locus-tag	class	description
Vp2S01_0001	ENOG4105QTB	Flavodoxin
Vp2S01_0002	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Vp2S01_0003	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Vp2S01_0004	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Vp2S01_0007	ENOG4105E5Q	amino acid AbC transporter
Vp2S01_0008	ENOG4105EAB	amino acid AbC transporter
Vp2S01_0010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Vp2S01_0011	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Vp2S01_0012	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Vp2S01_0013	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Vp2S01_0017	ENOG4108ZNX	Heat shock protein
Vp2S01_0018	ENOG4105JKW	Valine--pyruvate aminotransferase
Vp2S01_0019	ENOG4107T9C	Alpha amylase catalytic region
Vp2S01_0020	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Vp2S01_0021	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
Vp2S01_0025	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
Vp2S01_0028	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
Vp2S01_0029	ENOG4105CHU	acetyl-coa acetyltransferase
Vp2S01_0030	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Vp2S01_0031	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Vp2S01_0032	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Vp2S01_0033	ENOG4108RR8	protoporphyrinogen oxidase
Vp2S01_0038	ENOG4105WMR	Protein CrcB homolog
Vp2S01_0039	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Vp2S01_0041	ENOG4105D06	uba thif-type nad fad binding protein
Vp2S01_0042	ENOG4105WHD	thiamine biosynthesis protein ThiS
Vp2S01_0043	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Vp2S01_0044	ENOG4105D41	biosynthesis protein thiH
Vp2S01_0045	ENOG4105DC7	peptidase M24
Vp2S01_0045	ENOG4105DC7	peptidase M24
Vp2S01_0051	ENOG4105E18	UPF0276 protein
Vp2S01_0053	ENOG4105C4R	Atp-dependent dna helicase
Vp2S01_0054	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Vp2S01_0057	ENOG4105FR1	rard protein
Vp2S01_0058	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Vp2S01_0060	ENOG4105EX9	Membrane
Vp2S01_0061	ENOG4105C9X	ppx gppa phosphatase
Vp2S01_0062	ENOG4105C1J	atp-dependent rna helicase
Vp2S01_0063	ENOG4105K63	Thioredoxin
Vp2S01_0064	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Vp2S01_0066	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Vp2S01_0067	ENOG4108ZIT	Ferredoxin, 2FE-2S
Vp2S01_0068	ENOG4107QK7	reductase
Vp2S01_0073	ENOG410601J	HemY protein
Vp2S01_0074	ENOG4105ECF	c-methyltransferase
Vp2S01_0075	ENOG41076E6	Uroporphyrinogen-III Synthase
Vp2S01_0076	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Vp2S01_0077	ENOG4107T0K	Adenylate cyclase
Vp2S01_0078	ENOG4105XQ6	frataxin-like protein
Vp2S01_0080	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Vp2S01_0081	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Vp2S01_0083	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Vp2S01_0084	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
Vp2S01_0085	ENOG4105BZU	Histidine kinase
Vp2S01_0086	ENOG4106IUH	DTW domain containing protein
Vp2S01_0089	ENOG4105DQF	Hydrolase
Vp2S01_0090	ENOG4108EUD	Lysophospholipase
Vp2S01_0091	ENOG410829K	Lysine exporter protein (Lyse ygga)
Vp2S01_0092	ENOG4105D58	Diguanylate phosphodiesterase
Vp2S01_0093	ENOG41082YX	Transcriptional regulator, arsr family
Vp2S01_0094	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Vp2S01_0105	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
Vp2S01_0107	ENOG4106H78	methyltransferase
Vp2S01_0108	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Vp2S01_0109	ENOG4105CAK	Cell division ATP-binding protein ftsE
Vp2S01_0110	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Vp2S01_0111	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Vp2S01_0112	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
Vp2S01_0113	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
Vp2S01_0114	ENOG4105X6C	Flagellar basal body-associated protein FliL
Vp2S01_0115	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
Vp2S01_0116	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
Vp2S01_0117	ENOG4105E55	glycerol-3-phosphate acyltransferase
Vp2S01_0118	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Vp2S01_0120	ENOG4107R73	Mate efflux family protein
Vp2S01_0121	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
Vp2S01_0124	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
Vp2S01_0125	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Vp2S01_0127	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Vp2S01_0136	ENOG4105JIM	Phosphatidylserine synthase
Vp2S01_0138	ENOG4105D4A	Cell wall formation (By similarity)
Vp2S01_0139	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Vp2S01_0140	ENOG4105CS9	pantothenic acid kinase
Vp2S01_0142	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Vp2S01_0143	ENOG4105PM1	preprotein translocase subunit SecE
Vp2S01_0144	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Vp2S01_0145	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Vp2S01_0146	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Vp2S01_0147	ENOG4108VZM	50s ribosomal protein L10
Vp2S01_0148	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Vp2S01_0149	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Vp2S01_0150	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Vp2S01_0151	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
Vp2S01_0152	ENOG4105E09	nadh pyrophosphatase
Vp2S01_0155	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Vp2S01_0156	ENOG4108RG0	uracil-dna glycosylase
Vp2S01_0157	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
Vp2S01_0158	ENOG4105R2J	Conserved Protein
Vp2S01_0162	ENOG4105C12	Phosphoribosylglycinamide synthetase
Vp2S01_0163	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Vp2S01_0165	ENOG4105W1Y	Transcriptional regulator
Vp2S01_0167	ENOG4108M3R	transcriptional activator CadC
Vp2S01_0168	ENOG4105D5Q	Arginine ornithine antiporter
Vp2S01_0169	ENOG4105CXN	decarboxylase
Vp2S01_0179	ENOG4105BZU	Histidine kinase
Vp2S01_0180	ENOG4105C5H	ABC transporter
Vp2S01_0181	ENOG4107XZQ	multidrug resistance protein
Vp2S01_0182	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
Vp2S01_0183	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Vp2S01_0184	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Vp2S01_0185	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Vp2S01_0186	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
Vp2S01_0187	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Vp2S01_0188	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Vp2S01_0191	ENOG4105D8G	Major Facilitator superfamily
Vp2S01_0192	ENOG4105BZU	Histidine kinase
Vp2S01_0193	ENOG4105C9Q	fumarate hydratase class II
Vp2S01_0196	ENOG4107QN1	sodium solute
Vp2S01_0198	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
Vp2S01_0200	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
Vp2S01_0201	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
Vp2S01_0202	ENOG4108IJ0	Aspartate ammonia-lyase
Vp2S01_0203	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
Vp2S01_0204	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Vp2S01_0206	ENOG4105E0F	Histidine kinase
Vp2S01_0207	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Vp2S01_0208	ENOG4108SPG	Periplasmic Protein
Vp2S01_0209	ENOG41076HS	cation diffusion facilitator family transporter
Vp2S01_0210	ENOG4105CTQ	phosphohexokinase
Vp2S01_0211	ENOG4107QI1	Mate efflux family protein
Vp2S01_0212	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Vp2S01_0213	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Vp2S01_0216	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Vp2S01_0218	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
Vp2S01_0219	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Vp2S01_0221	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
Vp2S01_0222	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
Vp2S01_0223	ENOG4105E33	succinate dehydrogenase
Vp2S01_0226	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
Vp2S01_0228	ENOG41062JF	Transcriptional regulator
Vp2S01_0230	ENOG41063SB	peptidase
Vp2S01_0231	ENOG4105D7W	serine acetyltransferase
Vp2S01_0232	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Vp2S01_0233	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
Vp2S01_0234	ENOG4107YZP	Rhodanese domain protein
Vp2S01_0236	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Vp2S01_0238	ENOG4108NVR	Methyl-accepting chemotaxis
Vp2S01_0240	ENOG4105C8P	)-transporter
Vp2S01_0241	ENOG4105DJ4	phosphatidylserine decarboxylase
Vp2S01_0242	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Vp2S01_0243	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
Vp2S01_0244	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Vp2S01_0245	ENOG4105K8N	protein family UPF0079, ATPase
Vp2S01_0246	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Vp2S01_0247	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Vp2S01_0248	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Vp2S01_0249	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Vp2S01_0250	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Vp2S01_0251	ENOG4107QJR	hflk protein
Vp2S01_0252	ENOG4105EPW	hflc protein
Vp2S01_0254	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Vp2S01_0255	ENOG4108UV7	flagellar protein motX
Vp2S01_0256	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
Vp2S01_0257	ENOG4105KPV	Transcriptional regulator
Vp2S01_0258	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Vp2S01_0259	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Vp2S01_0260	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Vp2S01_0261	ENOG4105C31	Tryptophanyl-tRNA synthetase
Vp2S01_0266	ENOG4105C8Y	Acetylornithine aminotransferase
Vp2S01_0268	ENOG4105C26	Dehydrogenase
Vp2S01_0270	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
Vp2S01_0271	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
Vp2S01_0272	ENOG4105YP7	UPF0270 protein
Vp2S01_0273	ENOG4105DNZ	Alpha Beta Hydrolase
Vp2S01_0275	ENOG4105C5H	ABC transporter
Vp2S01_0276	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
Vp2S01_0279	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Vp2S01_0280	ENOG4105D44	asparaginase
Vp2S01_0281	ENOG41069P5	Protein slyX homolog
Vp2S01_0283	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Vp2S01_0284	ENOG4105WWK	YheO domain protein
Vp2S01_0285	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
Vp2S01_0286	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
Vp2S01_0287	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
Vp2S01_0288	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Vp2S01_0289	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Vp2S01_0290	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Vp2S01_0291	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Vp2S01_0292	ENOG4108UQY	Iron-storage protein
Vp2S01_0293	ENOG4105C6K	Malic enzyme
Vp2S01_0294	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
Vp2S01_0295	ENOG4105C28	cystathionine
Vp2S01_0296	ENOG4105CFH	Aspartokinase
Vp2S01_0297	ENOG4105SYT	Methylenetetrahydrofolate reductase
Vp2S01_0300	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Vp2S01_0301	ENOG4105CWC	Acetylornithine deacetylase
Vp2S01_0302	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Vp2S01_0303	ENOG4105CAS	nag kinase
Vp2S01_0304	ENOG4105CDH	Citrulline--aspartate ligase
Vp2S01_0305	ENOG4105CH7	arginosuccinase
Vp2S01_0307	ENOG4105EHV	domain protein
Vp2S01_0309	ENOG4108JQC	penicillin-binding protein 1A
Vp2S01_0314	ENOG4105E4G	Type IV pilus
Vp2S01_0315	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Vp2S01_0316	ENOG4105D49	3-dehydroquinate synthase
Vp2S01_0318	ENOG4105DFE	Dna adenine methylase
Vp2S01_0319	ENOG4105DJV	ribulose-phosphate 3-epimerase
Vp2S01_0320	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Vp2S01_0321	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Vp2S01_0322	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Vp2S01_0324	ENOG4105CDU	Replicative dna helicase
Vp2S01_0325	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Vp2S01_0327	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Vp2S01_0328	ENOG4107QP8	phosphohexose isomerase
Vp2S01_0330	ENOG4105MYN	Zinc uptake regulation protein
Vp2S01_0332	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Vp2S01_0336	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
Vp2S01_0337	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
Vp2S01_0338	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
Vp2S01_0348	ENOG4105EEQ	Na H antiporter
Vp2S01_0349	ENOG4105C3R	Methionine synthase
Vp2S01_0350	ENOG4105CFH	Aspartokinase
Vp2S01_0352	ENOG4105C5R	Aminotransferase
Vp2S01_0354	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Vp2S01_0355	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Vp2S01_0356	ENOG41086KC	Transcriptional regulator
Vp2S01_0357	ENOG4108UUM	single-stranded DNA-binding protein
Vp2S01_0358	ENOG41062P1	Diguanylate cyclase phosphodiesterase
Vp2S01_0362	ENOG4105E4G	Type IV pilus
Vp2S01_0365	ENOG4107QHF	type ii secretion system protein e
Vp2S01_0366	ENOG4105D7Q	type ii secretion system
Vp2S01_0376	ENOG4105DFF	Rod shape-determining protein mreb
Vp2S01_0377	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
Vp2S01_0378	ENOG4105VQ7	Rod shape-determining protein MreD
Vp2S01_0379	ENOG4108Z03	MAF-like protein
Vp2S01_0380	ENOG4105C03	ribonuclease
Vp2S01_0381	ENOG4105QD6	exported protein
Vp2S01_0383	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Vp2S01_0384	ENOG4108IAB	Phoh family
Vp2S01_0385	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
Vp2S01_0386	ENOG4105K3M	)-transporter
Vp2S01_0388	ENOG4105D3G	Pseudouridine synthase
Vp2S01_0389	ENOG4105C5I	Dehydrogenase
Vp2S01_0390	ENOG4105N42	UPF0307 protein
Vp2S01_0391	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Vp2S01_0392	ENOG4105CJW	magnesium transporter
Vp2S01_0393	ENOG41080Z8	PHOSPHOCARRIER protein
Vp2S01_0394	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Vp2S01_0395	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
Vp2S01_0396	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
Vp2S01_0397	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Vp2S01_0398	ENOG4108IUZ	ABC transporter
Vp2S01_0399	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
Vp2S01_0401	ENOG4105C2X	Arabinose 5-phosphate isomerase
Vp2S01_0403	ENOG4105DHJ	ABC, transporter
Vp2S01_0404	ENOG4105CY3	ABC transporter, permease
Vp2S01_0405	ENOG4107PE3	Mammalian cell entry related domain protein
Vp2S01_0406	ENOG4105E3I	toluene tolerance
Vp2S01_0408	ENOG4105VFK	BolA family
Vp2S01_0409	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Vp2S01_0410	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
Vp2S01_0411	ENOG4105KME	endoribonuclease L-psp
Vp2S01_0412	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
Vp2S01_0413	ENOG4105CXT	aspartate transcarbamylase
Vp2S01_0414	ENOG4105DBV	ornithine carbamoyltransferase
Vp2S01_0415	ENOG4105CEU	Arginine dihydrolase
Vp2S01_0418	ENOG4108MJ3	acetyltransferase
Vp2S01_0420	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Vp2S01_0421	ENOG4105MYG	DNA polymerase iii, chi subunit
Vp2S01_0422	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Vp2S01_0423	ENOG4108M8S	permease YjgP YjgQ family protein
Vp2S01_0424	ENOG4108K5H	permease YjgP YjgQ family protein
Vp2S01_0426	ENOG4105EXU	Membrane
Vp2S01_0427	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
Vp2S01_0428	ENOG41062JF	Transcriptional regulator
Vp2S01_0434	ENOG4105CK1	PTS System
Vp2S01_0435	ENOG4105VCP	PTS System
Vp2S01_0436	ENOG4105F8D	glycoside hydrolase family 4
Vp2S01_0437	ENOG410901P	UPF0249 protein
Vp2S01_0439	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Vp2S01_0444	ENOG4105C26	Dehydrogenase
Vp2S01_0445	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_0446	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
Vp2S01_0447	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
Vp2S01_0448	ENOG4105CEN	a g-specific adenine glycosylase
Vp2S01_0449	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Vp2S01_0451	ENOG4105CSV	Glutaminase
Vp2S01_0452	ENOG4105CSA	Coproporphyrinogen iii oxidase
Vp2S01_0453	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Vp2S01_0455	ENOG4105VZ9	UPF0235 protein
Vp2S01_0456	ENOG4108VIA	integral membrane protein
Vp2S01_0457	ENOG4105II7	pyrroline-5-carboxylate reductase
Vp2S01_0458	ENOG4105DFA	alanine racemase domain protein
Vp2S01_0459	ENOG4105CZX	twitching motility protein
Vp2S01_0460	ENOG4105CZX	twitching motility protein
Vp2S01_0461	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Vp2S01_0462	ENOG4108UJU	UPF0301 protein
Vp2S01_0463	ENOG4105D7Z	glutathione synthase
Vp2S01_0464	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Vp2S01_0465	ENOG4105RWS	endonuclease I
Vp2S01_0466	ENOG4105GPY	SprT protein
Vp2S01_0468	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Vp2S01_0470	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Vp2S01_0471	ENOG4108R4R	Iron-regulated virulence regulatory protein
Vp2S01_0472	ENOG4105D05	Receptor
Vp2S01_0473	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Vp2S01_0475	ENOG4105BZA	Phosphoglycerate kinase
Vp2S01_0476	ENOG4105D2N	Aldolase
Vp2S01_0477	ENOG4105D64	Mechanosensitive ion channel
Vp2S01_0478	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
Vp2S01_0480	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
Vp2S01_0481	ENOG4105MPN	Membrane
Vp2S01_0482	ENOG4108JQ1	Dehydrogenase
Vp2S01_0483	ENOG4105E66	phosphoriboisomerase A
Vp2S01_0484	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Vp2S01_0485	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
Vp2S01_0487	ENOG4105D0A	hydroxylase
Vp2S01_0488	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
Vp2S01_0490	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
Vp2S01_0491	ENOG4105Y75	tpr repeat protein
Vp2S01_0492	ENOG4108IYU	L-aspartate oxidase
Vp2S01_0493	ENOG4105EMN	RNA polymerase sigma factor
Vp2S01_0494	ENOG41069PW	sigma-e factor negative regulatory protein
Vp2S01_0497	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Vp2S01_0498	ENOG4105C3F	Signal peptidase i
