locus-tag	class	description
FORC23_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FORC23_0004	COG1126	abc transporter atp-binding protein
FORC23_0005	COG0594	ribonuclease P activity
FORC23_0006	COG0706	membrane insertase activity
FORC23_0007	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FORC23_0008	COG4974	Belongs to the 'phage' integrase family
FORC23_0014	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FORC23_0015	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FORC23_0016	COG0732	type I restriction modification DNA specificity domain
FORC23_0027	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC23_0028	COG0445	tRNA wobble uridine modification
FORC23_0029	COG0357	Ribosomal RNA small subunit methyltransferase G
FORC23_0030	COG1192	Involved in chromosome partitioning
FORC23_0031	COG1475	DNA binding
FORC23_0032	COG3312	ion transport
FORC23_0033	COG0356	it plays a direct role in the translocation of protons across the membrane
FORC23_0036	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FORC23_0037	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FORC23_0038	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FORC23_0039	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FORC23_0040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FORC23_0041	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FORC23_0042	COG0765	amino acid transport
FORC23_0043	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC23_0044	COG2814	Major facilitator Superfamily
FORC23_0045	COG0583	DNA-binding transcription factor activity
FORC23_0047	COG0129	dihydroxy-acid dehydratase activity
FORC23_0048	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FORC23_0049	COG3978	acetolactate synthase activity
FORC23_0051	COG0606	chelatase, subunit chli
FORC23_0053	COG0204	Acyl-transferase
FORC23_0054	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC23_0055	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FORC23_0057	COG3084	Protein conserved in bacteria
FORC23_0058	COG4326	sporulation control protein
FORC23_0059	COG1272	protein, Hemolysin III
FORC23_0061	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC23_0062	COG0569	domain protein
FORC23_0063	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC23_0063	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC23_0064	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FORC23_0065	COG0242	peptide deformylase activity
FORC23_0067	COG0758	DNA mediated transformation
FORC23_0068	COG2922	Belongs to the Smg family
FORC23_0069	COG0551	DNA topoisomerase type I activity
FORC23_0070	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FORC23_0071	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FORC23_0072	COG0009	L-threonylcarbamoyladenylate synthase
FORC23_0073	COG0408	coproporphyrinogen oxidase activity
FORC23_0074	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FORC23_0076	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FORC23_0089	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FORC23_0090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FORC23_0091	COG0352	thiamine-phosphate diphosphorylase activity
FORC23_0092	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC23_0093	COG2104	thiamine diphosphate biosynthetic process
FORC23_0094	COG2022	thiamine diphosphate biosynthetic process
FORC23_0096	COG0006	proline dipeptidase activity
FORC23_0096	COG0006	proline dipeptidase activity
FORC23_0102	COG3220	belongs to the UPF0276 family
FORC23_0104	COG0210	DNA helicase
FORC23_0105	COG0405	Gamma-glutamyltransferase
FORC23_0106	COG1280	lysine exporter protein (LysE YggA)
FORC23_0108	COG2962	Rard protein
FORC23_0109	COG0514	ATP-dependent DNA helicase (RecQ)
FORC23_0111	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FORC23_0112	COG0248	Ppx GppA phosphatase
FORC23_0113	COG0513	Belongs to the DEAD box helicase family
FORC23_0114	COG3118	belongs to the thioredoxin family
FORC23_0115	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FORC23_0117	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FORC23_0120	COG3071	HemY protein
FORC23_0121	COG2959	enzyme of heme biosynthesis
FORC23_0122	COG1587	Uroporphyrinogen-III synthase
FORC23_0123	COG0181	hydroxymethylbilane synthase activity
FORC23_0124	COG3072	Adenylate cyclase
FORC23_0125	COG1965	Belongs to the frataxin family
FORC23_0126	COG0019	diaminopimelate decarboxylase activity
FORC23_0127	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FORC23_0129	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FORC23_0130	COG1011	Hydrolase
FORC23_0131	COG3287	FIST C domain
FORC23_0131	COG2200	EAL domain
FORC23_0131	COG2199	diguanylate cyclase activity
FORC23_0135	COG0561	phosphatase activity
FORC23_0136	COG2267	carboxylic ester hydrolase activity
FORC23_0137	COG1280	lysine exporter protein (LysE YggA)
FORC23_0138	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC23_0139	COG0640	Transcriptional regulator
FORC23_0140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC23_0150	COG2095	MarC family integral membrane protein
FORC23_0152	COG0742	ribosomal rna small subunit methyltransferase
FORC23_0153	COG0552	protein localization to endoplasmic reticulum
FORC23_0154	COG2884	Cell division ATP-binding protein ftsE
FORC23_0155	COG2177	Part of the ABC transporter FtsEX involved in
FORC23_0157	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC23_0158	COG0705	Rhomboid family
FORC23_0159	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC23_0160	COG3161	chorismate lyase activity
FORC23_0161	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FORC23_0162	COG2937	Belongs to the GPAT DAPAT family
FORC23_0163	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FORC23_0164	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FORC23_0165	COG0534	Mate efflux family protein
FORC23_0166	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC23_0169	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC23_0170	COG4206	TonB-dependent receptor
FORC23_0172	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FORC23_0174	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC23_0176	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FORC23_0179	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC23_0180	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC23_0181	COG0250	Participates in transcription elongation, termination and antitermination
FORC23_0182	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FORC23_0183	COG0081	regulation of translation
FORC23_0184	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FORC23_0185	COG0222	ribosome binding
FORC23_0186	COG0085	RNA polymerase activity
FORC23_0187	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FORC23_0188	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FORC23_0189	COG2816	NAD+ diphosphatase activity
FORC23_0192	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FORC23_0193	COG1573	uracil-dna glycosylase
FORC23_0194	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC23_0195	COG3068	Protein conserved in bacteria
FORC23_0196	COG1253	flavin adenine dinucleotide binding
FORC23_0199	COG0151	Belongs to the GarS family
FORC23_0200	COG0138	bifunctional purine biosynthesis protein purh
FORC23_0201	COG0789	Transcriptional regulator
FORC23_0202	COG3710	Transcriptional regulator
FORC23_0203	COG0531	amino acid
FORC23_0204	COG1982	Orn Lys Arg decarboxylase major
FORC23_0205	COG3706	GGDEF domain
FORC23_0206	COG0488	(ABC) transporter
FORC23_0207	COG2814	Major facilitator Superfamily
FORC23_0208	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FORC23_0209	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC23_0210	COG2264	protein methyltransferase activity
FORC23_0211	COG0439	Biotin carboxylase
FORC23_0212	COG0511	ligase activity, forming carbon-carbon bonds
FORC23_0213	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FORC23_0214	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC23_0217	COG2814	Major facilitator Superfamily
FORC23_0218	COG0784	Response regulator, receiver
FORC23_0218	COG2198	Histidine kinase
FORC23_0218	COG2205	protein histidine kinase activity
FORC23_0222	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC23_0224	COG3263	regulation of cellular component size
FORC23_0226	COG4232	protein-disulfide reductase activity
FORC23_0227	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC23_0228	COG1027	Aspartate ammonia-lyase
FORC23_0230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FORC23_0232	COG2205	protein histidine kinase activity
FORC23_0233	COG0745	RESPONSE REGULATOR receiver
FORC23_0234	COG3678	ATP-independent chaperone mediated protein folding
FORC23_0236	COG0205	6-phosphofructokinase activity
FORC23_0237	COG0534	Mate efflux family protein
FORC23_0238	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC23_0239	COG0459	protein refolding
FORC23_0242	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC23_0243	COG1509	lysine 2,3-aminomutase activity
FORC23_0244	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC23_0246	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC23_0247	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FORC23_0248	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC23_0249	COG1053	succinate dehydrogenase
FORC23_0250	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FORC23_0254	COG4942	peptidase
FORC23_0255	COG1045	serine acetyltransferase
FORC23_0256	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FORC23_0257	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FORC23_0258	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC23_0259	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FORC23_0262	COG0471	metal ion transport
FORC23_0263	COG0688	phosphatidylethanolamine metabolic process
FORC23_0264	COG1162	GTPase activity
FORC23_0265	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FORC23_0266	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FORC23_0267	COG0802	atpase or kinase
FORC23_0268	COG0860	N-Acetylmuramoyl-L-alanine amidase
FORC23_0269	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FORC23_0270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FORC23_0272	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FORC23_0273	COG0330	HflC and HflK could
FORC23_0274	COG0330	HflC and HflK could
FORC23_0275	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FORC23_0276	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FORC23_0277	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FORC23_0278	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC23_0278	COG1017	nitric oxide dioxygenase activity
FORC23_0279	COG1959	2 iron, 2 sulfur cluster binding
FORC23_0280	COG0557	exoribonuclease II activity
FORC23_0281	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC23_0282	COG0546	phosphoglycolate phosphatase activity
FORC23_0283	COG0180	Tryptophanyl-tRNA synthetase
FORC23_0286	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC23_0287	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FORC23_0289	COG1012	belongs to the aldehyde dehydrogenase family
FORC23_0291	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC23_0292	COG3954	Phosphoribulokinase
FORC23_0293	COG3089	Belongs to the UPF0270 family
FORC23_0294	COG0429	hydrolase of the alpha beta-hydrolase fold
FORC23_0296	COG0488	(ABC) transporter
FORC23_0297	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC23_0300	COG1047	Peptidyl-prolyl cis-trans
FORC23_0301	COG1446	asparaginase
FORC23_0302	COG2900	Belongs to the SlyX family
FORC23_0304	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC23_0305	COG2964	Protein conserved in bacteria
FORC23_0306	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FORC23_0307	COG2923	Belongs to the DsrF TusC family
FORC23_0310	COG0049	tRNA binding
FORC23_0311	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC23_0312	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FORC23_0313	COG2906	2 iron, 2 sulfur cluster binding
FORC23_0315	COG0281	malic enzyme
FORC23_0317	COG0626	cystathionine gamma-synthase activity
FORC23_0318	COG0460	homoserine dehydrogenase
FORC23_0318	COG0527	aspartate kinase activity
FORC23_0319	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FORC23_0321	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FORC23_0322	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC23_0323	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FORC23_0324	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC23_0325	COG0137	argininosuccinate synthase activity
FORC23_0326	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC23_0326	COG0165	Argininosuccinate lyase
FORC23_0328	COG0678	peroxiredoxin activity
FORC23_0328	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC23_0330	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FORC23_0336	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FORC23_0337	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FORC23_0339	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FORC23_0340	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FORC23_0341	COG0360	Binds together with S18 to 16S ribosomal RNA
FORC23_0342	COG2965	DNA replication, synthesis of RNA primer
FORC23_0344	COG0359	binds to the 23S rRNA
FORC23_0346	COG0305	Participates in initiation and elongation during chromosome replication
FORC23_0347	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC23_0349	COG0432	Pfam Uncharacterised protein family UPF0047
FORC23_0350	COG0166	Belongs to the GPI family
FORC23_0352	COG0735	belongs to the Fur family
FORC23_0353	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC23_0357	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FORC23_0358	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC23_0359	COG0175	sulfate reduction
FORC23_0360	COG3335	DDE superfamily endonuclease
FORC23_0362	COG1410	methionine synthase
FORC23_0362	COG0646	methionine synthase
FORC23_0363	COG0527	aspartate kinase activity
FORC23_0364	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FORC23_0366	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FORC23_0369	COG0629	single-stranded DNA binding
FORC23_0370	COG2200	EAL domain
FORC23_0370	COG2199	diguanylate cyclase activity
FORC23_0375	COG3409	Peptidoglycan-binding domain 1 protein
FORC23_0375	COG3267	Type II secretory pathway component ExeA
FORC23_0377	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC23_0378	COG1459	type II secretion system
FORC23_0387	COG1077	Cell shape determining protein MreB Mrl
FORC23_0388	COG1792	Involved in formation and maintenance of cell shape
FORC23_0389	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FORC23_0390	COG0424	maF-like protein
FORC23_0391	COG1530	ribonuclease E activity
FORC23_0392	COG3164	Protein of unknown function
FORC23_0393	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC23_0394	COG0312	modulator of DNA gyrase
FORC23_0395	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FORC23_0396	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FORC23_0398	COG0564	pseudouridine synthase activity
FORC23_0399	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC23_0400	COG3028	Belongs to the UPF0307 family
FORC23_0401	COG0312	modulator of DNA gyrase
FORC23_0402	COG2239	Acts as a magnesium transporter
FORC23_0403	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC23_0404	COG1660	Displays ATPase and GTPase activities
FORC23_0405	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC23_0406	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC23_0408	COG1137	ATPase activity
FORC23_0409	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FORC23_0411	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FORC23_0411	COG0517	IMP dehydrogenase activity
FORC23_0413	COG1127	ABC transporter
FORC23_0414	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FORC23_0415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC23_0416	COG2854	intermembrane phospholipid transfer
FORC23_0418	COG5007	Belongs to the BolA IbaG family
FORC23_0419	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FORC23_0420	COG0204	Acyl-transferase
FORC23_0421	COG0251	oxidation-reduction process
FORC23_0422	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FORC23_0423	COG0540	Belongs to the ATCase OTCase family
FORC23_0424	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FORC23_0425	COG2235	arginine
FORC23_0430	COG0525	valine-tRNA ligase activity
FORC23_0431	COG2927	DNA polymerase III (CHI subunit)
FORC23_0432	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC23_0433	COG0795	lipopolysaccharide-transporting ATPase activity
FORC23_0434	COG0795	lipopolysaccharide-transporting ATPase activity
FORC23_0436	COG4325	translation initiation factor activity
FORC23_0437	COG1028	Short-chain dehydrogenase reductase Sdr
FORC23_0438	COG0726	polysaccharide deacetylase
FORC23_0439	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC23_0440	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC23_0441	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC23_0442	COG1486	melibiose metabolic process
FORC23_0443	COG3394	polysaccharide catabolic process
FORC23_0445	COG3437	response regulator, receiver
FORC23_0446	COG1012	belongs to the aldehyde dehydrogenase family
