03085	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GH799_03090	COG0706	membrane insertase activity
GH799_03095	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GH799_03100	COG0594	ribonuclease P activity
GH799_03110	COG1126	abc transporter atp-binding protein
GH799_03135	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GH799_03140	COG0592	DNA-directed DNA polymerase activity
GH799_03145	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GH799_03150	COG0187	DNA topoisomerase II activity
GH799_03170	COG0071	Belongs to the small heat shock protein (HSP20) family
GH799_03175	COG3977	Valine--pyruvate aminotransferase
GH799_03180	COG0366	Alpha amylase catalytic
GH799_03185	COG0751	glycine-tRNA ligase activity
GH799_03190	COG0752	glycyl-tRNA synthetase alpha subunit
GH799_03195	COG2119	membrane
GH799_03205	COG0425	Belongs to the sulfur carrier protein TusA family
GH799_03220	COG0604	alcohol dehydrogenase
GH799_03225	COG0183	Belongs to the thiolase family
GH799_03230	COG1024	Enoyl-CoA hydratase
GH799_03230	COG1250	3-hydroxyacyl-CoA dehydrogenase
GH799_03235	COG1739	Uncharacterized protein family UPF0029
GH799_03240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GH799_03290	COG3335	DDE superfamily endonuclease
GH799_03295	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GH799_03300	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GH799_03305	COG0352	thiamine-phosphate diphosphorylase activity
GH799_03310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GH799_03315	COG2104	thiamine diphosphate biosynthetic process
GH799_03320	COG2022	thiamine diphosphate biosynthetic process
GH799_03330	COG0006	proline dipeptidase activity
GH799_03330	COG0006	proline dipeptidase activity
GH799_03360	COG3220	belongs to the UPF0276 family
GH799_03370	COG0210	DNA helicase
GH799_03380	COG0405	Gamma-glutamyltransferase
GH799_03385	COG1280	lysine exporter protein (LysE YggA)
GH799_03395	COG2962	Rard protein
GH799_03400	COG0514	ATP-dependent DNA helicase (RecQ)
GH799_03415	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GH799_03420	COG0248	Ppx GppA phosphatase
GH799_03425	COG0513	Belongs to the DEAD box helicase family
GH799_03430	COG3118	belongs to the thioredoxin family
GH799_03435	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GH799_03450	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
GH799_03455	COG0633	Ferredoxin
GH799_03505	COG3071	HemY protein
GH799_03510	COG2959	enzyme of heme biosynthesis
GH799_03515	COG1587	Uroporphyrinogen-III synthase
GH799_03520	COG0181	hydroxymethylbilane synthase activity
GH799_03525	COG3072	Adenylate cyclase
GH799_03530	COG1965	Belongs to the frataxin family
GH799_03540	COG0019	diaminopimelate decarboxylase activity
GH799_03545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GH799_03555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GH799_03560	COG1011	Hydrolase
GH799_03565	COG3287	FIST C domain
GH799_03565	COG2199	diguanylate cyclase activity
GH799_03565	COG2200	EAL domain
GH799_03585	COG0561	phosphatase activity
GH799_03590	COG2267	carboxylic ester hydrolase activity
GH799_03595	COG1280	lysine exporter protein (LysE YggA)
GH799_03600	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GH799_03605	COG0640	Transcriptional regulator
GH799_03610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GH799_03665	COG2095	MarC family integral membrane protein
GH799_03675	COG0742	ribosomal rna small subunit methyltransferase
GH799_03680	COG0552	protein localization to endoplasmic reticulum
GH799_03685	COG2884	Cell division ATP-binding protein ftsE
GH799_03690	COG2177	Part of the ABC transporter FtsEX involved in
GH799_03700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GH799_03705	COG0705	Rhomboid family
GH799_03710	COG1580	Controls the rotational direction of flagella during chemotaxis
GH799_03715	COG3161	chorismate lyase activity
GH799_03720	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GH799_03725	COG2937	Belongs to the GPAT DAPAT family
GH799_03735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GH799_03740	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GH799_03745	COG0534	Mate efflux family protein
GH799_03750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GH799_03765	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GH799_03770	COG4206	TonB-dependent receptor
GH799_03780	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GH799_03810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GH799_03820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GH799_03855	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GH799_03865	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GH799_03870	COG0250	Participates in transcription elongation, termination and antitermination
GH799_03875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GH799_03880	COG0081	regulation of translation
GH799_03885	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GH799_03890	COG0222	ribosome binding
GH799_03895	COG0085	RNA polymerase activity
GH799_03900	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GH799_03905	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
GH799_03910	COG2816	NAD+ diphosphatase activity
GH799_03925	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GH799_03930	COG1573	uracil-dna glycosylase
GH799_03935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GH799_03940	COG3068	Protein conserved in bacteria
GH799_03945	COG1253	flavin adenine dinucleotide binding
GH799_03960	COG0151	Belongs to the GarS family
GH799_03970	COG0138	bifunctional purine biosynthesis protein purh
GH799_03980	COG0789	Transcriptional regulator
GH799_03985	COG3710	Transcriptional regulator
GH799_03995	COG0531	amino acid
GH799_04000	COG1982	Orn Lys Arg decarboxylase major
GH799_04050	COG3706	GGDEF domain
GH799_04055	COG0488	(ABC) transporter
GH799_04060	COG2814	Major facilitator Superfamily
GH799_04065	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GH799_04070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GH799_04075	COG2264	protein methyltransferase activity
GH799_04085	COG0439	Biotin carboxylase
GH799_04090	COG0511	ligase activity, forming carbon-carbon bonds
GH799_04095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GH799_04100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GH799_04115	COG2814	Major facilitator Superfamily
GH799_04120	COG2205	protein histidine kinase activity
GH799_04120	COG0784	Response regulator, receiver
GH799_04145	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GH799_04155	COG3263	regulation of cellular component size
GH799_04165	COG4232	protein-disulfide reductase activity
GH799_04170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GH799_04175	COG1027	Aspartate ammonia-lyase
GH799_04180	COG3030	protein affecting phage T7 exclusion by the F plasmid
GH799_04185	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GH799_04195	COG2205	protein histidine kinase activity
GH799_04200	COG0745	RESPONSE REGULATOR receiver
GH799_04205	COG3678	ATP-independent chaperone mediated protein folding
GH799_04215	COG0205	6-phosphofructokinase activity
GH799_04220	COG0534	Mate efflux family protein
GH799_04225	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GH799_04230	COG0459	protein refolding
GH799_04245	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GH799_04255	COG1509	lysine 2,3-aminomutase activity
GH799_04260	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GH799_04270	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GH799_04275	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
GH799_04280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GH799_04285	COG1053	succinate dehydrogenase
GH799_04295	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GH799_04315	COG4942	peptidase
GH799_04320	COG1045	serine acetyltransferase
GH799_04325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GH799_04330	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
GH799_04335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GH799_04340	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GH799_04355	COG0471	metal ion transport
GH799_04360	COG0688	phosphatidylethanolamine metabolic process
GH799_04365	COG1162	GTPase activity
GH799_04370	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GH799_04440	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GH799_04445	COG0802	atpase or kinase
GH799_04450	COG0860	N-Acetylmuramoyl-L-alanine amidase
GH799_04455	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GH799_04460	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GH799_04470	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GH799_04475	COG0330	HflC and HflK could
GH799_04480	COG0330	HflC and HflK could
GH799_04485	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
GH799_04490	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GH799_04500	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
GH799_04505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GH799_04505	COG1017	nitric oxide dioxygenase activity
GH799_04510	COG1959	2 iron, 2 sulfur cluster binding
GH799_04515	COG0557	exoribonuclease II activity
GH799_04520	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GH799_04525	COG0546	phosphoglycolate phosphatase activity
GH799_04530	COG0180	Tryptophanyl-tRNA synthetase
GH799_04560	COG0512	Glutamine amidotransferase of anthranilate synthase
GH799_04565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GH799_04575	COG1012	belongs to the aldehyde dehydrogenase family
GH799_04585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GH799_04590	COG3954	Phosphoribulokinase
GH799_04595	COG3089	Belongs to the UPF0270 family
GH799_04600	COG0429	hydrolase of the alpha beta-hydrolase fold
GH799_04610	COG0488	(ABC) transporter
GH799_04620	COG2249	NAD(P)H dehydrogenase (quinone) activity
GH799_04635	COG1047	Peptidyl-prolyl cis-trans
GH799_04645	COG1446	asparaginase
GH799_04650	COG2900	Belongs to the SlyX family
GH799_04660	COG0545	Peptidyl-prolyl cis-trans isomerase
GH799_04665	COG2964	Protein conserved in bacteria
GH799_04670	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GH799_04675	COG2923	Belongs to the DsrF TusC family
GH799_04680	COG2168	tRNA wobble position uridine thiolation
GH799_04690	COG0049	tRNA binding
GH799_04695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GH799_04700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GH799_04705	COG2906	2 iron, 2 sulfur cluster binding
GH799_04715	COG0281	malic enzyme
GH799_04725	COG0626	cystathionine gamma-synthase activity
GH799_04730	COG0460	homoserine dehydrogenase
GH799_04730	COG0527	aspartate kinase activity
GH799_04735	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GH799_04740	COG1695	Transcriptional regulator
GH799_04745	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GH799_04750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GH799_04755	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GH799_04760	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GH799_04765	COG0137	argininosuccinate synthase activity
GH799_04770	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GH799_04770	COG0165	Argininosuccinate lyase
GH799_04785	COG0678	peroxiredoxin activity
GH799_04785	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GH799_04795	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GH799_04825	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GH799_04830	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GH799_04840	COG0338	D12 class N6 adenine-specific DNA methyltransferase
GH799_04845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GH799_04850	COG0360	Binds together with S18 to 16S ribosomal RNA
GH799_04855	COG2965	DNA replication, synthesis of RNA primer
GH799_04865	COG0359	binds to the 23S rRNA
GH799_04875	COG0305	Participates in initiation and elongation during chromosome replication
GH799_04880	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GH799_04890	COG0432	Pfam Uncharacterised protein family UPF0047
GH799_04895	COG0166	Belongs to the GPI family
GH799_04905	COG0735	belongs to the Fur family
GH799_04915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GH799_04940	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GH799_04945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GH799_04950	COG0175	sulfate reduction
GH799_05025	COG0646	methionine synthase
GH799_05025	COG1410	methionine synthase
GH799_05030	COG0527	aspartate kinase activity
GH799_05035	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GH799_05045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GH799_05060	COG0629	single-stranded DNA binding
GH799_05065	COG2199	diguanylate cyclase activity
GH799_05065	COG2200	EAL domain
GH799_05090	COG3409	Peptidoglycan-binding domain 1 protein
GH799_05090	COG3267	Type II secretory pathway component ExeA
GH799_05100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GH799_05105	COG1459	type II secretion system
GH799_05150	COG1077	Cell shape determining protein MreB Mrl
GH799_05155	COG1792	Involved in formation and maintenance of cell shape
GH799_05160	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GH799_05165	COG0424	maF-like protein
GH799_05170	COG1530	ribonuclease E activity
GH799_05175	COG3164	Protein of unknown function
GH799_05180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GH799_05185	COG0312	modulator of DNA gyrase
GH799_05190	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GH799_05195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GH799_05210	COG0564	pseudouridine synthase activity
GH799_05215	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GH799_05220	COG3028	Belongs to the UPF0307 family
GH799_05225	COG0312	modulator of DNA gyrase
GH799_05230	COG2239	Acts as a magnesium transporter
GH799_05235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GH799_05240	COG1660	Displays ATPase and GTPase activities
GH799_05245	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GH799_05250	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GH799_05260	COG1137	ATPase activity
GH799_05265	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GH799_05275	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GH799_05275	COG0517	IMP dehydrogenase activity
GH799_05285	COG1127	ABC transporter
GH799_05290	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GH799_05295	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GH799_05300	COG2854	intermembrane phospholipid transfer
GH799_05310	COG5007	Belongs to the BolA IbaG family
GH799_05315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GH799_05320	COG0204	Acyl-transferase
GH799_05325	COG0251	oxidation-reduction process
GH799_05330	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
GH799_05335	COG0540	Belongs to the ATCase OTCase family