Vp2S01_0499	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Vp2S01_0500	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Vp2S01_0501	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
Vp2S01_0502	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
Vp2S01_0503	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Vp2S01_0504	ENOG4105BZU	Histidine kinase
Vp2S01_0505	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Vp2S01_0506	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Vp2S01_0507	ENOG4105DXN	mazG family
Vp2S01_0508	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Vp2S01_0509	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Vp2S01_0510	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
Vp2S01_0511	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Vp2S01_0512	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Vp2S01_0513	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
Vp2S01_0514	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Vp2S01_0515	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Vp2S01_0517	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Vp2S01_0518	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Vp2S01_0519	ENOG4107TH8	cina domain protein
Vp2S01_0520	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Vp2S01_0521	ENOG4105Y3E	Modulates RecA activity (By similarity)
Vp2S01_0522	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Vp2S01_0523	ENOG4105CFH	Aspartokinase
Vp2S01_0524	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
Vp2S01_0527	ENOG4107QSA	Oxaloacetate decarboxylase
Vp2S01_0528	ENOG4105D9Q	decarboxylase (Beta subunit)
Vp2S01_0529	ENOG4105CPQ	Dehydrogenase
Vp2S01_0530	ENOG4105W39	Membrane
Vp2S01_0532	ENOG4105D9M	gamma-glutamylcysteine synthetase
Vp2S01_0534	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
Vp2S01_0535	ENOG4108JU6	CBS domain protein
Vp2S01_0536	ENOG4106KVJ	cytochrome C assembly protein
Vp2S01_0537	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Vp2S01_0538	ENOG4105K5M	30s ribosomal protein S16
Vp2S01_0539	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Vp2S01_0540	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Vp2S01_0541	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Vp2S01_0542	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
Vp2S01_0543	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
Vp2S01_0544	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Vp2S01_0545	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
Vp2S01_0546	ENOG4105D7Q	type ii secretion system
Vp2S01_0547	ENOG4107QHF	type ii secretion system protein e
Vp2S01_0549	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Vp2S01_0551	ENOG41073TP	transcriptional regulator
Vp2S01_0552	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
Vp2S01_0553	ENOG4107QSN	dihydrolipoamide acetyltransferase
Vp2S01_0554	ENOG4107QN2	dihydrolipoyl dehydrogenase
Vp2S01_0555	ENOG410630P	Transcriptional regulator
Vp2S01_0556	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Vp2S01_0557	ENOG41077A9	carbonic anhydrase
Vp2S01_0558	ENOG4105CHH	sulfate transporter
Vp2S01_0559	ENOG4105DA5	(ABC) transporter
Vp2S01_0560	ENOG4105E3A	(ABC) transporter
Vp2S01_0561	ENOG4105D1S	lipid A biosynthesis
Vp2S01_0562	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Vp2S01_0563	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Vp2S01_0564	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vp2S01_0565	ENOG4105DJ0	Poly(A) Polymerase
Vp2S01_0566	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
Vp2S01_0567	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Vp2S01_0568	ENOG4105PW4	Sugar fermentation stimulation protein homolog
Vp2S01_0569	ENOG4105CQ7	ATP-dependent helicase
Vp2S01_0570	ENOG4105BZ4	penicillin-binding protein
Vp2S01_0571	ENOG4105D78	K07001 NTE family protein
Vp2S01_0572	ENOG4107QIJ	Aconitate hydratase 2
Vp2S01_0573	ENOG4105XTV	UPF0231 protein
Vp2S01_0574	ENOG4108YZA	Nitrogen regulatory protein pii
Vp2S01_0578	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_0581	ENOG4105E2D	ec 3.2.1.52
Vp2S01_0582	ENOG4105RD7	BadF BadG BcrA BcrD
Vp2S01_0584	ENOG4108JQ7	(ABC) transporter
Vp2S01_0585	ENOG4105C3U	ABC transporter
Vp2S01_0586	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Vp2S01_0588	ENOG4107QRA	Extracellular solute-binding protein, family 5
Vp2S01_0589	ENOG4105BZU	Histidine kinase
Vp2S01_0590	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
Vp2S01_0591	ENOG4105IPI	Membrane
Vp2S01_0594	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Vp2S01_0595	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
Vp2S01_0597	ENOG4105BZS	acriflavin resistance protein
Vp2S01_0598	ENOG4105DR5	peptidase
Vp2S01_0599	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Vp2S01_0601	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
Vp2S01_0602	ENOG4107QE9	Inherit from COG: Membrane
Vp2S01_0603	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Vp2S01_0604	ENOG4105HBR	Rna-binding protein
Vp2S01_0605	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Vp2S01_0606	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Vp2S01_0607	ENOG4105EEI	dihydropteroate synthase
Vp2S01_0608	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Vp2S01_0610	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Vp2S01_0611	ENOG4105CHV	Transcription elongation factor NusA
Vp2S01_0612	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Vp2S01_0613	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Vp2S01_0614	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Vp2S01_0615	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Vp2S01_0616	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Vp2S01_0619	ENOG4105C3S	Mate efflux family protein
Vp2S01_0620	ENOG4106RZ4	Peptidase U32
Vp2S01_0621	ENOG4105CFP	Peptidase U32
Vp2S01_0622	ENOG4105BZU	Histidine kinase
Vp2S01_0623	ENOG4105XPQ	lipid carrier protein
Vp2S01_0624	ENOG4108YYD	acetyltransferase
Vp2S01_0628	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Vp2S01_0630	ENOG4105EYA	deoxyribonuclease
Vp2S01_0631	ENOG4105D9N	nucleoside
Vp2S01_0632	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Vp2S01_0633	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
Vp2S01_0634	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
Vp2S01_0635	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
Vp2S01_0637	ENOG4105EAC	phosphoserine phosphatase
Vp2S01_0639	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Vp2S01_0640	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Vp2S01_0641	ENOG4105ETT	transcriptional Regulator, LysR family
Vp2S01_0643	ENOG4108IQE	Amp-dependent synthetase and ligase
Vp2S01_0661	ENOG41064T2	transcriptional regulator, lysR family
Vp2S01_0662	ENOG4105E5D	amino acid
Vp2S01_0663	ENOG4105FK9	beta-D-galactosidase beta subunit
Vp2S01_0664	ENOG4105CNT	hydrolase family 2
Vp2S01_0665	ENOG4105CQ4	Transcriptional regulator
Vp2S01_0666	ENOG4105CMR	udp-glucose 4-epimerase
Vp2S01_0667	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
Vp2S01_0668	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Vp2S01_0669	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
Vp2S01_0670	ENOG4105ETE	Transcriptional regulator (LacI family
Vp2S01_0672	ENOG4105CT4	transporter
Vp2S01_0673	ENOG41060NJ	transcriptional regulator
Vp2S01_0674	ENOG4108Y51	tRNA-binding protein
Vp2S01_0677	ENOG4107RX3	Mg2 transporter protein cora family protein
Vp2S01_0678	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
Vp2S01_0679	ENOG4105E98	transcriptional regulator DeoR family
Vp2S01_0680	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Vp2S01_0681	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Vp2S01_0683	ENOG4105CXY	transporter
Vp2S01_0684	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
Vp2S01_0685	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
Vp2S01_0686	ENOG4105X2V	dna damage-inducible protein
Vp2S01_0687	ENOG4105EVZ	LysR family transcriptional regulator
Vp2S01_0689	ENOG4105E68	Sulfatase
Vp2S01_0690	ENOG4105DSY	exodeoxyribonuclease V, gamma
Vp2S01_0691	ENOG4107QKA	exodeoxyribonuclease V beta
Vp2S01_0692	ENOG4107QYX	exodeoxyribonuclease v alpha
Vp2S01_0694	ENOG4107QZM	n-acetylglutamate synthase
Vp2S01_0696	ENOG4105CA3	membrane-bound lytic murein transglycosylase
Vp2S01_0697	ENOG4105CUZ	uba thif-type nad fad binding protein
Vp2S01_0698	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
Vp2S01_0699	ENOG4105BZU	Histidine kinase
Vp2S01_0700	ENOG4105C9B	Cysteine desulfurase
Vp2S01_0701	ENOG4107S0N	DJ-1 family
Vp2S01_0702	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Vp2S01_0707	ENOG4105K6V	RNA polymerase
Vp2S01_0710	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Vp2S01_0711	ENOG4105IEY	(LipO)protein
Vp2S01_0712	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
Vp2S01_0713	ENOG4105M85	Bola protein
Vp2S01_0714	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
Vp2S01_0715	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
Vp2S01_0716	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
Vp2S01_0717	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
Vp2S01_0718	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
Vp2S01_0719	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
Vp2S01_0720	ENOG4105CJ2	(LipO)protein
Vp2S01_0723	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Vp2S01_0724	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Vp2S01_0728	ENOG4105C8J	)-transporter
Vp2S01_0730	ENOG4105W1I	UPF0253 protein
Vp2S01_0732	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Vp2S01_0733	ENOG4108R96	Methyltransferase, YaeB family
Vp2S01_0734	ENOG4105NRA	50s ribosomal protein l31 type b
Vp2S01_0736	ENOG4105CFC	Transporter
Vp2S01_0737	ENOG4108UPT	UPF0178 protein
Vp2S01_0741	ENOG4105WP7	tRNA pseudouridine synthase C
Vp2S01_0742	ENOG4105DR9	pseudouridine synthase
Vp2S01_0743	ENOG4108T8E	UPF0325 protein
Vp2S01_0744	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
Vp2S01_0745	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Vp2S01_0746	ENOG4105CE9	30S ribosomal protein S2
Vp2S01_0747	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Vp2S01_0748	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Vp2S01_0749	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Vp2S01_0750	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Vp2S01_0751	ENOG4105KNE	Phosphatidate cytidylyltransferase
Vp2S01_0752	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Vp2S01_0753	ENOG4105DZP	Membrane-associated zinc metalloprotease
Vp2S01_0755	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
Vp2S01_0756	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Vp2S01_0757	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Vp2S01_0758	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Vp2S01_0759	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Vp2S01_0760	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Vp2S01_0761	ENOG4105C0B	DNA polymerase III (alpha subunit)
Vp2S01_0762	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Vp2S01_0763	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Vp2S01_0765	ENOG4108YZA	Nitrogen regulatory protein pii
Vp2S01_0766	ENOG4107NA1	Endonuclease Exonuclease phosphatase
Vp2S01_0768	ENOG4105E9H	Lytic Murein transglycosylase
Vp2S01_0769	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Vp2S01_0770	ENOG4105D1A	Methyltransferase
Vp2S01_0771	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Vp2S01_0772	ENOG4107RZZ	dna polymerase iii epsilon subunit
Vp2S01_0775	ENOG4107QPN	acyl-Coa dehydrogenase
Vp2S01_0776	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Vp2S01_0777	ENOG4105E7A	Glutamine amidotransferase
Vp2S01_0778	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Vp2S01_0779	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Vp2S01_0780	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Vp2S01_0781	ENOG4105C2W	permease
Vp2S01_0784	ENOG4105CS1	NAD(P)H quinone oxidoreductase
Vp2S01_0785	ENOG4105K89	arsenate reductase
Vp2S01_0786	ENOG4105ERG	peptidase m48, ste24p
Vp2S01_0789	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Vp2S01_0790	ENOG4105RH4	Glycine cleavage system transcriptional repressor
Vp2S01_0792	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
Vp2S01_0795	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Vp2S01_0796	ENOG4105KUZ	arsenate reductase
Vp2S01_0801	ENOG4105QZU	Inner membrane protein YfeZ
Vp2S01_0802	ENOG4105EZR	dyp-type peroxidase family protein
Vp2S01_0803	ENOG4105I03	Flagellin
Vp2S01_0804	ENOG4105I03	Flagellin
Vp2S01_0806	ENOG4105I03	Flagellin
Vp2S01_0807	ENOG41063QE	flagellar protein FlaG
Vp2S01_0808	ENOG4107BRV	flagellar capping protein
Vp2S01_0810	ENOG4105MQ3	flagellar protein FliS
Vp2S01_0811	ENOG4108JUA	Transcriptional regulator
Vp2S01_0812	ENOG4105BZU	Histidine kinase
Vp2S01_0813	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_0814	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
Vp2S01_0815	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
Vp2S01_0816	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Vp2S01_0818	ENOG4108JIR	Flagellum-specific ATP synthase
Vp2S01_0822	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Vp2S01_0823	ENOG4105DD5	Flagellar motor switch protein
Vp2S01_0824	ENOG4105VTB	flagellar biosynthesis protein fliO
Vp2S01_0825	ENOG4105CN7	Flagellar biosynthetic protein FliP
Vp2S01_0826	ENOG4105VS8	Flagellar biosynthetic protein fliq
Vp2S01_0827	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Vp2S01_0828	ENOG4105D00	flagellar biosynthetic protein flhB
Vp2S01_0829	ENOG4105D7B	Flagellar biosynthesis protein flha
Vp2S01_0830	ENOG4105FZW	flagellar biosynthesis regulator FlhF
Vp2S01_0831	ENOG4107R21	site-determining protein
Vp2S01_0832	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Vp2S01_0833	ENOG4108VYJ	response regulator receiver protein
Vp2S01_0834	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
Vp2S01_0835	ENOG4105CBS	Chea signal transduction histidine kinase
Vp2S01_0836	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Vp2S01_0837	ENOG4107QJE	Chromosome Partitioning Protein
Vp2S01_0839	ENOG4108V3W	Chemotaxis protein, CheW
Vp2S01_0841	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_0842	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
Vp2S01_0843	ENOG41060IM	Heme exporter protein
Vp2S01_0844	ENOG4105X3C	heme exporter protein
Vp2S01_0845	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
Vp2S01_0846	ENOG4105DA4	cytochrome c-type biogenesis protein
Vp2S01_0847	ENOG4107QX9	Thiol disulfide interChange protein
Vp2S01_0848	ENOG4108M1T	Cytochrome c-type biogenesis protein
Vp2S01_0850	ENOG410903C	(LipO)protein
Vp2S01_0851	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
Vp2S01_0852	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
Vp2S01_0855	ENOG4105CHU	acetyl-coa acetyltransferase
Vp2S01_0856	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Vp2S01_0858	ENOG4107QXK	peptidase
Vp2S01_0859	ENOG4108BY2	phosphohistidine phosphatase
Vp2S01_0860	ENOG4108DG9	Smr protein MutS2
Vp2S01_0861	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
Vp2S01_0862	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Vp2S01_0863	ENOG4105EN6	Membrane
Vp2S01_0865	ENOG4108BPE	-transporting atpase
Vp2S01_0866	ENOG4105MH2	YfcL protein
Vp2S01_0867	ENOG4105Q8W	reductase
Vp2S01_0868	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
Vp2S01_0869	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Vp2S01_0870	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
Vp2S01_0871	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Vp2S01_0873	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Vp2S01_0874	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Vp2S01_0875	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Vp2S01_0876	ENOG4108S3P	Sporulation domain protein
Vp2S01_0877	ENOG4105E96	Colicin v production protein
Vp2S01_0878	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
Vp2S01_0879	ENOG4105EJC	lysr family transcriptional regulator
Vp2S01_0880	ENOG4105I93	response regulator
Vp2S01_0882	ENOG4105WD1	Membrane
Vp2S01_0883	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Vp2S01_0884	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Vp2S01_0885	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Vp2S01_0886	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Vp2S01_0887	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Vp2S01_0888	ENOG4105C44	Serine transporter
Vp2S01_0889	ENOG4105KME	endoribonuclease L-psp
Vp2S01_0890	ENOG4105CEM	UPF0597 protein
Vp2S01_0892	ENOG4105KRS	Proteinase inhibitor
Vp2S01_0893	ENOG4105Y3U	Transglycosylase-associated protein
Vp2S01_0894	ENOG4108ZZ3	UPF0260 protein
Vp2S01_0896	ENOG41067V3	Antibiotic biosynthesis monooxygenase
Vp2S01_0897	ENOG4108UYE	Lactoylglutathione lyase
Vp2S01_0899	ENOG4105G6Z	alkaline phosphatase
Vp2S01_0902	ENOG4105DHI	Methyltransferase
Vp2S01_0903	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_0904	ENOG4105DSB	aldose 1-epimerase
Vp2S01_0905	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Vp2S01_0906	ENOG4105E0X	reductase
Vp2S01_0908	ENOG4105VUT	cytoplasmic protein
Vp2S01_0909	ENOG4105HDK	L-asparaginase
Vp2S01_0910	ENOG4105D07	Signal peptide peptidase, SppA
Vp2S01_0911	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Vp2S01_0912	ENOG41069NU	Nitroreductase
Vp2S01_0913	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Vp2S01_0915	ENOG4108RU0	short-chain dehydrogenase reductase
Vp2S01_0917	ENOG4105DGU	Histone deacetylase
Vp2S01_0925	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Vp2S01_0927	ENOG4105E68	Sulfatase
Vp2S01_0928	ENOG4105YDX	UPF0352 protein
Vp2S01_0929	ENOG4106V8H	Nucleoid-associated protein
Vp2S01_0932	ENOG4105DFD	Na H antiporter
Vp2S01_0933	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Vp2S01_0934	ENOG4105EYW	Ion transport protein
Vp2S01_0935	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
Vp2S01_0936	ENOG4108EKI	Dehydrogenase
Vp2S01_0939	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Vp2S01_0940	ENOG4105M2J	Glutaredoxin
Vp2S01_0942	ENOG4105D3Y	Na H antiporter
Vp2S01_0943	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
Vp2S01_0944	ENOG4105EIY	sodium-type flagellar protein motY
Vp2S01_0945	ENOG4106WH9	Protein of unknown function (DUF2753)
