locus-tag	class	description
JK088_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JK088_00010	COG0592	DNA-directed DNA polymerase activity
JK088_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JK088_00020	COG0187	DNA topoisomerase II activity
JK088_00030	COG0071	Belongs to the small heat shock protein (HSP20) family
JK088_00035	COG3977	Valine--pyruvate aminotransferase
JK088_00040	COG0366	Alpha amylase catalytic
JK088_00045	COG0751	glycine-tRNA ligase activity
JK088_00050	COG0752	glycyl-tRNA synthetase alpha subunit
JK088_00055	COG2119	membrane
JK088_00065	COG0425	Belongs to the sulfur carrier protein TusA family
JK088_00080	COG0604	alcohol dehydrogenase
JK088_00085	COG0183	Belongs to the thiolase family
JK088_00090	COG1024	Enoyl-CoA hydratase
JK088_00090	COG1250	3-hydroxyacyl-CoA dehydrogenase
JK088_00095	COG1739	Uncharacterized protein family UPF0029
JK088_00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JK088_00140	COG0583	DNA-binding transcription factor activity
JK088_00145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JK088_00150	COG2960	long-chain fatty acid transporting porin activity
JK088_00155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JK088_00160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK088_00215	COG0747	negative chemotaxis
JK088_00220	COG0601	transmembrane transport
JK088_00225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JK088_00260	COG1609	Transcriptional regulator
JK088_00265	COG0583	DNA-binding transcription factor activity
JK088_00280	COG0129	dihydroxy-acid dehydratase activity
JK088_00285	COG3265	gluconokinase activity
JK088_00290	COG2610	gluconate transmembrane transporter activity
JK088_00295	COG0800	Aldolase
JK088_00300	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JK088_00305	COG0583	DNA-binding transcription factor activity
JK088_00310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JK088_00315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JK088_00320	COG0339	signal peptide processing
JK088_00325	COG1522	sequence-specific DNA binding
JK088_00330	COG5001	Diguanylate cyclase
JK088_00330	COG5002	protein histidine kinase activity
JK088_00335	COG0742	ribosomal rna small subunit methyltransferase
JK088_00350	COG0589	response to stress
JK088_00355	COG1528	Iron-storage protein
JK088_00365	COG2081	HI0933 family
JK088_00375	COG2823	Periplasmic or secreted lipoprotein
JK088_00395	COG1597	lipid kinase activity
JK088_00425	COG0628	permease
JK088_00440	COG1322	Protein conserved in bacteria
JK088_00445	COG2226	methyltransferase
JK088_00450	COG3165	ubiquinone biosynthetic process from chorismate
JK088_00455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JK088_00460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JK088_00465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JK088_00470	COG0805	protein transport
JK088_00475	COG0084	hydrolase, TatD family'
JK088_00490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JK088_00490	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JK088_00495	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JK088_00530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JK088_00540	COG2204	response regulator
JK088_00545	COG3852	Histidine kinase
JK088_00555	COG0174	glutamine synthetase
JK088_00560	COG1217	gtp-binding protein TYPA
JK088_00575	COG1295	ribonuclease BN
JK088_00580	COG1490	D-aminoacyl-tRNA deacylase activity
JK088_00585	COG0456	acetyltransferase
JK088_00595	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JK088_00600	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JK088_00605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JK088_00610	COG3031	protein transport across the cell outer membrane
JK088_00620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JK088_00625	COG1459	type II secretion system
JK088_00630	COG2165	general secretion pathway protein
JK088_00635	COG2165	general secretion pathway protein
JK088_00640	COG2165	general secretion pathway protein
JK088_00645	COG4795	General secretion pathway protein
JK088_00650	COG3156	type II secretion system protein K
JK088_00655	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JK088_00660	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JK088_00670	COG1218	3'(2'),5'-bisphosphate nucleotidase
JK088_00675	COG0494	nUDIX hydrolase
JK088_00680	COG0316	Belongs to the HesB IscA family
JK088_00680	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JK088_00685	COG1040	competence protein
JK088_00690	COG0596	Alpha beta hydrolase
JK088_00700	COG2183	response to ionizing radiation
JK088_00710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JK088_00730	COG2233	PERMEase
JK088_00735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JK088_00740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JK088_00745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JK088_00750	COG1758	RNA polymerase activity
JK088_00755	COG0194	GDP metabolic process
JK088_00770	COG0848	biopolymer transport protein
JK088_00775	COG0811	peptide transport
JK088_00795	COG4174	ABC transporter (Permease)
JK088_00800	COG4239	(ABC) transporter, permease
JK088_00805	COG0747	negative chemotaxis
JK088_00810	COG0444	Belongs to the ABC transporter superfamily
JK088_00815	COG4608	Belongs to the ABC transporter superfamily
JK088_00825	COG1561	YicC-like family, N-terminal region
JK088_00830	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JK088_00835	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JK088_00840	COG1560	Kdo2-lipid A biosynthetic process
JK088_00845	COG1309	transcriptional regulator
JK088_00850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JK088_00860	COG2003	Belongs to the UPF0758 family
JK088_00865	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JK088_00880	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JK088_00905	COG0463	Glycosyl transferase, family 2
JK088_00910	COG0859	PFAM glycosyl transferase family 9
JK088_00915	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JK088_00920	COG3642	lipopolysaccharide core region biosynthetic process
JK088_00940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JK088_00965	COG1021	2,3-dihydroxybenzoate-AMP ligase
JK088_00970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JK088_00985	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JK088_00990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JK088_00995	COG2089	acid synthase
JK088_01005	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JK088_01010	COG1083	cytidylyl-transferase
JK088_01020	COG1519	Transferase
JK088_01025	COG0859	PFAM glycosyl transferase family 9
JK088_01030	COG1560	Kdo2-lipid A biosynthetic process
JK088_01075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JK088_01085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JK088_01100	COG0438	transferase activity, transferring glycosyl groups
JK088_01130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JK088_01185	COG0149	triose-phosphate isomerase activity
JK088_01210	COG1494	fructose-1,6-bisphosphatase
JK088_01215	COG3074	FtsZ-dependent cytokinesis
JK088_01220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JK088_01225	COG1575	Belongs to the MenA family. Type 1 subfamily
JK088_01255	COG2003	Belongs to the UPF0758 family
JK088_01270	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JK088_01275	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JK088_01285	COG1609	Transcriptional regulator
JK088_01290	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JK088_01295	COG0254	rRNA binding
JK088_01305	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JK088_01310	COG0088	Forms part of the polypeptide exit tunnel
JK088_01320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JK088_01325	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JK088_01330	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JK088_01335	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JK088_01345	COG0255	Belongs to the universal ribosomal protein uL29 family
JK088_01350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JK088_01355	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JK088_01360	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JK088_01365	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JK088_01370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JK088_01375	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JK088_01380	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JK088_01395	COG1841	ribosomal large subunit assembly
JK088_01400	COG0200	Binds to the 23S rRNA
JK088_01405	COG0201	protein transport
JK088_01410	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JK088_01415	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JK088_01420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JK088_01430	COG0202	RNA polymerase activity
JK088_01435	COG0203	ribosomal protein L17
JK088_01445	COG0545	Peptidyl-prolyl cis-trans isomerase
JK088_01455	COG2153	protein acetylation
JK088_01460	COG0513	Belongs to the DEAD box helicase family
JK088_01470	COG0737	Belongs to the 5'-nucleotidase family
JK088_01475	COG1648	precorrin-2 dehydrogenase activity
JK088_01475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JK088_01480	COG0175	sulfate reduction
JK088_01485	COG2895	sulfate adenylyltransferase (ATP) activity
JK088_01490	COG3273	potassium ion transport
JK088_01490	COG0471	metal ion transport
JK088_01495	COG0529	Catalyzes the synthesis of activated sulfate
JK088_01515	COG4181	ATPase activity
JK088_01530	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JK088_01540	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JK088_01545	COG0729	surface antigen
JK088_01550	COG2911	Protein conserved in bacteria
JK088_01555	COG2105	PFAM AIG2 family protein
JK088_01565	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JK088_01570	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JK088_01575	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JK088_01580	COG0163	prenyltransferase activity
JK088_01585	COG4143	(ABC) transporter
JK088_01590	COG1178	ABC-type Fe3 transport system permease component
JK088_01595	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JK088_01610	COG2358	TRAP transporter, solute receptor (TAXI family
JK088_01620	COG0039	L-malate dehydrogenase activity
JK088_01630	COG0142	geranyltranstransferase activity
JK088_01635	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JK088_01645	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JK088_01650	COG2966	Psort location CytoplasmicMembrane, score
JK088_01665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JK088_01670	COG2967	ApaG domain
JK088_01675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JK088_01680	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JK088_01685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JK088_01690	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JK088_01695	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JK088_01705	COG0066	3-isopropylmalate dehydratase activity
JK088_01710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JK088_01715	COG0473	3-isopropylmalate dehydrogenase activity
JK088_01720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JK088_01740	COG0583	DNA-binding transcription factor activity
JK088_01745	COG1022	Amp-dependent synthetase and ligase
JK088_01750	COG0028	Belongs to the TPP enzyme family
JK088_01755	COG0440	acetolactate synthase activity
JK088_01770	COG0469	pyruvate kinase activity
JK088_01775	COG1349	DNA-binding transcription factor activity
JK088_01780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JK088_01795	COG5002	protein histidine kinase activity
JK088_01800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JK088_01805	COG3722	fumarate hydratase activity
JK088_01810	COG0246	Mannitol dehydrogenase
JK088_01815	COG2213	PTS system mannitol-specific
JK088_01815	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JK088_01845	COG1464	Belongs to the NlpA lipoprotein family
JK088_01905	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JK088_01935	COG0358	DNA primase activity
JK088_01940	COG1610	YqeY-like protein
JK088_01945	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JK088_01950	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JK088_01955	COG0596	Alpha beta hydrolase
JK088_01960	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JK088_01965	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JK088_01970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JK088_01975	COG1968	undecaprenyl-diphosphatase activity
JK088_01980	COG0617	tRNA 3'-terminal CCA addition
JK088_01985	COG3409	Peptidoglycan-binding domain 1 protein
JK088_01985	COG3267	Type II secretory pathway component ExeA
JK088_01995	COG4991	sh3 domain protein
JK088_02000	COG0306	phosphate transporter
JK088_02005	COG1392	Phosphate transport regulator
JK088_02010	COG3025	triphosphatase activity
JK088_02025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JK088_02030	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JK088_02030	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JK088_02035	COG1538	Outer membrane efflux protein
JK088_02040	COG0494	nUDIX hydrolase
JK088_02045	COG3151	Protein conserved in bacteria
JK088_02055	COG3150	esterase
JK088_02065	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JK088_02070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JK088_02080	COG3105	Protein conserved in bacteria
JK088_02085	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JK088_02090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JK088_02095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JK088_02100	COG0723	plastoquinol--plastocyanin reductase activity
JK088_02105	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JK088_02110	COG2857	Cytochrome c1
JK088_02115	COG0625	glutathione transferase activity
JK088_02120	COG2969	positive regulation of protein catabolic process
JK088_02125	COG2823	Periplasmic or secreted lipoprotein
JK088_02130	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JK088_02135	COG0792	nuclease activity
JK088_02145	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JK088_02155	COG0275	rRNA processing
JK088_02160	COG3116	cell division
JK088_02165	COG0768	penicillin binding
JK088_02170	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JK088_02175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JK088_02180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JK088_02185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JK088_02190	COG0772	Belongs to the SEDS family
JK088_02195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JK088_02200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JK088_02205	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JK088_02210	COG0849	cell division
JK088_02215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JK088_02220	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JK088_02230	COG0653	protein targeting
JK088_02235	COG0494	nUDIX hydrolase
JK088_02240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JK088_02245	COG0505	Belongs to the CarA family
JK088_02250	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JK088_02265	COG0730	response to heat
JK088_02270	COG0583	DNA-binding transcription factor activity
JK088_02275	COG2860	membrane
JK088_02280	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JK088_02290	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JK088_02300	COG0493	'glutamate synthase
JK088_02305	COG0070	glutamate synthase
JK088_02305	COG0069	glutamate synthase activity
JK088_02305	COG0067	glutamate synthase
JK088_02315	COG0070	glutamate synthase
JK088_02315	COG0067	glutamate synthase
JK088_02315	COG0069	glutamate synthase activity
JK088_02320	COG1242	4 iron, 4 sulfur cluster binding
JK088_02325	COG3706	GGDEF domain
JK088_02325	COG5001	Diguanylate cyclase
JK088_02325	COG4251	negative regulation of phosphorylation
JK088_02325	COG2203	Gaf domain
JK088_02330	COG5002	protein histidine kinase activity
JK088_02330	COG2198	Histidine kinase
JK088_02330	COG0784	Response regulator, receiver
JK088_02340	COG0745	RESPONSE REGULATOR receiver
JK088_02350	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JK088_02365	COG0083	homoserine kinase activity
JK088_02370	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JK088_02375	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
JK088_02380	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JK088_02385	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JK088_02400	COG1115	amino acid carrier protein
JK088_02405	COG3022	response to hydroperoxide
JK088_02410	COG0513	Belongs to the DEAD box helicase family
JK088_02415	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JK088_02425	COG0716	FMN binding
JK088_02430	COG4974	Belongs to the 'phage' integrase family
JK088_02435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JK088_02440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JK088_02450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JK088_02455	COG2204	response regulator
JK088_02465	COG0667	Aldo Keto reductase
JK088_02475	COG3066	DNA modification
JK088_02480	COG0494	nUDIX hydrolase
JK088_02490	COG0730	response to heat
JK088_02495	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JK088_02500	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JK088_02510	COG1283	sodium-dependent phosphate transmembrane transporter activity