FORC23_0448	COG0741	lytic transglycosylase activity
FORC23_0449	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FORC23_0451	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FORC23_0453	COG2066	Belongs to the glutaminase family
FORC23_0454	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC23_0455	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FORC23_0457	COG1872	DUF167
FORC23_0458	COG0762	integral membrane protein
FORC23_0459	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FORC23_0460	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FORC23_0463	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FORC23_0464	COG1678	Uncharacterized ACR, COG1678
FORC23_0465	COG0189	ligase activity
FORC23_0466	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FORC23_0467	COG2356	endonuclease I
FORC23_0468	COG3091	SprT-like family
FORC23_0470	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FORC23_0471	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC23_0472	COG0583	DNA-binding transcription factor activity
FORC23_0473	COG4771	TonB-dependent receptor
FORC23_0474	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC23_0475	COG0126	phosphoglycerate kinase activity
FORC23_0476	COG0191	fructose-bisphosphate aldolase activity
FORC23_0477	COG0668	transmembrane transport
FORC23_0478	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FORC23_0480	COG0583	DNA-binding transcription factor activity
FORC23_0482	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC23_0483	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FORC23_0484	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FORC23_0485	COG3079	Belongs to the UPF0149 family
FORC23_0486	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC23_0487	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC23_0490	COG0354	folic acid binding
FORC23_0491	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FORC23_0492	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FORC23_0493	COG1595	DNA-templated transcription, initiation
FORC23_0494	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FORC23_0496	COG3086	response to oxidative stress
FORC23_0497	COG0481	GTPase activity
FORC23_0498	COG0681	Belongs to the peptidase S26 family
FORC23_0499	COG0571	ribonuclease III activity
FORC23_0500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FORC23_0501	COG1381	Involved in DNA repair and RecF pathway recombination
FORC23_0502	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FORC23_0503	COG0736	holo-[acyl-carrier-protein] synthase activity
FORC23_0505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FORC23_0506	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC23_0507	COG3956	TIGRFAM MazG family protein
FORC23_0508	COG0504	CTP synthase activity
FORC23_0509	COG0148	phosphopyruvate hydratase activity
FORC23_0510	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FORC23_0511	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FORC23_0512	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FORC23_0513	COG0585	pseudouridine synthase activity
FORC23_0514	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FORC23_0515	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FORC23_0517	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC23_0518	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FORC23_0519	COG1546	Belongs to the CinA family
FORC23_0520	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FORC23_0521	COG2137	regulation of response to DNA damage stimulus
FORC23_0522	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FORC23_0523	COG0527	aspartate kinase activity
FORC23_0525	COG3630	sodium ion export across plasma membrane
FORC23_0526	COG0511	ligase activity, forming carbon-carbon bonds
FORC23_0526	COG5016	pyruvate
FORC23_0527	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FORC23_0528	COG1063	alcohol dehydrogenase
FORC23_0529	COG1238	metal cluster binding
FORC23_0530	COG0612	Peptidase, M16
FORC23_0531	COG2918	glutathione biosynthetic process
FORC23_0533	COG1854	S-ribosylhomocysteine lyase activity
FORC23_0534	COG4536	flavin adenine dinucleotide binding
FORC23_0535	COG4137	Cytochrome C assembly protein
FORC23_0536	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FORC23_0537	COG0228	four-way junction DNA binding
FORC23_0538	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FORC23_0539	COG0336	Belongs to the RNA methyltransferase TrmD family
FORC23_0540	COG0335	large ribosomal subunit rRNA binding
FORC23_0541	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FORC23_0542	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FORC23_0543	COG0237	dephospho-CoA kinase activity
FORC23_0545	COG1459	type II secretion system
FORC23_0546	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC23_0548	COG0157	Belongs to the NadC ModD family
FORC23_0550	COG2186	Transcriptional regulator
FORC23_0551	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FORC23_0552	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC23_0553	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC23_0556	COG0288	reversible hydration of carbon dioxide
FORC23_0557	COG0659	secondary active sulfate transmembrane transporter activity
FORC23_0558	COG1131	(ABC) transporter
FORC23_0559	COG0842	Transport permease protein
FORC23_0560	COG1560	Kdo2-lipid A biosynthetic process
FORC23_0561	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FORC23_0562	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FORC23_0563	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC23_0565	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC23_0566	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC23_0567	COG1489	DNA binding
FORC23_0568	COG1643	Atp-dependent helicase
FORC23_0569	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC23_0570	COG1752	Esterase of the alpha-beta hydrolase superfamily
FORC23_0571	COG1049	propionate catabolic process, 2-methylcitrate cycle
FORC23_0572	COG3112	Uncharacterised protein family (UPF0231)
FORC23_0574	COG0004	ammonium transporteR
FORC23_0575	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC23_0577	COG3842	ATPase activity
FORC23_0578	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC23_0581	COG2971	BadF BadG BcrA BcrD
FORC23_0583	COG4608	Belongs to the ABC transporter superfamily
FORC23_0584	COG0444	Belongs to the ABC transporter superfamily
FORC23_0585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC23_0587	COG0747	negative chemotaxis
FORC23_0588	COG2198	Histidine kinase
FORC23_0588	COG2205	protein histidine kinase activity
FORC23_0588	COG0784	Response regulator, receiver
FORC23_0588	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC23_0589	COG2813	Specifically methylates the guanine in position
FORC23_0590	COG0628	permease
FORC23_0592	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FORC23_0593	COG0316	Belongs to the HesB IscA family
FORC23_0595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC23_0596	COG0739	heme binding
FORC23_0597	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC23_0599	COG2027	D-alanyl-D-alanine carboxypeptidase
FORC23_0600	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC23_0601	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC23_0602	COG1534	Rna-binding protein
FORC23_0603	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FORC23_0604	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FORC23_0605	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FORC23_0606	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC23_0607	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FORC23_0608	COG0779	Required for maturation of 30S ribosomal subunits
FORC23_0609	COG0195	Participates in both transcription termination and antitermination
FORC23_0610	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FORC23_0611	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FORC23_0612	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FORC23_0613	COG1185	polyribonucleotide nucleotidyltransferase activity
FORC23_0614	COG4785	May be involved in cell division
FORC23_0616	COG0534	Mate efflux family protein
FORC23_0621	COG3153	acetyltransferase
FORC23_0625	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FORC23_0627	COG0084	hydrolase, TatD family'
FORC23_0628	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC23_0629	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FORC23_0630	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FORC23_0631	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FORC23_0632	COG0813	purine-nucleoside phosphorylase activity
FORC23_0634	COG0560	Phosphoserine phosphatase
FORC23_0636	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FORC23_0637	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC23_0638	COG0583	DNA-binding transcription factor activity
FORC23_0640	COG1022	Amp-dependent synthetase and ligase
FORC23_0641	COG2169	Transcriptional regulator
FORC23_0646	COG4964	Belongs to the GSP D family
FORC23_0658	COG0583	DNA-binding transcription factor activity
FORC23_0659	COG0531	amino acid
FORC23_0660	COG2731	YhcH YjgK YiaL family protein
FORC23_0661	COG3250	beta-galactosidase activity
FORC23_0662	COG1609	Transcriptional regulator
FORC23_0663	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC23_0664	COG1085	galactose-1-phosphate uridylyltransferase
FORC23_0665	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FORC23_0666	COG2017	converts alpha-aldose to the beta-anomer
FORC23_0669	COG2211	Major facilitator Superfamily
FORC23_0670	COG1609	Transcriptional regulator
FORC23_0671	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC23_0675	COG0598	Magnesium transport protein CorA
FORC23_0676	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FORC23_0677	COG1349	DNA-binding transcription factor activity
FORC23_0678	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FORC23_0679	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC23_0680	COG2271	Major facilitator Superfamily
FORC23_0681	COG0584	glycerophosphoryl diester phosphodiesterase
FORC23_0682	COG2171	N-acyltransferase activity
FORC23_0683	COG3141	response to X-ray
FORC23_0687	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FORC23_0688	COG1074	ATP-dependent DNA helicase activity
FORC23_0689	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FORC23_0691	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FORC23_0691	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FORC23_0693	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FORC23_0694	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FORC23_0695	COG2166	iron-sulfur cluster assembly
FORC23_0696	COG3706	GGDEF domain
FORC23_0697	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FORC23_0698	COG0693	protein deglycase activity
FORC23_0699	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FORC23_0703	COG1595	DNA-templated transcription, initiation
FORC23_0707	COG3056	Lipoprotein
FORC23_0708	COG2813	Specifically methylates the guanine in position
FORC23_0709	COG0271	Belongs to the BolA IbaG family
FORC23_0711	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC23_0712	COG1805	sodium ion transport
FORC23_0713	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC23_0714	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC23_0715	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FORC23_0716	COG2871	sodium ion transport
FORC23_0717	COG1477	protein flavinylation
FORC23_0720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FORC23_0721	COG0514	ATP-dependent DNA helicase (RecQ)
FORC23_0722	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC23_0725	COG0733	neurotransmitter:sodium symporter activity
FORC23_0729	COG0442	prolyl-tRNA aminoacylation
FORC23_0730	COG1720	tRNA m6t6A37 methyltransferase activity
FORC23_0731	COG0254	rRNA binding
FORC23_0732	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC23_0733	COG1671	Belongs to the UPF0178 family
FORC23_0737	COG3098	single-species biofilm formation
FORC23_0738	COG0564	pseudouridine synthase activity
FORC23_0740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FORC23_0741	COG0024	Methionine aminopeptidase
FORC23_0742	COG0052	Belongs to the universal ribosomal protein uS2 family
FORC23_0743	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FORC23_0744	COG0528	UMP kinase activity
FORC23_0745	COG0233	cytoplasmic translational termination
FORC23_0746	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FORC23_0747	COG0575	Belongs to the CDS family
FORC23_0748	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FORC23_0749	COG0750	zinc metalloprotease
FORC23_0751	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FORC23_0752	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC23_0753	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC23_0754	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC23_0755	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC23_0756	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FORC23_0757	COG0587	DNA-directed DNA polymerase activity
FORC23_0758	COG0825	malonyl-CoA metabolic process
FORC23_0759	COG0037	tRNA processing
FORC23_0761	COG0347	Belongs to the P(II) protein family
FORC23_0762	COG3021	interspecies interaction between organisms
FORC23_0764	COG0741	lytic transglycosylase activity
FORC23_0764	COG1388	LysM domain
FORC23_0765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC23_0766	COG2226	methyltransferase
FORC23_0767	COG0328	RNA-DNA hybrid ribonuclease activity
FORC23_0768	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC23_0772	COG0456	acetyltransferase
FORC23_0774	COG1960	acyl-CoA dehydrogenase activity
FORC23_0775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC23_0776	COG0121	glutamine amidotransferase
FORC23_0777	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FORC23_0778	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FORC23_0779	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FORC23_0780	COG2233	PERMEase
FORC23_0784	COG1393	Belongs to the ArsC family
FORC23_0785	COG4783	chaperone-mediated protein folding
FORC23_0788	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FORC23_0789	COG2716	regulation of RNA biosynthetic process
FORC23_0790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC23_0794	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC23_0795	COG1393	Belongs to the ArsC family
FORC23_0800	COG2837	iron assimilation
FORC23_0801	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC23_0802	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC23_0803	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC23_0804	COG1334	flagellar protein FlaG
FORC23_0805	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC23_0807	COG1516	flagellar protein fliS
FORC23_0809	COG2204	response regulator
FORC23_0810	COG1677	Flagellar hook-basal body complex protein FliE
FORC23_0812	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC23_0822	COG1987	bacterial-type flagellum assembly
FORC23_0823	COG1684	flagellar biosynthetic protein fliR
FORC23_0827	COG0455	bacterial-type flagellum organization
FORC23_0830	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FORC23_0831	COG2198	Histidine kinase
FORC23_0831	COG0643	Histidine kinase
FORC23_0832	COG2201	protein-glutamate methylesterase activity
FORC23_0833	COG1192	Involved in chromosome partitioning
FORC23_0835	COG0835	chemotaxis
FORC23_0837	COG4133	protoheme IX ABC transporter activity
FORC23_0838	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC23_0839	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC23_0840	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FORC23_0841	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FORC23_0842	COG1138	Cytochrome C-type biogenesis protein
FORC23_0843	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FORC23_0846	COG2853	Lipoprotein
FORC23_0848	COG2067	long-chain fatty acid transport protein
FORC23_0851	COG0183	Belongs to the thiolase family
FORC23_0852	COG1024	Enoyl-CoA hydratase
FORC23_0852	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC23_0855	COG2062	phosphohistidine phosphatase, SixA
FORC23_0856	COG2840	Smr protein MutS2
FORC23_0857	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC23_0858	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FORC23_0859	COG2860	membrane
FORC23_0860	COG3101	peptidyl-lysine hydroxylation
FORC23_0862	COG0431	NADPH-dependent FMN reductase
FORC23_0863	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC23_0863	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FORC23_0864	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC23_0865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FORC23_0866	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC23_0868	COG0101	tRNA pseudouridine synthase activity
FORC23_0869	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC23_0870	COG0285	dihydrofolate synthase activity
FORC23_0871	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FORC23_0872	COG1286	toxin biosynthetic process
FORC23_0873	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FORC23_0874	COG0583	DNA-binding transcription factor activity
FORC23_0875	COG0745	RESPONSE REGULATOR receiver
