locus-tag	class	description
FORC8_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FORC8_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FORC8_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FORC8_0004	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FORC8_0006	ENOG4108ZNX	Heat shock protein
FORC8_0007	ENOG4105JKW	Valine--pyruvate aminotransferase
FORC8_0008	ENOG4107T9C	Alpha amylase catalytic region
FORC8_0009	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FORC8_0010	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
FORC8_0013	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
FORC8_0016	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
FORC8_0017	ENOG4105CHU	acetyl-coa acetyltransferase
FORC8_0018	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FORC8_0019	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FORC8_0020	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FORC8_0021	ENOG4108RR8	protoporphyrinogen oxidase
FORC8_0023	ENOG4105WMR	Protein CrcB homolog
FORC8_0024	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FORC8_0026	ENOG4105D06	uba thif-type nad fad binding protein
FORC8_0027	ENOG4105WHD	thiamine biosynthesis protein ThiS
FORC8_0028	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FORC8_0029	ENOG4105D41	biosynthesis protein thiH
FORC8_0030	ENOG4105DC7	peptidase M24
FORC8_0030	ENOG4105DC7	peptidase M24
FORC8_0036	ENOG4105E18	UPF0276 protein
FORC8_0038	ENOG4105C4R	Atp-dependent dna helicase
FORC8_0039	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FORC8_0042	ENOG4105FR1	rard protein
FORC8_0043	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FORC8_0045	ENOG4105EX9	Membrane
FORC8_0046	ENOG4105C9X	ppx gppa phosphatase
FORC8_0047	ENOG4105C1J	atp-dependent rna helicase
FORC8_0048	ENOG4105K63	Thioredoxin
FORC8_0049	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FORC8_0051	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
FORC8_0052	ENOG4108ZIT	Ferredoxin, 2FE-2S
FORC8_0053	ENOG4107QK7	reductase
FORC8_0055	ENOG410601J	HemY protein
FORC8_0056	ENOG4105ECF	c-methyltransferase
FORC8_0057	ENOG41076E6	Uroporphyrinogen-III Synthase
FORC8_0058	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FORC8_0059	ENOG4107T0K	Adenylate cyclase
FORC8_0060	ENOG4105XQ6	frataxin-like protein
FORC8_0061	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FORC8_0062	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FORC8_0064	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FORC8_0065	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
FORC8_0066	ENOG4105BZU	Histidine kinase
FORC8_0067	ENOG4106IUH	DTW domain containing protein
FORC8_0070	ENOG4105DQF	Hydrolase
FORC8_0071	ENOG4108EUD	Lysophospholipase
FORC8_0072	ENOG410829K	Lysine exporter protein (Lyse ygga)
FORC8_0073	ENOG4105D58	Diguanylate phosphodiesterase
FORC8_0074	ENOG41082YX	Transcriptional regulator, arsr family
FORC8_0075	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FORC8_0085	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
FORC8_0087	ENOG4106H78	methyltransferase
FORC8_0088	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FORC8_0089	ENOG4105CAK	Cell division ATP-binding protein ftsE
FORC8_0090	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
FORC8_0091	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FORC8_0092	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
FORC8_0093	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
FORC8_0094	ENOG4105X6C	Flagellar basal body-associated protein FliL
FORC8_0095	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
FORC8_0096	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
FORC8_0097	ENOG4105E55	glycerol-3-phosphate acyltransferase
FORC8_0098	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FORC8_0100	ENOG4107R73	Mate efflux family protein
FORC8_0101	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
FORC8_0104	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
FORC8_0105	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FORC8_0107	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FORC8_0109	ENOG4105JIM	Phosphatidylserine synthase
FORC8_0111	ENOG4105D4A	Cell wall formation (By similarity)
FORC8_0112	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FORC8_0113	ENOG4105CS9	pantothenic acid kinase
FORC8_0115	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FORC8_0116	ENOG4105PM1	preprotein translocase subunit SecE
FORC8_0117	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FORC8_0118	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FORC8_0119	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FORC8_0120	ENOG4108VZM	50s ribosomal protein L10
FORC8_0121	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FORC8_0122	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FORC8_0123	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FORC8_0124	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
FORC8_0125	ENOG4105E09	nadh pyrophosphatase
FORC8_0128	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FORC8_0129	ENOG4108RG0	uracil-dna glycosylase
FORC8_0130	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
FORC8_0131	ENOG4105R2J	Conserved Protein
FORC8_0135	ENOG4105C12	Phosphoribosylglycinamide synthetase
FORC8_0136	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FORC8_0138	ENOG4105W1Y	Transcriptional regulator
FORC8_0139	ENOG4108M3R	transcriptional activator CadC
FORC8_0141	ENOG4105D5Q	Arginine ornithine antiporter
FORC8_0142	ENOG4105CXN	decarboxylase
FORC8_0143	ENOG4105BZU	Histidine kinase
FORC8_0144	ENOG4105C5H	ABC transporter
FORC8_0145	ENOG4107XZQ	multidrug resistance protein
FORC8_0146	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
FORC8_0147	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FORC8_0148	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FORC8_0149	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FORC8_0150	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FORC8_0151	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FORC8_0152	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FORC8_0155	ENOG4105D8G	Major Facilitator superfamily
FORC8_0156	ENOG4105BZU	Histidine kinase
FORC8_0157	ENOG4105C9Q	fumarate hydratase class II
FORC8_0160	ENOG4107QN1	sodium solute
FORC8_0162	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
FORC8_0164	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FORC8_0165	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FORC8_0166	ENOG4108IJ0	Aspartate ammonia-lyase
FORC8_0167	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
FORC8_0168	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FORC8_0170	ENOG4105E0F	Histidine kinase
FORC8_0171	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FORC8_0172	ENOG4108SPG	Periplasmic Protein
FORC8_0173	ENOG41076HS	cation diffusion facilitator family transporter
FORC8_0174	ENOG4105CTQ	phosphohexokinase
FORC8_0175	ENOG4107QI1	Mate efflux family protein
FORC8_0176	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FORC8_0177	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FORC8_0180	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FORC8_0181	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
FORC8_0182	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FORC8_0184	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
FORC8_0185	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
FORC8_0186	ENOG4105E33	succinate dehydrogenase
FORC8_0188	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
FORC8_0190	ENOG41062JF	Transcriptional regulator
FORC8_0192	ENOG41063SB	peptidase
FORC8_0193	ENOG4105D7W	serine acetyltransferase
FORC8_0194	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FORC8_0195	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
FORC8_0196	ENOG4107YZP	Rhodanese domain protein
FORC8_0197	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FORC8_0199	ENOG4108NVR	Methyl-accepting chemotaxis
FORC8_0200	ENOG4105C8P	)-transporter
FORC8_0201	ENOG4105DJ4	phosphatidylserine decarboxylase
FORC8_0202	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FORC8_0203	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
FORC8_0204	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FORC8_0205	ENOG4105K8N	protein family UPF0079, ATPase
FORC8_0206	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FORC8_0207	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FORC8_0208	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FORC8_0209	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
FORC8_0210	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FORC8_0211	ENOG4107QJR	hflk protein
FORC8_0212	ENOG4105EPW	hflc protein
FORC8_0214	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FORC8_0215	ENOG4108UV7	flagellar protein motX
FORC8_0216	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FORC8_0217	ENOG4105KPV	Transcriptional regulator
FORC8_0218	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FORC8_0219	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FORC8_0220	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FORC8_0221	ENOG4105C31	Tryptophanyl-tRNA synthetase
FORC8_0224	ENOG4105DDQ	anthranilate synthase
FORC8_0225	ENOG4105C8Y	Acetylornithine aminotransferase
FORC8_0227	ENOG4105C26	Dehydrogenase
FORC8_0229	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
FORC8_0230	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
FORC8_0231	ENOG4105YP7	UPF0270 protein
FORC8_0232	ENOG4105DNZ	Alpha Beta Hydrolase
FORC8_0234	ENOG4105C5H	ABC transporter
FORC8_0235	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
FORC8_0238	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FORC8_0239	ENOG4105D44	asparaginase
FORC8_0240	ENOG41069P5	Protein slyX homolog
FORC8_0242	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FORC8_0243	ENOG4105WWK	YheO domain protein
FORC8_0244	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
FORC8_0245	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
FORC8_0246	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
FORC8_0247	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FORC8_0248	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FORC8_0249	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FORC8_0250	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FORC8_0251	ENOG4105W53	bacterioferritin-associated ferredoxin
FORC8_0252	ENOG4108UQY	Iron-storage protein
FORC8_0253	ENOG4105C6K	Malic enzyme
FORC8_0254	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
FORC8_0255	ENOG4105C28	cystathionine
FORC8_0256	ENOG4105CFH	Aspartokinase
FORC8_0257	ENOG4105SYT	Methylenetetrahydrofolate reductase
FORC8_0259	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
FORC8_0260	ENOG4105CWC	Acetylornithine deacetylase
FORC8_0261	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FORC8_0262	ENOG4105CAS	nag kinase
FORC8_0263	ENOG4105CDH	Citrulline--aspartate ligase
FORC8_0264	ENOG4105CH7	arginosuccinase
FORC8_0266	ENOG4105EHV	domain protein
FORC8_0268	ENOG4108JQC	penicillin-binding protein 1A
FORC8_0273	ENOG4105E4G	Type IV pilus
FORC8_0274	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FORC8_0275	ENOG4105D49	3-dehydroquinate synthase
FORC8_0277	ENOG4105DFE	Dna adenine methylase
FORC8_0278	ENOG4105DJV	ribulose-phosphate 3-epimerase
FORC8_0279	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FORC8_0280	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
FORC8_0281	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FORC8_0282	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FORC8_0284	ENOG4105CDU	Replicative dna helicase
FORC8_0285	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FORC8_0287	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
FORC8_0288	ENOG4107QP8	phosphohexose isomerase
FORC8_0290	ENOG4105MYN	Zinc uptake regulation protein
FORC8_0291	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FORC8_0295	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
FORC8_0296	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
FORC8_0297	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
FORC8_0298	ENOG4105EEQ	Na H antiporter
FORC8_0299	ENOG4105C3R	Methionine synthase
FORC8_0300	ENOG4105CFH	Aspartokinase
FORC8_0302	ENOG4105C5R	Aminotransferase
FORC8_0304	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FORC8_0305	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FORC8_0306	ENOG41086KC	Transcriptional regulator
FORC8_0308	ENOG4108UUM	single-stranded DNA-binding protein
FORC8_0309	ENOG41062P1	Diguanylate cyclase phosphodiesterase
FORC8_0313	ENOG4105E4G	Type IV pilus
FORC8_0316	ENOG4107QHF	type ii secretion system protein e
FORC8_0317	ENOG4105D7Q	type ii secretion system
FORC8_0326	ENOG4105DFF	Rod shape-determining protein mreb
FORC8_0327	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
FORC8_0328	ENOG4105VQ7	Rod shape-determining protein MreD
FORC8_0329	ENOG4108Z03	MAF-like protein
FORC8_0330	ENOG4105C03	ribonuclease
FORC8_0331	ENOG4105QD6	exported protein
FORC8_0333	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
FORC8_0334	ENOG4108IAB	Phoh family
FORC8_0335	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
FORC8_0336	ENOG4105K3M	)-transporter
FORC8_0337	ENOG4105D3G	Pseudouridine synthase
FORC8_0338	ENOG4105C5I	Dehydrogenase
FORC8_0339	ENOG4105N42	UPF0307 protein
FORC8_0340	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
FORC8_0341	ENOG4105CJW	magnesium transporter
FORC8_0342	ENOG41080Z8	PHOSPHOCARRIER protein
FORC8_0343	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FORC8_0344	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
FORC8_0345	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
FORC8_0346	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FORC8_0347	ENOG4108IUZ	ABC transporter
FORC8_0348	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
FORC8_0350	ENOG4105C2X	Arabinose 5-phosphate isomerase
FORC8_0352	ENOG4105DHJ	ABC, transporter
FORC8_0353	ENOG4105CY3	ABC transporter, permease
FORC8_0354	ENOG4107PE3	Mammalian cell entry related domain protein
FORC8_0355	ENOG4105E3I	toluene tolerance
FORC8_0357	ENOG4105VFK	BolA family
FORC8_0358	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FORC8_0359	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
FORC8_0360	ENOG4105KME	endoribonuclease L-psp
FORC8_0361	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
FORC8_0362	ENOG4105CXT	aspartate transcarbamylase
FORC8_0363	ENOG4105DBV	ornithine carbamoyltransferase
FORC8_0364	ENOG4105CEU	Arginine dihydrolase
FORC8_0367	ENOG4108MJ3	acetyltransferase
FORC8_0369	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FORC8_0370	ENOG4105MYG	DNA polymerase iii, chi subunit
FORC8_0371	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FORC8_0372	ENOG4108M8S	permease YjgP YjgQ family protein
FORC8_0373	ENOG4108K5H	permease YjgP YjgQ family protein
FORC8_0375	ENOG4105EXU	Membrane
FORC8_0376	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
FORC8_0378	ENOG4105VZJ	PTS System
FORC8_0379	ENOG4105CK1	PTS System
FORC8_0380	ENOG4105VCP	PTS System
FORC8_0381	ENOG4105F8D	glycoside hydrolase family 4
FORC8_0382	ENOG410901P	UPF0249 protein
FORC8_0384	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FORC8_0386	ENOG4105C26	Dehydrogenase
FORC8_0387	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_0388	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
FORC8_0389	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
FORC8_0390	ENOG4105CEN	a g-specific adenine glycosylase
FORC8_0391	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FORC8_0393	ENOG4105CSV	Glutaminase
FORC8_0394	ENOG4105CSA	Coproporphyrinogen iii oxidase
FORC8_0395	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FORC8_0397	ENOG4105VZ9	UPF0235 protein
FORC8_0398	ENOG4108VIA	integral membrane protein
FORC8_0399	ENOG4105II7	pyrroline-5-carboxylate reductase
FORC8_0400	ENOG4105DFA	alanine racemase domain protein
FORC8_0401	ENOG4105CZX	twitching motility protein
FORC8_0402	ENOG4105CZX	twitching motility protein
FORC8_0403	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FORC8_0404	ENOG4108UJU	UPF0301 protein
FORC8_0405	ENOG4105D7Z	glutathione synthase
FORC8_0406	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FORC8_0407	ENOG4105RWS	endonuclease I
FORC8_0408	ENOG4105GPY	SprT protein
FORC8_0410	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FORC8_0412	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FORC8_0413	ENOG4108R4R	Iron-regulated virulence regulatory protein
FORC8_0414	ENOG4105D05	Receptor
FORC8_0415	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FORC8_0416	ENOG4105BZA	Phosphoglycerate kinase
FORC8_0417	ENOG4105D2N	Aldolase
FORC8_0418	ENOG4105D64	Mechanosensitive ion channel
FORC8_0419	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
FORC8_0421	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
FORC8_0422	ENOG4105MPN	Membrane
FORC8_0423	ENOG4108JQ1	Dehydrogenase
FORC8_0424	ENOG4105E66	phosphoriboisomerase A
FORC8_0425	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FORC8_0426	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
FORC8_0428	ENOG4105D0A	hydroxylase
FORC8_0429	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
FORC8_0432	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
FORC8_0433	ENOG4105Y75	tpr repeat protein
FORC8_0434	ENOG4108IYU	L-aspartate oxidase
FORC8_0435	ENOG4105EMN	RNA polymerase sigma factor
FORC8_0436	ENOG41069PW	sigma-e factor negative regulatory protein