JK088_02515	COG0583	DNA-binding transcription factor activity
JK088_02520	COG0640	Transcriptional regulator
JK088_02525	COG0268	Binds directly to 16S ribosomal RNA
JK088_02530	COG0728	peptidoglycan biosynthetic process
JK088_02535	COG0196	riboflavin kinase activity
JK088_02540	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JK088_02545	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JK088_02550	COG1047	Peptidyl-prolyl cis-trans
JK088_02555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JK088_02560	COG3279	Response regulator of the LytR AlgR family
JK088_02565	COG3275	phosphorelay sensor kinase activity
JK088_02570	COG1966	Carbon starvation protein
JK088_02585	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JK088_02590	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JK088_02595	COG1472	Belongs to the glycosyl hydrolase 3 family
JK088_02600	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JK088_02605	COG1605	Chorismate mutase
JK088_02605	COG0287	Prephenate dehydrogenase
JK088_02610	COG0739	heme binding
JK088_02620	COG0488	(ABC) transporter
JK088_02630	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
JK088_02635	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
JK088_02640	COG0077	Prephenate dehydratase
JK088_02640	COG1605	Chorismate mutase
JK088_02645	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JK088_02650	COG0741	lytic transglycosylase activity
JK088_02655	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JK088_02660	COG0564	pseudouridine synthase activity
JK088_02670	COG0542	response to heat
JK088_02725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JK088_02730	COG0826	peptidase U32
JK088_02735	COG2974	May be involved in recombination
JK088_02740	COG0745	RESPONSE REGULATOR receiver
JK088_02745	COG5002	protein histidine kinase activity
JK088_02755	COG0248	Ppx GppA phosphatase
JK088_02760	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JK088_02770	COG0581	inorganic phosphate transmembrane transporter activity
JK088_02775	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JK088_02780	COG0704	Plays a role in the regulation of phosphate uptake
JK088_02790	COG3142	Participates in the control of copper homeostasis
JK088_02795	COG0450	alkyl hydroperoxide reductase
JK088_02800	COG0583	DNA-binding transcription factor activity
JK088_02805	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JK088_02815	COG0517	IMP dehydrogenase activity
JK088_02825	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JK088_02830	COG0343	queuine tRNA-ribosyltransferase activity
JK088_02835	COG1862	Preprotein translocase
JK088_02840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JK088_02845	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JK088_02850	COG0483	inositol monophosphate 1-phosphatase activity
JK088_02865	COG1104	cysteine desulfurase activity
JK088_02870	COG0822	iron-sulfur transferase activity
JK088_02880	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JK088_02885	COG0443	Heat shock 70 kDa protein
JK088_02890	COG0633	Ferredoxin
JK088_02895	COG2975	iron-sulfur cluster assembly
JK088_02900	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JK088_02905	COG0105	UTP biosynthetic process
JK088_02910	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JK088_02920	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JK088_02925	COG0124	histidyl-tRNA synthetase
JK088_02930	COG2976	Protein conserved in bacteria
JK088_02935	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JK088_02940	COG1160	GTP binding
JK088_02955	COG1570	exodeoxyribonuclease VII activity
JK088_02960	COG0516	GMP reductase activity
JK088_02960	COG0517	IMP dehydrogenase activity
JK088_02965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JK088_02965	COG0519	Catalyzes the synthesis of GMP from XMP
JK088_02970	COG1757	Na H antiporter
JK088_02980	COG1584	GPR1 FUN34 yaaH family protein
JK088_03020	COG2873	o-acetylhomoserine
JK088_03025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JK088_03045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JK088_03045	COG3153	acetyltransferase
JK088_03050	COG0583	DNA-binding transcription factor activity
JK088_03080	COG1715	Restriction endonuclease
JK088_03105	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JK088_03155	COG0582	viral genome integration into host DNA
JK088_03165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JK088_03170	COG2867	negative regulation of translational initiation
JK088_03175	COG2914	Belongs to the UPF0125 (RnfH) family
JK088_03180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JK088_03185	COG0497	DNA recombination
JK088_03195	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JK088_03200	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JK088_03210	COG0443	Heat shock 70 kDa protein
JK088_03215	COG0484	heat shock protein binding
JK088_03245	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JK088_03255	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JK088_03260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JK088_03260	COG0047	phosphoribosylformylglycinamidine synthase activity
JK088_03285	COG2195	Cleaves the N-terminal amino acid of tripeptides
JK088_03290	COG2252	PERMEase
JK088_03295	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JK088_03300	COG1073	alpha beta
JK088_03310	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JK088_03315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JK088_03320	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JK088_03325	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JK088_03325	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JK088_03345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JK088_03350	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JK088_03355	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JK088_03360	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JK088_03365	COG0142	geranyltranstransferase activity
JK088_03370	COG1722	exodeoxyribonuclease VII activity
JK088_03375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JK088_03380	COG2885	chlorophyll binding
JK088_03385	COG0301	tRNA thio-modification
JK088_03385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JK088_03390	COG0583	DNA-binding transcription factor activity
JK088_03400	COG2363	Small membrane protein
JK088_03405	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JK088_03415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JK088_03420	COG1611	Belongs to the LOG family
JK088_03435	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JK088_03435	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JK088_03445	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
JK088_03450	COG1464	Belongs to the NlpA lipoprotein family
JK088_03455	COG2011	ABC-type metal ion transport system permease component
JK088_03460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JK088_03465	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JK088_03475	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JK088_03475	COG1263	PTS System
JK088_03480	COG0366	Alpha amylase catalytic
JK088_03495	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JK088_03500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JK088_03505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JK088_03510	COG0321	lipoyl(octanoyl) transferase activity
JK088_03515	COG2921	Belongs to the UPF0250 family
JK088_03520	COG1686	Belongs to the peptidase S11 family
JK088_03525	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JK088_03530	COG0772	Belongs to the SEDS family
JK088_03535	COG0768	penicillin binding
JK088_03540	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JK088_03545	COG0799	negative regulation of ribosome biogenesis
JK088_03550	COG1466	dna polymerase III delta subunit
JK088_03555	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
JK088_03565	COG2888	peptidyl-tyrosine sulfation
JK088_03575	COG4535	Mg2 and Co2 transporter CorC
JK088_03580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JK088_03585	COG1702	phosphate starvation-inducible protein PhoH
JK088_03590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JK088_03595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JK088_03710	COG0012	GTP binding
JK088_03715	COG0193	aminoacyl-tRNA hydrolase activity
JK088_03720	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JK088_03725	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JK088_03730	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JK088_03735	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JK088_03740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JK088_03745	COG2890	protein-(glutamine-N5) methyltransferase activity
JK088_03750	COG3094	Invasion gene expression up-regulator, SirB
JK088_03755	COG2912	Transglutaminase-like superfamily
JK088_03760	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JK088_03765	COG0737	Belongs to the 5'-nucleotidase family
JK088_03775	COG1187	pseudouridine synthase activity
JK088_03780	COG2840	Smr protein MutS2
JK088_03815	COG2217	Heavy metal translocating P-type atpase
JK088_03815	COG2608	mercury ion transmembrane transporter activity
JK088_03825	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JK088_03830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JK088_03880	COG0784	Response regulator, receiver
JK088_03880	COG0835	chemotaxis
JK088_03885	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JK088_03890	COG1815	bacterial-type flagellum-dependent cell motility
JK088_03895	COG1558	bacterial-type flagellum-dependent cell motility
JK088_03905	COG1749	Flagellar hook protein flgE
JK088_03910	COG4787	bacterial-type flagellum-dependent cell motility
JK088_03920	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JK088_03925	COG1706	bacterial-type flagellum-dependent cell motility
JK088_03930	COG1705	Flagellar rod assembly protein muramidase FlgJ
JK088_03930	COG3951	Flagellar rod assembly protein muramidase FlgJ
JK088_03940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JK088_03945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JK088_03950	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JK088_03955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JK088_03960	COG2190	(PTS) system
JK088_03965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JK088_03970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JK088_03975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JK088_03980	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
JK088_03985	COG3115	cell septum assembly
JK088_03990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JK088_04010	COG0330	HflC and HflK could
JK088_04015	COG3118	belongs to the thioredoxin family
JK088_04020	COG0300	oxidoreductase activity
JK088_04025	COG1090	epimerase
JK088_04055	COG0622	Phosphoesterase
JK088_04075	COG3710	Transcriptional regulator
JK088_04080	COG0326	Molecular chaperone. Has ATPase activity
JK088_04085	COG0563	adenylate kinase activity
JK088_04090	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JK088_04095	COG3104	oligopeptide transport
JK088_04100	COG0250	Participates in transcription elongation, termination and antitermination
JK088_04105	COG0367	asparagine synthase
JK088_04110	COG4651	solute:proton antiporter activity
JK088_04110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JK088_04115	COG1940	carbohydrate kinase activity
JK088_04115	COG1846	Transcriptional regulator
JK088_04120	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JK088_04125	COG1263	PTS System
JK088_04125	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JK088_04130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JK088_04135	COG0735	belongs to the Fur family
JK088_04155	COG0596	Alpha beta hydrolase
JK088_04160	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JK088_04165	COG0033	Phosphoglucomutase
JK088_04175	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JK088_04190	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JK088_04195	COG1053	succinate dehydrogenase
JK088_04200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JK088_04205	COG0567	Dehydrogenase, E1 component
JK088_04210	COG0508	dehydrogenase complex catalyzes the overall conversion of
JK088_04215	COG0045	succinate-CoA ligase (ADP-forming) activity
JK088_04225	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JK088_04230	COG1121	(ABC) transporter
JK088_04235	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JK088_04240	COG4977	sequence-specific DNA binding
JK088_04245	COG1918	ferrous iron import across plasma membrane
JK088_04265	COG0018	arginyl-trna synthetase
JK088_04270	COG3102	Protein conserved in bacteria
JK088_04285	COG0788	formyltetrahydrofolate deformylase activity
JK088_04290	COG1199	ATP-dependent helicase activity
JK088_04295	COG1214	PFAM Peptidase M22, glycoprotease
JK088_04310	COG2267	carboxylic ester hydrolase activity
JK088_04315	COG0318	PFAM AMP-dependent synthetase and ligase
JK088_04320	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JK088_04325	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JK088_04330	COG2894	cell division
JK088_04335	COG0850	regulation of cytokinetic process
JK088_04340	COG3100	YcgL domain-containing protein
JK088_04345	COG2951	lytic endotransglycosylase activity
JK088_04350	COG0583	DNA-binding transcription factor activity
JK088_04355	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JK088_04360	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JK088_04380	COG1028	Short-chain dehydrogenase reductase Sdr
JK088_04390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JK088_04415	COG2986	histidine ammonia-lyase
JK088_04420	COG1216	Glycosyl transferase, family 2
JK088_04425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JK088_04440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JK088_04445	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JK088_04480	COG1253	flavin adenine dinucleotide binding
JK088_04485	COG0513	Belongs to the DEAD box helicase family
JK088_04490	COG0569	domain protein
JK088_04495	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JK088_04510	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JK088_04515	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JK088_04520	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JK088_04525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JK088_04535	COG2204	response regulator
JK088_04550	COG0544	peptidyl-prolyl cis-trans isomerase activity
JK088_04560	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JK088_04565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JK088_04570	COG0776	regulation of translation
JK088_04575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JK088_04580	COG1555	photosystem II stabilization
JK088_04595	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JK088_04600	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
JK088_04605	COG0436	Aminotransferase
JK088_04610	COG1169	isochorismate synthase
JK088_04615	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JK088_04620	COG0596	Alpha beta hydrolase
JK088_04625	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JK088_04645	COG2855	membrane
JK088_04650	COG0477	Major facilitator Superfamily
JK088_04695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK088_04700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JK088_04725	COG1522	sequence-specific DNA binding
JK088_04735	COG1946	Acyl-CoA thioesterase
JK088_04740	COG3126	Type III secretion system lipoprotein chaperone (YscW)
JK088_04755	COG2199	diguanylate cyclase activity
JK088_04765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JK088_04770	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JK088_04775	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JK088_04780	COG0517	IMP dehydrogenase activity
JK088_04780	COG0516	GMP reductase activity
JK088_04805	COG0537	adenosine 5'-monophosphoramidase activity
JK088_04830	COG3150	esterase
JK088_04835	COG1252	NADH dehydrogenase
JK088_04850	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JK088_04860	COG4591	ABC-type transport system involved in lipoprotein release permease component
JK088_04865	COG1136	(ABC) transporter
JK088_04870	COG4591	ABC-type transport system involved in lipoprotein release permease component
JK088_04880	COG2333	competence protein COMEC
JK088_04880	COG0658	competence protein
JK088_04885	COG1132	(ABC) transporter
JK088_04890	COG1663	tetraacyldisaccharide 4'-kinase activity
JK088_04900	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JK088_04905	COG2719	SpoVR family
JK088_04910	COG2718	Belongs to the UPF0229 family
JK088_04915	COG2766	serine protein kinase
JK088_04920	COG3013	Belongs to the UPF0304 family
JK088_04930	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JK088_04940	COG1882	Formate acetyltransferase
JK088_04980	COG0708	Exodeoxyribonuclease III
JK088_04990	COG3923	Primosomal replication protein n
JK088_05000	COG1199	ATP-dependent helicase activity
JK088_05010	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JK088_05015	COG1187	pseudouridine synthase activity
JK088_05025	COG1278	Cold shock
JK088_05030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JK088_05035	COG0542	response to heat