FORC23_0876	COG2832	Protein of unknown function (DUF454)
FORC23_0877	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FORC23_0879	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FORC23_0880	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FORC23_0881	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FORC23_0882	COG0814	amino acid
FORC23_0883	COG0251	oxidation-reduction process
FORC23_0884	COG3681	Belongs to the UPF0597 family
FORC23_0887	COG2261	transglycosylase associated protein
FORC23_0888	COG2983	Belongs to the UPF0260 family
FORC23_0889	COG0668	transmembrane transport
FORC23_0890	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FORC23_0891	COG0346	lactoylglutathione lyase activity
FORC23_0893	COG1785	Belongs to the alkaline phosphatase family
FORC23_0896	COG2226	methyltransferase
FORC23_0899	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FORC23_0900	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC23_0902	COG3139	Protein of unknown function (DUF1315)
FORC23_0903	COG0252	asparaginase activity
FORC23_0904	COG0616	signal peptide processing
FORC23_0905	COG1902	pentaerythritol trinitrate reductase activity
FORC23_0905	COG0446	pyridine nucleotide-disulphide oxidoreductase
FORC23_0906	COG0778	Nitroreductase
FORC23_0907	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC23_0910	COG0123	including yeast histone deacetylase and acetoin utilization protein
FORC23_0911	COG3083	sulfuric ester hydrolase activity
FORC23_0912	COG3082	Protein of unknown function (DUF1414)
FORC23_0913	COG3081	Nucleoid-associated protein
FORC23_0916	COG1757	Na H antiporter
FORC23_0917	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FORC23_0918	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC23_0919	COG2095	MarC family integral membrane protein
FORC23_0920	COG1012	belongs to the aldehyde dehydrogenase family
FORC23_0920	COG1454	alcohol dehydrogenase
FORC23_0924	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FORC23_0926	COG2056	Na+-H+ antiporter family
FORC23_0927	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FORC23_0928	COG2885	chlorophyll binding
FORC23_0930	COG0346	lactoylglutathione lyase activity
FORC23_0931	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FORC23_0932	COG4660	Part of a membrane complex involved in electron transport
FORC23_0933	COG4659	FMN binding
FORC23_0934	COG4658	electron transport chain
FORC23_0935	COG4656	Part of a membrane complex involved in electron transport
FORC23_0936	COG2878	Part of a membrane complex involved in electron transport
FORC23_0937	COG4657	Part of a membrane complex involved in electron transport
FORC23_0938	COG0556	nucleotide-excision repair
FORC23_0939	COG2204	response regulator
FORC23_0940	COG2198	Histidine kinase
FORC23_0941	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FORC23_0942	COG0521	Mo-molybdopterin cofactor biosynthetic process
FORC23_0943	COG0315	cyclic pyranopterin monophosphate synthase activity
FORC23_0944	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FORC23_0945	COG0314	molybdopterin synthase activity
FORC23_0947	COG0601	transmembrane transport
FORC23_0948	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC23_0949	COG0444	Belongs to the ABC transporter superfamily
FORC23_0951	COG0435	Glutathione S-transferase
FORC23_0953	COG3174	membrane
FORC23_0954	COG0280	phosphate acetyltransferase
FORC23_0954	COG0857	belongs to the CobB CobQ family
FORC23_0955	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC23_0956	COG3092	negative regulation of chromosome organization
FORC23_0958	COG4120	Belongs to the binding-protein-dependent transport system permease family
FORC23_0959	COG1122	ATPase activity
FORC23_0960	COG0366	Alpha amylase catalytic
FORC23_0961	COG3706	GGDEF domain
FORC23_0961	COG0745	RESPONSE REGULATOR receiver
FORC23_0962	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FORC23_0963	COG0653	protein targeting
FORC23_0964	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FORC23_0965	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC23_0966	COG2186	Transcriptional regulator
FORC23_0968	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC23_0968	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC23_0969	COG0489	protein tyrosine kinase activity
FORC23_0970	COG0572	uridine kinase
FORC23_0972	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FORC23_0973	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC23_0974	COG0659	secondary active sulfate transmembrane transporter activity
FORC23_0975	COG1530	ribonuclease E activity
FORC23_0976	COG0564	pseudouridine synthase activity
FORC23_0977	COG0424	maF-like protein
FORC23_0978	COG1399	metal-binding, possibly nucleic acid-binding protein
FORC23_0980	COG0416	fatty acid biosynthetic process
FORC23_0981	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC23_0987	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FORC23_0988	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FORC23_0990	COG0084	hydrolase, TatD family'
FORC23_0991	COG1263	PTS System
FORC23_0991	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC23_0993	COG0733	neurotransmitter:sodium symporter activity
FORC23_0995	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC23_0996	COG0469	pyruvate kinase activity
FORC23_0997	COG1940	carbohydrate kinase activity
FORC23_0998	COG0784	Response regulator, receiver
FORC23_0998	COG0835	chemotaxis
FORC23_0999	COG0587	DNA-directed DNA polymerase activity
FORC23_1002	COG1028	Short-chain dehydrogenase reductase Sdr
FORC23_1003	COG0616	signal peptide processing
FORC23_1004	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FORC23_1005	COG0539	negative regulation of cytoplasmic translation
FORC23_1007	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FORC23_1008	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FORC23_1009	COG0284	orotidine-5'-phosphate decarboxylase activity
FORC23_1010	COG4166	transmembrane transport
FORC23_1013	COG0463	Glycosyl transferase, family 2
FORC23_1015	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FORC23_1017	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FORC23_1017	COG3008	intermembrane lipid transfer
FORC23_1018	COG2995	paraquat-inducible protein a
FORC23_1019	COG3258	Cytochrome c
FORC23_1020	COG2863	cytochrome
FORC23_1028	COG4232	protein-disulfide reductase activity
FORC23_1029	COG3118	belongs to the thioredoxin family
FORC23_1033	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC23_1035	COG0577	efflux transmembrane transporter activity
FORC23_1035	COG1136	(ABC) transporter
FORC23_1036	COG1136	(ABC) transporter
FORC23_1036	COG0577	efflux transmembrane transporter activity
FORC23_1037	COG1136	(ABC) transporter
FORC23_1037	COG0577	efflux transmembrane transporter activity
FORC23_1038	COG1335	isochorismatase
FORC23_1041	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC23_1048	COG3850	Histidine kinase
FORC23_1048	COG5002	protein histidine kinase activity
FORC23_1049	COG0745	RESPONSE REGULATOR receiver
FORC23_1050	COG0840	transmembrane signaling receptor activity
FORC23_1051	COG1032	radical SAM domain protein
FORC23_1052	COG2203	Gaf domain
FORC23_1052	COG5001	Diguanylate cyclase
FORC23_1052	COG4251	negative regulation of phosphorylation
FORC23_1052	COG3706	GGDEF domain
FORC23_1055	COG0583	DNA-binding transcription factor activity
FORC23_1056	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FORC23_1058	COG2350	Protein conserved in bacteria
FORC23_1059	COG1607	acyl-coa hydrolase
FORC23_1060	COG2917	probably involved in intracellular septation
FORC23_1064	COG1301	dicarboxylic acid transport
FORC23_1065	COG0318	PFAM AMP-dependent synthetase and ligase
FORC23_1066	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC23_1067	COG0159	tryptophan synthase activity
FORC23_1068	COG0133	tryptophan synthase activity
FORC23_1069	COG0135	phosphoribosylanthranilate isomerase activity
FORC23_1069	COG0134	indole-3-glycerol-phosphate synthase activity
FORC23_1070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FORC23_1071	COG0512	Glutamine amidotransferase of anthranilate synthase
FORC23_1072	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC23_1073	COG0613	PHP domain protein
FORC23_1074	COG0009	L-threonylcarbamoyladenylate synthase
FORC23_1076	COG1187	pseudouridine synthase activity
FORC23_1077	COG3099	Belongs to the UPF0263 family
FORC23_1078	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FORC23_1080	COG0417	DNA replication proofreading
FORC23_1081	COG2197	response regulator
FORC23_1082	COG0322	excinuclease ABC activity
FORC23_1086	COG0019	diaminopimelate decarboxylase activity
FORC23_1091	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC23_1092	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FORC23_1093	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC23_1097	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FORC23_1099	COG0437	4 iron, 4 sulfur cluster binding
FORC23_1100	COG3301	Polysulphide reductase, NrfD
FORC23_1101	COG1138	Cytochrome C-type biogenesis protein
FORC23_1103	COG4235	cytochrome complex assembly
FORC23_1103	COG3088	subunit of a heme lyase
FORC23_1104	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC23_1109	COG2989	Protein conserved in bacteria
FORC23_1110	COG3108	Peptidase M15
FORC23_1111	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FORC23_1114	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FORC23_1119	COG1846	Transcriptional regulator
FORC23_1120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC23_1121	COG0840	transmembrane signaling receptor activity
FORC23_1125	COG1448	Aminotransferase
FORC23_1128	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC23_1130	COG0017	Asparaginyl-tRNA synthetase
FORC23_1131	COG0840	transmembrane signaling receptor activity
FORC23_1132	COG0720	synthase
FORC23_1134	COG2200	EAL domain
FORC23_1135	COG1760	l-serine dehydratase
FORC23_1136	COG0814	amino acid
FORC23_1137	COG0494	nUDIX hydrolase
FORC23_1139	COG2205	protein histidine kinase activity
FORC23_1139	COG0784	Response regulator, receiver
FORC23_1140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FORC23_1143	COG3106	COG3106 Predicted ATPase
FORC23_1144	COG3768	UPF0283 membrane protein
FORC23_1146	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC23_1160	COG0456	acetyltransferase
FORC23_1161	COG0251	oxidation-reduction process
FORC23_1189	COG0582	viral genome integration into host DNA
FORC23_1218	COG0582	viral genome integration into host DNA
FORC23_1238	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC23_1239	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC23_1254	COG0346	lactoylglutathione lyase activity
FORC23_1264	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FORC23_1265	COG0583	DNA-binding transcription factor activity
FORC23_1272	COG0471	metal ion transport
FORC23_1273	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC23_1273	COG4191	Histidine kinase
FORC23_1275	COG5001	Diguanylate cyclase
FORC23_1275	COG3300	MHYT domain
FORC23_1277	COG1280	lysine exporter protein (LysE YggA)
FORC23_1278	COG1328	CTP reductase activity
FORC23_1279	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC23_1281	COG0861	Integral membrane protein TerC family
FORC23_1283	COG1368	sulfuric ester hydrolase activity
FORC23_1284	COG0642	Histidine kinase
FORC23_1285	COG0745	RESPONSE REGULATOR receiver
FORC23_1287	COG1028	Short-chain dehydrogenase reductase Sdr
FORC23_1289	COG1022	Amp-dependent synthetase and ligase
FORC23_1291	COG2113	Glycine betaine
FORC23_1292	COG4176	ABC-type proline glycine betaine transport system permease component
FORC23_1296	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC23_1297	COG0456	acetyltransferase
FORC23_1298	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC23_1299	COG0662	Cupin 2, conserved barrel domain protein
FORC23_1300	COG0527	aspartate kinase activity
FORC23_1301	COG1858	cytochrome C peroxidase
FORC23_1304	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC23_1307	COG3290	protein histidine kinase activity
FORC23_1308	COG4565	transcriptional regulatory protein
FORC23_1309	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FORC23_1310	COG0363	glucosamine-6-phosphate deaminase activity
FORC23_1311	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FORC23_1313	COG3284	Transcriptional regulator
FORC23_1314	COG1012	belongs to the aldehyde dehydrogenase family
FORC23_1328	COG4669	(LipO)protein
FORC23_1332	COG3177	Filamentation induced by cAMP protein fic
FORC23_1338	COG1073	alpha beta
FORC23_1339	COG1073	alpha beta
FORC23_1341	COG4792	protein secretion
FORC23_1342	COG4791	protein targeting
FORC23_1343	COG4794	Type iii secretion
FORC23_1344	COG4790	Type iii secretion
FORC23_1345	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC23_1358	COG0457	Tetratricopeptide repeat
FORC23_1362	COG0730	response to heat
FORC23_1368	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FORC23_1369	COG0372	Belongs to the citrate synthase family
FORC23_1371	COG2828	Protein conserved in bacteria
FORC23_1376	COG0561	phosphatase activity
FORC23_1377	COG0602	queuosine metabolic process
FORC23_1378	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FORC23_1379	COG3706	GGDEF domain
FORC23_1387	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC23_1388	COG0840	transmembrane signaling receptor activity
FORC23_1389	COG1254	Belongs to the acylphosphatase family
FORC23_1390	COG2920	part of a sulfur-relay system
FORC23_1392	COG0670	Belongs to the BI1 family
FORC23_1393	COG1126	abc transporter atp-binding protein
FORC23_1394	COG0765	amino acid transport
FORC23_1395	COG4597	amino acid ABC transporter
FORC23_1396	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC23_1398	COG1666	GTP binding
FORC23_1399	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC23_1403	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FORC23_1403	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FORC23_1404	COG3008	intermembrane lipid transfer
FORC23_1405	COG2995	paraquat-inducible protein a
FORC23_1406	COG1132	(ABC) transporter
FORC23_1407	COG1956	GAF domain-containing protein
FORC23_1408	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FORC23_1411	COG0308	aminopeptidase N
FORC23_1412	COG2902	Dehydrogenase
FORC23_1413	COG0167	dihydroorotate dehydrogenase activity
FORC23_1415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FORC23_1415	COG0116	Belongs to the methyltransferase superfamily
FORC23_1420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC23_1421	COG1067	ATP-dependent peptidase activity
FORC23_1422	COG3120	sequence-specific DNA binding
FORC23_1428	COG3278	Belongs to the heme-copper respiratory oxidase family
FORC23_1431	COG2010	Cytochrome c
FORC23_1433	COG2217	Heavy metal translocating P-type atpase
FORC23_1436	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FORC23_1437	COG0589	response to stress
FORC23_1438	COG0037	tRNA processing
FORC23_1442	COG3842	ATPase activity
FORC23_1443	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC23_1444	COG1177	transmembrane transport
FORC23_1445	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC23_1446	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC23_1447	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FORC23_1449	COG0004	ammonium transporteR
FORC23_1450	COG4282	regulation of fungal-type cell wall biogenesis
FORC23_1454	COG0437	4 iron, 4 sulfur cluster binding
FORC23_1455	COG3383	formate dehydrogenase (NAD+) activity
FORC23_1455	COG0243	molybdopterin cofactor binding
FORC23_1461	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC23_1462	COG0488	(ABC) transporter
FORC23_1463	COG4191	Histidine kinase
FORC23_1464	COG2204	response regulator
FORC23_1467	COG3842	ATPase activity
FORC23_1468	COG0746	molybdenum cofactor guanylyltransferase activity
FORC23_1471	COG1940	carbohydrate kinase activity
FORC23_1479	COG0840	transmembrane signaling receptor activity
FORC23_1479	COG3290	protein histidine kinase activity
FORC23_1480	COG0791	NLP P60 protein
FORC23_1482	COG3706	GGDEF domain
FORC23_1483	COG2201	protein-glutamate methylesterase activity
FORC23_1486	COG0307	riboflavin synthase, alpha
FORC23_1487	COG0534	Mate efflux family protein
FORC23_1489	COG1793	dna ligase
FORC23_1495	COG2204	response regulator
FORC23_1503	COG0438	transferase activity, transferring glycosyl groups
FORC23_1504	COG1215	transferase activity, transferring glycosyl groups
FORC23_1506	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC23_1509	COG1643	Atp-dependent helicase
FORC23_1510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FORC23_1511	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC23_1511	COG2221	Nitrite and sulphite reductase 4Fe-4S
FORC23_1513	COG3302	dmso reductase anchor subunit
FORC23_1514	COG0437	4 iron, 4 sulfur cluster binding
FORC23_1515	COG0243	molybdopterin cofactor binding
FORC23_1521	COG3706	GGDEF domain
FORC23_1523	COG0443	Heat shock 70 kDa protein
FORC23_1524	COG0443	Heat shock 70 kDa protein
FORC23_1529	COG1132	(ABC) transporter
FORC23_1530	COG1132	(ABC) transporter
FORC23_1534	COG0814	amino acid
FORC23_1536	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FORC23_1541	COG1115	amino acid carrier protein
FORC23_1543	COG1280	lysine exporter protein (LysE YggA)
