locus-tag	class	description
IC830_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IC830_00030	COG0071	Belongs to the small heat shock protein (HSP20) family
IC830_00050	COG0752	glycyl-tRNA synthetase alpha subunit
IC830_00055	COG2119	membrane
IC830_00065	COG0425	Belongs to the sulfur carrier protein TusA family
IC830_00095	COG1739	Uncharacterized protein family UPF0029
IC830_00145	COG3335	DDE superfamily endonuclease
IC830_00160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IC830_00170	COG0352	thiamine-phosphate diphosphorylase activity
IC830_00175	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IC830_00180	COG2104	thiamine diphosphate biosynthetic process
IC830_00185	COG2022	thiamine diphosphate biosynthetic process
IC830_00225	COG3220	belongs to the UPF0276 family
IC830_00245	COG1280	lysine exporter protein (LysE YggA)
IC830_00280	COG0513	Belongs to the DEAD box helicase family
IC830_00305	COG0633	Ferredoxin
IC830_00360	COG1587	Uroporphyrinogen-III synthase
IC830_00365	COG0181	hydroxymethylbilane synthase activity
IC830_00375	COG1965	Belongs to the frataxin family
IC830_00385	COG0019	diaminopimelate decarboxylase activity
IC830_00400	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IC830_00415	COG3148	PFAM DTW domain containing protein
IC830_00435	COG2267	carboxylic ester hydrolase activity
IC830_00445	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
IC830_00450	COG0640	Transcriptional regulator
IC830_00455	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC830_00525	COG2884	Cell division ATP-binding protein ftsE
IC830_00540	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IC830_00545	COG0705	Rhomboid family
IC830_00550	COG1580	Controls the rotational direction of flagella during chemotaxis
IC830_00555	COG3161	chorismate lyase activity
IC830_00560	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IC830_00570	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IC830_00575	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IC830_00580	COG0534	Mate efflux family protein
IC830_00615	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IC830_00680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IC830_00725	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IC830_00735	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IC830_00745	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IC830_00750	COG0081	regulation of translation
IC830_00755	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IC830_00760	COG0222	ribosome binding
IC830_00795	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IC830_00800	COG1573	uracil-dna glycosylase
IC830_00835	COG0138	bifunctional purine biosynthesis protein purh
IC830_00860	COG1982	Orn Lys Arg decarboxylase major
IC830_00930	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IC830_00935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC830_00940	COG2264	protein methyltransferase activity
IC830_00950	COG0511	ligase activity, forming carbon-carbon bonds
IC830_00960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC830_00975	COG2814	Major facilitator Superfamily
IC830_01000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC830_01025	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
IC830_01030	COG1027	Aspartate ammonia-lyase
IC830_01035	COG3030	protein affecting phage T7 exclusion by the F plasmid
IC830_01040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IC830_01060	COG3678	ATP-independent chaperone mediated protein folding
IC830_01120	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IC830_01125	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
IC830_01130	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC830_01160	COG4942	peptidase
IC830_01165	COG1045	serine acetyltransferase
IC830_01175	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IC830_01180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IC830_01200	COG0471	metal ion transport
IC830_01205	COG0688	phosphatidylethanolamine metabolic process
IC830_01210	COG1162	GTPase activity
IC830_01215	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IC830_01285	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IC830_01290	COG0802	atpase or kinase
IC830_01315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IC830_01320	COG0330	HflC and HflK could
IC830_01330	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
IC830_01335	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC830_01350	COG1959	2 iron, 2 sulfur cluster binding
IC830_01355	COG0557	exoribonuclease II activity
IC830_01360	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC830_01365	COG0546	phosphoglycolate phosphatase activity
IC830_01390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IC830_01410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC830_01420	COG3089	Belongs to the UPF0270 family
IC830_01455	COG1047	Peptidyl-prolyl cis-trans
IC830_01460	COG1446	asparaginase
IC830_01465	COG2900	Belongs to the SlyX family
IC830_01475	COG0545	Peptidyl-prolyl cis-trans isomerase
IC830_01485	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IC830_01490	COG2923	Belongs to the DsrF TusC family
IC830_01505	COG0049	tRNA binding
IC830_01520	COG2906	2 iron, 2 sulfur cluster binding
IC830_01560	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IC830_01565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IC830_01570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IC830_01575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC830_01580	COG0137	argininosuccinate synthase activity
IC830_01595	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IC830_01595	COG0678	peroxiredoxin activity
IC830_01605	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
IC830_01635	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IC830_01640	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IC830_01655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IC830_01665	COG2965	DNA replication, synthesis of RNA primer
IC830_01675	COG0359	binds to the 23S rRNA
IC830_01690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC830_01700	COG0432	Pfam Uncharacterised protein family UPF0047
IC830_01715	COG0735	belongs to the Fur family
IC830_01745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IC830_01750	COG0175	sulfate reduction
IC830_01850	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IC830_01880	COG2199	diguanylate cyclase activity
IC830_01880	COG2200	EAL domain
IC830_01905	COG3267	Type II secretory pathway component ExeA
IC830_01905	COG3409	Peptidoglycan-binding domain 1 protein
IC830_01920	COG1459	type II secretion system
IC830_01965	COG1077	Cell shape determining protein MreB Mrl
IC830_01975	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IC830_01980	COG0424	maF-like protein
IC830_01995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC830_02000	COG0312	modulator of DNA gyrase
IC830_02010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
IC830_02020	COG0564	pseudouridine synthase activity
IC830_02030	COG3028	Belongs to the UPF0307 family
IC830_02035	COG0312	modulator of DNA gyrase
IC830_02045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IC830_02060	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IC830_02070	COG1137	ATPase activity
IC830_02085	COG0517	IMP dehydrogenase activity
IC830_02085	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IC830_02100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IC830_02120	COG5007	Belongs to the BolA IbaG family
IC830_02135	COG0251	oxidation-reduction process
IC830_02140	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
IC830_02145	COG0540	Belongs to the ATCase OTCase family
IC830_02155	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IC830_02160	COG2235	arginine
IC830_02190	COG2927	DNA polymerase III (CHI subunit)
IC830_02195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IC830_02200	COG0795	lipopolysaccharide-transporting ATPase activity
IC830_02205	COG0795	lipopolysaccharide-transporting ATPase activity
IC830_02250	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC830_02255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IC830_02260	COG1447	Phosphotransferase system cellobiose-specific component IIA
IC830_02270	COG3394	polysaccharide catabolic process
IC830_02280	COG3437	response regulator, receiver
IC830_02395	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IC830_02405	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IC830_02420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IC830_02440	COG0762	integral membrane protein
IC830_02445	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IC830_02450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IC830_02465	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IC830_02470	COG1678	Uncharacterized ACR, COG1678
IC830_02475	COG0189	ligase activity
IC830_02485	COG2356	endonuclease I
IC830_02500	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IC830_02520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC830_02540	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IC830_02580	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IC830_02585	COG3079	Belongs to the UPF0149 family