GH799_05345	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GH799_05350	COG2235	arginine
GH799_05380	COG0525	valine-tRNA ligase activity
GH799_05385	COG2927	DNA polymerase III (CHI subunit)
GH799_05390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GH799_05395	COG0795	lipopolysaccharide-transporting ATPase activity
GH799_05400	COG0795	lipopolysaccharide-transporting ATPase activity
GH799_05410	COG4325	translation initiation factor activity
GH799_05425	COG0726	polysaccharide deacetylase
GH799_05430	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GH799_05435	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
GH799_05440	COG1447	Phosphotransferase system cellobiose-specific component IIA
GH799_05445	COG1486	melibiose metabolic process
GH799_05450	COG3394	polysaccharide catabolic process
GH799_05460	COG3437	response regulator, receiver
GH799_05510	COG1012	belongs to the aldehyde dehydrogenase family
GH799_05580	COG0741	lytic transglycosylase activity
GH799_05585	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
GH799_05595	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GH799_05605	COG2066	Belongs to the glutaminase family
GH799_05610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GH799_05615	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GH799_05625	COG1872	DUF167
GH799_05630	COG0762	integral membrane protein
GH799_05635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GH799_05640	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GH799_05655	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GH799_05660	COG1678	Uncharacterized ACR, COG1678
GH799_05665	COG0189	ligase activity
GH799_05670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GH799_05675	COG2356	endonuclease I
GH799_05680	COG3091	SprT-like family
GH799_05690	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GH799_05700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GH799_05705	COG0583	DNA-binding transcription factor activity
GH799_05710	COG4771	TonB-dependent receptor
GH799_05715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GH799_05720	COG0126	phosphoglycerate kinase activity
GH799_05725	COG0191	fructose-bisphosphate aldolase activity
GH799_05730	COG0668	transmembrane transport
GH799_05735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GH799_05745	COG0583	DNA-binding transcription factor activity
GH799_05755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GH799_05760	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
GH799_05765	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GH799_05775	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GH799_05785	COG3079	Belongs to the UPF0149 family
GH799_05790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GH799_05795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GH799_05810	COG0354	folic acid binding
GH799_05815	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GH799_05825	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GH799_05835	COG1595	DNA-templated transcription, initiation
GH799_05840	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
GH799_05850	COG3086	response to oxidative stress
GH799_05855	COG0481	GTPase activity
GH799_05860	COG0681	Belongs to the peptidase S26 family
GH799_05865	COG0571	ribonuclease III activity
GH799_05870	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GH799_05875	COG1381	Involved in DNA repair and RecF pathway recombination
GH799_05880	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GH799_05885	COG0736	holo-[acyl-carrier-protein] synthase activity
GH799_05895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GH799_05905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GH799_05910	COG3956	TIGRFAM MazG family protein
GH799_05915	COG0504	CTP synthase activity
GH799_05920	COG0148	phosphopyruvate hydratase activity
GH799_05925	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GH799_05930	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GH799_05935	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GH799_05940	COG0585	pseudouridine synthase activity
GH799_05945	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GH799_05950	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GH799_05965	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GH799_05970	COG1546	Belongs to the CinA family
GH799_05975	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GH799_05980	COG2137	regulation of response to DNA damage stimulus
GH799_05985	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GH799_05990	COG0527	aspartate kinase activity
GH799_06050	COG3630	sodium ion export across plasma membrane
GH799_06055	COG0511	ligase activity, forming carbon-carbon bonds
GH799_06055	COG5016	pyruvate
GH799_06060	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
GH799_06065	COG1063	alcohol dehydrogenase
GH799_06070	COG1238	metal cluster binding
GH799_06075	COG0612	Peptidase, M16
GH799_06080	COG2918	glutathione biosynthetic process
GH799_06090	COG1854	S-ribosylhomocysteine lyase activity
GH799_06095	COG4536	flavin adenine dinucleotide binding
GH799_06100	COG4137	Cytochrome C assembly protein
GH799_06105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GH799_06110	COG0228	four-way junction DNA binding
GH799_06115	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GH799_06120	COG0336	Belongs to the RNA methyltransferase TrmD family
GH799_06125	COG0335	large ribosomal subunit rRNA binding
GH799_06130	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GH799_06135	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
GH799_06140	COG0237	dephospho-CoA kinase activity
GH799_06150	COG1459	type II secretion system
GH799_06155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GH799_06160	COG4969	Belongs to the N-Me-Phe pilin family
GH799_06165	COG0157	Belongs to the NadC ModD family
GH799_06175	COG2186	Transcriptional regulator
GH799_06180	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GH799_06185	COG0508	dehydrogenase complex catalyzes the overall conversion of
GH799_06190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GH799_06205	COG0288	reversible hydration of carbon dioxide
GH799_06210	COG0659	secondary active sulfate transmembrane transporter activity
GH799_06220	COG1131	(ABC) transporter
GH799_06225	COG0842	Transport permease protein
GH799_06230	COG1560	Kdo2-lipid A biosynthetic process
GH799_06240	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GH799_06245	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GH799_06250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GH799_06265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GH799_06275	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GH799_06280	COG1489	DNA binding
GH799_06285	COG1643	Atp-dependent helicase
GH799_06290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GH799_06295	COG1752	Esterase of the alpha-beta hydrolase superfamily
GH799_06300	COG1049	propionate catabolic process, 2-methylcitrate cycle
GH799_06305	COG3112	Uncharacterised protein family (UPF0231)
GH799_06315	COG0004	ammonium transporteR
GH799_06320	COG1840	ABC-type Fe3 transport system, periplasmic component
GH799_06330	COG3842	ATPase activity
GH799_06335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GH799_06350	COG2971	BadF BadG BcrA BcrD
GH799_06360	COG4608	Belongs to the ABC transporter superfamily
GH799_06365	COG0444	Belongs to the ABC transporter superfamily
GH799_06370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GH799_06380	COG0747	negative chemotaxis
GH799_06385	COG2205	protein histidine kinase activity
GH799_06385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GH799_06385	COG2198	Histidine kinase
GH799_06385	COG0784	Response regulator, receiver
GH799_06390	COG2813	Specifically methylates the guanine in position
GH799_06395	COG0628	permease
GH799_06400	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GH799_06405	COG0316	Belongs to the HesB IscA family
GH799_06415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GH799_06420	COG0739	heme binding
GH799_06425	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GH799_06435	COG2027	D-alanyl-D-alanine carboxypeptidase
GH799_06440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GH799_06445	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GH799_06450	COG1534	Rna-binding protein
GH799_06455	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
GH799_06460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GH799_06465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GH799_06470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GH799_06480	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GH799_06495	COG0779	Required for maturation of 30S ribosomal subunits
GH799_06500	COG0195	Participates in both transcription termination and antitermination
GH799_06505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GH799_06510	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GH799_06515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GH799_06520	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GH799_06525	COG1185	polyribonucleotide nucleotidyltransferase activity
GH799_06540	COG0534	Mate efflux family protein
GH799_06565	COG3153	acetyltransferase
GH799_06585	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GH799_06595	COG0084	hydrolase, TatD family'
GH799_06600	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GH799_06605	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GH799_06610	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
GH799_06615	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GH799_06620	COG0813	purine-nucleoside phosphorylase activity
GH799_06630	COG0560	Phosphoserine phosphatase
GH799_06640	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GH799_06645	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GH799_06650	COG0583	DNA-binding transcription factor activity
GH799_06660	COG1022	Amp-dependent synthetase and ligase
GH799_06665	COG2169	Transcriptional regulator
GH799_06690	COG4964	Belongs to the GSP D family
GH799_06750	COG0583	DNA-binding transcription factor activity
GH799_06755	COG0531	amino acid
GH799_06760	COG2731	YhcH YjgK YiaL family protein
GH799_06765	COG3250	beta-galactosidase activity
GH799_06770	COG1609	Transcriptional regulator
GH799_06780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GH799_06790	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GH799_06795	COG2017	converts alpha-aldose to the beta-anomer
GH799_06810	COG2211	Major facilitator Superfamily
GH799_06815	COG1609	Transcriptional regulator
GH799_06820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GH799_06835	COG0598	Magnesium transport protein CorA
GH799_06840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GH799_06845	COG1349	DNA-binding transcription factor activity
GH799_06850	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GH799_06855	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GH799_06870	COG2271	Major facilitator Superfamily
GH799_06875	COG0584	glycerophosphoryl diester phosphodiesterase
GH799_06880	COG2171	N-acyltransferase activity
GH799_06885	COG3141	response to X-ray
GH799_06905	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GH799_06910	COG1074	ATP-dependent DNA helicase activity
GH799_06915	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GH799_06940	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
GH799_06940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GH799_06950	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
GH799_06955	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GH799_06960	COG2166	iron-sulfur cluster assembly
GH799_06965	COG3706	GGDEF domain
GH799_06970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GH799_06975	COG0693	protein deglycase activity
GH799_06980	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GH799_07005	COG1595	DNA-templated transcription, initiation
GH799_07025	COG3056	Lipoprotein
GH799_07030	COG2813	Specifically methylates the guanine in position
GH799_07035	COG0271	Belongs to the BolA IbaG family
GH799_07040	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GH799_07045	COG1805	sodium ion transport
GH799_07050	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GH799_07055	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GH799_07060	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GH799_07065	COG2871	sodium ion transport
GH799_07070	COG1477	protein flavinylation
GH799_07085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GH799_07090	COG0514	ATP-dependent DNA helicase (RecQ)
GH799_07095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GH799_07110	COG0733	neurotransmitter:sodium symporter activity
GH799_07130	COG0442	prolyl-tRNA aminoacylation
GH799_07135	COG1720	tRNA m6t6A37 methyltransferase activity
GH799_07140	COG0254	rRNA binding
GH799_07155	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GH799_07160	COG1671	Belongs to the UPF0178 family
GH799_07185	COG3098	single-species biofilm formation
GH799_07190	COG0564	pseudouridine synthase activity
GH799_07200	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GH799_07205	COG0024	Methionine aminopeptidase
GH799_07210	COG0052	Belongs to the universal ribosomal protein uS2 family
GH799_07215	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GH799_07220	COG0528	UMP kinase activity
GH799_07225	COG0233	cytoplasmic translational termination
GH799_07230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GH799_07235	COG0575	Belongs to the CDS family
GH799_07240	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
GH799_07245	COG0750	zinc metalloprotease
GH799_07255	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
GH799_07260	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GH799_07265	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GH799_07270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GH799_07275	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GH799_07280	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GH799_07285	COG0587	DNA-directed DNA polymerase activity
GH799_07290	COG0825	malonyl-CoA metabolic process
GH799_07295	COG0037	tRNA processing
GH799_07305	COG0347	Belongs to the P(II) protein family
GH799_07310	COG3021	interspecies interaction between organisms
GH799_07320	COG0741	lytic transglycosylase activity
GH799_07320	COG1388	LysM domain
GH799_07325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GH799_07330	COG2226	methyltransferase
GH799_07335	COG0328	RNA-DNA hybrid ribonuclease activity
GH799_07340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GH799_07355	COG1960	acyl-CoA dehydrogenase activity
GH799_07360	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
GH799_07365	COG0121	glutamine amidotransferase