JK088_05045	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JK088_05050	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JK088_05055	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JK088_05065	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JK088_05075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JK088_05080	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JK088_05085	COG0297	glycogen (starch) synthase activity
JK088_05105	COG3070	regulator of competence-specific genes
JK088_05110	COG1609	Transcriptional regulator
JK088_05115	COG3381	protein complex oligomerization
JK088_05120	COG0745	RESPONSE REGULATOR receiver
JK088_05125	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JK088_05130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JK088_05135	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
JK088_05140	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
JK088_05145	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JK088_05165	COG0189	ligase activity
JK088_05165	COG4067	protein conserved in archaea
JK088_05170	COG0500	methyltransferase
JK088_05175	COG4106	trans-aconitate 2-methyltransferase activity
JK088_05180	COG1801	Protein of unknown function DUF72
JK088_05185	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JK088_05190	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JK088_05195	COG0840	transmembrane signaling receptor activity
JK088_05200	COG0632	four-way junction helicase activity
JK088_05205	COG2255	four-way junction helicase activity
JK088_05210	COG1271	oxidase subunit
JK088_05215	COG1294	oxidase, subunit
JK088_05220	COG4890	Cyd operon protein YbgT
JK088_05230	COG0824	Thioesterase
JK088_05235	COG0811	peptide transport
JK088_05250	COG0823	Involved in the tonB-independent uptake of proteins
JK088_05255	COG2885	chlorophyll binding
JK088_05260	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JK088_05265	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JK088_05275	COG3766	membrane
JK088_05285	COG0754	glutathionylspermidine amidase activity
JK088_05295	COG0784	Response regulator, receiver
JK088_05295	COG5002	protein histidine kinase activity
JK088_05335	COG0840	transmembrane signaling receptor activity
JK088_05340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK088_05345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JK088_05370	COG3568	Endonuclease Exonuclease Phosphatase
JK088_05385	COG0583	DNA-binding transcription factor activity
JK088_05395	COG0686	Belongs to the AlaDH PNT family
JK088_05405	COG1674	ftsk spoiiie
JK088_05410	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JK088_05415	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JK088_05420	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JK088_05435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JK088_05440	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JK088_05445	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JK088_05450	COG0156	8-amino-7-oxononanoate synthase activity
JK088_05460	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JK088_05470	COG0501	Belongs to the peptidase M48B family
JK088_05480	COG0300	oxidoreductase activity
JK088_05495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JK088_05515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JK088_05520	COG2915	High frequency lysogenization protein hflD homolog
JK088_05525	COG0482	sulfurtransferase activity
JK088_05535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JK088_05545	COG1757	Na H antiporter
JK088_05560	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JK088_05565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JK088_05570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JK088_05575	COG0131	Imidazoleglycerol-phosphate dehydratase
JK088_05575	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JK088_05580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JK088_05585	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JK088_05590	COG0107	imidazoleglycerol-phosphate synthase activity
JK088_05595	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JK088_05595	COG0140	phosphoribosyl-ATP diphosphatase activity
JK088_05600	COG3012	SEC-C Motif Domain Protein
JK088_05605	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JK088_05610	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JK088_05615	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JK088_05620	COG0215	cysteine-tRNA ligase activity
JK088_05625	COG1435	thymidine kinase activity
JK088_05630	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JK088_05655	COG2116	formate transmembrane transporter activity
JK088_05665	COG0390	transport system, permease component
JK088_05670	COG4459	periplasmic nitrate reductase
JK088_05675	COG3005	denitrification pathway
JK088_05680	COG0243	molybdopterin cofactor binding
JK088_05695	COG1227	inorganic diphosphatase activity
JK088_05705	COG4172	Belongs to the ABC transporter superfamily
JK088_05715	COG4171	peptide transport system, permease
JK088_05730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JK088_05735	COG1842	Phage shock protein A
JK088_05745	COG1983	PspC domain protein
JK088_05750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK088_05765	COG2818	Glycosylase
JK088_05770	COG5380	lipid catabolic process
JK088_05775	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JK088_05780	COG0626	cystathionine gamma-synthase activity
JK088_05790	COG0733	neurotransmitter:sodium symporter activity
JK088_05800	COG0564	pseudouridine synthase activity
JK088_05810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JK088_05815	COG1151	hydroxylamine reductase activity
JK088_05820	COG3604	Transcriptional regulator
JK088_05830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JK088_05835	COG4136	ATPase activity
JK088_05840	COG4135	transport system, permease component
JK088_05845	COG4134	Bacterial extracellular solute-binding protein
JK088_05850	COG0398	Pfam SNARE associated Golgi protein
JK088_05860	COG0493	'glutamate synthase
JK088_05885	COG3313	Fe-S protein
JK088_05910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JK088_05930	COG1061	Type III restriction enzyme res subunit
JK088_05935	COG1187	pseudouridine synthase activity
JK088_05940	COG2814	Major facilitator Superfamily
JK088_05970	COG3005	denitrification pathway
JK088_05975	COG0702	epimerase
JK088_05980	COG0534	Mate efflux family protein
JK088_05985	COG4181	ATPase activity
JK088_06000	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JK088_06015	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JK088_06020	COG2985	domain, Protein
JK088_06020	COG3273	potassium ion transport
JK088_06025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JK088_06035	COG1737	Transcriptional regulator
JK088_06040	COG0076	glutamate decarboxylase activity
JK088_06050	COG2431	L-lysine efflux transmembrane transporter activity
JK088_06060	COG3070	regulator of competence-specific genes
JK088_06075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JK088_06075	COG4191	Histidine kinase
JK088_06085	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JK088_06090	COG3048	D-serine ammonia-lyase activity
JK088_06095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JK088_06100	COG4988	ABC transporter
JK088_06105	COG0492	ferredoxin-NADP+ reductase activity
JK088_06130	COG0471	metal ion transport
JK088_06135	COG2949	membrane
JK088_06140	COG0281	malic enzyme
JK088_06145	COG1643	Atp-dependent helicase
JK088_06150	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
JK088_06165	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JK088_06200	COG0247	lactate metabolic process
JK088_06200	COG0277	FAD linked oxidase domain protein
JK088_06215	COG2986	histidine ammonia-lyase
JK088_06220	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JK088_06225	COG0010	Belongs to the arginase family
JK088_06230	COG1228	amidohydrolase
JK088_06235	COG2188	Transcriptional regulator
JK088_06250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JK088_06260	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JK088_06270	COG0393	Putative heavy-metal-binding
JK088_06300	COG3706	GGDEF domain
JK088_06305	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JK088_06310	COG0072	phenylalanine-tRNA ligase activity
JK088_06310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JK088_06320	COG0776	regulation of translation
JK088_06330	COG0500	methyltransferase
JK088_06335	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JK088_06340	COG0295	cytidine deaminase activity
JK088_06345	COG1346	cytolysis
JK088_06350	COG1380	Effector of murein hydrolase LrgA
JK088_06355	COG2925	Exonuclease
JK088_06360	COG1823	symporter activity
JK088_06365	COG0702	epimerase
JK088_06370	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JK088_06375	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JK088_06395	COG2988	succinylglutamate desuccinylase activity
JK088_06400	COG4139	cobalamin transport
JK088_06405	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
JK088_06425	COG0583	DNA-binding transcription factor activity
JK088_06445	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JK088_06450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JK088_06455	COG3475	LICD family
JK088_06460	COG1451	nucleotide metabolic process
JK088_06465	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
JK088_06495	COG3938	Belongs to the proline racemase family
JK088_06510	COG2423	ornithine cyclodeaminase activity
JK088_06515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JK088_06520	COG3842	ATPase activity
JK088_06525	COG1176	ABC-type spermidine putrescine transport system, permease component I
JK088_06530	COG1177	transmembrane transport
JK088_06540	COG3291	Pkd domain containing protein
JK088_06555	COG0444	Belongs to the ABC transporter superfamily
JK088_06560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JK088_06565	COG0601	transmembrane transport
JK088_06575	COG2195	Cleaves the N-terminal amino acid of tripeptides
JK088_06585	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JK088_06595	COG0625	glutathione transferase activity
JK088_06655	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JK088_06660	COG0583	DNA-binding transcription factor activity
JK088_06700	COG4191	Histidine kinase
JK088_06700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JK088_06710	COG3300	MHYT domain
JK088_06710	COG5001	Diguanylate cyclase
JK088_06720	COG1280	lysine exporter protein (LysE YggA)
JK088_06725	COG1328	CTP reductase activity
JK088_06730	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JK088_06740	COG0861	Integral membrane protein TerC family
JK088_06745	COG0739	heme binding
JK088_06785	COG3501	Rhs element vgr protein
JK088_06810	COG0515	serine threonine protein kinase
JK088_06845	COG1522	sequence-specific DNA binding
JK088_06930	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JK088_06940	COG0814	amino acid
JK088_06960	COG1132	(ABC) transporter
JK088_06965	COG1132	(ABC) transporter
JK088_06990	COG0443	Heat shock 70 kDa protein
JK088_06995	COG0443	Heat shock 70 kDa protein
JK088_07035	COG0243	molybdopterin cofactor binding
JK088_07040	COG0437	4 iron, 4 sulfur cluster binding
JK088_07045	COG3302	dmso reductase anchor subunit
JK088_07050	COG3381	protein complex oligomerization
JK088_07060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JK088_07065	COG1643	Atp-dependent helicase
JK088_07080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JK088_07090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JK088_07095	COG1215	transferase activity, transferring glycosyl groups
JK088_07100	COG0438	transferase activity, transferring glycosyl groups
JK088_07140	COG2204	response regulator
JK088_07170	COG1793	dna ligase
JK088_07180	COG0534	Mate efflux family protein
JK088_07185	COG0307	riboflavin synthase, alpha
JK088_07195	COG3001	Fructosamine kinase
JK088_07200	COG2201	protein-glutamate methylesterase activity
JK088_07205	COG3706	GGDEF domain
JK088_07215	COG0791	NLP P60 protein
JK088_07220	COG3290	protein histidine kinase activity
JK088_07220	COG0840	transmembrane signaling receptor activity
JK088_07255	COG3148	PFAM DTW domain containing protein
JK088_07260	COG1940	carbohydrate kinase activity
JK088_07275	COG0746	molybdenum cofactor guanylyltransferase activity
JK088_07280	COG3842	ATPase activity
JK088_07295	COG2204	response regulator
JK088_07300	COG4191	Histidine kinase
JK088_07305	COG0488	(ABC) transporter
JK088_07310	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JK088_07330	COG3381	protein complex oligomerization
JK088_07340	COG0243	molybdopterin cofactor binding
JK088_07340	COG3383	formate dehydrogenase (NAD+) activity
JK088_07345	COG0437	4 iron, 4 sulfur cluster binding
JK088_07370	COG0004	ammonium transporteR
JK088_07380	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JK088_07385	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JK088_07395	COG1177	transmembrane transport
JK088_07405	COG3842	ATPase activity
JK088_07425	COG0037	tRNA processing
JK088_07430	COG0589	response to stress
JK088_07435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JK088_07450	COG2217	Heavy metal translocating P-type atpase
JK088_07460	COG2010	Cytochrome c
JK088_07475	COG3278	Belongs to the heme-copper respiratory oxidase family
JK088_07490	COG2205	protein histidine kinase activity
JK088_07490	COG0784	Response regulator, receiver
JK088_07575	COG3120	sequence-specific DNA binding
JK088_07580	COG1067	ATP-dependent peptidase activity
JK088_07585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JK088_07600	COG0488	(ABC) transporter
JK088_07610	COG0116	Belongs to the methyltransferase superfamily
JK088_07610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JK088_07620	COG0167	dihydroorotate dehydrogenase activity
JK088_07625	COG2902	Dehydrogenase
JK088_07635	COG0308	aminopeptidase N
JK088_07650	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JK088_07655	COG1956	GAF domain-containing protein
JK088_07660	COG1132	(ABC) transporter
JK088_07665	COG2995	paraquat-inducible protein a
JK088_07670	COG3008	intermembrane lipid transfer
JK088_07675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JK088_07675	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JK088_07695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JK088_07700	COG1666	GTP binding
JK088_07710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JK088_07715	COG4597	amino acid ABC transporter
JK088_07720	COG0765	amino acid transport
JK088_07725	COG1126	abc transporter atp-binding protein
JK088_07730	COG0670	Belongs to the BI1 family
JK088_07740	COG2920	part of a sulfur-relay system
JK088_07745	COG1254	Belongs to the acylphosphatase family
JK088_07750	COG0840	transmembrane signaling receptor activity
JK088_07755	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JK088_07795	COG3706	GGDEF domain
JK088_07800	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JK088_07805	COG0602	queuosine metabolic process
JK088_07810	COG0561	phosphatase activity
JK088_07835	COG2828	Protein conserved in bacteria
JK088_07845	COG0372	Belongs to the citrate synthase family
JK088_07850	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JK088_07880	COG0730	response to heat
JK088_07900	COG0457	Tetratricopeptide repeat
JK088_07970	COG4790	Type iii secretion
JK088_07975	COG4794	Type iii secretion
JK088_07980	COG4791	protein targeting
JK088_07985	COG4792	protein secretion
JK088_07995	COG1073	alpha beta
JK088_08000	COG1073	alpha beta
JK088_08030	COG3177	Filamentation induced by cAMP protein fic
JK088_08050	COG4669	(LipO)protein
JK088_08120	COG1012	belongs to the aldehyde dehydrogenase family
JK088_08125	COG3284	Transcriptional regulator
JK088_08140	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JK088_08145	COG0363	glucosamine-6-phosphate deaminase activity
JK088_08150	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JK088_08155	COG4565	transcriptional regulatory protein
JK088_08160	COG3290	protein histidine kinase activity
JK088_08175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK088_08190	COG1858	cytochrome C peroxidase
JK088_08195	COG0527	aspartate kinase activity
JK088_08200	COG0662	Cupin 2, conserved barrel domain protein
JK088_08205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JK088_08210	COG0456	acetyltransferase
JK088_08215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JK088_08230	COG4175	Glycine betaine
JK088_08235	COG4176	ABC-type proline glycine betaine transport system permease component
JK088_08240	COG2113	Glycine betaine
JK088_08260	COG1028	Short-chain dehydrogenase reductase Sdr
JK088_08270	COG0745	RESPONSE REGULATOR receiver
JK088_08275	COG0642	Histidine kinase
JK088_08280	COG1368	sulfuric ester hydrolase activity
JK088_08305	COG1115	amino acid carrier protein
JK088_08315	COG1280	lysine exporter protein (LysE YggA)
JK088_08320	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JK088_08430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
JK088_08440	COG1560	Kdo2-lipid A biosynthetic process
JK088_08445	COG0531	amino acid
JK088_08455	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JK088_08460	COG3063	Type IV pilus biogenesis stability protein PilW
JK088_08475	COG3437	response regulator, receiver
JK088_08475	COG4999	Histidine kinase
JK088_08475	COG2205	protein histidine kinase activity
