locus-tag	class	description
EHC64_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHC64_00010	COG0592	DNA-directed DNA polymerase activity
EHC64_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHC64_00020	COG0187	DNA topoisomerase II activity
EHC64_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
EHC64_00045	COG3977	Valine--pyruvate aminotransferase
EHC64_00050	COG0366	Alpha amylase catalytic
EHC64_00055	COG0751	glycine-tRNA ligase activity
EHC64_00060	COG0752	glycyl-tRNA synthetase alpha subunit
EHC64_00065	COG2119	membrane
EHC64_00075	COG0425	Belongs to the sulfur carrier protein TusA family
EHC64_00090	COG0604	alcohol dehydrogenase
EHC64_00095	COG0183	Belongs to the thiolase family
EHC64_00100	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC64_00100	COG1024	Enoyl-CoA hydratase
EHC64_00105	COG1739	Uncharacterized protein family UPF0029
EHC64_00110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC64_00175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHC64_00180	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EHC64_00185	COG0352	thiamine-phosphate diphosphorylase activity
EHC64_00190	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC64_00195	COG2104	thiamine diphosphate biosynthetic process
EHC64_00200	COG2022	thiamine diphosphate biosynthetic process
EHC64_00210	COG0006	proline dipeptidase activity
EHC64_00210	COG0006	proline dipeptidase activity
EHC64_00240	COG3220	belongs to the UPF0276 family
EHC64_00250	COG0210	DNA helicase
EHC64_00260	COG0405	Gamma-glutamyltransferase
EHC64_00265	COG1280	lysine exporter protein (LysE YggA)
EHC64_00275	COG2962	Rard protein
EHC64_00280	COG0514	ATP-dependent DNA helicase (RecQ)
EHC64_00295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EHC64_00300	COG0248	Ppx GppA phosphatase
EHC64_00305	COG0513	Belongs to the DEAD box helicase family
EHC64_00310	COG3118	belongs to the thioredoxin family
EHC64_00315	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EHC64_00330	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EHC64_00335	COG0633	Ferredoxin
EHC64_00390	COG3071	HemY protein
EHC64_00395	COG2959	enzyme of heme biosynthesis
EHC64_00400	COG1587	Uroporphyrinogen-III synthase
EHC64_00405	COG0181	hydroxymethylbilane synthase activity
EHC64_00410	COG3072	Adenylate cyclase
EHC64_00415	COG1965	Belongs to the frataxin family
EHC64_00425	COG0019	diaminopimelate decarboxylase activity
EHC64_00430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHC64_00440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EHC64_00445	COG1011	Hydrolase
EHC64_00450	COG2199	diguanylate cyclase activity
EHC64_00450	COG3287	FIST C domain
EHC64_00450	COG2200	EAL domain
EHC64_00470	COG0561	phosphatase activity
EHC64_00480	COG2267	carboxylic ester hydrolase activity
EHC64_00485	COG1280	lysine exporter protein (LysE YggA)
EHC64_00490	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC64_00495	COG0640	Transcriptional regulator
EHC64_00500	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC64_00555	COG2095	MarC family integral membrane protein
EHC64_00565	COG0742	ribosomal rna small subunit methyltransferase
EHC64_00570	COG0552	protein localization to endoplasmic reticulum
EHC64_00575	COG2884	Cell division ATP-binding protein ftsE
EHC64_00580	COG2177	Part of the ABC transporter FtsEX involved in
EHC64_00595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC64_00600	COG0705	Rhomboid family
EHC64_00605	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC64_00610	COG3161	chorismate lyase activity
EHC64_00615	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EHC64_00620	COG2937	Belongs to the GPAT DAPAT family
EHC64_00635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHC64_00640	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EHC64_00645	COG0534	Mate efflux family protein
EHC64_00650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC64_00710	COG2003	Belongs to the UPF0758 family
EHC64_00725	COG3339	Conserved Protein
EHC64_00780	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHC64_00785	COG4206	TonB-dependent receptor
EHC64_00795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EHC64_00860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC64_00870	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EHC64_00905	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC64_00915	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC64_00920	COG0250	Participates in transcription elongation, termination and antitermination
EHC64_00925	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHC64_00930	COG0081	regulation of translation
EHC64_00935	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHC64_00940	COG0222	ribosome binding
EHC64_00945	COG0085	RNA polymerase activity
EHC64_00950	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHC64_00955	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EHC64_00960	COG2816	NAD+ diphosphatase activity
EHC64_00975	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EHC64_00980	COG1573	uracil-dna glycosylase
EHC64_00985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC64_00990	COG3068	Protein conserved in bacteria
EHC64_00995	COG1253	flavin adenine dinucleotide binding
EHC64_01010	COG0151	Belongs to the GarS family
EHC64_01020	COG0138	bifunctional purine biosynthesis protein purh
EHC64_01030	COG0789	Transcriptional regulator
EHC64_01035	COG3710	Transcriptional regulator
EHC64_01045	COG0531	amino acid
EHC64_01050	COG1982	Orn Lys Arg decarboxylase major
EHC64_01120	COG3706	GGDEF domain
EHC64_01125	COG0488	(ABC) transporter
EHC64_01135	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EHC64_01140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC64_01145	COG2264	protein methyltransferase activity
EHC64_01155	COG0439	Biotin carboxylase
EHC64_01160	COG0511	ligase activity, forming carbon-carbon bonds
EHC64_01165	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EHC64_01170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC64_01185	COG2814	Major facilitator Superfamily
EHC64_01190	COG0784	Response regulator, receiver
EHC64_01190	COG2198	Histidine kinase
EHC64_01190	COG2205	protein histidine kinase activity
EHC64_01215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC64_01225	COG3263	regulation of cellular component size
EHC64_01235	COG4232	protein-disulfide reductase activity
EHC64_01240	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC64_01245	COG1027	Aspartate ammonia-lyase
EHC64_01250	COG3030	protein affecting phage T7 exclusion by the F plasmid
EHC64_01255	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EHC64_01265	COG2205	protein histidine kinase activity
EHC64_01270	COG0745	RESPONSE REGULATOR receiver
EHC64_01280	COG3678	ATP-independent chaperone mediated protein folding
EHC64_01290	COG0205	6-phosphofructokinase activity
EHC64_01295	COG0534	Mate efflux family protein
EHC64_01300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC64_01305	COG0459	protein refolding
EHC64_01320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC64_01330	COG1509	lysine 2,3-aminomutase activity
EHC64_01335	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC64_01345	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC64_01350	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC64_01355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC64_01360	COG1053	succinate dehydrogenase
EHC64_01370	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EHC64_01390	COG4942	peptidase
EHC64_01395	COG1045	serine acetyltransferase
EHC64_01400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EHC64_01405	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EHC64_01410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC64_01420	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EHC64_01435	COG0471	metal ion transport
EHC64_01440	COG0688	phosphatidylethanolamine metabolic process
EHC64_01445	COG1162	GTPase activity
EHC64_01450	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EHC64_01520	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHC64_01525	COG0802	atpase or kinase
EHC64_01530	COG0860	N-Acetylmuramoyl-L-alanine amidase
EHC64_01535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EHC64_01540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHC64_01550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHC64_01555	COG0330	HflC and HflK could
EHC64_01560	COG0330	HflC and HflK could
EHC64_01565	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EHC64_01570	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHC64_01580	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EHC64_01585	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC64_01585	COG1017	nitric oxide dioxygenase activity
EHC64_01590	COG1959	2 iron, 2 sulfur cluster binding
EHC64_01595	COG0557	exoribonuclease II activity
EHC64_01600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC64_01605	COG0546	phosphoglycolate phosphatase activity
EHC64_01610	COG0180	Tryptophanyl-tRNA synthetase
EHC64_01640	COG0512	Glutamine amidotransferase of anthranilate synthase
EHC64_01645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EHC64_01655	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_01665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC64_01670	COG3954	Phosphoribulokinase
EHC64_01675	COG3089	Belongs to the UPF0270 family
EHC64_01680	COG0429	hydrolase of the alpha beta-hydrolase fold
EHC64_01690	COG0488	(ABC) transporter
EHC64_01700	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC64_01715	COG1047	Peptidyl-prolyl cis-trans
EHC64_01725	COG1446	asparaginase
EHC64_01730	COG2900	Belongs to the SlyX family
EHC64_01740	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC64_01745	COG2964	Protein conserved in bacteria
EHC64_01750	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EHC64_01755	COG2923	Belongs to the DsrF TusC family
EHC64_01760	COG2168	tRNA wobble position uridine thiolation
EHC64_01770	COG0049	tRNA binding
EHC64_01775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC64_01780	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC64_01785	COG2906	2 iron, 2 sulfur cluster binding
EHC64_01795	COG0281	malic enzyme
EHC64_01805	COG0626	cystathionine gamma-synthase activity
EHC64_01810	COG0460	homoserine dehydrogenase
EHC64_01810	COG0527	aspartate kinase activity
EHC64_01815	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EHC64_01825	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EHC64_01830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC64_01835	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHC64_01840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC64_01845	COG0137	argininosuccinate synthase activity
EHC64_01850	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC64_01850	COG0165	Argininosuccinate lyase
EHC64_01865	COG0678	peroxiredoxin activity
EHC64_01865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC64_01875	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EHC64_01905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHC64_01910	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHC64_01920	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EHC64_01925	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EHC64_01930	COG0360	Binds together with S18 to 16S ribosomal RNA
EHC64_01935	COG2965	DNA replication, synthesis of RNA primer
EHC64_01945	COG0359	binds to the 23S rRNA
EHC64_01955	COG0305	Participates in initiation and elongation during chromosome replication
EHC64_01960	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC64_01970	COG0432	Pfam Uncharacterised protein family UPF0047
EHC64_01975	COG0166	Belongs to the GPI family
EHC64_01985	COG0735	belongs to the Fur family
EHC64_01995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC64_02020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHC64_02025	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC64_02030	COG0175	sulfate reduction
EHC64_02115	COG1410	methionine synthase
EHC64_02115	COG0646	methionine synthase
EHC64_02120	COG0527	aspartate kinase activity
EHC64_02130	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EHC64_02140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EHC64_02155	COG0629	single-stranded DNA binding
EHC64_02225	COG0210	DNA helicase
EHC64_02230	COG2200	EAL domain
EHC64_02230	COG2199	diguanylate cyclase activity
EHC64_02255	COG3267	Type II secretory pathway component ExeA
EHC64_02255	COG3409	Peptidoglycan-binding domain 1 protein
EHC64_02265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC64_02270	COG1459	type II secretion system
EHC64_02315	COG1077	Cell shape determining protein MreB Mrl
EHC64_02320	COG1792	Involved in formation and maintenance of cell shape
EHC64_02325	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EHC64_02330	COG0424	maF-like protein
EHC64_02335	COG1530	ribonuclease E activity
EHC64_02340	COG3164	Protein of unknown function
EHC64_02345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC64_02350	COG0312	modulator of DNA gyrase
EHC64_02355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EHC64_02360	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EHC64_02375	COG0564	pseudouridine synthase activity
EHC64_02380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC64_02385	COG3028	Belongs to the UPF0307 family
EHC64_02390	COG0312	modulator of DNA gyrase
EHC64_02395	COG2239	Acts as a magnesium transporter
EHC64_02400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_02405	COG1660	Displays ATPase and GTPase activities
EHC64_02410	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_02415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC64_02425	COG1137	ATPase activity
EHC64_02430	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EHC64_02440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EHC64_02440	COG0517	IMP dehydrogenase activity
EHC64_02450	COG1127	ABC transporter
EHC64_02455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EHC64_02460	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC64_02465	COG2854	intermembrane phospholipid transfer
EHC64_02475	COG5007	Belongs to the BolA IbaG family
EHC64_02480	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHC64_02485	COG0204	Acyl-transferase
EHC64_02490	COG0251	oxidation-reduction process
EHC64_02495	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EHC64_02500	COG0540	Belongs to the ATCase OTCase family
EHC64_02510	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHC64_02515	COG2235	arginine
EHC64_02545	COG0525	valine-tRNA ligase activity
EHC64_02550	COG2927	DNA polymerase III (CHI subunit)
EHC64_02555	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC64_02560	COG0795	lipopolysaccharide-transporting ATPase activity
EHC64_02565	COG0795	lipopolysaccharide-transporting ATPase activity
EHC64_02575	COG4325	translation initiation factor activity
EHC64_02580	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_02590	COG0726	polysaccharide deacetylase
EHC64_02595	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC64_02600	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC64_02605	COG1447	Phosphotransferase system cellobiose-specific component IIA
EHC64_02610	COG1486	melibiose metabolic process
EHC64_02615	COG3394	polysaccharide catabolic process
EHC64_02625	COG3437	response regulator, receiver
EHC64_02675	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_02705	COG0840	transmembrane signaling receptor activity
EHC64_02745	COG0741	lytic transglycosylase activity
EHC64_02750	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EHC64_02760	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EHC64_02770	COG2066	Belongs to the glutaminase family
EHC64_02775	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC64_02780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHC64_02790	COG1872	DUF167
EHC64_02795	COG0762	integral membrane protein
EHC64_02800	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHC64_02805	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EHC64_02820	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHC64_02825	COG1678	Uncharacterized ACR, COG1678
EHC64_02830	COG0189	ligase activity
EHC64_02835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EHC64_02840	COG2356	endonuclease I
EHC64_02845	COG3091	SprT-like family
EHC64_02855	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHC64_02865	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC64_02870	COG0583	DNA-binding transcription factor activity
EHC64_02875	COG4771	TonB-dependent receptor
EHC64_02880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC64_02885	COG0126	phosphoglycerate kinase activity
EHC64_02890	COG0191	fructose-bisphosphate aldolase activity
EHC64_02895	COG0668	transmembrane transport
EHC64_02900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHC64_02910	COG0583	DNA-binding transcription factor activity
EHC64_02920	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC64_02925	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EHC64_02930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHC64_02940	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EHC64_02950	COG3079	Belongs to the UPF0149 family
EHC64_02955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC64_02960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC64_02975	COG0354	folic acid binding
