locus-tag	class	description
EHC68_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EHC68_00010	COG0592	DNA-directed DNA polymerase activity
EHC68_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EHC68_00020	COG0187	DNA topoisomerase II activity
EHC68_00040	COG0071	Belongs to the small heat shock protein (HSP20) family
EHC68_00045	COG3977	Valine--pyruvate aminotransferase
EHC68_00050	COG0366	Alpha amylase catalytic
EHC68_00055	COG0751	glycine-tRNA ligase activity
EHC68_00060	COG0752	glycyl-tRNA synthetase alpha subunit
EHC68_00065	COG2119	membrane
EHC68_00075	COG0425	Belongs to the sulfur carrier protein TusA family
EHC68_00090	COG0604	alcohol dehydrogenase
EHC68_00095	COG0183	Belongs to the thiolase family
EHC68_00100	COG1024	Enoyl-CoA hydratase
EHC68_00100	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC68_00105	COG1739	Uncharacterized protein family UPF0029
EHC68_00110	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC68_00170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EHC68_00175	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EHC68_00185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC68_00190	COG2104	thiamine diphosphate biosynthetic process
EHC68_00195	COG2022	thiamine diphosphate biosynthetic process
EHC68_00205	COG0006	proline dipeptidase activity
EHC68_00205	COG0006	proline dipeptidase activity
EHC68_00235	COG3220	belongs to the UPF0276 family
EHC68_00245	COG0210	DNA helicase
EHC68_00255	COG0405	Gamma-glutamyltransferase
EHC68_00260	COG1280	lysine exporter protein (LysE YggA)
EHC68_00270	COG2962	Rard protein
EHC68_00275	COG0514	ATP-dependent DNA helicase (RecQ)
EHC68_00290	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EHC68_00295	COG0248	Ppx GppA phosphatase
EHC68_00300	COG0513	Belongs to the DEAD box helicase family
EHC68_00305	COG3118	belongs to the thioredoxin family
EHC68_00310	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EHC68_00325	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EHC68_00330	COG0633	Ferredoxin
EHC68_00385	COG3071	HemY protein
EHC68_00390	COG2959	enzyme of heme biosynthesis
EHC68_00395	COG1587	Uroporphyrinogen-III synthase
EHC68_00400	COG0181	hydroxymethylbilane synthase activity
EHC68_00405	COG3072	Adenylate cyclase
EHC68_00410	COG1965	Belongs to the frataxin family
EHC68_00420	COG0019	diaminopimelate decarboxylase activity
EHC68_00425	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EHC68_00435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EHC68_00445	COG3287	FIST C domain
EHC68_00445	COG2200	EAL domain
EHC68_00445	COG2199	diguanylate cyclase activity
EHC68_00465	COG0561	phosphatase activity
EHC68_00475	COG2267	carboxylic ester hydrolase activity
EHC68_00480	COG1280	lysine exporter protein (LysE YggA)
EHC68_00485	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC68_00490	COG0640	Transcriptional regulator
EHC68_00495	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC68_00550	COG2095	MarC family integral membrane protein
EHC68_00560	COG0742	ribosomal rna small subunit methyltransferase
EHC68_00565	COG0552	protein localization to endoplasmic reticulum
EHC68_00570	COG2884	Cell division ATP-binding protein ftsE
EHC68_00575	COG2177	Part of the ABC transporter FtsEX involved in
EHC68_00590	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC68_00595	COG0705	Rhomboid family
EHC68_00600	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC68_00605	COG3161	chorismate lyase activity
EHC68_00610	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EHC68_00615	COG2937	Belongs to the GPAT DAPAT family
EHC68_00625	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHC68_00630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EHC68_00635	COG0534	Mate efflux family protein
EHC68_00640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC68_00660	COG0789	Transcriptional regulator
EHC68_00735	COG2003	Belongs to the UPF0758 family
EHC68_00745	COG0328	RNA-DNA hybrid ribonuclease activity
EHC68_00750	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHC68_00770	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHC68_00775	COG4206	TonB-dependent receptor
EHC68_00785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EHC68_00850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC68_00860	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EHC68_00895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC68_00905	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC68_00910	COG0250	Participates in transcription elongation, termination and antitermination
EHC68_00915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EHC68_00920	COG0081	regulation of translation
EHC68_00925	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EHC68_00930	COG0222	ribosome binding
EHC68_00935	COG0085	RNA polymerase activity
EHC68_00940	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EHC68_00945	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
EHC68_00950	COG2816	NAD+ diphosphatase activity
EHC68_00965	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EHC68_00970	COG1573	uracil-dna glycosylase
EHC68_00975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC68_00980	COG3068	Protein conserved in bacteria
EHC68_00985	COG1253	flavin adenine dinucleotide binding
EHC68_01000	COG0151	Belongs to the GarS family
EHC68_01010	COG0138	bifunctional purine biosynthesis protein purh
EHC68_01020	COG0789	Transcriptional regulator
EHC68_01025	COG3710	Transcriptional regulator
EHC68_01035	COG0531	amino acid
EHC68_01040	COG1982	Orn Lys Arg decarboxylase major
EHC68_01100	COG3706	GGDEF domain
EHC68_01105	COG0488	(ABC) transporter
EHC68_01110	COG2814	Major facilitator Superfamily
EHC68_01115	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EHC68_01120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC68_01125	COG2264	protein methyltransferase activity
EHC68_01135	COG0439	Biotin carboxylase
EHC68_01140	COG0511	ligase activity, forming carbon-carbon bonds
EHC68_01145	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EHC68_01150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC68_01165	COG2814	Major facilitator Superfamily
EHC68_01170	COG2205	protein histidine kinase activity
EHC68_01170	COG0784	Response regulator, receiver
EHC68_01195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC68_01205	COG3263	regulation of cellular component size
EHC68_01215	COG4232	protein-disulfide reductase activity
EHC68_01220	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC68_01225	COG1027	Aspartate ammonia-lyase
EHC68_01230	COG3030	protein affecting phage T7 exclusion by the F plasmid
EHC68_01235	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EHC68_01245	COG2205	protein histidine kinase activity
EHC68_01250	COG0745	RESPONSE REGULATOR receiver
EHC68_01260	COG3678	ATP-independent chaperone mediated protein folding
EHC68_01270	COG0205	6-phosphofructokinase activity
EHC68_01275	COG0534	Mate efflux family protein
EHC68_01280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC68_01285	COG0459	protein refolding
EHC68_01300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC68_01310	COG1509	lysine 2,3-aminomutase activity
EHC68_01315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC68_01325	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC68_01330	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EHC68_01335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC68_01340	COG1053	succinate dehydrogenase
EHC68_01350	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EHC68_01370	COG4942	peptidase
EHC68_01375	COG1045	serine acetyltransferase
EHC68_01380	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EHC68_01385	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
EHC68_01390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC68_01395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EHC68_01410	COG0471	metal ion transport
EHC68_01415	COG0688	phosphatidylethanolamine metabolic process
EHC68_01420	COG1162	GTPase activity
EHC68_01425	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EHC68_01495	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EHC68_01500	COG0802	atpase or kinase
EHC68_01510	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EHC68_01515	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EHC68_01525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EHC68_01530	COG0330	HflC and HflK could
EHC68_01535	COG0330	HflC and HflK could
EHC68_01540	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EHC68_01545	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EHC68_01555	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
EHC68_01560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC68_01560	COG1017	nitric oxide dioxygenase activity
EHC68_01565	COG1959	2 iron, 2 sulfur cluster binding
EHC68_01570	COG0557	exoribonuclease II activity
EHC68_01575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC68_01580	COG0546	phosphoglycolate phosphatase activity
EHC68_01585	COG0180	Tryptophanyl-tRNA synthetase
EHC68_01620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EHC68_01630	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_01640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC68_01645	COG3954	Phosphoribulokinase
EHC68_01650	COG3089	Belongs to the UPF0270 family
EHC68_01655	COG0429	hydrolase of the alpha beta-hydrolase fold
EHC68_01665	COG0488	(ABC) transporter
EHC68_01675	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC68_01690	COG1047	Peptidyl-prolyl cis-trans
EHC68_01700	COG1446	asparaginase
EHC68_01705	COG2900	Belongs to the SlyX family
EHC68_01715	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC68_01720	COG2964	Protein conserved in bacteria
EHC68_01725	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EHC68_01730	COG2923	Belongs to the DsrF TusC family
EHC68_01735	COG2168	tRNA wobble position uridine thiolation
EHC68_01745	COG0049	tRNA binding
EHC68_01750	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC68_01755	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EHC68_01760	COG2906	2 iron, 2 sulfur cluster binding
EHC68_01770	COG0281	malic enzyme
EHC68_01780	COG0626	cystathionine gamma-synthase activity
EHC68_01785	COG0460	homoserine dehydrogenase
EHC68_01785	COG0527	aspartate kinase activity
EHC68_01790	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EHC68_01800	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EHC68_01805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC68_01810	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EHC68_01815	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC68_01820	COG0137	argininosuccinate synthase activity
EHC68_01825	COG0165	Argininosuccinate lyase
EHC68_01825	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC68_01840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC68_01840	COG0678	peroxiredoxin activity
EHC68_01850	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EHC68_01880	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EHC68_01885	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EHC68_01895	COG0338	D12 class N6 adenine-specific DNA methyltransferase
EHC68_01900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EHC68_01905	COG0360	Binds together with S18 to 16S ribosomal RNA
EHC68_01910	COG2965	DNA replication, synthesis of RNA primer
EHC68_01920	COG0359	binds to the 23S rRNA
EHC68_01930	COG0305	Participates in initiation and elongation during chromosome replication
EHC68_01935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC68_01945	COG0432	Pfam Uncharacterised protein family UPF0047
EHC68_01950	COG0166	Belongs to the GPI family
EHC68_01960	COG0735	belongs to the Fur family
EHC68_01970	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC68_01995	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EHC68_02000	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC68_02005	COG0175	sulfate reduction
EHC68_02070	COG3335	DDE superfamily endonuclease
EHC68_02085	COG1410	methionine synthase
EHC68_02085	COG0646	methionine synthase
EHC68_02090	COG0527	aspartate kinase activity
EHC68_02100	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EHC68_02110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EHC68_02125	COG0629	single-stranded DNA binding
EHC68_02130	COG2199	diguanylate cyclase activity
EHC68_02130	COG2200	EAL domain
EHC68_02155	COG3409	Peptidoglycan-binding domain 1 protein
EHC68_02155	COG3267	Type II secretory pathway component ExeA
EHC68_02165	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC68_02170	COG1459	type II secretion system
EHC68_02215	COG1077	Cell shape determining protein MreB Mrl
EHC68_02220	COG1792	Involved in formation and maintenance of cell shape
EHC68_02225	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EHC68_02230	COG0424	maF-like protein
EHC68_02235	COG1530	ribonuclease E activity
EHC68_02240	COG3164	Protein of unknown function
EHC68_02245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC68_02250	COG0312	modulator of DNA gyrase
EHC68_02255	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EHC68_02260	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EHC68_02275	COG0564	pseudouridine synthase activity
EHC68_02280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC68_02285	COG3028	Belongs to the UPF0307 family
EHC68_02290	COG0312	modulator of DNA gyrase
EHC68_02295	COG2239	Acts as a magnesium transporter
EHC68_02300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_02305	COG1660	Displays ATPase and GTPase activities
EHC68_02310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_02315	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC68_02325	COG1137	ATPase activity
EHC68_02330	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EHC68_02340	COG0517	IMP dehydrogenase activity
EHC68_02340	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EHC68_02350	COG1127	ABC transporter
EHC68_02355	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EHC68_02360	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC68_02365	COG2854	intermembrane phospholipid transfer
EHC68_02375	COG5007	Belongs to the BolA IbaG family
EHC68_02380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EHC68_02385	COG0204	Acyl-transferase
EHC68_02390	COG0251	oxidation-reduction process
EHC68_02395	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
EHC68_02400	COG0540	Belongs to the ATCase OTCase family
EHC68_02410	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EHC68_02415	COG2235	arginine
EHC68_02445	COG0525	valine-tRNA ligase activity
EHC68_02450	COG2927	DNA polymerase III (CHI subunit)
EHC68_02455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC68_02460	COG0795	lipopolysaccharide-transporting ATPase activity
EHC68_02465	COG0795	lipopolysaccharide-transporting ATPase activity
EHC68_02475	COG4325	translation initiation factor activity
EHC68_02480	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_02510	COG0726	polysaccharide deacetylase
EHC68_02515	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC68_02520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EHC68_02525	COG1447	Phosphotransferase system cellobiose-specific component IIA
EHC68_02530	COG1486	melibiose metabolic process
EHC68_02535	COG3394	polysaccharide catabolic process
EHC68_02545	COG3437	response regulator, receiver
EHC68_02595	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_02625	COG0840	transmembrane signaling receptor activity
EHC68_02665	COG0741	lytic transglycosylase activity
EHC68_02670	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EHC68_02680	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EHC68_02690	COG2066	Belongs to the glutaminase family
EHC68_02695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC68_02700	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EHC68_02710	COG1872	DUF167
EHC68_02715	COG0762	integral membrane protein
EHC68_02720	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EHC68_02725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EHC68_02740	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EHC68_02745	COG1678	Uncharacterized ACR, COG1678
EHC68_02750	COG0189	ligase activity
EHC68_02755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EHC68_02760	COG2356	endonuclease I
EHC68_02765	COG3091	SprT-like family
EHC68_02775	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EHC68_02785	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC68_02790	COG0583	DNA-binding transcription factor activity
EHC68_02795	COG4771	TonB-dependent receptor
EHC68_02800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC68_02805	COG0126	phosphoglycerate kinase activity
EHC68_02810	COG0191	fructose-bisphosphate aldolase activity
EHC68_02815	COG0668	transmembrane transport
EHC68_02820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EHC68_02830	COG0583	DNA-binding transcription factor activity
EHC68_02840	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC68_02845	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EHC68_02850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EHC68_02860	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
EHC68_02870	COG3079	Belongs to the UPF0149 family