FORC8_0439	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FORC8_0440	ENOG4105C3F	Signal peptidase i
FORC8_0441	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FORC8_0442	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FORC8_0443	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
FORC8_0444	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FORC8_0445	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
FORC8_0446	ENOG4105BZU	Histidine kinase
FORC8_0447	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FORC8_0448	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FORC8_0449	ENOG4105DXN	mazG family
FORC8_0450	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FORC8_0451	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FORC8_0452	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
FORC8_0453	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
FORC8_0454	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FORC8_0455	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
FORC8_0456	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FORC8_0457	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FORC8_0459	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FORC8_0460	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FORC8_0461	ENOG4107TH8	cina domain protein
FORC8_0462	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FORC8_0463	ENOG4105Y3E	Modulates RecA activity (By similarity)
FORC8_0464	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FORC8_0465	ENOG4105CFH	Aspartokinase
FORC8_0466	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
FORC8_0467	ENOG4106AFN	Lyase and sodium transporter (By similarity)
FORC8_0468	ENOG4107QSA	Oxaloacetate decarboxylase
FORC8_0469	ENOG4105D9Q	decarboxylase (Beta subunit)
FORC8_0470	ENOG4105CPQ	Dehydrogenase
FORC8_0471	ENOG4105W39	Membrane
FORC8_0473	ENOG4105D9M	gamma-glutamylcysteine synthetase
FORC8_0475	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
FORC8_0476	ENOG4108JU6	CBS domain protein
FORC8_0477	ENOG4106KVJ	cytochrome C assembly protein
FORC8_0478	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC8_0479	ENOG4105K5M	30s ribosomal protein S16
FORC8_0480	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FORC8_0481	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FORC8_0482	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FORC8_0483	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
FORC8_0484	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
FORC8_0485	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FORC8_0486	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
FORC8_0487	ENOG4105D7Q	type ii secretion system
FORC8_0488	ENOG4107QHF	type ii secretion system protein e
FORC8_0490	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FORC8_0492	ENOG41073TP	transcriptional regulator
FORC8_0493	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
FORC8_0494	ENOG4107QSN	dihydrolipoamide acetyltransferase
FORC8_0495	ENOG4107QN2	dihydrolipoyl dehydrogenase
FORC8_0496	ENOG410630P	Transcriptional regulator
FORC8_0497	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FORC8_0498	ENOG41077A9	carbonic anhydrase
FORC8_0499	ENOG4105CHH	sulfate transporter
FORC8_0500	ENOG4105DA5	(ABC) transporter
FORC8_0501	ENOG4105E3A	(ABC) transporter
FORC8_0502	ENOG4105D1S	lipid A biosynthesis
FORC8_0503	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
FORC8_0504	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
FORC8_0505	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC8_0506	ENOG4105DJ0	Poly(A) Polymerase
FORC8_0507	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
FORC8_0508	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC8_0509	ENOG4105PW4	Sugar fermentation stimulation protein homolog
FORC8_0510	ENOG4105CQ7	ATP-dependent helicase
FORC8_0511	ENOG4105BZ4	penicillin-binding protein
FORC8_0512	ENOG4105D78	K07001 NTE family protein
FORC8_0513	ENOG4107QIJ	Aconitate hydratase 2
FORC8_0514	ENOG4105XTV	UPF0231 protein
FORC8_0515	ENOG4108YZA	Nitrogen regulatory protein pii
FORC8_0519	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FORC8_0522	ENOG4105E2D	ec 3.2.1.52
FORC8_0523	ENOG4105RD7	BadF BadG BcrA BcrD
FORC8_0525	ENOG4108JQ7	(ABC) transporter
FORC8_0526	ENOG4105C3U	ABC transporter
FORC8_0527	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FORC8_0529	ENOG4107QRA	Extracellular solute-binding protein, family 5
FORC8_0530	ENOG4105BZU	Histidine kinase
FORC8_0531	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
FORC8_0532	ENOG4105IPI	Membrane
FORC8_0534	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FORC8_0535	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
FORC8_0537	ENOG4105BZS	acriflavin resistance protein
FORC8_0538	ENOG4105DR5	peptidase
FORC8_0539	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FORC8_0542	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
FORC8_0543	ENOG4107QE9	Inherit from COG: Membrane
FORC8_0544	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FORC8_0545	ENOG4105HBR	Rna-binding protein
FORC8_0546	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
FORC8_0547	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FORC8_0548	ENOG4105EEI	dihydropteroate synthase
FORC8_0549	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FORC8_0552	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FORC8_0553	ENOG4105CHV	Transcription elongation factor NusA
FORC8_0554	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FORC8_0555	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FORC8_0556	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FORC8_0557	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FORC8_0558	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FORC8_0559	ENOG4105RT1	May be involved in cell division (By similarity)
FORC8_0561	ENOG4105C3S	Mate efflux family protein
FORC8_0562	ENOG4106RZ4	Peptidase U32
FORC8_0563	ENOG4105CFP	Peptidase U32
FORC8_0564	ENOG4105BZU	Histidine kinase
FORC8_0565	ENOG4105XPQ	lipid carrier protein
FORC8_0566	ENOG4108YYD	acetyltransferase
FORC8_0570	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FORC8_0572	ENOG4105EYA	deoxyribonuclease
FORC8_0573	ENOG4105D9N	nucleoside
FORC8_0574	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
FORC8_0575	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
FORC8_0576	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
FORC8_0577	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FORC8_0579	ENOG4105EAC	phosphoserine phosphatase
FORC8_0581	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FORC8_0582	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FORC8_0583	ENOG4105ETT	transcriptional Regulator, LysR family
FORC8_0585	ENOG4108IQE	Amp-dependent synthetase and ligase
FORC8_0603	ENOG41064T2	transcriptional regulator, lysR family
FORC8_0604	ENOG4105E5D	amino acid
FORC8_0605	ENOG4105FK9	beta-D-galactosidase beta subunit
FORC8_0606	ENOG4105CNT	hydrolase family 2
FORC8_0607	ENOG4105CQ4	Transcriptional regulator
FORC8_0608	ENOG4105CMR	udp-glucose 4-epimerase
FORC8_0609	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
FORC8_0610	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
FORC8_0611	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FORC8_0614	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FORC8_0615	ENOG41060NJ	transcriptional regulator
FORC8_0616	ENOG4108Y51	tRNA-binding protein
FORC8_0620	ENOG4107RX3	Mg2 transporter protein cora family protein
FORC8_0621	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FORC8_0622	ENOG4105E98	transcriptional regulator DeoR family
FORC8_0623	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FORC8_0624	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FORC8_0625	ENOG4105CXY	transporter
FORC8_0626	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
FORC8_0627	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
FORC8_0628	ENOG4105X2V	dna damage-inducible protein
FORC8_0629	ENOG4105EVZ	LysR family transcriptional regulator
FORC8_0631	ENOG4105E68	Sulfatase
FORC8_0632	ENOG4105DSY	exodeoxyribonuclease V, gamma
FORC8_0634	ENOG4107QKA	exodeoxyribonuclease V beta
FORC8_0635	ENOG4107QYX	exodeoxyribonuclease v alpha
FORC8_0636	ENOG4107QZM	n-acetylglutamate synthase
FORC8_0638	ENOG4105CA3	membrane-bound lytic murein transglycosylase
FORC8_0639	ENOG4105CUZ	uba thif-type nad fad binding protein
FORC8_0640	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
FORC8_0641	ENOG4105BZU	Histidine kinase
FORC8_0642	ENOG4105C9B	Cysteine desulfurase
FORC8_0643	ENOG4107S0N	DJ-1 family
FORC8_0644	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
FORC8_0649	ENOG4105K6V	RNA polymerase
FORC8_0652	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FORC8_0653	ENOG4105IEY	(LipO)protein
FORC8_0654	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
FORC8_0655	ENOG4105M85	Bola protein
FORC8_0657	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FORC8_0658	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FORC8_0659	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FORC8_0660	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FORC8_0661	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FORC8_0662	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
FORC8_0663	ENOG4105CJ2	(LipO)protein
FORC8_0666	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FORC8_0667	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FORC8_0668	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FORC8_0671	ENOG4105C8J	)-transporter
FORC8_0673	ENOG4105W1I	UPF0253 protein
FORC8_0675	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FORC8_0676	ENOG4108R96	Methyltransferase, YaeB family
FORC8_0677	ENOG4105NRA	50s ribosomal protein l31 type b
FORC8_0678	ENOG4105CFC	Transporter
FORC8_0679	ENOG4108UPT	UPF0178 protein
FORC8_0684	ENOG4105WP7	tRNA pseudouridine synthase C
FORC8_0685	ENOG4105DR9	pseudouridine synthase
FORC8_0686	ENOG4108T8E	UPF0325 protein
FORC8_0687	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
FORC8_0688	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FORC8_0689	ENOG4105CE9	30S ribosomal protein S2
FORC8_0690	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FORC8_0691	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FORC8_0692	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FORC8_0693	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FORC8_0694	ENOG4105KNE	Phosphatidate cytidylyltransferase
FORC8_0695	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FORC8_0696	ENOG4105DZP	Membrane-associated zinc metalloprotease
FORC8_0698	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
FORC8_0699	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FORC8_0700	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FORC8_0701	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FORC8_0702	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FORC8_0703	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FORC8_0704	ENOG4105C0B	DNA polymerase III (alpha subunit)
FORC8_0705	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FORC8_0706	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FORC8_0708	ENOG4108YZA	Nitrogen regulatory protein pii
FORC8_0709	ENOG4107NA1	Endonuclease Exonuclease phosphatase
FORC8_0711	ENOG4105E9H	Lytic Murein transglycosylase
FORC8_0712	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FORC8_0713	ENOG4105D1A	Methyltransferase
FORC8_0714	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FORC8_0715	ENOG4107RZZ	dna polymerase iii epsilon subunit
FORC8_0721	ENOG4107QPN	acyl-Coa dehydrogenase
FORC8_0722	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
FORC8_0723	ENOG4105E7A	Glutamine amidotransferase
FORC8_0724	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FORC8_0725	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FORC8_0726	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FORC8_0727	ENOG4105C2W	permease
FORC8_0730	ENOG4105CS1	NAD(P)H quinone oxidoreductase
FORC8_0731	ENOG4105K89	arsenate reductase
FORC8_0732	ENOG4105ERG	peptidase m48, ste24p
FORC8_0735	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC8_0736	ENOG4105RH4	Glycine cleavage system transcriptional repressor
FORC8_0738	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FORC8_0741	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FORC8_0742	ENOG4105KUZ	arsenate reductase
FORC8_0746	ENOG4105QZU	Inner membrane protein YfeZ
FORC8_0747	ENOG4105EZR	dyp-type peroxidase family protein
FORC8_0748	ENOG4105I03	Flagellin
FORC8_0749	ENOG4105I03	Flagellin
FORC8_0750	ENOG4105I03	Flagellin
FORC8_0751	ENOG41063QE	flagellar protein FlaG
FORC8_0752	ENOG4107BRV	flagellar capping protein
FORC8_0754	ENOG4105MQ3	flagellar protein FliS
FORC8_0755	ENOG4108JUA	Transcriptional regulator
FORC8_0756	ENOG4105BZU	Histidine kinase
FORC8_0757	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_0758	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
FORC8_0759	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
FORC8_0760	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FORC8_0762	ENOG4108JIR	Flagellum-specific ATP synthase
FORC8_0766	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FORC8_0767	ENOG4105DD5	Flagellar motor switch protein
FORC8_0768	ENOG4105VTB	flagellar biosynthesis protein fliO
FORC8_0769	ENOG4105CN7	Flagellar biosynthetic protein FliP
FORC8_0770	ENOG4105VS8	Flagellar biosynthetic protein fliq
FORC8_0771	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
FORC8_0772	ENOG4105D00	flagellar biosynthetic protein flhB
FORC8_0773	ENOG4105D7B	Flagellar biosynthesis protein flha
FORC8_0774	ENOG4105FZW	flagellar biosynthesis regulator FlhF
FORC8_0775	ENOG4107R21	site-determining protein
FORC8_0776	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FORC8_0777	ENOG4108VYJ	response regulator receiver protein
FORC8_0778	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
FORC8_0779	ENOG4105CBS	Chea signal transduction histidine kinase
FORC8_0780	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FORC8_0781	ENOG4107QJE	Chromosome Partitioning Protein
FORC8_0783	ENOG4108V3W	Chemotaxis protein, CheW
FORC8_0785	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
FORC8_0786	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
FORC8_0787	ENOG41060IM	Heme exporter protein
FORC8_0788	ENOG4105X3C	heme exporter protein
FORC8_0789	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
FORC8_0790	ENOG4105DA4	cytochrome c-type biogenesis protein
FORC8_0791	ENOG4107QX9	Thiol disulfide interChange protein
FORC8_0792	ENOG4108M1T	Cytochrome c-type biogenesis protein
FORC8_0794	ENOG410903C	(LipO)protein
FORC8_0795	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FORC8_0796	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FORC8_0800	ENOG4105CHU	acetyl-coa acetyltransferase
FORC8_0801	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FORC8_0803	ENOG4107QXK	peptidase
FORC8_0804	ENOG4108BY2	phosphohistidine phosphatase
FORC8_0805	ENOG4108DG9	Smr protein MutS2
FORC8_0806	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
FORC8_0807	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FORC8_0808	ENOG4105EN6	Membrane
FORC8_0809	ENOG4108BPE	-transporting atpase
FORC8_0810	ENOG4105MH2	YfcL protein
FORC8_0811	ENOG4105Q8W	reductase
FORC8_0812	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
FORC8_0813	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FORC8_0814	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
FORC8_0815	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FORC8_0817	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FORC8_0818	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FORC8_0819	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FORC8_0820	ENOG4108S3P	Sporulation domain protein
FORC8_0821	ENOG4105E96	Colicin v production protein
FORC8_0822	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FORC8_0823	ENOG4105EJC	lysr family transcriptional regulator
FORC8_0824	ENOG4105I93	response regulator
FORC8_0825	ENOG4105WD1	Membrane
FORC8_0826	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FORC8_0827	ENOG4107QMP	dna polymerase iii subunits gamma and tau
FORC8_0828	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FORC8_0829	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FORC8_0830	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FORC8_0831	ENOG4105C44	Serine transporter
FORC8_0832	ENOG4105KME	endoribonuclease L-psp
FORC8_0833	ENOG4105CEM	UPF0597 protein
FORC8_0835	ENOG4105KRS	Proteinase inhibitor
FORC8_0836	ENOG4105Y3U	Transglycosylase-associated protein
FORC8_0838	ENOG41067V3	Antibiotic biosynthesis monooxygenase
FORC8_0839	ENOG4108UYE	Lactoylglutathione lyase
FORC8_0841	ENOG4105G6Z	alkaline phosphatase
FORC8_0844	ENOG4105DHI	Methyltransferase
FORC8_0845	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_0846	ENOG4105DSB	aldose 1-epimerase
FORC8_0847	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FORC8_0848	ENOG4105E0X	reductase
FORC8_0850	ENOG4105VUT	cytoplasmic protein
FORC8_0851	ENOG4105HDK	L-asparaginase
FORC8_0852	ENOG4105D07	Signal peptide peptidase, SppA
FORC8_0853	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FORC8_0854	ENOG41069NU	Nitroreductase
FORC8_0855	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FORC8_0857	ENOG4108RU0	short-chain dehydrogenase reductase
FORC8_0858	ENOG4105DGU	Histone deacetylase
FORC8_0859	ENOG4105E68	Sulfatase
FORC8_0860	ENOG4105YDX	UPF0352 protein
FORC8_0861	ENOG4106V8H	Nucleoid-associated protein
FORC8_0864	ENOG4105DFD	Na H antiporter
