locus-tag	class	description
K9N54_00010	COG0366	Alpha amylase catalytic
K9N54_00015	COG0751	glycine-tRNA ligase activity
K9N54_00020	COG0752	glycyl-tRNA synthetase alpha subunit
K9N54_00025	COG2119	membrane
K9N54_00035	COG0425	Belongs to the sulfur carrier protein TusA family
K9N54_00050	COG0604	alcohol dehydrogenase
K9N54_00055	COG0183	Belongs to the thiolase family
K9N54_00060	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9N54_00060	COG1024	Enoyl-CoA hydratase
K9N54_00065	COG1739	Uncharacterized protein family UPF0029
K9N54_00070	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K9N54_00110	COG0583	DNA-binding transcription factor activity
K9N54_00115	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K9N54_00120	COG2960	long-chain fatty acid transporting porin activity
K9N54_00125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9N54_00130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9N54_00180	COG4172	Belongs to the ABC transporter superfamily
K9N54_00185	COG0747	negative chemotaxis
K9N54_00190	COG0601	transmembrane transport
K9N54_00195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K9N54_00230	COG1609	Transcriptional regulator
K9N54_00235	COG0583	DNA-binding transcription factor activity
K9N54_00250	COG0129	dihydroxy-acid dehydratase activity
K9N54_00255	COG3265	gluconokinase activity
K9N54_00260	COG2610	gluconate transmembrane transporter activity
K9N54_00265	COG0800	Aldolase
K9N54_00270	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
K9N54_00275	COG0583	DNA-binding transcription factor activity
K9N54_00280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9N54_00285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
K9N54_00290	COG0339	signal peptide processing
K9N54_00295	COG1522	sequence-specific DNA binding
K9N54_00300	COG5002	protein histidine kinase activity
K9N54_00300	COG5001	Diguanylate cyclase
K9N54_00305	COG0742	ribosomal rna small subunit methyltransferase
K9N54_00320	COG0589	response to stress
K9N54_00325	COG1528	Iron-storage protein
K9N54_00335	COG2081	HI0933 family
K9N54_00345	COG2823	Periplasmic or secreted lipoprotein
K9N54_00395	COG0628	permease
K9N54_00410	COG1322	Protein conserved in bacteria
K9N54_00415	COG2226	methyltransferase
K9N54_00420	COG3165	ubiquinone biosynthetic process from chorismate
K9N54_00425	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K9N54_00430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K9N54_00435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K9N54_00440	COG0805	protein transport
K9N54_00445	COG0084	hydrolase, TatD family'
K9N54_00465	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K9N54_00465	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K9N54_00470	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K9N54_00500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K9N54_00510	COG2204	response regulator
K9N54_00515	COG3852	Histidine kinase
K9N54_00525	COG0174	glutamine synthetase
K9N54_00530	COG1217	gtp-binding protein TYPA
K9N54_00545	COG1295	ribonuclease BN
K9N54_00550	COG1490	D-aminoacyl-tRNA deacylase activity
K9N54_00555	COG0456	acetyltransferase
K9N54_00565	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
K9N54_00570	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
K9N54_00575	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K9N54_00580	COG3031	protein transport across the cell outer membrane
K9N54_00590	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K9N54_00595	COG1459	type II secretion system
K9N54_00600	COG2165	general secretion pathway protein
K9N54_00605	COG2165	general secretion pathway protein
K9N54_00610	COG2165	general secretion pathway protein
K9N54_00615	COG4795	General secretion pathway protein
K9N54_00620	COG3156	type II secretion system protein K
K9N54_00625	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
K9N54_00630	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
K9N54_00640	COG1218	3'(2'),5'-bisphosphate nucleotidase
K9N54_00645	COG0494	nUDIX hydrolase
K9N54_00650	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K9N54_00650	COG0316	Belongs to the HesB IscA family
K9N54_00655	COG1040	competence protein
K9N54_00660	COG0596	Alpha beta hydrolase
K9N54_00670	COG2183	response to ionizing radiation
K9N54_00680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9N54_00700	COG2233	PERMEase
K9N54_00705	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K9N54_00710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9N54_00715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K9N54_00720	COG1758	RNA polymerase activity
K9N54_00725	COG0194	GDP metabolic process
K9N54_00740	COG0848	biopolymer transport protein
K9N54_00745	COG0811	peptide transport
K9N54_00765	COG4174	ABC transporter (Permease)
K9N54_00770	COG4239	(ABC) transporter, permease
K9N54_00775	COG0747	negative chemotaxis
K9N54_00780	COG0444	Belongs to the ABC transporter superfamily
K9N54_00785	COG4608	Belongs to the ABC transporter superfamily
K9N54_00840	COG1561	YicC-like family, N-terminal region
K9N54_00845	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K9N54_00850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K9N54_00855	COG1560	Kdo2-lipid A biosynthetic process
K9N54_00860	COG1309	transcriptional regulator
K9N54_00865	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K9N54_00875	COG2003	Belongs to the UPF0758 family
K9N54_00880	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K9N54_00895	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K9N54_00910	COG0438	transferase activity, transferring glycosyl groups
K9N54_00915	COG0463	Glycosyl transferase, family 2
K9N54_00920	COG0859	PFAM glycosyl transferase family 9
K9N54_00925	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K9N54_00930	COG3642	lipopolysaccharide core region biosynthetic process
K9N54_00950	COG0110	maltose O-acetyltransferase activity
K9N54_00955	COG2030	dehydratase
K9N54_00975	COG0438	transferase activity, transferring glycosyl groups
K9N54_00975	COG0297	glycogen (starch) synthase activity
K9N54_00985	COG1519	Transferase
K9N54_00990	COG0859	PFAM glycosyl transferase family 9
K9N54_00995	COG1560	Kdo2-lipid A biosynthetic process
K9N54_01005	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9N54_01055	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K9N54_01065	COG0110	maltose O-acetyltransferase activity
K9N54_01070	COG1215	transferase activity, transferring glycosyl groups
K9N54_01090	COG0438	transferase activity, transferring glycosyl groups
K9N54_01110	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K9N54_01155	COG2801	Transposase and inactivated derivatives
K9N54_01165	COG0149	triose-phosphate isomerase activity
K9N54_01190	COG1494	fructose-1,6-bisphosphatase
K9N54_01195	COG3074	FtsZ-dependent cytokinesis
K9N54_01200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K9N54_01205	COG1575	Belongs to the MenA family. Type 1 subfamily
K9N54_01235	COG2003	Belongs to the UPF0758 family
K9N54_01250	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
K9N54_01255	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
K9N54_01265	COG1609	Transcriptional regulator
K9N54_01270	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K9N54_01275	COG0254	rRNA binding
K9N54_01285	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K9N54_01290	COG0088	Forms part of the polypeptide exit tunnel
K9N54_01300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K9N54_01305	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K9N54_01310	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K9N54_01315	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K9N54_01325	COG0255	Belongs to the universal ribosomal protein uL29 family
K9N54_01330	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K9N54_01335	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K9N54_01340	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K9N54_01345	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K9N54_01350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K9N54_01355	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K9N54_01360	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K9N54_01375	COG1841	ribosomal large subunit assembly
K9N54_01380	COG0200	Binds to the 23S rRNA
K9N54_01385	COG0201	protein transport
K9N54_01390	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K9N54_01395	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K9N54_01400	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K9N54_01410	COG0202	RNA polymerase activity
K9N54_01415	COG0203	ribosomal protein L17
K9N54_01425	COG0545	Peptidyl-prolyl cis-trans isomerase
K9N54_01435	COG2153	protein acetylation
K9N54_01440	COG0513	Belongs to the DEAD box helicase family
K9N54_01450	COG0737	Belongs to the 5'-nucleotidase family
K9N54_01455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K9N54_01455	COG1648	precorrin-2 dehydrogenase activity
K9N54_01460	COG0175	sulfate reduction
K9N54_01465	COG2895	sulfate adenylyltransferase (ATP) activity
K9N54_01470	COG3273	potassium ion transport
K9N54_01470	COG0471	metal ion transport
K9N54_01475	COG0529	Catalyzes the synthesis of activated sulfate
K9N54_01495	COG4181	ATPase activity
K9N54_01510	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
K9N54_01520	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9N54_01525	COG0729	surface antigen
K9N54_01535	COG2105	PFAM AIG2 family protein
K9N54_01545	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K9N54_01550	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
K9N54_01555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K9N54_01560	COG0163	prenyltransferase activity
K9N54_01565	COG4143	(ABC) transporter
K9N54_01570	COG1178	ABC-type Fe3 transport system permease component
K9N54_01575	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
K9N54_01590	COG2358	TRAP transporter, solute receptor (TAXI family
K9N54_01600	COG0039	L-malate dehydrogenase activity
K9N54_01610	COG0142	geranyltranstransferase activity
K9N54_01615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K9N54_01625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K9N54_01630	COG2966	Psort location CytoplasmicMembrane, score
K9N54_01645	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K9N54_01650	COG2967	ApaG domain
K9N54_01655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K9N54_01660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
K9N54_01665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9N54_01670	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
K9N54_01675	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
K9N54_01685	COG0066	3-isopropylmalate dehydratase activity
K9N54_01690	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K9N54_01695	COG0473	3-isopropylmalate dehydrogenase activity
K9N54_01700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K9N54_01720	COG0583	DNA-binding transcription factor activity
K9N54_01725	COG1022	Amp-dependent synthetase and ligase
K9N54_01730	COG0028	Belongs to the TPP enzyme family
K9N54_01735	COG0440	acetolactate synthase activity
K9N54_01750	COG0469	pyruvate kinase activity
K9N54_01755	COG1349	DNA-binding transcription factor activity
K9N54_01760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K9N54_01775	COG5002	protein histidine kinase activity
K9N54_01780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9N54_01785	COG3722	fumarate hydratase activity
K9N54_01790	COG0246	Mannitol dehydrogenase
K9N54_01795	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9N54_01795	COG2213	PTS system mannitol-specific
K9N54_01825	COG1464	Belongs to the NlpA lipoprotein family
K9N54_01870	COG0732	type I restriction modification DNA specificity domain
K9N54_01920	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
K9N54_02020	COG0358	DNA primase activity
K9N54_02025	COG1610	YqeY-like protein
K9N54_02030	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K9N54_02035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K9N54_02040	COG0596	Alpha beta hydrolase
K9N54_02045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
K9N54_02050	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
K9N54_02055	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K9N54_02060	COG1968	undecaprenyl-diphosphatase activity
K9N54_02065	COG0617	tRNA 3'-terminal CCA addition
K9N54_02070	COG3267	Type II secretory pathway component ExeA
K9N54_02070	COG3409	Peptidoglycan-binding domain 1 protein
K9N54_02080	COG4991	sh3 domain protein
K9N54_02085	COG0306	phosphate transporter
K9N54_02090	COG1392	Phosphate transport regulator
K9N54_02095	COG3025	triphosphatase activity
K9N54_02110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K9N54_02115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
K9N54_02115	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
K9N54_02120	COG1538	Outer membrane efflux protein
K9N54_02125	COG0494	nUDIX hydrolase
K9N54_02130	COG3151	Protein conserved in bacteria
K9N54_02140	COG3150	esterase
K9N54_02150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K9N54_02155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K9N54_02165	COG3105	Protein conserved in bacteria
K9N54_02170	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
K9N54_02175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K9N54_02180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K9N54_02185	COG0723	plastoquinol--plastocyanin reductase activity
K9N54_02190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K9N54_02195	COG2857	Cytochrome c1
K9N54_02200	COG0625	glutathione transferase activity
K9N54_02205	COG2969	positive regulation of protein catabolic process
K9N54_02210	COG2823	Periplasmic or secreted lipoprotein
K9N54_02215	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
K9N54_02220	COG0792	nuclease activity
K9N54_02230	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K9N54_02240	COG0275	rRNA processing
K9N54_02245	COG3116	cell division
K9N54_02250	COG0768	penicillin binding
K9N54_02255	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K9N54_02260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K9N54_02265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K9N54_02270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K9N54_02275	COG0772	Belongs to the SEDS family
K9N54_02280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K9N54_02285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K9N54_02290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K9N54_02295	COG0849	cell division
K9N54_02300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K9N54_02305	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
K9N54_02315	COG0653	protein targeting
K9N54_02320	COG0494	nUDIX hydrolase
K9N54_02325	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K9N54_02330	COG0505	Belongs to the CarA family
K9N54_02335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K9N54_02350	COG0730	response to heat
K9N54_02355	COG0583	DNA-binding transcription factor activity
K9N54_02360	COG2860	membrane
K9N54_02365	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K9N54_02375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K9N54_02385	COG0493	'glutamate synthase
K9N54_02390	COG0069	glutamate synthase activity
K9N54_02390	COG0067	glutamate synthase
K9N54_02390	COG0070	glutamate synthase
K9N54_02400	COG0067	glutamate synthase
K9N54_02400	COG0069	glutamate synthase activity
K9N54_02400	COG0070	glutamate synthase
K9N54_02405	COG1242	4 iron, 4 sulfur cluster binding
K9N54_02410	COG2203	Gaf domain
K9N54_02410	COG3706	GGDEF domain
K9N54_02410	COG5001	Diguanylate cyclase
K9N54_02410	COG4251	negative regulation of phosphorylation
K9N54_02415	COG5002	protein histidine kinase activity
K9N54_02415	COG2198	Histidine kinase
K9N54_02415	COG0784	Response regulator, receiver
K9N54_02425	COG0745	RESPONSE REGULATOR receiver
K9N54_02435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K9N54_02450	COG0083	homoserine kinase activity
K9N54_02455	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K9N54_02460	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
K9N54_02465	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
K9N54_02470	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
K9N54_02485	COG1115	amino acid carrier protein
K9N54_02490	COG3022	response to hydroperoxide
K9N54_02495	COG0513	Belongs to the DEAD box helicase family
K9N54_02500	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
K9N54_02510	COG0716	FMN binding
K9N54_02515	COG4974	Belongs to the 'phage' integrase family
K9N54_02520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9N54_02525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K9N54_02535	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
K9N54_02550	COG0667	Aldo Keto reductase
K9N54_02560	COG3066	DNA modification
K9N54_02565	COG0494	nUDIX hydrolase
K9N54_02575	COG0730	response to heat
K9N54_02580	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K9N54_02585	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
K9N54_02595	COG1283	sodium-dependent phosphate transmembrane transporter activity
K9N54_02600	COG0583	DNA-binding transcription factor activity
K9N54_02605	COG0640	Transcriptional regulator
K9N54_02610	COG0268	Binds directly to 16S ribosomal RNA
