locus-tag	class	description
D0871_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
D0871_00015	COG0592	DNA-directed DNA polymerase activity
D0871_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
D0871_00025	COG0187	DNA topoisomerase II activity
D0871_00045	COG0071	Belongs to the small heat shock protein (HSP20) family
D0871_00050	COG3977	Valine--pyruvate aminotransferase
D0871_00055	COG0366	Alpha amylase catalytic
D0871_00060	COG0751	glycine-tRNA ligase activity
D0871_00065	COG0752	glycyl-tRNA synthetase alpha subunit
D0871_00070	COG2119	membrane
D0871_00080	COG0425	Belongs to the sulfur carrier protein TusA family
D0871_00095	COG0604	alcohol dehydrogenase
D0871_00100	COG0183	Belongs to the thiolase family
D0871_00105	COG1024	Enoyl-CoA hydratase
D0871_00105	COG1250	3-hydroxyacyl-CoA dehydrogenase
D0871_00110	COG1739	Uncharacterized protein family UPF0029
D0871_00115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0871_00170	COG0582	viral genome integration into host DNA
D0871_00180	COG4735	regulation of single-species biofilm formation
D0871_00185	COG2003	Belongs to the UPF0758 family
D0871_00340	COG3501	Rhs element vgr protein
D0871_00425	COG0328	RNA-DNA hybrid ribonuclease activity
D0871_00460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
D0871_00465	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
D0871_00475	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D0871_00480	COG2104	thiamine diphosphate biosynthetic process
D0871_00485	COG2022	thiamine diphosphate biosynthetic process
D0871_00495	COG0006	proline dipeptidase activity
D0871_00495	COG0006	proline dipeptidase activity
D0871_00525	COG3220	belongs to the UPF0276 family
D0871_00535	COG0210	DNA helicase
D0871_00545	COG0405	Gamma-glutamyltransferase
D0871_00550	COG1280	lysine exporter protein (LysE YggA)
D0871_00560	COG2962	Rard protein
D0871_00565	COG0514	ATP-dependent DNA helicase (RecQ)
D0871_00580	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
D0871_00585	COG0248	Ppx GppA phosphatase
D0871_00590	COG0513	Belongs to the DEAD box helicase family
D0871_00595	COG3118	belongs to the thioredoxin family
D0871_00600	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
D0871_00615	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
D0871_00620	COG0633	Ferredoxin
D0871_00675	COG3071	HemY protein
D0871_00680	COG2959	enzyme of heme biosynthesis
D0871_00685	COG1587	Uroporphyrinogen-III synthase
D0871_00690	COG0181	hydroxymethylbilane synthase activity
D0871_00695	COG3072	Adenylate cyclase
D0871_00700	COG1965	Belongs to the frataxin family
D0871_00710	COG0019	diaminopimelate decarboxylase activity
D0871_00715	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
D0871_00725	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D0871_00730	COG1011	Hydrolase
D0871_00735	COG2200	EAL domain
D0871_00735	COG3287	FIST C domain
D0871_00735	COG2199	diguanylate cyclase activity
D0871_00755	COG0561	phosphatase activity
D0871_00765	COG2267	carboxylic ester hydrolase activity
D0871_00770	COG1280	lysine exporter protein (LysE YggA)
D0871_00775	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D0871_00780	COG0640	Transcriptional regulator
D0871_00785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0871_00840	COG2095	MarC family integral membrane protein
D0871_00850	COG0742	ribosomal rna small subunit methyltransferase
D0871_00855	COG0552	protein localization to endoplasmic reticulum
D0871_00860	COG2884	Cell division ATP-binding protein ftsE
D0871_00865	COG2177	Part of the ABC transporter FtsEX involved in
D0871_00880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0871_00885	COG0705	Rhomboid family
D0871_00890	COG1580	Controls the rotational direction of flagella during chemotaxis
D0871_00895	COG3161	chorismate lyase activity
D0871_00900	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D0871_00905	COG2937	Belongs to the GPAT DAPAT family
D0871_00920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D0871_00925	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
D0871_00930	COG0534	Mate efflux family protein
D0871_00935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0871_00950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0871_00955	COG4206	TonB-dependent receptor
D0871_00965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D0871_01030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0871_01040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
D0871_01080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D0871_01090	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0871_01095	COG0250	Participates in transcription elongation, termination and antitermination
D0871_01100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
D0871_01105	COG0081	regulation of translation
D0871_01110	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
D0871_01115	COG0222	ribosome binding
D0871_01120	COG0085	RNA polymerase activity
D0871_01125	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
D0871_01130	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
D0871_01135	COG2816	NAD+ diphosphatase activity
D0871_01150	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
D0871_01155	COG1573	uracil-dna glycosylase
D0871_01160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0871_01165	COG3068	Protein conserved in bacteria
D0871_01170	COG1253	flavin adenine dinucleotide binding
D0871_01185	COG0151	Belongs to the GarS family
D0871_01195	COG0138	bifunctional purine biosynthesis protein purh
D0871_01205	COG0789	Transcriptional regulator
D0871_01210	COG3710	Transcriptional regulator
D0871_01220	COG0531	amino acid
D0871_01225	COG1982	Orn Lys Arg decarboxylase major
D0871_01295	COG3335	DDE superfamily endonuclease
D0871_01305	COG3706	GGDEF domain
D0871_01310	COG0488	(ABC) transporter
D0871_01315	COG2814	Major facilitator Superfamily
D0871_01320	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
D0871_01325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0871_01330	COG2264	protein methyltransferase activity
D0871_01340	COG0439	Biotin carboxylase
D0871_01345	COG0511	ligase activity, forming carbon-carbon bonds
D0871_01350	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
D0871_01355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0871_01370	COG2814	Major facilitator Superfamily
D0871_01375	COG2205	protein histidine kinase activity
D0871_01375	COG0784	Response regulator, receiver
D0871_01400	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0871_01410	COG3263	regulation of cellular component size
D0871_01420	COG4232	protein-disulfide reductase activity
D0871_01425	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D0871_01430	COG1027	Aspartate ammonia-lyase
D0871_01435	COG3030	protein affecting phage T7 exclusion by the F plasmid
D0871_01440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D0871_01450	COG2205	protein histidine kinase activity
D0871_01455	COG0745	RESPONSE REGULATOR receiver
D0871_01465	COG3678	ATP-independent chaperone mediated protein folding
D0871_01475	COG0205	6-phosphofructokinase activity
D0871_01480	COG0534	Mate efflux family protein
D0871_01485	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D0871_01490	COG0459	protein refolding
D0871_01510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D0871_01520	COG1509	lysine 2,3-aminomutase activity
D0871_01525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D0871_01535	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
D0871_01540	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
D0871_01545	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D0871_01550	COG1053	succinate dehydrogenase
D0871_01560	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
D0871_01580	COG4942	peptidase
D0871_01585	COG1045	serine acetyltransferase
D0871_01590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
D0871_01595	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
D0871_01600	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0871_01605	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D0871_01620	COG0471	metal ion transport
D0871_01625	COG0688	phosphatidylethanolamine metabolic process
D0871_01630	COG1162	GTPase activity
D0871_01635	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
D0871_01705	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D0871_01710	COG0802	atpase or kinase
D0871_01720	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D0871_01725	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
D0871_01735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D0871_01740	COG0330	HflC and HflK could
D0871_01745	COG0330	HflC and HflK could
D0871_01750	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
D0871_01755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D0871_01765	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
D0871_01770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0871_01770	COG1017	nitric oxide dioxygenase activity
D0871_01775	COG1959	2 iron, 2 sulfur cluster binding
D0871_01780	COG0557	exoribonuclease II activity
D0871_01785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0871_01790	COG0546	phosphoglycolate phosphatase activity
D0871_01795	COG0180	Tryptophanyl-tRNA synthetase
D0871_01825	COG0512	Glutamine amidotransferase of anthranilate synthase
D0871_01830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D0871_01840	COG1012	belongs to the aldehyde dehydrogenase family
D0871_01850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0871_01855	COG3954	Phosphoribulokinase
D0871_01860	COG3089	Belongs to the UPF0270 family
D0871_01865	COG0429	hydrolase of the alpha beta-hydrolase fold
D0871_01875	COG0488	(ABC) transporter
D0871_01885	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0871_01900	COG1047	Peptidyl-prolyl cis-trans
D0871_01910	COG1446	asparaginase
D0871_01915	COG2900	Belongs to the SlyX family
D0871_01925	COG0545	Peptidyl-prolyl cis-trans isomerase
D0871_01930	COG2964	Protein conserved in bacteria
D0871_01935	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
D0871_01940	COG2923	Belongs to the DsrF TusC family
D0871_01955	COG0049	tRNA binding
D0871_01960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D0871_01965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
D0871_01970	COG2906	2 iron, 2 sulfur cluster binding
D0871_01980	COG0281	malic enzyme
D0871_01990	COG0626	cystathionine gamma-synthase activity
D0871_01995	COG0460	homoserine dehydrogenase
D0871_01995	COG0527	aspartate kinase activity
D0871_02000	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D0871_02010	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
D0871_02015	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0871_02020	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
D0871_02025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D0871_02030	COG0137	argininosuccinate synthase activity
D0871_02035	COG0165	Argininosuccinate lyase
D0871_02035	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D0871_02050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D0871_02050	COG0678	peroxiredoxin activity
D0871_02060	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
D0871_02090	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
D0871_02095	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
D0871_02105	COG0338	D12 class N6 adenine-specific DNA methyltransferase
D0871_02110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D0871_02115	COG0360	Binds together with S18 to 16S ribosomal RNA
D0871_02120	COG2965	DNA replication, synthesis of RNA primer
D0871_02130	COG0359	binds to the 23S rRNA
D0871_02140	COG0305	Participates in initiation and elongation during chromosome replication
D0871_02145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D0871_02155	COG0432	Pfam Uncharacterised protein family UPF0047
D0871_02160	COG0166	Belongs to the GPI family
D0871_02170	COG0735	belongs to the Fur family
D0871_02180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0871_02205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0871_02210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0871_02215	COG0175	sulfate reduction
D0871_02285	COG3335	DDE superfamily endonuclease
D0871_02310	COG1410	methionine synthase
D0871_02310	COG0646	methionine synthase
D0871_02315	COG0527	aspartate kinase activity
D0871_02325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D0871_02335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D0871_02350	COG0629	single-stranded DNA binding
D0871_02355	COG2199	diguanylate cyclase activity
D0871_02355	COG2200	EAL domain
D0871_02380	COG3267	Type II secretory pathway component ExeA
D0871_02380	COG3409	Peptidoglycan-binding domain 1 protein
D0871_02390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0871_02395	COG1459	type II secretion system
D0871_02405	COG4969	Belongs to the N-Me-Phe pilin family
D0871_02440	COG1077	Cell shape determining protein MreB Mrl
D0871_02445	COG1792	Involved in formation and maintenance of cell shape
D0871_02450	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D0871_02455	COG0424	maF-like protein
D0871_02460	COG1530	ribonuclease E activity
D0871_02465	COG3164	Protein of unknown function
D0871_02470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D0871_02475	COG0312	modulator of DNA gyrase
D0871_02480	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
D0871_02485	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0871_02500	COG0564	pseudouridine synthase activity
D0871_02505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0871_02510	COG3028	Belongs to the UPF0307 family
D0871_02515	COG0312	modulator of DNA gyrase
D0871_02520	COG2239	Acts as a magnesium transporter
D0871_02525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0871_02530	COG1660	Displays ATPase and GTPase activities
D0871_02535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0871_02540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D0871_02550	COG1137	ATPase activity
D0871_02555	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
D0871_02565	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D0871_02565	COG0517	IMP dehydrogenase activity
D0871_02575	COG1127	ABC transporter
D0871_02580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D0871_02585	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D0871_02590	COG2854	intermembrane phospholipid transfer
D0871_02600	COG5007	Belongs to the BolA IbaG family
D0871_02605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D0871_02610	COG0204	Acyl-transferase
D0871_02615	COG0251	oxidation-reduction process
D0871_02620	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
D0871_02625	COG0540	Belongs to the ATCase OTCase family
D0871_02635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
D0871_02640	COG2235	arginine
D0871_02670	COG0525	valine-tRNA ligase activity
D0871_02675	COG2927	DNA polymerase III (CHI subunit)
D0871_02680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D0871_02685	COG0795	lipopolysaccharide-transporting ATPase activity
D0871_02690	COG0795	lipopolysaccharide-transporting ATPase activity
D0871_02700	COG4325	translation initiation factor activity
D0871_02705	COG1028	Short-chain dehydrogenase reductase Sdr
D0871_02720	COG0726	polysaccharide deacetylase
D0871_02725	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0871_02730	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
D0871_02735	COG1447	Phosphotransferase system cellobiose-specific component IIA
D0871_02740	COG1486	melibiose metabolic process
D0871_02745	COG3394	polysaccharide catabolic process
D0871_02755	COG3437	response regulator, receiver
D0871_02800	COG1012	belongs to the aldehyde dehydrogenase family
D0871_02870	COG0741	lytic transglycosylase activity
D0871_02875	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
D0871_02885	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D0871_02895	COG2066	Belongs to the glutaminase family
D0871_02900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0871_02905	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D0871_02915	COG1872	DUF167
D0871_02920	COG0762	integral membrane protein
D0871_02925	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
D0871_02930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
D0871_02945	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D0871_02950	COG1678	Uncharacterized ACR, COG1678
D0871_02955	COG0189	ligase activity
D0871_02960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D0871_02965	COG2356	endonuclease I
D0871_02970	COG3091	SprT-like family
D0871_02980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
D0871_02990	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D0871_02995	COG0583	DNA-binding transcription factor activity
D0871_03000	COG4771	TonB-dependent receptor
D0871_03005	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0871_03010	COG0126	phosphoglycerate kinase activity
D0871_03015	COG0191	fructose-bisphosphate aldolase activity
D0871_03020	COG0668	transmembrane transport
D0871_03025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D0871_03035	COG0583	DNA-binding transcription factor activity
D0871_03045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0871_03050	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
D0871_03055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D0871_03065	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