GH799_07370	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GH799_07375	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GH799_07380	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GH799_07385	COG2233	PERMEase
GH799_07405	COG1393	Belongs to the ArsC family
GH799_07410	COG4783	chaperone-mediated protein folding
GH799_07425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GH799_07430	COG2716	regulation of RNA biosynthetic process
GH799_07435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GH799_07455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GH799_07460	COG1393	Belongs to the ArsC family
GH799_07490	COG2837	iron assimilation
GH799_07495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GH799_07505	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GH799_07510	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GH799_07515	COG1334	flagellar protein FlaG
GH799_07520	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GH799_07530	COG1516	flagellar protein fliS
GH799_07540	COG4191	Histidine kinase
GH799_07545	COG2204	response regulator
GH799_07550	COG1677	Flagellar hook-basal body complex protein FliE
GH799_07560	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GH799_07610	COG1987	bacterial-type flagellum assembly
GH799_07635	COG0455	bacterial-type flagellum organization
GH799_07650	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
GH799_07655	COG2198	Histidine kinase
GH799_07655	COG0643	Histidine kinase
GH799_07660	COG2201	protein-glutamate methylesterase activity
GH799_07665	COG1192	Involved in chromosome partitioning
GH799_07675	COG0835	chemotaxis
GH799_07685	COG4133	protoheme IX ABC transporter activity
GH799_07690	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GH799_07695	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GH799_07700	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GH799_07705	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
GH799_07710	COG1138	Cytochrome C-type biogenesis protein
GH799_07715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GH799_07730	COG2853	Lipoprotein
GH799_07735	COG2067	long-chain fatty acid transport protein
GH799_07740	COG2067	long-chain fatty acid transport protein
GH799_07755	COG0183	Belongs to the thiolase family
GH799_07760	COG1024	Enoyl-CoA hydratase
GH799_07760	COG1250	3-hydroxyacyl-CoA dehydrogenase
GH799_07775	COG2062	phosphohistidine phosphatase, SixA
GH799_07780	COG2840	Smr protein MutS2
GH799_07785	COG2890	protein-(glutamine-N5) methyltransferase activity
GH799_07790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GH799_07795	COG2860	membrane
GH799_07805	COG3101	peptidyl-lysine hydroxylation
GH799_07820	COG0431	NADPH-dependent FMN reductase
GH799_07825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GH799_07825	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GH799_07830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GH799_07835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GH799_07840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GH799_07850	COG0101	tRNA pseudouridine synthase activity
GH799_07855	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GH799_07860	COG0285	dihydrofolate synthase activity
GH799_07865	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
GH799_07870	COG1286	toxin biosynthetic process
GH799_07875	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GH799_07880	COG0583	DNA-binding transcription factor activity
GH799_07885	COG0745	RESPONSE REGULATOR receiver
GH799_07895	COG2832	Protein of unknown function (DUF454)
GH799_07900	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GH799_07910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GH799_07915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GH799_07920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GH799_07925	COG0814	amino acid
GH799_07930	COG0251	oxidation-reduction process
GH799_07935	COG3681	Belongs to the UPF0597 family
GH799_07950	COG2261	transglycosylase associated protein
GH799_07955	COG2983	Belongs to the UPF0260 family
GH799_07960	COG0668	transmembrane transport
GH799_07965	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GH799_07970	COG0346	lactoylglutathione lyase activity
GH799_07980	COG1785	Belongs to the alkaline phosphatase family
GH799_08000	COG2226	methyltransferase
GH799_08015	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GH799_08020	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GH799_08030	COG3139	Protein of unknown function (DUF1315)
GH799_08035	COG0252	asparaginase activity
GH799_08040	COG0616	signal peptide processing
GH799_08045	COG1902	pentaerythritol trinitrate reductase activity
GH799_08045	COG0446	pyridine nucleotide-disulphide oxidoreductase
GH799_08050	COG0778	Nitroreductase
GH799_08055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GH799_08075	COG0123	including yeast histone deacetylase and acetoin utilization protein
GH799_08085	COG3083	sulfuric ester hydrolase activity
GH799_08090	COG3082	Protein of unknown function (DUF1414)
GH799_08095	COG3081	Nucleoid-associated protein
GH799_08110	COG1757	Na H antiporter
GH799_08115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GH799_08120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GH799_08125	COG2095	MarC family integral membrane protein
GH799_08130	COG1012	belongs to the aldehyde dehydrogenase family
GH799_08130	COG1454	alcohol dehydrogenase
GH799_08150	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GH799_08160	COG2056	Na+-H+ antiporter family
GH799_08165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GH799_08180	COG2885	chlorophyll binding
GH799_08190	COG0346	lactoylglutathione lyase activity
GH799_08195	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GH799_08200	COG4660	Part of a membrane complex involved in electron transport
GH799_08205	COG4659	FMN binding
GH799_08210	COG4658	electron transport chain
GH799_08215	COG4656	Part of a membrane complex involved in electron transport
GH799_08220	COG2878	Part of a membrane complex involved in electron transport
GH799_08225	COG4657	Part of a membrane complex involved in electron transport
GH799_08240	COG0556	nucleotide-excision repair
GH799_08245	COG2204	response regulator
GH799_08250	COG2198	Histidine kinase
GH799_08255	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GH799_08260	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GH799_08265	COG0521	Mo-molybdopterin cofactor biosynthetic process
GH799_08270	COG0315	cyclic pyranopterin monophosphate synthase activity
GH799_08275	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GH799_08280	COG0314	molybdopterin synthase activity
GH799_08290	COG0601	transmembrane transport
GH799_08295	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GH799_08300	COG0444	Belongs to the ABC transporter superfamily
GH799_08310	COG0435	Glutathione S-transferase
GH799_08320	COG3174	membrane
GH799_08325	COG0280	phosphate acetyltransferase
GH799_08325	COG0857	belongs to the CobB CobQ family
GH799_08330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GH799_08335	COG3092	negative regulation of chromosome organization
GH799_08345	COG4120	Belongs to the binding-protein-dependent transport system permease family
GH799_08350	COG1122	ATPase activity
GH799_08355	COG0366	Alpha amylase catalytic
GH799_08360	COG0745	RESPONSE REGULATOR receiver
GH799_08360	COG3706	GGDEF domain
GH799_08365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GH799_08370	COG0653	protein targeting
GH799_08375	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
GH799_08380	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GH799_08385	COG2186	Transcriptional regulator
GH799_08395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GH799_08395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GH799_08400	COG0489	protein tyrosine kinase activity
GH799_08405	COG0572	uridine kinase
GH799_08415	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
GH799_08420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GH799_08425	COG0659	secondary active sulfate transmembrane transporter activity
GH799_08430	COG1530	ribonuclease E activity
GH799_08435	COG0564	pseudouridine synthase activity
GH799_08440	COG0424	maF-like protein
GH799_08445	COG1399	metal-binding, possibly nucleic acid-binding protein
GH799_08455	COG0416	fatty acid biosynthetic process
GH799_08460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GH799_08490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GH799_08495	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GH799_08505	COG0084	hydrolase, TatD family'
GH799_08510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GH799_08510	COG1263	PTS System
GH799_08530	COG0733	neurotransmitter:sodium symporter activity
GH799_08545	COG4667	esterase of the alpha-beta hydrolase superfamily
GH799_08550	COG0469	pyruvate kinase activity
GH799_08555	COG1940	carbohydrate kinase activity
GH799_08560	COG0835	chemotaxis
GH799_08560	COG0784	Response regulator, receiver
GH799_08565	COG0587	DNA-directed DNA polymerase activity
GH799_08580	COG1028	Short-chain dehydrogenase reductase Sdr
GH799_08585	COG0616	signal peptide processing
GH799_08590	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GH799_08595	COG0539	negative regulation of cytoplasmic translation
GH799_08605	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
GH799_08610	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
GH799_08615	COG0284	orotidine-5'-phosphate decarboxylase activity
GH799_08620	COG4166	transmembrane transport
GH799_08635	COG0463	Glycosyl transferase, family 2
GH799_08645	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GH799_08655	COG3008	intermembrane lipid transfer
GH799_08655	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GH799_08660	COG2995	paraquat-inducible protein a
GH799_08665	COG3258	Cytochrome c
GH799_08670	COG2863	cytochrome
GH799_08710	COG4232	protein-disulfide reductase activity
GH799_08715	COG3118	belongs to the thioredoxin family
GH799_08745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GH799_08755	COG0577	efflux transmembrane transporter activity
GH799_08755	COG1136	(ABC) transporter
GH799_08760	COG1136	(ABC) transporter
GH799_08760	COG0577	efflux transmembrane transporter activity
GH799_08765	COG0577	efflux transmembrane transporter activity
GH799_08765	COG1136	(ABC) transporter
GH799_08770	COG1335	isochorismatase
GH799_08820	COG5002	protein histidine kinase activity
GH799_08820	COG3850	Histidine kinase
GH799_08825	COG0745	RESPONSE REGULATOR receiver
GH799_08835	COG0840	transmembrane signaling receptor activity
GH799_08840	COG1032	radical SAM domain protein
GH799_08845	COG5001	Diguanylate cyclase
GH799_08845	COG4251	negative regulation of phosphorylation
GH799_08845	COG3706	GGDEF domain
GH799_08845	COG2203	Gaf domain
GH799_08860	COG0583	DNA-binding transcription factor activity
GH799_08870	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GH799_08880	COG2350	Protein conserved in bacteria
GH799_08885	COG1607	acyl-coa hydrolase
GH799_08890	COG2917	probably involved in intracellular septation
GH799_08910	COG1301	dicarboxylic acid transport
GH799_08920	COG0318	PFAM AMP-dependent synthetase and ligase
GH799_08925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GH799_08930	COG0159	tryptophan synthase activity
GH799_08935	COG0133	tryptophan synthase activity
GH799_08940	COG0134	indole-3-glycerol-phosphate synthase activity
GH799_08940	COG0135	phosphoribosylanthranilate isomerase activity
GH799_08945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GH799_08950	COG0512	Glutamine amidotransferase of anthranilate synthase
GH799_08955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GH799_08965	COG0613	PHP domain protein
GH799_08970	COG0009	L-threonylcarbamoyladenylate synthase
GH799_08980	COG1187	pseudouridine synthase activity
GH799_08990	COG3099	Belongs to the UPF0263 family
GH799_08995	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GH799_09005	COG0417	DNA replication proofreading
GH799_09010	COG2197	response regulator
GH799_09015	COG0322	excinuclease ABC activity
GH799_09055	COG0019	diaminopimelate decarboxylase activity
GH799_09080	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GH799_09085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GH799_09090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GH799_09110	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
GH799_09120	COG0437	4 iron, 4 sulfur cluster binding
GH799_09125	COG3301	Polysulphide reductase, NrfD
GH799_09130	COG1138	Cytochrome C-type biogenesis protein
GH799_09140	COG4235	cytochrome complex assembly
GH799_09140	COG3088	subunit of a heme lyase
GH799_09150	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GH799_09175	COG2989	Protein conserved in bacteria
GH799_09180	COG3108	Peptidase M15
GH799_09185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GH799_09200	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
GH799_09225	COG1846	Transcriptional regulator
GH799_09230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GH799_09235	COG0840	transmembrane signaling receptor activity
GH799_09255	COG1448	Aminotransferase
GH799_09280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GH799_09290	COG0017	Asparaginyl-tRNA synthetase
GH799_09300	COG0720	synthase
GH799_09310	COG2200	EAL domain
GH799_09315	COG1760	l-serine dehydratase
GH799_09320	COG0814	amino acid
GH799_09325	COG0494	nUDIX hydrolase
GH799_09335	COG0784	Response regulator, receiver
GH799_09335	COG2205	protein histidine kinase activity
GH799_09340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GH799_09360	COG3106	COG3106 Predicted ATPase
GH799_09365	COG3768	UPF0283 membrane protein
GH799_09375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GH799_09455	COG2026	Addiction module toxin, RelE StbE family
GH799_09495	COG1051	belongs to the nudix hydrolase family
GH799_09745	COG1192	Involved in chromosome partitioning
GH799_09825	COG0456	acetyltransferase
GH799_09840	COG0346	lactoylglutathione lyase activity
GH799_10010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GH799_10010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GH799_10210	COG1757	Na H antiporter
GH799_10215	COG0174	glutamine synthetase
GH799_10225	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GH799_10230	COG1917	Cupin 2, conserved barrel domain protein
GH799_10230	COG1396	sequence-specific DNA binding
GH799_10235	COG1012	belongs to the aldehyde dehydrogenase family
GH799_10240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GH799_10250	COG2957	Belongs to the agmatine deiminase family
GH799_10255	COG1012	belongs to the aldehyde dehydrogenase family
GH799_10260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GH799_10265	COG1227	inorganic diphosphatase activity