K9N54_02615	COG0728	peptidoglycan biosynthetic process
K9N54_02620	COG0196	riboflavin kinase activity
K9N54_02625	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K9N54_02630	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K9N54_02635	COG1047	Peptidyl-prolyl cis-trans
K9N54_02640	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K9N54_02645	COG3279	Response regulator of the LytR AlgR family
K9N54_02650	COG3275	phosphorelay sensor kinase activity
K9N54_02655	COG1966	Carbon starvation protein
K9N54_02670	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K9N54_02675	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
K9N54_02680	COG1472	Belongs to the glycosyl hydrolase 3 family
K9N54_02685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K9N54_02690	COG0287	Prephenate dehydrogenase
K9N54_02690	COG1605	Chorismate mutase
K9N54_02695	COG0739	heme binding
K9N54_02705	COG0488	(ABC) transporter
K9N54_02715	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
K9N54_02720	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
K9N54_02725	COG0077	Prephenate dehydratase
K9N54_02725	COG1605	Chorismate mutase
K9N54_02730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K9N54_02735	COG0739	heme binding
K9N54_02735	COG1196	nuclear chromosome segregation
K9N54_02735	COG0741	lytic transglycosylase activity
K9N54_02740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9N54_02745	COG0564	pseudouridine synthase activity
K9N54_02755	COG0542	response to heat
K9N54_02810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K9N54_02815	COG0826	peptidase U32
K9N54_02820	COG2974	May be involved in recombination
K9N54_02825	COG0745	RESPONSE REGULATOR receiver
K9N54_02830	COG5002	protein histidine kinase activity
K9N54_02840	COG0248	Ppx GppA phosphatase
K9N54_02845	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K9N54_02855	COG0581	inorganic phosphate transmembrane transporter activity
K9N54_02860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K9N54_02865	COG0704	Plays a role in the regulation of phosphate uptake
K9N54_02875	COG3142	Participates in the control of copper homeostasis
K9N54_02880	COG0450	alkyl hydroperoxide reductase
K9N54_02885	COG0583	DNA-binding transcription factor activity
K9N54_02890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K9N54_02900	COG0517	IMP dehydrogenase activity
K9N54_02910	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K9N54_02915	COG0343	queuine tRNA-ribosyltransferase activity
K9N54_02920	COG1862	Preprotein translocase
K9N54_02925	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K9N54_02930	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K9N54_02935	COG0483	inositol monophosphate 1-phosphatase activity
K9N54_02950	COG1104	cysteine desulfurase activity
K9N54_02955	COG0822	iron-sulfur transferase activity
K9N54_02965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
K9N54_02970	COG0443	Heat shock 70 kDa protein
K9N54_02975	COG0633	Ferredoxin
K9N54_02980	COG2975	iron-sulfur cluster assembly
K9N54_02985	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K9N54_02990	COG0105	UTP biosynthetic process
K9N54_02995	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K9N54_03005	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
K9N54_03010	COG0124	histidyl-tRNA synthetase
K9N54_03015	COG2976	Protein conserved in bacteria
K9N54_03020	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9N54_03025	COG1160	GTP binding
K9N54_03040	COG1570	exodeoxyribonuclease VII activity
K9N54_03045	COG0517	IMP dehydrogenase activity
K9N54_03045	COG0516	GMP reductase activity
K9N54_03050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K9N54_03050	COG0519	Catalyzes the synthesis of GMP from XMP
K9N54_03055	COG1757	Na H antiporter
K9N54_03065	COG1584	GPR1 FUN34 yaaH family protein
K9N54_03075	COG1115	amino acid carrier protein
K9N54_03105	COG2873	o-acetylhomoserine
K9N54_03110	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K9N54_03130	COG3153	acetyltransferase
K9N54_03130	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9N54_03135	COG0583	DNA-binding transcription factor activity
K9N54_03175	COG2003	Belongs to the UPF0758 family
K9N54_03230	COG3293	Transposase
K9N54_03240	COG1609	Transcriptional regulator
K9N54_03250	COG2182	Extracellular solute-binding protein
K9N54_03255	COG1175	transmembrane transport
K9N54_03260	COG3833	ABC-type maltose transport systems, permease component
K9N54_03270	COG1874	Beta-galactosidase
K9N54_03275	COG4580	involved in the transport of maltose and maltodextrins
K9N54_03300	COG0582	viral genome integration into host DNA
K9N54_03320	COG3501	Rhs element vgr protein
K9N54_03365	COG0582	viral genome integration into host DNA
K9N54_03375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K9N54_03380	COG2867	negative regulation of translational initiation
K9N54_03385	COG2914	Belongs to the UPF0125 (RnfH) family
K9N54_03390	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9N54_03395	COG0497	DNA recombination
K9N54_03405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K9N54_03410	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K9N54_03420	COG0443	Heat shock 70 kDa protein
K9N54_03425	COG0484	heat shock protein binding
K9N54_03455	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
K9N54_03465	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
K9N54_03470	COG0047	phosphoribosylformylglycinamidine synthase activity
K9N54_03470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K9N54_03495	COG2195	Cleaves the N-terminal amino acid of tripeptides
K9N54_03500	COG2252	PERMEase
K9N54_03505	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
K9N54_03510	COG1073	alpha beta
K9N54_03520	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K9N54_03525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K9N54_03530	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K9N54_03535	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9N54_03535	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9N54_03555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K9N54_03560	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K9N54_03565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K9N54_03570	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K9N54_03575	COG0142	geranyltranstransferase activity
K9N54_03580	COG1722	exodeoxyribonuclease VII activity
K9N54_03585	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K9N54_03590	COG2885	chlorophyll binding
K9N54_03595	COG0301	tRNA thio-modification
K9N54_03595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K9N54_03600	COG0583	DNA-binding transcription factor activity
K9N54_03610	COG2363	Small membrane protein
K9N54_03615	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
K9N54_03625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K9N54_03630	COG1611	Belongs to the LOG family
K9N54_03645	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K9N54_03645	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K9N54_03655	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
K9N54_03660	COG1464	Belongs to the NlpA lipoprotein family
K9N54_03665	COG2011	ABC-type metal ion transport system permease component
K9N54_03670	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K9N54_03675	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K9N54_03685	COG1263	PTS System
K9N54_03685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K9N54_03690	COG0366	Alpha amylase catalytic
K9N54_03705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K9N54_03710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K9N54_03715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K9N54_03720	COG0321	lipoyl(octanoyl) transferase activity
K9N54_03725	COG2921	Belongs to the UPF0250 family
K9N54_03730	COG1686	Belongs to the peptidase S11 family
K9N54_03735	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K9N54_03740	COG0772	Belongs to the SEDS family
K9N54_03745	COG0768	penicillin binding
K9N54_03750	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K9N54_03755	COG0799	negative regulation of ribosome biogenesis
K9N54_03760	COG1466	dna polymerase III delta subunit
K9N54_03765	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
K9N54_03770	COG0495	leucyl-tRNA aminoacylation
K9N54_03775	COG2888	peptidyl-tyrosine sulfation
K9N54_03780	COG0815	Transfers the fatty acyl group on membrane lipoproteins
K9N54_03785	COG4535	Mg2 and Co2 transporter CorC
K9N54_03790	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K9N54_03795	COG1702	phosphate starvation-inducible protein PhoH
K9N54_03800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K9N54_03805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9N54_03920	COG0012	GTP binding
K9N54_03925	COG0193	aminoacyl-tRNA hydrolase activity
K9N54_03930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K9N54_03935	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K9N54_03940	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
K9N54_03945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
K9N54_03950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K9N54_03955	COG2890	protein-(glutamine-N5) methyltransferase activity
K9N54_03960	COG3094	Invasion gene expression up-regulator, SirB
K9N54_03965	COG2912	Transglutaminase-like superfamily
K9N54_03970	COG2877	3-deoxy-8-phosphooctulonate synthase activity
K9N54_03975	COG0737	Belongs to the 5'-nucleotidase family
K9N54_03985	COG1187	pseudouridine synthase activity
K9N54_03990	COG2840	Smr protein MutS2
K9N54_04025	COG2217	Heavy metal translocating P-type atpase
K9N54_04025	COG2608	mercury ion transmembrane transporter activity
K9N54_04035	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
K9N54_04040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9N54_04090	COG0835	chemotaxis
K9N54_04090	COG0784	Response regulator, receiver
K9N54_04095	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K9N54_04100	COG1815	bacterial-type flagellum-dependent cell motility
K9N54_04105	COG1558	bacterial-type flagellum-dependent cell motility
K9N54_04115	COG1749	Flagellar hook protein flgE
K9N54_04120	COG4787	bacterial-type flagellum-dependent cell motility
K9N54_04130	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
K9N54_04135	COG1706	bacterial-type flagellum-dependent cell motility
K9N54_04140	COG3951	Flagellar rod assembly protein muramidase FlgJ
K9N54_04140	COG1705	Flagellar rod assembly protein muramidase FlgJ
K9N54_04150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K9N54_04155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K9N54_04160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K9N54_04165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K9N54_04170	COG2190	(PTS) system
K9N54_04175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K9N54_04180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9N54_04185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K9N54_04190	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
K9N54_04195	COG3115	cell septum assembly
K9N54_04200	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K9N54_04220	COG0330	HflC and HflK could
K9N54_04225	COG3118	belongs to the thioredoxin family
K9N54_04230	COG0300	oxidoreductase activity
K9N54_04235	COG1090	epimerase
K9N54_04260	COG0622	Phosphoesterase
K9N54_04280	COG3710	Transcriptional regulator
K9N54_04285	COG0326	Molecular chaperone. Has ATPase activity
K9N54_04290	COG0563	adenylate kinase activity
K9N54_04295	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K9N54_04300	COG3104	oligopeptide transport
K9N54_04305	COG0250	Participates in transcription elongation, termination and antitermination
K9N54_04310	COG0367	asparagine synthase
K9N54_04315	COG4651	solute:proton antiporter activity
K9N54_04315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K9N54_04320	COG1846	Transcriptional regulator
K9N54_04320	COG1940	carbohydrate kinase activity
K9N54_04325	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
K9N54_04330	COG1263	PTS System
K9N54_04330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K9N54_04335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9N54_04340	COG0735	belongs to the Fur family
K9N54_04360	COG0596	Alpha beta hydrolase
K9N54_04365	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
K9N54_04370	COG0033	Phosphoglucomutase
K9N54_04380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K9N54_04395	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
K9N54_04400	COG1053	succinate dehydrogenase
K9N54_04405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K9N54_04410	COG0567	Dehydrogenase, E1 component
K9N54_04415	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9N54_04420	COG0045	succinate-CoA ligase (ADP-forming) activity
K9N54_04430	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K9N54_04435	COG1121	(ABC) transporter
K9N54_04440	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
K9N54_04445	COG4977	sequence-specific DNA binding
K9N54_04450	COG1918	ferrous iron import across plasma membrane
K9N54_04470	COG0018	arginyl-trna synthetase
K9N54_04475	COG3102	Protein conserved in bacteria
K9N54_04480	COG0788	formyltetrahydrofolate deformylase activity
K9N54_04485	COG1199	ATP-dependent helicase activity
K9N54_04490	COG1214	PFAM Peptidase M22, glycoprotease
K9N54_04505	COG2267	carboxylic ester hydrolase activity
K9N54_04510	COG0318	PFAM AMP-dependent synthetase and ligase
K9N54_04515	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K9N54_04520	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
K9N54_04525	COG2894	cell division
K9N54_04530	COG0850	regulation of cytokinetic process
K9N54_04535	COG3100	YcgL domain-containing protein
K9N54_04540	COG2951	lytic endotransglycosylase activity
K9N54_04545	COG0583	DNA-binding transcription factor activity
K9N54_04550	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K9N54_04555	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K9N54_04575	COG1028	Short-chain dehydrogenase reductase Sdr
K9N54_04585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K9N54_04610	COG2986	histidine ammonia-lyase
K9N54_04615	COG1216	Glycosyl transferase, family 2
K9N54_04620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K9N54_04635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K9N54_04640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K9N54_04675	COG1253	flavin adenine dinucleotide binding
K9N54_04680	COG0513	Belongs to the DEAD box helicase family
K9N54_04685	COG0569	domain protein
K9N54_04690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K9N54_04705	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
K9N54_04710	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K9N54_04715	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K9N54_04720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K9N54_04730	COG2204	response regulator
K9N54_04745	COG0544	peptidyl-prolyl cis-trans isomerase activity
K9N54_04755	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K9N54_04760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K9N54_04765	COG0776	regulation of translation
K9N54_04770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9N54_04775	COG1555	photosystem II stabilization
K9N54_04790	COG0232	Belongs to the dGTPase family. Type 2 subfamily
K9N54_04795	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
K9N54_04800	COG0436	Aminotransferase
K9N54_04805	COG1169	isochorismate synthase
K9N54_04810	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
K9N54_04815	COG0596	Alpha beta hydrolase
K9N54_04820	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K9N54_04840	COG2855	membrane
K9N54_04845	COG0477	Major facilitator Superfamily
K9N54_04895	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9N54_04920	COG1522	sequence-specific DNA binding
K9N54_04930	COG1946	Acyl-CoA thioesterase
K9N54_04935	COG3126	Type III secretion system lipoprotein chaperone (YscW)
K9N54_04950	COG2199	diguanylate cyclase activity
K9N54_05015	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K9N54_05070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9N54_05075	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
K9N54_05080	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
K9N54_05085	COG0517	IMP dehydrogenase activity
K9N54_05085	COG0516	GMP reductase activity
K9N54_05110	COG0537	adenosine 5'-monophosphoramidase activity
K9N54_05135	COG3150	esterase
K9N54_05140	COG1252	NADH dehydrogenase
K9N54_05155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K9N54_05165	COG4591	ABC-type transport system involved in lipoprotein release permease component
K9N54_05170	COG1136	(ABC) transporter
K9N54_05175	COG4591	ABC-type transport system involved in lipoprotein release permease component
K9N54_05185	COG2333	competence protein COMEC
K9N54_05185	COG0658	competence protein
K9N54_05190	COG1132	(ABC) transporter
K9N54_05195	COG1663	tetraacyldisaccharide 4'-kinase activity
K9N54_05205	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
K9N54_05210	COG2719	SpoVR family
K9N54_05215	COG2718	Belongs to the UPF0229 family
K9N54_05220	COG2766	serine protein kinase
K9N54_05225	COG3013	Belongs to the UPF0304 family
K9N54_05235	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K9N54_05245	COG1882	Formate acetyltransferase