FORC8_0865	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FORC8_0866	ENOG4105EYW	Ion transport protein
FORC8_0867	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
FORC8_0868	ENOG4108EKI	Dehydrogenase
FORC8_0871	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FORC8_0872	ENOG4105M2J	Glutaredoxin
FORC8_0874	ENOG4105D3Y	Na H antiporter
FORC8_0875	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
FORC8_0876	ENOG4105EIY	sodium-type flagellar protein motY
FORC8_0877	ENOG4106WH9	Protein of unknown function (DUF2753)
FORC8_0878	ENOG4108UYE	Lactoylglutathione lyase
FORC8_0879	ENOG4105CSM	endonuclease III
FORC8_0880	ENOG4105DZB	Electron transport complex
FORC8_0881	ENOG4108UQQ	Electron transport complex
FORC8_0882	ENOG4105D6A	Electron transport complex
FORC8_0884	ENOG4108R3D	Electron transport complex
FORC8_0885	ENOG4105DGN	Electron transport complex
FORC8_0886	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FORC8_0887	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_0889	ENOG4105CHW	UPF0052 protein
FORC8_0890	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FORC8_0891	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
FORC8_0892	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FORC8_0893	ENOG4105M00	molybdopterin converting factor, subunit 1
FORC8_0894	ENOG4108ZAF	Molybdopterin
FORC8_0895	ENOG4107QSI	ABC, transporter
FORC8_0896	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FORC8_0897	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FORC8_0898	ENOG4105C3U	ABC transporter
FORC8_0899	ENOG4108JQ7	(ABC) transporter
FORC8_0900	ENOG4105CHF	Glutathione S-transferase
FORC8_0902	ENOG4107PU6	Membrane
FORC8_0903	ENOG4108DNC	Involved in acetate metabolism (By similarity)
FORC8_0904	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FORC8_0905	ENOG4105PQ6	UPF0208 membrane protein
FORC8_0907	ENOG4105C7J	ABC transporter, permease
FORC8_0908	ENOG4108JJB	ABC transporter
FORC8_0909	ENOG4107R28	alpha amylase, catalytic region
FORC8_0910	ENOG4105BZU	Histidine kinase
FORC8_0911	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
FORC8_0912	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FORC8_0913	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
FORC8_0915	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FORC8_0916	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
FORC8_0918	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FORC8_0919	ENOG4105D1F	ATP-binding protein
FORC8_0920	ENOG4105DBI	uridine monophosphokinase
FORC8_0922	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
FORC8_0924	ENOG4105CHH	sulfate transporter
FORC8_0925	ENOG4105C03	ribonuclease
FORC8_0927	ENOG4105EI2	Pseudouridine synthase
FORC8_0928	ENOG4108UHJ	MAF-like protein
FORC8_0929	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
FORC8_0930	ENOG4105VGS	50s ribosomal protein l32
FORC8_0931	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FORC8_0932	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FORC8_0933	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FORC8_0934	ENOG4105CHR	reductase
FORC8_0935	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FORC8_0936	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FORC8_0938	ENOG4105HHA	aminodeoxychorismate lyase
FORC8_0939	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FORC8_0940	ENOG4107QRG	dna polymerase iii
FORC8_0941	ENOG4105F8V	Hydrolase, tatD family
FORC8_0942	ENOG4105CI1	PTS System
FORC8_0944	ENOG4105C8J	)-transporter
FORC8_0946	ENOG4108NRW	Phospholipase, patatin family
FORC8_0947	ENOG4105CA9	Pyruvate kinase
FORC8_0948	ENOG4105DAG	ROK family
FORC8_0949	ENOG4107R88	Chemotaxis protein (CheV)
FORC8_0950	ENOG4105C0B	DNA polymerase III (alpha subunit)
FORC8_0953	ENOG4105UBK	short-chain dehydrogenase reductase
FORC8_0954	ENOG4105ERU	peptidase
FORC8_0955	ENOG4105CAT	Cytidine monophosphate kinase
FORC8_0956	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FORC8_0957	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FORC8_0958	ENOG4105Q4A	inner membrane protein yciS
FORC8_0959	ENOG4105CFV	Tetratricopeptide repeat protein
FORC8_0960	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FORC8_0961	ENOG4108J59	Extracellular solute-binding protein, family 5
FORC8_0964	ENOG4105CKK	Glycosyl transferase, family 2
FORC8_0966	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
FORC8_0968	ENOG4105DY2	Paraquat-inducible protein b
FORC8_0969	ENOG4105F1S	paraquat-inducible protein a
FORC8_0970	ENOG4105NQN	cytochrome C
FORC8_0972	ENOG4105DB1	molybdopterin oxidoreductase
FORC8_0973	ENOG4106WHD	Tetrathionate reductase
FORC8_0974	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FORC8_0975	ENOG4106AFQ	Histidine kinase
FORC8_0976	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FORC8_0977	ENOG4105EXG	Transcriptional regulator
FORC8_0979	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FORC8_0980	ENOG4105N6Y	Thioredoxin
FORC8_0983	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FORC8_0986	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
FORC8_0988	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FORC8_0989	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FORC8_0990	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FORC8_0991	ENOG4108W2Y	isochorismatase
FORC8_0992	ENOG41063TF	transcriptional regulator (AraC
FORC8_0995	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FORC8_0997	ENOG4105J12	Multidrug resistance protein mdtN
FORC8_0998	ENOG4105JQN	Transcriptional regulator
FORC8_1002	ENOG41062D9	Histidine kinase
FORC8_1003	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FORC8_1004	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_1005	ENOG4105CCT	upf0313 protein
FORC8_1009	ENOG4105DZ2	Transcriptional regulator
FORC8_1010	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FORC8_1012	ENOG4105K9H	YciI-like protein
FORC8_1013	ENOG4105NAU	thioesterase Superfamily protein
FORC8_1014	ENOG4107835	probably involved in intracellular septation (By similarity)
FORC8_1016	ENOG4105BZU	Histidine kinase
FORC8_1018	ENOG4105CK2	sodium dicarboxylate symporter
FORC8_1019	ENOG4105CEY	Amp-dependent synthetase and ligase
FORC8_1020	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
FORC8_1021	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FORC8_1022	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FORC8_1023	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FORC8_1024	ENOG4108I0Q	anthranilate phosphoribosyltransferase
FORC8_1025	ENOG4105DDQ	anthranilate synthase
FORC8_1026	ENOG4105CRQ	synthase (Component I)
FORC8_1027	ENOG4105DB7	PHP domain protein
FORC8_1028	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
FORC8_1030	ENOG4105FE9	pseudouridine synthase
FORC8_1031	ENOG4108W5H	UPF0263 protein
FORC8_1032	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FORC8_1034	ENOG4105CQ2	DNA polymerase
FORC8_1035	ENOG4105WH1	Two component transcriptional regulator luxr family
FORC8_1036	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FORC8_1041	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
FORC8_1046	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FORC8_1047	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FORC8_1048	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FORC8_1049	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FORC8_1052	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
FORC8_1054	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FORC8_1055	ENOG4105DVI	reductase, NrfD
FORC8_1056	ENOG4105DA4	cytochrome c-type biogenesis protein
FORC8_1057	ENOG4107QX9	Thiol disulfide interChange protein
FORC8_1058	ENOG4108DMF	Cytochrome C biogenesis protein
FORC8_1060	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
FORC8_1065	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
FORC8_1066	ENOG4105EAQ	(twin-arginine translocation) pathway signal
FORC8_1067	ENOG4105C5X	domain protein
FORC8_1070	ENOG4105CH5	extracellular solute-binding protein, family 7
FORC8_1072	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FORC8_1075	ENOG41067TZ	transcriptional regulator, MarR family
FORC8_1076	ENOG4105C94	Transporter
FORC8_1077	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_1081	ENOG4105CGF	Aromatic amino acid aminotransferase
FORC8_1084	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FORC8_1086	ENOG4105C5S	asparaginyl-tRNA synthetase
FORC8_1087	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_1088	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
FORC8_1090	ENOG4105BZU	Histidine kinase
FORC8_1091	ENOG4105EJQ	L-serine dehydratase
FORC8_1092	ENOG4105C44	Serine transporter
FORC8_1095	ENOG4105BZU	Histidine kinase
FORC8_1096	ENOG4105CRQ	synthase (Component I)
FORC8_1099	ENOG4105CM6	amino acid regulated cytosolic protein
FORC8_1100	ENOG4106K28	UPF0283 membrane protein
FORC8_1102	ENOG4105D9U	N-acetyltransferase
FORC8_1109	ENOG4105K8R	UPF0145 protein
FORC8_1129	ENOG4105K5X	acetyltransferase
FORC8_1136	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FORC8_1147	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FORC8_1149	ENOG4105EWC	Purine nucleoside phosphorylase
FORC8_1174	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
FORC8_1175	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FORC8_1191	ENOG4105C4R	Atp-dependent dna helicase
FORC8_1214	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
FORC8_1221	ENOG4105EWC	Purine nucleoside phosphorylase
FORC8_1241	ENOG4108J1Q	
FORC8_1247	ENOG4107S6Z	Na H antiporter
FORC8_1248	ENOG4105CFQ	glutamine synthetase
FORC8_1249	ENOG4108Z86	Glutamine amidotransferase
FORC8_1250	ENOG4107VRI	Transcriptional regulator
FORC8_1251	ENOG4105C26	Dehydrogenase
FORC8_1252	ENOG4105CJP	fad dependent oxidoreductase
FORC8_1254	ENOG4105DWY	Agmatine deiminase
FORC8_1255	ENOG4105C26	Dehydrogenase
FORC8_1256	ENOG4108JPW	Aminotransferase
FORC8_1257	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
FORC8_1258	ENOG4105BZU	Histidine kinase
FORC8_1261	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FORC8_1262	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
FORC8_1264	ENOG4108ZT1	Transcriptional regulator
FORC8_1265	ENOG4105MSB	protein, conserved in bacteria
FORC8_1269	ENOG4108UW5	maltose o-acetyltransferase
FORC8_1272	ENOG4105BZU	Histidine kinase
FORC8_1273	ENOG4105BZU	Histidine kinase
FORC8_1275	ENOG41090FY	type IV pilus biogenesis stability protein PilW
FORC8_1276	ENOG4105CVG	Homoserine O-transsuccinylase
FORC8_1278	ENOG4105E5D	amino acid
FORC8_1279	ENOG4105D1S	lipid A biosynthesis
FORC8_1280	ENOG4105CTD	carboxy-peptidase
FORC8_1281	ENOG410829K	Lysine exporter protein (Lyse ygga)
FORC8_1283	ENOG4105BZG	amino acid carrier protein
FORC8_1288	ENOG4105E0M	Sulfatase
FORC8_1289	ENOG4105DHQ	Histidine kinase
FORC8_1296	ENOG4105GIJ	Glycine betaine
FORC8_1297	ENOG4108HQS	Glycine betaine
FORC8_1298	ENOG4108IJ7	Glycine betaine
FORC8_1301	ENOG4105C94	Transporter
FORC8_1302	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
FORC8_1303	ENOG4108JPW	Aminotransferase
FORC8_1304	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
FORC8_1305	ENOG4105CZK	Aspartate kinase
FORC8_1306	ENOG4105CA0	peroxidase
FORC8_1309	ENOG4107V40	secretion protein, HlyD family
FORC8_1312	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
FORC8_1313	ENOG4108V9W	transcriptional regulatory protein
FORC8_1314	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
FORC8_1315	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
FORC8_1316	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
FORC8_1319	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
FORC8_1320	ENOG4105C26	Dehydrogenase
FORC8_1324	ENOG4108KB1	transcriptional regulator, arac family
FORC8_1330	ENOG41066XE	Type III export protein
FORC8_1344	ENOG4105ENX	hydrolase
FORC8_1345	ENOG4105ENX	hydrolase
FORC8_1346	ENOG4105EQ2	LysR family Transcriptional regulator
FORC8_1368	ENOG4105EJ9	Membrane
FORC8_1374	ENOG4105CR4	methylisocitrate lyase
FORC8_1375	ENOG4105BZN	citrate synthase
FORC8_1376	ENOG4108I0Z	Aconitate hydratase
FORC8_1377	ENOG4105C7F	AcnD-accessory protein PrpF
FORC8_1378	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FORC8_1382	ENOG410667J	hydrolase
FORC8_1383	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FORC8_1384	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
FORC8_1385	ENOG4105BZU	Histidine kinase
FORC8_1387	ENOG4105CDV	Ompa motb domain protein
FORC8_1390	ENOG4105CDV	Ompa motb domain protein
FORC8_1393	ENOG4105DR4	Methyltransferase
FORC8_1394	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_1395	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
FORC8_1396	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
FORC8_1398	ENOG4108MN8	Membrane
FORC8_1399	ENOG4105CDA	abc transporter atp-binding protein
FORC8_1400	ENOG4105DRP	amino acid AbC transporter
FORC8_1401	ENOG4105EZ7	amino acid ABC transporter
FORC8_1402	ENOG4107QXX	ABC transporter
FORC8_1404	ENOG4108VPT	UPF0234 protein
FORC8_1405	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FORC8_1409	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FORC8_1410	ENOG4105DY2	Paraquat-inducible protein b
FORC8_1411	ENOG4105H2K	paraquat-inducible protein a
FORC8_1412	ENOG4105BZ1	(ABC) transporter
FORC8_1413	ENOG4108ZGC	gaf domain protein
FORC8_1414	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
FORC8_1415	ENOG4105CN1	protease
FORC8_1417	ENOG4105CD8	aminopeptidase N
FORC8_1418	ENOG4105C7I	Dehydrogenase
FORC8_1419	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FORC8_1420	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
FORC8_1421	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FORC8_1423	ENOG4105C5H	ABC transporter
FORC8_1426	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
FORC8_1427	ENOG4105DAN	ATP-dependent protease
FORC8_1428	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
FORC8_1451	ENOG4108MIB	
FORC8_1453	ENOG4105BZU	Histidine kinase
FORC8_1456	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
FORC8_1459	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
FORC8_1461	ENOG4105C59	p-type ATPase
FORC8_1464	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FORC8_1465	ENOG4105Q9Y	Universal stress protein
FORC8_1468	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
FORC8_1472	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FORC8_1473	ENOG4105F38	ABC transporter, permease
FORC8_1474	ENOG4105D38	putrescine abc transporter
FORC8_1475	ENOG4107RUE	extracellular solute-binding protein family 1
FORC8_1476	ENOG4107RUE	extracellular solute-binding protein family 1
FORC8_1477	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FORC8_1489	ENOG4105QAX	Iron-sulfur
FORC8_1490	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FORC8_1492	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
FORC8_1496	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
FORC8_1497	ENOG4105C5H	ABC transporter
FORC8_1498	ENOG4105BZU	Histidine kinase
FORC8_1499	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_1502	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FORC8_1503	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FORC8_1504	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FORC8_1506	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
FORC8_1507	ENOG4106IUH	DTW domain containing protein
FORC8_1514	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_1515	ENOG4107TT5	NLP P60 protein
FORC8_1517	ENOG4105BZU	Histidine kinase
FORC8_1518	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FORC8_1519	ENOG4105FGM	Fructosamine kinase
FORC8_1521	ENOG4108R6K	riboflavin synthase, subunit alpha
FORC8_1522	ENOG4107QI1	Mate efflux family protein
FORC8_1525	ENOG41082AN	stage II sporulation protein
FORC8_1527	ENOG4107V1M	polysaccharide export protein
FORC8_1530	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_1532	ENOG4107TYR	Glycosyl Transferase
FORC8_1538	ENOG4105CPK	Glycosyl transferase (Group 1
FORC8_1539	ENOG4105CND	Glycosyl transferase, family 2
FORC8_1542	ENOG4105C94	Transporter
FORC8_1545	ENOG4105CQ7	ATP-dependent helicase
FORC8_1546	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
FORC8_1547	ENOG4105N1P	Ferredoxin-type protein
FORC8_1548	ENOG4108NEM	leader-binding protein dmsD
FORC8_1549	ENOG4107KGK	dmso reductase anchor subunit
FORC8_1550	ENOG4105QAX	Iron-sulfur
FORC8_1551	ENOG4107QY8	reductase
FORC8_1557	ENOG4105BZU	Histidine kinase
FORC8_1559	ENOG4105CFG	Acts as a chaperone (By similarity)
FORC8_1560	ENOG4105CFG	Acts as a chaperone (By similarity)
FORC8_1565	ENOG4105BZ1	(ABC) transporter
FORC8_1566	ENOG4105BZ1	(ABC) transporter
FORC8_1570	ENOG4105E0U	tyrosine-specific transport protein
FORC8_1572	ENOG4105DHT	Metal Dependent Phosphohydrolase
FORC8_1586	ENOG4105EW9	transcriptional regulator AsnC family
FORC8_1593	ENOG4105D9P	serine threonine protein kinase
FORC8_1598	ENOG4105CS6	Rhs element vgr protein
FORC8_1599	ENOG4108WC9	type VI secretion system effector, hcp1 family
FORC8_1600	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FORC8_1601	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_1606	ENOG4105DR5	peptidase
FORC8_1607	ENOG4105EE5	Membrane protein terC
FORC8_1609	ENOG41076CZ	activating enzyme
FORC8_1610	ENOG4105G0K	glycine radical enzyme YjjI family
FORC8_1612	ENOG4105CPI	Metal Dependent Phosphohydrolase
FORC8_1613	ENOG4105BZU	Histidine kinase
FORC8_1614	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_1615	ENOG4105BZU	Histidine kinase
FORC8_1616	ENOG4105C8P	)-transporter
FORC8_1623	ENOG4105DUM	transcriptional regulator, lysR family
FORC8_1627	ENOG4105Y49	secretion protein, HlyD family