FORC23_1544	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FORC23_1545	COG1560	Kdo2-lipid A biosynthetic process
FORC23_1546	COG0531	amino acid
FORC23_1548	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FORC23_1549	COG3063	Type IV pilus biogenesis stability protein PilW
FORC23_1552	COG2205	protein histidine kinase activity
FORC23_1552	COG3437	response regulator, receiver
FORC23_1552	COG3850	Histidine kinase
FORC23_1552	COG4999	Histidine kinase
FORC23_1555	COG0110	maltose O-acetyltransferase activity
FORC23_1559	COG2315	Protein conserved in bacteria
FORC23_1560	COG1846	Transcriptional regulator
FORC23_1565	COG2771	luxR family
FORC23_1565	COG2200	EAL domain
FORC23_1566	COG1227	inorganic diphosphatase activity
FORC23_1567	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FORC23_1568	COG1012	belongs to the aldehyde dehydrogenase family
FORC23_1569	COG2957	Belongs to the agmatine deiminase family
FORC23_1571	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC23_1572	COG1012	belongs to the aldehyde dehydrogenase family
FORC23_1573	COG1396	sequence-specific DNA binding
FORC23_1573	COG1917	Cupin 2, conserved barrel domain protein
FORC23_1574	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FORC23_1575	COG0174	glutamine synthetase
FORC23_1576	COG1757	Na H antiporter
FORC23_1580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC23_1581	COG1280	lysine exporter protein (LysE YggA)
FORC23_1587	COG0625	glutathione transferase activity
FORC23_1589	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FORC23_1591	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC23_1595	COG0813	purine-nucleoside phosphorylase activity
FORC23_1597	COG0601	transmembrane transport
FORC23_1598	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC23_1599	COG0444	Belongs to the ABC transporter superfamily
FORC23_1602	COG3291	Pkd domain containing protein
FORC23_1604	COG1177	transmembrane transport
FORC23_1605	COG1176	ABC-type spermidine putrescine transport system, permease component I
FORC23_1606	COG3842	ATPase activity
FORC23_1607	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FORC23_1608	COG2423	ornithine cyclodeaminase activity
FORC23_1611	COG3938	Belongs to the proline racemase family
FORC23_1617	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FORC23_1618	COG3475	LICD family
FORC23_1619	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FORC23_1620	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FORC23_1624	COG0583	DNA-binding transcription factor activity
FORC23_1628	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FORC23_1629	COG4139	cobalamin transport
FORC23_1630	COG2988	succinylglutamate desuccinylase activity
FORC23_1632	COG2062	phosphohistidine phosphatase, SixA
FORC23_1634	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FORC23_1635	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FORC23_1636	COG0702	epimerase
FORC23_1638	COG2925	Exonuclease
FORC23_1639	COG1346	cytolysis
FORC23_1640	COG0295	cytidine deaminase activity
FORC23_1641	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FORC23_1642	COG0500	methyltransferase
FORC23_1644	COG0776	regulation of translation
FORC23_1646	COG0072	phenylalanine-tRNA ligase activity
FORC23_1646	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FORC23_1647	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FORC23_1648	COG3706	GGDEF domain
FORC23_1654	COG0393	Putative heavy-metal-binding
FORC23_1656	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FORC23_1658	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FORC23_1661	COG2188	Transcriptional regulator
FORC23_1662	COG1228	amidohydrolase
FORC23_1663	COG0010	Belongs to the arginase family
FORC23_1664	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FORC23_1665	COG2986	histidine ammonia-lyase
FORC23_1668	COG0277	FAD linked oxidase domain protein
FORC23_1668	COG0247	lactate metabolic process
FORC23_1675	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FORC23_1678	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FORC23_1679	COG1643	Atp-dependent helicase
FORC23_1680	COG0281	malic enzyme
FORC23_1681	COG2949	membrane
FORC23_1682	COG0471	metal ion transport
FORC23_1683	COG0745	RESPONSE REGULATOR receiver
FORC23_1683	COG3706	GGDEF domain
FORC23_1687	COG0492	ferredoxin-NADP+ reductase activity
FORC23_1688	COG4988	ABC transporter
FORC23_1689	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FORC23_1690	COG3048	D-serine ammonia-lyase activity
FORC23_1691	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FORC23_1693	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC23_1693	COG4191	Histidine kinase
FORC23_1696	COG3070	regulator of competence-specific genes
FORC23_1698	COG2431	L-lysine efflux transmembrane transporter activity
FORC23_1700	COG0076	glutamate decarboxylase activity
FORC23_1701	COG1737	Transcriptional regulator
FORC23_1703	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FORC23_1704	COG3273	potassium ion transport
FORC23_1704	COG2985	domain, Protein
FORC23_1705	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC23_1708	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC23_1711	COG1136	(ABC) transporter
FORC23_1712	COG0534	Mate efflux family protein
FORC23_1713	COG0702	epimerase
FORC23_1714	COG3005	denitrification pathway
FORC23_1720	COG2814	Major facilitator Superfamily
FORC23_1721	COG1187	pseudouridine synthase activity
FORC23_1722	COG1061	Type III restriction enzyme res subunit
FORC23_1724	COG0745	RESPONSE REGULATOR receiver
FORC23_1725	COG2205	protein histidine kinase activity
FORC23_1726	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FORC23_1736	COG0493	'glutamate synthase
FORC23_1738	COG0398	Pfam SNARE associated Golgi protein
FORC23_1739	COG4134	Bacterial extracellular solute-binding protein
FORC23_1740	COG4135	transport system, permease component
FORC23_1741	COG4136	ATPase activity
FORC23_1742	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FORC23_1744	COG3604	Transcriptional regulator
FORC23_1745	COG1151	hydroxylamine reductase activity
FORC23_1746	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC23_1748	COG0564	pseudouridine synthase activity
FORC23_1750	COG0733	neurotransmitter:sodium symporter activity
FORC23_1752	COG0626	cystathionine gamma-synthase activity
FORC23_1753	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FORC23_1754	COG5380	lipid catabolic process
FORC23_1755	COG2818	Glycosylase
FORC23_1758	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC23_1759	COG1983	PspC domain protein
FORC23_1760	COG1842	Phage shock protein A
FORC23_1761	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FORC23_1763	COG4168	peptide transport system, permease
FORC23_1764	COG4171	peptide transport system, permease
FORC23_1766	COG4172	Belongs to the ABC transporter superfamily
FORC23_1768	COG1227	inorganic diphosphatase activity
FORC23_1771	COG0243	molybdopterin cofactor binding
FORC23_1772	COG3005	denitrification pathway
FORC23_1773	COG4459	periplasmic nitrate reductase
FORC23_1774	COG0390	transport system, permease component
FORC23_1775	COG2116	formate transmembrane transporter activity
FORC23_1780	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC23_1781	COG1435	thymidine kinase activity
FORC23_1782	COG0215	cysteine-tRNA ligase activity
FORC23_1783	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC23_1784	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FORC23_1785	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FORC23_1786	COG3012	SEC-C Motif Domain Protein
FORC23_1787	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FORC23_1787	COG0140	phosphoribosyl-ATP diphosphatase activity
FORC23_1788	COG0107	imidazoleglycerol-phosphate synthase activity
FORC23_1789	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FORC23_1790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FORC23_1791	COG0131	Imidazoleglycerol-phosphate dehydratase
FORC23_1791	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC23_1792	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FORC23_1793	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FORC23_1794	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FORC23_1796	COG1757	Na H antiporter
FORC23_1798	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC23_1800	COG0482	sulfurtransferase activity
FORC23_1801	COG2915	High frequency lysogenization protein hflD homolog
FORC23_1802	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FORC23_1806	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FORC23_1809	COG1028	Short-chain dehydrogenase reductase Sdr
FORC23_1811	COG0501	Belongs to the peptidase M48B family
FORC23_1813	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FORC23_1815	COG0156	8-amino-7-oxononanoate synthase activity
FORC23_1816	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FORC23_1817	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC23_1818	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FORC23_1821	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FORC23_1822	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FORC23_1823	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FORC23_1824	COG1674	ftsk spoiiie
FORC23_1826	COG0686	Belongs to the AlaDH PNT family
FORC23_1828	COG0583	DNA-binding transcription factor activity
FORC23_1831	COG3568	Endonuclease Exonuclease Phosphatase
FORC23_1836	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC23_1837	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC23_1838	COG0840	transmembrane signaling receptor activity
FORC23_1844	COG5002	protein histidine kinase activity
FORC23_1844	COG0784	Response regulator, receiver
FORC23_1846	COG0754	glutathionylspermidine amidase activity
FORC23_1848	COG3766	membrane
FORC23_1850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FORC23_1851	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FORC23_1852	COG2885	chlorophyll binding
FORC23_1853	COG0823	Involved in the tonB-independent uptake of proteins
FORC23_1856	COG0811	peptide transport
FORC23_1857	COG0824	Thioesterase
FORC23_1859	COG1294	oxidase, subunit
FORC23_1860	COG1271	oxidase subunit
FORC23_1861	COG2255	four-way junction helicase activity
FORC23_1862	COG0632	four-way junction helicase activity
FORC23_1863	COG0840	transmembrane signaling receptor activity
FORC23_1864	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FORC23_1865	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FORC23_1866	COG1801	Protein of unknown function DUF72
FORC23_1867	COG4106	trans-aconitate 2-methyltransferase activity
FORC23_1868	COG0500	methyltransferase
FORC23_1869	COG4067	protein conserved in archaea
FORC23_1869	COG0189	ligase activity
FORC23_1873	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC23_1874	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FORC23_1875	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FORC23_1876	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC23_1877	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FORC23_1878	COG0745	RESPONSE REGULATOR receiver
FORC23_1879	COG3381	protein complex oligomerization
FORC23_1880	COG1609	Transcriptional regulator
FORC23_1881	COG3070	regulator of competence-specific genes
FORC23_1885	COG0297	glycogen (starch) synthase activity
FORC23_1886	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC23_1887	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FORC23_1889	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FORC23_1891	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FORC23_1892	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FORC23_1893	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FORC23_1895	COG0542	response to heat
FORC23_1896	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FORC23_1897	COG1278	Cold shock
FORC23_1899	COG1187	pseudouridine synthase activity
FORC23_1900	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC23_1901	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC23_1902	COG1199	ATP-dependent helicase activity
FORC23_1903	COG0730	response to heat
FORC23_1904	COG3923	Primosomal replication protein n
FORC23_1906	COG0708	Exodeoxyribonuclease III
FORC23_1909	COG4215	(ABC) transporter
FORC23_1914	COG1882	Formate acetyltransferase
FORC23_1916	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC23_1918	COG3013	Belongs to the UPF0304 family
FORC23_1919	COG2766	serine protein kinase
FORC23_1920	COG2718	Belongs to the UPF0229 family
FORC23_1921	COG2719	SpoVR family
FORC23_1922	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FORC23_1924	COG1663	tetraacyldisaccharide 4'-kinase activity
FORC23_1925	COG1132	(ABC) transporter
FORC23_1926	COG2333	competence protein COMEC
FORC23_1926	COG0658	competence protein
FORC23_1928	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC23_1929	COG1136	(ABC) transporter
FORC23_1930	COG4591	ABC-type transport system involved in lipoprotein release permease component
FORC23_1932	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FORC23_1935	COG1252	NADH dehydrogenase
FORC23_1936	COG3150	esterase
FORC23_1941	COG0537	adenosine 5'-monophosphoramidase activity
FORC23_1946	COG0517	IMP dehydrogenase activity
FORC23_1946	COG0516	GMP reductase activity
FORC23_1947	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FORC23_1948	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC23_1949	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC23_1950	COG2199	diguanylate cyclase activity
FORC23_1953	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FORC23_1954	COG1946	Acyl-CoA thioesterase
FORC23_1956	COG1522	sequence-specific DNA binding
FORC23_1961	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC23_1962	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC23_1965	COG0477	Major facilitator Superfamily
FORC23_1966	COG2855	membrane
FORC23_1969	COG1441	menaquinone biosynthetic process
FORC23_1970	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FORC23_1971	COG0596	Alpha beta hydrolase
FORC23_1972	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FORC23_1973	COG1169	isochorismate synthase
FORC23_1974	COG0436	Aminotransferase
FORC23_1975	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FORC23_1976	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FORC23_1979	COG1555	photosystem II stabilization
FORC23_1980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC23_1981	COG0776	regulation of translation
FORC23_1982	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FORC23_1983	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FORC23_1985	COG0544	peptidyl-prolyl cis-trans isomerase activity
FORC23_1988	COG2204	response regulator
FORC23_1989	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FORC23_1990	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC23_1991	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FORC23_1992	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FORC23_1995	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC23_1996	COG0569	domain protein
FORC23_1997	COG0513	Belongs to the DEAD box helicase family
FORC23_1998	COG1253	flavin adenine dinucleotide binding
FORC23_2005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC23_2006	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FORC23_2009	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC23_2010	COG1216	Glycosyl transferase, family 2
FORC23_2011	COG2986	histidine ammonia-lyase
FORC23_2016	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FORC23_2017	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FORC23_2018	COG1028	Short-chain dehydrogenase reductase Sdr
FORC23_2021	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FORC23_2022	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC23_2023	COG0583	DNA-binding transcription factor activity
FORC23_2024	COG2951	lytic endotransglycosylase activity
FORC23_2025	COG3100	YcgL domain-containing protein
FORC23_2026	COG0850	regulation of cytokinetic process
FORC23_2027	COG2894	cell division
FORC23_2028	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FORC23_2029	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FORC23_2030	COG0318	PFAM AMP-dependent synthetase and ligase
FORC23_2031	COG2267	carboxylic ester hydrolase activity
FORC23_2034	COG1214	PFAM Peptidase M22, glycoprotease
FORC23_2035	COG1199	ATP-dependent helicase activity
FORC23_2036	COG0788	formyltetrahydrofolate deformylase activity
FORC23_2039	COG3102	Protein conserved in bacteria
FORC23_2040	COG0018	arginyl-trna synthetase
FORC23_2044	COG1918	ferrous iron import across plasma membrane
FORC23_2045	COG4977	sequence-specific DNA binding
FORC23_2046	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FORC23_2047	COG1121	(ABC) transporter
FORC23_2048	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC23_2050	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC23_2051	COG0508	dehydrogenase complex catalyzes the overall conversion of
FORC23_2052	COG0567	Dehydrogenase, E1 component
FORC23_2053	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FORC23_2054	COG1053	succinate dehydrogenase
FORC23_2055	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FORC23_2056	COG2009	succinate dehydrogenase
FORC23_2058	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FORC23_2060	COG0033	Phosphoglucomutase
FORC23_2061	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FORC23_2062	COG0596	Alpha beta hydrolase
FORC23_2064	COG0716	FMN binding
FORC23_2066	COG0735	belongs to the Fur family
FORC23_2067	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC23_2068	COG2190	(PTS) system
FORC23_2068	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC23_2068	COG1263	PTS System
FORC23_2069	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FORC23_2070	COG1846	Transcriptional regulator
FORC23_2070	COG1940	carbohydrate kinase activity
FORC23_2071	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FORC23_2071	COG4651	solute:proton antiporter activity
FORC23_2072	COG0367	asparagine synthase
FORC23_2073	COG0250	Participates in transcription elongation, termination and antitermination
FORC23_2074	COG3104	oligopeptide transport
FORC23_2075	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FORC23_2076	COG0563	adenylate kinase activity
FORC23_2077	COG0326	Molecular chaperone. Has ATPase activity
FORC23_2078	COG3710	Transcriptional regulator
FORC23_2082	COG0622	Phosphoesterase
FORC23_2088	COG1090	epimerase
FORC23_2089	COG0300	oxidoreductase activity
FORC23_2090	COG3118	belongs to the thioredoxin family
FORC23_2091	COG3118	belongs to the thioredoxin family
FORC23_2091	COG0457	Tetratricopeptide repeat
FORC23_2092	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FORC23_2093	COG1215	transferase activity, transferring glycosyl groups
FORC23_2094	COG1215	transferase activity, transferring glycosyl groups
FORC23_2099	COG2194	sulfuric ester hydrolase activity
FORC23_2100	COG0330	HflC and HflK could
FORC23_2103	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FORC23_2104	COG3115	cell septum assembly
FORC23_2105	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FORC23_2106	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FORC23_2107	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC23_2108	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC23_2109	COG2190	(PTS) system
FORC23_2110	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC23_2111	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC23_2112	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC23_2113	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC23_2115	COG1705	Flagellar rod assembly protein muramidase FlgJ
FORC23_2115	COG3951	Flagellar rod assembly protein muramidase FlgJ
FORC23_2116	COG1706	bacterial-type flagellum-dependent cell motility
FORC23_2117	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FORC23_2118	COG4786	Flagellar basal body rod
FORC23_2119	COG4787	bacterial-type flagellum-dependent cell motility
FORC23_2120	COG1749	Flagellar hook protein flgE
FORC23_2121	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FORC23_2122	COG1558	bacterial-type flagellum-dependent cell motility
FORC23_2123	COG1815	bacterial-type flagellum-dependent cell motility
FORC23_2124	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FORC23_2125	COG0784	Response regulator, receiver
FORC23_2125	COG0835	chemotaxis
FORC23_2134	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FORC23_2135	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC23_2137	COG2608	mercury ion transmembrane transporter activity
FORC23_2137	COG2217	Heavy metal translocating P-type atpase
FORC23_2142	COG2840	Smr protein MutS2
FORC23_2143	COG1187	pseudouridine synthase activity
FORC23_2145	COG0737	Belongs to the 5'-nucleotidase family
FORC23_2146	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FORC23_2147	COG2912	Transglutaminase-like superfamily
FORC23_2148	COG3094	Invasion gene expression up-regulator, SirB
FORC23_2149	COG2890	protein-(glutamine-N5) methyltransferase activity
FORC23_2150	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FORC23_2151	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FORC23_2152	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FORC23_2153	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FORC23_2154	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FORC23_2155	COG0193	aminoacyl-tRNA hydrolase activity
FORC23_2156	COG0012	GTP binding
FORC23_2157	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FORC23_2158	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FORC23_2159	COG1702	phosphate starvation-inducible protein PhoH
FORC23_2160	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FORC23_2161	COG4535	Mg2 and Co2 transporter CorC
FORC23_2162	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FORC23_2163	COG2888	peptidyl-tyrosine sulfation
FORC23_2164	COG0495	leucyl-tRNA aminoacylation
FORC23_2165	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FORC23_2166	COG1466	dna polymerase III delta subunit
FORC23_2167	COG0799	negative regulation of ribosome biogenesis
FORC23_2168	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FORC23_2169	COG0768	penicillin binding
FORC23_2170	COG0772	Belongs to the SEDS family
FORC23_2171	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FORC23_2172	COG1686	Belongs to the peptidase S11 family
FORC23_2173	COG2921	Belongs to the UPF0250 family
FORC23_2174	COG0321	lipoyl(octanoyl) transferase activity
FORC23_2175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FORC23_2176	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC23_2179	COG0366	Alpha amylase catalytic
FORC23_2180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC23_2180	COG1263	PTS System
FORC23_2182	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FORC23_2183	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FORC23_2184	COG2011	ABC-type metal ion transport system permease component
FORC23_2185	COG1464	Belongs to the NlpA lipoprotein family
FORC23_2186	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FORC23_2188	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC23_2188	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FORC23_2190	COG0745	RESPONSE REGULATOR receiver
FORC23_2190	COG3706	GGDEF domain
FORC23_2191	COG1611	Belongs to the LOG family
FORC23_2192	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC23_2194	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FORC23_2195	COG2363	Small membrane protein
FORC23_2197	COG0583	DNA-binding transcription factor activity
FORC23_2198	COG0301	tRNA thio-modification
FORC23_2198	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC23_2199	COG2885	chlorophyll binding
FORC23_2200	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC23_2201	COG1722	exodeoxyribonuclease VII activity
FORC23_2202	COG0142	geranyltranstransferase activity
FORC23_2203	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FORC23_2204	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FORC23_2205	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FORC23_2206	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FORC23_2210	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC23_2210	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC23_2211	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FORC23_2212	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FORC23_2213	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FORC23_2216	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FORC23_2217	COG2252	PERMEase
FORC23_2218	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC23_2223	COG0047	phosphoribosylformylglycinamidine synthase activity
FORC23_2223	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FORC23_2224	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FORC23_2225	COG0590	tRNA wobble adenosine to inosine editing
FORC23_2226	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FORC23_2233	COG0484	heat shock protein binding
FORC23_2234	COG0443	Heat shock 70 kDa protein
FORC23_2236	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FORC23_2237	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FORC23_2239	COG0497	DNA recombination
FORC23_2240	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC23_2241	COG2914	Belongs to the UPF0125 (RnfH) family
FORC23_2242	COG2867	negative regulation of translational initiation
FORC23_2243	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FORC23_2245	COG0583	DNA-binding transcription factor activity
FORC23_2246	COG3153	acetyltransferase
FORC23_2246	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FORC23_2250	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FORC23_2251	COG2873	o-acetylhomoserine
FORC23_2257	COG1115	amino acid carrier protein
FORC23_2259	COG1584	GPR1 FUN34 yaaH family protein
FORC23_2261	COG1757	Na H antiporter
FORC23_2274	COG0582	viral genome integration into host DNA
FORC23_2275	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FORC23_2275	COG0519	Catalyzes the synthesis of GMP from XMP
FORC23_2276	COG0516	GMP reductase activity
FORC23_2276	COG0517	IMP dehydrogenase activity
FORC23_2277	COG1570	exodeoxyribonuclease VII activity
FORC23_2280	COG1160	GTP binding
FORC23_2281	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC23_2282	COG2976	Protein conserved in bacteria
FORC23_2283	COG0124	histidyl-tRNA synthetase
FORC23_2284	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FORC23_2286	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FORC23_2287	COG0105	UTP biosynthetic process
FORC23_2288	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FORC23_2289	COG2975	iron-sulfur cluster assembly
FORC23_2290	COG0633	Ferredoxin
FORC23_2291	COG0443	Heat shock 70 kDa protein
FORC23_2292	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC23_2294	COG0822	iron-sulfur transferase activity
FORC23_2295	COG1104	cysteine desulfurase activity
FORC23_2298	COG0483	inositol monophosphate 1-phosphatase activity
FORC23_2299	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC23_2300	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC23_2301	COG1862	Preprotein translocase
FORC23_2302	COG0343	queuine tRNA-ribosyltransferase activity
FORC23_2303	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FORC23_2305	COG0517	IMP dehydrogenase activity
FORC23_2307	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FORC23_2308	COG0583	DNA-binding transcription factor activity
FORC23_2309	COG0450	alkyl hydroperoxide reductase
FORC23_2310	COG3142	Participates in the control of copper homeostasis
FORC23_2312	COG0704	Plays a role in the regulation of phosphate uptake
FORC23_2313	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC23_2314	COG0581	inorganic phosphate transmembrane transporter activity
FORC23_2316	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FORC23_2317	COG0248	Ppx GppA phosphatase
FORC23_2319	COG5002	protein histidine kinase activity
FORC23_2320	COG0745	RESPONSE REGULATOR receiver
FORC23_2321	COG2974	May be involved in recombination
FORC23_2323	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC23_2327	COG0542	response to heat
FORC23_2329	COG0564	pseudouridine synthase activity
FORC23_2330	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC23_2331	COG0741	lytic transglycosylase activity
FORC23_2332	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FORC23_2333	COG1605	Chorismate mutase
FORC23_2333	COG0077	Prephenate dehydratase
FORC23_2334	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FORC23_2335	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FORC23_2337	COG0488	(ABC) transporter
FORC23_2339	COG0739	heme binding
FORC23_2340	COG1605	Chorismate mutase
FORC23_2340	COG0287	Prephenate dehydrogenase
FORC23_2341	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC23_2342	COG1472	Belongs to the glycosyl hydrolase 3 family
FORC23_2343	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FORC23_2344	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC23_2347	COG1966	Carbon starvation protein
FORC23_2348	COG3275	phosphorelay sensor kinase activity
FORC23_2349	COG3279	Response regulator of the LytR AlgR family
FORC23_2350	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FORC23_2351	COG1047	Peptidyl-prolyl cis-trans
FORC23_2352	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FORC23_2353	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC23_2354	COG0196	riboflavin kinase activity
FORC23_2355	COG0728	peptidoglycan biosynthetic process
FORC23_2356	COG0268	Binds directly to 16S ribosomal RNA
FORC23_2357	COG0640	Transcriptional regulator
FORC23_2358	COG0583	DNA-binding transcription factor activity
FORC23_2360	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FORC23_2361	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FORC23_2362	COG0730	response to heat
FORC23_2364	COG0494	nUDIX hydrolase
FORC23_2365	COG3066	DNA modification
FORC23_2367	COG0667	Aldo Keto reductase
FORC23_2369	COG2204	response regulator
FORC23_2370	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FORC23_2371	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FORC23_2372	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC23_2374	COG0716	FMN binding
FORC23_2376	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FORC23_2377	COG0513	Belongs to the DEAD box helicase family
FORC23_2378	COG3022	response to hydroperoxide
FORC23_2379	COG1115	amino acid carrier protein
FORC23_2382	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FORC23_2383	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FORC23_2384	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FORC23_2385	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FORC23_2386	COG0083	homoserine kinase activity
FORC23_2389	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC23_2391	COG0745	RESPONSE REGULATOR receiver
FORC23_2393	COG0784	Response regulator, receiver
FORC23_2393	COG2198	Histidine kinase
FORC23_2393	COG5002	protein histidine kinase activity
FORC23_2394	COG4251	negative regulation of phosphorylation
FORC23_2394	COG2203	Gaf domain
FORC23_2394	COG3706	GGDEF domain
FORC23_2394	COG5001	Diguanylate cyclase
FORC23_2395	COG1242	4 iron, 4 sulfur cluster binding
FORC23_2396	COG0069	glutamate synthase activity
FORC23_2396	COG0067	glutamate synthase
FORC23_2396	COG0070	glutamate synthase
FORC23_2398	COG0069	glutamate synthase activity
FORC23_2398	COG0067	glutamate synthase
FORC23_2398	COG0070	glutamate synthase
FORC23_2399	COG0493	'glutamate synthase
FORC23_2401	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC23_2403	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC23_2404	COG2860	membrane
FORC23_2405	COG0583	DNA-binding transcription factor activity
FORC23_2406	COG0730	response to heat
FORC23_2409	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FORC23_2410	COG0505	Belongs to the CarA family
FORC23_2411	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FORC23_2412	COG0494	nUDIX hydrolase
FORC23_2413	COG0653	protein targeting
FORC23_2415	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FORC23_2416	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FORC23_2417	COG0849	cell division
FORC23_2418	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FORC23_2419	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC23_2420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FORC23_2421	COG0772	Belongs to the SEDS family
FORC23_2422	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FORC23_2423	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC23_2424	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FORC23_2425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FORC23_2426	COG0768	penicillin binding
FORC23_2427	COG3116	cell division
FORC23_2428	COG0275	rRNA processing
FORC23_2429	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FORC23_2431	COG0792	nuclease activity
FORC23_2432	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FORC23_2433	COG2823	Periplasmic or secreted lipoprotein
FORC23_2434	COG2969	positive regulation of protein catabolic process
FORC23_2435	COG0625	glutathione transferase activity
FORC23_2436	COG2857	Cytochrome c1
FORC23_2437	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FORC23_2438	COG0723	plastoquinol--plastocyanin reductase activity
FORC23_2439	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FORC23_2440	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FORC23_2441	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FORC23_2442	COG3105	Protein conserved in bacteria
FORC23_2444	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FORC23_2445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FORC23_2446	COG0187	DNA topoisomerase II activity
FORC23_2447	COG3150	esterase
FORC23_2449	COG3151	Protein conserved in bacteria
FORC23_2450	COG0494	nUDIX hydrolase
FORC23_2451	COG1538	Outer membrane efflux protein
FORC23_2452	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FORC23_2452	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FORC23_2453	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FORC23_2456	COG3025	triphosphatase activity
FORC23_2457	COG1392	Phosphate transport regulator
FORC23_2458	COG0306	phosphate transporter
FORC23_2459	COG4991	sh3 domain protein
FORC23_2461	COG3267	Type II secretory pathway component ExeA
FORC23_2461	COG3409	Peptidoglycan-binding domain 1 protein
FORC23_2462	COG0617	tRNA 3'-terminal CCA addition
FORC23_2463	COG1968	undecaprenyl-diphosphatase activity