IC830_02615	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IC830_02625	COG1595	DNA-templated transcription, initiation
IC830_02630	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
IC830_02640	COG3086	response to oxidative stress
IC830_02645	COG0481	GTPase activity
IC830_02655	COG0571	ribonuclease III activity
IC830_02660	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IC830_02665	COG1381	Involved in DNA repair and RecF pathway recombination
IC830_02670	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IC830_02675	COG0736	holo-[acyl-carrier-protein] synthase activity
IC830_02700	COG0504	CTP synthase activity
IC830_02710	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IC830_02715	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
IC830_02725	COG0585	pseudouridine synthase activity
IC830_02730	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IC830_02735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IC830_02755	COG1546	Belongs to the CinA family
IC830_02765	COG2137	regulation of response to DNA damage stimulus
IC830_02835	COG3630	sodium ion export across plasma membrane
IC830_02845	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
IC830_02855	COG1238	metal cluster binding
IC830_02865	COG2918	glutathione biosynthetic process
IC830_02875	COG1854	S-ribosylhomocysteine lyase activity
IC830_02880	COG4536	flavin adenine dinucleotide binding
IC830_02895	COG0228	four-way junction DNA binding
IC830_02900	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IC830_02905	COG0336	Belongs to the RNA methyltransferase TrmD family
IC830_02910	COG0335	large ribosomal subunit rRNA binding
IC830_02920	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IC830_02925	COG0237	dephospho-CoA kinase activity
IC830_02935	COG1459	type II secretion system
IC830_02950	COG0157	Belongs to the NadC ModD family
IC830_03005	COG0842	Transport permease protein
IC830_03010	COG1560	Kdo2-lipid A biosynthetic process
IC830_03015	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IC830_03020	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
IC830_03025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC830_03035	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IC830_03070	COG3112	Uncharacterised protein family (UPF0231)
IC830_03080	COG0004	ammonium transporteR
IC830_03085	COG1840	ABC-type Fe3 transport system, periplasmic component
IC830_03095	COG3842	ATPase activity
IC830_03100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC830_03115	COG2971	BadF BadG BcrA BcrD
IC830_03135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC830_03155	COG2813	Specifically methylates the guanine in position
IC830_03160	COG0628	permease
IC830_03170	COG0316	Belongs to the HesB IscA family
IC830_03200	COG2027	D-alanyl-D-alanine carboxypeptidase
IC830_03205	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IC830_03215	COG1534	Rna-binding protein
IC830_03235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC830_03240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IC830_03255	COG0779	Required for maturation of 30S ribosomal subunits
IC830_03270	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IC830_03275	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IC830_03280	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IC830_03320	COG3154	lipid carrier protein
IC830_03325	COG3153	acetyltransferase
IC830_03355	COG0084	hydrolase, TatD family'
IC830_03360	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IC830_03365	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
IC830_03370	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
IC830_03380	COG0813	purine-nucleoside phosphorylase activity
IC830_03390	COG0560	Phosphoserine phosphatase
IC830_03410	COG0583	DNA-binding transcription factor activity
IC830_03515	COG0531	amino acid
IC830_03520	COG2731	YhcH YjgK YiaL family protein
IC830_03540	COG1085	galactose-1-phosphate uridylyltransferase
IC830_03545	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IC830_03550	COG2017	converts alpha-aldose to the beta-anomer
IC830_03565	COG2211	Major facilitator Superfamily
IC830_03570	COG1609	Transcriptional regulator
IC830_03575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC830_03615	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IC830_03620	COG2271	Major facilitator Superfamily
IC830_03625	COG0584	glycerophosphoryl diester phosphodiesterase
IC830_03630	COG2171	N-acyltransferase activity
IC830_03660	COG1074	ATP-dependent DNA helicase activity
IC830_03665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC830_03675	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IC830_03675	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IC830_03690	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IC830_03695	COG2166	iron-sulfur cluster assembly
IC830_03700	COG3706	GGDEF domain
IC830_03705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IC830_03710	COG0693	protein deglycase activity
IC830_03760	COG3056	Lipoprotein
IC830_03765	COG2813	Specifically methylates the guanine in position
IC830_03770	COG0271	Belongs to the BolA IbaG family
IC830_03775	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IC830_03790	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
IC830_03805	COG1477	protein flavinylation
IC830_03825	COG0514	ATP-dependent DNA helicase (RecQ)
IC830_03830	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC830_03845	COG0733	neurotransmitter:sodium symporter activity
IC830_03870	COG1720	tRNA m6t6A37 methyltransferase activity
IC830_03875	COG0254	rRNA binding
IC830_03885	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IC830_03915	COG3098	single-species biofilm formation
IC830_03920	COG0564	pseudouridine synthase activity
IC830_03935	COG0024	Methionine aminopeptidase
IC830_03955	COG0233	cytoplasmic translational termination
IC830_03960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IC830_03965	COG0575	Belongs to the CDS family
IC830_03970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
IC830_03975	COG0750	zinc metalloprotease
IC830_03985	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
IC830_03990	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC830_04005	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC830_04010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IC830_04035	COG0347	Belongs to the P(II) protein family
IC830_04040	COG3021	interspecies interaction between organisms
IC830_04050	COG1388	LysM domain
IC830_04050	COG0741	lytic transglycosylase activity
IC830_04065	COG0328	RNA-DNA hybrid ribonuclease activity
IC830_04070	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC830_04090	COG0456	acetyltransferase
IC830_04100	COG1960	acyl-CoA dehydrogenase activity
IC830_04105	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IC830_04110	COG0121	glutamine amidotransferase
IC830_04125	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IC830_04130	COG2233	PERMEase
IC830_04155	COG4783	chaperone-mediated protein folding
IC830_04170	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IC830_04180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IC830_04185	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IC830_04200	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IC830_04205	COG1393	Belongs to the ArsC family
IC830_04230	COG2837	iron assimilation
IC830_04235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IC830_04240	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IC830_04250	COG1334	flagellar protein FlaG
IC830_04265	COG1516	flagellar protein fliS
IC830_04285	COG1677	Flagellar hook-basal body complex protein FliE
IC830_04345	COG1987	bacterial-type flagellum assembly
IC830_04350	COG1684	flagellar biosynthetic protein fliR
IC830_04390	COG2198	Histidine kinase
IC830_04390	COG0784	Response regulator, receiver
IC830_04390	COG0643	Histidine kinase
IC830_04400	COG1192	Involved in chromosome partitioning
IC830_04410	COG0835	chemotaxis
IC830_04425	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IC830_04430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IC830_04435	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IC830_04440	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
IC830_04445	COG1138	Cytochrome C-type biogenesis protein
IC830_04450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
IC830_04465	COG2853	Lipoprotein
IC830_04490	COG0183	Belongs to the thiolase family
IC830_04510	COG2062	phosphohistidine phosphatase, SixA
IC830_04515	COG2840	Smr protein MutS2
IC830_04530	COG2860	membrane
IC830_04535	COG3101	peptidyl-lysine hydroxylation
IC830_04545	COG0431	NADPH-dependent FMN reductase
IC830_04550	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IC830_04550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IC830_04575	COG0101	tRNA pseudouridine synthase activity
IC830_04580	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IC830_04585	COG0285	dihydrofolate synthase activity
IC830_04590	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