EHC68_02875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC68_02880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC68_02895	COG0354	folic acid binding
EHC68_02900	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EHC68_02910	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EHC68_02920	COG1595	DNA-templated transcription, initiation
EHC68_02925	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EHC68_02935	COG3086	response to oxidative stress
EHC68_02940	COG0481	GTPase activity
EHC68_02945	COG0681	Belongs to the peptidase S26 family
EHC68_02950	COG0571	ribonuclease III activity
EHC68_02955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EHC68_02960	COG1381	Involved in DNA repair and RecF pathway recombination
EHC68_02965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EHC68_02970	COG0736	holo-[acyl-carrier-protein] synthase activity
EHC68_02980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EHC68_02990	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC68_02995	COG3956	TIGRFAM MazG family protein
EHC68_03000	COG0504	CTP synthase activity
EHC68_03005	COG0148	phosphopyruvate hydratase activity
EHC68_03010	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EHC68_03015	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EHC68_03020	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EHC68_03025	COG0585	pseudouridine synthase activity
EHC68_03030	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EHC68_03035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EHC68_03050	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EHC68_03055	COG1546	Belongs to the CinA family
EHC68_03060	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EHC68_03065	COG2137	regulation of response to DNA damage stimulus
EHC68_03070	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC68_03075	COG0527	aspartate kinase activity
EHC68_03135	COG3630	sodium ion export across plasma membrane
EHC68_03140	COG0511	ligase activity, forming carbon-carbon bonds
EHC68_03140	COG5016	pyruvate
EHC68_03145	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
EHC68_03150	COG1063	alcohol dehydrogenase
EHC68_03155	COG1238	metal cluster binding
EHC68_03160	COG0612	Peptidase, M16
EHC68_03165	COG2918	glutathione biosynthetic process
EHC68_03175	COG1854	S-ribosylhomocysteine lyase activity
EHC68_03180	COG4536	flavin adenine dinucleotide binding
EHC68_03185	COG4137	Cytochrome C assembly protein
EHC68_03190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EHC68_03195	COG0228	four-way junction DNA binding
EHC68_03200	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EHC68_03205	COG0336	Belongs to the RNA methyltransferase TrmD family
EHC68_03210	COG0335	large ribosomal subunit rRNA binding
EHC68_03215	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EHC68_03220	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EHC68_03225	COG0237	dephospho-CoA kinase activity
EHC68_03235	COG1459	type II secretion system
EHC68_03240	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC68_03250	COG0157	Belongs to the NadC ModD family
EHC68_03290	COG0288	reversible hydration of carbon dioxide
EHC68_03295	COG0659	secondary active sulfate transmembrane transporter activity
EHC68_03305	COG1131	(ABC) transporter
EHC68_03310	COG0842	Transport permease protein
EHC68_03320	COG1560	Kdo2-lipid A biosynthetic process
EHC68_03330	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EHC68_03335	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EHC68_03340	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHC68_03355	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC68_03365	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC68_03370	COG1489	DNA binding
EHC68_03375	COG1643	Atp-dependent helicase
EHC68_03380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC68_03385	COG1752	Esterase of the alpha-beta hydrolase superfamily
EHC68_03390	COG1049	propionate catabolic process, 2-methylcitrate cycle
EHC68_03395	COG3112	Uncharacterised protein family (UPF0231)
EHC68_03405	COG0004	ammonium transporteR
EHC68_03410	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC68_03420	COG3842	ATPase activity
EHC68_03425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC68_03440	COG2971	BadF BadG BcrA BcrD
EHC68_03450	COG4608	Belongs to the ABC transporter superfamily
EHC68_03455	COG0444	Belongs to the ABC transporter superfamily
EHC68_03460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC68_03470	COG0747	negative chemotaxis
EHC68_03475	COG2205	protein histidine kinase activity
EHC68_03475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_03475	COG2198	Histidine kinase
EHC68_03475	COG0784	Response regulator, receiver
EHC68_03485	COG2813	Specifically methylates the guanine in position
EHC68_03490	COG0628	permease
EHC68_03495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EHC68_03500	COG0316	Belongs to the HesB IscA family
EHC68_03510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC68_03515	COG0739	heme binding
EHC68_03520	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC68_03530	COG2027	D-alanyl-D-alanine carboxypeptidase
EHC68_03535	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC68_03540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC68_03545	COG1534	Rna-binding protein
EHC68_03550	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EHC68_03555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EHC68_03560	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EHC68_03565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC68_03575	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EHC68_03590	COG0779	Required for maturation of 30S ribosomal subunits
EHC68_03595	COG0195	Participates in both transcription termination and antitermination
EHC68_03600	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EHC68_03605	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EHC68_03610	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EHC68_03615	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EHC68_03620	COG1185	polyribonucleotide nucleotidyltransferase activity
EHC68_03635	COG0534	Mate efflux family protein
EHC68_03660	COG3153	acetyltransferase
EHC68_03680	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EHC68_03690	COG0084	hydrolase, TatD family'
EHC68_03695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC68_03700	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EHC68_03705	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
EHC68_03710	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
EHC68_03715	COG0813	purine-nucleoside phosphorylase activity
EHC68_03725	COG0560	Phosphoserine phosphatase
EHC68_03735	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EHC68_03740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC68_03745	COG0583	DNA-binding transcription factor activity
EHC68_03755	COG1022	Amp-dependent synthetase and ligase
EHC68_03760	COG2169	Transcriptional regulator
EHC68_03785	COG4964	Belongs to the GSP D family
EHC68_03845	COG0583	DNA-binding transcription factor activity
EHC68_03850	COG0531	amino acid
EHC68_03855	COG2731	YhcH YjgK YiaL family protein
EHC68_03860	COG3250	beta-galactosidase activity
EHC68_03865	COG1609	Transcriptional regulator
EHC68_03885	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
EHC68_03890	COG2017	converts alpha-aldose to the beta-anomer
EHC68_03905	COG2211	Major facilitator Superfamily
EHC68_03910	COG1609	Transcriptional regulator
EHC68_03915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC68_03930	COG0598	Magnesium transport protein CorA
EHC68_03935	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EHC68_03940	COG1349	DNA-binding transcription factor activity
EHC68_03945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EHC68_03950	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC68_03965	COG2271	Major facilitator Superfamily
EHC68_03970	COG0584	glycerophosphoryl diester phosphodiesterase
EHC68_03975	COG2171	N-acyltransferase activity
EHC68_03980	COG3141	response to X-ray
EHC68_04000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EHC68_04010	COG1074	ATP-dependent DNA helicase activity
EHC68_04015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EHC68_04025	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EHC68_04025	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EHC68_04040	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EHC68_04045	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EHC68_04050	COG2166	iron-sulfur cluster assembly
EHC68_04060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EHC68_04065	COG0693	protein deglycase activity
EHC68_04070	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EHC68_04100	COG1595	DNA-templated transcription, initiation
EHC68_04120	COG3056	Lipoprotein
EHC68_04125	COG2813	Specifically methylates the guanine in position
EHC68_04130	COG0271	Belongs to the BolA IbaG family
EHC68_04135	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC68_04140	COG1805	sodium ion transport
EHC68_04145	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC68_04150	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC68_04155	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EHC68_04160	COG2871	sodium ion transport
EHC68_04180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHC68_04185	COG0514	ATP-dependent DNA helicase (RecQ)
EHC68_04190	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC68_04205	COG0733	neurotransmitter:sodium symporter activity
EHC68_04225	COG0442	prolyl-tRNA aminoacylation
EHC68_04230	COG1720	tRNA m6t6A37 methyltransferase activity
EHC68_04235	COG0254	rRNA binding
EHC68_04250	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC68_04255	COG1671	Belongs to the UPF0178 family
EHC68_04280	COG3098	single-species biofilm formation
EHC68_04285	COG0564	pseudouridine synthase activity
EHC68_04295	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EHC68_04300	COG0024	Methionine aminopeptidase
EHC68_04305	COG0052	Belongs to the universal ribosomal protein uS2 family
EHC68_04310	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EHC68_04315	COG0528	UMP kinase activity
EHC68_04320	COG0233	cytoplasmic translational termination
EHC68_04325	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EHC68_04330	COG0575	Belongs to the CDS family
EHC68_04335	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EHC68_04340	COG0750	zinc metalloprotease
EHC68_04350	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EHC68_04355	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC68_04360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC68_04365	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC68_04370	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC68_04375	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EHC68_04380	COG0587	DNA-directed DNA polymerase activity
EHC68_04385	COG0825	malonyl-CoA metabolic process
EHC68_04390	COG0037	tRNA processing
EHC68_04400	COG0347	Belongs to the P(II) protein family
EHC68_04405	COG3021	interspecies interaction between organisms
EHC68_04415	COG1388	LysM domain
EHC68_04415	COG0741	lytic transglycosylase activity
EHC68_04420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC68_04425	COG2226	methyltransferase
EHC68_04430	COG0328	RNA-DNA hybrid ribonuclease activity
EHC68_04435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC68_04450	COG1960	acyl-CoA dehydrogenase activity
EHC68_04455	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC68_04460	COG0121	glutamine amidotransferase
EHC68_04465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EHC68_04470	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EHC68_04475	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EHC68_04480	COG2233	PERMEase
EHC68_04500	COG1393	Belongs to the ArsC family
EHC68_04505	COG4783	chaperone-mediated protein folding
EHC68_04520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EHC68_04525	COG2716	regulation of RNA biosynthetic process
EHC68_04530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC68_04550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC68_04555	COG1393	Belongs to the ArsC family
EHC68_04585	COG2837	iron assimilation
EHC68_04590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_04600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_04605	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_04610	COG1334	flagellar protein FlaG
EHC68_04615	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
EHC68_04625	COG1516	flagellar protein fliS
EHC68_04635	COG4191	Histidine kinase
EHC68_04640	COG2204	response regulator
EHC68_04645	COG1677	Flagellar hook-basal body complex protein FliE
EHC68_04655	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC68_04705	COG1987	bacterial-type flagellum assembly
EHC68_04710	COG1684	flagellar biosynthetic protein fliR
EHC68_04730	COG0455	bacterial-type flagellum organization
EHC68_04745	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EHC68_04750	COG2198	Histidine kinase
EHC68_04750	COG0643	Histidine kinase
EHC68_04755	COG2201	protein-glutamate methylesterase activity
EHC68_04760	COG1192	Involved in chromosome partitioning
EHC68_04770	COG0835	chemotaxis
EHC68_04780	COG4133	protoheme IX ABC transporter activity
EHC68_04785	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC68_04790	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC68_04795	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EHC68_04800	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
EHC68_04805	COG1138	Cytochrome C-type biogenesis protein
EHC68_04810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EHC68_04825	COG2853	Lipoprotein
EHC68_04835	COG2067	long-chain fatty acid transport protein
EHC68_04855	COG0183	Belongs to the thiolase family
EHC68_04860	COG1250	3-hydroxyacyl-CoA dehydrogenase
EHC68_04860	COG1024	Enoyl-CoA hydratase
EHC68_04875	COG2062	phosphohistidine phosphatase, SixA
EHC68_04880	COG2840	Smr protein MutS2
EHC68_04885	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC68_04890	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EHC68_04895	COG2860	membrane
EHC68_04905	COG3101	peptidyl-lysine hydroxylation
EHC68_04920	COG0431	NADPH-dependent FMN reductase
EHC68_04925	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EHC68_04925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC68_04930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC68_04940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EHC68_04945	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC68_04955	COG0101	tRNA pseudouridine synthase activity
EHC68_04960	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC68_04965	COG0285	dihydrofolate synthase activity
EHC68_04975	COG1286	toxin biosynthetic process
EHC68_04980	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EHC68_04985	COG0583	DNA-binding transcription factor activity
EHC68_04990	COG0745	RESPONSE REGULATOR receiver
EHC68_05000	COG2832	Protein of unknown function (DUF454)
EHC68_05005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EHC68_05015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EHC68_05020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EHC68_05025	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EHC68_05030	COG0814	amino acid
EHC68_05035	COG0251	oxidation-reduction process
EHC68_05040	COG3681	Belongs to the UPF0597 family
EHC68_05055	COG2261	transglycosylase associated protein
EHC68_05060	COG2983	Belongs to the UPF0260 family
EHC68_05065	COG0668	transmembrane transport
EHC68_05070	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EHC68_05075	COG0346	lactoylglutathione lyase activity
EHC68_05085	COG1785	Belongs to the alkaline phosphatase family
EHC68_05105	COG2226	methyltransferase
EHC68_05120	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EHC68_05125	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC68_05135	COG3139	Protein of unknown function (DUF1315)
EHC68_05140	COG0252	asparaginase activity
EHC68_05145	COG0616	signal peptide processing
EHC68_05150	COG1902	pentaerythritol trinitrate reductase activity
EHC68_05150	COG0446	pyridine nucleotide-disulphide oxidoreductase
EHC68_05160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC68_05180	COG0123	including yeast histone deacetylase and acetoin utilization protein
EHC68_05230	COG3083	sulfuric ester hydrolase activity
EHC68_05235	COG3082	Protein of unknown function (DUF1414)
EHC68_05240	COG3081	Nucleoid-associated protein
EHC68_05255	COG1757	Na H antiporter
EHC68_05260	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EHC68_05265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC68_05270	COG2095	MarC family integral membrane protein
EHC68_05275	COG1454	alcohol dehydrogenase
EHC68_05275	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_05295	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EHC68_05305	COG2056	Na+-H+ antiporter family
EHC68_05310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EHC68_05325	COG2885	chlorophyll binding
EHC68_05335	COG0346	lactoylglutathione lyase activity
EHC68_05340	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EHC68_05345	COG4660	Part of a membrane complex involved in electron transport
