locus-tag	class	description
EHC70_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHC70_00010	COG0592	DNA-directed DNA polymerase activity
EHC70_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHC70_00020	COG0187	DNA topoisomerase II activity
EHC70_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
EHC70_00045	COG3977	Valine--pyruvate aminotransferase
EHC70_00050	COG0366	Alpha amylase catalytic
EHC70_00055	COG0751	glycine-tRNA ligase activity
EHC70_00060	COG0752	glycyl-tRNA synthetase alpha subunit
EHC70_00065	COG2119	membrane
EHC70_00075	COG0425	Belongs to the sulfur carrier protein TusA family
EHC70_00090	COG0604	alcohol dehydrogenase
EHC70_00095	COG0183	Belongs to the thiolase family
EHC70_00100	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC70_00100	COG1024	Enoyl-CoA hydratase
EHC70_00105	COG1739	Uncharacterized protein family UPF0029
EHC70_00110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC70_00175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHC70_00180	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EHC70_00185	COG0352	thiamine-phosphate diphosphorylase activity
EHC70_00190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC70_00195	COG2104	thiamine diphosphate biosynthetic process
EHC70_00200	COG2022	thiamine diphosphate biosynthetic process
EHC70_00210	COG0006	proline dipeptidase activity
EHC70_00210	COG0006	proline dipeptidase activity
EHC70_00240	COG3220	belongs to the UPF0276 family
EHC70_00250	COG0210	DNA helicase
EHC70_00260	COG0405	Gamma-glutamyltransferase
EHC70_00265	COG1280	lysine exporter protein (LysE YggA)
EHC70_00275	COG2962	Rard protein
EHC70_00280	COG0514	ATP-dependent DNA helicase (RecQ)
EHC70_00295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EHC70_00300	COG0248	Ppx GppA phosphatase
EHC70_00305	COG0513	Belongs to the DEAD box helicase family
EHC70_00310	COG3118	belongs to the thioredoxin family
EHC70_00315	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EHC70_00330	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EHC70_00335	COG0633	Ferredoxin
EHC70_00390	COG3071	HemY protein
EHC70_00395	COG2959	enzyme of heme biosynthesis
EHC70_00400	COG1587	Uroporphyrinogen-III synthase
EHC70_00405	COG0181	hydroxymethylbilane synthase activity
EHC70_00410	COG3072	Adenylate cyclase
EHC70_00415	COG1965	Belongs to the frataxin family
EHC70_00425	COG0019	diaminopimelate decarboxylase activity
EHC70_00430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHC70_00440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EHC70_00445	COG1011	Hydrolase
EHC70_00450	COG3287	FIST C domain
EHC70_00450	COG2199	diguanylate cyclase activity
EHC70_00450	COG2200	EAL domain
EHC70_00470	COG0561	phosphatase activity
EHC70_00480	COG2267	carboxylic ester hydrolase activity
EHC70_00485	COG1280	lysine exporter protein (LysE YggA)
EHC70_00490	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC70_00495	COG0640	Transcriptional regulator
EHC70_00500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC70_00555	COG2095	MarC family integral membrane protein
EHC70_00565	COG0742	ribosomal rna small subunit methyltransferase
EHC70_00570	COG0552	protein localization to endoplasmic reticulum
EHC70_00575	COG2884	Cell division ATP-binding protein ftsE
EHC70_00580	COG2177	Part of the ABC transporter FtsEX involved in
EHC70_00595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC70_00600	COG0705	Rhomboid family
EHC70_00605	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC70_00610	COG3161	chorismate lyase activity
EHC70_00615	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EHC70_00620	COG2937	Belongs to the GPAT DAPAT family
EHC70_00635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHC70_00640	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EHC70_00645	COG0534	Mate efflux family protein
EHC70_00650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC70_00740	COG2003	Belongs to the UPF0758 family
EHC70_00755	COG3339	Conserved Protein
EHC70_00800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHC70_00805	COG4206	TonB-dependent receptor
EHC70_00815	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EHC70_00880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC70_00890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EHC70_00925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC70_00935	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC70_00940	COG0250	Participates in transcription elongation, termination and antitermination
EHC70_00945	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHC70_00950	COG0081	regulation of translation
EHC70_00955	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHC70_00960	COG0222	ribosome binding
EHC70_00965	COG0085	RNA polymerase activity
EHC70_00970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHC70_00975	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EHC70_00980	COG2816	NAD+ diphosphatase activity
EHC70_00995	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EHC70_01000	COG1573	uracil-dna glycosylase
EHC70_01005	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC70_01010	COG3068	Protein conserved in bacteria
EHC70_01015	COG1253	flavin adenine dinucleotide binding
EHC70_01030	COG0151	Belongs to the GarS family
EHC70_01040	COG0138	bifunctional purine biosynthesis protein purh
EHC70_01050	COG0789	Transcriptional regulator
EHC70_01055	COG3710	Transcriptional regulator
EHC70_01065	COG0531	amino acid
EHC70_01070	COG1982	Orn Lys Arg decarboxylase major
EHC70_01140	COG3706	GGDEF domain
EHC70_01145	COG0488	(ABC) transporter
EHC70_01155	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EHC70_01160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC70_01165	COG2264	protein methyltransferase activity
EHC70_01175	COG0439	Biotin carboxylase
EHC70_01180	COG0511	ligase activity, forming carbon-carbon bonds
EHC70_01185	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EHC70_01190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC70_01205	COG2814	Major facilitator Superfamily
EHC70_01210	COG2198	Histidine kinase
EHC70_01210	COG0784	Response regulator, receiver
EHC70_01210	COG2205	protein histidine kinase activity
EHC70_01235	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC70_01245	COG3263	regulation of cellular component size
EHC70_01255	COG4232	protein-disulfide reductase activity
EHC70_01260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC70_01265	COG1027	Aspartate ammonia-lyase
EHC70_01270	COG3030	protein affecting phage T7 exclusion by the F plasmid
EHC70_01275	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EHC70_01285	COG2205	protein histidine kinase activity
EHC70_01290	COG0745	RESPONSE REGULATOR receiver
EHC70_01300	COG3678	ATP-independent chaperone mediated protein folding
EHC70_01310	COG0205	6-phosphofructokinase activity
EHC70_01315	COG0534	Mate efflux family protein
EHC70_01320	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC70_01325	COG0459	protein refolding
EHC70_01340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC70_01350	COG1509	lysine 2,3-aminomutase activity
EHC70_01355	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC70_01365	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC70_01370	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC70_01375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC70_01380	COG1053	succinate dehydrogenase
EHC70_01390	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EHC70_01410	COG4942	peptidase
EHC70_01415	COG1045	serine acetyltransferase
EHC70_01420	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EHC70_01425	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EHC70_01430	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC70_01435	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EHC70_01455	COG0688	phosphatidylethanolamine metabolic process
EHC70_01460	COG1162	GTPase activity
EHC70_01465	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EHC70_01535	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHC70_01540	COG0802	atpase or kinase
EHC70_01545	COG0860	N-Acetylmuramoyl-L-alanine amidase
EHC70_01550	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EHC70_01555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHC70_01565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHC70_01570	COG0330	HflC and HflK could
EHC70_01575	COG0330	HflC and HflK could
EHC70_01580	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EHC70_01585	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHC70_01595	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EHC70_01600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC70_01600	COG1017	nitric oxide dioxygenase activity
EHC70_01605	COG1959	2 iron, 2 sulfur cluster binding
EHC70_01610	COG0557	exoribonuclease II activity
EHC70_01615	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC70_01620	COG0546	phosphoglycolate phosphatase activity
EHC70_01625	COG0180	Tryptophanyl-tRNA synthetase
EHC70_01655	COG0512	Glutamine amidotransferase of anthranilate synthase
EHC70_01660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EHC70_01670	COG1012	belongs to the aldehyde dehydrogenase family
EHC70_01680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC70_01685	COG3954	Phosphoribulokinase
EHC70_01690	COG3089	Belongs to the UPF0270 family
EHC70_01695	COG0429	hydrolase of the alpha beta-hydrolase fold
EHC70_01705	COG0488	(ABC) transporter
EHC70_01715	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC70_01730	COG1047	Peptidyl-prolyl cis-trans
EHC70_01740	COG1446	asparaginase
EHC70_01745	COG2900	Belongs to the SlyX family
EHC70_01755	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC70_01760	COG2964	Protein conserved in bacteria
EHC70_01765	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EHC70_01770	COG2923	Belongs to the DsrF TusC family
EHC70_01775	COG2168	tRNA wobble position uridine thiolation
EHC70_01785	COG0049	tRNA binding
EHC70_01790	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC70_01795	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC70_01800	COG2906	2 iron, 2 sulfur cluster binding
EHC70_01810	COG0281	malic enzyme
EHC70_01820	COG0626	cystathionine gamma-synthase activity
EHC70_01825	COG0527	aspartate kinase activity
EHC70_01825	COG0460	homoserine dehydrogenase
EHC70_01830	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EHC70_01840	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EHC70_01845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC70_01850	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHC70_01855	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC70_01860	COG0137	argininosuccinate synthase activity
EHC70_01865	COG0165	Argininosuccinate lyase
EHC70_01865	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC70_01880	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC70_01880	COG0678	peroxiredoxin activity
EHC70_01890	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EHC70_01920	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHC70_01925	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHC70_01935	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EHC70_01940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EHC70_01945	COG0360	Binds together with S18 to 16S ribosomal RNA
EHC70_01950	COG2965	DNA replication, synthesis of RNA primer
EHC70_01960	COG0359	binds to the 23S rRNA
EHC70_01970	COG0305	Participates in initiation and elongation during chromosome replication
EHC70_01975	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC70_01985	COG0432	Pfam Uncharacterised protein family UPF0047
EHC70_01990	COG0166	Belongs to the GPI family
EHC70_02000	COG0735	belongs to the Fur family
EHC70_02010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC70_02035	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHC70_02040	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC70_02045	COG0175	sulfate reduction
EHC70_02130	COG1410	methionine synthase
EHC70_02130	COG0646	methionine synthase
EHC70_02135	COG0527	aspartate kinase activity
EHC70_02145	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EHC70_02155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EHC70_02170	COG0629	single-stranded DNA binding
EHC70_02175	COG2200	EAL domain
EHC70_02175	COG2199	diguanylate cyclase activity
EHC70_02200	COG3409	Peptidoglycan-binding domain 1 protein
EHC70_02200	COG3267	Type II secretory pathway component ExeA
EHC70_02210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC70_02215	COG1459	type II secretion system
EHC70_02260	COG1077	Cell shape determining protein MreB Mrl
EHC70_02265	COG1792	Involved in formation and maintenance of cell shape
EHC70_02270	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EHC70_02275	COG0424	maF-like protein
EHC70_02280	COG1530	ribonuclease E activity
EHC70_02285	COG3164	Protein of unknown function
EHC70_02290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC70_02295	COG0312	modulator of DNA gyrase
EHC70_02300	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EHC70_02305	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EHC70_02320	COG0564	pseudouridine synthase activity
EHC70_02325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC70_02330	COG3028	Belongs to the UPF0307 family
EHC70_02335	COG0312	modulator of DNA gyrase
EHC70_02340	COG2239	Acts as a magnesium transporter
EHC70_02345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC70_02350	COG1660	Displays ATPase and GTPase activities
EHC70_02355	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC70_02360	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC70_02370	COG1137	ATPase activity
EHC70_02375	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EHC70_02385	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EHC70_02385	COG0517	IMP dehydrogenase activity
EHC70_02395	COG1127	ABC transporter
EHC70_02400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EHC70_02405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC70_02410	COG2854	intermembrane phospholipid transfer
EHC70_02420	COG5007	Belongs to the BolA IbaG family
EHC70_02425	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHC70_02430	COG0204	Acyl-transferase
EHC70_02435	COG0251	oxidation-reduction process
EHC70_02440	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EHC70_02445	COG0540	Belongs to the ATCase OTCase family
EHC70_02455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHC70_02460	COG2235	arginine
EHC70_02490	COG0525	valine-tRNA ligase activity
EHC70_02495	COG2927	DNA polymerase III (CHI subunit)
EHC70_02500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC70_02505	COG0795	lipopolysaccharide-transporting ATPase activity
EHC70_02510	COG0795	lipopolysaccharide-transporting ATPase activity
EHC70_02520	COG4325	translation initiation factor activity
EHC70_02525	COG1028	Short-chain dehydrogenase reductase Sdr
EHC70_02535	COG0726	polysaccharide deacetylase
EHC70_02540	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC70_02545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC70_02550	COG1447	Phosphotransferase system cellobiose-specific component IIA
EHC70_02555	COG1486	melibiose metabolic process
EHC70_02560	COG3394	polysaccharide catabolic process
EHC70_02570	COG3437	response regulator, receiver
EHC70_02620	COG1012	belongs to the aldehyde dehydrogenase family
EHC70_02650	COG0840	transmembrane signaling receptor activity
EHC70_02690	COG0741	lytic transglycosylase activity
EHC70_02695	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EHC70_02705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EHC70_02715	COG2066	Belongs to the glutaminase family
EHC70_02720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC70_02725	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHC70_02735	COG1872	DUF167
EHC70_02740	COG0762	integral membrane protein
EHC70_02745	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHC70_02750	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EHC70_02765	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHC70_02770	COG1678	Uncharacterized ACR, COG1678
EHC70_02775	COG0189	ligase activity
EHC70_02780	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EHC70_02785	COG2356	endonuclease I
EHC70_02790	COG3091	SprT-like family
EHC70_02800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHC70_02810	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC70_02815	COG0583	DNA-binding transcription factor activity
EHC70_02820	COG4771	TonB-dependent receptor
EHC70_02825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC70_02830	COG0126	phosphoglycerate kinase activity
EHC70_02835	COG0191	fructose-bisphosphate aldolase activity
EHC70_02840	COG0668	transmembrane transport
EHC70_02845	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHC70_02855	COG0583	DNA-binding transcription factor activity
EHC70_02865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC70_02870	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EHC70_02875	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHC70_02885	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EHC70_02895	COG3079	Belongs to the UPF0149 family
EHC70_02900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC70_02905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC70_02920	COG0354	folic acid binding
EHC70_02925	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EHC70_02935	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EHC70_02945	COG1595	DNA-templated transcription, initiation
EHC70_02950	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EHC70_02960	COG3086	response to oxidative stress
EHC70_02965	COG0481	GTPase activity
EHC70_02970	COG0681	Belongs to the peptidase S26 family
EHC70_02975	COG0571	ribonuclease III activity
EHC70_02980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHC70_02985	COG1381	Involved in DNA repair and RecF pathway recombination
EHC70_02990	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EHC70_02995	COG0736	holo-[acyl-carrier-protein] synthase activity
EHC70_03010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHC70_03020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC70_03025	COG3956	TIGRFAM MazG family protein
EHC70_03030	COG0504	CTP synthase activity
EHC70_03035	COG0148	phosphopyruvate hydratase activity
EHC70_03040	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EHC70_03045	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHC70_03050	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EHC70_03055	COG0585	pseudouridine synthase activity
EHC70_03060	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EHC70_03065	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EHC70_03080	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHC70_03085	COG1546	Belongs to the CinA family
EHC70_03090	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHC70_03095	COG2137	regulation of response to DNA damage stimulus
EHC70_03100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC70_03105	COG0527	aspartate kinase activity
EHC70_03165	COG3630	sodium ion export across plasma membrane
EHC70_03170	COG5016	pyruvate
EHC70_03170	COG0511	ligase activity, forming carbon-carbon bonds
EHC70_03175	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EHC70_03180	COG1063	alcohol dehydrogenase
EHC70_03185	COG1238	metal cluster binding
EHC70_03190	COG0612	Peptidase, M16
EHC70_03195	COG2918	glutathione biosynthetic process
EHC70_03205	COG1854	S-ribosylhomocysteine lyase activity
EHC70_03210	COG4536	flavin adenine dinucleotide binding
EHC70_03215	COG4137	Cytochrome C assembly protein
EHC70_03220	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHC70_03225	COG0228	four-way junction DNA binding
EHC70_03230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHC70_03235	COG0336	Belongs to the RNA methyltransferase TrmD family
EHC70_03240	COG0335	large ribosomal subunit rRNA binding
EHC70_03245	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EHC70_03250	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EHC70_03255	COG0237	dephospho-CoA kinase activity
EHC70_03265	COG1459	type II secretion system
EHC70_03270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC70_03285	COG0157	Belongs to the NadC ModD family
EHC70_03295	COG2186	Transcriptional regulator
EHC70_03300	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EHC70_03305	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHC70_03310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC70_03325	COG0288	reversible hydration of carbon dioxide
EHC70_03330	COG0659	secondary active sulfate transmembrane transporter activity
EHC70_03340	COG1131	(ABC) transporter
EHC70_03345	COG0842	Transport permease protein
EHC70_03355	COG1560	Kdo2-lipid A biosynthetic process
EHC70_03365	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHC70_03370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EHC70_03375	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHC70_03390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC70_03400	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC70_03405	COG1489	DNA binding
EHC70_03410	COG1643	Atp-dependent helicase
EHC70_03415	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC70_03420	COG1752	Esterase of the alpha-beta hydrolase superfamily
EHC70_03425	COG1049	propionate catabolic process, 2-methylcitrate cycle
EHC70_03430	COG3112	Uncharacterised protein family (UPF0231)
EHC70_03440	COG0004	ammonium transporteR
EHC70_03445	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC70_03455	COG3842	ATPase activity
EHC70_03460	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC70_03475	COG2971	BadF BadG BcrA BcrD
EHC70_03485	COG4608	Belongs to the ABC transporter superfamily
EHC70_03490	COG0444	Belongs to the ABC transporter superfamily
EHC70_03495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC70_03505	COG0747	negative chemotaxis
EHC70_03510	COG2205	protein histidine kinase activity
EHC70_03510	COG0784	Response regulator, receiver
EHC70_03510	COG2198	Histidine kinase
EHC70_03510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC70_03520	COG2813	Specifically methylates the guanine in position
EHC70_03525	COG0628	permease
EHC70_03530	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHC70_03535	COG0316	Belongs to the HesB IscA family
EHC70_03545	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC70_03550	COG0739	heme binding
EHC70_03555	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC70_03565	COG2027	D-alanyl-D-alanine carboxypeptidase
EHC70_03570	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC70_03575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC70_03580	COG1534	Rna-binding protein
EHC70_03585	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EHC70_03590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHC70_03595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHC70_03600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC70_03610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC70_03625	COG0779	Required for maturation of 30S ribosomal subunits
EHC70_03630	COG0195	Participates in both transcription termination and antitermination
EHC70_03635	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHC70_03640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHC70_03645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHC70_03650	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHC70_03655	COG1185	polyribonucleotide nucleotidyltransferase activity
EHC70_03670	COG0534	Mate efflux family protein
EHC70_03695	COG3153	acetyltransferase
EHC70_03715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EHC70_03725	COG0084	hydrolase, TatD family'
EHC70_03730	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC70_03735	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHC70_03740	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EHC70_03745	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHC70_03750	COG0813	purine-nucleoside phosphorylase activity
EHC70_03760	COG0560	Phosphoserine phosphatase
EHC70_03770	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHC70_03775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC70_03780	COG0583	DNA-binding transcription factor activity
EHC70_03790	COG1022	Amp-dependent synthetase and ligase
EHC70_03795	COG2169	Transcriptional regulator
EHC70_03820	COG4964	Belongs to the GSP D family
EHC70_03880	COG0583	DNA-binding transcription factor activity
EHC70_03885	COG0531	amino acid
EHC70_03890	COG2731	YhcH YjgK YiaL family protein
EHC70_03895	COG3250	beta-galactosidase activity
EHC70_03900	COG1609	Transcriptional regulator
EHC70_03910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHC70_03920	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHC70_03925	COG2017	converts alpha-aldose to the beta-anomer
EHC70_03940	COG2211	Major facilitator Superfamily
EHC70_03945	COG1609	Transcriptional regulator
EHC70_03950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC70_03965	COG0598	Magnesium transport protein CorA
EHC70_03970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EHC70_03975	COG1349	DNA-binding transcription factor activity
EHC70_03980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHC70_03985	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC70_04000	COG2271	Major facilitator Superfamily
EHC70_04005	COG0584	glycerophosphoryl diester phosphodiesterase
EHC70_04010	COG2171	N-acyltransferase activity
EHC70_04035	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EHC70_04045	COG1074	ATP-dependent DNA helicase activity
EHC70_04050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EHC70_04060	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC70_04060	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC70_04075	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EHC70_04080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EHC70_04085	COG2166	iron-sulfur cluster assembly
EHC70_04090	COG3706	GGDEF domain
EHC70_04095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHC70_04100	COG0693	protein deglycase activity
EHC70_04105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHC70_04110	COG3248	Nucleoside-binding outer membrane protein
EHC70_04135	COG1595	DNA-templated transcription, initiation
EHC70_04155	COG3056	Lipoprotein
EHC70_04160	COG2813	Specifically methylates the guanine in position
EHC70_04165	COG0271	Belongs to the BolA IbaG family
EHC70_04170	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC70_04175	COG1805	sodium ion transport
EHC70_04180	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC70_04185	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC70_04190	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC70_04195	COG2871	sodium ion transport
EHC70_04200	COG1477	protein flavinylation
EHC70_04215	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHC70_04220	COG0514	ATP-dependent DNA helicase (RecQ)
EHC70_04225	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC70_04240	COG0733	neurotransmitter:sodium symporter activity
EHC70_04260	COG0442	prolyl-tRNA aminoacylation
EHC70_04265	COG1720	tRNA m6t6A37 methyltransferase activity
EHC70_04270	COG0254	rRNA binding
EHC70_04285	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC70_04290	COG1671	Belongs to the UPF0178 family
EHC70_04315	COG3098	single-species biofilm formation
EHC70_04330	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EHC70_04335	COG0024	Methionine aminopeptidase
EHC70_04340	COG0052	Belongs to the universal ribosomal protein uS2 family
EHC70_04345	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHC70_04350	COG0528	UMP kinase activity
EHC70_04355	COG0233	cytoplasmic translational termination
EHC70_04360	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHC70_04365	COG0575	Belongs to the CDS family
EHC70_04370	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EHC70_04375	COG0750	zinc metalloprotease
EHC70_04385	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EHC70_04390	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC70_04395	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC70_04400	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC70_04405	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC70_04410	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHC70_04415	COG0587	DNA-directed DNA polymerase activity
EHC70_04420	COG0825	malonyl-CoA metabolic process
EHC70_04425	COG0037	tRNA processing
EHC70_04435	COG0347	Belongs to the P(II) protein family
EHC70_04440	COG3021	interspecies interaction between organisms
EHC70_04450	COG0741	lytic transglycosylase activity
EHC70_04450	COG1388	LysM domain
EHC70_04455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC70_04460	COG2226	methyltransferase
EHC70_04465	COG0328	RNA-DNA hybrid ribonuclease activity
EHC70_04470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC70_04485	COG1960	acyl-CoA dehydrogenase activity
EHC70_04490	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC70_04495	COG0121	glutamine amidotransferase
EHC70_04500	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHC70_04505	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EHC70_04510	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHC70_04515	COG2233	PERMEase
EHC70_04535	COG1393	Belongs to the ArsC family
EHC70_04540	COG4783	chaperone-mediated protein folding
EHC70_04555	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EHC70_04560	COG2716	regulation of RNA biosynthetic process
EHC70_04565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC70_04585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC70_04590	COG1393	Belongs to the ArsC family
EHC70_04620	COG2837	iron assimilation
EHC70_04625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC70_04635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC70_04640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC70_04645	COG1334	flagellar protein FlaG
EHC70_04650	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHC70_04660	COG1516	flagellar protein fliS
EHC70_04670	COG4191	Histidine kinase
EHC70_04675	COG2204	response regulator
EHC70_04680	COG1677	Flagellar hook-basal body complex protein FliE
EHC70_04690	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC70_04740	COG1987	bacterial-type flagellum assembly
EHC70_04745	COG1684	flagellar biosynthetic protein fliR
EHC70_04765	COG0455	bacterial-type flagellum organization
EHC70_04780	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EHC70_04785	COG2198	Histidine kinase
EHC70_04785	COG0643	Histidine kinase
EHC70_04790	COG2201	protein-glutamate methylesterase activity
EHC70_04795	COG1192	Involved in chromosome partitioning
EHC70_04805	COG0835	chemotaxis
EHC70_04815	COG4133	protoheme IX ABC transporter activity
EHC70_04820	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC70_04825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC70_04830	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC70_04835	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EHC70_04840	COG1138	Cytochrome C-type biogenesis protein
EHC70_04845	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EHC70_04860	COG2853	Lipoprotein
EHC70_04870	COG2067	long-chain fatty acid transport protein
EHC70_04890	COG0183	Belongs to the thiolase family
EHC70_04895	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC70_04895	COG1024	Enoyl-CoA hydratase
EHC70_04910	COG2062	phosphohistidine phosphatase, SixA
EHC70_04915	COG2840	Smr protein MutS2
EHC70_04920	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC70_04925	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHC70_04930	COG2860	membrane
EHC70_04940	COG3101	peptidyl-lysine hydroxylation
EHC70_04955	COG0431	NADPH-dependent FMN reductase
EHC70_04960	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EHC70_04960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC70_04965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC70_04975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC70_04980	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC70_04990	COG0101	tRNA pseudouridine synthase activity
EHC70_04995	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC70_05000	COG0285	dihydrofolate synthase activity
EHC70_05005	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EHC70_05010	COG1286	toxin biosynthetic process
EHC70_05015	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHC70_05020	COG0583	DNA-binding transcription factor activity
EHC70_05025	COG0745	RESPONSE REGULATOR receiver
EHC70_05035	COG2832	Protein of unknown function (DUF454)
EHC70_05040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHC70_05050	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHC70_05055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHC70_05060	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC70_05065	COG0814	amino acid
EHC70_05070	COG0251	oxidation-reduction process
EHC70_05075	COG3681	Belongs to the UPF0597 family
EHC70_05090	COG2261	transglycosylase associated protein
EHC70_05095	COG2983	Belongs to the UPF0260 family
EHC70_05100	COG0668	transmembrane transport
EHC70_05105	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EHC70_05110	COG0346	lactoylglutathione lyase activity
EHC70_05120	COG1785	Belongs to the alkaline phosphatase family
EHC70_05140	COG2226	methyltransferase
EHC70_05155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC70_05160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC70_05170	COG3139	Protein of unknown function (DUF1315)
EHC70_05175	COG0252	asparaginase activity
EHC70_05180	COG0616	signal peptide processing
EHC70_05185	COG1902	pentaerythritol trinitrate reductase activity
EHC70_05185	COG0446	pyridine nucleotide-disulphide oxidoreductase
EHC70_05190	COG0778	Nitroreductase
EHC70_05195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC70_05215	COG0123	including yeast histone deacetylase and acetoin utilization protein
EHC70_05225	COG3083	sulfuric ester hydrolase activity
EHC70_05230	COG3082	Protein of unknown function (DUF1414)
EHC70_05235	COG3081	Nucleoid-associated protein
EHC70_05250	COG1757	Na H antiporter
EHC70_05255	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC70_05260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC70_05265	COG2095	MarC family integral membrane protein
EHC70_05270	COG1012	belongs to the aldehyde dehydrogenase family
EHC70_05270	COG1454	alcohol dehydrogenase
EHC70_05290	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EHC70_05300	COG2056	Na+-H+ antiporter family
EHC70_05305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC70_05320	COG2885	chlorophyll binding
EHC70_05330	COG0346	lactoylglutathione lyase activity
EHC70_05335	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHC70_05340	COG4660	Part of a membrane complex involved in electron transport
EHC70_05345	COG4659	FMN binding
EHC70_05350	COG4658	electron transport chain
EHC70_05355	COG4656	Part of a membrane complex involved in electron transport
EHC70_05360	COG2878	Part of a membrane complex involved in electron transport
EHC70_05365	COG4657	Part of a membrane complex involved in electron transport
EHC70_05380	COG0556	nucleotide-excision repair
EHC70_05385	COG2204	response regulator
EHC70_05390	COG2198	Histidine kinase
EHC70_05395	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EHC70_05400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHC70_05405	COG0521	Mo-molybdopterin cofactor biosynthetic process
EHC70_05410	COG0315	cyclic pyranopterin monophosphate synthase activity
EHC70_05415	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EHC70_05420	COG0314	molybdopterin synthase activity
EHC70_05430	COG0601	transmembrane transport
EHC70_05435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC70_05440	COG0444	Belongs to the ABC transporter superfamily
EHC70_05450	COG0435	Glutathione S-transferase
EHC70_05460	COG3174	membrane
EHC70_05465	COG0280	phosphate acetyltransferase
EHC70_05465	COG0857	belongs to the CobB CobQ family
EHC70_05470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC70_05475	COG3092	negative regulation of chromosome organization
EHC70_05485	COG4120	Belongs to the binding-protein-dependent transport system permease family
EHC70_05490	COG1122	ATPase activity
EHC70_05495	COG0366	Alpha amylase catalytic
EHC70_05500	COG3706	GGDEF domain
EHC70_05500	COG0745	RESPONSE REGULATOR receiver
EHC70_05505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC70_05510	COG0653	protein targeting
EHC70_05515	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EHC70_05520	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC70_05525	COG2186	Transcriptional regulator
EHC70_05535	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC70_05535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC70_05540	COG0489	protein tyrosine kinase activity
EHC70_05545	COG0572	uridine kinase
EHC70_05560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHC70_05595	COG1399	metal-binding, possibly nucleic acid-binding protein
EHC70_05605	COG0416	fatty acid biosynthetic process
EHC70_05610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC70_05640	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHC70_05645	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHC70_05655	COG0084	hydrolase, TatD family'
EHC70_05660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC70_05660	COG1263	PTS System
EHC70_05680	COG0733	neurotransmitter:sodium symporter activity
EHC70_05695	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC70_05700	COG0469	pyruvate kinase activity
EHC70_05705	COG1940	carbohydrate kinase activity
EHC70_05710	COG0784	Response regulator, receiver
EHC70_05710	COG0835	chemotaxis
EHC70_05715	COG0587	DNA-directed DNA polymerase activity
EHC70_05730	COG1028	Short-chain dehydrogenase reductase Sdr
EHC70_05735	COG0616	signal peptide processing
EHC70_05740	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EHC70_05745	COG0539	negative regulation of cytoplasmic translation
EHC70_05755	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EHC70_05760	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EHC70_05765	COG0284	orotidine-5'-phosphate decarboxylase activity
EHC70_05770	COG4166	transmembrane transport
EHC70_05795	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHC70_05805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC70_05805	COG3008	intermembrane lipid transfer
EHC70_05810	COG2995	paraquat-inducible protein a
EHC70_05815	COG3258	Cytochrome c
EHC70_05820	COG2863	cytochrome
EHC70_05860	COG4232	protein-disulfide reductase activity
EHC70_05865	COG3118	belongs to the thioredoxin family
EHC70_05895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC70_05905	COG0577	efflux transmembrane transporter activity
EHC70_05905	COG1136	(ABC) transporter
EHC70_05910	COG1136	(ABC) transporter
EHC70_05910	COG0577	efflux transmembrane transporter activity
EHC70_05915	COG0577	efflux transmembrane transporter activity
EHC70_05915	COG1136	(ABC) transporter
EHC70_05920	COG1335	isochorismatase
EHC70_05935	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC70_05965	COG3850	Histidine kinase
EHC70_05965	COG5002	protein histidine kinase activity
EHC70_05970	COG0745	RESPONSE REGULATOR receiver
EHC70_06025	COG0840	transmembrane signaling receptor activity
EHC70_06030	COG1032	radical SAM domain protein
EHC70_06035	COG3706	GGDEF domain
EHC70_06035	COG4251	negative regulation of phosphorylation
EHC70_06035	COG5001	Diguanylate cyclase
EHC70_06035	COG2203	Gaf domain
EHC70_06050	COG0583	DNA-binding transcription factor activity
EHC70_06060	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC70_06070	COG2350	Protein conserved in bacteria
EHC70_06075	COG1607	acyl-coa hydrolase
EHC70_06080	COG2917	probably involved in intracellular septation
EHC70_06100	COG1301	dicarboxylic acid transport
EHC70_06115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC70_06125	COG0159	tryptophan synthase activity
EHC70_06130	COG0133	tryptophan synthase activity
EHC70_06135	COG0134	indole-3-glycerol-phosphate synthase activity
EHC70_06135	COG0135	phosphoribosylanthranilate isomerase activity
EHC70_06140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHC70_06145	COG0512	Glutamine amidotransferase of anthranilate synthase
EHC70_06150	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC70_06160	COG0613	PHP domain protein
EHC70_06165	COG0009	L-threonylcarbamoyladenylate synthase
EHC70_06175	COG1187	pseudouridine synthase activity
EHC70_06185	COG3099	Belongs to the UPF0263 family
EHC70_06190	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC70_06200	COG0417	DNA replication proofreading
EHC70_06205	COG2197	response regulator
EHC70_06210	COG0322	excinuclease ABC activity
EHC70_06250	COG0019	diaminopimelate decarboxylase activity
EHC70_06275	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC70_06280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC70_06285	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC70_06305	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EHC70_06315	COG0437	4 iron, 4 sulfur cluster binding
EHC70_06320	COG3301	Polysulphide reductase, NrfD
EHC70_06325	COG1138	Cytochrome C-type biogenesis protein
EHC70_06335	COG3088	subunit of a heme lyase
EHC70_06335	COG4235	cytochrome complex assembly
EHC70_06345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC70_06370	COG2989	Protein conserved in bacteria
EHC70_06375	COG3108	Peptidase M15
EHC70_06380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC70_06395	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EHC70_06420	COG1846	Transcriptional regulator
EHC70_06425	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC70_06430	COG0840	transmembrane signaling receptor activity
EHC70_06450	COG1448	Aminotransferase
EHC70_06475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC70_06485	COG0017	Asparaginyl-tRNA synthetase
EHC70_06490	COG0840	transmembrane signaling receptor activity
EHC70_06495	COG0720	synthase
EHC70_06505	COG2200	EAL domain
EHC70_06510	COG1760	l-serine dehydratase
EHC70_06515	COG0814	amino acid
EHC70_06520	COG0494	nUDIX hydrolase
EHC70_06530	COG0784	Response regulator, receiver
EHC70_06530	COG2205	protein histidine kinase activity
EHC70_06535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC70_06555	COG3106	COG3106 Predicted ATPase
EHC70_06560	COG3768	UPF0283 membrane protein
EHC70_06570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC70_06855	COG0625	glutathione transferase activity
EHC70_07065	COG2314	TM2 domain
EHC70_07140	COG0494	nUDIX hydrolase
EHC70_07215	COG1757	Na H antiporter
EHC70_07220	COG0174	glutamine synthetase
EHC70_07230	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EHC70_07235	COG1917	Cupin 2, conserved barrel domain protein
EHC70_07235	COG1396	sequence-specific DNA binding
EHC70_07240	COG1012	belongs to the aldehyde dehydrogenase family
EHC70_07245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC70_07255	COG2957	Belongs to the agmatine deiminase family
EHC70_07260	COG1012	belongs to the aldehyde dehydrogenase family
EHC70_07265	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC70_07270	COG1227	inorganic diphosphatase activity
EHC70_07280	COG2771	luxR family
EHC70_07280	COG2200	EAL domain
EHC70_07295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC70_07310	COG1846	Transcriptional regulator
EHC70_07315	COG2315	Protein conserved in bacteria
EHC70_07335	COG0110	maltose O-acetyltransferase activity
EHC70_07365	COG3063	Type IV pilus biogenesis stability protein PilW
EHC70_07370	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EHC70_07385	COG0531	amino acid
EHC70_07395	COG1560	Kdo2-lipid A biosynthetic process
EHC70_07400	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EHC70_07405	COG1280	lysine exporter protein (LysE YggA)
EHC70_07415	COG1115	amino acid carrier protein
EHC70_07440	COG1368	sulfuric ester hydrolase activity
EHC70_07445	COG0642	Histidine kinase
EHC70_07450	COG0745	RESPONSE REGULATOR receiver
EHC70_07460	COG1028	Short-chain dehydrogenase reductase Sdr
EHC70_07480	COG2113	Glycine betaine
EHC70_07485	COG4176	ABC-type proline glycine betaine transport system permease component
EHC70_07505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC70_07510	COG0456	acetyltransferase
EHC70_07515	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC70_07520	COG0662	Cupin 2, conserved barrel domain protein
EHC70_07525	COG0527	aspartate kinase activity
EHC70_07530	COG1858	cytochrome C peroxidase
EHC70_07545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC70_07560	COG3290	protein histidine kinase activity
EHC70_07565	COG4565	transcriptional regulatory protein
EHC70_07570	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EHC70_07575	COG0363	glucosamine-6-phosphate deaminase activity
EHC70_07580	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHC70_07605	COG3284	Transcriptional regulator
EHC70_07610	COG1012	belongs to the aldehyde dehydrogenase family
EHC70_07680	COG4669	(LipO)protein
EHC70_07700	COG3177	Filamentation induced by cAMP protein fic
EHC70_07740	COG1073	alpha beta
EHC70_07745	COG1073	alpha beta
EHC70_07755	COG4792	protein secretion
EHC70_07760	COG4791	protein targeting
EHC70_07765	COG4794	Type iii secretion
EHC70_07770	COG4790	Type iii secretion
EHC70_07775	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC70_07840	COG0457	Tetratricopeptide repeat
EHC70_07860	COG0730	response to heat
EHC70_07890	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHC70_07895	COG0372	Belongs to the citrate synthase family
EHC70_07905	COG2828	Protein conserved in bacteria
EHC70_07930	COG0561	phosphatase activity
EHC70_07935	COG0602	queuosine metabolic process
EHC70_07940	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EHC70_07945	COG3706	GGDEF domain
EHC70_07985	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC70_07990	COG0840	transmembrane signaling receptor activity
EHC70_07995	COG1254	Belongs to the acylphosphatase family
EHC70_08000	COG2920	part of a sulfur-relay system
EHC70_08010	COG0670	Belongs to the BI1 family
EHC70_08015	COG1126	abc transporter atp-binding protein
EHC70_08020	COG0765	amino acid transport
EHC70_08025	COG4597	amino acid ABC transporter
EHC70_08030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC70_08050	COG1666	GTP binding
EHC70_08055	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC70_08075	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EHC70_08075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC70_08085	COG3008	intermembrane lipid transfer
EHC70_08090	COG2995	paraquat-inducible protein a
EHC70_08095	COG1132	(ABC) transporter
EHC70_08100	COG1956	GAF domain-containing protein
EHC70_08105	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EHC70_08120	COG0308	aminopeptidase N
EHC70_08130	COG2902	Dehydrogenase
EHC70_08135	COG0167	dihydroorotate dehydrogenase activity
EHC70_08150	COG0116	Belongs to the methyltransferase superfamily
EHC70_08150	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC70_08175	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC70_08180	COG1067	ATP-dependent peptidase activity
EHC70_08185	COG3120	sequence-specific DNA binding
EHC70_08235	COG4128	Pfam Zonular occludens toxin
EHC70_08315	COG2010	Cytochrome c
EHC70_08325	COG2217	Heavy metal translocating P-type atpase
EHC70_08340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC70_08345	COG0589	response to stress
EHC70_08355	COG0037	tRNA processing
EHC70_08375	COG3842	ATPase activity
EHC70_08380	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC70_08385	COG1177	transmembrane transport
EHC70_08390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC70_08395	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC70_08400	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EHC70_08410	COG0004	ammonium transporteR
EHC70_08435	COG0437	4 iron, 4 sulfur cluster binding
EHC70_08440	COG3383	formate dehydrogenase (NAD+) activity
EHC70_08440	COG0243	molybdopterin cofactor binding
EHC70_08450	COG3381	protein complex oligomerization
EHC70_08475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC70_08480	COG0488	(ABC) transporter
EHC70_08490	COG4191	Histidine kinase
EHC70_08495	COG2204	response regulator
EHC70_08515	COG3842	ATPase activity
EHC70_08520	COG0746	molybdenum cofactor guanylyltransferase activity
EHC70_08525	COG0303	'Molybdopterin
EHC70_08535	COG1940	carbohydrate kinase activity
EHC70_08575	COG0840	transmembrane signaling receptor activity
EHC70_08575	COG3290	protein histidine kinase activity
EHC70_08580	COG0791	NLP P60 protein
EHC70_08590	COG3706	GGDEF domain
EHC70_08595	COG2201	protein-glutamate methylesterase activity
EHC70_08610	COG0307	riboflavin synthase, alpha
EHC70_08615	COG0534	Mate efflux family protein
EHC70_08625	COG1793	dna ligase
EHC70_08660	COG2204	response regulator
EHC70_08705	COG0438	transferase activity, transferring glycosyl groups
EHC70_08710	COG1215	transferase activity, transferring glycosyl groups
EHC70_08715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC70_08725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC70_08740	COG1643	Atp-dependent helicase
EHC70_08745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHC70_08760	COG3302	dmso reductase anchor subunit
EHC70_08765	COG0437	4 iron, 4 sulfur cluster binding
EHC70_08770	COG0243	molybdopterin cofactor binding
EHC70_08810	COG0443	Heat shock 70 kDa protein
EHC70_08815	COG0443	Heat shock 70 kDa protein
EHC70_08845	COG1132	(ABC) transporter
EHC70_08850	COG1132	(ABC) transporter
EHC70_08875	COG0814	amino acid
EHC70_08890	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EHC70_08980	COG1522	sequence-specific DNA binding
EHC70_09015	COG0515	serine threonine protein kinase
EHC70_09040	COG3501	Rhs element vgr protein
EHC70_09055	COG2204	response regulator
EHC70_09080	COG0739	heme binding
EHC70_09090	COG0861	Integral membrane protein TerC family
EHC70_09100	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC70_09105	COG1328	CTP reductase activity
EHC70_09110	COG1280	lysine exporter protein (LysE YggA)
EHC70_09120	COG5001	Diguanylate cyclase
EHC70_09120	COG3300	MHYT domain
EHC70_09130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC70_09130	COG4191	Histidine kinase
EHC70_09135	COG0471	metal ion transport
EHC70_09170	COG0583	DNA-binding transcription factor activity
EHC70_09175	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC70_09235	COG0625	glutathione transferase activity
EHC70_09245	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EHC70_09260	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC70_09270	COG0601	transmembrane transport
EHC70_09275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC70_09280	COG0444	Belongs to the ABC transporter superfamily
EHC70_09300	COG3291	Pkd domain containing protein
EHC70_09315	COG1177	transmembrane transport
EHC70_09320	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC70_09325	COG3842	ATPase activity
EHC70_09330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC70_09335	COG2423	ornithine cyclodeaminase activity
EHC70_09355	COG3938	Belongs to the proline racemase family
EHC70_09385	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EHC70_09390	COG1451	nucleotide metabolic process
EHC70_09395	COG3475	LICD family
EHC70_09400	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EHC70_09405	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHC70_09425	COG0583	DNA-binding transcription factor activity
EHC70_09445	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EHC70_09450	COG4139	cobalamin transport
EHC70_09455	COG2988	succinylglutamate desuccinylase activity
EHC70_09480	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EHC70_09485	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EHC70_09490	COG0702	epimerase
EHC70_09500	COG2925	Exonuclease
EHC70_09505	COG1380	Effector of murein hydrolase LrgA
EHC70_09510	COG1346	cytolysis
EHC70_09515	COG0295	cytidine deaminase activity
EHC70_09520	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EHC70_09525	COG0500	methyltransferase
EHC70_09535	COG0776	regulation of translation
EHC70_09550	COG0072	phenylalanine-tRNA ligase activity
EHC70_09550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC70_09555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHC70_09560	COG3706	GGDEF domain
EHC70_09590	COG0393	Putative heavy-metal-binding
EHC70_09600	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EHC70_09610	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHC70_09625	COG2188	Transcriptional regulator
EHC70_09630	COG1228	amidohydrolase
EHC70_09635	COG0010	Belongs to the arginase family
EHC70_09640	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EHC70_09645	COG2986	histidine ammonia-lyase
EHC70_09660	COG0247	lactate metabolic process
EHC70_09660	COG0277	FAD linked oxidase domain protein
EHC70_09695	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EHC70_09710	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EHC70_09715	COG1643	Atp-dependent helicase
EHC70_09720	COG0281	malic enzyme
EHC70_09725	COG2949	membrane
EHC70_09730	COG0471	metal ion transport
EHC70_09755	COG0492	ferredoxin-NADP+ reductase activity
EHC70_09760	COG4988	ABC transporter
EHC70_09765	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EHC70_09770	COG3048	D-serine ammonia-lyase activity
EHC70_09775	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHC70_09785	COG4191	Histidine kinase
EHC70_09785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC70_09800	COG3070	regulator of competence-specific genes
EHC70_09820	COG2431	L-lysine efflux transmembrane transporter activity
EHC70_09830	COG0076	glutamate decarboxylase activity
EHC70_09835	COG1737	Transcriptional regulator
EHC70_09850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC70_09855	COG2985	domain, Protein
EHC70_09855	COG3273	potassium ion transport
EHC70_09860	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EHC70_09875	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC70_09890	COG4181	ATPase activity
EHC70_09895	COG0534	Mate efflux family protein
EHC70_09905	COG3005	denitrification pathway
EHC70_09935	COG2814	Major facilitator Superfamily
EHC70_09940	COG1187	pseudouridine synthase activity
EHC70_09945	COG1061	Type III restriction enzyme res subunit
EHC70_09955	COG0745	RESPONSE REGULATOR receiver
EHC70_09960	COG2205	protein histidine kinase activity
EHC70_09965	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EHC70_09995	COG3313	Fe-S protein
EHC70_10020	COG0493	'glutamate synthase
EHC70_10030	COG0398	Pfam SNARE associated Golgi protein
EHC70_10035	COG4134	Bacterial extracellular solute-binding protein
EHC70_10040	COG4135	transport system, permease component
EHC70_10045	COG4136	ATPase activity
EHC70_10050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHC70_10065	COG3604	Transcriptional regulator
EHC70_10070	COG1151	hydroxylamine reductase activity
EHC70_10075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC70_10085	COG0564	pseudouridine synthase activity
EHC70_10095	COG0733	neurotransmitter:sodium symporter activity
EHC70_10105	COG0626	cystathionine gamma-synthase activity
EHC70_10110	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EHC70_10115	COG5380	lipid catabolic process
EHC70_10120	COG2818	Glycosylase
EHC70_10135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC70_10140	COG1983	PspC domain protein
EHC70_10150	COG1842	Phage shock protein A
EHC70_10155	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EHC70_10165	COG4168	peptide transport system, permease
EHC70_10170	COG4171	peptide transport system, permease
EHC70_10180	COG4172	Belongs to the ABC transporter superfamily
EHC70_10190	COG1227	inorganic diphosphatase activity
EHC70_10205	COG0243	molybdopterin cofactor binding
EHC70_10210	COG3005	denitrification pathway
EHC70_10215	COG4459	periplasmic nitrate reductase
EHC70_10220	COG0390	transport system, permease component
EHC70_10230	COG2116	formate transmembrane transporter activity
EHC70_10255	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC70_10260	COG1435	thymidine kinase activity
EHC70_10265	COG0215	cysteine-tRNA ligase activity
EHC70_10270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC70_10275	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC70_10280	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC70_10290	COG3012	SEC-C Motif Domain Protein
EHC70_10295	COG0140	phosphoribosyl-ATP diphosphatase activity
EHC70_10295	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EHC70_10300	COG0107	imidazoleglycerol-phosphate synthase activity
EHC70_10305	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHC70_10310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHC70_10315	COG0131	Imidazoleglycerol-phosphate dehydratase
EHC70_10315	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC70_10320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHC70_10325	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHC70_10330	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EHC70_10345	COG1757	Na H antiporter
EHC70_10355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC70_10365	COG0482	sulfurtransferase activity
EHC70_10370	COG2915	High frequency lysogenization protein hflD homolog
EHC70_10375	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EHC70_10400	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EHC70_10415	COG0300	oxidoreductase activity
EHC70_10425	COG0501	Belongs to the peptidase M48B family
EHC70_10435	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EHC70_10445	COG0156	8-amino-7-oxononanoate synthase activity
EHC70_10450	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHC70_10455	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC70_10460	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC70_10475	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHC70_10480	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EHC70_10485	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EHC70_10490	COG1674	ftsk spoiiie
EHC70_10500	COG0686	Belongs to the AlaDH PNT family
EHC70_10510	COG0583	DNA-binding transcription factor activity
EHC70_10525	COG3568	Endonuclease Exonuclease Phosphatase
EHC70_10555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC70_10560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC70_10575	COG0840	transmembrane signaling receptor activity
EHC70_10690	COG0784	Response regulator, receiver
EHC70_10690	COG5002	protein histidine kinase activity
EHC70_10700	COG0754	glutathionylspermidine amidase activity
EHC70_10710	COG3766	membrane
EHC70_10720	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHC70_10725	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EHC70_10730	COG2885	chlorophyll binding
EHC70_10735	COG0823	Involved in the tonB-independent uptake of proteins
EHC70_10750	COG0811	peptide transport
EHC70_10755	COG0824	Thioesterase
EHC70_10765	COG4890	Cyd operon protein YbgT
EHC70_10770	COG1294	oxidase, subunit
EHC70_10775	COG1271	oxidase subunit
EHC70_10780	COG2255	four-way junction helicase activity
EHC70_10785	COG0632	four-way junction helicase activity
EHC70_10790	COG0840	transmembrane signaling receptor activity
EHC70_10795	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EHC70_10800	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EHC70_10805	COG1801	Protein of unknown function DUF72
EHC70_10810	COG4106	trans-aconitate 2-methyltransferase activity
EHC70_10815	COG0500	methyltransferase
EHC70_10825	COG0189	ligase activity
EHC70_10825	COG4067	protein conserved in archaea
EHC70_10845	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC70_10850	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EHC70_10855	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EHC70_10860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC70_10865	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC70_10870	COG0745	RESPONSE REGULATOR receiver
EHC70_10875	COG3381	protein complex oligomerization
EHC70_10880	COG1609	Transcriptional regulator
EHC70_10885	COG3070	regulator of competence-specific genes
EHC70_10905	COG0297	glycogen (starch) synthase activity
EHC70_10910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC70_10915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC70_10925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EHC70_10935	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EHC70_10940	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EHC70_10945	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHC70_10955	COG0542	response to heat
EHC70_10960	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EHC70_10965	COG1278	Cold shock
EHC70_10975	COG1187	pseudouridine synthase activity
EHC70_10980	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC70_10990	COG1199	ATP-dependent helicase activity
EHC70_10995	COG0730	response to heat
EHC70_11000	COG3923	Primosomal replication protein n
EHC70_11010	COG0708	Exodeoxyribonuclease III
EHC70_11025	COG4215	(ABC) transporter
EHC70_11055	COG1882	Formate acetyltransferase
EHC70_11065	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC70_11075	COG3013	Belongs to the UPF0304 family
EHC70_11085	COG2766	serine protein kinase
EHC70_11090	COG2718	Belongs to the UPF0229 family
EHC70_11095	COG2719	SpoVR family
EHC70_11100	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EHC70_11110	COG1663	tetraacyldisaccharide 4'-kinase activity
EHC70_11115	COG1132	(ABC) transporter
EHC70_11120	COG0658	competence protein
EHC70_11120	COG2333	competence protein COMEC
EHC70_11130	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC70_11135	COG1136	(ABC) transporter
EHC70_11140	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC70_11150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHC70_11165	COG1252	NADH dehydrogenase
EHC70_11175	COG3150	esterase
EHC70_11200	COG0537	adenosine 5'-monophosphoramidase activity
EHC70_11230	COG0516	GMP reductase activity
EHC70_11230	COG0517	IMP dehydrogenase activity
EHC70_11240	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EHC70_11245	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC70_11250	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC70_11260	COG2199	diguanylate cyclase activity
EHC70_11275	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EHC70_11280	COG1946	Acyl-CoA thioesterase
EHC70_11290	COG1522	sequence-specific DNA binding
EHC70_11320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC70_11370	COG0477	Major facilitator Superfamily
EHC70_11375	COG2855	membrane
EHC70_11390	COG1441	menaquinone biosynthetic process
EHC70_11395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EHC70_11400	COG0596	Alpha beta hydrolase
EHC70_11405	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EHC70_11410	COG1169	isochorismate synthase
EHC70_11415	COG0436	Aminotransferase
EHC70_11420	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EHC70_11425	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EHC70_11440	COG1555	photosystem II stabilization
EHC70_11445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC70_11450	COG0776	regulation of translation
EHC70_11455	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EHC70_11460	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHC70_11470	COG0544	peptidyl-prolyl cis-trans isomerase activity
EHC70_11480	COG2204	response regulator
EHC70_11490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EHC70_11495	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC70_11500	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EHC70_11505	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EHC70_11525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC70_11530	COG0569	domain protein
EHC70_11535	COG0513	Belongs to the DEAD box helicase family
EHC70_11540	COG1253	flavin adenine dinucleotide binding
EHC70_11575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC70_11580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC70_11595	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC70_11600	COG1216	Glycosyl transferase, family 2
EHC70_11605	COG2986	histidine ammonia-lyase
EHC70_11630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC70_11635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC70_11640	COG1028	Short-chain dehydrogenase reductase Sdr
EHC70_11660	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHC70_11665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC70_11670	COG0583	DNA-binding transcription factor activity
EHC70_11675	COG2951	lytic endotransglycosylase activity
EHC70_11680	COG3100	YcgL domain-containing protein
EHC70_11685	COG0850	regulation of cytokinetic process
EHC70_11690	COG2894	cell division
EHC70_11695	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EHC70_11700	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EHC70_11705	COG0318	PFAM AMP-dependent synthetase and ligase
EHC70_11710	COG2267	carboxylic ester hydrolase activity
EHC70_11725	COG1214	PFAM Peptidase M22, glycoprotease
EHC70_11730	COG1199	ATP-dependent helicase activity
EHC70_11735	COG0788	formyltetrahydrofolate deformylase activity
EHC70_11740	COG3102	Protein conserved in bacteria
EHC70_11750	COG0018	arginyl-trna synthetase
EHC70_11770	COG1918	ferrous iron import across plasma membrane
EHC70_11785	COG4977	sequence-specific DNA binding
EHC70_11790	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EHC70_11795	COG1121	(ABC) transporter
EHC70_11800	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC70_11810	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC70_11815	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHC70_11820	COG0567	Dehydrogenase, E1 component
EHC70_11825	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC70_11830	COG1053	succinate dehydrogenase
EHC70_11835	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EHC70_11840	COG2009	succinate dehydrogenase
EHC70_11850	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EHC70_11860	COG0033	Phosphoglucomutase
EHC70_11865	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EHC70_11870	COG0596	Alpha beta hydrolase
EHC70_11880	COG0716	FMN binding
EHC70_11890	COG0735	belongs to the Fur family
EHC70_11895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC70_11900	COG1263	PTS System
EHC70_11900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC70_11900	COG2190	(PTS) system
EHC70_11910	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHC70_11915	COG1846	Transcriptional regulator
EHC70_11915	COG1940	carbohydrate kinase activity
EHC70_11920	COG4651	solute:proton antiporter activity
EHC70_11920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EHC70_11925	COG0367	asparagine synthase
EHC70_11930	COG0250	Participates in transcription elongation, termination and antitermination
EHC70_11935	COG3104	oligopeptide transport
EHC70_11940	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EHC70_11945	COG0563	adenylate kinase activity
EHC70_11950	COG0326	Molecular chaperone. Has ATPase activity
EHC70_11955	COG3710	Transcriptional regulator
EHC70_11975	COG0622	Phosphoesterase
EHC70_12005	COG1090	epimerase
EHC70_12010	COG0300	oxidoreductase activity
EHC70_12020	COG3118	belongs to the thioredoxin family
EHC70_12025	COG0330	HflC and HflK could
EHC70_12050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHC70_12055	COG3115	cell septum assembly
EHC70_12060	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EHC70_12065	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EHC70_12075	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC70_12080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC70_12085	COG2190	(PTS) system
EHC70_12095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC70_12100	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC70_12110	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC70_12120	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC70_12130	COG1705	Flagellar rod assembly protein muramidase FlgJ
EHC70_12130	COG3951	Flagellar rod assembly protein muramidase FlgJ
EHC70_12135	COG1706	bacterial-type flagellum-dependent cell motility
EHC70_12140	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC70_12145	COG4786	Flagellar basal body rod
EHC70_12150	COG4787	bacterial-type flagellum-dependent cell motility
EHC70_12160	COG1749	Flagellar hook protein flgE
EHC70_12165	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC70_12170	COG1558	bacterial-type flagellum-dependent cell motility
EHC70_12175	COG1815	bacterial-type flagellum-dependent cell motility
EHC70_12180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EHC70_12185	COG0784	Response regulator, receiver
EHC70_12185	COG0835	chemotaxis
EHC70_12245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC70_12250	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC70_12265	COG2217	Heavy metal translocating P-type atpase
EHC70_12265	COG2608	mercury ion transmembrane transporter activity
EHC70_12305	COG2840	Smr protein MutS2
EHC70_12310	COG1187	pseudouridine synthase activity
EHC70_12320	COG0737	Belongs to the 5'-nucleotidase family
EHC70_12325	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EHC70_12330	COG2912	Transglutaminase-like superfamily
EHC70_12335	COG3094	Invasion gene expression up-regulator, SirB
EHC70_12340	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC70_12345	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHC70_12350	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHC70_12355	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EHC70_12360	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHC70_12365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHC70_12370	COG0193	aminoacyl-tRNA hydrolase activity
EHC70_12375	COG0012	GTP binding
EHC70_12490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC70_12500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHC70_12505	COG1702	phosphate starvation-inducible protein PhoH
EHC70_12510	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHC70_12515	COG4535	Mg2 and Co2 transporter CorC
EHC70_12520	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EHC70_12525	COG2888	peptidyl-tyrosine sulfation
EHC70_12530	COG0495	leucyl-tRNA aminoacylation
EHC70_12535	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EHC70_12540	COG1466	dna polymerase III delta subunit
EHC70_12545	COG0799	negative regulation of ribosome biogenesis
EHC70_12550	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHC70_12555	COG0768	penicillin binding
EHC70_12560	COG0772	Belongs to the SEDS family
EHC70_12565	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EHC70_12570	COG1686	Belongs to the peptidase S11 family
EHC70_12575	COG2921	Belongs to the UPF0250 family
EHC70_12580	COG0321	lipoyl(octanoyl) transferase activity
EHC70_12585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EHC70_12590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC70_12595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC70_12610	COG0366	Alpha amylase catalytic
EHC70_12625	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC70_12635	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHC70_12640	COG2011	ABC-type metal ion transport system permease component
EHC70_12645	COG1464	Belongs to the NlpA lipoprotein family
EHC70_12650	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
EHC70_12660	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC70_12660	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC70_12670	COG0745	RESPONSE REGULATOR receiver
EHC70_12670	COG3706	GGDEF domain
EHC70_12675	COG1611	Belongs to the LOG family
EHC70_12680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC70_12690	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EHC70_12695	COG2363	Small membrane protein
EHC70_12705	COG0583	DNA-binding transcription factor activity
EHC70_12710	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC70_12710	COG0301	tRNA thio-modification
EHC70_12715	COG2885	chlorophyll binding
EHC70_12720	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC70_12725	COG1722	exodeoxyribonuclease VII activity
EHC70_12730	COG0142	geranyltranstransferase activity
EHC70_12735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHC70_12740	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EHC70_12745	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EHC70_12750	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC70_12770	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC70_12770	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC70_12775	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHC70_12780	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHC70_12785	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHC70_12800	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EHC70_12805	COG2252	PERMEase
EHC70_12810	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC70_12835	COG0047	phosphoribosylformylglycinamidine synthase activity
EHC70_12835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHC70_12840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EHC70_12850	COG0590	tRNA wobble adenosine to inosine editing
EHC70_12855	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC70_12895	COG0484	heat shock protein binding
EHC70_12900	COG0443	Heat shock 70 kDa protein
EHC70_12910	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHC70_12915	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHC70_12925	COG0497	DNA recombination
EHC70_12930	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC70_12935	COG2914	Belongs to the UPF0125 (RnfH) family
EHC70_12940	COG2867	negative regulation of translational initiation
EHC70_12945	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHC70_12965	COG0583	DNA-binding transcription factor activity
EHC70_12970	COG3153	acetyltransferase
EHC70_12970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC70_12990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC70_12995	COG2873	o-acetylhomoserine
EHC70_13035	COG1115	amino acid carrier protein
EHC70_13045	COG1584	GPR1 FUN34 yaaH family protein
EHC70_13055	COG1757	Na H antiporter
EHC70_13060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EHC70_13060	COG0519	Catalyzes the synthesis of GMP from XMP
EHC70_13065	COG0516	GMP reductase activity
EHC70_13065	COG0517	IMP dehydrogenase activity
EHC70_13070	COG1570	exodeoxyribonuclease VII activity
EHC70_13085	COG1160	GTP binding
EHC70_13090	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC70_13095	COG2976	Protein conserved in bacteria
EHC70_13100	COG0124	histidyl-tRNA synthetase
EHC70_13105	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHC70_13120	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EHC70_13125	COG0105	UTP biosynthetic process
EHC70_13130	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC70_13135	COG2975	iron-sulfur cluster assembly
EHC70_13140	COG0633	Ferredoxin
EHC70_13145	COG0443	Heat shock 70 kDa protein
EHC70_13150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC70_13160	COG0822	iron-sulfur transferase activity
EHC70_13165	COG1104	cysteine desulfurase activity
EHC70_13180	COG0483	inositol monophosphate 1-phosphatase activity
EHC70_13190	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC70_13195	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC70_13200	COG1862	Preprotein translocase
EHC70_13205	COG0343	queuine tRNA-ribosyltransferase activity
EHC70_13210	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EHC70_13225	COG0517	IMP dehydrogenase activity
EHC70_13235	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EHC70_13245	COG0583	DNA-binding transcription factor activity
EHC70_13250	COG0450	alkyl hydroperoxide reductase
EHC70_13260	COG3142	Participates in the control of copper homeostasis
EHC70_13270	COG0704	Plays a role in the regulation of phosphate uptake
EHC70_13275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC70_13280	COG0581	inorganic phosphate transmembrane transporter activity
EHC70_13290	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EHC70_13295	COG0248	Ppx GppA phosphatase
EHC70_13305	COG5002	protein histidine kinase activity
EHC70_13310	COG0745	RESPONSE REGULATOR receiver
EHC70_13320	COG2974	May be involved in recombination
EHC70_13330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHC70_13390	COG0542	response to heat
EHC70_13400	COG0564	pseudouridine synthase activity
EHC70_13405	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC70_13410	COG0741	lytic transglycosylase activity
EHC70_13415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC70_13420	COG0077	Prephenate dehydratase
EHC70_13420	COG1605	Chorismate mutase
EHC70_13425	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EHC70_13430	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EHC70_13440	COG0488	(ABC) transporter
EHC70_13455	COG0739	heme binding
EHC70_13460	COG1605	Chorismate mutase
EHC70_13460	COG0287	Prephenate dehydrogenase
EHC70_13465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC70_13470	COG1472	Belongs to the glycosyl hydrolase 3 family
EHC70_13475	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EHC70_13480	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC70_13495	COG1966	Carbon starvation protein
EHC70_13500	COG3275	phosphorelay sensor kinase activity
EHC70_13505	COG3279	Response regulator of the LytR AlgR family
EHC70_13510	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHC70_13515	COG1047	Peptidyl-prolyl cis-trans
EHC70_13520	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHC70_13525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC70_13530	COG0196	riboflavin kinase activity
EHC70_13535	COG0728	peptidoglycan biosynthetic process
EHC70_13540	COG0268	Binds directly to 16S ribosomal RNA
EHC70_13550	COG0640	Transcriptional regulator
EHC70_13560	COG0583	DNA-binding transcription factor activity
EHC70_13565	COG1283	sodium-dependent phosphate transmembrane transporter activity
EHC70_13575	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHC70_13580	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHC70_13585	COG0730	response to heat
EHC70_13595	COG0494	nUDIX hydrolase
EHC70_13605	COG3066	DNA modification
EHC70_13615	COG0667	Aldo Keto reductase
EHC70_13630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EHC70_13640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EHC70_13645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC70_13655	COG0716	FMN binding
EHC70_13665	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EHC70_13670	COG0513	Belongs to the DEAD box helicase family
EHC70_13675	COG3022	response to hydroperoxide
EHC70_13680	COG1115	amino acid carrier protein
EHC70_13695	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EHC70_13705	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EHC70_13710	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EHC70_13715	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EHC70_13720	COG0083	homoserine kinase activity
EHC70_13735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC70_13750	COG0745	RESPONSE REGULATOR receiver
EHC70_13760	COG2198	Histidine kinase
EHC70_13760	COG5002	protein histidine kinase activity
EHC70_13760	COG0784	Response regulator, receiver
EHC70_13765	COG5001	Diguanylate cyclase
EHC70_13765	COG3706	GGDEF domain
EHC70_13765	COG4251	negative regulation of phosphorylation
EHC70_13765	COG2203	Gaf domain
EHC70_13770	COG1242	4 iron, 4 sulfur cluster binding
EHC70_13775	COG0070	glutamate synthase
EHC70_13775	COG0069	glutamate synthase activity
EHC70_13775	COG0067	glutamate synthase
EHC70_13785	COG0067	glutamate synthase
EHC70_13785	COG0070	glutamate synthase
EHC70_13785	COG0069	glutamate synthase activity
EHC70_13790	COG0493	'glutamate synthase
EHC70_13800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC70_13810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC70_13815	COG2860	membrane
EHC70_13820	COG0583	DNA-binding transcription factor activity
EHC70_13825	COG0730	response to heat
EHC70_13840	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EHC70_13845	COG0505	Belongs to the CarA family
EHC70_13850	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EHC70_13855	COG0494	nUDIX hydrolase
EHC70_13860	COG0653	protein targeting
EHC70_13870	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EHC70_13875	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHC70_13880	COG0849	cell division
EHC70_13885	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EHC70_13890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC70_13895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHC70_13900	COG0772	Belongs to the SEDS family
EHC70_13905	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHC70_13910	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHC70_13915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EHC70_13920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHC70_13925	COG0768	penicillin binding
EHC70_13930	COG3116	cell division
EHC70_13935	COG0275	rRNA processing
EHC70_13950	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHC70_13960	COG0792	nuclease activity
EHC70_13965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC70_13970	COG2823	Periplasmic or secreted lipoprotein
EHC70_13975	COG2969	positive regulation of protein catabolic process
EHC70_13980	COG0625	glutathione transferase activity
EHC70_13985	COG2857	Cytochrome c1
EHC70_13990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EHC70_13995	COG0723	plastoquinol--plastocyanin reductase activity
EHC70_14000	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EHC70_14005	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHC70_14015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EHC70_14025	COG3105	Protein conserved in bacteria
EHC70_14035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHC70_14040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHC70_14045	COG0187	DNA topoisomerase II activity
EHC70_14050	COG3150	esterase
EHC70_14060	COG3151	Protein conserved in bacteria
EHC70_14065	COG0494	nUDIX hydrolase
EHC70_14070	COG1538	Outer membrane efflux protein
EHC70_14075	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EHC70_14075	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EHC70_14080	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EHC70_14095	COG3025	triphosphatase activity
EHC70_14100	COG1392	Phosphate transport regulator
EHC70_14105	COG0306	phosphate transporter
EHC70_14110	COG4991	sh3 domain protein
EHC70_14120	COG3409	Peptidoglycan-binding domain 1 protein
EHC70_14120	COG3267	Type II secretory pathway component ExeA
EHC70_14125	COG0617	tRNA 3'-terminal CCA addition
EHC70_14130	COG1968	undecaprenyl-diphosphatase activity
EHC70_14135	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHC70_14140	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHC70_14145	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EHC70_14150	COG0596	Alpha beta hydrolase
EHC70_14155	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHC70_14160	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EHC70_14165	COG1610	YqeY-like protein
EHC70_14170	COG0358	DNA primase activity
EHC70_14175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHC70_14235	COG0582	viral genome integration into host DNA
EHC70_14320	COG0582	viral genome integration into host DNA
EHC70_14330	COG0326	Molecular chaperone. Has ATPase activity
EHC70_14345	COG2003	Belongs to the UPF0758 family
EHC70_14375	COG1464	Belongs to the NlpA lipoprotein family
EHC70_14410	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC70_14410	COG2213	PTS system mannitol-specific
EHC70_14415	COG0246	Mannitol dehydrogenase
EHC70_14420	COG3722	fumarate hydratase activity
EHC70_14435	COG1461	Dihydroxyacetone kinase
EHC70_14440	COG2376	Dihydroxyacetone kinase
EHC70_14450	COG5002	protein histidine kinase activity
EHC70_14465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EHC70_14470	COG1349	DNA-binding transcription factor activity
EHC70_14480	COG0469	pyruvate kinase activity
EHC70_14490	COG3706	GGDEF domain
EHC70_14495	COG0440	acetolactate synthase activity
EHC70_14500	COG0028	Belongs to the TPP enzyme family
EHC70_14505	COG1022	Amp-dependent synthetase and ligase
EHC70_14510	COG0583	DNA-binding transcription factor activity
EHC70_14530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHC70_14535	COG0473	3-isopropylmalate dehydrogenase activity
EHC70_14540	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHC70_14545	COG0066	3-isopropylmalate dehydratase activity
EHC70_14555	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC70_14560	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EHC70_14565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC70_14570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EHC70_14575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EHC70_14580	COG2967	ApaG domain
EHC70_14585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EHC70_14600	COG2966	Psort location CytoplasmicMembrane, score
EHC70_14605	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHC70_14615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EHC70_14620	COG0142	geranyltranstransferase activity
EHC70_14630	COG0039	L-malate dehydrogenase activity
EHC70_14665	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EHC70_14670	COG1178	ABC-type Fe3 transport system permease component
EHC70_14675	COG4143	(ABC) transporter
EHC70_14680	COG0163	prenyltransferase activity
EHC70_14685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC70_14695	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EHC70_14700	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EHC70_14710	COG2105	PFAM AIG2 family protein
EHC70_14720	COG0729	surface antigen
EHC70_14725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC70_14735	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC70_14750	COG4181	ATPase activity
EHC70_14770	COG0529	Catalyzes the synthesis of activated sulfate
EHC70_14775	COG0471	metal ion transport
EHC70_14775	COG3273	potassium ion transport
EHC70_14785	COG2895	sulfate adenylyltransferase (ATP) activity
EHC70_14790	COG0175	sulfate reduction
EHC70_14795	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHC70_14795	COG1648	precorrin-2 dehydrogenase activity
EHC70_14800	COG0737	Belongs to the 5'-nucleotidase family
EHC70_14810	COG0513	Belongs to the DEAD box helicase family
EHC70_14815	COG2153	protein acetylation
EHC70_14825	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC70_14835	COG0203	ribosomal protein L17
EHC70_14840	COG0202	RNA polymerase activity
EHC70_14850	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHC70_14855	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHC70_14865	COG0201	protein transport
EHC70_14870	COG0200	Binds to the 23S rRNA
EHC70_14875	COG1841	ribosomal large subunit assembly
EHC70_14890	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHC70_14895	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHC70_14900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHC70_14905	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHC70_14910	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHC70_14915	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHC70_14920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHC70_14925	COG0255	Belongs to the universal ribosomal protein uL29 family
EHC70_14935	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHC70_14940	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHC70_14945	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHC70_14950	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHC70_14960	COG0088	Forms part of the polypeptide exit tunnel
EHC70_14965	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHC70_14975	COG0254	rRNA binding
EHC70_14985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHC70_14990	COG1609	Transcriptional regulator
EHC70_15000	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EHC70_15005	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EHC70_15010	COG1575	Belongs to the MenA family. Type 1 subfamily
EHC70_15015	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC70_15020	COG3074	FtsZ-dependent cytokinesis
EHC70_15030	COG1494	fructose-1,6-bisphosphatase
EHC70_15055	COG0149	triose-phosphate isomerase activity
EHC70_15080	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC70_15090	COG0438	transferase activity, transferring glycosyl groups
EHC70_15115	COG0438	transferase activity, transferring glycosyl groups
EHC70_15175	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC70_15185	COG1560	Kdo2-lipid A biosynthetic process
EHC70_15190	COG0859	PFAM glycosyl transferase family 9
EHC70_15195	COG1519	Transferase
EHC70_15215	COG1028	Short-chain dehydrogenase reductase Sdr
EHC70_15225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHC70_15240	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC70_15250	COG2089	acid synthase
EHC70_15255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EHC70_15270	COG3642	lipopolysaccharide core region biosynthetic process
EHC70_15275	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC70_15280	COG0859	PFAM glycosyl transferase family 9
EHC70_15285	COG0463	Glycosyl transferase, family 2
EHC70_15300	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHC70_15305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EHC70_15315	COG2194	sulfuric ester hydrolase activity
EHC70_15325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EHC70_15330	COG2003	Belongs to the UPF0758 family
EHC70_15345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHC70_15350	COG1309	transcriptional regulator
EHC70_15355	COG1560	Kdo2-lipid A biosynthetic process
EHC70_15360	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EHC70_15365	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHC70_15370	COG1561	YicC-like family, N-terminal region
EHC70_15390	COG2003	Belongs to the UPF0758 family
EHC70_15440	COG0328	RNA-DNA hybrid ribonuclease activity
EHC70_15475	COG4608	Belongs to the ABC transporter superfamily
EHC70_15480	COG0444	Belongs to the ABC transporter superfamily
EHC70_15485	COG0747	negative chemotaxis
EHC70_15495	COG4174	ABC transporter (Permease)
EHC70_15520	COG0811	peptide transport
EHC70_15525	COG0848	biopolymer transport protein
EHC70_15540	COG0194	GDP metabolic process
EHC70_15545	COG1758	RNA polymerase activity
EHC70_15550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC70_15555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC70_15560	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHC70_15570	COG2233	PERMEase
EHC70_15575	COG2205	protein histidine kinase activity
EHC70_15580	COG0745	RESPONSE REGULATOR receiver
EHC70_15590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC70_15600	COG2183	response to ionizing radiation
EHC70_15610	COG0596	Alpha beta hydrolase
EHC70_15615	COG1040	competence protein
EHC70_15620	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EHC70_15620	COG0316	Belongs to the HesB IscA family
EHC70_15625	COG0494	nUDIX hydrolase
EHC70_15630	COG1218	3'(2'),5'-bisphosphate nucleotidase
EHC70_15640	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC70_15645	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC70_15650	COG3156	type II secretion system protein K
EHC70_15655	COG4795	General secretion pathway protein
EHC70_15660	COG2165	general secretion pathway protein
EHC70_15665	COG2165	general secretion pathway protein
EHC70_15670	COG2165	general secretion pathway protein
EHC70_15675	COG1459	type II secretion system
EHC70_15680	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC70_15690	COG3031	protein transport across the cell outer membrane
EHC70_15695	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EHC70_15700	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHC70_15705	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EHC70_15715	COG0456	acetyltransferase
EHC70_15720	COG1490	D-aminoacyl-tRNA deacylase activity
EHC70_15725	COG1295	ribonuclease BN
EHC70_15745	COG0174	glutamine synthetase
EHC70_15755	COG3852	Histidine kinase
EHC70_15760	COG2204	response regulator
EHC70_15770	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC70_15775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC70_15810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EHC70_15820	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC70_15820	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC70_15845	COG0084	hydrolase, TatD family'
EHC70_15855	COG0805	protein transport
EHC70_15865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHC70_15870	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC70_15875	COG3165	ubiquinone biosynthetic process from chorismate
EHC70_15880	COG2226	methyltransferase
EHC70_15885	COG1322	Protein conserved in bacteria
EHC70_15900	COG0628	permease
EHC70_15950	COG2823	Periplasmic or secreted lipoprotein
EHC70_15960	COG2081	HI0933 family
EHC70_15970	COG1528	Iron-storage protein
EHC70_15975	COG0589	response to stress
EHC70_15980	COG0697	spore germination
EHC70_15990	COG0742	ribosomal rna small subunit methyltransferase
EHC70_15995	COG5002	protein histidine kinase activity
EHC70_15995	COG5001	Diguanylate cyclase
EHC70_16000	COG1522	sequence-specific DNA binding
EHC70_16005	COG0339	signal peptide processing
EHC70_16015	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EHC70_16020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC70_16025	COG0583	DNA-binding transcription factor activity
EHC70_16030	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EHC70_16035	COG0800	Aldolase
EHC70_16040	COG2610	gluconate transmembrane transporter activity
EHC70_16045	COG3265	gluconokinase activity
EHC70_16050	COG0129	dihydroxy-acid dehydratase activity
EHC70_16055	COG2076	Multidrug Resistance protein
EHC70_16065	COG0583	DNA-binding transcription factor activity
EHC70_16070	COG1609	Transcriptional regulator
EHC70_16110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC70_16120	COG0747	negative chemotaxis
EHC70_16125	COG4172	Belongs to the ABC transporter superfamily
EHC70_16190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC70_16195	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC70_16205	COG2960	long-chain fatty acid transporting porin activity
EHC70_16210	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHC70_16215	COG0583	DNA-binding transcription factor activity
EHC70_16260	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EHC70_16270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHC70_16275	COG0408	coproporphyrinogen oxidase activity
EHC70_16280	COG0009	L-threonylcarbamoyladenylate synthase
EHC70_16285	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHC70_16290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EHC70_16295	COG0551	DNA topoisomerase type I activity
EHC70_16300	COG2922	Belongs to the Smg family
EHC70_16315	COG0242	peptide deformylase activity
EHC70_16320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHC70_16325	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC70_16325	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC70_16330	COG0569	domain protein
EHC70_16335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC70_16345	COG1272	protein, Hemolysin III
EHC70_16350	COG4326	sporulation control protein
EHC70_16360	COG3084	Protein conserved in bacteria
EHC70_16370	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EHC70_16375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC70_16380	COG0204	Acyl-transferase
EHC70_16475	COG0606	chelatase, subunit chli
EHC70_16485	COG3978	acetolactate synthase activity
EHC70_16490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EHC70_16495	COG0129	dihydroxy-acid dehydratase activity
EHC70_16505	COG0583	DNA-binding transcription factor activity
EHC70_16510	COG2814	Major facilitator Superfamily
EHC70_16515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC70_16520	COG0765	amino acid transport
EHC70_16525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHC70_16530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EHC70_16535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHC70_16540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHC70_16545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHC70_16550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHC70_16565	COG0356	it plays a direct role in the translocation of protons across the membrane
EHC70_16570	COG3312	ion transport
EHC70_16575	COG1475	DNA binding
EHC70_16580	COG1192	Involved in chromosome partitioning
EHC70_16585	COG0357	Ribosomal RNA small subunit methyltransferase G
EHC70_16590	COG0445	tRNA wobble uridine modification
EHC70_16595	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHC70_16600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHC70_16605	COG0706	membrane insertase activity
EHC70_16610	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EHC70_16615	COG0594	ribonuclease P activity
EHC70_16625	COG1126	abc transporter atp-binding protein
EHC70_16695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC70_16715	COG0745	RESPONSE REGULATOR receiver
EHC70_16750	COG0346	lactoylglutathione lyase activity
EHC70_16770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC70_16810	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC70_16825	COG2204	response regulator
EHC70_16850	COG1987	bacterial-type flagellum assembly
EHC70_16860	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHC70_16875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC70_16885	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHC70_16890	COG1516	flagellar protein fliS
EHC70_16905	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC70_16910	COG1191	sigma factor activity
EHC70_16915	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC70_16920	COG1360	Flagellar Motor Protein
EHC70_16955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC70_16960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC70_16970	COG0454	-acetyltransferase
EHC70_16980	COG2814	Major facilitator Superfamily
EHC70_17025	COG0628	permease
EHC70_17030	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC70_17040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC70_17050	COG4628	conserved protein (DUF2132)
EHC70_17055	COG0583	DNA-binding transcription factor activity
EHC70_17080	COG1686	Belongs to the peptidase S11 family
EHC70_17100	COG3397	chitin binding
EHC70_17105	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC70_17110	COG2095	MarC family integral membrane protein
EHC70_17130	COG0489	protein tyrosine kinase activity
EHC70_17130	COG3206	protein involved in exopolysaccharide biosynthesis
EHC70_17145	COG0583	DNA-binding transcription factor activity
EHC70_17155	COG1301	dicarboxylic acid transport
EHC70_17170	COG3339	Conserved Protein
EHC70_17175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC70_17180	COG0700	Nucleoside recognition
EHC70_17185	COG3366	ferrous iron transmembrane transporter activity
EHC70_17200	COG0366	Alpha amylase catalytic
EHC70_17205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC70_17210	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EHC70_17215	COG1640	4-alpha-glucanotransferase
EHC70_17220	COG0058	SHG alpha-glucan phosphorylase activity
EHC70_17235	COG2909	trisaccharide binding
EHC70_17250	COG1999	signal sequence binding
EHC70_17260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC70_17260	COG1263	PTS System
EHC70_17265	COG1162	GTPase activity
EHC70_17270	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EHC70_17280	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC70_17290	COG0531	amino acid
EHC70_17295	COG1982	Orn Lys Arg decarboxylase major
EHC70_17315	COG2356	endonuclease I
EHC70_17340	COG4580	involved in the transport of maltose and maltodextrins
EHC70_17365	COG0739	heme binding
EHC70_17375	COG0612	Peptidase, M16
EHC70_17380	COG0840	transmembrane signaling receptor activity
EHC70_17385	COG1120	ATPase activity
EHC70_17390	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC70_17395	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC70_17400	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC70_17405	COG4772	TonB-dependent receptor
EHC70_17430	COG4264	IucA IucC family
EHC70_17435	COG0019	diaminopimelate decarboxylase activity
EHC70_17440	COG1653	transport
EHC70_17450	COG0745	RESPONSE REGULATOR receiver
EHC70_17475	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC70_17480	COG1129	ABC transporter
EHC70_17485	COG1879	ABC-type sugar transport system periplasmic component
EHC70_17490	COG1069	ribulokinase activity
EHC70_17500	COG2160	L-arabinose isomerase activity
EHC70_17525	COG1764	response to oxidative stress
EHC70_17530	COG1846	Transcriptional regulator
EHC70_17535	COG0450	alkyl hydroperoxide reductase
EHC70_17540	COG3634	alkyl hydroperoxide reductase activity
EHC70_17590	COG0840	transmembrane signaling receptor activity
EHC70_17595	COG0583	DNA-binding transcription factor activity
EHC70_17600	COG1486	melibiose metabolic process
EHC70_17615	COG2258	MOSC domain
EHC70_17620	COG0513	Belongs to the DEAD box helicase family
EHC70_17630	COG2186	Transcriptional regulator
EHC70_17640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC70_17650	COG0246	Mannitol dehydrogenase
EHC70_17655	COG1904	glucuronate isomerase
EHC70_17660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC70_17665	COG0800	Aldolase
EHC70_17690	COG2207	Transcriptional regulator
EHC70_17700	COG1132	(ABC) transporter
EHC70_17745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC70_17775	COG0259	pyridoxamine-phosphate oxidase activity
EHC70_17820	COG4166	transmembrane transport
EHC70_17840	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC70_17845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC70_17845	COG1263	PTS System
EHC70_17850	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC70_17855	COG3340	Belongs to the peptidase S51 family
EHC70_17875	COG1444	tRNA N-acetyltransferase activity
EHC70_17900	COG4608	Belongs to the ABC transporter superfamily
EHC70_17915	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EHC70_17915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC70_17940	COG0217	transcriptional regulatory protein
EHC70_17945	COG0772	Belongs to the SEDS family
EHC70_17980	COG3275	phosphorelay sensor kinase activity
EHC70_17985	COG3279	Response regulator of the LytR AlgR family
EHC70_17995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC70_18030	COG0786	glutamate:sodium symporter activity
EHC70_18040	COG1131	(ABC) transporter
EHC70_18045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC70_18050	COG0786	glutamate:sodium symporter activity
EHC70_18065	COG0363	glucosamine-6-phosphate deaminase activity
EHC70_18085	COG1741	Belongs to the pirin family
EHC70_18090	COG2259	Doxx family
EHC70_18105	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EHC70_18110	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHC70_18120	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC70_18160	COG3123	guanosine phosphorylase activity
EHC70_18170	COG5001	Diguanylate cyclase
EHC70_18180	COG0534	Mate efflux family protein
EHC70_18185	COG0564	pseudouridine synthase activity
EHC70_18200	COG0583	DNA-binding transcription factor activity
EHC70_18205	COG0561	phosphatase activity
EHC70_18215	COG2199	diguanylate cyclase activity
EHC70_18230	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EHC70_18235	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EHC70_18240	COG0583	DNA-binding transcription factor activity
EHC70_18255	COG1414	Transcriptional regulator
EHC70_18260	COG1028	Short-chain dehydrogenase reductase Sdr
EHC70_18270	COG1917	Cupin 2, conserved barrel domain protein
EHC70_18285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC70_18290	COG0800	Aldolase
EHC70_18310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC70_18315	COG0823	Involved in the tonB-independent uptake of proteins
EHC70_18320	COG2375	cellular response to nickel ion
EHC70_18350	COG1357	PFAM Pentapeptide repeats (8 copies)
EHC70_18355	COG3047	cAMP biosynthetic process
EHC70_18385	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EHC70_18385	COG3408	Glycogen debranching enzyme
EHC70_18390	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EHC70_18400	COG0583	DNA-binding transcription factor activity
EHC70_18410	COG0583	DNA-binding transcription factor activity
EHC70_18425	COG0546	phosphoglycolate phosphatase activity
EHC70_18450	COG3835	regulator
EHC70_18455	COG2610	gluconate transmembrane transporter activity
EHC70_18460	COG1929	Belongs to the glycerate kinase type-1 family
EHC70_18465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC70_18500	COG1028	Short-chain dehydrogenase reductase Sdr
EHC70_18510	COG3005	denitrification pathway
EHC70_18515	COG0243	molybdopterin cofactor binding
EHC70_18525	COG0352	thiamine-phosphate diphosphorylase activity
EHC70_18530	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHC70_18535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EHC70_18540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC70_18545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC70_18550	COG1116	anion transmembrane transporter activity
EHC70_18555	COG0351	phosphomethylpyrimidine kinase
EHC70_18565	COG0312	modulator of DNA gyrase
EHC70_18570	COG0312	modulator of DNA gyrase
EHC70_18575	COG1901	pseudouridine methyltransferase
EHC70_18640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC70_18650	COG0584	glycerophosphoryl diester phosphodiesterase
EHC70_18660	COG0745	RESPONSE REGULATOR receiver
EHC70_18680	COG0811	peptide transport
EHC70_18685	COG0811	peptide transport
EHC70_18690	COG0848	biopolymer transport protein
EHC70_18735	COG0803	Belongs to the bacterial solute-binding protein 9 family
EHC70_18740	COG1121	(ABC) transporter
EHC70_18745	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC70_18760	COG1770	oligopeptidase
EHC70_18765	COG2814	Major facilitator Superfamily
EHC70_18770	COG0010	Belongs to the arginase family
EHC70_18775	COG1166	arginine decarboxylase activity
EHC70_18785	COG4067	protein conserved in archaea
EHC70_18785	COG0189	ligase activity
EHC70_18790	COG0189	ligase activity
EHC70_18795	COG0583	DNA-binding transcription factor activity
EHC70_18845	COG3706	GGDEF domain
EHC70_18875	COG0579	oxidoreductase
EHC70_18885	COG3033	Beta-eliminating lyase
EHC70_18905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC70_18920	COG3706	GGDEF domain
EHC70_18925	COG0840	transmembrane signaling receptor activity
EHC70_18940	COG3706	GGDEF domain
EHC70_18945	COG0415	Belongs to the DNA photolyase family
EHC70_18950	COG3046	protein related to deoxyribodipyrimidine photolyase
EHC70_18965	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC70_18965	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC70_18970	COG1765	OsmC-like protein
EHC70_18975	COG0110	maltose O-acetyltransferase activity
EHC70_19015	COG1011	Hydrolase
EHC70_19030	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC70_19040	COG2067	long-chain fatty acid transport protein
EHC70_19045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC70_19050	COG0577	efflux transmembrane transporter activity
EHC70_19050	COG1136	(ABC) transporter
EHC70_19060	COG3240	lipase activity
EHC70_19085	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC70_19090	COG1609	Transcriptional regulator
EHC70_19095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC70_19110	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC70_19120	COG3842	ATPase activity
EHC70_19145	COG2990	Protein conserved in bacteria
EHC70_19155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC70_19160	COG2866	Carboxypeptidase
EHC70_19175	COG0583	DNA-binding transcription factor activity
EHC70_19200	COG1760	l-serine dehydratase
EHC70_19220	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC70_19225	COG0741	lytic transglycosylase activity
EHC70_19245	COG1815	bacterial-type flagellum-dependent cell motility
EHC70_19250	COG1558	bacterial-type flagellum-dependent cell motility
EHC70_19255	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC70_19260	COG1749	Flagellar hook protein flgE
EHC70_19265	COG4787	bacterial-type flagellum-dependent cell motility
EHC70_19270	COG4786	Flagellar basal body rod
EHC70_19275	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC70_19280	COG1706	bacterial-type flagellum-dependent cell motility
EHC70_19290	COG1256	bacterial-type flagellum assembly
EHC70_19290	COG4786	Flagellar basal body rod
EHC70_19295	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC70_19315	COG1304	FMN binding
EHC70_19345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC70_19350	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC70_19355	COG0459	protein refolding
EHC70_19370	COG1280	lysine exporter protein (LysE YggA)
EHC70_19390	COG1309	transcriptional regulator
EHC70_19400	COG0737	Belongs to the 5'-nucleotidase family
EHC70_19405	COG2070	2-Nitropropane dioxygenase
EHC70_19410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC70_19420	COG0583	DNA-binding transcription factor activity
EHC70_19435	COG0346	lactoylglutathione lyase activity
EHC70_19440	COG1349	DNA-binding transcription factor activity
EHC70_19450	COG0753	catalase activity
EHC70_19460	COG1335	isochorismatase
EHC70_19470	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EHC70_19495	COG0583	DNA-binding transcription factor activity
EHC70_19510	COG3713	MltA-interacting MipA family protein
EHC70_19520	COG3015	lipoprotein NlpE involved in copper resistance
EHC70_19530	COG1342	Belongs to the UPF0251 family
EHC70_19555	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC70_19565	COG4948	Mandelate Racemase Muconate Lactonizing
EHC70_19575	COG0583	DNA-binding transcription factor activity
EHC70_19625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC70_19675	COG3842	ATPase activity
EHC70_19705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC70_19725	COG3706	GGDEF domain
EHC70_19745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC70_19760	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC70_19765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC70_19785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC70_19785	COG0574	Belongs to the PEP-utilizing enzyme family
EHC70_19790	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EHC70_19795	COG0252	asparaginase activity
EHC70_19805	COG0583	DNA-binding transcription factor activity
EHC70_19820	COG3122	Protein conserved in bacteria
EHC70_19835	COG1028	Short-chain dehydrogenase reductase Sdr
EHC70_19845	COG1063	alcohol dehydrogenase
EHC70_19850	COG1902	pentaerythritol trinitrate reductase activity
EHC70_19865	COG0583	DNA-binding transcription factor activity
EHC70_19875	COG0513	Belongs to the DEAD box helicase family
EHC70_19920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC70_19925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC70_19925	COG2207	Transcriptional regulator
EHC70_19955	COG2354	Protein conserved in bacteria
EHC70_19960	COG0418	dihydroorotase activity
EHC70_19970	COG0401	homolog of Blt101
EHC70_19980	COG0633	Ferredoxin
EHC70_19980	COG0633	Ferredoxin
EHC70_19980	COG3217	Mosc domain protein beta barrel domain protein
EHC70_19980	COG3217	Mosc domain protein beta barrel domain protein
EHC70_19985	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EHC70_19990	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHC70_20035	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EHC70_20040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC70_20050	COG0848	biopolymer transport protein
EHC70_20055	COG0811	peptide transport
EHC70_20060	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EHC70_20070	COG3721	Heme iron utilization protein
EHC70_20075	COG0748	coenzyme F420 binding
EHC70_20085	COG0784	Response regulator, receiver
EHC70_20085	COG0835	chemotaxis
EHC70_20095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC70_20105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC70_20105	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EHC70_20130	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC70_20135	COG0783	Belongs to the Dps family
EHC70_20145	COG0583	DNA-binding transcription factor activity
EHC70_20180	COG4934	collagen metabolic process
EHC70_20190	COG0366	Alpha amylase catalytic
EHC70_20210	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC70_20215	COG0589	response to stress
EHC70_20220	COG0488	(ABC) transporter
EHC70_20225	COG1505	serine-type exopeptidase activity
EHC70_20235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC70_20245	COG2067	long-chain fatty acid transport protein
EHC70_20255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC70_20265	COG2203	Gaf domain
EHC70_20265	COG2199	diguanylate cyclase activity
EHC70_20285	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC70_20310	COG3383	formate dehydrogenase (NAD+) activity
EHC70_20325	COG0842	Transport permease protein
EHC70_20330	COG1131	(ABC) transporter
EHC70_20340	COG0840	transmembrane signaling receptor activity
EHC70_20350	COG2706	6-phosphogluconolactonase activity
EHC70_20360	COG1881	PFAM PEBP family protein
EHC70_20370	COG0798	PFAM Bile acid sodium symporter
EHC70_20390	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC70_20395	COG2213	PTS system mannitol-specific
EHC70_20400	COG1063	alcohol dehydrogenase
EHC70_20410	COG1072	(Pantothenic acid kinase))
EHC70_20415	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC70_20435	COG0814	amino acid
EHC70_20475	COG0739	heme binding
EHC70_20480	COG5001	Diguanylate cyclase
EHC70_20485	COG0583	DNA-binding transcription factor activity
EHC70_20490	COG2814	Major facilitator Superfamily
EHC70_20515	COG0697	spore germination
EHC70_20545	COG2207	Transcriptional regulator
EHC70_20550	COG1280	lysine exporter protein (LysE YggA)
EHC70_20560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC70_20565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC70_20575	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EHC70_20600	COG1612	heme a metabolic process
EHC70_20605	COG0109	protoheme IX farnesyltransferase activity
EHC70_20610	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC70_20645	COG1278	Cold shock
EHC70_20650	COG3036	rescue of stalled ribosome
EHC70_20665	COG2199	diguanylate cyclase activity
EHC70_20685	COG1136	(ABC) transporter
EHC70_20685	COG0577	efflux transmembrane transporter activity
EHC70_20695	COG0840	transmembrane signaling receptor activity
EHC70_20705	COG0783	Belongs to the Dps family
EHC70_20715	COG2133	pyrroloquinoline quinone binding
EHC70_20720	COG1454	alcohol dehydrogenase
EHC70_20725	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EHC70_20765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC70_20770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC70_20775	COG3186	Phenylalanine-4-hydroxylase
EHC70_20780	COG2154	pterin-4-alpha-carbinolamine dehydratase
EHC70_20805	COG3530	Putative quorum-sensing-regulated virulence factor
EHC70_20810	COG0513	Belongs to the DEAD box helicase family
EHC70_20815	COG4628	conserved protein (DUF2132)
EHC70_20820	COG0133	tryptophan synthase activity
EHC70_20830	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EHC70_20840	COG0523	cobalamin synthesis protein
EHC70_20845	COG0513	Belongs to the DEAD box helicase family
EHC70_20865	COG2200	EAL domain
EHC70_20870	COG1119	ATPase activity
EHC70_20875	COG0840	transmembrane signaling receptor activity
EHC70_20900	COG0641	radical SAM
EHC70_20935	COG0582	viral genome integration into host DNA
EHC70_20980	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC70_20995	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EHC70_21000	COG0513	Belongs to the DEAD box helicase family
EHC70_21005	COG5001	Diguanylate cyclase
EHC70_21015	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC70_21030	COG5413	integral membrane protein
EHC70_21040	COG1024	Enoyl-CoA hydratase
EHC70_21045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHC70_21050	COG1960	acyl-CoA dehydrogenase activity
EHC70_21060	COG0183	Belongs to the thiolase family
EHC70_21080	COG1024	Enoyl-CoA hydratase
EHC70_21090	COG1028	Short-chain dehydrogenase reductase Sdr
EHC70_21095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC70_21100	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHC70_21105	COG1845	cytochrome c oxidase, subunit III
EHC70_21110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EHC70_21115	COG0109	protoheme IX farnesyltransferase activity
EHC70_21130	COG1902	pentaerythritol trinitrate reductase activity
EHC70_21140	COG1126	abc transporter atp-binding protein
EHC70_21145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC70_21150	COG4215	(ABC) transporter
EHC70_21155	COG4160	amino acid transport
EHC70_21170	COG0625	glutathione transferase activity
EHC70_21210	COG0443	Heat shock 70 kDa protein
EHC70_21215	COG2847	Copper chaperone PCu(A)C
EHC70_21240	COG4607	ABC-type enterochelin transport system periplasmic component
EHC70_21245	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC70_21250	COG4605	iron ion homeostasis
EHC70_21255	COG4604	ABC transporter, ATP-binding protein
EHC70_21260	COG0789	Transcriptional regulator
EHC70_21275	COG4771	TonB-dependent receptor
EHC70_21275	COG1629	transport
EHC70_21310	COG1289	transmembrane transporter activity
EHC70_21315	COG0210	DNA helicase
EHC70_21320	COG1803	Methylglyoxal synthase
EHC70_21325	COG1879	ABC-type sugar transport system periplasmic component
EHC70_21330	COG2205	protein histidine kinase activity
EHC70_21330	COG0784	Response regulator, receiver
EHC70_21330	COG2198	Histidine kinase
EHC70_21345	COG0745	RESPONSE REGULATOR receiver
EHC70_21350	COG3119	arylsulfatase activity
EHC70_21355	COG3119	arylsulfatase activity
EHC70_21370	COG3119	arylsulfatase activity
EHC70_21375	COG0641	radical SAM
EHC70_21380	COG0714	Associated with various cellular activities
EHC70_21410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC70_21415	COG0583	DNA-binding transcription factor activity
EHC70_21420	COG1597	lipid kinase activity
EHC70_21425	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC70_21445	COG0641	radical SAM
EHC70_21475	COG0501	Belongs to the peptidase M48B family
EHC70_21480	COG1704	LemA family
EHC70_21485	COG3069	C4-dicarboxylate transmembrane transporter activity
EHC70_21495	COG1214	PFAM Peptidase M22, glycoprotease
EHC70_21495	COG0456	acetyltransferase
EHC70_21515	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EHC70_21535	COG2207	Transcriptional regulator
EHC70_21560	COG4964	Belongs to the GSP D family
EHC70_21620	COG0583	DNA-binding transcription factor activity
EHC70_21625	COG0583	DNA-binding transcription factor activity
EHC70_21640	COG3300	MHYT domain
EHC70_21640	COG5001	Diguanylate cyclase
EHC70_21645	COG2197	response regulator
EHC70_21650	COG3706	GGDEF domain
EHC70_21660	COG2197	response regulator
EHC70_21685	COG0835	chemotaxis
EHC70_21685	COG0784	Response regulator, receiver
EHC70_21705	COG2962	Rard protein
EHC70_21720	COG0671	phosphoesterase, PA-phosphatase related
EHC70_21735	COG2076	Multidrug Resistance protein
EHC70_21765	COG0471	metal ion transport
EHC70_21770	COG3290	protein histidine kinase activity
EHC70_21775	COG4565	transcriptional regulatory protein
EHC70_21785	COG0069	glutamate synthase activity
EHC70_21785	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC70_21795	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC70_21820	COG1902	pentaerythritol trinitrate reductase activity
EHC70_21825	COG0346	lactoylglutathione lyase activity
EHC70_21845	COG2239	Acts as a magnesium transporter
EHC70_21875	COG0242	peptide deformylase activity
EHC70_21925	COG2176	DNA-directed DNA polymerase activity
EHC70_21930	COG0583	DNA-binding transcription factor activity
EHC70_21935	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC70_21975	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC70_21975	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC70_21980	COG0509	glycine decarboxylation via glycine cleavage system
EHC70_21985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC70_22025	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EHC70_22025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC70_22025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC70_22030	COG1105	Belongs to the carbohydrate kinase PfkB family
EHC70_22035	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC70_22035	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC70_22040	COG1609	Transcriptional regulator
EHC70_22060	COG2200	EAL domain
EHC70_22060	COG2203	Gaf domain
EHC70_22060	COG2199	diguanylate cyclase activity
EHC70_22065	COG0765	amino acid transport
EHC70_22070	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC70_22075	COG0765	amino acid transport
EHC70_22080	COG1126	abc transporter atp-binding protein
EHC70_22085	COG0469	pyruvate kinase activity
EHC70_22090	COG2271	Major facilitator Superfamily
EHC70_22095	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC70_22115	COG1979	alcohol dehydrogenase
EHC70_22120	COG2207	Transcriptional regulator
EHC70_22135	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC70_22140	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EHC70_22145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC70_22165	COG3437	response regulator, receiver
EHC70_22165	COG0784	Response regulator, receiver
EHC70_22175	COG0546	phosphoglycolate phosphatase activity
EHC70_22185	COG0840	transmembrane signaling receptor activity
EHC70_22195	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EHC70_22200	COG0513	Belongs to the DEAD box helicase family
EHC70_22205	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EHC70_22220	COG3038	cytochrome b561
EHC70_22225	COG2353	YceI-like domain
EHC70_22230	COG2116	formate transmembrane transporter activity
EHC70_22235	COG0583	DNA-binding transcription factor activity
EHC70_22245	COG3593	DNA synthesis involved in DNA repair
EHC70_22250	COG0737	Belongs to the 5'-nucleotidase family
EHC70_22255	COG0861	Integral membrane protein TerC family
EHC70_22270	COG2267	carboxylic ester hydrolase activity
EHC70_22275	COG2067	long-chain fatty acid transport protein
EHC70_22290	COG2050	protein possibly involved in aromatic compounds catabolism
EHC70_22300	COG4533	DNA binding
EHC70_22325	COG0484	heat shock protein binding
EHC70_22335	COG3300	MHYT domain
EHC70_22335	COG5001	Diguanylate cyclase
EHC70_22340	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EHC70_22350	COG4181	ATPase activity
EHC70_22355	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EHC70_22360	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EHC70_22360	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC70_22365	COG1984	allophanate hydrolase subunit 2
EHC70_22370	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EHC70_22375	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EHC70_22380	COG5001	Diguanylate cyclase
EHC70_22380	COG5002	protein histidine kinase activity
EHC70_22380	COG3447	MASE1 domain protein
EHC70_22385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHC70_22395	COG1629	transport
EHC70_22395	COG4771	TonB-dependent receptor
EHC70_22400	COG0583	DNA-binding transcription factor activity
EHC70_22405	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC70_22405	COG1042	CoA-binding domain protein
EHC70_22405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC70_22415	COG1181	Belongs to the D-alanine--D-alanine ligase family
EHC70_22425	COG0023	Translation Initiation Factor
EHC70_22445	COG0583	DNA-binding transcription factor activity
EHC70_22455	COG0589	response to stress
EHC70_22460	COG3140	Belongs to the UPF0181 family
EHC70_22485	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EHC70_22490	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EHC70_22505	COG0745	RESPONSE REGULATOR receiver
EHC70_22505	COG3706	GGDEF domain
EHC70_22515	COG4251	negative regulation of phosphorylation
EHC70_22515	COG5001	Diguanylate cyclase
EHC70_22515	COG2203	Gaf domain
EHC70_22515	COG3706	GGDEF domain
EHC70_22525	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EHC70_22530	COG4149	molybdate abc transporter
EHC70_22535	COG0725	ABC transporter, periplasmic molybdate-binding protein
EHC70_22540	COG1492	cobalamin metabolic process
EHC70_22545	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC70_22555	COG4067	protein conserved in archaea
EHC70_22555	COG0189	ligase activity
EHC70_22575	COG0534	Mate efflux family protein
EHC70_22580	COG0602	queuosine metabolic process
EHC70_22585	COG1328	CTP reductase activity
EHC70_22600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC70_22625	COG0446	pyridine nucleotide-disulphide oxidoreductase
EHC70_22630	COG0243	molybdopterin cofactor binding
EHC70_22640	COG0583	DNA-binding transcription factor activity
EHC70_22645	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC70_22655	COG2197	response regulator
EHC70_22660	COG3851	Histidine kinase
EHC70_22665	COG2271	Major facilitator Superfamily
EHC70_22690	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC70_22695	COG3118	belongs to the thioredoxin family
EHC70_22700	COG2814	Major facilitator Superfamily
EHC70_22710	COG0534	Mate efflux family protein
EHC70_22745	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC70_22765	COG2116	formate transmembrane transporter activity
EHC70_22770	COG2146	nitrite reductase [NAD(P)H] activity
EHC70_22775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC70_22780	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC70_22825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC70_22825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC70_22870	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC70_22890	COG0277	FAD linked oxidase domain protein
EHC70_22895	COG0583	DNA-binding transcription factor activity
EHC70_22915	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EHC70_22930	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EHC70_22945	COG1288	antiporter activity
EHC70_22955	COG2814	Major facilitator Superfamily
EHC70_22965	COG3040	lipid binding
EHC70_22985	COG0419	ATPase involved in DNA repair
EHC70_22990	COG0420	3'-5' exonuclease activity
EHC70_23005	COG3501	Rhs element vgr protein
EHC70_23060	COG0631	protein serine/threonine phosphatase activity
EHC70_23105	COG0515	serine threonine protein kinase
EHC70_23105	COG2815	serine threonine protein kinase
EHC70_23160	COG2146	nitrite reductase [NAD(P)H] activity
EHC70_23160	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC70_23165	COG1116	anion transmembrane transporter activity
EHC70_23170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC70_23175	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC70_23185	COG3707	response regulator
EHC70_23205	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHC70_23205	COG1648	precorrin-2 dehydrogenase activity
EHC70_23210	COG0243	molybdopterin cofactor binding
EHC70_23215	COG0456	acetyltransferase
EHC70_23220	COG0814	amino acid
EHC70_23230	COG0745	RESPONSE REGULATOR receiver
EHC70_23230	COG3706	GGDEF domain
EHC70_23250	COG1785	Belongs to the alkaline phosphatase family
EHC70_23265	COG0745	RESPONSE REGULATOR receiver
EHC70_23285	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EHC70_23300	COG1609	Transcriptional regulator
EHC70_23305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC70_23310	COG1879	ABC-type sugar transport system periplasmic component
EHC70_23315	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC70_23320	COG1129	ABC transporter
EHC70_23325	COG1869	D-ribose catabolic process
EHC70_23330	COG5001	Diguanylate cyclase
EHC70_23335	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC70_23395	COG0784	Response regulator, receiver
EHC70_23395	COG2205	protein histidine kinase activity
EHC70_23415	COG5001	Diguanylate cyclase
EHC70_23415	COG3300	MHYT domain
EHC70_23425	COG0330	HflC and HflK could
EHC70_23440	COG0517	IMP dehydrogenase activity
EHC70_23440	COG4175	Glycine betaine
EHC70_23445	COG4176	ABC-type proline glycine betaine transport system permease component
EHC70_23460	COG1012	belongs to the aldehyde dehydrogenase family
EHC70_23465	COG1309	transcriptional regulator
EHC70_23470	COG3706	GGDEF domain
EHC70_23495	COG1024	Enoyl-CoA hydratase
EHC70_23500	COG1960	acyl-CoA dehydrogenase activity
EHC70_23510	COG0183	Belongs to the thiolase family
EHC70_23520	COG1960	acyl-CoA dehydrogenase activity
EHC70_23525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHC70_23545	COG2205	protein histidine kinase activity
EHC70_23545	COG3437	response regulator, receiver
EHC70_23545	COG3850	Histidine kinase
EHC70_23545	COG4999	Histidine kinase
EHC70_23560	COG3264	Mechanosensitive ion channel
EHC70_23560	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC70_23570	COG0110	maltose O-acetyltransferase activity
EHC70_23575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC70_23580	COG1271	oxidase subunit
EHC70_23585	COG1294	oxidase, subunit
EHC70_23595	COG0384	phenazine biosynthesis protein PhzF
EHC70_23600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHC70_23605	COG0789	Transcriptional regulator
EHC70_23615	COG3474	cytochrome
EHC70_23625	COG0500	methyltransferase
EHC70_23685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC70_23810	COG2356	endonuclease I
EHC70_23895	COG0583	DNA-binding transcription factor activity
EHC70_23905	COG1683	Conserved Protein
EHC70_23925	COG2026	Addiction module toxin, RelE StbE family
EHC70_23930	COG4115	mRNA cleavage
EHC70_23935	COG2161	toxin-antitoxin pair type II binding
EHC70_23955	COG0494	nUDIX hydrolase
EHC70_23985	COG1012	belongs to the aldehyde dehydrogenase family
EHC70_23995	COG2202	Pas domain
EHC70_23995	COG2199	diguanylate cyclase activity
EHC70_23995	COG2200	EAL domain
EHC70_24020	COG0840	transmembrane signaling receptor activity
EHC70_24050	COG0840	transmembrane signaling receptor activity
EHC70_24105	COG0464	growth
EHC70_24110	COG4974	Belongs to the 'phage' integrase family
EHC70_24115	COG0516	GMP reductase activity
EHC70_24120	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EHC70_24120	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHC70_24135	COG4989	oxidoreductase activity
EHC70_24150	COG0038	chloride channel
EHC70_24160	COG1914	H( )-stimulated, divalent metal cation uptake system
EHC70_24165	COG0302	gtp cyclohydrolase
EHC70_24175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC70_24195	COG2897	thiosulfate sulfurtransferase activity
EHC70_24225	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC70_24230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC70_24235	COG0840	transmembrane signaling receptor activity
EHC70_24245	COG2814	Major facilitator Superfamily
EHC70_24250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC70_24265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC70_24275	COG0840	transmembrane signaling receptor activity
EHC70_24295	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC70_24310	COG2197	response regulator
EHC70_24315	COG3850	Histidine kinase
EHC70_24320	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHC70_24330	COG0243	molybdopterin cofactor binding
EHC70_24340	COG3005	denitrification pathway
EHC70_24360	COG0183	Belongs to the thiolase family
EHC70_24380	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC70_24385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC70_24415	COG1522	sequence-specific DNA binding
EHC70_24435	COG1566	PFAM secretion protein HlyD family protein
EHC70_24445	COG0784	Response regulator, receiver
EHC70_24445	COG2205	protein histidine kinase activity
EHC70_24450	COG1879	ABC-type sugar transport system periplasmic component
EHC70_24455	COG2827	Endonuclease containing a URI domain
EHC70_24460	COG3132	Protein of unknown function, DUF480
EHC70_24475	COG2926	Belongs to the UPF0265 family
EHC70_24480	COG0534	Mate efflux family protein
EHC70_24485	COG0673	inositol 2-dehydrogenase activity
EHC70_24490	COG5002	protein histidine kinase activity
EHC70_24490	COG0784	Response regulator, receiver
EHC70_24490	COG2205	protein histidine kinase activity
EHC70_24515	COG1522	sequence-specific DNA binding
EHC70_24525	COG0531	amino acid
EHC70_24540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC70_24545	COG2239	Acts as a magnesium transporter
EHC70_24550	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EHC70_24555	COG0402	S-adenosylhomocysteine deaminase activity
EHC70_24565	COG1418	mRNA catabolic process
EHC70_24580	COG2814	Major facilitator Superfamily
EHC70_24590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC70_24610	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC70_24630	COG4221	oxidoreductase activity
EHC70_24635	COG0745	RESPONSE REGULATOR receiver
EHC70_24640	COG2205	protein histidine kinase activity
EHC70_24650	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC70_24655	COG2194	sulfuric ester hydrolase activity
EHC70_24660	COG0673	inositol 2-dehydrogenase activity
EHC70_24670	COG2814	Major facilitator Superfamily
EHC70_24685	COG1846	Transcriptional regulator
EHC70_24695	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC70_24700	COG1741	Belongs to the pirin family
EHC70_24705	COG1278	Cold shock
EHC70_24725	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC70_24745	COG1686	Belongs to the peptidase S11 family
EHC70_24760	COG0625	glutathione transferase activity
EHC70_24770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EHC70_24775	COG0494	nUDIX hydrolase
EHC70_24780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHC70_24800	COG1028	Short-chain dehydrogenase reductase Sdr
EHC70_24820	COG3746	phosphate-selective porin O and P
EHC70_24840	COG3833	ABC-type maltose transport systems, permease component
EHC70_24845	COG1175	transmembrane transport
EHC70_24855	COG3842	ATPase activity
EHC70_24920	COG1309	transcriptional regulator
EHC70_24925	COG2130	NADP-dependent
EHC70_24935	COG0753	catalase activity
EHC70_24940	COG2084	Dehydrogenase
EHC70_24945	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC70_24950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC70_24960	COG2207	Transcriptional regulator
EHC70_24965	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC70_24965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC70_24965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC70_24980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC70_24985	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EHC70_24995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC70_25000	COG0569	domain protein
EHC70_25010	COG5002	protein histidine kinase activity
EHC70_25015	COG1132	(ABC) transporter
EHC70_25020	COG4774	siderophore transport
EHC70_25025	COG1120	ATPase activity
EHC70_25030	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC70_25045	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EHC70_25045	COG2885	chlorophyll binding
EHC70_25080	COG2197	response regulator
EHC70_25090	COG0840	transmembrane signaling receptor activity
EHC70_25100	COG0714	Associated with various cellular activities
EHC70_25120	COG2304	oxidoreductase activity
EHC70_25135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC70_25140	COG0581	inorganic phosphate transmembrane transporter activity
EHC70_25145	COG0573	inorganic phosphate transmembrane transporter activity
EHC70_25150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC70_25175	COG4771	TonB-dependent receptor
EHC70_25180	COG1770	oligopeptidase
EHC70_25185	COG0513	Belongs to the DEAD box helicase family
EHC70_25195	COG1376	ErfK ybiS ycfS ynhG family protein
EHC70_25195	COG1388	LysM domain
EHC70_25200	COG0415	Belongs to the DNA photolyase family
EHC70_25205	COG0789	Transcriptional regulator
EHC70_25210	COG3272	Protein of unknown function (DUF1722)
EHC70_25220	COG0813	purine-nucleoside phosphorylase activity
EHC70_25235	COG3706	GGDEF domain
EHC70_25245	COG1566	PFAM secretion protein HlyD family protein
EHC70_25250	COG4720	Psort location CytoplasmicMembrane, score
EHC70_25255	COG1122	ATPase activity
EHC70_25270	COG0348	domain, Protein
EHC70_25275	COG0437	4 iron, 4 sulfur cluster binding
EHC70_25280	COG1247	-acetyltransferase
EHC70_25310	COG1067	ATP-dependent peptidase activity
EHC70_25320	COG4172	Belongs to the ABC transporter superfamily
EHC70_25325	COG1505	serine-type exopeptidase activity
EHC70_25330	COG0583	DNA-binding transcription factor activity
EHC70_25335	COG1620	l-lactate permease
EHC70_25340	COG1304	FMN binding
EHC70_25350	COG0668	transmembrane transport
EHC70_25365	COG2885	chlorophyll binding
EHC70_25425	COG2337	Toxic component of a toxin-antitoxin (TA) module
EHC70_25435	COG4974	Belongs to the 'phage' integrase family
EHC70_25460	COG4932	domain protein
EHC70_25460	COG5492	domain, Protein
EHC70_25480	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EHC70_25495	COG0739	heme binding
EHC70_25800	COG3504	Conjugal transfer protein
EHC70_25820	COG4962	Type ii secretion system protein e
EHC70_25830	COG3451	type IV secretory pathway VirB4
EHC70_25835	COG5268	conjugation
EHC70_25875	COG1192	Involved in chromosome partitioning
EHC70_25915	COG5492	domain, Protein
EHC70_25915	COG4932	domain protein
EHC70_25920	COG2885	chlorophyll binding
EHC70_25920	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EHC70_25945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC70_26215	COG0419	ATPase involved in DNA repair
EHC70_26240	COG1192	Involved in chromosome partitioning
EHC70_26265	COG5268	conjugation
EHC70_26270	COG3451	type IV secretory pathway VirB4
EHC70_26280	COG4962	Type ii secretion system protein e
EHC70_26295	COG3504	Conjugal transfer protein