GH799_10275	COG2200	EAL domain
GH799_10275	COG2771	luxR family
GH799_10285	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GH799_10300	COG1846	Transcriptional regulator
GH799_10305	COG2315	Protein conserved in bacteria
GH799_10325	COG0110	maltose O-acetyltransferase activity
GH799_10355	COG3063	Type IV pilus biogenesis stability protein PilW
GH799_10360	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
GH799_10375	COG0531	amino acid
GH799_10385	COG1560	Kdo2-lipid A biosynthetic process
GH799_10390	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GH799_10395	COG1280	lysine exporter protein (LysE YggA)
GH799_10405	COG1115	amino acid carrier protein
GH799_10430	COG1368	sulfuric ester hydrolase activity
GH799_10435	COG0642	Histidine kinase
GH799_10440	COG0745	RESPONSE REGULATOR receiver
GH799_10450	COG1028	Short-chain dehydrogenase reductase Sdr
GH799_10460	COG1022	Amp-dependent synthetase and ligase
GH799_10470	COG2113	Glycine betaine
GH799_10475	COG4176	ABC-type proline glycine betaine transport system permease component
GH799_10495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GH799_10500	COG0456	acetyltransferase
GH799_10505	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GH799_10510	COG0662	Cupin 2, conserved barrel domain protein
GH799_10515	COG0527	aspartate kinase activity
GH799_10520	COG1858	cytochrome C peroxidase
GH799_10535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GH799_10550	COG3290	protein histidine kinase activity
GH799_10555	COG4565	transcriptional regulatory protein
GH799_10560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GH799_10565	COG0363	glucosamine-6-phosphate deaminase activity
GH799_10570	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GH799_10590	COG3284	Transcriptional regulator
GH799_10595	COG1012	belongs to the aldehyde dehydrogenase family
GH799_10665	COG4669	(LipO)protein
GH799_10685	COG3177	Filamentation induced by cAMP protein fic
GH799_10735	COG4792	protein secretion
GH799_10740	COG4791	protein targeting
GH799_10745	COG4794	Type iii secretion
GH799_10750	COG4790	Type iii secretion
GH799_10755	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GH799_10820	COG0457	Tetratricopeptide repeat
GH799_10840	COG0730	response to heat
GH799_10870	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GH799_10875	COG0372	Belongs to the citrate synthase family
GH799_10885	COG2828	Protein conserved in bacteria
GH799_10895	COG0456	acetyltransferase
GH799_10910	COG0561	phosphatase activity
GH799_10915	COG0602	queuosine metabolic process
GH799_10920	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GH799_10925	COG3706	GGDEF domain
GH799_10965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GH799_10970	COG0840	transmembrane signaling receptor activity
GH799_10975	COG1254	Belongs to the acylphosphatase family
GH799_10980	COG2920	part of a sulfur-relay system
GH799_10990	COG0670	Belongs to the BI1 family
GH799_10995	COG1126	abc transporter atp-binding protein
GH799_11000	COG0765	amino acid transport
GH799_11005	COG4597	amino acid ABC transporter
GH799_11010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GH799_11025	COG1666	GTP binding
GH799_11030	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GH799_11050	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
GH799_11050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GH799_11055	COG3008	intermembrane lipid transfer
GH799_11060	COG2995	paraquat-inducible protein a
GH799_11065	COG1132	(ABC) transporter
GH799_11070	COG1956	GAF domain-containing protein
GH799_11075	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
GH799_11090	COG0308	aminopeptidase N
GH799_11100	COG2902	Dehydrogenase
GH799_11105	COG0167	dihydroorotate dehydrogenase activity
GH799_11120	COG0116	Belongs to the methyltransferase superfamily
GH799_11120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GH799_11145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GH799_11150	COG1067	ATP-dependent peptidase activity
GH799_11155	COG3120	sequence-specific DNA binding
GH799_11275	COG3278	Belongs to the heme-copper respiratory oxidase family
GH799_11290	COG2010	Cytochrome c
GH799_11300	COG2217	Heavy metal translocating P-type atpase
GH799_11315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GH799_11320	COG0589	response to stress
GH799_11330	COG0037	tRNA processing
GH799_11350	COG3842	ATPase activity
GH799_11355	COG1176	ABC-type spermidine putrescine transport system, permease component I
GH799_11360	COG1177	transmembrane transport
GH799_11365	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GH799_11370	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GH799_11375	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GH799_11385	COG0004	ammonium transporteR
GH799_11425	COG0437	4 iron, 4 sulfur cluster binding
GH799_11430	COG0243	molybdopterin cofactor binding
GH799_11430	COG3383	formate dehydrogenase (NAD+) activity
GH799_11440	COG3381	protein complex oligomerization
GH799_11465	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GH799_11470	COG0488	(ABC) transporter
GH799_11480	COG4191	Histidine kinase
GH799_11485	COG2204	response regulator
GH799_11505	COG3842	ATPase activity
GH799_11510	COG0746	molybdenum cofactor guanylyltransferase activity
GH799_11515	COG0303	'Molybdopterin
GH799_11525	COG1940	carbohydrate kinase activity
GH799_11565	COG3290	protein histidine kinase activity
GH799_11565	COG0840	transmembrane signaling receptor activity
GH799_11570	COG0791	NLP P60 protein
GH799_11580	COG3706	GGDEF domain
GH799_11585	COG2201	protein-glutamate methylesterase activity
GH799_11600	COG0307	riboflavin synthase, alpha
GH799_11605	COG0534	Mate efflux family protein
GH799_11615	COG1793	dna ligase
GH799_11650	COG2204	response regulator
GH799_11660	COG0438	transferase activity, transferring glycosyl groups
GH799_11695	COG0438	transferase activity, transferring glycosyl groups
GH799_11700	COG1215	transferase activity, transferring glycosyl groups
GH799_11705	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GH799_11715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GH799_11730	COG1643	Atp-dependent helicase
GH799_11735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GH799_11750	COG3302	dmso reductase anchor subunit
GH799_11755	COG0437	4 iron, 4 sulfur cluster binding
GH799_11760	COG0243	molybdopterin cofactor binding
GH799_11800	COG0443	Heat shock 70 kDa protein
GH799_11805	COG0443	Heat shock 70 kDa protein
GH799_11835	COG1132	(ABC) transporter
GH799_11840	COG1132	(ABC) transporter
GH799_11865	COG0814	amino acid
GH799_11880	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
GH799_11950	COG1522	sequence-specific DNA binding
GH799_11985	COG0515	serine threonine protein kinase
GH799_12010	COG3501	Rhs element vgr protein
GH799_12030	COG2885	chlorophyll binding
GH799_12050	COG0739	heme binding
GH799_12060	COG0861	Integral membrane protein TerC family
GH799_12070	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GH799_12075	COG1328	CTP reductase activity
GH799_12080	COG1280	lysine exporter protein (LysE YggA)
GH799_12090	COG5001	Diguanylate cyclase
GH799_12090	COG3300	MHYT domain
GH799_12100	COG4191	Histidine kinase
GH799_12100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GH799_12105	COG0471	metal ion transport
GH799_12140	COG0583	DNA-binding transcription factor activity
GH799_12145	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GH799_12375	COG1783	phage Terminase large subunit
GH799_12420	COG0557	exoribonuclease II activity
GH799_12425	COG1278	Cold shock
GH799_12535	COG0625	glutathione transferase activity
GH799_12545	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GH799_12555	COG2195	Cleaves the N-terminal amino acid of tripeptides
GH799_12565	COG0601	transmembrane transport
GH799_12570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GH799_12575	COG0444	Belongs to the ABC transporter superfamily
GH799_12595	COG3291	Pkd domain containing protein
GH799_12605	COG1177	transmembrane transport
GH799_12610	COG1176	ABC-type spermidine putrescine transport system, permease component I
GH799_12620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GH799_12625	COG2423	ornithine cyclodeaminase activity
GH799_12645	COG3938	Belongs to the proline racemase family
GH799_12675	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GH799_12680	COG1451	nucleotide metabolic process
GH799_12685	COG3475	LICD family
GH799_12690	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GH799_12695	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
GH799_12715	COG0583	DNA-binding transcription factor activity
GH799_12735	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
GH799_12740	COG4139	cobalamin transport
GH799_12745	COG2988	succinylglutamate desuccinylase activity
GH799_12770	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GH799_12775	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GH799_12780	COG0702	epimerase
GH799_12790	COG2925	Exonuclease
GH799_12795	COG1380	Effector of murein hydrolase LrgA
GH799_12800	COG1346	cytolysis
GH799_12805	COG0295	cytidine deaminase activity
GH799_12810	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GH799_12815	COG0500	methyltransferase
GH799_12825	COG0776	regulation of translation
GH799_12840	COG0072	phenylalanine-tRNA ligase activity
GH799_12840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GH799_12845	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GH799_12850	COG3706	GGDEF domain
GH799_12880	COG0393	Putative heavy-metal-binding
GH799_12890	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GH799_12900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GH799_12915	COG2188	Transcriptional regulator
GH799_12920	COG1228	amidohydrolase
GH799_12925	COG0010	Belongs to the arginase family
GH799_12930	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GH799_12935	COG2986	histidine ammonia-lyase
GH799_12950	COG0277	FAD linked oxidase domain protein
GH799_12950	COG0247	lactate metabolic process
GH799_12985	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GH799_13000	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
GH799_13005	COG1643	Atp-dependent helicase
GH799_13010	COG0281	malic enzyme
GH799_13015	COG2949	membrane
GH799_13020	COG0471	metal ion transport
GH799_13025	COG0745	RESPONSE REGULATOR receiver
GH799_13025	COG3706	GGDEF domain
GH799_13045	COG0492	ferredoxin-NADP+ reductase activity
GH799_13050	COG4988	ABC transporter
GH799_13055	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GH799_13060	COG3048	D-serine ammonia-lyase activity
GH799_13065	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GH799_13075	COG4191	Histidine kinase
GH799_13075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GH799_13090	COG3070	regulator of competence-specific genes
GH799_13105	COG2431	L-lysine efflux transmembrane transporter activity
GH799_13115	COG0076	glutamate decarboxylase activity
GH799_13120	COG1737	Transcriptional regulator
GH799_13135	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GH799_13140	COG3273	potassium ion transport
GH799_13140	COG2985	domain, Protein
GH799_13145	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GH799_13160	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GH799_13175	COG4181	ATPase activity
GH799_13180	COG0534	Mate efflux family protein
GH799_13185	COG0702	epimerase
GH799_13190	COG3005	denitrification pathway
GH799_13220	COG2814	Major facilitator Superfamily
GH799_13225	COG1187	pseudouridine synthase activity
GH799_13230	COG1061	Type III restriction enzyme res subunit
GH799_13240	COG0745	RESPONSE REGULATOR receiver
GH799_13245	COG2205	protein histidine kinase activity
GH799_13250	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GH799_13280	COG3313	Fe-S protein
GH799_13305	COG0493	'glutamate synthase
GH799_13315	COG0398	Pfam SNARE associated Golgi protein
GH799_13320	COG4134	Bacterial extracellular solute-binding protein
GH799_13325	COG4135	transport system, permease component
GH799_13330	COG4136	ATPase activity
GH799_13335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GH799_13350	COG3604	Transcriptional regulator
GH799_13355	COG1151	hydroxylamine reductase activity
GH799_13360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GH799_13370	COG0564	pseudouridine synthase activity
GH799_13380	COG0733	neurotransmitter:sodium symporter activity
GH799_13390	COG0626	cystathionine gamma-synthase activity
GH799_13395	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
GH799_13400	COG5380	lipid catabolic process
GH799_13405	COG2818	Glycosylase
GH799_13420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GH799_13425	COG1983	PspC domain protein
GH799_13435	COG1842	Phage shock protein A
GH799_13440	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
GH799_13450	COG4168	peptide transport system, permease
GH799_13455	COG4171	peptide transport system, permease
GH799_13465	COG4172	Belongs to the ABC transporter superfamily
GH799_13475	COG1227	inorganic diphosphatase activity
GH799_13490	COG0243	molybdopterin cofactor binding
GH799_13495	COG3005	denitrification pathway
GH799_13500	COG4459	periplasmic nitrate reductase
GH799_13505	COG0390	transport system, permease component
GH799_13515	COG2116	formate transmembrane transporter activity
GH799_13540	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GH799_13545	COG1435	thymidine kinase activity
GH799_13550	COG0215	cysteine-tRNA ligase activity
GH799_13555	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GH799_13560	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GH799_13565	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
GH799_13575	COG3012	SEC-C Motif Domain Protein
GH799_13580	COG0140	phosphoribosyl-ATP diphosphatase activity
GH799_13580	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GH799_13585	COG0107	imidazoleglycerol-phosphate synthase activity
GH799_13590	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GH799_13595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GH799_13600	COG0131	Imidazoleglycerol-phosphate dehydratase
GH799_13600	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GH799_13605	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GH799_13610	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GH799_13615	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GH799_13630	COG1757	Na H antiporter
GH799_13640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GH799_13650	COG0482	sulfurtransferase activity
GH799_13655	COG2915	High frequency lysogenization protein hflD homolog
GH799_13660	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GH799_13685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GH799_13700	COG0300	oxidoreductase activity
GH799_13710	COG0501	Belongs to the peptidase M48B family