FORC8_1634	ENOG4108RXX	maleylacetoacetate isomerase
FORC8_1636	ENOG4105F1J	Homogentisate 1,2-dioxygenase
FORC8_1637	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
FORC8_1639	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FORC8_1640	ENOG4107QSI	ABC, transporter
FORC8_1641	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FORC8_1642	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FORC8_1643	ENOG4105C3U	ABC transporter
FORC8_1644	ENOG4108JQ7	(ABC) transporter
FORC8_1646	ENOG4107MM9	BNR Asp-box repeat-containing protein
FORC8_1648	ENOG4105D38	putrescine abc transporter
FORC8_1649	ENOG4105F38	ABC transporter, permease
FORC8_1650	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FORC8_1651	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FORC8_1652	ENOG4105CIF	Ornithine Cyclodeaminase
FORC8_1655	ENOG4105CTU	Proline racemase
FORC8_1661	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
FORC8_1662	ENOG4108VKG	metal-dependent hydrolase
FORC8_1663	ENOG4105KPE	licD family
FORC8_1665	ENOG4107XDJ	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
FORC8_1669	ENOG4107RSM	transcriptional regulator
FORC8_1673	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
FORC8_1674	ENOG4108IU2	vtamin B12-transporter permease
FORC8_1675	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
FORC8_1680	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
FORC8_1681	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
FORC8_1682	ENOG4105K4T	epimerase
FORC8_1683	ENOG4108ETY	sodium dicarboxylate symporter
FORC8_1684	ENOG4105CJB	Exodeoxyribonuclease I
FORC8_1685	ENOG4105VAW	lrga family
FORC8_1686	ENOG41067MG	lrgb family
FORC8_1687	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
FORC8_1688	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
FORC8_1689	ENOG4105FQ6	thiopurine methyltransferase
FORC8_1691	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FORC8_1693	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FORC8_1694	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FORC8_1695	ENOG4105BZU	Histidine kinase
FORC8_1701	ENOG4105K8R	UPF0145 protein
FORC8_1702	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FORC8_1703	ENOG41082NX	50s ribosomal protein l35
FORC8_1704	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FORC8_1705	ENOG4105C22	threonyL-tRNA synthetase
FORC8_1708	ENOG4105CZE	histidine utilization repressor
FORC8_1709	ENOG4105CI2	imidazolone-5-propionate hydrolase
FORC8_1710	ENOG41088SP	formiminoglutamate hydrolase
FORC8_1712	ENOG4105C84	Histidine ammonia-lyase
FORC8_1715	ENOG4105CQB	FAD linked oxidase domain protein
FORC8_1718	ENOG4105CDV	Ompa motb domain protein
FORC8_1722	ENOG4105C8V	SAICAR synthetase
FORC8_1725	ENOG4105HDD	phospholipase
FORC8_1726	ENOG4105CQ7	ATP-dependent helicase
FORC8_1727	ENOG4107R1I	NAD-dependent malic enzyme
FORC8_1728	ENOG4107GZ4	SanA protein
FORC8_1729	ENOG4105C8P	)-transporter
FORC8_1730	ENOG4105BZU	Histidine kinase
FORC8_1732	ENOG4105C9B	Cysteine desulfurase
FORC8_1734	ENOG4105C3M	thioredoxin reductase
FORC8_1735	ENOG4108JJ9	ABC, transporter
FORC8_1736	ENOG4108JJ8	(ABC) transporter
FORC8_1737	ENOG4105BZC	d-serine deaminase
FORC8_1738	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FORC8_1740	ENOG4105BZU	Histidine kinase
FORC8_1746	ENOG4105DWU	Membrane
FORC8_1748	ENOG4105DY8	decarboxylase
FORC8_1749	ENOG4106KNT	transcriptional regulator
FORC8_1751	ENOG41090BQ	Glutaredoxin
FORC8_1752	ENOG4105D0C	transport protein
FORC8_1755	ENOG4105RKW	reductase (By
FORC8_1756	ENOG4107QPN	acyl-Coa dehydrogenase
FORC8_1757	ENOG41067SE	Tetr family transcriptional regulator
FORC8_1758	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FORC8_1761	ENOG4108I0Y	(ABC) transporter
FORC8_1762	ENOG4107QI1	Mate efflux family protein
FORC8_1763	ENOG4105CGD	Nad-dependent epimerase dehydratase
FORC8_1764	ENOG4105CUW	cytochrome C-TYPE protein
FORC8_1770	ENOG4105C2C	drug resistance transporter, Bcr CflA
FORC8_1771	ENOG4105I08	Pseudouridine synthase
FORC8_1772	ENOG4105CFI	type iii restriction protein res subunit
FORC8_1774	ENOG4105ETX	regulatoR
FORC8_1775	ENOG4105EB3	Histidine kinase
FORC8_1776	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FORC8_1779	ENOG4105CGH	5'-nucleotidase
FORC8_1781	ENOG4105XZD	Fe-S protein
FORC8_1783	ENOG4108ZXC	Two component transcriptional regulator, luxr family
FORC8_1784	ENOG4106AFQ	Histidine kinase
FORC8_1786	ENOG4105BZ8	glutamate synthase
FORC8_1788	ENOG4108RSN	SNARE associated Golgi
FORC8_1789	ENOG4105VNH	ABC transporter solute-binding protein
FORC8_1790	ENOG4105CXZ	ABC transporter, permease
FORC8_1791	ENOG4108VGW	abc transporter atp-binding protein
FORC8_1792	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
FORC8_1794	ENOG4108JUA	Transcriptional regulator
FORC8_1795	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
FORC8_1796	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FORC8_1798	ENOG4108W1A	pseudouridine synthase
FORC8_1800	ENOG4105C8J	)-transporter
FORC8_1801	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FORC8_1802	ENOG4105C28	cystathionine
FORC8_1803	ENOG4107IFA	Lipase (EC 3.1.1.3)
FORC8_1805	ENOG4108R3E	Dna-3-methyladenine glycosylase i
FORC8_1808	ENOG410624X	efflux transporter, rnd family, mfp subunit
FORC8_1809	ENOG4105FM1	phage shock protein C
FORC8_1810	ENOG4105YYT	phage shock protein B
FORC8_1811	ENOG41087YS	Phage shock protein A
FORC8_1812	ENOG4105E51	psp operon transcriptional activator
FORC8_1813	ENOG4108J59	Extracellular solute-binding protein, family 5
FORC8_1814	ENOG4108I5W	peptide transport system, permease protein
FORC8_1815	ENOG4108EU3	peptide transport system, permease
FORC8_1816	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
FORC8_1817	ENOG4108JQ2	peptide transport system atp-binding protein
FORC8_1819	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
FORC8_1822	ENOG4108J2R	molybdopterin oxidoreductase
FORC8_1825	ENOG4105C4B	ABC transporter, permease
FORC8_1826	ENOG4105TMB	Formate nitrite transporter
FORC8_1831	ENOG4105GFG	DUF218 domain
FORC8_1832	ENOG4107104	thymidine kinase
FORC8_1833	ENOG4105C8N	cysteinyl-tRNA synthetase
FORC8_1834	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FORC8_1835	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
FORC8_1836	ENOG4105D58	Diguanylate phosphodiesterase
FORC8_1837	ENOG4105K5B	UPF0225 protein
FORC8_1838	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FORC8_1839	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FORC8_1841	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FORC8_1842	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FORC8_1843	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FORC8_1844	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FORC8_1845	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FORC8_1846	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_1848	ENOG4107S6Z	Na H antiporter
FORC8_1849	ENOG4108YX2	DNA-binding protein
FORC8_1850	ENOG4107RE1	Inosine-guanosine kinase
FORC8_1852	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FORC8_1853	ENOG41075W9	High frequency lysogenization protein HflD homolog
FORC8_1854	ENOG4107QTF	adenylosuccinate lyase
FORC8_1858	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FORC8_1861	ENOG4107FW0	short-chain dehydrogenase reductase
FORC8_1863	ENOG4105D0M	Protease HtpX homolog
FORC8_1865	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
FORC8_1867	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FORC8_1868	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FORC8_1869	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FORC8_1870	ENOG4105KSC	Transcriptional regulator, TraR DksA family
FORC8_1873	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FORC8_1874	ENOG4105D1H	recombination factor protein RarA
FORC8_1875	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
FORC8_1876	ENOG4105CNU	cell division protein FtsK
FORC8_1877	ENOG4105EW9	transcriptional regulator AsnC family
FORC8_1878	ENOG4105DCF	alanine dehydrogenase
FORC8_1880	ENOG4107R11	Transcriptional regulator
FORC8_1882	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
FORC8_1888	ENOG4105BZS	acriflavin resistance protein
FORC8_1889	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FORC8_1890	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_1899	ENOG4108RNS	Exports L-alanine (By similarity)
FORC8_1900	ENOG4105BZU	Histidine kinase
FORC8_1902	ENOG4106032	Glutathionylspermidine synthase
FORC8_1904	ENOG4105Z6B	inner membrane protein yjfl
FORC8_1906	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
FORC8_1907	ENOG4105UFD	tol-pal system protein YbgF
FORC8_1908	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FORC8_1909	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FORC8_1911	ENOG4105M8F	Biopolymer transport protein exbD tolR
FORC8_1912	ENOG4105E02	MotA TolQ exbB proton channel
FORC8_1913	ENOG4107YD3	Thioesterase
FORC8_1915	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FORC8_1916	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FORC8_1917	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FORC8_1918	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FORC8_1919	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_1920	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FORC8_1921	ENOG4105C9M	aspartyl-trna synthetase
FORC8_1922	ENOG41081XQ	Conserved Protein
FORC8_1923	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
FORC8_1924	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
FORC8_1925	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FORC8_1927	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FORC8_1929	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
FORC8_1930	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
FORC8_1931	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
FORC8_1932	ENOG4106371	Methyltransferase
FORC8_1933	ENOG4107S90	membrAne
FORC8_1934	ENOG4106WF9	DNA-binding transcriptional regulator TorR
FORC8_1935	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
FORC8_1936	ENOG4105ETE	Transcriptional regulator (LacI family
FORC8_1937	ENOG4105HP8	regulator of competence-specific genes
FORC8_1941	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FORC8_1942	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FORC8_1943	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
FORC8_1944	ENOG4105RKX	Protein of unknown function (DUF2498)
FORC8_1945	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FORC8_1947	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FORC8_1948	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
FORC8_1949	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FORC8_1951	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FORC8_1952	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FORC8_1953	ENOG4105VEQ	Cold shock protein
FORC8_1955	ENOG4108R99	pseudouridine synthase
FORC8_1958	ENOG4105DVT	helicase
FORC8_1959	ENOG4105EJ9	Membrane
FORC8_1960	ENOG4108URS	primosomal replication protein n''
FORC8_1961	ENOG4106428	Protein of unknown function (DUF2496)
FORC8_1962	ENOG4105CGK	Exodeoxyribonuclease III
FORC8_1965	ENOG4105DSP	amino acid AbC transporter
FORC8_1966	ENOG4105E89	ABC transporter
FORC8_1967	ENOG4108JEH	abc transporter atp-binding protein
FORC8_1970	ENOG4105C6N	Formate acetyltransferase
FORC8_1972	ENOG4105F1A	Pyruvate formate-lyase
FORC8_1974	ENOG4105XWI	UPF0304 protein
FORC8_1975	ENOG4105CYN	Serine protein kinase
FORC8_1976	ENOG4106AKX	UPF0229 protein
FORC8_1977	ENOG4105ED1	spovr family
FORC8_1978	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FORC8_1979	ENOG4105W49	UPF0434 protein
FORC8_1980	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FORC8_1981	ENOG4105BZ1	(ABC) transporter
FORC8_1982	ENOG4108EC8	DNA internalization-related competence protein ComEC
FORC8_1983	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
FORC8_1985	ENOG4105D60	lipoprotein releasing system transmembrane protein
FORC8_1986	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FORC8_1987	ENOG4105D60	lipoprotein releasing system transmembrane protein
FORC8_1989	ENOG4108JA2	transcriptioN-repair coupling factor
FORC8_1992	ENOG4105CEP	NADH dehydrogenase
FORC8_1993	ENOG4105D0Y	UPF0227 protein
FORC8_1998	ENOG4105K59	histidine triad (HIT) protein
FORC8_1999	ENOG4108NVR	Methyl-accepting chemotaxis
FORC8_2001	ENOG4107SXA	Phosphorylase
FORC8_2003	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FORC8_2004	ENOG4105DZ0	fad dependent oxidoreductase
FORC8_2005	ENOG4108Z4U	Ferredoxin
FORC8_2007	ENOG4108KHX	Diguanylate cyclase
FORC8_2010	ENOG4108MNP	Glycoprotein polysaccharide metabolism
FORC8_2011	ENOG4105C29	acyl-CoA thioesterase
FORC8_2013	ENOG4108XM1	transcriptional regulator AsnC family
FORC8_2018	ENOG4105BZS	acriflavin resistance protein
FORC8_2022	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
FORC8_2023	ENOG4105HMI	Membrane
FORC8_2025	ENOG4105CEY	Amp-dependent synthetase and ligase
FORC8_2026	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
FORC8_2027	ENOG4108IPT	Naphthoate synthase
FORC8_2028	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
FORC8_2029	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
FORC8_2030	ENOG4105E4F	Isochorismate synthase
FORC8_2031	ENOG4105CHM	Aminotransferase
FORC8_2032	ENOG4105DK2	UPF0207 protein
FORC8_2033	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FORC8_2036	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
FORC8_2037	ENOG4105EIN	peptidylprolyl cis-trans isomerase
FORC8_2038	ENOG4105K70	DNA-binding protein
FORC8_2039	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FORC8_2040	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FORC8_2041	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FORC8_2042	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FORC8_2044	ENOG4105CQZ	Histidine kinase
FORC8_2047	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FORC8_2048	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
FORC8_2049	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
FORC8_2050	ENOG4105CNG	UPF0061 protein
FORC8_2054	ENOG4107ZYR	domain protein
FORC8_2055	ENOG4105C1J	atp-dependent rna helicase
FORC8_2063	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FORC8_2067	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FORC8_2068	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
FORC8_2069	ENOG4105C84	Histidine ammonia-lyase
FORC8_2074	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FORC8_2075	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FORC8_2076	ENOG4105C2D	reductase
FORC8_2077	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FORC8_2079	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FORC8_2080	ENOG4105D9N	nucleoside
FORC8_2081	ENOG4105CC0	LysR family Transcriptional regulator
FORC8_2082	ENOG4105CVE	Lytic murein transglycosylase
FORC8_2083	ENOG4105VNG	YcgL domain-containing protein
FORC8_2084	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
FORC8_2085	ENOG4107QMS	site-determining protein
FORC8_2086	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
FORC8_2087	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
FORC8_2088	ENOG4105CEY	Amp-dependent synthetase and ligase
FORC8_2089	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
FORC8_2092	ENOG41072GX	Peptidase M22 Glycoprotease
FORC8_2093	ENOG4105DVT	helicase
FORC8_2094	ENOG4105CIY	formyltetrahydrofolate deformylase
FORC8_2095	ENOG4106ZCM	YecM protein
FORC8_2096	ENOG4105C75	arginyL-tRNA synthetase
FORC8_2099	ENOG4105CE1	Ferrous iron transport protein b
FORC8_2100	ENOG4105XFK	Ferrous iron transport protein A
FORC8_2101	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
FORC8_2102	ENOG4105NXV	High-affinity zinc uptake system protein
FORC8_2103	ENOG4105FDK	ABC transporter
FORC8_2104	ENOG4105FAV	ABC, transporter
FORC8_2105	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FORC8_2106	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FORC8_2107	ENOG4105C7S	Dehydrogenase
FORC8_2108	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
FORC8_2109	ENOG4105E33	succinate dehydrogenase
FORC8_2110	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
FORC8_2111	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
FORC8_2112	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
FORC8_2113	ENOG4105BZN	citrate synthase
FORC8_2114	ENOG4107QNR	UPF0135 protein
FORC8_2116	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
FORC8_2117	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
FORC8_2118	ENOG4105EV9	Alpha Beta Hydrolase
FORC8_2120	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
FORC8_2121	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FORC8_2122	ENOG41090R7	Ferric uptake
FORC8_2123	ENOG4105CX6	glutaminyL-tRNA synthetase
FORC8_2125	ENOG4105CE4	GlcNAc 6-P deacetylase
FORC8_2126	ENOG4105E2R	ROK family
FORC8_2127	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FORC8_2128	ENOG4105CAQ	asparagine synthetase
FORC8_2129	ENOG4105MDZ	Transcriptional activator rfaH
FORC8_2130	ENOG4105DUX	Transporter
FORC8_2131	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FORC8_2132	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FORC8_2133	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FORC8_2134	ENOG4108DQ1	activator toxR
FORC8_2138	ENOG4108RE9	Phosphodiesterase
FORC8_2143	ENOG4105ECP	epimerase
FORC8_2144	ENOG4105E1F	short-chain dehydrogenase reductase
FORC8_2145	ENOG4107QR8	Thioredoxin
FORC8_2146	ENOG4107QX8	SPFH domain, Band 7 family protein
FORC8_2150	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FORC8_2151	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
FORC8_2152	ENOG4105EXN	Sulfate transport protein CysZ
FORC8_2153	ENOG4105C6T	cysteine synthase
FORC8_2154	ENOG4105KZ7	phosphocarrier protein hpr
FORC8_2155	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FORC8_2156	ENOG4105C5Y	PTS System
FORC8_2158	ENOG4105I03	Flagellin
FORC8_2159	ENOG4105I03	Flagellin
FORC8_2160	ENOG4105DTJ	flagellar hook-associated protein
FORC8_2162	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
FORC8_2163	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FORC8_2164	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FORC8_2165	ENOG4105CGA	flagellar basal-body rod protein FlgG
FORC8_2166	ENOG4108KPB	Flagellar basal-body rod protein FlgF
FORC8_2167	ENOG4105BZE	flagellar hook protein, FlgE
FORC8_2168	ENOG4105W00	Flagellar hook capping protein
FORC8_2169	ENOG4108ZC9	flagellar basal-body rod protein flgc
FORC8_2170	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
FORC8_2171	ENOG4105BZU	Histidine kinase
FORC8_2172	ENOG4107R88	Chemotaxis protein (CheV)
FORC8_2180	ENOG4105UYK	outer membrane protein a
FORC8_2181	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FORC8_2183	ENOG41081QG	Porin Gram-negative type
FORC8_2184	ENOG4105C59	p-type ATPase
FORC8_2187	ENOG4105E2D	ec 3.2.1.52
FORC8_2189	ENOG4108DG9	Smr protein MutS2
FORC8_2190	ENOG4105FE9	pseudouridine synthase
FORC8_2191	ENOG4108Z66	YbaK ebsC protein
FORC8_2192	ENOG4105CGH	5'-nucleotidase
FORC8_2193	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FORC8_2194	ENOG41063JG	Transcriptional regulator
FORC8_2195	ENOG4108YY7	Invasion gene expression up-regulator SirB
FORC8_2196	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FORC8_2197	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FORC8_2198	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FORC8_2199	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
FORC8_2200	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FORC8_2201	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FORC8_2202	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FORC8_2203	ENOG4105C3G	gtp-binding protein
FORC8_2205	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
FORC8_2206	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FORC8_2207	ENOG4105C9A	Phoh family
FORC8_2208	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FORC8_2209	ENOG4108JU5	Magnesium and cobalt efflux protein
FORC8_2210	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FORC8_2211	ENOG4107PAI	alpha helical protein
FORC8_2212	ENOG4105C8T	Leucyl-tRNA synthetase
FORC8_2213	ENOG4108U2H	Rare lipoprotein B
FORC8_2214	ENOG4105DJF	DNA polymerase III, delta' subunit
FORC8_2215	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
FORC8_2216	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FORC8_2217	ENOG4105CJN	penicillin-binding protein
FORC8_2218	ENOG4105CNI	cell division protein FtsW
FORC8_2219	ENOG4105K6T	rare lipoprotein A
FORC8_2220	ENOG4105DZ1	carboxypeptidase
FORC8_2221	ENOG4108Z43	UPF0250 protein
FORC8_2222	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FORC8_2223	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FORC8_2224	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FORC8_2225	ENOG4108JYZ	YitT family
FORC8_2228	ENOG4105CG3	alpha amylase, catalytic region
FORC8_2229	ENOG4105C5Y	PTS System
FORC8_2230	ENOG4105D4X	repressor
FORC8_2231	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
FORC8_2232	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
FORC8_2233	ENOG4108UMI	ABC transporter, permease
FORC8_2234	ENOG4105D01	(LipO)protein
FORC8_2235	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
FORC8_2236	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
FORC8_2237	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FORC8_2239	ENOG4105BZU	Histidine kinase
FORC8_2240	ENOG4105EWT	decarboxylase family
FORC8_2241	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
FORC8_2243	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
FORC8_2244	ENOG4105M08	Membrane
FORC8_2246	ENOG4105ETT	transcriptional Regulator, LysR family
FORC8_2247	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
FORC8_2248	ENOG4107QKZ	Ompa motb domain protein
FORC8_2249	ENOG4105E14	MotA TolQ exbB proton channel
FORC8_2250	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FORC8_2251	ENOG4105CTB	Polyprenyl synthetase
FORC8_2252	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FORC8_2253	ENOG4108ZAI	phosphatidylglycerophosphatase a
FORC8_2254	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FORC8_2255	ENOG4107YIM	Involved in the transcription termination process (By similarity)
FORC8_2256	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FORC8_2259	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FORC8_2260	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FORC8_2261	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FORC8_2262	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FORC8_2263	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
FORC8_2264	ENOG4108DJV	Fermentation respiration switch protein
FORC8_2265	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
FORC8_2266	ENOG4105C7N	Xanthine uracil vitamin C permease
FORC8_2267	ENOG4105CIN	aminoacyl-histidine dipeptidase
FORC8_2272	ENOG4108ETH	Formylglycinamide ribotide synthetase
FORC8_2273	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
FORC8_2274	ENOG4108Z6B	deaminase
FORC8_2275	ENOG4105CFC	Transporter
FORC8_2281	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FORC8_2282	ENOG4105CFG	Acts as a chaperone (By similarity)
FORC8_2284	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC8_2285	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FORC8_2287	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FORC8_2288	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FORC8_2289	ENOG4105VDB	UPF0125 protein
FORC8_2290	ENOG4108Z1B	Cyclase dehydrase
FORC8_2291	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FORC8_2292	ENOG4105DFP	Integrase
FORC8_2297	ENOG4107XZC	Restriction modification system DNA (Specificity
FORC8_2298	ENOG4105DZR	Type I site-specific deoxyribonuclease
FORC8_2300	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
FORC8_2312	ENOG4105ETT	transcriptional Regulator, LysR family
FORC8_2313	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FORC8_2317	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FORC8_2318	ENOG4108IQK	o-acetylhomoserine
FORC8_2323	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
FORC8_2324	ENOG4105BZG	amino acid carrier protein
FORC8_2326	ENOG4106HK8	GPR1 FUN34 yaaH family protein
FORC8_2328	ENOG4107S6Z	Na H antiporter
FORC8_2329	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FORC8_2330	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FORC8_2331	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FORC8_2334	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FORC8_2335	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FORC8_2336	ENOG4105N21	Membrane
FORC8_2337	ENOG4105CUT	histidyl-tRNA synthetase
FORC8_2338	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FORC8_2340	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FORC8_2341	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FORC8_2342	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FORC8_2343	ENOG4105WVQ	Fe-S assembly protein IscX
FORC8_2344	ENOG4108ZIT	Ferredoxin, 2FE-2S
FORC8_2345	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
FORC8_2346	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
FORC8_2347	ENOG4108Z4V	iron-sulfur cluster assembly
FORC8_2348	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
FORC8_2349	ENOG4105C3J	Cysteine desulfurase
FORC8_2350	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
FORC8_2351	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
FORC8_2352	ENOG4105ECY	inositol monophosphatase
FORC8_2353	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FORC8_2354	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FORC8_2355	ENOG4105VIE	preprotein translocase, subunit YajC
FORC8_2356	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FORC8_2357	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FORC8_2359	ENOG4105W87	Cbs domain
FORC8_2360	ENOG4108I9X	Isocitrate lyase
FORC8_2361	ENOG4107QP3	malate synthase g
FORC8_2362	ENOG4105C5Q	Transcriptional regulator
FORC8_2363	ENOG4105D3R	alkyl hydroperoxide reductase
FORC8_2364	ENOG4106N3A	copper homeostasis protein cutc
FORC8_2365	ENOG4105CSR	polyphosphate kinase 2
FORC8_2367	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FORC8_2368	ENOG4105E2Z	phosphate ABC transporter (Permease
FORC8_2369	ENOG4105C8U	phosphate abc transporter
FORC8_2370	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FORC8_2371	ENOG4105C9X	ppx gppa phosphatase
FORC8_2373	ENOG4105BZU	Histidine kinase
FORC8_2374	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FORC8_2375	ENOG4105DH7	May be involved in recombination (By similarity)
FORC8_2376	ENOG4105CFP	Peptidase U32
FORC8_2377	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
FORC8_2381	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FORC8_2382	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
FORC8_2383	ENOG4105C34	Pseudouridine synthase
FORC8_2384	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC8_2385	ENOG4105E4C	Lytic transglycosylase catalytic
FORC8_2386	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
FORC8_2388	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FORC8_2389	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
FORC8_2390	ENOG4107SC1	transglycosylase
FORC8_2391	ENOG4105C5H	ABC transporter
FORC8_2394	ENOG4105DR5	peptidase
FORC8_2395	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
FORC8_2396	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FORC8_2397	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
FORC8_2398	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
FORC8_2399	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC8_2403	ENOG4108HRK	Histidine kinase
FORC8_2404	ENOG4108NEV	two component transcriptional regulator, LytTR family
FORC8_2405	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FORC8_2406	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
FORC8_2407	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FORC8_2408	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FORC8_2409	ENOG4105DTN	riboflavin biosynthesis protein ribF
FORC8_2410	ENOG4105CJR	Integral membrane protein (MviN
FORC8_2411	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
FORC8_2412	ENOG41080HT	Transcriptional regulator, arsr family
FORC8_2413	ENOG41063Z6	transcriptional regulator, lysR family
FORC8_2416	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
FORC8_2417	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FORC8_2418	ENOG4105HF0	Membrane
FORC8_2419	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
FORC8_2420	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FORC8_2422	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
FORC8_2424	ENOG4105CPC	Aldo Keto reductase
FORC8_2426	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_2427	ENOG4105CRK	lysyL-tRNA synthetase
FORC8_2428	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
FORC8_2429	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FORC8_2430	ENOG4105T95	Thiol disulfide interChange protein
FORC8_2431	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FORC8_2432	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
FORC8_2433	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
FORC8_2434	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
FORC8_2435	ENOG4105C1J	atp-dependent rna helicase
FORC8_2436	ENOG4105D1Q	UPF0246 protein
FORC8_2437	ENOG4105BZG	amino acid carrier protein
FORC8_2440	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FORC8_2441	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
FORC8_2442	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
FORC8_2443	ENOG4105D98	threonine synthase
FORC8_2444	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FORC8_2447	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
FORC8_2449	ENOG41065U4	response regulator
FORC8_2451	ENOG4105BZU	Histidine kinase
FORC8_2453	ENOG4105N5T	Radical SAM Protein
FORC8_2456	ENOG4105CBC	glutamate synthase
FORC8_2457	ENOG4105BZ8	glutamate synthase
FORC8_2459	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
FORC8_2460	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
FORC8_2461	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
FORC8_2462	ENOG4105EN6	Membrane
FORC8_2463	ENOG4105VP0	transcriptional regulator, lysR family
FORC8_2464	ENOG4105EJ9	Membrane
FORC8_2467	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FORC8_2468	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FORC8_2469	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FORC8_2470	ENOG4105M6F	mutator MutT protein
FORC8_2471	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FORC8_2472	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FORC8_2473	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FORC8_2474	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FORC8_2475	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
FORC8_2476	ENOG4105DFU	Cell wall formation (By similarity)
FORC8_2477	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FORC8_2479	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FORC8_2480	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FORC8_2481	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
FORC8_2482	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FORC8_2483	ENOG4105CJN	penicillin-binding protein
FORC8_2484	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
FORC8_2485	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FORC8_2486	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FORC8_2488	ENOG41082RQ	UPF0102 protein
FORC8_2489	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
FORC8_2490	ENOG4105W4M	Transport-associated protein
FORC8_2491	ENOG4105KB2	stringent starvation protein b
FORC8_2492	ENOG4107MKT	Stringent starvation protein a
FORC8_2493	ENOG4105EIX	cytochrome c1
FORC8_2494	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FORC8_2495	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FORC8_2496	ENOG4108UJD	30S ribosomal protein S9
FORC8_2497	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FORC8_2498	ENOG4105D6Z	AFG1 family ATPase
FORC8_2499	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
FORC8_2500	ENOG4105C0H	protease
FORC8_2501	ENOG4105C0H	protease
FORC8_2502	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FORC8_2503	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FORC8_2504	ENOG4105IPS	esterase
FORC8_2505	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
FORC8_2506	ENOG4108SX3	cytoplasmic protein
FORC8_2507	ENOG41087AY	ADP-Ribose pyrophosphatase
FORC8_2508	ENOG4105DFG	type I secretion outer membrane protein
FORC8_2509	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
FORC8_2510	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
FORC8_2511	ENOG4108NVR	Methyl-accepting chemotaxis
FORC8_2513	ENOG4105I7R	Adenylate cyclase
FORC8_2514	ENOG4107IX6	phosphate transport regulator
FORC8_2515	ENOG4105CJ3	phosphate transporter
FORC8_2516	ENOG4106MWK	domain protein
FORC8_2519	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FORC8_2520	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FORC8_2521	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC8_2522	ENOG4107ZVW	dihydroneopterin aldolase
FORC8_2523	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FORC8_2524	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
FORC8_2525	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FORC8_2526	ENOG4105VCC	30S ribosomal protein S21
FORC8_2527	ENOG4105KTH	gatB Yqey
FORC8_2528	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FORC8_2529	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FORC8_2530	ENOG4105D01	(LipO)protein
FORC8_2536	ENOG4105CTS	PTS system mannitol-specific
FORC8_2537	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
FORC8_2538	ENOG4105E61	Mannitol repressor protein
FORC8_2539	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
FORC8_2540	ENOG4105GR3	Histidine kinase
FORC8_2543	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FORC8_2544	ENOG410804X	Transcriptional regulator
FORC8_2545	ENOG4105CA9	Pyruvate kinase
FORC8_2547	ENOG4105BZU	Histidine kinase
FORC8_2548	ENOG4108ZP8	Acetolactate synthase small subunit
FORC8_2549	ENOG4105C7K	acetolactate synthase
FORC8_2550	ENOG4108IQE	Amp-dependent synthetase and ligase
FORC8_2551	ENOG41064T2	transcriptional regulator, lysR family
FORC8_2555	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FORC8_2556	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FORC8_2557	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FORC8_2558	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FORC8_2560	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
FORC8_2561	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
FORC8_2562	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FORC8_2563	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FORC8_2564	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FORC8_2565	ENOG4105NWN	ApaG protein
FORC8_2566	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
FORC8_2567	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
FORC8_2569	ENOG4105DWK	Membrane
FORC8_2570	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FORC8_2571	ENOG4105K46	50S ribosomal protein l27
FORC8_2572	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FORC8_2573	ENOG4105EAH	synthase
FORC8_2575	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FORC8_2576	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
FORC8_2580	ENOG4107T0D	ABC, transporter
FORC8_2581	ENOG4106SMU	thiamine transporter membrane protein
FORC8_2582	ENOG4105DP9	ABC transporter
FORC8_2583	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
FORC8_2584	ENOG4105DFU	Cell wall formation (By similarity)
FORC8_2585	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FORC8_2586	ENOG4105F0N	pyrophosphate phospho-hydrolase
FORC8_2588	ENOG41066HZ	AIG2-like family
FORC8_2590	ENOG4105CFU	surface antigen
FORC8_2591	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FORC8_2592	ENOG41061GZ	Protein of unknown function (DUF1107)
FORC8_2593	ENOG4108UUE	Transcriptional regulator
FORC8_2597	ENOG4108I0Y	(ABC) transporter
FORC8_2601	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
FORC8_2603	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
FORC8_2604	ENOG4105C11	sulfate adenylyltransferase), subunit 2
FORC8_2605	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FORC8_2606	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
FORC8_2608	ENOG4105C1J	atp-dependent rna helicase
FORC8_2609	ENOG4107YB6	acetyltransferase, (GNAT) family
FORC8_2611	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FORC8_2613	ENOG4108ZT0	50S ribosomal protein l17
FORC8_2614	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FORC8_2615	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FORC8_2616	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FORC8_2617	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FORC8_2618	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FORC8_2619	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FORC8_2620	ENOG4105VPB	50S ribosomal protein L30
FORC8_2621	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FORC8_2623	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FORC8_2624	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FORC8_2625	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FORC8_2626	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC8_2627	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FORC8_2628	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FORC8_2629	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FORC8_2630	ENOG41083MP	50s ribosomal protein l29
FORC8_2631	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FORC8_2632	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FORC8_2633	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FORC8_2634	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FORC8_2635	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORC8_2636	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FORC8_2637	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FORC8_2638	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FORC8_2639	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FORC8_2640	ENOG4105VFB	Binds the 23S rRNA (By similarity)
FORC8_2641	ENOG4105C25	Primosomal protein n'
FORC8_2642	ENOG4105ETE	Transcriptional regulator (LacI family
FORC8_2644	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
FORC8_2645	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
FORC8_2646	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
FORC8_2647	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
FORC8_2648	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
FORC8_2649	ENOG4105CBT	Fructose-1,6-bisphosphatase
FORC8_2654	ENOG4105CP7	Triose-phosphate isomerase
FORC8_2655	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FORC8_2659	ENOG4105D3Q	Sugar transferase
FORC8_2661	ENOG4108RYC	glycosyltransferase
FORC8_2662	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FORC8_2665	ENOG4105ER6	polysaccharide biosynthesis protein
FORC8_2666	ENOG4107XU6	Glycosyl transferase (Group 1
FORC8_2667	ENOG41066S7	Glycosyltransferase family 52
FORC8_2669	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
FORC8_2671	ENOG4105F0R	Cytidylyltransferase
FORC8_2678	ENOG4105E3R	(LipO)protein
FORC8_2679	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
FORC8_2680	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
FORC8_2681	ENOG4105XA0	heptosyltransferase ii
FORC8_2682	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FORC8_2687	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FORC8_2688	ENOG4105CHR	reductase
FORC8_2690	ENOG4108P1X	synthase
FORC8_2694	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
FORC8_2695	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FORC8_2696	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
FORC8_2697	ENOG41080IJ	Diacylglycerol kinase
FORC8_2698	ENOG4105DKP	glycosyl transferase, family 9
FORC8_2699	ENOG4106WTF	Glycosyl transferase, family 2
FORC8_2701	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
FORC8_2702	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FORC8_2703	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FORC8_2706	ENOG4105KDC	50s ribosomal protein l28
FORC8_2707	ENOG4105W5Q	DNA repair protein (RadC
FORC8_2708	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_2709	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FORC8_2710	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
FORC8_2711	ENOG4105D1S	lipid A biosynthesis
FORC8_2712	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FORC8_2713	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
FORC8_2714	ENOG4105DSJ	YicC domain protein
FORC8_2716	ENOG4108JQ7	(ABC) transporter
FORC8_2718	ENOG4107QRA	Extracellular solute-binding protein, family 5
FORC8_2719	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
FORC8_2720	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
FORC8_2721	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FORC8_2725	ENOG4109015	Biopolymer transport protein exbD tolR
FORC8_2729	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FORC8_2730	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FORC8_2731	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FORC8_2732	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
FORC8_2733	ENOG4105CB5	ATP-dependent DNA helicase recG
FORC8_2735	ENOG4105C2W	permease
FORC8_2736	ENOG4105E0F	Histidine kinase
FORC8_2737	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FORC8_2739	ENOG4108RRZ	Transcription elongation factor GreB
FORC8_2741	ENOG4105BZM	domain protein
FORC8_2743	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
FORC8_2744	ENOG4105MJ2	Competence protein
FORC8_2745	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
FORC8_2746	ENOG4107RK2	ADP-ribose diphosphatase NudE
FORC8_2747	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
FORC8_2748	ENOG4105PIC	general secretion pathway protein N
FORC8_2749	ENOG4105U1E	general secretion pathway protein M
FORC8_2750	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
FORC8_2751	ENOG4108RTD	type II secretion system protein K
FORC8_2752	ENOG4108WWZ	General secretion pathway protein J
FORC8_2753	ENOG4105X5Z	General secretion pathway protein I
FORC8_2754	ENOG4105VWV	general secretion pathway protein h
FORC8_2755	ENOG4108VAU	general secretion pathway protein G
FORC8_2756	ENOG4105D7Q	type ii secretion system
FORC8_2757	ENOG4107QHF	type ii secretion system protein e
FORC8_2759	ENOG4108XKW	General secretion pathway protein C
FORC8_2760	ENOG4105VEJ	Heat shock protein
FORC8_2761	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
FORC8_2762	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
FORC8_2764	ENOG4105SUU	thioesterase domain
FORC8_2765	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FORC8_2766	ENOG4107S2Z	UPF0761 membrane protein
FORC8_2771	ENOG4105C5F	glutamine synthetase
FORC8_2773	ENOG4105CUX	Signal transduction histidine kinase
FORC8_2774	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_2775	ENOG4105BZU	Histidine kinase
FORC8_2776	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FORC8_2777	ENOG4105D4P	Coproporphyrinogen iii oxidase
FORC8_2778	ENOG4105XCT	Protein of unknown function (DUF2489)
FORC8_2779	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
FORC8_2782	ENOG4106RE7	Cytochrome
FORC8_2783	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FORC8_2784	ENOG4105C2M	dna polymerase I
FORC8_2786	ENOG4105D52	delta-aminolevulinic acid dehydratase
FORC8_2787	ENOG4105F8V	Hydrolase, tatD family
FORC8_2788	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FORC8_2789	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
FORC8_2790	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FORC8_2791	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FORC8_2792	ENOG4105JC1	sterol-binding domain protein
FORC8_2793	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FORC8_2794	ENOG4105CGY	Dna recombination protein
FORC8_2796	ENOG4105BZU	Histidine kinase
FORC8_2797	ENOG4105DSF	transport protein
FORC8_2807	ENOG4105K3G	Periplasmic Protein
FORC8_2808	ENOG4108JUA	Transcriptional regulator
FORC8_2809	ENOG4105CBX	hi0933 family
FORC8_2810	ENOG4108V6B	universal stress protein B
FORC8_2811	ENOG41090A1	ferritin
FORC8_2812	ENOG4108M6U	Universal stress protein A
FORC8_2813	ENOG4105EMK	carboxylate amino acid amine transporter
FORC8_2815	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
FORC8_2816	ENOG4105BZU	Histidine kinase
FORC8_2817	ENOG4108VVK	transcriptional Regulator, AsnC
FORC8_2818	ENOG4105DGW	oligopeptidase A
FORC8_2819	ENOG4105D6S	protein involved in catabolism of external DNA
FORC8_2820	ENOG4105DC8	reductase
FORC8_2821	ENOG4107RSM	transcriptional regulator
FORC8_2822	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
FORC8_2823	ENOG4108UHU	Aldolase
FORC8_2824	ENOG4105C6Z	Gluconate
FORC8_2825	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
FORC8_2826	ENOG4105C01	Dihydroxy-acid dehydratase
FORC8_2827	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
FORC8_2828	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
FORC8_2829	ENOG41064T2	transcriptional regulator, lysR family
FORC8_2830	ENOG4105DIQ	Transcriptional regulator
FORC8_2831	ENOG4105D9P	serine threonine protein kinase
FORC8_2837	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FORC8_2838	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FORC8_2839	ENOG4105DEF	Extracellular solute-binding protein, family 5
FORC8_2840	ENOG4108JQ6	ABC transporter
FORC8_2843	ENOG4105MPD	Cytochrome
FORC8_2844	ENOG4105C4R	Atp-dependent dna helicase
FORC8_2845	ENOG41067SE	Tetr family transcriptional regulator
FORC8_2846	ENOG410624X	efflux transporter, rnd family, mfp subunit
FORC8_2847	ENOG4105BZS	acriflavin resistance protein
FORC8_2848	ENOG4105W0Z	cytoplasmic protein
FORC8_2849	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FORC8_2850	ENOG4105EMY	transcriptional regulator
FORC8_2852	ENOG4108Z0R	Transferase
FORC8_2853	ENOG4105SG3	Protein of unknown function (DUF1488)
FORC8_2854	ENOG4105E2X	shikimate dehydrogenase
FORC8_2855	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
FORC8_2856	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FORC8_2857	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FORC8_2858	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FORC8_2859	ENOG4108WI1	Dna topoisomerase
FORC8_2860	ENOG4108RPN	Protein smg homolog
FORC8_2861	ENOG4105C79	DNA protecting protein DprA
FORC8_2863	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FORC8_2864	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FORC8_2865	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FORC8_2866	ENOG4105C1A	potassium transporter peripheral membrane
FORC8_2867	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FORC8_2869	ENOG4108UT2	hemolysin iii
FORC8_2870	ENOG4108N23	SpoOM-related protein
FORC8_2872	ENOG4105PC1	Conserved Protein
FORC8_2874	ENOG4105E27	serine threonine protein kinase
FORC8_2875	ENOG4108Z33	Thiol disulfide Interchange Protein
FORC8_2876	ENOG4106HNH	Acyl-transferase
FORC8_2878	ENOG4105C0P	Mg chelatase subunit ChlI
FORC8_2880	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
FORC8_2881	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FORC8_2882	ENOG4105C01	Dihydroxy-acid dehydratase
FORC8_2883	ENOG4105C7B	Threonine dehydratase
FORC8_2884	ENOG4105F52	Transcriptional regulator
FORC8_2885	ENOG4105CZQ	inner membrane transport protein YdhC
FORC8_2887	ENOG4105EAD	ABC transporter
FORC8_2888	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FORC8_2889	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FORC8_2890	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FORC8_2891	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FORC8_2892	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FORC8_2893	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FORC8_2894	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FORC8_2895	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FORC8_2896	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
FORC8_2897	ENOG410684E	atp synthase
FORC8_2898	ENOG4105FA0	parb-like partition protein
FORC8_2899	ENOG4107QJE	Chromosome Partitioning Protein
FORC8_2900	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FORC8_2901	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FORC8_2903	ENOG4105QTB	Flavodoxin
FORC8_2904	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FORC8_2905	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FORC8_2906	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FORC8_2908	ENOG4105E5Q	amino acid AbC transporter
FORC8_2909	ENOG4105EAB	amino acid AbC transporter
FORC8_2913	ENOG4108JQ7	(ABC) transporter
FORC8_2918	ENOG4105BZU	Histidine kinase
FORC8_2920	ENOG4105CDY	transcriptional regulatory protein
FORC8_2921	ENOG4105CNI	cell division protein FtsW
FORC8_2924	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FORC8_2928	ENOG4108HRK	Histidine kinase
FORC8_2929	ENOG4108VAC	response regulator
FORC8_2931	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FORC8_2932	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_2937	ENOG4105D6U	Sodium Glutamate Symporter
FORC8_2939	ENOG4105DVE	abc transporter atp-binding protein
FORC8_2940	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FORC8_2941	ENOG4105D6U	Sodium Glutamate Symporter
FORC8_2943	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
FORC8_2947	ENOG4105C2I	pirin domain protein
FORC8_2948	ENOG4108VGI	doxx family
FORC8_2950	ENOG4105D03	DNA-3-methyladenine glycosylase II
FORC8_2951	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FORC8_2955	ENOG4105DN9	Na H antiporter
FORC8_2961	ENOG4105NBK	UPF0345 protein
FORC8_2963	ENOG4108K0B	C-di-gmp phosphodiesterase
FORC8_2964	ENOG4105UQX	Mate efflux family protein
FORC8_2965	ENOG4105D3G	Pseudouridine synthase
FORC8_2968	ENOG4105HEI	LysR family (Transcriptional regulator
FORC8_2969	ENOG4108HCJ	Hydrolase
FORC8_2971	ENOG4108KHX	Diguanylate cyclase
FORC8_2973	ENOG4105C4W	S-formylglutathione hydrolase
FORC8_2975	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
FORC8_2976	ENOG4105CC0	LysR family Transcriptional regulator
FORC8_2979	ENOG4105J4Q	Transcriptional regulator
FORC8_2980	ENOG4105CHR	reductase
FORC8_2981	ENOG4105P66	Membrane
FORC8_2982	ENOG4105M5J	Cupin 2, conserved barrel domain protein
FORC8_2985	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
FORC8_2986	ENOG4108UHU	Aldolase
FORC8_2991	ENOG4105CAZ	oligogalacturonide lyase
FORC8_2992	ENOG4105Q26	Siderophore-interacting protein
FORC8_2994	ENOG4105EW9	transcriptional regulator AsnC family
FORC8_2998	ENOG4107W31	Pentapeptide repeat protein
FORC8_2999	ENOG4105EIF	outer membrane protein W
FORC8_3001	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FORC8_3005	ENOG4107WCA	isomerase
FORC8_3006	ENOG4108UVJ	appr-1-p processing domain protein
FORC8_3007	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
FORC8_3013	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
FORC8_3018	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
FORC8_3019	ENOG4105C6Z	Gluconate
FORC8_3020	ENOG4105BZW	Glycerate kinase
FORC8_3021	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FORC8_3028	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FORC8_3030	ENOG4105CUW	cytochrome C-TYPE protein
FORC8_3031	ENOG4107QY8	reductase
FORC8_3033	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FORC8_3034	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
FORC8_3035	ENOG4105ETU	transcriptional activator (TenA
FORC8_3036	ENOG4107Z6I	Thiamine biosynthesis protein
FORC8_3037	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
FORC8_3038	ENOG4108YI8	ABC transporter
FORC8_3039	ENOG4105DWF	phosphomethylpyrimidine kinase
FORC8_3042	ENOG4108TEM	pseudouridine methyltransferase
FORC8_3044	ENOG4108YYI	Protein of unknown function (DUF2810)
FORC8_3045	ENOG4105C5I	Dehydrogenase
FORC8_3047	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
FORC8_3048	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FORC8_3049	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FORC8_3050	ENOG410804D	Sensor Signal Transduction Histidine Kinase
FORC8_3055	ENOG4109015	Biopolymer transport protein exbD tolR
FORC8_3063	ENOG4105DSE	periplasmic solute binding protein
FORC8_3064	ENOG4105DIK	(ABC) transporter
FORC8_3065	ENOG4105CC5	ABC transporter
FORC8_3068	ENOG4105CUG	Oligopeptidase b
FORC8_3069	ENOG4105E5M	Multidrug resistance protein D
FORC8_3070	ENOG4105CYW	agmatinase
FORC8_3071	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
FORC8_3073	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FORC8_3074	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FORC8_3076	ENOG4105DUM	transcriptional regulator, lysR family
FORC8_3083	ENOG4105CQZ	Histidine kinase
FORC8_3084	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_3085	ENOG4105BZU	Histidine kinase
FORC8_3086	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
FORC8_3089	ENOG4105D5U	fad dependent oxidoreductase
FORC8_3091	ENOG4105C0F	tryptophanase EC 4.1.99.1
FORC8_3094	ENOG4105D9N	nucleoside
FORC8_3096	ENOG4105CF1	Alkylated DNA repair protein
FORC8_3097	ENOG4105BZU	Histidine kinase
FORC8_3098	ENOG4108N3W	hemolysin secretion protein
FORC8_3101	ENOG4106TD9	Diguanylate cyclase
FORC8_3102	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FORC8_3103	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
FORC8_3105	ENOG4105E0X	reductase
FORC8_3106	ENOG4108UKZ	OsmC family
FORC8_3107	ENOG4108UW5	maltose o-acetyltransferase
FORC8_3114	ENOG4105JQN	Transcriptional regulator
FORC8_3115	ENOG4105PAD	Hydrolase
FORC8_3118	ENOG4108UUE	Transcriptional regulator
FORC8_3120	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FORC8_3121	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
FORC8_3122	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FORC8_3124	ENOG4105KUU	lipolytic protein G-D-S-L family
FORC8_3125	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
FORC8_3130	ENOG4105ETE	Transcriptional regulator (LacI family
FORC8_3131	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
FORC8_3132	ENOG4108JPW	Aminotransferase
FORC8_3133	ENOG4107STF	Involved in phosphonate degradation (By similarity)
FORC8_3137	ENOG4107RCV	ABC transporter, permease
FORC8_3141	ENOG4108MJ5	VirK protein
FORC8_3142	ENOG4105CJP	fad dependent oxidoreductase
FORC8_3145	ENOG410810E	transcriptional regulator, lysR family
FORC8_3149	ENOG4105DUX	Transporter
FORC8_3150	ENOG4105EJQ	L-serine dehydratase
FORC8_3154	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FORC8_3155	ENOG4105E9H	Lytic Murein transglycosylase
FORC8_3159	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
FORC8_3160	ENOG4108ZC9	flagellar basal-body rod protein flgc
FORC8_3161	ENOG4105W00	Flagellar hook capping protein
FORC8_3162	ENOG4105BZE	flagellar hook protein, FlgE
FORC8_3163	ENOG4108KPB	Flagellar basal-body rod protein FlgF
FORC8_3164	ENOG4105CGA	flagellar basal-body rod protein FlgG
FORC8_3165	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FORC8_3166	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FORC8_3167	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
FORC8_3168	ENOG4105E1Q	flagellar hook-associated protein
FORC8_3169	ENOG4105DTJ	flagellar hook-associated protein
FORC8_3173	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
FORC8_3179	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
FORC8_3180	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FORC8_3181	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FORC8_3183	ENOG4105N14	lysine exporter protein LysE YggA
FORC8_3184	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
FORC8_3187	ENOG4107Z3H	Transcriptional regulator, TetR family
FORC8_3189	ENOG4105CGH	5'-nucleotidase
FORC8_3190	ENOG4105EA8	2-Nitropropane dioxygenase
FORC8_3191	ENOG4105DM4	PTS System
FORC8_3195	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FORC8_3196	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
FORC8_3197	ENOG4105N2W	Transcriptional regulator
FORC8_3199	ENOG4105CH6	catalase
FORC8_3201	ENOG4108RWI	nicotinamidase
FORC8_3203	ENOG4107RH7	Nicotinate phosphoribosyltransferase
FORC8_3209	ENOG4105ETT	transcriptional Regulator, LysR family
FORC8_3212	ENOG4105RW8	MltA-interacting MipA family protein
FORC8_3213	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
FORC8_3214	ENOG4105VYW	UPF0251 protein
FORC8_3219	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FORC8_3220	ENOG4107S8C	mandelate racemase muconate lactonizing
FORC8_3225	ENOG4108Z4X	TRANSCRIPTIONal
FORC8_3230	ENOG4107RZC	phospholipase d
FORC8_3238	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FORC8_3246	ENOG41086KC	Transcriptional regulator
FORC8_3248	ENOG4105BZU	Histidine kinase
FORC8_3252	ENOG4107KET	secretion protein, HlyD family
FORC8_3255	ENOG4107RUE	extracellular solute-binding protein family 1
FORC8_3256	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FORC8_3259	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
FORC8_3260	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
FORC8_3261	ENOG4105HDK	L-asparaginase
FORC8_3262	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FORC8_3266	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
FORC8_3267	ENOG4108ZX5	transcriptional regulator
FORC8_3268	ENOG4105CHR	reductase
FORC8_3270	ENOG4105CPQ	Dehydrogenase
FORC8_3271	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FORC8_3274	ENOG4107RSM	transcriptional regulator
FORC8_3276	ENOG4105C1J	atp-dependent rna helicase
FORC8_3284	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FORC8_3285	ENOG410874W	AraC family transcriptional regulator
FORC8_3291	ENOG4105CKW	Inner membrane protein yedI
FORC8_3292	ENOG4105EKE	dihydroorotase
FORC8_3294	ENOG4105QVC	MOSC domain-containing protein
FORC8_3294	ENOG4105QVC	MOSC domain-containing protein
FORC8_3295	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
FORC8_3296	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FORC8_3305	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
FORC8_3306	ENOG4105EHG	Permease protein
FORC8_3308	ENOG4106GFD	transport protein
FORC8_3309	ENOG41090AP	transport protein
FORC8_3310	ENOG4105WQ5	TonB family
FORC8_3311	ENOG4105D4P	Coproporphyrinogen iii oxidase
FORC8_3312	ENOG41090JE	Utilization Protein
FORC8_3313	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
FORC8_3315	ENOG4107R88	Chemotaxis protein (CheV)
FORC8_3316	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
FORC8_3319	ENOG4105CT4	transporter
FORC8_3320	ENOG4105EF1	ribulokinase
FORC8_3322	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
FORC8_3323	ENOG4108K4B	hydrolase
FORC8_3325	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FORC8_3326	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
FORC8_3327	ENOG4105CT4	transporter
FORC8_3333	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
FORC8_3335	ENOG4105C5Q	Transcriptional regulator
FORC8_3338	ENOG4105KXC	Collagenase
FORC8_3343	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FORC8_3344	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
FORC8_3345	ENOG4108M6U	Universal stress protein A
FORC8_3346	ENOG4105C5H	ABC transporter
FORC8_3349	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FORC8_3351	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FORC8_3353	ENOG4108HK0	-acetyltransferase
FORC8_3355	ENOG410620I	Diguanylate cyclase
FORC8_3359	ENOG4108IJF	Heavy metal efflux pump, CzcA
FORC8_3363	ENOG4108IEG	Formate dehydrogenase Alpha subunit
FORC8_3366	ENOG4107QWP	ABC-2 type transporter
FORC8_3367	ENOG4105CJ1	ABC, transporter
FORC8_3369	ENOG4108NVR	Methyl-accepting chemotaxis
FORC8_3372	ENOG4105JAB	phenazine biosynthesis protein, phzf family
FORC8_3373	ENOG4108V1U	phospholipid-binding protein
FORC8_3375	ENOG4105D6J	arsenicaL-resistance protein
FORC8_3378	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
FORC8_3379	ENOG4105CTS	PTS system mannitol-specific
FORC8_3380	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
FORC8_3382	ENOG4107Z1W	Fructose transport system kinase
FORC8_3387	ENOG4105E0U	tyrosine-specific transport protein
FORC8_3389	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_3390	ENOG4105DWD	nucleoside recognition domain protein
FORC8_3394	ENOG4105DR5	peptidase
FORC8_3396	ENOG4105CR8	Transcriptional regulator
FORC8_3397	ENOG4105E5M	Multidrug resistance protein D
FORC8_3399	ENOG4105VW4	glutaredoxin 3
FORC8_3400	ENOG4108SXK	Transporter Drug Metabolite Exporter family
FORC8_3406	ENOG4105SUT	Transcriptional Regulator AraC Family
FORC8_3412	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
FORC8_3413	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
FORC8_3417	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
FORC8_3418	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FORC8_3419	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FORC8_3425	ENOG4105VEQ	Cold shock protein
FORC8_3427	ENOG4107SDU	Methyl-accepting chemotaxis
FORC8_3428	ENOG4105BZU	Histidine kinase
FORC8_3432	ENOG4107R39	(ABC) transporter
FORC8_3434	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_3435	ENOG4108RMU	ferritin dps family protein
FORC8_3438	ENOG4105C0A	alcohol dehydrogenase
FORC8_3439	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
FORC8_3447	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FORC8_3448	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FORC8_3449	ENOG4105MIR	Phenylalanine 4-monooxygenase
FORC8_3450	ENOG41090A4	Pterin carbinolamine dehydratase
FORC8_3454	ENOG4105VRT	cytoplasmic protein
FORC8_3455	ENOG4105C1J	atp-dependent rna helicase
FORC8_3456	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
FORC8_3457	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FORC8_3459	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
FORC8_3461	ENOG4105CKI	cobalamin synthesis protein
FORC8_3462	ENOG4105C1J	atp-dependent rna helicase
FORC8_3466	ENOG4105CXC	rtn protein
FORC8_3467	ENOG4105DKW	ABC transporter
FORC8_3468	ENOG4108N3W	hemolysin secretion protein
FORC8_3470	ENOG4105DUM	transcriptional regulator, lysR family
FORC8_3471	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
FORC8_3472	ENOG4105C4X	radical SAM domain protein
FORC8_3482	ENOG4107S17	Phosphate-binding protein
FORC8_3485	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
FORC8_3486	ENOG4105C1J	atp-dependent rna helicase
FORC8_3487	ENOG4105BZU	Histidine kinase
FORC8_3489	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FORC8_3490	ENOG4107SDU	Methyl-accepting chemotaxis
FORC8_3493	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
FORC8_3494	ENOG4105CGU	Enoyl-CoA hydratase
FORC8_3495	ENOG4107QX3	carboxylase
FORC8_3496	ENOG4105C1G	acyl-Coa dehydrogenase
FORC8_3498	ENOG4105CHU	acetyl-coa acetyltransferase
FORC8_3499	ENOG4105C26	Dehydrogenase
FORC8_3501	ENOG4105E39	Enoyl-CoA hydratase
FORC8_3502	ENOG4105E39	Enoyl-CoA hydratase
FORC8_3503	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FORC8_3504	ENOG4105CHR	reductase
FORC8_3505	ENOG4105E2S	oxidase) subunit II
FORC8_3506	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FORC8_3507	ENOG4105CCU	oxidase (Subunit III)
FORC8_3509	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FORC8_3512	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FORC8_3514	ENOG4105E5Z	arginine transporter ATP-binding subunit
FORC8_3515	ENOG4106PMH	Extracellular solute-binding protein family 3
FORC8_3516	ENOG4105GBT	ABC transporter
FORC8_3517	ENOG4105DMR	ABC, transporter
FORC8_3519	ENOG4105DUM	transcriptional regulator, lysR family
FORC8_3520	ENOG4107MKT	Stringent starvation protein a
FORC8_3521	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
FORC8_3522	ENOG4107QSN	dihydrolipoamide acetyltransferase
FORC8_3523	ENOG4105CPP	Dehydrogenase, E1 component
FORC8_3524	ENOG4107RUY	(E1 component), alpha subunit
FORC8_3527	ENOG4105R8A	Heat shock protein
FORC8_3528	ENOG4106E5D	Protein of unknown function (DUF461)
FORC8_3534	ENOG4105DHS	permease protein
FORC8_3535	ENOG4105CM4	permease protein
FORC8_3536	ENOG4108IPW	abc transporter atp-binding protein
FORC8_3537	ENOG4108Z6Z	Transcriptional regulator
FORC8_3546	ENOG4105EM2	membrane
FORC8_3547	ENOG41088T4	Helicase IV
FORC8_3548	ENOG4108Z5K	methylglyoxal synthase
FORC8_3549	ENOG4108SV3	Tmao reductase system periplasmic protein tort
FORC8_3550	ENOG4105BZU	Histidine kinase
FORC8_3553	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FORC8_3554	ENOG4105ENH	Sulfatase
FORC8_3555	ENOG4105ENH	Sulfatase
FORC8_3558	ENOG4105ENH	Sulfatase
FORC8_3559	ENOG4105C4X	radical SAM domain protein
FORC8_3560	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FORC8_3566	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FORC8_3567	ENOG41064T2	transcriptional regulator, lysR family
FORC8_3568	ENOG4107TE5	Lipid kinase
FORC8_3569	ENOG4108YDI	single-species biofilm formation on inanimate substrate
FORC8_3572	ENOG4105C4X	radical SAM domain protein
FORC8_3574	ENOG4105F2V	VRR-NUC domain-containing protein
FORC8_3577	ENOG4105D0M	Protease HtpX homolog
FORC8_3578	ENOG4108V0P	LemA family
FORC8_3579	ENOG4105CEE	C4-dicarboxylate transporter
FORC8_3583	ENOG4108MGY	Histidine kinase
FORC8_3584	ENOG4107KBT	8-Amino-7-oxononanoate synthase
FORC8_3585	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
FORC8_3587	ENOG4105KXC	Collagenase
FORC8_3589	ENOG4106R3P	AraC family transcriptional regulator
FORC8_3604	ENOG4105CDV	Ompa motb domain protein
FORC8_3606	ENOG4108WAV	Transcriptional regulator
FORC8_3607	ENOG41064T2	transcriptional regulator, lysR family
FORC8_3609	ENOG4105BZU	Histidine kinase
FORC8_3610	ENOG4105BZU	Histidine kinase
FORC8_3611	ENOG4108WQH	regulatoR
FORC8_3612	ENOG4105BZU	Histidine kinase
FORC8_3614	ENOG4108WQH	regulatoR
FORC8_3618	ENOG4107R88	Chemotaxis protein (CheV)
FORC8_3621	ENOG4105FR1	rard protein
FORC8_3623	ENOG4106CKV	Pap2 superfamily protein
FORC8_3627	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
FORC8_3631	ENOG4107RGH	Aldehyde dehydrogenase
FORC8_3632	ENOG4107QPK	)-transporter
FORC8_3634	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
FORC8_3635	ENOG4106YYS	transcriptional regulatory protein
FORC8_3637	ENOG4105CBC	glutamate synthase
FORC8_3638	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
FORC8_3643	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FORC8_3644	ENOG4108UYE	Lactoylglutathione lyase
FORC8_3648	ENOG4105CJW	magnesium transporter
FORC8_3654	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FORC8_3657	ENOG4105HDD	phospholipase
FORC8_3662	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FORC8_3663	ENOG4105CR8	Transcriptional regulator
FORC8_3671	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC8_3672	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FORC8_3673	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FORC8_3681	ENOG4105DM4	PTS System
FORC8_3682	ENOG4105DE4	1-phosphofructokinase
FORC8_3683	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
FORC8_3684	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
FORC8_3687	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
FORC8_3688	ENOG4105DRP	amino acid AbC transporter
FORC8_3689	ENOG4106TNF	Periplasmic binding protein
FORC8_3690	ENOG4105E5Q	amino acid AbC transporter
FORC8_3691	ENOG4105CDA	abc transporter atp-binding protein
FORC8_3692	ENOG4105CA9	Pyruvate kinase
FORC8_3693	ENOG4105CXY	transporter
FORC8_3694	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
FORC8_3696	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
FORC8_3698	ENOG4108I6A	alcohol dehydrogenase
FORC8_3699	ENOG4105CF7	AraC family transcriptional regulator
FORC8_3701	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FORC8_3702	ENOG4105CKU	formyltetrahydrofolate synthetase
FORC8_3703	ENOG4107RE1	Inosine-guanosine kinase
FORC8_3706	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FORC8_3707	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FORC8_3709	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
FORC8_3710	ENOG4105C1J	atp-dependent rna helicase
FORC8_3711	ENOG4108M8H	domain protein
FORC8_3714	ENOG4105DS1	cytochrome b561
FORC8_3715	ENOG4108YYC	ycei family
FORC8_3716	ENOG4105TMB	Formate nitrite transporter
FORC8_3717	ENOG4105DUM	transcriptional regulator, lysR family
FORC8_3718	ENOG4108UQ5	membrane protein YcdZ
FORC8_3719	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
FORC8_3720	ENOG4105CGH	5'-nucleotidase
FORC8_3721	ENOG4105DU1	integral membrane protein, terc
FORC8_3724	ENOG4108M0H	Extracellular lipase
FORC8_3725	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FORC8_3728	ENOG4105KA0	thioesterase Superfamily protein
FORC8_3730	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
FORC8_3734	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FORC8_3736	ENOG4105BZU	Histidine kinase
FORC8_3737	ENOG4105RKW	reductase (By
FORC8_3739	ENOG4108I0Y	(ABC) transporter
FORC8_3740	ENOG4105CV6	ABC transporter, permease
FORC8_3742	ENOG4107R7A	Allophanate hydrolase subunit 2
FORC8_3743	ENOG4105P4J	Allophanate hydrolase, subunit 1
FORC8_3744	ENOG4105E7W	lamb ycsf family protein
FORC8_3745	ENOG4105BZU	Histidine kinase
FORC8_3746	ENOG4105CMR	udp-glucose 4-epimerase
FORC8_3748	ENOG4105CWB	LysR family transcriptional Regulator
FORC8_3749	ENOG4105CD5	CoA-binding domain protein
FORC8_3751	ENOG4105CPF	Cell wall formation (By similarity)
FORC8_3753	ENOG4108ZJT	translation initiation factor, Sui1
FORC8_3762	ENOG4105MQ5	zona occludens toxin
FORC8_3767	ENOG4105EJC	lysr family transcriptional regulator
FORC8_3769	ENOG4108M6U	Universal stress protein A
FORC8_3775	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FORC8_3776	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FORC8_3779	ENOG4105BZU	Histidine kinase
FORC8_3783	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
FORC8_3784	ENOG4105E0C	molybdate abc transporter
FORC8_3785	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FORC8_3786	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FORC8_3787	ENOG4105WXI	Bacterial OB fold (BOF) protein
FORC8_3789	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FORC8_3790	ENOG4105CGF	Aromatic amino acid aminotransferase
FORC8_3791	ENOG4105ECQ	AraC Family Transcriptional Regulator
FORC8_3792	ENOG4107QI1	Mate efflux family protein
FORC8_3793	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
FORC8_3794	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
FORC8_3797	ENOG4105BZS	acriflavin resistance protein
FORC8_3803	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
FORC8_3804	ENOG4105C5Q	Transcriptional regulator
FORC8_3805	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
FORC8_3806	ENOG4105CXY	transporter
FORC8_3807	ENOG4108KX4	response regulator
FORC8_3808	ENOG4105BZU	Histidine kinase
FORC8_3809	ENOG4105CXY	transporter
FORC8_3810	ENOG4105EIP	mannose-6-phosphate isomerase
FORC8_3814	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FORC8_3815	ENOG4105K63	Thioredoxin
FORC8_3816	ENOG4108ISG	Major Facilitator
FORC8_3818	ENOG4107QI1	Mate efflux family protein
FORC8_3819	ENOG4105VXR	cytoplasmic protein
FORC8_3824	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
FORC8_3827	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FORC8_3828	ENOG4105TMB	Formate nitrite transporter
FORC8_3829	ENOG4105WZK	nitrite reductase NADPH small subunit
FORC8_3830	ENOG4107QZF	nitrite reductase NADPH large subunit
FORC8_3831	ENOG4105NXH	GreA GreB family elongation factor
FORC8_3837	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FORC8_3842	ENOG4108NVR	Methyl-accepting chemotaxis
FORC8_3843	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FORC8_3846	ENOG4105CXG	d-lactate dehydrogenase
FORC8_3847	ENOG4105CC0	LysR family Transcriptional regulator
FORC8_3848	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
FORC8_3849	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
FORC8_3851	ENOG4105C5W	Aldolase
FORC8_3852	ENOG4106RE7	Cytochrome
FORC8_3853	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
FORC8_3855	ENOG4105C2C	drug resistance transporter, Bcr CflA
FORC8_3857	ENOG4105QNF	Outer membrane lipoprotein
FORC8_3861	ENOG4105EYH	Exonuclease
FORC8_3867	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FORC8_3876	ENOG4108ZF3	Phosphatase
FORC8_3879	ENOG4106VK6	Flagellar motor protein
FORC8_3884	ENOG4105D9P	serine threonine protein kinase
FORC8_3889	ENOG4105F8J	Adenylate Guanylate cyclase
FORC8_3892	ENOG4108IG5	Transcriptional regulator
FORC8_3895	ENOG4107QZF	nitrite reductase NADPH large subunit
FORC8_3896	ENOG4105D7T	ABC transporter
FORC8_3897	ENOG4105DG7	nitrate ABC transporter
FORC8_3902	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FORC8_3904	ENOG4108R6G	acetyltransferase
FORC8_3905	ENOG4105C44	Serine transporter
FORC8_3906	ENOG4105BZU	Histidine kinase
FORC8_3910	ENOG4105G6Z	alkaline phosphatase
FORC8_3913	ENOG4105ETX	regulatoR
FORC8_3917	ENOG4108I5U	Uridine phosphorylase
FORC8_3918	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
FORC8_3920	ENOG4105ETE	Transcriptional regulator (LacI family
FORC8_3921	ENOG4108RVA	ribokinase
FORC8_3922	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
FORC8_3923	ENOG4105CNN	ABC, transporter
FORC8_3924	ENOG4105C2J	ABC transporter
FORC8_3925	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
FORC8_3926	ENOG4108K0B	C-di-gmp phosphodiesterase
FORC8_3927	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
FORC8_3937	ENOG4105BZU	Histidine kinase
FORC8_3938	ENOG4105CA0	peroxidase
FORC8_3939	ENOG4105BZU	Histidine kinase
FORC8_3941	ENOG4107QX8	SPFH domain, Band 7 family protein
FORC8_3943	ENOG4108RCM	Nitroreductase
FORC8_3944	ENOG4108IJ7	Glycine betaine
FORC8_3945	ENOG4108HQS	Glycine betaine
FORC8_3947	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
FORC8_3948	ENOG4105C26	Dehydrogenase
FORC8_3949	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
FORC8_3950	ENOG4105BZU	Histidine kinase
FORC8_3951	ENOG4105CHR	reductase
FORC8_3952	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FORC8_3954	ENOG4105E39	Enoyl-CoA hydratase
FORC8_3955	ENOG4105C1G	acyl-Coa dehydrogenase
FORC8_3956	ENOG4105C26	Dehydrogenase
FORC8_3957	ENOG4105CHU	acetyl-coa acetyltransferase
FORC8_3959	ENOG4105C1G	acyl-Coa dehydrogenase
FORC8_3960	ENOG4107QX3	carboxylase
FORC8_3961	ENOG4108IPT	Naphthoate synthase
FORC8_3962	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FORC8_3963	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
FORC8_3964	ENOG4105BZU	Histidine kinase
FORC8_3967	ENOG4105EGS	Mechanosensitive ion channel
FORC8_3968	ENOG4108UW5	maltose o-acetyltransferase
FORC8_3969	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
FORC8_3970	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FORC8_3971	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FORC8_3972	ENOG4108S58	Phenazine biosynthesis protein PhzF
FORC8_3973	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
FORC8_3976	ENOG4105G9V	cytochrome C
FORC8_3979	ENOG4105DZS	Phenylacetate-CoA ligase
FORC8_3980	ENOG4108IV0	ABC, transporter
FORC8_3985	ENOG4105C0Z	ABC transporter
FORC8_3986	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
FORC8_3987	ENOG4105BZJ	Electron transfer flavoprotein
FORC8_3988	ENOG4105C10	Electron transfer flavoprotein
FORC8_3989	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FORC8_3990	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FORC8_3992	ENOG4106050	phage regulatory protein, rha family
FORC8_4010	ENOG4105KSC	Transcriptional regulator, TraR DksA family
FORC8_4023	ENOG4105ED4	portal protein
FORC8_4037	ENOG4105BZU	Histidine kinase
FORC8_4040	ENOG4108KU3	Integrase
FORC8_4041	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FORC8_4042	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FORC8_4044	ENOG4108UNF	response regulator
FORC8_4045	ENOG4107RGM	aldo keto reductase
FORC8_4048	ENOG4105CMQ	Chloride channel
FORC8_4050	ENOG4105C5A	transporter
FORC8_4052	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FORC8_4053	ENOG4105D06	uba thif-type nad fad binding protein
FORC8_4057	ENOG4105KHC	sulfurtransferase
FORC8_4058	ENOG4105BZU	Histidine kinase
FORC8_4062	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FORC8_4063	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FORC8_4064	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_4065	ENOG4105DXI	Major Facilitator superfamily
FORC8_4066	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FORC8_4067	ENOG4105UYK	outer membrane protein a
FORC8_4068	ENOG4107VXZ	Hydrolase
FORC8_4069	ENOG4108YZN	class I peptide chain release factor
FORC8_4070	ENOG4108N3W	hemolysin secretion protein
FORC8_4073	ENOG4107YWA	deoxycytidylate deaminase
FORC8_4074	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FORC8_4077	ENOG4105WH1	Two component transcriptional regulator luxr family
FORC8_4078	ENOG4105BZU	Histidine kinase
FORC8_4081	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
FORC8_4083	ENOG4105CUW	cytochrome C-TYPE protein
FORC8_4084	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
FORC8_4086	ENOG4105CHU	acetyl-coa acetyltransferase
FORC8_4090	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FORC8_4091	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FORC8_4096	ENOG4105EW9	transcriptional regulator AsnC family
FORC8_4100	ENOG4105EFX	secretion protein, HlyD family
FORC8_4102	ENOG4105BZU	Histidine kinase
FORC8_4103	ENOG4108QGH	periplasmic
FORC8_4104	ENOG41082IR	Excinuclease ABC C subunit domain protein
FORC8_4105	ENOG4108YXG	UPF0502 protein
FORC8_4108	ENOG41090HJ	UPF0265 protein
FORC8_4110	ENOG4105EE0	oxidoreductase
FORC8_4111	ENOG4105BZU	Histidine kinase
FORC8_4115	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
FORC8_4116	ENOG4108XM1	transcriptional regulator AsnC family
FORC8_4117	ENOG4105DVH	amino acid
FORC8_4120	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FORC8_4121	ENOG4105CJW	magnesium transporter
FORC8_4122	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
FORC8_4123	ENOG4105DZC	cytosine deaminase
FORC8_4125	ENOG4105EST	Metal Dependent Phosphohydrolase
FORC8_4127	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
FORC8_4129	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FORC8_4133	ENOG4108Z33	Thiol disulfide Interchange Protein
FORC8_4136	ENOG4105EMU	Dehydrogenase
FORC8_4137	ENOG4107EXC	regulatoR
FORC8_4138	ENOG4105JJR	Histidine kinase
FORC8_4140	ENOG41080IJ	Diacylglycerol kinase
FORC8_4141	ENOG4105DIJ	Phosphoethanolamine transferase
FORC8_4142	ENOG4105EP9	oxidoreductase
FORC8_4147	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
FORC8_4149	ENOG4108NRW	Phospholipase, patatin family
FORC8_4150	ENOG4105EUB	pirin domain protein
FORC8_4151	ENOG4105VEQ	Cold shock protein
FORC8_4153	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
FORC8_4156	ENOG4105DZ1	carboxypeptidase
FORC8_4157	ENOG4105CYM	Glutathione S-transferase
FORC8_4159	ENOG4105NAE	bifunctional deaminase-reductase domain protein
FORC8_4163	ENOG4105CHR	reductase
FORC8_4166	ENOG4108P3C	
FORC8_4170	ENOG4105EG2	ABC transporter, permease
FORC8_4171	ENOG4105D56	permease protein
FORC8_4172	ENOG4107FKK	extracellular solute-binding protein family 1
FORC8_4173	ENOG4108IJ9	(ABC) transporter
FORC8_4177	ENOG4105D75	Capsular exopolysaccharide family
FORC8_4179	ENOG4105CPK	Glycosyl transferase (Group 1
FORC8_4185	ENOG4105V0I	UPF0267 protein
FORC8_4186	ENOG4108WUH	Transcriptional regulator, TetR family
FORC8_4187	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
FORC8_4188	ENOG4108RXX	maleylacetoacetate isomerase
FORC8_4189	ENOG4105CH6	catalase
FORC8_4190	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FORC8_4191	ENOG4105DM4	PTS System
FORC8_4192	ENOG4108YRF	PTS System
FORC8_4194	ENOG4106R3P	AraC family transcriptional regulator
FORC8_4195	ENOG4105DM4	PTS System
FORC8_4196	ENOG4105EIP	mannose-6-phosphate isomerase
FORC8_4198	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
FORC8_4200	ENOG4105BZU	Histidine kinase
FORC8_4201	ENOG4105CZN	Potassium uptake protein
FORC8_4204	ENOG4105BZU	Histidine kinase
FORC8_4205	ENOG4105BZ1	(ABC) transporter
FORC8_4206	ENOG4105E0K	tonB-dependent siderophore receptor
FORC8_4207	ENOG4105E0A	ABC, transporter
FORC8_4208	ENOG4108HUF	Transporter
FORC8_4209	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
FORC8_4211	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FORC8_4215	ENOG4108JJ6	Type I secretion system ATPase
FORC8_4217	ENOG41086KC	Transcriptional regulator
FORC8_4218	ENOG41086KC	Transcriptional regulator
FORC8_4220	ENOG41069D7	Methyl-accepting chemotaxis
FORC8_4221	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FORC8_4225	ENOG4107QVM	von Willebrand factor, type A
FORC8_4229	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FORC8_4230	ENOG4105E2Z	phosphate ABC transporter (Permease
FORC8_4231	ENOG4105C8U	phosphate abc transporter
FORC8_4232	ENOG4107S17	Phosphate-binding protein
FORC8_4233	ENOG4108NVR	Methyl-accepting chemotaxis
FORC8_4237	ENOG4105D05	Receptor
FORC8_4238	ENOG4105CUG	Oligopeptidase b
FORC8_4239	ENOG4105C1J	atp-dependent rna helicase
FORC8_4241	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
FORC8_4242	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FORC8_4243	ENOG4108XDN	Transcriptional regulator
FORC8_4244	ENOG4107SEY	Conserved Protein
FORC8_4245	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FORC8_4248	ENOG4106TD9	Diguanylate cyclase
FORC8_4249	ENOG4105KK7	inner membrane protein YiaW
FORC8_4250	ENOG4105EFX	secretion protein, HlyD family
FORC8_4251	ENOG4108V7D	UPF0397 protein
FORC8_4252	ENOG4108JJB	ABC transporter
FORC8_4255	ENOG4105GXZ	Ferredoxin-type protein NapH
FORC8_4256	ENOG4108BGM	Quinol dehydrogenase periplasmic component
FORC8_4257	ENOG4105WCN	acetyltransferase
FORC8_4260	ENOG4105YE1	PilZ domain
FORC8_4261	ENOG4108NVR	Methyl-accepting chemotaxis
FORC8_4262	ENOG4105DAN	ATP-dependent protease
FORC8_4264	ENOG4108JQ5	ABC transporter
FORC8_4266	ENOG4105CC0	LysR family Transcriptional regulator
FORC8_4267	ENOG4105DAA	L-lactate
FORC8_4268	ENOG4105DMF	Dehydrogenase
FORC8_4270	ENOG4105D64	Mechanosensitive ion channel
FORC8_4277	ENOG4105CPQ	Dehydrogenase
FORC8_4278	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FORC8_4279	ENOG4105BZU	Histidine kinase
FORC8_4280	ENOG4107R0W	ABC transporter
FORC8_4282	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FORC8_4284	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FORC8_4288	ENOG4105EXG	Transcriptional regulator
FORC8_4289	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
FORC8_4293	ENOG4107SSZ	Phosphatase
FORC8_4299	ENOG4108JIR	Flagellum-specific ATP synthase
FORC8_4301	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FORC8_4302	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
FORC8_4304	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_4307	ENOG4105DD5	Flagellar motor switch protein
FORC8_4308	ENOG4105CN7	Flagellar biosynthetic protein FliP
FORC8_4309	ENOG4105VS8	Flagellar biosynthetic protein fliq
FORC8_4310	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
FORC8_4311	ENOG4105D00	flagellar biosynthetic protein flhB
FORC8_4314	ENOG4105I03	Flagellin
FORC8_4316	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
FORC8_4317	ENOG4105MQ3	flagellar protein FliS
FORC8_4322	ENOG4107RD7	Flagellar Motor Protein, MotA
FORC8_4323	ENOG4105ER2	Ompa motb domain protein
FORC8_4325	ENOG4105KWG	Pfam:DUF1696
FORC8_4329	ENOG4105C6N	Formate acetyltransferase
FORC8_4330	ENOG4105F1A	Pyruvate formate-lyase
FORC8_4331	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FORC8_4333	ENOG4105I4A	GCN5-related N-acetyltransferase
FORC8_4336	ENOG4105CNH	Multidrug resistance protein MdtL
FORC8_4337	ENOG4105G2Y	Transcriptional regulator
FORC8_4344	ENOG4105IPI	Membrane
FORC8_4345	ENOG41068P6	UPF0319 protein
FORC8_4347	ENOG4105DP0	ferredoxin-NADP reductase
FORC8_4349	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
FORC8_4350	ENOG4105ETT	transcriptional Regulator, LysR family
FORC8_4352	ENOG4108RCM	Nitroreductase
FORC8_4353	ENOG4108ZX5	transcriptional regulator
FORC8_4355	ENOG4105DZ1	carboxypeptidase
FORC8_4358	ENOG4105C72	UPF0176 protein
FORC8_4359	ENOG4108M1A	Chitin-binding protein
FORC8_4360	ENOG4108NRW	Phospholipase, patatin family
FORC8_4361	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
FORC8_4363	ENOG4105DAY	polysaccharide export protein
FORC8_4365	ENOG4105D75	Capsular exopolysaccharide family
FORC8_4367	ENOG4105N0V	mono-oxygenase ydhR
FORC8_4370	ENOG4105CK2	sodium dicarboxylate symporter
FORC8_4372	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FORC8_4373	ENOG4108P2H	Inner membrane protein YjiG
FORC8_4374	ENOG41074DU	domain protein
FORC8_4377	ENOG4107T9C	Alpha amylase catalytic region
FORC8_4378	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
FORC8_4379	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FORC8_4380	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
FORC8_4381	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
FORC8_4383	ENOG41061ZR	Transcriptional regulator
FORC8_4389	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FORC8_4390	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
FORC8_4392	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
FORC8_4394	ENOG4105D5Q	Arginine ornithine antiporter
FORC8_4395	ENOG4105CXN	decarboxylase
FORC8_4399	ENOG4108K8S	endonuclease I
FORC8_4403	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
FORC8_4408	ENOG4105DR5	peptidase
FORC8_4410	ENOG4107RAN	Peptidase, M16
FORC8_4411	ENOG4105C8Q	Methyl-accepting chemotaxis
FORC8_4412	ENOG4105E0A	ABC, transporter
FORC8_4413	ENOG4108U1V	ABC transporter, permease
FORC8_4414	ENOG4105DQ5	transport system permease protein
FORC8_4415	ENOG4108HUF	Transporter
FORC8_4416	ENOG4105GAV	receptor
FORC8_4417	ENOG4105E0K	tonB-dependent siderophore receptor
FORC8_4419	ENOG4105DUU	IucA IucC family protein
FORC8_4421	ENOG4105DBM	Siderophore biosynthesis protein
FORC8_4422	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FORC8_4423	ENOG4108JP0	extracellular solute-binding protein family 1
FORC8_4424	ENOG4105DHQ	Histidine kinase
FORC8_4425	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FORC8_4426	ENOG4105CI1	PTS System
FORC8_4432	ENOG4105CKK	Glycosyl transferase, family 2
FORC8_4436	ENOG4108ZHJ	Organic hydroperoxide resistance protein
FORC8_4437	ENOG4105K56	Transcriptional regulator
FORC8_4438	ENOG4105D3R	alkyl hydroperoxide reductase
FORC8_4439	ENOG4108JU3	Alkyl hydroperoxide reductase
FORC8_4443	ENOG4105EXG	Transcriptional regulator
FORC8_4444	ENOG4105ECQ	AraC Family Transcriptional Regulator
FORC8_4445	ENOG4105DU6	RNA polymerase
FORC8_4447	ENOG4108N3W	hemolysin secretion protein
FORC8_4448	ENOG4105W8I	Transcriptional regulator
FORC8_4449	ENOG4105F8D	glycoside hydrolase family 4
FORC8_4453	ENOG4108RPX	mosc domain containing protein
FORC8_4454	ENOG4105C1J	atp-dependent rna helicase
FORC8_4457	ENOG4105CF7	AraC family transcriptional regulator
FORC8_4459	ENOG4105BZ1	(ABC) transporter
FORC8_4461	ENOG4105EW9	transcriptional regulator AsnC family
FORC8_4468	ENOG4105CK7	Sodium proline symporter
FORC8_4470	ENOG4105C26	Dehydrogenase
FORC8_4473	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
FORC8_4474	ENOG4105CQZ	Histidine kinase
FORC8_4475	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FORC8_4476	ENOG4107QZV	Type I secretion membrane fusion protein
FORC8_4479	ENOG4108JJA	ABC, transporter
FORC8_4482	ENOG4108J59	Extracellular solute-binding protein, family 5
FORC8_4484	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
FORC8_4485	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC8_4486	ENOG4105C5Y	PTS System
FORC8_4487	ENOG4105FCK	Membrane
FORC8_4488	ENOG4105EC3	peptidase S51, dipeptidase E
FORC8_4492	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
FORC8_4493	ENOG4106RMF	ParB family