D0871_03075	COG3079	Belongs to the UPF0149 family
D0871_03080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0871_03085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0871_03100	COG0354	folic acid binding
D0871_03105	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D0871_03115	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
D0871_03125	COG1595	DNA-templated transcription, initiation
D0871_03130	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
D0871_03140	COG3086	response to oxidative stress
D0871_03145	COG0481	GTPase activity
D0871_03150	COG0681	Belongs to the peptidase S26 family
D0871_03155	COG0571	ribonuclease III activity
D0871_03160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D0871_03165	COG1381	Involved in DNA repair and RecF pathway recombination
D0871_03170	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D0871_03175	COG0736	holo-[acyl-carrier-protein] synthase activity
D0871_03190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
D0871_03200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D0871_03205	COG3956	TIGRFAM MazG family protein
D0871_03210	COG0504	CTP synthase activity
D0871_03215	COG0148	phosphopyruvate hydratase activity
D0871_03220	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D0871_03225	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D0871_03230	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
D0871_03235	COG0585	pseudouridine synthase activity
D0871_03240	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
D0871_03245	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D0871_03260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
D0871_03265	COG1546	Belongs to the CinA family
D0871_03270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
D0871_03275	COG2137	regulation of response to DNA damage stimulus
D0871_03280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D0871_03285	COG0527	aspartate kinase activity
D0871_03345	COG3630	sodium ion export across plasma membrane
D0871_03350	COG5016	pyruvate
D0871_03350	COG0511	ligase activity, forming carbon-carbon bonds
D0871_03355	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
D0871_03360	COG1063	alcohol dehydrogenase
D0871_03365	COG1238	metal cluster binding
D0871_03370	COG0612	Peptidase, M16
D0871_03375	COG2918	glutathione biosynthetic process
D0871_03385	COG1854	S-ribosylhomocysteine lyase activity
D0871_03390	COG4536	flavin adenine dinucleotide binding
D0871_03395	COG4137	Cytochrome C assembly protein
D0871_03400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D0871_03405	COG0228	four-way junction DNA binding
D0871_03410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D0871_03415	COG0336	Belongs to the RNA methyltransferase TrmD family
D0871_03420	COG0335	large ribosomal subunit rRNA binding
D0871_03425	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
D0871_03430	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
D0871_03435	COG0237	dephospho-CoA kinase activity
D0871_03445	COG1459	type II secretion system
D0871_03450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0871_03460	COG0157	Belongs to the NadC ModD family
D0871_03470	COG2186	Transcriptional regulator
D0871_03475	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
D0871_03480	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0871_03485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0871_03500	COG0288	reversible hydration of carbon dioxide
D0871_03505	COG0659	secondary active sulfate transmembrane transporter activity
D0871_03515	COG1131	(ABC) transporter
D0871_03520	COG0842	Transport permease protein
D0871_03530	COG1560	Kdo2-lipid A biosynthetic process
D0871_03540	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
D0871_03545	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
D0871_03550	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D0871_03565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D0871_03575	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0871_03580	COG1489	DNA binding
D0871_03585	COG1643	Atp-dependent helicase
D0871_03590	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0871_03595	COG1752	Esterase of the alpha-beta hydrolase superfamily
D0871_03600	COG1049	propionate catabolic process, 2-methylcitrate cycle
D0871_03605	COG3112	Uncharacterised protein family (UPF0231)
D0871_03615	COG0004	ammonium transporteR
D0871_03620	COG1840	ABC-type Fe3 transport system, periplasmic component
D0871_03630	COG3842	ATPase activity
D0871_03635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0871_03650	COG2971	BadF BadG BcrA BcrD
D0871_03660	COG4608	Belongs to the ABC transporter superfamily
D0871_03665	COG0444	Belongs to the ABC transporter superfamily
D0871_03670	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0871_03680	COG0747	negative chemotaxis
D0871_03685	COG2205	protein histidine kinase activity
D0871_03685	COG0784	Response regulator, receiver
D0871_03685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0871_03685	COG2198	Histidine kinase
D0871_03695	COG2813	Specifically methylates the guanine in position
D0871_03700	COG0628	permease
D0871_03705	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
D0871_03710	COG0316	Belongs to the HesB IscA family
D0871_03720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0871_03725	COG0739	heme binding
D0871_03730	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0871_03740	COG2027	D-alanyl-D-alanine carboxypeptidase
D0871_03745	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D0871_03750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0871_03755	COG1534	Rna-binding protein
D0871_03760	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
D0871_03765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D0871_03770	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D0871_03775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0871_03785	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
D0871_03800	COG0779	Required for maturation of 30S ribosomal subunits
D0871_03805	COG0195	Participates in both transcription termination and antitermination
D0871_03810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
D0871_03815	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
D0871_03820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D0871_03825	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
D0871_03830	COG1185	polyribonucleotide nucleotidyltransferase activity
D0871_03845	COG0534	Mate efflux family protein
D0871_03870	COG3153	acetyltransferase
D0871_03890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D0871_03900	COG0084	hydrolase, TatD family'
D0871_03905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0871_03910	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
D0871_03915	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
D0871_03920	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
D0871_03925	COG0813	purine-nucleoside phosphorylase activity
D0871_03935	COG0560	Phosphoserine phosphatase
D0871_03945	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
D0871_03950	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D0871_03955	COG0583	DNA-binding transcription factor activity
D0871_03965	COG1022	Amp-dependent synthetase and ligase
D0871_04005	COG0583	DNA-binding transcription factor activity
D0871_04010	COG0531	amino acid
D0871_04015	COG2731	YhcH YjgK YiaL family protein
D0871_04020	COG3250	beta-galactosidase activity
D0871_04025	COG1609	Transcriptional regulator
D0871_04035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D0871_04045	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
D0871_04050	COG2017	converts alpha-aldose to the beta-anomer
D0871_04065	COG2176	DNA-directed DNA polymerase activity
D0871_04070	COG1609	Transcriptional regulator
D0871_04075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0871_04090	COG0598	Magnesium transport protein CorA
D0871_04095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
D0871_04100	COG1349	DNA-binding transcription factor activity
D0871_04105	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D0871_04110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D0871_04125	COG2271	Major facilitator Superfamily
D0871_04130	COG0584	glycerophosphoryl diester phosphodiesterase
D0871_04135	COG2171	N-acyltransferase activity
D0871_04140	COG3141	response to X-ray
D0871_04160	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D0871_04170	COG1074	ATP-dependent DNA helicase activity
D0871_04175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D0871_04185	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
D0871_04185	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
D0871_04200	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
D0871_04205	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D0871_04210	COG2166	iron-sulfur cluster assembly
D0871_04215	COG3706	GGDEF domain
D0871_04220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D0871_04225	COG0693	protein deglycase activity
D0871_04230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
D0871_04260	COG1595	DNA-templated transcription, initiation
D0871_04280	COG3056	Lipoprotein
D0871_04285	COG2813	Specifically methylates the guanine in position
D0871_04290	COG0271	Belongs to the BolA IbaG family
D0871_04300	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D0871_04305	COG1805	sodium ion transport
D0871_04310	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D0871_04315	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D0871_04320	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
D0871_04325	COG2871	sodium ion transport
D0871_04330	COG1477	protein flavinylation
D0871_04410	COG0789	Transcriptional regulator
D0871_04415	COG4974	Belongs to the 'phage' integrase family
D0871_04425	COG1566	PFAM secretion protein HlyD family protein
D0871_04500	COG0494	nUDIX hydrolase
D0871_04525	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0871_04530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D0871_04535	COG0514	ATP-dependent DNA helicase (RecQ)
D0871_04540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0871_04555	COG0733	neurotransmitter:sodium symporter activity
D0871_04575	COG0442	prolyl-tRNA aminoacylation
D0871_04580	COG1720	tRNA m6t6A37 methyltransferase activity
D0871_04585	COG0254	rRNA binding
D0871_04595	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D0871_04600	COG1671	Belongs to the UPF0178 family
D0871_04625	COG3098	single-species biofilm formation
D0871_04630	COG0564	pseudouridine synthase activity
D0871_04640	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
D0871_04645	COG0024	Methionine aminopeptidase
D0871_04650	COG0052	Belongs to the universal ribosomal protein uS2 family
D0871_04655	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
D0871_04660	COG0528	UMP kinase activity
D0871_04665	COG0233	cytoplasmic translational termination
D0871_04670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D0871_04675	COG0575	Belongs to the CDS family
D0871_04680	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
D0871_04685	COG0750	zinc metalloprotease
D0871_04695	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
D0871_04700	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D0871_04705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0871_04710	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D0871_04715	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D0871_04720	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D0871_04725	COG0587	DNA-directed DNA polymerase activity
D0871_04730	COG0825	malonyl-CoA metabolic process
D0871_04735	COG0037	tRNA processing
D0871_04745	COG0347	Belongs to the P(II) protein family
D0871_04750	COG3021	interspecies interaction between organisms
D0871_04760	COG0741	lytic transglycosylase activity
D0871_04760	COG1388	LysM domain
D0871_04765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0871_04770	COG2226	methyltransferase
D0871_04775	COG0328	RNA-DNA hybrid ribonuclease activity
D0871_04780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D0871_04800	COG0456	acetyltransferase
D0871_04810	COG1960	acyl-CoA dehydrogenase activity
D0871_04815	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D0871_04820	COG0121	glutamine amidotransferase
D0871_04825	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D0871_04830	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
D0871_04835	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
D0871_04840	COG2233	PERMEase
D0871_04860	COG4783	chaperone-mediated protein folding
D0871_04875	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D0871_04880	COG2716	regulation of RNA biosynthetic process
D0871_04885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0871_04905	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0871_04910	COG1393	Belongs to the ArsC family
D0871_04940	COG2837	iron assimilation
D0871_04945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0871_04955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0871_04960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0871_04965	COG1334	flagellar protein FlaG
D0871_04970	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D0871_04980	COG1516	flagellar protein fliS
D0871_04990	COG4191	Histidine kinase
D0871_04995	COG2204	response regulator
D0871_05000	COG1677	Flagellar hook-basal body complex protein FliE
D0871_05010	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0871_05060	COG1987	bacterial-type flagellum assembly
D0871_05065	COG1684	flagellar biosynthetic protein fliR
D0871_05085	COG0455	bacterial-type flagellum organization
D0871_05100	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
D0871_05105	COG0643	Histidine kinase
D0871_05105	COG2198	Histidine kinase
D0871_05110	COG2201	protein-glutamate methylesterase activity
D0871_05115	COG1192	Involved in chromosome partitioning
D0871_05125	COG0835	chemotaxis
D0871_05135	COG4133	protoheme IX ABC transporter activity
D0871_05140	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0871_05145	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0871_05150	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
D0871_05155	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
D0871_05160	COG1138	Cytochrome C-type biogenesis protein
D0871_05165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
D0871_05180	COG2853	Lipoprotein
D0871_05190	COG2067	long-chain fatty acid transport protein
D0871_05210	COG0183	Belongs to the thiolase family
D0871_05215	COG1250	3-hydroxyacyl-CoA dehydrogenase
D0871_05215	COG1024	Enoyl-CoA hydratase
D0871_05230	COG2062	phosphohistidine phosphatase, SixA
D0871_05235	COG2840	Smr protein MutS2
D0871_05240	COG2890	protein-(glutamine-N5) methyltransferase activity
D0871_05245	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
D0871_05250	COG2860	membrane
D0871_05260	COG3101	peptidyl-lysine hydroxylation
D0871_05275	COG0431	NADPH-dependent FMN reductase
D0871_05280	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
D0871_05280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0871_05285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0871_05295	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D0871_05300	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D0871_05310	COG0101	tRNA pseudouridine synthase activity
D0871_05315	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D0871_05320	COG0285	dihydrofolate synthase activity
D0871_05325	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
D0871_05330	COG1286	toxin biosynthetic process
D0871_05335	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
D0871_05340	COG0583	DNA-binding transcription factor activity
D0871_05345	COG0745	RESPONSE REGULATOR receiver
D0871_05355	COG2832	Protein of unknown function (DUF454)
D0871_05360	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
D0871_05370	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
D0871_05375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D0871_05380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
D0871_05385	COG0814	amino acid
D0871_05390	COG0251	oxidation-reduction process
D0871_05395	COG3681	Belongs to the UPF0597 family
D0871_05410	COG2261	transglycosylase associated protein
D0871_05415	COG2983	Belongs to the UPF0260 family
D0871_05420	COG0668	transmembrane transport
D0871_05425	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D0871_05430	COG0346	lactoylglutathione lyase activity
D0871_05440	COG1785	Belongs to the alkaline phosphatase family
D0871_05460	COG2226	methyltransferase
D0871_05475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D0871_05480	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0871_05490	COG3139	Protein of unknown function (DUF1315)
D0871_05495	COG0252	asparaginase activity
D0871_05500	COG0616	signal peptide processing
D0871_05505	COG1902	pentaerythritol trinitrate reductase activity
D0871_05505	COG0446	pyridine nucleotide-disulphide oxidoreductase
D0871_05510	COG0778	Nitroreductase
D0871_05515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0871_05535	COG0123	including yeast histone deacetylase and acetoin utilization protein
D0871_05545	COG3083	sulfuric ester hydrolase activity
D0871_05550	COG3082	Protein of unknown function (DUF1414)
D0871_05555	COG3081	Nucleoid-associated protein
D0871_05570	COG1757	Na H antiporter
D0871_05575	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