GH799_13720	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GH799_13730	COG0156	8-amino-7-oxononanoate synthase activity
GH799_13735	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GH799_13740	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GH799_13745	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GH799_13755	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GH799_13760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GH799_13765	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GH799_13770	COG1674	ftsk spoiiie
GH799_13780	COG0686	Belongs to the AlaDH PNT family
GH799_13790	COG0583	DNA-binding transcription factor activity
GH799_13805	COG3568	Endonuclease Exonuclease Phosphatase
GH799_13835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GH799_13855	COG0840	transmembrane signaling receptor activity
GH799_13880	COG0328	RNA-DNA hybrid ribonuclease activity
GH799_13910	COG5002	protein histidine kinase activity
GH799_13910	COG0784	Response regulator, receiver
GH799_13920	COG0754	glutathionylspermidine amidase activity
GH799_13930	COG3766	membrane
GH799_13940	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GH799_13945	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
GH799_13950	COG2885	chlorophyll binding
GH799_13955	COG0823	Involved in the tonB-independent uptake of proteins
GH799_13970	COG0811	peptide transport
GH799_13975	COG0824	Thioesterase
GH799_13985	COG4890	Cyd operon protein YbgT
GH799_13990	COG1294	oxidase, subunit
GH799_13995	COG1271	oxidase subunit
GH799_14000	COG2255	four-way junction helicase activity
GH799_14005	COG0632	four-way junction helicase activity
GH799_14010	COG0840	transmembrane signaling receptor activity
GH799_14015	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GH799_14020	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GH799_14025	COG1801	Protein of unknown function DUF72
GH799_14030	COG4106	trans-aconitate 2-methyltransferase activity
GH799_14035	COG0500	methyltransferase
GH799_14045	COG0189	ligase activity
GH799_14045	COG4067	protein conserved in archaea
GH799_14065	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GH799_14070	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
GH799_14075	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
GH799_14080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GH799_14085	COG1434	Gram-negative-bacterium-type cell wall biogenesis
GH799_14090	COG0745	RESPONSE REGULATOR receiver
GH799_14095	COG3381	protein complex oligomerization
GH799_14100	COG1609	Transcriptional regulator
GH799_14105	COG3070	regulator of competence-specific genes
GH799_14125	COG0297	glycogen (starch) synthase activity
GH799_14130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GH799_14135	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GH799_14145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GH799_14155	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GH799_14160	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
GH799_14165	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GH799_14175	COG0542	response to heat
GH799_14180	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GH799_14185	COG1278	Cold shock
GH799_14195	COG1187	pseudouridine synthase activity
GH799_14200	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GH799_14210	COG1199	ATP-dependent helicase activity
GH799_14215	COG0730	response to heat
GH799_14220	COG3923	Primosomal replication protein n
GH799_14230	COG0708	Exodeoxyribonuclease III
GH799_14245	COG4215	(ABC) transporter
GH799_14275	COG1882	Formate acetyltransferase
GH799_14285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GH799_14295	COG3013	Belongs to the UPF0304 family
GH799_14305	COG2766	serine protein kinase
GH799_14310	COG2718	Belongs to the UPF0229 family
GH799_14315	COG2719	SpoVR family
GH799_14320	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GH799_14330	COG1663	tetraacyldisaccharide 4'-kinase activity
GH799_14335	COG1132	(ABC) transporter
GH799_14340	COG2333	competence protein COMEC
GH799_14340	COG0658	competence protein
GH799_14350	COG4591	ABC-type transport system involved in lipoprotein release permease component
GH799_14355	COG1136	(ABC) transporter
GH799_14360	COG4591	ABC-type transport system involved in lipoprotein release permease component
GH799_14370	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GH799_14385	COG1252	NADH dehydrogenase
GH799_14395	COG3150	esterase
GH799_14420	COG0537	adenosine 5'-monophosphoramidase activity
GH799_14450	COG0517	IMP dehydrogenase activity
GH799_14450	COG0516	GMP reductase activity
GH799_14460	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GH799_14465	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GH799_14470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GH799_14480	COG2199	diguanylate cyclase activity
GH799_14495	COG3126	Type III secretion system lipoprotein chaperone (YscW)
GH799_14500	COG1946	Acyl-CoA thioesterase
GH799_14510	COG1522	sequence-specific DNA binding
GH799_14540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GH799_14545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GH799_14590	COG0477	Major facilitator Superfamily
GH799_14595	COG2855	membrane
GH799_14615	COG1441	menaquinone biosynthetic process
GH799_14620	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GH799_14625	COG0596	Alpha beta hydrolase
GH799_14630	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GH799_14635	COG1169	isochorismate synthase
GH799_14640	COG0436	Aminotransferase
GH799_14645	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
GH799_14650	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GH799_14665	COG1555	photosystem II stabilization
GH799_14670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GH799_14675	COG0776	regulation of translation
GH799_14680	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GH799_14685	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GH799_14695	COG0544	peptidyl-prolyl cis-trans isomerase activity
GH799_14705	COG2204	response regulator
GH799_14715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
GH799_14720	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GH799_14725	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
GH799_14730	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GH799_14750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GH799_14755	COG0569	domain protein
GH799_14760	COG0513	Belongs to the DEAD box helicase family
GH799_14765	COG1253	flavin adenine dinucleotide binding
GH799_14795	COG0204	Acyl-transferase
GH799_14795	COG0318	PFAM AMP-dependent synthetase and ligase
GH799_14800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GH799_14805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GH799_14820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GH799_14825	COG1216	Glycosyl transferase, family 2
GH799_14830	COG2986	histidine ammonia-lyase
GH799_14855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GH799_14860	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GH799_14865	COG1028	Short-chain dehydrogenase reductase Sdr
GH799_14870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GH799_14885	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GH799_14890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GH799_14895	COG0583	DNA-binding transcription factor activity
GH799_14900	COG2951	lytic endotransglycosylase activity
GH799_14905	COG3100	YcgL domain-containing protein
GH799_14910	COG0850	regulation of cytokinetic process
GH799_14915	COG2894	cell division
GH799_14920	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
GH799_14925	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
GH799_14930	COG0318	PFAM AMP-dependent synthetase and ligase
GH799_14935	COG2267	carboxylic ester hydrolase activity
GH799_14950	COG1214	PFAM Peptidase M22, glycoprotease
GH799_14955	COG1199	ATP-dependent helicase activity
GH799_14960	COG0788	formyltetrahydrofolate deformylase activity
GH799_14965	COG3102	Protein conserved in bacteria
GH799_14975	COG0018	arginyl-trna synthetase
GH799_14995	COG1918	ferrous iron import across plasma membrane
GH799_15010	COG4977	sequence-specific DNA binding
GH799_15015	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
GH799_15020	COG1121	(ABC) transporter
GH799_15025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GH799_15035	COG0045	succinate-CoA ligase (ADP-forming) activity
GH799_15040	COG0508	dehydrogenase complex catalyzes the overall conversion of
GH799_15045	COG0567	Dehydrogenase, E1 component
GH799_15050	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GH799_15055	COG1053	succinate dehydrogenase
GH799_15060	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GH799_15065	COG2009	succinate dehydrogenase
GH799_15075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GH799_15085	COG0033	Phosphoglucomutase
GH799_15090	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
GH799_15095	COG0596	Alpha beta hydrolase
GH799_15105	COG0716	FMN binding
GH799_15115	COG0735	belongs to the Fur family
GH799_15120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GH799_15125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GH799_15125	COG2190	(PTS) system
GH799_15125	COG1263	PTS System
GH799_15135	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
GH799_15140	COG1846	Transcriptional regulator
GH799_15140	COG1940	carbohydrate kinase activity
GH799_15145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GH799_15145	COG4651	solute:proton antiporter activity
GH799_15150	COG0367	asparagine synthase
GH799_15155	COG0250	Participates in transcription elongation, termination and antitermination
GH799_15160	COG3104	oligopeptide transport
GH799_15165	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GH799_15170	COG0563	adenylate kinase activity
GH799_15175	COG0326	Molecular chaperone. Has ATPase activity
GH799_15180	COG3710	Transcriptional regulator
GH799_15200	COG0622	Phosphoesterase
GH799_15230	COG1090	epimerase
GH799_15235	COG0300	oxidoreductase activity
GH799_15245	COG3118	belongs to the thioredoxin family
GH799_15250	COG0330	HflC and HflK could
GH799_15275	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GH799_15280	COG3115	cell septum assembly
GH799_15285	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
GH799_15290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GH799_15300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GH799_15305	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GH799_15310	COG2190	(PTS) system
GH799_15320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GH799_15325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GH799_15335	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GH799_15345	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GH799_15355	COG3951	Flagellar rod assembly protein muramidase FlgJ
GH799_15355	COG1705	Flagellar rod assembly protein muramidase FlgJ
GH799_15360	COG1706	bacterial-type flagellum-dependent cell motility
GH799_15365	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GH799_15370	COG4786	Flagellar basal body rod
GH799_15375	COG4787	bacterial-type flagellum-dependent cell motility
GH799_15385	COG1749	Flagellar hook protein flgE
GH799_15390	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GH799_15395	COG1558	bacterial-type flagellum-dependent cell motility
GH799_15400	COG1815	bacterial-type flagellum-dependent cell motility
GH799_15405	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
GH799_15410	COG0784	Response regulator, receiver
GH799_15410	COG0835	chemotaxis
GH799_15470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GH799_15475	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GH799_15490	COG2217	Heavy metal translocating P-type atpase
GH799_15490	COG2608	mercury ion transmembrane transporter activity
GH799_15530	COG2840	Smr protein MutS2
GH799_15535	COG1187	pseudouridine synthase activity
GH799_15545	COG0737	Belongs to the 5'-nucleotidase family
GH799_15550	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GH799_15555	COG2912	Transglutaminase-like superfamily
GH799_15560	COG3094	Invasion gene expression up-regulator, SirB
GH799_15565	COG2890	protein-(glutamine-N5) methyltransferase activity
GH799_15570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GH799_15575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GH799_15590	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GH799_15595	COG0193	aminoacyl-tRNA hydrolase activity
GH799_15600	COG0012	GTP binding
GH799_15705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GH799_15715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GH799_15720	COG1702	phosphate starvation-inducible protein PhoH
GH799_15725	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GH799_15730	COG4535	Mg2 and Co2 transporter CorC
GH799_15735	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GH799_15740	COG2888	peptidyl-tyrosine sulfation
GH799_15745	COG0495	leucyl-tRNA aminoacylation
GH799_15750	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
GH799_15755	COG1466	dna polymerase III delta subunit
GH799_15760	COG0799	negative regulation of ribosome biogenesis
GH799_15765	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GH799_15770	COG0768	penicillin binding
GH799_15775	COG0772	Belongs to the SEDS family
GH799_15780	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GH799_15785	COG1686	Belongs to the peptidase S11 family
GH799_15790	COG2921	Belongs to the UPF0250 family
GH799_15795	COG0321	lipoyl(octanoyl) transferase activity
GH799_15800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GH799_15805	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GH799_15810	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GH799_15825	COG0366	Alpha amylase catalytic
GH799_15830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GH799_15830	COG1263	PTS System
GH799_15840	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
GH799_15850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GH799_15855	COG2011	ABC-type metal ion transport system permease component
GH799_15860	COG1464	Belongs to the NlpA lipoprotein family
GH799_15865	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
GH799_15875	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GH799_15875	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GH799_15885	COG0745	RESPONSE REGULATOR receiver
GH799_15885	COG3706	GGDEF domain
GH799_15890	COG1611	Belongs to the LOG family
GH799_15895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GH799_15905	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
GH799_15910	COG2363	Small membrane protein
GH799_15925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GH799_15925	COG0301	tRNA thio-modification
GH799_15930	COG2885	chlorophyll binding