Vp2S01_0946	ENOG4108UYE	Lactoylglutathione lyase
Vp2S01_0947	ENOG4105CSM	endonuclease III
Vp2S01_0948	ENOG4105DZB	Electron transport complex
Vp2S01_0949	ENOG4108UQQ	Electron transport complex
Vp2S01_0950	ENOG4105D6A	Electron transport complex
Vp2S01_0952	ENOG4108R3D	Electron transport complex
Vp2S01_0953	ENOG4105DGN	Electron transport complex
Vp2S01_0954	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Vp2S01_0955	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_0957	ENOG4105CHW	UPF0052 protein
Vp2S01_0958	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Vp2S01_0959	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Vp2S01_0960	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Vp2S01_0961	ENOG4105M00	molybdopterin converting factor, subunit 1
Vp2S01_0962	ENOG4108ZAF	Molybdopterin
Vp2S01_0964	ENOG4107QSI	ABC, transporter
Vp2S01_0965	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Vp2S01_0966	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Vp2S01_0967	ENOG4105C3U	ABC transporter
Vp2S01_0968	ENOG4108JQ7	(ABC) transporter
Vp2S01_0969	ENOG4105CHF	Glutathione S-transferase
Vp2S01_0971	ENOG4107PU6	Membrane
Vp2S01_0972	ENOG4108DNC	Involved in acetate metabolism (By similarity)
Vp2S01_0973	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Vp2S01_0974	ENOG4105PQ6	UPF0208 membrane protein
Vp2S01_0976	ENOG4105C7J	ABC transporter, permease
Vp2S01_0977	ENOG4108JJB	ABC transporter
Vp2S01_0978	ENOG4107R28	alpha amylase, catalytic region
Vp2S01_0979	ENOG4105BZU	Histidine kinase
Vp2S01_0980	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
Vp2S01_0981	ENOG4106RHG	Yeca family
Vp2S01_0982	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
Vp2S01_0984	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Vp2S01_0985	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
Vp2S01_0987	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Vp2S01_0988	ENOG4105D1F	ATP-binding protein
Vp2S01_0989	ENOG4105DBI	uridine monophosphokinase
Vp2S01_0991	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
Vp2S01_0993	ENOG4105CHH	sulfate transporter
Vp2S01_0994	ENOG4105C03	ribonuclease
Vp2S01_0996	ENOG4105EI2	Pseudouridine synthase
Vp2S01_0997	ENOG4108UHJ	MAF-like protein
Vp2S01_0998	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
Vp2S01_0999	ENOG4105VGS	50s ribosomal protein l32
Vp2S01_1000	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Vp2S01_1001	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Vp2S01_1002	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Vp2S01_1003	ENOG4105CHR	reductase
Vp2S01_1004	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Vp2S01_1005	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Vp2S01_1007	ENOG4105HHA	aminodeoxychorismate lyase
Vp2S01_1008	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Vp2S01_1009	ENOG4107QRG	dna polymerase iii
Vp2S01_1010	ENOG4105F8V	Hydrolase, tatD family
Vp2S01_1011	ENOG4105CI1	PTS System
Vp2S01_1013	ENOG4105C8J	)-transporter
Vp2S01_1015	ENOG4108NRW	Phospholipase, patatin family
Vp2S01_1016	ENOG4105CA9	Pyruvate kinase
Vp2S01_1017	ENOG4105DAG	ROK family
Vp2S01_1018	ENOG4107R88	Chemotaxis protein (CheV)
Vp2S01_1019	ENOG4105C0B	DNA polymerase III (alpha subunit)
Vp2S01_1022	ENOG4105UBK	short-chain dehydrogenase reductase
Vp2S01_1023	ENOG4105ERU	peptidase
Vp2S01_1024	ENOG4105CAT	Cytidine monophosphate kinase
Vp2S01_1025	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Vp2S01_1026	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Vp2S01_1027	ENOG4105Q4A	inner membrane protein yciS
Vp2S01_1028	ENOG4105CFV	Tetratricopeptide repeat protein
Vp2S01_1029	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
Vp2S01_1030	ENOG4108J59	Extracellular solute-binding protein, family 5
Vp2S01_1033	ENOG4105CKK	Glycosyl transferase, family 2
Vp2S01_1035	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
Vp2S01_1037	ENOG4105DY2	Paraquat-inducible protein b
Vp2S01_1038	ENOG4105F1S	paraquat-inducible protein a
Vp2S01_1039	ENOG4105NQN	cytochrome C
Vp2S01_1041	ENOG4105DB1	molybdopterin oxidoreductase
Vp2S01_1042	ENOG4106WHD	Tetrathionate reductase
Vp2S01_1043	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Vp2S01_1044	ENOG4106AFQ	Histidine kinase
Vp2S01_1045	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Vp2S01_1046	ENOG4105EXG	Transcriptional regulator
Vp2S01_1048	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
Vp2S01_1053	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
Vp2S01_1055	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Vp2S01_1057	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Vp2S01_1058	ENOG4108W2Y	isochorismatase
Vp2S01_1059	ENOG41063TF	transcriptional regulator (AraC
Vp2S01_1061	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Vp2S01_1063	ENOG4105J12	Multidrug resistance protein mdtN
Vp2S01_1064	ENOG4105JQN	Transcriptional regulator
Vp2S01_1069	ENOG41062D9	Histidine kinase
Vp2S01_1070	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Vp2S01_1071	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_1072	ENOG4105CCT	upf0313 protein
Vp2S01_1076	ENOG4105DZ2	Transcriptional regulator
Vp2S01_1077	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Vp2S01_1079	ENOG4105K9H	YciI-like protein
Vp2S01_1080	ENOG4105NAU	thioesterase Superfamily protein
Vp2S01_1081	ENOG4107835	probably involved in intracellular septation (By similarity)
Vp2S01_1083	ENOG4105BZU	Histidine kinase
Vp2S01_1085	ENOG4105CK2	sodium dicarboxylate symporter
Vp2S01_1086	ENOG4105CEY	Amp-dependent synthetase and ligase
Vp2S01_1087	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Vp2S01_1088	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Vp2S01_1089	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Vp2S01_1090	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Vp2S01_1091	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Vp2S01_1092	ENOG4105DDQ	anthranilate synthase
Vp2S01_1093	ENOG4105CRQ	synthase (Component I)
Vp2S01_1095	ENOG4105DB7	PHP domain protein
Vp2S01_1096	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
Vp2S01_1098	ENOG4105FE9	pseudouridine synthase
Vp2S01_1099	ENOG4108W5H	UPF0263 protein
Vp2S01_1100	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Vp2S01_1102	ENOG4105CQ2	DNA polymerase
Vp2S01_1103	ENOG4105WH1	Two component transcriptional regulator luxr family
Vp2S01_1104	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Vp2S01_1109	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
Vp2S01_1114	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Vp2S01_1115	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Vp2S01_1116	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Vp2S01_1117	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Vp2S01_1120	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
Vp2S01_1122	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Vp2S01_1123	ENOG4105DVI	reductase, NrfD
Vp2S01_1124	ENOG4105DA4	cytochrome c-type biogenesis protein
Vp2S01_1125	ENOG4107QX9	Thiol disulfide interChange protein
Vp2S01_1126	ENOG4108DMF	Cytochrome C biogenesis protein
Vp2S01_1128	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
Vp2S01_1133	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
Vp2S01_1134	ENOG4105EAQ	(twin-arginine translocation) pathway signal
Vp2S01_1135	ENOG4105C5X	domain protein
Vp2S01_1138	ENOG4105CH5	extracellular solute-binding protein, family 7
Vp2S01_1140	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Vp2S01_1143	ENOG41067TZ	transcriptional regulator, MarR family
Vp2S01_1144	ENOG4105C94	Transporter
Vp2S01_1145	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_1149	ENOG4105CGF	Aromatic amino acid aminotransferase
Vp2S01_1152	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Vp2S01_1154	ENOG4105C5S	asparaginyl-tRNA synthetase
Vp2S01_1155	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_1157	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Vp2S01_1159	ENOG4105BZU	Histidine kinase
Vp2S01_1160	ENOG4105EJQ	L-serine dehydratase
Vp2S01_1161	ENOG4105C44	Serine transporter
Vp2S01_1162	ENOG4105P8F	nudix hydrolase
Vp2S01_1164	ENOG4105BZU	Histidine kinase
Vp2S01_1165	ENOG4105CRQ	synthase (Component I)
Vp2S01_1168	ENOG4105CM6	amino acid regulated cytosolic protein
Vp2S01_1169	ENOG4106K28	UPF0283 membrane protein
Vp2S01_1171	ENOG4105D9U	N-acetyltransferase
Vp2S01_1195	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Vp2S01_1204	ENOG410829K	Lysine exporter protein (Lyse ygga)
Vp2S01_1269	ENOG4105D3W	isochorismatase
Vp2S01_1275	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Vp2S01_1291	ENOG4105N14	lysine exporter protein LysE YggA
Vp2S01_1327	ENOG4105EWC	Purine nucleoside phosphorylase
Vp2S01_1336	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
Vp2S01_1337	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
Vp2S01_1370	ENOG4108J1Q	
Vp2S01_1376	ENOG4107S6Z	Na H antiporter
Vp2S01_1377	ENOG4105CFQ	glutamine synthetase
Vp2S01_1378	ENOG4108Z86	Glutamine amidotransferase
Vp2S01_1379	ENOG4107VRI	Transcriptional regulator
Vp2S01_1380	ENOG4105C26	Dehydrogenase
Vp2S01_1381	ENOG4105CJP	fad dependent oxidoreductase
Vp2S01_1383	ENOG4105DWY	Agmatine deiminase
Vp2S01_1384	ENOG4105C26	Dehydrogenase
Vp2S01_1385	ENOG4108JPW	Aminotransferase
Vp2S01_1386	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Vp2S01_1387	ENOG4105BZU	Histidine kinase
Vp2S01_1390	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Vp2S01_1393	ENOG4108ZT1	Transcriptional regulator
Vp2S01_1394	ENOG4105MSB	protein, conserved in bacteria
Vp2S01_1398	ENOG4108UW5	maltose o-acetyltransferase
Vp2S01_1401	ENOG4105BZU	Histidine kinase
Vp2S01_1402	ENOG4105BZU	Histidine kinase
Vp2S01_1405	ENOG41090FY	type IV pilus biogenesis stability protein PilW
Vp2S01_1406	ENOG4105CVG	Homoserine O-transsuccinylase
Vp2S01_1408	ENOG4105E5D	amino acid
Vp2S01_1410	ENOG4105D1S	lipid A biosynthesis
Vp2S01_1411	ENOG4105CTD	carboxy-peptidase
Vp2S01_1412	ENOG410829K	Lysine exporter protein (Lyse ygga)
Vp2S01_1414	ENOG4105BZG	amino acid carrier protein
Vp2S01_1419	ENOG4105E0M	Sulfatase
Vp2S01_1420	ENOG4105DHQ	Histidine kinase
Vp2S01_1427	ENOG4105GIJ	Glycine betaine
Vp2S01_1428	ENOG4108HQS	Glycine betaine
Vp2S01_1429	ENOG4108IJ7	Glycine betaine
Vp2S01_1432	ENOG4105C94	Transporter
Vp2S01_1433	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
Vp2S01_1434	ENOG4108JPW	Aminotransferase
Vp2S01_1435	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
Vp2S01_1436	ENOG4105CZK	Aspartate kinase
Vp2S01_1439	ENOG4105CA0	peroxidase
Vp2S01_1442	ENOG4107V40	secretion protein, HlyD family
Vp2S01_1444	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
Vp2S01_1445	ENOG4108V9W	transcriptional regulatory protein
Vp2S01_1446	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
Vp2S01_1447	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
Vp2S01_1448	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
Vp2S01_1452	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
Vp2S01_1453	ENOG4105C26	Dehydrogenase
Vp2S01_1457	ENOG4108KB1	transcriptional regulator, arac family
Vp2S01_1463	ENOG41066XE	Type III export protein
Vp2S01_1477	ENOG4105ENX	hydrolase
Vp2S01_1478	ENOG4105ENX	hydrolase
Vp2S01_1479	ENOG4105EQ2	LysR family Transcriptional regulator
Vp2S01_1501	ENOG4105EJ9	Membrane
Vp2S01_1508	ENOG4105CR4	methylisocitrate lyase
Vp2S01_1509	ENOG4105BZN	citrate synthase
Vp2S01_1510	ENOG4108I0Z	Aconitate hydratase
Vp2S01_1511	ENOG4105C7F	AcnD-accessory protein PrpF
Vp2S01_1512	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Vp2S01_1514	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
Vp2S01_1516	ENOG410667J	hydrolase
Vp2S01_1517	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Vp2S01_1518	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Vp2S01_1519	ENOG4105BZU	Histidine kinase
Vp2S01_1521	ENOG4105CDV	Ompa motb domain protein
Vp2S01_1524	ENOG4105CDV	Ompa motb domain protein
Vp2S01_1527	ENOG4105DR4	Methyltransferase
Vp2S01_1529	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_1531	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Vp2S01_1532	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
Vp2S01_1534	ENOG4108MN8	Membrane
Vp2S01_1535	ENOG4105CDA	abc transporter atp-binding protein
Vp2S01_1536	ENOG4105DRP	amino acid AbC transporter
Vp2S01_1537	ENOG4105EZ7	amino acid ABC transporter
Vp2S01_1538	ENOG4107QXX	ABC transporter
Vp2S01_1540	ENOG4108VPT	UPF0234 protein
Vp2S01_1541	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Vp2S01_1545	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Vp2S01_1546	ENOG4105DY2	Paraquat-inducible protein b
Vp2S01_1547	ENOG4105H2K	paraquat-inducible protein a
Vp2S01_1548	ENOG4105BZ1	(ABC) transporter
Vp2S01_1549	ENOG4108ZGC	gaf domain protein
Vp2S01_1550	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
Vp2S01_1551	ENOG4105CN1	protease
Vp2S01_1553	ENOG4105CD8	aminopeptidase N
Vp2S01_1554	ENOG4105C7I	Dehydrogenase
Vp2S01_1555	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Vp2S01_1556	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
Vp2S01_1557	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Vp2S01_1559	ENOG4105C5H	ABC transporter
Vp2S01_1561	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
Vp2S01_1562	ENOG4105DAN	ATP-dependent protease
Vp2S01_1563	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
Vp2S01_1571	ENOG4105BZU	Histidine kinase
Vp2S01_1574	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
Vp2S01_1577	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
Vp2S01_1579	ENOG4105C59	p-type ATPase
Vp2S01_1582	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Vp2S01_1583	ENOG4105Q9Y	Universal stress protein
Vp2S01_1584	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Vp2S01_1588	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_1589	ENOG4105F38	ABC transporter, permease
Vp2S01_1590	ENOG4105D38	putrescine abc transporter
Vp2S01_1591	ENOG4107RUE	extracellular solute-binding protein family 1
Vp2S01_1592	ENOG4107RUE	extracellular solute-binding protein family 1
Vp2S01_1593	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Vp2S01_1601	ENOG4105QAX	Iron-sulfur
Vp2S01_1602	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Vp2S01_1604	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
Vp2S01_1608	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Vp2S01_1609	ENOG4105C5H	ABC transporter
Vp2S01_1610	ENOG4105BZU	Histidine kinase
Vp2S01_1611	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_1614	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_1615	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Vp2S01_1616	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Vp2S01_1618	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
Vp2S01_1619	ENOG4106IUH	DTW domain containing protein
Vp2S01_1626	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_1627	ENOG4107TT5	NLP P60 protein
Vp2S01_1629	ENOG4105BZU	Histidine kinase
Vp2S01_1630	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Vp2S01_1631	ENOG4105FGM	Fructosamine kinase
Vp2S01_1633	ENOG4108R6K	riboflavin synthase, subunit alpha
Vp2S01_1634	ENOG4107QI1	Mate efflux family protein
Vp2S01_1637	ENOG41082AN	stage II sporulation protein
Vp2S01_1639	ENOG4107V1M	polysaccharide export protein
Vp2S01_1642	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_1644	ENOG4107TYR	Glycosyl Transferase
Vp2S01_1650	ENOG4105CPK	Glycosyl transferase (Group 1
Vp2S01_1651	ENOG4105CND	Glycosyl transferase, family 2
Vp2S01_1654	ENOG4105C94	Transporter
Vp2S01_1657	ENOG4105CQ7	ATP-dependent helicase
Vp2S01_1658	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
Vp2S01_1660	ENOG4108NEM	leader-binding protein dmsD
Vp2S01_1661	ENOG4107KGK	dmso reductase anchor subunit
Vp2S01_1662	ENOG4105QAX	Iron-sulfur
Vp2S01_1663	ENOG4107QY8	reductase
Vp2S01_1671	ENOG4105CFG	Acts as a chaperone (By similarity)
Vp2S01_1672	ENOG4105CFG	Acts as a chaperone (By similarity)
Vp2S01_1677	ENOG4105BZ1	(ABC) transporter
Vp2S01_1678	ENOG4105BZ1	(ABC) transporter
Vp2S01_1682	ENOG4105E0U	tyrosine-specific transport protein
Vp2S01_1685	ENOG4105DHT	Metal Dependent Phosphohydrolase
Vp2S01_1709	ENOG4105D9P	serine threonine protein kinase
Vp2S01_1714	ENOG4105CS6	Rhs element vgr protein
Vp2S01_1715	ENOG4108WC9	type VI secretion system effector, hcp1 family
Vp2S01_1716	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Vp2S01_1717	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_1722	ENOG4105DR5	peptidase
Vp2S01_1723	ENOG4105EE5	Membrane protein terC
Vp2S01_1725	ENOG41076CZ	activating enzyme
Vp2S01_1726	ENOG4105G0K	glycine radical enzyme YjjI family
Vp2S01_1728	ENOG4105CPI	Metal Dependent Phosphohydrolase
Vp2S01_1729	ENOG4105BZU	Histidine kinase
Vp2S01_1730	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_1731	ENOG4105BZU	Histidine kinase
Vp2S01_1732	ENOG4105C8P	)-transporter
Vp2S01_1740	ENOG4105DUM	transcriptional regulator, lysR family
Vp2S01_1744	ENOG4105Y49	secretion protein, HlyD family
Vp2S01_1756	ENOG4105C79	DNA protecting protein DprA
Vp2S01_1783	ENOG4108N0N	Phage Terminase Large Subunit
Vp2S01_1815	ENOG4108RXX	maleylacetoacetate isomerase
Vp2S01_1817	ENOG4105F1J	Homogentisate 1,2-dioxygenase
Vp2S01_1818	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
Vp2S01_1819	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Vp2S01_1820	ENOG4107QSI	ABC, transporter
Vp2S01_1821	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Vp2S01_1822	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Vp2S01_1823	ENOG4105C3U	ABC transporter
Vp2S01_1824	ENOG4108JQ7	(ABC) transporter
Vp2S01_1826	ENOG4107MM9	BNR Asp-box repeat-containing protein
Vp2S01_1829	ENOG4105D38	putrescine abc transporter
Vp2S01_1830	ENOG4105F38	ABC transporter, permease
Vp2S01_1831	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_1832	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Vp2S01_1833	ENOG4105CIF	Ornithine Cyclodeaminase
Vp2S01_1836	ENOG4105CTU	Proline racemase
Vp2S01_1842	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
Vp2S01_1843	ENOG4108VKG	metal-dependent hydrolase
Vp2S01_1845	ENOG4107RSM	transcriptional regulator
Vp2S01_1849	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_1850	ENOG4108IU2	vtamin B12-transporter permease
Vp2S01_1851	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