K9N54_05285	COG0708	Exodeoxyribonuclease III
K9N54_05295	COG3923	Primosomal replication protein n
K9N54_05300	COG0730	response to heat
K9N54_05305	COG1199	ATP-dependent helicase activity
K9N54_05315	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
K9N54_05320	COG1187	pseudouridine synthase activity
K9N54_05330	COG1278	Cold shock
K9N54_05335	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K9N54_05340	COG0542	response to heat
K9N54_05350	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K9N54_05355	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
K9N54_05360	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K9N54_05370	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K9N54_05380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K9N54_05385	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K9N54_05390	COG0297	glycogen (starch) synthase activity
K9N54_05410	COG3070	regulator of competence-specific genes
K9N54_05415	COG1609	Transcriptional regulator
K9N54_05420	COG3381	protein complex oligomerization
K9N54_05425	COG0745	RESPONSE REGULATOR receiver
K9N54_05430	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K9N54_05435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K9N54_05440	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
K9N54_05445	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
K9N54_05450	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
K9N54_05470	COG4067	protein conserved in archaea
K9N54_05470	COG0189	ligase activity
K9N54_05475	COG0500	methyltransferase
K9N54_05480	COG4106	trans-aconitate 2-methyltransferase activity
K9N54_05485	COG1801	Protein of unknown function DUF72
K9N54_05490	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K9N54_05495	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
K9N54_05500	COG0840	transmembrane signaling receptor activity
K9N54_05505	COG0632	four-way junction helicase activity
K9N54_05510	COG2255	four-way junction helicase activity
K9N54_05515	COG1271	oxidase subunit
K9N54_05520	COG1294	oxidase, subunit
K9N54_05525	COG4890	Cyd operon protein YbgT
K9N54_05535	COG0824	Thioesterase
K9N54_05540	COG0811	peptide transport
K9N54_05555	COG0823	Involved in the tonB-independent uptake of proteins
K9N54_05560	COG2885	chlorophyll binding
K9N54_05565	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
K9N54_05570	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K9N54_05590	COG0754	glutathionylspermidine amidase activity
K9N54_05600	COG0784	Response regulator, receiver
K9N54_05600	COG5002	protein histidine kinase activity
K9N54_05675	COG0840	transmembrane signaling receptor activity
K9N54_05680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9N54_05685	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9N54_05735	COG0583	DNA-binding transcription factor activity
K9N54_05745	COG0686	Belongs to the AlaDH PNT family
K9N54_05755	COG1674	ftsk spoiiie
K9N54_05760	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K9N54_05765	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K9N54_05770	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K9N54_05785	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K9N54_05790	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K9N54_05795	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
K9N54_05800	COG0156	8-amino-7-oxononanoate synthase activity
K9N54_05810	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
K9N54_05820	COG0501	Belongs to the peptidase M48B family
K9N54_05830	COG0300	oxidoreductase activity
K9N54_05845	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K9N54_05865	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K9N54_05870	COG2915	High frequency lysogenization protein hflD homolog
K9N54_05875	COG0482	sulfurtransferase activity
K9N54_05885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K9N54_05895	COG1757	Na H antiporter
K9N54_05910	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K9N54_05915	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K9N54_05920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K9N54_05925	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
K9N54_05925	COG0131	Imidazoleglycerol-phosphate dehydratase
K9N54_05930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K9N54_05935	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K9N54_05940	COG0107	imidazoleglycerol-phosphate synthase activity
K9N54_05945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K9N54_05945	COG0140	phosphoribosyl-ATP diphosphatase activity
K9N54_05950	COG3012	SEC-C Motif Domain Protein
K9N54_05955	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
K9N54_05960	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9N54_05965	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K9N54_05970	COG0215	cysteine-tRNA ligase activity
K9N54_05975	COG1435	thymidine kinase activity
K9N54_05980	COG1434	Gram-negative-bacterium-type cell wall biogenesis
K9N54_06005	COG2116	formate transmembrane transporter activity
K9N54_06015	COG0390	transport system, permease component
K9N54_06020	COG4459	periplasmic nitrate reductase
K9N54_06025	COG3005	denitrification pathway
K9N54_06030	COG0243	molybdopterin cofactor binding
K9N54_06045	COG1227	inorganic diphosphatase activity
K9N54_06055	COG4172	Belongs to the ABC transporter superfamily
K9N54_06065	COG4171	peptide transport system, permease
K9N54_06080	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
K9N54_06085	COG1842	Phage shock protein A
K9N54_06095	COG1983	PspC domain protein
K9N54_06100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9N54_06115	COG2818	Glycosylase
K9N54_06120	COG5380	lipid catabolic process
K9N54_06125	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
K9N54_06130	COG0626	cystathionine gamma-synthase activity
K9N54_06140	COG0733	neurotransmitter:sodium symporter activity
K9N54_06150	COG0564	pseudouridine synthase activity
K9N54_06160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9N54_06165	COG1151	hydroxylamine reductase activity
K9N54_06170	COG3604	Transcriptional regulator
K9N54_06180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K9N54_06185	COG4136	ATPase activity
K9N54_06190	COG4135	transport system, permease component
K9N54_06195	COG4134	Bacterial extracellular solute-binding protein
K9N54_06200	COG0398	Pfam SNARE associated Golgi protein
K9N54_06210	COG0493	'glutamate synthase
K9N54_06235	COG3313	Fe-S protein
K9N54_06260	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K9N54_06280	COG1061	Type III restriction enzyme res subunit
K9N54_06285	COG1187	pseudouridine synthase activity
K9N54_06290	COG2814	Major facilitator Superfamily
K9N54_06320	COG3005	denitrification pathway
K9N54_06325	COG0702	epimerase
K9N54_06330	COG0534	Mate efflux family protein
K9N54_06335	COG4181	ATPase activity
K9N54_06350	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K9N54_06365	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K9N54_06370	COG2985	domain, Protein
K9N54_06370	COG3273	potassium ion transport
K9N54_06375	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K9N54_06385	COG1737	Transcriptional regulator
K9N54_06390	COG0076	glutamate decarboxylase activity
K9N54_06400	COG2431	L-lysine efflux transmembrane transporter activity
K9N54_06410	COG3070	regulator of competence-specific genes
K9N54_06425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9N54_06425	COG4191	Histidine kinase
K9N54_06435	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K9N54_06440	COG3048	D-serine ammonia-lyase activity
K9N54_06445	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
K9N54_06450	COG4988	ABC transporter
K9N54_06455	COG0492	ferredoxin-NADP+ reductase activity
K9N54_06480	COG0471	metal ion transport
K9N54_06485	COG2949	membrane
K9N54_06490	COG0281	malic enzyme
K9N54_06495	COG1643	Atp-dependent helicase
K9N54_06500	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
K9N54_06515	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K9N54_06550	COG0247	lactate metabolic process
K9N54_06550	COG0277	FAD linked oxidase domain protein
K9N54_06565	COG2986	histidine ammonia-lyase
K9N54_06570	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
K9N54_06575	COG0010	Belongs to the arginase family
K9N54_06580	COG1228	amidohydrolase
K9N54_06585	COG2188	Transcriptional regulator
K9N54_06600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K9N54_06610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K9N54_06620	COG0393	Putative heavy-metal-binding
K9N54_06650	COG3706	GGDEF domain
K9N54_06655	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K9N54_06660	COG0072	phenylalanine-tRNA ligase activity
K9N54_06660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9N54_06670	COG0776	regulation of translation
K9N54_06680	COG0500	methyltransferase
K9N54_06685	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
K9N54_06690	COG0295	cytidine deaminase activity
K9N54_06695	COG1346	cytolysis
K9N54_06700	COG1380	Effector of murein hydrolase LrgA
K9N54_06705	COG2925	Exonuclease
K9N54_06710	COG1823	symporter activity
K9N54_06715	COG0702	epimerase
K9N54_06720	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K9N54_06725	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
K9N54_06735	COG2062	phosphohistidine phosphatase, SixA
K9N54_06745	COG2988	succinylglutamate desuccinylase activity
K9N54_06750	COG4139	cobalamin transport
K9N54_06755	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
K9N54_06775	COG0583	DNA-binding transcription factor activity
K9N54_06785	COG1451	nucleotide metabolic process
K9N54_06790	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
K9N54_06820	COG3938	Belongs to the proline racemase family
K9N54_06835	COG2423	ornithine cyclodeaminase activity
K9N54_06840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9N54_06845	COG3842	ATPase activity
K9N54_06850	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9N54_06855	COG1177	transmembrane transport
K9N54_06865	COG3291	Pkd domain containing protein
K9N54_06880	COG0444	Belongs to the ABC transporter superfamily
K9N54_06885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K9N54_06890	COG0601	transmembrane transport
K9N54_06900	COG2195	Cleaves the N-terminal amino acid of tripeptides
K9N54_06915	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
K9N54_06925	COG0625	glutathione transferase activity
K9N54_06985	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
K9N54_06990	COG0583	DNA-binding transcription factor activity
K9N54_07025	COG0471	metal ion transport
K9N54_07030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9N54_07030	COG4191	Histidine kinase
K9N54_07040	COG5001	Diguanylate cyclase
K9N54_07040	COG3300	MHYT domain
K9N54_07050	COG1280	lysine exporter protein (LysE YggA)
K9N54_07055	COG1328	CTP reductase activity
K9N54_07060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K9N54_07070	COG0861	Integral membrane protein TerC family
K9N54_07075	COG0739	heme binding
K9N54_07095	COG2885	chlorophyll binding
K9N54_07115	COG3501	Rhs element vgr protein
K9N54_07140	COG0515	serine threonine protein kinase
K9N54_07175	COG1522	sequence-specific DNA binding
K9N54_07255	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
K9N54_07265	COG0814	amino acid
K9N54_07285	COG1132	(ABC) transporter
K9N54_07290	COG1132	(ABC) transporter
K9N54_07315	COG0443	Heat shock 70 kDa protein
K9N54_07320	COG0443	Heat shock 70 kDa protein
K9N54_07360	COG0243	molybdopterin cofactor binding
K9N54_07365	COG0437	4 iron, 4 sulfur cluster binding
K9N54_07370	COG3302	dmso reductase anchor subunit
K9N54_07385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K9N54_07390	COG1643	Atp-dependent helicase
K9N54_07405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K9N54_07415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K9N54_07420	COG1215	transferase activity, transferring glycosyl groups
K9N54_07425	COG0438	transferase activity, transferring glycosyl groups
K9N54_07465	COG2204	response regulator
K9N54_07495	COG1793	dna ligase
K9N54_07505	COG0534	Mate efflux family protein
K9N54_07510	COG0307	riboflavin synthase, alpha
K9N54_07520	COG3001	Fructosamine kinase
K9N54_07525	COG2201	protein-glutamate methylesterase activity
K9N54_07530	COG3706	GGDEF domain
K9N54_07540	COG0791	NLP P60 protein
K9N54_07580	COG3148	PFAM DTW domain containing protein
K9N54_07585	COG1940	carbohydrate kinase activity
K9N54_07595	COG0303	'Molybdopterin
K9N54_07600	COG0746	molybdenum cofactor guanylyltransferase activity
K9N54_07605	COG3842	ATPase activity
K9N54_07620	COG2204	response regulator
K9N54_07625	COG4191	Histidine kinase
K9N54_07630	COG0488	(ABC) transporter
K9N54_07635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K9N54_07655	COG3381	protein complex oligomerization
K9N54_07665	COG0243	molybdopterin cofactor binding
K9N54_07665	COG3383	formate dehydrogenase (NAD+) activity
K9N54_07670	COG0437	4 iron, 4 sulfur cluster binding
K9N54_07695	COG0004	ammonium transporteR
K9N54_07705	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K9N54_07710	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K9N54_07720	COG1177	transmembrane transport
K9N54_07730	COG3842	ATPase activity
K9N54_07750	COG0037	tRNA processing
K9N54_07755	COG0589	response to stress
K9N54_07760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9N54_07775	COG2217	Heavy metal translocating P-type atpase
K9N54_07785	COG2010	Cytochrome c
K9N54_07800	COG3278	Belongs to the heme-copper respiratory oxidase family
K9N54_07815	COG0784	Response regulator, receiver
K9N54_07815	COG2205	protein histidine kinase activity
K9N54_07830	COG3120	sequence-specific DNA binding
K9N54_07835	COG1067	ATP-dependent peptidase activity
K9N54_07840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K9N54_07855	COG0488	(ABC) transporter
K9N54_07865	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K9N54_07865	COG0116	Belongs to the methyltransferase superfamily
K9N54_07875	COG0167	dihydroorotate dehydrogenase activity
K9N54_07880	COG2902	Dehydrogenase
K9N54_07890	COG0308	aminopeptidase N
K9N54_07905	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
K9N54_07910	COG1956	GAF domain-containing protein
K9N54_07915	COG1132	(ABC) transporter
K9N54_07920	COG2995	paraquat-inducible protein a
K9N54_07925	COG3008	intermembrane lipid transfer
K9N54_07930	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K9N54_07930	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
K9N54_07950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K9N54_07955	COG1666	GTP binding
K9N54_07965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9N54_07970	COG4597	amino acid ABC transporter
K9N54_07975	COG0765	amino acid transport
K9N54_07980	COG1126	abc transporter atp-binding protein
K9N54_07985	COG0670	Belongs to the BI1 family
K9N54_07995	COG2920	part of a sulfur-relay system
K9N54_08000	COG1254	Belongs to the acylphosphatase family
K9N54_08005	COG0840	transmembrane signaling receptor activity
K9N54_08010	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
K9N54_08050	COG3706	GGDEF domain
K9N54_08055	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K9N54_08060	COG0602	queuosine metabolic process
K9N54_08065	COG0561	phosphatase activity
K9N54_08090	COG2828	Protein conserved in bacteria
K9N54_08100	COG0372	Belongs to the citrate synthase family
K9N54_08105	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K9N54_08135	COG0730	response to heat
K9N54_08155	COG0457	Tetratricopeptide repeat
K9N54_08225	COG4790	Type iii secretion
K9N54_08230	COG4794	Type iii secretion
K9N54_08235	COG4791	protein targeting
K9N54_08240	COG4792	protein secretion
K9N54_08250	COG1073	alpha beta
K9N54_08255	COG1073	alpha beta
K9N54_08470	COG3012	SEC-C Motif Domain Protein
K9N54_08535	COG3423	Transcriptional regulator
K9N54_08565	COG4669	(LipO)protein
K9N54_08635	COG1012	belongs to the aldehyde dehydrogenase family
K9N54_08640	COG3284	Transcriptional regulator
K9N54_08670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
K9N54_08675	COG0363	glucosamine-6-phosphate deaminase activity
K9N54_08680	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K9N54_08880	COG1783	phage Terminase large subunit
K9N54_08895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K9N54_08915	COG1475	DNA binding
K9N54_09050	COG4565	transcriptional regulatory protein
K9N54_09055	COG3290	protein histidine kinase activity
K9N54_09070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9N54_09085	COG1858	cytochrome C peroxidase
K9N54_09090	COG0527	aspartate kinase activity
K9N54_09095	COG0662	Cupin 2, conserved barrel domain protein
K9N54_09100	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K9N54_09105	COG0456	acetyltransferase
K9N54_09110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K9N54_09130	COG4176	ABC-type proline glycine betaine transport system permease component
K9N54_09135	COG2113	Glycine betaine
K9N54_09155	COG1028	Short-chain dehydrogenase reductase Sdr
K9N54_09165	COG0745	RESPONSE REGULATOR receiver
K9N54_09170	COG0642	Histidine kinase
K9N54_09175	COG1368	sulfuric ester hydrolase activity
K9N54_09200	COG1115	amino acid carrier protein
K9N54_09210	COG1280	lysine exporter protein (LysE YggA)
K9N54_09215	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