JK088_08475	COG3850	Histidine kinase
JK088_08490	COG0110	maltose O-acetyltransferase activity
JK088_08510	COG2315	Protein conserved in bacteria
JK088_08515	COG1846	Transcriptional regulator
JK088_08530	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JK088_08540	COG2200	EAL domain
JK088_08540	COG2771	luxR family
JK088_08545	COG1227	inorganic diphosphatase activity
JK088_08550	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JK088_08555	COG1012	belongs to the aldehyde dehydrogenase family
JK088_08560	COG2957	Belongs to the agmatine deiminase family
JK088_08570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JK088_08575	COG1012	belongs to the aldehyde dehydrogenase family
JK088_08580	COG1917	Cupin 2, conserved barrel domain protein
JK088_08580	COG1396	sequence-specific DNA binding
JK088_08585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JK088_08590	COG0174	glutamine synthetase
JK088_08595	COG1757	Na H antiporter
JK088_08615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JK088_08620	COG1280	lysine exporter protein (LysE YggA)
JK088_08750	COG3668	Plasmid stabilization system
JK088_08755	COG4735	regulation of single-species biofilm formation
JK088_08815	COG1051	belongs to the nudix hydrolase family
JK088_08970	COG0346	lactoylglutathione lyase activity
JK088_09250	COG0456	acetyltransferase
JK088_09285	COG0494	nUDIX hydrolase
JK088_09290	COG0456	acetyltransferase
JK088_09445	COG1051	belongs to the nudix hydrolase family
JK088_09470	COG3668	Plasmid stabilization system
JK088_09480	COG0346	lactoylglutathione lyase activity
JK088_09670	COG0494	nUDIX hydrolase
JK088_09735	COG0456	acetyltransferase
JK088_09950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JK088_09960	COG3768	UPF0283 membrane protein
JK088_09965	COG3106	COG3106 Predicted ATPase
JK088_09980	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JK088_09985	COG2205	protein histidine kinase activity
JK088_09985	COG0784	Response regulator, receiver
JK088_10010	COG0814	amino acid
JK088_10015	COG1760	l-serine dehydratase
JK088_10020	COG2200	EAL domain
JK088_10030	COG0720	synthase
JK088_10035	COG0840	transmembrane signaling receptor activity
JK088_10040	COG0017	Asparaginyl-tRNA synthetase
JK088_10050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JK088_10065	COG1448	Aminotransferase
JK088_10085	COG0840	transmembrane signaling receptor activity
JK088_10090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JK088_10095	COG1846	Transcriptional regulator
JK088_10120	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JK088_10135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JK088_10140	COG3108	Peptidase M15
JK088_10145	COG2989	Protein conserved in bacteria
JK088_10170	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JK088_10180	COG3088	subunit of a heme lyase
JK088_10180	COG4235	cytochrome complex assembly
JK088_10190	COG1138	Cytochrome C-type biogenesis protein
JK088_10195	COG3301	Polysulphide reductase, NrfD
JK088_10200	COG0437	4 iron, 4 sulfur cluster binding
JK088_10210	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JK088_10230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JK088_10235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JK088_10240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JK088_10265	COG0019	diaminopimelate decarboxylase activity
JK088_10305	COG0322	excinuclease ABC activity
JK088_10310	COG2197	response regulator
JK088_10315	COG0417	DNA replication proofreading
JK088_10325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JK088_10330	COG3099	Belongs to the UPF0263 family
JK088_10335	COG1187	pseudouridine synthase activity
JK088_10345	COG0009	L-threonylcarbamoyladenylate synthase
JK088_10350	COG0613	PHP domain protein
JK088_10360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JK088_10365	COG0512	Glutamine amidotransferase of anthranilate synthase
JK088_10370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JK088_10375	COG0134	indole-3-glycerol-phosphate synthase activity
JK088_10375	COG0135	phosphoribosylanthranilate isomerase activity
JK088_10380	COG0133	tryptophan synthase activity
JK088_10385	COG0159	tryptophan synthase activity
JK088_10390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JK088_10395	COG0318	PFAM AMP-dependent synthetase and ligase
JK088_10400	COG1301	dicarboxylic acid transport
JK088_10420	COG2917	probably involved in intracellular septation
JK088_10430	COG2350	Protein conserved in bacteria
JK088_10440	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JK088_10445	COG0583	DNA-binding transcription factor activity
JK088_10460	COG3706	GGDEF domain
JK088_10460	COG4251	negative regulation of phosphorylation
JK088_10460	COG5001	Diguanylate cyclase
JK088_10460	COG2203	Gaf domain
JK088_10465	COG1032	radical SAM domain protein
JK088_10470	COG0840	transmembrane signaling receptor activity
JK088_10475	COG0745	RESPONSE REGULATOR receiver
JK088_10480	COG5002	protein histidine kinase activity
JK088_10480	COG3850	Histidine kinase
JK088_10530	COG1335	isochorismatase
JK088_10535	COG1136	(ABC) transporter
JK088_10535	COG0577	efflux transmembrane transporter activity
JK088_10540	COG0577	efflux transmembrane transporter activity
JK088_10540	COG1136	(ABC) transporter
JK088_10545	COG0577	efflux transmembrane transporter activity
JK088_10545	COG1136	(ABC) transporter
JK088_10555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK088_10570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JK088_10585	COG3118	belongs to the thioredoxin family
JK088_10590	COG4232	protein-disulfide reductase activity
JK088_10630	COG2863	cytochrome
JK088_10635	COG3258	Cytochrome c
JK088_10640	COG2995	paraquat-inducible protein a
JK088_10645	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JK088_10645	COG3008	intermembrane lipid transfer
JK088_10655	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JK088_10680	COG4166	transmembrane transport
JK088_10685	COG0284	orotidine-5'-phosphate decarboxylase activity
JK088_10690	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JK088_10695	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
JK088_10705	COG0539	negative regulation of cytoplasmic translation
JK088_10710	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JK088_10715	COG0616	signal peptide processing
JK088_10720	COG1028	Short-chain dehydrogenase reductase Sdr
JK088_10735	COG0587	DNA-directed DNA polymerase activity
JK088_10740	COG0784	Response regulator, receiver
JK088_10740	COG0835	chemotaxis
JK088_10745	COG1940	carbohydrate kinase activity
JK088_10750	COG0469	pyruvate kinase activity
JK088_10755	COG4667	esterase of the alpha-beta hydrolase superfamily
JK088_10770	COG0733	neurotransmitter:sodium symporter activity
JK088_10785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JK088_10785	COG1263	PTS System
JK088_10790	COG0084	hydrolase, TatD family'
JK088_10805	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JK088_10835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JK088_10840	COG0416	fatty acid biosynthetic process
JK088_10850	COG1399	metal-binding, possibly nucleic acid-binding protein
JK088_10855	COG0424	maF-like protein
JK088_10860	COG0564	pseudouridine synthase activity
JK088_10865	COG1530	ribonuclease E activity
JK088_10870	COG0659	secondary active sulfate transmembrane transporter activity
JK088_10875	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JK088_10880	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JK088_10890	COG0572	uridine kinase
JK088_10895	COG0489	protein tyrosine kinase activity
JK088_10900	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JK088_10900	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JK088_10910	COG2186	Transcriptional regulator
JK088_10915	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JK088_10920	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JK088_10925	COG3318	Belongs to the UPF0149 family
JK088_10925	COG3012	SEC-C Motif Domain Protein
JK088_10930	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JK088_10940	COG0366	Alpha amylase catalytic
JK088_10945	COG1122	ATPase activity
JK088_10950	COG4120	Belongs to the binding-protein-dependent transport system permease family
JK088_10960	COG3092	negative regulation of chromosome organization
JK088_10965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JK088_10970	COG0857	belongs to the CobB CobQ family
JK088_10970	COG0280	phosphate acetyltransferase
JK088_10975	COG3174	membrane
JK088_10985	COG0435	Glutathione S-transferase
JK088_10995	COG0444	Belongs to the ABC transporter superfamily
JK088_11000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JK088_11005	COG0601	transmembrane transport
JK088_11015	COG0314	molybdopterin synthase activity
JK088_11020	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JK088_11025	COG0315	cyclic pyranopterin monophosphate synthase activity
JK088_11030	COG0521	Mo-molybdopterin cofactor biosynthetic process
JK088_11035	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JK088_11040	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JK088_11045	COG2198	Histidine kinase
JK088_11050	COG2204	response regulator
JK088_11055	COG0556	nucleotide-excision repair
JK088_11065	COG4657	Part of a membrane complex involved in electron transport
JK088_11070	COG2878	Part of a membrane complex involved in electron transport
JK088_11075	COG4656	Part of a membrane complex involved in electron transport
JK088_11080	COG4658	electron transport chain
JK088_11085	COG4659	FMN binding
JK088_11090	COG4660	Part of a membrane complex involved in electron transport
JK088_11095	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JK088_11100	COG0346	lactoylglutathione lyase activity
JK088_11110	COG2885	chlorophyll binding
JK088_11115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JK088_11120	COG2056	Na+-H+ antiporter family
JK088_11130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JK088_11150	COG1012	belongs to the aldehyde dehydrogenase family
JK088_11150	COG1454	alcohol dehydrogenase
JK088_11155	COG2095	MarC family integral membrane protein
JK088_11160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JK088_11165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JK088_11170	COG1757	Na H antiporter
JK088_11185	COG3081	Nucleoid-associated protein
JK088_11190	COG3082	Protein of unknown function (DUF1414)
JK088_11195	COG3083	sulfuric ester hydrolase activity
JK088_11205	COG0582	viral genome integration into host DNA
JK088_11255	COG0123	including yeast histone deacetylase and acetoin utilization protein
JK088_11270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JK088_11275	COG0778	Nitroreductase
JK088_11280	COG0446	pyridine nucleotide-disulphide oxidoreductase
JK088_11280	COG1902	pentaerythritol trinitrate reductase activity
JK088_11285	COG0616	signal peptide processing
JK088_11290	COG0252	asparaginase activity
JK088_11295	COG3139	Protein of unknown function (DUF1315)
JK088_11305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JK088_11310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JK088_11325	COG2226	methyltransferase
JK088_11350	COG0346	lactoylglutathione lyase activity
JK088_11355	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JK088_11360	COG0668	transmembrane transport
JK088_11365	COG2983	Belongs to the UPF0260 family
JK088_11370	COG2261	transglycosylase associated protein
JK088_11385	COG3681	Belongs to the UPF0597 family
JK088_11390	COG0251	oxidation-reduction process
JK088_11400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JK088_11405	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JK088_11410	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JK088_11420	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JK088_11425	COG2832	Protein of unknown function (DUF454)
JK088_11430	COG0745	RESPONSE REGULATOR receiver
JK088_11435	COG0583	DNA-binding transcription factor activity
JK088_11440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JK088_11445	COG1286	toxin biosynthetic process
JK088_11450	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
JK088_11455	COG0285	dihydrofolate synthase activity
JK088_11460	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JK088_11465	COG0101	tRNA pseudouridine synthase activity
JK088_11475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JK088_11480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JK088_11485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JK088_11490	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JK088_11490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JK088_11495	COG0431	NADPH-dependent FMN reductase
JK088_11505	COG3101	peptidyl-lysine hydroxylation
JK088_11510	COG2860	membrane
JK088_11515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JK088_11520	COG2890	protein-(glutamine-N5) methyltransferase activity
JK088_11525	COG2840	Smr protein MutS2
JK088_11530	COG2062	phosphohistidine phosphatase, SixA
JK088_11545	COG1024	Enoyl-CoA hydratase
JK088_11545	COG1250	3-hydroxyacyl-CoA dehydrogenase
JK088_11550	COG0183	Belongs to the thiolase family
JK088_11565	COG2067	long-chain fatty acid transport protein
JK088_11570	COG2067	long-chain fatty acid transport protein
JK088_11575	COG2853	Lipoprotein
JK088_11590	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JK088_11595	COG1138	Cytochrome C-type biogenesis protein
JK088_11600	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JK088_11605	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JK088_11610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JK088_11615	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JK088_11620	COG4133	protoheme IX ABC transporter activity
JK088_11630	COG0835	chemotaxis
JK088_11640	COG1192	Involved in chromosome partitioning
JK088_11645	COG2201	protein-glutamate methylesterase activity
JK088_11650	COG2198	Histidine kinase
JK088_11650	COG0643	Histidine kinase
JK088_11650	COG0784	Response regulator, receiver
JK088_11655	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JK088_11695	COG1987	bacterial-type flagellum assembly
JK088_11745	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JK088_11755	COG1677	Flagellar hook-basal body complex protein FliE
JK088_11775	COG1516	flagellar protein fliS
JK088_11785	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JK088_11790	COG1334	flagellar protein FlaG
JK088_11795	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JK088_11800	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JK088_11805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JK088_11810	COG2837	iron assimilation
JK088_11835	COG1393	Belongs to the ArsC family
JK088_11840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JK088_11855	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JK088_11860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JK088_11865	COG2716	regulation of RNA biosynthetic process
JK088_11870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JK088_11885	COG4783	chaperone-mediated protein folding
JK088_11890	COG1393	Belongs to the ArsC family
JK088_11910	COG2233	PERMEase
JK088_11915	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JK088_11920	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JK088_11925	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JK088_11930	COG0121	glutamine amidotransferase
JK088_11935	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JK088_11940	COG1960	acyl-CoA dehydrogenase activity
JK088_11955	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JK088_11960	COG0328	RNA-DNA hybrid ribonuclease activity
JK088_11965	COG2226	methyltransferase
JK088_11970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JK088_11975	COG0741	lytic transglycosylase activity
JK088_11975	COG1388	LysM domain
JK088_11985	COG3021	interspecies interaction between organisms
JK088_11990	COG0347	Belongs to the P(II) protein family
JK088_12000	COG0037	tRNA processing
JK088_12005	COG0825	malonyl-CoA metabolic process
JK088_12010	COG0587	DNA-directed DNA polymerase activity
JK088_12015	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JK088_12020	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JK088_12025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JK088_12030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JK088_12035	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JK088_12040	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
JK088_12050	COG0750	zinc metalloprotease
JK088_12055	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JK088_12060	COG0575	Belongs to the CDS family
JK088_12065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JK088_12070	COG0233	cytoplasmic translational termination
JK088_12075	COG0528	UMP kinase activity
JK088_12080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JK088_12085	COG0052	Belongs to the universal ribosomal protein uS2 family
JK088_12090	COG0024	Methionine aminopeptidase
JK088_12095	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JK088_12105	COG0564	pseudouridine synthase activity
JK088_12110	COG3098	single-species biofilm formation
JK088_12135	COG1671	Belongs to the UPF0178 family
JK088_12140	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JK088_12150	COG0254	rRNA binding
JK088_12155	COG1720	tRNA m6t6A37 methyltransferase activity
JK088_12160	COG0442	prolyl-tRNA aminoacylation