Vp2S01_1856	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
Vp2S01_1857	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
Vp2S01_1859	ENOG4105K4T	epimerase
Vp2S01_1860	ENOG4108ETY	sodium dicarboxylate symporter
Vp2S01_1861	ENOG4105CJB	Exodeoxyribonuclease I
Vp2S01_1862	ENOG4105VAW	lrga family
Vp2S01_1863	ENOG41067MG	lrgb family
Vp2S01_1864	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
Vp2S01_1865	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
Vp2S01_1866	ENOG4105FQ6	thiopurine methyltransferase
Vp2S01_1868	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Vp2S01_1870	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Vp2S01_1871	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Vp2S01_1872	ENOG4105BZU	Histidine kinase
Vp2S01_1878	ENOG4105K8R	UPF0145 protein
Vp2S01_1879	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Vp2S01_1880	ENOG41082NX	50s ribosomal protein l35
Vp2S01_1881	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Vp2S01_1882	ENOG4105C22	threonyL-tRNA synthetase
Vp2S01_1885	ENOG4105CZE	histidine utilization repressor
Vp2S01_1886	ENOG4105CI2	imidazolone-5-propionate hydrolase
Vp2S01_1887	ENOG41088SP	formiminoglutamate hydrolase
Vp2S01_1889	ENOG4105C84	Histidine ammonia-lyase
Vp2S01_1892	ENOG4105CQB	FAD linked oxidase domain protein
Vp2S01_1895	ENOG4105CDV	Ompa motb domain protein
Vp2S01_1899	ENOG4105C8V	SAICAR synthetase
Vp2S01_1902	ENOG4105HDD	phospholipase
Vp2S01_1903	ENOG4105CQ7	ATP-dependent helicase
Vp2S01_1904	ENOG4107R1I	NAD-dependent malic enzyme
Vp2S01_1906	ENOG4107GZ4	SanA protein
Vp2S01_1907	ENOG4105C8P	)-transporter
Vp2S01_1908	ENOG4105BZU	Histidine kinase
Vp2S01_1913	ENOG4105C3M	thioredoxin reductase
Vp2S01_1914	ENOG4108JJ9	ABC, transporter
Vp2S01_1915	ENOG4108JJ8	(ABC) transporter
Vp2S01_1916	ENOG4105BZC	d-serine deaminase
Vp2S01_1917	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Vp2S01_1919	ENOG4105BZU	Histidine kinase
Vp2S01_1925	ENOG4105DWU	Membrane
Vp2S01_1927	ENOG4105DY8	decarboxylase
Vp2S01_1928	ENOG4106KNT	transcriptional regulator
Vp2S01_1930	ENOG41090BQ	Glutaredoxin
Vp2S01_1931	ENOG4105D0C	transport protein
Vp2S01_1932	ENOG4105RKW	reductase (By
Vp2S01_1933	ENOG4107QPN	acyl-Coa dehydrogenase
Vp2S01_1934	ENOG41067SE	Tetr family transcriptional regulator
Vp2S01_1935	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Vp2S01_1938	ENOG4108I0Y	(ABC) transporter
Vp2S01_1939	ENOG4107QI1	Mate efflux family protein
Vp2S01_1940	ENOG4105CGD	Nad-dependent epimerase dehydratase
Vp2S01_1941	ENOG4105CUW	cytochrome C-TYPE protein
Vp2S01_1947	ENOG4105C2C	drug resistance transporter, Bcr CflA
Vp2S01_1948	ENOG4105I08	Pseudouridine synthase
Vp2S01_1949	ENOG4105CFI	type iii restriction protein res subunit
Vp2S01_1951	ENOG4105ETX	regulatoR
Vp2S01_1952	ENOG4105EB3	Histidine kinase
Vp2S01_1953	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Vp2S01_1956	ENOG4105CGH	5'-nucleotidase
Vp2S01_1959	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Vp2S01_1960	ENOG4106AFQ	Histidine kinase
Vp2S01_1962	ENOG4105BZ8	glutamate synthase
Vp2S01_1964	ENOG4108RSN	SNARE associated Golgi
Vp2S01_1965	ENOG4105VNH	ABC transporter solute-binding protein
Vp2S01_1966	ENOG4105CXZ	ABC transporter, permease
Vp2S01_1967	ENOG4108VGW	abc transporter atp-binding protein
Vp2S01_1968	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
Vp2S01_1970	ENOG4108JUA	Transcriptional regulator
Vp2S01_1971	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
Vp2S01_1972	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
Vp2S01_1974	ENOG4108W1A	pseudouridine synthase
Vp2S01_1976	ENOG4105C8J	)-transporter
Vp2S01_1978	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Vp2S01_1979	ENOG4105C28	cystathionine
Vp2S01_1980	ENOG4107IFA	Lipase (EC 3.1.1.3)
Vp2S01_1982	ENOG4108R3E	Dna-3-methyladenine glycosylase i
Vp2S01_1985	ENOG410624X	efflux transporter, rnd family, mfp subunit
Vp2S01_1986	ENOG4105FM1	phage shock protein C
Vp2S01_1987	ENOG4105YYT	phage shock protein B
Vp2S01_1988	ENOG41087YS	Phage shock protein A
Vp2S01_1989	ENOG4105E51	psp operon transcriptional activator
Vp2S01_1990	ENOG4108J59	Extracellular solute-binding protein, family 5
Vp2S01_1991	ENOG4108I5W	peptide transport system, permease protein
Vp2S01_1992	ENOG4108EU3	peptide transport system, permease
Vp2S01_1993	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
Vp2S01_1994	ENOG4108JQ2	peptide transport system atp-binding protein
Vp2S01_1996	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Vp2S01_1999	ENOG4108J2R	molybdopterin oxidoreductase
Vp2S01_2003	ENOG4105C4B	ABC transporter, permease
Vp2S01_2005	ENOG4105TMB	Formate nitrite transporter
Vp2S01_2010	ENOG4105GFG	DUF218 domain
Vp2S01_2011	ENOG4107104	thymidine kinase
Vp2S01_2012	ENOG4105C8N	cysteinyl-tRNA synthetase
Vp2S01_2013	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Vp2S01_2014	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
Vp2S01_2015	ENOG4105D58	Diguanylate phosphodiesterase
Vp2S01_2016	ENOG4105K5B	UPF0225 protein
Vp2S01_2017	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Vp2S01_2018	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Vp2S01_2020	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Vp2S01_2021	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Vp2S01_2022	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Vp2S01_2023	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Vp2S01_2024	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Vp2S01_2025	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_2027	ENOG4107S6Z	Na H antiporter
Vp2S01_2028	ENOG4108YX2	DNA-binding protein
Vp2S01_2029	ENOG4107RE1	Inosine-guanosine kinase
Vp2S01_2031	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Vp2S01_2032	ENOG41075W9	High frequency lysogenization protein HflD homolog
Vp2S01_2033	ENOG4107QTF	adenylosuccinate lyase
Vp2S01_2037	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Vp2S01_2040	ENOG4107FW0	short-chain dehydrogenase reductase
Vp2S01_2042	ENOG4105D0M	Protease HtpX homolog
Vp2S01_2044	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
Vp2S01_2046	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Vp2S01_2047	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Vp2S01_2048	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Vp2S01_2049	ENOG4105KSC	Transcriptional regulator, TraR DksA family
Vp2S01_2052	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Vp2S01_2053	ENOG4105D1H	recombination factor protein RarA
Vp2S01_2054	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
Vp2S01_2055	ENOG4105CNU	cell division protein FtsK
Vp2S01_2056	ENOG4105EW9	transcriptional regulator AsnC family
Vp2S01_2057	ENOG4105DCF	alanine dehydrogenase
Vp2S01_2059	ENOG4107R11	Transcriptional regulator
Vp2S01_2061	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
Vp2S01_2068	ENOG4105BZS	acriflavin resistance protein
Vp2S01_2069	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Vp2S01_2070	ENOG4108N3W	hemolysin secretion protein
Vp2S01_2081	ENOG4108RNS	Exports L-alanine (By similarity)
Vp2S01_2082	ENOG4105BZU	Histidine kinase
Vp2S01_2084	ENOG4106032	Glutathionylspermidine synthase
Vp2S01_2086	ENOG4105Z6B	inner membrane protein yjfl
Vp2S01_2088	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Vp2S01_2089	ENOG4105UFD	tol-pal system protein YbgF
Vp2S01_2090	ENOG4105KCK	Peptidoglycan-associated lipoprotein
Vp2S01_2091	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
Vp2S01_2093	ENOG4105M8F	Biopolymer transport protein exbD tolR
Vp2S01_2094	ENOG4105E02	MotA TolQ exbB proton channel
Vp2S01_2095	ENOG4107YD3	Thioesterase
Vp2S01_2097	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Vp2S01_2098	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Vp2S01_2099	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Vp2S01_2100	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Vp2S01_2101	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_2102	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Vp2S01_2103	ENOG4105C9M	aspartyl-trna synthetase
Vp2S01_2104	ENOG41081XQ	Conserved Protein
Vp2S01_2105	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
Vp2S01_2106	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
Vp2S01_2107	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Vp2S01_2109	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Vp2S01_2111	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
Vp2S01_2112	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
Vp2S01_2113	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
Vp2S01_2114	ENOG4106371	Methyltransferase
Vp2S01_2115	ENOG4107S90	membrAne
Vp2S01_2116	ENOG4106WF9	DNA-binding transcriptional regulator TorR
Vp2S01_2117	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
Vp2S01_2118	ENOG4105ETE	Transcriptional regulator (LacI family
Vp2S01_2119	ENOG4105HP8	regulator of competence-specific genes
Vp2S01_2123	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Vp2S01_2124	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Vp2S01_2125	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Vp2S01_2126	ENOG4105RKX	Protein of unknown function (DUF2498)
Vp2S01_2127	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Vp2S01_2129	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
Vp2S01_2130	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
Vp2S01_2131	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Vp2S01_2133	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Vp2S01_2134	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Vp2S01_2135	ENOG4105VEQ	Cold shock protein
Vp2S01_2137	ENOG4108R99	pseudouridine synthase
Vp2S01_2140	ENOG4105DVT	helicase
Vp2S01_2141	ENOG4105EJ9	Membrane
Vp2S01_2142	ENOG4108URS	primosomal replication protein n''
Vp2S01_2143	ENOG4106428	Protein of unknown function (DUF2496)
Vp2S01_2144	ENOG4105CGK	Exodeoxyribonuclease III
Vp2S01_2147	ENOG4105DSP	amino acid AbC transporter
Vp2S01_2148	ENOG4105E89	ABC transporter
Vp2S01_2149	ENOG4108JEH	abc transporter atp-binding protein
Vp2S01_2152	ENOG4105C6N	Formate acetyltransferase
Vp2S01_2154	ENOG4105F1A	Pyruvate formate-lyase
Vp2S01_2156	ENOG4105XWI	UPF0304 protein
Vp2S01_2157	ENOG4105CYN	Serine protein kinase
Vp2S01_2158	ENOG4106AKX	UPF0229 protein
Vp2S01_2159	ENOG4105ED1	spovr family
Vp2S01_2160	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Vp2S01_2161	ENOG4105W49	UPF0434 protein
Vp2S01_2162	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Vp2S01_2163	ENOG4105BZ1	(ABC) transporter
Vp2S01_2164	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
Vp2S01_2166	ENOG4105D60	lipoprotein releasing system transmembrane protein
Vp2S01_2167	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Vp2S01_2168	ENOG4105D60	lipoprotein releasing system transmembrane protein
Vp2S01_2170	ENOG4108JA2	transcriptioN-repair coupling factor
Vp2S01_2173	ENOG4105CEP	NADH dehydrogenase
Vp2S01_2174	ENOG4105D0Y	UPF0227 protein
Vp2S01_2179	ENOG4105K59	histidine triad (HIT) protein
Vp2S01_2180	ENOG4108NVR	Methyl-accepting chemotaxis
Vp2S01_2182	ENOG4107SXA	Phosphorylase
Vp2S01_2184	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Vp2S01_2185	ENOG4105DZ0	fad dependent oxidoreductase
Vp2S01_2186	ENOG4108Z4U	Ferredoxin
Vp2S01_2205	ENOG4108KHX	Diguanylate cyclase
Vp2S01_2209	ENOG4108MNP	Glycoprotein polysaccharide metabolism
Vp2S01_2210	ENOG4105C29	acyl-CoA thioesterase
Vp2S01_2212	ENOG4108XM1	transcriptional regulator AsnC family
Vp2S01_2217	ENOG4105BZS	acriflavin resistance protein
Vp2S01_2221	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
Vp2S01_2222	ENOG4105HMI	Membrane
Vp2S01_2224	ENOG4105CEY	Amp-dependent synthetase and ligase
Vp2S01_2225	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
Vp2S01_2226	ENOG4108IPT	Naphthoate synthase
Vp2S01_2227	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
Vp2S01_2228	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
Vp2S01_2229	ENOG4105E4F	Isochorismate synthase
Vp2S01_2230	ENOG4105CHM	Aminotransferase
Vp2S01_2231	ENOG4105DK2	UPF0207 protein
Vp2S01_2232	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Vp2S01_2235	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
Vp2S01_2236	ENOG4105EIN	peptidylprolyl cis-trans isomerase
Vp2S01_2237	ENOG4105K70	DNA-binding protein
Vp2S01_2238	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Vp2S01_2239	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Vp2S01_2240	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Vp2S01_2241	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Vp2S01_2242	ENOG4105CQZ	Histidine kinase
Vp2S01_2244	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Vp2S01_2245	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
Vp2S01_2246	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Vp2S01_2247	ENOG4105CNG	UPF0061 protein
Vp2S01_2252	ENOG4107ZYR	domain protein
Vp2S01_2253	ENOG4105C1J	atp-dependent rna helicase
Vp2S01_2261	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Vp2S01_2265	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Vp2S01_2266	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
Vp2S01_2267	ENOG4105C84	Histidine ammonia-lyase
Vp2S01_2272	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Vp2S01_2273	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Vp2S01_2274	ENOG4105C2D	reductase
Vp2S01_2275	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Vp2S01_2278	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Vp2S01_2279	ENOG4105D9N	nucleoside
Vp2S01_2280	ENOG4105CC0	LysR family Transcriptional regulator
Vp2S01_2281	ENOG4105CVE	Lytic murein transglycosylase
Vp2S01_2282	ENOG4105VNG	YcgL domain-containing protein
Vp2S01_2283	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Vp2S01_2284	ENOG4107QMS	site-determining protein
Vp2S01_2285	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Vp2S01_2286	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
Vp2S01_2287	ENOG4105CEY	Amp-dependent synthetase and ligase
Vp2S01_2288	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
Vp2S01_2291	ENOG41072GX	Peptidase M22 Glycoprotease
Vp2S01_2292	ENOG4105DVT	helicase
Vp2S01_2293	ENOG4105CIY	formyltetrahydrofolate deformylase
Vp2S01_2294	ENOG4106ZCM	YecM protein
Vp2S01_2295	ENOG4105C75	arginyL-tRNA synthetase
Vp2S01_2298	ENOG4105CE1	Ferrous iron transport protein b
Vp2S01_2299	ENOG4105XFK	Ferrous iron transport protein A
Vp2S01_2301	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
Vp2S01_2302	ENOG4105NXV	High-affinity zinc uptake system protein
Vp2S01_2303	ENOG4105FDK	ABC transporter
Vp2S01_2304	ENOG4105FAV	ABC, transporter
Vp2S01_2305	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Vp2S01_2306	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Vp2S01_2307	ENOG4105C7S	Dehydrogenase
Vp2S01_2308	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Vp2S01_2309	ENOG4105E33	succinate dehydrogenase
Vp2S01_2310	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
Vp2S01_2311	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
Vp2S01_2312	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
Vp2S01_2313	ENOG4105BZN	citrate synthase
Vp2S01_2314	ENOG4107QNR	UPF0135 protein
Vp2S01_2316	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
Vp2S01_2317	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
Vp2S01_2318	ENOG4105EV9	Alpha Beta Hydrolase
Vp2S01_2320	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
Vp2S01_2321	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Vp2S01_2322	ENOG41090R7	Ferric uptake
Vp2S01_2323	ENOG4105CX6	glutaminyL-tRNA synthetase
Vp2S01_2325	ENOG4105CE4	GlcNAc 6-P deacetylase
Vp2S01_2326	ENOG4105E2R	ROK family
Vp2S01_2327	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Vp2S01_2328	ENOG4105CAQ	asparagine synthetase
Vp2S01_2329	ENOG4105MDZ	Transcriptional activator rfaH
Vp2S01_2330	ENOG4105DUX	Transporter
Vp2S01_2331	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Vp2S01_2332	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Vp2S01_2333	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
Vp2S01_2334	ENOG4108DQ1	activator toxR
Vp2S01_2338	ENOG4108RE9	Phosphodiesterase
Vp2S01_2343	ENOG4105ECP	epimerase
Vp2S01_2344	ENOG4105E1F	short-chain dehydrogenase reductase
Vp2S01_2345	ENOG4107QR8	Thioredoxin
Vp2S01_2346	ENOG4107QX8	SPFH domain, Band 7 family protein
Vp2S01_2349	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Vp2S01_2350	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
Vp2S01_2351	ENOG4105EXN	Sulfate transport protein CysZ
Vp2S01_2352	ENOG4105C6T	cysteine synthase
Vp2S01_2353	ENOG4105KZ7	phosphocarrier protein hpr
Vp2S01_2354	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Vp2S01_2355	ENOG4105C5Y	PTS System
Vp2S01_2357	ENOG4105I03	Flagellin
Vp2S01_2358	ENOG4105I03	Flagellin
Vp2S01_2360	ENOG4105DTJ	flagellar hook-associated protein
Vp2S01_2362	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
Vp2S01_2363	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Vp2S01_2364	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Vp2S01_2365	ENOG4105CGA	flagellar basal-body rod protein FlgG
Vp2S01_2366	ENOG4108KPB	Flagellar basal-body rod protein FlgF
Vp2S01_2368	ENOG4105BZE	flagellar hook protein, FlgE
Vp2S01_2369	ENOG4105W00	Flagellar hook capping protein
Vp2S01_2370	ENOG4108ZC9	flagellar basal-body rod protein flgc
Vp2S01_2371	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
Vp2S01_2372	ENOG4105BZU	Histidine kinase
Vp2S01_2373	ENOG4107R88	Chemotaxis protein (CheV)
Vp2S01_2382	ENOG4105UYK	outer membrane protein a
Vp2S01_2383	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Vp2S01_2385	ENOG41081QG	Porin Gram-negative type
Vp2S01_2387	ENOG4105C59	p-type ATPase
Vp2S01_2390	ENOG4105E2D	ec 3.2.1.52
Vp2S01_2393	ENOG4108DG9	Smr protein MutS2
Vp2S01_2394	ENOG4105FE9	pseudouridine synthase
Vp2S01_2395	ENOG4108Z66	YbaK ebsC protein
Vp2S01_2396	ENOG4105CGH	5'-nucleotidase
Vp2S01_2397	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Vp2S01_2398	ENOG41063JG	Transcriptional regulator
Vp2S01_2399	ENOG4108YY7	Invasion gene expression up-regulator SirB
Vp2S01_2400	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Vp2S01_2401	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Vp2S01_2402	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Vp2S01_2403	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