EHC68_05350	COG4659	FMN binding
EHC68_05355	COG4658	electron transport chain
EHC68_05360	COG4656	Part of a membrane complex involved in electron transport
EHC68_05365	COG2878	Part of a membrane complex involved in electron transport
EHC68_05370	COG4657	Part of a membrane complex involved in electron transport
EHC68_05385	COG0556	nucleotide-excision repair
EHC68_05390	COG2204	response regulator
EHC68_05395	COG2198	Histidine kinase
EHC68_05400	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EHC68_05405	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EHC68_05410	COG0521	Mo-molybdopterin cofactor biosynthetic process
EHC68_05415	COG0315	cyclic pyranopterin monophosphate synthase activity
EHC68_05420	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EHC68_05425	COG0314	molybdopterin synthase activity
EHC68_05435	COG0601	transmembrane transport
EHC68_05440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC68_05445	COG0444	Belongs to the ABC transporter superfamily
EHC68_05455	COG0435	Glutathione S-transferase
EHC68_05465	COG3174	membrane
EHC68_05470	COG0280	phosphate acetyltransferase
EHC68_05470	COG0857	belongs to the CobB CobQ family
EHC68_05475	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC68_05480	COG3092	negative regulation of chromosome organization
EHC68_05490	COG4120	Belongs to the binding-protein-dependent transport system permease family
EHC68_05495	COG1122	ATPase activity
EHC68_05500	COG0366	Alpha amylase catalytic
EHC68_05505	COG3706	GGDEF domain
EHC68_05505	COG0745	RESPONSE REGULATOR receiver
EHC68_05510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EHC68_05515	COG3012	SEC-C Motif Domain Protein
EHC68_05515	COG3318	Belongs to the UPF0149 family
EHC68_05520	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EHC68_05525	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC68_05530	COG2186	Transcriptional regulator
EHC68_05540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC68_05540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC68_05550	COG0572	uridine kinase
EHC68_05560	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EHC68_05565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EHC68_05570	COG0659	secondary active sulfate transmembrane transporter activity
EHC68_05580	COG1530	ribonuclease E activity
EHC68_05595	COG0564	pseudouridine synthase activity
EHC68_05600	COG0424	maF-like protein
EHC68_05605	COG1399	metal-binding, possibly nucleic acid-binding protein
EHC68_05615	COG0416	fatty acid biosynthetic process
EHC68_05620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC68_05650	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EHC68_05655	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EHC68_05665	COG0084	hydrolase, TatD family'
EHC68_05670	COG1263	PTS System
EHC68_05670	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC68_05690	COG0733	neurotransmitter:sodium symporter activity
EHC68_05705	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC68_05710	COG0469	pyruvate kinase activity
EHC68_05715	COG1940	carbohydrate kinase activity
EHC68_05720	COG0835	chemotaxis
EHC68_05720	COG0784	Response regulator, receiver
EHC68_05725	COG0587	DNA-directed DNA polymerase activity
EHC68_05740	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_05745	COG0616	signal peptide processing
EHC68_05750	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EHC68_05755	COG0539	negative regulation of cytoplasmic translation
EHC68_05765	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EHC68_05770	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EHC68_05775	COG0284	orotidine-5'-phosphate decarboxylase activity
EHC68_05780	COG4166	transmembrane transport
EHC68_05805	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EHC68_05815	COG3008	intermembrane lipid transfer
EHC68_05815	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EHC68_05820	COG2995	paraquat-inducible protein a
EHC68_05825	COG3258	Cytochrome c
EHC68_05830	COG2863	cytochrome
EHC68_05870	COG4232	protein-disulfide reductase activity
EHC68_05875	COG3118	belongs to the thioredoxin family
EHC68_05895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_05905	COG1136	(ABC) transporter
EHC68_05905	COG0577	efflux transmembrane transporter activity
EHC68_05915	COG1136	(ABC) transporter
EHC68_05915	COG0577	efflux transmembrane transporter activity
EHC68_05920	COG1335	isochorismatase
EHC68_05935	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC68_05970	COG3850	Histidine kinase
EHC68_05970	COG5002	protein histidine kinase activity
EHC68_05975	COG0745	RESPONSE REGULATOR receiver
EHC68_05985	COG0840	transmembrane signaling receptor activity
EHC68_05990	COG1032	radical SAM domain protein
EHC68_05995	COG4251	negative regulation of phosphorylation
EHC68_05995	COG5001	Diguanylate cyclase
EHC68_05995	COG3706	GGDEF domain
EHC68_05995	COG2203	Gaf domain
EHC68_06010	COG0583	DNA-binding transcription factor activity
EHC68_06020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EHC68_06030	COG2350	Protein conserved in bacteria
EHC68_06035	COG1607	acyl-coa hydrolase
EHC68_06040	COG2917	probably involved in intracellular septation
EHC68_06060	COG1301	dicarboxylic acid transport
EHC68_06070	COG0318	PFAM AMP-dependent synthetase and ligase
EHC68_06075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC68_06080	COG0159	tryptophan synthase activity
EHC68_06085	COG0133	tryptophan synthase activity
EHC68_06090	COG0135	phosphoribosylanthranilate isomerase activity
EHC68_06090	COG0134	indole-3-glycerol-phosphate synthase activity
EHC68_06095	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EHC68_06100	COG0512	Glutamine amidotransferase of anthranilate synthase
EHC68_06105	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC68_06115	COG0613	PHP domain protein
EHC68_06120	COG0009	L-threonylcarbamoyladenylate synthase
EHC68_06130	COG1187	pseudouridine synthase activity
EHC68_06140	COG3099	Belongs to the UPF0263 family
EHC68_06145	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EHC68_06155	COG0417	DNA replication proofreading
EHC68_06160	COG2197	response regulator
EHC68_06165	COG0322	excinuclease ABC activity
EHC68_06205	COG0019	diaminopimelate decarboxylase activity
EHC68_06230	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC68_06235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EHC68_06240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC68_06260	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
EHC68_06270	COG0437	4 iron, 4 sulfur cluster binding
EHC68_06275	COG3301	Polysulphide reductase, NrfD
EHC68_06280	COG1138	Cytochrome C-type biogenesis protein
EHC68_06290	COG3088	subunit of a heme lyase
EHC68_06290	COG4235	cytochrome complex assembly
EHC68_06300	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC68_06325	COG2989	Protein conserved in bacteria
EHC68_06330	COG3108	Peptidase M15
EHC68_06335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EHC68_06350	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EHC68_06375	COG1846	Transcriptional regulator
EHC68_06380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC68_06385	COG0840	transmembrane signaling receptor activity
EHC68_06405	COG1448	Aminotransferase
EHC68_06430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC68_06440	COG0017	Asparaginyl-tRNA synthetase
EHC68_06450	COG0720	synthase
EHC68_06460	COG2200	EAL domain
EHC68_06465	COG1760	l-serine dehydratase
EHC68_06470	COG0814	amino acid
EHC68_06475	COG0494	nUDIX hydrolase
EHC68_06485	COG0784	Response regulator, receiver
EHC68_06485	COG2205	protein histidine kinase activity
EHC68_06490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EHC68_06510	COG3106	COG3106 Predicted ATPase
EHC68_06515	COG3768	UPF0283 membrane protein
EHC68_06525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC68_06675	COG0494	nUDIX hydrolase
EHC68_06745	COG1280	lysine exporter protein (LysE YggA)
EHC68_06955	COG0251	oxidation-reduction process
EHC68_07160	COG1335	isochorismatase
EHC68_07215	COG0494	nUDIX hydrolase
EHC68_07305	COG1280	lysine exporter protein (LysE YggA)
EHC68_07540	COG1683	Conserved Protein
EHC68_07600	COG0346	lactoylglutathione lyase activity
EHC68_07610	COG0546	phosphoglycolate phosphatase activity
EHC68_07900	COG1757	Na H antiporter
EHC68_07905	COG0174	glutamine synthetase
EHC68_07915	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EHC68_07920	COG1917	Cupin 2, conserved barrel domain protein
EHC68_07920	COG1396	sequence-specific DNA binding
EHC68_07925	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_07930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC68_07940	COG2957	Belongs to the agmatine deiminase family
EHC68_07945	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_07950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC68_07955	COG1227	inorganic diphosphatase activity
EHC68_07965	COG2200	EAL domain
EHC68_07965	COG2771	luxR family
EHC68_07980	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EHC68_07995	COG1846	Transcriptional regulator
EHC68_08000	COG2315	Protein conserved in bacteria
EHC68_08020	COG0110	maltose O-acetyltransferase activity
EHC68_08035	COG2205	protein histidine kinase activity
EHC68_08035	COG5002	protein histidine kinase activity
EHC68_08035	COG0784	Response regulator, receiver
EHC68_08050	COG3063	Type IV pilus biogenesis stability protein PilW
EHC68_08055	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
EHC68_08070	COG0531	amino acid
EHC68_08080	COG1560	Kdo2-lipid A biosynthetic process
EHC68_08090	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EHC68_08125	COG3706	GGDEF domain
EHC68_08180	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EHC68_08185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EHC68_08225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EHC68_08310	COG3550	peptidyl-serine autophosphorylation
EHC68_08315	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EHC68_08320	COG1280	lysine exporter protein (LysE YggA)
EHC68_08330	COG1115	amino acid carrier protein
EHC68_08355	COG1368	sulfuric ester hydrolase activity
EHC68_08360	COG0642	Histidine kinase
EHC68_08365	COG0745	RESPONSE REGULATOR receiver
EHC68_08375	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_08395	COG2113	Glycine betaine
EHC68_08400	COG4176	ABC-type proline glycine betaine transport system permease component
EHC68_08420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC68_08425	COG0456	acetyltransferase
EHC68_08430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EHC68_08435	COG0662	Cupin 2, conserved barrel domain protein
EHC68_08440	COG0527	aspartate kinase activity
EHC68_08460	COG1858	cytochrome C peroxidase
EHC68_08475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_08490	COG3290	protein histidine kinase activity
EHC68_08495	COG4565	transcriptional regulatory protein
EHC68_08500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EHC68_08505	COG0363	glucosamine-6-phosphate deaminase activity
EHC68_08510	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EHC68_08535	COG3284	Transcriptional regulator
EHC68_08540	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_08610	COG4669	(LipO)protein
EHC68_08630	COG3177	Filamentation induced by cAMP protein fic
EHC68_08670	COG1073	alpha beta
EHC68_08675	COG1073	alpha beta
EHC68_08685	COG4792	protein secretion
EHC68_08690	COG4791	protein targeting
EHC68_08695	COG4794	Type iii secretion
EHC68_08700	COG4790	Type iii secretion
EHC68_08705	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC68_08770	COG0457	Tetratricopeptide repeat
EHC68_08790	COG0730	response to heat
EHC68_08820	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
EHC68_08825	COG0372	Belongs to the citrate synthase family
EHC68_08835	COG2828	Protein conserved in bacteria
EHC68_08860	COG0561	phosphatase activity
EHC68_08865	COG0602	queuosine metabolic process
EHC68_08870	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EHC68_08875	COG3706	GGDEF domain
EHC68_08915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC68_08920	COG0840	transmembrane signaling receptor activity
EHC68_08925	COG1254	Belongs to the acylphosphatase family
EHC68_08930	COG2920	part of a sulfur-relay system
EHC68_08940	COG0670	Belongs to the BI1 family
EHC68_08945	COG1126	abc transporter atp-binding protein
EHC68_08950	COG0765	amino acid transport
EHC68_08960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_08980	COG1666	GTP binding
EHC68_08985	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC68_09005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC68_09005	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
EHC68_09015	COG3008	intermembrane lipid transfer
EHC68_09020	COG2995	paraquat-inducible protein a
EHC68_09025	COG1132	(ABC) transporter
EHC68_09030	COG1956	GAF domain-containing protein
EHC68_09035	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EHC68_09050	COG0308	aminopeptidase N
EHC68_09060	COG2902	Dehydrogenase
EHC68_09065	COG0167	dihydroorotate dehydrogenase activity
EHC68_09080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EHC68_09080	COG0116	Belongs to the methyltransferase superfamily
EHC68_09105	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC68_09110	COG1067	ATP-dependent peptidase activity
EHC68_09115	COG3120	sequence-specific DNA binding
EHC68_09165	COG3278	Belongs to the heme-copper respiratory oxidase family
EHC68_09180	COG2010	Cytochrome c
EHC68_09190	COG2217	Heavy metal translocating P-type atpase
EHC68_09205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EHC68_09210	COG0589	response to stress
EHC68_09220	COG0037	tRNA processing
EHC68_09240	COG3842	ATPase activity
EHC68_09245	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC68_09250	COG1177	transmembrane transport
EHC68_09255	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC68_09260	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC68_09265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EHC68_09275	COG0004	ammonium transporteR
EHC68_09300	COG0437	4 iron, 4 sulfur cluster binding
EHC68_09305	COG3383	formate dehydrogenase (NAD+) activity
EHC68_09305	COG0243	molybdopterin cofactor binding
EHC68_09315	COG3381	protein complex oligomerization
EHC68_09340	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC68_09345	COG0488	(ABC) transporter
EHC68_09355	COG4191	Histidine kinase
EHC68_09360	COG2204	response regulator
EHC68_09380	COG3842	ATPase activity
EHC68_09385	COG0746	molybdenum cofactor guanylyltransferase activity
EHC68_09390	COG0303	'Molybdopterin
EHC68_09400	COG1940	carbohydrate kinase activity
EHC68_09445	COG0791	NLP P60 protein
EHC68_09455	COG3706	GGDEF domain
EHC68_09460	COG2201	protein-glutamate methylesterase activity
EHC68_09475	COG0307	riboflavin synthase, alpha
EHC68_09480	COG0534	Mate efflux family protein
EHC68_09490	COG1793	dna ligase
EHC68_09525	COG2204	response regulator
EHC68_09535	COG0438	transferase activity, transferring glycosyl groups
EHC68_09570	COG0438	transferase activity, transferring glycosyl groups
EHC68_09575	COG1215	transferase activity, transferring glycosyl groups
EHC68_09580	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC68_09590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC68_09610	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EHC68_09625	COG3302	dmso reductase anchor subunit
EHC68_09630	COG0437	4 iron, 4 sulfur cluster binding
EHC68_09635	COG0243	molybdopterin cofactor binding
EHC68_09675	COG0443	Heat shock 70 kDa protein
EHC68_09680	COG0443	Heat shock 70 kDa protein
EHC68_09710	COG1132	(ABC) transporter
EHC68_09715	COG1132	(ABC) transporter
EHC68_09740	COG0814	amino acid
EHC68_09755	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EHC68_09835	COG1522	sequence-specific DNA binding
EHC68_09870	COG0515	serine threonine protein kinase
EHC68_09895	COG3501	Rhs element vgr protein
EHC68_09935	COG0739	heme binding
EHC68_09945	COG0861	Integral membrane protein TerC family
EHC68_09955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC68_09960	COG1328	CTP reductase activity
EHC68_09965	COG1280	lysine exporter protein (LysE YggA)
EHC68_09975	COG5001	Diguanylate cyclase
EHC68_09975	COG3300	MHYT domain
EHC68_09985	COG4191	Histidine kinase
EHC68_09985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_09990	COG0471	metal ion transport
EHC68_10025	COG0583	DNA-binding transcription factor activity
EHC68_10030	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC68_10095	COG0758	DNA mediated transformation
EHC68_10225	COG1783	phage Terminase large subunit
EHC68_10390	COG0625	glutathione transferase activity
EHC68_10400	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
EHC68_10415	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC68_10425	COG0601	transmembrane transport
EHC68_10430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC68_10435	COG0444	Belongs to the ABC transporter superfamily
EHC68_10455	COG3291	Pkd domain containing protein
EHC68_10470	COG1177	transmembrane transport
EHC68_10475	COG1176	ABC-type spermidine putrescine transport system, permease component I
EHC68_10480	COG3842	ATPase activity
EHC68_10485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EHC68_10490	COG2423	ornithine cyclodeaminase activity
EHC68_10510	COG3938	Belongs to the proline racemase family
EHC68_10540	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
EHC68_10545	COG1451	nucleotide metabolic process
EHC68_10555	COG0583	DNA-binding transcription factor activity
EHC68_10575	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EHC68_10580	COG4139	cobalamin transport
EHC68_10585	COG2988	succinylglutamate desuccinylase activity
EHC68_10600	COG2062	phosphohistidine phosphatase, SixA
EHC68_10610	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EHC68_10615	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EHC68_10620	COG0702	epimerase
EHC68_10630	COG2925	Exonuclease
EHC68_10635	COG1380	Effector of murein hydrolase LrgA
EHC68_10640	COG1346	cytolysis
EHC68_10645	COG0295	cytidine deaminase activity
EHC68_10650	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EHC68_10655	COG0500	methyltransferase
EHC68_10665	COG0776	regulation of translation
EHC68_10680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EHC68_10680	COG0072	phenylalanine-tRNA ligase activity
EHC68_10685	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EHC68_10690	COG3706	GGDEF domain
EHC68_10720	COG0393	Putative heavy-metal-binding
EHC68_10730	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EHC68_10740	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EHC68_10755	COG2188	Transcriptional regulator
EHC68_10760	COG1228	amidohydrolase
EHC68_10765	COG0010	Belongs to the arginase family
EHC68_10770	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EHC68_10775	COG2986	histidine ammonia-lyase
EHC68_10790	COG0277	FAD linked oxidase domain protein
EHC68_10790	COG0247	lactate metabolic process
EHC68_10825	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EHC68_10840	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EHC68_10845	COG1643	Atp-dependent helicase
EHC68_10850	COG0281	malic enzyme
EHC68_10855	COG2949	membrane
EHC68_10860	COG0471	metal ion transport
EHC68_10865	COG3706	GGDEF domain
EHC68_10865	COG0745	RESPONSE REGULATOR receiver
EHC68_10885	COG0492	ferredoxin-NADP+ reductase activity
EHC68_10890	COG4988	ABC transporter
EHC68_10895	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EHC68_10900	COG3048	D-serine ammonia-lyase activity
EHC68_10905	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EHC68_10915	COG4191	Histidine kinase
EHC68_10915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_10930	COG3070	regulator of competence-specific genes
EHC68_10950	COG2431	L-lysine efflux transmembrane transporter activity
EHC68_10960	COG0076	glutamate decarboxylase activity
EHC68_10965	COG1737	Transcriptional regulator
EHC68_10980	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EHC68_10985	COG2985	domain, Protein
EHC68_10985	COG3273	potassium ion transport
EHC68_10990	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EHC68_11005	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC68_11020	COG4181	ATPase activity
EHC68_11025	COG0534	Mate efflux family protein
EHC68_11030	COG0702	epimerase
EHC68_11035	COG3005	denitrification pathway
EHC68_11065	COG2814	Major facilitator Superfamily
EHC68_11070	COG1187	pseudouridine synthase activity
EHC68_11075	COG1061	Type III restriction enzyme res subunit
EHC68_11085	COG0745	RESPONSE REGULATOR receiver
EHC68_11090	COG2205	protein histidine kinase activity
EHC68_11095	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EHC68_11135	COG3313	Fe-S protein
EHC68_11160	COG0493	'glutamate synthase
EHC68_11170	COG0398	Pfam SNARE associated Golgi protein
EHC68_11175	COG4134	Bacterial extracellular solute-binding protein
EHC68_11180	COG4135	transport system, permease component
EHC68_11185	COG4136	ATPase activity
EHC68_11190	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EHC68_11205	COG3604	Transcriptional regulator
EHC68_11210	COG1151	hydroxylamine reductase activity
EHC68_11215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC68_11225	COG0564	pseudouridine synthase activity
EHC68_11235	COG0733	neurotransmitter:sodium symporter activity
EHC68_11245	COG0626	cystathionine gamma-synthase activity
EHC68_11250	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
EHC68_11255	COG5380	lipid catabolic process
EHC68_11260	COG2818	Glycosylase
EHC68_11275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_11280	COG1983	PspC domain protein
EHC68_11290	COG1842	Phage shock protein A
EHC68_11295	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EHC68_11305	COG4168	peptide transport system, permease
EHC68_11310	COG4171	peptide transport system, permease
EHC68_11320	COG4172	Belongs to the ABC transporter superfamily
EHC68_11330	COG1227	inorganic diphosphatase activity
EHC68_11345	COG0243	molybdopterin cofactor binding
EHC68_11350	COG3005	denitrification pathway
EHC68_11355	COG4459	periplasmic nitrate reductase
EHC68_11360	COG0390	transport system, permease component
EHC68_11370	COG2116	formate transmembrane transporter activity
EHC68_11395	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC68_11400	COG1435	thymidine kinase activity
EHC68_11405	COG0215	cysteine-tRNA ligase activity
EHC68_11410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC68_11415	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EHC68_11420	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EHC68_11430	COG3012	SEC-C Motif Domain Protein
EHC68_11435	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EHC68_11435	COG0140	phosphoribosyl-ATP diphosphatase activity
EHC68_11440	COG0107	imidazoleglycerol-phosphate synthase activity
EHC68_11445	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EHC68_11450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EHC68_11455	COG0131	Imidazoleglycerol-phosphate dehydratase
EHC68_11455	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC68_11460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EHC68_11465	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EHC68_11470	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EHC68_11485	COG1757	Na H antiporter
EHC68_11495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC68_11505	COG0482	sulfurtransferase activity
EHC68_11510	COG2915	High frequency lysogenization protein hflD homolog
EHC68_11515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EHC68_11540	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EHC68_11555	COG0300	oxidoreductase activity
EHC68_11565	COG0501	Belongs to the peptidase M48B family
EHC68_11575	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EHC68_11585	COG0156	8-amino-7-oxononanoate synthase activity
EHC68_11590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EHC68_11595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC68_11600	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EHC68_11615	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EHC68_11620	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EHC68_11625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EHC68_11630	COG1674	ftsk spoiiie
EHC68_11640	COG0686	Belongs to the AlaDH PNT family
EHC68_11650	COG0583	DNA-binding transcription factor activity
EHC68_11665	COG3568	Endonuclease Exonuclease Phosphatase
EHC68_11695	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC68_11700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_11715	COG0840	transmembrane signaling receptor activity
EHC68_11785	COG5002	protein histidine kinase activity
EHC68_11785	COG0784	Response regulator, receiver
EHC68_11795	COG0754	glutathionylspermidine amidase activity
EHC68_11805	COG3766	membrane
EHC68_11815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EHC68_11820	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EHC68_11825	COG2885	chlorophyll binding
EHC68_11830	COG0823	Involved in the tonB-independent uptake of proteins
EHC68_11845	COG0811	peptide transport
EHC68_11850	COG0824	Thioesterase
EHC68_11860	COG4890	Cyd operon protein YbgT
EHC68_11865	COG1294	oxidase, subunit
EHC68_11870	COG1271	oxidase subunit
EHC68_11875	COG2255	four-way junction helicase activity
EHC68_11880	COG0632	four-way junction helicase activity
EHC68_11885	COG0840	transmembrane signaling receptor activity
EHC68_11890	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EHC68_11895	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EHC68_11900	COG1801	Protein of unknown function DUF72
EHC68_11905	COG4106	trans-aconitate 2-methyltransferase activity
EHC68_11910	COG0500	methyltransferase
EHC68_11920	COG4067	protein conserved in archaea
EHC68_11920	COG0189	ligase activity
EHC68_11940	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC68_11945	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EHC68_11950	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EHC68_11955	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC68_11960	COG1434	Gram-negative-bacterium-type cell wall biogenesis
EHC68_11965	COG0745	RESPONSE REGULATOR receiver
EHC68_11970	COG3381	protein complex oligomerization
EHC68_11975	COG1609	Transcriptional regulator
EHC68_11980	COG3070	regulator of competence-specific genes
EHC68_12000	COG0297	glycogen (starch) synthase activity
EHC68_12005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC68_12010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EHC68_12020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EHC68_12030	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EHC68_12035	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EHC68_12040	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EHC68_12050	COG0542	response to heat
EHC68_12055	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EHC68_12060	COG1278	Cold shock
EHC68_12070	COG1187	pseudouridine synthase activity
EHC68_12075	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC68_12085	COG1199	ATP-dependent helicase activity
EHC68_12090	COG0730	response to heat
EHC68_12095	COG3923	Primosomal replication protein n
EHC68_12105	COG0708	Exodeoxyribonuclease III
EHC68_12120	COG4215	(ABC) transporter
EHC68_12150	COG1882	Formate acetyltransferase
EHC68_12160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC68_12170	COG3013	Belongs to the UPF0304 family
EHC68_12180	COG2766	serine protein kinase
EHC68_12185	COG2718	Belongs to the UPF0229 family
EHC68_12190	COG2719	SpoVR family
EHC68_12195	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EHC68_12205	COG1663	tetraacyldisaccharide 4'-kinase activity
EHC68_12210	COG1132	(ABC) transporter
EHC68_12215	COG0658	competence protein
EHC68_12215	COG2333	competence protein COMEC
EHC68_12225	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC68_12230	COG1136	(ABC) transporter
EHC68_12235	COG4591	ABC-type transport system involved in lipoprotein release permease component
EHC68_12245	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EHC68_12260	COG1252	NADH dehydrogenase
EHC68_12270	COG3150	esterase
EHC68_12295	COG0537	adenosine 5'-monophosphoramidase activity
EHC68_12325	COG0516	GMP reductase activity
EHC68_12325	COG0517	IMP dehydrogenase activity
EHC68_12335	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EHC68_12340	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC68_12345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC68_12420	COG2199	diguanylate cyclase activity
EHC68_12435	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EHC68_12440	COG1946	Acyl-CoA thioesterase
EHC68_12450	COG1522	sequence-specific DNA binding
EHC68_12480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC68_12530	COG0477	Major facilitator Superfamily
EHC68_12535	COG2855	membrane
EHC68_12550	COG1441	menaquinone biosynthetic process
EHC68_12555	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EHC68_12560	COG0596	Alpha beta hydrolase
EHC68_12565	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EHC68_12570	COG1169	isochorismate synthase
EHC68_12575	COG0436	Aminotransferase
EHC68_12580	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
EHC68_12585	COG0232	Belongs to the dGTPase family. Type 2 subfamily
EHC68_12600	COG1555	photosystem II stabilization
EHC68_12605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC68_12610	COG0776	regulation of translation
EHC68_12615	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EHC68_12620	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EHC68_12630	COG0544	peptidyl-prolyl cis-trans isomerase activity
EHC68_12640	COG2204	response regulator
EHC68_12650	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EHC68_12655	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC68_12660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EHC68_12665	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EHC68_12685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC68_12690	COG0569	domain protein
EHC68_12695	COG0513	Belongs to the DEAD box helicase family
EHC68_12700	COG1253	flavin adenine dinucleotide binding
EHC68_12735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC68_12740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EHC68_12755	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC68_12760	COG1216	Glycosyl transferase, family 2
EHC68_12765	COG2986	histidine ammonia-lyase
EHC68_12790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EHC68_12795	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EHC68_12800	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_12820	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EHC68_12825	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC68_12830	COG0583	DNA-binding transcription factor activity
EHC68_12835	COG2951	lytic endotransglycosylase activity
EHC68_12840	COG3100	YcgL domain-containing protein
EHC68_12845	COG0850	regulation of cytokinetic process
EHC68_12850	COG2894	cell division
EHC68_12855	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EHC68_12860	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EHC68_12865	COG0318	PFAM AMP-dependent synthetase and ligase
EHC68_12870	COG2267	carboxylic ester hydrolase activity
EHC68_12885	COG1214	PFAM Peptidase M22, glycoprotease
EHC68_12890	COG1199	ATP-dependent helicase activity
EHC68_12895	COG0788	formyltetrahydrofolate deformylase activity
EHC68_12900	COG3102	Protein conserved in bacteria
EHC68_12910	COG0018	arginyl-trna synthetase
EHC68_12930	COG1918	ferrous iron import across plasma membrane
EHC68_12945	COG4977	sequence-specific DNA binding
EHC68_12950	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EHC68_12955	COG1121	(ABC) transporter
EHC68_12960	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC68_12970	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC68_12975	COG0508	dehydrogenase complex catalyzes the overall conversion of
EHC68_12980	COG0567	Dehydrogenase, E1 component
EHC68_12985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EHC68_12990	COG1053	succinate dehydrogenase
EHC68_12995	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EHC68_13000	COG2009	succinate dehydrogenase
EHC68_13010	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EHC68_13020	COG0033	Phosphoglucomutase
EHC68_13025	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EHC68_13030	COG0596	Alpha beta hydrolase
EHC68_13040	COG0716	FMN binding
EHC68_13050	COG0735	belongs to the Fur family
EHC68_13055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC68_13060	COG1263	PTS System
EHC68_13060	COG2190	(PTS) system
EHC68_13060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC68_13070	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EHC68_13075	COG1846	Transcriptional regulator
EHC68_13075	COG1940	carbohydrate kinase activity
EHC68_13080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EHC68_13080	COG4651	solute:proton antiporter activity
EHC68_13085	COG0367	asparagine synthase
EHC68_13090	COG0250	Participates in transcription elongation, termination and antitermination
EHC68_13095	COG3104	oligopeptide transport
EHC68_13100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EHC68_13105	COG0563	adenylate kinase activity
EHC68_13110	COG0326	Molecular chaperone. Has ATPase activity
EHC68_13115	COG3710	Transcriptional regulator
EHC68_13135	COG0622	Phosphoesterase
EHC68_13165	COG1090	epimerase
EHC68_13170	COG0300	oxidoreductase activity
EHC68_13180	COG3118	belongs to the thioredoxin family
EHC68_13185	COG0330	HflC and HflK could
EHC68_13210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EHC68_13215	COG3115	cell septum assembly
EHC68_13220	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EHC68_13225	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EHC68_13235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_13240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC68_13245	COG2190	(PTS) system
EHC68_13255	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_13260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_13270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_13280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_13290	COG1705	Flagellar rod assembly protein muramidase FlgJ
EHC68_13290	COG3951	Flagellar rod assembly protein muramidase FlgJ
EHC68_13295	COG1706	bacterial-type flagellum-dependent cell motility
EHC68_13300	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC68_13305	COG4786	Flagellar basal body rod
EHC68_13310	COG4787	bacterial-type flagellum-dependent cell motility
EHC68_13320	COG1749	Flagellar hook protein flgE
EHC68_13325	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC68_13330	COG1558	bacterial-type flagellum-dependent cell motility
EHC68_13335	COG1815	bacterial-type flagellum-dependent cell motility
EHC68_13340	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EHC68_13345	COG0784	Response regulator, receiver
EHC68_13345	COG0835	chemotaxis
EHC68_13405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EHC68_13410	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC68_13425	COG2217	Heavy metal translocating P-type atpase
EHC68_13425	COG2608	mercury ion transmembrane transporter activity
EHC68_13465	COG2840	Smr protein MutS2
EHC68_13470	COG1187	pseudouridine synthase activity
EHC68_13480	COG0737	Belongs to the 5'-nucleotidase family
EHC68_13485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EHC68_13490	COG2912	Transglutaminase-like superfamily
EHC68_13495	COG3094	Invasion gene expression up-regulator, SirB
EHC68_13500	COG2890	protein-(glutamine-N5) methyltransferase activity
EHC68_13505	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EHC68_13510	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EHC68_13520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EHC68_13525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EHC68_13530	COG0193	aminoacyl-tRNA hydrolase activity
EHC68_13535	COG0012	GTP binding
EHC68_13650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EHC68_13660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EHC68_13665	COG1702	phosphate starvation-inducible protein PhoH
EHC68_13670	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EHC68_13675	COG4535	Mg2 and Co2 transporter CorC
EHC68_13680	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EHC68_13685	COG2888	peptidyl-tyrosine sulfation
EHC68_13690	COG0495	leucyl-tRNA aminoacylation
EHC68_13695	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
EHC68_13700	COG1466	dna polymerase III delta subunit
EHC68_13705	COG0799	negative regulation of ribosome biogenesis
EHC68_13710	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EHC68_13715	COG0768	penicillin binding
EHC68_13720	COG0772	Belongs to the SEDS family
EHC68_13725	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EHC68_13730	COG1686	Belongs to the peptidase S11 family
EHC68_13735	COG2921	Belongs to the UPF0250 family
EHC68_13740	COG0321	lipoyl(octanoyl) transferase activity
EHC68_13745	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EHC68_13750	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC68_13755	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC68_13770	COG0366	Alpha amylase catalytic
EHC68_13775	COG1263	PTS System
EHC68_13775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC68_13785	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EHC68_13795	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EHC68_13800	COG2011	ABC-type metal ion transport system permease component
EHC68_13805	COG1464	Belongs to the NlpA lipoprotein family
EHC68_13810	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
EHC68_13820	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC68_13820	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EHC68_13830	COG3706	GGDEF domain
EHC68_13830	COG0745	RESPONSE REGULATOR receiver
EHC68_13835	COG1611	Belongs to the LOG family
EHC68_13840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC68_13850	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
EHC68_13855	COG2363	Small membrane protein
EHC68_13865	COG0583	DNA-binding transcription factor activity
EHC68_13870	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC68_13870	COG0301	tRNA thio-modification
EHC68_13875	COG2885	chlorophyll binding
EHC68_13880	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC68_13885	COG1722	exodeoxyribonuclease VII activity
EHC68_13890	COG0142	geranyltranstransferase activity
EHC68_13895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EHC68_13900	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EHC68_13905	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EHC68_13910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC68_13930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC68_13930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC68_13935	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EHC68_13940	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EHC68_13945	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EHC68_13960	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EHC68_13965	COG2252	PERMEase
EHC68_13970	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC68_13995	COG0047	phosphoribosylformylglycinamidine synthase activity
EHC68_13995	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EHC68_14000	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
EHC68_14010	COG0590	tRNA wobble adenosine to inosine editing
EHC68_14015	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EHC68_14055	COG0484	heat shock protein binding
EHC68_14060	COG0443	Heat shock 70 kDa protein
EHC68_14070	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EHC68_14075	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EHC68_14085	COG0497	DNA recombination
EHC68_14090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC68_14095	COG2914	Belongs to the UPF0125 (RnfH) family
EHC68_14100	COG2867	negative regulation of translational initiation
EHC68_14105	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EHC68_14115	COG0582	viral genome integration into host DNA
EHC68_14120	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EHC68_14130	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EHC68_14145	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EHC68_14165	COG0328	RNA-DNA hybrid ribonuclease activity
EHC68_14170	COG2003	Belongs to the UPF0758 family
EHC68_14215	COG0328	RNA-DNA hybrid ribonuclease activity
EHC68_14260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EHC68_14260	COG3153	acetyltransferase
EHC68_14280	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
EHC68_14285	COG2873	o-acetylhomoserine
EHC68_14325	COG1115	amino acid carrier protein
EHC68_14335	COG1584	GPR1 FUN34 yaaH family protein
EHC68_14350	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EHC68_14350	COG0519	Catalyzes the synthesis of GMP from XMP
EHC68_14355	COG0517	IMP dehydrogenase activity
EHC68_14355	COG0516	GMP reductase activity
EHC68_14360	COG1570	exodeoxyribonuclease VII activity
EHC68_14375	COG1160	GTP binding
EHC68_14380	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC68_14385	COG2976	Protein conserved in bacteria
EHC68_14390	COG0124	histidyl-tRNA synthetase
EHC68_14395	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EHC68_14410	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EHC68_14415	COG0105	UTP biosynthetic process
EHC68_14420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EHC68_14425	COG2975	iron-sulfur cluster assembly
EHC68_14430	COG0633	Ferredoxin
EHC68_14435	COG0443	Heat shock 70 kDa protein
EHC68_14440	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC68_14450	COG0822	iron-sulfur transferase activity
EHC68_14455	COG1104	cysteine desulfurase activity
EHC68_14470	COG0483	inositol monophosphate 1-phosphatase activity
EHC68_14480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC68_14485	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC68_14490	COG1862	Preprotein translocase
EHC68_14495	COG0343	queuine tRNA-ribosyltransferase activity
EHC68_14500	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EHC68_14515	COG0517	IMP dehydrogenase activity
EHC68_14525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EHC68_14535	COG0583	DNA-binding transcription factor activity
EHC68_14540	COG0450	alkyl hydroperoxide reductase
EHC68_14550	COG3142	Participates in the control of copper homeostasis
EHC68_14560	COG0704	Plays a role in the regulation of phosphate uptake
EHC68_14565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC68_14570	COG0581	inorganic phosphate transmembrane transporter activity
EHC68_14580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EHC68_14585	COG0248	Ppx GppA phosphatase
EHC68_14595	COG5002	protein histidine kinase activity
EHC68_14600	COG0745	RESPONSE REGULATOR receiver
EHC68_14610	COG2974	May be involved in recombination
EHC68_14620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHC68_14685	COG0542	response to heat
EHC68_14695	COG0564	pseudouridine synthase activity
EHC68_14700	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC68_14705	COG0741	lytic transglycosylase activity
EHC68_14710	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EHC68_14715	COG0077	Prephenate dehydratase
EHC68_14715	COG1605	Chorismate mutase
EHC68_14720	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
EHC68_14725	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EHC68_14735	COG0488	(ABC) transporter
EHC68_14750	COG0739	heme binding
EHC68_14755	COG0287	Prephenate dehydrogenase
EHC68_14755	COG1605	Chorismate mutase
EHC68_14760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC68_14765	COG1472	Belongs to the glycosyl hydrolase 3 family
EHC68_14770	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EHC68_14775	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC68_14790	COG1966	Carbon starvation protein
EHC68_14795	COG3275	phosphorelay sensor kinase activity
EHC68_14800	COG3279	Response regulator of the LytR AlgR family
EHC68_14805	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EHC68_14810	COG1047	Peptidyl-prolyl cis-trans
EHC68_14815	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EHC68_14820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC68_14825	COG0196	riboflavin kinase activity
EHC68_14830	COG0728	peptidoglycan biosynthetic process
EHC68_14835	COG0268	Binds directly to 16S ribosomal RNA
EHC68_14845	COG0640	Transcriptional regulator
EHC68_14855	COG0583	DNA-binding transcription factor activity
EHC68_14860	COG1283	sodium-dependent phosphate transmembrane transporter activity
EHC68_14870	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EHC68_14875	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EHC68_14880	COG0730	response to heat
EHC68_14890	COG0494	nUDIX hydrolase
EHC68_14900	COG3066	DNA modification
EHC68_14910	COG0667	Aldo Keto reductase
EHC68_14925	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EHC68_14935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EHC68_14940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC68_14950	COG0716	FMN binding
EHC68_14960	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
EHC68_14965	COG0513	Belongs to the DEAD box helicase family
EHC68_14970	COG3022	response to hydroperoxide
EHC68_14975	COG1115	amino acid carrier protein
EHC68_14990	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EHC68_15000	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
EHC68_15005	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
EHC68_15010	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EHC68_15015	COG0083	homoserine kinase activity
EHC68_15030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC68_15045	COG0745	RESPONSE REGULATOR receiver
EHC68_15055	COG0784	Response regulator, receiver
EHC68_15055	COG5002	protein histidine kinase activity
EHC68_15055	COG2198	Histidine kinase
EHC68_15060	COG4251	negative regulation of phosphorylation
EHC68_15060	COG2203	Gaf domain
EHC68_15060	COG5001	Diguanylate cyclase
EHC68_15060	COG3706	GGDEF domain
EHC68_15065	COG1242	4 iron, 4 sulfur cluster binding
EHC68_15070	COG0070	glutamate synthase
EHC68_15070	COG0069	glutamate synthase activity
EHC68_15070	COG0067	glutamate synthase
EHC68_15080	COG0070	glutamate synthase
EHC68_15080	COG0067	glutamate synthase
EHC68_15080	COG0069	glutamate synthase activity
EHC68_15085	COG0493	'glutamate synthase
EHC68_15095	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC68_15105	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC68_15110	COG2860	membrane
EHC68_15115	COG0583	DNA-binding transcription factor activity
EHC68_15120	COG0730	response to heat
EHC68_15135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EHC68_15140	COG0505	Belongs to the CarA family
EHC68_15145	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EHC68_15150	COG0494	nUDIX hydrolase
EHC68_15155	COG0653	protein targeting
EHC68_15165	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EHC68_15170	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EHC68_15175	COG0849	cell division
EHC68_15180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EHC68_15185	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC68_15190	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EHC68_15195	COG0772	Belongs to the SEDS family
EHC68_15200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EHC68_15205	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EHC68_15210	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EHC68_15215	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EHC68_15220	COG0768	penicillin binding
EHC68_15225	COG3116	cell division
EHC68_15230	COG0275	rRNA processing
EHC68_15245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EHC68_15255	COG0792	nuclease activity
EHC68_15260	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EHC68_15265	COG2823	Periplasmic or secreted lipoprotein
EHC68_15270	COG2969	positive regulation of protein catabolic process
EHC68_15275	COG0625	glutathione transferase activity
EHC68_15280	COG2857	Cytochrome c1
EHC68_15285	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EHC68_15290	COG0723	plastoquinol--plastocyanin reductase activity
EHC68_15295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EHC68_15300	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EHC68_15310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EHC68_15320	COG3105	Protein conserved in bacteria
EHC68_15330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EHC68_15335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EHC68_15340	COG0187	DNA topoisomerase II activity
EHC68_15345	COG3150	esterase
EHC68_15355	COG3151	Protein conserved in bacteria
EHC68_15360	COG0494	nUDIX hydrolase
EHC68_15365	COG1538	Outer membrane efflux protein
EHC68_15370	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
EHC68_15370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
EHC68_15375	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EHC68_15390	COG3025	triphosphatase activity
EHC68_15395	COG1392	Phosphate transport regulator
EHC68_15400	COG0306	phosphate transporter
EHC68_15405	COG4991	sh3 domain protein
EHC68_15415	COG3409	Peptidoglycan-binding domain 1 protein
EHC68_15415	COG3267	Type II secretory pathway component ExeA
EHC68_15420	COG0617	tRNA 3'-terminal CCA addition
EHC68_15425	COG1968	undecaprenyl-diphosphatase activity
EHC68_15430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EHC68_15435	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EHC68_15445	COG0596	Alpha beta hydrolase
EHC68_15450	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EHC68_15455	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EHC68_15460	COG1610	YqeY-like protein
EHC68_15465	COG0358	DNA primase activity
EHC68_15470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EHC68_15515	COG3550	peptidyl-serine autophosphorylation
EHC68_15535	COG1464	Belongs to the NlpA lipoprotein family
EHC68_15570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_15570	COG2213	PTS system mannitol-specific
EHC68_15575	COG0246	Mannitol dehydrogenase
EHC68_15580	COG3722	fumarate hydratase activity
EHC68_15590	COG5002	protein histidine kinase activity
EHC68_15605	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EHC68_15610	COG1349	DNA-binding transcription factor activity
EHC68_15620	COG0469	pyruvate kinase activity
EHC68_15630	COG3706	GGDEF domain
EHC68_15635	COG0440	acetolactate synthase activity
EHC68_15640	COG0028	Belongs to the TPP enzyme family
EHC68_15645	COG1022	Amp-dependent synthetase and ligase
EHC68_15650	COG0583	DNA-binding transcription factor activity
EHC68_15670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EHC68_15675	COG0473	3-isopropylmalate dehydrogenase activity
EHC68_15680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EHC68_15685	COG0066	3-isopropylmalate dehydratase activity
EHC68_15695	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EHC68_15700	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EHC68_15705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC68_15710	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EHC68_15715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EHC68_15720	COG2967	ApaG domain
EHC68_15725	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EHC68_15740	COG2966	Psort location CytoplasmicMembrane, score
EHC68_15745	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EHC68_15755	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EHC68_15760	COG0142	geranyltranstransferase activity
EHC68_15770	COG0039	L-malate dehydrogenase activity
EHC68_15805	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EHC68_15810	COG1178	ABC-type Fe3 transport system permease component
EHC68_15815	COG4143	(ABC) transporter
EHC68_15820	COG0163	prenyltransferase activity
EHC68_15825	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EHC68_15835	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EHC68_15840	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EHC68_15850	COG2105	PFAM AIG2 family protein
EHC68_15855	COG2911	Protein conserved in bacteria
EHC68_15860	COG0729	surface antigen
EHC68_15865	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC68_15875	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC68_15890	COG4181	ATPase activity
EHC68_15910	COG0529	Catalyzes the synthesis of activated sulfate
EHC68_15915	COG3273	potassium ion transport
EHC68_15915	COG0471	metal ion transport
EHC68_15925	COG2895	sulfate adenylyltransferase (ATP) activity
EHC68_15930	COG0175	sulfate reduction
EHC68_15935	COG1648	precorrin-2 dehydrogenase activity
EHC68_15935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHC68_15940	COG0737	Belongs to the 5'-nucleotidase family
EHC68_15950	COG0513	Belongs to the DEAD box helicase family
EHC68_15955	COG2153	protein acetylation
EHC68_15965	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC68_15975	COG0203	ribosomal protein L17
EHC68_15980	COG0202	RNA polymerase activity
EHC68_15990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EHC68_15995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EHC68_16005	COG0201	protein transport
EHC68_16010	COG0200	Binds to the 23S rRNA
EHC68_16015	COG1841	ribosomal large subunit assembly
EHC68_16030	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EHC68_16035	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EHC68_16040	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EHC68_16045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EHC68_16050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EHC68_16055	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EHC68_16060	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EHC68_16065	COG0255	Belongs to the universal ribosomal protein uL29 family
EHC68_16075	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EHC68_16080	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EHC68_16085	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EHC68_16090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EHC68_16100	COG0088	Forms part of the polypeptide exit tunnel
EHC68_16105	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EHC68_16115	COG0254	rRNA binding
EHC68_16125	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EHC68_16130	COG1609	Transcriptional regulator
EHC68_16140	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EHC68_16145	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EHC68_16160	COG2003	Belongs to the UPF0758 family
EHC68_16190	COG1575	Belongs to the MenA family. Type 1 subfamily
EHC68_16195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EHC68_16200	COG3074	FtsZ-dependent cytokinesis
EHC68_16210	COG1494	fructose-1,6-bisphosphatase
EHC68_16235	COG0149	triose-phosphate isomerase activity
EHC68_16240	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EHC68_16260	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EHC68_16280	COG0438	transferase activity, transferring glycosyl groups
EHC68_16300	COG1215	transferase activity, transferring glycosyl groups
EHC68_16305	COG0110	maltose O-acetyltransferase activity
EHC68_16315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EHC68_16365	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EHC68_16375	COG1560	Kdo2-lipid A biosynthetic process
EHC68_16380	COG0859	PFAM glycosyl transferase family 9
EHC68_16385	COG1519	Transferase
EHC68_16395	COG0297	glycogen (starch) synthase activity
EHC68_16395	COG0438	transferase activity, transferring glycosyl groups
EHC68_16415	COG2030	dehydratase
EHC68_16420	COG0110	maltose O-acetyltransferase activity
EHC68_16440	COG3642	lipopolysaccharide core region biosynthetic process
EHC68_16445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC68_16450	COG0859	PFAM glycosyl transferase family 9
EHC68_16455	COG0463	Glycosyl transferase, family 2
EHC68_16470	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EHC68_16475	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EHC68_16490	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EHC68_16495	COG2003	Belongs to the UPF0758 family
EHC68_16510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EHC68_16515	COG1309	transcriptional regulator
EHC68_16520	COG1560	Kdo2-lipid A biosynthetic process
EHC68_16525	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EHC68_16530	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EHC68_16535	COG1561	YicC-like family, N-terminal region
EHC68_16545	COG4608	Belongs to the ABC transporter superfamily
EHC68_16550	COG0444	Belongs to the ABC transporter superfamily
EHC68_16555	COG0747	negative chemotaxis
EHC68_16565	COG4174	ABC transporter (Permease)
EHC68_16590	COG0811	peptide transport
EHC68_16595	COG0848	biopolymer transport protein
EHC68_16610	COG0194	GDP metabolic process
EHC68_16615	COG1758	RNA polymerase activity
EHC68_16620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EHC68_16625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EHC68_16630	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EHC68_16640	COG2233	PERMEase
EHC68_16645	COG2205	protein histidine kinase activity
EHC68_16650	COG0745	RESPONSE REGULATOR receiver
EHC68_16660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC68_16670	COG2183	response to ionizing radiation
EHC68_16680	COG0596	Alpha beta hydrolase
EHC68_16685	COG1040	competence protein
EHC68_16690	COG0316	Belongs to the HesB IscA family
EHC68_16690	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EHC68_16695	COG0494	nUDIX hydrolase
EHC68_16700	COG1218	3'(2'),5'-bisphosphate nucleotidase
EHC68_16710	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC68_16715	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
EHC68_16720	COG3156	type II secretion system protein K
EHC68_16725	COG4795	General secretion pathway protein
EHC68_16730	COG2165	general secretion pathway protein
EHC68_16735	COG2165	general secretion pathway protein
EHC68_16740	COG2165	general secretion pathway protein
EHC68_16745	COG1459	type II secretion system
EHC68_16750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EHC68_16760	COG3031	protein transport across the cell outer membrane
EHC68_16765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EHC68_16770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EHC68_16775	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
EHC68_16785	COG0456	acetyltransferase
EHC68_16790	COG1490	D-aminoacyl-tRNA deacylase activity
EHC68_16795	COG1295	ribonuclease BN
EHC68_16815	COG0174	glutamine synthetase
EHC68_16825	COG3852	Histidine kinase
EHC68_16830	COG2204	response regulator
EHC68_16840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC68_16845	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EHC68_16880	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EHC68_16890	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC68_16890	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EHC68_16915	COG0084	hydrolase, TatD family'
EHC68_16925	COG0805	protein transport
EHC68_16935	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EHC68_16940	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC68_16945	COG3165	ubiquinone biosynthetic process from chorismate
EHC68_16950	COG2226	methyltransferase
EHC68_16955	COG1322	Protein conserved in bacteria
EHC68_16970	COG0628	permease
EHC68_17020	COG2823	Periplasmic or secreted lipoprotein
EHC68_17030	COG2081	HI0933 family
EHC68_17040	COG1528	Iron-storage protein
EHC68_17045	COG0589	response to stress
EHC68_17050	COG0697	spore germination
EHC68_17060	COG0742	ribosomal rna small subunit methyltransferase
EHC68_17065	COG5002	protein histidine kinase activity
EHC68_17065	COG5001	Diguanylate cyclase
EHC68_17070	COG1522	sequence-specific DNA binding
EHC68_17075	COG0339	signal peptide processing
EHC68_17085	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EHC68_17090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EHC68_17095	COG0583	DNA-binding transcription factor activity
EHC68_17100	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EHC68_17105	COG0800	Aldolase
EHC68_17110	COG2610	gluconate transmembrane transporter activity
EHC68_17115	COG3265	gluconokinase activity
EHC68_17120	COG0129	dihydroxy-acid dehydratase activity
EHC68_17125	COG2076	Multidrug Resistance protein
EHC68_17135	COG0583	DNA-binding transcription factor activity
EHC68_17140	COG1609	Transcriptional regulator
EHC68_17180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EHC68_17190	COG0747	negative chemotaxis
EHC68_17195	COG4172	Belongs to the ABC transporter superfamily
EHC68_17260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_17265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC68_17275	COG2960	long-chain fatty acid transporting porin activity
EHC68_17280	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EHC68_17285	COG0583	DNA-binding transcription factor activity
EHC68_17330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EHC68_17340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EHC68_17345	COG0408	coproporphyrinogen oxidase activity
EHC68_17350	COG0009	L-threonylcarbamoyladenylate synthase
EHC68_17355	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EHC68_17360	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EHC68_17365	COG0551	DNA topoisomerase type I activity
EHC68_17370	COG2922	Belongs to the Smg family
EHC68_17385	COG0242	peptide deformylase activity
EHC68_17390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EHC68_17395	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EHC68_17395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EHC68_17400	COG0569	domain protein
EHC68_17405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EHC68_17415	COG1272	protein, Hemolysin III
EHC68_17420	COG4326	sporulation control protein
EHC68_17430	COG3084	Protein conserved in bacteria
EHC68_17440	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EHC68_17445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC68_17450	COG0204	Acyl-transferase
EHC68_17460	COG0606	chelatase, subunit chli
EHC68_17470	COG3978	acetolactate synthase activity
EHC68_17475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EHC68_17480	COG0129	dihydroxy-acid dehydratase activity
EHC68_17490	COG0583	DNA-binding transcription factor activity
EHC68_17495	COG2814	Major facilitator Superfamily
EHC68_17500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_17505	COG0765	amino acid transport
EHC68_17510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EHC68_17515	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EHC68_17520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EHC68_17525	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EHC68_17530	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EHC68_17535	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EHC68_17550	COG0356	it plays a direct role in the translocation of protons across the membrane
EHC68_17555	COG3312	ion transport
EHC68_17560	COG1475	DNA binding
EHC68_17565	COG1192	Involved in chromosome partitioning
EHC68_17570	COG0357	Ribosomal RNA small subunit methyltransferase G
EHC68_17575	COG0445	tRNA wobble uridine modification
EHC68_17595	COG1395	domain, Protein
EHC68_17620	COG0482	sulfurtransferase activity
EHC68_17635	COG1104	cysteine desulfurase activity
EHC68_17665	COG4974	Belongs to the 'phage' integrase family
EHC68_17670	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EHC68_17675	COG0706	membrane insertase activity
EHC68_17680	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EHC68_17685	COG0594	ribonuclease P activity
EHC68_17695	COG1126	abc transporter atp-binding protein
EHC68_17760	COG3547	Transposase (IS116 IS110 IS902 family)
EHC68_17790	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EHC68_17855	COG3547	Transposase (IS116 IS110 IS902 family)
EHC68_17900	COG1349	DNA-binding transcription factor activity
EHC68_17905	COG0738	Major facilitator superfamily
EHC68_17920	COG4154	Belongs to the RbsD FucU family
EHC68_17925	COG0235	Class ii aldolase
EHC68_17940	COG2003	Belongs to the UPF0758 family
EHC68_17975	COG0641	radical SAM
EHC68_17990	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
EHC68_18020	COG3069	C4-dicarboxylate transmembrane transporter activity
EHC68_18025	COG1704	LemA family
EHC68_18030	COG0501	Belongs to the peptidase M48B family
EHC68_18060	COG0641	radical SAM
EHC68_18080	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC68_18085	COG1597	lipid kinase activity
EHC68_18090	COG0583	DNA-binding transcription factor activity
EHC68_18095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EHC68_18125	COG0714	Associated with various cellular activities
EHC68_18130	COG0641	radical SAM
EHC68_18135	COG3119	arylsulfatase activity
EHC68_18150	COG3119	arylsulfatase activity
EHC68_18155	COG3119	arylsulfatase activity
EHC68_18160	COG0745	RESPONSE REGULATOR receiver
EHC68_18175	COG2205	protein histidine kinase activity
EHC68_18175	COG2198	Histidine kinase
EHC68_18175	COG0784	Response regulator, receiver
EHC68_18180	COG1879	ABC-type sugar transport system periplasmic component
EHC68_18185	COG1803	Methylglyoxal synthase
EHC68_18190	COG0210	DNA helicase
EHC68_18195	COG1289	transmembrane transporter activity
EHC68_18230	COG1629	transport
EHC68_18230	COG4771	TonB-dependent receptor
EHC68_18245	COG0789	Transcriptional regulator
EHC68_18250	COG4604	ABC transporter, ATP-binding protein
EHC68_18255	COG4605	iron ion homeostasis
EHC68_18260	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC68_18265	COG4607	ABC-type enterochelin transport system periplasmic component
EHC68_18295	COG0443	Heat shock 70 kDa protein
EHC68_18330	COG0625	glutathione transferase activity
EHC68_18345	COG4160	amino acid transport
EHC68_18350	COG4215	(ABC) transporter
EHC68_18355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_18360	COG1126	abc transporter atp-binding protein
EHC68_18405	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_18425	COG1902	pentaerythritol trinitrate reductase activity
EHC68_18430	COG0109	protoheme IX farnesyltransferase activity
EHC68_18435	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EHC68_18440	COG1845	cytochrome c oxidase, subunit III
EHC68_18445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EHC68_18450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC68_18455	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_18465	COG1024	Enoyl-CoA hydratase
EHC68_18470	COG1024	Enoyl-CoA hydratase
EHC68_18485	COG0183	Belongs to the thiolase family
EHC68_18495	COG1960	acyl-CoA dehydrogenase activity
EHC68_18500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHC68_18505	COG1024	Enoyl-CoA hydratase
EHC68_18515	COG5413	integral membrane protein
EHC68_18530	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EHC68_18540	COG5001	Diguanylate cyclase
EHC68_18545	COG0513	Belongs to the DEAD box helicase family
EHC68_18550	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
EHC68_18565	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC68_18585	COG0641	radical SAM
EHC68_18620	COG0840	transmembrane signaling receptor activity
EHC68_18625	COG1119	ATPase activity
EHC68_18630	COG2200	EAL domain
EHC68_18650	COG0513	Belongs to the DEAD box helicase family
EHC68_18655	COG0523	cobalamin synthesis protein
EHC68_18665	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EHC68_18675	COG0133	tryptophan synthase activity
EHC68_18680	COG4628	conserved protein (DUF2132)
EHC68_18685	COG0513	Belongs to the DEAD box helicase family
EHC68_18690	COG3530	Putative quorum-sensing-regulated virulence factor
EHC68_18715	COG2154	pterin-4-alpha-carbinolamine dehydratase
EHC68_18720	COG3186	Phenylalanine-4-hydroxylase
EHC68_18725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC68_18730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EHC68_18770	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EHC68_18780	COG2133	pyrroloquinoline quinone binding
EHC68_18790	COG0783	Belongs to the Dps family
EHC68_18795	COG0840	transmembrane signaling receptor activity
EHC68_18805	COG1136	(ABC) transporter
EHC68_18805	COG0577	efflux transmembrane transporter activity
EHC68_18825	COG2199	diguanylate cyclase activity
EHC68_18840	COG3036	rescue of stalled ribosome
EHC68_18845	COG1278	Cold shock
EHC68_18880	COG0545	Peptidyl-prolyl cis-trans isomerase
EHC68_18885	COG0109	protoheme IX farnesyltransferase activity
EHC68_18890	COG1612	heme a metabolic process
EHC68_18915	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EHC68_18925	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EHC68_18930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EHC68_18940	COG1280	lysine exporter protein (LysE YggA)
EHC68_18945	COG2207	Transcriptional regulator
EHC68_18975	COG0697	spore germination
EHC68_19000	COG2814	Major facilitator Superfamily
EHC68_19005	COG0583	DNA-binding transcription factor activity
EHC68_19010	COG5001	Diguanylate cyclase
EHC68_19015	COG0739	heme binding
EHC68_19075	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC68_19080	COG1072	(Pantothenic acid kinase))
EHC68_19090	COG1063	alcohol dehydrogenase
EHC68_19095	COG2213	PTS system mannitol-specific
EHC68_19100	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_19120	COG0798	PFAM Bile acid sodium symporter
EHC68_19130	COG1881	PFAM PEBP family protein
EHC68_19140	COG2706	6-phosphogluconolactonase activity
EHC68_19150	COG0840	transmembrane signaling receptor activity
EHC68_19160	COG1131	(ABC) transporter
EHC68_19165	COG0842	Transport permease protein
EHC68_19180	COG3383	formate dehydrogenase (NAD+) activity
EHC68_19225	COG2199	diguanylate cyclase activity
EHC68_19225	COG2203	Gaf domain
EHC68_19235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC68_19245	COG2067	long-chain fatty acid transport protein
EHC68_19255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_19265	COG1505	serine-type exopeptidase activity
EHC68_19270	COG0488	(ABC) transporter
EHC68_19275	COG0589	response to stress
EHC68_19280	COG2249	NAD(P)H dehydrogenase (quinone) activity
EHC68_19300	COG0366	Alpha amylase catalytic
EHC68_19310	COG4934	collagen metabolic process
EHC68_19325	COG0583	DNA-binding transcription factor activity
EHC68_19335	COG0783	Belongs to the Dps family
EHC68_19340	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC68_19365	COG0494	nUDIX hydrolase
EHC68_19380	COG3458	cephalosporin-C deacetylase activity
EHC68_19400	COG2814	Major facilitator Superfamily
EHC68_19415	COG0328	RNA-DNA hybrid ribonuclease activity
EHC68_19445	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EHC68_19450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EHC68_19460	COG0835	chemotaxis
EHC68_19460	COG0784	Response regulator, receiver
EHC68_19470	COG0748	coenzyme F420 binding
EHC68_19475	COG3721	Heme iron utilization protein
EHC68_19485	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EHC68_19490	COG0811	peptide transport
EHC68_19495	COG0848	biopolymer transport protein
EHC68_19505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC68_19510	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EHC68_19555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EHC68_19560	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EHC68_19565	COG0633	Ferredoxin
EHC68_19565	COG3217	Mosc domain protein beta barrel domain protein
EHC68_19565	COG0633	Ferredoxin
EHC68_19565	COG3217	Mosc domain protein beta barrel domain protein
EHC68_19575	COG0401	homolog of Blt101
EHC68_19585	COG0418	dihydroorotase activity
EHC68_19590	COG2354	Protein conserved in bacteria
EHC68_19620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EHC68_19620	COG2207	Transcriptional regulator
EHC68_19625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC68_19670	COG0513	Belongs to the DEAD box helicase family
EHC68_19680	COG0583	DNA-binding transcription factor activity
EHC68_19695	COG1902	pentaerythritol trinitrate reductase activity
EHC68_19700	COG1063	alcohol dehydrogenase
EHC68_19710	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_19725	COG3122	Protein conserved in bacteria
EHC68_19755	COG0583	DNA-binding transcription factor activity
EHC68_19765	COG0252	asparaginase activity
EHC68_19770	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EHC68_19775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EHC68_19775	COG0574	Belongs to the PEP-utilizing enzyme family
EHC68_19795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EHC68_19800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EHC68_19815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_19835	COG3706	GGDEF domain
EHC68_19855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EHC68_19885	COG3842	ATPase activity
EHC68_19920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EHC68_19970	COG0583	DNA-binding transcription factor activity
EHC68_19980	COG4948	Mandelate Racemase Muconate Lactonizing
EHC68_19990	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EHC68_20015	COG1342	Belongs to the UPF0251 family
EHC68_20025	COG3015	lipoprotein NlpE involved in copper resistance
EHC68_20035	COG3713	MltA-interacting MipA family protein
EHC68_20050	COG0583	DNA-binding transcription factor activity
EHC68_20080	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EHC68_20090	COG1335	isochorismatase
EHC68_20100	COG0753	catalase activity
EHC68_20110	COG1349	DNA-binding transcription factor activity
EHC68_20115	COG0346	lactoylglutathione lyase activity
EHC68_20130	COG0583	DNA-binding transcription factor activity
EHC68_20140	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_20145	COG2070	2-Nitropropane dioxygenase
EHC68_20150	COG0737	Belongs to the 5'-nucleotidase family
EHC68_20160	COG1309	transcriptional regulator
EHC68_20180	COG1280	lysine exporter protein (LysE YggA)
EHC68_20195	COG0459	protein refolding
EHC68_20200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EHC68_20205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EHC68_20230	COG1304	FMN binding
EHC68_20250	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_20255	COG1256	bacterial-type flagellum assembly
EHC68_20255	COG4786	Flagellar basal body rod
EHC68_20265	COG1706	bacterial-type flagellum-dependent cell motility
EHC68_20270	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EHC68_20275	COG4786	Flagellar basal body rod
EHC68_20280	COG4787	bacterial-type flagellum-dependent cell motility
EHC68_20285	COG1749	Flagellar hook protein flgE
EHC68_20290	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EHC68_20295	COG1558	bacterial-type flagellum-dependent cell motility
EHC68_20300	COG1815	bacterial-type flagellum-dependent cell motility
EHC68_20320	COG0741	lytic transglycosylase activity
EHC68_20325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EHC68_20345	COG1760	l-serine dehydratase
EHC68_20370	COG0583	DNA-binding transcription factor activity
EHC68_20385	COG2866	Carboxypeptidase
EHC68_20390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EHC68_20400	COG2990	Protein conserved in bacteria
EHC68_20425	COG3842	ATPase activity
EHC68_20435	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC68_20450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC68_20455	COG1609	Transcriptional regulator
EHC68_20485	COG3240	lipase activity
EHC68_20500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EHC68_20505	COG2067	long-chain fatty acid transport protein
EHC68_20515	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EHC68_20530	COG1011	Hydrolase
EHC68_20570	COG0110	maltose O-acetyltransferase activity
EHC68_20575	COG1765	OsmC-like protein
EHC68_20580	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC68_20580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EHC68_20595	COG3046	protein related to deoxyribodipyrimidine photolyase
EHC68_20600	COG0415	Belongs to the DNA photolyase family
EHC68_20605	COG3706	GGDEF domain
EHC68_20620	COG0840	transmembrane signaling receptor activity
EHC68_20625	COG3706	GGDEF domain
EHC68_20630	COG3145	DNA-N1-methyladenine dioxygenase activity
EHC68_20640	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EHC68_20660	COG3033	Beta-eliminating lyase
EHC68_20670	COG0579	oxidoreductase
EHC68_20700	COG3706	GGDEF domain
EHC68_20710	COG4191	Histidine kinase
EHC68_20745	COG0583	DNA-binding transcription factor activity
EHC68_20750	COG0189	ligase activity
EHC68_20755	COG0189	ligase activity
EHC68_20755	COG4067	protein conserved in archaea
EHC68_20765	COG1166	arginine decarboxylase activity
EHC68_20770	COG0010	Belongs to the arginase family
EHC68_20775	COG2814	Major facilitator Superfamily
EHC68_20780	COG1770	oligopeptidase
EHC68_20795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EHC68_20800	COG1121	(ABC) transporter
EHC68_20805	COG0803	Belongs to the bacterial solute-binding protein 9 family
EHC68_20845	COG0848	biopolymer transport protein
EHC68_20850	COG0811	peptide transport
EHC68_20855	COG0811	peptide transport
EHC68_20875	COG0745	RESPONSE REGULATOR receiver
EHC68_20885	COG0584	glycerophosphoryl diester phosphodiesterase
EHC68_20895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EHC68_20960	COG1901	pseudouridine methyltransferase
EHC68_20965	COG0312	modulator of DNA gyrase
EHC68_20980	COG0351	phosphomethylpyrimidine kinase
EHC68_20985	COG1116	anion transmembrane transporter activity
EHC68_20990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC68_20995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC68_21000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EHC68_21005	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
EHC68_21010	COG0352	thiamine-phosphate diphosphorylase activity
EHC68_21020	COG0243	molybdopterin cofactor binding
EHC68_21025	COG3005	denitrification pathway
EHC68_21035	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_21050	COG0456	acetyltransferase
EHC68_21070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC68_21075	COG1929	Belongs to the glycerate kinase type-1 family
EHC68_21080	COG2610	gluconate transmembrane transporter activity
EHC68_21085	COG3835	regulator
EHC68_21125	COG0583	DNA-binding transcription factor activity
EHC68_21140	COG0641	radical SAM
EHC68_21145	COG0583	DNA-binding transcription factor activity
EHC68_21155	COG0583	DNA-binding transcription factor activity
EHC68_21165	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EHC68_21170	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
EHC68_21170	COG3408	Glycogen debranching enzyme
EHC68_21200	COG3047	cAMP biosynthetic process
EHC68_21205	COG1357	PFAM Pentapeptide repeats (8 copies)
EHC68_21235	COG2375	cellular response to nickel ion
EHC68_21240	COG0823	Involved in the tonB-independent uptake of proteins
EHC68_21245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC68_21265	COG0800	Aldolase
EHC68_21270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC68_21285	COG1917	Cupin 2, conserved barrel domain protein
EHC68_21295	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_21300	COG1414	Transcriptional regulator
EHC68_21315	COG0583	DNA-binding transcription factor activity
EHC68_21320	COG2162	N-hydroxyarylamine O-acetyltransferase activity
EHC68_21325	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EHC68_21340	COG2199	diguanylate cyclase activity
EHC68_21350	COG0561	phosphatase activity
EHC68_21355	COG0583	DNA-binding transcription factor activity
EHC68_21370	COG0564	pseudouridine synthase activity
EHC68_21375	COG0534	Mate efflux family protein
EHC68_21385	COG5001	Diguanylate cyclase
EHC68_21395	COG3123	guanosine phosphorylase activity
EHC68_21435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
EHC68_21445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EHC68_21450	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EHC68_21465	COG2259	Doxx family
EHC68_21470	COG1741	Belongs to the pirin family
EHC68_21490	COG0363	glucosamine-6-phosphate deaminase activity
EHC68_21505	COG0786	glutamate:sodium symporter activity
EHC68_21510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC68_21515	COG1131	(ABC) transporter
EHC68_21525	COG0786	glutamate:sodium symporter activity
EHC68_21560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EHC68_21570	COG3279	Response regulator of the LytR AlgR family
EHC68_21575	COG3275	phosphorelay sensor kinase activity
EHC68_21595	COG1136	(ABC) transporter
EHC68_21610	COG0772	Belongs to the SEDS family
EHC68_21615	COG0217	transcriptional regulatory protein
EHC68_21640	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC68_21640	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EHC68_21650	COG0444	Belongs to the ABC transporter superfamily
EHC68_21655	COG4608	Belongs to the ABC transporter superfamily
EHC68_21680	COG1444	tRNA N-acetyltransferase activity
EHC68_21700	COG3340	Belongs to the peptidase S51 family
EHC68_21705	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EHC68_21710	COG1263	PTS System
EHC68_21710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC68_21715	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EHC68_21735	COG4166	transmembrane transport
EHC68_21790	COG0259	pyridoxamine-phosphate oxidase activity
EHC68_21820	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EHC68_21865	COG1132	(ABC) transporter
EHC68_21875	COG2207	Transcriptional regulator
EHC68_21900	COG0800	Aldolase
EHC68_21905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC68_21910	COG1904	glucuronate isomerase
EHC68_21915	COG0246	Mannitol dehydrogenase
EHC68_21925	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EHC68_21935	COG2186	Transcriptional regulator
EHC68_21940	COG1312	Catalyzes the dehydration of D-mannonate
EHC68_21945	COG0513	Belongs to the DEAD box helicase family
EHC68_21950	COG2258	MOSC domain
EHC68_21965	COG1486	melibiose metabolic process
EHC68_21970	COG0583	DNA-binding transcription factor activity
EHC68_21975	COG0840	transmembrane signaling receptor activity
EHC68_21990	COG1595	DNA-templated transcription, initiation
EHC68_22025	COG3634	alkyl hydroperoxide reductase activity
EHC68_22030	COG0450	alkyl hydroperoxide reductase
EHC68_22035	COG1846	Transcriptional regulator
EHC68_22040	COG1764	response to oxidative stress
EHC68_22065	COG2160	L-arabinose isomerase activity
EHC68_22075	COG1069	ribulokinase activity
EHC68_22080	COG1879	ABC-type sugar transport system periplasmic component
EHC68_22085	COG1129	ABC transporter
EHC68_22090	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC68_22115	COG0745	RESPONSE REGULATOR receiver
EHC68_22125	COG1653	transport
EHC68_22130	COG0019	diaminopimelate decarboxylase activity
EHC68_22135	COG4264	IucA IucC family
EHC68_22160	COG4772	TonB-dependent receptor
EHC68_22165	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC68_22170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC68_22175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EHC68_22180	COG1120	ATPase activity
EHC68_22185	COG0840	transmembrane signaling receptor activity
EHC68_22190	COG0612	Peptidase, M16
EHC68_22200	COG0739	heme binding
EHC68_22225	COG4580	involved in the transport of maltose and maltodextrins
EHC68_22250	COG2356	endonuclease I
EHC68_22270	COG1982	Orn Lys Arg decarboxylase major
EHC68_22275	COG0531	amino acid
EHC68_22285	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
EHC68_22295	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
EHC68_22300	COG1162	GTPase activity
EHC68_22305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EHC68_22305	COG1263	PTS System
EHC68_22315	COG1999	signal sequence binding
EHC68_22330	COG2909	trisaccharide binding
EHC68_22345	COG0058	SHG alpha-glucan phosphorylase activity
EHC68_22350	COG1640	4-alpha-glucanotransferase
EHC68_22355	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EHC68_22360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EHC68_22365	COG0366	Alpha amylase catalytic
EHC68_22380	COG3366	ferrous iron transmembrane transporter activity
EHC68_22385	COG0700	Nucleoside recognition
EHC68_22390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EHC68_22395	COG3339	Conserved Protein
EHC68_22400	COG1301	dicarboxylic acid transport
EHC68_22410	COG0583	DNA-binding transcription factor activity
EHC68_22425	COG0489	protein tyrosine kinase activity
EHC68_22425	COG3206	protein involved in exopolysaccharide biosynthesis
EHC68_22445	COG2095	MarC family integral membrane protein
EHC68_22450	COG4667	esterase of the alpha-beta hydrolase superfamily
EHC68_22455	COG3397	chitin binding
EHC68_22475	COG1686	Belongs to the peptidase S11 family
EHC68_22500	COG0583	DNA-binding transcription factor activity
EHC68_22505	COG4628	conserved protein (DUF2132)
EHC68_22515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EHC68_22525	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EHC68_22530	COG0628	permease
EHC68_22550	COG1538	Outer membrane efflux protein
EHC68_22575	COG2814	Major facilitator Superfamily
EHC68_22590	COG0454	-acetyltransferase
EHC68_22600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC68_22605	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EHC68_22640	COG1360	Flagellar Motor Protein
EHC68_22645	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
EHC68_22650	COG1191	sigma factor activity
EHC68_22655	COG1580	Controls the rotational direction of flagella during chemotaxis
EHC68_22670	COG1516	flagellar protein fliS
EHC68_22685	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
EHC68_22700	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EHC68_22710	COG1987	bacterial-type flagellum assembly
EHC68_22735	COG2204	response regulator
EHC68_22750	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EHC68_22790	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
EHC68_22810	COG0346	lactoylglutathione lyase activity
EHC68_22845	COG0745	RESPONSE REGULATOR receiver
EHC68_22865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_22875	COG0156	8-amino-7-oxononanoate synthase activity
EHC68_22880	COG1063	alcohol dehydrogenase
EHC68_22920	COG0668	transmembrane transport
EHC68_22930	COG1304	FMN binding
EHC68_22935	COG1620	l-lactate permease
EHC68_22940	COG0583	DNA-binding transcription factor activity
EHC68_22945	COG1505	serine-type exopeptidase activity
EHC68_22950	COG4172	Belongs to the ABC transporter superfamily