EHC64_02980	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EHC64_02990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EHC64_03000	COG1595	DNA-templated transcription, initiation
EHC64_03005	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EHC64_03015	COG3086	response to oxidative stress
EHC64_03020	COG0481	GTPase activity
EHC64_03025	COG0681	Belongs to the peptidase S26 family
EHC64_03030	COG0571	ribonuclease III activity
EHC64_03035	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHC64_03040	COG1381	Involved in DNA repair and RecF pathway recombination
EHC64_03045	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EHC64_03050	COG0736	holo-[acyl-carrier-protein] synthase activity
EHC64_03065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHC64_03075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC64_03080	COG3956	TIGRFAM MazG family protein
EHC64_03085	COG0504	CTP synthase activity
EHC64_03090	COG0148	phosphopyruvate hydratase activity
EHC64_03095	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EHC64_03100	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHC64_03105	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EHC64_03110	COG0585	pseudouridine synthase activity
EHC64_03115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EHC64_03120	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EHC64_03135	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHC64_03140	COG0582	viral genome integration into host DNA
EHC64_03145	COG3335	DDE superfamily endonuclease
EHC64_03180	COG2003	Belongs to the UPF0758 family
EHC64_03220	COG3501	Rhs element vgr protein
EHC64_03265	COG1546	Belongs to the CinA family
EHC64_03270	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHC64_03275	COG2137	regulation of response to DNA damage stimulus
EHC64_03280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC64_03285	COG0527	aspartate kinase activity
EHC64_03345	COG3630	sodium ion export across plasma membrane
EHC64_03350	COG0511	ligase activity, forming carbon-carbon bonds
EHC64_03350	COG5016	pyruvate
EHC64_03355	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EHC64_03360	COG1063	alcohol dehydrogenase
EHC64_03365	COG1238	metal cluster binding
EHC64_03370	COG0612	Peptidase, M16
EHC64_03375	COG2918	glutathione biosynthetic process
EHC64_03385	COG1854	S-ribosylhomocysteine lyase activity
EHC64_03390	COG4536	flavin adenine dinucleotide binding
EHC64_03395	COG4137	Cytochrome C assembly protein
EHC64_03400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHC64_03405	COG0228	four-way junction DNA binding
EHC64_03410	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHC64_03415	COG0336	Belongs to the RNA methyltransferase TrmD family
EHC64_03420	COG0335	large ribosomal subunit rRNA binding
EHC64_03425	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EHC64_03430	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EHC64_03435	COG0237	dephospho-CoA kinase activity
EHC64_03445	COG1459	type II secretion system
EHC64_03450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC64_03465	COG0157	Belongs to the NadC ModD family
EHC64_03475	COG2186	Transcriptional regulator
EHC64_03480	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EHC64_03485	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHC64_03490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC64_03505	COG0288	reversible hydration of carbon dioxide
EHC64_03510	COG0659	secondary active sulfate transmembrane transporter activity
EHC64_03520	COG1131	(ABC) transporter
EHC64_03525	COG0842	Transport permease protein
EHC64_03535	COG1560	Kdo2-lipid A biosynthetic process
EHC64_03545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHC64_03550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EHC64_03555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHC64_03570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC64_03580	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC64_03585	COG1489	DNA binding
EHC64_03590	COG1643	Atp-dependent helicase
EHC64_03595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC64_03600	COG1752	Esterase of the alpha-beta hydrolase superfamily
EHC64_03605	COG1049	propionate catabolic process, 2-methylcitrate cycle
EHC64_03610	COG3112	Uncharacterised protein family (UPF0231)
EHC64_03620	COG0004	ammonium transporteR
EHC64_03625	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC64_03635	COG3842	ATPase activity
EHC64_03640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC64_03655	COG2971	BadF BadG BcrA BcrD
EHC64_03665	COG4608	Belongs to the ABC transporter superfamily
EHC64_03670	COG0444	Belongs to the ABC transporter superfamily
EHC64_03675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC64_03685	COG0747	negative chemotaxis
EHC64_03690	COG2198	Histidine kinase
EHC64_03690	COG0784	Response regulator, receiver
EHC64_03690	COG2205	protein histidine kinase activity
EHC64_03690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_03700	COG2813	Specifically methylates the guanine in position
EHC64_03705	COG0628	permease
EHC64_03710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHC64_03715	COG0316	Belongs to the HesB IscA family
EHC64_03725	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_03730	COG0739	heme binding
EHC64_03735	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC64_03745	COG2027	D-alanyl-D-alanine carboxypeptidase
EHC64_03750	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC64_03755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC64_03760	COG1534	Rna-binding protein
EHC64_03765	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EHC64_03770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHC64_03775	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHC64_03780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC64_03790	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC64_03805	COG0779	Required for maturation of 30S ribosomal subunits
EHC64_03810	COG0195	Participates in both transcription termination and antitermination
EHC64_03815	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHC64_03820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHC64_03825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHC64_03830	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHC64_03835	COG1185	polyribonucleotide nucleotidyltransferase activity
EHC64_03850	COG0534	Mate efflux family protein
EHC64_03875	COG3153	acetyltransferase
EHC64_03895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EHC64_03905	COG0084	hydrolase, TatD family'
EHC64_03910	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC64_03915	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHC64_03920	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EHC64_03925	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHC64_03930	COG0813	purine-nucleoside phosphorylase activity
EHC64_03940	COG0560	Phosphoserine phosphatase
EHC64_03950	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHC64_03955	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC64_03960	COG0583	DNA-binding transcription factor activity
EHC64_03970	COG1022	Amp-dependent synthetase and ligase
EHC64_03975	COG2169	Transcriptional regulator
EHC64_04000	COG4964	Belongs to the GSP D family
EHC64_04065	COG0583	DNA-binding transcription factor activity
EHC64_04070	COG0531	amino acid
EHC64_04075	COG2731	YhcH YjgK YiaL family protein
EHC64_04080	COG3250	beta-galactosidase activity
EHC64_04085	COG1609	Transcriptional regulator
EHC64_04095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHC64_04105	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHC64_04110	COG2017	converts alpha-aldose to the beta-anomer
EHC64_04125	COG2211	Major facilitator Superfamily
EHC64_04130	COG1609	Transcriptional regulator
EHC64_04135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC64_04150	COG0598	Magnesium transport protein CorA
EHC64_04155	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EHC64_04160	COG1349	DNA-binding transcription factor activity
EHC64_04165	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHC64_04170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC64_04185	COG2271	Major facilitator Superfamily
EHC64_04190	COG0584	glycerophosphoryl diester phosphodiesterase
EHC64_04195	COG2171	N-acyltransferase activity
EHC64_04200	COG3141	response to X-ray
EHC64_04220	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EHC64_04230	COG1074	ATP-dependent DNA helicase activity
EHC64_04235	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EHC64_04245	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC64_04245	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC64_04260	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EHC64_04265	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EHC64_04270	COG2166	iron-sulfur cluster assembly
EHC64_04275	COG3706	GGDEF domain
EHC64_04280	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHC64_04285	COG0693	protein deglycase activity
EHC64_04290	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHC64_04295	COG3248	Nucleoside-binding outer membrane protein
EHC64_04320	COG1595	DNA-templated transcription, initiation
EHC64_04340	COG3056	Lipoprotein
EHC64_04345	COG2813	Specifically methylates the guanine in position
EHC64_04350	COG0271	Belongs to the BolA IbaG family
EHC64_04355	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC64_04360	COG1805	sodium ion transport
EHC64_04365	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC64_04370	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC64_04375	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC64_04380	COG2871	sodium ion transport
EHC64_04385	COG1477	protein flavinylation
EHC64_04400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHC64_04405	COG0514	ATP-dependent DNA helicase (RecQ)
EHC64_04410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC64_04425	COG0733	neurotransmitter:sodium symporter activity
EHC64_04445	COG0442	prolyl-tRNA aminoacylation
EHC64_04450	COG1720	tRNA m6t6A37 methyltransferase activity
EHC64_04455	COG0254	rRNA binding
EHC64_04470	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC64_04475	COG1671	Belongs to the UPF0178 family
EHC64_04500	COG3098	single-species biofilm formation
EHC64_04505	COG0564	pseudouridine synthase activity
EHC64_04515	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EHC64_04520	COG0024	Methionine aminopeptidase
EHC64_04525	COG0052	Belongs to the universal ribosomal protein uS2 family
EHC64_04530	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHC64_04535	COG0528	UMP kinase activity
EHC64_04540	COG0233	cytoplasmic translational termination
EHC64_04545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHC64_04550	COG0575	Belongs to the CDS family
EHC64_04555	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EHC64_04560	COG0750	zinc metalloprotease
EHC64_04570	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EHC64_04575	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC64_04580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC64_04585	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC64_04590	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC64_04595	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHC64_04600	COG0587	DNA-directed DNA polymerase activity
EHC64_04605	COG0825	malonyl-CoA metabolic process
EHC64_04610	COG0037	tRNA processing
EHC64_04620	COG0347	Belongs to the P(II) protein family
EHC64_04625	COG3021	interspecies interaction between organisms
EHC64_04635	COG1388	LysM domain
EHC64_04635	COG0741	lytic transglycosylase activity
EHC64_04640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC64_04645	COG2226	methyltransferase
EHC64_04650	COG0328	RNA-DNA hybrid ribonuclease activity
EHC64_04655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC64_04670	COG1960	acyl-CoA dehydrogenase activity
EHC64_04675	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC64_04680	COG0121	glutamine amidotransferase
EHC64_04685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHC64_04690	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EHC64_04695	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHC64_04700	COG2233	PERMEase
EHC64_04720	COG1393	Belongs to the ArsC family
EHC64_04725	COG4783	chaperone-mediated protein folding
EHC64_04740	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EHC64_04745	COG2716	regulation of RNA biosynthetic process
EHC64_04750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC64_04770	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC64_04775	COG1393	Belongs to the ArsC family
EHC64_04805	COG2837	iron assimilation
EHC64_04810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_04820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_04825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_04830	COG1334	flagellar protein FlaG
EHC64_04835	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHC64_04845	COG1516	flagellar protein fliS
EHC64_04855	COG4191	Histidine kinase
EHC64_04860	COG2204	response regulator
EHC64_04865	COG1677	Flagellar hook-basal body complex protein FliE
EHC64_04875	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC64_04925	COG1987	bacterial-type flagellum assembly
EHC64_04950	COG0455	bacterial-type flagellum organization
EHC64_04965	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EHC64_04970	COG0643	Histidine kinase
EHC64_04970	COG2198	Histidine kinase
EHC64_04975	COG2201	protein-glutamate methylesterase activity
EHC64_04980	COG1192	Involved in chromosome partitioning
EHC64_04990	COG0835	chemotaxis
EHC64_05000	COG4133	protoheme IX ABC transporter activity
EHC64_05005	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC64_05010	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC64_05015	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC64_05020	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EHC64_05025	COG1138	Cytochrome C-type biogenesis protein
EHC64_05030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EHC64_05045	COG2853	Lipoprotein
EHC64_05055	COG2067	long-chain fatty acid transport protein
EHC64_05075	COG0183	Belongs to the thiolase family
EHC64_05080	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC64_05080	COG1024	Enoyl-CoA hydratase
EHC64_05095	COG2062	phosphohistidine phosphatase, SixA
EHC64_05100	COG2840	Smr protein MutS2
EHC64_05105	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC64_05110	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHC64_05115	COG2860	membrane
EHC64_05125	COG3101	peptidyl-lysine hydroxylation
EHC64_05140	COG0431	NADPH-dependent FMN reductase
EHC64_05145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC64_05145	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EHC64_05150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC64_05160	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC64_05165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC64_05175	COG0101	tRNA pseudouridine synthase activity
EHC64_05180	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC64_05185	COG0285	dihydrofolate synthase activity
EHC64_05190	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EHC64_05195	COG1286	toxin biosynthetic process
EHC64_05200	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHC64_05205	COG0583	DNA-binding transcription factor activity
EHC64_05210	COG0745	RESPONSE REGULATOR receiver
EHC64_05220	COG2832	Protein of unknown function (DUF454)
EHC64_05225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHC64_05235	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHC64_05240	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHC64_05245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC64_05250	COG0814	amino acid
EHC64_05255	COG0251	oxidation-reduction process
EHC64_05260	COG3681	Belongs to the UPF0597 family
EHC64_05275	COG2261	transglycosylase associated protein
EHC64_05280	COG2983	Belongs to the UPF0260 family
EHC64_05285	COG0668	transmembrane transport
EHC64_05290	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EHC64_05295	COG0346	lactoylglutathione lyase activity
EHC64_05305	COG1785	Belongs to the alkaline phosphatase family
EHC64_05325	COG2226	methyltransferase
EHC64_05340	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC64_05345	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC64_05355	COG3139	Protein of unknown function (DUF1315)
EHC64_05360	COG0252	asparaginase activity
EHC64_05365	COG0616	signal peptide processing
EHC64_05370	COG0446	pyridine nucleotide-disulphide oxidoreductase
EHC64_05370	COG1902	pentaerythritol trinitrate reductase activity
EHC64_05375	COG0778	Nitroreductase
EHC64_05380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC64_05400	COG0123	including yeast histone deacetylase and acetoin utilization protein
EHC64_05410	COG3083	sulfuric ester hydrolase activity
EHC64_05415	COG3082	Protein of unknown function (DUF1414)
EHC64_05420	COG3081	Nucleoid-associated protein
EHC64_05435	COG1757	Na H antiporter
EHC64_05440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC64_05445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC64_05450	COG2095	MarC family integral membrane protein
EHC64_05455	COG1454	alcohol dehydrogenase
EHC64_05455	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_05475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EHC64_05485	COG2056	Na+-H+ antiporter family