Vp2S01_2404	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Vp2S01_2405	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Vp2S01_2406	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Vp2S01_2407	ENOG4105C3G	gtp-binding protein
Vp2S01_2410	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
Vp2S01_2411	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Vp2S01_2412	ENOG4105C9A	Phoh family
Vp2S01_2413	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Vp2S01_2414	ENOG4108JU5	Magnesium and cobalt efflux protein
Vp2S01_2415	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Vp2S01_2416	ENOG4107PAI	alpha helical protein
Vp2S01_2417	ENOG4105C8T	Leucyl-tRNA synthetase
Vp2S01_2418	ENOG4108U2H	Rare lipoprotein B
Vp2S01_2419	ENOG4105DJF	DNA polymerase III, delta' subunit
Vp2S01_2420	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
Vp2S01_2421	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Vp2S01_2422	ENOG4105CJN	penicillin-binding protein
Vp2S01_2423	ENOG4105CNI	cell division protein FtsW
Vp2S01_2424	ENOG4105K6T	rare lipoprotein A
Vp2S01_2425	ENOG4105DZ1	carboxypeptidase
Vp2S01_2426	ENOG4108Z43	UPF0250 protein
Vp2S01_2427	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Vp2S01_2428	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Vp2S01_2429	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Vp2S01_2430	ENOG4108JYZ	YitT family
Vp2S01_2433	ENOG4105CG3	alpha amylase, catalytic region
Vp2S01_2434	ENOG4105C5Y	PTS System
Vp2S01_2435	ENOG4105D4X	repressor
Vp2S01_2436	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
Vp2S01_2438	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_2439	ENOG4108UMI	ABC transporter, permease
Vp2S01_2440	ENOG4105D01	(LipO)protein
Vp2S01_2441	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
Vp2S01_2442	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
Vp2S01_2443	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Vp2S01_2445	ENOG4105BZU	Histidine kinase
Vp2S01_2446	ENOG4105EWT	decarboxylase family
Vp2S01_2447	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
Vp2S01_2449	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
Vp2S01_2450	ENOG4105M08	Membrane
Vp2S01_2452	ENOG4105ETT	transcriptional Regulator, LysR family
Vp2S01_2453	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Vp2S01_2455	ENOG4107QKZ	Ompa motb domain protein
Vp2S01_2456	ENOG4105E14	MotA TolQ exbB proton channel
Vp2S01_2457	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Vp2S01_2458	ENOG4105CTB	Polyprenyl synthetase
Vp2S01_2459	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Vp2S01_2460	ENOG4108ZAI	phosphatidylglycerophosphatase a
Vp2S01_2461	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Vp2S01_2462	ENOG4107YIM	Involved in the transcription termination process (By similarity)
Vp2S01_2463	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Vp2S01_2466	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Vp2S01_2467	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Vp2S01_2468	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Vp2S01_2469	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Vp2S01_2470	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
Vp2S01_2471	ENOG4108DJV	Fermentation respiration switch protein
Vp2S01_2472	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
Vp2S01_2473	ENOG4105C7N	Xanthine uracil vitamin C permease
Vp2S01_2474	ENOG4105CIN	aminoacyl-histidine dipeptidase
Vp2S01_2479	ENOG4108ETH	Formylglycinamide ribotide synthetase
Vp2S01_2480	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
Vp2S01_2482	ENOG4108Z6B	deaminase
Vp2S01_2483	ENOG4105CFC	Transporter
Vp2S01_2490	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Vp2S01_2491	ENOG4105CFG	Acts as a chaperone (By similarity)
Vp2S01_2493	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Vp2S01_2494	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Vp2S01_2496	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Vp2S01_2497	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
Vp2S01_2498	ENOG4105VDB	UPF0125 protein
Vp2S01_2499	ENOG4108Z1B	Cyclase dehydrase
Vp2S01_2500	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Vp2S01_2501	ENOG4105DFP	Integrase
Vp2S01_2502	ENOG4105CVR	type I restriction-modification system
Vp2S01_2504	ENOG4105DZR	Type I site-specific deoxyribonuclease
Vp2S01_2507	ENOG4105CVR	type I restriction-modification system
Vp2S01_2510	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Vp2S01_2511	ENOG4108YGG	dna repair protein
Vp2S01_2520	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Vp2S01_2526	ENOG4105ETT	transcriptional Regulator, LysR family
Vp2S01_2527	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
Vp2S01_2531	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Vp2S01_2532	ENOG4108IQK	o-acetylhomoserine
Vp2S01_2538	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Vp2S01_2539	ENOG4105BZG	amino acid carrier protein
Vp2S01_2541	ENOG4106HK8	GPR1 FUN34 yaaH family protein
Vp2S01_2543	ENOG4107S6Z	Na H antiporter
Vp2S01_2544	ENOG4107S6Z	Na H antiporter
Vp2S01_2545	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Vp2S01_2546	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Vp2S01_2547	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Vp2S01_2550	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Vp2S01_2551	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
Vp2S01_2552	ENOG4105N21	Membrane
Vp2S01_2553	ENOG4105CUT	histidyl-tRNA synthetase
Vp2S01_2554	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Vp2S01_2556	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Vp2S01_2557	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Vp2S01_2558	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Vp2S01_2559	ENOG4105WVQ	Fe-S assembly protein IscX
Vp2S01_2560	ENOG4108ZIT	Ferredoxin, 2FE-2S
Vp2S01_2561	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
Vp2S01_2562	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
Vp2S01_2563	ENOG4108Z4V	iron-sulfur cluster assembly
Vp2S01_2564	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
Vp2S01_2565	ENOG4105C3J	Cysteine desulfurase
Vp2S01_2566	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Vp2S01_2567	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
Vp2S01_2568	ENOG4105ECY	inositol monophosphatase
Vp2S01_2569	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Vp2S01_2570	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Vp2S01_2571	ENOG4105VIE	preprotein translocase, subunit YajC
Vp2S01_2572	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Vp2S01_2573	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Vp2S01_2575	ENOG4105W87	Cbs domain
Vp2S01_2576	ENOG4108I9X	Isocitrate lyase
Vp2S01_2577	ENOG4107QP3	malate synthase g
Vp2S01_2578	ENOG4105C5Q	Transcriptional regulator
Vp2S01_2579	ENOG4105D3R	alkyl hydroperoxide reductase
Vp2S01_2580	ENOG4106N3A	copper homeostasis protein cutc
Vp2S01_2581	ENOG4105CSR	polyphosphate kinase 2
Vp2S01_2583	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_2584	ENOG4105E2Z	phosphate ABC transporter (Permease
Vp2S01_2585	ENOG4105C8U	phosphate abc transporter
Vp2S01_2586	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Vp2S01_2587	ENOG4105C9X	ppx gppa phosphatase
Vp2S01_2589	ENOG4105BZU	Histidine kinase
Vp2S01_2590	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Vp2S01_2591	ENOG4105DH7	May be involved in recombination (By similarity)
Vp2S01_2592	ENOG4105CFP	Peptidase U32
Vp2S01_2593	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
Vp2S01_2602	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Vp2S01_2603	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Vp2S01_2604	ENOG4105C34	Pseudouridine synthase
Vp2S01_2605	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Vp2S01_2606	ENOG4105E4C	Lytic transglycosylase catalytic
Vp2S01_2607	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
Vp2S01_2609	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Vp2S01_2610	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
Vp2S01_2611	ENOG4107SC1	transglycosylase
Vp2S01_2612	ENOG4105C5H	ABC transporter
Vp2S01_2614	ENOG4105DR5	peptidase
Vp2S01_2615	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
Vp2S01_2616	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Vp2S01_2617	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
Vp2S01_2618	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
Vp2S01_2619	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Vp2S01_2623	ENOG4108HRK	Histidine kinase
Vp2S01_2624	ENOG4108NEV	two component transcriptional regulator, LytTR family
Vp2S01_2625	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Vp2S01_2626	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
Vp2S01_2627	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Vp2S01_2628	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Vp2S01_2629	ENOG4105DTN	riboflavin biosynthesis protein ribF
Vp2S01_2630	ENOG4105CJR	Integral membrane protein (MviN
Vp2S01_2631	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
Vp2S01_2632	ENOG41080HT	Transcriptional regulator, arsr family
Vp2S01_2633	ENOG41063Z6	transcriptional regulator, lysR family
Vp2S01_2636	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
Vp2S01_2637	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Vp2S01_2638	ENOG4105HF0	Membrane
Vp2S01_2639	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
Vp2S01_2640	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Vp2S01_2641	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
Vp2S01_2643	ENOG4105CPC	Aldo Keto reductase
Vp2S01_2645	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_2646	ENOG4105CRK	lysyL-tRNA synthetase
Vp2S01_2647	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Vp2S01_2648	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Vp2S01_2649	ENOG4105T95	Thiol disulfide interChange protein
Vp2S01_2650	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Vp2S01_2651	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
Vp2S01_2652	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
Vp2S01_2653	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
Vp2S01_2654	ENOG4105C1J	atp-dependent rna helicase
Vp2S01_2655	ENOG4105D1Q	UPF0246 protein
Vp2S01_2656	ENOG4105BZG	amino acid carrier protein
Vp2S01_2659	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
Vp2S01_2660	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Vp2S01_2661	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
Vp2S01_2662	ENOG4105D98	threonine synthase
Vp2S01_2663	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Vp2S01_2666	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
Vp2S01_2668	ENOG41065U4	response regulator
Vp2S01_2670	ENOG4105BZU	Histidine kinase
Vp2S01_2672	ENOG4105N5T	Radical SAM Protein
Vp2S01_2675	ENOG4105CBC	glutamate synthase
Vp2S01_2676	ENOG4105BZ8	glutamate synthase
Vp2S01_2678	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Vp2S01_2679	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
Vp2S01_2680	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Vp2S01_2681	ENOG4105EN6	Membrane
Vp2S01_2682	ENOG4105EJ9	Membrane
Vp2S01_2684	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Vp2S01_2685	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Vp2S01_2686	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Vp2S01_2687	ENOG4105M6F	mutator MutT protein
Vp2S01_2688	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Vp2S01_2690	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Vp2S01_2691	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Vp2S01_2692	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Vp2S01_2693	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
Vp2S01_2694	ENOG4105DFU	Cell wall formation (By similarity)
Vp2S01_2695	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Vp2S01_2697	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Vp2S01_2698	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Vp2S01_2699	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
Vp2S01_2700	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Vp2S01_2701	ENOG4105CJN	penicillin-binding protein
Vp2S01_2702	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
Vp2S01_2703	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Vp2S01_2704	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Vp2S01_2706	ENOG41082RQ	UPF0102 protein
Vp2S01_2707	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Vp2S01_2708	ENOG4105W4M	Transport-associated protein
Vp2S01_2709	ENOG4105KB2	stringent starvation protein b
Vp2S01_2710	ENOG4107MKT	Stringent starvation protein a
Vp2S01_2711	ENOG4105EIX	cytochrome c1
Vp2S01_2712	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Vp2S01_2713	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Vp2S01_2714	ENOG4108UJD	30S ribosomal protein S9
Vp2S01_2715	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Vp2S01_2716	ENOG4105D6Z	AFG1 family ATPase
Vp2S01_2717	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
Vp2S01_2719	ENOG4105C0H	protease
Vp2S01_2720	ENOG4105C0H	protease
Vp2S01_2721	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Vp2S01_2722	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Vp2S01_2723	ENOG4105IPS	esterase
Vp2S01_2724	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
Vp2S01_2725	ENOG4108SX3	cytoplasmic protein
Vp2S01_2726	ENOG41087AY	ADP-Ribose pyrophosphatase
Vp2S01_2727	ENOG4105DFG	type I secretion outer membrane protein
Vp2S01_2728	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Vp2S01_2729	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
Vp2S01_2730	ENOG4108NVR	Methyl-accepting chemotaxis
Vp2S01_2732	ENOG4105I7R	Adenylate cyclase
Vp2S01_2733	ENOG4107IX6	phosphate transport regulator
Vp2S01_2734	ENOG4105CJ3	phosphate transporter
Vp2S01_2735	ENOG4106MWK	domain protein
Vp2S01_2738	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Vp2S01_2739	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Vp2S01_2740	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Vp2S01_2741	ENOG4107ZVW	dihydroneopterin aldolase
Vp2S01_2742	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Vp2S01_2743	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
Vp2S01_2744	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Vp2S01_2745	ENOG4105VCC	30S ribosomal protein S21
Vp2S01_2746	ENOG4105KTH	gatB Yqey
Vp2S01_2747	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Vp2S01_2748	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Vp2S01_2749	ENOG4105D01	(LipO)protein
Vp2S01_2756	ENOG4105CTS	PTS system mannitol-specific
Vp2S01_2757	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
Vp2S01_2758	ENOG4105E61	Mannitol repressor protein
Vp2S01_2759	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
Vp2S01_2760	ENOG4105GR3	Histidine kinase
Vp2S01_2763	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Vp2S01_2764	ENOG410804X	Transcriptional regulator
Vp2S01_2765	ENOG4105CA9	Pyruvate kinase
Vp2S01_2767	ENOG4105BZU	Histidine kinase
Vp2S01_2768	ENOG4108ZP8	Acetolactate synthase small subunit
Vp2S01_2769	ENOG4105C7K	acetolactate synthase
Vp2S01_2770	ENOG4108IQE	Amp-dependent synthetase and ligase
Vp2S01_2771	ENOG41064T2	transcriptional regulator, lysR family
Vp2S01_2775	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Vp2S01_2776	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Vp2S01_2777	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Vp2S01_2778	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Vp2S01_2780	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
Vp2S01_2781	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
Vp2S01_2782	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Vp2S01_2783	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Vp2S01_2784	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Vp2S01_2785	ENOG4105NWN	ApaG protein
Vp2S01_2786	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
Vp2S01_2787	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
Vp2S01_2789	ENOG4105DWK	Membrane
Vp2S01_2790	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Vp2S01_2791	ENOG4105K46	50S ribosomal protein l27
Vp2S01_2792	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Vp2S01_2793	ENOG4105EAH	synthase
Vp2S01_2795	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Vp2S01_2796	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
Vp2S01_2801	ENOG4107T0D	ABC, transporter
Vp2S01_2802	ENOG4106SMU	thiamine transporter membrane protein
Vp2S01_2803	ENOG4105DP9	ABC transporter
Vp2S01_2804	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Vp2S01_2805	ENOG4105DFU	Cell wall formation (By similarity)
Vp2S01_2806	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Vp2S01_2807	ENOG4105F0N	pyrophosphate phospho-hydrolase
Vp2S01_2809	ENOG41066HZ	AIG2-like family
Vp2S01_2810	ENOG4105MA0	exported protein
Vp2S01_2811	ENOG4105CFU	surface antigen
Vp2S01_2812	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Vp2S01_2813	ENOG41061GZ	Protein of unknown function (DUF1107)
Vp2S01_2814	ENOG4108UUE	Transcriptional regulator
Vp2S01_2817	ENOG4108I0Y	(ABC) transporter
Vp2S01_2821	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
Vp2S01_2823	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
Vp2S01_2824	ENOG4105C11	sulfate adenylyltransferase), subunit 2
Vp2S01_2825	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Vp2S01_2826	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
Vp2S01_2828	ENOG4105C1J	atp-dependent rna helicase
Vp2S01_2829	ENOG4107YB6	acetyltransferase, (GNAT) family
Vp2S01_2831	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Vp2S01_2833	ENOG4108ZT0	50S ribosomal protein l17
Vp2S01_2834	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Vp2S01_2835	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Vp2S01_2836	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Vp2S01_2837	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Vp2S01_2839	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Vp2S01_2840	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Vp2S01_2841	ENOG4105VPB	50S ribosomal protein L30
Vp2S01_2842	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Vp2S01_2844	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Vp2S01_2845	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Vp2S01_2846	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Vp2S01_2847	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Vp2S01_2848	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Vp2S01_2849	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Vp2S01_2850	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Vp2S01_2851	ENOG41083MP	50s ribosomal protein l29
Vp2S01_2852	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Vp2S01_2853	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Vp2S01_2854	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Vp2S01_2855	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Vp2S01_2856	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Vp2S01_2857	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Vp2S01_2858	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Vp2S01_2859	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Vp2S01_2860	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Vp2S01_2861	ENOG4105VFB	Binds the 23S rRNA (By similarity)
Vp2S01_2862	ENOG4105C25	Primosomal protein n'
Vp2S01_2863	ENOG4105ETE	Transcriptional regulator (LacI family
Vp2S01_2865	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Vp2S01_2866	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Vp2S01_2869	ENOG4108YGG	dna repair protein
Vp2S01_2875	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
Vp2S01_2876	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
Vp2S01_2877	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
Vp2S01_2880	ENOG4105CBT	Fructose-1,6-bisphosphatase
Vp2S01_2885	ENOG4105CP7	Triose-phosphate isomerase
Vp2S01_2886	ENOG4105CY0	Metallo-Beta-Lactamase
Vp2S01_2887	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Vp2S01_2890	ENOG4105D3Q	Sugar transferase
Vp2S01_2894	ENOG4105E2K	Glycosyl transferase (Group 1
Vp2S01_2895	ENOG4105JEU	Glycosyl transferase, family 2
Vp2S01_2899	ENOG4108UW5	maltose o-acetyltransferase
Vp2S01_2900	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Vp2S01_2901	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Vp2S01_2911	ENOG4105E3R	(LipO)protein
Vp2S01_2912	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
Vp2S01_2913	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
Vp2S01_2914	ENOG4105XA0	heptosyltransferase ii
Vp2S01_2915	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Vp2S01_2917	ENOG4107RA4	Glycosyl transferase (Group 1
Vp2S01_2922	ENOG4108UW5	maltose o-acetyltransferase
Vp2S01_2925	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Vp2S01_2926	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
Vp2S01_2927	ENOG41080IJ	Diacylglycerol kinase
Vp2S01_2928	ENOG4105DKP	glycosyl transferase, family 9
Vp2S01_2929	ENOG4106WTF	Glycosyl transferase, family 2
Vp2S01_2930	ENOG4105CPK	Glycosyl transferase (Group 1
Vp2S01_2931	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Vp2S01_2932	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
Vp2S01_2933	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Vp2S01_2936	ENOG4105KDC	50s ribosomal protein l28
Vp2S01_2937	ENOG4105W5Q	DNA repair protein (RadC
Vp2S01_2938	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_2939	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Vp2S01_2940	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
Vp2S01_2941	ENOG4105D1S	lipid A biosynthesis
Vp2S01_2942	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Vp2S01_2943	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Vp2S01_2944	ENOG4105DSJ	YicC domain protein
Vp2S01_2951	ENOG4108YGG	dna repair protein
Vp2S01_2958	ENOG4108MA7	Inherit from COG: YD repeat protein
Vp2S01_2959	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Vp2S01_2966	ENOG4108JQ7	(ABC) transporter
Vp2S01_2968	ENOG4107QRA	Extracellular solute-binding protein, family 5
Vp2S01_2969	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
Vp2S01_2970	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
Vp2S01_2971	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
Vp2S01_2975	ENOG4109015	Biopolymer transport protein exbD tolR
Vp2S01_2978	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Vp2S01_2979	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Vp2S01_2980	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Vp2S01_2981	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
Vp2S01_2982	ENOG4105CB5	ATP-dependent DNA helicase recG
Vp2S01_2984	ENOG4105C2W	permease
Vp2S01_2985	ENOG4105E0F	Histidine kinase
Vp2S01_2986	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Vp2S01_2988	ENOG4108RRZ	Transcription elongation factor GreB
Vp2S01_2990	ENOG4105BZM	domain protein
Vp2S01_2992	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
Vp2S01_2993	ENOG4105MJ2	Competence protein
Vp2S01_2994	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
Vp2S01_2995	ENOG4107RK2	ADP-ribose diphosphatase NudE
Vp2S01_2997	ENOG4105PIC	general secretion pathway protein N
Vp2S01_2998	ENOG4105U1E	general secretion pathway protein M
Vp2S01_2999	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
Vp2S01_3000	ENOG4108RTD	type II secretion system protein K
Vp2S01_3001	ENOG4108WWZ	General secretion pathway protein J
Vp2S01_3002	ENOG4105X5Z	General secretion pathway protein I
Vp2S01_3003	ENOG4105VWV	general secretion pathway protein h
Vp2S01_3004	ENOG4108VAU	general secretion pathway protein G
Vp2S01_3005	ENOG4105D7Q	type ii secretion system
Vp2S01_3006	ENOG4107QHF	type ii secretion system protein e
Vp2S01_3008	ENOG4108XKW	General secretion pathway protein C
Vp2S01_3009	ENOG4105VEJ	Heat shock protein
Vp2S01_3010	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Vp2S01_3011	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
Vp2S01_3013	ENOG4105SUU	thioesterase domain
Vp2S01_3014	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Vp2S01_3015	ENOG4107S2Z	UPF0761 membrane protein
Vp2S01_3020	ENOG4105C5F	glutamine synthetase
Vp2S01_3022	ENOG4105CUX	Signal transduction histidine kinase
Vp2S01_3023	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_3024	ENOG4105BZU	Histidine kinase
Vp2S01_3025	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Vp2S01_3026	ENOG4105D4P	Coproporphyrinogen iii oxidase
Vp2S01_3027	ENOG4105XCT	Protein of unknown function (DUF2489)
Vp2S01_3028	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
Vp2S01_3030	ENOG4106RE7	Cytochrome
Vp2S01_3031	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Vp2S01_3032	ENOG4105C2M	dna polymerase I
Vp2S01_3034	ENOG4105D52	delta-aminolevulinic acid dehydratase
Vp2S01_3035	ENOG4105F8V	Hydrolase, tatD family
Vp2S01_3037	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Vp2S01_3038	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
Vp2S01_3039	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Vp2S01_3040	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
Vp2S01_3041	ENOG4105JC1	sterol-binding domain protein
Vp2S01_3042	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Vp2S01_3043	ENOG4105CGY	Dna recombination protein
Vp2S01_3045	ENOG4105BZU	Histidine kinase
Vp2S01_3046	ENOG4105DSF	transport protein
Vp2S01_3056	ENOG4105K3G	Periplasmic Protein
Vp2S01_3057	ENOG4108JUA	Transcriptional regulator
Vp2S01_3058	ENOG4105CBX	hi0933 family
Vp2S01_3059	ENOG4108V6B	universal stress protein B
Vp2S01_3060	ENOG41090A1	ferritin
Vp2S01_3061	ENOG4108M6U	Universal stress protein A
Vp2S01_3062	ENOG4105EMK	carboxylate amino acid amine transporter
Vp2S01_3064	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
Vp2S01_3065	ENOG4105BZU	Histidine kinase
Vp2S01_3066	ENOG4108VVK	transcriptional Regulator, AsnC
Vp2S01_3067	ENOG4105DGW	oligopeptidase A
Vp2S01_3068	ENOG4105D6S	protein involved in catabolism of external DNA
Vp2S01_3069	ENOG4105DC8	reductase
Vp2S01_3070	ENOG4107RSM	transcriptional regulator
Vp2S01_3071	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
Vp2S01_3072	ENOG4108UHU	Aldolase
Vp2S01_3073	ENOG4105C6Z	Gluconate
Vp2S01_3074	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
Vp2S01_3075	ENOG4105C01	Dihydroxy-acid dehydratase
Vp2S01_3076	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
Vp2S01_3077	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
Vp2S01_3078	ENOG41064T2	transcriptional regulator, lysR family
Vp2S01_3079	ENOG4105DIQ	Transcriptional regulator
Vp2S01_3080	ENOG4105D9P	serine threonine protein kinase
Vp2S01_3086	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Vp2S01_3087	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Vp2S01_3088	ENOG4105DEF	Extracellular solute-binding protein, family 5
Vp2S01_3089	ENOG4108JQ6	ABC transporter
Vp2S01_3091	ENOG4105MPD	Cytochrome
Vp2S01_3092	ENOG4105C4R	Atp-dependent dna helicase
Vp2S01_3093	ENOG41067SE	Tetr family transcriptional regulator
Vp2S01_3094	ENOG410624X	efflux transporter, rnd family, mfp subunit
Vp2S01_3095	ENOG4105BZS	acriflavin resistance protein
Vp2S01_3096	ENOG4105W0Z	cytoplasmic protein
Vp2S01_3097	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Vp2S01_3098	ENOG4105EMY	transcriptional regulator
Vp2S01_3102	ENOG4108Z0R	Transferase
Vp2S01_3103	ENOG4105SG3	Protein of unknown function (DUF1488)
Vp2S01_3104	ENOG4105E2X	shikimate dehydrogenase
Vp2S01_3105	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
Vp2S01_3106	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Vp2S01_3107	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Vp2S01_3108	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Vp2S01_3109	ENOG4108WI1	Dna topoisomerase
Vp2S01_3111	ENOG4108RPN	Protein smg homolog
Vp2S01_3112	ENOG4105C79	DNA protecting protein DprA
Vp2S01_3114	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Vp2S01_3115	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Vp2S01_3116	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Vp2S01_3117	ENOG4105C1A	potassium transporter peripheral membrane
Vp2S01_3118	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Vp2S01_3120	ENOG4108UT2	hemolysin iii
Vp2S01_3121	ENOG4108N23	SpoOM-related protein
Vp2S01_3124	ENOG4105PC1	Conserved Protein
Vp2S01_3126	ENOG4105E27	serine threonine protein kinase
Vp2S01_3127	ENOG4108Z33	Thiol disulfide Interchange Protein
Vp2S01_3128	ENOG4106HNH	Acyl-transferase
Vp2S01_3130	ENOG4105C0P	Mg chelatase subunit ChlI
Vp2S01_3132	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
Vp2S01_3133	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Vp2S01_3134	ENOG4105C01	Dihydroxy-acid dehydratase
Vp2S01_3135	ENOG4105C7B	Threonine dehydratase
Vp2S01_3136	ENOG4105F52	Transcriptional regulator
Vp2S01_3137	ENOG4105CZQ	inner membrane transport protein YdhC
Vp2S01_3139	ENOG4105EAD	ABC transporter
Vp2S01_3140	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Vp2S01_3141	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Vp2S01_3142	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Vp2S01_3143	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Vp2S01_3144	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Vp2S01_3145	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Vp2S01_3146	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Vp2S01_3147	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Vp2S01_3148	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
Vp2S01_3149	ENOG410684E	atp synthase
Vp2S01_3150	ENOG4105FA0	parb-like partition protein
Vp2S01_3151	ENOG4107QJE	Chromosome Partitioning Protein
Vp2S01_3152	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Vp2S01_3153	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
Vp2S01_A0004	ENOG4108HRK	Histidine kinase
Vp2S01_A0005	ENOG4108VAC	response regulator
Vp2S01_A0007	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Vp2S01_A0008	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_A0013	ENOG4105D6U	Sodium Glutamate Symporter
Vp2S01_A0015	ENOG4105DVE	abc transporter atp-binding protein
Vp2S01_A0016	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Vp2S01_A0017	ENOG4105D6U	Sodium Glutamate Symporter
Vp2S01_A0019	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
Vp2S01_A0023	ENOG4105C2I	pirin domain protein
Vp2S01_A0024	ENOG4108VGI	doxx family
Vp2S01_A0026	ENOG4105D03	DNA-3-methyladenine glycosylase II
Vp2S01_A0027	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Vp2S01_A0031	ENOG4105DN9	Na H antiporter
Vp2S01_A0038	ENOG4105NBK	UPF0345 protein
Vp2S01_A0040	ENOG4108K0B	C-di-gmp phosphodiesterase
Vp2S01_A0042	ENOG4105UQX	Mate efflux family protein
Vp2S01_A0043	ENOG4105D3G	Pseudouridine synthase
Vp2S01_A0046	ENOG4105EJC	lysr family transcriptional regulator
Vp2S01_A0047	ENOG4108HCJ	Hydrolase
Vp2S01_A0049	ENOG4108KHX	Diguanylate cyclase
Vp2S01_A0051	ENOG4105C4W	S-formylglutathione hydrolase
Vp2S01_A0053	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
Vp2S01_A0054	ENOG4105CC0	LysR family Transcriptional regulator
Vp2S01_A0057	ENOG4105J4Q	Transcriptional regulator
Vp2S01_A0058	ENOG4105CHR	reductase
Vp2S01_A0059	ENOG4105P66	Membrane
Vp2S01_A0060	ENOG4105M5J	Cupin 2, conserved barrel domain protein
Vp2S01_A0063	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
Vp2S01_A0064	ENOG4108UHU	Aldolase
Vp2S01_A0069	ENOG4105CAZ	oligogalacturonide lyase
Vp2S01_A0070	ENOG4105Q26	Siderophore-interacting protein
Vp2S01_A0072	ENOG4105EW9	transcriptional regulator AsnC family
Vp2S01_A0076	ENOG4107W31	Pentapeptide repeat protein
Vp2S01_A0078	ENOG4105EIF	outer membrane protein W
Vp2S01_A0080	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Vp2S01_A0084	ENOG4107WCA	isomerase
Vp2S01_A0085	ENOG4108UVJ	appr-1-p processing domain protein
Vp2S01_A0086	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
Vp2S01_A0087	ENOG4108WAV	Transcriptional regulator
Vp2S01_A0090	ENOG4105C4X	radical SAM domain protein
Vp2S01_A0091	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
Vp2S01_A0092	ENOG4105DUM	transcriptional regulator, lysR family
Vp2S01_A0102	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
Vp2S01_A0103	ENOG4105C6Z	Gluconate
Vp2S01_A0104	ENOG4105BZW	Glycerate kinase
Vp2S01_A0105	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Vp2S01_A0112	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Vp2S01_A0114	ENOG4105CUW	cytochrome C-TYPE protein
Vp2S01_A0115	ENOG4107QY8	reductase
Vp2S01_A0117	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Vp2S01_A0118	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
Vp2S01_A0119	ENOG4105ETU	transcriptional activator (TenA
Vp2S01_A0120	ENOG4107Z6I	Thiamine biosynthesis protein
Vp2S01_A0121	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
Vp2S01_A0122	ENOG4108YI8	ABC transporter
Vp2S01_A0123	ENOG4105DWF	phosphomethylpyrimidine kinase
Vp2S01_A0126	ENOG4108TEM	pseudouridine methyltransferase
Vp2S01_A0129	ENOG4108YYI	Protein of unknown function (DUF2810)
Vp2S01_A0130	ENOG4105C5I	Dehydrogenase
Vp2S01_A0132	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
Vp2S01_A0133	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Vp2S01_A0134	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Vp2S01_A0135	ENOG410804D	Sensor Signal Transduction Histidine Kinase
Vp2S01_A0140	ENOG4109015	Biopolymer transport protein exbD tolR
Vp2S01_A0148	ENOG4105DSE	periplasmic solute binding protein
Vp2S01_A0149	ENOG4105DIK	(ABC) transporter
Vp2S01_A0150	ENOG4105CC5	ABC transporter
Vp2S01_A0153	ENOG4105CUG	Oligopeptidase b
Vp2S01_A0155	ENOG4105E5M	Multidrug resistance protein D
Vp2S01_A0156	ENOG4105CYW	agmatinase
Vp2S01_A0157	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
Vp2S01_A0159	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Vp2S01_A0160	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Vp2S01_A0163	ENOG4105DUM	transcriptional regulator, lysR family
Vp2S01_A0172	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_A0173	ENOG4105BZU	Histidine kinase
Vp2S01_A0174	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
Vp2S01_A0177	ENOG4105D5U	fad dependent oxidoreductase
Vp2S01_A0179	ENOG4105C0F	tryptophanase EC 4.1.99.1
Vp2S01_A0182	ENOG4105D9N	nucleoside
Vp2S01_A0184	ENOG4105CF1	Alkylated DNA repair protein
Vp2S01_A0185	ENOG4105BZU	Histidine kinase
Vp2S01_A0186	ENOG4108N3W	hemolysin secretion protein
Vp2S01_A0189	ENOG4106TD9	Diguanylate cyclase
Vp2S01_A0190	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
Vp2S01_A0191	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
Vp2S01_A0193	ENOG4105E0X	reductase
Vp2S01_A0194	ENOG4108UKZ	OsmC family
Vp2S01_A0195	ENOG4108UW5	maltose o-acetyltransferase
Vp2S01_A0202	ENOG4105JQN	Transcriptional regulator
Vp2S01_A0203	ENOG4105PAD	Hydrolase
Vp2S01_A0206	ENOG4108UUE	Transcriptional regulator
Vp2S01_A0208	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
Vp2S01_A0210	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
Vp2S01_A0211	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Vp2S01_A0213	ENOG4105KUU	lipolytic protein G-D-S-L family
Vp2S01_A0214	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Vp2S01_A0219	ENOG4105ETE	Transcriptional regulator (LacI family
Vp2S01_A0220	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
Vp2S01_A0221	ENOG4108JPW	Aminotransferase
Vp2S01_A0222	ENOG4107STF	Involved in phosphonate degradation (By similarity)
Vp2S01_A0226	ENOG4107RCV	ABC transporter, permease
Vp2S01_A0230	ENOG4108MJ5	VirK protein
Vp2S01_A0231	ENOG4105CJP	fad dependent oxidoreductase
Vp2S01_A0234	ENOG4105ETT	transcriptional Regulator, LysR family
Vp2S01_A0238	ENOG4105DUX	Transporter
Vp2S01_A0240	ENOG4105EJQ	L-serine dehydratase
Vp2S01_A0244	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Vp2S01_A0245	ENOG4105E4C	Lytic transglycosylase catalytic
Vp2S01_A0249	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
Vp2S01_A0250	ENOG4108ZC9	flagellar basal-body rod protein flgc
Vp2S01_A0251	ENOG4105W00	Flagellar hook capping protein
Vp2S01_A0252	ENOG4105BZE	flagellar hook protein, FlgE
Vp2S01_A0253	ENOG4108KPB	Flagellar basal-body rod protein FlgF
Vp2S01_A0254	ENOG4105CGA	flagellar basal-body rod protein FlgG
Vp2S01_A0255	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Vp2S01_A0256	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Vp2S01_A0257	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