IC830_04600	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IC830_04610	COG0745	RESPONSE REGULATOR receiver
IC830_04615	COG2832	Protein of unknown function (DUF454)
IC830_04620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IC830_04630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IC830_04635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IC830_04640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IC830_04650	COG0251	oxidation-reduction process
IC830_04670	COG2261	transglycosylase associated protein
IC830_04675	COG2983	Belongs to the UPF0260 family
IC830_04680	COG0668	transmembrane transport
IC830_04685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IC830_04700	COG1785	Belongs to the alkaline phosphatase family
IC830_04715	COG2226	methyltransferase
IC830_04730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IC830_04745	COG3139	Protein of unknown function (DUF1315)
IC830_04765	COG0778	Nitroreductase
IC830_04800	COG3082	Protein of unknown function (DUF1414)
IC830_04820	COG1757	Na H antiporter
IC830_04835	COG2095	MarC family integral membrane protein
IC830_04840	COG1012	belongs to the aldehyde dehydrogenase family
IC830_04840	COG1454	alcohol dehydrogenase
IC830_04875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IC830_04890	COG0346	lactoylglutathione lyase activity
IC830_04900	COG4660	Part of a membrane complex involved in electron transport
IC830_04905	COG4659	FMN binding
IC830_04920	COG2878	Part of a membrane complex involved in electron transport
IC830_04925	COG4657	Part of a membrane complex involved in electron transport
IC830_04940	COG2204	response regulator
IC830_04945	COG2198	Histidine kinase
IC830_04950	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IC830_04955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IC830_04965	COG0315	cyclic pyranopterin monophosphate synthase activity
IC830_04975	COG0314	molybdopterin synthase activity
IC830_04995	COG0444	Belongs to the ABC transporter superfamily
IC830_05005	COG0435	Glutathione S-transferase
IC830_05015	COG3174	membrane
IC830_05025	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC830_05040	COG4120	Belongs to the binding-protein-dependent transport system permease family
IC830_05050	COG0366	Alpha amylase catalytic
IC830_05060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IC830_05065	COG0653	protein targeting
IC830_05075	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IC830_05100	COG0572	uridine kinase
IC830_05110	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IC830_05115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IC830_05130	COG0564	pseudouridine synthase activity
IC830_05135	COG0424	maF-like protein
IC830_05140	COG1399	metal-binding, possibly nucleic acid-binding protein
IC830_05150	COG0416	fatty acid biosynthetic process
IC830_05190	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IC830_05200	COG0084	hydrolase, TatD family'
IC830_05220	COG0733	neurotransmitter:sodium symporter activity
IC830_05235	COG4667	esterase of the alpha-beta hydrolase superfamily
IC830_05245	COG1940	carbohydrate kinase activity
IC830_05250	COG0784	Response regulator, receiver
IC830_05250	COG0835	chemotaxis
IC830_05280	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IC830_05335	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IC830_05350	COG2995	paraquat-inducible protein a
IC830_05355	COG3258	Cytochrome c
IC830_05360	COG2863	cytochrome
IC830_05405	COG3118	belongs to the thioredoxin family
IC830_05445	COG1136	(ABC) transporter
IC830_05445	COG0577	efflux transmembrane transporter activity
IC830_05450	COG0577	efflux transmembrane transporter activity
IC830_05450	COG1136	(ABC) transporter
IC830_05460	COG1335	isochorismatase
IC830_05510	COG5002	protein histidine kinase activity
IC830_05510	COG3850	Histidine kinase
IC830_05515	COG0745	RESPONSE REGULATOR receiver
IC830_05520	COG0840	transmembrane signaling receptor activity
IC830_05545	COG0583	DNA-binding transcription factor activity
IC830_05560	COG2350	Protein conserved in bacteria
IC830_05570	COG2917	probably involved in intracellular septation
IC830_05610	COG0133	tryptophan synthase activity
IC830_05620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IC830_05625	COG0512	Glutamine amidotransferase of anthranilate synthase
IC830_05630	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IC830_05645	COG0009	L-threonylcarbamoyladenylate synthase
IC830_05665	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IC830_05680	COG2197	response regulator
IC830_05685	COG0322	excinuclease ABC activity
IC830_05725	COG0019	diaminopimelate decarboxylase activity
IC830_05750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IC830_05790	COG0437	4 iron, 4 sulfur cluster binding
IC830_05795	COG3301	Polysulphide reductase, NrfD
IC830_05810	COG3088	subunit of a heme lyase
IC830_05810	COG4235	cytochrome complex assembly
IC830_05820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC830_05845	COG2989	Protein conserved in bacteria
IC830_05855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IC830_05870	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IC830_05895	COG1846	Transcriptional regulator
IC830_05940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC830_05950	COG0017	Asparaginyl-tRNA synthetase
IC830_05960	COG0720	synthase
IC830_05975	COG1760	l-serine dehydratase
IC830_05985	COG0494	nUDIX hydrolase
IC830_06195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IC830_06585	COG0346	lactoylglutathione lyase activity
IC830_06705	COG1403	HNH endonuclease
IC830_06915	COG0456	acetyltransferase
IC830_06915	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IC830_06945	COG1280	lysine exporter protein (LysE YggA)
IC830_06950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC830_06975	COG0174	glutamine synthetase
IC830_06980	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IC830_06985	COG1396	sequence-specific DNA binding
IC830_06985	COG1917	Cupin 2, conserved barrel domain protein
IC830_06990	COG1012	belongs to the aldehyde dehydrogenase family
IC830_06995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IC830_07005	COG2957	Belongs to the agmatine deiminase family
IC830_07035	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IC830_07055	COG2315	Protein conserved in bacteria
IC830_07105	COG3063	Type IV pilus biogenesis stability protein PilW
IC830_07110	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IC830_07125	COG1560	Kdo2-lipid A biosynthetic process
IC830_07135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IC830_07230	COG1280	lysine exporter protein (LysE YggA)
IC830_07265	COG1368	sulfuric ester hydrolase activity
IC830_07275	COG0745	RESPONSE REGULATOR receiver
IC830_07285	COG1028	Short-chain dehydrogenase reductase Sdr
IC830_07310	COG4176	ABC-type proline glycine betaine transport system permease component
IC830_07345	COG0662	Cupin 2, conserved barrel domain protein
IC830_07350	COG0527	aspartate kinase activity
IC830_07405	COG4565	transcriptional regulatory protein
IC830_07410	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IC830_07415	COG0363	glucosamine-6-phosphate deaminase activity
IC830_07420	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IC830_07450	COG1012	belongs to the aldehyde dehydrogenase family
IC830_07540	COG3177	Filamentation induced by cAMP protein fic
IC830_07570	COG1073	alpha beta
IC830_07590	COG4791	protein targeting
IC830_07595	COG4794	Type iii secretion
IC830_07600	COG4790	Type iii secretion
IC830_07690	COG0730	response to heat
IC830_07725	COG0372	Belongs to the citrate synthase family
IC830_07765	COG0602	queuosine metabolic process
IC830_07770	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IC830_07775	COG3706	GGDEF domain
IC830_07820	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IC830_07830	COG1254	Belongs to the acylphosphatase family
IC830_07835	COG2920	part of a sulfur-relay system
IC830_07845	COG0670	Belongs to the BI1 family
IC830_07850	COG1126	abc transporter atp-binding protein
IC830_07875	COG1666	GTP binding
IC830_07900	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IC830_07900	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
IC830_07905	COG3008	intermembrane lipid transfer
IC830_07910	COG2995	paraquat-inducible protein a
IC830_07920	COG1956	GAF domain-containing protein
IC830_07925	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
IC830_07990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IC830_07995	COG1067	ATP-dependent peptidase activity
IC830_08000	COG3120	sequence-specific DNA binding
IC830_08105	COG3278	Belongs to the heme-copper respiratory oxidase family
IC830_08120	COG2010	Cytochrome c
IC830_08145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IC830_08185	COG1177	transmembrane transport
IC830_08200	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IC830_08210	COG0004	ammonium transporteR
IC830_08240	COG0437	4 iron, 4 sulfur cluster binding
IC830_08255	COG3381	protein complex oligomerization
IC830_08305	COG3842	ATPase activity
IC830_08325	COG1940	carbohydrate kinase activity
IC830_08370	COG0791	NLP P60 protein
IC830_08380	COG3706	GGDEF domain
IC830_08385	COG2201	protein-glutamate methylesterase activity
IC830_08400	COG0307	riboflavin synthase, alpha
IC830_08415	COG1793	dna ligase
IC830_08490	COG1215	transferase activity, transferring glycosyl groups
IC830_08495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC830_08530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC830_08530	COG2221	Nitrite and sulphite reductase 4Fe-4S
IC830_08535	COG3381	protein complex oligomerization
IC830_08540	COG3302	dmso reductase anchor subunit
IC830_08545	COG0437	4 iron, 4 sulfur cluster binding
IC830_08620	COG1132	(ABC) transporter
IC830_08625	COG1132	(ABC) transporter
IC830_08655	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
IC830_08725	COG1522	sequence-specific DNA binding
IC830_08760	COG0515	serine threonine protein kinase
IC830_08785	COG3501	Rhs element vgr protein
IC830_08835	COG0739	heme binding
IC830_08850	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IC830_08880	COG4191	Histidine kinase
IC830_08880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC830_08885	COG0471	metal ion transport
IC830_08920	COG0583	DNA-binding transcription factor activity
IC830_08985	COG0625	glutathione transferase activity
IC830_09020	COG0601	transmembrane transport
IC830_09055	COG1177	transmembrane transport
IC830_09060	COG1176	ABC-type spermidine putrescine transport system, permease component I
IC830_09090	COG3938	Belongs to the proline racemase family
IC830_09120	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
IC830_09125	COG1451	nucleotide metabolic process
IC830_09135	COG0583	DNA-binding transcription factor activity
IC830_09190	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IC830_09200	COG1823	symporter activity
IC830_09205	COG2925	Exonuclease
IC830_09215	COG1346	cytolysis
IC830_09225	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IC830_09240	COG0776	regulation of translation
IC830_09300	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IC830_09335	COG0010	Belongs to the arginase family
IC830_09340	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
IC830_09415	COG1643	Atp-dependent helicase
IC830_09420	COG0281	malic enzyme
IC830_09425	COG2949	membrane
IC830_09545	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IC830_09580	COG0534	Mate efflux family protein
IC830_09590	COG3005	denitrification pathway
IC830_09630	COG1061	Type III restriction enzyme res subunit
IC830_09650	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IC830_09675	COG3313	Fe-S protein
IC830_09715	COG4134	Bacterial extracellular solute-binding protein
IC830_09720	COG4135	transport system, permease component
IC830_09730	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IC830_09740	COG3604	Transcriptional regulator
IC830_09745	COG1151	hydroxylamine reductase activity
IC830_09760	COG0564	pseudouridine synthase activity
IC830_09785	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
IC830_09790	COG5380	lipid catabolic process
IC830_09795	COG2818	Glycosylase
IC830_09815	COG1983	PspC domain protein
IC830_09825	COG1842	Phage shock protein A
IC830_09845	COG4171	peptide transport system, permease
IC830_09880	COG0243	molybdopterin cofactor binding
IC830_09885	COG3005	denitrification pathway
IC830_09890	COG4459	periplasmic nitrate reductase
IC830_09895	COG0390	transport system, permease component
IC830_09945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC830_09950	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IC830_09960	COG3012	SEC-C Motif Domain Protein
IC830_09970	COG0107	imidazoleglycerol-phosphate synthase activity
IC830_09975	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IC830_09980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IC830_09985	COG0131	Imidazoleglycerol-phosphate dehydratase
IC830_09985	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IC830_09990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IC830_09995	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IC830_10040	COG2915	High frequency lysogenization protein hflD homolog
IC830_10045	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IC830_10080	COG0300	oxidoreductase activity
IC830_10120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IC830_10125	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IC830_10140	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IC830_10145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IC830_10185	COG0583	DNA-binding transcription factor activity
IC830_10265	COG0754	glutathionylspermidine amidase activity
IC830_10275	COG3766	membrane
IC830_10315	COG0811	peptide transport
IC830_10320	COG0824	Thioesterase
IC830_10330	COG4890	Cyd operon protein YbgT
IC830_10335	COG1294	oxidase, subunit
IC830_10340	COG1271	oxidase subunit
IC830_10360	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IC830_10365	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IC830_10370	COG1801	Protein of unknown function DUF72
IC830_10375	COG4106	trans-aconitate 2-methyltransferase activity
IC830_10380	COG0500	methyltransferase
IC830_10410	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
IC830_10420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC830_10425	COG1434	Gram-negative-bacterium-type cell wall biogenesis
IC830_10430	COG0745	RESPONSE REGULATOR receiver
IC830_10435	COG3381	protein complex oligomerization
IC830_10495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IC830_10505	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IC830_10520	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IC830_10525	COG1278	Cold shock
IC830_10555	COG0730	response to heat
IC830_10560	COG3923	Primosomal replication protein n
IC830_10570	COG0708	Exodeoxyribonuclease III
IC830_10630	COG3013	Belongs to the UPF0304 family
IC830_10645	COG2719	SpoVR family
IC830_10650	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IC830_10670	COG2333	competence protein COMEC
IC830_10670	COG0658	competence protein
IC830_10690	COG4591	ABC-type transport system involved in lipoprotein release permease component
IC830_10720	COG3150	esterase
IC830_10745	COG0537	adenosine 5'-monophosphoramidase activity
IC830_10770	COG0516	GMP reductase activity
IC830_10770	COG0517	IMP dehydrogenase activity
IC830_10775	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
IC830_10780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IC830_10785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC830_10815	COG1946	Acyl-CoA thioesterase
IC830_10825	COG1522	sequence-specific DNA binding
IC830_10930	COG0596	Alpha beta hydrolase
IC830_10945	COG0436	Aminotransferase
IC830_10970	COG1555	photosystem II stabilization
IC830_10980	COG0776	regulation of translation
IC830_11000	COG0544	peptidyl-prolyl cis-trans isomerase activity
IC830_11025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IC830_11030	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IC830_11055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC830_11060	COG0569	domain protein
IC830_11065	COG0513	Belongs to the DEAD box helicase family
IC830_11070	COG1253	flavin adenine dinucleotide binding
IC830_11105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC830_11110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IC830_11125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IC830_11130	COG1216	Glycosyl transferase, family 2
IC830_11170	COG1028	Short-chain dehydrogenase reductase Sdr
IC830_11305	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IC830_11335	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IC830_11340	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IC830_11345	COG0583	DNA-binding transcription factor activity
IC830_11350	COG2951	lytic endotransglycosylase activity
IC830_11365	COG2894	cell division
IC830_11370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IC830_11385	COG2267	carboxylic ester hydrolase activity
IC830_11410	COG0788	formyltetrahydrofolate deformylase activity
IC830_11415	COG3102	Protein conserved in bacteria
IC830_11440	COG1918	ferrous iron import across plasma membrane
IC830_11450	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
IC830_11455	COG1121	(ABC) transporter
IC830_11460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC830_11475	COG0508	dehydrogenase complex catalyzes the overall conversion of
IC830_11485	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IC830_11495	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IC830_11510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IC830_11530	COG0596	Alpha beta hydrolase
IC830_11550	COG0735	belongs to the Fur family
IC830_11570	COG1940	carbohydrate kinase activity
IC830_11570	COG1846	Transcriptional regulator
IC830_11585	COG0250	Participates in transcription elongation, termination and antitermination
IC830_11600	COG0563	adenylate kinase activity
IC830_11630	COG0622	Phosphoesterase
IC830_11655	COG1090	epimerase
IC830_11695	COG3115	cell septum assembly
IC830_11700	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
IC830_11705	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IC830_11715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IC830_11720	COG2190	(PTS) system
IC830_11735	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IC830_11740	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IC830_11755	COG1705	Flagellar rod assembly protein muramidase FlgJ
IC830_11755	COG3951	Flagellar rod assembly protein muramidase FlgJ
IC830_11760	COG1706	bacterial-type flagellum-dependent cell motility
IC830_11780	COG1749	Flagellar hook protein flgE
IC830_11790	COG1558	bacterial-type flagellum-dependent cell motility
IC830_11795	COG1815	bacterial-type flagellum-dependent cell motility
IC830_11800	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
IC830_11805	COG0784	Response regulator, receiver
IC830_11805	COG0835	chemotaxis
IC830_11905	COG2840	Smr protein MutS2
IC830_11910	COG1187	pseudouridine synthase activity
IC830_11925	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IC830_11935	COG3094	Invasion gene expression up-regulator, SirB
IC830_11940	COG2890	protein-(glutamine-N5) methyltransferase activity
IC830_11945	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IC830_11955	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IC830_11960	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IC830_11965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IC830_11975	COG0012	GTP binding
IC830_12100	COG1702	phosphate starvation-inducible protein PhoH
IC830_12105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IC830_12110	COG4535	Mg2 and Co2 transporter CorC
IC830_12115	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IC830_12120	COG2888	peptidyl-tyrosine sulfation
IC830_12130	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
IC830_12135	COG1466	dna polymerase III delta subunit
IC830_12140	COG0799	negative regulation of ribosome biogenesis
IC830_12145	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IC830_12155	COG0772	Belongs to the SEDS family
IC830_12175	COG0321	lipoyl(octanoyl) transferase activity
IC830_12230	COG2011	ABC-type metal ion transport system permease component
IC830_12235	COG1464	Belongs to the NlpA lipoprotein family
IC830_12240	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
IC830_12250	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IC830_12250	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
IC830_12270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IC830_12280	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
IC830_12285	COG2363	Small membrane protein
IC830_12300	COG0301	tRNA thio-modification
IC830_12300	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IC830_12315	COG1722	exodeoxyribonuclease VII activity
IC830_12320	COG0142	geranyltranstransferase activity
IC830_12330	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IC830_12335	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IC830_12365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IC830_12375	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IC830_12400	COG2195	Cleaves the N-terminal amino acid of tripeptides
IC830_12430	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
IC830_12470	COG0484	heat shock protein binding
IC830_12490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IC830_12505	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IC830_12510	COG2914	Belongs to the UPF0125 (RnfH) family
IC830_12520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IC830_12540	COG0583	DNA-binding transcription factor activity
IC830_12565	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
IC830_12600	COG1115	amino acid carrier protein
IC830_12620	COG1757	Na H antiporter
IC830_12625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IC830_12625	COG0519	Catalyzes the synthesis of GMP from XMP
IC830_12660	COG2976	Protein conserved in bacteria
IC830_12670	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
IC830_12695	COG2975	iron-sulfur cluster assembly
IC830_12710	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IC830_12725	COG1104	cysteine desulfurase activity
IC830_12740	COG0483	inositol monophosphate 1-phosphatase activity
IC830_12745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC830_12750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC830_12755	COG1862	Preprotein translocase
IC830_12765	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IC830_12775	COG0517	IMP dehydrogenase activity
IC830_12795	COG0450	alkyl hydroperoxide reductase
IC830_12800	COG3142	Participates in the control of copper homeostasis
IC830_12810	COG0704	Plays a role in the regulation of phosphate uptake
IC830_12815	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IC830_12845	COG5002	protein histidine kinase activity
IC830_12850	COG0745	RESPONSE REGULATOR receiver
IC830_12865	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IC830_12930	COG0564	pseudouridine synthase activity
IC830_12950	COG1605	Chorismate mutase
IC830_12950	COG0077	Prephenate dehydratase
IC830_12955	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
IC830_12960	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
IC830_12980	COG0739	heme binding
IC830_12990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IC830_12995	COG1472	Belongs to the glycosyl hydrolase 3 family
IC830_13000	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IC830_13005	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IC830_13020	COG1966	Carbon starvation protein
IC830_13030	COG3279	Response regulator of the LytR AlgR family
IC830_13035	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IC830_13040	COG1047	Peptidyl-prolyl cis-trans
IC830_13045	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IC830_13060	COG0728	peptidoglycan biosynthetic process
IC830_13065	COG0268	Binds directly to 16S ribosomal RNA
IC830_13070	COG0640	Transcriptional regulator
IC830_13080	COG1283	sodium-dependent phosphate transmembrane transporter activity
IC830_13090	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IC830_13095	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IC830_13100	COG0730	response to heat
IC830_13110	COG0494	nUDIX hydrolase
IC830_13125	COG0667	Aldo Keto reductase
IC830_13140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IC830_13165	COG0716	FMN binding
IC830_13175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IC830_13180	COG0513	Belongs to the DEAD box helicase family
IC830_13185	COG3022	response to hydroperoxide
IC830_13190	COG1115	amino acid carrier protein
IC830_13205	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IC830_13215	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
IC830_13220	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IC830_13300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IC830_13310	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IC830_13315	COG2860	membrane
IC830_13320	COG0583	DNA-binding transcription factor activity
IC830_13325	COG0730	response to heat
IC830_13345	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IC830_13350	COG0494	nUDIX hydrolase
IC830_13365	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IC830_13395	COG0772	Belongs to the SEDS family
IC830_13400	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IC830_13415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IC830_13420	COG0768	penicillin binding
IC830_13425	COG3116	cell division
IC830_13440	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IC830_13450	COG0792	nuclease activity
IC830_13455	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IC830_13460	COG2823	Periplasmic or secreted lipoprotein
IC830_13465	COG2969	positive regulation of protein catabolic process
IC830_13470	COG0625	glutathione transferase activity
IC830_13490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IC830_13495	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IC830_13530	COG3150	esterase
IC830_13540	COG3151	Protein conserved in bacteria
IC830_13545	COG0494	nUDIX hydrolase
IC830_13555	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IC830_13555	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IC830_13590	COG4991	sh3 domain protein
IC830_13600	COG3409	Peptidoglycan-binding domain 1 protein
IC830_13600	COG3267	Type II secretory pathway component ExeA
IC830_13610	COG1968	undecaprenyl-diphosphatase activity
IC830_13615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IC830_13620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IC830_13625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IC830_13640	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IC830_13645	COG1610	YqeY-like protein
IC830_13650	COG0358	DNA primase activity
IC830_13700	COG0246	Mannitol dehydrogenase
IC830_13720	COG1461	Dihydroxyacetone kinase
IC830_13735	COG5002	protein histidine kinase activity
IC830_13750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IC830_13760	COG0469	pyruvate kinase activity
IC830_13775	COG0440	acetolactate synthase activity
IC830_13860	COG2967	ApaG domain
IC830_13880	COG2966	Psort location CytoplasmicMembrane, score
IC830_13895	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IC830_13935	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
IC830_13940	COG1178	ABC-type Fe3 transport system permease component
IC830_13955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IC830_13960	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IC830_13965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IC830_13975	COG2105	PFAM AIG2 family protein
IC830_13980	COG2911	Protein conserved in bacteria
IC830_14000	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
IC830_14015	COG1136	(ABC) transporter
IC830_14035	COG0529	Catalyzes the synthesis of activated sulfate
IC830_14045	COG2895	sulfate adenylyltransferase (ATP) activity
IC830_14055	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC830_14055	COG1648	precorrin-2 dehydrogenase activity
IC830_14075	COG2153	protein acetylation
IC830_14085	COG0545	Peptidyl-prolyl cis-trans isomerase
IC830_14095	COG0203	ribosomal protein L17
IC830_14110	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IC830_14115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IC830_14125	COG0201	protein transport
IC830_14130	COG0200	Binds to the 23S rRNA
IC830_14135	COG1841	ribosomal large subunit assembly
IC830_14150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IC830_14155	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IC830_14160	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IC830_14165	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IC830_14170	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IC830_14180	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IC830_14185	COG0255	Belongs to the universal ribosomal protein uL29 family
IC830_14200	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IC830_14205	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IC830_14210	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IC830_14225	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IC830_14235	COG0254	rRNA binding
IC830_14255	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IC830_14260	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IC830_14275	COG3074	FtsZ-dependent cytokinesis
IC830_14305	COG0149	triose-phosphate isomerase activity
IC830_14325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IC830_14340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IC830_14375	COG0728	peptidoglycan biosynthetic process
IC830_14395	COG3206	protein involved in exopolysaccharide biosynthesis
IC830_14395	COG0489	protein tyrosine kinase activity
IC830_14395	COG3206	protein involved in exopolysaccharide biosynthesis
IC830_14395	COG0489	protein tyrosine kinase activity
IC830_14435	COG1560	Kdo2-lipid A biosynthetic process
IC830_14440	COG0859	PFAM glycosyl transferase family 9
IC830_14445	COG1519	Transferase
IC830_14455	COG1083	cytidylyl-transferase
IC830_14460	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IC830_14475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IC830_14480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IC830_14515	COG3642	lipopolysaccharide core region biosynthetic process
IC830_14520	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IC830_14530	COG0463	Glycosyl transferase, family 2
IC830_14555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IC830_14570	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IC830_14580	COG0840	transmembrane signaling receptor activity
IC830_14585	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IC830_14590	COG1309	transcriptional regulator
IC830_14605	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IC830_14625	COG0444	Belongs to the ABC transporter superfamily
IC830_14635	COG4239	(ABC) transporter, permease
IC830_14665	COG0848	biopolymer transport protein
IC830_14680	COG0194	GDP metabolic process
IC830_14685	COG1758	RNA polymerase activity
IC830_14695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IC830_14725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC830_14745	COG0596	Alpha beta hydrolase
IC830_14750	COG1040	competence protein
IC830_14755	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
IC830_14755	COG0316	Belongs to the HesB IscA family
IC830_14775	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IC830_14780	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
IC830_14785	COG3156	type II secretion system protein K
IC830_14795	COG2165	general secretion pathway protein
IC830_14800	COG2165	general secretion pathway protein
IC830_14810	COG1459	type II secretion system
IC830_14830	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IC830_14835	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IC830_14850	COG0456	acetyltransferase
IC830_14855	COG1490	D-aminoacyl-tRNA deacylase activity
IC830_14860	COG1295	ribonuclease BN
IC830_14890	COG3852	Histidine kinase
IC830_14960	COG0084	hydrolase, TatD family'
IC830_14965	COG0805	protein transport
IC830_14970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC830_14975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IC830_14980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IC830_14985	COG3165	ubiquinone biosynthetic process from chorismate
IC830_14990	COG2226	methyltransferase
IC830_14995	COG1322	Protein conserved in bacteria
IC830_15010	COG0628	permease
IC830_15040	COG1597	lipid kinase activity
IC830_15060	COG2823	Periplasmic or secreted lipoprotein
IC830_15085	COG0589	response to stress
IC830_15120	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IC830_15125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IC830_15130	COG0583	DNA-binding transcription factor activity
IC830_15140	COG0800	Aldolase
IC830_15150	COG3265	gluconokinase activity
IC830_15170	COG0583	DNA-binding transcription factor activity
IC830_15175	COG1609	Transcriptional regulator
IC830_15210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IC830_15215	COG0601	transmembrane transport
IC830_15225	COG4172	Belongs to the ABC transporter superfamily
IC830_15285	COG2960	long-chain fatty acid transporting porin activity
IC830_15330	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IC830_15350	COG0009	L-threonylcarbamoyladenylate synthase
IC830_15355	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IC830_15360	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IC830_15365	COG0551	DNA topoisomerase type I activity
IC830_15370	COG2922	Belongs to the Smg family
IC830_15375	COG0758	DNA mediated transformation
IC830_15385	COG0242	peptide deformylase activity
IC830_15390	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IC830_15400	COG0569	domain protein
IC830_15405	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC830_15415	COG1272	protein, Hemolysin III
IC830_15425	COG3084	Protein conserved in bacteria
IC830_15435	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IC830_15465	COG3978	acetolactate synthase activity
IC830_15470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IC830_15485	COG0583	DNA-binding transcription factor activity
IC830_15490	COG2814	Major facilitator Superfamily
IC830_15505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IC830_15530	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IC830_15555	COG1475	DNA binding
IC830_15560	COG1192	Involved in chromosome partitioning
IC830_15565	COG0357	Ribosomal RNA small subunit methyltransferase G
IC830_15575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IC830_15585	COG0706	membrane insertase activity
IC830_15595	COG0594	ribonuclease P activity
IC830_15655	COG2239	Acts as a magnesium transporter
IC830_15660	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IC830_15665	COG0402	S-adenosylhomocysteine deaminase activity
IC830_15695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC830_15730	COG4221	oxidoreductase activity
IC830_15735	COG0745	RESPONSE REGULATOR receiver
IC830_15750	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
IC830_15760	COG0673	inositol 2-dehydrogenase activity
IC830_15795	COG4667	esterase of the alpha-beta hydrolase superfamily
IC830_15800	COG1741	Belongs to the pirin family
IC830_15805	COG1278	Cold shock
IC830_15845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IC830_15875	COG1028	Short-chain dehydrogenase reductase Sdr
IC830_15985	COG3097	Belongs to the UPF0267 family
IC830_15990	COG1309	transcriptional regulator
IC830_16020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC830_16050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC830_16065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IC830_16070	COG0569	domain protein
IC830_16085	COG1132	(ABC) transporter
IC830_16095	COG1120	ATPase activity
IC830_16100	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
IC830_16165	COG0714	Associated with various cellular activities
IC830_16210	COG0581	inorganic phosphate transmembrane transporter activity
IC830_16215	COG0573	inorganic phosphate transmembrane transporter activity
IC830_16255	COG0513	Belongs to the DEAD box helicase family
IC830_16265	COG1388	LysM domain
IC830_16265	COG1376	ErfK ybiS ycfS ynhG family protein
IC830_16275	COG0789	Transcriptional regulator
IC830_16285	COG0813	purine-nucleoside phosphorylase activity
IC830_16310	COG1566	PFAM secretion protein HlyD family protein