EHC64_05490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC64_05505	COG2885	chlorophyll binding
EHC64_05515	COG0346	lactoylglutathione lyase activity
EHC64_05520	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHC64_05525	COG4660	Part of a membrane complex involved in electron transport
EHC64_05530	COG4659	FMN binding
EHC64_05535	COG4658	electron transport chain
EHC64_05540	COG4656	Part of a membrane complex involved in electron transport
EHC64_05545	COG2878	Part of a membrane complex involved in electron transport
EHC64_05550	COG4657	Part of a membrane complex involved in electron transport
EHC64_05565	COG0556	nucleotide-excision repair
EHC64_05570	COG2204	response regulator
EHC64_05575	COG2198	Histidine kinase
EHC64_05580	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EHC64_05585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHC64_05590	COG0521	Mo-molybdopterin cofactor biosynthetic process
EHC64_05595	COG0315	cyclic pyranopterin monophosphate synthase activity
EHC64_05600	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EHC64_05605	COG0314	molybdopterin synthase activity
EHC64_05615	COG0601	transmembrane transport
EHC64_05620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC64_05625	COG0444	Belongs to the ABC transporter superfamily
EHC64_05635	COG0435	Glutathione S-transferase
EHC64_05645	COG3174	membrane
EHC64_05650	COG0857	belongs to the CobB CobQ family
EHC64_05650	COG0280	phosphate acetyltransferase
EHC64_05655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC64_05660	COG3092	negative regulation of chromosome organization
EHC64_05670	COG4120	Belongs to the binding-protein-dependent transport system permease family
EHC64_05675	COG1122	ATPase activity
EHC64_05680	COG0366	Alpha amylase catalytic
EHC64_05685	COG0745	RESPONSE REGULATOR receiver
EHC64_05685	COG3706	GGDEF domain
EHC64_05690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC64_05695	COG0653	protein targeting
EHC64_05700	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EHC64_05705	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC64_05710	COG2186	Transcriptional regulator
EHC64_05720	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC64_05720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC64_05725	COG0489	protein tyrosine kinase activity
EHC64_05730	COG0572	uridine kinase
EHC64_05740	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EHC64_05745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHC64_05750	COG0659	secondary active sulfate transmembrane transporter activity
EHC64_05760	COG1530	ribonuclease E activity
EHC64_05775	COG0564	pseudouridine synthase activity
EHC64_05780	COG0424	maF-like protein
EHC64_05785	COG1399	metal-binding, possibly nucleic acid-binding protein
EHC64_05795	COG0416	fatty acid biosynthetic process
EHC64_05800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC64_05830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHC64_05835	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHC64_05845	COG0084	hydrolase, TatD family'
EHC64_05850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC64_05850	COG1263	PTS System
EHC64_05870	COG0733	neurotransmitter:sodium symporter activity
EHC64_05885	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC64_05890	COG0469	pyruvate kinase activity
EHC64_05895	COG1940	carbohydrate kinase activity
EHC64_05900	COG0835	chemotaxis
EHC64_05900	COG0784	Response regulator, receiver
EHC64_05905	COG0587	DNA-directed DNA polymerase activity
EHC64_05920	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_05925	COG0616	signal peptide processing
EHC64_05930	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EHC64_05935	COG0539	negative regulation of cytoplasmic translation
EHC64_05945	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EHC64_05950	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EHC64_05955	COG0284	orotidine-5'-phosphate decarboxylase activity
EHC64_05960	COG4166	transmembrane transport
EHC64_05985	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHC64_05995	COG3008	intermembrane lipid transfer
EHC64_05995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC64_06000	COG2995	paraquat-inducible protein a
EHC64_06005	COG3258	Cytochrome c
EHC64_06010	COG2863	cytochrome
EHC64_06050	COG4232	protein-disulfide reductase activity
EHC64_06055	COG3118	belongs to the thioredoxin family
EHC64_06085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_06095	COG0577	efflux transmembrane transporter activity
EHC64_06095	COG1136	(ABC) transporter
EHC64_06100	COG0577	efflux transmembrane transporter activity
EHC64_06100	COG1136	(ABC) transporter
EHC64_06105	COG1136	(ABC) transporter
EHC64_06105	COG0577	efflux transmembrane transporter activity
EHC64_06110	COG1335	isochorismatase
EHC64_06125	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC64_06155	COG3850	Histidine kinase
EHC64_06155	COG5002	protein histidine kinase activity
EHC64_06160	COG0745	RESPONSE REGULATOR receiver
EHC64_06215	COG0840	transmembrane signaling receptor activity
EHC64_06220	COG1032	radical SAM domain protein
EHC64_06225	COG3706	GGDEF domain
EHC64_06225	COG2203	Gaf domain
EHC64_06225	COG5001	Diguanylate cyclase
EHC64_06225	COG4251	negative regulation of phosphorylation
EHC64_06240	COG0583	DNA-binding transcription factor activity
EHC64_06250	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC64_06260	COG2350	Protein conserved in bacteria
EHC64_06265	COG1607	acyl-coa hydrolase
EHC64_06270	COG2917	probably involved in intracellular septation
EHC64_06290	COG1301	dicarboxylic acid transport
EHC64_06300	COG0318	PFAM AMP-dependent synthetase and ligase
EHC64_06305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC64_06315	COG0159	tryptophan synthase activity
EHC64_06320	COG0133	tryptophan synthase activity
EHC64_06325	COG0134	indole-3-glycerol-phosphate synthase activity
EHC64_06325	COG0135	phosphoribosylanthranilate isomerase activity
EHC64_06330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHC64_06335	COG0512	Glutamine amidotransferase of anthranilate synthase
EHC64_06340	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC64_06350	COG0613	PHP domain protein
EHC64_06355	COG0009	L-threonylcarbamoyladenylate synthase
EHC64_06365	COG1187	pseudouridine synthase activity
EHC64_06375	COG3099	Belongs to the UPF0263 family
EHC64_06380	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC64_06390	COG0417	DNA replication proofreading
EHC64_06395	COG2197	response regulator
EHC64_06400	COG0322	excinuclease ABC activity
EHC64_06440	COG0019	diaminopimelate decarboxylase activity
EHC64_06465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC64_06470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC64_06475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC64_06495	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EHC64_06505	COG0437	4 iron, 4 sulfur cluster binding
EHC64_06510	COG3301	Polysulphide reductase, NrfD
EHC64_06515	COG1138	Cytochrome C-type biogenesis protein
EHC64_06525	COG3088	subunit of a heme lyase
EHC64_06525	COG4235	cytochrome complex assembly
EHC64_06535	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC64_06560	COG2989	Protein conserved in bacteria
EHC64_06565	COG3108	Peptidase M15
EHC64_06570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC64_06585	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EHC64_06610	COG1846	Transcriptional regulator
EHC64_06615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC64_06620	COG0840	transmembrane signaling receptor activity
EHC64_06640	COG1448	Aminotransferase
EHC64_06665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC64_06675	COG0017	Asparaginyl-tRNA synthetase
EHC64_06680	COG0840	transmembrane signaling receptor activity
EHC64_06685	COG0720	synthase
EHC64_06695	COG2200	EAL domain
EHC64_06700	COG1760	l-serine dehydratase
EHC64_06705	COG0814	amino acid
EHC64_06710	COG0494	nUDIX hydrolase
EHC64_06720	COG0784	Response regulator, receiver
EHC64_06720	COG2205	protein histidine kinase activity
EHC64_06725	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC64_06745	COG3106	COG3106 Predicted ATPase
EHC64_06750	COG3768	UPF0283 membrane protein
EHC64_06760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC64_06890	COG0454	-acetyltransferase
EHC64_07120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHC64_07380	COG0625	glutathione transferase activity
EHC64_07585	COG2314	TM2 domain
EHC64_07660	COG0494	nUDIX hydrolase
EHC64_07735	COG1757	Na H antiporter
EHC64_07740	COG0174	glutamine synthetase
EHC64_07750	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EHC64_07755	COG1917	Cupin 2, conserved barrel domain protein
EHC64_07755	COG1396	sequence-specific DNA binding
EHC64_07760	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_07765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC64_07775	COG2957	Belongs to the agmatine deiminase family
EHC64_07780	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_07785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC64_07790	COG1227	inorganic diphosphatase activity
EHC64_07800	COG2200	EAL domain
EHC64_07800	COG2771	luxR family
EHC64_07815	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC64_07830	COG1846	Transcriptional regulator
EHC64_07835	COG2315	Protein conserved in bacteria
EHC64_07855	COG0110	maltose O-acetyltransferase activity
EHC64_07885	COG3063	Type IV pilus biogenesis stability protein PilW
EHC64_07890	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EHC64_07905	COG0531	amino acid
EHC64_07915	COG1560	Kdo2-lipid A biosynthetic process
EHC64_07920	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EHC64_07925	COG1280	lysine exporter protein (LysE YggA)
EHC64_07935	COG1115	amino acid carrier protein
EHC64_07960	COG1368	sulfuric ester hydrolase activity
EHC64_07965	COG0642	Histidine kinase
EHC64_07970	COG0745	RESPONSE REGULATOR receiver
EHC64_07980	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_08000	COG2113	Glycine betaine
EHC64_08005	COG4176	ABC-type proline glycine betaine transport system permease component
EHC64_08025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC64_08030	COG0456	acetyltransferase
EHC64_08035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC64_08040	COG0662	Cupin 2, conserved barrel domain protein
EHC64_08045	COG0527	aspartate kinase activity
EHC64_08050	COG1858	cytochrome C peroxidase
EHC64_08065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_08080	COG3290	protein histidine kinase activity
EHC64_08085	COG4565	transcriptional regulatory protein
EHC64_08095	COG0363	glucosamine-6-phosphate deaminase activity
EHC64_08100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHC64_08125	COG3284	Transcriptional regulator
EHC64_08130	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_08200	COG4669	(LipO)protein
EHC64_08220	COG3177	Filamentation induced by cAMP protein fic
EHC64_08260	COG1073	alpha beta
EHC64_08265	COG1073	alpha beta
EHC64_08275	COG4792	protein secretion
EHC64_08280	COG4791	protein targeting
EHC64_08285	COG4794	Type iii secretion
EHC64_08290	COG4790	Type iii secretion
EHC64_08295	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC64_08360	COG0457	Tetratricopeptide repeat
EHC64_08380	COG0730	response to heat
EHC64_08410	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHC64_08415	COG0372	Belongs to the citrate synthase family
EHC64_08425	COG2828	Protein conserved in bacteria
EHC64_08460	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EHC64_08505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC64_08510	COG0840	transmembrane signaling receptor activity
EHC64_08515	COG1254	Belongs to the acylphosphatase family
EHC64_08520	COG2920	part of a sulfur-relay system
EHC64_08530	COG0670	Belongs to the BI1 family
EHC64_08535	COG1126	abc transporter atp-binding protein
EHC64_08540	COG0765	amino acid transport
EHC64_08545	COG4597	amino acid ABC transporter
EHC64_08550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_08575	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC64_08595	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC64_08595	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EHC64_08605	COG3008	intermembrane lipid transfer
EHC64_08610	COG2995	paraquat-inducible protein a
EHC64_08615	COG1132	(ABC) transporter
EHC64_08620	COG1956	GAF domain-containing protein
EHC64_08625	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EHC64_08640	COG0308	aminopeptidase N
EHC64_08650	COG2902	Dehydrogenase
EHC64_08655	COG0167	dihydroorotate dehydrogenase activity
EHC64_08670	COG0116	Belongs to the methyltransferase superfamily
EHC64_08670	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC64_08695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC64_08700	COG1067	ATP-dependent peptidase activity
EHC64_08705	COG3120	sequence-specific DNA binding
EHC64_08755	COG4128	Pfam Zonular occludens toxin
EHC64_08820	COG3278	Belongs to the heme-copper respiratory oxidase family
EHC64_08835	COG2010	Cytochrome c
EHC64_08845	COG2217	Heavy metal translocating P-type atpase
EHC64_08860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC64_08865	COG0589	response to stress
EHC64_08875	COG0037	tRNA processing
EHC64_08895	COG3842	ATPase activity
EHC64_08900	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC64_08905	COG1177	transmembrane transport
EHC64_08910	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC64_08920	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EHC64_08930	COG0004	ammonium transporteR
EHC64_08955	COG0437	4 iron, 4 sulfur cluster binding
EHC64_08960	COG0243	molybdopterin cofactor binding
EHC64_08960	COG3383	formate dehydrogenase (NAD+) activity
EHC64_08970	COG3381	protein complex oligomerization
EHC64_08995	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC64_09000	COG0488	(ABC) transporter
EHC64_09010	COG4191	Histidine kinase
EHC64_09015	COG2204	response regulator
EHC64_09035	COG3842	ATPase activity
EHC64_09040	COG0746	molybdenum cofactor guanylyltransferase activity
EHC64_09045	COG0303	'Molybdopterin
EHC64_09055	COG1940	carbohydrate kinase activity
EHC64_09095	COG0840	transmembrane signaling receptor activity
EHC64_09095	COG3290	protein histidine kinase activity
EHC64_09100	COG0791	NLP P60 protein
EHC64_09110	COG3706	GGDEF domain
EHC64_09115	COG2201	protein-glutamate methylesterase activity
EHC64_09130	COG0307	riboflavin synthase, alpha
EHC64_09135	COG0534	Mate efflux family protein
EHC64_09145	COG1793	dna ligase
EHC64_09180	COG2204	response regulator
EHC64_09225	COG0438	transferase activity, transferring glycosyl groups
EHC64_09230	COG1215	transferase activity, transferring glycosyl groups
EHC64_09235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC64_09245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC64_09260	COG1643	Atp-dependent helicase
EHC64_09265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHC64_09280	COG3302	dmso reductase anchor subunit
EHC64_09285	COG0437	4 iron, 4 sulfur cluster binding
EHC64_09290	COG0243	molybdopterin cofactor binding
EHC64_09330	COG0443	Heat shock 70 kDa protein
EHC64_09335	COG0443	Heat shock 70 kDa protein
EHC64_09365	COG1132	(ABC) transporter
EHC64_09370	COG1132	(ABC) transporter
EHC64_09395	COG0814	amino acid
EHC64_09410	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EHC64_09500	COG1522	sequence-specific DNA binding
EHC64_09535	COG0515	serine threonine protein kinase
EHC64_09560	COG3501	Rhs element vgr protein
EHC64_09575	COG2204	response regulator
EHC64_09600	COG0739	heme binding
EHC64_09610	COG0861	Integral membrane protein TerC family
EHC64_09620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC64_09625	COG1328	CTP reductase activity
EHC64_09630	COG1280	lysine exporter protein (LysE YggA)
EHC64_09640	COG3300	MHYT domain
EHC64_09640	COG5001	Diguanylate cyclase
EHC64_09650	COG4191	Histidine kinase
EHC64_09650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_09655	COG0471	metal ion transport
EHC64_09690	COG0583	DNA-binding transcription factor activity
EHC64_09695	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC64_09755	COG0625	glutathione transferase activity
EHC64_09765	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EHC64_09780	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC64_09790	COG0601	transmembrane transport
EHC64_09795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC64_09800	COG0444	Belongs to the ABC transporter superfamily
EHC64_09820	COG3291	Pkd domain containing protein
EHC64_09835	COG1177	transmembrane transport
EHC64_09840	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC64_09845	COG3842	ATPase activity
EHC64_09850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC64_09855	COG2423	ornithine cyclodeaminase activity
EHC64_09875	COG3938	Belongs to the proline racemase family
EHC64_09905	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EHC64_09910	COG1451	nucleotide metabolic process
EHC64_09915	COG3475	LICD family
EHC64_09920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EHC64_09925	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHC64_09945	COG0583	DNA-binding transcription factor activity
EHC64_09965	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EHC64_09970	COG4139	cobalamin transport
EHC64_09975	COG2988	succinylglutamate desuccinylase activity