GH799_15935	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GH799_15940	COG1722	exodeoxyribonuclease VII activity
GH799_15945	COG0142	geranyltranstransferase activity
GH799_15950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GH799_15955	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GH799_15960	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GH799_15965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GH799_15985	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GH799_15985	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GH799_15990	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GH799_15995	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GH799_16000	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GH799_16015	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
GH799_16020	COG2252	PERMEase
GH799_16025	COG2195	Cleaves the N-terminal amino acid of tripeptides
GH799_16050	COG0047	phosphoribosylformylglycinamidine synthase activity
GH799_16050	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GH799_16060	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
GH799_16070	COG0590	tRNA wobble adenosine to inosine editing
GH799_16075	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
GH799_16100	COG4969	Belongs to the N-Me-Phe pilin family
GH799_16115	COG0484	heat shock protein binding
GH799_16120	COG0443	Heat shock 70 kDa protein
GH799_16125	COG1301	dicarboxylic acid transport
GH799_16130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GH799_16135	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GH799_16145	COG0497	DNA recombination
GH799_16150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GH799_16155	COG2914	Belongs to the UPF0125 (RnfH) family
GH799_16160	COG2867	negative regulation of translational initiation
GH799_16165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GH799_16185	COG0583	DNA-binding transcription factor activity
GH799_16190	COG3153	acetyltransferase
GH799_16190	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GH799_16210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GH799_16215	COG2873	o-acetylhomoserine
GH799_16250	COG1115	amino acid carrier protein
GH799_16260	COG1584	GPR1 FUN34 yaaH family protein
GH799_16270	COG1757	Na H antiporter
GH799_16275	COG0519	Catalyzes the synthesis of GMP from XMP
GH799_16275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GH799_16280	COG0517	IMP dehydrogenase activity
GH799_16280	COG0516	GMP reductase activity
GH799_16285	COG1570	exodeoxyribonuclease VII activity
GH799_16300	COG1160	GTP binding
GH799_16305	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GH799_16310	COG2976	Protein conserved in bacteria
GH799_16315	COG0124	histidyl-tRNA synthetase
GH799_16320	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GH799_16335	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GH799_16340	COG0105	UTP biosynthetic process
GH799_16345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GH799_16350	COG2975	iron-sulfur cluster assembly
GH799_16355	COG0633	Ferredoxin
GH799_16360	COG0443	Heat shock 70 kDa protein
GH799_16365	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
GH799_16375	COG0822	iron-sulfur transferase activity
GH799_16380	COG1104	cysteine desulfurase activity
GH799_16385	COG1959	2 iron, 2 sulfur cluster binding
GH799_16395	COG0483	inositol monophosphate 1-phosphatase activity
GH799_16405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GH799_16410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GH799_16415	COG1862	Preprotein translocase
GH799_16420	COG0343	queuine tRNA-ribosyltransferase activity
GH799_16425	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GH799_16435	COG0517	IMP dehydrogenase activity
GH799_16445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GH799_16455	COG0583	DNA-binding transcription factor activity
GH799_16460	COG0450	alkyl hydroperoxide reductase
GH799_16465	COG3142	Participates in the control of copper homeostasis
GH799_16475	COG0704	Plays a role in the regulation of phosphate uptake
GH799_16480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GH799_16485	COG0581	inorganic phosphate transmembrane transporter activity
GH799_16495	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GH799_16500	COG0248	Ppx GppA phosphatase
GH799_16510	COG5002	protein histidine kinase activity
GH799_16515	COG0745	RESPONSE REGULATOR receiver
GH799_16520	COG2974	May be involved in recombination
GH799_16530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GH799_16575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GH799_16580	COG0581	inorganic phosphate transmembrane transporter activity
GH799_16585	COG0573	inorganic phosphate transmembrane transporter activity
GH799_16590	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GH799_16615	COG4771	TonB-dependent receptor
GH799_16620	COG1770	oligopeptidase
GH799_16625	COG0513	Belongs to the DEAD box helicase family
GH799_16635	COG1376	ErfK ybiS ycfS ynhG family protein
GH799_16635	COG1388	LysM domain
GH799_16640	COG0415	Belongs to the DNA photolyase family
GH799_16645	COG0789	Transcriptional regulator
GH799_16650	COG3272	Protein of unknown function (DUF1722)
GH799_16660	COG0813	purine-nucleoside phosphorylase activity
GH799_16675	COG3706	GGDEF domain
GH799_16685	COG1566	PFAM secretion protein HlyD family protein
GH799_16690	COG4720	Psort location CytoplasmicMembrane, score
GH799_16695	COG1122	ATPase activity
GH799_16710	COG0348	domain, Protein
GH799_16715	COG0437	4 iron, 4 sulfur cluster binding
GH799_16720	COG1247	-acetyltransferase
GH799_16750	COG1067	ATP-dependent peptidase activity
GH799_16760	COG4172	Belongs to the ABC transporter superfamily
GH799_16765	COG1505	serine-type exopeptidase activity
GH799_16770	COG0583	DNA-binding transcription factor activity
GH799_16775	COG1620	l-lactate permease
GH799_16780	COG1304	FMN binding
GH799_16790	COG0668	transmembrane transport
GH799_16825	COG1063	alcohol dehydrogenase
GH799_16830	COG0156	8-amino-7-oxononanoate synthase activity
GH799_16840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GH799_16860	COG0745	RESPONSE REGULATOR receiver
GH799_16895	COG0346	lactoylglutathione lyase activity
GH799_16915	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GH799_16955	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GH799_16970	COG2204	response regulator
GH799_16995	COG1987	bacterial-type flagellum assembly
GH799_17005	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GH799_17020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GH799_17030	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GH799_17035	COG1516	flagellar protein fliS
GH799_17050	COG1580	Controls the rotational direction of flagella during chemotaxis
GH799_17055	COG1191	sigma factor activity
GH799_17060	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
GH799_17065	COG1360	Flagellar Motor Protein
GH799_17120	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GH799_17125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GH799_17135	COG0454	-acetyltransferase
GH799_17150	COG2814	Major facilitator Superfamily
GH799_17195	COG0628	permease
GH799_17200	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GH799_17210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GH799_17220	COG4628	conserved protein (DUF2132)
GH799_17225	COG0583	DNA-binding transcription factor activity
GH799_17250	COG1686	Belongs to the peptidase S11 family
GH799_17270	COG3397	chitin binding
GH799_17275	COG4667	esterase of the alpha-beta hydrolase superfamily
GH799_17280	COG2095	MarC family integral membrane protein
GH799_17300	COG3206	protein involved in exopolysaccharide biosynthesis
GH799_17300	COG0489	protein tyrosine kinase activity
GH799_17315	COG0583	DNA-binding transcription factor activity
GH799_17325	COG1301	dicarboxylic acid transport
GH799_17330	COG3339	Conserved Protein
GH799_17335	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GH799_17340	COG0700	Nucleoside recognition
GH799_17345	COG3366	ferrous iron transmembrane transporter activity
GH799_17360	COG0366	Alpha amylase catalytic
GH799_17365	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GH799_17370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GH799_17375	COG1640	4-alpha-glucanotransferase
GH799_17380	COG0058	SHG alpha-glucan phosphorylase activity
GH799_17395	COG2909	trisaccharide binding
GH799_17410	COG1999	signal sequence binding
GH799_17420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GH799_17420	COG1263	PTS System
GH799_17425	COG1162	GTPase activity
GH799_17430	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
GH799_17440	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
GH799_17450	COG0531	amino acid
GH799_17455	COG1982	Orn Lys Arg decarboxylase major
GH799_17475	COG2356	endonuclease I
GH799_17500	COG4580	involved in the transport of maltose and maltodextrins
GH799_17525	COG0739	heme binding
GH799_17535	COG0612	Peptidase, M16
GH799_17540	COG0840	transmembrane signaling receptor activity
GH799_17545	COG1120	ATPase activity
GH799_17550	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GH799_17555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GH799_17560	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GH799_17565	COG4772	TonB-dependent receptor
GH799_17590	COG4264	IucA IucC family
GH799_17595	COG0019	diaminopimelate decarboxylase activity
GH799_17600	COG1653	transport
GH799_17610	COG0745	RESPONSE REGULATOR receiver
GH799_17635	COG1172	Belongs to the binding-protein-dependent transport system permease family
GH799_17640	COG1129	ABC transporter
GH799_17645	COG1879	ABC-type sugar transport system periplasmic component
GH799_17650	COG1069	ribulokinase activity
GH799_17660	COG2160	L-arabinose isomerase activity
GH799_17685	COG1764	response to oxidative stress
GH799_17690	COG1846	Transcriptional regulator
GH799_17695	COG0450	alkyl hydroperoxide reductase
GH799_17700	COG3634	alkyl hydroperoxide reductase activity
GH799_17730	COG1595	DNA-templated transcription, initiation
GH799_17745	COG0840	transmembrane signaling receptor activity
GH799_17750	COG0583	DNA-binding transcription factor activity
GH799_17755	COG1486	melibiose metabolic process
GH799_17770	COG2258	MOSC domain
GH799_17775	COG0513	Belongs to the DEAD box helicase family
GH799_17785	COG2186	Transcriptional regulator
GH799_17795	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
GH799_17805	COG0246	Mannitol dehydrogenase
GH799_17810	COG1904	glucuronate isomerase
GH799_17815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GH799_17820	COG0800	Aldolase
GH799_17845	COG2207	Transcriptional regulator
GH799_17855	COG1132	(ABC) transporter
GH799_17900	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GH799_17930	COG0259	pyridoxamine-phosphate oxidase activity
GH799_17975	COG4166	transmembrane transport
GH799_17995	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GH799_18000	COG1263	PTS System
GH799_18000	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GH799_18005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
GH799_18010	COG3340	Belongs to the peptidase S51 family
GH799_18030	COG1444	tRNA N-acetyltransferase activity
GH799_18055	COG4608	Belongs to the ABC transporter superfamily
GH799_18060	COG0444	Belongs to the ABC transporter superfamily
GH799_18070	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
GH799_18070	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GH799_18095	COG0217	transcriptional regulatory protein
GH799_18100	COG0772	Belongs to the SEDS family
GH799_18115	COG1136	(ABC) transporter
GH799_18135	COG3275	phosphorelay sensor kinase activity
GH799_18140	COG3279	Response regulator of the LytR AlgR family
GH799_18150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GH799_18185	COG0786	glutamate:sodium symporter activity
GH799_18195	COG1131	(ABC) transporter
GH799_18200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GH799_18205	COG0786	glutamate:sodium symporter activity
GH799_18220	COG0363	glucosamine-6-phosphate deaminase activity
GH799_18240	COG1741	Belongs to the pirin family
GH799_18245	COG2259	Doxx family
GH799_18260	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GH799_18265	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GH799_18275	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
GH799_18315	COG3123	guanosine phosphorylase activity
GH799_18325	COG5001	Diguanylate cyclase
GH799_18335	COG0534	Mate efflux family protein
GH799_18340	COG0564	pseudouridine synthase activity
GH799_18355	COG0583	DNA-binding transcription factor activity
GH799_18360	COG0561	phosphatase activity
GH799_18370	COG2199	diguanylate cyclase activity
GH799_18385	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GH799_18390	COG2162	N-hydroxyarylamine O-acetyltransferase activity
GH799_18395	COG0583	DNA-binding transcription factor activity
GH799_18410	COG1414	Transcriptional regulator
GH799_18415	COG1028	Short-chain dehydrogenase reductase Sdr
GH799_18425	COG1917	Cupin 2, conserved barrel domain protein
GH799_18440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GH799_18445	COG0800	Aldolase
GH799_18465	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GH799_18470	COG0823	Involved in the tonB-independent uptake of proteins
GH799_18475	COG2375	cellular response to nickel ion
GH799_18505	COG1357	PFAM Pentapeptide repeats (8 copies)
GH799_18510	COG3047	cAMP biosynthetic process
GH799_18540	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
GH799_18540	COG3408	Glycogen debranching enzyme
GH799_18545	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GH799_18555	COG0583	DNA-binding transcription factor activity
GH799_18565	COG0583	DNA-binding transcription factor activity
GH799_18580	COG0546	phosphoglycolate phosphatase activity
GH799_18605	COG3835	regulator
GH799_18610	COG2610	gluconate transmembrane transporter activity
GH799_18615	COG1929	Belongs to the glycerate kinase type-1 family
GH799_18620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GH799_18640	COG0454	-acetyltransferase
GH799_18640	COG0456	acetyltransferase
GH799_18655	COG1028	Short-chain dehydrogenase reductase Sdr
GH799_18665	COG3005	denitrification pathway
GH799_18670	COG0243	molybdopterin cofactor binding
GH799_18680	COG0352	thiamine-phosphate diphosphorylase activity
GH799_18685	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GH799_18690	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GH799_18695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GH799_18700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GH799_18705	COG1116	anion transmembrane transporter activity
GH799_18710	COG0351	phosphomethylpyrimidine kinase
GH799_18720	COG0312	modulator of DNA gyrase
GH799_18725	COG0312	modulator of DNA gyrase
GH799_18730	COG1901	pseudouridine methyltransferase