JK088_12180	COG0733	neurotransmitter:sodium symporter activity
JK088_12195	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JK088_12200	COG0514	ATP-dependent DNA helicase (RecQ)
JK088_12205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JK088_12220	COG1477	protein flavinylation
JK088_12225	COG2871	sodium ion transport
JK088_12230	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JK088_12235	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JK088_12240	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JK088_12245	COG1805	sodium ion transport
JK088_12250	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JK088_12255	COG0271	Belongs to the BolA IbaG family
JK088_12260	COG2813	Specifically methylates the guanine in position
JK088_12265	COG3056	Lipoprotein
JK088_12285	COG1595	DNA-templated transcription, initiation
JK088_12305	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JK088_12310	COG0693	protein deglycase activity
JK088_12315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JK088_12320	COG3706	GGDEF domain
JK088_12325	COG2166	iron-sulfur cluster assembly
JK088_12330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JK088_12335	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JK088_12345	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JK088_12345	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JK088_12355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JK088_12360	COG1074	ATP-dependent DNA helicase activity
JK088_12365	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JK088_12385	COG3141	response to X-ray
JK088_12390	COG2171	N-acyltransferase activity
JK088_12395	COG0584	glycerophosphoryl diester phosphodiesterase
JK088_12400	COG2271	Major facilitator Superfamily
JK088_12405	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JK088_12410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JK088_12415	COG1349	DNA-binding transcription factor activity
JK088_12420	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JK088_12425	COG0598	Magnesium transport protein CorA
JK088_12445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JK088_12450	COG1609	Transcriptional regulator
JK088_12455	COG2211	Major facilitator Superfamily
JK088_12470	COG2017	converts alpha-aldose to the beta-anomer
JK088_12475	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JK088_12480	COG1085	galactose-1-phosphate uridylyltransferase
JK088_12485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JK088_12490	COG1609	Transcriptional regulator
JK088_12495	COG3250	beta-galactosidase activity
JK088_12505	COG0531	amino acid
JK088_12510	COG0583	DNA-binding transcription factor activity
JK088_12570	COG4964	Belongs to the GSP D family
JK088_12595	COG2169	Transcriptional regulator
JK088_12600	COG1022	Amp-dependent synthetase and ligase
JK088_12610	COG0583	DNA-binding transcription factor activity
JK088_12615	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JK088_12620	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JK088_12630	COG0560	Phosphoserine phosphatase
JK088_12640	COG0813	purine-nucleoside phosphorylase activity
JK088_12645	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JK088_12650	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JK088_12655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JK088_12660	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JK088_12665	COG0084	hydrolase, TatD family'
JK088_12675	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JK088_12695	COG3153	acetyltransferase
JK088_12700	COG3154	lipid carrier protein
JK088_12710	COG0826	peptidase U32
JK088_12715	COG0826	peptidase U32
JK088_12720	COG0534	Mate efflux family protein
JK088_12735	COG1185	polyribonucleotide nucleotidyltransferase activity
JK088_12740	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JK088_12745	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JK088_12750	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JK088_12755	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JK088_12760	COG0195	Participates in both transcription termination and antitermination
JK088_12765	COG0779	Required for maturation of 30S ribosomal subunits
JK088_12780	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JK088_12785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JK088_12790	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JK088_12795	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JK088_12800	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JK088_12805	COG1534	Rna-binding protein
JK088_12810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JK088_12815	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JK088_12820	COG2027	D-alanyl-D-alanine carboxypeptidase
JK088_12830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JK088_12835	COG0739	heme binding
JK088_12840	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JK088_12850	COG0316	Belongs to the HesB IscA family
JK088_12855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JK088_12860	COG0628	permease
JK088_12865	COG2813	Specifically methylates the guanine in position
JK088_12870	COG0784	Response regulator, receiver
JK088_12870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JK088_12870	COG2198	Histidine kinase
JK088_12870	COG2205	protein histidine kinase activity
JK088_12875	COG0747	negative chemotaxis
JK088_12885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JK088_12890	COG0444	Belongs to the ABC transporter superfamily
JK088_12895	COG4608	Belongs to the ABC transporter superfamily
JK088_12905	COG2971	BadF BadG BcrA BcrD
JK088_12920	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JK088_12925	COG3842	ATPase activity
JK088_12935	COG1840	ABC-type Fe3 transport system, periplasmic component
JK088_12940	COG0004	ammonium transporteR
JK088_12950	COG3112	Uncharacterised protein family (UPF0231)
JK088_12955	COG1049	propionate catabolic process, 2-methylcitrate cycle
JK088_12960	COG1752	Esterase of the alpha-beta hydrolase superfamily
JK088_12965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JK088_12970	COG1643	Atp-dependent helicase
JK088_12975	COG1489	DNA binding
JK088_12985	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JK088_12995	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JK088_13000	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JK088_13005	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JK088_13010	COG1560	Kdo2-lipid A biosynthetic process
JK088_13015	COG0842	Transport permease protein
JK088_13020	COG1131	(ABC) transporter
JK088_13025	COG0659	secondary active sulfate transmembrane transporter activity
JK088_13030	COG0288	reversible hydration of carbon dioxide
JK088_13045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JK088_13050	COG0508	dehydrogenase complex catalyzes the overall conversion of
JK088_13055	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JK088_13060	COG2186	Transcriptional regulator
JK088_13070	COG0157	Belongs to the NadC ModD family
JK088_13080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JK088_13085	COG1459	type II secretion system
JK088_13095	COG0237	dephospho-CoA kinase activity
JK088_13100	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
JK088_13105	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JK088_13110	COG0335	large ribosomal subunit rRNA binding
JK088_13115	COG0336	Belongs to the RNA methyltransferase TrmD family
JK088_13120	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JK088_13125	COG0228	four-way junction DNA binding
JK088_13130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JK088_13135	COG4137	Cytochrome C assembly protein
JK088_13140	COG4536	flavin adenine dinucleotide binding
JK088_13145	COG1854	S-ribosylhomocysteine lyase activity
JK088_13155	COG2918	glutathione biosynthetic process
JK088_13160	COG0612	Peptidase, M16
JK088_13165	COG1238	metal cluster binding
JK088_13175	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JK088_13180	COG0511	ligase activity, forming carbon-carbon bonds
JK088_13180	COG5016	pyruvate
JK088_13185	COG3630	sodium ion export across plasma membrane
JK088_13245	COG0527	aspartate kinase activity
JK088_13250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JK088_13255	COG2137	regulation of response to DNA damage stimulus
JK088_13280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JK088_13285	COG1061	Type III restriction enzyme res subunit
JK088_13290	COG1002	Type II restriction enzyme, methylase subunits
JK088_13320	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JK088_13330	COG1546	Belongs to the CinA family
JK088_13355	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JK088_13425	COG0582	viral genome integration into host DNA
JK088_13430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JK088_13435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JK088_13445	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JK088_13450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JK088_13455	COG0585	pseudouridine synthase activity
JK088_13460	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JK088_13465	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JK088_13470	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JK088_13475	COG0148	phosphopyruvate hydratase activity
JK088_13480	COG0504	CTP synthase activity
JK088_13485	COG3956	TIGRFAM MazG family protein
JK088_13490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JK088_13495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JK088_13505	COG0736	holo-[acyl-carrier-protein] synthase activity
JK088_13510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JK088_13515	COG1381	Involved in DNA repair and RecF pathway recombination
JK088_13520	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JK088_13525	COG0571	ribonuclease III activity
JK088_13535	COG0481	GTPase activity
JK088_13540	COG3086	response to oxidative stress
JK088_13550	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
JK088_13555	COG1595	DNA-templated transcription, initiation
JK088_13560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JK088_13565	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JK088_13570	COG0354	folic acid binding
JK088_13585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JK088_13590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JK088_13595	COG3079	Belongs to the UPF0149 family
JK088_13600	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JK088_13610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JK088_13615	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JK088_13620	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JK088_13630	COG0583	DNA-binding transcription factor activity
JK088_13645	COG0668	transmembrane transport
JK088_13650	COG0191	fructose-bisphosphate aldolase activity
JK088_13655	COG0126	phosphoglycerate kinase activity
JK088_13660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JK088_13665	COG4771	TonB-dependent receptor
JK088_13670	COG0583	DNA-binding transcription factor activity
JK088_13675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JK088_13680	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JK088_13690	COG3091	SprT-like family
JK088_13695	COG2356	endonuclease I
JK088_13700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JK088_13705	COG0189	ligase activity
JK088_13710	COG1678	Uncharacterized ACR, COG1678
JK088_13715	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JK088_13730	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JK088_13735	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JK088_13740	COG0762	integral membrane protein
JK088_13745	COG1872	DUF167
JK088_13755	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JK088_13760	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JK088_13765	COG2066	Belongs to the glutaminase family
JK088_13775	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JK088_13785	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JK088_13790	COG0741	lytic transglycosylase activity
JK088_13860	COG1012	belongs to the aldehyde dehydrogenase family
JK088_13900	COG3437	response regulator, receiver
JK088_13910	COG3394	polysaccharide catabolic process
JK088_13915	COG1486	melibiose metabolic process
JK088_13920	COG1447	Phosphotransferase system cellobiose-specific component IIA
JK088_13925	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JK088_13930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JK088_13935	COG0726	polysaccharide deacetylase
JK088_13945	COG1028	Short-chain dehydrogenase reductase Sdr
JK088_13960	COG0795	lipopolysaccharide-transporting ATPase activity
JK088_13965	COG0795	lipopolysaccharide-transporting ATPase activity
JK088_13970	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JK088_13975	COG2927	DNA polymerase III (CHI subunit)
JK088_13980	COG0525	valine-tRNA ligase activity
JK088_14005	COG2235	arginine
JK088_14010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JK088_14020	COG0540	Belongs to the ATCase OTCase family
JK088_14025	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
JK088_14030	COG0251	oxidation-reduction process
JK088_14035	COG0204	Acyl-transferase
JK088_14040	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JK088_14045	COG5007	Belongs to the BolA IbaG family
JK088_14055	COG2854	intermembrane phospholipid transfer
JK088_14060	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JK088_14065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JK088_14070	COG1127	ABC transporter
JK088_14080	COG0517	IMP dehydrogenase activity
JK088_14080	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JK088_14090	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JK088_14095	COG1137	ATPase activity
JK088_14105	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JK088_14110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JK088_14115	COG1660	Displays ATPase and GTPase activities
JK088_14120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JK088_14125	COG2239	Acts as a magnesium transporter
JK088_14130	COG0312	modulator of DNA gyrase
JK088_14135	COG3028	Belongs to the UPF0307 family
JK088_14140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JK088_14145	COG0564	pseudouridine synthase activity
JK088_14155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JK088_14160	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JK088_14165	COG0312	modulator of DNA gyrase
JK088_14175	COG3164	Protein of unknown function
JK088_14185	COG0424	maF-like protein
JK088_14190	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JK088_14195	COG1792	Involved in formation and maintenance of cell shape
JK088_14200	COG1077	Cell shape determining protein MreB Mrl
JK088_14235	COG2165	general secretion pathway protein
JK088_14245	COG1459	type II secretion system
JK088_14250	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JK088_14260	COG3409	Peptidoglycan-binding domain 1 protein
JK088_14260	COG3267	Type II secretory pathway component ExeA
JK088_14285	COG2200	EAL domain
JK088_14285	COG2199	diguanylate cyclase activity
JK088_14290	COG0629	single-stranded DNA binding
JK088_14305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JK088_14315	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JK088_14320	COG0527	aspartate kinase activity
JK088_14325	COG0646	methionine synthase
JK088_14325	COG1410	methionine synthase
JK088_14340	COG3335	DDE superfamily endonuclease
JK088_14380	COG0175	sulfate reduction
JK088_14385	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JK088_14390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JK088_14410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JK088_14415	COG0735	belongs to the Fur family
JK088_14425	COG0166	Belongs to the GPI family
JK088_14430	COG0432	Pfam Uncharacterised protein family UPF0047
JK088_14440	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JK088_14455	COG0359	binds to the 23S rRNA
JK088_14465	COG2965	DNA replication, synthesis of RNA primer
JK088_14470	COG0360	Binds together with S18 to 16S ribosomal RNA
JK088_14475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JK088_14480	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JK088_14490	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JK088_14495	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JK088_14525	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JK088_14535	COG0678	peroxiredoxin activity
JK088_14535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JK088_14545	COG0165	Argininosuccinate lyase
JK088_14545	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JK088_14550	COG0137	argininosuccinate synthase activity
JK088_14555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JK088_14560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JK088_14565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JK088_14570	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JK088_14580	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JK088_14585	COG0527	aspartate kinase activity
JK088_14585	COG0460	homoserine dehydrogenase
JK088_14590	COG0626	cystathionine gamma-synthase activity
JK088_14600	COG0281	malic enzyme
JK088_14610	COG2906	2 iron, 2 sulfur cluster binding
JK088_14615	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JK088_14620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JK088_14625	COG0049	tRNA binding