D0871_05580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0871_05585	COG2095	MarC family integral membrane protein
D0871_05590	COG1454	alcohol dehydrogenase
D0871_05590	COG1012	belongs to the aldehyde dehydrogenase family
D0871_05610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D0871_05620	COG2056	Na+-H+ antiporter family
D0871_05625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D0871_05640	COG2885	chlorophyll binding
D0871_05650	COG0346	lactoylglutathione lyase activity
D0871_05655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D0871_05660	COG4660	Part of a membrane complex involved in electron transport
D0871_05665	COG4659	FMN binding
D0871_05670	COG4658	electron transport chain
D0871_05675	COG4656	Part of a membrane complex involved in electron transport
D0871_05680	COG2878	Part of a membrane complex involved in electron transport
D0871_05685	COG4657	Part of a membrane complex involved in electron transport
D0871_05700	COG0556	nucleotide-excision repair
D0871_05705	COG2204	response regulator
D0871_05710	COG2198	Histidine kinase
D0871_05715	COG0391	Required for morphogenesis under gluconeogenic growth conditions
D0871_05720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D0871_05725	COG0521	Mo-molybdopterin cofactor biosynthetic process
D0871_05730	COG0315	cyclic pyranopterin monophosphate synthase activity
D0871_05735	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
D0871_05740	COG0314	molybdopterin synthase activity
D0871_05750	COG0601	transmembrane transport
D0871_05755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0871_05760	COG0444	Belongs to the ABC transporter superfamily
D0871_05770	COG0435	Glutathione S-transferase
D0871_05780	COG3174	membrane
D0871_05785	COG0280	phosphate acetyltransferase
D0871_05785	COG0857	belongs to the CobB CobQ family
D0871_05790	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D0871_05795	COG3092	negative regulation of chromosome organization
D0871_05805	COG4120	Belongs to the binding-protein-dependent transport system permease family
D0871_05810	COG1122	ATPase activity
D0871_05815	COG0366	Alpha amylase catalytic
D0871_05820	COG3706	GGDEF domain
D0871_05820	COG0745	RESPONSE REGULATOR receiver
D0871_05825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D0871_05830	COG3012	SEC-C Motif Domain Protein
D0871_05830	COG3318	Belongs to the UPF0149 family
D0871_05835	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
D0871_05840	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D0871_05845	COG2186	Transcriptional regulator
D0871_05855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0871_05855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0871_05860	COG0489	protein tyrosine kinase activity
D0871_05865	COG0572	uridine kinase
D0871_05875	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
D0871_05880	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D0871_05885	COG0659	secondary active sulfate transmembrane transporter activity
D0871_05895	COG1530	ribonuclease E activity
D0871_05910	COG0564	pseudouridine synthase activity
D0871_05915	COG0424	maF-like protein
D0871_05920	COG1399	metal-binding, possibly nucleic acid-binding protein
D0871_05930	COG0416	fatty acid biosynthetic process
D0871_05935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0871_05965	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D0871_05970	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
D0871_05980	COG0084	hydrolase, TatD family'
D0871_05985	COG1263	PTS System
D0871_05985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0871_06005	COG0733	neurotransmitter:sodium symporter activity
D0871_06020	COG4667	esterase of the alpha-beta hydrolase superfamily
D0871_06025	COG0469	pyruvate kinase activity
D0871_06030	COG1940	carbohydrate kinase activity
D0871_06035	COG0784	Response regulator, receiver
D0871_06035	COG0835	chemotaxis
D0871_06040	COG0587	DNA-directed DNA polymerase activity
D0871_06055	COG1028	Short-chain dehydrogenase reductase Sdr
D0871_06060	COG0616	signal peptide processing
D0871_06065	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
D0871_06070	COG0539	negative regulation of cytoplasmic translation
D0871_06080	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
D0871_06085	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
D0871_06090	COG0284	orotidine-5'-phosphate decarboxylase activity
D0871_06095	COG4166	transmembrane transport
D0871_06110	COG0463	Glycosyl transferase, family 2
D0871_06120	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
D0871_06130	COG3008	intermembrane lipid transfer
D0871_06130	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D0871_06135	COG2995	paraquat-inducible protein a
D0871_06140	COG3258	Cytochrome c
D0871_06145	COG2863	cytochrome
D0871_06185	COG4232	protein-disulfide reductase activity
D0871_06190	COG3118	belongs to the thioredoxin family
D0871_06215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0871_06225	COG0577	efflux transmembrane transporter activity
D0871_06225	COG1136	(ABC) transporter
D0871_06235	COG0577	efflux transmembrane transporter activity
D0871_06235	COG1136	(ABC) transporter
D0871_06240	COG1335	isochorismatase
D0871_06255	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0871_06290	COG5002	protein histidine kinase activity
D0871_06290	COG3850	Histidine kinase
D0871_06295	COG0745	RESPONSE REGULATOR receiver
D0871_06305	COG0840	transmembrane signaling receptor activity
D0871_06310	COG1032	radical SAM domain protein
D0871_06315	COG4251	negative regulation of phosphorylation
D0871_06315	COG5001	Diguanylate cyclase
D0871_06315	COG3706	GGDEF domain
D0871_06315	COG2203	Gaf domain
D0871_06330	COG0583	DNA-binding transcription factor activity
D0871_06340	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
D0871_06350	COG2350	Protein conserved in bacteria
D0871_06355	COG1607	acyl-coa hydrolase
D0871_06360	COG2917	probably involved in intracellular septation
D0871_06380	COG1301	dicarboxylic acid transport
D0871_06390	COG0318	PFAM AMP-dependent synthetase and ligase
D0871_06395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0871_06405	COG0159	tryptophan synthase activity
D0871_06410	COG0133	tryptophan synthase activity
D0871_06415	COG0135	phosphoribosylanthranilate isomerase activity
D0871_06415	COG0134	indole-3-glycerol-phosphate synthase activity
D0871_06420	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D0871_06425	COG0512	Glutamine amidotransferase of anthranilate synthase
D0871_06430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0871_06440	COG0613	PHP domain protein
D0871_06445	COG0009	L-threonylcarbamoyladenylate synthase
D0871_06455	COG1187	pseudouridine synthase activity
D0871_06465	COG3099	Belongs to the UPF0263 family
D0871_06470	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
D0871_06480	COG0417	DNA replication proofreading
D0871_06485	COG2197	response regulator
D0871_06490	COG0322	excinuclease ABC activity
D0871_06530	COG0019	diaminopimelate decarboxylase activity
D0871_06555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0871_06560	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D0871_06565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0871_06585	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
D0871_06595	COG0437	4 iron, 4 sulfur cluster binding
D0871_06600	COG3301	Polysulphide reductase, NrfD
D0871_06605	COG1138	Cytochrome C-type biogenesis protein
D0871_06615	COG4235	cytochrome complex assembly
D0871_06615	COG3088	subunit of a heme lyase
D0871_06625	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0871_06650	COG2989	Protein conserved in bacteria
D0871_06655	COG3108	Peptidase M15
D0871_06660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D0871_06675	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
D0871_06700	COG1846	Transcriptional regulator
D0871_06705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0871_06710	COG0840	transmembrane signaling receptor activity
D0871_06730	COG1448	Aminotransferase
D0871_06755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0871_06765	COG0017	Asparaginyl-tRNA synthetase
D0871_06770	COG0840	transmembrane signaling receptor activity
D0871_06775	COG0720	synthase
D0871_06785	COG2200	EAL domain
D0871_06790	COG1760	l-serine dehydratase
D0871_06795	COG0814	amino acid
D0871_06800	COG0494	nUDIX hydrolase
D0871_06810	COG0784	Response regulator, receiver
D0871_06810	COG2205	protein histidine kinase activity
D0871_06815	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D0871_06835	COG3106	COG3106 Predicted ATPase
D0871_06840	COG3768	UPF0283 membrane protein
D0871_06850	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0871_06975	COG1335	isochorismatase
D0871_07245	COG0384	phenazine biosynthesis protein PhzF
D0871_07280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D0871_07475	COG2026	Addiction module toxin, RelE StbE family
D0871_07765	COG0346	lactoylglutathione lyase activity
D0871_07890	COG4735	regulation of single-species biofilm formation
D0871_07950	COG2026	Addiction module toxin, RelE StbE family
D0871_08000	COG1757	Na H antiporter
D0871_08005	COG0174	glutamine synthetase
D0871_08015	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
D0871_08020	COG1396	sequence-specific DNA binding
D0871_08020	COG1917	Cupin 2, conserved barrel domain protein
D0871_08025	COG1012	belongs to the aldehyde dehydrogenase family
D0871_08030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0871_08040	COG2957	Belongs to the agmatine deiminase family
D0871_08045	COG1012	belongs to the aldehyde dehydrogenase family
D0871_08050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D0871_08055	COG1227	inorganic diphosphatase activity
D0871_08065	COG2771	luxR family
D0871_08065	COG2200	EAL domain
D0871_08080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
D0871_08095	COG1846	Transcriptional regulator
D0871_08100	COG2315	Protein conserved in bacteria
D0871_08120	COG0110	maltose O-acetyltransferase activity
D0871_08150	COG3063	Type IV pilus biogenesis stability protein PilW
D0871_08155	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
D0871_08170	COG0531	amino acid
D0871_08180	COG1560	Kdo2-lipid A biosynthetic process
D0871_08195	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
D0871_08300	COG2204	response regulator
D0871_08340	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D0871_08380	COG2199	diguanylate cyclase activity
D0871_08425	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
D0871_08430	COG1280	lysine exporter protein (LysE YggA)
D0871_08440	COG1115	amino acid carrier protein
D0871_08465	COG1368	sulfuric ester hydrolase activity
D0871_08470	COG0642	Histidine kinase
D0871_08475	COG0745	RESPONSE REGULATOR receiver
D0871_08485	COG1028	Short-chain dehydrogenase reductase Sdr
D0871_08510	COG4176	ABC-type proline glycine betaine transport system permease component
D0871_08530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0871_08535	COG0456	acetyltransferase
D0871_08540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D0871_08545	COG0662	Cupin 2, conserved barrel domain protein
D0871_08550	COG0527	aspartate kinase activity
D0871_08555	COG1858	cytochrome C peroxidase
D0871_08570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0871_08585	COG3290	protein histidine kinase activity
D0871_08590	COG4565	transcriptional regulatory protein
D0871_08605	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
D0871_08610	COG0363	glucosamine-6-phosphate deaminase activity
D0871_08615	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
D0871_08640	COG3284	Transcriptional regulator
D0871_08645	COG1012	belongs to the aldehyde dehydrogenase family
D0871_08715	COG4669	(LipO)protein
D0871_08735	COG3177	Filamentation induced by cAMP protein fic
D0871_08775	COG1073	alpha beta
D0871_08780	COG1073	alpha beta
D0871_08790	COG4792	protein secretion
D0871_08795	COG4791	protein targeting
D0871_08800	COG4794	Type iii secretion
D0871_08805	COG4790	Type iii secretion
D0871_08810	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0871_08875	COG0457	Tetratricopeptide repeat
D0871_08925	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
D0871_08930	COG0372	Belongs to the citrate synthase family
D0871_08945	COG2828	Protein conserved in bacteria
D0871_08970	COG0561	phosphatase activity
D0871_08975	COG0602	queuosine metabolic process
D0871_08980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D0871_08985	COG3706	GGDEF domain
D0871_09030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D0871_09035	COG0840	transmembrane signaling receptor activity
D0871_09040	COG1254	Belongs to the acylphosphatase family
D0871_09045	COG2920	part of a sulfur-relay system
D0871_09055	COG0670	Belongs to the BI1 family
D0871_09060	COG1126	abc transporter atp-binding protein
D0871_09065	COG0765	amino acid transport
D0871_09070	COG4597	amino acid ABC transporter
D0871_09075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0871_09095	COG1666	GTP binding
D0871_09100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D0871_09120	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
D0871_09120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0871_09130	COG3008	intermembrane lipid transfer
D0871_09135	COG2995	paraquat-inducible protein a
D0871_09140	COG1132	(ABC) transporter
D0871_09145	COG1956	GAF domain-containing protein
D0871_09150	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
D0871_09165	COG0308	aminopeptidase N
D0871_09175	COG2902	Dehydrogenase
D0871_09180	COG0167	dihydroorotate dehydrogenase activity
D0871_09195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
D0871_09195	COG0116	Belongs to the methyltransferase superfamily
D0871_09220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0871_09225	COG1067	ATP-dependent peptidase activity
D0871_09230	COG3120	sequence-specific DNA binding
D0871_09320	COG4128	Pfam Zonular occludens toxin
D0871_09385	COG3278	Belongs to the heme-copper respiratory oxidase family
D0871_09400	COG2010	Cytochrome c
D0871_09410	COG2217	Heavy metal translocating P-type atpase
D0871_09425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D0871_09430	COG0589	response to stress
D0871_09440	COG0037	tRNA processing
D0871_09460	COG3842	ATPase activity
D0871_09465	COG1176	ABC-type spermidine putrescine transport system, permease component I
D0871_09470	COG1177	transmembrane transport
D0871_09475	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D0871_09480	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D0871_09485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D0871_09495	COG0004	ammonium transporteR
D0871_09520	COG0437	4 iron, 4 sulfur cluster binding
D0871_09525	COG0243	molybdopterin cofactor binding
D0871_09525	COG3383	formate dehydrogenase (NAD+) activity
D0871_09535	COG3381	protein complex oligomerization
D0871_09560	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D0871_09565	COG0488	(ABC) transporter
D0871_09575	COG4191	Histidine kinase
D0871_09580	COG2204	response regulator
D0871_09600	COG3842	ATPase activity
D0871_09605	COG0746	molybdenum cofactor guanylyltransferase activity
D0871_09610	COG0303	'Molybdopterin
D0871_09620	COG1940	carbohydrate kinase activity
D0871_09660	COG0840	transmembrane signaling receptor activity
D0871_09660	COG3290	protein histidine kinase activity
D0871_09665	COG0791	NLP P60 protein
D0871_09675	COG3706	GGDEF domain
D0871_09680	COG2201	protein-glutamate methylesterase activity
D0871_09695	COG0307	riboflavin synthase, alpha
D0871_09700	COG0534	Mate efflux family protein
D0871_09710	COG1793	dna ligase
D0871_09745	COG2204	response regulator
D0871_09790	COG0438	transferase activity, transferring glycosyl groups
D0871_09795	COG1215	transferase activity, transferring glycosyl groups
D0871_09800	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D0871_09810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0871_09825	COG1643	Atp-dependent helicase
D0871_09830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D0871_09835	COG2221	Nitrite and sulphite reductase 4Fe-4S
D0871_09835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D0871_09845	COG3302	dmso reductase anchor subunit
D0871_09850	COG0437	4 iron, 4 sulfur cluster binding
D0871_09855	COG0243	molybdopterin cofactor binding
D0871_09885	COG3706	GGDEF domain
D0871_09895	COG0443	Heat shock 70 kDa protein
D0871_09900	COG0443	Heat shock 70 kDa protein
D0871_09930	COG1132	(ABC) transporter
D0871_09935	COG1132	(ABC) transporter
D0871_09960	COG0814	amino acid
D0871_09975	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
D0871_10045	COG1522	sequence-specific DNA binding
D0871_10080	COG0515	serine threonine protein kinase
D0871_10105	COG3501	Rhs element vgr protein
D0871_10120	COG2204	response regulator
D0871_10145	COG0739	heme binding
D0871_10155	COG0861	Integral membrane protein TerC family
D0871_10165	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D0871_10170	COG1328	CTP reductase activity
D0871_10175	COG1280	lysine exporter protein (LysE YggA)
D0871_10185	COG3300	MHYT domain
D0871_10185	COG5001	Diguanylate cyclase
D0871_10195	COG4191	Histidine kinase
D0871_10195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0871_10200	COG0471	metal ion transport
D0871_10235	COG0583	DNA-binding transcription factor activity
D0871_10240	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