EHC64_10000	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EHC64_10005	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EHC64_10010	COG0702	epimerase
EHC64_10020	COG2925	Exonuclease
EHC64_10025	COG1380	Effector of murein hydrolase LrgA
EHC64_10030	COG1346	cytolysis
EHC64_10035	COG0295	cytidine deaminase activity
EHC64_10040	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EHC64_10045	COG0500	methyltransferase
EHC64_10055	COG0776	regulation of translation
EHC64_10070	COG0072	phenylalanine-tRNA ligase activity
EHC64_10070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC64_10075	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHC64_10080	COG3706	GGDEF domain
EHC64_10110	COG0393	Putative heavy-metal-binding
EHC64_10120	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EHC64_10130	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHC64_10145	COG2188	Transcriptional regulator
EHC64_10150	COG1228	amidohydrolase
EHC64_10155	COG0010	Belongs to the arginase family
EHC64_10160	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EHC64_10165	COG2986	histidine ammonia-lyase
EHC64_10180	COG0247	lactate metabolic process
EHC64_10180	COG0277	FAD linked oxidase domain protein
EHC64_10215	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EHC64_10230	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EHC64_10235	COG1643	Atp-dependent helicase
EHC64_10240	COG0281	malic enzyme
EHC64_10245	COG2949	membrane
EHC64_10250	COG0471	metal ion transport
EHC64_10255	COG0745	RESPONSE REGULATOR receiver
EHC64_10255	COG3706	GGDEF domain
EHC64_10275	COG0492	ferredoxin-NADP+ reductase activity
EHC64_10280	COG4988	ABC transporter
EHC64_10285	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EHC64_10290	COG3048	D-serine ammonia-lyase activity
EHC64_10295	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHC64_10305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_10305	COG4191	Histidine kinase
EHC64_10320	COG3070	regulator of competence-specific genes
EHC64_10340	COG2431	L-lysine efflux transmembrane transporter activity
EHC64_10350	COG0076	glutamate decarboxylase activity
EHC64_10355	COG1737	Transcriptional regulator
EHC64_10370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC64_10375	COG3273	potassium ion transport
EHC64_10375	COG2985	domain, Protein
EHC64_10380	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EHC64_10395	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC64_10410	COG4181	ATPase activity
EHC64_10415	COG0534	Mate efflux family protein
EHC64_10420	COG0702	epimerase
EHC64_10425	COG3005	denitrification pathway
EHC64_10455	COG2814	Major facilitator Superfamily
EHC64_10460	COG1187	pseudouridine synthase activity
EHC64_10465	COG1061	Type III restriction enzyme res subunit
EHC64_10475	COG0745	RESPONSE REGULATOR receiver
EHC64_10480	COG2205	protein histidine kinase activity
EHC64_10485	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EHC64_10515	COG3313	Fe-S protein
EHC64_10540	COG0493	'glutamate synthase
EHC64_10550	COG0398	Pfam SNARE associated Golgi protein
EHC64_10555	COG4134	Bacterial extracellular solute-binding protein
EHC64_10560	COG4135	transport system, permease component
EHC64_10565	COG4136	ATPase activity
EHC64_10570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHC64_10585	COG3604	Transcriptional regulator
EHC64_10590	COG1151	hydroxylamine reductase activity
EHC64_10595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC64_10605	COG0564	pseudouridine synthase activity
EHC64_10615	COG0733	neurotransmitter:sodium symporter activity
EHC64_10625	COG0626	cystathionine gamma-synthase activity
EHC64_10630	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EHC64_10635	COG5380	lipid catabolic process
EHC64_10640	COG2818	Glycosylase
EHC64_10655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_10660	COG1983	PspC domain protein
EHC64_10670	COG1842	Phage shock protein A
EHC64_10675	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EHC64_10685	COG4168	peptide transport system, permease
EHC64_10690	COG4171	peptide transport system, permease
EHC64_10700	COG4172	Belongs to the ABC transporter superfamily
EHC64_10710	COG1227	inorganic diphosphatase activity
EHC64_10725	COG0243	molybdopterin cofactor binding
EHC64_10730	COG3005	denitrification pathway
EHC64_10735	COG4459	periplasmic nitrate reductase
EHC64_10740	COG0390	transport system, permease component
EHC64_10750	COG2116	formate transmembrane transporter activity
EHC64_10775	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC64_10780	COG1435	thymidine kinase activity
EHC64_10785	COG0215	cysteine-tRNA ligase activity
EHC64_10790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC64_10795	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC64_10800	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC64_10810	COG3012	SEC-C Motif Domain Protein
EHC64_10815	COG0140	phosphoribosyl-ATP diphosphatase activity
EHC64_10815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EHC64_10820	COG0107	imidazoleglycerol-phosphate synthase activity
EHC64_10825	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHC64_10830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHC64_10835	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC64_10835	COG0131	Imidazoleglycerol-phosphate dehydratase
EHC64_10840	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHC64_10845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHC64_10850	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EHC64_10865	COG1757	Na H antiporter
EHC64_10875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC64_10885	COG0482	sulfurtransferase activity
EHC64_10890	COG2915	High frequency lysogenization protein hflD homolog
EHC64_10895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EHC64_10920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EHC64_10935	COG0300	oxidoreductase activity
EHC64_10945	COG0501	Belongs to the peptidase M48B family
EHC64_10955	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EHC64_10965	COG0156	8-amino-7-oxononanoate synthase activity
EHC64_10970	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHC64_10975	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC64_10980	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC64_10995	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHC64_11000	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EHC64_11005	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EHC64_11010	COG1674	ftsk spoiiie
EHC64_11020	COG0686	Belongs to the AlaDH PNT family
EHC64_11030	COG0583	DNA-binding transcription factor activity
EHC64_11045	COG3568	Endonuclease Exonuclease Phosphatase
EHC64_11075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_11080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_11095	COG0840	transmembrane signaling receptor activity
EHC64_11205	COG5002	protein histidine kinase activity
EHC64_11205	COG0784	Response regulator, receiver
EHC64_11215	COG0754	glutathionylspermidine amidase activity
EHC64_11225	COG3766	membrane
EHC64_11235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHC64_11240	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EHC64_11245	COG2885	chlorophyll binding
EHC64_11250	COG0823	Involved in the tonB-independent uptake of proteins
EHC64_11265	COG0811	peptide transport
EHC64_11270	COG0824	Thioesterase
EHC64_11280	COG4890	Cyd operon protein YbgT
EHC64_11285	COG1294	oxidase, subunit
EHC64_11290	COG1271	oxidase subunit
EHC64_11295	COG2255	four-way junction helicase activity
EHC64_11300	COG0632	four-way junction helicase activity
EHC64_11305	COG0840	transmembrane signaling receptor activity
EHC64_11310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EHC64_11315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EHC64_11320	COG1801	Protein of unknown function DUF72
EHC64_11325	COG4106	trans-aconitate 2-methyltransferase activity
EHC64_11330	COG0500	methyltransferase
EHC64_11340	COG4067	protein conserved in archaea
EHC64_11340	COG0189	ligase activity
EHC64_11360	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC64_11365	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EHC64_11370	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EHC64_11375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC64_11380	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC64_11385	COG0745	RESPONSE REGULATOR receiver
EHC64_11390	COG3381	protein complex oligomerization
EHC64_11395	COG1609	Transcriptional regulator
EHC64_11400	COG3070	regulator of competence-specific genes
EHC64_11420	COG0297	glycogen (starch) synthase activity
EHC64_11425	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC64_11430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC64_11440	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EHC64_11450	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EHC64_11455	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EHC64_11460	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHC64_11470	COG0542	response to heat
EHC64_11475	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EHC64_11480	COG1278	Cold shock
EHC64_11490	COG1187	pseudouridine synthase activity
EHC64_11495	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC64_11505	COG1199	ATP-dependent helicase activity
EHC64_11510	COG0730	response to heat
EHC64_11515	COG3923	Primosomal replication protein n
EHC64_11525	COG0708	Exodeoxyribonuclease III
EHC64_11540	COG4215	(ABC) transporter
EHC64_11570	COG1882	Formate acetyltransferase
EHC64_11580	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC64_11590	COG3013	Belongs to the UPF0304 family
EHC64_11600	COG2766	serine protein kinase
EHC64_11605	COG2718	Belongs to the UPF0229 family
EHC64_11610	COG2719	SpoVR family
EHC64_11615	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EHC64_11625	COG1663	tetraacyldisaccharide 4'-kinase activity
EHC64_11630	COG1132	(ABC) transporter
EHC64_11635	COG0658	competence protein
EHC64_11635	COG2333	competence protein COMEC
EHC64_11645	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC64_11650	COG1136	(ABC) transporter
EHC64_11655	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC64_11665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHC64_11680	COG1252	NADH dehydrogenase
EHC64_11690	COG3150	esterase
EHC64_11715	COG0537	adenosine 5'-monophosphoramidase activity
EHC64_11745	COG0516	GMP reductase activity
EHC64_11745	COG0517	IMP dehydrogenase activity
EHC64_11755	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EHC64_11760	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC64_11765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC64_11775	COG2199	diguanylate cyclase activity
EHC64_11790	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EHC64_11795	COG1946	Acyl-CoA thioesterase
EHC64_11805	COG1522	sequence-specific DNA binding
EHC64_11835	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_11885	COG0477	Major facilitator Superfamily
EHC64_11890	COG2855	membrane
EHC64_11905	COG1441	menaquinone biosynthetic process
EHC64_11910	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EHC64_11915	COG0596	Alpha beta hydrolase
EHC64_11920	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EHC64_11925	COG1169	isochorismate synthase
EHC64_11930	COG0436	Aminotransferase
EHC64_11935	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EHC64_11940	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EHC64_11955	COG1555	photosystem II stabilization
EHC64_11960	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC64_11965	COG0776	regulation of translation
EHC64_11970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EHC64_11975	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHC64_11985	COG0544	peptidyl-prolyl cis-trans isomerase activity
EHC64_11995	COG2204	response regulator
EHC64_12005	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EHC64_12010	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC64_12015	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EHC64_12020	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EHC64_12040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC64_12045	COG0569	domain protein
EHC64_12050	COG0513	Belongs to the DEAD box helicase family
EHC64_12055	COG1253	flavin adenine dinucleotide binding
EHC64_12090	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC64_12095	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC64_12110	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC64_12115	COG1216	Glycosyl transferase, family 2
EHC64_12120	COG2986	histidine ammonia-lyase
EHC64_12145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC64_12150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC64_12155	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_12175	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHC64_12180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC64_12185	COG0583	DNA-binding transcription factor activity
EHC64_12190	COG2951	lytic endotransglycosylase activity
EHC64_12195	COG3100	YcgL domain-containing protein
EHC64_12200	COG0850	regulation of cytokinetic process
EHC64_12205	COG2894	cell division
EHC64_12210	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EHC64_12215	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EHC64_12220	COG0318	PFAM AMP-dependent synthetase and ligase
EHC64_12225	COG2267	carboxylic ester hydrolase activity
EHC64_12240	COG1214	PFAM Peptidase M22, glycoprotease
EHC64_12245	COG1199	ATP-dependent helicase activity
EHC64_12250	COG0788	formyltetrahydrofolate deformylase activity
EHC64_12255	COG3102	Protein conserved in bacteria
EHC64_12265	COG0018	arginyl-trna synthetase
EHC64_12285	COG1918	ferrous iron import across plasma membrane
EHC64_12300	COG4977	sequence-specific DNA binding
EHC64_12305	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EHC64_12310	COG1121	(ABC) transporter
EHC64_12315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC64_12325	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC64_12330	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHC64_12335	COG0567	Dehydrogenase, E1 component
EHC64_12340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC64_12345	COG1053	succinate dehydrogenase
EHC64_12350	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EHC64_12355	COG2009	succinate dehydrogenase
EHC64_12365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EHC64_12375	COG0033	Phosphoglucomutase
EHC64_12380	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EHC64_12385	COG0596	Alpha beta hydrolase
EHC64_12395	COG0716	FMN binding
EHC64_12405	COG0735	belongs to the Fur family
EHC64_12410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC64_12415	COG1263	PTS System
EHC64_12415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC64_12415	COG2190	(PTS) system
EHC64_12425	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHC64_12430	COG1940	carbohydrate kinase activity
EHC64_12430	COG1846	Transcriptional regulator
EHC64_12435	COG4651	solute:proton antiporter activity
EHC64_12435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EHC64_12440	COG0367	asparagine synthase
EHC64_12445	COG0250	Participates in transcription elongation, termination and antitermination
EHC64_12450	COG3104	oligopeptide transport
EHC64_12455	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EHC64_12460	COG0563	adenylate kinase activity
EHC64_12465	COG0326	Molecular chaperone. Has ATPase activity
EHC64_12470	COG3710	Transcriptional regulator
EHC64_12490	COG0622	Phosphoesterase
EHC64_12520	COG1090	epimerase
EHC64_12525	COG0300	oxidoreductase activity
EHC64_12535	COG3118	belongs to the thioredoxin family
EHC64_12540	COG0330	HflC and HflK could
EHC64_12565	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHC64_12570	COG3115	cell septum assembly
EHC64_12575	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EHC64_12580	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EHC64_12590	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_12595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC64_12600	COG2190	(PTS) system
EHC64_12610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_12615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_12625	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_12635	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_12645	COG1705	Flagellar rod assembly protein muramidase FlgJ
EHC64_12645	COG3951	Flagellar rod assembly protein muramidase FlgJ
EHC64_12650	COG1706	bacterial-type flagellum-dependent cell motility
EHC64_12655	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC64_12660	COG4786	Flagellar basal body rod
EHC64_12665	COG4787	bacterial-type flagellum-dependent cell motility
EHC64_12675	COG1749	Flagellar hook protein flgE
EHC64_12680	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC64_12685	COG1558	bacterial-type flagellum-dependent cell motility
EHC64_12690	COG1815	bacterial-type flagellum-dependent cell motility
EHC64_12695	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EHC64_12700	COG0784	Response regulator, receiver
EHC64_12700	COG0835	chemotaxis
EHC64_12760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC64_12765	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC64_12780	COG2217	Heavy metal translocating P-type atpase
EHC64_12780	COG2608	mercury ion transmembrane transporter activity
EHC64_12820	COG2840	Smr protein MutS2
EHC64_12825	COG1187	pseudouridine synthase activity
EHC64_12835	COG0737	Belongs to the 5'-nucleotidase family
EHC64_12840	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EHC64_12845	COG2912	Transglutaminase-like superfamily
EHC64_12850	COG3094	Invasion gene expression up-regulator, SirB
EHC64_12855	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC64_12860	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHC64_12865	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHC64_12870	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EHC64_12875	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHC64_12880	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHC64_12885	COG0193	aminoacyl-tRNA hydrolase activity
EHC64_12890	COG0012	GTP binding
EHC64_13005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC64_13015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHC64_13020	COG1702	phosphate starvation-inducible protein PhoH
EHC64_13025	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHC64_13030	COG4535	Mg2 and Co2 transporter CorC
EHC64_13035	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EHC64_13040	COG2888	peptidyl-tyrosine sulfation
EHC64_13045	COG0495	leucyl-tRNA aminoacylation
EHC64_13050	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EHC64_13055	COG1466	dna polymerase III delta subunit
EHC64_13060	COG0799	negative regulation of ribosome biogenesis
EHC64_13065	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHC64_13070	COG0768	penicillin binding
EHC64_13075	COG0772	Belongs to the SEDS family
EHC64_13080	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EHC64_13085	COG1686	Belongs to the peptidase S11 family
EHC64_13090	COG2921	Belongs to the UPF0250 family
EHC64_13095	COG0321	lipoyl(octanoyl) transferase activity
EHC64_13100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EHC64_13105	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC64_13110	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC64_13125	COG0366	Alpha amylase catalytic
EHC64_13130	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC64_13130	COG1263	PTS System
EHC64_13140	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC64_13150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHC64_13155	COG2011	ABC-type metal ion transport system permease component
EHC64_13160	COG1464	Belongs to the NlpA lipoprotein family
EHC64_13165	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
EHC64_13175	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC64_13175	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC64_13185	COG3706	GGDEF domain
EHC64_13185	COG0745	RESPONSE REGULATOR receiver
EHC64_13190	COG1611	Belongs to the LOG family
EHC64_13195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC64_13205	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EHC64_13210	COG2363	Small membrane protein
EHC64_13220	COG0583	DNA-binding transcription factor activity
EHC64_13225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC64_13225	COG0301	tRNA thio-modification
EHC64_13230	COG2885	chlorophyll binding
EHC64_13235	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC64_13240	COG1722	exodeoxyribonuclease VII activity
EHC64_13245	COG0142	geranyltranstransferase activity
EHC64_13250	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHC64_13255	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EHC64_13260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EHC64_13265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC64_13285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC64_13285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC64_13290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHC64_13295	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHC64_13300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHC64_13315	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EHC64_13320	COG2252	PERMEase
EHC64_13325	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC64_13350	COG0047	phosphoribosylformylglycinamidine synthase activity
EHC64_13350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHC64_13355	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EHC64_13365	COG0590	tRNA wobble adenosine to inosine editing
EHC64_13370	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC64_13410	COG0484	heat shock protein binding
EHC64_13415	COG0443	Heat shock 70 kDa protein
EHC64_13425	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHC64_13430	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHC64_13440	COG0497	DNA recombination
EHC64_13445	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC64_13450	COG2914	Belongs to the UPF0125 (RnfH) family
EHC64_13455	COG2867	negative regulation of translational initiation
EHC64_13460	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHC64_13470	COG0582	viral genome integration into host DNA
EHC64_13485	COG0270	DNA (cytosine-5-)-methyltransferase activity
EHC64_13520	COG1278	Cold shock
EHC64_13535	COG1278	Cold shock
EHC64_13630	COG0583	DNA-binding transcription factor activity
EHC64_13635	COG3153	acetyltransferase
EHC64_13635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC64_13655	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC64_13660	COG2873	o-acetylhomoserine
EHC64_13700	COG1115	amino acid carrier protein
EHC64_13710	COG1584	GPR1 FUN34 yaaH family protein
EHC64_13720	COG1757	Na H antiporter
EHC64_13725	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EHC64_13725	COG0519	Catalyzes the synthesis of GMP from XMP
EHC64_13730	COG0516	GMP reductase activity
EHC64_13730	COG0517	IMP dehydrogenase activity
EHC64_13735	COG1570	exodeoxyribonuclease VII activity
EHC64_13750	COG1160	GTP binding
EHC64_13755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC64_13760	COG2976	Protein conserved in bacteria
EHC64_13765	COG0124	histidyl-tRNA synthetase
EHC64_13770	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHC64_13785	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EHC64_13790	COG0105	UTP biosynthetic process
EHC64_13795	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC64_13800	COG2975	iron-sulfur cluster assembly
EHC64_13805	COG0633	Ferredoxin
EHC64_13810	COG0443	Heat shock 70 kDa protein
EHC64_13815	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC64_13825	COG0822	iron-sulfur transferase activity
EHC64_13830	COG1104	cysteine desulfurase activity
EHC64_13845	COG0483	inositol monophosphate 1-phosphatase activity
EHC64_13855	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC64_13860	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC64_13865	COG1862	Preprotein translocase
EHC64_13870	COG0343	queuine tRNA-ribosyltransferase activity
EHC64_13875	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EHC64_13890	COG0517	IMP dehydrogenase activity
EHC64_13900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EHC64_13910	COG0583	DNA-binding transcription factor activity
EHC64_13915	COG0450	alkyl hydroperoxide reductase
EHC64_13925	COG3142	Participates in the control of copper homeostasis
EHC64_13935	COG0704	Plays a role in the regulation of phosphate uptake
EHC64_13940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC64_13945	COG0581	inorganic phosphate transmembrane transporter activity
EHC64_13955	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EHC64_13960	COG0248	Ppx GppA phosphatase
EHC64_13970	COG5002	protein histidine kinase activity
EHC64_13975	COG0745	RESPONSE REGULATOR receiver
EHC64_13985	COG2974	May be involved in recombination
EHC64_13995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHC64_14055	COG0542	response to heat
EHC64_14065	COG0564	pseudouridine synthase activity
EHC64_14070	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC64_14075	COG0741	lytic transglycosylase activity
EHC64_14080	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC64_14085	COG1605	Chorismate mutase
EHC64_14085	COG0077	Prephenate dehydratase
EHC64_14090	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EHC64_14095	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EHC64_14105	COG0488	(ABC) transporter
EHC64_14120	COG0739	heme binding
EHC64_14125	COG1605	Chorismate mutase
EHC64_14125	COG0287	Prephenate dehydrogenase
EHC64_14130	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC64_14135	COG1472	Belongs to the glycosyl hydrolase 3 family
EHC64_14140	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EHC64_14145	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC64_14160	COG1966	Carbon starvation protein
EHC64_14165	COG3275	phosphorelay sensor kinase activity
EHC64_14170	COG3279	Response regulator of the LytR AlgR family
EHC64_14175	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHC64_14180	COG1047	Peptidyl-prolyl cis-trans
EHC64_14185	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHC64_14190	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC64_14195	COG0196	riboflavin kinase activity
EHC64_14200	COG0728	peptidoglycan biosynthetic process
EHC64_14205	COG0268	Binds directly to 16S ribosomal RNA
EHC64_14215	COG0640	Transcriptional regulator
EHC64_14225	COG0583	DNA-binding transcription factor activity
EHC64_14230	COG1283	sodium-dependent phosphate transmembrane transporter activity
EHC64_14240	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHC64_14245	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHC64_14250	COG0730	response to heat
EHC64_14260	COG0494	nUDIX hydrolase
EHC64_14270	COG3066	DNA modification
EHC64_14280	COG0667	Aldo Keto reductase
EHC64_14295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EHC64_14305	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EHC64_14310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC64_14320	COG0716	FMN binding
EHC64_14330	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EHC64_14335	COG0513	Belongs to the DEAD box helicase family
EHC64_14340	COG3022	response to hydroperoxide
EHC64_14345	COG1115	amino acid carrier protein
EHC64_14360	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EHC64_14370	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EHC64_14375	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EHC64_14380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EHC64_14385	COG0083	homoserine kinase activity
EHC64_14400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC64_14415	COG0745	RESPONSE REGULATOR receiver
EHC64_14425	COG2198	Histidine kinase
EHC64_14425	COG0784	Response regulator, receiver
EHC64_14425	COG5002	protein histidine kinase activity
EHC64_14430	COG2203	Gaf domain
EHC64_14430	COG4251	negative regulation of phosphorylation
EHC64_14430	COG5001	Diguanylate cyclase
EHC64_14430	COG3706	GGDEF domain
EHC64_14435	COG1242	4 iron, 4 sulfur cluster binding
EHC64_14440	COG0069	glutamate synthase activity
EHC64_14440	COG0070	glutamate synthase
EHC64_14440	COG0067	glutamate synthase
EHC64_14450	COG0067	glutamate synthase
EHC64_14450	COG0069	glutamate synthase activity
EHC64_14450	COG0070	glutamate synthase
EHC64_14455	COG0493	'glutamate synthase
EHC64_14465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC64_14475	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC64_14480	COG2860	membrane
EHC64_14485	COG0583	DNA-binding transcription factor activity
EHC64_14490	COG0730	response to heat
EHC64_14505	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EHC64_14510	COG0505	Belongs to the CarA family
EHC64_14515	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EHC64_14520	COG0494	nUDIX hydrolase
EHC64_14525	COG0653	protein targeting
EHC64_14535	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EHC64_14540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHC64_14545	COG0849	cell division
EHC64_14550	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EHC64_14555	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC64_14560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHC64_14565	COG0772	Belongs to the SEDS family
EHC64_14570	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHC64_14575	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHC64_14580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EHC64_14585	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHC64_14590	COG0768	penicillin binding
EHC64_14595	COG3116	cell division
EHC64_14600	COG0275	rRNA processing
EHC64_14615	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHC64_14625	COG0792	nuclease activity
EHC64_14630	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC64_14635	COG2823	Periplasmic or secreted lipoprotein
EHC64_14640	COG2969	positive regulation of protein catabolic process
EHC64_14645	COG0625	glutathione transferase activity
EHC64_14650	COG2857	Cytochrome c1
EHC64_14655	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EHC64_14660	COG0723	plastoquinol--plastocyanin reductase activity
EHC64_14665	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EHC64_14670	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHC64_14680	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EHC64_14690	COG3105	Protein conserved in bacteria
EHC64_14700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHC64_14705	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHC64_14710	COG0187	DNA topoisomerase II activity
EHC64_14715	COG3150	esterase
EHC64_14725	COG3151	Protein conserved in bacteria
EHC64_14730	COG0494	nUDIX hydrolase
EHC64_14735	COG1538	Outer membrane efflux protein
EHC64_14740	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EHC64_14740	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EHC64_14745	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EHC64_14760	COG3025	triphosphatase activity
EHC64_14765	COG1392	Phosphate transport regulator
EHC64_14770	COG0306	phosphate transporter
EHC64_14775	COG4991	sh3 domain protein
EHC64_14785	COG3267	Type II secretory pathway component ExeA
EHC64_14785	COG3409	Peptidoglycan-binding domain 1 protein
EHC64_14790	COG0617	tRNA 3'-terminal CCA addition
EHC64_14795	COG1968	undecaprenyl-diphosphatase activity
EHC64_14800	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHC64_14805	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHC64_14810	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EHC64_14815	COG0596	Alpha beta hydrolase
EHC64_14820	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHC64_14825	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EHC64_14830	COG1610	YqeY-like protein
EHC64_14835	COG0358	DNA primase activity
EHC64_14840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHC64_14900	COG0582	viral genome integration into host DNA
EHC64_14985	COG0582	viral genome integration into host DNA
EHC64_14990	COG0326	Molecular chaperone. Has ATPase activity
EHC64_15010	COG2003	Belongs to the UPF0758 family
EHC64_15035	COG1464	Belongs to the NlpA lipoprotein family
EHC64_15070	COG2213	PTS system mannitol-specific
EHC64_15070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_15075	COG0246	Mannitol dehydrogenase
EHC64_15080	COG3722	fumarate hydratase activity
EHC64_15095	COG1461	Dihydroxyacetone kinase
EHC64_15100	COG2376	Dihydroxyacetone kinase
EHC64_15110	COG5002	protein histidine kinase activity
EHC64_15125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EHC64_15130	COG1349	DNA-binding transcription factor activity
EHC64_15140	COG0469	pyruvate kinase activity
EHC64_15150	COG3706	GGDEF domain
EHC64_15155	COG0440	acetolactate synthase activity
EHC64_15160	COG0028	Belongs to the TPP enzyme family
EHC64_15165	COG1022	Amp-dependent synthetase and ligase
EHC64_15170	COG0583	DNA-binding transcription factor activity
EHC64_15190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHC64_15195	COG0473	3-isopropylmalate dehydrogenase activity
EHC64_15200	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHC64_15205	COG0066	3-isopropylmalate dehydratase activity
EHC64_15215	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC64_15220	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EHC64_15225	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC64_15230	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EHC64_15235	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EHC64_15240	COG2967	ApaG domain
EHC64_15245	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EHC64_15260	COG2966	Psort location CytoplasmicMembrane, score
EHC64_15265	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHC64_15275	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EHC64_15280	COG0142	geranyltranstransferase activity
EHC64_15290	COG0039	L-malate dehydrogenase activity
EHC64_15325	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EHC64_15330	COG1178	ABC-type Fe3 transport system permease component
EHC64_15335	COG4143	(ABC) transporter
EHC64_15340	COG0163	prenyltransferase activity
EHC64_15345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC64_15355	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EHC64_15360	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EHC64_15370	COG2105	PFAM AIG2 family protein
EHC64_15380	COG0729	surface antigen
EHC64_15385	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC64_15395	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC64_15410	COG4181	ATPase activity
EHC64_15430	COG0529	Catalyzes the synthesis of activated sulfate
EHC64_15435	COG0471	metal ion transport
EHC64_15435	COG3273	potassium ion transport
EHC64_15445	COG2895	sulfate adenylyltransferase (ATP) activity