IC830_16315	COG4720	Psort location CytoplasmicMembrane, score
IC830_16335	COG0348	domain, Protein
IC830_16340	COG0437	4 iron, 4 sulfur cluster binding
IC830_16390	COG0583	DNA-binding transcription factor activity
IC830_16395	COG1620	l-lactate permease
IC830_16400	COG1304	FMN binding
IC830_16445	COG1063	alcohol dehydrogenase
IC830_16460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC830_16505	COG0346	lactoylglutathione lyase activity
IC830_16605	COG1987	bacterial-type flagellum assembly
IC830_16615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
IC830_16650	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
IC830_16655	COG1516	flagellar protein fliS
IC830_16675	COG1191	sigma factor activity
IC830_16735	COG0454	-acetyltransferase
IC830_16790	COG0628	permease
IC830_16795	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IC830_16805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IC830_16815	COG4628	conserved protein (DUF2132)
IC830_16845	COG1686	Belongs to the peptidase S11 family
IC830_16865	COG3397	chitin binding
IC830_16870	COG4667	esterase of the alpha-beta hydrolase superfamily
IC830_16875	COG2095	MarC family integral membrane protein
IC830_16925	COG3339	Conserved Protein
IC830_16930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IC830_16940	COG3366	ferrous iron transmembrane transporter activity
IC830_16995	COG1999	signal sequence binding
IC830_17005	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IC830_17005	COG1263	PTS System
IC830_17010	COG1162	GTPase activity
IC830_17025	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
IC830_17035	COG0531	amino acid
IC830_17040	COG1982	Orn Lys Arg decarboxylase major
IC830_17060	COG2356	endonuclease I
IC830_17095	COG2814	Major facilitator Superfamily
IC830_17125	COG1120	ATPase activity
IC830_17130	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC830_17175	COG0019	diaminopimelate decarboxylase activity
IC830_17225	COG0463	Glycosyl transferase, family 2
IC830_17245	COG1764	response to oxidative stress
IC830_17250	COG1846	Transcriptional regulator
IC830_17260	COG3634	alkyl hydroperoxide reductase activity
IC830_17285	COG1595	DNA-templated transcription, initiation
IC830_17345	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IC830_17355	COG0246	Mannitol dehydrogenase
IC830_17365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC830_17370	COG0800	Aldolase
IC830_17390	COG2207	Transcriptional regulator
IC830_17445	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IC830_17530	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IC830_17545	COG3340	Belongs to the peptidase S51 family
IC830_17590	COG4608	Belongs to the ABC transporter superfamily
IC830_17605	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IC830_17605	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
IC830_17630	COG0772	Belongs to the SEDS family
IC830_17640	COG1136	(ABC) transporter
IC830_17660	COG3275	phosphorelay sensor kinase activity
IC830_17665	COG3279	Response regulator of the LytR AlgR family
IC830_17675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IC830_17700	COG0786	glutamate:sodium symporter activity
IC830_17715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC830_17755	COG2259	Doxx family
IC830_17770	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IC830_17780	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IC830_17820	COG3123	guanosine phosphorylase activity
IC830_17855	COG0583	DNA-binding transcription factor activity
IC830_17860	COG0561	phosphatase activity
IC830_17885	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IC830_17890	COG2162	N-hydroxyarylamine O-acetyltransferase activity
IC830_17915	COG1028	Short-chain dehydrogenase reductase Sdr
IC830_17925	COG1917	Cupin 2, conserved barrel domain protein
IC830_17940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC830_17945	COG0800	Aldolase
IC830_17970	COG0823	Involved in the tonB-independent uptake of proteins
IC830_18005	COG1357	PFAM Pentapeptide repeats (8 copies)
IC830_18010	COG3047	cAMP biosynthetic process
IC830_18045	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
IC830_18055	COG0583	DNA-binding transcription factor activity
IC830_18080	COG0546	phosphoglycolate phosphatase activity
IC830_18110	COG2610	gluconate transmembrane transporter activity
IC830_18120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC830_18155	COG1028	Short-chain dehydrogenase reductase Sdr
IC830_18165	COG3005	denitrification pathway
IC830_18180	COG0352	thiamine-phosphate diphosphorylase activity
IC830_18190	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IC830_18195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IC830_18200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC830_18205	COG1116	anion transmembrane transporter activity
IC830_18210	COG0351	phosphomethylpyrimidine kinase
IC830_18220	COG0312	modulator of DNA gyrase
IC830_18225	COG1901	pseudouridine methyltransferase
IC830_18280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IC830_18320	COG0811	peptide transport
IC830_18325	COG0848	biopolymer transport protein
IC830_18370	COG1121	(ABC) transporter
IC830_18375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IC830_18390	COG1770	oligopeptidase
IC830_18405	COG1166	arginine decarboxylase activity
IC830_18415	COG4067	protein conserved in archaea
IC830_18415	COG0189	ligase activity
IC830_18470	COG2199	diguanylate cyclase activity
IC830_18555	COG0415	Belongs to the DNA photolyase family
IC830_18575	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IC830_18575	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IC830_18580	COG1765	OsmC-like protein
IC830_18585	COG0110	maltose O-acetyltransferase activity
IC830_18625	COG1011	Hydrolase
IC830_18645	COG3338	carbonate dehydratase activity
IC830_18650	COG2067	long-chain fatty acid transport protein
IC830_18655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC830_18660	COG0577	efflux transmembrane transporter activity
IC830_18660	COG1136	(ABC) transporter
IC830_18700	COG1609	Transcriptional regulator
IC830_18705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC830_18720	COG1840	ABC-type Fe3 transport system, periplasmic component
IC830_18755	COG2990	Protein conserved in bacteria
IC830_18760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IC830_18765	COG2866	Carboxypeptidase
IC830_18775	COG0583	DNA-binding transcription factor activity
IC830_18820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IC830_18845	COG1815	bacterial-type flagellum-dependent cell motility
IC830_18850	COG1558	bacterial-type flagellum-dependent cell motility
IC830_18865	COG4787	bacterial-type flagellum-dependent cell motility
IC830_18880	COG1706	bacterial-type flagellum-dependent cell motility
IC830_18890	COG4786	Flagellar basal body rod
IC830_18890	COG1256	bacterial-type flagellum assembly
IC830_18895	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
IC830_18915	COG1304	FMN binding
IC830_18945	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IC830_18950	COG0459	protein refolding
IC830_18965	COG1280	lysine exporter protein (LysE YggA)
IC830_19055	COG0346	lactoylglutathione lyase activity
IC830_19080	COG1335	isochorismatase
IC830_19090	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IC830_19115	COG0583	DNA-binding transcription factor activity
IC830_19130	COG3713	MltA-interacting MipA family protein
IC830_19135	COG3015	lipoprotein NlpE involved in copper resistance
IC830_19320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IC830_19340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IC830_19360	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IC830_19365	COG0252	asparaginase activity
IC830_19370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IC830_19375	COG0583	DNA-binding transcription factor activity
IC830_19390	COG3122	Protein conserved in bacteria
IC830_19400	COG1028	Short-chain dehydrogenase reductase Sdr
IC830_19410	COG1063	alcohol dehydrogenase
IC830_19440	COG0513	Belongs to the DEAD box helicase family
IC830_19485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
IC830_19485	COG2207	Transcriptional regulator
IC830_19525	COG0401	homolog of Blt101
IC830_19540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IC830_19595	COG0848	biopolymer transport protein
IC830_19600	COG0811	peptide transport
IC830_19605	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IC830_19620	COG0748	coenzyme F420 binding
IC830_19635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IC830_19650	COG2211	Major facilitator Superfamily
IC830_19690	COG2211	Major facilitator Superfamily
IC830_19790	COG2249	NAD(P)H dehydrogenase (quinone) activity
IC830_19805	COG1505	serine-type exopeptidase activity
IC830_19825	COG2067	long-chain fatty acid transport protein
IC830_19835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IC830_19900	COG0842	Transport permease protein
IC830_19905	COG1131	(ABC) transporter
IC830_19920	COG2706	6-phosphogluconolactonase activity
IC830_19930	COG1881	PFAM PEBP family protein
IC830_19960	COG2213	PTS system mannitol-specific
IC830_19965	COG1063	alcohol dehydrogenase