D0871_10300	COG0625	glutathione transferase activity
D0871_10310	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
D0871_10325	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0871_10335	COG0601	transmembrane transport
D0871_10340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0871_10345	COG0444	Belongs to the ABC transporter superfamily
D0871_10365	COG3291	Pkd domain containing protein
D0871_10380	COG1177	transmembrane transport
D0871_10385	COG1176	ABC-type spermidine putrescine transport system, permease component I
D0871_10390	COG3842	ATPase activity
D0871_10395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D0871_10400	COG2423	ornithine cyclodeaminase activity
D0871_10420	COG3938	Belongs to the proline racemase family
D0871_10450	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
D0871_10455	COG1451	nucleotide metabolic process
D0871_10460	COG3475	LICD family
D0871_10465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D0871_10470	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
D0871_10490	COG0583	DNA-binding transcription factor activity
D0871_10510	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
D0871_10515	COG4139	cobalamin transport
D0871_10520	COG2988	succinylglutamate desuccinylase activity
D0871_10545	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
D0871_10550	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D0871_10555	COG0702	epimerase
D0871_10565	COG2925	Exonuclease
D0871_10570	COG1380	Effector of murein hydrolase LrgA
D0871_10575	COG1346	cytolysis
D0871_10580	COG0295	cytidine deaminase activity
D0871_10585	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
D0871_10590	COG0500	methyltransferase
D0871_10600	COG0776	regulation of translation
D0871_10615	COG0072	phenylalanine-tRNA ligase activity
D0871_10615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D0871_10620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
D0871_10625	COG3706	GGDEF domain
D0871_10655	COG0393	Putative heavy-metal-binding
D0871_10665	COG0291	Belongs to the bacterial ribosomal protein bL35 family
D0871_10675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
D0871_10690	COG2188	Transcriptional regulator
D0871_10695	COG1228	amidohydrolase
D0871_10700	COG0010	Belongs to the arginase family
D0871_10705	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
D0871_10710	COG2986	histidine ammonia-lyase
D0871_10725	COG0247	lactate metabolic process
D0871_10725	COG0277	FAD linked oxidase domain protein
D0871_10760	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
D0871_10775	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
D0871_10780	COG1643	Atp-dependent helicase
D0871_10785	COG0281	malic enzyme
D0871_10790	COG2949	membrane
D0871_10795	COG0471	metal ion transport
D0871_10800	COG3706	GGDEF domain
D0871_10800	COG0745	RESPONSE REGULATOR receiver
D0871_10820	COG0492	ferredoxin-NADP+ reductase activity
D0871_10825	COG4988	ABC transporter
D0871_10830	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
D0871_10835	COG3048	D-serine ammonia-lyase activity
D0871_10840	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
D0871_10850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0871_10850	COG4191	Histidine kinase
D0871_10865	COG3070	regulator of competence-specific genes
D0871_10885	COG2431	L-lysine efflux transmembrane transporter activity
D0871_10895	COG0076	glutamate decarboxylase activity
D0871_10900	COG1737	Transcriptional regulator
D0871_10915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D0871_10920	COG2985	domain, Protein
D0871_10920	COG3273	potassium ion transport
D0871_10925	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D0871_10940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D0871_10955	COG4181	ATPase activity
D0871_10960	COG0534	Mate efflux family protein
D0871_10965	COG0702	epimerase
D0871_10970	COG3005	denitrification pathway
D0871_11000	COG2814	Major facilitator Superfamily
D0871_11005	COG1187	pseudouridine synthase activity
D0871_11010	COG1061	Type III restriction enzyme res subunit
D0871_11020	COG0745	RESPONSE REGULATOR receiver
D0871_11025	COG2205	protein histidine kinase activity
D0871_11030	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
D0871_11060	COG3313	Fe-S protein
D0871_11085	COG0493	'glutamate synthase
D0871_11095	COG0398	Pfam SNARE associated Golgi protein
D0871_11100	COG4134	Bacterial extracellular solute-binding protein
D0871_11105	COG4135	transport system, permease component
D0871_11110	COG4136	ATPase activity
D0871_11115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D0871_11130	COG3604	Transcriptional regulator
D0871_11135	COG1151	hydroxylamine reductase activity
D0871_11140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0871_11150	COG0564	pseudouridine synthase activity
D0871_11160	COG0733	neurotransmitter:sodium symporter activity
D0871_11170	COG0626	cystathionine gamma-synthase activity
D0871_11175	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
D0871_11180	COG5380	lipid catabolic process
D0871_11185	COG2818	Glycosylase
D0871_11200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0871_11205	COG1983	PspC domain protein
D0871_11215	COG1842	Phage shock protein A
D0871_11220	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
D0871_11230	COG4168	peptide transport system, permease
D0871_11235	COG4171	peptide transport system, permease
D0871_11245	COG4172	Belongs to the ABC transporter superfamily
D0871_11255	COG1227	inorganic diphosphatase activity
D0871_11270	COG0243	molybdopterin cofactor binding
D0871_11275	COG3005	denitrification pathway
D0871_11280	COG4459	periplasmic nitrate reductase
D0871_11285	COG0390	transport system, permease component
D0871_11295	COG2116	formate transmembrane transporter activity
D0871_11320	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D0871_11325	COG1435	thymidine kinase activity
D0871_11330	COG0215	cysteine-tRNA ligase activity
D0871_11335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D0871_11340	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D0871_11345	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
D0871_11355	COG3012	SEC-C Motif Domain Protein
D0871_11360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D0871_11360	COG0140	phosphoribosyl-ATP diphosphatase activity
D0871_11365	COG0107	imidazoleglycerol-phosphate synthase activity
D0871_11370	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
D0871_11375	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D0871_11380	COG0131	Imidazoleglycerol-phosphate dehydratase
D0871_11380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D0871_11385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
D0871_11390	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D0871_11395	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D0871_11410	COG1757	Na H antiporter
D0871_11420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0871_11430	COG0482	sulfurtransferase activity
D0871_11435	COG2915	High frequency lysogenization protein hflD homolog
D0871_11440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D0871_11465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
D0871_11480	COG0300	oxidoreductase activity
D0871_11490	COG0501	Belongs to the peptidase M48B family
D0871_11500	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
D0871_11510	COG0156	8-amino-7-oxononanoate synthase activity
D0871_11515	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
D0871_11525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D0871_11540	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
D0871_11545	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D0871_11550	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D0871_11555	COG1674	ftsk spoiiie
D0871_11565	COG0686	Belongs to the AlaDH PNT family
D0871_11575	COG0583	DNA-binding transcription factor activity
D0871_11590	COG3568	Endonuclease Exonuclease Phosphatase
D0871_11620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0871_11625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0871_11640	COG0840	transmembrane signaling receptor activity
D0871_11670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
D0871_11745	COG4245	von Willebrand factor, type A
D0871_11775	COG0582	viral genome integration into host DNA
D0871_11810	COG0784	Response regulator, receiver
D0871_11810	COG5002	protein histidine kinase activity
D0871_11820	COG0754	glutathionylspermidine amidase activity
D0871_11830	COG3766	membrane
D0871_11840	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D0871_11845	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
D0871_11850	COG2885	chlorophyll binding
D0871_11855	COG0823	Involved in the tonB-independent uptake of proteins
D0871_11870	COG0811	peptide transport
D0871_11875	COG0824	Thioesterase
D0871_11885	COG4890	Cyd operon protein YbgT
D0871_11890	COG1294	oxidase, subunit
D0871_11895	COG1271	oxidase subunit
D0871_11900	COG2255	four-way junction helicase activity
D0871_11905	COG0632	four-way junction helicase activity
D0871_11910	COG0840	transmembrane signaling receptor activity
D0871_11915	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
D0871_11920	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
D0871_11925	COG1801	Protein of unknown function DUF72
D0871_11930	COG4106	trans-aconitate 2-methyltransferase activity
D0871_11935	COG0500	methyltransferase
D0871_11945	COG4067	protein conserved in archaea
D0871_11945	COG0189	ligase activity
D0871_11965	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D0871_11970	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
D0871_11975	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
D0871_11980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0871_11985	COG1434	Gram-negative-bacterium-type cell wall biogenesis
D0871_11990	COG0745	RESPONSE REGULATOR receiver
D0871_11995	COG3381	protein complex oligomerization
D0871_12000	COG1609	Transcriptional regulator
D0871_12005	COG3070	regulator of competence-specific genes
D0871_12025	COG0297	glycogen (starch) synthase activity
D0871_12030	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0871_12035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0871_12045	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D0871_12055	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
D0871_12060	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
D0871_12065	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
D0871_12075	COG0542	response to heat
D0871_12080	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D0871_12085	COG1278	Cold shock
D0871_12095	COG1187	pseudouridine synthase activity
D0871_12100	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
D0871_12110	COG1199	ATP-dependent helicase activity
D0871_12115	COG0730	response to heat
D0871_12120	COG3923	Primosomal replication protein n
D0871_12130	COG0708	Exodeoxyribonuclease III
D0871_12145	COG4215	(ABC) transporter
D0871_12175	COG1882	Formate acetyltransferase
D0871_12185	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D0871_12195	COG3013	Belongs to the UPF0304 family
D0871_12205	COG2766	serine protein kinase
D0871_12210	COG2718	Belongs to the UPF0229 family
D0871_12215	COG2719	SpoVR family
D0871_12220	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
D0871_12230	COG1663	tetraacyldisaccharide 4'-kinase activity
D0871_12235	COG1132	(ABC) transporter
D0871_12240	COG2333	competence protein COMEC
D0871_12240	COG0658	competence protein
D0871_12250	COG4591	ABC-type transport system involved in lipoprotein release permease component
D0871_12255	COG1136	(ABC) transporter
D0871_12260	COG4591	ABC-type transport system involved in lipoprotein release permease component
D0871_12270	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D0871_12285	COG1252	NADH dehydrogenase
D0871_12295	COG3150	esterase
D0871_12320	COG0537	adenosine 5'-monophosphoramidase activity
D0871_12350	COG0517	IMP dehydrogenase activity
D0871_12350	COG0516	GMP reductase activity
D0871_12360	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
D0871_12365	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D0871_12370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0871_12380	COG2199	diguanylate cyclase activity
D0871_12395	COG3126	Type III secretion system lipoprotein chaperone (YscW)
D0871_12400	COG1946	Acyl-CoA thioesterase
D0871_12410	COG1522	sequence-specific DNA binding
D0871_12440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0871_12445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0871_12490	COG0477	Major facilitator Superfamily
D0871_12495	COG2855	membrane
D0871_12510	COG1441	menaquinone biosynthetic process
D0871_12515	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
D0871_12520	COG0596	Alpha beta hydrolase
D0871_12525	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
D0871_12530	COG1169	isochorismate synthase
D0871_12535	COG0436	Aminotransferase
D0871_12540	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
D0871_12545	COG0232	Belongs to the dGTPase family. Type 2 subfamily
D0871_12560	COG1555	photosystem II stabilization
D0871_12565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0871_12570	COG0776	regulation of translation
D0871_12575	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
D0871_12580	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
D0871_12590	COG0544	peptidyl-prolyl cis-trans isomerase activity
D0871_12600	COG2204	response regulator
D0871_12610	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
D0871_12615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
D0871_12620	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
D0871_12625	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
D0871_12645	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0871_12650	COG0569	domain protein
D0871_12655	COG0513	Belongs to the DEAD box helicase family
D0871_12660	COG1253	flavin adenine dinucleotide binding
D0871_12695	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0871_12700	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D0871_12715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0871_12720	COG1216	Glycosyl transferase, family 2
D0871_12725	COG2986	histidine ammonia-lyase
D0871_12750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D0871_12755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
D0871_12760	COG1028	Short-chain dehydrogenase reductase Sdr
D0871_12780	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
D0871_12785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0871_12790	COG0583	DNA-binding transcription factor activity
D0871_12795	COG2951	lytic endotransglycosylase activity
D0871_12800	COG3100	YcgL domain-containing protein
D0871_12805	COG0850	regulation of cytokinetic process
D0871_12810	COG2894	cell division
D0871_12815	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
D0871_12820	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
D0871_12825	COG0318	PFAM AMP-dependent synthetase and ligase
D0871_12830	COG2267	carboxylic ester hydrolase activity
D0871_12845	COG1214	PFAM Peptidase M22, glycoprotease
D0871_12850	COG1199	ATP-dependent helicase activity
D0871_12855	COG0788	formyltetrahydrofolate deformylase activity
D0871_12860	COG3102	Protein conserved in bacteria
D0871_12870	COG0018	arginyl-trna synthetase
D0871_12890	COG1918	ferrous iron import across plasma membrane
D0871_12905	COG4977	sequence-specific DNA binding
D0871_12910	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
D0871_12915	COG1121	(ABC) transporter
D0871_12920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0871_12930	COG0045	succinate-CoA ligase (ADP-forming) activity
D0871_12935	COG0508	dehydrogenase complex catalyzes the overall conversion of
D0871_12940	COG0567	Dehydrogenase, E1 component
D0871_12945	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D0871_12950	COG1053	succinate dehydrogenase
D0871_12955	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D0871_12960	COG2009	succinate dehydrogenase
D0871_12970	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D0871_12980	COG0033	Phosphoglucomutase
D0871_12985	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
D0871_12990	COG0596	Alpha beta hydrolase
D0871_13000	COG0716	FMN binding
D0871_13010	COG0735	belongs to the Fur family
D0871_13015	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D0871_13020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0871_13020	COG1263	PTS System
D0871_13020	COG2190	(PTS) system
D0871_13030	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
D0871_13035	COG1940	carbohydrate kinase activity
D0871_13035	COG1846	Transcriptional regulator
D0871_13040	COG4651	solute:proton antiporter activity
D0871_13040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D0871_13045	COG0367	asparagine synthase
D0871_13050	COG0250	Participates in transcription elongation, termination and antitermination
D0871_13055	COG3104	oligopeptide transport
D0871_13060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
D0871_13065	COG0563	adenylate kinase activity
D0871_13070	COG0326	Molecular chaperone. Has ATPase activity
D0871_13075	COG3710	Transcriptional regulator
D0871_13095	COG0622	Phosphoesterase
D0871_13125	COG1090	epimerase
D0871_13130	COG0300	oxidoreductase activity
D0871_13140	COG3118	belongs to the thioredoxin family
D0871_13145	COG0330	HflC and HflK could
D0871_13175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
D0871_13180	COG3115	cell septum assembly
D0871_13185	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
D0871_13190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D0871_13200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0871_13205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D0871_13210	COG2190	(PTS) system
D0871_13220	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0871_13225	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0871_13235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0871_13245	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0871_13255	COG1705	Flagellar rod assembly protein muramidase FlgJ
D0871_13255	COG3951	Flagellar rod assembly protein muramidase FlgJ
D0871_13260	COG1706	bacterial-type flagellum-dependent cell motility
D0871_13265	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
D0871_13270	COG4786	Flagellar basal body rod
D0871_13275	COG4787	bacterial-type flagellum-dependent cell motility
D0871_13285	COG1749	Flagellar hook protein flgE
D0871_13290	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D0871_13295	COG1558	bacterial-type flagellum-dependent cell motility
D0871_13300	COG1815	bacterial-type flagellum-dependent cell motility
D0871_13305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
D0871_13310	COG0835	chemotaxis
D0871_13310	COG0784	Response regulator, receiver
D0871_13370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D0871_13375	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
D0871_13390	COG2217	Heavy metal translocating P-type atpase
D0871_13390	COG2608	mercury ion transmembrane transporter activity
D0871_13430	COG2840	Smr protein MutS2
D0871_13435	COG1187	pseudouridine synthase activity
D0871_13445	COG0737	Belongs to the 5'-nucleotidase family
D0871_13450	COG2877	3-deoxy-8-phosphooctulonate synthase activity
D0871_13455	COG2912	Transglutaminase-like superfamily
D0871_13460	COG3094	Invasion gene expression up-regulator, SirB
D0871_13465	COG2890	protein-(glutamine-N5) methyltransferase activity
D0871_13470	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
D0871_13475	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
D0871_13480	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
D0871_13485	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
D0871_13490	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D0871_13495	COG0193	aminoacyl-tRNA hydrolase activity
D0871_13500	COG0012	GTP binding
D0871_13615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D0871_13625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
D0871_13630	COG1702	phosphate starvation-inducible protein PhoH
D0871_13635	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
D0871_13640	COG4535	Mg2 and Co2 transporter CorC
D0871_13645	COG0815	Transfers the fatty acyl group on membrane lipoproteins
D0871_13650	COG2888	peptidyl-tyrosine sulfation
D0871_13655	COG0495	leucyl-tRNA aminoacylation
D0871_13660	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
D0871_13665	COG1466	dna polymerase III delta subunit
D0871_13670	COG0799	negative regulation of ribosome biogenesis
D0871_13675	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
D0871_13680	COG0768	penicillin binding
D0871_13685	COG0772	Belongs to the SEDS family
D0871_13690	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D0871_13695	COG1686	Belongs to the peptidase S11 family
D0871_13700	COG2921	Belongs to the UPF0250 family
D0871_13705	COG0321	lipoyl(octanoyl) transferase activity
D0871_13710	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D0871_13715	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D0871_13735	COG0366	Alpha amylase catalytic
D0871_13740	COG1263	PTS System
D0871_13740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0871_13750	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
D0871_13760	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D0871_13765	COG2011	ABC-type metal ion transport system permease component
D0871_13770	COG1464	Belongs to the NlpA lipoprotein family
D0871_13775	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
D0871_13785	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D0871_13785	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
D0871_13795	COG3706	GGDEF domain
D0871_13800	COG1611	Belongs to the LOG family
D0871_13805	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0871_13815	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
D0871_13820	COG2363	Small membrane protein
D0871_13830	COG0583	DNA-binding transcription factor activity
D0871_13835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0871_13835	COG0301	tRNA thio-modification
D0871_13840	COG2885	chlorophyll binding
D0871_13845	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D0871_13850	COG1722	exodeoxyribonuclease VII activity
D0871_13855	COG0142	geranyltranstransferase activity
D0871_13860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
D0871_13865	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D0871_13870	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D0871_13875	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0871_13895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0871_13895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0871_13900	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
D0871_13905	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
D0871_13910	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
D0871_13925	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
D0871_13930	COG2252	PERMEase
D0871_13935	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0871_13960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D0871_13960	COG0047	phosphoribosylformylglycinamidine synthase activity
D0871_13965	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
D0871_13975	COG0590	tRNA wobble adenosine to inosine editing
D0871_13980	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
D0871_14005	COG4969	Belongs to the N-Me-Phe pilin family
D0871_14020	COG0484	heat shock protein binding
D0871_14025	COG0443	Heat shock 70 kDa protein
D0871_14035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D0871_14040	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D0871_14050	COG0497	DNA recombination
D0871_14055	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0871_14060	COG2914	Belongs to the UPF0125 (RnfH) family
D0871_14065	COG2867	negative regulation of translational initiation
D0871_14070	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
D0871_14080	COG0582	viral genome integration into host DNA
D0871_14130	COG0583	DNA-binding transcription factor activity
D0871_14135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D0871_14135	COG3153	acetyltransferase
D0871_14155	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
D0871_14160	COG2873	o-acetylhomoserine
D0871_14195	COG1115	amino acid carrier protein
D0871_14205	COG1584	GPR1 FUN34 yaaH family protein
D0871_14215	COG1757	Na H antiporter
D0871_14220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D0871_14220	COG0519	Catalyzes the synthesis of GMP from XMP
D0871_14225	COG0516	GMP reductase activity
D0871_14225	COG0517	IMP dehydrogenase activity
D0871_14230	COG1570	exodeoxyribonuclease VII activity
D0871_14245	COG1160	GTP binding
D0871_14250	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0871_14255	COG2976	Protein conserved in bacteria
D0871_14260	COG0124	histidyl-tRNA synthetase
D0871_14265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
D0871_14280	COG0820	rRNA (adenine-C2-)-methyltransferase activity
D0871_14285	COG0105	UTP biosynthetic process
D0871_14290	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
D0871_14295	COG2975	iron-sulfur cluster assembly
D0871_14300	COG0633	Ferredoxin
D0871_14305	COG0443	Heat shock 70 kDa protein
D0871_14310	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D0871_14320	COG0822	iron-sulfur transferase activity
D0871_14325	COG1104	cysteine desulfurase activity
D0871_14340	COG0483	inositol monophosphate 1-phosphatase activity
D0871_14350	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0871_14355	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0871_14360	COG1862	Preprotein translocase
D0871_14365	COG0343	queuine tRNA-ribosyltransferase activity
D0871_14370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
D0871_14385	COG0517	IMP dehydrogenase activity
D0871_14395	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D0871_14405	COG0583	DNA-binding transcription factor activity
D0871_14410	COG0450	alkyl hydroperoxide reductase
D0871_14420	COG3142	Participates in the control of copper homeostasis
D0871_14430	COG0704	Plays a role in the regulation of phosphate uptake
D0871_14435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0871_14440	COG0581	inorganic phosphate transmembrane transporter activity
D0871_14450	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
D0871_14455	COG0248	Ppx GppA phosphatase
D0871_14465	COG5002	protein histidine kinase activity
D0871_14470	COG0745	RESPONSE REGULATOR receiver
D0871_14480	COG2974	May be involved in recombination
D0871_14490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D0871_14550	COG0542	response to heat
D0871_14560	COG0564	pseudouridine synthase activity
D0871_14565	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0871_14570	COG0741	lytic transglycosylase activity
D0871_14575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
D0871_14580	COG0077	Prephenate dehydratase
D0871_14580	COG1605	Chorismate mutase
D0871_14585	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
D0871_14590	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
D0871_14600	COG0488	(ABC) transporter
D0871_14615	COG0739	heme binding
D0871_14620	COG1605	Chorismate mutase
D0871_14620	COG0287	Prephenate dehydrogenase
D0871_14625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D0871_14630	COG1472	Belongs to the glycosyl hydrolase 3 family
D0871_14635	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
D0871_14640	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D0871_14655	COG1966	Carbon starvation protein
D0871_14660	COG3275	phosphorelay sensor kinase activity
D0871_14665	COG3279	Response regulator of the LytR AlgR family
D0871_14670	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
D0871_14675	COG1047	Peptidyl-prolyl cis-trans
D0871_14680	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
D0871_14685	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D0871_14690	COG0196	riboflavin kinase activity
D0871_14695	COG0728	peptidoglycan biosynthetic process
D0871_14700	COG0268	Binds directly to 16S ribosomal RNA
D0871_14710	COG0640	Transcriptional regulator
D0871_14720	COG0583	DNA-binding transcription factor activity
D0871_14725	COG1283	sodium-dependent phosphate transmembrane transporter activity
D0871_14735	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
D0871_14740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
D0871_14745	COG0730	response to heat
D0871_14755	COG0494	nUDIX hydrolase
D0871_14765	COG3066	DNA modification
D0871_14775	COG0667	Aldo Keto reductase
D0871_14790	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
D0871_14800	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D0871_14805	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0871_14815	COG0716	FMN binding
D0871_14825	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
D0871_14830	COG0513	Belongs to the DEAD box helicase family
D0871_14835	COG3022	response to hydroperoxide
D0871_14840	COG1115	amino acid carrier protein
D0871_14855	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
D0871_14865	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
D0871_14870	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
D0871_14875	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D0871_14880	COG0083	homoserine kinase activity
D0871_14895	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D0871_14910	COG0745	RESPONSE REGULATOR receiver
D0871_14920	COG5002	protein histidine kinase activity
D0871_14920	COG2198	Histidine kinase
D0871_14920	COG0784	Response regulator, receiver
D0871_14925	COG2203	Gaf domain
D0871_14925	COG3706	GGDEF domain
D0871_14925	COG4251	negative regulation of phosphorylation
D0871_14925	COG5001	Diguanylate cyclase
D0871_14930	COG1242	4 iron, 4 sulfur cluster binding
D0871_14935	COG0070	glutamate synthase
D0871_14935	COG0069	glutamate synthase activity
D0871_14935	COG0067	glutamate synthase
D0871_14945	COG0070	glutamate synthase
D0871_14945	COG0067	glutamate synthase
D0871_14945	COG0069	glutamate synthase activity
D0871_14950	COG0493	'glutamate synthase
D0871_14960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D0871_14970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0871_14975	COG2860	membrane
D0871_14980	COG0583	DNA-binding transcription factor activity
D0871_14985	COG0730	response to heat
D0871_15000	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
D0871_15005	COG0505	Belongs to the CarA family
D0871_15010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
D0871_15015	COG0494	nUDIX hydrolase
D0871_15020	COG0653	protein targeting
D0871_15030	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
D0871_15035	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D0871_15040	COG0849	cell division
D0871_15045	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D0871_15050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D0871_15055	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
D0871_15060	COG0772	Belongs to the SEDS family
D0871_15065	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
D0871_15070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
D0871_15075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D0871_15080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D0871_15085	COG0768	penicillin binding
D0871_15090	COG3116	cell division
D0871_15095	COG0275	rRNA processing
D0871_15110	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
D0871_15120	COG0792	nuclease activity
D0871_15125	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
D0871_15130	COG2823	Periplasmic or secreted lipoprotein
D0871_15135	COG2969	positive regulation of protein catabolic process
D0871_15140	COG0625	glutathione transferase activity
D0871_15145	COG2857	Cytochrome c1
D0871_15150	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
D0871_15155	COG0723	plastoquinol--plastocyanin reductase activity
D0871_15160	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D0871_15165	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
D0871_15175	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D0871_15185	COG3105	Protein conserved in bacteria
D0871_15195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D0871_15200	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
D0871_15205	COG0187	DNA topoisomerase II activity
D0871_15210	COG3150	esterase
D0871_15220	COG3151	Protein conserved in bacteria
D0871_15225	COG0494	nUDIX hydrolase
D0871_15230	COG1538	Outer membrane efflux protein
D0871_15235	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
D0871_15235	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
D0871_15240	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D0871_15255	COG3025	triphosphatase activity
D0871_15260	COG1392	Phosphate transport regulator
D0871_15265	COG0306	phosphate transporter
D0871_15270	COG4991	sh3 domain protein
D0871_15280	COG3267	Type II secretory pathway component ExeA
D0871_15280	COG3409	Peptidoglycan-binding domain 1 protein
D0871_15285	COG0617	tRNA 3'-terminal CCA addition
D0871_15290	COG1968	undecaprenyl-diphosphatase activity
D0871_15295	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D0871_15300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
D0871_15305	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
D0871_15310	COG0596	Alpha beta hydrolase
D0871_15315	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
D0871_15320	COG0828	Belongs to the bacterial ribosomal protein bS21 family
D0871_15325	COG1610	YqeY-like protein
D0871_15330	COG0358	DNA primase activity
D0871_15335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
D0871_15395	COG0582	viral genome integration into host DNA
D0871_15400	COG1464	Belongs to the NlpA lipoprotein family
D0871_15435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0871_15435	COG2213	PTS system mannitol-specific
D0871_15440	COG0246	Mannitol dehydrogenase
D0871_15445	COG3722	fumarate hydratase activity
D0871_15450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0871_15455	COG5002	protein histidine kinase activity
D0871_15470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D0871_15475	COG1349	DNA-binding transcription factor activity
D0871_15485	COG0469	pyruvate kinase activity
D0871_15495	COG3706	GGDEF domain
D0871_15500	COG0440	acetolactate synthase activity
D0871_15505	COG0028	Belongs to the TPP enzyme family
D0871_15510	COG1022	Amp-dependent synthetase and ligase
D0871_15515	COG0583	DNA-binding transcription factor activity
D0871_15535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D0871_15540	COG0473	3-isopropylmalate dehydrogenase activity
D0871_15545	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
D0871_15550	COG0066	3-isopropylmalate dehydratase activity
D0871_15560	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
D0871_15565	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
D0871_15570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0871_15575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
D0871_15580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D0871_15585	COG2967	ApaG domain
D0871_15590	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D0871_15605	COG2966	Psort location CytoplasmicMembrane, score
D0871_15610	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D0871_15620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
D0871_15625	COG0142	geranyltranstransferase activity
D0871_15635	COG0039	L-malate dehydrogenase activity
D0871_15670	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
D0871_15675	COG1178	ABC-type Fe3 transport system permease component
D0871_15680	COG4143	(ABC) transporter
D0871_15685	COG0163	prenyltransferase activity
D0871_15690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D0871_15700	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D0871_15705	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D0871_15715	COG2105	PFAM AIG2 family protein
D0871_15720	COG2911	Protein conserved in bacteria
D0871_15725	COG0729	surface antigen
D0871_15730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0871_15740	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
D0871_15755	COG1136	(ABC) transporter
D0871_15775	COG0529	Catalyzes the synthesis of activated sulfate
D0871_15780	COG0471	metal ion transport
D0871_15780	COG3273	potassium ion transport
D0871_15790	COG2895	sulfate adenylyltransferase (ATP) activity
D0871_15795	COG0175	sulfate reduction
D0871_15800	COG1648	precorrin-2 dehydrogenase activity
D0871_15800	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D0871_15805	COG0737	Belongs to the 5'-nucleotidase family
D0871_15815	COG0513	Belongs to the DEAD box helicase family
D0871_15820	COG2153	protein acetylation
D0871_15830	COG0545	Peptidyl-prolyl cis-trans isomerase
D0871_15840	COG0203	ribosomal protein L17
D0871_15845	COG0202	RNA polymerase activity
D0871_15855	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
D0871_15860	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D0871_15870	COG0201	protein transport
D0871_15875	COG0200	Binds to the 23S rRNA
D0871_15880	COG1841	ribosomal large subunit assembly
D0871_15895	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
D0871_15900	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
D0871_15905	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
D0871_15910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D0871_15915	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
D0871_15920	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
D0871_15925	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
D0871_15930	COG0255	Belongs to the universal ribosomal protein uL29 family
D0871_15940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
D0871_15945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
D0871_15950	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
D0871_15955	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D0871_15965	COG0088	Forms part of the polypeptide exit tunnel
D0871_15970	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
D0871_15980	COG0254	rRNA binding
D0871_15990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D0871_15995	COG1609	Transcriptional regulator
D0871_16005	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
D0871_16010	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
D0871_16025	COG2003	Belongs to the UPF0758 family
D0871_16055	COG1575	Belongs to the MenA family. Type 1 subfamily
D0871_16060	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D0871_16065	COG3074	FtsZ-dependent cytokinesis
D0871_16075	COG1494	fructose-1,6-bisphosphatase
D0871_16100	COG0149	triose-phosphate isomerase activity
D0871_16105	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
D0871_16125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D0871_16145	COG0438	transferase activity, transferring glycosyl groups
D0871_16165	COG1215	transferase activity, transferring glycosyl groups
D0871_16170	COG0110	maltose O-acetyltransferase activity
D0871_16180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
D0871_16230	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D0871_16240	COG1560	Kdo2-lipid A biosynthetic process
D0871_16245	COG0859	PFAM glycosyl transferase family 9
D0871_16250	COG1519	Transferase
D0871_16260	COG0438	transferase activity, transferring glycosyl groups
D0871_16260	COG0297	glycogen (starch) synthase activity
D0871_16280	COG2030	dehydratase
D0871_16285	COG0110	maltose O-acetyltransferase activity
D0871_16305	COG3642	lipopolysaccharide core region biosynthetic process
D0871_16310	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D0871_16315	COG0859	PFAM glycosyl transferase family 9
D0871_16320	COG0463	Glycosyl transferase, family 2
D0871_16325	COG0438	transferase activity, transferring glycosyl groups
D0871_16340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
D0871_16355	COG0227	Belongs to the bacterial ribosomal protein bL28 family
D0871_16360	COG2003	Belongs to the UPF0758 family
D0871_16375	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D0871_16380	COG1309	transcriptional regulator
D0871_16385	COG1560	Kdo2-lipid A biosynthetic process
D0871_16390	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
D0871_16395	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
D0871_16400	COG1561	YicC-like family, N-terminal region
D0871_16410	COG4608	Belongs to the ABC transporter superfamily
D0871_16415	COG0444	Belongs to the ABC transporter superfamily
D0871_16420	COG0747	negative chemotaxis
D0871_16425	COG4239	(ABC) transporter, permease
D0871_16430	COG4174	ABC transporter (Permease)
D0871_16455	COG0811	peptide transport
D0871_16460	COG0848	biopolymer transport protein
D0871_16475	COG0194	GDP metabolic process
D0871_16480	COG1758	RNA polymerase activity
D0871_16485	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D0871_16490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D0871_16495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D0871_16505	COG2233	PERMEase
D0871_16510	COG2205	protein histidine kinase activity
D0871_16515	COG0745	RESPONSE REGULATOR receiver
D0871_16525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0871_16535	COG2183	response to ionizing radiation
D0871_16545	COG0596	Alpha beta hydrolase
D0871_16550	COG1040	competence protein
D0871_16555	COG0316	Belongs to the HesB IscA family
D0871_16555	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
D0871_16560	COG0494	nUDIX hydrolase
D0871_16565	COG1218	3'(2'),5'-bisphosphate nucleotidase
D0871_16575	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
D0871_16580	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
D0871_16585	COG3156	type II secretion system protein K
D0871_16590	COG4795	General secretion pathway protein
D0871_16595	COG2165	general secretion pathway protein
D0871_16600	COG2165	general secretion pathway protein
D0871_16605	COG2165	general secretion pathway protein
D0871_16610	COG1459	type II secretion system
D0871_16615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D0871_16625	COG3031	protein transport across the cell outer membrane
D0871_16630	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D0871_16635	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D0871_16640	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
D0871_16650	COG0456	acetyltransferase
D0871_16655	COG1490	D-aminoacyl-tRNA deacylase activity
D0871_16660	COG1295	ribonuclease BN
D0871_16680	COG0174	glutamine synthetase
D0871_16690	COG3852	Histidine kinase
D0871_16695	COG2204	response regulator
D0871_16705	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D0871_16710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D0871_16745	COG0218	Necessary for normal cell division and for the maintenance of normal septation
D0871_16755	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0871_16755	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
D0871_16780	COG0084	hydrolase, TatD family'
D0871_16790	COG0805	protein transport
D0871_16800	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
D0871_16805	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D0871_16810	COG3165	ubiquinone biosynthetic process from chorismate
D0871_16815	COG2226	methyltransferase
D0871_16820	COG1322	Protein conserved in bacteria
D0871_16835	COG0628	permease
D0871_16885	COG2823	Periplasmic or secreted lipoprotein
D0871_16895	COG2081	HI0933 family
D0871_16905	COG1528	Iron-storage protein
D0871_16910	COG0589	response to stress
D0871_16915	COG0697	spore germination
D0871_16925	COG0742	ribosomal rna small subunit methyltransferase
D0871_16930	COG5002	protein histidine kinase activity
D0871_16930	COG5001	Diguanylate cyclase
D0871_16935	COG1522	sequence-specific DNA binding
D0871_16940	COG0339	signal peptide processing
D0871_16950	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D0871_16955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D0871_16980	COG3328	transposase activity
D0871_16985	COG1404	Belongs to the peptidase S8 family
D0871_16990	COG0464	growth
D0871_17010	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
D0871_17050	COG0640	Transcriptional regulator
D0871_17065	COG0786	glutamate:sodium symporter activity
D0871_17085	COG0583	DNA-binding transcription factor activity
D0871_17090	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
D0871_17095	COG0800	Aldolase
D0871_17100	COG2610	gluconate transmembrane transporter activity
D0871_17105	COG3265	gluconokinase activity
D0871_17110	COG0129	dihydroxy-acid dehydratase activity
D0871_17115	COG2076	Multidrug Resistance protein
D0871_17125	COG0583	DNA-binding transcription factor activity
D0871_17130	COG1609	Transcriptional regulator
D0871_17170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D0871_17180	COG0747	negative chemotaxis
D0871_17250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0871_17255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0871_17265	COG2960	long-chain fatty acid transporting porin activity
D0871_17270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
D0871_17275	COG0583	DNA-binding transcription factor activity
D0871_17320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D0871_17330	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
D0871_17335	COG0408	coproporphyrinogen oxidase activity
D0871_17340	COG0009	L-threonylcarbamoyladenylate synthase
D0871_17345	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
D0871_17350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D0871_17355	COG0551	DNA topoisomerase type I activity
D0871_17360	COG2922	Belongs to the Smg family
D0871_17365	COG0758	DNA mediated transformation
D0871_17375	COG0242	peptide deformylase activity
D0871_17380	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
D0871_17385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
D0871_17385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
D0871_17390	COG0569	domain protein
D0871_17395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0871_17405	COG1272	protein, Hemolysin III
D0871_17410	COG4326	sporulation control protein
D0871_17420	COG3084	Protein conserved in bacteria
D0871_17430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D0871_17435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0871_17440	COG0204	Acyl-transferase
D0871_17500	COG0606	chelatase, subunit chli
D0871_17510	COG3978	acetolactate synthase activity
D0871_17515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D0871_17520	COG0129	dihydroxy-acid dehydratase activity
D0871_17530	COG0583	DNA-binding transcription factor activity
D0871_17535	COG2814	Major facilitator Superfamily
D0871_17540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0871_17545	COG0765	amino acid transport
D0871_17550	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
D0871_17555	COG0355	proton-transporting ATP synthase activity, rotational mechanism
D0871_17560	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
D0871_17565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
D0871_17570	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
D0871_17575	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
D0871_17590	COG0356	it plays a direct role in the translocation of protons across the membrane
D0871_17595	COG3312	ion transport
D0871_17600	COG1475	DNA binding
D0871_17605	COG1192	Involved in chromosome partitioning
D0871_17610	COG0357	Ribosomal RNA small subunit methyltransferase G
D0871_17615	COG0445	tRNA wobble uridine modification
D0871_17620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D0871_17625	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
D0871_17630	COG0706	membrane insertase activity
D0871_17635	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
D0871_17640	COG0594	ribonuclease P activity
D0871_17650	COG1126	abc transporter atp-binding protein
D0871_17690	COG1181	Belongs to the D-alanine--D-alanine ligase family
D0871_17700	COG0023	Translation Initiation Factor
D0871_17750	COG4128	Pfam Zonular occludens toxin
D0871_17785	COG0583	DNA-binding transcription factor activity
D0871_17795	COG0589	response to stress
D0871_17800	COG3140	Belongs to the UPF0181 family
D0871_17825	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
D0871_17830	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
D0871_17845	COG3706	GGDEF domain
D0871_17845	COG0745	RESPONSE REGULATOR receiver
D0871_17855	COG2203	Gaf domain
D0871_17855	COG3706	GGDEF domain
D0871_17855	COG5001	Diguanylate cyclase
D0871_17855	COG4251	negative regulation of phosphorylation
D0871_17865	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D0871_17870	COG4149	molybdate abc transporter
D0871_17875	COG0725	ABC transporter, periplasmic molybdate-binding protein
D0871_17880	COG1492	cobalamin metabolic process
D0871_17885	COG3111	PFAM Bacterial OB fold (BOF) protein
D0871_17895	COG0189	ligase activity
D0871_17895	COG4067	protein conserved in archaea
D0871_17915	COG0534	Mate efflux family protein
D0871_17920	COG0602	queuosine metabolic process
D0871_17925	COG1328	CTP reductase activity
D0871_17940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0871_17970	COG0243	molybdopterin cofactor binding
D0871_17980	COG0583	DNA-binding transcription factor activity
D0871_17985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D0871_17995	COG2197	response regulator
D0871_18000	COG3851	Histidine kinase
D0871_18005	COG2271	Major facilitator Superfamily
D0871_18030	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
D0871_18035	COG3118	belongs to the thioredoxin family
D0871_18040	COG2814	Major facilitator Superfamily
D0871_18050	COG0534	Mate efflux family protein
D0871_18085	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
D0871_18105	COG2116	formate transmembrane transporter activity
D0871_18110	COG2146	nitrite reductase [NAD(P)H] activity
D0871_18115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0871_18120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D0871_18205	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D0871_18225	COG0277	FAD linked oxidase domain protein
D0871_18230	COG0583	DNA-binding transcription factor activity
D0871_18250	COG2425	protein containing a von Willebrand factor type A (vWA) domain
D0871_18265	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D0871_18280	COG1288	antiporter activity
D0871_18290	COG2814	Major facilitator Superfamily
D0871_18300	COG3040	lipid binding
D0871_18320	COG0419	ATPase involved in DNA repair
D0871_18325	COG0420	3'-5' exonuclease activity
D0871_18340	COG3501	Rhs element vgr protein
D0871_18395	COG0631	protein serine/threonine phosphatase activity
D0871_18430	COG2815	serine threonine protein kinase
D0871_18430	COG0515	serine threonine protein kinase
D0871_18485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D0871_18485	COG2146	nitrite reductase [NAD(P)H] activity
D0871_18490	COG1116	anion transmembrane transporter activity
D0871_18500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D0871_18510	COG3707	response regulator
D0871_18530	COG1648	precorrin-2 dehydrogenase activity
D0871_18530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D0871_18535	COG0243	molybdopterin cofactor binding
D0871_18540	COG0456	acetyltransferase
D0871_18545	COG0814	amino acid
D0871_18555	COG0745	RESPONSE REGULATOR receiver
D0871_18555	COG3706	GGDEF domain
D0871_18575	COG1785	Belongs to the alkaline phosphatase family
D0871_18590	COG0745	RESPONSE REGULATOR receiver
D0871_18610	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
D0871_18625	COG1609	Transcriptional regulator
D0871_18630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0871_18635	COG1879	ABC-type sugar transport system periplasmic component
D0871_18640	COG1172	Belongs to the binding-protein-dependent transport system permease family
D0871_18645	COG1129	ABC transporter
D0871_18650	COG1869	D-ribose catabolic process
D0871_18655	COG5001	Diguanylate cyclase
D0871_18660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D0871_18720	COG0784	Response regulator, receiver
D0871_18720	COG2205	protein histidine kinase activity
D0871_18740	COG5001	Diguanylate cyclase
D0871_18740	COG3300	MHYT domain
D0871_18750	COG0330	HflC and HflK could
D0871_18765	COG4175	Glycine betaine
D0871_18765	COG0517	IMP dehydrogenase activity
D0871_18770	COG4176	ABC-type proline glycine betaine transport system permease component
D0871_18785	COG1012	belongs to the aldehyde dehydrogenase family
D0871_18790	COG1309	transcriptional regulator
D0871_18795	COG3706	GGDEF domain
D0871_18820	COG1024	Enoyl-CoA hydratase
D0871_18825	COG1960	acyl-CoA dehydrogenase activity
D0871_18835	COG0183	Belongs to the thiolase family
D0871_18845	COG1960	acyl-CoA dehydrogenase activity
D0871_18850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D0871_18855	COG1024	Enoyl-CoA hydratase
D0871_18870	COG4999	Histidine kinase
D0871_18870	COG3850	Histidine kinase
D0871_18870	COG3437	response regulator, receiver
D0871_18870	COG2205	protein histidine kinase activity
D0871_18885	COG3264	Mechanosensitive ion channel
D0871_18885	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
D0871_18895	COG0110	maltose O-acetyltransferase activity
D0871_18900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0871_18905	COG1271	oxidase subunit
D0871_18910	COG1294	oxidase, subunit
D0871_18920	COG0384	phenazine biosynthesis protein PhzF
D0871_18925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D0871_18930	COG0789	Transcriptional regulator
D0871_18940	COG3474	cytochrome
D0871_19010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0871_19015	COG0516	GMP reductase activity
D0871_19020	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D0871_19020	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D0871_19035	COG4989	oxidoreductase activity
D0871_19050	COG0038	chloride channel
D0871_19060	COG1914	H( )-stimulated, divalent metal cation uptake system
D0871_19065	COG0302	gtp cyclohydrolase
D0871_19075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
D0871_19095	COG2897	thiosulfate sulfurtransferase activity
D0871_19125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D0871_19130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D0871_19135	COG0840	transmembrane signaling receptor activity
D0871_19145	COG2814	Major facilitator Superfamily
D0871_19150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D0871_19165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0871_19175	COG0840	transmembrane signaling receptor activity
D0871_19195	COG2195	Cleaves the N-terminal amino acid of tripeptides
D0871_19210	COG2197	response regulator
D0871_19215	COG3850	Histidine kinase
D0871_19220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D0871_19230	COG0243	molybdopterin cofactor binding
D0871_19240	COG3005	denitrification pathway
D0871_19260	COG0183	Belongs to the thiolase family
D0871_19280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0871_19285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D0871_19315	COG1522	sequence-specific DNA binding
D0871_19335	COG1566	PFAM secretion protein HlyD family protein
D0871_19345	COG0784	Response regulator, receiver
D0871_19345	COG2205	protein histidine kinase activity
D0871_19350	COG1879	ABC-type sugar transport system periplasmic component
D0871_19355	COG2827	Endonuclease containing a URI domain
D0871_19360	COG3132	Protein of unknown function, DUF480
D0871_19375	COG2926	Belongs to the UPF0265 family
D0871_19380	COG0534	Mate efflux family protein
D0871_19385	COG0673	inositol 2-dehydrogenase activity
D0871_19390	COG5002	protein histidine kinase activity
D0871_19390	COG2205	protein histidine kinase activity
D0871_19390	COG0784	Response regulator, receiver
D0871_19410	COG0583	DNA-binding transcription factor activity
D0871_19415	COG1522	sequence-specific DNA binding
D0871_19425	COG0531	amino acid
D0871_19440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D0871_19445	COG2239	Acts as a magnesium transporter
D0871_19450	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D0871_19455	COG0402	S-adenosylhomocysteine deaminase activity
D0871_19465	COG1418	mRNA catabolic process
D0871_19480	COG2814	Major facilitator Superfamily
D0871_19490	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0871_19510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D0871_19530	COG4221	oxidoreductase activity
D0871_19535	COG0745	RESPONSE REGULATOR receiver
D0871_19540	COG2205	protein histidine kinase activity
D0871_19550	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
D0871_19555	COG2194	sulfuric ester hydrolase activity
D0871_19560	COG0673	inositol 2-dehydrogenase activity
D0871_19570	COG2814	Major facilitator Superfamily
D0871_19585	COG1846	Transcriptional regulator
D0871_19595	COG4667	esterase of the alpha-beta hydrolase superfamily
D0871_19600	COG1741	Belongs to the pirin family
D0871_19605	COG1278	Cold shock
D0871_19625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D0871_19645	COG1686	Belongs to the peptidase S11 family
D0871_19660	COG0625	glutathione transferase activity
D0871_19670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D0871_19690	COG1028	Short-chain dehydrogenase reductase Sdr
D0871_19705	COG3746	phosphate-selective porin O and P
D0871_19725	COG3833	ABC-type maltose transport systems, permease component
D0871_19730	COG1175	transmembrane transport
D0871_19740	COG3842	ATPase activity
D0871_19805	COG1309	transcriptional regulator
D0871_19810	COG2130	NADP-dependent
D0871_19820	COG0753	catalase activity
D0871_19825	COG2084	Dehydrogenase
D0871_19830	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0871_19835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0871_19845	COG2207	Transcriptional regulator
D0871_19850	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0871_19850	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0871_19850	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0871_19865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0871_19870	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
D0871_19880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D0871_19885	COG0569	domain protein
D0871_19895	COG5002	protein histidine kinase activity
D0871_19900	COG1132	(ABC) transporter
D0871_19905	COG4774	siderophore transport
D0871_19910	COG1120	ATPase activity
D0871_19915	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D0871_19965	COG2197	response regulator
D0871_19975	COG0840	transmembrane signaling receptor activity
D0871_19985	COG0714	Associated with various cellular activities
D0871_20005	COG2304	oxidoreductase activity
D0871_20020	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D0871_20025	COG0581	inorganic phosphate transmembrane transporter activity
D0871_20030	COG0573	inorganic phosphate transmembrane transporter activity
D0871_20035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D0871_20060	COG4771	TonB-dependent receptor
D0871_20065	COG1770	oligopeptidase
D0871_20070	COG0513	Belongs to the DEAD box helicase family
D0871_20080	COG1388	LysM domain
D0871_20080	COG1376	ErfK ybiS ycfS ynhG family protein
D0871_20085	COG0415	Belongs to the DNA photolyase family
D0871_20090	COG0789	Transcriptional regulator
D0871_20095	COG3272	Protein of unknown function (DUF1722)
D0871_20105	COG0813	purine-nucleoside phosphorylase activity
D0871_20120	COG3706	GGDEF domain
D0871_20130	COG1566	PFAM secretion protein HlyD family protein
D0871_20135	COG4720	Psort location CytoplasmicMembrane, score
D0871_20140	COG1122	ATPase activity
D0871_20155	COG0348	domain, Protein
D0871_20160	COG0437	4 iron, 4 sulfur cluster binding
D0871_20165	COG1247	-acetyltransferase
D0871_20195	COG1067	ATP-dependent peptidase activity
D0871_20205	COG4172	Belongs to the ABC transporter superfamily
D0871_20210	COG1505	serine-type exopeptidase activity
D0871_20215	COG0583	DNA-binding transcription factor activity
D0871_20220	COG1620	l-lactate permease
D0871_20225	COG1304	FMN binding
D0871_20235	COG0668	transmembrane transport
D0871_20270	COG1063	alcohol dehydrogenase
D0871_20275	COG0156	8-amino-7-oxononanoate synthase activity
D0871_20285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0871_20305	COG0745	RESPONSE REGULATOR receiver
D0871_20340	COG0346	lactoylglutathione lyase activity
D0871_20360	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D0871_20400	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
D0871_20415	COG2204	response regulator
D0871_20440	COG1987	bacterial-type flagellum assembly
D0871_20450	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
D0871_20465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0871_20475	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
D0871_20480	COG1516	flagellar protein fliS
D0871_20495	COG1580	Controls the rotational direction of flagella during chemotaxis
D0871_20500	COG1191	sigma factor activity
D0871_20505	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
D0871_20510	COG1360	Flagellar Motor Protein
D0871_20565	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
D0871_20570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D0871_20580	COG0454	-acetyltransferase
D0871_20595	COG2814	Major facilitator Superfamily
D0871_20640	COG0628	permease
D0871_20645	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
D0871_20655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D0871_20665	COG4628	conserved protein (DUF2132)
D0871_20670	COG0583	DNA-binding transcription factor activity
D0871_20695	COG1686	Belongs to the peptidase S11 family
D0871_20715	COG3397	chitin binding
D0871_20720	COG4667	esterase of the alpha-beta hydrolase superfamily
D0871_20725	COG2095	MarC family integral membrane protein
D0871_20745	COG3206	protein involved in exopolysaccharide biosynthesis
D0871_20745	COG0489	protein tyrosine kinase activity
D0871_20760	COG0583	DNA-binding transcription factor activity
D0871_20770	COG1301	dicarboxylic acid transport
D0871_20775	COG3339	Conserved Protein
D0871_20780	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
D0871_20785	COG0700	Nucleoside recognition
D0871_20790	COG3366	ferrous iron transmembrane transporter activity
D0871_20805	COG0366	Alpha amylase catalytic
D0871_20810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D0871_20815	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
D0871_20820	COG1640	4-alpha-glucanotransferase
D0871_20825	COG0058	SHG alpha-glucan phosphorylase activity
D0871_20840	COG2909	trisaccharide binding
D0871_20855	COG1999	signal sequence binding
D0871_20870	COG1162	GTPase activity
D0871_20875	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
D0871_20885	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
D0871_20895	COG0531	amino acid
D0871_20900	COG1982	Orn Lys Arg decarboxylase major
D0871_20920	COG2356	endonuclease I
D0871_20930	COG0366	Alpha amylase catalytic
D0871_20945	COG4580	involved in the transport of maltose and maltodextrins
D0871_20970	COG0739	heme binding
D0871_20980	COG0612	Peptidase, M16
D0871_20985	COG0840	transmembrane signaling receptor activity
D0871_20990	COG1120	ATPase activity
D0871_20995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0871_21000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0871_21005	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
D0871_21010	COG4772	TonB-dependent receptor
D0871_21035	COG4264	IucA IucC family
D0871_21040	COG0019	diaminopimelate decarboxylase activity
D0871_21045	COG1653	transport
D0871_21055	COG0745	RESPONSE REGULATOR receiver
D0871_21095	COG0463	Glycosyl transferase, family 2
D0871_21115	COG1764	response to oxidative stress
D0871_21120	COG1846	Transcriptional regulator
D0871_21125	COG0450	alkyl hydroperoxide reductase
D0871_21130	COG3634	alkyl hydroperoxide reductase activity
D0871_21165	COG1595	DNA-templated transcription, initiation
D0871_21185	COG0583	DNA-binding transcription factor activity
D0871_21190	COG1486	melibiose metabolic process
D0871_21205	COG2258	MOSC domain
D0871_21210	COG0513	Belongs to the DEAD box helicase family
D0871_21230	COG2207	Transcriptional regulator
D0871_21240	COG1132	(ABC) transporter
D0871_21285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0871_21315	COG0259	pyridoxamine-phosphate oxidase activity
D0871_21360	COG4166	transmembrane transport
D0871_21380	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D0871_21385	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
D0871_21385	COG1263	PTS System
D0871_21390	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
D0871_21395	COG3340	Belongs to the peptidase S51 family
D0871_21415	COG1444	tRNA N-acetyltransferase activity
D0871_21445	COG4608	Belongs to the ABC transporter superfamily
D0871_21450	COG0444	Belongs to the ABC transporter superfamily
D0871_21460	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D0871_21460	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
D0871_21485	COG0217	transcriptional regulatory protein
D0871_21490	COG0772	Belongs to the SEDS family
D0871_21525	COG3275	phosphorelay sensor kinase activity
D0871_21530	COG3279	Response regulator of the LytR AlgR family
D0871_21540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D0871_21575	COG0786	glutamate:sodium symporter activity
D0871_21585	COG1131	(ABC) transporter
D0871_21590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0871_21595	COG0786	glutamate:sodium symporter activity
D0871_21610	COG0363	glucosamine-6-phosphate deaminase activity
D0871_21630	COG1741	Belongs to the pirin family
D0871_21635	COG2259	Doxx family
D0871_21650	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
D0871_21655	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D0871_21665	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
D0871_21705	COG3123	guanosine phosphorylase activity
D0871_21715	COG5001	Diguanylate cyclase
D0871_21725	COG0534	Mate efflux family protein
D0871_21730	COG0564	pseudouridine synthase activity
D0871_21745	COG0583	DNA-binding transcription factor activity
D0871_21750	COG0561	phosphatase activity
D0871_21760	COG2199	diguanylate cyclase activity
D0871_21775	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
D0871_21780	COG2162	N-hydroxyarylamine O-acetyltransferase activity
D0871_21785	COG0583	DNA-binding transcription factor activity
D0871_21800	COG1414	Transcriptional regulator
D0871_21805	COG1028	Short-chain dehydrogenase reductase Sdr
D0871_21815	COG1917	Cupin 2, conserved barrel domain protein
D0871_21830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0871_21835	COG0800	Aldolase
D0871_21855	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D0871_21860	COG0823	Involved in the tonB-independent uptake of proteins
D0871_21895	COG1357	PFAM Pentapeptide repeats (8 copies)
D0871_21900	COG3047	cAMP biosynthetic process
D0871_21930	COG3408	Glycogen debranching enzyme
D0871_21930	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
D0871_21935	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
D0871_21945	COG0583	DNA-binding transcription factor activity
D0871_21955	COG0583	DNA-binding transcription factor activity
D0871_21970	COG0546	phosphoglycolate phosphatase activity
D0871_21995	COG3835	regulator
D0871_22000	COG2610	gluconate transmembrane transporter activity
D0871_22005	COG1929	Belongs to the glycerate kinase type-1 family
D0871_22010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0871_22030	COG0456	acetyltransferase
D0871_22045	COG1028	Short-chain dehydrogenase reductase Sdr
D0871_22055	COG3005	denitrification pathway
D0871_22060	COG0243	molybdopterin cofactor binding
D0871_22070	COG0352	thiamine-phosphate diphosphorylase activity
D0871_22075	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
D0871_22080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D0871_22085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D0871_22090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D0871_22095	COG1116	anion transmembrane transporter activity
D0871_22100	COG0351	phosphomethylpyrimidine kinase
D0871_22110	COG0312	modulator of DNA gyrase
D0871_22115	COG0312	modulator of DNA gyrase
D0871_22120	COG1901	pseudouridine methyltransferase
D0871_22180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
D0871_22190	COG0584	glycerophosphoryl diester phosphodiesterase
D0871_22200	COG0745	RESPONSE REGULATOR receiver
D0871_22220	COG0811	peptide transport
D0871_22225	COG0811	peptide transport
D0871_22230	COG0848	biopolymer transport protein
D0871_22270	COG0803	Belongs to the bacterial solute-binding protein 9 family
D0871_22275	COG1121	(ABC) transporter
D0871_22280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D0871_22295	COG1770	oligopeptidase
D0871_22300	COG2814	Major facilitator Superfamily
D0871_22305	COG0010	Belongs to the arginase family
D0871_22310	COG1166	arginine decarboxylase activity
D0871_22320	COG4067	protein conserved in archaea
D0871_22320	COG0189	ligase activity
D0871_22325	COG0189	ligase activity
D0871_22335	COG0583	DNA-binding transcription factor activity
D0871_22370	COG4191	Histidine kinase
D0871_22380	COG3706	GGDEF domain
D0871_22410	COG0579	oxidoreductase
D0871_22420	COG3033	Beta-eliminating lyase
D0871_22440	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
D0871_22450	COG3145	DNA-N1-methyladenine dioxygenase activity
D0871_22455	COG3706	GGDEF domain
D0871_22460	COG0840	transmembrane signaling receptor activity
D0871_22475	COG3706	GGDEF domain
D0871_22485	COG3046	protein related to deoxyribodipyrimidine photolyase
D0871_22500	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0871_22500	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
D0871_22505	COG1765	OsmC-like protein
D0871_22510	COG0110	maltose O-acetyltransferase activity
D0871_22550	COG1011	Hydrolase
D0871_22565	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
D0871_22575	COG2067	long-chain fatty acid transport protein
D0871_22580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0871_22585	COG1136	(ABC) transporter
D0871_22585	COG0577	efflux transmembrane transporter activity
D0871_22595	COG3240	lipase activity
D0871_22625	COG1609	Transcriptional regulator
D0871_22630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D0871_22640	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D0871_22645	COG1840	ABC-type Fe3 transport system, periplasmic component
D0871_22655	COG3842	ATPase activity
D0871_22680	COG2990	Protein conserved in bacteria
D0871_22690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D0871_22695	COG2866	Carboxypeptidase
D0871_22710	COG0583	DNA-binding transcription factor activity
D0871_22735	COG1760	l-serine dehydratase
D0871_22755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D0871_22765	COG0741	lytic transglycosylase activity
D0871_22785	COG1815	bacterial-type flagellum-dependent cell motility
D0871_22790	COG1558	bacterial-type flagellum-dependent cell motility
D0871_22795	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
D0871_22800	COG1749	Flagellar hook protein flgE
D0871_22805	COG4787	bacterial-type flagellum-dependent cell motility
D0871_22810	COG4786	Flagellar basal body rod
D0871_22815	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
D0871_22820	COG1706	bacterial-type flagellum-dependent cell motility
D0871_22830	COG1256	bacterial-type flagellum assembly
D0871_22830	COG4786	Flagellar basal body rod
D0871_22835	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
D0871_22855	COG1304	FMN binding
D0871_22880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
D0871_22890	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
D0871_22895	COG0459	protein refolding
D0871_22910	COG1280	lysine exporter protein (LysE YggA)
D0871_22930	COG1309	transcriptional regulator
D0871_22940	COG0737	Belongs to the 5'-nucleotidase family
D0871_22945	COG2070	2-Nitropropane dioxygenase
D0871_22950	COG3537	Alpha-1,2-mannosidase
D0871_22955	COG3537	Alpha-1,2-mannosidase
D0871_22965	COG3537	Alpha-1,2-mannosidase
D0871_22970	COG3537	Alpha-1,2-mannosidase
D0871_22975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0871_22990	COG0346	lactoylglutathione lyase activity
D0871_22995	COG1349	DNA-binding transcription factor activity
D0871_23005	COG0753	catalase activity
D0871_23015	COG1335	isochorismatase
D0871_23025	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
D0871_23050	COG0583	DNA-binding transcription factor activity
D0871_23065	COG3713	MltA-interacting MipA family protein
D0871_23075	COG3015	lipoprotein NlpE involved in copper resistance
D0871_23085	COG1342	Belongs to the UPF0251 family
D0871_23110	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
D0871_23120	COG4948	Mandelate Racemase Muconate Lactonizing
D0871_23130	COG0583	DNA-binding transcription factor activity
D0871_23180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D0871_23225	COG3842	ATPase activity
D0871_23255	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D0871_23275	COG3706	GGDEF domain
D0871_23310	COG2842	Transposition protein
D0871_23365	COG3012	SEC-C Motif Domain Protein
D0871_23560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0871_23575	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
D0871_23580	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D0871_23600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D0871_23600	COG0574	Belongs to the PEP-utilizing enzyme family
D0871_23605	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
D0871_23610	COG0252	asparaginase activity
D0871_23620	COG0583	DNA-binding transcription factor activity
D0871_23635	COG3122	Protein conserved in bacteria
D0871_23650	COG1028	Short-chain dehydrogenase reductase Sdr
D0871_23660	COG1063	alcohol dehydrogenase
D0871_23665	COG1902	pentaerythritol trinitrate reductase activity
D0871_23680	COG0583	DNA-binding transcription factor activity
D0871_23690	COG0513	Belongs to the DEAD box helicase family
D0871_23735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D0871_23740	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
D0871_23740	COG2207	Transcriptional regulator
D0871_23770	COG2354	Protein conserved in bacteria
D0871_23775	COG0418	dihydroorotase activity
D0871_23785	COG0401	homolog of Blt101
D0871_23795	COG3217	Mosc domain protein beta barrel domain protein
D0871_23795	COG0633	Ferredoxin
D0871_23795	COG0633	Ferredoxin
D0871_23795	COG3217	Mosc domain protein beta barrel domain protein
D0871_23800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D0871_23805	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
D0871_23850	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
D0871_23855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0871_23865	COG0848	biopolymer transport protein
D0871_23870	COG0811	peptide transport
D0871_23875	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
D0871_23885	COG3721	Heme iron utilization protein
D0871_23890	COG0748	coenzyme F420 binding
D0871_23900	COG0784	Response regulator, receiver
D0871_23900	COG0835	chemotaxis
D0871_23905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D0871_23920	COG2211	Major facilitator Superfamily
D0871_23925	COG1069	ribulokinase activity
D0871_23935	COG2160	L-arabinose isomerase activity
D0871_23940	COG0561	phosphatase activity
D0871_23950	COG2017	converts alpha-aldose to the beta-anomer
D0871_23955	COG3940	Belongs to the glycosyl hydrolase 43 family
D0871_23960	COG2211	Major facilitator Superfamily
D0871_23985	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
D0871_23990	COG0783	Belongs to the Dps family
D0871_24000	COG0583	DNA-binding transcription factor activity
D0871_24015	COG4934	collagen metabolic process
D0871_24025	COG0366	Alpha amylase catalytic
D0871_24045	COG2249	NAD(P)H dehydrogenase (quinone) activity
D0871_24050	COG0589	response to stress
D0871_24055	COG0488	(ABC) transporter
D0871_24060	COG1505	serine-type exopeptidase activity
D0871_24070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0871_24080	COG2067	long-chain fatty acid transport protein
D0871_24090	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
D0871_24100	COG2199	diguanylate cyclase activity
D0871_24100	COG2203	Gaf domain
D0871_24120	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D0871_24145	COG3383	formate dehydrogenase (NAD+) activity
D0871_24160	COG0842	Transport permease protein
D0871_24165	COG1131	(ABC) transporter
D0871_24185	COG2706	6-phosphogluconolactonase activity
D0871_24195	COG1881	PFAM PEBP family protein
D0871_24205	COG0798	PFAM Bile acid sodium symporter
D0871_24225	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0871_24230	COG2213	PTS system mannitol-specific
D0871_24235	COG1063	alcohol dehydrogenase
D0871_24245	COG1072	(Pantothenic acid kinase))
D0871_24250	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
D0871_24270	COG0814	amino acid
D0871_24310	COG0739	heme binding
D0871_24315	COG5001	Diguanylate cyclase
D0871_24320	COG0583	DNA-binding transcription factor activity
D0871_24325	COG2814	Major facilitator Superfamily
D0871_24350	COG0697	spore germination
D0871_24380	COG2207	Transcriptional regulator
D0871_24385	COG1280	lysine exporter protein (LysE YggA)
D0871_24395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D0871_24400	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D0871_24410	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
D0871_24435	COG1612	heme a metabolic process
D0871_24440	COG0109	protoheme IX farnesyltransferase activity
D0871_24445	COG0545	Peptidyl-prolyl cis-trans isomerase
D0871_24480	COG1278	Cold shock
D0871_24485	COG3036	rescue of stalled ribosome
D0871_24500	COG2199	diguanylate cyclase activity
D0871_24520	COG0577	efflux transmembrane transporter activity
D0871_24520	COG1136	(ABC) transporter
D0871_24530	COG0840	transmembrane signaling receptor activity
D0871_24540	COG0783	Belongs to the Dps family
D0871_24550	COG2133	pyrroloquinoline quinone binding
D0871_24555	COG1454	alcohol dehydrogenase
D0871_24560	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
D0871_24600	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D0871_24605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D0871_24610	COG3186	Phenylalanine-4-hydroxylase
D0871_24615	COG2154	pterin-4-alpha-carbinolamine dehydratase
D0871_24640	COG3530	Putative quorum-sensing-regulated virulence factor
D0871_24645	COG0513	Belongs to the DEAD box helicase family
D0871_24650	COG4628	conserved protein (DUF2132)
D0871_24655	COG0133	tryptophan synthase activity
D0871_24665	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
D0871_24675	COG0523	cobalamin synthesis protein
D0871_24680	COG0513	Belongs to the DEAD box helicase family
D0871_24700	COG2200	EAL domain
D0871_24705	COG1119	ATPase activity
D0871_24710	COG0840	transmembrane signaling receptor activity
D0871_24750	COG0641	radical SAM
D0871_24770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D0871_24785	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
D0871_24790	COG0513	Belongs to the DEAD box helicase family
D0871_24795	COG5001	Diguanylate cyclase
D0871_24805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D0871_24820	COG5413	integral membrane protein
D0871_24835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D0871_24840	COG1960	acyl-CoA dehydrogenase activity
D0871_24850	COG0183	Belongs to the thiolase family
D0871_24860	COG1960	acyl-CoA dehydrogenase activity
D0871_24865	COG1024	Enoyl-CoA hydratase
D0871_24870	COG1024	Enoyl-CoA hydratase
D0871_24880	COG1028	Short-chain dehydrogenase reductase Sdr
D0871_24885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D0871_24890	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D0871_24895	COG1845	cytochrome c oxidase, subunit III
D0871_24900	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D0871_24905	COG0109	protoheme IX farnesyltransferase activity
D0871_24920	COG1902	pentaerythritol trinitrate reductase activity
D0871_24950	COG1126	abc transporter atp-binding protein
D0871_24955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0871_24960	COG4215	(ABC) transporter
D0871_24965	COG4160	amino acid transport
D0871_24980	COG0625	glutathione transferase activity
D0871_25015	COG0443	Heat shock 70 kDa protein
D0871_25020	COG2847	Copper chaperone PCu(A)C
D0871_25045	COG4607	ABC-type enterochelin transport system periplasmic component
D0871_25050	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D0871_25055	COG4605	iron ion homeostasis
D0871_25060	COG4604	ABC transporter, ATP-binding protein
D0871_25065	COG0789	Transcriptional regulator
D0871_25080	COG4771	TonB-dependent receptor
D0871_25080	COG1629	transport
D0871_25115	COG1289	transmembrane transporter activity
D0871_25120	COG0210	DNA helicase
D0871_25125	COG1803	Methylglyoxal synthase
D0871_25130	COG1879	ABC-type sugar transport system periplasmic component
D0871_25135	COG2205	protein histidine kinase activity
D0871_25135	COG0784	Response regulator, receiver
D0871_25135	COG2198	Histidine kinase
D0871_25150	COG0745	RESPONSE REGULATOR receiver
D0871_25160	COG3119	arylsulfatase activity
D0871_25165	COG3119	arylsulfatase activity
D0871_25180	COG3119	arylsulfatase activity
D0871_25185	COG0641	radical SAM
D0871_25190	COG0714	Associated with various cellular activities
D0871_25220	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D0871_25225	COG0583	DNA-binding transcription factor activity
D0871_25230	COG1597	lipid kinase activity
D0871_25235	COG3111	PFAM Bacterial OB fold (BOF) protein
D0871_25255	COG0641	radical SAM
D0871_25285	COG0501	Belongs to the peptidase M48B family
D0871_25290	COG1704	LemA family
D0871_25295	COG3069	C4-dicarboxylate transmembrane transporter activity
D0871_25305	COG0456	acetyltransferase
D0871_25305	COG1214	PFAM Peptidase M22, glycoprotease
D0871_25325	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
D0871_25345	COG2207	Transcriptional regulator
D0871_25370	COG4964	Belongs to the GSP D family
D0871_25430	COG0583	DNA-binding transcription factor activity
D0871_25435	COG0583	DNA-binding transcription factor activity
D0871_25450	COG5001	Diguanylate cyclase
D0871_25450	COG3300	MHYT domain
D0871_25455	COG2197	response regulator
D0871_25460	COG3706	GGDEF domain
D0871_25470	COG2197	response regulator
D0871_25495	COG0835	chemotaxis
D0871_25495	COG0784	Response regulator, receiver
D0871_25515	COG2962	Rard protein
D0871_25530	COG0671	phosphoesterase, PA-phosphatase related
D0871_25545	COG2076	Multidrug Resistance protein
D0871_25575	COG0471	metal ion transport
D0871_25580	COG3290	protein histidine kinase activity
D0871_25585	COG4565	transcriptional regulatory protein
D0871_25595	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D0871_25595	COG0069	glutamate synthase activity
D0871_25605	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
D0871_25630	COG1902	pentaerythritol trinitrate reductase activity
D0871_25635	COG0346	lactoylglutathione lyase activity
D0871_25655	COG2239	Acts as a magnesium transporter
D0871_25675	COG0242	peptide deformylase activity
D0871_25720	COG2176	DNA-directed DNA polymerase activity
D0871_25725	COG0583	DNA-binding transcription factor activity
D0871_25730	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
D0871_25735	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
D0871_25755	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D0871_25755	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D0871_25760	COG0509	glycine decarboxylation via glycine cleavage system
D0871_25765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
D0871_25785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D0871_25805	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0871_25805	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
D0871_25805	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D0871_25810	COG1105	Belongs to the carbohydrate kinase PfkB family
D0871_25815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0871_25815	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D0871_25820	COG1609	Transcriptional regulator
D0871_25840	COG2200	EAL domain
D0871_25840	COG2199	diguanylate cyclase activity
D0871_25840	COG2203	Gaf domain
D0871_25845	COG0765	amino acid transport
D0871_25850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D0871_25855	COG0765	amino acid transport
D0871_25860	COG1126	abc transporter atp-binding protein
D0871_25865	COG0469	pyruvate kinase activity
D0871_25870	COG2271	Major facilitator Superfamily
D0871_25875	COG1840	ABC-type Fe3 transport system, periplasmic component
D0871_25895	COG1979	alcohol dehydrogenase
D0871_25900	COG2207	Transcriptional regulator
D0871_25915	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
D0871_25920	COG2759	Belongs to the formate--tetrahydrofolate ligase family
D0871_25925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D0871_25945	COG0784	Response regulator, receiver
D0871_25945	COG3437	response regulator, receiver
D0871_25955	COG0546	phosphoglycolate phosphatase activity
D0871_25975	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
D0871_25980	COG0513	Belongs to the DEAD box helicase family
D0871_25985	COG4943	cyclic-guanylate-specific phosphodiesterase activity
D0871_26000	COG3038	cytochrome b561
D0871_26005	COG2353	YceI-like domain
D0871_26010	COG2116	formate transmembrane transporter activity
D0871_26020	COG0583	DNA-binding transcription factor activity
D0871_26030	COG3593	DNA synthesis involved in DNA repair
D0871_26035	COG0737	Belongs to the 5'-nucleotidase family
D0871_26040	COG0861	Integral membrane protein TerC family
D0871_26055	COG2267	carboxylic ester hydrolase activity
D0871_26060	COG2067	long-chain fatty acid transport protein
D0871_26075	COG2050	protein possibly involved in aromatic compounds catabolism
D0871_26085	COG4533	DNA binding
D0871_26110	COG0484	heat shock protein binding
D0871_26120	COG3300	MHYT domain
D0871_26120	COG5001	Diguanylate cyclase
D0871_26125	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D0871_26135	COG4181	ATPase activity
D0871_26140	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
D0871_26150	COG1984	allophanate hydrolase subunit 2
D0871_26155	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
D0871_26160	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
D0871_26165	COG5001	Diguanylate cyclase
D0871_26165	COG3447	MASE1 domain protein
D0871_26165	COG5002	protein histidine kinase activity
D0871_26170	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D0871_26190	COG5492	domain, Protein
D0871_26190	COG4932	domain protein
D0871_26225	COG2885	chlorophyll binding
D0871_26280	COG2337	Toxic component of a toxin-antitoxin (TA) module
D0871_26290	COG4974	Belongs to the 'phage' integrase family
D0871_26315	COG5492	domain, Protein
D0871_26315	COG4932	domain protein
D0871_26335	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
D0871_26350	COG0739	heme binding
D0871_26535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
D0871_26560	COG2801	Transposase and inactivated derivatives
D0871_26660	COG2948	multi-organism process
D0871_26670	COG3504	Conjugal transfer protein
D0871_26690	COG4962	Type ii secretion system protein e
D0871_26700	COG3451	type IV secretory pathway VirB4
D0871_26705	COG5268	conjugation
D0871_26735	COG1192	Involved in chromosome partitioning