JK088_14635	COG2168	tRNA wobble position uridine thiolation
JK088_14640	COG2923	Belongs to the DsrF TusC family
JK088_14645	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JK088_14650	COG2964	Protein conserved in bacteria
JK088_14655	COG0545	Peptidyl-prolyl cis-trans isomerase
JK088_14665	COG2900	Belongs to the SlyX family
JK088_14670	COG1446	asparaginase
JK088_14675	COG1047	Peptidyl-prolyl cis-trans
JK088_14690	COG2249	NAD(P)H dehydrogenase (quinone) activity
JK088_14695	COG0488	(ABC) transporter
JK088_14705	COG0429	hydrolase of the alpha beta-hydrolase fold
JK088_14710	COG3089	Belongs to the UPF0270 family
JK088_14715	COG3954	Phosphoribulokinase
JK088_14720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JK088_14730	COG1012	belongs to the aldehyde dehydrogenase family
JK088_14740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JK088_14745	COG0512	Glutamine amidotransferase of anthranilate synthase
JK088_14760	COG0180	Tryptophanyl-tRNA synthetase
JK088_14765	COG0546	phosphoglycolate phosphatase activity
JK088_14770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JK088_14775	COG0557	exoribonuclease II activity
JK088_14780	COG1959	2 iron, 2 sulfur cluster binding
JK088_14785	COG1017	nitric oxide dioxygenase activity
JK088_14785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JK088_14790	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
JK088_14795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JK088_14800	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
JK088_14805	COG0330	HflC and HflK could
JK088_14810	COG0330	HflC and HflK could
JK088_14815	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JK088_14825	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JK088_14830	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JK088_14840	COG0802	atpase or kinase
JK088_14845	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JK088_14925	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JK088_14930	COG1162	GTPase activity
JK088_14935	COG0688	phosphatidylethanolamine metabolic process
JK088_14940	COG0471	metal ion transport
JK088_14985	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JK088_14990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JK088_14995	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JK088_15000	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JK088_15005	COG1045	serine acetyltransferase
JK088_15010	COG4942	peptidase
JK088_15030	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JK088_15035	COG1053	succinate dehydrogenase
JK088_15040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JK088_15045	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JK088_15050	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JK088_15060	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JK088_15065	COG1509	lysine 2,3-aminomutase activity
JK088_15070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JK088_15085	COG0459	protein refolding
JK088_15095	COG0534	Mate efflux family protein
JK088_15100	COG0205	6-phosphofructokinase activity
JK088_15110	COG3678	ATP-independent chaperone mediated protein folding
JK088_15115	COG0745	RESPONSE REGULATOR receiver
JK088_15120	COG2205	protein histidine kinase activity
JK088_15130	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JK088_15135	COG3030	protein affecting phage T7 exclusion by the F plasmid
JK088_15140	COG1027	Aspartate ammonia-lyase
JK088_15145	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JK088_15150	COG4232	protein-disulfide reductase activity
JK088_15160	COG3263	regulation of cellular component size
JK088_15170	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JK088_15190	COG2205	protein histidine kinase activity
JK088_15190	COG0784	Response regulator, receiver
JK088_15190	COG2198	Histidine kinase
JK088_15195	COG2814	Major facilitator Superfamily
JK088_15210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JK088_15215	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JK088_15220	COG0511	ligase activity, forming carbon-carbon bonds
JK088_15225	COG0439	Biotin carboxylase
JK088_15230	COG2264	protein methyltransferase activity
JK088_15235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JK088_15240	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JK088_15245	COG2814	Major facilitator Superfamily
JK088_15250	COG0488	(ABC) transporter
JK088_15255	COG3706	GGDEF domain
JK088_15315	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JK088_15325	COG4206	TonB-dependent receptor
JK088_15330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JK088_15345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JK088_15350	COG0534	Mate efflux family protein
JK088_15355	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JK088_15360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JK088_15365	COG2937	Belongs to the GPAT DAPAT family
JK088_15370	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JK088_15375	COG3161	chorismate lyase activity
JK088_15380	COG1580	Controls the rotational direction of flagella during chemotaxis
JK088_15385	COG0705	Rhomboid family
JK088_15390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JK088_15400	COG2177	Part of the ABC transporter FtsEX involved in
JK088_15405	COG2884	Cell division ATP-binding protein ftsE
JK088_15410	COG0552	protein localization to endoplasmic reticulum
JK088_15415	COG0742	ribosomal rna small subunit methyltransferase
JK088_15425	COG2095	MarC family integral membrane protein
JK088_15475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JK088_15480	COG0640	Transcriptional regulator
JK088_15485	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JK088_15490	COG1280	lysine exporter protein (LysE YggA)
JK088_15495	COG2267	carboxylic ester hydrolase activity
JK088_15500	COG0561	phosphatase activity
JK088_15515	COG3148	PFAM DTW domain containing protein
JK088_15520	COG2199	diguanylate cyclase activity
JK088_15520	COG2200	EAL domain
JK088_15520	COG3287	FIST C domain
JK088_15525	COG1011	Hydrolase
JK088_15530	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JK088_15540	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JK088_15545	COG0019	diaminopimelate decarboxylase activity
JK088_15555	COG1965	Belongs to the frataxin family
JK088_15560	COG3072	Adenylate cyclase
JK088_15565	COG0181	hydroxymethylbilane synthase activity
JK088_15570	COG1587	Uroporphyrinogen-III synthase
JK088_15575	COG2959	enzyme of heme biosynthesis
JK088_15580	COG3071	HemY protein
JK088_15620	COG0633	Ferredoxin
JK088_15625	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JK088_15640	COG3118	belongs to the thioredoxin family
JK088_15645	COG0513	Belongs to the DEAD box helicase family
JK088_15650	COG0248	Ppx GppA phosphatase
JK088_15655	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JK088_15665	COG0514	ATP-dependent DNA helicase (RecQ)
JK088_15670	COG2962	Rard protein
JK088_15680	COG1280	lysine exporter protein (LysE YggA)
JK088_15685	COG0405	Gamma-glutamyltransferase
JK088_15690	COG0210	DNA helicase
JK088_15700	COG3220	belongs to the UPF0276 family
JK088_15730	COG0006	proline dipeptidase activity
JK088_15740	COG2022	thiamine diphosphate biosynthetic process
JK088_15745	COG2104	thiamine diphosphate biosynthetic process
JK088_15750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JK088_15755	COG0352	thiamine-phosphate diphosphorylase activity
JK088_15760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JK088_15765	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JK088_15780	COG3335	DDE superfamily endonuclease
JK088_15820	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JK088_15830	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JK088_15835	COG0408	coproporphyrinogen oxidase activity
JK088_15840	COG0009	L-threonylcarbamoyladenylate synthase
JK088_15845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JK088_15850	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JK088_15855	COG0551	DNA topoisomerase type I activity
JK088_15860	COG2922	Belongs to the Smg family
JK088_15865	COG0758	DNA mediated transformation
JK088_15875	COG0242	peptide deformylase activity
JK088_15880	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JK088_15885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JK088_15885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JK088_15890	COG0569	domain protein
JK088_15895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JK088_15905	COG1272	protein, Hemolysin III
JK088_15910	COG4326	sporulation control protein
JK088_15920	COG3084	Protein conserved in bacteria
JK088_15930	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JK088_15935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JK088_15940	COG0204	Acyl-transferase
JK088_15950	COG0606	chelatase, subunit chli
JK088_15960	COG3978	acetolactate synthase activity
JK088_15965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JK088_15970	COG0129	dihydroxy-acid dehydratase activity
JK088_15980	COG0583	DNA-binding transcription factor activity
JK088_15985	COG2814	Major facilitator Superfamily
JK088_15990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JK088_15995	COG0765	amino acid transport
JK088_16000	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JK088_16005	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JK088_16010	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JK088_16015	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JK088_16020	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JK088_16025	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JK088_16040	COG0356	it plays a direct role in the translocation of protons across the membrane
JK088_16045	COG3312	ion transport
JK088_16050	COG1475	DNA binding
JK088_16055	COG1192	Involved in chromosome partitioning
JK088_16060	COG0357	Ribosomal RNA small subunit methyltransferase G
JK088_16065	COG0445	tRNA wobble uridine modification
JK088_16070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JK088_16075	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JK088_16080	COG0706	membrane insertase activity
JK088_16090	COG0594	ribonuclease P activity
JK088_16100	COG1126	abc transporter atp-binding protein
JK088_16115	COG0753	catalase activity
JK088_16125	COG1335	isochorismatase
JK088_16135	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JK088_16160	COG0583	DNA-binding transcription factor activity
JK088_16175	COG3713	MltA-interacting MipA family protein
JK088_16180	COG3015	lipoprotein NlpE involved in copper resistance
JK088_16185	COG1342	Belongs to the UPF0251 family
JK088_16215	COG4948	Mandelate Racemase Muconate Lactonizing
JK088_16225	COG0583	DNA-binding transcription factor activity
JK088_16260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JK088_16295	COG3842	ATPase activity
JK088_16325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JK088_16345	COG3706	GGDEF domain
JK088_16365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK088_16385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JK088_16400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JK088_16400	COG0574	Belongs to the PEP-utilizing enzyme family
JK088_16405	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JK088_16410	COG0252	asparaginase activity
JK088_16415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JK088_16420	COG0583	DNA-binding transcription factor activity
JK088_16435	COG3122	Protein conserved in bacteria
JK088_16445	COG1028	Short-chain dehydrogenase reductase Sdr
JK088_16455	COG1063	alcohol dehydrogenase
JK088_16460	COG1902	pentaerythritol trinitrate reductase activity
JK088_16475	COG0583	DNA-binding transcription factor activity
JK088_16485	COG0513	Belongs to the DEAD box helicase family
JK088_16525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JK088_16530	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JK088_16530	COG2207	Transcriptional regulator
JK088_16560	COG2354	Protein conserved in bacteria
JK088_16565	COG0418	dihydroorotase activity
JK088_16570	COG0401	homolog of Blt101
JK088_16575	COG3217	Mosc domain protein beta barrel domain protein
JK088_16575	COG0633	Ferredoxin
JK088_16575	COG0633	Ferredoxin
JK088_16575	COG3217	Mosc domain protein beta barrel domain protein
JK088_16580	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JK088_16585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JK088_16625	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JK088_16630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JK088_16640	COG0848	biopolymer transport protein
JK088_16645	COG0811	peptide transport
JK088_16650	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JK088_16660	COG3721	Heme iron utilization protein
JK088_16665	COG0748	coenzyme F420 binding
JK088_16675	COG0784	Response regulator, receiver
JK088_16675	COG0835	chemotaxis
JK088_16680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JK088_16690	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JK088_16690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JK088_16715	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JK088_16720	COG0783	Belongs to the Dps family
JK088_16725	COG0583	DNA-binding transcription factor activity
JK088_16740	COG4934	collagen metabolic process
JK088_16750	COG0366	Alpha amylase catalytic
JK088_16770	COG2249	NAD(P)H dehydrogenase (quinone) activity
JK088_16775	COG0589	response to stress
JK088_16780	COG0488	(ABC) transporter
JK088_16785	COG1505	serine-type exopeptidase activity
JK088_16795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK088_16805	COG2067	long-chain fatty acid transport protein
JK088_16815	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JK088_16845	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JK088_16865	COG3383	formate dehydrogenase (NAD+) activity
JK088_16880	COG0842	Transport permease protein
JK088_16885	COG1131	(ABC) transporter
JK088_16900	COG2706	6-phosphogluconolactonase activity
JK088_16910	COG1881	PFAM PEBP family protein
JK088_16920	COG0798	PFAM Bile acid sodium symporter
JK088_16935	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JK088_16940	COG2213	PTS system mannitol-specific
JK088_16945	COG1063	alcohol dehydrogenase
JK088_16955	COG1072	(Pantothenic acid kinase))
JK088_16960	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JK088_16980	COG0814	amino acid
JK088_16995	COG3314	Sporulation integral membrane protein YlbJ
JK088_17015	COG0739	heme binding
JK088_17020	COG5001	Diguanylate cyclase
JK088_17025	COG0583	DNA-binding transcription factor activity
JK088_17030	COG2814	Major facilitator Superfamily
JK088_17045	COG0697	spore germination
JK088_17050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JK088_17075	COG2207	Transcriptional regulator
JK088_17080	COG1280	lysine exporter protein (LysE YggA)
JK088_17090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JK088_17095	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JK088_17105	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JK088_17130	COG1612	heme a metabolic process
JK088_17135	COG0109	protoheme IX farnesyltransferase activity
JK088_17140	COG0545	Peptidyl-prolyl cis-trans isomerase
JK088_17170	COG1278	Cold shock
JK088_17175	COG3036	rescue of stalled ribosome
JK088_17185	COG2199	diguanylate cyclase activity
JK088_17205	COG1136	(ABC) transporter
JK088_17205	COG0577	efflux transmembrane transporter activity
JK088_17215	COG0840	transmembrane signaling receptor activity
JK088_17220	COG0783	Belongs to the Dps family
JK088_17230	COG2133	pyrroloquinoline quinone binding
JK088_17235	COG1454	alcohol dehydrogenase
JK088_17240	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JK088_17280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JK088_17285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JK088_17290	COG3186	Phenylalanine-4-hydroxylase
JK088_17295	COG2154	pterin-4-alpha-carbinolamine dehydratase
JK088_17315	COG3530	Putative quorum-sensing-regulated virulence factor
JK088_17320	COG0513	Belongs to the DEAD box helicase family
JK088_17325	COG4628	conserved protein (DUF2132)
JK088_17330	COG0133	tryptophan synthase activity
JK088_17340	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JK088_17350	COG0523	cobalamin synthesis protein
JK088_17355	COG0513	Belongs to the DEAD box helicase family
JK088_17375	COG2200	EAL domain
JK088_17380	COG1119	ATPase activity
JK088_17385	COG0840	transmembrane signaling receptor activity
JK088_17405	COG0641	radical SAM
JK088_17440	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
JK088_17445	COG0513	Belongs to the DEAD box helicase family
JK088_17450	COG5001	Diguanylate cyclase
JK088_17455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JK088_17470	COG5413	integral membrane protein
JK088_17480	COG1024	Enoyl-CoA hydratase
JK088_17485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JK088_17490	COG1960	acyl-CoA dehydrogenase activity
JK088_17500	COG0183	Belongs to the thiolase family
JK088_17515	COG1024	Enoyl-CoA hydratase
JK088_17520	COG1024	Enoyl-CoA hydratase
JK088_17530	COG1028	Short-chain dehydrogenase reductase Sdr
JK088_17535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JK088_17540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JK088_17545	COG1845	cytochrome c oxidase, subunit III
JK088_17550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JK088_17555	COG0109	protoheme IX farnesyltransferase activity