EHC68_22960	COG1067	ATP-dependent peptidase activity
EHC68_22990	COG1247	-acetyltransferase
EHC68_22995	COG0437	4 iron, 4 sulfur cluster binding
EHC68_23000	COG0348	domain, Protein
EHC68_23015	COG1122	ATPase activity
EHC68_23020	COG4720	Psort location CytoplasmicMembrane, score
EHC68_23025	COG1566	PFAM secretion protein HlyD family protein
EHC68_23035	COG3706	GGDEF domain
EHC68_23050	COG0813	purine-nucleoside phosphorylase activity
EHC68_23060	COG3272	Protein of unknown function (DUF1722)
EHC68_23065	COG0789	Transcriptional regulator
EHC68_23070	COG0415	Belongs to the DNA photolyase family
EHC68_23075	COG1388	LysM domain
EHC68_23075	COG1376	ErfK ybiS ycfS ynhG family protein
EHC68_23085	COG0513	Belongs to the DEAD box helicase family
EHC68_23090	COG1770	oligopeptidase
EHC68_23095	COG4771	TonB-dependent receptor
EHC68_23120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EHC68_23125	COG0573	inorganic phosphate transmembrane transporter activity
EHC68_23130	COG0581	inorganic phosphate transmembrane transporter activity
EHC68_23135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EHC68_23150	COG2304	oxidoreductase activity
EHC68_23170	COG0714	Associated with various cellular activities
EHC68_23180	COG0840	transmembrane signaling receptor activity
EHC68_23190	COG2197	response regulator
EHC68_23240	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EHC68_23245	COG1120	ATPase activity
EHC68_23250	COG4774	siderophore transport
EHC68_23255	COG1132	(ABC) transporter
EHC68_23260	COG5002	protein histidine kinase activity
EHC68_23270	COG0569	domain protein
EHC68_23285	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
EHC68_23290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC68_23305	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_23305	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_23305	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_23310	COG2207	Transcriptional regulator
EHC68_23320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_23325	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_23330	COG2084	Dehydrogenase
EHC68_23335	COG0753	catalase activity
EHC68_23345	COG2130	NADP-dependent
EHC68_23350	COG1309	transcriptional regulator
EHC68_23385	COG0438	transferase activity, transferring glycosyl groups
EHC68_23415	COG3842	ATPase activity
EHC68_23425	COG1175	transmembrane transport
EHC68_23430	COG3833	ABC-type maltose transport systems, permease component
EHC68_23450	COG3746	phosphate-selective porin O and P
EHC68_23470	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_23505	COG0625	glutathione transferase activity
EHC68_23520	COG1686	Belongs to the peptidase S11 family
EHC68_23540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EHC68_23560	COG1278	Cold shock
EHC68_23565	COG1741	Belongs to the pirin family
EHC68_23580	COG1846	Transcriptional regulator
EHC68_23595	COG2814	Major facilitator Superfamily
EHC68_23605	COG0673	inositol 2-dehydrogenase activity
EHC68_23610	COG2194	sulfuric ester hydrolase activity
EHC68_23615	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EHC68_23625	COG2205	protein histidine kinase activity
EHC68_23630	COG0745	RESPONSE REGULATOR receiver
EHC68_23635	COG4221	oxidoreductase activity
EHC68_23655	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC68_23675	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EHC68_23685	COG2814	Major facilitator Superfamily
EHC68_23700	COG1418	mRNA catabolic process
EHC68_23710	COG0402	S-adenosylhomocysteine deaminase activity
EHC68_23715	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EHC68_23725	COG2239	Acts as a magnesium transporter
EHC68_23730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EHC68_23745	COG0531	amino acid
EHC68_23755	COG1522	sequence-specific DNA binding
EHC68_23785	COG0673	inositol 2-dehydrogenase activity
EHC68_23790	COG0534	Mate efflux family protein
EHC68_23795	COG2926	Belongs to the UPF0265 family
EHC68_23810	COG3132	Protein of unknown function, DUF480
EHC68_23815	COG2827	Endonuclease containing a URI domain
EHC68_23820	COG1879	ABC-type sugar transport system periplasmic component
EHC68_23825	COG0784	Response regulator, receiver
EHC68_23825	COG2205	protein histidine kinase activity
EHC68_23835	COG1566	PFAM secretion protein HlyD family protein
EHC68_23855	COG1522	sequence-specific DNA binding
EHC68_23885	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC68_23890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EHC68_23910	COG0183	Belongs to the thiolase family
EHC68_23930	COG3005	denitrification pathway
EHC68_23940	COG0243	molybdopterin cofactor binding
EHC68_23950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EHC68_23955	COG3850	Histidine kinase
EHC68_23960	COG2197	response regulator
EHC68_23975	COG2195	Cleaves the N-terminal amino acid of tripeptides
EHC68_23995	COG0840	transmembrane signaling receptor activity
EHC68_24005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EHC68_24020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EHC68_24025	COG2814	Major facilitator Superfamily
EHC68_24035	COG0840	transmembrane signaling receptor activity
EHC68_24040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EHC68_24045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EHC68_24075	COG2897	thiosulfate sulfurtransferase activity
EHC68_24095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EHC68_24105	COG0302	gtp cyclohydrolase
EHC68_24110	COG1914	H( )-stimulated, divalent metal cation uptake system
EHC68_24120	COG0038	chloride channel
EHC68_24135	COG4989	oxidoreductase activity
EHC68_24150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EHC68_24150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EHC68_24155	COG0516	GMP reductase activity
EHC68_24160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EHC68_24220	COG0500	methyltransferase
EHC68_24230	COG3474	cytochrome
EHC68_24240	COG0789	Transcriptional regulator
EHC68_24245	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EHC68_24250	COG0384	phenazine biosynthesis protein PhzF
EHC68_24260	COG1294	oxidase, subunit
EHC68_24265	COG1271	oxidase subunit
EHC68_24270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EHC68_24275	COG0110	maltose O-acetyltransferase activity
EHC68_24285	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
EHC68_24285	COG3264	Mechanosensitive ion channel
EHC68_24300	COG3437	response regulator, receiver
EHC68_24300	COG2205	protein histidine kinase activity
EHC68_24300	COG3850	Histidine kinase
EHC68_24300	COG4999	Histidine kinase
EHC68_24320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EHC68_24325	COG1960	acyl-CoA dehydrogenase activity
EHC68_24335	COG0183	Belongs to the thiolase family
EHC68_24345	COG1960	acyl-CoA dehydrogenase activity
EHC68_24350	COG1024	Enoyl-CoA hydratase
EHC68_24365	COG1028	Short-chain dehydrogenase reductase Sdr
EHC68_24375	COG3706	GGDEF domain
EHC68_24380	COG1309	transcriptional regulator
EHC68_24385	COG1012	belongs to the aldehyde dehydrogenase family
EHC68_24400	COG4176	ABC-type proline glycine betaine transport system permease component
EHC68_24405	COG4175	Glycine betaine
EHC68_24405	COG0517	IMP dehydrogenase activity
EHC68_24420	COG0330	HflC and HflK could
EHC68_24430	COG5001	Diguanylate cyclase
EHC68_24430	COG3300	MHYT domain
EHC68_24450	COG2205	protein histidine kinase activity
EHC68_24450	COG0784	Response regulator, receiver
EHC68_24510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EHC68_24515	COG5001	Diguanylate cyclase
EHC68_24520	COG1869	D-ribose catabolic process
EHC68_24525	COG1129	ABC transporter
EHC68_24530	COG1172	Belongs to the binding-protein-dependent transport system permease family
EHC68_24535	COG1879	ABC-type sugar transport system periplasmic component
EHC68_24540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC68_24545	COG1609	Transcriptional regulator
EHC68_24560	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EHC68_24580	COG0745	RESPONSE REGULATOR receiver
EHC68_24595	COG1785	Belongs to the alkaline phosphatase family
EHC68_24615	COG0745	RESPONSE REGULATOR receiver
EHC68_24615	COG3706	GGDEF domain
EHC68_24625	COG0814	amino acid
EHC68_24635	COG0243	molybdopterin cofactor binding
EHC68_24640	COG1648	precorrin-2 dehydrogenase activity
EHC68_24640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EHC68_24660	COG3707	response regulator
EHC68_24670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EHC68_24675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EHC68_24680	COG1116	anion transmembrane transporter activity
EHC68_24685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC68_24685	COG2146	nitrite reductase [NAD(P)H] activity
EHC68_24740	COG0515	serine threonine protein kinase
EHC68_24740	COG2815	serine threonine protein kinase
EHC68_24780	COG0631	protein serine/threonine phosphatase activity
EHC68_24835	COG3501	Rhs element vgr protein
EHC68_24850	COG0420	3'-5' exonuclease activity
EHC68_24875	COG3040	lipid binding
EHC68_24885	COG2814	Major facilitator Superfamily
EHC68_24895	COG1288	antiporter activity
EHC68_24910	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EHC68_24925	COG2425	protein containing a von Willebrand factor type A (vWA) domain
EHC68_24945	COG0583	DNA-binding transcription factor activity
EHC68_24950	COG0277	FAD linked oxidase domain protein
EHC68_24970	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EHC68_25015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EHC68_25015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EHC68_25060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EHC68_25065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EHC68_25070	COG2146	nitrite reductase [NAD(P)H] activity
EHC68_25075	COG2116	formate transmembrane transporter activity
EHC68_25095	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EHC68_25130	COG0534	Mate efflux family protein
EHC68_25140	COG2814	Major facilitator Superfamily
EHC68_25145	COG3118	belongs to the thioredoxin family
EHC68_25150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EHC68_25175	COG2271	Major facilitator Superfamily
EHC68_25180	COG3851	Histidine kinase
EHC68_25185	COG2197	response regulator
EHC68_25200	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EHC68_25205	COG0583	DNA-binding transcription factor activity
EHC68_25215	COG0243	molybdopterin cofactor binding
EHC68_25245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EHC68_25260	COG1328	CTP reductase activity
EHC68_25265	COG0602	queuosine metabolic process
EHC68_25270	COG0534	Mate efflux family protein
EHC68_25290	COG0189	ligase activity
EHC68_25290	COG4067	protein conserved in archaea
EHC68_25300	COG3111	PFAM Bacterial OB fold (BOF) protein
EHC68_25305	COG1492	cobalamin metabolic process
EHC68_25310	COG0725	ABC transporter, periplasmic molybdate-binding protein
EHC68_25315	COG4149	molybdate abc transporter
EHC68_25320	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EHC68_25330	COG5001	Diguanylate cyclase
EHC68_25330	COG3706	GGDEF domain
EHC68_25330	COG4251	negative regulation of phosphorylation
EHC68_25330	COG2203	Gaf domain
EHC68_25340	COG0745	RESPONSE REGULATOR receiver
EHC68_25340	COG3706	GGDEF domain
EHC68_25355	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EHC68_25360	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EHC68_25385	COG3140	Belongs to the UPF0181 family
EHC68_25390	COG0589	response to stress
EHC68_25400	COG0583	DNA-binding transcription factor activity
EHC68_25420	COG0023	Translation Initiation Factor
EHC68_25430	COG1181	Belongs to the D-alanine--D-alanine ligase family
EHC68_25440	COG1042	CoA-binding domain protein
EHC68_25440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EHC68_25440	COG0045	succinate-CoA ligase (ADP-forming) activity
EHC68_25445	COG0583	DNA-binding transcription factor activity
EHC68_25450	COG1629	transport
EHC68_25450	COG4771	TonB-dependent receptor
EHC68_25460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EHC68_25465	COG5001	Diguanylate cyclase
EHC68_25465	COG5002	protein histidine kinase activity
EHC68_25465	COG3447	MASE1 domain protein
EHC68_25470	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EHC68_25475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EHC68_25480	COG1984	allophanate hydrolase subunit 2
EHC68_25490	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EHC68_25495	COG4181	ATPase activity
EHC68_25510	COG5001	Diguanylate cyclase
EHC68_25510	COG3300	MHYT domain
EHC68_25520	COG0484	heat shock protein binding
EHC68_25545	COG4533	DNA binding
EHC68_25555	COG2050	protein possibly involved in aromatic compounds catabolism
EHC68_25570	COG2067	long-chain fatty acid transport protein
EHC68_25575	COG2267	carboxylic ester hydrolase activity
EHC68_25590	COG0861	Integral membrane protein TerC family
EHC68_25595	COG0737	Belongs to the 5'-nucleotidase family
EHC68_25600	COG3593	DNA synthesis involved in DNA repair
EHC68_25610	COG0583	DNA-binding transcription factor activity
EHC68_25615	COG2116	formate transmembrane transporter activity
EHC68_25620	COG2353	YceI-like domain
EHC68_25625	COG3038	cytochrome b561
EHC68_25640	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EHC68_25645	COG0513	Belongs to the DEAD box helicase family
EHC68_25650	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
EHC68_25660	COG0840	transmembrane signaling receptor activity
EHC68_25670	COG0546	phosphoglycolate phosphatase activity
EHC68_25680	COG0784	Response regulator, receiver
EHC68_25680	COG3437	response regulator, receiver
EHC68_25700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EHC68_25705	COG2759	Belongs to the formate--tetrahydrofolate ligase family
EHC68_25710	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EHC68_25725	COG2207	Transcriptional regulator
EHC68_25730	COG1979	alcohol dehydrogenase
EHC68_25750	COG1840	ABC-type Fe3 transport system, periplasmic component
EHC68_25755	COG2271	Major facilitator Superfamily
EHC68_25760	COG0469	pyruvate kinase activity
EHC68_25765	COG1126	abc transporter atp-binding protein
EHC68_25770	COG0765	amino acid transport
EHC68_25775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EHC68_25780	COG0765	amino acid transport
EHC68_25785	COG2199	diguanylate cyclase activity
EHC68_25785	COG2200	EAL domain
EHC68_25785	COG2203	Gaf domain
EHC68_25805	COG1609	Transcriptional regulator
EHC68_25810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_25810	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EHC68_25815	COG1105	Belongs to the carbohydrate kinase PfkB family
EHC68_25820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_25820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EHC68_25820	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EHC68_25860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EHC68_25865	COG0509	glycine decarboxylation via glycine cleavage system
EHC68_25870	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC68_25870	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EHC68_25890	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EHC68_25895	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EHC68_25900	COG0583	DNA-binding transcription factor activity
EHC68_25905	COG2176	DNA-directed DNA polymerase activity
EHC68_25950	COG0242	peptide deformylase activity
EHC68_25970	COG2239	Acts as a magnesium transporter
EHC68_25990	COG0346	lactoylglutathione lyase activity
EHC68_25995	COG1902	pentaerythritol trinitrate reductase activity
EHC68_26020	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EHC68_26030	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EHC68_26030	COG0069	glutamate synthase activity
EHC68_26040	COG4565	transcriptional regulatory protein
EHC68_26045	COG3290	protein histidine kinase activity
EHC68_26050	COG0471	metal ion transport
EHC68_26080	COG2076	Multidrug Resistance protein
EHC68_26095	COG0671	phosphoesterase, PA-phosphatase related
EHC68_26110	COG2962	Rard protein
EHC68_26130	COG0835	chemotaxis
EHC68_26130	COG0784	Response regulator, receiver
EHC68_26155	COG2197	response regulator
EHC68_26165	COG3706	GGDEF domain
EHC68_26170	COG2197	response regulator
EHC68_26175	COG3300	MHYT domain
EHC68_26175	COG5001	Diguanylate cyclase
EHC68_26190	COG0583	DNA-binding transcription factor activity
EHC68_26195	COG0583	DNA-binding transcription factor activity
EHC68_26255	COG4964	Belongs to the GSP D family
EHC68_26280	COG2207	Transcriptional regulator
EHC68_26310	COG0582	viral genome integration into host DNA
EHC68_26340	COG0514	ATP-dependent DNA helicase (RecQ)
EHC68_26355	COG0737	Belongs to the 5'-nucleotidase family
EHC68_26360	COG1940	carbohydrate kinase activity
EHC68_26370	COG2814	Major facilitator Superfamily
EHC68_26370	COG0477	Major facilitator Superfamily
EHC68_26375	COG0457	Tetratricopeptide repeat
EHC68_26455	COG2801	Transposase and inactivated derivatives
EHC68_26530	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EHC68_26545	COG1943	Transposase
EHC68_26550	COG0840	transmembrane signaling receptor activity
EHC68_26565	COG1484	DNA-dependent DNA replication
EHC68_26605	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
EHC68_26970	COG0419	ATPase involved in DNA repair
EHC68_26995	COG1192	Involved in chromosome partitioning
EHC68_27020	COG5268	conjugation