FORC23_2464	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FORC23_2465	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FORC23_2466	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FORC23_2467	COG0596	Alpha beta hydrolase
FORC23_2468	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FORC23_2469	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FORC23_2470	COG1610	YqeY-like protein
FORC23_2471	COG0358	DNA primase activity
FORC23_2472	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FORC23_2473	COG1464	Belongs to the NlpA lipoprotein family
FORC23_2479	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC23_2479	COG2213	PTS system mannitol-specific
FORC23_2480	COG0246	Mannitol dehydrogenase
FORC23_2481	COG3722	fumarate hydratase activity
FORC23_2484	COG1461	Dihydroxyacetone kinase
FORC23_2485	COG2376	Dihydroxyacetone kinase
FORC23_2487	COG5002	protein histidine kinase activity
FORC23_2490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FORC23_2491	COG1349	DNA-binding transcription factor activity
FORC23_2492	COG0469	pyruvate kinase activity
FORC23_2494	COG3706	GGDEF domain
FORC23_2495	COG0440	acetolactate synthase activity
FORC23_2496	COG0028	Belongs to the TPP enzyme family
FORC23_2497	COG1022	Amp-dependent synthetase and ligase
FORC23_2498	COG0583	DNA-binding transcription factor activity
FORC23_2502	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC23_2503	COG0473	3-isopropylmalate dehydrogenase activity
FORC23_2504	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FORC23_2505	COG0066	3-isopropylmalate dehydratase activity
FORC23_2507	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FORC23_2508	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FORC23_2509	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC23_2510	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FORC23_2511	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FORC23_2512	COG2967	ApaG domain
FORC23_2513	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FORC23_2516	COG2966	Psort location CytoplasmicMembrane, score
FORC23_2517	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FORC23_2519	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FORC23_2520	COG0142	geranyltranstransferase activity
FORC23_2522	COG0039	L-malate dehydrogenase activity
FORC23_2527	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FORC23_2528	COG1178	ABC-type Fe3 transport system permease component
FORC23_2529	COG4143	(ABC) transporter
FORC23_2530	COG0163	prenyltransferase activity
FORC23_2531	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FORC23_2532	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FORC23_2533	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FORC23_2535	COG2105	PFAM AIG2 family protein
FORC23_2537	COG0729	surface antigen
FORC23_2538	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC23_2540	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC23_2543	COG4181	ATPase activity
FORC23_2547	COG0529	Catalyzes the synthesis of activated sulfate
FORC23_2548	COG3273	potassium ion transport
FORC23_2548	COG0471	metal ion transport
FORC23_2549	COG2895	sulfate adenylyltransferase (ATP) activity
FORC23_2550	COG0175	sulfate reduction
FORC23_2551	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC23_2551	COG1648	precorrin-2 dehydrogenase activity
FORC23_2552	COG0737	Belongs to the 5'-nucleotidase family
FORC23_2554	COG0513	Belongs to the DEAD box helicase family
FORC23_2555	COG2153	protein acetylation
FORC23_2557	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC23_2559	COG0203	ribosomal protein L17
FORC23_2560	COG0202	RNA polymerase activity
FORC23_2562	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FORC23_2563	COG0201	protein transport
FORC23_2564	COG0200	Binds to the 23S rRNA
FORC23_2565	COG1841	ribosomal large subunit assembly
FORC23_2568	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FORC23_2569	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FORC23_2570	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FORC23_2571	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FORC23_2572	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FORC23_2573	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FORC23_2574	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FORC23_2575	COG0255	Belongs to the universal ribosomal protein uL29 family
FORC23_2577	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FORC23_2578	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FORC23_2579	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FORC23_2580	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FORC23_2582	COG0088	Forms part of the polypeptide exit tunnel
FORC23_2583	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FORC23_2585	COG0254	rRNA binding
FORC23_2586	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FORC23_2587	COG1609	Transcriptional regulator
FORC23_2589	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FORC23_2590	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FORC23_2591	COG1575	Belongs to the MenA family. Type 1 subfamily
FORC23_2592	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FORC23_2593	COG3074	FtsZ-dependent cytokinesis
FORC23_2594	COG1494	fructose-1,6-bisphosphatase
FORC23_2599	COG0149	triose-phosphate isomerase activity
FORC23_2603	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC23_2604	COG2030	dehydratase
FORC23_2606	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FORC23_2610	COG1215	transferase activity, transferring glycosyl groups
FORC23_2611	COG0110	maltose O-acetyltransferase activity
FORC23_2613	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FORC23_2614	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FORC23_2615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FORC23_2619	COG1086	Polysaccharide biosynthesis protein
FORC23_2624	COG0110	maltose O-acetyltransferase activity
FORC23_2633	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FORC23_2635	COG1560	Kdo2-lipid A biosynthetic process
FORC23_2636	COG0859	PFAM glycosyl transferase family 9
FORC23_2637	COG1519	Transferase
FORC23_2639	COG1083	cytidylyl-transferase
FORC23_2640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FORC23_2642	COG2089	acid synthase
FORC23_2643	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FORC23_2644	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC23_2647	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FORC23_2651	COG3642	lipopolysaccharide core region biosynthetic process
FORC23_2652	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC23_2653	COG0859	PFAM glycosyl transferase family 9
FORC23_2654	COG0463	Glycosyl transferase, family 2
FORC23_2659	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FORC23_2662	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FORC23_2663	COG2003	Belongs to the UPF0758 family
FORC23_2665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FORC23_2666	COG1309	transcriptional regulator
FORC23_2667	COG1560	Kdo2-lipid A biosynthetic process
FORC23_2668	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FORC23_2669	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FORC23_2670	COG1561	YicC-like family, N-terminal region
FORC23_2672	COG0747	negative chemotaxis
FORC23_2673	COG4239	(ABC) transporter, permease
FORC23_2674	COG4174	ABC transporter (Permease)
FORC23_2678	COG0811	peptide transport
FORC23_2679	COG0848	biopolymer transport protein
FORC23_2682	COG0194	GDP metabolic process
FORC23_2683	COG1758	RNA polymerase activity
FORC23_2684	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FORC23_2685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FORC23_2686	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FORC23_2687	COG2233	PERMEase
FORC23_2688	COG2205	protein histidine kinase activity
FORC23_2689	COG0745	RESPONSE REGULATOR receiver
FORC23_2691	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC23_2693	COG2183	response to ionizing radiation
FORC23_2695	COG0596	Alpha beta hydrolase
FORC23_2696	COG1040	competence protein
FORC23_2697	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FORC23_2697	COG0316	Belongs to the HesB IscA family
FORC23_2698	COG0494	nUDIX hydrolase
FORC23_2699	COG1218	3'(2'),5'-bisphosphate nucleotidase
FORC23_2701	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC23_2702	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FORC23_2703	COG3156	type II secretion system protein K
FORC23_2704	COG4795	General secretion pathway protein
FORC23_2705	COG2165	general secretion pathway protein
FORC23_2706	COG2165	general secretion pathway protein
FORC23_2707	COG2165	general secretion pathway protein
FORC23_2708	COG1459	type II secretion system
FORC23_2709	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FORC23_2711	COG3031	protein transport across the cell outer membrane
FORC23_2712	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FORC23_2713	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FORC23_2714	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FORC23_2716	COG0456	acetyltransferase
FORC23_2717	COG1490	D-aminoacyl-tRNA deacylase activity
FORC23_2718	COG1295	ribonuclease BN
FORC23_2722	COG0174	glutamine synthetase
FORC23_2724	COG3852	Histidine kinase
FORC23_2725	COG2204	response regulator
FORC23_2727	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC23_2728	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FORC23_2733	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FORC23_2734	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC23_2734	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FORC23_2737	COG0084	hydrolase, TatD family'
FORC23_2738	COG0805	protein transport
FORC23_2740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FORC23_2741	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FORC23_2742	COG3165	ubiquinone biosynthetic process from chorismate
FORC23_2743	COG2226	methyltransferase
FORC23_2744	COG1322	Protein conserved in bacteria
FORC23_2747	COG0628	permease
FORC23_2757	COG2823	Periplasmic or secreted lipoprotein
FORC23_2759	COG2081	HI0933 family
FORC23_2761	COG1528	Iron-storage protein
FORC23_2762	COG0589	response to stress
FORC23_2763	COG0697	spore germination
FORC23_2765	COG0742	ribosomal rna small subunit methyltransferase
FORC23_2766	COG5002	protein histidine kinase activity
FORC23_2766	COG5001	Diguanylate cyclase
FORC23_2767	COG1522	sequence-specific DNA binding
FORC23_2768	COG0339	signal peptide processing
FORC23_2769	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FORC23_2770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FORC23_2771	COG0583	DNA-binding transcription factor activity
FORC23_2772	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FORC23_2773	COG0800	Aldolase
FORC23_2774	COG2610	gluconate transmembrane transporter activity
FORC23_2775	COG3265	gluconokinase activity
FORC23_2776	COG0129	dihydroxy-acid dehydratase activity
FORC23_2777	COG2076	Multidrug Resistance protein
FORC23_2779	COG0583	DNA-binding transcription factor activity
FORC23_2780	COG1609	Transcriptional regulator
FORC23_2787	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FORC23_2789	COG0747	negative chemotaxis
FORC23_2790	COG4172	Belongs to the ABC transporter superfamily
FORC23_2796	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC23_2797	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC23_2798	COG2960	long-chain fatty acid transporting porin activity
FORC23_2799	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FORC23_2800	COG0583	DNA-binding transcription factor activity
FORC23_2803	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC23_2804	COG1739	Uncharacterized protein family UPF0029
FORC23_2805	COG1024	Enoyl-CoA hydratase
FORC23_2805	COG1250	3-hydroxyacyl-CoA dehydrogenase
FORC23_2806	COG0183	Belongs to the thiolase family
FORC23_2807	COG0604	alcohol dehydrogenase
FORC23_2810	COG0425	Belongs to the sulfur carrier protein TusA family
FORC23_2812	COG2119	membrane
FORC23_2813	COG0752	glycyl-tRNA synthetase alpha subunit
FORC23_2814	COG0751	glycine-tRNA ligase activity
FORC23_2815	COG0366	Alpha amylase catalytic
FORC23_2816	COG3977	Valine--pyruvate aminotransferase
FORC23_2817	COG0071	Belongs to the small heat shock protein (HSP20) family
FORC23_2819	COG0187	DNA topoisomerase II activity
FORC23_2820	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC23_2821	COG0592	DNA-directed DNA polymerase activity
FORC23_2824	COG4608	Belongs to the ABC transporter superfamily
FORC23_2825	COG0444	Belongs to the ABC transporter superfamily
FORC23_2827	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC23_2827	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FORC23_2831	COG0217	transcriptional regulatory protein
FORC23_2832	COG0772	Belongs to the SEDS family
FORC23_2838	COG3275	phosphorelay sensor kinase activity
FORC23_2839	COG3279	Response regulator of the LytR AlgR family
FORC23_2841	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FORC23_2846	COG0786	glutamate:sodium symporter activity
FORC23_2848	COG1131	(ABC) transporter
FORC23_2849	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC23_2850	COG0786	glutamate:sodium symporter activity
FORC23_2852	COG0363	glucosamine-6-phosphate deaminase activity
FORC23_2856	COG1741	Belongs to the pirin family
FORC23_2857	COG2259	Doxx family
FORC23_2859	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FORC23_2860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FORC23_2869	COG3123	guanosine phosphorylase activity
FORC23_2871	COG5001	Diguanylate cyclase
FORC23_2872	COG0534	Mate efflux family protein
FORC23_2873	COG0564	pseudouridine synthase activity
FORC23_2876	COG0583	DNA-binding transcription factor activity
FORC23_2877	COG0561	phosphatase activity
FORC23_2879	COG2199	diguanylate cyclase activity
FORC23_2882	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FORC23_2883	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FORC23_2884	COG0583	DNA-binding transcription factor activity
FORC23_2885	COG2176	DNA-directed DNA polymerase activity
FORC23_2887	COG1414	Transcriptional regulator
FORC23_2888	COG1028	Short-chain dehydrogenase reductase Sdr
FORC23_2890	COG1917	Cupin 2, conserved barrel domain protein
FORC23_2893	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC23_2894	COG0800	Aldolase
FORC23_2898	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC23_2899	COG0823	Involved in the tonB-independent uptake of proteins
FORC23_2900	COG2375	cellular response to nickel ion
FORC23_2905	COG1357	PFAM Pentapeptide repeats (8 copies)
FORC23_2906	COG3047	cAMP biosynthetic process
FORC23_2912	COG3408	Glycogen debranching enzyme
FORC23_2912	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FORC23_2913	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FORC23_2917	COG0583	DNA-binding transcription factor activity
FORC23_2920	COG0546	phosphoglycolate phosphatase activity
FORC23_2925	COG3835	regulator
FORC23_2926	COG2610	gluconate transmembrane transporter activity
FORC23_2927	COG1929	Belongs to the glycerate kinase type-1 family
FORC23_2928	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC23_2932	COG0456	acetyltransferase
FORC23_2935	COG1028	Short-chain dehydrogenase reductase Sdr
FORC23_2937	COG3005	denitrification pathway
FORC23_2938	COG0243	molybdopterin cofactor binding
FORC23_2940	COG0352	thiamine-phosphate diphosphorylase activity
FORC23_2941	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FORC23_2942	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FORC23_2943	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC23_2944	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC23_2945	COG1116	anion transmembrane transporter activity
FORC23_2946	COG0351	phosphomethylpyrimidine kinase
FORC23_2947	COG0312	modulator of DNA gyrase
FORC23_2948	COG0312	modulator of DNA gyrase
FORC23_2949	COG1901	pseudouridine methyltransferase
FORC23_2952	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FORC23_2954	COG0584	glycerophosphoryl diester phosphodiesterase
FORC23_2956	COG0745	RESPONSE REGULATOR receiver
FORC23_2960	COG0811	peptide transport
FORC23_2961	COG0811	peptide transport
FORC23_2962	COG0848	biopolymer transport protein
FORC23_2970	COG0803	Belongs to the bacterial solute-binding protein 9 family
FORC23_2971	COG1121	(ABC) transporter
FORC23_2972	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FORC23_2975	COG1770	oligopeptidase
FORC23_2976	COG2814	Major facilitator Superfamily
FORC23_2977	COG0010	Belongs to the arginase family
FORC23_2978	COG1166	arginine decarboxylase activity
FORC23_2980	COG0189	ligase activity
FORC23_2980	COG4067	protein conserved in archaea
FORC23_2981	COG0189	ligase activity
FORC23_2982	COG0583	DNA-binding transcription factor activity
FORC23_2991	COG5001	Diguanylate cyclase
FORC23_2995	COG0579	oxidoreductase
FORC23_2997	COG3033	Beta-eliminating lyase
FORC23_2999	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FORC23_3002	COG3706	GGDEF domain
FORC23_3003	COG0840	transmembrane signaling receptor activity
FORC23_3006	COG3706	GGDEF domain
FORC23_3007	COG0415	Belongs to the DNA photolyase family
FORC23_3008	COG3046	protein related to deoxyribodipyrimidine photolyase
FORC23_3010	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC23_3010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FORC23_3011	COG1765	OsmC-like protein
FORC23_3012	COG0110	maltose O-acetyltransferase activity
FORC23_3020	COG1011	Hydrolase
FORC23_3023	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FORC23_3025	COG2067	long-chain fatty acid transport protein
FORC23_3026	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC23_3027	COG0577	efflux transmembrane transporter activity
FORC23_3027	COG1136	(ABC) transporter
FORC23_3029	COG3240	lipase activity
FORC23_3035	COG1609	Transcriptional regulator
FORC23_3036	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC23_3039	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC23_3041	COG3842	ATPase activity
FORC23_3046	COG2990	Protein conserved in bacteria
FORC23_3048	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FORC23_3049	COG2866	Carboxypeptidase
FORC23_3051	COG0583	DNA-binding transcription factor activity
FORC23_3056	COG1760	l-serine dehydratase
FORC23_3060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FORC23_3061	COG0741	lytic transglycosylase activity
FORC23_3065	COG1815	bacterial-type flagellum-dependent cell motility
FORC23_3066	COG1558	bacterial-type flagellum-dependent cell motility
FORC23_3067	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FORC23_3068	COG1749	Flagellar hook protein flgE
FORC23_3069	COG4787	bacterial-type flagellum-dependent cell motility
FORC23_3070	COG4786	Flagellar basal body rod
FORC23_3071	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FORC23_3072	COG1706	bacterial-type flagellum-dependent cell motility
FORC23_3074	COG4786	Flagellar basal body rod
FORC23_3074	COG1256	bacterial-type flagellum assembly
FORC23_3075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC23_3079	COG1304	FMN binding
FORC23_3084	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FORC23_3085	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FORC23_3086	COG0459	protein refolding
FORC23_3089	COG1280	lysine exporter protein (LysE YggA)
FORC23_3093	COG1309	transcriptional regulator
FORC23_3095	COG0737	Belongs to the 5'-nucleotidase family
FORC23_3096	COG2070	2-Nitropropane dioxygenase
FORC23_3097	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC23_3100	COG0346	lactoylglutathione lyase activity
FORC23_3101	COG1349	DNA-binding transcription factor activity
FORC23_3103	COG0753	catalase activity
FORC23_3105	COG1335	isochorismatase
FORC23_3107	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FORC23_3112	COG0583	DNA-binding transcription factor activity
FORC23_3115	COG3713	MltA-interacting MipA family protein
FORC23_3116	COG3015	lipoprotein NlpE involved in copper resistance
FORC23_3117	COG1342	Belongs to the UPF0251 family
FORC23_3122	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FORC23_3123	COG4948	Mandelate Racemase Muconate Lactonizing
FORC23_3125	COG0583	DNA-binding transcription factor activity
FORC23_3131	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC23_3136	COG3842	ATPase activity
FORC23_3142	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FORC23_3146	COG3706	GGDEF domain
FORC23_3150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC23_3153	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FORC23_3154	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FORC23_3157	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FORC23_3157	COG0574	Belongs to the PEP-utilizing enzyme family
FORC23_3158	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FORC23_3159	COG0252	asparaginase activity
FORC23_3161	COG0583	DNA-binding transcription factor activity
FORC23_3165	COG3122	Protein conserved in bacteria
FORC23_3167	COG1028	Short-chain dehydrogenase reductase Sdr
FORC23_3169	COG1063	alcohol dehydrogenase
FORC23_3170	COG1902	pentaerythritol trinitrate reductase activity
FORC23_3173	COG0583	DNA-binding transcription factor activity
FORC23_3175	COG0513	Belongs to the DEAD box helicase family
FORC23_3180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC23_3181	COG2207	Transcriptional regulator
FORC23_3181	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FORC23_3185	COG3746	phosphate-selective porin O and P
FORC23_3188	COG1028	Short-chain dehydrogenase reductase Sdr
FORC23_3192	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FORC23_3193	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FORC23_3196	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FORC23_3198	COG0625	glutathione transferase activity
FORC23_3200	COG1686	Belongs to the peptidase S11 family
FORC23_3203	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FORC23_3205	COG1741	Belongs to the pirin family
FORC23_3206	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC23_3208	COG1846	Transcriptional regulator
FORC23_3211	COG2814	Major facilitator Superfamily
FORC23_3212	COG0673	inositol 2-dehydrogenase activity
FORC23_3213	COG2194	sulfuric ester hydrolase activity
FORC23_3214	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FORC23_3216	COG2205	protein histidine kinase activity
FORC23_3217	COG0745	RESPONSE REGULATOR receiver
FORC23_3218	COG4221	oxidoreductase activity
FORC23_3221	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC23_3225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FORC23_3229	COG1418	mRNA catabolic process
FORC23_3231	COG0402	S-adenosylhomocysteine deaminase activity
FORC23_3232	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FORC23_3233	COG2239	Acts as a magnesium transporter
FORC23_3234	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FORC23_3237	COG0531	amino acid
FORC23_3238	COG1522	sequence-specific DNA binding
FORC23_3239	COG0583	DNA-binding transcription factor activity
FORC23_3243	COG0784	Response regulator, receiver
FORC23_3243	COG2205	protein histidine kinase activity
FORC23_3243	COG5002	protein histidine kinase activity
FORC23_3244	COG0673	inositol 2-dehydrogenase activity
FORC23_3245	COG0534	Mate efflux family protein
FORC23_3246	COG2926	Belongs to the UPF0265 family
FORC23_3248	COG3132	Protein of unknown function, DUF480
FORC23_3249	COG2827	Endonuclease containing a URI domain
FORC23_3250	COG1879	ABC-type sugar transport system periplasmic component
FORC23_3251	COG0784	Response regulator, receiver
FORC23_3251	COG2205	protein histidine kinase activity
FORC23_3253	COG1566	PFAM secretion protein HlyD family protein
FORC23_3257	COG1522	sequence-specific DNA binding
FORC23_3262	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC23_3263	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FORC23_3265	COG1280	lysine exporter protein (LysE YggA)
FORC23_3267	COG0183	Belongs to the thiolase family
FORC23_3270	COG3005	denitrification pathway
FORC23_3272	COG0243	molybdopterin cofactor binding
FORC23_3274	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FORC23_3275	COG3850	Histidine kinase
FORC23_3276	COG2197	response regulator
FORC23_3279	COG2195	Cleaves the N-terminal amino acid of tripeptides
FORC23_3283	COG0840	transmembrane signaling receptor activity
FORC23_3285	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC23_3287	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FORC23_3288	COG2814	Major facilitator Superfamily
FORC23_3289	COG0840	transmembrane signaling receptor activity
FORC23_3290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FORC23_3291	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC23_3295	COG2897	thiosulfate sulfurtransferase activity
FORC23_3298	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FORC23_3300	COG0302	gtp cyclohydrolase
FORC23_3301	COG1914	H( )-stimulated, divalent metal cation uptake system
FORC23_3303	COG0038	chloride channel
FORC23_3306	COG4989	oxidoreductase activity
FORC23_3309	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FORC23_3309	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FORC23_3310	COG0516	GMP reductase activity
FORC23_3311	COG2801	Transposase and inactivated derivatives
FORC23_3312	COG2963	transposase activity
FORC23_3313	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FORC23_3320	COG1447	Phosphotransferase system cellobiose-specific component IIA
FORC23_3321	COG2723	6-phospho-beta-galactosidase activity
FORC23_3322	COG1917	Cupin 2, conserved barrel domain protein
FORC23_3322	COG2169	Transcriptional regulator
FORC23_3324	COG1070	Carbohydrate kinase
FORC23_3325	COG4806	L-rhamnose isomerase
FORC23_3326	COG0235	Class ii aldolase
FORC23_3327	COG1454	alcohol dehydrogenase
FORC23_3329	COG0656	L-ascorbic acid biosynthetic process
FORC23_3330	COG1979	alcohol dehydrogenase
FORC23_3331	COG2207	Transcriptional regulator
FORC23_3335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC23_3345	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FORC23_3348	COG3474	cytochrome
FORC23_3350	COG0789	Transcriptional regulator
FORC23_3351	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FORC23_3352	COG0384	phenazine biosynthesis protein PhzF
FORC23_3353	COG1294	oxidase, subunit
FORC23_3354	COG1271	oxidase subunit
FORC23_3355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FORC23_3356	COG0110	maltose O-acetyltransferase activity
FORC23_3357	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FORC23_3357	COG3264	Mechanosensitive ion channel
FORC23_3360	COG4999	Histidine kinase
FORC23_3360	COG3437	response regulator, receiver
FORC23_3360	COG2205	protein histidine kinase activity
FORC23_3360	COG3850	Histidine kinase
FORC23_3363	COG1024	Enoyl-CoA hydratase
FORC23_3364	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC23_3365	COG1960	acyl-CoA dehydrogenase activity
FORC23_3367	COG0183	Belongs to the thiolase family
FORC23_3369	COG1960	acyl-CoA dehydrogenase activity
FORC23_3370	COG1024	Enoyl-CoA hydratase
FORC23_3373	COG1028	Short-chain dehydrogenase reductase Sdr
FORC23_3374	COG3706	GGDEF domain
FORC23_3375	COG1309	transcriptional regulator
FORC23_3376	COG1012	belongs to the aldehyde dehydrogenase family
FORC23_3379	COG4176	ABC-type proline glycine betaine transport system permease component
FORC23_3380	COG4175	Glycine betaine
FORC23_3380	COG0517	IMP dehydrogenase activity
FORC23_3383	COG0330	HflC and HflK could
FORC23_3385	COG5001	Diguanylate cyclase
FORC23_3385	COG3300	MHYT domain
FORC23_3387	COG0784	Response regulator, receiver
FORC23_3387	COG2205	protein histidine kinase activity
FORC23_3397	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FORC23_3398	COG5001	Diguanylate cyclase
FORC23_3399	COG1869	D-ribose catabolic process
FORC23_3400	COG1129	ABC transporter
FORC23_3401	COG1172	Belongs to the binding-protein-dependent transport system permease family
FORC23_3402	COG1879	ABC-type sugar transport system periplasmic component
FORC23_3403	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC23_3404	COG1609	Transcriptional regulator
FORC23_3407	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FORC23_3409	COG4607	ABC-type enterochelin transport system periplasmic component
FORC23_3410	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC23_3411	COG4605	iron ion homeostasis
FORC23_3412	COG4604	ABC transporter, ATP-binding protein
FORC23_3413	COG0789	Transcriptional regulator
FORC23_3415	COG1629	transport
FORC23_3415	COG4771	TonB-dependent receptor
FORC23_3422	COG1289	transmembrane transporter activity
FORC23_3423	COG0210	DNA helicase
FORC23_3424	COG1803	Methylglyoxal synthase
FORC23_3425	COG1879	ABC-type sugar transport system periplasmic component
FORC23_3426	COG2198	Histidine kinase
FORC23_3426	COG2205	protein histidine kinase activity
FORC23_3426	COG0784	Response regulator, receiver
FORC23_3429	COG0745	RESPONSE REGULATOR receiver
FORC23_3430	COG3119	arylsulfatase activity
FORC23_3431	COG3119	arylsulfatase activity
FORC23_3434	COG3119	arylsulfatase activity
FORC23_3435	COG0641	radical SAM
FORC23_3436	COG0714	Associated with various cellular activities
FORC23_3442	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FORC23_3443	COG0583	DNA-binding transcription factor activity
FORC23_3444	COG1597	lipid kinase activity
FORC23_3445	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC23_3448	COG0641	radical SAM
FORC23_3453	COG0501	Belongs to the peptidase M48B family
FORC23_3454	COG1704	LemA family
FORC23_3455	COG3069	C4-dicarboxylate transmembrane transporter activity
FORC23_3461	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FORC23_3465	COG2207	Transcriptional regulator
FORC23_3470	COG4964	Belongs to the GSP D family
FORC23_3482	COG0583	DNA-binding transcription factor activity
FORC23_3486	COG5001	Diguanylate cyclase
FORC23_3486	COG3300	MHYT domain
FORC23_3487	COG2197	response regulator
FORC23_3488	COG3706	GGDEF domain
FORC23_3490	COG2197	response regulator
FORC23_3493	COG0784	Response regulator, receiver
FORC23_3493	COG0835	chemotaxis
FORC23_3496	COG2962	Rard protein
FORC23_3498	COG0671	phosphoesterase, PA-phosphatase related
FORC23_3501	COG2076	Multidrug Resistance protein
FORC23_3507	COG0471	metal ion transport
FORC23_3508	COG3290	protein histidine kinase activity
FORC23_3509	COG4565	transcriptional regulatory protein
FORC23_3511	COG0069	glutamate synthase activity
FORC23_3511	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FORC23_3512	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FORC23_3517	COG1902	pentaerythritol trinitrate reductase activity
FORC23_3521	COG2239	Acts as a magnesium transporter
FORC23_3527	COG0242	peptide deformylase activity
FORC23_3535	COG2176	DNA-directed DNA polymerase activity
FORC23_3536	COG0583	DNA-binding transcription factor activity
FORC23_3537	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FORC23_3538	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC23_3543	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC23_3543	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FORC23_3544	COG0509	glycine decarboxylation via glycine cleavage system
FORC23_3545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FORC23_3553	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC23_3553	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FORC23_3553	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC23_3554	COG1105	Belongs to the carbohydrate kinase PfkB family
FORC23_3555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC23_3555	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC23_3556	COG1609	Transcriptional regulator
FORC23_3559	COG2199	diguanylate cyclase activity
FORC23_3559	COG2200	EAL domain
FORC23_3559	COG2203	Gaf domain
FORC23_3560	COG0765	amino acid transport
FORC23_3561	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC23_3562	COG0765	amino acid transport
FORC23_3563	COG1126	abc transporter atp-binding protein
FORC23_3564	COG0469	pyruvate kinase activity
FORC23_3565	COG2271	Major facilitator Superfamily
FORC23_3566	COG1840	ABC-type Fe3 transport system, periplasmic component
FORC23_3570	COG1979	alcohol dehydrogenase
FORC23_3571	COG2207	Transcriptional regulator
FORC23_3573	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FORC23_3574	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FORC23_3575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC23_3578	COG0784	Response regulator, receiver
FORC23_3578	COG3437	response regulator, receiver
FORC23_3579	COG0546	phosphoglycolate phosphatase activity
FORC23_3581	COG0840	transmembrane signaling receptor activity
FORC23_3582	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FORC23_3583	COG0513	Belongs to the DEAD box helicase family
FORC23_3584	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FORC23_3587	COG3038	cytochrome b561
FORC23_3588	COG2353	YceI-like domain
FORC23_3589	COG2116	formate transmembrane transporter activity
FORC23_3590	COG0583	DNA-binding transcription factor activity
FORC23_3592	COG3593	DNA synthesis involved in DNA repair
FORC23_3593	COG0737	Belongs to the 5'-nucleotidase family
FORC23_3594	COG0861	Integral membrane protein TerC family
FORC23_3597	COG2267	carboxylic ester hydrolase activity
FORC23_3598	COG2067	long-chain fatty acid transport protein
FORC23_3601	COG2050	protein possibly involved in aromatic compounds catabolism
FORC23_3603	COG4533	DNA binding
FORC23_3608	COG0484	heat shock protein binding
FORC23_3610	COG3300	MHYT domain
FORC23_3610	COG5001	Diguanylate cyclase
FORC23_3611	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FORC23_3613	COG4181	ATPase activity
FORC23_3614	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FORC23_3616	COG1984	allophanate hydrolase subunit 2
FORC23_3617	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FORC23_3618	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FORC23_3619	COG5002	protein histidine kinase activity
FORC23_3619	COG5001	Diguanylate cyclase
FORC23_3619	COG3447	MASE1 domain protein
FORC23_3620	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FORC23_3621	COG1629	transport
FORC23_3621	COG4771	TonB-dependent receptor
FORC23_3622	COG0583	DNA-binding transcription factor activity
FORC23_3623	COG1042	CoA-binding domain protein
FORC23_3623	COG0045	succinate-CoA ligase (ADP-forming) activity
FORC23_3623	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC23_3625	COG1181	Belongs to the D-alanine--D-alanine ligase family
FORC23_3627	COG0023	Translation Initiation Factor
FORC23_3629	COG0583	DNA-binding transcription factor activity
FORC23_3631	COG0589	response to stress
FORC23_3632	COG3140	Belongs to the UPF0181 family
FORC23_3637	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FORC23_3638	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FORC23_3641	COG0745	RESPONSE REGULATOR receiver
FORC23_3641	COG3706	GGDEF domain
FORC23_3643	COG5001	Diguanylate cyclase
FORC23_3643	COG2203	Gaf domain
FORC23_3643	COG3706	GGDEF domain
FORC23_3643	COG4251	negative regulation of phosphorylation
FORC23_3645	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FORC23_3646	COG4149	molybdate abc transporter
FORC23_3647	COG0725	ABC transporter, periplasmic molybdate-binding protein
FORC23_3648	COG1492	cobalamin metabolic process
FORC23_3649	COG3111	PFAM Bacterial OB fold (BOF) protein
FORC23_3651	COG0189	ligase activity
FORC23_3651	COG4067	protein conserved in archaea
FORC23_3654	COG0534	Mate efflux family protein
FORC23_3655	COG0602	queuosine metabolic process
FORC23_3656	COG1328	CTP reductase activity
FORC23_3659	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC23_3665	COG0243	molybdopterin cofactor binding
FORC23_3666	COG0583	DNA-binding transcription factor activity
FORC23_3667	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FORC23_3669	COG2197	response regulator
FORC23_3670	COG3851	Histidine kinase
FORC23_3671	COG2271	Major facilitator Superfamily
FORC23_3676	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FORC23_3677	COG3118	belongs to the thioredoxin family
FORC23_3678	COG2814	Major facilitator Superfamily
FORC23_3680	COG0534	Mate efflux family protein
FORC23_3686	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FORC23_3690	COG2116	formate transmembrane transporter activity
FORC23_3691	COG2146	nitrite reductase [NAD(P)H] activity
FORC23_3692	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC23_3693	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FORC23_3699	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FORC23_3699	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FORC23_3705	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FORC23_3708	COG0277	FAD linked oxidase domain protein
FORC23_3709	COG0583	DNA-binding transcription factor activity
FORC23_3710	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FORC23_3713	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FORC23_3715	COG1288	antiporter activity
FORC23_3717	COG2814	Major facilitator Superfamily
FORC23_3719	COG3040	lipid binding
FORC23_3723	COG0419	ATPase involved in DNA repair
FORC23_3724	COG0420	3'-5' exonuclease activity
FORC23_3727	COG3501	Rhs element vgr protein
FORC23_3738	COG0631	protein serine/threonine phosphatase activity
FORC23_3745	COG0515	serine threonine protein kinase
FORC23_3745	COG2815	serine threonine protein kinase
FORC23_3756	COG2146	nitrite reductase [NAD(P)H] activity
FORC23_3756	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FORC23_3757	COG1116	anion transmembrane transporter activity
FORC23_3758	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FORC23_3759	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FORC23_3760	COG3707	response regulator
FORC23_3763	COG1648	precorrin-2 dehydrogenase activity
FORC23_3763	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FORC23_3764	COG0243	molybdopterin cofactor binding
FORC23_3765	COG0456	acetyltransferase
FORC23_3766	COG0814	amino acid
FORC23_3767	COG3706	GGDEF domain
FORC23_3767	COG0745	RESPONSE REGULATOR receiver
FORC23_3771	COG1785	Belongs to the alkaline phosphatase family
FORC23_3774	COG0745	RESPONSE REGULATOR receiver
FORC23_3779	COG2847	Copper chaperone PCu(A)C
FORC23_3780	COG0443	Heat shock 70 kDa protein
FORC23_3787	COG0625	glutathione transferase activity
FORC23_3790	COG4160	amino acid transport
FORC23_3791	COG4215	(ABC) transporter
FORC23_3792	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC23_3793	COG1126	abc transporter atp-binding protein
FORC23_3799	COG1902	pentaerythritol trinitrate reductase activity
FORC23_3800	COG0109	protoheme IX farnesyltransferase activity
FORC23_3801	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FORC23_3802	COG1845	cytochrome c oxidase, subunit III
FORC23_3803	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FORC23_3804	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC23_3805	COG1028	Short-chain dehydrogenase reductase Sdr
FORC23_3807	COG1024	Enoyl-CoA hydratase
FORC23_3808	COG1024	Enoyl-CoA hydratase
FORC23_3811	COG0183	Belongs to the thiolase family
FORC23_3813	COG1960	acyl-CoA dehydrogenase activity
FORC23_3814	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FORC23_3815	COG1024	Enoyl-CoA hydratase
FORC23_3817	COG5413	integral membrane protein
FORC23_3820	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FORC23_3821	COG5001	Diguanylate cyclase
FORC23_3822	COG0513	Belongs to the DEAD box helicase family
FORC23_3823	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FORC23_3826	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC23_3833	COG0641	radical SAM
FORC23_3837	COG0840	transmembrane signaling receptor activity
FORC23_3838	COG1119	ATPase activity
FORC23_3839	COG2200	EAL domain
FORC23_3843	COG0513	Belongs to the DEAD box helicase family
FORC23_3844	COG0523	cobalamin synthesis protein
FORC23_3846	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FORC23_3848	COG0133	tryptophan synthase activity
FORC23_3849	COG4628	conserved protein (DUF2132)
FORC23_3850	COG0513	Belongs to the DEAD box helicase family
FORC23_3851	COG3530	Putative quorum-sensing-regulated virulence factor
FORC23_3855	COG2154	pterin-4-alpha-carbinolamine dehydratase
FORC23_3856	COG3186	Phenylalanine-4-hydroxylase
FORC23_3857	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FORC23_3858	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC23_3866	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FORC23_3867	COG1454	alcohol dehydrogenase
FORC23_3868	COG2133	pyrroloquinoline quinone binding
FORC23_3870	COG0783	Belongs to the Dps family
FORC23_3871	COG0840	transmembrane signaling receptor activity
FORC23_3873	COG0577	efflux transmembrane transporter activity
FORC23_3873	COG1136	(ABC) transporter
FORC23_3877	COG2199	diguanylate cyclase activity
FORC23_3879	COG3036	rescue of stalled ribosome
FORC23_3885	COG0545	Peptidyl-prolyl cis-trans isomerase
FORC23_3886	COG0109	protoheme IX farnesyltransferase activity
FORC23_3887	COG1612	heme a metabolic process
FORC23_3891	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FORC23_3893	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FORC23_3894	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FORC23_3896	COG1280	lysine exporter protein (LysE YggA)
FORC23_3897	COG2207	Transcriptional regulator
FORC23_3902	COG0697	spore germination
FORC23_3905	COG2814	Major facilitator Superfamily
FORC23_3906	COG0583	DNA-binding transcription factor activity
FORC23_3907	COG5001	Diguanylate cyclase
FORC23_3908	COG0739	heme binding
FORC23_3915	COG0814	amino acid
FORC23_3919	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC23_3920	COG1072	(Pantothenic acid kinase))
FORC23_3922	COG1063	alcohol dehydrogenase
FORC23_3923	COG2213	PTS system mannitol-specific
FORC23_3924	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC23_3927	COG0798	PFAM Bile acid sodium symporter
FORC23_3929	COG1881	PFAM PEBP family protein
FORC23_3931	COG2706	6-phosphogluconolactonase activity
FORC23_3934	COG1131	(ABC) transporter
FORC23_3935	COG0842	Transport permease protein
FORC23_3938	COG3383	formate dehydrogenase (NAD+) activity
FORC23_3942	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FORC23_3946	COG2203	Gaf domain
FORC23_3946	COG2199	diguanylate cyclase activity
FORC23_3948	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FORC23_3950	COG2067	long-chain fatty acid transport protein
FORC23_3952	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FORC23_3954	COG1505	serine-type exopeptidase activity
FORC23_3955	COG0488	(ABC) transporter
FORC23_3956	COG0589	response to stress
FORC23_3957	COG2249	NAD(P)H dehydrogenase (quinone) activity
FORC23_3961	COG0366	Alpha amylase catalytic
FORC23_3963	COG4934	collagen metabolic process
FORC23_3965	COG0583	DNA-binding transcription factor activity
FORC23_3966	COG0783	Belongs to the Dps family
FORC23_3967	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FORC23_3972	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
FORC23_3972	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FORC23_3974	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FORC23_3975	COG0835	chemotaxis
FORC23_3975	COG0784	Response regulator, receiver
FORC23_3977	COG0748	coenzyme F420 binding
FORC23_3978	COG3721	Heme iron utilization protein
FORC23_3980	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FORC23_3981	COG0811	peptide transport
FORC23_3982	COG0848	biopolymer transport protein
FORC23_3984	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC23_3985	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FORC23_3993	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FORC23_3994	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FORC23_3995	COG0633	Ferredoxin
FORC23_3995	COG0633	Ferredoxin
FORC23_3995	COG3217	Mosc domain protein beta barrel domain protein
FORC23_3995	COG3217	Mosc domain protein beta barrel domain protein
FORC23_3996	COG0401	homolog of Blt101
FORC23_3997	COG0418	dihydroorotase activity
FORC23_3998	COG2354	Protein conserved in bacteria
FORC23_4004	COG3833	ABC-type maltose transport systems, permease component
FORC23_4005	COG1175	transmembrane transport
FORC23_4007	COG3842	ATPase activity
FORC23_4020	COG1309	transcriptional regulator
FORC23_4021	COG2130	NADP-dependent
FORC23_4023	COG0753	catalase activity
FORC23_4024	COG2084	Dehydrogenase
FORC23_4025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC23_4026	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC23_4028	COG2207	Transcriptional regulator
FORC23_4029	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FORC23_4029	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC23_4029	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FORC23_4032	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FORC23_4033	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FORC23_4035	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FORC23_4036	COG0569	domain protein
FORC23_4038	COG5002	protein histidine kinase activity
FORC23_4039	COG1132	(ABC) transporter
FORC23_4040	COG4774	siderophore transport
FORC23_4041	COG1120	ATPase activity
FORC23_4042	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FORC23_4052	COG2197	response regulator
FORC23_4054	COG0840	transmembrane signaling receptor activity
FORC23_4055	COG0714	Associated with various cellular activities
FORC23_4059	COG2304	oxidoreductase activity
FORC23_4062	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FORC23_4063	COG0581	inorganic phosphate transmembrane transporter activity
FORC23_4064	COG0573	inorganic phosphate transmembrane transporter activity
FORC23_4065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FORC23_4070	COG4771	TonB-dependent receptor
FORC23_4071	COG1770	oligopeptidase
FORC23_4072	COG0513	Belongs to the DEAD box helicase family
FORC23_4074	COG1388	LysM domain
FORC23_4074	COG1376	ErfK ybiS ycfS ynhG family protein
FORC23_4075	COG0415	Belongs to the DNA photolyase family
FORC23_4076	COG0789	Transcriptional regulator
FORC23_4077	COG3272	Protein of unknown function (DUF1722)
FORC23_4078	COG0813	purine-nucleoside phosphorylase activity
FORC23_4081	COG3706	GGDEF domain
FORC23_4083	COG1566	PFAM secretion protein HlyD family protein
FORC23_4084	COG4720	Psort location CytoplasmicMembrane, score
FORC23_4085	COG1122	ATPase activity
FORC23_4088	COG0348	domain, Protein
FORC23_4089	COG0437	4 iron, 4 sulfur cluster binding
FORC23_4090	COG1247	-acetyltransferase
FORC23_4095	COG1067	ATP-dependent peptidase activity
FORC23_4097	COG4172	Belongs to the ABC transporter superfamily
FORC23_4098	COG1505	serine-type exopeptidase activity
FORC23_4099	COG0583	DNA-binding transcription factor activity
FORC23_4100	COG1620	l-lactate permease
FORC23_4101	COG1304	FMN binding
FORC23_4103	COG0668	transmembrane transport
FORC23_4110	COG1063	alcohol dehydrogenase
FORC23_4111	COG0156	8-amino-7-oxononanoate synthase activity
FORC23_4113	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FORC23_4117	COG0745	RESPONSE REGULATOR receiver
FORC23_4122	COG0346	lactoylglutathione lyase activity
FORC23_4125	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FORC23_4133	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FORC23_4136	COG2204	response regulator
FORC23_4141	COG1987	bacterial-type flagellum assembly
FORC23_4143	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FORC23_4146	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FORC23_4150	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FORC23_4151	COG1516	flagellar protein fliS
FORC23_4154	COG1580	Controls the rotational direction of flagella during chemotaxis
FORC23_4155	COG1191	sigma factor activity
FORC23_4156	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FORC23_4157	COG1360	Flagellar Motor Protein
FORC23_4167	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FORC23_4168	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FORC23_4170	COG0454	-acetyltransferase
FORC23_4172	COG2814	Major facilitator Superfamily
FORC23_4180	COG0628	permease
FORC23_4181	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FORC23_4183	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FORC23_4185	COG4628	conserved protein (DUF2132)
FORC23_4186	COG0583	DNA-binding transcription factor activity
FORC23_4191	COG1686	Belongs to the peptidase S11 family
FORC23_4195	COG3397	chitin binding
FORC23_4196	COG4667	esterase of the alpha-beta hydrolase superfamily
FORC23_4197	COG2095	MarC family integral membrane protein
FORC23_4200	COG1596	polysaccharide export
FORC23_4201	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FORC23_4205	COG0583	DNA-binding transcription factor activity
FORC23_4207	COG1301	dicarboxylic acid transport
FORC23_4208	COG3339	Conserved Protein
FORC23_4209	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FORC23_4210	COG0700	Nucleoside recognition
FORC23_4211	COG3366	ferrous iron transmembrane transporter activity
FORC23_4213	COG0366	Alpha amylase catalytic
FORC23_4214	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FORC23_4215	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FORC23_4216	COG1640	4-alpha-glucanotransferase
FORC23_4217	COG0058	SHG alpha-glucan phosphorylase activity
FORC23_4218	COG2909	trisaccharide binding
FORC23_4221	COG1999	signal sequence binding
FORC23_4223	COG1263	PTS System
FORC23_4223	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC23_4224	COG1162	GTPase activity
FORC23_4225	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FORC23_4227	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FORC23_4229	COG0531	amino acid
FORC23_4230	COG1982	Orn Lys Arg decarboxylase major
FORC23_4234	COG2356	endonuclease I
FORC23_4238	COG4580	involved in the transport of maltose and maltodextrins
FORC23_4241	COG2814	Major facilitator Superfamily
FORC23_4244	COG0612	Peptidase, M16
FORC23_4245	COG0840	transmembrane signaling receptor activity
FORC23_4246	COG1120	ATPase activity
FORC23_4247	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC23_4248	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FORC23_4249	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FORC23_4250	COG4772	TonB-dependent receptor
FORC23_4254	COG2814	Major facilitator Superfamily
FORC23_4255	COG4264	IucA IucC family
FORC23_4256	COG0019	diaminopimelate decarboxylase activity
FORC23_4257	COG1653	transport
FORC23_4259	COG0745	RESPONSE REGULATOR receiver
FORC23_4263	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FORC23_4269	COG1764	response to oxidative stress
FORC23_4270	COG1846	Transcriptional regulator
FORC23_4271	COG0450	alkyl hydroperoxide reductase
FORC23_4272	COG3634	alkyl hydroperoxide reductase activity
FORC23_4279	COG1595	DNA-templated transcription, initiation
FORC23_4282	COG0583	DNA-binding transcription factor activity
FORC23_4283	COG1486	melibiose metabolic process
FORC23_4286	COG2258	MOSC domain
FORC23_4287	COG0513	Belongs to the DEAD box helicase family
FORC23_4289	COG2186	Transcriptional regulator
FORC23_4291	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FORC23_4293	COG0246	Mannitol dehydrogenase
FORC23_4294	COG1904	glucuronate isomerase
FORC23_4295	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FORC23_4296	COG0800	Aldolase
FORC23_4299	COG2207	Transcriptional regulator
FORC23_4301	COG1132	(ABC) transporter
FORC23_4310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FORC23_4315	COG0259	pyridoxamine-phosphate oxidase activity
FORC23_4325	COG4166	transmembrane transport
FORC23_4328	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FORC23_4329	COG1263	PTS System
FORC23_4329	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FORC23_4330	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FORC23_4331	COG3340	Belongs to the peptidase S51 family
FORC23_4335	COG1444	tRNA N-acetyltransferase activity