GH799_18790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GH799_18800	COG0584	glycerophosphoryl diester phosphodiesterase
GH799_18810	COG0745	RESPONSE REGULATOR receiver
GH799_18830	COG0811	peptide transport
GH799_18835	COG0811	peptide transport
GH799_18840	COG0848	biopolymer transport protein
GH799_18885	COG0803	Belongs to the bacterial solute-binding protein 9 family
GH799_18890	COG1121	(ABC) transporter
GH799_18895	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GH799_18910	COG1770	oligopeptidase
GH799_18915	COG2814	Major facilitator Superfamily
GH799_18920	COG0010	Belongs to the arginase family
GH799_18925	COG1166	arginine decarboxylase activity
GH799_18935	COG4067	protein conserved in archaea
GH799_18935	COG0189	ligase activity
GH799_18940	COG0189	ligase activity
GH799_18945	COG0583	DNA-binding transcription factor activity
GH799_18990	COG3706	GGDEF domain
GH799_19020	COG0579	oxidoreductase
GH799_19030	COG3033	Beta-eliminating lyase
GH799_19050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GH799_19060	COG3145	DNA-N1-methyladenine dioxygenase activity
GH799_19065	COG3706	GGDEF domain
GH799_19070	COG0840	transmembrane signaling receptor activity
GH799_19085	COG3706	GGDEF domain
GH799_19090	COG0415	Belongs to the DNA photolyase family
GH799_19095	COG3046	protein related to deoxyribodipyrimidine photolyase
GH799_19110	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GH799_19110	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GH799_19115	COG1765	OsmC-like protein
GH799_19120	COG0110	maltose O-acetyltransferase activity
GH799_19160	COG1011	Hydrolase
GH799_19175	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
GH799_19185	COG2067	long-chain fatty acid transport protein
GH799_19190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GH799_19195	COG0577	efflux transmembrane transporter activity
GH799_19195	COG1136	(ABC) transporter
GH799_19205	COG3240	lipase activity
GH799_19235	COG1609	Transcriptional regulator
GH799_19240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GH799_19250	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GH799_19255	COG1840	ABC-type Fe3 transport system, periplasmic component
GH799_19265	COG3842	ATPase activity
GH799_19290	COG2990	Protein conserved in bacteria
GH799_19300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GH799_19305	COG2866	Carboxypeptidase
GH799_19320	COG0583	DNA-binding transcription factor activity
GH799_19345	COG1760	l-serine dehydratase
GH799_19365	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GH799_19375	COG0741	lytic transglycosylase activity
GH799_19395	COG1815	bacterial-type flagellum-dependent cell motility
GH799_19400	COG1558	bacterial-type flagellum-dependent cell motility
GH799_19405	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
GH799_19410	COG1749	Flagellar hook protein flgE
GH799_19415	COG4787	bacterial-type flagellum-dependent cell motility
GH799_19420	COG4786	Flagellar basal body rod
GH799_19425	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
GH799_19430	COG1706	bacterial-type flagellum-dependent cell motility
GH799_19445	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GH799_19465	COG1304	FMN binding
GH799_19495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GH799_19505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GH799_19510	COG0459	protein refolding
GH799_19525	COG1280	lysine exporter protein (LysE YggA)
GH799_19545	COG1309	transcriptional regulator
GH799_19555	COG0737	Belongs to the 5'-nucleotidase family
GH799_19560	COG2070	2-Nitropropane dioxygenase
GH799_19565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GH799_19580	COG0346	lactoylglutathione lyase activity
GH799_19585	COG1349	DNA-binding transcription factor activity
GH799_19595	COG0753	catalase activity
GH799_19605	COG1335	isochorismatase
GH799_19615	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GH799_19640	COG0583	DNA-binding transcription factor activity
GH799_19655	COG3713	MltA-interacting MipA family protein
GH799_19665	COG3015	lipoprotein NlpE involved in copper resistance
GH799_19675	COG1342	Belongs to the UPF0251 family
GH799_19700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GH799_19710	COG4948	Mandelate Racemase Muconate Lactonizing
GH799_19720	COG0583	DNA-binding transcription factor activity
GH799_19770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GH799_19825	COG3842	ATPase activity
GH799_19855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GH799_19875	COG3706	GGDEF domain
GH799_19895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GH799_19910	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
GH799_19915	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GH799_19935	COG0574	Belongs to the PEP-utilizing enzyme family
GH799_19935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GH799_19940	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
GH799_19945	COG0252	asparaginase activity
GH799_19955	COG0583	DNA-binding transcription factor activity
GH799_19975	COG3122	Protein conserved in bacteria
GH799_19990	COG1028	Short-chain dehydrogenase reductase Sdr
GH799_20000	COG1063	alcohol dehydrogenase
GH799_20005	COG1902	pentaerythritol trinitrate reductase activity
GH799_20020	COG0583	DNA-binding transcription factor activity
GH799_20030	COG0513	Belongs to the DEAD box helicase family
GH799_20075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GH799_20080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GH799_20080	COG2207	Transcriptional regulator
GH799_20110	COG2354	Protein conserved in bacteria
GH799_20115	COG0418	dihydroorotase activity
GH799_20125	COG0401	homolog of Blt101
GH799_20135	COG3217	Mosc domain protein beta barrel domain protein
GH799_20135	COG0633	Ferredoxin
GH799_20135	COG3217	Mosc domain protein beta barrel domain protein
GH799_20135	COG0633	Ferredoxin
GH799_20140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GH799_20145	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GH799_20185	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GH799_20190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GH799_20200	COG0848	biopolymer transport protein
GH799_20205	COG0811	peptide transport
GH799_20210	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
GH799_20220	COG3721	Heme iron utilization protein
GH799_20225	COG0748	coenzyme F420 binding
GH799_20235	COG0835	chemotaxis
GH799_20235	COG0784	Response regulator, receiver
GH799_20240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GH799_20255	COG2814	Major facilitator Superfamily
GH799_20290	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GH799_20295	COG0783	Belongs to the Dps family
GH799_20305	COG0583	DNA-binding transcription factor activity
GH799_20320	COG4934	collagen metabolic process
GH799_20330	COG0366	Alpha amylase catalytic
GH799_20350	COG2249	NAD(P)H dehydrogenase (quinone) activity
GH799_20355	COG0589	response to stress
GH799_20360	COG0488	(ABC) transporter
GH799_20365	COG1505	serine-type exopeptidase activity
GH799_20375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GH799_20385	COG2067	long-chain fatty acid transport protein
GH799_20395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GH799_20405	COG2199	diguanylate cyclase activity
GH799_20405	COG2203	Gaf domain
GH799_20425	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GH799_20450	COG3383	formate dehydrogenase (NAD+) activity
GH799_20465	COG0842	Transport permease protein
GH799_20470	COG1131	(ABC) transporter
GH799_20485	COG2706	6-phosphogluconolactonase activity
GH799_20495	COG1881	PFAM PEBP family protein
GH799_20505	COG0798	PFAM Bile acid sodium symporter
GH799_20525	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GH799_20530	COG2213	PTS system mannitol-specific
GH799_20535	COG1063	alcohol dehydrogenase
GH799_20545	COG1072	(Pantothenic acid kinase))
GH799_20550	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
GH799_20570	COG0814	amino acid
GH799_20610	COG0739	heme binding
GH799_20615	COG5001	Diguanylate cyclase
GH799_20620	COG0583	DNA-binding transcription factor activity
GH799_20625	COG2814	Major facilitator Superfamily
GH799_20650	COG0697	spore germination
GH799_20680	COG2207	Transcriptional regulator
GH799_20685	COG1280	lysine exporter protein (LysE YggA)
GH799_20695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GH799_20700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GH799_20710	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
GH799_20735	COG1612	heme a metabolic process
GH799_20740	COG0109	protoheme IX farnesyltransferase activity
GH799_20745	COG0545	Peptidyl-prolyl cis-trans isomerase
GH799_20780	COG1278	Cold shock
GH799_20785	COG3036	rescue of stalled ribosome
GH799_20800	COG2199	diguanylate cyclase activity
GH799_20820	COG1136	(ABC) transporter
GH799_20820	COG0577	efflux transmembrane transporter activity
GH799_20830	COG0840	transmembrane signaling receptor activity
GH799_20835	COG0783	Belongs to the Dps family
GH799_20845	COG2133	pyrroloquinoline quinone binding
GH799_20850	COG1454	alcohol dehydrogenase
GH799_20855	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GH799_20890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GH799_20895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GH799_20900	COG3186	Phenylalanine-4-hydroxylase
GH799_20905	COG2154	pterin-4-alpha-carbinolamine dehydratase
GH799_20930	COG3530	Putative quorum-sensing-regulated virulence factor
GH799_20935	COG0513	Belongs to the DEAD box helicase family
GH799_20940	COG4628	conserved protein (DUF2132)
GH799_20945	COG0133	tryptophan synthase activity
GH799_20955	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GH799_20965	COG0523	cobalamin synthesis protein
GH799_20970	COG0513	Belongs to the DEAD box helicase family
GH799_20990	COG2200	EAL domain
GH799_20995	COG1119	ATPase activity
GH799_21000	COG0840	transmembrane signaling receptor activity
GH799_21025	COG0641	radical SAM
GH799_21045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GH799_21060	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GH799_21065	COG0513	Belongs to the DEAD box helicase family
GH799_21070	COG5001	Diguanylate cyclase
GH799_21080	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GH799_21095	COG5413	integral membrane protein
GH799_21105	COG1024	Enoyl-CoA hydratase
GH799_21110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GH799_21115	COG1960	acyl-CoA dehydrogenase activity
GH799_21125	COG0183	Belongs to the thiolase family
GH799_21140	COG1024	Enoyl-CoA hydratase
GH799_21145	COG1024	Enoyl-CoA hydratase
GH799_21155	COG1028	Short-chain dehydrogenase reductase Sdr
GH799_21160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GH799_21165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GH799_21170	COG1845	cytochrome c oxidase, subunit III
GH799_21175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GH799_21180	COG0109	protoheme IX farnesyltransferase activity
GH799_21185	COG1902	pentaerythritol trinitrate reductase activity
GH799_21195	COG1126	abc transporter atp-binding protein
GH799_21200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GH799_21205	COG4215	(ABC) transporter
GH799_21210	COG4160	amino acid transport
GH799_21225	COG0625	glutathione transferase activity
GH799_21260	COG0443	Heat shock 70 kDa protein
GH799_21265	COG2847	Copper chaperone PCu(A)C
GH799_21290	COG4607	ABC-type enterochelin transport system periplasmic component
GH799_21295	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GH799_21300	COG4605	iron ion homeostasis
GH799_21305	COG4604	ABC transporter, ATP-binding protein
GH799_21310	COG0789	Transcriptional regulator
GH799_21325	COG4771	TonB-dependent receptor
GH799_21325	COG1629	transport
GH799_21360	COG1289	transmembrane transporter activity
GH799_21365	COG0210	DNA helicase
GH799_21370	COG1803	Methylglyoxal synthase
GH799_21375	COG1879	ABC-type sugar transport system periplasmic component
GH799_21380	COG2205	protein histidine kinase activity
GH799_21380	COG0784	Response regulator, receiver
GH799_21380	COG2198	Histidine kinase
GH799_21395	COG0745	RESPONSE REGULATOR receiver
GH799_21400	COG3119	arylsulfatase activity
GH799_21405	COG3119	arylsulfatase activity
GH799_21420	COG3119	arylsulfatase activity
GH799_21425	COG0641	radical SAM
GH799_21430	COG0714	Associated with various cellular activities
GH799_21460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GH799_21460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GH799_21465	COG0583	DNA-binding transcription factor activity
GH799_21470	COG1597	lipid kinase activity
GH799_21475	COG3111	PFAM Bacterial OB fold (BOF) protein
GH799_21495	COG0641	radical SAM
GH799_21525	COG0501	Belongs to the peptidase M48B family
GH799_21530	COG1704	LemA family
GH799_21535	COG3069	C4-dicarboxylate transmembrane transporter activity
GH799_21545	COG1214	PFAM Peptidase M22, glycoprotease
GH799_21545	COG0456	acetyltransferase
GH799_21565	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GH799_21585	COG2207	Transcriptional regulator
GH799_21610	COG4964	Belongs to the GSP D family
GH799_21670	COG0583	DNA-binding transcription factor activity
GH799_21675	COG0583	DNA-binding transcription factor activity
GH799_21690	COG5001	Diguanylate cyclase
GH799_21690	COG3300	MHYT domain
GH799_21695	COG2197	response regulator
GH799_21700	COG3706	GGDEF domain
GH799_21710	COG2197	response regulator
GH799_21735	COG0835	chemotaxis
GH799_21735	COG0784	Response regulator, receiver
GH799_21755	COG2962	Rard protein
GH799_21770	COG0671	phosphoesterase, PA-phosphatase related
GH799_21785	COG2076	Multidrug Resistance protein
GH799_21815	COG0471	metal ion transport
GH799_21820	COG3290	protein histidine kinase activity
GH799_21825	COG4565	transcriptional regulatory protein
GH799_21835	COG0069	glutamate synthase activity
GH799_21835	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GH799_21845	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GH799_21870	COG1902	pentaerythritol trinitrate reductase activity
GH799_21875	COG0346	lactoylglutathione lyase activity
GH799_21895	COG2239	Acts as a magnesium transporter
GH799_21925	COG0242	peptide deformylase activity
GH799_21970	COG2176	DNA-directed DNA polymerase activity
GH799_21975	COG0583	DNA-binding transcription factor activity
GH799_21980	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GH799_21985	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GH799_22000	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GH799_22000	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GH799_22005	COG0509	glycine decarboxylation via glycine cleavage system
GH799_22010	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GH799_22050	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GH799_22050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GH799_22050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GH799_22055	COG1105	Belongs to the carbohydrate kinase PfkB family
GH799_22060	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GH799_22060	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GH799_22065	COG1609	Transcriptional regulator
GH799_22085	COG2203	Gaf domain
GH799_22085	COG2199	diguanylate cyclase activity
GH799_22085	COG2200	EAL domain
GH799_22090	COG0765	amino acid transport
GH799_22095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GH799_22100	COG0765	amino acid transport
GH799_22105	COG1126	abc transporter atp-binding protein
GH799_22110	COG0469	pyruvate kinase activity
GH799_22115	COG2271	Major facilitator Superfamily
GH799_22120	COG1840	ABC-type Fe3 transport system, periplasmic component
GH799_22140	COG1979	alcohol dehydrogenase
GH799_22145	COG2207	Transcriptional regulator
GH799_22160	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GH799_22165	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GH799_22170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GH799_22190	COG3437	response regulator, receiver
GH799_22190	COG0784	Response regulator, receiver
GH799_22200	COG0546	phosphoglycolate phosphatase activity
GH799_22205	COG0840	transmembrane signaling receptor activity
GH799_22215	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
GH799_22220	COG0513	Belongs to the DEAD box helicase family
GH799_22225	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GH799_22240	COG3038	cytochrome b561
GH799_22245	COG2353	YceI-like domain
GH799_22250	COG2116	formate transmembrane transporter activity
GH799_22255	COG0583	DNA-binding transcription factor activity
GH799_22265	COG3593	DNA synthesis involved in DNA repair
GH799_22270	COG0737	Belongs to the 5'-nucleotidase family
GH799_22275	COG0861	Integral membrane protein TerC family
GH799_22290	COG1943	Transposase
GH799_22295	COG2267	carboxylic ester hydrolase activity
GH799_22300	COG2067	long-chain fatty acid transport protein
GH799_22315	COG2050	protein possibly involved in aromatic compounds catabolism
GH799_22325	COG4533	DNA binding
GH799_22350	COG0484	heat shock protein binding
GH799_22360	COG5001	Diguanylate cyclase
GH799_22360	COG3300	MHYT domain
GH799_22365	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GH799_22375	COG4181	ATPase activity
GH799_22380	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GH799_22390	COG1984	allophanate hydrolase subunit 2
GH799_22395	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GH799_22400	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GH799_22405	COG3447	MASE1 domain protein
GH799_22405	COG5002	protein histidine kinase activity
GH799_22405	COG5001	Diguanylate cyclase
GH799_22410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GH799_22420	COG1629	transport
GH799_22420	COG4771	TonB-dependent receptor
GH799_22425	COG0583	DNA-binding transcription factor activity
GH799_22430	COG0045	succinate-CoA ligase (ADP-forming) activity
GH799_22430	COG1042	CoA-binding domain protein
GH799_22430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GH799_22440	COG1181	Belongs to the D-alanine--D-alanine ligase family
GH799_22450	COG0023	Translation Initiation Factor
GH799_22465	COG0589	response to stress
GH799_22470	COG3140	Belongs to the UPF0181 family
GH799_22495	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GH799_22500	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GH799_22515	COG3706	GGDEF domain
GH799_22515	COG0745	RESPONSE REGULATOR receiver
GH799_22525	COG5001	Diguanylate cyclase
GH799_22525	COG2203	Gaf domain
GH799_22525	COG3706	GGDEF domain
GH799_22525	COG4251	negative regulation of phosphorylation
GH799_22535	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GH799_22540	COG4149	molybdate abc transporter
GH799_22545	COG0725	ABC transporter, periplasmic molybdate-binding protein
GH799_22550	COG1492	cobalamin metabolic process
GH799_22555	COG3111	PFAM Bacterial OB fold (BOF) protein
GH799_22565	COG4067	protein conserved in archaea
GH799_22565	COG0189	ligase activity
GH799_22585	COG0534	Mate efflux family protein
GH799_22590	COG0602	queuosine metabolic process
GH799_22595	COG1328	CTP reductase activity
GH799_22610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GH799_22640	COG0243	molybdopterin cofactor binding
GH799_22650	COG0583	DNA-binding transcription factor activity
GH799_22655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GH799_22665	COG2197	response regulator
GH799_22670	COG3851	Histidine kinase
GH799_22675	COG2271	Major facilitator Superfamily
GH799_22700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GH799_22705	COG3118	belongs to the thioredoxin family
GH799_22710	COG2814	Major facilitator Superfamily
GH799_22720	COG0534	Mate efflux family protein
GH799_22750	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GH799_22770	COG2116	formate transmembrane transporter activity
GH799_22775	COG2146	nitrite reductase [NAD(P)H] activity
GH799_22780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GH799_22785	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GH799_22825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GH799_22825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GH799_22870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GH799_22890	COG0277	FAD linked oxidase domain protein
GH799_22895	COG0583	DNA-binding transcription factor activity
GH799_22915	COG2425	protein containing a von Willebrand factor type A (vWA) domain
GH799_22930	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
GH799_22945	COG1288	antiporter activity
GH799_22955	COG2814	Major facilitator Superfamily
GH799_22965	COG3040	lipid binding
GH799_22985	COG0419	ATPase involved in DNA repair
GH799_22990	COG0420	3'-5' exonuclease activity
GH799_23005	COG3501	Rhs element vgr protein
GH799_23060	COG0631	protein serine/threonine phosphatase activity
GH799_23095	COG2815	serine threonine protein kinase
GH799_23095	COG0515	serine threonine protein kinase
GH799_23150	COG2146	nitrite reductase [NAD(P)H] activity
GH799_23150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GH799_23155	COG1116	anion transmembrane transporter activity
GH799_23160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GH799_23165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GH799_23165	COG1116	anion transmembrane transporter activity
GH799_23175	COG3707	response regulator
GH799_23195	COG1648	precorrin-2 dehydrogenase activity
GH799_23195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GH799_23200	COG0243	molybdopterin cofactor binding
GH799_23205	COG0456	acetyltransferase
GH799_23210	COG0814	amino acid
GH799_23220	COG0745	RESPONSE REGULATOR receiver
GH799_23220	COG3706	GGDEF domain
GH799_23240	COG1785	Belongs to the alkaline phosphatase family
GH799_23255	COG0745	RESPONSE REGULATOR receiver
GH799_23275	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
GH799_23290	COG1609	Transcriptional regulator
GH799_23295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GH799_23300	COG1879	ABC-type sugar transport system periplasmic component
GH799_23305	COG1172	Belongs to the binding-protein-dependent transport system permease family
GH799_23310	COG1129	ABC transporter
GH799_23315	COG1869	D-ribose catabolic process
GH799_23320	COG5001	Diguanylate cyclase
GH799_23325	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GH799_23385	COG2205	protein histidine kinase activity
GH799_23385	COG0784	Response regulator, receiver
GH799_23405	COG3300	MHYT domain
GH799_23405	COG5001	Diguanylate cyclase
GH799_23415	COG0330	HflC and HflK could
GH799_23430	COG4175	Glycine betaine
GH799_23430	COG0517	IMP dehydrogenase activity
GH799_23435	COG4176	ABC-type proline glycine betaine transport system permease component
GH799_23450	COG1012	belongs to the aldehyde dehydrogenase family
GH799_23455	COG1309	transcriptional regulator
GH799_23460	COG3706	GGDEF domain
GH799_23485	COG1024	Enoyl-CoA hydratase
GH799_23490	COG1960	acyl-CoA dehydrogenase activity
GH799_23500	COG0183	Belongs to the thiolase family
GH799_23510	COG1960	acyl-CoA dehydrogenase activity
GH799_23515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GH799_23525	COG0439	Biotin carboxylase
GH799_23535	COG4999	Histidine kinase
GH799_23535	COG3437	response regulator, receiver
GH799_23535	COG2205	protein histidine kinase activity
GH799_23535	COG3850	Histidine kinase
GH799_23550	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
GH799_23550	COG3264	Mechanosensitive ion channel
GH799_23560	COG0110	maltose O-acetyltransferase activity
GH799_23565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GH799_23570	COG1271	oxidase subunit
GH799_23575	COG1294	oxidase, subunit
GH799_23585	COG0384	phenazine biosynthesis protein PhzF
GH799_23590	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GH799_23595	COG0789	Transcriptional regulator
GH799_23605	COG3474	cytochrome
GH799_23610	COG1013	pyruvate-flavodoxin oxidoreductase activity
GH799_23615	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
GH799_23615	COG0674	pyruvate-flavodoxin oxidoreductase activity
GH799_23685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GH799_23690	COG0516	GMP reductase activity
GH799_23695	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GH799_23695	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GH799_23710	COG4989	oxidoreductase activity
GH799_23725	COG0038	chloride channel
GH799_23735	COG1914	H( )-stimulated, divalent metal cation uptake system
GH799_23740	COG0302	gtp cyclohydrolase
GH799_23750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GH799_23770	COG2897	thiosulfate sulfurtransferase activity
GH799_23795	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GH799_23800	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GH799_23805	COG0840	transmembrane signaling receptor activity
GH799_23815	COG2814	Major facilitator Superfamily
GH799_23820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GH799_23830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GH799_23840	COG0840	transmembrane signaling receptor activity
GH799_23860	COG2195	Cleaves the N-terminal amino acid of tripeptides
GH799_23875	COG2197	response regulator
GH799_23880	COG3850	Histidine kinase
GH799_23885	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GH799_23895	COG0243	molybdopterin cofactor binding
GH799_23905	COG3005	denitrification pathway
GH799_23925	COG0183	Belongs to the thiolase family
GH799_23945	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GH799_23950	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GH799_23975	COG1522	sequence-specific DNA binding
GH799_23995	COG1566	PFAM secretion protein HlyD family protein
GH799_24005	COG0784	Response regulator, receiver
GH799_24005	COG2205	protein histidine kinase activity
GH799_24010	COG1879	ABC-type sugar transport system periplasmic component
GH799_24015	COG2827	Endonuclease containing a URI domain
GH799_24020	COG3132	Protein of unknown function, DUF480
GH799_24035	COG2926	Belongs to the UPF0265 family
GH799_24040	COG0534	Mate efflux family protein
GH799_24045	COG0673	inositol 2-dehydrogenase activity
GH799_24050	COG5002	protein histidine kinase activity
GH799_24050	COG0784	Response regulator, receiver
GH799_24050	COG2205	protein histidine kinase activity
GH799_24075	COG1522	sequence-specific DNA binding
GH799_24085	COG0531	amino acid
GH799_24100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GH799_24105	COG2239	Acts as a magnesium transporter
GH799_24115	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GH799_24120	COG0402	S-adenosylhomocysteine deaminase activity
GH799_24130	COG1418	mRNA catabolic process
GH799_24145	COG2814	Major facilitator Superfamily
GH799_24155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GH799_24175	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GH799_24195	COG4221	oxidoreductase activity
GH799_24200	COG0745	RESPONSE REGULATOR receiver
GH799_24205	COG2205	protein histidine kinase activity
GH799_24215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
GH799_24220	COG2194	sulfuric ester hydrolase activity
GH799_24225	COG0673	inositol 2-dehydrogenase activity
GH799_24250	COG1846	Transcriptional regulator
GH799_24260	COG4667	esterase of the alpha-beta hydrolase superfamily
GH799_24265	COG1741	Belongs to the pirin family
GH799_24270	COG1278	Cold shock
GH799_24290	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GH799_24315	COG1686	Belongs to the peptidase S11 family
GH799_24325	COG0625	glutathione transferase activity
GH799_24335	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GH799_24360	COG1028	Short-chain dehydrogenase reductase Sdr
GH799_24380	COG3746	phosphate-selective porin O and P
GH799_24400	COG0183	Belongs to the thiolase family
GH799_24480	COG0804	urea catabolic process
GH799_24500	COG0747	negative chemotaxis
GH799_24510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GH799_24515	COG4172	Belongs to the ABC transporter superfamily
GH799_24525	COG2207	Transcriptional regulator
GH799_24545	COG2916	Histone family protein nucleoid-structuring protein H-NS
GH799_24635	COG4790	Type iii secretion
GH799_24650	COG3710	Transcriptional regulator
GH799_24680	COG4792	protein secretion
GH799_24685	COG4789	Type iii secretion
GH799_24790	COG2202	Pas domain
GH799_24790	COG2200	EAL domain
GH799_24790	COG2199	diguanylate cyclase activity
GH799_24835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GH799_24925	COG3833	ABC-type maltose transport systems, permease component
GH799_24930	COG1175	transmembrane transport
GH799_24940	COG3842	ATPase activity
GH799_25005	COG1309	transcriptional regulator
GH799_25010	COG2130	NADP-dependent
GH799_25020	COG0753	catalase activity
GH799_25025	COG2084	Dehydrogenase
GH799_25030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GH799_25035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GH799_25045	COG2207	Transcriptional regulator
GH799_25050	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GH799_25050	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GH799_25050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GH799_25065	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GH799_25070	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GH799_25075	COG3300	MHYT domain
GH799_25075	COG5001	Diguanylate cyclase
GH799_25080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GH799_25085	COG0569	domain protein
GH799_25095	COG5002	protein histidine kinase activity
GH799_25100	COG1132	(ABC) transporter
GH799_25105	COG4774	siderophore transport
GH799_25110	COG1120	ATPase activity
GH799_25115	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
GH799_25165	COG2197	response regulator
GH799_25175	COG0840	transmembrane signaling receptor activity
GH799_25185	COG0714	Associated with various cellular activities