EHC64_15450	COG0175	sulfate reduction
EHC64_15455	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHC64_15455	COG1648	precorrin-2 dehydrogenase activity
EHC64_15460	COG0737	Belongs to the 5'-nucleotidase family
EHC64_15470	COG0513	Belongs to the DEAD box helicase family
EHC64_15475	COG2153	protein acetylation
EHC64_15485	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC64_15495	COG0203	ribosomal protein L17
EHC64_15500	COG0202	RNA polymerase activity
EHC64_15510	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHC64_15515	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHC64_15525	COG0201	protein transport
EHC64_15530	COG0200	Binds to the 23S rRNA
EHC64_15535	COG1841	ribosomal large subunit assembly
EHC64_15550	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHC64_15555	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHC64_15560	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHC64_15565	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHC64_15570	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHC64_15575	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHC64_15580	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHC64_15585	COG0255	Belongs to the universal ribosomal protein uL29 family
EHC64_15595	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHC64_15600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHC64_15605	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHC64_15610	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHC64_15620	COG0088	Forms part of the polypeptide exit tunnel
EHC64_15625	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHC64_15635	COG0254	rRNA binding
EHC64_15645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHC64_15650	COG1609	Transcriptional regulator
EHC64_15660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EHC64_15665	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EHC64_15670	COG1575	Belongs to the MenA family. Type 1 subfamily
EHC64_15675	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC64_15680	COG3074	FtsZ-dependent cytokinesis
EHC64_15690	COG1494	fructose-1,6-bisphosphatase
EHC64_15715	COG0149	triose-phosphate isomerase activity
EHC64_15740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC64_15750	COG0438	transferase activity, transferring glycosyl groups
EHC64_15775	COG0438	transferase activity, transferring glycosyl groups
EHC64_15835	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC64_15845	COG1560	Kdo2-lipid A biosynthetic process
EHC64_15850	COG0859	PFAM glycosyl transferase family 9
EHC64_15855	COG1519	Transferase
EHC64_15875	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_15885	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHC64_15900	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC64_15910	COG2089	acid synthase
EHC64_15915	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EHC64_15920	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EHC64_15930	COG3642	lipopolysaccharide core region biosynthetic process
EHC64_15935	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC64_15940	COG0859	PFAM glycosyl transferase family 9
EHC64_15945	COG0463	Glycosyl transferase, family 2
EHC64_15960	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHC64_15965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EHC64_15975	COG2194	sulfuric ester hydrolase activity
EHC64_15985	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EHC64_15990	COG2003	Belongs to the UPF0758 family
EHC64_16005	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHC64_16010	COG1309	transcriptional regulator
EHC64_16015	COG1560	Kdo2-lipid A biosynthetic process
EHC64_16020	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EHC64_16025	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHC64_16030	COG1561	YicC-like family, N-terminal region
EHC64_16040	COG4608	Belongs to the ABC transporter superfamily
EHC64_16045	COG0444	Belongs to the ABC transporter superfamily
EHC64_16050	COG0747	negative chemotaxis
EHC64_16055	COG4239	(ABC) transporter, permease
EHC64_16060	COG4174	ABC transporter (Permease)
EHC64_16085	COG0811	peptide transport
EHC64_16090	COG0848	biopolymer transport protein
EHC64_16105	COG0194	GDP metabolic process
EHC64_16110	COG1758	RNA polymerase activity
EHC64_16115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC64_16120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC64_16125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHC64_16135	COG2233	PERMEase
EHC64_16140	COG2205	protein histidine kinase activity
EHC64_16145	COG0745	RESPONSE REGULATOR receiver
EHC64_16155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC64_16165	COG2183	response to ionizing radiation
EHC64_16175	COG0596	Alpha beta hydrolase
EHC64_16180	COG1040	competence protein
EHC64_16185	COG0316	Belongs to the HesB IscA family
EHC64_16185	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EHC64_16190	COG0494	nUDIX hydrolase
EHC64_16195	COG1218	3'(2'),5'-bisphosphate nucleotidase
EHC64_16205	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC64_16210	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC64_16215	COG3156	type II secretion system protein K
EHC64_16220	COG4795	General secretion pathway protein
EHC64_16225	COG2165	general secretion pathway protein
EHC64_16230	COG2165	general secretion pathway protein
EHC64_16235	COG2165	general secretion pathway protein
EHC64_16240	COG1459	type II secretion system
EHC64_16245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC64_16255	COG3031	protein transport across the cell outer membrane
EHC64_16260	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EHC64_16265	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHC64_16270	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EHC64_16280	COG0456	acetyltransferase
EHC64_16285	COG1490	D-aminoacyl-tRNA deacylase activity
EHC64_16290	COG1295	ribonuclease BN
EHC64_16310	COG0174	glutamine synthetase
EHC64_16320	COG3852	Histidine kinase
EHC64_16325	COG2204	response regulator
EHC64_16335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC64_16340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC64_16375	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EHC64_16385	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC64_16385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC64_16410	COG0084	hydrolase, TatD family'
EHC64_16420	COG0805	protein transport
EHC64_16430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHC64_16435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC64_16440	COG3165	ubiquinone biosynthetic process from chorismate
EHC64_16445	COG2226	methyltransferase
EHC64_16450	COG1322	Protein conserved in bacteria
EHC64_16465	COG0628	permease
EHC64_16515	COG2823	Periplasmic or secreted lipoprotein
EHC64_16525	COG2081	HI0933 family
EHC64_16535	COG1528	Iron-storage protein
EHC64_16540	COG0589	response to stress
EHC64_16545	COG0697	spore germination
EHC64_16555	COG0742	ribosomal rna small subunit methyltransferase
EHC64_16560	COG5002	protein histidine kinase activity
EHC64_16560	COG5001	Diguanylate cyclase
EHC64_16565	COG1522	sequence-specific DNA binding
EHC64_16570	COG0339	signal peptide processing
EHC64_16580	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EHC64_16585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC64_16590	COG0583	DNA-binding transcription factor activity
EHC64_16595	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EHC64_16600	COG0800	Aldolase
EHC64_16605	COG2610	gluconate transmembrane transporter activity
EHC64_16610	COG3265	gluconokinase activity
EHC64_16615	COG0129	dihydroxy-acid dehydratase activity
EHC64_16620	COG2076	Multidrug Resistance protein
EHC64_16630	COG0583	DNA-binding transcription factor activity
EHC64_16635	COG1609	Transcriptional regulator
EHC64_16675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC64_16685	COG0747	negative chemotaxis
EHC64_16690	COG4172	Belongs to the ABC transporter superfamily
EHC64_16755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_16760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_16770	COG2960	long-chain fatty acid transporting porin activity
EHC64_16775	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHC64_16780	COG0583	DNA-binding transcription factor activity
EHC64_16825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EHC64_16835	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHC64_16840	COG0408	coproporphyrinogen oxidase activity
EHC64_16845	COG0009	L-threonylcarbamoyladenylate synthase
EHC64_16850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHC64_16855	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EHC64_16860	COG0551	DNA topoisomerase type I activity
EHC64_16865	COG2922	Belongs to the Smg family
EHC64_16870	COG0758	DNA mediated transformation
EHC64_16880	COG0242	peptide deformylase activity
EHC64_16885	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHC64_16890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC64_16890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC64_16895	COG0569	domain protein
EHC64_16900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC64_16910	COG1272	protein, Hemolysin III
EHC64_16915	COG4326	sporulation control protein
EHC64_16925	COG3084	Protein conserved in bacteria
EHC64_16935	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EHC64_16940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC64_16945	COG0204	Acyl-transferase
EHC64_17040	COG0606	chelatase, subunit chli
EHC64_17050	COG3978	acetolactate synthase activity
EHC64_17055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EHC64_17060	COG0129	dihydroxy-acid dehydratase activity
EHC64_17070	COG0583	DNA-binding transcription factor activity
EHC64_17075	COG2814	Major facilitator Superfamily
EHC64_17080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_17085	COG0765	amino acid transport
EHC64_17090	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHC64_17095	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EHC64_17100	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHC64_17105	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHC64_17110	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHC64_17115	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHC64_17130	COG0356	it plays a direct role in the translocation of protons across the membrane
EHC64_17135	COG3312	ion transport
EHC64_17140	COG1475	DNA binding
EHC64_17145	COG1192	Involved in chromosome partitioning
EHC64_17150	COG0357	Ribosomal RNA small subunit methyltransferase G
EHC64_17155	COG0445	tRNA wobble uridine modification
EHC64_17160	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHC64_17165	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHC64_17170	COG0706	membrane insertase activity
EHC64_17175	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EHC64_17180	COG0594	ribonuclease P activity
EHC64_17190	COG1126	abc transporter atp-binding protein
EHC64_17215	COG2304	oxidoreductase activity
EHC64_17230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC64_17235	COG0581	inorganic phosphate transmembrane transporter activity
EHC64_17240	COG0573	inorganic phosphate transmembrane transporter activity
EHC64_17245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC64_17270	COG4771	TonB-dependent receptor
EHC64_17275	COG1770	oligopeptidase
EHC64_17280	COG0513	Belongs to the DEAD box helicase family
EHC64_17290	COG1376	ErfK ybiS ycfS ynhG family protein
EHC64_17290	COG1388	LysM domain
EHC64_17295	COG0415	Belongs to the DNA photolyase family
EHC64_17300	COG0789	Transcriptional regulator
EHC64_17305	COG3272	Protein of unknown function (DUF1722)
EHC64_17315	COG0813	purine-nucleoside phosphorylase activity
EHC64_17330	COG3706	GGDEF domain
EHC64_17340	COG1566	PFAM secretion protein HlyD family protein
EHC64_17345	COG4720	Psort location CytoplasmicMembrane, score
EHC64_17350	COG1122	ATPase activity
EHC64_17365	COG0348	domain, Protein
EHC64_17370	COG0437	4 iron, 4 sulfur cluster binding
EHC64_17375	COG1247	-acetyltransferase
EHC64_17405	COG1067	ATP-dependent peptidase activity
EHC64_17415	COG4172	Belongs to the ABC transporter superfamily
EHC64_17420	COG1505	serine-type exopeptidase activity
EHC64_17425	COG0583	DNA-binding transcription factor activity
EHC64_17430	COG1620	l-lactate permease
EHC64_17435	COG1304	FMN binding
EHC64_17445	COG0668	transmembrane transport
EHC64_17485	COG1063	alcohol dehydrogenase
EHC64_17490	COG0156	8-amino-7-oxononanoate synthase activity
EHC64_17500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_17520	COG0745	RESPONSE REGULATOR receiver
EHC64_17555	COG0346	lactoylglutathione lyase activity
EHC64_17575	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC64_17615	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC64_17630	COG2204	response regulator
EHC64_17655	COG1987	bacterial-type flagellum assembly
EHC64_17665	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHC64_17680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_17690	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHC64_17695	COG1516	flagellar protein fliS
EHC64_17710	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC64_17715	COG1191	sigma factor activity
EHC64_17720	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC64_17725	COG1360	Flagellar Motor Protein
EHC64_17760	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC64_17765	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC64_17775	COG0454	-acetyltransferase
EHC64_17785	COG2814	Major facilitator Superfamily
EHC64_17830	COG0628	permease
EHC64_17835	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC64_17845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC64_17855	COG4628	conserved protein (DUF2132)
EHC64_17860	COG0583	DNA-binding transcription factor activity
EHC64_17885	COG1686	Belongs to the peptidase S11 family
EHC64_17905	COG3397	chitin binding
EHC64_17910	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC64_17915	COG2095	MarC family integral membrane protein
EHC64_17935	COG3206	protein involved in exopolysaccharide biosynthesis
EHC64_17935	COG0489	protein tyrosine kinase activity
EHC64_17950	COG0583	DNA-binding transcription factor activity
EHC64_17960	COG1301	dicarboxylic acid transport
EHC64_17975	COG3339	Conserved Protein
EHC64_17980	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC64_17985	COG0700	Nucleoside recognition
EHC64_17990	COG3366	ferrous iron transmembrane transporter activity
EHC64_18005	COG0366	Alpha amylase catalytic
EHC64_18010	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC64_18015	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EHC64_18020	COG1640	4-alpha-glucanotransferase
EHC64_18025	COG0058	SHG alpha-glucan phosphorylase activity
EHC64_18040	COG2909	trisaccharide binding
EHC64_18055	COG1999	signal sequence binding
EHC64_18065	COG1263	PTS System
EHC64_18065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC64_18070	COG1162	GTPase activity
EHC64_18075	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EHC64_18085	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC64_18100	COG0531	amino acid
EHC64_18105	COG1982	Orn Lys Arg decarboxylase major
EHC64_18125	COG2356	endonuclease I
EHC64_18150	COG4580	involved in the transport of maltose and maltodextrins
EHC64_18175	COG0739	heme binding
EHC64_18185	COG0612	Peptidase, M16
EHC64_18190	COG0840	transmembrane signaling receptor activity
EHC64_18195	COG1120	ATPase activity
EHC64_18200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC64_18205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC64_18210	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC64_18215	COG4772	TonB-dependent receptor
EHC64_18240	COG4264	IucA IucC family
EHC64_18245	COG0019	diaminopimelate decarboxylase activity
EHC64_18250	COG1653	transport
EHC64_18260	COG0745	RESPONSE REGULATOR receiver
EHC64_18285	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC64_18290	COG1129	ABC transporter
EHC64_18295	COG1879	ABC-type sugar transport system periplasmic component
EHC64_18300	COG1069	ribulokinase activity
EHC64_18310	COG2160	L-arabinose isomerase activity
EHC64_18335	COG1764	response to oxidative stress
EHC64_18340	COG1846	Transcriptional regulator
EHC64_18345	COG0450	alkyl hydroperoxide reductase
EHC64_18350	COG3634	alkyl hydroperoxide reductase activity
EHC64_18400	COG0840	transmembrane signaling receptor activity
EHC64_18405	COG0583	DNA-binding transcription factor activity
EHC64_18410	COG1486	melibiose metabolic process
EHC64_18425	COG2258	MOSC domain
EHC64_18430	COG0513	Belongs to the DEAD box helicase family
EHC64_18440	COG2186	Transcriptional regulator
EHC64_18450	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC64_18460	COG0246	Mannitol dehydrogenase
EHC64_18465	COG1904	glucuronate isomerase
EHC64_18470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC64_18475	COG0800	Aldolase
EHC64_18500	COG2207	Transcriptional regulator
EHC64_18510	COG1132	(ABC) transporter
EHC64_18555	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC64_18585	COG0259	pyridoxamine-phosphate oxidase activity
EHC64_18630	COG4166	transmembrane transport
EHC64_18650	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC64_18655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC64_18655	COG1263	PTS System
EHC64_18660	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC64_18665	COG3340	Belongs to the peptidase S51 family