Vp2S01_A0258	ENOG4105E1Q	flagellar hook-associated protein
Vp2S01_A0259	ENOG4105DTJ	flagellar hook-associated protein
Vp2S01_A0264	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
Vp2S01_A0270	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
Vp2S01_A0271	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Vp2S01_A0272	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Vp2S01_A0275	ENOG4105N14	lysine exporter protein LysE YggA
Vp2S01_A0279	ENOG4107Z3H	Transcriptional regulator, TetR family
Vp2S01_A0281	ENOG4105CGH	5'-nucleotidase
Vp2S01_A0282	ENOG4105EA8	2-Nitropropane dioxygenase
Vp2S01_A0283	ENOG4105DM4	PTS System
Vp2S01_A0287	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Vp2S01_A0288	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
Vp2S01_A0289	ENOG4105N2W	Transcriptional regulator
Vp2S01_A0291	ENOG4105CH6	catalase
Vp2S01_A0293	ENOG4108RWI	nicotinamidase
Vp2S01_A0296	ENOG4107RH7	Nicotinate phosphoribosyltransferase
Vp2S01_A0301	ENOG4105ETT	transcriptional Regulator, LysR family
Vp2S01_A0305	ENOG4105RW8	MltA-interacting MipA family protein
Vp2S01_A0306	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
Vp2S01_A0307	ENOG4105VYW	UPF0251 protein
Vp2S01_A0312	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Vp2S01_A0313	ENOG4107S8C	mandelate racemase muconate lactonizing
Vp2S01_A0315	ENOG4105RQF	LysR family Transcriptional regulator
Vp2S01_A0318	ENOG4108Z4X	TRANSCRIPTIONal
Vp2S01_A0323	ENOG4107RZC	phospholipase d
Vp2S01_A0329	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_A0337	ENOG41086KC	Transcriptional regulator
Vp2S01_A0339	ENOG4105BZU	Histidine kinase
Vp2S01_A0343	ENOG4107KET	secretion protein, HlyD family
Vp2S01_A0346	ENOG4107RUE	extracellular solute-binding protein family 1
Vp2S01_A0347	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Vp2S01_A0351	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Vp2S01_A0352	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Vp2S01_A0353	ENOG4105HDK	L-asparaginase
Vp2S01_A0354	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Vp2S01_A0359	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
Vp2S01_A0361	ENOG4108ZX5	transcriptional regulator
Vp2S01_A0362	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
Vp2S01_A0364	ENOG4105CPQ	Dehydrogenase
Vp2S01_A0365	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Vp2S01_A0368	ENOG4107RSM	transcriptional regulator
Vp2S01_A0370	ENOG4105C1J	atp-dependent rna helicase
Vp2S01_A0379	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Vp2S01_A0380	ENOG410874W	AraC family transcriptional regulator
Vp2S01_A0386	ENOG4105CKW	Inner membrane protein yedI
Vp2S01_A0387	ENOG4105EKE	dihydroorotase
Vp2S01_A0389	ENOG4105QVC	MOSC domain-containing protein
Vp2S01_A0389	ENOG4105QVC	MOSC domain-containing protein
Vp2S01_A0390	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
Vp2S01_A0391	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Vp2S01_A0399	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_A0400	ENOG4105EHG	Permease protein
Vp2S01_A0402	ENOG4106GFD	transport protein
Vp2S01_A0403	ENOG41090AP	transport protein
Vp2S01_A0404	ENOG4105WQ5	TonB family
Vp2S01_A0405	ENOG4105D4P	Coproporphyrinogen iii oxidase
Vp2S01_A0406	ENOG41090JE	Utilization Protein
Vp2S01_A0407	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
Vp2S01_A0410	ENOG4107R88	Chemotaxis protein (CheV)
Vp2S01_A0412	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
Vp2S01_A0413	ENOG4107TII	Recombinase
Vp2S01_A0418	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Vp2S01_A0420	ENOG4105G2Y	Transcriptional regulator
Vp2S01_A0421	ENOG4105CNH	Multidrug resistance protein MdtL
Vp2S01_A0425	ENOG4105I82	acetyl xylan esterase
Vp2S01_A0427	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Vp2S01_A0433	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
Vp2S01_A0436	ENOG4105C5Q	Transcriptional regulator
Vp2S01_A0440	ENOG4105KXC	Collagenase
Vp2S01_A0445	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Vp2S01_A0446	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
Vp2S01_A0447	ENOG4108M6U	Universal stress protein A
Vp2S01_A0448	ENOG4105C5H	ABC transporter
Vp2S01_A0451	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Vp2S01_A0453	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
Vp2S01_A0455	ENOG4108HK0	-acetyltransferase
Vp2S01_A0457	ENOG410620I	Diguanylate cyclase
Vp2S01_A0462	ENOG4108IJF	Heavy metal efflux pump, CzcA
Vp2S01_A0466	ENOG4108IEG	Formate dehydrogenase Alpha subunit
Vp2S01_A0470	ENOG4107QWP	ABC-2 type transporter
Vp2S01_A0471	ENOG4105CJ1	ABC, transporter
Vp2S01_A0474	ENOG4108NVR	Methyl-accepting chemotaxis
Vp2S01_A0476	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
Vp2S01_A0477	ENOG4105JAB	phenazine biosynthesis protein, phzf family
Vp2S01_A0478	ENOG4108V1U	phospholipid-binding protein
Vp2S01_A0480	ENOG4105D6J	arsenicaL-resistance protein
Vp2S01_A0483	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
Vp2S01_A0484	ENOG4105CTS	PTS system mannitol-specific
Vp2S01_A0485	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
Vp2S01_A0487	ENOG4107Z1W	Fructose transport system kinase
Vp2S01_A0492	ENOG4105E0U	tyrosine-specific transport protein
Vp2S01_A0494	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_A0495	ENOG4105DWD	nucleoside recognition domain protein
Vp2S01_A0499	ENOG4105DR5	peptidase
Vp2S01_A0501	ENOG4105CR8	Transcriptional regulator
Vp2S01_A0502	ENOG4105E5M	Multidrug resistance protein D
Vp2S01_A0505	ENOG4105VW4	glutaredoxin 3
Vp2S01_A0506	ENOG4108SXK	Transporter Drug Metabolite Exporter family
Vp2S01_A0512	ENOG4105SUT	Transcriptional Regulator AraC Family
Vp2S01_A0518	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
Vp2S01_A0519	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
Vp2S01_A0523	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
Vp2S01_A0524	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Vp2S01_A0525	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Vp2S01_A0531	ENOG4105VEQ	Cold shock protein
Vp2S01_A0533	ENOG4107SDU	Methyl-accepting chemotaxis
Vp2S01_A0534	ENOG4105BZU	Histidine kinase
Vp2S01_A0537	ENOG4107R34	abc transporter permease protein
Vp2S01_A0538	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Vp2S01_A0541	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_A0542	ENOG4108RMU	ferritin dps family protein
Vp2S01_A0545	ENOG4105C0A	alcohol dehydrogenase
Vp2S01_A0546	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
Vp2S01_A0554	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Vp2S01_A0555	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Vp2S01_A0556	ENOG4105MIR	Phenylalanine 4-monooxygenase
Vp2S01_A0557	ENOG41090A4	Pterin carbinolamine dehydratase
Vp2S01_A0561	ENOG4105VRT	cytoplasmic protein
Vp2S01_A0562	ENOG4105C1J	atp-dependent rna helicase
Vp2S01_A0563	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
Vp2S01_A0564	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Vp2S01_A0566	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
Vp2S01_A0568	ENOG4105CKI	cobalamin synthesis protein
Vp2S01_A0569	ENOG4105C1J	atp-dependent rna helicase
Vp2S01_A0573	ENOG4105CXC	rtn protein
Vp2S01_A0574	ENOG4105DKW	ABC transporter
Vp2S01_A0575	ENOG4108N3W	hemolysin secretion protein
Vp2S01_A0577	ENOG4105DUM	transcriptional regulator, lysR family
Vp2S01_A0578	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
Vp2S01_A0579	ENOG4105C4X	radical SAM domain protein
Vp2S01_A0582	ENOG4107S17	Phosphate-binding protein
Vp2S01_A0585	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
Vp2S01_A0586	ENOG4105C1J	atp-dependent rna helicase
Vp2S01_A0587	ENOG4105BZU	Histidine kinase
Vp2S01_A0588	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Vp2S01_A0589	ENOG4107SDU	Methyl-accepting chemotaxis
Vp2S01_A0592	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Vp2S01_A0593	ENOG4105CGU	Enoyl-CoA hydratase
Vp2S01_A0594	ENOG4107QX3	carboxylase
Vp2S01_A0595	ENOG4105C1G	acyl-Coa dehydrogenase
Vp2S01_A0597	ENOG4105CHU	acetyl-coa acetyltransferase
Vp2S01_A0598	ENOG4105C26	Dehydrogenase
Vp2S01_A0600	ENOG4105E39	Enoyl-CoA hydratase
Vp2S01_A0601	ENOG4105E39	Enoyl-CoA hydratase
Vp2S01_A0602	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Vp2S01_A0603	ENOG4105CHR	reductase
Vp2S01_A0604	ENOG4105E2S	oxidase) subunit II
Vp2S01_A0605	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Vp2S01_A0606	ENOG4105CCU	oxidase (Subunit III)
Vp2S01_A0608	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Vp2S01_A0609	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Vp2S01_A0614	ENOG4105C26	Dehydrogenase
Vp2S01_A0619	ENOG4107Y60	(LipO)protein
Vp2S01_A0623	ENOG4105E5Z	arginine transporter ATP-binding subunit
Vp2S01_A0624	ENOG4106PMH	Extracellular solute-binding protein family 3
Vp2S01_A0625	ENOG4105GBT	ABC transporter
Vp2S01_A0626	ENOG4105DMR	ABC, transporter
Vp2S01_A0628	ENOG4105DUM	transcriptional regulator, lysR family
Vp2S01_A0629	ENOG4107MKT	Stringent starvation protein a
Vp2S01_A0630	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Vp2S01_A0631	ENOG4107QSN	dihydrolipoamide acetyltransferase
Vp2S01_A0632	ENOG4105CPP	Dehydrogenase, E1 component
Vp2S01_A0633	ENOG4107RUY	(E1 component), alpha subunit
Vp2S01_A0636	ENOG4105R8A	Heat shock protein
Vp2S01_A0643	ENOG4105DHS	permease protein
Vp2S01_A0644	ENOG4105CM4	permease protein
Vp2S01_A0645	ENOG4108IPW	abc transporter atp-binding protein
Vp2S01_A0646	ENOG4108Z6Z	Transcriptional regulator
Vp2S01_A0656	ENOG4105EM2	membrane
Vp2S01_A0657	ENOG41088T4	Helicase IV
Vp2S01_A0658	ENOG4108Z5K	methylglyoxal synthase
Vp2S01_A0659	ENOG4108SV3	Tmao reductase system periplasmic protein tort
Vp2S01_A0660	ENOG4105BZU	Histidine kinase
Vp2S01_A0663	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Vp2S01_A0664	ENOG4105ENH	Sulfatase
Vp2S01_A0665	ENOG4105ENH	Sulfatase
Vp2S01_A0668	ENOG4105ENH	Sulfatase
Vp2S01_A0669	ENOG4105C4X	radical SAM domain protein
Vp2S01_A0670	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Vp2S01_A0676	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Vp2S01_A0677	ENOG41064T2	transcriptional regulator, lysR family
Vp2S01_A0678	ENOG4107TE5	Lipid kinase
Vp2S01_A0679	ENOG4108YDI	single-species biofilm formation on inanimate substrate
Vp2S01_A0682	ENOG4105C4X	radical SAM domain protein
Vp2S01_A0684	ENOG4105F2V	VRR-NUC domain-containing protein
Vp2S01_A0687	ENOG4105D0M	Protease HtpX homolog
Vp2S01_A0688	ENOG4108V0P	LemA family
Vp2S01_A0689	ENOG4105CEE	C4-dicarboxylate transporter
Vp2S01_A0693	ENOG4108MGY	Histidine kinase
Vp2S01_A0694	ENOG4107KBT	8-Amino-7-oxononanoate synthase
Vp2S01_A0695	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
Vp2S01_A0697	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
Vp2S01_A0698	ENOG4105C4X	radical SAM domain protein
Vp2S01_A0706	ENOG4108YGG	dna repair protein
Vp2S01_A0708	ENOG4105C0A	alcohol dehydrogenase
Vp2S01_A0709	ENOG4105C0A	alcohol dehydrogenase
Vp2S01_A0710	ENOG4107W7X	Aldolase
Vp2S01_A0711	ENOG4105NWF	RbsD or FucU transport
Vp2S01_A0712	ENOG4105CMG	Carbohydrate kinase
Vp2S01_A0713	ENOG4105CMG	Carbohydrate kinase
Vp2S01_A0715	ENOG4105EDR	glucose galactose transporter
Vp2S01_A0716	ENOG4107EDW	L-fucose operon activator
Vp2S01_A0721	ENOG4105CS6	Rhs element vgr protein
Vp2S01_A0724	ENOG41090WB	Transposase is3 is911
Vp2S01_A0725	ENOG4105EQR	Transposase IS116 IS110 IS902
Vp2S01_A0738	ENOG4108M8H	domain protein
Vp2S01_A0745	ENOG4105EQR	Transposase IS116 IS110 IS902
Vp2S01_A0746	ENOG41090WB	Transposase is3 is911
Vp2S01_A0750	ENOG4107SDU	Methyl-accepting chemotaxis
Vp2S01_A0753	ENOG4105D70	Integrase catalytic subunit
Vp2S01_A0756	ENOG4105F5W	AtP-binding protein
Vp2S01_A0759	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_A0762	ENOG4108M8H	domain protein
Vp2S01_A0790	ENOG41090WB	Transposase is3 is911
Vp2S01_A0793	ENOG4107HQ7	repeat protein
Vp2S01_A0794	ENOG4107QNK	)-transporter
Vp2S01_A0796	ENOG4108NZE	NAGC-like transcriptional regulator
Vp2S01_A0797	ENOG4105CGH	5'-nucleotidase
Vp2S01_A0802	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Vp2S01_A0808	ENOG4105DFP	Integrase
Vp2S01_A0810	ENOG4105KXC	Collagenase
Vp2S01_A0812	ENOG4106R3P	AraC family transcriptional regulator
Vp2S01_A0827	ENOG4105CDV	Ompa motb domain protein
Vp2S01_A0829	ENOG4108WAV	Transcriptional regulator
Vp2S01_A0830	ENOG41064T2	transcriptional regulator, lysR family
Vp2S01_A0832	ENOG4105BZU	Histidine kinase
Vp2S01_A0833	ENOG4105BZU	Histidine kinase
Vp2S01_A0834	ENOG4108WQH	regulatoR
Vp2S01_A0835	ENOG4105BZU	Histidine kinase
Vp2S01_A0837	ENOG4108WQH	regulatoR
Vp2S01_A0841	ENOG4107R88	Chemotaxis protein (CheV)
Vp2S01_A0844	ENOG4105FR1	rard protein
Vp2S01_A0846	ENOG4106CKV	Pap2 superfamily protein
Vp2S01_A0850	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
Vp2S01_A0854	ENOG4107RGH	Aldehyde dehydrogenase
Vp2S01_A0856	ENOG4107QPK	)-transporter
Vp2S01_A0858	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
Vp2S01_A0859	ENOG4106YYS	transcriptional regulatory protein
Vp2S01_A0861	ENOG4105CBC	glutamate synthase
Vp2S01_A0863	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
Vp2S01_A0869	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Vp2S01_A0870	ENOG4108UYE	Lactoylglutathione lyase
Vp2S01_A0874	ENOG4105CJW	magnesium transporter
Vp2S01_A0878	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Vp2S01_A0882	ENOG4105HDD	phospholipase
Vp2S01_A0883	ENOG4105HDD	phospholipase
Vp2S01_A0888	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Vp2S01_A0890	ENOG4105CR8	Transcriptional regulator
Vp2S01_A0892	ENOG4105C5W	Aldolase
Vp2S01_A0896	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Vp2S01_A0897	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Vp2S01_A0898	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Vp2S01_A0906	ENOG4105DM4	PTS System
Vp2S01_A0907	ENOG4105DE4	1-phosphofructokinase
Vp2S01_A0908	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
Vp2S01_A0909	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
Vp2S01_A0913	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
Vp2S01_A0914	ENOG4105DRP	amino acid AbC transporter
Vp2S01_A0915	ENOG4106TNF	Periplasmic binding protein
Vp2S01_A0916	ENOG4105E5Q	amino acid AbC transporter
Vp2S01_A0917	ENOG4105CDA	abc transporter atp-binding protein
Vp2S01_A0918	ENOG4105CA9	Pyruvate kinase
Vp2S01_A0919	ENOG4105CXY	transporter
Vp2S01_A0920	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
Vp2S01_A0922	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
Vp2S01_A0924	ENOG4108I6A	alcohol dehydrogenase
Vp2S01_A0925	ENOG4105CF7	AraC family transcriptional regulator
Vp2S01_A0927	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Vp2S01_A0928	ENOG4105CKU	formyltetrahydrofolate synthetase
Vp2S01_A0929	ENOG4107RE1	Inosine-guanosine kinase
Vp2S01_A0932	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Vp2S01_A0933	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Vp2S01_A0937	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
Vp2S01_A0938	ENOG4105C1J	atp-dependent rna helicase
Vp2S01_A0939	ENOG4108M8H	domain protein
Vp2S01_A0942	ENOG4105DS1	cytochrome b561
Vp2S01_A0943	ENOG4108YYC	ycei family
Vp2S01_A0944	ENOG4105TMB	Formate nitrite transporter
Vp2S01_A0945	ENOG4105DUM	transcriptional regulator, lysR family
Vp2S01_A0947	ENOG4108UQ5	membrane protein YcdZ
Vp2S01_A0948	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
Vp2S01_A0949	ENOG4105CGH	5'-nucleotidase
Vp2S01_A0950	ENOG4105DU1	integral membrane protein, terc
Vp2S01_A0953	ENOG4108M0H	Extracellular lipase
Vp2S01_A0954	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
Vp2S01_A0958	ENOG4105KA0	thioesterase Superfamily protein
Vp2S01_A0960	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
Vp2S01_A0966	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Vp2S01_A0968	ENOG4105BZU	Histidine kinase
Vp2S01_A0969	ENOG4105RKW	reductase (By
Vp2S01_A0971	ENOG4108I0Y	(ABC) transporter
Vp2S01_A0972	ENOG4105CV6	ABC transporter, permease
Vp2S01_A0974	ENOG4107R7A	Allophanate hydrolase subunit 2
Vp2S01_A0975	ENOG4105P4J	Allophanate hydrolase, subunit 1
Vp2S01_A0976	ENOG4105E7W	lamb ycsf family protein
Vp2S01_A0977	ENOG4105BZU	Histidine kinase
Vp2S01_A0978	ENOG4105CMR	udp-glucose 4-epimerase
Vp2S01_A0981	ENOG4105CWB	LysR family transcriptional Regulator
Vp2S01_A0982	ENOG4105CD5	CoA-binding domain protein
Vp2S01_A0984	ENOG4105CPF	Cell wall formation (By similarity)
Vp2S01_A0986	ENOG4108ZJT	translation initiation factor, Sui1
Vp2S01_A0996	ENOG4105GVR	general secretion pathway protein D
Vp2S01_A0997	ENOG4105EJC	lysr family transcriptional regulator
Vp2S01_A0999	ENOG4108M6U	Universal stress protein A
Vp2S01_A1005	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Vp2S01_A1006	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Vp2S01_A1009	ENOG4105BZU	Histidine kinase
Vp2S01_A1013	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_A1014	ENOG4105E0C	molybdate abc transporter
Vp2S01_A1015	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
Vp2S01_A1016	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Vp2S01_A1017	ENOG4105WXI	Bacterial OB fold (BOF) protein
Vp2S01_A1020	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Vp2S01_A1021	ENOG4105CGF	Aromatic amino acid aminotransferase
Vp2S01_A1022	ENOG4105ECQ	AraC Family Transcriptional Regulator
Vp2S01_A1023	ENOG4107QI1	Mate efflux family protein
Vp2S01_A1024	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
Vp2S01_A1025	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
Vp2S01_A1029	ENOG4105BZS	acriflavin resistance protein
Vp2S01_A1035	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
Vp2S01_A1036	ENOG4105C5Q	Transcriptional regulator
Vp2S01_A1037	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Vp2S01_A1038	ENOG4105CXY	transporter
Vp2S01_A1039	ENOG4108KX4	response regulator
Vp2S01_A1040	ENOG4105BZU	Histidine kinase
Vp2S01_A1041	ENOG4105CXY	transporter
Vp2S01_A1042	ENOG4105EIP	mannose-6-phosphate isomerase
Vp2S01_A1046	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Vp2S01_A1047	ENOG4105K63	Thioredoxin
Vp2S01_A1048	ENOG4108ISG	Major Facilitator
Vp2S01_A1051	ENOG4107QI1	Mate efflux family protein
Vp2S01_A1052	ENOG4105VXR	cytoplasmic protein
Vp2S01_A1057	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