JK088_17560	COG1902	pentaerythritol trinitrate reductase activity
JK088_17570	COG1126	abc transporter atp-binding protein
JK088_17575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JK088_17580	COG4215	(ABC) transporter
JK088_17585	COG4160	amino acid transport
JK088_17600	COG0625	glutathione transferase activity
JK088_17635	COG0443	Heat shock 70 kDa protein
JK088_17640	COG2847	Copper chaperone PCu(A)C
JK088_17660	COG4607	ABC-type enterochelin transport system periplasmic component
JK088_17665	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JK088_17670	COG4605	iron ion homeostasis
JK088_17675	COG4604	ABC transporter, ATP-binding protein
JK088_17690	COG1629	transport
JK088_17690	COG4771	TonB-dependent receptor
JK088_17720	COG1289	transmembrane transporter activity
JK088_17725	COG0210	DNA helicase
JK088_17730	COG1803	Methylglyoxal synthase
JK088_17735	COG1879	ABC-type sugar transport system periplasmic component
JK088_17740	COG2205	protein histidine kinase activity
JK088_17740	COG2198	Histidine kinase
JK088_17740	COG0784	Response regulator, receiver
JK088_17755	COG0745	RESPONSE REGULATOR receiver
JK088_17760	COG3119	arylsulfatase activity
JK088_17765	COG3119	arylsulfatase activity
JK088_17770	COG3063	Type IV pilus biogenesis stability protein PilW
JK088_17780	COG3119	arylsulfatase activity
JK088_17785	COG0641	radical SAM
JK088_17790	COG0714	Associated with various cellular activities
JK088_17820	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JK088_17825	COG0583	DNA-binding transcription factor activity
JK088_17830	COG1597	lipid kinase activity
JK088_17835	COG3111	PFAM Bacterial OB fold (BOF) protein
JK088_17850	COG0641	radical SAM
JK088_17875	COG0501	Belongs to the peptidase M48B family
JK088_17880	COG1704	LemA family
JK088_17885	COG3069	C4-dicarboxylate transmembrane transporter activity
JK088_17895	COG0456	acetyltransferase
JK088_17895	COG1214	PFAM Peptidase M22, glycoprotease
JK088_17915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JK088_17930	COG0641	radical SAM
JK088_17965	COG2003	Belongs to the UPF0758 family
JK088_17975	COG1609	Transcriptional regulator
JK088_17985	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JK088_18010	COG2084	Dehydrogenase
JK088_18035	COG1454	alcohol dehydrogenase
JK088_18040	COG0235	Class ii aldolase
JK088_18045	COG4806	L-rhamnose isomerase
JK088_18050	COG1070	Carbohydrate kinase
JK088_18055	COG3254	rhamnose metabolic process
JK088_18100	COG1063	alcohol dehydrogenase
JK088_18105	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JK088_18110	COG3959	Transketolase, thiamine diphosphate binding domain
JK088_18125	COG2207	Transcriptional regulator
JK088_18140	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JK088_18140	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JK088_18145	COG0583	DNA-binding transcription factor activity
JK088_18165	COG4964	Belongs to the GSP D family
JK088_18175	COG0455	bacterial-type flagellum organization
JK088_18215	COG2885	chlorophyll binding
JK088_18250	COG0641	radical SAM
JK088_18255	COG4580	involved in the transport of maltose and maltodextrins
JK088_18260	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
JK088_18270	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
JK088_18275	COG1028	Short-chain dehydrogenase reductase Sdr
JK088_18280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JK088_18285	COG0800	Aldolase
JK088_18300	COG3119	arylsulfatase activity
JK088_18305	COG2149	membrane
JK088_18315	COG1518	maintenance of DNA repeat elements
JK088_18350	COG0840	transmembrane signaling receptor activity
JK088_18355	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JK088_18365	COG0457	Tetratricopeptide repeat
JK088_18370	COG2814	Major facilitator Superfamily
JK088_18370	COG0477	Major facilitator Superfamily
JK088_18380	COG1940	carbohydrate kinase activity
JK088_18385	COG0737	Belongs to the 5'-nucleotidase family
JK088_18425	COG0494	nUDIX hydrolase
JK088_18450	COG0582	viral genome integration into host DNA
JK088_18475	COG2207	Transcriptional regulator
JK088_18500	COG4964	Belongs to the GSP D family
JK088_18560	COG0583	DNA-binding transcription factor activity
JK088_18565	COG0583	DNA-binding transcription factor activity
JK088_18580	COG3300	MHYT domain
JK088_18580	COG5001	Diguanylate cyclase
JK088_18585	COG2197	response regulator
JK088_18590	COG3706	GGDEF domain
JK088_18600	COG2197	response regulator
JK088_18620	COG0784	Response regulator, receiver
JK088_18620	COG0835	chemotaxis
JK088_18635	COG2962	Rard protein
JK088_18645	COG0671	phosphoesterase, PA-phosphatase related
JK088_18660	COG2076	Multidrug Resistance protein
JK088_18690	COG0471	metal ion transport
JK088_18695	COG3290	protein histidine kinase activity
JK088_18700	COG4565	transcriptional regulatory protein
JK088_18715	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JK088_18720	COG5642	Protein of unknown function (DUF2384)
JK088_18740	COG1902	pentaerythritol trinitrate reductase activity
JK088_18745	COG0346	lactoylglutathione lyase activity
JK088_18765	COG2239	Acts as a magnesium transporter
JK088_18795	COG0242	peptide deformylase activity
JK088_18840	COG2176	DNA-directed DNA polymerase activity
JK088_18845	COG0583	DNA-binding transcription factor activity
JK088_18850	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JK088_18885	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JK088_18885	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JK088_18890	COG0509	glycine decarboxylation via glycine cleavage system
JK088_18895	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JK088_18935	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JK088_18935	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JK088_18935	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JK088_18940	COG1105	Belongs to the carbohydrate kinase PfkB family
JK088_18945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JK088_18945	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JK088_18950	COG1609	Transcriptional regulator
JK088_18965	COG2203	Gaf domain
JK088_18965	COG2199	diguanylate cyclase activity
JK088_18965	COG2200	EAL domain
JK088_18970	COG0765	amino acid transport
JK088_18975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JK088_18980	COG0765	amino acid transport
JK088_18985	COG1126	abc transporter atp-binding protein
JK088_18990	COG0469	pyruvate kinase activity
JK088_18995	COG2271	Major facilitator Superfamily
JK088_19020	COG1979	alcohol dehydrogenase
JK088_19025	COG2207	Transcriptional regulator
JK088_19035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JK088_19040	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JK088_19045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JK088_19060	COG3437	response regulator, receiver
JK088_19060	COG0784	Response regulator, receiver
JK088_19065	COG0546	phosphoglycolate phosphatase activity
JK088_19070	COG0840	transmembrane signaling receptor activity
JK088_19075	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
JK088_19080	COG0513	Belongs to the DEAD box helicase family
JK088_19085	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JK088_19100	COG3038	cytochrome b561
JK088_19105	COG2353	YceI-like domain
JK088_19110	COG2116	formate transmembrane transporter activity
JK088_19115	COG0583	DNA-binding transcription factor activity
JK088_19125	COG3593	DNA synthesis involved in DNA repair
JK088_19130	COG0737	Belongs to the 5'-nucleotidase family
JK088_19135	COG0861	Integral membrane protein TerC family
JK088_19150	COG2267	carboxylic ester hydrolase activity
JK088_19155	COG2067	long-chain fatty acid transport protein
JK088_19170	COG2050	protein possibly involved in aromatic compounds catabolism
JK088_19180	COG4533	DNA binding
JK088_19205	COG0484	heat shock protein binding
JK088_19215	COG5001	Diguanylate cyclase
JK088_19215	COG3300	MHYT domain
JK088_19220	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JK088_19230	COG4181	ATPase activity
JK088_19235	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JK088_19245	COG1984	allophanate hydrolase subunit 2
JK088_19250	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JK088_19255	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JK088_19260	COG3447	MASE1 domain protein
JK088_19260	COG5001	Diguanylate cyclase
JK088_19260	COG5002	protein histidine kinase activity
JK088_19265	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JK088_19275	COG0583	DNA-binding transcription factor activity
JK088_19280	COG0045	succinate-CoA ligase (ADP-forming) activity
JK088_19280	COG1042	CoA-binding domain protein
JK088_19280	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JK088_19290	COG1181	Belongs to the D-alanine--D-alanine ligase family
JK088_19300	COG0023	Translation Initiation Factor
JK088_19350	COG4128	Pfam Zonular occludens toxin
JK088_19375	COG0583	DNA-binding transcription factor activity
JK088_19385	COG0589	response to stress
JK088_19390	COG3140	Belongs to the UPF0181 family
JK088_19415	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JK088_19420	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JK088_19445	COG2203	Gaf domain
JK088_19445	COG5001	Diguanylate cyclase
JK088_19445	COG3706	GGDEF domain
JK088_19445	COG4251	negative regulation of phosphorylation
JK088_19455	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JK088_19460	COG4149	molybdate abc transporter
JK088_19465	COG0725	ABC transporter, periplasmic molybdate-binding protein
JK088_19470	COG1492	cobalamin metabolic process
JK088_19475	COG3111	PFAM Bacterial OB fold (BOF) protein
JK088_19485	COG4067	protein conserved in archaea
JK088_19485	COG0189	ligase activity
JK088_19500	COG0534	Mate efflux family protein
JK088_19505	COG0602	queuosine metabolic process
JK088_19510	COG1328	CTP reductase activity
JK088_19525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JK088_19555	COG0243	molybdopterin cofactor binding
JK088_19560	COG0583	DNA-binding transcription factor activity
JK088_19565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JK088_19575	COG2197	response regulator
JK088_19580	COG3851	Histidine kinase
JK088_19585	COG2271	Major facilitator Superfamily
JK088_19610	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JK088_19615	COG3118	belongs to the thioredoxin family
JK088_19625	COG3292	Two component regulator propeller
JK088_19625	COG0745	RESPONSE REGULATOR receiver
JK088_19625	COG2205	protein histidine kinase activity
JK088_19630	COG0534	Mate efflux family protein
JK088_19660	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JK088_19680	COG2116	formate transmembrane transporter activity
JK088_19690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JK088_19695	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JK088_19735	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JK088_19735	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JK088_19775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JK088_19790	COG0277	FAD linked oxidase domain protein
JK088_19795	COG0583	DNA-binding transcription factor activity
JK088_19810	COG2425	protein containing a von Willebrand factor type A (vWA) domain
JK088_19825	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
JK088_19835	COG1288	antiporter activity
JK088_19845	COG2814	Major facilitator Superfamily
JK088_19855	COG3040	lipid binding
JK088_19875	COG0419	ATPase involved in DNA repair
JK088_19880	COG0420	3'-5' exonuclease activity
JK088_19950	COG0631	protein serine/threonine phosphatase activity
JK088_19985	COG0515	serine threonine protein kinase
JK088_19985	COG2815	serine threonine protein kinase
JK088_20040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JK088_20040	COG2146	nitrite reductase [NAD(P)H] activity
JK088_20045	COG1116	anion transmembrane transporter activity
JK088_20050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JK088_20055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JK088_20060	COG3707	response regulator
JK088_20080	COG0243	molybdopterin cofactor binding
JK088_20090	COG0814	amino acid
JK088_20115	COG1785	Belongs to the alkaline phosphatase family
JK088_20130	COG0745	RESPONSE REGULATOR receiver
JK088_20150	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JK088_20165	COG1609	Transcriptional regulator
JK088_20170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JK088_20175	COG1879	ABC-type sugar transport system periplasmic component
JK088_20180	COG1172	Belongs to the binding-protein-dependent transport system permease family
JK088_20185	COG1129	ABC transporter
JK088_20190	COG1869	D-ribose catabolic process
JK088_20195	COG5001	Diguanylate cyclase
JK088_20200	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JK088_20255	COG0784	Response regulator, receiver
JK088_20255	COG2205	protein histidine kinase activity
JK088_20265	COG3300	MHYT domain
JK088_20265	COG5001	Diguanylate cyclase
JK088_20275	COG0330	HflC and HflK could
JK088_20290	COG0517	IMP dehydrogenase activity
JK088_20290	COG4175	Glycine betaine
JK088_20295	COG4176	ABC-type proline glycine betaine transport system permease component
JK088_20310	COG1012	belongs to the aldehyde dehydrogenase family
JK088_20315	COG1309	transcriptional regulator
JK088_20320	COG3706	GGDEF domain
JK088_20325	COG1028	Short-chain dehydrogenase reductase Sdr
JK088_20340	COG1024	Enoyl-CoA hydratase
JK088_20345	COG1960	acyl-CoA dehydrogenase activity
JK088_20355	COG0183	Belongs to the thiolase family
JK088_20365	COG1960	acyl-CoA dehydrogenase activity
JK088_20370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JK088_20390	COG2205	protein histidine kinase activity
JK088_20390	COG3437	response regulator, receiver
JK088_20390	COG4999	Histidine kinase
JK088_20390	COG3850	Histidine kinase
JK088_20405	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JK088_20405	COG3264	Mechanosensitive ion channel
JK088_20410	COG0110	maltose O-acetyltransferase activity
JK088_20415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JK088_20420	COG1271	oxidase subunit
JK088_20425	COG1294	oxidase, subunit
JK088_20435	COG0384	phenazine biosynthesis protein PhzF
JK088_20440	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JK088_20445	COG0789	Transcriptional regulator
JK088_20455	COG3474	cytochrome
JK088_20520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JK088_20525	COG0516	GMP reductase activity
JK088_20530	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JK088_20530	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JK088_20545	COG4989	oxidoreductase activity
JK088_20560	COG0038	chloride channel
JK088_20570	COG1914	H( )-stimulated, divalent metal cation uptake system
JK088_20575	COG0302	gtp cyclohydrolase
JK088_20585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JK088_20605	COG2897	thiosulfate sulfurtransferase activity
JK088_20625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JK088_20630	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JK088_20640	COG2814	Major facilitator Superfamily
JK088_20645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JK088_20655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JK088_20665	COG0840	transmembrane signaling receptor activity
JK088_20685	COG2195	Cleaves the N-terminal amino acid of tripeptides
JK088_20700	COG2197	response regulator
JK088_20705	COG3850	Histidine kinase
JK088_20710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JK088_20720	COG0243	molybdopterin cofactor binding
JK088_20730	COG3005	denitrification pathway
JK088_20750	COG0183	Belongs to the thiolase family
JK088_20770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JK088_20775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JK088_20800	COG1522	sequence-specific DNA binding
JK088_20820	COG1566	PFAM secretion protein HlyD family protein
JK088_20830	COG0784	Response regulator, receiver
JK088_20830	COG2205	protein histidine kinase activity
JK088_20835	COG1879	ABC-type sugar transport system periplasmic component
JK088_20840	COG2827	Endonuclease containing a URI domain
JK088_20845	COG3132	Protein of unknown function, DUF480
JK088_20855	COG2926	Belongs to the UPF0265 family
JK088_20860	COG0534	Mate efflux family protein
JK088_20865	COG0673	inositol 2-dehydrogenase activity
JK088_20870	COG0784	Response regulator, receiver
JK088_20870	COG5002	protein histidine kinase activity
JK088_20870	COG2205	protein histidine kinase activity
JK088_20890	COG0583	DNA-binding transcription factor activity
JK088_20895	COG1522	sequence-specific DNA binding
JK088_20900	COG0531	amino acid
JK088_20915	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JK088_20920	COG2239	Acts as a magnesium transporter
JK088_20925	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JK088_20930	COG0402	S-adenosylhomocysteine deaminase activity
JK088_20940	COG1418	mRNA catabolic process
JK088_20960	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JK088_20980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JK088_20995	COG4221	oxidoreductase activity
JK088_21000	COG0745	RESPONSE REGULATOR receiver
JK088_21005	COG2205	protein histidine kinase activity
JK088_21015	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JK088_21020	COG2194	sulfuric ester hydrolase activity
JK088_21025	COG0673	inositol 2-dehydrogenase activity
JK088_21035	COG2814	Major facilitator Superfamily
JK088_21060	COG4667	esterase of the alpha-beta hydrolase superfamily
JK088_21065	COG1741	Belongs to the pirin family