EHC64_18685	COG1444	tRNA N-acetyltransferase activity
EHC64_18710	COG4608	Belongs to the ABC transporter superfamily
EHC64_18715	COG0444	Belongs to the ABC transporter superfamily
EHC64_18725	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC64_18725	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EHC64_18750	COG0217	transcriptional regulatory protein
EHC64_18755	COG0772	Belongs to the SEDS family
EHC64_18790	COG3275	phosphorelay sensor kinase activity
EHC64_18795	COG3279	Response regulator of the LytR AlgR family
EHC64_18805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC64_18840	COG0786	glutamate:sodium symporter activity
EHC64_18850	COG1131	(ABC) transporter
EHC64_18855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC64_18860	COG0786	glutamate:sodium symporter activity
EHC64_18875	COG0363	glucosamine-6-phosphate deaminase activity
EHC64_18895	COG1741	Belongs to the pirin family
EHC64_18900	COG2259	Doxx family
EHC64_18915	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EHC64_18920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHC64_18930	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC64_18970	COG3123	guanosine phosphorylase activity
EHC64_18980	COG5001	Diguanylate cyclase
EHC64_18990	COG0534	Mate efflux family protein
EHC64_18995	COG0564	pseudouridine synthase activity
EHC64_19010	COG0583	DNA-binding transcription factor activity
EHC64_19015	COG0561	phosphatase activity
EHC64_19025	COG2199	diguanylate cyclase activity
EHC64_19040	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EHC64_19045	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EHC64_19050	COG0583	DNA-binding transcription factor activity
EHC64_19065	COG1414	Transcriptional regulator
EHC64_19070	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_19080	COG1917	Cupin 2, conserved barrel domain protein
EHC64_19095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC64_19100	COG0800	Aldolase
EHC64_19120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC64_19125	COG0823	Involved in the tonB-independent uptake of proteins
EHC64_19130	COG2375	cellular response to nickel ion
EHC64_19160	COG1357	PFAM Pentapeptide repeats (8 copies)
EHC64_19165	COG3047	cAMP biosynthetic process
EHC64_19195	COG3408	Glycogen debranching enzyme
EHC64_19195	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EHC64_19200	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EHC64_19210	COG0583	DNA-binding transcription factor activity
EHC64_19220	COG0583	DNA-binding transcription factor activity
EHC64_19235	COG0546	phosphoglycolate phosphatase activity
EHC64_19260	COG3835	regulator
EHC64_19265	COG2610	gluconate transmembrane transporter activity
EHC64_19270	COG1929	Belongs to the glycerate kinase type-1 family
EHC64_19275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC64_19310	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_19320	COG3005	denitrification pathway
EHC64_19325	COG0243	molybdopterin cofactor binding
EHC64_19335	COG0352	thiamine-phosphate diphosphorylase activity
EHC64_19340	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHC64_19345	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EHC64_19350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC64_19355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC64_19360	COG1116	anion transmembrane transporter activity
EHC64_19365	COG0351	phosphomethylpyrimidine kinase
EHC64_19375	COG0312	modulator of DNA gyrase
EHC64_19380	COG0312	modulator of DNA gyrase
EHC64_19385	COG1901	pseudouridine methyltransferase
EHC64_19450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC64_19460	COG0584	glycerophosphoryl diester phosphodiesterase
EHC64_19470	COG0745	RESPONSE REGULATOR receiver
EHC64_19490	COG0811	peptide transport
EHC64_19495	COG0811	peptide transport
EHC64_19500	COG0848	biopolymer transport protein
EHC64_19545	COG0803	Belongs to the bacterial solute-binding protein 9 family
EHC64_19550	COG1121	(ABC) transporter
EHC64_19555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC64_19570	COG1770	oligopeptidase
EHC64_19575	COG2814	Major facilitator Superfamily
EHC64_19580	COG0010	Belongs to the arginase family
EHC64_19585	COG1166	arginine decarboxylase activity
EHC64_19595	COG0189	ligase activity
EHC64_19595	COG4067	protein conserved in archaea
EHC64_19600	COG0189	ligase activity
EHC64_19605	COG0583	DNA-binding transcription factor activity
EHC64_19655	COG3706	GGDEF domain
EHC64_19685	COG0579	oxidoreductase
EHC64_19695	COG3033	Beta-eliminating lyase
EHC64_19715	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC64_19730	COG3706	GGDEF domain
EHC64_19735	COG0840	transmembrane signaling receptor activity
EHC64_19750	COG3706	GGDEF domain
EHC64_19755	COG0415	Belongs to the DNA photolyase family
EHC64_19760	COG3046	protein related to deoxyribodipyrimidine photolyase
EHC64_19775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC64_19775	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC64_19780	COG1765	OsmC-like protein
EHC64_19785	COG0110	maltose O-acetyltransferase activity
EHC64_19825	COG1011	Hydrolase
EHC64_19840	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC64_19850	COG2067	long-chain fatty acid transport protein
EHC64_19870	COG3240	lipase activity
EHC64_19895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_19900	COG1609	Transcriptional regulator
EHC64_19905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC64_19920	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC64_19930	COG3842	ATPase activity
EHC64_19955	COG2990	Protein conserved in bacteria
EHC64_19965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC64_19970	COG2866	Carboxypeptidase
EHC64_19985	COG0583	DNA-binding transcription factor activity
EHC64_20010	COG1760	l-serine dehydratase
EHC64_20030	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC64_20035	COG0741	lytic transglycosylase activity
EHC64_20055	COG1815	bacterial-type flagellum-dependent cell motility
EHC64_20060	COG1558	bacterial-type flagellum-dependent cell motility
EHC64_20065	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC64_20070	COG1749	Flagellar hook protein flgE
EHC64_20075	COG4787	bacterial-type flagellum-dependent cell motility
EHC64_20080	COG4786	Flagellar basal body rod
EHC64_20085	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC64_20090	COG1706	bacterial-type flagellum-dependent cell motility
EHC64_20100	COG4786	Flagellar basal body rod
EHC64_20100	COG1256	bacterial-type flagellum assembly
EHC64_20105	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC64_20125	COG1304	FMN binding
EHC64_20155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC64_20160	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC64_20165	COG0459	protein refolding
EHC64_20180	COG1280	lysine exporter protein (LysE YggA)
EHC64_20200	COG1309	transcriptional regulator
EHC64_20210	COG0737	Belongs to the 5'-nucleotidase family
EHC64_20215	COG2070	2-Nitropropane dioxygenase
EHC64_20220	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_20230	COG0583	DNA-binding transcription factor activity
EHC64_20245	COG0346	lactoylglutathione lyase activity
EHC64_20250	COG1349	DNA-binding transcription factor activity
EHC64_20260	COG0753	catalase activity
EHC64_20270	COG1335	isochorismatase
EHC64_20280	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EHC64_20305	COG0583	DNA-binding transcription factor activity
EHC64_20320	COG3713	MltA-interacting MipA family protein
EHC64_20330	COG3015	lipoprotein NlpE involved in copper resistance
EHC64_20340	COG1342	Belongs to the UPF0251 family
EHC64_20365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC64_20375	COG4948	Mandelate Racemase Muconate Lactonizing
EHC64_20385	COG0583	DNA-binding transcription factor activity
EHC64_20435	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC64_20475	COG3842	ATPase activity
EHC64_20505	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC64_20525	COG3706	GGDEF domain
EHC64_20545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_20560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC64_20565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC64_20585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC64_20585	COG0574	Belongs to the PEP-utilizing enzyme family
EHC64_20590	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EHC64_20595	COG0252	asparaginase activity
EHC64_20605	COG0583	DNA-binding transcription factor activity
EHC64_20620	COG3122	Protein conserved in bacteria
EHC64_20635	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_20645	COG1063	alcohol dehydrogenase
EHC64_20650	COG1902	pentaerythritol trinitrate reductase activity
EHC64_20665	COG0583	DNA-binding transcription factor activity
EHC64_20675	COG0513	Belongs to the DEAD box helicase family
EHC64_20690	COG3423	Transcriptional regulator
EHC64_20695	COG2801	Transposase and inactivated derivatives
EHC64_20705	COG2842	Transposition protein
EHC64_20785	COG5566	PFAM Mor transcription activator
EHC64_20815	COG0640	Transcriptional regulator
EHC64_20825	COG4373	Mu-like prophage FluMu protein gp28
EHC64_20830	COG4383	Mu-like prophage protein gp29
EHC64_20850	COG4388	Caudovirus prohead serine protease
EHC64_20860	COG4397	Mu-like prophage major head subunit gpT
EHC64_20870	COG4387	Mu-like prophage protein GP36
EHC64_20970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC64_20975	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC64_20975	COG2207	Transcriptional regulator
EHC64_21005	COG2354	Protein conserved in bacteria
EHC64_21010	COG0418	dihydroorotase activity
EHC64_21020	COG0401	homolog of Blt101
EHC64_21030	COG0633	Ferredoxin
EHC64_21030	COG3217	Mosc domain protein beta barrel domain protein
EHC64_21030	COG0633	Ferredoxin
EHC64_21030	COG3217	Mosc domain protein beta barrel domain protein
EHC64_21035	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EHC64_21040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHC64_21085	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EHC64_21090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC64_21100	COG0848	biopolymer transport protein
EHC64_21105	COG0811	peptide transport
EHC64_21110	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EHC64_21120	COG3721	Heme iron utilization protein
EHC64_21125	COG0748	coenzyme F420 binding
EHC64_21135	COG0835	chemotaxis
EHC64_21135	COG0784	Response regulator, receiver
EHC64_21145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC64_21180	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC64_21185	COG0783	Belongs to the Dps family
EHC64_21195	COG0583	DNA-binding transcription factor activity
EHC64_21215	COG0641	radical SAM
EHC64_21230	COG4934	collagen metabolic process
EHC64_21240	COG0366	Alpha amylase catalytic
EHC64_21260	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC64_21265	COG0589	response to stress
EHC64_21270	COG0488	(ABC) transporter
EHC64_21275	COG1505	serine-type exopeptidase activity
EHC64_21285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC64_21295	COG2067	long-chain fatty acid transport protein
EHC64_21305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC64_21315	COG2199	diguanylate cyclase activity
EHC64_21315	COG2203	Gaf domain
EHC64_21335	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_21360	COG3383	formate dehydrogenase (NAD+) activity
EHC64_21375	COG0842	Transport permease protein
EHC64_21380	COG1131	(ABC) transporter
EHC64_21390	COG0840	transmembrane signaling receptor activity
EHC64_21410	COG1881	PFAM PEBP family protein
EHC64_21420	COG0798	PFAM Bile acid sodium symporter
EHC64_21440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_21445	COG2213	PTS system mannitol-specific
EHC64_21450	COG1063	alcohol dehydrogenase
EHC64_21460	COG1072	(Pantothenic acid kinase))
EHC64_21465	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC64_21485	COG0814	amino acid
EHC64_21525	COG0739	heme binding
EHC64_21530	COG5001	Diguanylate cyclase
EHC64_21535	COG0583	DNA-binding transcription factor activity
EHC64_21540	COG2814	Major facilitator Superfamily
EHC64_21565	COG0697	spore germination
EHC64_21595	COG2207	Transcriptional regulator
EHC64_21600	COG1280	lysine exporter protein (LysE YggA)
EHC64_21610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC64_21615	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC64_21625	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EHC64_21650	COG1612	heme a metabolic process
EHC64_21655	COG0109	protoheme IX farnesyltransferase activity
EHC64_21660	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC64_21695	COG1278	Cold shock
EHC64_21700	COG3036	rescue of stalled ribosome
EHC64_21715	COG2199	diguanylate cyclase activity
EHC64_21735	COG0577	efflux transmembrane transporter activity
EHC64_21735	COG1136	(ABC) transporter
EHC64_21745	COG0840	transmembrane signaling receptor activity
EHC64_21755	COG0783	Belongs to the Dps family
EHC64_21765	COG2133	pyrroloquinoline quinone binding
EHC64_21770	COG1454	alcohol dehydrogenase
EHC64_21775	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EHC64_21815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC64_21820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC64_21825	COG3186	Phenylalanine-4-hydroxylase
EHC64_21830	COG2154	pterin-4-alpha-carbinolamine dehydratase
EHC64_21855	COG3530	Putative quorum-sensing-regulated virulence factor
EHC64_21860	COG0513	Belongs to the DEAD box helicase family
EHC64_21865	COG4628	conserved protein (DUF2132)
EHC64_21870	COG0133	tryptophan synthase activity
EHC64_21880	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EHC64_21890	COG0523	cobalamin synthesis protein
EHC64_21895	COG0513	Belongs to the DEAD box helicase family
EHC64_21915	COG2200	EAL domain
EHC64_21920	COG1119	ATPase activity
EHC64_21925	COG0840	transmembrane signaling receptor activity
EHC64_21950	COG0641	radical SAM
EHC64_21985	COG0582	viral genome integration into host DNA
EHC64_22030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC64_22045	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EHC64_22050	COG0513	Belongs to the DEAD box helicase family
EHC64_22055	COG5001	Diguanylate cyclase
EHC64_22065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC64_22080	COG5413	integral membrane protein
EHC64_22090	COG1024	Enoyl-CoA hydratase
EHC64_22095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHC64_22100	COG1960	acyl-CoA dehydrogenase activity
EHC64_22110	COG0183	Belongs to the thiolase family
EHC64_22125	COG1024	Enoyl-CoA hydratase
EHC64_22130	COG1024	Enoyl-CoA hydratase
EHC64_22145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC64_22150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHC64_22155	COG1845	cytochrome c oxidase, subunit III
EHC64_22160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EHC64_22165	COG0109	protoheme IX farnesyltransferase activity
EHC64_22180	COG1902	pentaerythritol trinitrate reductase activity
EHC64_22190	COG1126	abc transporter atp-binding protein
EHC64_22195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_22200	COG4215	(ABC) transporter
EHC64_22205	COG4160	amino acid transport
EHC64_22220	COG0625	glutathione transferase activity
EHC64_22260	COG0443	Heat shock 70 kDa protein
EHC64_22265	COG2847	Copper chaperone PCu(A)C
EHC64_22290	COG4607	ABC-type enterochelin transport system periplasmic component
EHC64_22295	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC64_22300	COG4605	iron ion homeostasis
EHC64_22305	COG4604	ABC transporter, ATP-binding protein
EHC64_22310	COG0789	Transcriptional regulator
EHC64_22325	COG4771	TonB-dependent receptor
EHC64_22325	COG1629	transport
EHC64_22360	COG1289	transmembrane transporter activity
EHC64_22365	COG0210	DNA helicase
EHC64_22370	COG1803	Methylglyoxal synthase
EHC64_22375	COG1879	ABC-type sugar transport system periplasmic component
EHC64_22380	COG0784	Response regulator, receiver
EHC64_22380	COG2205	protein histidine kinase activity
EHC64_22380	COG2198	Histidine kinase
EHC64_22395	COG0745	RESPONSE REGULATOR receiver
EHC64_22400	COG3119	arylsulfatase activity
EHC64_22405	COG3119	arylsulfatase activity
EHC64_22420	COG3119	arylsulfatase activity
EHC64_22425	COG0641	radical SAM
EHC64_22430	COG0714	Associated with various cellular activities
EHC64_22460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC64_22465	COG0583	DNA-binding transcription factor activity
EHC64_22470	COG1597	lipid kinase activity
EHC64_22475	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC64_22495	COG0641	radical SAM
EHC64_22525	COG0501	Belongs to the peptidase M48B family
EHC64_22530	COG1704	LemA family
EHC64_22535	COG3069	C4-dicarboxylate transmembrane transporter activity
EHC64_22545	COG0456	acetyltransferase
EHC64_22545	COG1214	PFAM Peptidase M22, glycoprotease
EHC64_22565	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EHC64_22605	COG4964	Belongs to the GSP D family
EHC64_22665	COG0583	DNA-binding transcription factor activity
EHC64_22670	COG0583	DNA-binding transcription factor activity
EHC64_22685	COG3300	MHYT domain
EHC64_22685	COG5001	Diguanylate cyclase
EHC64_22690	COG2197	response regulator
EHC64_22695	COG3706	GGDEF domain
EHC64_22705	COG2197	response regulator
EHC64_22730	COG0784	Response regulator, receiver
EHC64_22730	COG0835	chemotaxis
EHC64_22750	COG2962	Rard protein
EHC64_22765	COG0671	phosphoesterase, PA-phosphatase related
EHC64_22780	COG2076	Multidrug Resistance protein
EHC64_22810	COG0471	metal ion transport
EHC64_22815	COG3290	protein histidine kinase activity
EHC64_22820	COG4565	transcriptional regulatory protein
EHC64_22830	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC64_22830	COG0069	glutamate synthase activity
EHC64_22840	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC64_22865	COG1902	pentaerythritol trinitrate reductase activity
EHC64_22870	COG0346	lactoylglutathione lyase activity
EHC64_22890	COG2239	Acts as a magnesium transporter
EHC64_22920	COG0242	peptide deformylase activity
EHC64_22970	COG2176	DNA-directed DNA polymerase activity
EHC64_22975	COG0583	DNA-binding transcription factor activity
EHC64_22980	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC64_23020	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC64_23020	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC64_23025	COG0509	glycine decarboxylation via glycine cleavage system
EHC64_23030	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC64_23070	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_23070	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EHC64_23070	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_23075	COG1105	Belongs to the carbohydrate kinase PfkB family
EHC64_23080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_23080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_23085	COG1609	Transcriptional regulator
EHC64_23105	COG2199	diguanylate cyclase activity
EHC64_23105	COG2203	Gaf domain
EHC64_23105	COG2200	EAL domain
EHC64_23110	COG0765	amino acid transport
EHC64_23115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC64_23120	COG0765	amino acid transport
EHC64_23125	COG1126	abc transporter atp-binding protein
EHC64_23130	COG0469	pyruvate kinase activity
EHC64_23135	COG2271	Major facilitator Superfamily
EHC64_23140	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC64_23160	COG1979	alcohol dehydrogenase
EHC64_23165	COG2207	Transcriptional regulator
EHC64_23180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC64_23185	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EHC64_23190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC64_23210	COG0784	Response regulator, receiver
EHC64_23210	COG3437	response regulator, receiver
EHC64_23220	COG0546	phosphoglycolate phosphatase activity
EHC64_23230	COG0840	transmembrane signaling receptor activity
EHC64_23240	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EHC64_23245	COG0513	Belongs to the DEAD box helicase family
EHC64_23250	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EHC64_23265	COG3038	cytochrome b561
EHC64_23270	COG2353	YceI-like domain
EHC64_23275	COG2116	formate transmembrane transporter activity
EHC64_23280	COG0583	DNA-binding transcription factor activity
EHC64_23290	COG3593	DNA synthesis involved in DNA repair
EHC64_23295	COG0737	Belongs to the 5'-nucleotidase family
EHC64_23300	COG0861	Integral membrane protein TerC family
EHC64_23315	COG2267	carboxylic ester hydrolase activity
EHC64_23320	COG2067	long-chain fatty acid transport protein
EHC64_23335	COG2050	protein possibly involved in aromatic compounds catabolism
EHC64_23345	COG4533	DNA binding
EHC64_23370	COG0484	heat shock protein binding
EHC64_23380	COG3300	MHYT domain
EHC64_23380	COG5001	Diguanylate cyclase
EHC64_23385	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EHC64_23395	COG4181	ATPase activity
EHC64_23400	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EHC64_23410	COG1984	allophanate hydrolase subunit 2
EHC64_23415	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EHC64_23420	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EHC64_23425	COG3447	MASE1 domain protein
EHC64_23425	COG5002	protein histidine kinase activity
EHC64_23425	COG5001	Diguanylate cyclase
EHC64_23430	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHC64_23440	COG4771	TonB-dependent receptor
EHC64_23440	COG1629	transport
EHC64_23445	COG0583	DNA-binding transcription factor activity
EHC64_23450	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC64_23450	COG1042	CoA-binding domain protein
EHC64_23450	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC64_23460	COG1181	Belongs to the D-alanine--D-alanine ligase family
EHC64_23470	COG0023	Translation Initiation Factor
EHC64_23545	COG0583	DNA-binding transcription factor activity
EHC64_23555	COG0589	response to stress
EHC64_23560	COG3140	Belongs to the UPF0181 family
EHC64_23585	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EHC64_23590	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EHC64_23605	COG0745	RESPONSE REGULATOR receiver
EHC64_23605	COG3706	GGDEF domain
EHC64_23615	COG5001	Diguanylate cyclase
EHC64_23615	COG3706	GGDEF domain
EHC64_23615	COG2203	Gaf domain
EHC64_23615	COG4251	negative regulation of phosphorylation
EHC64_23625	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EHC64_23630	COG4149	molybdate abc transporter
EHC64_23635	COG0725	ABC transporter, periplasmic molybdate-binding protein
EHC64_23640	COG1492	cobalamin metabolic process
EHC64_23645	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC64_23655	COG0189	ligase activity
EHC64_23655	COG4067	protein conserved in archaea
EHC64_23675	COG0534	Mate efflux family protein
EHC64_23680	COG0602	queuosine metabolic process
EHC64_23685	COG1328	CTP reductase activity
EHC64_23700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC64_23725	COG0446	pyridine nucleotide-disulphide oxidoreductase
EHC64_23730	COG0243	molybdopterin cofactor binding
EHC64_23740	COG0583	DNA-binding transcription factor activity
EHC64_23745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC64_23755	COG2197	response regulator
EHC64_23760	COG3851	Histidine kinase
EHC64_23765	COG2271	Major facilitator Superfamily
EHC64_23790	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC64_23795	COG3118	belongs to the thioredoxin family
EHC64_23800	COG2814	Major facilitator Superfamily
EHC64_23810	COG0534	Mate efflux family protein
EHC64_23845	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC64_23865	COG2116	formate transmembrane transporter activity
EHC64_23870	COG2146	nitrite reductase [NAD(P)H] activity
EHC64_23875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC64_23880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC64_23925	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC64_23925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC64_23970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC64_23990	COG0277	FAD linked oxidase domain protein
EHC64_23995	COG0583	DNA-binding transcription factor activity
EHC64_24015	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EHC64_24030	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EHC64_24045	COG1288	antiporter activity
EHC64_24055	COG2814	Major facilitator Superfamily
EHC64_24065	COG3040	lipid binding
EHC64_24085	COG0419	ATPase involved in DNA repair
EHC64_24090	COG0420	3'-5' exonuclease activity
EHC64_24105	COG3501	Rhs element vgr protein
EHC64_24160	COG0631	protein serine/threonine phosphatase activity
EHC64_24200	COG2815	serine threonine protein kinase
EHC64_24200	COG0515	serine threonine protein kinase
EHC64_24255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC64_24255	COG2146	nitrite reductase [NAD(P)H] activity
EHC64_24260	COG1116	anion transmembrane transporter activity
EHC64_24265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC64_24270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC64_24280	COG3707	response regulator
EHC64_24300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHC64_24300	COG1648	precorrin-2 dehydrogenase activity
EHC64_24305	COG0243	molybdopterin cofactor binding
EHC64_24310	COG0456	acetyltransferase
EHC64_24315	COG0814	amino acid
EHC64_24325	COG0745	RESPONSE REGULATOR receiver
EHC64_24325	COG3706	GGDEF domain
EHC64_24345	COG1785	Belongs to the alkaline phosphatase family
EHC64_24360	COG0745	RESPONSE REGULATOR receiver
EHC64_24380	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EHC64_24395	COG1609	Transcriptional regulator
EHC64_24400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC64_24405	COG1879	ABC-type sugar transport system periplasmic component
EHC64_24410	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC64_24415	COG1129	ABC transporter
EHC64_24420	COG1869	D-ribose catabolic process
EHC64_24425	COG5001	Diguanylate cyclase
EHC64_24430	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC64_24490	COG2205	protein histidine kinase activity
EHC64_24490	COG0784	Response regulator, receiver
EHC64_24510	COG5001	Diguanylate cyclase
EHC64_24510	COG3300	MHYT domain
EHC64_24520	COG0330	HflC and HflK could
EHC64_24535	COG4175	Glycine betaine
EHC64_24535	COG0517	IMP dehydrogenase activity
EHC64_24540	COG4176	ABC-type proline glycine betaine transport system permease component
EHC64_24555	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_24560	COG1309	transcriptional regulator
EHC64_24565	COG3706	GGDEF domain
EHC64_24590	COG1024	Enoyl-CoA hydratase
EHC64_24595	COG1960	acyl-CoA dehydrogenase activity
EHC64_24605	COG0183	Belongs to the thiolase family
EHC64_24615	COG1960	acyl-CoA dehydrogenase activity
EHC64_24620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHC64_24640	COG3850	Histidine kinase
EHC64_24640	COG2205	protein histidine kinase activity
EHC64_24640	COG4999	Histidine kinase
EHC64_24640	COG3437	response regulator, receiver
EHC64_24655	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC64_24655	COG3264	Mechanosensitive ion channel
EHC64_24665	COG0110	maltose O-acetyltransferase activity
EHC64_24670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC64_24675	COG1271	oxidase subunit
EHC64_24680	COG1294	oxidase, subunit
EHC64_24690	COG0384	phenazine biosynthesis protein PhzF
EHC64_24695	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHC64_24700	COG0789	Transcriptional regulator
EHC64_24710	COG3474	cytochrome
EHC64_24720	COG0500	methyltransferase
EHC64_24780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC64_24905	COG2356	endonuclease I
EHC64_24995	COG1683	Conserved Protein
EHC64_25015	COG2026	Addiction module toxin, RelE StbE family
EHC64_25020	COG4115	mRNA cleavage
EHC64_25025	COG2161	toxin-antitoxin pair type II binding
EHC64_25045	COG0494	nUDIX hydrolase
EHC64_25075	COG1012	belongs to the aldehyde dehydrogenase family
EHC64_25090	COG2199	diguanylate cyclase activity
EHC64_25090	COG2200	EAL domain
EHC64_25090	COG2202	Pas domain
EHC64_25115	COG0840	transmembrane signaling receptor activity
EHC64_25130	COG0840	transmembrane signaling receptor activity
EHC64_25185	COG0464	growth
EHC64_25190	COG4974	Belongs to the 'phage' integrase family
EHC64_25195	COG0516	GMP reductase activity
EHC64_25200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EHC64_25200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHC64_25215	COG4989	oxidoreductase activity
EHC64_25230	COG0038	chloride channel
EHC64_25240	COG1914	H( )-stimulated, divalent metal cation uptake system
EHC64_25245	COG0302	gtp cyclohydrolase
EHC64_25255	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC64_25275	COG2897	thiosulfate sulfurtransferase activity
EHC64_25305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC64_25310	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC64_25315	COG0840	transmembrane signaling receptor activity
EHC64_25325	COG2814	Major facilitator Superfamily
EHC64_25330	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC64_25345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC64_25355	COG0840	transmembrane signaling receptor activity
EHC64_25375	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC64_25390	COG2197	response regulator
EHC64_25395	COG3850	Histidine kinase
EHC64_25400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHC64_25410	COG0243	molybdopterin cofactor binding
EHC64_25420	COG3005	denitrification pathway
EHC64_25440	COG0183	Belongs to the thiolase family
EHC64_25460	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC64_25465	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC64_25495	COG1522	sequence-specific DNA binding
EHC64_25515	COG1566	PFAM secretion protein HlyD family protein
EHC64_25525	COG0784	Response regulator, receiver
EHC64_25525	COG2205	protein histidine kinase activity
EHC64_25530	COG1879	ABC-type sugar transport system periplasmic component
EHC64_25535	COG2827	Endonuclease containing a URI domain
EHC64_25540	COG3132	Protein of unknown function, DUF480
EHC64_25555	COG2926	Belongs to the UPF0265 family
EHC64_25560	COG0534	Mate efflux family protein
EHC64_25565	COG0673	inositol 2-dehydrogenase activity
EHC64_25570	COG0784	Response regulator, receiver
EHC64_25570	COG5002	protein histidine kinase activity
EHC64_25570	COG2205	protein histidine kinase activity
EHC64_25595	COG1522	sequence-specific DNA binding
EHC64_25605	COG0531	amino acid
EHC64_25620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC64_25625	COG2239	Acts as a magnesium transporter
EHC64_25630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EHC64_25635	COG0402	S-adenosylhomocysteine deaminase activity
EHC64_25645	COG1418	mRNA catabolic process
EHC64_25660	COG2814	Major facilitator Superfamily
EHC64_25670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC64_25690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC64_25710	COG4221	oxidoreductase activity
EHC64_25715	COG0745	RESPONSE REGULATOR receiver
EHC64_25720	COG2205	protein histidine kinase activity
EHC64_25730	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC64_25735	COG2194	sulfuric ester hydrolase activity
EHC64_25740	COG0673	inositol 2-dehydrogenase activity
EHC64_25750	COG2814	Major facilitator Superfamily
EHC64_25765	COG1846	Transcriptional regulator
EHC64_25775	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC64_25780	COG1741	Belongs to the pirin family
EHC64_25785	COG1278	Cold shock
EHC64_25805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC64_25825	COG1686	Belongs to the peptidase S11 family
EHC64_25840	COG0625	glutathione transferase activity
EHC64_25850	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EHC64_25855	COG0494	nUDIX hydrolase
EHC64_25860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHC64_25880	COG1028	Short-chain dehydrogenase reductase Sdr
EHC64_25900	COG3746	phosphate-selective porin O and P
EHC64_25920	COG3833	ABC-type maltose transport systems, permease component
EHC64_25925	COG1175	transmembrane transport
EHC64_25935	COG3842	ATPase activity
EHC64_26000	COG1309	transcriptional regulator
EHC64_26005	COG2130	NADP-dependent
EHC64_26015	COG0753	catalase activity
EHC64_26020	COG2084	Dehydrogenase
EHC64_26025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_26030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_26040	COG2207	Transcriptional regulator
EHC64_26045	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC64_26045	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_26045	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC64_26060	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC64_26065	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EHC64_26075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC64_26080	COG0569	domain protein
EHC64_26090	COG5002	protein histidine kinase activity
EHC64_26095	COG1132	(ABC) transporter
EHC64_26100	COG4774	siderophore transport
EHC64_26105	COG1120	ATPase activity
EHC64_26110	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC64_26125	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EHC64_26125	COG2885	chlorophyll binding
EHC64_26160	COG2197	response regulator
EHC64_26170	COG0840	transmembrane signaling receptor activity
EHC64_26180	COG0714	Associated with various cellular activities
EHC64_26245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC64_26270	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EHC64_26270	COG2885	chlorophyll binding
EHC64_26280	COG2948	multi-organism process
EHC64_26295	COG3701	Conjugal transfer protein
EHC64_26315	COG3451	type IV secretory pathway VirB4
EHC64_26380	COG1192	Involved in chromosome partitioning
EHC64_26420	COG4932	domain protein
EHC64_26420	COG5492	domain, Protein
EHC64_26455	COG2885	chlorophyll binding
EHC64_26510	COG2337	Toxic component of a toxin-antitoxin (TA) module
EHC64_26520	COG4974	Belongs to the 'phage' integrase family
EHC64_26545	COG4932	domain protein
EHC64_26545	COG5492	domain, Protein
EHC64_26565	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EHC64_26580	COG0739	heme binding
EHC64_26735	COG4962	Type ii secretion system protein e
EHC64_26795	COG2801	Transposase and inactivated derivatives
EHC64_26860	COG1560	Kdo2-lipid A biosynthetic process
EHC64_26865	COG0251	oxidation-reduction process
EHC64_26875	COG2957	Belongs to the agmatine deiminase family
EHC64_26880	COG0531	amino acid
EHC64_26885	COG0549	Belongs to the carbamate kinase family
EHC64_27000	COG1192	Involved in chromosome partitioning
EHC64_27015	COG3157	Type VI secretion system effector, Hcp
EHC64_27315	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC64_27350	COG3504	Conjugal transfer protein
EHC64_27365	COG4962	Type ii secretion system protein e
EHC64_27375	COG3451	type IV secretory pathway VirB4
EHC64_27380	COG5268	conjugation
EHC64_27405	COG1192	Involved in chromosome partitioning
EHC64_27430	COG0419	ATPase involved in DNA repair