IC830_19975	COG1072	(Pantothenic acid kinase))
IC830_19980	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
IC830_20015	COG3314	Sporulation integral membrane protein YlbJ
IC830_20045	COG0583	DNA-binding transcription factor activity
IC830_20050	COG2814	Major facilitator Superfamily
IC830_20065	COG0697	spore germination
IC830_20095	COG2207	Transcriptional regulator
IC830_20100	COG1280	lysine exporter protein (LysE YggA)
IC830_20110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IC830_20125	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
IC830_20150	COG1612	heme a metabolic process
IC830_20155	COG0109	protoheme IX farnesyltransferase activity
IC830_20160	COG0545	Peptidyl-prolyl cis-trans isomerase
IC830_20190	COG1278	Cold shock
IC830_20195	COG3036	rescue of stalled ribosome
IC830_20205	COG2199	diguanylate cyclase activity
IC830_20225	COG0577	efflux transmembrane transporter activity
IC830_20225	COG1136	(ABC) transporter
IC830_20250	COG2133	pyrroloquinoline quinone binding
IC830_20260	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
IC830_20300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IC830_20310	COG3186	Phenylalanine-4-hydroxylase
IC830_20315	COG2154	pterin-4-alpha-carbinolamine dehydratase
IC830_20335	COG3530	Putative quorum-sensing-regulated virulence factor
IC830_20340	COG0513	Belongs to the DEAD box helicase family
IC830_20345	COG4628	conserved protein (DUF2132)
IC830_20360	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IC830_20370	COG0523	cobalamin synthesis protein
IC830_20375	COG0513	Belongs to the DEAD box helicase family
IC830_20395	COG2200	EAL domain
IC830_20425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IC830_20440	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IC830_20445	COG0513	Belongs to the DEAD box helicase family
IC830_20455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IC830_20470	COG5413	integral membrane protein
IC830_20485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IC830_20490	COG1960	acyl-CoA dehydrogenase activity
IC830_20515	COG1024	Enoyl-CoA hydratase
IC830_20520	COG1024	Enoyl-CoA hydratase
IC830_20530	COG1028	Short-chain dehydrogenase reductase Sdr
IC830_20545	COG1845	cytochrome c oxidase, subunit III
IC830_20550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IC830_20555	COG0109	protoheme IX farnesyltransferase activity
IC830_20630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IC830_20640	COG4160	amino acid transport
IC830_20690	COG0443	Heat shock 70 kDa protein
IC830_20695	COG2847	Copper chaperone PCu(A)C
IC830_20715	COG4607	ABC-type enterochelin transport system periplasmic component
IC830_20720	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IC830_20730	COG4604	ABC transporter, ATP-binding protein
IC830_20735	COG0789	Transcriptional regulator
IC830_20740	COG2207	Transcriptional regulator
IC830_20790	COG1879	ABC-type sugar transport system periplasmic component
IC830_20810	COG0745	RESPONSE REGULATOR receiver
IC830_20815	COG3119	arylsulfatase activity
IC830_20835	COG3119	arylsulfatase activity
IC830_20840	COG0641	radical SAM
IC830_20875	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IC830_20890	COG3111	PFAM Bacterial OB fold (BOF) protein
IC830_20935	COG1704	LemA family
IC830_20990	COG2207	Transcriptional regulator
IC830_21075	COG0583	DNA-binding transcription factor activity
IC830_21080	COG0583	DNA-binding transcription factor activity
IC830_21100	COG2197	response regulator
IC830_21115	COG2197	response regulator
IC830_21175	COG2076	Multidrug Resistance protein
IC830_21210	COG3290	protein histidine kinase activity
IC830_21215	COG4565	transcriptional regulatory protein
IC830_21260	COG0346	lactoylglutathione lyase activity
IC830_21350	COG2176	DNA-directed DNA polymerase activity
IC830_21380	COG2207	Transcriptional regulator
IC830_21385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IC830_21390	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IC830_21390	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IC830_21395	COG0509	glycine decarboxylation via glycine cleavage system
IC830_21400	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IC830_21440	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC830_21440	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IC830_21440	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IC830_21445	COG1105	Belongs to the carbohydrate kinase PfkB family
IC830_21475	COG0765	amino acid transport
IC830_21485	COG0765	amino acid transport
IC830_21495	COG0469	pyruvate kinase activity
IC830_21530	COG2207	Transcriptional regulator
IC830_21570	COG0546	phosphoglycolate phosphatase activity
IC830_21585	COG0513	Belongs to the DEAD box helicase family
IC830_21605	COG3038	cytochrome b561
IC830_21610	COG2353	YceI-like domain
IC830_21635	COG0737	Belongs to the 5'-nucleotidase family
IC830_21660	COG2067	long-chain fatty acid transport protein
IC830_21675	COG2050	protein possibly involved in aromatic compounds catabolism
IC830_21710	COG0484	heat shock protein binding
IC830_21735	COG4181	ATPase activity
IC830_21750	COG1984	allophanate hydrolase subunit 2
IC830_21760	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IC830_21780	COG0583	DNA-binding transcription factor activity
IC830_21805	COG0023	Translation Initiation Factor
IC830_21830	COG0589	response to stress
IC830_21865	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IC830_21900	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IC830_21905	COG4149	molybdate abc transporter
IC830_21910	COG0725	ABC transporter, periplasmic molybdate-binding protein
IC830_21915	COG1492	cobalamin metabolic process
IC830_21930	COG4067	protein conserved in archaea
IC830_21930	COG0189	ligase activity
IC830_21945	COG0534	Mate efflux family protein
IC830_21950	COG0602	queuosine metabolic process
IC830_22000	COG0243	molybdopterin cofactor binding
IC830_22005	COG0583	DNA-binding transcription factor activity
IC830_22020	COG2197	response regulator
IC830_22025	COG2197	response regulator
IC830_22065	COG3118	belongs to the thioredoxin family
IC830_22145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IC830_22220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IC830_22275	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
IC830_22285	COG1288	antiporter activity
IC830_22305	COG3040	lipid binding
IC830_22330	COG0420	3'-5' exonuclease activity
IC830_22435	COG2815	serine threonine protein kinase
IC830_22435	COG0515	serine threonine protein kinase
IC830_22490	COG1116	anion transmembrane transporter activity
IC830_22495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IC830_22505	COG3707	response regulator
IC830_22520	COG1648	precorrin-2 dehydrogenase activity
IC830_22520	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IC830_22525	COG0243	molybdopterin cofactor binding
IC830_22535	COG0814	amino acid
IC830_22560	COG1785	Belongs to the alkaline phosphatase family
IC830_22575	COG0745	RESPONSE REGULATOR receiver
IC830_22590	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
IC830_22600	COG1609	Transcriptional regulator
IC830_22605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IC830_22610	COG1879	ABC-type sugar transport system periplasmic component
IC830_22615	COG1172	Belongs to the binding-protein-dependent transport system permease family
IC830_22625	COG1869	D-ribose catabolic process
IC830_22700	COG5001	Diguanylate cyclase
IC830_22700	COG3300	MHYT domain
IC830_22710	COG0330	HflC and HflK could
IC830_22725	COG0517	IMP dehydrogenase activity
IC830_22725	COG4175	Glycine betaine
IC830_22730	COG4176	ABC-type proline glycine betaine transport system permease component
IC830_22750	COG1309	transcriptional regulator
IC830_22755	COG3706	GGDEF domain
IC830_22760	COG1028	Short-chain dehydrogenase reductase Sdr
IC830_22775	COG1024	Enoyl-CoA hydratase
IC830_22780	COG1960	acyl-CoA dehydrogenase activity
IC830_22840	COG3264	Mechanosensitive ion channel
IC830_22840	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
IC830_22850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IC830_22855	COG1271	oxidase subunit
IC830_22870	COG0384	phenazine biosynthesis protein PhzF
IC830_22880	COG0789	Transcriptional regulator
IC830_22890	COG3474	cytochrome
IC830_22955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IC830_22960	COG0516	GMP reductase activity
IC830_22980	COG4989	oxidoreductase activity
IC830_23005	COG1914	H( )-stimulated, divalent metal cation uptake system
IC830_23090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IC830_23100	COG0840	transmembrane signaling receptor activity
IC830_23165	COG3005	denitrification pathway
IC830_23195	COG1280	lysine exporter protein (LysE YggA)
IC830_23210	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IC830_23235	COG1522	sequence-specific DNA binding
IC830_23275	COG2827	Endonuclease containing a URI domain
IC830_23290	COG2926	Belongs to the UPF0265 family
IC830_23305	COG5002	protein histidine kinase activity
IC830_23305	COG0784	Response regulator, receiver
IC830_23305	COG2205	protein histidine kinase activity
IC830_23365	COG0783	Belongs to the Dps family