Vp2S01_A1060	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Vp2S01_A1061	ENOG4105TMB	Formate nitrite transporter
Vp2S01_A1062	ENOG4105WZK	nitrite reductase NADPH small subunit
Vp2S01_A1063	ENOG4107QZF	nitrite reductase NADPH large subunit
Vp2S01_A1064	ENOG4105NXH	GreA GreB family elongation factor
Vp2S01_A1069	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Vp2S01_A1074	ENOG4108NVR	Methyl-accepting chemotaxis
Vp2S01_A1075	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Vp2S01_A1079	ENOG4105CXG	d-lactate dehydrogenase
Vp2S01_A1080	ENOG4105CC0	LysR family Transcriptional regulator
Vp2S01_A1097	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
Vp2S01_A1098	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
Vp2S01_A1100	ENOG4105C5W	Aldolase
Vp2S01_A1101	ENOG4106RE7	Cytochrome
Vp2S01_A1102	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
Vp2S01_A1104	ENOG4105C2C	drug resistance transporter, Bcr CflA
Vp2S01_A1106	ENOG4105QNF	Outer membrane lipoprotein
Vp2S01_A1110	ENOG4105EYH	Exonuclease
Vp2S01_A1111	ENOG4107RFY	SbcCD D subunit
Vp2S01_A1115	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Vp2S01_A1124	ENOG4108ZF3	Phosphatase
Vp2S01_A1127	ENOG4106VK6	Flagellar motor protein
Vp2S01_A1131	ENOG4105D9P	serine threonine protein kinase
Vp2S01_A1136	ENOG4105F8J	Adenylate Guanylate cyclase
Vp2S01_A1139	ENOG4108IG5	Transcriptional regulator
Vp2S01_A1142	ENOG4107QZF	nitrite reductase NADPH large subunit
Vp2S01_A1143	ENOG4105D7T	ABC transporter
Vp2S01_A1144	ENOG4105DG7	nitrate ABC transporter
Vp2S01_A1150	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Vp2S01_A1154	ENOG4105C44	Serine transporter
Vp2S01_A1155	ENOG4105BZU	Histidine kinase
Vp2S01_A1159	ENOG4105G6Z	alkaline phosphatase
Vp2S01_A1162	ENOG4105ETX	regulatoR
Vp2S01_A1166	ENOG4108I5U	Uridine phosphorylase
Vp2S01_A1167	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
Vp2S01_A1169	ENOG4105ETE	Transcriptional regulator (LacI family
Vp2S01_A1170	ENOG4108RVA	ribokinase
Vp2S01_A1171	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
Vp2S01_A1172	ENOG4105CNN	ABC, transporter
Vp2S01_A1173	ENOG4105C2J	ABC transporter
Vp2S01_A1174	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
Vp2S01_A1175	ENOG4108K0B	C-di-gmp phosphodiesterase
Vp2S01_A1176	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Vp2S01_A1189	ENOG4105BZU	Histidine kinase
Vp2S01_A1190	ENOG4105CA0	peroxidase
Vp2S01_A1191	ENOG4105BZU	Histidine kinase
Vp2S01_A1193	ENOG4107QX8	SPFH domain, Band 7 family protein
Vp2S01_A1195	ENOG4108RCM	Nitroreductase
Vp2S01_A1196	ENOG4108IJ7	Glycine betaine
Vp2S01_A1197	ENOG4108HQS	Glycine betaine
Vp2S01_A1199	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
Vp2S01_A1200	ENOG4105C26	Dehydrogenase
Vp2S01_A1201	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
Vp2S01_A1202	ENOG4105BZU	Histidine kinase
Vp2S01_A1204	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Vp2S01_A1206	ENOG4105E39	Enoyl-CoA hydratase
Vp2S01_A1207	ENOG4105C1G	acyl-Coa dehydrogenase
Vp2S01_A1208	ENOG4105C26	Dehydrogenase
Vp2S01_A1209	ENOG4105CHU	acetyl-coa acetyltransferase
Vp2S01_A1211	ENOG4105C1G	acyl-Coa dehydrogenase
Vp2S01_A1212	ENOG4107QX3	carboxylase
Vp2S01_A1213	ENOG4108IPT	Naphthoate synthase
Vp2S01_A1215	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Vp2S01_A1216	ENOG4105BZU	Histidine kinase
Vp2S01_A1219	ENOG4105EGS	Mechanosensitive ion channel
Vp2S01_A1220	ENOG4108UW5	maltose o-acetyltransferase
Vp2S01_A1221	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Vp2S01_A1222	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Vp2S01_A1223	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Vp2S01_A1225	ENOG4108S58	Phenazine biosynthesis protein PhzF
Vp2S01_A1226	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
Vp2S01_A1229	ENOG4105G9V	cytochrome C
Vp2S01_A1232	ENOG4105FQ6	thiopurine methyltransferase
Vp2S01_A1233	ENOG4105DZS	Phenylacetate-CoA ligase
Vp2S01_A1234	ENOG4108IV0	ABC, transporter
Vp2S01_A1239	ENOG4105C0Z	ABC transporter
Vp2S01_A1241	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Vp2S01_A1242	ENOG4105BZJ	Electron transfer flavoprotein
Vp2S01_A1243	ENOG4105C10	Electron transfer flavoprotein
Vp2S01_A1244	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Vp2S01_A1245	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Vp2S01_A1246	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Vp2S01_A1248	ENOG4108UNF	response regulator
Vp2S01_A1249	ENOG4107RGM	aldo keto reductase
Vp2S01_A1252	ENOG4105CMQ	Chloride channel
Vp2S01_A1255	ENOG4105C5A	transporter
Vp2S01_A1257	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Vp2S01_A1258	ENOG4105D06	uba thif-type nad fad binding protein
Vp2S01_A1262	ENOG4105KHC	sulfurtransferase
Vp2S01_A1263	ENOG4105BZU	Histidine kinase
Vp2S01_A1268	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Vp2S01_A1269	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Vp2S01_A1270	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
Vp2S01_A1271	ENOG4105DXI	Major Facilitator superfamily
Vp2S01_A1272	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Vp2S01_A1273	ENOG4105UYK	outer membrane protein a
Vp2S01_A1274	ENOG4107VXZ	Hydrolase
Vp2S01_A1275	ENOG4108YZN	class I peptide chain release factor
Vp2S01_A1276	ENOG4108N3W	hemolysin secretion protein
Vp2S01_A1279	ENOG4107YWA	deoxycytidylate deaminase
Vp2S01_A1280	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Vp2S01_A1283	ENOG4105WH1	Two component transcriptional regulator luxr family
Vp2S01_A1284	ENOG4105BZU	Histidine kinase
Vp2S01_A1287	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Vp2S01_A1289	ENOG4105CUW	cytochrome C-TYPE protein
Vp2S01_A1291	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
Vp2S01_A1293	ENOG4105CHU	acetyl-coa acetyltransferase
Vp2S01_A1297	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Vp2S01_A1298	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Vp2S01_A1303	ENOG4105EW9	transcriptional regulator AsnC family
Vp2S01_A1307	ENOG4105EFX	secretion protein, HlyD family
Vp2S01_A1309	ENOG4105BZU	Histidine kinase
Vp2S01_A1310	ENOG4108QGH	periplasmic
Vp2S01_A1311	ENOG41082IR	Excinuclease ABC C subunit domain protein
Vp2S01_A1312	ENOG4108YXG	UPF0502 protein
Vp2S01_A1315	ENOG41090HJ	UPF0265 protein
Vp2S01_A1317	ENOG4105EE0	oxidoreductase
Vp2S01_A1318	ENOG4105BZU	Histidine kinase
Vp2S01_A1322	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
Vp2S01_A1323	ENOG4108XM1	transcriptional regulator AsnC family
Vp2S01_A1324	ENOG4105DVH	amino acid
Vp2S01_A1327	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
Vp2S01_A1328	ENOG4105CJW	magnesium transporter
Vp2S01_A1329	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
Vp2S01_A1330	ENOG4105DZC	cytosine deaminase
Vp2S01_A1332	ENOG4105EST	Metal Dependent Phosphohydrolase
Vp2S01_A1334	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
Vp2S01_A1336	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Vp2S01_A1340	ENOG4108Z33	Thiol disulfide Interchange Protein
Vp2S01_A1343	ENOG4105EMU	Dehydrogenase
Vp2S01_A1344	ENOG4107EXC	regulatoR
Vp2S01_A1345	ENOG4105JJR	Histidine kinase
Vp2S01_A1347	ENOG41080IJ	Diacylglycerol kinase
Vp2S01_A1348	ENOG4105DIJ	Phosphoethanolamine transferase
Vp2S01_A1349	ENOG4105EP9	oxidoreductase
Vp2S01_A1355	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
Vp2S01_A1357	ENOG4108NRW	Phospholipase, patatin family
Vp2S01_A1358	ENOG4105EUB	pirin domain protein
Vp2S01_A1359	ENOG4105VEQ	Cold shock protein
Vp2S01_A1361	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Vp2S01_A1364	ENOG4105DZ1	carboxypeptidase
Vp2S01_A1366	ENOG4105CYM	Glutathione S-transferase
Vp2S01_A1368	ENOG4105NAE	bifunctional deaminase-reductase domain protein
Vp2S01_A1375	ENOG4105CHR	reductase
Vp2S01_A1378	ENOG4108P3C	
Vp2S01_A1382	ENOG4105EG2	ABC transporter, permease
Vp2S01_A1383	ENOG4105D56	permease protein
Vp2S01_A1384	ENOG4107FKK	extracellular solute-binding protein family 1
Vp2S01_A1385	ENOG4108IJ9	(ABC) transporter
Vp2S01_A1386	ENOG4105D3Q	Sugar transferase
Vp2S01_A1389	ENOG4105D75	Capsular exopolysaccharide family
Vp2S01_A1391	ENOG4105CPK	Glycosyl transferase (Group 1
Vp2S01_A1397	ENOG4105V0I	UPF0267 protein
Vp2S01_A1398	ENOG4108WUH	Transcriptional regulator, TetR family
Vp2S01_A1399	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
Vp2S01_A1400	ENOG4108RXX	maleylacetoacetate isomerase
Vp2S01_A1401	ENOG4105CH6	catalase
Vp2S01_A1402	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Vp2S01_A1403	ENOG4105DM4	PTS System
Vp2S01_A1404	ENOG4108YRF	PTS System
Vp2S01_A1406	ENOG4106R3P	AraC family transcriptional regulator
Vp2S01_A1407	ENOG4105DM4	PTS System
Vp2S01_A1408	ENOG4105EIP	mannose-6-phosphate isomerase
Vp2S01_A1410	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
Vp2S01_A1412	ENOG4105BZU	Histidine kinase
Vp2S01_A1413	ENOG4105CZN	Potassium uptake protein
Vp2S01_A1416	ENOG4105BZU	Histidine kinase
Vp2S01_A1417	ENOG4105BZ1	(ABC) transporter
Vp2S01_A1418	ENOG4105E0K	tonB-dependent siderophore receptor
Vp2S01_A1419	ENOG4105E0A	ABC, transporter
Vp2S01_A1420	ENOG4108HUF	Transporter
Vp2S01_A1421	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
Vp2S01_A1423	ENOG4105KCK	Peptidoglycan-associated lipoprotein
Vp2S01_A1427	ENOG4108JJ6	Type I secretion system ATPase
Vp2S01_A1429	ENOG41086KC	Transcriptional regulator
Vp2S01_A1430	ENOG41086KC	Transcriptional regulator
Vp2S01_A1432	ENOG41069D7	Methyl-accepting chemotaxis
Vp2S01_A1434	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Vp2S01_A1441	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Vp2S01_A1442	ENOG4105E2Z	phosphate ABC transporter (Permease
Vp2S01_A1443	ENOG4105C8U	phosphate abc transporter
Vp2S01_A1444	ENOG4107S17	Phosphate-binding protein
Vp2S01_A1446	ENOG4108NVR	Methyl-accepting chemotaxis
Vp2S01_A1450	ENOG4105D05	Receptor
Vp2S01_A1451	ENOG4105CUG	Oligopeptidase b
Vp2S01_A1452	ENOG4105C1J	atp-dependent rna helicase
Vp2S01_A1454	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
Vp2S01_A1455	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
Vp2S01_A1456	ENOG4108XDN	Transcriptional regulator
Vp2S01_A1457	ENOG4107SEY	Conserved Protein
Vp2S01_A1458	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
Vp2S01_A1461	ENOG4106TD9	Diguanylate cyclase
Vp2S01_A1462	ENOG4105KK7	inner membrane protein YiaW
Vp2S01_A1463	ENOG4105EFX	secretion protein, HlyD family
Vp2S01_A1464	ENOG4108V7D	UPF0397 protein
Vp2S01_A1465	ENOG4108JJB	ABC transporter
Vp2S01_A1468	ENOG4105GXZ	Ferredoxin-type protein NapH
Vp2S01_A1469	ENOG4108BGM	Quinol dehydrogenase periplasmic component
Vp2S01_A1470	ENOG4105WCN	acetyltransferase
Vp2S01_A1473	ENOG4105YE1	PilZ domain
Vp2S01_A1474	ENOG4108NVR	Methyl-accepting chemotaxis
Vp2S01_A1475	ENOG4105DAN	ATP-dependent protease
Vp2S01_A1478	ENOG4108JQ5	ABC transporter
Vp2S01_A1480	ENOG4105CR8	Transcriptional regulator
Vp2S01_A1481	ENOG4105DAA	L-lactate
Vp2S01_A1482	ENOG4105DMF	Dehydrogenase
Vp2S01_A1484	ENOG4105D64	Mechanosensitive ion channel
Vp2S01_A1491	ENOG4105CPQ	Dehydrogenase
Vp2S01_A1492	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Vp2S01_A1493	ENOG4105BZU	Histidine kinase
Vp2S01_A1494	ENOG4107R0W	ABC transporter
Vp2S01_A1496	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Vp2S01_A1498	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Vp2S01_A1503	ENOG4105EXG	Transcriptional regulator
Vp2S01_A1504	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
Vp2S01_A1509	ENOG4107SSZ	Phosphatase
Vp2S01_A1515	ENOG4108JIR	Flagellum-specific ATP synthase
Vp2S01_A1517	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Vp2S01_A1518	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
Vp2S01_A1520	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_A1523	ENOG4105DD5	Flagellar motor switch protein
Vp2S01_A1524	ENOG4105CN7	Flagellar biosynthetic protein FliP
Vp2S01_A1525	ENOG4105VS8	Flagellar biosynthetic protein fliq
Vp2S01_A1526	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Vp2S01_A1527	ENOG4105D00	flagellar biosynthetic protein flhB
Vp2S01_A1530	ENOG4105I03	Flagellin
Vp2S01_A1531	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
Vp2S01_A1532	ENOG4105MQ3	flagellar protein FliS
Vp2S01_A1537	ENOG4107RD7	Flagellar Motor Protein, MotA
Vp2S01_A1538	ENOG4105ER2	Ompa motb domain protein
Vp2S01_A1540	ENOG4105KWG	Pfam:DUF1696
Vp2S01_A1545	ENOG4105C6N	Formate acetyltransferase
Vp2S01_A1546	ENOG4105F1A	Pyruvate formate-lyase
Vp2S01_A1547	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Vp2S01_A1549	ENOG4105I4A	GCN5-related N-acetyltransferase
Vp2S01_A1552	ENOG4105CNH	Multidrug resistance protein MdtL
Vp2S01_A1553	ENOG4105G2Y	Transcriptional regulator
Vp2S01_A1557	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
Vp2S01_A1561	ENOG4105IPI	Membrane
Vp2S01_A1562	ENOG41068P6	UPF0319 protein
Vp2S01_A1564	ENOG4105DP0	ferredoxin-NADP reductase
Vp2S01_A1566	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
Vp2S01_A1567	ENOG4105ETT	transcriptional Regulator, LysR family
Vp2S01_A1569	ENOG4108RCM	Nitroreductase
Vp2S01_A1570	ENOG4108ZX5	transcriptional regulator
Vp2S01_A1572	ENOG4105DZ1	carboxypeptidase
Vp2S01_A1575	ENOG4105C72	UPF0176 protein
Vp2S01_A1576	ENOG4108M1A	Chitin-binding protein
Vp2S01_A1577	ENOG4108NRW	Phospholipase, patatin family
Vp2S01_A1578	ENOG41081FY	multiple antibiotic resistance (MarC)-related
Vp2S01_A1580	ENOG4105DAY	polysaccharide export protein
Vp2S01_A1582	ENOG4105D75	Capsular exopolysaccharide family
Vp2S01_A1584	ENOG4105N0V	mono-oxygenase ydhR
Vp2S01_A1585	ENOG4105F04	LysR family Transcriptional regulator
Vp2S01_A1587	ENOG4105CK2	sodium dicarboxylate symporter
Vp2S01_A1589	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Vp2S01_A1590	ENOG4108P2H	Inner membrane protein YjiG
Vp2S01_A1591	ENOG41074DU	domain protein
Vp2S01_A1594	ENOG4107T9C	Alpha amylase catalytic region
Vp2S01_A1595	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
Vp2S01_A1596	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Vp2S01_A1597	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
Vp2S01_A1598	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
Vp2S01_A1601	ENOG41061ZR	Transcriptional regulator
Vp2S01_A1607	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Vp2S01_A1608	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
Vp2S01_A1610	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
Vp2S01_A1612	ENOG4105D5Q	Arginine ornithine antiporter
Vp2S01_A1613	ENOG4105CXN	decarboxylase
Vp2S01_A1617	ENOG4108K8S	endonuclease I
Vp2S01_A1621	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
Vp2S01_A1626	ENOG4105DR5	peptidase
Vp2S01_A1628	ENOG4107RAN	Peptidase, M16
Vp2S01_A1629	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_A1630	ENOG4105E0A	ABC, transporter
Vp2S01_A1631	ENOG4108U1V	ABC transporter, permease
Vp2S01_A1632	ENOG4105DQ5	transport system permease protein
Vp2S01_A1633	ENOG4108HUF	Transporter
Vp2S01_A1634	ENOG4105GAV	receptor
Vp2S01_A1635	ENOG4105E0K	tonB-dependent siderophore receptor
Vp2S01_A1637	ENOG4105DUU	IucA IucC family protein
Vp2S01_A1639	ENOG4105DBM	Siderophore biosynthesis protein
Vp2S01_A1640	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Vp2S01_A1641	ENOG4108JP0	extracellular solute-binding protein family 1
Vp2S01_A1642	ENOG4105DHQ	Histidine kinase
Vp2S01_A1643	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Vp2S01_A1644	ENOG4105CI1	PTS System
Vp2S01_A1647	ENOG4105CNN	ABC, transporter
Vp2S01_A1648	ENOG4105C2J	ABC transporter
Vp2S01_A1649	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
Vp2S01_A1650	ENOG4105EF1	ribulokinase
Vp2S01_A1652	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
Vp2S01_A1657	ENOG4108ZHJ	Organic hydroperoxide resistance protein
Vp2S01_A1658	ENOG4105K56	Transcriptional regulator
Vp2S01_A1659	ENOG4105D3R	alkyl hydroperoxide reductase
Vp2S01_A1660	ENOG4108JU3	Alkyl hydroperoxide reductase
Vp2S01_A1663	ENOG4105EXG	Transcriptional regulator
Vp2S01_A1664	ENOG4105ECQ	AraC Family Transcriptional Regulator
Vp2S01_A1665	ENOG4105DU6	RNA polymerase
Vp2S01_A1668	ENOG4105C8Q	Methyl-accepting chemotaxis
Vp2S01_A1669	ENOG4105W8I	Transcriptional regulator
Vp2S01_A1670	ENOG4105F8D	glycoside hydrolase family 4
Vp2S01_A1673	ENOG4108RPX	mosc domain containing protein
Vp2S01_A1674	ENOG4105C1J	atp-dependent rna helicase
Vp2S01_A1675	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
Vp2S01_A1676	ENOG4105C6F	GntR Family Transcriptional Regulator
Vp2S01_A1677	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Vp2S01_A1678	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
Vp2S01_A1679	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Vp2S01_A1680	ENOG4105DEI	Mannitol dehydrogenase
Vp2S01_A1682	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
Vp2S01_A1683	ENOG4108UHU	Aldolase
Vp2S01_A1684	ENOG4105P66	Membrane
Vp2S01_A1688	ENOG4105CF7	AraC family transcriptional regulator
Vp2S01_A1690	ENOG4105BZ1	(ABC) transporter
Vp2S01_A1692	ENOG4105EW9	transcriptional regulator AsnC family
Vp2S01_A1699	ENOG4105CK7	Sodium proline symporter
Vp2S01_A1701	ENOG4105C26	Dehydrogenase
Vp2S01_A1705	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
Vp2S01_A1706	ENOG4105CQZ	Histidine kinase
Vp2S01_A1707	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Vp2S01_A1708	ENOG4107QZV	Type I secretion membrane fusion protein
Vp2S01_A1711	ENOG4108JJA	ABC, transporter
Vp2S01_A1716	ENOG4108J59	Extracellular solute-binding protein, family 5
Vp2S01_A1718	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
Vp2S01_A1719	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Vp2S01_A1720	ENOG4105C5Y	PTS System
Vp2S01_A1721	ENOG4105FCK	Membrane
Vp2S01_A1722	ENOG4105EC3	peptidase S51, dipeptidase E
Vp2S01_A1723	ENOG4105EQ2	LysR family Transcriptional regulator
Vp2S01_A1726	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
Vp2S01_A1727	ENOG4106RMF	ParB family
Vp2S01_A1732	ENOG4108JQ7	(ABC) transporter
Vp2S01_A1737	ENOG4105BZU	Histidine kinase
Vp2S01_A1739	ENOG4105CDY	transcriptional regulatory protein
Vp2S01_A1740	ENOG4105CNI	cell division protein FtsW
Vp2S01_A1744	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Vp2S01_p10003	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
Vp2S01_p10011	ENOG4107WZZ	SMC domain protein
Vp2S01_p10024	ENOG4107U4J	modification
Vp2S01_p10041	ENOG4108IYH	Dna topoisomerase