K9N54_09220	COG1560	Kdo2-lipid A biosynthetic process
K9N54_09225	COG0531	amino acid
K9N54_09235	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
K9N54_09240	COG3063	Type IV pilus biogenesis stability protein PilW
K9N54_09270	COG0110	maltose O-acetyltransferase activity
K9N54_09290	COG2315	Protein conserved in bacteria
K9N54_09295	COG1846	Transcriptional regulator
K9N54_09310	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K9N54_09320	COG2771	luxR family
K9N54_09320	COG2200	EAL domain
K9N54_09325	COG1227	inorganic diphosphatase activity
K9N54_09330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K9N54_09335	COG1012	belongs to the aldehyde dehydrogenase family
K9N54_09340	COG2957	Belongs to the agmatine deiminase family
K9N54_09350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9N54_09355	COG1012	belongs to the aldehyde dehydrogenase family
K9N54_09360	COG1396	sequence-specific DNA binding
K9N54_09360	COG1917	Cupin 2, conserved barrel domain protein
K9N54_09365	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K9N54_09370	COG0174	glutamine synthetase
K9N54_09375	COG1757	Na H antiporter
K9N54_09415	COG2801	Transposase and inactivated derivatives
K9N54_09660	COG1280	lysine exporter protein (LysE YggA)
K9N54_09765	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K9N54_09855	COG1192	Involved in chromosome partitioning
K9N54_09920	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K9N54_09945	COG0456	acetyltransferase
K9N54_09950	COG1335	isochorismatase
K9N54_10135	COG0251	oxidation-reduction process
K9N54_10330	COG2732	(Barnase) inhibitor
K9N54_10420	COG0251	oxidation-reduction process
K9N54_10520	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K9N54_10530	COG3768	UPF0283 membrane protein
K9N54_10535	COG3106	COG3106 Predicted ATPase
K9N54_10550	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K9N54_10555	COG2205	protein histidine kinase activity
K9N54_10555	COG0784	Response regulator, receiver
K9N54_10565	COG0494	nUDIX hydrolase
K9N54_10570	COG0814	amino acid
K9N54_10575	COG1760	l-serine dehydratase
K9N54_10580	COG2200	EAL domain
K9N54_10590	COG0720	synthase
K9N54_10595	COG0840	transmembrane signaling receptor activity
K9N54_10600	COG0017	Asparaginyl-tRNA synthetase
K9N54_10610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9N54_10625	COG1448	Aminotransferase
K9N54_10645	COG0840	transmembrane signaling receptor activity
K9N54_10650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K9N54_10655	COG1846	Transcriptional regulator
K9N54_10680	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K9N54_10695	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9N54_10700	COG3108	Peptidase M15
K9N54_10705	COG2989	Protein conserved in bacteria
K9N54_10730	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K9N54_10740	COG3088	subunit of a heme lyase
K9N54_10740	COG4235	cytochrome complex assembly
K9N54_10750	COG1138	Cytochrome C-type biogenesis protein
K9N54_10755	COG3301	Polysulphide reductase, NrfD
K9N54_10760	COG0437	4 iron, 4 sulfur cluster binding
K9N54_10770	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
K9N54_10790	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K9N54_10795	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K9N54_10800	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K9N54_10825	COG0019	diaminopimelate decarboxylase activity
K9N54_10865	COG0322	excinuclease ABC activity
K9N54_10870	COG2197	response regulator
K9N54_10875	COG0417	DNA replication proofreading
K9N54_10885	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K9N54_10890	COG3099	Belongs to the UPF0263 family
K9N54_10895	COG1187	pseudouridine synthase activity
K9N54_10905	COG0009	L-threonylcarbamoyladenylate synthase
K9N54_10910	COG0613	PHP domain protein
K9N54_10920	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K9N54_10925	COG0512	Glutamine amidotransferase of anthranilate synthase
K9N54_10930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K9N54_10935	COG0134	indole-3-glycerol-phosphate synthase activity
K9N54_10935	COG0135	phosphoribosylanthranilate isomerase activity
K9N54_10940	COG0133	tryptophan synthase activity
K9N54_10945	COG0159	tryptophan synthase activity
K9N54_10950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9N54_10955	COG0318	PFAM AMP-dependent synthetase and ligase
K9N54_10960	COG1301	dicarboxylic acid transport
K9N54_10980	COG2917	probably involved in intracellular septation
K9N54_10990	COG2350	Protein conserved in bacteria
K9N54_11000	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
K9N54_11005	COG0583	DNA-binding transcription factor activity
K9N54_11020	COG2203	Gaf domain
K9N54_11020	COG3706	GGDEF domain
K9N54_11020	COG5001	Diguanylate cyclase
K9N54_11020	COG4251	negative regulation of phosphorylation
K9N54_11025	COG1032	radical SAM domain protein
K9N54_11030	COG0840	transmembrane signaling receptor activity
K9N54_11035	COG0745	RESPONSE REGULATOR receiver
K9N54_11040	COG5002	protein histidine kinase activity
K9N54_11040	COG3850	Histidine kinase
K9N54_11090	COG1335	isochorismatase
K9N54_11095	COG0577	efflux transmembrane transporter activity
K9N54_11095	COG1136	(ABC) transporter
K9N54_11105	COG0577	efflux transmembrane transporter activity
K9N54_11105	COG1136	(ABC) transporter
K9N54_11115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9N54_11145	COG3118	belongs to the thioredoxin family
K9N54_11150	COG4232	protein-disulfide reductase activity
K9N54_11190	COG2863	cytochrome
K9N54_11195	COG3258	Cytochrome c
K9N54_11200	COG2995	paraquat-inducible protein a
K9N54_11205	COG3008	intermembrane lipid transfer
K9N54_11205	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K9N54_11215	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
K9N54_11240	COG4166	transmembrane transport
K9N54_11245	COG0284	orotidine-5'-phosphate decarboxylase activity
K9N54_11250	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
K9N54_11255	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
K9N54_11265	COG0539	negative regulation of cytoplasmic translation
K9N54_11270	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K9N54_11275	COG0616	signal peptide processing
K9N54_11280	COG1028	Short-chain dehydrogenase reductase Sdr
K9N54_11295	COG0587	DNA-directed DNA polymerase activity
K9N54_11300	COG0784	Response regulator, receiver
K9N54_11300	COG0835	chemotaxis
K9N54_11305	COG1940	carbohydrate kinase activity
K9N54_11310	COG0469	pyruvate kinase activity
K9N54_11315	COG4667	esterase of the alpha-beta hydrolase superfamily
K9N54_11330	COG0733	neurotransmitter:sodium symporter activity
K9N54_11345	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K9N54_11345	COG1263	PTS System
K9N54_11350	COG0084	hydrolase, TatD family'
K9N54_11360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K9N54_11365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K9N54_11395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K9N54_11400	COG0416	fatty acid biosynthetic process
K9N54_11410	COG1399	metal-binding, possibly nucleic acid-binding protein
K9N54_11415	COG0424	maF-like protein
K9N54_11420	COG0564	pseudouridine synthase activity
K9N54_11425	COG1530	ribonuclease E activity
K9N54_11430	COG0659	secondary active sulfate transmembrane transporter activity
K9N54_11435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K9N54_11440	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
K9N54_11450	COG0572	uridine kinase
K9N54_11455	COG0489	protein tyrosine kinase activity
K9N54_11460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9N54_11460	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9N54_11470	COG2186	Transcriptional regulator
K9N54_11475	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K9N54_11480	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
K9N54_11485	COG3318	Belongs to the UPF0149 family
K9N54_11485	COG3012	SEC-C Motif Domain Protein
K9N54_11490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K9N54_11500	COG0366	Alpha amylase catalytic
K9N54_11505	COG1122	ATPase activity
K9N54_11510	COG4120	Belongs to the binding-protein-dependent transport system permease family
K9N54_11520	COG3092	negative regulation of chromosome organization
K9N54_11525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K9N54_11530	COG0280	phosphate acetyltransferase
K9N54_11530	COG0857	belongs to the CobB CobQ family
K9N54_11535	COG3174	membrane
K9N54_11545	COG0435	Glutathione S-transferase
K9N54_11555	COG0444	Belongs to the ABC transporter superfamily
K9N54_11560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K9N54_11565	COG0601	transmembrane transport
K9N54_11575	COG0314	molybdopterin synthase activity
K9N54_11580	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
K9N54_11585	COG0315	cyclic pyranopterin monophosphate synthase activity
K9N54_11590	COG0521	Mo-molybdopterin cofactor biosynthetic process
K9N54_11595	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K9N54_11600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
K9N54_11605	COG2198	Histidine kinase
K9N54_11610	COG2204	response regulator
K9N54_11615	COG0556	nucleotide-excision repair
K9N54_11625	COG4657	Part of a membrane complex involved in electron transport
K9N54_11630	COG2878	Part of a membrane complex involved in electron transport
K9N54_11635	COG4656	Part of a membrane complex involved in electron transport
K9N54_11640	COG4658	electron transport chain
K9N54_11645	COG4659	FMN binding
K9N54_11650	COG4660	Part of a membrane complex involved in electron transport
K9N54_11655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K9N54_11660	COG0346	lactoylglutathione lyase activity
K9N54_11670	COG2885	chlorophyll binding
K9N54_11675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K9N54_11680	COG2056	Na+-H+ antiporter family
K9N54_11690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
K9N54_11710	COG1454	alcohol dehydrogenase
K9N54_11710	COG1012	belongs to the aldehyde dehydrogenase family
K9N54_11715	COG2095	MarC family integral membrane protein
K9N54_11720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9N54_11725	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K9N54_11730	COG1757	Na H antiporter
K9N54_11745	COG3081	Nucleoid-associated protein
K9N54_11750	COG3082	Protein of unknown function (DUF1414)
K9N54_11755	COG3083	sulfuric ester hydrolase activity
K9N54_11765	COG0123	including yeast histone deacetylase and acetoin utilization protein
K9N54_11780	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K9N54_11785	COG0778	Nitroreductase
K9N54_11790	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9N54_11790	COG1902	pentaerythritol trinitrate reductase activity
K9N54_11795	COG0616	signal peptide processing
K9N54_11800	COG0252	asparaginase activity
K9N54_11805	COG3139	Protein of unknown function (DUF1315)
K9N54_11815	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9N54_11820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K9N54_11835	COG2226	methyltransferase
K9N54_11850	COG1785	Belongs to the alkaline phosphatase family
K9N54_11860	COG0346	lactoylglutathione lyase activity
K9N54_11865	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
K9N54_11870	COG0668	transmembrane transport
K9N54_11875	COG2983	Belongs to the UPF0260 family
K9N54_11880	COG2261	transglycosylase associated protein
K9N54_11895	COG3681	Belongs to the UPF0597 family
K9N54_11900	COG0251	oxidation-reduction process
K9N54_11905	COG0814	amino acid
K9N54_11910	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K9N54_11915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K9N54_11920	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K9N54_11930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
K9N54_11935	COG2832	Protein of unknown function (DUF454)
K9N54_11940	COG0745	RESPONSE REGULATOR receiver
K9N54_11945	COG0583	DNA-binding transcription factor activity
K9N54_11950	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K9N54_11955	COG1286	toxin biosynthetic process
K9N54_11960	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
K9N54_11965	COG0285	dihydrofolate synthase activity
K9N54_11970	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K9N54_11975	COG0101	tRNA pseudouridine synthase activity
K9N54_11985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K9N54_11990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9N54_11995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K9N54_12000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9N54_12000	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
K9N54_12005	COG0431	NADPH-dependent FMN reductase
K9N54_12015	COG3101	peptidyl-lysine hydroxylation
K9N54_12020	COG2860	membrane
K9N54_12025	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K9N54_12030	COG2890	protein-(glutamine-N5) methyltransferase activity
K9N54_12035	COG2840	Smr protein MutS2
K9N54_12040	COG2062	phosphohistidine phosphatase, SixA
K9N54_12055	COG1024	Enoyl-CoA hydratase
K9N54_12055	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9N54_12060	COG0183	Belongs to the thiolase family
K9N54_12075	COG2067	long-chain fatty acid transport protein
K9N54_12080	COG2067	long-chain fatty acid transport protein
K9N54_12085	COG2853	Lipoprotein
K9N54_12100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9N54_12105	COG1138	Cytochrome C-type biogenesis protein
K9N54_12110	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
K9N54_12115	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K9N54_12120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K9N54_12125	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K9N54_12130	COG4133	protoheme IX ABC transporter activity
K9N54_12140	COG0835	chemotaxis
K9N54_12150	COG1192	Involved in chromosome partitioning
K9N54_12155	COG2201	protein-glutamate methylesterase activity
K9N54_12160	COG2198	Histidine kinase
K9N54_12160	COG0643	Histidine kinase
K9N54_12160	COG0784	Response regulator, receiver
K9N54_12165	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
K9N54_12205	COG1987	bacterial-type flagellum assembly
K9N54_12255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K9N54_12265	COG1677	Flagellar hook-basal body complex protein FliE
K9N54_12285	COG1516	flagellar protein fliS
K9N54_12295	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K9N54_12300	COG1334	flagellar protein FlaG
K9N54_12305	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K9N54_12310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K9N54_12315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K9N54_12320	COG2837	iron assimilation
K9N54_12345	COG1393	Belongs to the ArsC family
K9N54_12350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9N54_12365	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
K9N54_12370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9N54_12375	COG2716	regulation of RNA biosynthetic process
K9N54_12405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K9N54_12455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K9N54_12470	COG4783	chaperone-mediated protein folding
K9N54_12475	COG1393	Belongs to the ArsC family
K9N54_12495	COG2233	PERMEase
K9N54_12500	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K9N54_12505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K9N54_12510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K9N54_12515	COG0121	glutamine amidotransferase
K9N54_12520	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
K9N54_12525	COG1960	acyl-CoA dehydrogenase activity
K9N54_12540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K9N54_12545	COG0328	RNA-DNA hybrid ribonuclease activity
K9N54_12550	COG2226	methyltransferase
K9N54_12555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9N54_12560	COG0741	lytic transglycosylase activity
K9N54_12560	COG1388	LysM domain
K9N54_12570	COG3021	interspecies interaction between organisms
K9N54_12575	COG0347	Belongs to the P(II) protein family
K9N54_12585	COG0037	tRNA processing
K9N54_12590	COG0825	malonyl-CoA metabolic process
K9N54_12595	COG0587	DNA-directed DNA polymerase activity
K9N54_12600	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K9N54_12605	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9N54_12610	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9N54_12615	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K9N54_12620	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9N54_12625	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
K9N54_12635	COG0750	zinc metalloprotease
K9N54_12640	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
K9N54_12645	COG0575	Belongs to the CDS family
K9N54_12650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K9N54_12655	COG0233	cytoplasmic translational termination
K9N54_12660	COG0528	UMP kinase activity
K9N54_12665	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K9N54_12670	COG0052	Belongs to the universal ribosomal protein uS2 family
K9N54_12675	COG0024	Methionine aminopeptidase
K9N54_12680	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K9N54_12690	COG0564	pseudouridine synthase activity
K9N54_12695	COG3098	single-species biofilm formation
K9N54_12720	COG1671	Belongs to the UPF0178 family
K9N54_12725	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
K9N54_12735	COG0254	rRNA binding
K9N54_12740	COG1720	tRNA m6t6A37 methyltransferase activity
K9N54_12745	COG0442	prolyl-tRNA aminoacylation
K9N54_12765	COG0733	neurotransmitter:sodium symporter activity
K9N54_12780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9N54_12785	COG0514	ATP-dependent DNA helicase (RecQ)
K9N54_12790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K9N54_12805	COG1477	protein flavinylation
K9N54_12810	COG2871	sodium ion transport
K9N54_12815	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K9N54_12820	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K9N54_12825	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K9N54_12830	COG1805	sodium ion transport
K9N54_12835	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
K9N54_12840	COG0271	Belongs to the BolA IbaG family
K9N54_12845	COG2813	Specifically methylates the guanine in position
K9N54_12850	COG3056	Lipoprotein
K9N54_12870	COG1595	DNA-templated transcription, initiation
K9N54_12895	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K9N54_12900	COG0693	protein deglycase activity
K9N54_12905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K9N54_12910	COG3706	GGDEF domain
K9N54_12915	COG2166	iron-sulfur cluster assembly
K9N54_12920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K9N54_12925	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
K9N54_12935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K9N54_12935	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K9N54_12945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9N54_12950	COG1074	ATP-dependent DNA helicase activity
K9N54_12955	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
K9N54_12975	COG3141	response to X-ray
K9N54_12980	COG2171	N-acyltransferase activity
K9N54_12985	COG0584	glycerophosphoryl diester phosphodiesterase
K9N54_12990	COG2271	Major facilitator Superfamily
K9N54_12995	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
K9N54_13000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K9N54_13005	COG1349	DNA-binding transcription factor activity
K9N54_13010	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K9N54_13015	COG0598	Magnesium transport protein CorA
K9N54_13030	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9N54_13035	COG1609	Transcriptional regulator
K9N54_13040	COG2211	Major facilitator Superfamily
K9N54_13055	COG2017	converts alpha-aldose to the beta-anomer
K9N54_13060	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
K9N54_13070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K9N54_13075	COG1609	Transcriptional regulator
K9N54_13080	COG3250	beta-galactosidase activity
K9N54_13085	COG2731	YhcH YjgK YiaL family protein
K9N54_13090	COG0531	amino acid
K9N54_13095	COG0583	DNA-binding transcription factor activity
K9N54_13155	COG4964	Belongs to the GSP D family
K9N54_13180	COG2169	Transcriptional regulator
K9N54_13185	COG1022	Amp-dependent synthetase and ligase
K9N54_13195	COG0583	DNA-binding transcription factor activity
K9N54_13200	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K9N54_13205	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K9N54_13215	COG0560	Phosphoserine phosphatase
K9N54_13225	COG0813	purine-nucleoside phosphorylase activity
K9N54_13230	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
K9N54_13235	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
K9N54_13240	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
K9N54_13245	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K9N54_13250	COG0084	hydrolase, TatD family'
K9N54_13260	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
K9N54_13280	COG3153	acetyltransferase
K9N54_13285	COG3154	lipid carrier protein
K9N54_13295	COG0826	peptidase U32
K9N54_13300	COG0826	peptidase U32
K9N54_13305	COG0534	Mate efflux family protein
K9N54_13320	COG1185	polyribonucleotide nucleotidyltransferase activity
K9N54_13325	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K9N54_13330	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K9N54_13335	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K9N54_13340	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K9N54_13345	COG0195	Participates in both transcription termination and antitermination
K9N54_13350	COG0779	Required for maturation of 30S ribosomal subunits
K9N54_13365	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K9N54_13370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9N54_13375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K9N54_13380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K9N54_13385	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
K9N54_13390	COG1534	Rna-binding protein
K9N54_13395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9N54_13400	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K9N54_13405	COG2027	D-alanyl-D-alanine carboxypeptidase
K9N54_13415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K9N54_13420	COG0739	heme binding
K9N54_13435	COG0316	Belongs to the HesB IscA family
K9N54_13440	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K9N54_13445	COG0628	permease
K9N54_13450	COG2813	Specifically methylates the guanine in position
K9N54_13455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9N54_13455	COG0784	Response regulator, receiver
K9N54_13455	COG2205	protein histidine kinase activity
K9N54_13455	COG2198	Histidine kinase
K9N54_13460	COG0747	negative chemotaxis
K9N54_13470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K9N54_13475	COG0444	Belongs to the ABC transporter superfamily
K9N54_13480	COG4608	Belongs to the ABC transporter superfamily
K9N54_13490	COG2971	BadF BadG BcrA BcrD
K9N54_13505	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9N54_13510	COG3842	ATPase activity
K9N54_13520	COG1840	ABC-type Fe3 transport system, periplasmic component
K9N54_13525	COG0004	ammonium transporteR
K9N54_13535	COG3112	Uncharacterised protein family (UPF0231)
K9N54_13540	COG1049	propionate catabolic process, 2-methylcitrate cycle
K9N54_13545	COG1752	Esterase of the alpha-beta hydrolase superfamily
K9N54_13550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K9N54_13555	COG1643	Atp-dependent helicase
K9N54_13560	COG1489	DNA binding
K9N54_13570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9N54_13580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K9N54_13585	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K9N54_13590	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K9N54_13595	COG1560	Kdo2-lipid A biosynthetic process
K9N54_13600	COG0842	Transport permease protein
K9N54_13605	COG1131	(ABC) transporter
K9N54_13610	COG0659	secondary active sulfate transmembrane transporter activity
K9N54_13615	COG0288	reversible hydration of carbon dioxide
K9N54_13630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9N54_13635	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9N54_13640	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
K9N54_13645	COG2186	Transcriptional regulator
K9N54_13655	COG0157	Belongs to the NadC ModD family
K9N54_13665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K9N54_13670	COG1459	type II secretion system
K9N54_13680	COG0237	dephospho-CoA kinase activity
K9N54_13685	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
K9N54_13690	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
K9N54_13695	COG0335	large ribosomal subunit rRNA binding
K9N54_13700	COG0336	Belongs to the RNA methyltransferase TrmD family
K9N54_13705	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K9N54_13710	COG0228	four-way junction DNA binding
K9N54_13715	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K9N54_13720	COG4137	Cytochrome C assembly protein
K9N54_13725	COG4536	flavin adenine dinucleotide binding
K9N54_13730	COG1854	S-ribosylhomocysteine lyase activity
K9N54_13740	COG2918	glutathione biosynthetic process
K9N54_13745	COG0612	Peptidase, M16
K9N54_13750	COG1238	metal cluster binding
K9N54_13760	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
K9N54_13765	COG0511	ligase activity, forming carbon-carbon bonds
K9N54_13765	COG5016	pyruvate
K9N54_13770	COG3630	sodium ion export across plasma membrane
K9N54_13825	COG0527	aspartate kinase activity
K9N54_13830	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K9N54_13835	COG2137	regulation of response to DNA damage stimulus
K9N54_13840	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K9N54_13845	COG1546	Belongs to the CinA family
K9N54_13850	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K9N54_13855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K9N54_13865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K9N54_13870	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
K9N54_13875	COG0585	pseudouridine synthase activity
K9N54_13880	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K9N54_13885	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K9N54_13890	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
K9N54_13895	COG0148	phosphopyruvate hydratase activity
K9N54_13900	COG0504	CTP synthase activity
K9N54_13905	COG3956	TIGRFAM MazG family protein
K9N54_13910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K9N54_13915	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K9N54_13925	COG0736	holo-[acyl-carrier-protein] synthase activity
K9N54_13930	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K9N54_13935	COG1381	Involved in DNA repair and RecF pathway recombination
K9N54_13940	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K9N54_13945	COG0571	ribonuclease III activity
K9N54_13955	COG0481	GTPase activity
K9N54_13960	COG3086	response to oxidative stress
K9N54_13970	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
K9N54_13975	COG1595	DNA-templated transcription, initiation
K9N54_13980	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K9N54_13990	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
K9N54_13995	COG0354	folic acid binding
K9N54_14010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9N54_14015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9N54_14020	COG3079	Belongs to the UPF0149 family
K9N54_14025	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
K9N54_14035	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K9N54_14040	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K9N54_14045	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9N54_14055	COG0583	DNA-binding transcription factor activity
K9N54_14065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K9N54_14070	COG0668	transmembrane transport
K9N54_14075	COG0191	fructose-bisphosphate aldolase activity
K9N54_14080	COG0126	phosphoglycerate kinase activity
K9N54_14085	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K9N54_14090	COG4771	TonB-dependent receptor
K9N54_14095	COG0583	DNA-binding transcription factor activity
K9N54_14100	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K9N54_14105	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K9N54_14115	COG3091	SprT-like family
K9N54_14120	COG2356	endonuclease I
K9N54_14125	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K9N54_14130	COG0189	ligase activity
K9N54_14135	COG1678	Uncharacterized ACR, COG1678
K9N54_14140	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K9N54_14155	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
K9N54_14160	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
K9N54_14165	COG0762	integral membrane protein
K9N54_14170	COG1872	DUF167
K9N54_14180	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K9N54_14185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K9N54_14190	COG2066	Belongs to the glutaminase family
K9N54_14200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K9N54_14210	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
K9N54_14215	COG0741	lytic transglycosylase activity
K9N54_14255	COG0840	transmembrane signaling receptor activity
K9N54_14285	COG1012	belongs to the aldehyde dehydrogenase family
K9N54_14330	COG3437	response regulator, receiver
K9N54_14340	COG3394	polysaccharide catabolic process
K9N54_14345	COG1486	melibiose metabolic process
K9N54_14350	COG1447	Phosphotransferase system cellobiose-specific component IIA
K9N54_14355	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K9N54_14360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
K9N54_14365	COG0726	polysaccharide deacetylase
K9N54_14405	COG0582	viral genome integration into host DNA
K9N54_14535	COG1028	Short-chain dehydrogenase reductase Sdr
K9N54_14550	COG0795	lipopolysaccharide-transporting ATPase activity
K9N54_14555	COG0795	lipopolysaccharide-transporting ATPase activity
K9N54_14560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K9N54_14565	COG2927	DNA polymerase III (CHI subunit)
K9N54_14570	COG0525	valine-tRNA ligase activity
K9N54_14625	COG3501	Rhs element vgr protein
K9N54_14710	COG2235	arginine
K9N54_14715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K9N54_14725	COG0540	Belongs to the ATCase OTCase family
K9N54_14730	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
K9N54_14735	COG0251	oxidation-reduction process
K9N54_14740	COG0204	Acyl-transferase
K9N54_14745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K9N54_14750	COG5007	Belongs to the BolA IbaG family
K9N54_14760	COG2854	intermembrane phospholipid transfer
K9N54_14765	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K9N54_14770	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K9N54_14775	COG1127	ABC transporter
K9N54_14785	COG0517	IMP dehydrogenase activity
K9N54_14785	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K9N54_14795	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
K9N54_14800	COG1137	ATPase activity
K9N54_14810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K9N54_14815	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9N54_14820	COG1660	Displays ATPase and GTPase activities
K9N54_14825	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9N54_14830	COG2239	Acts as a magnesium transporter
K9N54_14835	COG0312	modulator of DNA gyrase
K9N54_14840	COG3028	Belongs to the UPF0307 family
K9N54_14845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K9N54_14850	COG0564	pseudouridine synthase activity
K9N54_14860	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
K9N54_14865	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
K9N54_14870	COG0312	modulator of DNA gyrase
K9N54_14875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9N54_14880	COG3164	Protein of unknown function
K9N54_14890	COG0424	maF-like protein
K9N54_14895	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
K9N54_14900	COG1792	Involved in formation and maintenance of cell shape
K9N54_14905	COG1077	Cell shape determining protein MreB Mrl
K9N54_14940	COG2165	general secretion pathway protein
K9N54_14950	COG1459	type II secretion system
K9N54_14955	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K9N54_14965	COG3267	Type II secretory pathway component ExeA
K9N54_14965	COG3409	Peptidoglycan-binding domain 1 protein
K9N54_14990	COG2199	diguanylate cyclase activity
K9N54_14990	COG2200	EAL domain
K9N54_14995	COG0629	single-stranded DNA binding
K9N54_15010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K9N54_15020	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K9N54_15025	COG0527	aspartate kinase activity
K9N54_15030	COG0646	methionine synthase
K9N54_15030	COG1410	methionine synthase
K9N54_15045	COG3335	DDE superfamily endonuclease
K9N54_15100	COG0175	sulfate reduction
K9N54_15105	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9N54_15110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K9N54_15130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K9N54_15135	COG0735	belongs to the Fur family
K9N54_15145	COG0166	Belongs to the GPI family
K9N54_15150	COG0432	Pfam Uncharacterised protein family UPF0047
K9N54_15160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K9N54_15175	COG0359	binds to the 23S rRNA
K9N54_15185	COG2965	DNA replication, synthesis of RNA primer
K9N54_15190	COG0360	Binds together with S18 to 16S ribosomal RNA
K9N54_15195	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K9N54_15200	COG0338	D12 class N6 adenine-specific DNA methyltransferase
K9N54_15210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K9N54_15215	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K9N54_15245	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K9N54_15255	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K9N54_15255	COG0678	peroxiredoxin activity
K9N54_15265	COG0165	Argininosuccinate lyase
K9N54_15265	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
K9N54_15270	COG0137	argininosuccinate synthase activity
K9N54_15275	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K9N54_15280	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K9N54_15285	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9N54_15290	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
K9N54_15300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K9N54_15305	COG0460	homoserine dehydrogenase
K9N54_15305	COG0527	aspartate kinase activity
K9N54_15310	COG0626	cystathionine gamma-synthase activity
K9N54_15320	COG0281	malic enzyme
K9N54_15330	COG2906	2 iron, 2 sulfur cluster binding
K9N54_15335	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K9N54_15340	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K9N54_15345	COG0049	tRNA binding
K9N54_15355	COG2168	tRNA wobble position uridine thiolation
K9N54_15360	COG2923	Belongs to the DsrF TusC family
K9N54_15365	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
K9N54_15370	COG2964	Protein conserved in bacteria
K9N54_15375	COG0545	Peptidyl-prolyl cis-trans isomerase
K9N54_15385	COG2900	Belongs to the SlyX family
K9N54_15390	COG1446	asparaginase
K9N54_15395	COG1047	Peptidyl-prolyl cis-trans
K9N54_15410	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9N54_15415	COG0488	(ABC) transporter
K9N54_15425	COG0429	hydrolase of the alpha beta-hydrolase fold
K9N54_15430	COG3089	Belongs to the UPF0270 family
K9N54_15435	COG3954	Phosphoribulokinase
K9N54_15440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9N54_15450	COG1012	belongs to the aldehyde dehydrogenase family
K9N54_15460	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K9N54_15465	COG0512	Glutamine amidotransferase of anthranilate synthase
K9N54_15480	COG0180	Tryptophanyl-tRNA synthetase
K9N54_15485	COG0546	phosphoglycolate phosphatase activity
K9N54_15490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9N54_15495	COG0557	exoribonuclease II activity
K9N54_15500	COG1959	2 iron, 2 sulfur cluster binding
K9N54_15505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9N54_15505	COG1017	nitric oxide dioxygenase activity
K9N54_15510	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
K9N54_15515	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K9N54_15520	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
K9N54_15525	COG0330	HflC and HflK could
K9N54_15530	COG0330	HflC and HflK could
K9N54_15535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K9N54_15545	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K9N54_15550	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K9N54_15555	COG0860	N-Acetylmuramoyl-L-alanine amidase
K9N54_15560	COG0802	atpase or kinase
K9N54_15565	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K9N54_15635	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
K9N54_15640	COG1162	GTPase activity
K9N54_15645	COG0688	phosphatidylethanolamine metabolic process
K9N54_15650	COG0471	metal ion transport
K9N54_15695	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K9N54_15700	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K9N54_15705	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
K9N54_15710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K9N54_15715	COG1045	serine acetyltransferase
K9N54_15720	COG4942	peptidase
K9N54_15740	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
K9N54_15745	COG1053	succinate dehydrogenase
K9N54_15750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K9N54_15755	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
K9N54_15760	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
K9N54_15770	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K9N54_15775	COG1509	lysine 2,3-aminomutase activity
K9N54_15780	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K9N54_15795	COG0459	protein refolding
K9N54_15805	COG0534	Mate efflux family protein
K9N54_15810	COG0205	6-phosphofructokinase activity
K9N54_15820	COG3678	ATP-independent chaperone mediated protein folding
K9N54_15825	COG0745	RESPONSE REGULATOR receiver
K9N54_15830	COG2205	protein histidine kinase activity
K9N54_15840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K9N54_15845	COG3030	protein affecting phage T7 exclusion by the F plasmid
K9N54_15850	COG1027	Aspartate ammonia-lyase
K9N54_15855	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K9N54_15860	COG4232	protein-disulfide reductase activity
K9N54_15870	COG3263	regulation of cellular component size
K9N54_15880	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9N54_15900	COG2205	protein histidine kinase activity
K9N54_15900	COG2198	Histidine kinase
K9N54_15900	COG0784	Response regulator, receiver
K9N54_15905	COG2814	Major facilitator Superfamily
K9N54_15920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9N54_15925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K9N54_15930	COG0511	ligase activity, forming carbon-carbon bonds
K9N54_15935	COG0439	Biotin carboxylase
K9N54_15940	COG2264	protein methyltransferase activity
K9N54_15945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K9N54_15950	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
K9N54_15955	COG2814	Major facilitator Superfamily
K9N54_15960	COG0488	(ABC) transporter
K9N54_15965	COG3706	GGDEF domain
K9N54_16035	COG1982	Orn Lys Arg decarboxylase major
K9N54_16040	COG0531	amino acid
K9N54_16045	COG3710	Transcriptional regulator
K9N54_16050	COG0789	Transcriptional regulator
K9N54_16055	COG0138	bifunctional purine biosynthesis protein purh
K9N54_16060	COG0151	Belongs to the GarS family
K9N54_16075	COG1253	flavin adenine dinucleotide binding
K9N54_16085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9N54_16090	COG1573	uracil-dna glycosylase
K9N54_16095	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K9N54_16110	COG2816	NAD+ diphosphatase activity
K9N54_16115	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
K9N54_16120	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K9N54_16125	COG0085	RNA polymerase activity
K9N54_16130	COG0222	ribosome binding
K9N54_16135	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K9N54_16140	COG0081	regulation of translation
K9N54_16145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K9N54_16150	COG0250	Participates in transcription elongation, termination and antitermination
K9N54_16155	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K9N54_16160	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K9N54_16195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K9N54_16205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9N54_16260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K9N54_16270	COG4206	TonB-dependent receptor
K9N54_16275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K9N54_16290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9N54_16295	COG0534	Mate efflux family protein
K9N54_16300	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K9N54_16305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K9N54_16310	COG2937	Belongs to the GPAT DAPAT family
K9N54_16315	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K9N54_16320	COG3161	chorismate lyase activity
K9N54_16325	COG1580	Controls the rotational direction of flagella during chemotaxis
K9N54_16330	COG0705	Rhomboid family
K9N54_16335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K9N54_16345	COG2177	Part of the ABC transporter FtsEX involved in
K9N54_16350	COG2884	Cell division ATP-binding protein ftsE
K9N54_16355	COG0552	protein localization to endoplasmic reticulum
K9N54_16360	COG0742	ribosomal rna small subunit methyltransferase
K9N54_16370	COG2095	MarC family integral membrane protein
K9N54_16420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K9N54_16425	COG0640	Transcriptional regulator
K9N54_16430	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
K9N54_16435	COG1280	lysine exporter protein (LysE YggA)
K9N54_16440	COG2267	carboxylic ester hydrolase activity
K9N54_16445	COG0561	phosphatase activity
K9N54_16460	COG3148	PFAM DTW domain containing protein
K9N54_16465	COG2200	EAL domain
K9N54_16465	COG3287	FIST C domain
K9N54_16465	COG2199	diguanylate cyclase activity
K9N54_16470	COG1011	Hydrolase
K9N54_16475	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
K9N54_16485	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K9N54_16490	COG0019	diaminopimelate decarboxylase activity
K9N54_16500	COG1965	Belongs to the frataxin family
K9N54_16505	COG3072	Adenylate cyclase
K9N54_16510	COG0181	hydroxymethylbilane synthase activity
K9N54_16515	COG1587	Uroporphyrinogen-III synthase
K9N54_16520	COG2959	enzyme of heme biosynthesis
K9N54_16525	COG3071	HemY protein
K9N54_16570	COG0633	Ferredoxin
K9N54_16575	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
K9N54_16590	COG3118	belongs to the thioredoxin family
K9N54_16595	COG0513	Belongs to the DEAD box helicase family
K9N54_16600	COG0248	Ppx GppA phosphatase
K9N54_16605	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
K9N54_16615	COG0514	ATP-dependent DNA helicase (RecQ)
K9N54_16620	COG2962	Rard protein
K9N54_16630	COG1280	lysine exporter protein (LysE YggA)
K9N54_16645	COG0210	DNA helicase
K9N54_16655	COG3220	belongs to the UPF0276 family
K9N54_16685	COG0006	proline dipeptidase activity
K9N54_16695	COG2022	thiamine diphosphate biosynthetic process
K9N54_16700	COG2104	thiamine diphosphate biosynthetic process
K9N54_16705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K9N54_16710	COG0352	thiamine-phosphate diphosphorylase activity
K9N54_16715	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
K9N54_16720	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K9N54_16780	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
K9N54_16835	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
K9N54_16890	COG0582	viral genome integration into host DNA
K9N54_16930	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K9N54_16940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K9N54_16945	COG0408	coproporphyrinogen oxidase activity
K9N54_16950	COG0009	L-threonylcarbamoyladenylate synthase
K9N54_16955	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
K9N54_16960	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K9N54_16965	COG0551	DNA topoisomerase type I activity
K9N54_16970	COG2922	Belongs to the Smg family
K9N54_16975	COG0758	DNA mediated transformation
K9N54_16985	COG0242	peptide deformylase activity
K9N54_16990	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K9N54_16995	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K9N54_16995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K9N54_17000	COG0569	domain protein
K9N54_17005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K9N54_17015	COG1272	protein, Hemolysin III
K9N54_17020	COG4326	sporulation control protein
K9N54_17030	COG3084	Protein conserved in bacteria
K9N54_17040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K9N54_17045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9N54_17050	COG0204	Acyl-transferase
K9N54_17060	COG0606	chelatase, subunit chli
K9N54_17070	COG3978	acetolactate synthase activity
K9N54_17075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K9N54_17080	COG0129	dihydroxy-acid dehydratase activity
K9N54_17090	COG0583	DNA-binding transcription factor activity
K9N54_17095	COG2814	Major facilitator Superfamily
K9N54_17100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9N54_17105	COG0765	amino acid transport
K9N54_17110	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K9N54_17115	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K9N54_17120	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K9N54_17125	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K9N54_17130	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K9N54_17135	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K9N54_17150	COG0356	it plays a direct role in the translocation of protons across the membrane
K9N54_17155	COG3312	ion transport
K9N54_17160	COG1475	DNA binding
K9N54_17165	COG1192	Involved in chromosome partitioning
K9N54_17170	COG0357	Ribosomal RNA small subunit methyltransferase G
K9N54_17175	COG0445	tRNA wobble uridine modification
K9N54_17180	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K9N54_17185	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K9N54_17190	COG0706	membrane insertase activity
K9N54_17200	COG0594	ribonuclease P activity
K9N54_17210	COG1126	abc transporter atp-binding protein
K9N54_17225	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K9N54_17230	COG0592	DNA-directed DNA polymerase activity
K9N54_17235	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K9N54_17240	COG0187	DNA topoisomerase II activity
K9N54_17250	COG0071	Belongs to the small heat shock protein (HSP20) family
K9N54_17275	COG0242	peptide deformylase activity
K9N54_17320	COG2176	DNA-directed DNA polymerase activity
K9N54_17325	COG0583	DNA-binding transcription factor activity
K9N54_17330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K9N54_17380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K9N54_17380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K9N54_17385	COG0509	glycine decarboxylation via glycine cleavage system
K9N54_17390	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K9N54_17430	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
K9N54_17430	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9N54_17430	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9N54_17435	COG1105	Belongs to the carbohydrate kinase PfkB family
K9N54_17440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9N54_17440	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9N54_17445	COG1609	Transcriptional regulator
K9N54_17460	COG2199	diguanylate cyclase activity
K9N54_17460	COG2200	EAL domain
K9N54_17460	COG2203	Gaf domain
K9N54_17465	COG0765	amino acid transport
K9N54_17470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9N54_17475	COG0765	amino acid transport
K9N54_17480	COG1126	abc transporter atp-binding protein
K9N54_17485	COG0469	pyruvate kinase activity
K9N54_17490	COG2271	Major facilitator Superfamily
K9N54_17515	COG1979	alcohol dehydrogenase
K9N54_17520	COG2207	Transcriptional regulator
K9N54_17530	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
K9N54_17535	COG2759	Belongs to the formate--tetrahydrofolate ligase family
K9N54_17540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K9N54_17555	COG3437	response regulator, receiver
K9N54_17555	COG0784	Response regulator, receiver
K9N54_17560	COG0546	phosphoglycolate phosphatase activity
K9N54_17565	COG0840	transmembrane signaling receptor activity
K9N54_17570	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
K9N54_17575	COG0513	Belongs to the DEAD box helicase family
K9N54_17580	COG4943	cyclic-guanylate-specific phosphodiesterase activity
K9N54_17595	COG3038	cytochrome b561
K9N54_17600	COG2353	YceI-like domain
K9N54_17605	COG2116	formate transmembrane transporter activity
K9N54_17610	COG0583	DNA-binding transcription factor activity
K9N54_17620	COG3593	DNA synthesis involved in DNA repair
K9N54_17625	COG0737	Belongs to the 5'-nucleotidase family
K9N54_17630	COG0861	Integral membrane protein TerC family
K9N54_17645	COG2267	carboxylic ester hydrolase activity
K9N54_17650	COG2067	long-chain fatty acid transport protein
K9N54_17665	COG2050	protein possibly involved in aromatic compounds catabolism
K9N54_17675	COG4533	DNA binding
K9N54_17700	COG0484	heat shock protein binding
K9N54_17710	COG3300	MHYT domain
K9N54_17710	COG5001	Diguanylate cyclase
K9N54_17715	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K9N54_17725	COG4181	ATPase activity
K9N54_17730	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
K9N54_17740	COG1984	allophanate hydrolase subunit 2
K9N54_17745	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K9N54_17750	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K9N54_17755	COG5001	Diguanylate cyclase
K9N54_17755	COG5002	protein histidine kinase activity
K9N54_17755	COG3447	MASE1 domain protein
K9N54_17760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K9N54_17770	COG0583	DNA-binding transcription factor activity
K9N54_17775	COG0045	succinate-CoA ligase (ADP-forming) activity
K9N54_17775	COG1042	CoA-binding domain protein
K9N54_17775	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K9N54_17785	COG1181	Belongs to the D-alanine--D-alanine ligase family
K9N54_17795	COG0023	Translation Initiation Factor
K9N54_17845	COG4128	Pfam Zonular occludens toxin
K9N54_18015	COG0583	DNA-binding transcription factor activity
K9N54_18025	COG0589	response to stress
K9N54_18030	COG3140	Belongs to the UPF0181 family
K9N54_18055	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
K9N54_18060	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
K9N54_18085	COG4251	negative regulation of phosphorylation
K9N54_18085	COG3706	GGDEF domain
K9N54_18085	COG2203	Gaf domain
K9N54_18085	COG5001	Diguanylate cyclase
K9N54_18095	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
K9N54_18100	COG4149	molybdate abc transporter
K9N54_18105	COG0725	ABC transporter, periplasmic molybdate-binding protein
K9N54_18110	COG1492	cobalamin metabolic process
K9N54_18115	COG3111	PFAM Bacterial OB fold (BOF) protein
K9N54_18125	COG0189	ligase activity
K9N54_18125	COG4067	protein conserved in archaea
K9N54_18140	COG0534	Mate efflux family protein
K9N54_18145	COG0602	queuosine metabolic process
K9N54_18150	COG1328	CTP reductase activity
K9N54_18165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9N54_18195	COG0243	molybdopterin cofactor binding
K9N54_18200	COG0583	DNA-binding transcription factor activity
K9N54_18205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K9N54_18215	COG2197	response regulator
K9N54_18220	COG3851	Histidine kinase
K9N54_18225	COG2271	Major facilitator Superfamily
K9N54_18250	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K9N54_18255	COG3118	belongs to the thioredoxin family
K9N54_18265	COG3292	Two component regulator propeller
K9N54_18265	COG2205	protein histidine kinase activity
K9N54_18265	COG0745	RESPONSE REGULATOR receiver
K9N54_18270	COG0534	Mate efflux family protein
K9N54_18300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
K9N54_18320	COG2116	formate transmembrane transporter activity
K9N54_18330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9N54_18335	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9N54_18370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9N54_18370	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K9N54_18410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K9N54_18425	COG0277	FAD linked oxidase domain protein
K9N54_18430	COG0583	DNA-binding transcription factor activity
K9N54_18445	COG2425	protein containing a von Willebrand factor type A (vWA) domain
K9N54_18460	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
K9N54_18470	COG1288	antiporter activity
K9N54_18480	COG2814	Major facilitator Superfamily
K9N54_18490	COG3040	lipid binding
K9N54_18510	COG0419	ATPase involved in DNA repair
K9N54_18515	COG0420	3'-5' exonuclease activity
K9N54_18585	COG0631	protein serine/threonine phosphatase activity
K9N54_18620	COG0515	serine threonine protein kinase
K9N54_18620	COG2815	serine threonine protein kinase
K9N54_18675	COG2146	nitrite reductase [NAD(P)H] activity
K9N54_18675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9N54_18680	COG1116	anion transmembrane transporter activity
K9N54_18685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9N54_18690	COG1116	anion transmembrane transporter activity
K9N54_18690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9N54_18695	COG3707	response regulator
K9N54_18715	COG0243	molybdopterin cofactor binding
K9N54_18725	COG0814	amino acid
K9N54_18750	COG1785	Belongs to the alkaline phosphatase family
K9N54_18765	COG0745	RESPONSE REGULATOR receiver
K9N54_18785	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
K9N54_18800	COG1609	Transcriptional regulator
K9N54_18805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K9N54_18810	COG1879	ABC-type sugar transport system periplasmic component
K9N54_18815	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9N54_18820	COG1129	ABC transporter
K9N54_18825	COG1869	D-ribose catabolic process
K9N54_18830	COG5001	Diguanylate cyclase
K9N54_18835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K9N54_18890	COG2205	protein histidine kinase activity
K9N54_18890	COG0784	Response regulator, receiver
K9N54_18900	COG5001	Diguanylate cyclase
K9N54_18900	COG3300	MHYT domain
K9N54_18910	COG0330	HflC and HflK could
K9N54_18925	COG0517	IMP dehydrogenase activity
K9N54_18925	COG4175	Glycine betaine
K9N54_18930	COG4176	ABC-type proline glycine betaine transport system permease component
K9N54_18945	COG1012	belongs to the aldehyde dehydrogenase family
K9N54_18950	COG1309	transcriptional regulator
K9N54_18955	COG3706	GGDEF domain
K9N54_18960	COG1028	Short-chain dehydrogenase reductase Sdr
K9N54_18975	COG1024	Enoyl-CoA hydratase
K9N54_18980	COG1960	acyl-CoA dehydrogenase activity
K9N54_18990	COG0183	Belongs to the thiolase family
K9N54_19000	COG1960	acyl-CoA dehydrogenase activity
K9N54_19005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K9N54_19010	COG1024	Enoyl-CoA hydratase
K9N54_19015	COG4770	biotin carboxylase activity
K9N54_19025	COG2205	protein histidine kinase activity
K9N54_19025	COG3437	response regulator, receiver
K9N54_19025	COG3850	Histidine kinase
K9N54_19025	COG4999	Histidine kinase
K9N54_19040	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
K9N54_19040	COG3264	Mechanosensitive ion channel
K9N54_19045	COG0110	maltose O-acetyltransferase activity
K9N54_19050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9N54_19055	COG1271	oxidase subunit
K9N54_19060	COG1294	oxidase, subunit
K9N54_19070	COG0384	phenazine biosynthesis protein PhzF
K9N54_19075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K9N54_19080	COG0789	Transcriptional regulator
K9N54_19090	COG3474	cytochrome
K9N54_19155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9N54_19160	COG0516	GMP reductase activity
K9N54_19165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K9N54_19165	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K9N54_19180	COG4989	oxidoreductase activity
K9N54_19195	COG0038	chloride channel
K9N54_19205	COG1914	H( )-stimulated, divalent metal cation uptake system
K9N54_19210	COG0302	gtp cyclohydrolase
K9N54_19220	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K9N54_19240	COG2897	thiosulfate sulfurtransferase activity
K9N54_19260	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K9N54_19265	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K9N54_19270	COG0840	transmembrane signaling receptor activity
K9N54_19275	COG2814	Major facilitator Superfamily
K9N54_19280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K9N54_19290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9N54_19300	COG0840	transmembrane signaling receptor activity
K9N54_19320	COG2195	Cleaves the N-terminal amino acid of tripeptides
K9N54_19335	COG2197	response regulator
K9N54_19340	COG3850	Histidine kinase
K9N54_19345	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K9N54_19355	COG0243	molybdopterin cofactor binding
K9N54_19365	COG3005	denitrification pathway
K9N54_19385	COG0183	Belongs to the thiolase family
K9N54_19405	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K9N54_19410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K9N54_19435	COG1522	sequence-specific DNA binding
K9N54_19455	COG1566	PFAM secretion protein HlyD family protein
K9N54_19465	COG0784	Response regulator, receiver
K9N54_19465	COG2205	protein histidine kinase activity
K9N54_19470	COG1879	ABC-type sugar transport system periplasmic component
K9N54_19475	COG2827	Endonuclease containing a URI domain
K9N54_19480	COG3132	Protein of unknown function, DUF480
K9N54_19495	COG2926	Belongs to the UPF0265 family
K9N54_19500	COG0534	Mate efflux family protein
K9N54_19505	COG0673	inositol 2-dehydrogenase activity
K9N54_19510	COG0784	Response regulator, receiver
K9N54_19510	COG2205	protein histidine kinase activity
K9N54_19510	COG5002	protein histidine kinase activity
K9N54_19535	COG1522	sequence-specific DNA binding
K9N54_19540	COG0531	amino acid
K9N54_19555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K9N54_19560	COG2239	Acts as a magnesium transporter
K9N54_19565	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K9N54_19570	COG0402	S-adenosylhomocysteine deaminase activity
K9N54_19580	COG1418	mRNA catabolic process
K9N54_19590	COG2814	Major facilitator Superfamily
K9N54_19600	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K9N54_19620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9N54_19635	COG4221	oxidoreductase activity
K9N54_19640	COG0745	RESPONSE REGULATOR receiver
K9N54_19645	COG2205	protein histidine kinase activity
K9N54_19655	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
K9N54_19660	COG2194	sulfuric ester hydrolase activity
K9N54_19665	COG0673	inositol 2-dehydrogenase activity
K9N54_19700	COG4667	esterase of the alpha-beta hydrolase superfamily
K9N54_19705	COG1741	Belongs to the pirin family
K9N54_19710	COG1278	Cold shock
K9N54_19725	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K9N54_19740	COG1686	Belongs to the peptidase S11 family
K9N54_19745	COG0625	glutathione transferase activity
K9N54_19755	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
K9N54_19770	COG1028	Short-chain dehydrogenase reductase Sdr
K9N54_19785	COG3746	phosphate-selective porin O and P
K9N54_19805	COG3833	ABC-type maltose transport systems, permease component
K9N54_19810	COG1175	transmembrane transport
K9N54_19820	COG3842	ATPase activity
K9N54_19825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K9N54_19850	COG0438	transferase activity, transferring glycosyl groups
K9N54_19880	COG3097	Belongs to the UPF0267 family
K9N54_19885	COG1309	transcriptional regulator
K9N54_19890	COG2130	NADP-dependent
K9N54_19900	COG0753	catalase activity
K9N54_19905	COG2084	Dehydrogenase
K9N54_19910	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9N54_19915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9N54_19925	COG2207	Transcriptional regulator
K9N54_19930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9N54_19930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9N54_19930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9N54_19945	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9N54_19950	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
K9N54_19955	COG3300	MHYT domain
K9N54_19955	COG5001	Diguanylate cyclase
K9N54_19960	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K9N54_19965	COG0569	domain protein
K9N54_19975	COG2205	protein histidine kinase activity
K9N54_19975	COG2205	protein histidine kinase activity
K9N54_19980	COG1132	(ABC) transporter
K9N54_19985	COG4774	siderophore transport
K9N54_19990	COG1120	ATPase activity
K9N54_19995	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K9N54_20025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9N54_20045	COG2197	response regulator
K9N54_20055	COG0840	transmembrane signaling receptor activity
K9N54_20060	COG0714	Associated with various cellular activities
K9N54_20080	COG2304	oxidoreductase activity
K9N54_20100	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K9N54_20105	COG0581	inorganic phosphate transmembrane transporter activity
K9N54_20110	COG0573	inorganic phosphate transmembrane transporter activity
K9N54_20140	COG4771	TonB-dependent receptor
K9N54_20145	COG1770	oligopeptidase
K9N54_20150	COG0513	Belongs to the DEAD box helicase family
K9N54_20160	COG1388	LysM domain
K9N54_20160	COG1376	ErfK ybiS ycfS ynhG family protein
K9N54_20165	COG0415	Belongs to the DNA photolyase family
K9N54_20170	COG0789	Transcriptional regulator
K9N54_20175	COG3272	Protein of unknown function (DUF1722)
K9N54_20180	COG0813	purine-nucleoside phosphorylase activity
K9N54_20195	COG3706	GGDEF domain
K9N54_20205	COG1566	PFAM secretion protein HlyD family protein
K9N54_20210	COG4720	Psort location CytoplasmicMembrane, score
K9N54_20215	COG1122	ATPase activity
K9N54_20230	COG0348	domain, Protein
K9N54_20235	COG0437	4 iron, 4 sulfur cluster binding
K9N54_20240	COG1247	-acetyltransferase
K9N54_20265	COG1067	ATP-dependent peptidase activity
K9N54_20275	COG4172	Belongs to the ABC transporter superfamily
K9N54_20280	COG1505	serine-type exopeptidase activity
K9N54_20285	COG0583	DNA-binding transcription factor activity
K9N54_20290	COG1620	l-lactate permease
K9N54_20295	COG1304	FMN binding
K9N54_20305	COG0668	transmembrane transport
K9N54_20340	COG1063	alcohol dehydrogenase
K9N54_20345	COG0156	8-amino-7-oxononanoate synthase activity
K9N54_20355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9N54_20375	COG0745	RESPONSE REGULATOR receiver
K9N54_20405	COG0346	lactoylglutathione lyase activity
K9N54_20425	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K9N54_20505	COG1987	bacterial-type flagellum assembly
K9N54_20515	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K9N54_20530	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K9N54_20535	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
K9N54_20540	COG1516	flagellar protein fliS
K9N54_20555	COG1580	Controls the rotational direction of flagella during chemotaxis
K9N54_20560	COG1191	sigma factor activity
K9N54_20565	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K9N54_20570	COG1360	Flagellar Motor Protein
K9N54_20600	COG1882	Formate acetyltransferase
K9N54_20605	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
K9N54_20610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K9N54_20620	COG0454	-acetyltransferase
K9N54_20630	COG2814	Major facilitator Superfamily
K9N54_20670	COG0628	permease
K9N54_20675	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
K9N54_20685	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9N54_20695	COG4628	conserved protein (DUF2132)
K9N54_20700	COG0583	DNA-binding transcription factor activity
K9N54_20725	COG1686	Belongs to the peptidase S11 family
K9N54_20740	COG1054	Belongs to the UPF0176 family
K9N54_20745	COG3397	chitin binding
K9N54_20750	COG4667	esterase of the alpha-beta hydrolase superfamily
K9N54_20755	COG2095	MarC family integral membrane protein
K9N54_20775	COG0489	protein tyrosine kinase activity
K9N54_20775	COG3206	protein involved in exopolysaccharide biosynthesis
K9N54_20790	COG0583	DNA-binding transcription factor activity
K9N54_20800	COG1301	dicarboxylic acid transport
K9N54_20805	COG3339	Conserved Protein
K9N54_20810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9N54_20815	COG0700	Nucleoside recognition
K9N54_20820	COG3366	ferrous iron transmembrane transporter activity
K9N54_20830	COG0366	Alpha amylase catalytic
K9N54_20835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K9N54_20840	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K9N54_20845	COG1640	4-alpha-glucanotransferase
K9N54_20850	COG0058	SHG alpha-glucan phosphorylase activity
K9N54_20855	COG2909	trisaccharide binding
K9N54_20870	COG1999	signal sequence binding
K9N54_20880	COG1263	PTS System
K9N54_20880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K9N54_20885	COG1162	GTPase activity
K9N54_20890	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
K9N54_20900	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
K9N54_20910	COG0531	amino acid
K9N54_20915	COG1982	Orn Lys Arg decarboxylase major
K9N54_20935	COG2356	endonuclease I
K9N54_20955	COG4580	involved in the transport of maltose and maltodextrins
K9N54_20980	COG0739	heme binding
K9N54_20990	COG0612	Peptidase, M16
K9N54_20995	COG0840	transmembrane signaling receptor activity
K9N54_21000	COG1120	ATPase activity
K9N54_21005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K9N54_21010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K9N54_21015	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
K9N54_21020	COG4772	TonB-dependent receptor
K9N54_21040	COG2814	Major facilitator Superfamily
K9N54_21045	COG4264	IucA IucC family
K9N54_21050	COG0019	diaminopimelate decarboxylase activity
K9N54_21055	COG1653	transport
K9N54_21080	COG0826	peptidase U32
K9N54_21085	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9N54_21090	COG1129	ABC transporter
K9N54_21095	COG1879	ABC-type sugar transport system periplasmic component
K9N54_21100	COG1069	ribulokinase activity
K9N54_21110	COG2160	L-arabinose isomerase activity
K9N54_21135	COG1764	response to oxidative stress
K9N54_21140	COG1846	Transcriptional regulator
K9N54_21150	COG3634	alkyl hydroperoxide reductase activity
K9N54_21175	COG1595	DNA-templated transcription, initiation
K9N54_21190	COG0583	DNA-binding transcription factor activity
K9N54_21195	COG1486	melibiose metabolic process
K9N54_21210	COG2258	MOSC domain
K9N54_21215	COG0513	Belongs to the DEAD box helicase family
K9N54_21225	COG2186	Transcriptional regulator
K9N54_21235	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K9N54_21245	COG0246	Mannitol dehydrogenase
K9N54_21255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K9N54_21260	COG0800	Aldolase
K9N54_21280	COG2207	Transcriptional regulator
K9N54_21290	COG1132	(ABC) transporter
K9N54_21335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9N54_21360	COG0259	pyridoxamine-phosphate oxidase activity
K9N54_21405	COG4166	transmembrane transport
K9N54_21420	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
K9N54_21425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K9N54_21425	COG1263	PTS System
K9N54_21430	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K9N54_21435	COG3340	Belongs to the peptidase S51 family
K9N54_21455	COG1444	tRNA N-acetyltransferase activity
K9N54_21480	COG4608	Belongs to the ABC transporter superfamily
K9N54_21485	COG0444	Belongs to the ABC transporter superfamily
K9N54_21495	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K9N54_21495	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
K9N54_21515	COG0217	transcriptional regulatory protein
K9N54_21520	COG0772	Belongs to the SEDS family
K9N54_21550	COG3275	phosphorelay sensor kinase activity
K9N54_21555	COG3279	Response regulator of the LytR AlgR family
K9N54_21565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K9N54_21590	COG0786	glutamate:sodium symporter activity
K9N54_21600	COG1131	(ABC) transporter
K9N54_21605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9N54_21610	COG0786	glutamate:sodium symporter activity
K9N54_21620	COG0363	glucosamine-6-phosphate deaminase activity
K9N54_21640	COG1741	Belongs to the pirin family
K9N54_21645	COG2259	Doxx family
K9N54_21655	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
K9N54_21660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K9N54_21670	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
K9N54_21710	COG3123	guanosine phosphorylase activity
K9N54_21720	COG5001	Diguanylate cyclase
K9N54_21725	COG0534	Mate efflux family protein
K9N54_21730	COG0564	pseudouridine synthase activity
K9N54_21745	COG0583	DNA-binding transcription factor activity
K9N54_21750	COG0561	phosphatase activity
K9N54_21760	COG2199	diguanylate cyclase activity
K9N54_21775	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K9N54_21780	COG2162	N-hydroxyarylamine O-acetyltransferase activity
K9N54_21785	COG0583	DNA-binding transcription factor activity
K9N54_21800	COG1414	Transcriptional regulator
K9N54_21805	COG1028	Short-chain dehydrogenase reductase Sdr
K9N54_21815	COG1917	Cupin 2, conserved barrel domain protein
K9N54_21830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K9N54_21835	COG0800	Aldolase
K9N54_21855	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9N54_21860	COG0823	Involved in the tonB-independent uptake of proteins
K9N54_21865	COG2375	cellular response to nickel ion
K9N54_21895	COG1357	PFAM Pentapeptide repeats (8 copies)
K9N54_21900	COG3047	cAMP biosynthetic process
K9N54_21930	COG3408	Glycogen debranching enzyme
K9N54_21930	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
K9N54_21935	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
K9N54_21945	COG0583	DNA-binding transcription factor activity
K9N54_21955	COG0583	DNA-binding transcription factor activity
K9N54_21970	COG0546	phosphoglycolate phosphatase activity
K9N54_21995	COG3835	regulator
K9N54_22000	COG2610	gluconate transmembrane transporter activity
K9N54_22005	COG1929	Belongs to the glycerate kinase type-1 family
K9N54_22010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9N54_22030	COG0454	-acetyltransferase
K9N54_22030	COG0456	acetyltransferase
K9N54_22045	COG1028	Short-chain dehydrogenase reductase Sdr
K9N54_22055	COG3005	denitrification pathway
K9N54_22060	COG0243	molybdopterin cofactor binding
K9N54_22070	COG0352	thiamine-phosphate diphosphorylase activity
K9N54_22075	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
K9N54_22080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K9N54_22085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9N54_22090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9N54_22095	COG1116	anion transmembrane transporter activity
K9N54_22100	COG0351	phosphomethylpyrimidine kinase
K9N54_22105	COG0312	modulator of DNA gyrase
K9N54_22110	COG0312	modulator of DNA gyrase
K9N54_22115	COG1901	pseudouridine methyltransferase
K9N54_22170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K9N54_22180	COG0584	glycerophosphoryl diester phosphodiesterase
K9N54_22185	COG0039	L-malate dehydrogenase activity
K9N54_22190	COG0745	RESPONSE REGULATOR receiver
K9N54_22210	COG0811	peptide transport
K9N54_22215	COG0811	peptide transport
K9N54_22220	COG0848	biopolymer transport protein
K9N54_22260	COG0803	Belongs to the bacterial solute-binding protein 9 family
K9N54_22265	COG1121	(ABC) transporter
K9N54_22270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K9N54_22285	COG1770	oligopeptidase
K9N54_22290	COG2814	Major facilitator Superfamily
K9N54_22295	COG0010	Belongs to the arginase family
K9N54_22300	COG1166	arginine decarboxylase activity
K9N54_22310	COG0189	ligase activity
K9N54_22310	COG4067	protein conserved in archaea
K9N54_22315	COG0189	ligase activity
K9N54_22320	COG0583	DNA-binding transcription factor activity
K9N54_22360	COG2199	diguanylate cyclase activity
K9N54_22380	COG0579	oxidoreductase
K9N54_22390	COG3033	Beta-eliminating lyase
K9N54_22405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
K9N54_22420	COG3706	GGDEF domain
K9N54_22425	COG0840	transmembrane signaling receptor activity
K9N54_22440	COG3706	GGDEF domain
K9N54_22445	COG0415	Belongs to the DNA photolyase family
K9N54_22450	COG3046	protein related to deoxyribodipyrimidine photolyase
K9N54_22465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9N54_22465	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9N54_22470	COG1765	OsmC-like protein
K9N54_22475	COG0110	maltose O-acetyltransferase activity
K9N54_22515	COG1011	Hydrolase
K9N54_22530	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
K9N54_22540	COG2067	long-chain fatty acid transport protein
K9N54_22545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9N54_22550	COG1136	(ABC) transporter
K9N54_22550	COG0577	efflux transmembrane transporter activity
K9N54_22560	COG3240	lipase activity
K9N54_22590	COG1609	Transcriptional regulator
K9N54_22595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9N54_22600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K9N54_22610	COG1840	ABC-type Fe3 transport system, periplasmic component
K9N54_22640	COG2842	Transposition protein
K9N54_22665	COG3081	Nucleoid-associated protein
K9N54_22690	COG3012	SEC-C Motif Domain Protein
K9N54_22905	COG2990	Protein conserved in bacteria
K9N54_22910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9N54_22915	COG2866	Carboxypeptidase
K9N54_22925	COG0583	DNA-binding transcription factor activity
K9N54_22950	COG1760	l-serine dehydratase
K9N54_22970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K9N54_22975	COG0741	lytic transglycosylase activity
K9N54_22995	COG1815	bacterial-type flagellum-dependent cell motility
K9N54_23000	COG1558	bacterial-type flagellum-dependent cell motility
K9N54_23005	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
K9N54_23010	COG1749	Flagellar hook protein flgE
K9N54_23015	COG4787	bacterial-type flagellum-dependent cell motility
K9N54_23020	COG4786	Flagellar basal body rod
K9N54_23025	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
K9N54_23030	COG1706	bacterial-type flagellum-dependent cell motility
K9N54_23040	COG4786	Flagellar basal body rod
K9N54_23040	COG1256	bacterial-type flagellum assembly
K9N54_23045	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
K9N54_23065	COG1304	FMN binding
K9N54_23090	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
K9N54_23095	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K9N54_23100	COG0459	protein refolding
K9N54_23115	COG1280	lysine exporter protein (LysE YggA)
K9N54_23135	COG1309	transcriptional regulator
K9N54_23145	COG0737	Belongs to the 5'-nucleotidase family
K9N54_23150	COG2070	2-Nitropropane dioxygenase
K9N54_23155	COG3537	Alpha-1,2-mannosidase
K9N54_23165	COG3537	Alpha-1,2-mannosidase
K9N54_23170	COG3537	Alpha-1,2-mannosidase
K9N54_23175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9N54_23200	COG1349	DNA-binding transcription factor activity
K9N54_23210	COG0753	catalase activity
K9N54_23220	COG1335	isochorismatase
K9N54_23230	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K9N54_23255	COG0583	DNA-binding transcription factor activity
K9N54_23270	COG3713	MltA-interacting MipA family protein
K9N54_23275	COG3015	lipoprotein NlpE involved in copper resistance
K9N54_23280	COG1342	Belongs to the UPF0251 family
K9N54_23310	COG4948	Mandelate Racemase Muconate Lactonizing
K9N54_23320	COG0583	DNA-binding transcription factor activity
K9N54_23355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9N54_23390	COG3842	ATPase activity
K9N54_23420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K9N54_23440	COG3706	GGDEF domain
K9N54_23460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9N54_23480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K9N54_23495	COG0574	Belongs to the PEP-utilizing enzyme family
K9N54_23495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K9N54_23500	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
K9N54_23505	COG0252	asparaginase activity
K9N54_23510	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K9N54_23515	COG0583	DNA-binding transcription factor activity
K9N54_23530	COG3122	Protein conserved in bacteria
K9N54_23540	COG1028	Short-chain dehydrogenase reductase Sdr
K9N54_23550	COG1063	alcohol dehydrogenase
K9N54_23555	COG1902	pentaerythritol trinitrate reductase activity
K9N54_23570	COG0583	DNA-binding transcription factor activity
K9N54_23580	COG0513	Belongs to the DEAD box helicase family
K9N54_23620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9N54_23625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K9N54_23625	COG2207	Transcriptional regulator
K9N54_23655	COG2354	Protein conserved in bacteria
K9N54_23660	COG0418	dihydroorotase activity
K9N54_23665	COG0401	homolog of Blt101
K9N54_23670	COG0633	Ferredoxin
K9N54_23670	COG3217	Mosc domain protein beta barrel domain protein
K9N54_23670	COG0633	Ferredoxin
K9N54_23670	COG3217	Mosc domain protein beta barrel domain protein
K9N54_23675	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K9N54_23680	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K9N54_23720	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
K9N54_23725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K9N54_23735	COG0848	biopolymer transport protein
K9N54_23740	COG0811	peptide transport
K9N54_23745	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
K9N54_23755	COG3721	Heme iron utilization protein
K9N54_23760	COG0748	coenzyme F420 binding
K9N54_23770	COG0784	Response regulator, receiver
K9N54_23770	COG0835	chemotaxis
K9N54_23775	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9N54_23785	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
K9N54_23785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9N54_23810	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K9N54_23815	COG0783	Belongs to the Dps family
K9N54_23820	COG0583	DNA-binding transcription factor activity
K9N54_23835	COG4934	collagen metabolic process
K9N54_23845	COG0366	Alpha amylase catalytic
K9N54_23865	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9N54_23870	COG0589	response to stress
K9N54_23875	COG0488	(ABC) transporter
K9N54_23880	COG1505	serine-type exopeptidase activity
K9N54_23890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9N54_23900	COG2067	long-chain fatty acid transport protein
K9N54_23910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K9N54_23940	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9N54_23960	COG3383	formate dehydrogenase (NAD+) activity
K9N54_23975	COG0842	Transport permease protein
K9N54_23980	COG1131	(ABC) transporter
K9N54_23990	COG0840	transmembrane signaling receptor activity
K9N54_23995	COG2706	6-phosphogluconolactonase activity
K9N54_24005	COG1881	PFAM PEBP family protein
K9N54_24015	COG0798	PFAM Bile acid sodium symporter
K9N54_24030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9N54_24035	COG2213	PTS system mannitol-specific
K9N54_24040	COG1063	alcohol dehydrogenase
K9N54_24050	COG1072	(Pantothenic acid kinase))
K9N54_24055	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
K9N54_24075	COG0814	amino acid
K9N54_24090	COG3314	Sporulation integral membrane protein YlbJ
K9N54_24110	COG0739	heme binding
K9N54_24115	COG5001	Diguanylate cyclase
K9N54_24120	COG0583	DNA-binding transcription factor activity
K9N54_24125	COG2814	Major facilitator Superfamily
K9N54_24140	COG0697	spore germination
K9N54_24145	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
K9N54_24170	COG2207	Transcriptional regulator
K9N54_24175	COG1280	lysine exporter protein (LysE YggA)
K9N54_24185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9N54_24190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K9N54_24200	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
K9N54_24225	COG1612	heme a metabolic process
K9N54_24230	COG0109	protoheme IX farnesyltransferase activity
K9N54_24235	COG0545	Peptidyl-prolyl cis-trans isomerase
K9N54_24265	COG1278	Cold shock
K9N54_24270	COG3036	rescue of stalled ribosome
K9N54_24280	COG2199	diguanylate cyclase activity
K9N54_24300	COG1136	(ABC) transporter
K9N54_24300	COG0577	efflux transmembrane transporter activity
K9N54_24310	COG0840	transmembrane signaling receptor activity
K9N54_24315	COG0783	Belongs to the Dps family
K9N54_24325	COG2133	pyrroloquinoline quinone binding
K9N54_24330	COG1454	alcohol dehydrogenase
K9N54_24335	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
K9N54_24375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K9N54_24380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9N54_24385	COG3186	Phenylalanine-4-hydroxylase
K9N54_24390	COG2154	pterin-4-alpha-carbinolamine dehydratase
K9N54_24410	COG3530	Putative quorum-sensing-regulated virulence factor
K9N54_24415	COG0513	Belongs to the DEAD box helicase family
K9N54_24420	COG4628	conserved protein (DUF2132)
K9N54_24425	COG0133	tryptophan synthase activity
K9N54_24435	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
K9N54_24445	COG0523	cobalamin synthesis protein
K9N54_24450	COG0513	Belongs to the DEAD box helicase family
K9N54_24470	COG2200	EAL domain
K9N54_24475	COG1119	ATPase activity
K9N54_24480	COG0840	transmembrane signaling receptor activity
K9N54_24500	COG0641	radical SAM
K9N54_24520	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K9N54_24535	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
K9N54_24540	COG0513	Belongs to the DEAD box helicase family
K9N54_24545	COG5001	Diguanylate cyclase
K9N54_24550	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K9N54_24565	COG5413	integral membrane protein
K9N54_24575	COG1024	Enoyl-CoA hydratase
K9N54_24580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K9N54_24585	COG1960	acyl-CoA dehydrogenase activity
K9N54_24595	COG0183	Belongs to the thiolase family
K9N54_24610	COG1024	Enoyl-CoA hydratase
K9N54_24615	COG1024	Enoyl-CoA hydratase
K9N54_24625	COG1028	Short-chain dehydrogenase reductase Sdr
K9N54_24630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K9N54_24635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K9N54_24640	COG1845	cytochrome c oxidase, subunit III
K9N54_24645	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
K9N54_24650	COG0109	protoheme IX farnesyltransferase activity
K9N54_24660	COG1902	pentaerythritol trinitrate reductase activity
K9N54_24690	COG1126	abc transporter atp-binding protein
K9N54_24695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9N54_24700	COG4215	(ABC) transporter
K9N54_24705	COG4160	amino acid transport
K9N54_24720	COG0625	glutathione transferase activity
K9N54_24755	COG0443	Heat shock 70 kDa protein
K9N54_24760	COG2847	Copper chaperone PCu(A)C
K9N54_24780	COG4607	ABC-type enterochelin transport system periplasmic component
K9N54_24785	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K9N54_24790	COG4605	iron ion homeostasis
K9N54_24795	COG4604	ABC transporter, ATP-binding protein
K9N54_24800	COG0789	Transcriptional regulator
K9N54_24810	COG4771	TonB-dependent receptor
K9N54_24810	COG1629	transport
K9N54_24840	COG1289	transmembrane transporter activity
K9N54_24845	COG0210	DNA helicase
K9N54_24850	COG1803	Methylglyoxal synthase
K9N54_24855	COG1879	ABC-type sugar transport system periplasmic component
K9N54_24860	COG2205	protein histidine kinase activity
K9N54_24860	COG0784	Response regulator, receiver
K9N54_24860	COG2198	Histidine kinase
K9N54_24875	COG0745	RESPONSE REGULATOR receiver
K9N54_24880	COG3119	arylsulfatase activity
K9N54_24885	COG3119	arylsulfatase activity
K9N54_24900	COG3119	arylsulfatase activity
K9N54_24905	COG0641	radical SAM
K9N54_24910	COG0714	Associated with various cellular activities
K9N54_24940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9N54_24945	COG0583	DNA-binding transcription factor activity
K9N54_24950	COG1597	lipid kinase activity
K9N54_24955	COG3111	PFAM Bacterial OB fold (BOF) protein
K9N54_24970	COG0641	radical SAM
K9N54_24995	COG0501	Belongs to the peptidase M48B family
K9N54_25000	COG1704	LemA family
K9N54_25005	COG3069	C4-dicarboxylate transmembrane transporter activity
K9N54_25015	COG1214	PFAM Peptidase M22, glycoprotease
K9N54_25015	COG0456	acetyltransferase
K9N54_25035	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
K9N54_25055	COG2207	Transcriptional regulator
K9N54_25080	COG4964	Belongs to the GSP D family
K9N54_25140	COG0583	DNA-binding transcription factor activity
K9N54_25145	COG0583	DNA-binding transcription factor activity
K9N54_25160	COG5001	Diguanylate cyclase
K9N54_25160	COG3300	MHYT domain
K9N54_25165	COG2197	response regulator
K9N54_25170	COG3706	GGDEF domain
K9N54_25180	COG2197	response regulator
K9N54_25200	COG0835	chemotaxis
K9N54_25200	COG0784	Response regulator, receiver
K9N54_25215	COG2962	Rard protein
K9N54_25225	COG0671	phosphoesterase, PA-phosphatase related
K9N54_25270	COG0471	metal ion transport
K9N54_25275	COG3290	protein histidine kinase activity
K9N54_25280	COG4565	transcriptional regulatory protein
K9N54_25295	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
K9N54_25300	COG5642	Protein of unknown function (DUF2384)
K9N54_25320	COG1902	pentaerythritol trinitrate reductase activity
K9N54_25325	COG0346	lactoylglutathione lyase activity
K9N54_25345	COG2239	Acts as a magnesium transporter
K9N54_25460	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K9N54_25570	COG3504	Conjugal transfer protein
K9N54_25590	COG4962	Type ii secretion system protein e
K9N54_25600	COG3451	type IV secretory pathway VirB4
K9N54_25605	COG5268	conjugation
K9N54_25640	COG1192	Involved in chromosome partitioning
K9N54_25675	COG5492	domain, Protein
K9N54_25675	COG4932	domain protein
K9N54_25715	COG2885	chlorophyll binding
K9N54_25765	COG2337	Toxic component of a toxin-antitoxin (TA) module
K9N54_25775	COG4974	Belongs to the 'phage' integrase family
K9N54_25795	COG5492	domain, Protein
K9N54_25795	COG4932	domain protein
K9N54_25815	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
K9N54_25830	COG0739	heme binding
K9N54_26215	COG0419	ATPase involved in DNA repair
K9N54_26240	COG1192	Involved in chromosome partitioning
K9N54_26270	COG5268	conjugation
K9N54_26275	COG3451	type IV secretory pathway VirB4
K9N54_26285	COG4962	Type ii secretion system protein e
K9N54_26300	COG3504	Conjugal transfer protein