JK088_21070	COG1278	Cold shock
JK088_21085	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JK088_21110	COG1686	Belongs to the peptidase S11 family
JK088_21115	COG0625	glutathione transferase activity
JK088_21125	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JK088_21155	COG1073	alpha beta
JK088_21160	COG0583	DNA-binding transcription factor activity
JK088_21200	COG1028	Short-chain dehydrogenase reductase Sdr
JK088_21215	COG3746	phosphate-selective porin O and P
JK088_21235	COG3833	ABC-type maltose transport systems, permease component
JK088_21240	COG1175	transmembrane transport
JK088_21250	COG3842	ATPase activity
JK088_21280	COG0438	transferase activity, transferring glycosyl groups
JK088_21310	COG3097	Belongs to the UPF0267 family
JK088_21315	COG1309	transcriptional regulator
JK088_21320	COG2130	NADP-dependent
JK088_21330	COG0753	catalase activity
JK088_21335	COG2084	Dehydrogenase
JK088_21340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JK088_21345	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JK088_21355	COG2207	Transcriptional regulator
JK088_21360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JK088_21360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JK088_21360	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JK088_21375	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JK088_21380	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
JK088_21390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JK088_21395	COG0569	domain protein
JK088_21400	COG0745	RESPONSE REGULATOR receiver
JK088_21405	COG2205	protein histidine kinase activity
JK088_21405	COG2205	protein histidine kinase activity
JK088_21410	COG1132	(ABC) transporter
JK088_21415	COG4774	siderophore transport
JK088_21420	COG1120	ATPase activity
JK088_21425	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JK088_21460	COG2197	response regulator
JK088_21470	COG0840	transmembrane signaling receptor activity
JK088_21475	COG0714	Associated with various cellular activities
JK088_21495	COG2304	oxidoreductase activity
JK088_21515	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JK088_21520	COG0581	inorganic phosphate transmembrane transporter activity
JK088_21525	COG0573	inorganic phosphate transmembrane transporter activity
JK088_21555	COG4771	TonB-dependent receptor
JK088_21560	COG1770	oligopeptidase
JK088_21565	COG0513	Belongs to the DEAD box helicase family
JK088_21575	COG1388	LysM domain
JK088_21575	COG1376	ErfK ybiS ycfS ynhG family protein
JK088_21580	COG0415	Belongs to the DNA photolyase family
JK088_21585	COG0789	Transcriptional regulator
JK088_21590	COG3272	Protein of unknown function (DUF1722)
JK088_21595	COG0813	purine-nucleoside phosphorylase activity
JK088_21610	COG3706	GGDEF domain
JK088_21620	COG1566	PFAM secretion protein HlyD family protein
JK088_21625	COG4720	Psort location CytoplasmicMembrane, score
JK088_21630	COG1122	ATPase activity
JK088_21645	COG0348	domain, Protein
JK088_21650	COG0437	4 iron, 4 sulfur cluster binding
JK088_21655	COG1247	-acetyltransferase
JK088_21680	COG1067	ATP-dependent peptidase activity
JK088_21690	COG4172	Belongs to the ABC transporter superfamily
JK088_21695	COG1505	serine-type exopeptidase activity
JK088_21700	COG0583	DNA-binding transcription factor activity
JK088_21705	COG1620	l-lactate permease
JK088_21710	COG1304	FMN binding
JK088_21720	COG0668	transmembrane transport
JK088_21755	COG1063	alcohol dehydrogenase
JK088_21760	COG0156	8-amino-7-oxononanoate synthase activity
JK088_21770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JK088_21790	COG0745	RESPONSE REGULATOR receiver
JK088_21815	COG0346	lactoylglutathione lyase activity
JK088_21835	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JK088_21915	COG1987	bacterial-type flagellum assembly
JK088_21925	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JK088_21940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JK088_21960	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JK088_21965	COG1516	flagellar protein fliS
JK088_21980	COG1580	Controls the rotational direction of flagella during chemotaxis
JK088_21985	COG1191	sigma factor activity
JK088_21990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JK088_21995	COG1360	Flagellar Motor Protein
JK088_22025	COG1882	Formate acetyltransferase
JK088_22030	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JK088_22035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JK088_22045	COG0454	-acetyltransferase
JK088_22055	COG2814	Major facilitator Superfamily
JK088_22095	COG0628	permease
JK088_22100	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JK088_22110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JK088_22120	COG4628	conserved protein (DUF2132)
JK088_22125	COG0583	DNA-binding transcription factor activity
JK088_22150	COG1686	Belongs to the peptidase S11 family
JK088_22165	COG1054	Belongs to the UPF0176 family
JK088_22170	COG3397	chitin binding
JK088_22175	COG4667	esterase of the alpha-beta hydrolase superfamily
JK088_22180	COG2095	MarC family integral membrane protein
JK088_22200	COG3206	protein involved in exopolysaccharide biosynthesis
JK088_22200	COG0489	protein tyrosine kinase activity
JK088_22215	COG0583	DNA-binding transcription factor activity
JK088_22225	COG1301	dicarboxylic acid transport
JK088_22230	COG3339	Conserved Protein
JK088_22235	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JK088_22240	COG0700	Nucleoside recognition
JK088_22245	COG3366	ferrous iron transmembrane transporter activity
JK088_22255	COG0366	Alpha amylase catalytic
JK088_22260	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JK088_22265	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JK088_22270	COG1640	4-alpha-glucanotransferase
JK088_22275	COG0058	SHG alpha-glucan phosphorylase activity
JK088_22280	COG2909	trisaccharide binding
JK088_22295	COG1999	signal sequence binding
JK088_22305	COG1263	PTS System
JK088_22305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JK088_22310	COG1162	GTPase activity
JK088_22315	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JK088_22325	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JK088_22335	COG0531	amino acid
JK088_22340	COG1982	Orn Lys Arg decarboxylase major
JK088_22360	COG2356	endonuclease I
JK088_22380	COG4580	involved in the transport of maltose and maltodextrins
JK088_22395	COG2814	Major facilitator Superfamily
JK088_22405	COG0739	heme binding
JK088_22415	COG0612	Peptidase, M16
JK088_22420	COG0840	transmembrane signaling receptor activity
JK088_22425	COG1120	ATPase activity
JK088_22430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JK088_22435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JK088_22440	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JK088_22470	COG4264	IucA IucC family
JK088_22475	COG0019	diaminopimelate decarboxylase activity
JK088_22480	COG1653	transport
JK088_22505	COG0826	peptidase U32
JK088_22510	COG1172	Belongs to the binding-protein-dependent transport system permease family
JK088_22515	COG1129	ABC transporter
JK088_22520	COG1879	ABC-type sugar transport system periplasmic component
JK088_22525	COG1069	ribulokinase activity
JK088_22535	COG2160	L-arabinose isomerase activity
JK088_22560	COG1764	response to oxidative stress
JK088_22565	COG1846	Transcriptional regulator
JK088_22575	COG3634	alkyl hydroperoxide reductase activity
JK088_22600	COG1595	DNA-templated transcription, initiation
JK088_22615	COG0583	DNA-binding transcription factor activity
JK088_22620	COG1486	melibiose metabolic process
JK088_22635	COG2258	MOSC domain
JK088_22640	COG0513	Belongs to the DEAD box helicase family
JK088_22645	COG1312	Catalyzes the dehydration of D-mannonate
JK088_22650	COG2186	Transcriptional regulator
JK088_22660	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JK088_22670	COG0246	Mannitol dehydrogenase
JK088_22675	COG1904	glucuronate isomerase
JK088_22680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JK088_22685	COG0800	Aldolase
JK088_22705	COG2207	Transcriptional regulator
JK088_22715	COG1132	(ABC) transporter
JK088_22760	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JK088_22785	COG0259	pyridoxamine-phosphate oxidase activity
JK088_22830	COG4166	transmembrane transport
JK088_22845	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JK088_22850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JK088_22850	COG1263	PTS System
JK088_22855	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JK088_22860	COG3340	Belongs to the peptidase S51 family
JK088_22880	COG1444	tRNA N-acetyltransferase activity
JK088_22905	COG4608	Belongs to the ABC transporter superfamily
JK088_22910	COG0444	Belongs to the ABC transporter superfamily
JK088_22920	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
JK088_22920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JK088_22940	COG0217	transcriptional regulatory protein
JK088_22945	COG0772	Belongs to the SEDS family
JK088_22975	COG3275	phosphorelay sensor kinase activity
JK088_22980	COG3279	Response regulator of the LytR AlgR family
JK088_22990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JK088_23015	COG0786	glutamate:sodium symporter activity
JK088_23025	COG1131	(ABC) transporter
JK088_23030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JK088_23035	COG0786	glutamate:sodium symporter activity
JK088_23045	COG0363	glucosamine-6-phosphate deaminase activity
JK088_23065	COG1741	Belongs to the pirin family
JK088_23070	COG2259	Doxx family
JK088_23080	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JK088_23085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JK088_23095	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JK088_23135	COG3123	guanosine phosphorylase activity
JK088_23145	COG5001	Diguanylate cyclase
JK088_23150	COG0534	Mate efflux family protein
JK088_23155	COG0564	pseudouridine synthase activity
JK088_23170	COG0583	DNA-binding transcription factor activity
JK088_23175	COG0561	phosphatase activity
JK088_23185	COG2199	diguanylate cyclase activity
JK088_23200	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JK088_23205	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JK088_23210	COG0583	DNA-binding transcription factor activity
JK088_23225	COG1414	Transcriptional regulator
JK088_23230	COG1028	Short-chain dehydrogenase reductase Sdr
JK088_23240	COG1917	Cupin 2, conserved barrel domain protein
JK088_23255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JK088_23260	COG0800	Aldolase
JK088_23280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JK088_23285	COG0823	Involved in the tonB-independent uptake of proteins
JK088_23290	COG2375	cellular response to nickel ion
JK088_23320	COG1357	PFAM Pentapeptide repeats (8 copies)
JK088_23325	COG3047	cAMP biosynthetic process
JK088_23355	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
JK088_23355	COG3408	Glycogen debranching enzyme
JK088_23360	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JK088_23370	COG0583	DNA-binding transcription factor activity
JK088_23380	COG0583	DNA-binding transcription factor activity
JK088_23385	COG0641	radical SAM
JK088_23400	COG0583	DNA-binding transcription factor activity
JK088_23415	COG0546	phosphoglycolate phosphatase activity
JK088_23440	COG3835	regulator
JK088_23445	COG2610	gluconate transmembrane transporter activity
JK088_23455	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JK088_23475	COG0454	-acetyltransferase
JK088_23475	COG0456	acetyltransferase
JK088_23490	COG1028	Short-chain dehydrogenase reductase Sdr
JK088_23500	COG3005	denitrification pathway
JK088_23505	COG0243	molybdopterin cofactor binding
JK088_23515	COG0352	thiamine-phosphate diphosphorylase activity
JK088_23520	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JK088_23525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JK088_23530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JK088_23535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JK088_23545	COG0351	phosphomethylpyrimidine kinase
JK088_23550	COG0312	modulator of DNA gyrase
JK088_23555	COG0312	modulator of DNA gyrase
JK088_23560	COG1901	pseudouridine methyltransferase
JK088_23615	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JK088_23625	COG0584	glycerophosphoryl diester phosphodiesterase
JK088_23630	COG0039	L-malate dehydrogenase activity
JK088_23635	COG0745	RESPONSE REGULATOR receiver
JK088_23655	COG0811	peptide transport
JK088_23660	COG0811	peptide transport
JK088_23665	COG0848	biopolymer transport protein
JK088_23705	COG0803	Belongs to the bacterial solute-binding protein 9 family
JK088_23710	COG1121	(ABC) transporter
JK088_23715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JK088_23730	COG1770	oligopeptidase
JK088_23735	COG2814	Major facilitator Superfamily
JK088_23740	COG0010	Belongs to the arginase family
JK088_23745	COG1166	arginine decarboxylase activity
JK088_23755	COG0189	ligase activity
JK088_23755	COG4067	protein conserved in archaea
JK088_23760	COG0189	ligase activity
JK088_23765	COG0583	DNA-binding transcription factor activity
JK088_23805	COG2199	diguanylate cyclase activity
JK088_23810	COG1114	Component of the transport system for branched-chain amino acids
JK088_23825	COG0579	oxidoreductase
JK088_23835	COG3033	Beta-eliminating lyase
JK088_23850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JK088_23865	COG3706	GGDEF domain
JK088_23870	COG0840	transmembrane signaling receptor activity
JK088_23885	COG3706	GGDEF domain
JK088_23890	COG0415	Belongs to the DNA photolyase family
JK088_23895	COG3046	protein related to deoxyribodipyrimidine photolyase
JK088_23910	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JK088_23910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JK088_23915	COG1765	OsmC-like protein
JK088_23920	COG0110	maltose O-acetyltransferase activity
JK088_23960	COG1011	Hydrolase
JK088_23975	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JK088_23985	COG2067	long-chain fatty acid transport protein
JK088_23990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JK088_23995	COG1136	(ABC) transporter
JK088_23995	COG0577	efflux transmembrane transporter activity
JK088_24005	COG3240	lipase activity
JK088_24035	COG1609	Transcriptional regulator
JK088_24040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JK088_24045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JK088_24050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JK088_24055	COG1840	ABC-type Fe3 transport system, periplasmic component
JK088_24065	COG3842	ATPase activity
JK088_24090	COG2990	Protein conserved in bacteria
JK088_24095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JK088_24100	COG2866	Carboxypeptidase
JK088_24110	COG0583	DNA-binding transcription factor activity
JK088_24130	COG3104	oligopeptide transport
JK088_24135	COG1760	l-serine dehydratase
JK088_24155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JK088_24160	COG0741	lytic transglycosylase activity
JK088_24180	COG1815	bacterial-type flagellum-dependent cell motility
JK088_24185	COG1558	bacterial-type flagellum-dependent cell motility
JK088_24190	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JK088_24195	COG1749	Flagellar hook protein flgE
JK088_24200	COG4787	bacterial-type flagellum-dependent cell motility
JK088_24205	COG4786	Flagellar basal body rod
JK088_24210	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JK088_24215	COG1706	bacterial-type flagellum-dependent cell motility
JK088_24225	COG4786	Flagellar basal body rod
JK088_24225	COG1256	bacterial-type flagellum assembly
JK088_24230	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JK088_24250	COG1304	FMN binding
JK088_24275	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JK088_24280	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JK088_24285	COG0459	protein refolding
JK088_24300	COG1280	lysine exporter protein (LysE YggA)
JK088_24320	COG1309	transcriptional regulator
JK088_24330	COG0737	Belongs to the 5'-nucleotidase family
JK088_24335	COG2070	2-Nitropropane dioxygenase
JK088_24340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JK088_24350	COG0583	DNA-binding transcription factor activity
JK088_24365	COG0346	lactoylglutathione lyase activity
JK088_24370	COG1349	DNA-binding transcription factor activity
JK088_24400	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JK088_24420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JK088_24450	COG3093	addiction module antidote protein HigA
JK088_24465	COG1192	Involved in chromosome partitioning
JK088_24510	COG2856	Zn peptidase
JK088_24605	COG5001	Diguanylate cyclase
JK088_24675	COG4974	Belongs to the 'phage' integrase family
JK088_24690	COG3121	Chaperone
JK088_24700	COG3188	usher protein
JK088_24710	COG3539	Fimbrial protein
JK088_24720	COG1227	inorganic diphosphatase activity
JK088_24730	COG0148	phosphopyruvate hydratase activity
JK088_24735	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JK088_24740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JK088_24765	COG3038	cytochrome b561
JK088_24775	COG0204	Acyl-transferase
JK088_24775	COG0318	PFAM AMP-dependent synthetase and ligase
JK088_24785	COG0300	oxidoreductase activity
JK088_24815	COG0840	transmembrane signaling receptor activity
JK088_24880	COG2948	multi-organism process
JK088_24885	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis