locus-tag	class	description
FDP11_00015	COG0573	inorganic phosphate transmembrane transporter activity
FDP11_00020	COG0581	inorganic phosphate transmembrane transporter activity
FDP11_00025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDP11_00040	COG2304	oxidoreductase activity
FDP11_00060	COG0714	Associated with various cellular activities
FDP11_00070	COG0840	transmembrane signaling receptor activity
FDP11_00115	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FDP11_00120	COG1120	ATPase activity
FDP11_00125	COG4774	siderophore transport
FDP11_00130	COG1132	(ABC) transporter
FDP11_00135	COG2205	protein histidine kinase activity
FDP11_00145	COG0569	domain protein
FDP11_00150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDP11_00160	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FDP11_00165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDP11_00180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP11_00180	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDP11_00180	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDP11_00185	COG2207	Transcriptional regulator
FDP11_00195	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDP11_00200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDP11_00205	COG2084	Dehydrogenase
FDP11_00210	COG0753	catalase activity
FDP11_00220	COG2130	NADP-dependent
FDP11_00225	COG1309	transcriptional regulator
FDP11_00260	COG0438	transferase activity, transferring glycosyl groups
FDP11_00285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FDP11_00290	COG3842	ATPase activity
FDP11_00300	COG1175	transmembrane transport
FDP11_00305	COG3833	ABC-type maltose transport systems, permease component
FDP11_00335	COG2354	Protein conserved in bacteria
FDP11_00340	COG0418	dihydroorotase activity
FDP11_00350	COG0401	homolog of Blt101
FDP11_00360	COG0633	Ferredoxin
FDP11_00360	COG3217	Mosc domain protein beta barrel domain protein
FDP11_00360	COG3217	Mosc domain protein beta barrel domain protein
FDP11_00360	COG0633	Ferredoxin
FDP11_00365	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FDP11_00370	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FDP11_00415	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FDP11_00420	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDP11_00430	COG0848	biopolymer transport protein
FDP11_00435	COG0811	peptide transport
FDP11_00440	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FDP11_00450	COG3721	Heme iron utilization protein
FDP11_00455	COG0748	coenzyme F420 binding
FDP11_00465	COG0784	Response regulator, receiver
FDP11_00465	COG0835	chemotaxis
FDP11_00475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDP11_00490	COG2814	Major facilitator Superfamily
FDP11_00500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDP11_00540	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FDP11_00545	COG0783	Belongs to the Dps family
FDP11_00555	COG0583	DNA-binding transcription factor activity
FDP11_00570	COG4934	collagen metabolic process
FDP11_00580	COG0366	Alpha amylase catalytic
FDP11_00600	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDP11_00605	COG0589	response to stress
FDP11_00610	COG0488	(ABC) transporter
FDP11_00625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDP11_00635	COG2067	long-chain fatty acid transport protein
FDP11_00645	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDP11_00655	COG2203	Gaf domain
FDP11_00655	COG2199	diguanylate cyclase activity
FDP11_00675	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDP11_00700	COG3383	formate dehydrogenase (NAD+) activity
FDP11_00715	COG0842	Transport permease protein
FDP11_00720	COG1131	(ABC) transporter
FDP11_00740	COG2706	6-phosphogluconolactonase activity
FDP11_00750	COG1881	PFAM PEBP family protein
FDP11_00760	COG0798	PFAM Bile acid sodium symporter
FDP11_00780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP11_00785	COG2213	PTS system mannitol-specific
FDP11_00790	COG1063	alcohol dehydrogenase
FDP11_00800	COG1072	(Pantothenic acid kinase))
FDP11_00805	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FDP11_00825	COG0814	amino acid
FDP11_00865	COG0739	heme binding
FDP11_00870	COG5001	Diguanylate cyclase
FDP11_00875	COG0583	DNA-binding transcription factor activity
FDP11_00880	COG2814	Major facilitator Superfamily
FDP11_00905	COG0697	spore germination
FDP11_00935	COG2207	Transcriptional regulator
FDP11_00940	COG1280	lysine exporter protein (LysE YggA)
FDP11_00950	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDP11_00955	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FDP11_00965	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FDP11_00990	COG1612	heme a metabolic process
FDP11_00995	COG0109	protoheme IX farnesyltransferase activity
FDP11_01000	COG0545	Peptidyl-prolyl cis-trans isomerase
FDP11_01035	COG1278	Cold shock
FDP11_01040	COG3036	rescue of stalled ribosome
FDP11_01055	COG2199	diguanylate cyclase activity
FDP11_01075	COG0577	efflux transmembrane transporter activity
FDP11_01075	COG1136	(ABC) transporter
FDP11_01085	COG0840	transmembrane signaling receptor activity
FDP11_01090	COG0783	Belongs to the Dps family
FDP11_01100	COG2133	pyrroloquinoline quinone binding
FDP11_01105	COG1454	alcohol dehydrogenase
FDP11_01110	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FDP11_01150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FDP11_01155	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDP11_01160	COG3186	Phenylalanine-4-hydroxylase
FDP11_01165	COG2154	pterin-4-alpha-carbinolamine dehydratase
FDP11_01190	COG3530	Putative quorum-sensing-regulated virulence factor
FDP11_01195	COG0513	Belongs to the DEAD box helicase family
FDP11_01200	COG4628	conserved protein (DUF2132)
FDP11_01205	COG0133	tryptophan synthase activity
FDP11_01215	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FDP11_01225	COG0523	cobalamin synthesis protein
FDP11_01230	COG0513	Belongs to the DEAD box helicase family
FDP11_01250	COG2200	EAL domain
FDP11_01255	COG1119	ATPase activity
FDP11_01260	COG0840	transmembrane signaling receptor activity
FDP11_01285	COG0641	radical SAM
FDP11_01305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FDP11_01320	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FDP11_01325	COG0513	Belongs to the DEAD box helicase family
FDP11_01330	COG5001	Diguanylate cyclase
FDP11_01340	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FDP11_01355	COG5413	integral membrane protein
FDP11_01365	COG1024	Enoyl-CoA hydratase
FDP11_01370	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDP11_01375	COG1960	acyl-CoA dehydrogenase activity
FDP11_01385	COG0183	Belongs to the thiolase family
FDP11_01400	COG1024	Enoyl-CoA hydratase
FDP11_01405	COG1024	Enoyl-CoA hydratase
FDP11_01415	COG1028	Short-chain dehydrogenase reductase Sdr
FDP11_01420	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FDP11_01425	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FDP11_01430	COG1845	cytochrome c oxidase, subunit III
FDP11_01435	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FDP11_01440	COG0109	protoheme IX farnesyltransferase activity
FDP11_01455	COG1902	pentaerythritol trinitrate reductase activity
FDP11_01465	COG1126	abc transporter atp-binding protein
FDP11_01470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDP11_01475	COG4215	(ABC) transporter
FDP11_01480	COG4160	amino acid transport
FDP11_01495	COG0625	glutathione transferase activity
FDP11_01535	COG0443	Heat shock 70 kDa protein
FDP11_01540	COG2847	Copper chaperone PCu(A)C
FDP11_01570	COG0745	RESPONSE REGULATOR receiver
FDP11_01585	COG1785	Belongs to the alkaline phosphatase family
FDP11_01615	COG0814	amino acid
FDP11_01625	COG0243	molybdopterin cofactor binding
FDP11_01630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FDP11_01630	COG1648	precorrin-2 dehydrogenase activity
FDP11_01650	COG3707	response regulator
FDP11_01660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDP11_01665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDP11_01670	COG1116	anion transmembrane transporter activity
FDP11_01675	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDP11_01675	COG2146	nitrite reductase [NAD(P)H] activity
FDP11_01730	COG2815	serine threonine protein kinase
FDP11_01730	COG0515	serine threonine protein kinase
FDP11_01765	COG0631	protein serine/threonine phosphatase activity
FDP11_01820	COG3501	Rhs element vgr protein
FDP11_01840	COG0419	ATPase involved in DNA repair
FDP11_01860	COG3040	lipid binding
FDP11_01870	COG2814	Major facilitator Superfamily
FDP11_01895	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FDP11_01915	COG0641	radical SAM
FDP11_01950	COG2003	Belongs to the UPF0758 family
FDP11_01965	COG4565	transcriptional regulatory protein
FDP11_01975	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FDP11_01980	COG0511	ligase activity, forming carbon-carbon bonds
FDP11_01980	COG5016	pyruvate
FDP11_01985	COG3630	sodium ion export across plasma membrane
FDP11_01995	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FDP11_02005	COG2301	Belongs to the HpcH HpaI aldolase family
FDP11_02020	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FDP11_02085	COG1454	alcohol dehydrogenase
FDP11_02090	COG0235	Class ii aldolase
FDP11_02095	COG4806	L-rhamnose isomerase
FDP11_02100	COG1070	Carbohydrate kinase
FDP11_02105	COG3254	rhamnose metabolic process
FDP11_02165	COG0840	transmembrane signaling receptor activity
FDP11_02170	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FDP11_02180	COG3710	Transcriptional regulator
FDP11_02225	COG0457	Tetratricopeptide repeat
FDP11_02230	COG2814	Major facilitator Superfamily
FDP11_02230	COG0477	Major facilitator Superfamily
FDP11_02240	COG1940	carbohydrate kinase activity
FDP11_02245	COG0737	Belongs to the 5'-nucleotidase family
FDP11_02265	COG1715	Restriction endonuclease
FDP11_02270	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FDP11_02275	COG0732	type I restriction modification DNA specificity domain
FDP11_02290	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FDP11_02310	COG0583	DNA-binding transcription factor activity
FDP11_02325	COG5001	Diguanylate cyclase
FDP11_02325	COG3300	MHYT domain
FDP11_02330	COG2197	response regulator
FDP11_02335	COG3706	GGDEF domain
FDP11_02345	COG2197	response regulator
FDP11_02370	COG0784	Response regulator, receiver
FDP11_02370	COG0835	chemotaxis
FDP11_02390	COG2962	Rard protein
FDP11_02405	COG0671	phosphoesterase, PA-phosphatase related
FDP11_02415	COG1288	antiporter activity
FDP11_02430	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FDP11_02445	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FDP11_02465	COG0583	DNA-binding transcription factor activity
FDP11_02470	COG0277	FAD linked oxidase domain protein
FDP11_02490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDP11_02535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDP11_02535	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDP11_02580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDP11_02585	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDP11_02595	COG2116	formate transmembrane transporter activity
FDP11_02615	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FDP11_02665	COG3118	belongs to the thioredoxin family
FDP11_02670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FDP11_02695	COG2271	Major facilitator Superfamily
FDP11_02700	COG3851	Histidine kinase
FDP11_02705	COG2197	response regulator
FDP11_02715	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDP11_02720	COG0583	DNA-binding transcription factor activity
FDP11_02730	COG0243	molybdopterin cofactor binding
FDP11_02760	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDP11_02775	COG1328	CTP reductase activity
FDP11_02815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDP11_02885	COG0602	queuosine metabolic process
FDP11_02895	COG0534	Mate efflux family protein
FDP11_02915	COG0189	ligase activity
FDP11_02915	COG4067	protein conserved in archaea
FDP11_02925	COG3111	PFAM Bacterial OB fold (BOF) protein
FDP11_02930	COG1492	cobalamin metabolic process
FDP11_02935	COG0725	ABC transporter, periplasmic molybdate-binding protein
FDP11_02940	COG4149	molybdate abc transporter
FDP11_02945	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FDP11_02955	COG5001	Diguanylate cyclase
FDP11_02955	COG4251	negative regulation of phosphorylation
FDP11_02955	COG3706	GGDEF domain
FDP11_02955	COG2203	Gaf domain
FDP11_02980	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FDP11_02985	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FDP11_03010	COG3140	Belongs to the UPF0181 family
FDP11_03015	COG0589	response to stress
FDP11_03025	COG0583	DNA-binding transcription factor activity
FDP11_03045	COG0023	Translation Initiation Factor
FDP11_03055	COG1181	Belongs to the D-alanine--D-alanine ligase family
FDP11_03065	COG0045	succinate-CoA ligase (ADP-forming) activity
FDP11_03065	COG1042	CoA-binding domain protein
FDP11_03065	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDP11_03070	COG0583	DNA-binding transcription factor activity
FDP11_03085	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDP11_03090	COG5002	protein histidine kinase activity
FDP11_03090	COG3447	MASE1 domain protein
FDP11_03090	COG5001	Diguanylate cyclase
FDP11_03095	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FDP11_03100	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FDP11_03105	COG1984	allophanate hydrolase subunit 2
FDP11_03115	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FDP11_03120	COG4181	ATPase activity
FDP11_03130	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FDP11_03135	COG5001	Diguanylate cyclase
FDP11_03135	COG3300	MHYT domain
FDP11_03145	COG0484	heat shock protein binding
FDP11_03170	COG4533	DNA binding
FDP11_03180	COG2050	protein possibly involved in aromatic compounds catabolism
FDP11_03195	COG2067	long-chain fatty acid transport protein
FDP11_03200	COG2267	carboxylic ester hydrolase activity
FDP11_03215	COG0861	Integral membrane protein TerC family
FDP11_03220	COG0737	Belongs to the 5'-nucleotidase family
FDP11_03225	COG3593	DNA synthesis involved in DNA repair
FDP11_03235	COG0583	DNA-binding transcription factor activity
FDP11_03240	COG2116	formate transmembrane transporter activity
FDP11_03245	COG2353	YceI-like domain
FDP11_03250	COG3038	cytochrome b561
FDP11_03265	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FDP11_03270	COG0513	Belongs to the DEAD box helicase family
FDP11_03275	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FDP11_03285	COG0840	transmembrane signaling receptor activity
FDP11_03295	COG0546	phosphoglycolate phosphatase activity
FDP11_03305	COG3437	response regulator, receiver
FDP11_03305	COG0784	Response regulator, receiver
FDP11_03325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDP11_03330	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FDP11_03335	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FDP11_03350	COG2207	Transcriptional regulator
FDP11_03355	COG1979	alcohol dehydrogenase
FDP11_03380	COG2271	Major facilitator Superfamily
FDP11_03385	COG0469	pyruvate kinase activity
FDP11_03390	COG1126	abc transporter atp-binding protein
FDP11_03395	COG0765	amino acid transport
FDP11_03400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDP11_03405	COG0765	amino acid transport
FDP11_03410	COG2200	EAL domain
FDP11_03410	COG2199	diguanylate cyclase activity
FDP11_03410	COG2203	Gaf domain
FDP11_03430	COG1609	Transcriptional regulator
FDP11_03435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP11_03435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP11_03440	COG1105	Belongs to the carbohydrate kinase PfkB family
FDP11_03445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDP11_03445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDP11_03445	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FDP11_03485	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FDP11_03490	COG0509	glycine decarboxylation via glycine cleavage system
FDP11_03495	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FDP11_03495	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FDP11_03545	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FDP11_03550	COG0583	DNA-binding transcription factor activity
FDP11_03555	COG2176	DNA-directed DNA polymerase activity
FDP11_03605	COG0242	peptide deformylase activity
FDP11_03645	COG2239	Acts as a magnesium transporter
FDP11_03665	COG0346	lactoylglutathione lyase activity
FDP11_03670	COG1902	pentaerythritol trinitrate reductase activity
FDP11_03690	COG5642	Protein of unknown function (DUF2384)
FDP11_03695	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FDP11_03715	COG4565	transcriptional regulatory protein
FDP11_03720	COG3290	protein histidine kinase activity
FDP11_03725	COG0471	metal ion transport
FDP11_03755	COG2076	Multidrug Resistance protein
FDP11_03775	COG1214	PFAM Peptidase M22, glycoprotease
FDP11_03775	COG0456	acetyltransferase
FDP11_03785	COG3069	C4-dicarboxylate transmembrane transporter activity
FDP11_03790	COG1704	LemA family
FDP11_03795	COG0501	Belongs to the peptidase M48B family
FDP11_03825	COG0641	radical SAM
FDP11_03845	COG3111	PFAM Bacterial OB fold (BOF) protein
FDP11_03850	COG1597	lipid kinase activity
FDP11_03855	COG0583	DNA-binding transcription factor activity
FDP11_03860	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDP11_03890	COG0714	Associated with various cellular activities
FDP11_03895	COG0641	radical SAM
FDP11_03900	COG3119	arylsulfatase activity
FDP11_03915	COG3119	arylsulfatase activity
FDP11_03920	COG3119	arylsulfatase activity
FDP11_03925	COG0745	RESPONSE REGULATOR receiver
FDP11_03940	COG2198	Histidine kinase
FDP11_03940	COG2205	protein histidine kinase activity
FDP11_03940	COG0784	Response regulator, receiver
FDP11_03945	COG1879	ABC-type sugar transport system periplasmic component
FDP11_03950	COG1803	Methylglyoxal synthase
FDP11_03955	COG0210	DNA helicase
FDP11_03960	COG1289	transmembrane transporter activity
FDP11_03995	COG1629	transport
FDP11_03995	COG4771	TonB-dependent receptor
FDP11_04010	COG0789	Transcriptional regulator
FDP11_04015	COG4604	ABC transporter, ATP-binding protein
FDP11_04020	COG4605	iron ion homeostasis
FDP11_04025	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDP11_04030	COG4607	ABC-type enterochelin transport system periplasmic component
FDP11_04040	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FDP11_04055	COG1609	Transcriptional regulator
FDP11_04060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDP11_04065	COG1879	ABC-type sugar transport system periplasmic component
FDP11_04070	COG1172	Belongs to the binding-protein-dependent transport system permease family
FDP11_04075	COG1129	ABC transporter
FDP11_04080	COG1869	D-ribose catabolic process
FDP11_04085	COG5001	Diguanylate cyclase
FDP11_04090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDP11_04150	COG0784	Response regulator, receiver
FDP11_04150	COG2205	protein histidine kinase activity
FDP11_04170	COG3300	MHYT domain
FDP11_04170	COG5001	Diguanylate cyclase
FDP11_04185	COG0330	HflC and HflK could
FDP11_04200	COG0517	IMP dehydrogenase activity
FDP11_04200	COG4175	Glycine betaine
FDP11_04205	COG4176	ABC-type proline glycine betaine transport system permease component
FDP11_04220	COG1012	belongs to the aldehyde dehydrogenase family
FDP11_04225	COG1309	transcriptional regulator
FDP11_04230	COG3706	GGDEF domain
FDP11_04240	COG1028	Short-chain dehydrogenase reductase Sdr
FDP11_04255	COG1024	Enoyl-CoA hydratase
FDP11_04260	COG1960	acyl-CoA dehydrogenase activity
FDP11_04270	COG0183	Belongs to the thiolase family
FDP11_04280	COG1960	acyl-CoA dehydrogenase activity
FDP11_04285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDP11_04305	COG4999	Histidine kinase
FDP11_04305	COG2205	protein histidine kinase activity
FDP11_04305	COG3437	response regulator, receiver
FDP11_04305	COG3850	Histidine kinase
FDP11_04320	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FDP11_04320	COG3264	Mechanosensitive ion channel
FDP11_04330	COG0110	maltose O-acetyltransferase activity
FDP11_04335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDP11_04340	COG1271	oxidase subunit
FDP11_04345	COG1294	oxidase, subunit
FDP11_04355	COG0384	phenazine biosynthesis protein PhzF
FDP11_04360	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDP11_04365	COG0789	Transcriptional regulator
FDP11_04445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDP11_04450	COG0516	GMP reductase activity
FDP11_04455	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FDP11_04455	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FDP11_04470	COG4989	oxidoreductase activity
FDP11_04485	COG0038	chloride channel
FDP11_04495	COG1914	H( )-stimulated, divalent metal cation uptake system
FDP11_04500	COG0302	gtp cyclohydrolase
FDP11_04510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FDP11_04530	COG2897	thiosulfate sulfurtransferase activity
FDP11_04560	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FDP11_04565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FDP11_04570	COG0840	transmembrane signaling receptor activity
FDP11_04580	COG2814	Major facilitator Superfamily
FDP11_04585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDP11_04600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDP11_04610	COG0840	transmembrane signaling receptor activity
FDP11_04630	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDP11_04645	COG2197	response regulator
FDP11_04650	COG3850	Histidine kinase
FDP11_04655	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDP11_04665	COG0243	molybdopterin cofactor binding
FDP11_04675	COG3005	denitrification pathway
FDP11_04695	COG0183	Belongs to the thiolase family
FDP11_04715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDP11_04720	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDP11_04750	COG1522	sequence-specific DNA binding
FDP11_04770	COG1566	PFAM secretion protein HlyD family protein
FDP11_04780	COG2205	protein histidine kinase activity
FDP11_04780	COG0784	Response regulator, receiver
FDP11_04785	COG1879	ABC-type sugar transport system periplasmic component
FDP11_04790	COG2827	Endonuclease containing a URI domain
FDP11_04795	COG3132	Protein of unknown function, DUF480
FDP11_04810	COG2926	Belongs to the UPF0265 family
FDP11_04815	COG0534	Mate efflux family protein
FDP11_04820	COG0673	inositol 2-dehydrogenase activity
FDP11_04825	COG5002	protein histidine kinase activity
FDP11_04825	COG2205	protein histidine kinase activity
FDP11_04825	COG0784	Response regulator, receiver
FDP11_04850	COG1522	sequence-specific DNA binding
FDP11_04860	COG0531	amino acid
FDP11_04875	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDP11_04880	COG2239	Acts as a magnesium transporter
FDP11_04890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FDP11_04895	COG0402	S-adenosylhomocysteine deaminase activity
FDP11_04905	COG1418	mRNA catabolic process
FDP11_04920	COG2814	Major facilitator Superfamily
FDP11_04930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDP11_04950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDP11_04970	COG4221	oxidoreductase activity
FDP11_04975	COG0745	RESPONSE REGULATOR receiver
FDP11_04980	COG2205	protein histidine kinase activity
FDP11_04990	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FDP11_04995	COG2194	sulfuric ester hydrolase activity
FDP11_05000	COG0673	inositol 2-dehydrogenase activity
FDP11_05010	COG2814	Major facilitator Superfamily
FDP11_05035	COG4667	esterase of the alpha-beta hydrolase superfamily
FDP11_05040	COG1741	Belongs to the pirin family
FDP11_05045	COG1278	Cold shock
FDP11_05065	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FDP11_05090	COG1686	Belongs to the peptidase S11 family
FDP11_05105	COG0625	glutathione transferase activity
FDP11_05115	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FDP11_05140	COG1028	Short-chain dehydrogenase reductase Sdr
FDP11_05155	COG3746	phosphate-selective porin O and P
FDP11_05175	COG2207	Transcriptional regulator
FDP11_05175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FDP11_05180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDP11_05210	COG0513	Belongs to the DEAD box helicase family
FDP11_05220	COG0583	DNA-binding transcription factor activity
FDP11_05235	COG1902	pentaerythritol trinitrate reductase activity
FDP11_05240	COG1063	alcohol dehydrogenase
FDP11_05250	COG1028	Short-chain dehydrogenase reductase Sdr
FDP11_05265	COG3122	Protein conserved in bacteria
FDP11_05280	COG0583	DNA-binding transcription factor activity
FDP11_05290	COG0252	asparaginase activity
FDP11_05295	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FDP11_05300	COG0574	Belongs to the PEP-utilizing enzyme family
FDP11_05300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FDP11_05320	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FDP11_05340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDP11_05360	COG3706	GGDEF domain
FDP11_05380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDP11_05410	COG3842	ATPase activity
FDP11_05470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDP11_05520	COG0583	DNA-binding transcription factor activity
FDP11_05530	COG4948	Mandelate Racemase Muconate Lactonizing
FDP11_05565	COG1342	Belongs to the UPF0251 family
FDP11_05575	COG3015	lipoprotein NlpE involved in copper resistance
FDP11_05585	COG3713	MltA-interacting MipA family protein
FDP11_05600	COG0583	DNA-binding transcription factor activity
FDP11_05630	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FDP11_05640	COG1335	isochorismatase
FDP11_05650	COG0753	catalase activity
FDP11_05660	COG1349	DNA-binding transcription factor activity
FDP11_05665	COG0346	lactoylglutathione lyase activity
FDP11_05680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDP11_05680	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP11_05680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDP11_05685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDP11_05690	COG3537	Alpha-1,2-mannosidase
FDP11_05695	COG3537	Alpha-1,2-mannosidase
FDP11_05705	COG3537	Alpha-1,2-mannosidase
FDP11_05710	COG3537	Alpha-1,2-mannosidase
FDP11_05715	COG2070	2-Nitropropane dioxygenase
FDP11_05720	COG0737	Belongs to the 5'-nucleotidase family
FDP11_05730	COG1309	transcriptional regulator
FDP11_05750	COG1280	lysine exporter protein (LysE YggA)
FDP11_05765	COG0459	protein refolding
FDP11_05770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FDP11_05780	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FDP11_05800	COG1304	FMN binding
FDP11_05830	COG1256	bacterial-type flagellum assembly
FDP11_05830	COG4786	Flagellar basal body rod
FDP11_05840	COG1706	bacterial-type flagellum-dependent cell motility
FDP11_05845	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FDP11_05850	COG4786	Flagellar basal body rod
FDP11_05855	COG4787	bacterial-type flagellum-dependent cell motility
FDP11_05860	COG1749	Flagellar hook protein flgE
FDP11_05865	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FDP11_05870	COG1558	bacterial-type flagellum-dependent cell motility
FDP11_05875	COG1815	bacterial-type flagellum-dependent cell motility
FDP11_05895	COG0741	lytic transglycosylase activity
FDP11_05900	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDP11_05920	COG1760	l-serine dehydratase
FDP11_05925	COG3104	oligopeptide transport
FDP11_05945	COG0583	DNA-binding transcription factor activity
FDP11_05960	COG2866	Carboxypeptidase
FDP11_05965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDP11_06000	COG3842	ATPase activity
FDP11_06010	COG1840	ABC-type Fe3 transport system, periplasmic component
FDP11_06025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDP11_06030	COG1609	Transcriptional regulator
FDP11_06060	COG3240	lipase activity
FDP11_06070	COG0577	efflux transmembrane transporter activity
FDP11_06070	COG1136	(ABC) transporter
FDP11_06075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDP11_06080	COG2067	long-chain fatty acid transport protein
FDP11_06085	COG3338	carbonate dehydratase activity
FDP11_06090	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FDP11_06105	COG1011	Hydrolase
FDP11_06145	COG0110	maltose O-acetyltransferase activity
FDP11_06150	COG1765	OsmC-like protein
FDP11_06155	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDP11_06155	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDP11_06170	COG3046	protein related to deoxyribodipyrimidine photolyase
FDP11_06175	COG0415	Belongs to the DNA photolyase family
FDP11_06180	COG3706	GGDEF domain
FDP11_06195	COG0840	transmembrane signaling receptor activity
FDP11_06200	COG3706	GGDEF domain
FDP11_06215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FDP11_06235	COG3033	Beta-eliminating lyase
FDP11_06245	COG0579	oxidoreductase
FDP11_06275	COG3706	GGDEF domain
FDP11_06320	COG0583	DNA-binding transcription factor activity
FDP11_06330	COG0189	ligase activity
FDP11_06335	COG0189	ligase activity
FDP11_06335	COG4067	protein conserved in archaea
FDP11_06345	COG1166	arginine decarboxylase activity
FDP11_06350	COG0010	Belongs to the arginase family
FDP11_06355	COG2814	Major facilitator Superfamily
FDP11_06360	COG1770	oligopeptidase
FDP11_06375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FDP11_06380	COG1121	(ABC) transporter
FDP11_06385	COG0803	Belongs to the bacterial solute-binding protein 9 family
FDP11_06425	COG0848	biopolymer transport protein
FDP11_06430	COG0811	peptide transport
FDP11_06435	COG0811	peptide transport
FDP11_06455	COG0745	RESPONSE REGULATOR receiver
FDP11_06460	COG0039	L-malate dehydrogenase activity
FDP11_06465	COG0584	glycerophosphoryl diester phosphodiesterase
FDP11_06475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FDP11_06535	COG1901	pseudouridine methyltransferase
FDP11_06540	COG0312	modulator of DNA gyrase
FDP11_06545	COG0312	modulator of DNA gyrase
FDP11_06555	COG0351	phosphomethylpyrimidine kinase
FDP11_06560	COG1116	anion transmembrane transporter activity
FDP11_06565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDP11_06570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDP11_06575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDP11_06580	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FDP11_06585	COG0352	thiamine-phosphate diphosphorylase activity
FDP11_06595	COG0243	molybdopterin cofactor binding
FDP11_06600	COG3005	denitrification pathway
FDP11_06610	COG1028	Short-chain dehydrogenase reductase Sdr
FDP11_06625	COG0456	acetyltransferase
FDP11_06645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDP11_06650	COG1929	Belongs to the glycerate kinase type-1 family
FDP11_06655	COG2610	gluconate transmembrane transporter activity
FDP11_06660	COG3835	regulator
FDP11_06685	COG0546	phosphoglycolate phosphatase activity
FDP11_06700	COG0583	DNA-binding transcription factor activity
FDP11_06710	COG0583	DNA-binding transcription factor activity
FDP11_06720	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FDP11_06725	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FDP11_06725	COG3408	Glycogen debranching enzyme
FDP11_06755	COG3047	cAMP biosynthetic process
FDP11_06760	COG1357	PFAM Pentapeptide repeats (8 copies)
FDP11_06790	COG2375	cellular response to nickel ion
FDP11_06795	COG0823	Involved in the tonB-independent uptake of proteins
FDP11_06800	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDP11_06820	COG0800	Aldolase
FDP11_06825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDP11_06840	COG1917	Cupin 2, conserved barrel domain protein
FDP11_06850	COG1028	Short-chain dehydrogenase reductase Sdr
FDP11_06855	COG1414	Transcriptional regulator
FDP11_06870	COG0583	DNA-binding transcription factor activity
FDP11_06875	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FDP11_06880	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FDP11_06895	COG2199	diguanylate cyclase activity
FDP11_06905	COG0561	phosphatase activity
FDP11_06910	COG0583	DNA-binding transcription factor activity
FDP11_06925	COG0564	pseudouridine synthase activity
FDP11_06930	COG0534	Mate efflux family protein
FDP11_06940	COG5001	Diguanylate cyclase
FDP11_06950	COG3123	guanosine phosphorylase activity
FDP11_06990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FDP11_07000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDP11_07005	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FDP11_07020	COG2259	Doxx family
FDP11_07025	COG1741	Belongs to the pirin family
FDP11_07045	COG0363	glucosamine-6-phosphate deaminase activity
FDP11_07060	COG0786	glutamate:sodium symporter activity
FDP11_07065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDP11_07070	COG1131	(ABC) transporter
FDP11_07080	COG0786	glutamate:sodium symporter activity
FDP11_07115	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FDP11_07125	COG3279	Response regulator of the LytR AlgR family
FDP11_07130	COG3275	phosphorelay sensor kinase activity
FDP11_07150	COG1136	(ABC) transporter
FDP11_07165	COG0772	Belongs to the SEDS family
FDP11_07170	COG0217	transcriptional regulatory protein
FDP11_07195	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDP11_07195	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FDP11_07205	COG0444	Belongs to the ABC transporter superfamily
FDP11_07210	COG4608	Belongs to the ABC transporter superfamily
FDP11_07235	COG1444	tRNA N-acetyltransferase activity
FDP11_07255	COG3340	Belongs to the peptidase S51 family
FDP11_07265	COG1263	PTS System
FDP11_07265	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDP11_07270	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FDP11_07290	COG4166	transmembrane transport
FDP11_07335	COG0259	pyridoxamine-phosphate oxidase activity
FDP11_07365	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDP11_07410	COG1132	(ABC) transporter
FDP11_07420	COG2207	Transcriptional regulator
FDP11_07445	COG0800	Aldolase
FDP11_07450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDP11_07455	COG1904	glucuronate isomerase
FDP11_07460	COG0246	Mannitol dehydrogenase
FDP11_07470	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FDP11_07480	COG2186	Transcriptional regulator
FDP11_07485	COG1312	Catalyzes the dehydration of D-mannonate
FDP11_07490	COG0513	Belongs to the DEAD box helicase family
FDP11_07495	COG2258	MOSC domain
FDP11_07510	COG1486	melibiose metabolic process
FDP11_07515	COG0583	DNA-binding transcription factor activity
FDP11_07535	COG1595	DNA-templated transcription, initiation
FDP11_07570	COG3634	alkyl hydroperoxide reductase activity
FDP11_07580	COG1846	Transcriptional regulator
FDP11_07585	COG1764	response to oxidative stress
FDP11_07610	COG2160	L-arabinose isomerase activity
FDP11_07620	COG1069	ribulokinase activity
FDP11_07625	COG1879	ABC-type sugar transport system periplasmic component
FDP11_07630	COG1129	ABC transporter
FDP11_07635	COG1172	Belongs to the binding-protein-dependent transport system permease family
FDP11_07660	COG0745	RESPONSE REGULATOR receiver
FDP11_07665	COG0642	Histidine kinase
FDP11_07670	COG1653	transport
FDP11_07675	COG0019	diaminopimelate decarboxylase activity
FDP11_07680	COG4264	IucA IucC family
FDP11_07685	COG2814	Major facilitator Superfamily
FDP11_07705	COG4772	TonB-dependent receptor
FDP11_07710	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FDP11_07715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDP11_07720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDP11_07725	COG1120	ATPase activity
FDP11_07730	COG0840	transmembrane signaling receptor activity
FDP11_07735	COG0612	Peptidase, M16
FDP11_07745	COG0739	heme binding
FDP11_07770	COG4580	involved in the transport of maltose and maltodextrins
FDP11_07795	COG2356	endonuclease I
FDP11_07815	COG1982	Orn Lys Arg decarboxylase major
FDP11_07820	COG0531	amino acid
FDP11_07830	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FDP11_07840	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FDP11_07845	COG1162	GTPase activity
FDP11_07850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDP11_07850	COG1263	PTS System
FDP11_07860	COG1999	signal sequence binding
FDP11_07875	COG2909	trisaccharide binding
FDP11_07890	COG0058	SHG alpha-glucan phosphorylase activity
FDP11_07895	COG1640	4-alpha-glucanotransferase
FDP11_07900	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FDP11_07905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDP11_07910	COG0366	Alpha amylase catalytic
FDP11_07925	COG3366	ferrous iron transmembrane transporter activity
FDP11_07930	COG0700	Nucleoside recognition
FDP11_07935	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FDP11_07940	COG3339	Conserved Protein
FDP11_07955	COG1301	dicarboxylic acid transport
FDP11_07965	COG0583	DNA-binding transcription factor activity
FDP11_07990	COG2095	MarC family integral membrane protein
FDP11_07995	COG4667	esterase of the alpha-beta hydrolase superfamily
FDP11_08000	COG3397	chitin binding
FDP11_08020	COG1686	Belongs to the peptidase S11 family
FDP11_08045	COG0583	DNA-binding transcription factor activity
FDP11_08050	COG4628	conserved protein (DUF2132)
FDP11_08060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDP11_08070	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDP11_08075	COG0628	permease
FDP11_08120	COG2814	Major facilitator Superfamily
FDP11_08135	COG0454	-acetyltransferase
FDP11_08145	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FDP11_08150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FDP11_08155	COG1882	Formate acetyltransferase
FDP11_08185	COG1360	Flagellar Motor Protein
FDP11_08190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FDP11_08195	COG1191	sigma factor activity
FDP11_08200	COG1580	Controls the rotational direction of flagella during chemotaxis
FDP11_08215	COG1516	flagellar protein fliS
FDP11_08220	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FDP11_08235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDP11_08250	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FDP11_08260	COG1987	bacterial-type flagellum assembly
FDP11_08340	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FDP11_08360	COG0346	lactoylglutathione lyase activity
FDP11_08395	COG0745	RESPONSE REGULATOR receiver
FDP11_08415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDP11_08425	COG0156	8-amino-7-oxononanoate synthase activity
FDP11_08430	COG1063	alcohol dehydrogenase
FDP11_08470	COG0668	transmembrane transport
FDP11_08480	COG1304	FMN binding
FDP11_08485	COG1620	l-lactate permease
FDP11_08490	COG0583	DNA-binding transcription factor activity
FDP11_08495	COG1505	serine-type exopeptidase activity
FDP11_08500	COG4172	Belongs to the ABC transporter superfamily
FDP11_08510	COG1067	ATP-dependent peptidase activity
FDP11_08540	COG1247	-acetyltransferase
FDP11_08545	COG0437	4 iron, 4 sulfur cluster binding
FDP11_08550	COG0348	domain, Protein
FDP11_08565	COG1122	ATPase activity
FDP11_08570	COG4720	Psort location CytoplasmicMembrane, score
FDP11_08575	COG1566	PFAM secretion protein HlyD family protein
FDP11_08585	COG3706	GGDEF domain
FDP11_08600	COG0813	purine-nucleoside phosphorylase activity
FDP11_08610	COG3272	Protein of unknown function (DUF1722)
FDP11_08615	COG0789	Transcriptional regulator
FDP11_08620	COG0415	Belongs to the DNA photolyase family
FDP11_08625	COG1376	ErfK ybiS ycfS ynhG family protein
FDP11_08625	COG1388	LysM domain
FDP11_08635	COG0513	Belongs to the DEAD box helicase family
FDP11_08640	COG1770	oligopeptidase
FDP11_08645	COG4771	TonB-dependent receptor
FDP11_08670	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FDP11_08675	COG1011	Hydrolase
FDP11_08680	COG3287	FIST C domain
FDP11_08680	COG2200	EAL domain
FDP11_08680	COG2199	diguanylate cyclase activity
FDP11_08700	COG0561	phosphatase activity
FDP11_08710	COG2267	carboxylic ester hydrolase activity
FDP11_08715	COG1280	lysine exporter protein (LysE YggA)
FDP11_08720	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FDP11_08725	COG0640	Transcriptional regulator
FDP11_08730	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDP11_08785	COG2095	MarC family integral membrane protein
FDP11_08795	COG0742	ribosomal rna small subunit methyltransferase
FDP11_08800	COG0552	protein localization to endoplasmic reticulum
FDP11_08805	COG2884	Cell division ATP-binding protein ftsE
FDP11_08810	COG2177	Part of the ABC transporter FtsEX involved in
FDP11_08825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FDP11_08830	COG0705	Rhomboid family
FDP11_08835	COG1580	Controls the rotational direction of flagella during chemotaxis
FDP11_08840	COG3161	chorismate lyase activity
FDP11_08845	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FDP11_08850	COG2937	Belongs to the GPAT DAPAT family
FDP11_08865	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FDP11_08870	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FDP11_08875	COG0534	Mate efflux family protein
FDP11_08880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDP11_08895	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FDP11_08900	COG4206	TonB-dependent receptor
FDP11_08910	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDP11_08940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDP11_08950	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FDP11_08985	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FDP11_08995	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FDP11_09000	COG0250	Participates in transcription elongation, termination and antitermination
FDP11_09005	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FDP11_09010	COG0081	regulation of translation
FDP11_09015	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FDP11_09020	COG0222	ribosome binding
FDP11_09025	COG0085	RNA polymerase activity
FDP11_09030	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FDP11_09035	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FDP11_09040	COG2816	NAD+ diphosphatase activity
FDP11_09055	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FDP11_09060	COG1573	uracil-dna glycosylase
FDP11_09065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDP11_09075	COG1253	flavin adenine dinucleotide binding
FDP11_09090	COG0151	Belongs to the GarS family
FDP11_09100	COG0138	bifunctional purine biosynthesis protein purh
FDP11_09110	COG0789	Transcriptional regulator
FDP11_09115	COG3710	Transcriptional regulator
FDP11_09125	COG0531	amino acid
FDP11_09130	COG1982	Orn Lys Arg decarboxylase major
FDP11_09225	COG3335	DDE superfamily endonuclease
FDP11_09235	COG3706	GGDEF domain
FDP11_09240	COG0488	(ABC) transporter
FDP11_09245	COG2814	Major facilitator Superfamily
FDP11_09250	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FDP11_09255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDP11_09260	COG2264	protein methyltransferase activity
FDP11_09270	COG0439	Biotin carboxylase
FDP11_09275	COG0511	ligase activity, forming carbon-carbon bonds
FDP11_09280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FDP11_09285	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDP11_09300	COG2814	Major facilitator Superfamily
FDP11_09305	COG0784	Response regulator, receiver
FDP11_09305	COG2205	protein histidine kinase activity
FDP11_09305	COG2198	Histidine kinase
FDP11_09330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDP11_09340	COG3263	regulation of cellular component size
FDP11_09350	COG4232	protein-disulfide reductase activity
FDP11_09355	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FDP11_09360	COG1027	Aspartate ammonia-lyase
FDP11_09365	COG3030	protein affecting phage T7 exclusion by the F plasmid
FDP11_09370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FDP11_09380	COG2205	protein histidine kinase activity
FDP11_09385	COG0745	RESPONSE REGULATOR receiver
FDP11_09395	COG3678	ATP-independent chaperone mediated protein folding
FDP11_09405	COG0205	6-phosphofructokinase activity
FDP11_09410	COG0534	Mate efflux family protein
FDP11_09420	COG0459	protein refolding
FDP11_09435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDP11_09445	COG1509	lysine 2,3-aminomutase activity
FDP11_09450	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FDP11_09460	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FDP11_09465	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FDP11_09470	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FDP11_09475	COG1053	succinate dehydrogenase
FDP11_09485	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FDP11_09505	COG4942	peptidase
FDP11_09510	COG1045	serine acetyltransferase
FDP11_09515	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FDP11_09520	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FDP11_09525	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FDP11_09530	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FDP11_09545	COG0471	metal ion transport
FDP11_09550	COG0688	phosphatidylethanolamine metabolic process
FDP11_09555	COG1162	GTPase activity
FDP11_09560	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FDP11_09630	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FDP11_09635	COG0802	atpase or kinase
FDP11_09645	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FDP11_09650	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FDP11_09660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FDP11_09665	COG0330	HflC and HflK could
FDP11_09670	COG0330	HflC and HflK could
FDP11_09675	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FDP11_09680	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FDP11_09690	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FDP11_09695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDP11_09695	COG1017	nitric oxide dioxygenase activity
FDP11_09700	COG1959	2 iron, 2 sulfur cluster binding
FDP11_09705	COG0557	exoribonuclease II activity
FDP11_09710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDP11_09715	COG0546	phosphoglycolate phosphatase activity
FDP11_09720	COG0180	Tryptophanyl-tRNA synthetase
FDP11_09750	COG0512	Glutamine amidotransferase of anthranilate synthase
FDP11_09755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDP11_09765	COG1012	belongs to the aldehyde dehydrogenase family
FDP11_09775	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDP11_09780	COG3954	Phosphoribulokinase
FDP11_09785	COG3089	Belongs to the UPF0270 family
FDP11_09790	COG0429	hydrolase of the alpha beta-hydrolase fold
FDP11_09800	COG0488	(ABC) transporter
FDP11_09810	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDP11_09825	COG1047	Peptidyl-prolyl cis-trans
FDP11_09835	COG1446	asparaginase
FDP11_09840	COG2900	Belongs to the SlyX family
FDP11_09850	COG0545	Peptidyl-prolyl cis-trans isomerase
FDP11_09855	COG2964	Protein conserved in bacteria
FDP11_09860	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FDP11_09865	COG2923	Belongs to the DsrF TusC family
FDP11_09870	COG2168	tRNA wobble position uridine thiolation
FDP11_09880	COG0049	tRNA binding
FDP11_09885	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FDP11_09890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FDP11_09895	COG2906	2 iron, 2 sulfur cluster binding
FDP11_09905	COG0281	malic enzyme
FDP11_09915	COG0626	cystathionine gamma-synthase activity
FDP11_09920	COG0527	aspartate kinase activity
FDP11_09920	COG0460	homoserine dehydrogenase
FDP11_09925	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FDP11_09935	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FDP11_09940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FDP11_09945	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FDP11_09950	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FDP11_09955	COG0137	argininosuccinate synthase activity
FDP11_09960	COG0165	Argininosuccinate lyase
FDP11_09960	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FDP11_09975	COG0678	peroxiredoxin activity
FDP11_09975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDP11_09985	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FDP11_10015	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FDP11_10020	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FDP11_10030	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FDP11_10035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FDP11_10040	COG0360	Binds together with S18 to 16S ribosomal RNA
FDP11_10045	COG2965	DNA replication, synthesis of RNA primer
FDP11_10055	COG0359	binds to the 23S rRNA
FDP11_10070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDP11_10120	COG3550	peptidyl-serine autophosphorylation
FDP11_10180	COG0166	Belongs to the GPI family
FDP11_10190	COG0735	belongs to the Fur family
FDP11_10200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDP11_10225	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FDP11_10230	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDP11_10235	COG0175	sulfate reduction
FDP11_10310	COG1410	methionine synthase
FDP11_10310	COG0646	methionine synthase
FDP11_10315	COG0527	aspartate kinase activity
FDP11_10325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FDP11_10335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FDP11_10350	COG0629	single-stranded DNA binding
FDP11_10355	COG2200	EAL domain
FDP11_10355	COG2199	diguanylate cyclase activity
FDP11_10380	COG3267	Type II secretory pathway component ExeA
FDP11_10380	COG3409	Peptidoglycan-binding domain 1 protein
FDP11_10390	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDP11_10395	COG1459	type II secretion system
FDP11_10440	COG1077	Cell shape determining protein MreB Mrl
FDP11_10445	COG1792	Involved in formation and maintenance of cell shape
FDP11_10450	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FDP11_10455	COG0424	maF-like protein
FDP11_10460	COG1530	ribonuclease E activity
FDP11_10465	COG3164	Protein of unknown function
FDP11_10470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDP11_10475	COG0312	modulator of DNA gyrase
FDP11_10480	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FDP11_10485	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FDP11_10500	COG0564	pseudouridine synthase activity
FDP11_10505	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FDP11_10510	COG3028	Belongs to the UPF0307 family
FDP11_10515	COG0312	modulator of DNA gyrase
FDP11_10520	COG2239	Acts as a magnesium transporter
FDP11_10525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP11_10530	COG1660	Displays ATPase and GTPase activities
FDP11_10535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP11_10540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FDP11_10550	COG1137	ATPase activity
FDP11_10555	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FDP11_10565	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FDP11_10565	COG0517	IMP dehydrogenase activity
FDP11_10575	COG1127	ABC transporter
FDP11_10580	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FDP11_10585	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FDP11_10590	COG2854	intermembrane phospholipid transfer
FDP11_10600	COG5007	Belongs to the BolA IbaG family
FDP11_10605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FDP11_10610	COG0204	Acyl-transferase
FDP11_10615	COG0251	oxidation-reduction process
FDP11_10620	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FDP11_10625	COG0540	Belongs to the ATCase OTCase family
FDP11_10635	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FDP11_10640	COG2235	arginine
FDP11_10670	COG0525	valine-tRNA ligase activity
FDP11_10675	COG2927	DNA polymerase III (CHI subunit)
FDP11_10680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FDP11_10685	COG0795	lipopolysaccharide-transporting ATPase activity
FDP11_10690	COG0795	lipopolysaccharide-transporting ATPase activity
FDP11_10705	COG1028	Short-chain dehydrogenase reductase Sdr
FDP11_10735	COG0726	polysaccharide deacetylase
FDP11_10740	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FDP11_10745	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FDP11_10750	COG1447	Phosphotransferase system cellobiose-specific component IIA
FDP11_10755	COG1486	melibiose metabolic process
FDP11_10760	COG3394	polysaccharide catabolic process
FDP11_10770	COG3437	response regulator, receiver
FDP11_10820	COG1012	belongs to the aldehyde dehydrogenase family
FDP11_10890	COG0741	lytic transglycosylase activity
FDP11_10895	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FDP11_10905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FDP11_10915	COG2066	Belongs to the glutaminase family
FDP11_10920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FDP11_10925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FDP11_10935	COG1872	DUF167
FDP11_10940	COG0762	integral membrane protein
FDP11_10945	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FDP11_10950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FDP11_10965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FDP11_10970	COG1678	Uncharacterized ACR, COG1678
FDP11_10975	COG0189	ligase activity
FDP11_10980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDP11_10985	COG2356	endonuclease I
FDP11_10990	COG3091	SprT-like family
FDP11_11000	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FDP11_11010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FDP11_11015	COG0583	DNA-binding transcription factor activity
FDP11_11020	COG4771	TonB-dependent receptor
FDP11_11025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDP11_11030	COG0126	phosphoglycerate kinase activity
FDP11_11035	COG0191	fructose-bisphosphate aldolase activity
FDP11_11040	COG0668	transmembrane transport
FDP11_11045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FDP11_11055	COG0583	DNA-binding transcription factor activity
FDP11_11065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDP11_11070	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FDP11_11075	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FDP11_11085	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FDP11_11095	COG3079	Belongs to the UPF0149 family
FDP11_11100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDP11_11105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDP11_11120	COG0354	folic acid binding
FDP11_11125	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FDP11_11135	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FDP11_11145	COG1595	DNA-templated transcription, initiation
FDP11_11150	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FDP11_11160	COG3086	response to oxidative stress
FDP11_11165	COG0481	GTPase activity
FDP11_11175	COG0571	ribonuclease III activity
FDP11_11180	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FDP11_11185	COG1381	Involved in DNA repair and RecF pathway recombination
FDP11_11190	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FDP11_11195	COG0736	holo-[acyl-carrier-protein] synthase activity
FDP11_11210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FDP11_11220	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDP11_11225	COG3956	TIGRFAM MazG family protein
FDP11_11230	COG0504	CTP synthase activity
FDP11_11235	COG0148	phosphopyruvate hydratase activity
FDP11_11240	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FDP11_11245	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FDP11_11250	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FDP11_11255	COG0585	pseudouridine synthase activity
FDP11_11260	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FDP11_11265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FDP11_11280	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FDP11_11285	COG1546	Belongs to the CinA family
FDP11_11290	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FDP11_11295	COG2137	regulation of response to DNA damage stimulus
FDP11_11300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FDP11_11305	COG0527	aspartate kinase activity
FDP11_11365	COG3630	sodium ion export across plasma membrane
FDP11_11370	COG5016	pyruvate
FDP11_11370	COG0511	ligase activity, forming carbon-carbon bonds
FDP11_11375	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FDP11_11380	COG1063	alcohol dehydrogenase
FDP11_11385	COG1238	metal cluster binding
FDP11_11390	COG0612	Peptidase, M16
FDP11_11395	COG2918	glutathione biosynthetic process
FDP11_11405	COG1854	S-ribosylhomocysteine lyase activity
FDP11_11410	COG4536	flavin adenine dinucleotide binding
FDP11_11415	COG4137	Cytochrome C assembly protein
FDP11_11420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDP11_11425	COG0228	four-way junction DNA binding
FDP11_11430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FDP11_11435	COG0336	Belongs to the RNA methyltransferase TrmD family
FDP11_11440	COG0335	large ribosomal subunit rRNA binding
FDP11_11445	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FDP11_11450	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FDP11_11455	COG0237	dephospho-CoA kinase activity
FDP11_11465	COG1459	type II secretion system
FDP11_11470	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDP11_11480	COG0157	Belongs to the NadC ModD family
FDP11_11490	COG2186	Transcriptional regulator
FDP11_11495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FDP11_11500	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDP11_11505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDP11_11520	COG0288	reversible hydration of carbon dioxide
FDP11_11525	COG0659	secondary active sulfate transmembrane transporter activity
FDP11_11535	COG1131	(ABC) transporter
FDP11_11540	COG0842	Transport permease protein
FDP11_11550	COG1560	Kdo2-lipid A biosynthetic process
FDP11_11560	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FDP11_11565	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FDP11_11570	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDP11_11585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDP11_11600	COG1489	DNA binding
FDP11_11605	COG1643	Atp-dependent helicase
FDP11_11610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDP11_11615	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDP11_11620	COG1049	propionate catabolic process, 2-methylcitrate cycle
FDP11_11625	COG3112	Uncharacterised protein family (UPF0231)
FDP11_11635	COG0004	ammonium transporteR
FDP11_11640	COG1840	ABC-type Fe3 transport system, periplasmic component
FDP11_11650	COG3842	ATPase activity
FDP11_11655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDP11_11670	COG2971	BadF BadG BcrA BcrD
FDP11_11680	COG4608	Belongs to the ABC transporter superfamily
FDP11_11685	COG0444	Belongs to the ABC transporter superfamily
FDP11_11690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDP11_11700	COG0747	negative chemotaxis
FDP11_11705	COG2205	protein histidine kinase activity
FDP11_11705	COG0784	Response regulator, receiver
FDP11_11705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDP11_11705	COG2198	Histidine kinase
FDP11_11715	COG2813	Specifically methylates the guanine in position
FDP11_11720	COG0628	permease
FDP11_11725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FDP11_11730	COG0316	Belongs to the HesB IscA family
FDP11_11740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDP11_11745	COG0739	heme binding
FDP11_11750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FDP11_11755	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FDP11_11760	COG0047	phosphoribosylformylglycinamidine synthase activity
FDP11_11760	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FDP11_11785	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDP11_11790	COG2252	PERMEase
FDP11_11795	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FDP11_11810	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FDP11_11815	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FDP11_11820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FDP11_11825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDP11_11825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDP11_11845	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FDP11_11850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FDP11_11855	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FDP11_11860	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FDP11_11865	COG0142	geranyltranstransferase activity
FDP11_11870	COG1722	exodeoxyribonuclease VII activity
FDP11_11875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FDP11_11880	COG2885	chlorophyll binding
FDP11_11885	COG0301	tRNA thio-modification
FDP11_11885	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FDP11_11890	COG0583	DNA-binding transcription factor activity
FDP11_11900	COG2363	Small membrane protein
FDP11_11905	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FDP11_11915	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FDP11_11920	COG1611	Belongs to the LOG family
FDP11_11935	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FDP11_11935	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FDP11_11945	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FDP11_11950	COG1464	Belongs to the NlpA lipoprotein family
FDP11_11955	COG2011	ABC-type metal ion transport system permease component
FDP11_11960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDP11_11970	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FDP11_11980	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDP11_11980	COG1263	PTS System
FDP11_11985	COG0366	Alpha amylase catalytic
FDP11_12000	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FDP11_12005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FDP11_12010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDP11_12015	COG0321	lipoyl(octanoyl) transferase activity
FDP11_12020	COG2921	Belongs to the UPF0250 family
FDP11_12025	COG1686	Belongs to the peptidase S11 family
FDP11_12030	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FDP11_12035	COG0772	Belongs to the SEDS family
FDP11_12040	COG0768	penicillin binding
FDP11_12045	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FDP11_12050	COG0799	negative regulation of ribosome biogenesis
FDP11_12055	COG1466	dna polymerase III delta subunit
FDP11_12060	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FDP11_12065	COG0495	leucyl-tRNA aminoacylation
FDP11_12070	COG2888	peptidyl-tyrosine sulfation
FDP11_12075	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FDP11_12080	COG4535	Mg2 and Co2 transporter CorC
FDP11_12085	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FDP11_12090	COG1702	phosphate starvation-inducible protein PhoH
FDP11_12095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FDP11_12105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDP11_12220	COG0012	GTP binding
FDP11_12225	COG0193	aminoacyl-tRNA hydrolase activity
FDP11_12230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDP11_12235	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FDP11_12240	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FDP11_12245	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FDP11_12250	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FDP11_12255	COG2890	protein-(glutamine-N5) methyltransferase activity
FDP11_12260	COG3094	Invasion gene expression up-regulator, SirB
FDP11_12265	COG2912	Transglutaminase-like superfamily
FDP11_12270	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FDP11_12275	COG0737	Belongs to the 5'-nucleotidase family
FDP11_12285	COG1187	pseudouridine synthase activity
FDP11_12290	COG2840	Smr protein MutS2
FDP11_12330	COG2217	Heavy metal translocating P-type atpase
FDP11_12330	COG2608	mercury ion transmembrane transporter activity
FDP11_12345	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDP11_12350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDP11_12410	COG0784	Response regulator, receiver
FDP11_12410	COG0835	chemotaxis
FDP11_12415	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FDP11_12420	COG1815	bacterial-type flagellum-dependent cell motility
FDP11_12425	COG1558	bacterial-type flagellum-dependent cell motility
FDP11_12445	COG4787	bacterial-type flagellum-dependent cell motility
FDP11_12455	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FDP11_12460	COG1706	bacterial-type flagellum-dependent cell motility
FDP11_12465	COG3951	Flagellar rod assembly protein muramidase FlgJ
FDP11_12465	COG1705	Flagellar rod assembly protein muramidase FlgJ
FDP11_12475	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDP11_12485	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDP11_12495	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDP11_12500	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDP11_12510	COG2190	(PTS) system
FDP11_12515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FDP11_12520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP11_12530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FDP11_12535	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FDP11_12540	COG3115	cell septum assembly
FDP11_12545	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FDP11_12575	COG0330	HflC and HflK could
FDP11_12580	COG2194	sulfuric ester hydrolase activity
FDP11_12600	COG1215	transferase activity, transferring glycosyl groups
FDP11_12605	COG1215	transferase activity, transferring glycosyl groups
FDP11_12610	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FDP11_12615	COG3118	belongs to the thioredoxin family
FDP11_12615	COG0457	Tetratricopeptide repeat
FDP11_12620	COG3118	belongs to the thioredoxin family
FDP11_12630	COG0300	oxidoreductase activity
FDP11_12635	COG1090	epimerase
FDP11_12665	COG0622	Phosphoesterase
FDP11_12685	COG3710	Transcriptional regulator
FDP11_12690	COG0326	Molecular chaperone. Has ATPase activity
FDP11_12695	COG0563	adenylate kinase activity
FDP11_12700	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FDP11_12705	COG3104	oligopeptide transport
FDP11_12710	COG0250	Participates in transcription elongation, termination and antitermination
FDP11_12715	COG0367	asparagine synthase
FDP11_12720	COG4651	solute:proton antiporter activity
FDP11_12720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDP11_12725	COG1940	carbohydrate kinase activity
FDP11_12725	COG1846	Transcriptional regulator
FDP11_12730	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FDP11_12740	COG1263	PTS System
FDP11_12740	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDP11_12745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDP11_12750	COG0735	belongs to the Fur family
FDP11_12770	COG0596	Alpha beta hydrolase
FDP11_12775	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FDP11_12780	COG0033	Phosphoglucomutase
FDP11_12790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDP11_12805	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FDP11_12810	COG1053	succinate dehydrogenase
FDP11_12815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FDP11_12820	COG0567	Dehydrogenase, E1 component
FDP11_12825	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDP11_12830	COG0045	succinate-CoA ligase (ADP-forming) activity
FDP11_12840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FDP11_12845	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FDP11_12850	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FDP11_12855	COG2233	PERMEase
FDP11_12875	COG4783	chaperone-mediated protein folding
FDP11_12890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FDP11_12895	COG2716	regulation of RNA biosynthetic process
FDP11_12900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDP11_12920	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FDP11_12925	COG1393	Belongs to the ArsC family
FDP11_12955	COG2837	iron assimilation
FDP11_12960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDP11_12970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDP11_12975	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FDP11_12980	COG1334	flagellar protein FlaG
FDP11_12985	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FDP11_12995	COG1516	flagellar protein fliS
FDP11_13005	COG4191	Histidine kinase
FDP11_13015	COG1677	Flagellar hook-basal body complex protein FliE
FDP11_13025	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FDP11_13075	COG1987	bacterial-type flagellum assembly
FDP11_13080	COG1684	flagellar biosynthetic protein fliR
FDP11_13115	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FDP11_13120	COG0784	Response regulator, receiver
FDP11_13120	COG0643	Histidine kinase
FDP11_13120	COG2198	Histidine kinase
FDP11_13125	COG2201	protein-glutamate methylesterase activity
FDP11_13130	COG1192	Involved in chromosome partitioning
FDP11_13140	COG0835	chemotaxis
FDP11_13150	COG4133	protoheme IX ABC transporter activity
FDP11_13155	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FDP11_13160	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FDP11_13165	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FDP11_13170	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FDP11_13175	COG1138	Cytochrome C-type biogenesis protein
FDP11_13180	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FDP11_13195	COG2853	Lipoprotein
FDP11_13205	COG2067	long-chain fatty acid transport protein
FDP11_13225	COG0183	Belongs to the thiolase family
FDP11_13230	COG1024	Enoyl-CoA hydratase
FDP11_13230	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDP11_13245	COG2062	phosphohistidine phosphatase, SixA
FDP11_13250	COG2840	Smr protein MutS2
FDP11_13255	COG2890	protein-(glutamine-N5) methyltransferase activity
FDP11_13260	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FDP11_13265	COG2860	membrane
FDP11_13275	COG3101	peptidyl-lysine hydroxylation
FDP11_13290	COG0431	NADPH-dependent FMN reductase
FDP11_13295	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDP11_13295	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FDP11_13300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FDP11_13310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDP11_13315	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FDP11_13325	COG0101	tRNA pseudouridine synthase activity
FDP11_13330	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FDP11_13335	COG0285	dihydrofolate synthase activity
FDP11_13340	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FDP11_13345	COG1286	toxin biosynthetic process
FDP11_13350	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FDP11_13355	COG0583	DNA-binding transcription factor activity
FDP11_13360	COG0745	RESPONSE REGULATOR receiver
FDP11_13370	COG2832	Protein of unknown function (DUF454)
FDP11_13375	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FDP11_13385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FDP11_13390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FDP11_13395	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FDP11_13400	COG0814	amino acid
FDP11_13405	COG0251	oxidation-reduction process
FDP11_13410	COG3681	Belongs to the UPF0597 family
FDP11_13425	COG2261	transglycosylase associated protein
FDP11_13430	COG2983	Belongs to the UPF0260 family
FDP11_13435	COG0668	transmembrane transport
FDP11_13440	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FDP11_13445	COG0346	lactoylglutathione lyase activity
FDP11_13455	COG1785	Belongs to the alkaline phosphatase family
FDP11_13475	COG2226	methyltransferase
FDP11_13490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDP11_13495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDP11_13505	COG3139	Protein of unknown function (DUF1315)
FDP11_13510	COG0252	asparaginase activity
FDP11_13515	COG0616	signal peptide processing
FDP11_13520	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDP11_13520	COG1902	pentaerythritol trinitrate reductase activity
FDP11_13525	COG0778	Nitroreductase
FDP11_13530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FDP11_13550	COG0123	including yeast histone deacetylase and acetoin utilization protein
FDP11_13560	COG3083	sulfuric ester hydrolase activity
FDP11_13565	COG3082	Protein of unknown function (DUF1414)
FDP11_13570	COG3081	Nucleoid-associated protein
FDP11_13585	COG1757	Na H antiporter
FDP11_13590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FDP11_13595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDP11_13600	COG2095	MarC family integral membrane protein
FDP11_13605	COG1454	alcohol dehydrogenase
FDP11_13605	COG1012	belongs to the aldehyde dehydrogenase family
FDP11_13625	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FDP11_13635	COG2056	Na+-H+ antiporter family
FDP11_13640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDP11_13655	COG2885	chlorophyll binding
FDP11_13665	COG0346	lactoylglutathione lyase activity
FDP11_13670	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FDP11_13675	COG4660	Part of a membrane complex involved in electron transport
FDP11_13680	COG4659	FMN binding
FDP11_13685	COG4658	electron transport chain
FDP11_13690	COG4656	Part of a membrane complex involved in electron transport
FDP11_13695	COG2878	Part of a membrane complex involved in electron transport
FDP11_13700	COG4657	Part of a membrane complex involved in electron transport
FDP11_13715	COG0708	Exodeoxyribonuclease III
FDP11_13725	COG3923	Primosomal replication protein n
FDP11_13730	COG0730	response to heat
FDP11_13735	COG1199	ATP-dependent helicase activity
FDP11_13745	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDP11_13750	COG1187	pseudouridine synthase activity
FDP11_13760	COG1278	Cold shock
FDP11_13765	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FDP11_13770	COG0542	response to heat
FDP11_13780	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FDP11_13785	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FDP11_13790	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FDP11_13800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FDP11_13810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FDP11_13815	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FDP11_13820	COG0297	glycogen (starch) synthase activity
FDP11_13840	COG3070	regulator of competence-specific genes
FDP11_13845	COG1609	Transcriptional regulator
FDP11_13850	COG3381	protein complex oligomerization
FDP11_13855	COG0745	RESPONSE REGULATOR receiver
FDP11_13860	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FDP11_13865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FDP11_13870	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FDP11_13875	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FDP11_13880	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FDP11_13900	COG4067	protein conserved in archaea
FDP11_13900	COG0189	ligase activity
FDP11_13910	COG0500	methyltransferase
FDP11_13915	COG4106	trans-aconitate 2-methyltransferase activity
FDP11_13920	COG1801	Protein of unknown function DUF72
FDP11_13925	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FDP11_13930	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FDP11_13935	COG0840	transmembrane signaling receptor activity
FDP11_13940	COG0632	four-way junction helicase activity
FDP11_13945	COG2255	four-way junction helicase activity
FDP11_13950	COG1271	oxidase subunit
FDP11_13955	COG1294	oxidase, subunit
FDP11_13960	COG4890	Cyd operon protein YbgT
FDP11_13970	COG0824	Thioesterase
FDP11_13975	COG0811	peptide transport
FDP11_13990	COG0823	Involved in the tonB-independent uptake of proteins
FDP11_13995	COG2885	chlorophyll binding
FDP11_14000	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FDP11_14005	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDP11_14010	COG0653	protein targeting
FDP11_14015	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FDP11_14020	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDP11_14025	COG2186	Transcriptional regulator
FDP11_14035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDP11_14035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDP11_14040	COG0489	protein tyrosine kinase activity
FDP11_14045	COG0572	uridine kinase
FDP11_14055	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FDP11_14060	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FDP11_14065	COG0659	secondary active sulfate transmembrane transporter activity
FDP11_14075	COG1530	ribonuclease E activity
FDP11_14090	COG0564	pseudouridine synthase activity
FDP11_14095	COG0424	maF-like protein
FDP11_14100	COG1399	metal-binding, possibly nucleic acid-binding protein
FDP11_14110	COG0416	fatty acid biosynthetic process
FDP11_14115	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FDP11_14145	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FDP11_14150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FDP11_14160	COG0084	hydrolase, TatD family'
FDP11_14165	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FDP11_14165	COG1263	PTS System
FDP11_14185	COG0733	neurotransmitter:sodium symporter activity
FDP11_14200	COG4667	esterase of the alpha-beta hydrolase superfamily
FDP11_14205	COG0469	pyruvate kinase activity
FDP11_14210	COG1940	carbohydrate kinase activity
FDP11_14215	COG0835	chemotaxis
FDP11_14215	COG0784	Response regulator, receiver
FDP11_14220	COG0587	DNA-directed DNA polymerase activity
FDP11_14235	COG1028	Short-chain dehydrogenase reductase Sdr
FDP11_14240	COG0616	signal peptide processing
FDP11_14245	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FDP11_14250	COG0539	negative regulation of cytoplasmic translation
FDP11_14260	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FDP11_14265	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FDP11_14270	COG0284	orotidine-5'-phosphate decarboxylase activity
FDP11_14275	COG4166	transmembrane transport
FDP11_14300	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FDP11_14310	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FDP11_14310	COG3008	intermembrane lipid transfer
FDP11_14315	COG2995	paraquat-inducible protein a
FDP11_14320	COG3258	Cytochrome c
FDP11_14325	COG2863	cytochrome
FDP11_14365	COG4232	protein-disulfide reductase activity
FDP11_14370	COG3118	belongs to the thioredoxin family
FDP11_14400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDP11_14410	COG1136	(ABC) transporter
FDP11_14410	COG0577	efflux transmembrane transporter activity
FDP11_14415	COG1136	(ABC) transporter
FDP11_14415	COG0577	efflux transmembrane transporter activity
FDP11_14420	COG0577	efflux transmembrane transporter activity
FDP11_14420	COG1136	(ABC) transporter
FDP11_14425	COG1335	isochorismatase
FDP11_14445	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FDP11_14470	COG2116	formate transmembrane transporter activity
FDP11_14480	COG0390	transport system, permease component
FDP11_14485	COG4459	periplasmic nitrate reductase
FDP11_14490	COG3005	denitrification pathway
FDP11_14495	COG0243	molybdopterin cofactor binding
FDP11_14510	COG1227	inorganic diphosphatase activity
FDP11_14520	COG4172	Belongs to the ABC transporter superfamily
FDP11_14530	COG4171	peptide transport system, permease
FDP11_14545	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FDP11_14550	COG1842	Phage shock protein A
FDP11_14560	COG1983	PspC domain protein
FDP11_14565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDP11_14580	COG2818	Glycosylase
FDP11_14585	COG5380	lipid catabolic process
FDP11_14590	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FDP11_14595	COG0626	cystathionine gamma-synthase activity
FDP11_14605	COG0733	neurotransmitter:sodium symporter activity
FDP11_14615	COG0564	pseudouridine synthase activity
FDP11_14625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDP11_14630	COG1151	hydroxylamine reductase activity
FDP11_14635	COG3604	Transcriptional regulator
FDP11_14650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FDP11_14655	COG4136	ATPase activity
FDP11_14660	COG4135	transport system, permease component
FDP11_14665	COG4134	Bacterial extracellular solute-binding protein
FDP11_14670	COG0398	Pfam SNARE associated Golgi protein
FDP11_14680	COG0493	'glutamate synthase
FDP11_14705	COG3313	Fe-S protein
FDP11_14735	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FDP11_14740	COG2205	protein histidine kinase activity
FDP11_14745	COG0745	RESPONSE REGULATOR receiver
FDP11_14755	COG1061	Type III restriction enzyme res subunit
FDP11_14760	COG1187	pseudouridine synthase activity
FDP11_14765	COG2814	Major facilitator Superfamily
FDP11_14795	COG3005	denitrification pathway
FDP11_14800	COG0702	epimerase
FDP11_14805	COG0534	Mate efflux family protein
FDP11_14810	COG4181	ATPase activity
FDP11_14825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDP11_14840	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FDP11_14845	COG3273	potassium ion transport
FDP11_14845	COG2985	domain, Protein
FDP11_14850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDP11_14865	COG1737	Transcriptional regulator
FDP11_14870	COG0076	glutamate decarboxylase activity
FDP11_14880	COG2431	L-lysine efflux transmembrane transporter activity
FDP11_14900	COG3070	regulator of competence-specific genes
FDP11_14915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDP11_14915	COG4191	Histidine kinase
FDP11_14925	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FDP11_14930	COG3048	D-serine ammonia-lyase activity
FDP11_14935	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FDP11_14940	COG4988	ABC transporter
FDP11_14945	COG0492	ferredoxin-NADP+ reductase activity
FDP11_14970	COG0471	metal ion transport
FDP11_14975	COG2949	membrane
FDP11_14980	COG0281	malic enzyme
FDP11_14985	COG1643	Atp-dependent helicase
FDP11_14990	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FDP11_15005	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FDP11_15040	COG0247	lactate metabolic process
FDP11_15040	COG0277	FAD linked oxidase domain protein
FDP11_15055	COG2986	histidine ammonia-lyase
FDP11_15060	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FDP11_15065	COG0010	Belongs to the arginase family
FDP11_15070	COG1228	amidohydrolase
FDP11_15075	COG2188	Transcriptional regulator
FDP11_15090	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FDP11_15100	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FDP11_15110	COG0393	Putative heavy-metal-binding
FDP11_15140	COG3706	GGDEF domain
FDP11_15145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FDP11_15150	COG0072	phenylalanine-tRNA ligase activity
FDP11_15150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDP11_15165	COG0776	regulation of translation
FDP11_15175	COG0500	methyltransferase
FDP11_15180	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FDP11_15185	COG0295	cytidine deaminase activity
FDP11_15190	COG1346	cytolysis
FDP11_15195	COG1380	Effector of murein hydrolase LrgA
FDP11_15200	COG2925	Exonuclease
FDP11_15210	COG0702	epimerase
FDP11_15215	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FDP11_15220	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FDP11_15245	COG2988	succinylglutamate desuccinylase activity
FDP11_15250	COG4139	cobalamin transport
FDP11_15255	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FDP11_15275	COG0583	DNA-binding transcription factor activity
FDP11_15285	COG1451	nucleotide metabolic process
FDP11_15290	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FDP11_15320	COG3938	Belongs to the proline racemase family
FDP11_15340	COG2423	ornithine cyclodeaminase activity
FDP11_15345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDP11_15350	COG3842	ATPase activity
FDP11_15355	COG1176	ABC-type spermidine putrescine transport system, permease component I
FDP11_15360	COG1177	transmembrane transport
FDP11_15375	COG3291	Pkd domain containing protein
FDP11_15395	COG0444	Belongs to the ABC transporter superfamily
FDP11_15400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDP11_15405	COG0601	transmembrane transport
FDP11_15415	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDP11_15430	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FDP11_15440	COG0625	glutathione transferase activity
FDP11_15550	COG1278	Cold shock
FDP11_15555	COG0557	exoribonuclease II activity
FDP11_15595	COG1475	DNA binding
FDP11_15605	COG1783	phage Terminase large subunit
FDP11_15755	COG1280	lysine exporter protein (LysE YggA)
FDP11_15800	COG1280	lysine exporter protein (LysE YggA)
FDP11_15825	COG1757	Na H antiporter
FDP11_15830	COG0174	glutamine synthetase
FDP11_15840	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FDP11_15845	COG1396	sequence-specific DNA binding
FDP11_15845	COG1917	Cupin 2, conserved barrel domain protein
FDP11_15850	COG1012	belongs to the aldehyde dehydrogenase family
FDP11_15855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDP11_15865	COG2957	Belongs to the agmatine deiminase family
FDP11_15870	COG1012	belongs to the aldehyde dehydrogenase family
FDP11_15875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDP11_15880	COG1227	inorganic diphosphatase activity
FDP11_15890	COG2771	luxR family
FDP11_15890	COG2200	EAL domain
FDP11_15905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FDP11_15920	COG1846	Transcriptional regulator
FDP11_15925	COG2315	Protein conserved in bacteria
FDP11_15945	COG0110	maltose O-acetyltransferase activity
FDP11_15975	COG3063	Type IV pilus biogenesis stability protein PilW
FDP11_15980	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FDP11_15995	COG0531	amino acid
FDP11_16005	COG1560	Kdo2-lipid A biosynthetic process
FDP11_16010	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FDP11_16015	COG1280	lysine exporter protein (LysE YggA)
FDP11_16025	COG1115	amino acid carrier protein
FDP11_16050	COG1368	sulfuric ester hydrolase activity
FDP11_16055	COG0642	Histidine kinase
FDP11_16060	COG0745	RESPONSE REGULATOR receiver
FDP11_16070	COG1028	Short-chain dehydrogenase reductase Sdr
FDP11_16090	COG2113	Glycine betaine
FDP11_16095	COG4176	ABC-type proline glycine betaine transport system permease component
FDP11_16115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDP11_16120	COG0456	acetyltransferase
FDP11_16125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDP11_16130	COG0662	Cupin 2, conserved barrel domain protein
FDP11_16135	COG0527	aspartate kinase activity
FDP11_16155	COG1858	cytochrome C peroxidase
FDP11_16170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDP11_16185	COG3290	protein histidine kinase activity
FDP11_16190	COG4565	transcriptional regulatory protein
FDP11_16195	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FDP11_16200	COG0363	glucosamine-6-phosphate deaminase activity
FDP11_16205	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FDP11_16230	COG3284	Transcriptional regulator
FDP11_16235	COG1012	belongs to the aldehyde dehydrogenase family
FDP11_16305	COG4669	(LipO)protein
FDP11_16325	COG3177	Filamentation induced by cAMP protein fic
FDP11_16365	COG1073	alpha beta
FDP11_16370	COG1073	alpha beta
FDP11_16380	COG4792	protein secretion
FDP11_16385	COG4791	protein targeting
FDP11_16390	COG4794	Type iii secretion
FDP11_16395	COG4790	Type iii secretion
FDP11_16465	COG0457	Tetratricopeptide repeat
FDP11_16485	COG0730	response to heat
FDP11_16515	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FDP11_16520	COG0372	Belongs to the citrate synthase family
FDP11_16530	COG2828	Protein conserved in bacteria
FDP11_16555	COG0561	phosphatase activity
FDP11_16560	COG0602	queuosine metabolic process
FDP11_16565	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FDP11_16570	COG3706	GGDEF domain
FDP11_16610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FDP11_16615	COG0840	transmembrane signaling receptor activity
FDP11_16620	COG1254	Belongs to the acylphosphatase family
FDP11_16625	COG2920	part of a sulfur-relay system
FDP11_16635	COG0670	Belongs to the BI1 family
FDP11_16640	COG1126	abc transporter atp-binding protein
FDP11_16645	COG0765	amino acid transport
FDP11_16650	COG4597	amino acid ABC transporter
FDP11_16655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDP11_16675	COG1666	GTP binding
FDP11_16680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDP11_16700	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FDP11_16700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FDP11_16710	COG3008	intermembrane lipid transfer
FDP11_16715	COG2995	paraquat-inducible protein a
FDP11_16720	COG1132	(ABC) transporter
FDP11_16725	COG1956	GAF domain-containing protein
FDP11_16730	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FDP11_16745	COG0308	aminopeptidase N
FDP11_16755	COG2902	Dehydrogenase
FDP11_16760	COG0167	dihydroorotate dehydrogenase activity
FDP11_16775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FDP11_16775	COG0116	Belongs to the methyltransferase superfamily
FDP11_16800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FDP11_16805	COG1067	ATP-dependent peptidase activity
FDP11_16810	COG3120	sequence-specific DNA binding
FDP11_16860	COG2205	protein histidine kinase activity
FDP11_16860	COG0784	Response regulator, receiver
FDP11_16875	COG3278	Belongs to the heme-copper respiratory oxidase family
FDP11_16890	COG2010	Cytochrome c
FDP11_16900	COG2217	Heavy metal translocating P-type atpase
FDP11_16915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDP11_16920	COG0589	response to stress
FDP11_16930	COG0037	tRNA processing
FDP11_16950	COG3842	ATPase activity
FDP11_16960	COG1177	transmembrane transport
FDP11_16970	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FDP11_16975	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FDP11_16985	COG0004	ammonium transporteR
FDP11_17050	COG0437	4 iron, 4 sulfur cluster binding
FDP11_17055	COG3383	formate dehydrogenase (NAD+) activity
FDP11_17055	COG0243	molybdopterin cofactor binding
FDP11_17065	COG3381	protein complex oligomerization
FDP11_17090	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDP11_17095	COG0488	(ABC) transporter
FDP11_17105	COG4191	Histidine kinase
FDP11_17110	COG2204	response regulator
FDP11_17130	COG3842	ATPase activity
FDP11_17135	COG0746	molybdenum cofactor guanylyltransferase activity
FDP11_17155	COG0438	transferase activity, transferring glycosyl groups
FDP11_17160	COG1215	transferase activity, transferring glycosyl groups
FDP11_17165	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FDP11_17175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDP11_17190	COG1643	Atp-dependent helicase
FDP11_17195	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FDP11_17205	COG3381	protein complex oligomerization
FDP11_17210	COG3302	dmso reductase anchor subunit
FDP11_17215	COG0437	4 iron, 4 sulfur cluster binding
FDP11_17220	COG0243	molybdopterin cofactor binding
FDP11_17250	COG3706	GGDEF domain
FDP11_17260	COG0443	Heat shock 70 kDa protein
FDP11_17265	COG0443	Heat shock 70 kDa protein
FDP11_17295	COG1132	(ABC) transporter
FDP11_17300	COG1132	(ABC) transporter
FDP11_17325	COG0814	amino acid
FDP11_17340	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FDP11_17350	COG0861	Integral membrane protein TerC family
FDP11_17360	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FDP11_17365	COG1328	CTP reductase activity
FDP11_17370	COG1280	lysine exporter protein (LysE YggA)
FDP11_17380	COG3300	MHYT domain
FDP11_17380	COG5001	Diguanylate cyclase
FDP11_17390	COG4191	Histidine kinase
FDP11_17390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDP11_17395	COG0471	metal ion transport
FDP11_17425	COG1940	carbohydrate kinase activity
FDP11_17465	COG0840	transmembrane signaling receptor activity
FDP11_17465	COG3290	protein histidine kinase activity
FDP11_17470	COG0791	NLP P60 protein
FDP11_17480	COG3706	GGDEF domain
FDP11_17485	COG2201	protein-glutamate methylesterase activity
FDP11_17490	COG3001	Fructosamine kinase
FDP11_17500	COG0307	riboflavin synthase, alpha
FDP11_17505	COG0534	Mate efflux family protein
FDP11_17515	COG1793	dna ligase
FDP11_17550	COG2204	response regulator
FDP11_17560	COG0438	transferase activity, transferring glycosyl groups
FDP11_17695	COG0653	protein targeting
FDP11_17860	COG1160	GTP binding
FDP11_17865	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
FDP11_17875	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FDP11_17915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FDP11_18120	COG1280	lysine exporter protein (LysE YggA)
FDP11_18145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FDP11_18370	COG0456	acetyltransferase
FDP11_18520	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FDP11_18580	COG0346	lactoylglutathione lyase activity
FDP11_18795	COG0346	lactoylglutathione lyase activity
FDP11_18835	COG2732	(Barnase) inhibitor
FDP11_18930	COG3152	Membrane
FDP11_19055	COG0456	acetyltransferase
FDP11_19085	COG0251	oxidation-reduction process
FDP11_19100	COG1280	lysine exporter protein (LysE YggA)
FDP11_19130	COG0346	lactoylglutathione lyase activity
FDP11_19185	COG0456	acetyltransferase
FDP11_19260	COG0517	IMP dehydrogenase activity
FDP11_19260	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FDP11_19475	COG0456	acetyltransferase
FDP11_19700	COG1280	lysine exporter protein (LysE YggA)
FDP11_19720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDP11_19730	COG3768	UPF0283 membrane protein
FDP11_19735	COG3106	COG3106 Predicted ATPase
FDP11_19755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FDP11_19760	COG2205	protein histidine kinase activity
FDP11_19760	COG0784	Response regulator, receiver
FDP11_19770	COG0494	nUDIX hydrolase
FDP11_19775	COG0814	amino acid
FDP11_19780	COG1760	l-serine dehydratase
FDP11_19785	COG2200	EAL domain
FDP11_19795	COG0720	synthase
FDP11_19805	COG0017	Asparaginyl-tRNA synthetase
FDP11_19815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDP11_19840	COG1448	Aminotransferase
FDP11_19860	COG0840	transmembrane signaling receptor activity
FDP11_19865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDP11_19870	COG1846	Transcriptional regulator
FDP11_19895	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FDP11_19910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDP11_19915	COG3108	Peptidase M15
FDP11_19920	COG2989	Protein conserved in bacteria
FDP11_19945	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDP11_19955	COG4235	cytochrome complex assembly
FDP11_19955	COG3088	subunit of a heme lyase
FDP11_19965	COG1138	Cytochrome C-type biogenesis protein
FDP11_19970	COG3301	Polysulphide reductase, NrfD
FDP11_19975	COG0437	4 iron, 4 sulfur cluster binding
FDP11_19985	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FDP11_20005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FDP11_20010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDP11_20015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDP11_20040	COG0019	diaminopimelate decarboxylase activity
FDP11_20080	COG0322	excinuclease ABC activity
FDP11_20085	COG2197	response regulator
FDP11_20090	COG0417	DNA replication proofreading
FDP11_20100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FDP11_20105	COG3099	Belongs to the UPF0263 family
FDP11_20115	COG1187	pseudouridine synthase activity
FDP11_20125	COG0009	L-threonylcarbamoyladenylate synthase
FDP11_20130	COG0613	PHP domain protein
FDP11_20140	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FDP11_20145	COG0512	Glutamine amidotransferase of anthranilate synthase
FDP11_20150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FDP11_20155	COG0135	phosphoribosylanthranilate isomerase activity
FDP11_20155	COG0134	indole-3-glycerol-phosphate synthase activity
FDP11_20160	COG0133	tryptophan synthase activity
FDP11_20165	COG0159	tryptophan synthase activity
FDP11_20175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDP11_20180	COG0318	PFAM AMP-dependent synthetase and ligase
FDP11_20190	COG1301	dicarboxylic acid transport
FDP11_20210	COG2917	probably involved in intracellular septation
FDP11_20220	COG2350	Protein conserved in bacteria
FDP11_20230	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FDP11_20240	COG0583	DNA-binding transcription factor activity
FDP11_20255	COG4251	negative regulation of phosphorylation
FDP11_20255	COG3706	GGDEF domain
FDP11_20255	COG2203	Gaf domain
FDP11_20255	COG5001	Diguanylate cyclase
FDP11_20260	COG1032	radical SAM domain protein
FDP11_20265	COG0840	transmembrane signaling receptor activity
FDP11_20275	COG0745	RESPONSE REGULATOR receiver
FDP11_20280	COG5002	protein histidine kinase activity
FDP11_20280	COG3850	Histidine kinase
FDP11_20320	COG1435	thymidine kinase activity
FDP11_20325	COG0215	cysteine-tRNA ligase activity
FDP11_20330	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FDP11_20335	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDP11_20340	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FDP11_20350	COG3012	SEC-C Motif Domain Protein
FDP11_20355	COG0140	phosphoribosyl-ATP diphosphatase activity
FDP11_20355	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FDP11_20360	COG0107	imidazoleglycerol-phosphate synthase activity
FDP11_20365	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FDP11_20370	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FDP11_20375	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FDP11_20375	COG0131	Imidazoleglycerol-phosphate dehydratase
FDP11_20380	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FDP11_20385	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FDP11_20390	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FDP11_20405	COG1757	Na H antiporter
FDP11_20415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDP11_20425	COG0482	sulfurtransferase activity
FDP11_20430	COG2915	High frequency lysogenization protein hflD homolog
FDP11_20435	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FDP11_20460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FDP11_20475	COG0300	oxidoreductase activity
FDP11_20485	COG0501	Belongs to the peptidase M48B family
FDP11_20495	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FDP11_20505	COG0156	8-amino-7-oxononanoate synthase activity
FDP11_20510	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FDP11_20515	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FDP11_20520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FDP11_20535	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FDP11_20540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FDP11_20545	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FDP11_20550	COG1674	ftsk spoiiie
FDP11_20560	COG0686	Belongs to the AlaDH PNT family
FDP11_20570	COG0583	DNA-binding transcription factor activity
FDP11_20585	COG3568	Endonuclease Exonuclease Phosphatase
FDP11_20615	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDP11_20620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDP11_20635	COG0840	transmembrane signaling receptor activity
FDP11_20650	COG0784	Response regulator, receiver
FDP11_20650	COG5002	protein histidine kinase activity
FDP11_20660	COG0754	glutathionylspermidine amidase activity
FDP11_20670	COG3766	membrane
FDP11_20680	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FDP11_20690	COG0366	Alpha amylase catalytic
FDP11_20695	COG1122	ATPase activity
FDP11_20700	COG4120	Belongs to the binding-protein-dependent transport system permease family
FDP11_20710	COG3092	negative regulation of chromosome organization
FDP11_20715	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FDP11_20720	COG0857	belongs to the CobB CobQ family
FDP11_20720	COG0280	phosphate acetyltransferase
FDP11_20725	COG3174	membrane
FDP11_20735	COG0435	Glutathione S-transferase
FDP11_20745	COG0444	Belongs to the ABC transporter superfamily
FDP11_20750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDP11_20755	COG0601	transmembrane transport
FDP11_20765	COG0314	molybdopterin synthase activity
FDP11_20770	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FDP11_20775	COG0315	cyclic pyranopterin monophosphate synthase activity
FDP11_20780	COG0521	Mo-molybdopterin cofactor biosynthetic process
FDP11_20785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FDP11_20790	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FDP11_20795	COG2198	Histidine kinase
FDP11_20800	COG2204	response regulator
FDP11_20805	COG0556	nucleotide-excision repair
FDP11_20860	COG1882	Formate acetyltransferase
FDP11_20870	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FDP11_20880	COG3013	Belongs to the UPF0304 family
FDP11_20890	COG2766	serine protein kinase
FDP11_20895	COG2718	Belongs to the UPF0229 family
FDP11_20900	COG2719	SpoVR family
FDP11_20905	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FDP11_20915	COG1663	tetraacyldisaccharide 4'-kinase activity
FDP11_20920	COG1132	(ABC) transporter
FDP11_20925	COG0658	competence protein
FDP11_20925	COG2333	competence protein COMEC
FDP11_20935	COG4591	ABC-type transport system involved in lipoprotein release permease component
FDP11_20940	COG1136	(ABC) transporter
FDP11_20945	COG4591	ABC-type transport system involved in lipoprotein release permease component
FDP11_20955	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FDP11_20970	COG1252	NADH dehydrogenase
FDP11_20980	COG3150	esterase
FDP11_21005	COG0537	adenosine 5'-monophosphoramidase activity
FDP11_21035	COG0517	IMP dehydrogenase activity
FDP11_21035	COG0516	GMP reductase activity
FDP11_21045	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FDP11_21050	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FDP11_21055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDP11_21065	COG2199	diguanylate cyclase activity
FDP11_21080	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FDP11_21085	COG1946	Acyl-CoA thioesterase
FDP11_21095	COG1522	sequence-specific DNA binding
FDP11_21125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDP11_21130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDP11_21175	COG0477	Major facilitator Superfamily
FDP11_21180	COG2855	membrane
FDP11_21200	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FDP11_21205	COG0596	Alpha beta hydrolase
FDP11_21210	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FDP11_21215	COG1169	isochorismate synthase
FDP11_21220	COG0436	Aminotransferase
FDP11_21225	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FDP11_21230	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FDP11_21245	COG1555	photosystem II stabilization
FDP11_21250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDP11_21255	COG0776	regulation of translation
FDP11_21260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FDP11_21265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FDP11_21275	COG0544	peptidyl-prolyl cis-trans isomerase activity
FDP11_21285	COG2204	response regulator
FDP11_21295	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FDP11_21300	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FDP11_21305	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FDP11_21310	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FDP11_21330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDP11_21335	COG0569	domain protein
FDP11_21340	COG0513	Belongs to the DEAD box helicase family
FDP11_21345	COG1253	flavin adenine dinucleotide binding
FDP11_21380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDP11_21385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDP11_21400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FDP11_21405	COG1216	Glycosyl transferase, family 2
FDP11_21410	COG2986	histidine ammonia-lyase
FDP11_21435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FDP11_21445	COG1028	Short-chain dehydrogenase reductase Sdr
FDP11_21460	COG0582	viral genome integration into host DNA
FDP11_21465	COG3550	peptidyl-serine autophosphorylation
FDP11_21470	COG1396	sequence-specific DNA binding
FDP11_21555	COG0732	type I restriction modification DNA specificity domain
FDP11_21590	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FDP11_21595	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FDP11_21600	COG0583	DNA-binding transcription factor activity
FDP11_21605	COG2951	lytic endotransglycosylase activity
FDP11_21610	COG3100	YcgL domain-containing protein
FDP11_21615	COG0850	regulation of cytokinetic process
FDP11_21620	COG2894	cell division
FDP11_21625	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FDP11_21630	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FDP11_21635	COG0318	PFAM AMP-dependent synthetase and ligase
FDP11_21640	COG2267	carboxylic ester hydrolase activity
FDP11_21655	COG1214	PFAM Peptidase M22, glycoprotease
FDP11_21660	COG1199	ATP-dependent helicase activity
FDP11_21665	COG0788	formyltetrahydrofolate deformylase activity
FDP11_21680	COG3102	Protein conserved in bacteria
FDP11_21690	COG0018	arginyl-trna synthetase
FDP11_21710	COG1918	ferrous iron import across plasma membrane
FDP11_21725	COG4977	sequence-specific DNA binding
FDP11_21730	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FDP11_21735	COG1121	(ABC) transporter
FDP11_21740	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FDP11_21745	COG0121	glutamine amidotransferase
FDP11_21750	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FDP11_21755	COG1960	acyl-CoA dehydrogenase activity
FDP11_21765	COG0456	acetyltransferase
FDP11_21790	COG0328	RNA-DNA hybrid ribonuclease activity
FDP11_21795	COG2226	methyltransferase
FDP11_21800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDP11_21805	COG0741	lytic transglycosylase activity
FDP11_21805	COG1388	LysM domain
FDP11_21815	COG3021	interspecies interaction between organisms
FDP11_21820	COG0347	Belongs to the P(II) protein family
FDP11_21830	COG0037	tRNA processing
FDP11_21835	COG0825	malonyl-CoA metabolic process
FDP11_21840	COG0587	DNA-directed DNA polymerase activity
FDP11_21850	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDP11_21855	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FDP11_21860	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDP11_21865	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FDP11_21875	COG0750	zinc metalloprotease
FDP11_21880	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FDP11_21885	COG0575	Belongs to the CDS family
FDP11_21890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FDP11_21895	COG0233	cytoplasmic translational termination
FDP11_21900	COG0528	UMP kinase activity
FDP11_21905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FDP11_21910	COG0052	Belongs to the universal ribosomal protein uS2 family
FDP11_21915	COG0024	Methionine aminopeptidase
FDP11_21920	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FDP11_21930	COG0564	pseudouridine synthase activity
FDP11_21935	COG3098	single-species biofilm formation
FDP11_21960	COG1671	Belongs to the UPF0178 family
FDP11_21965	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FDP11_21980	COG0254	rRNA binding
FDP11_21985	COG1720	tRNA m6t6A37 methyltransferase activity
FDP11_21990	COG0442	prolyl-tRNA aminoacylation
FDP11_22010	COG0733	neurotransmitter:sodium symporter activity
FDP11_22025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDP11_22030	COG0514	ATP-dependent DNA helicase (RecQ)
FDP11_22035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDP11_22050	COG1477	protein flavinylation
FDP11_22055	COG2871	sodium ion transport
FDP11_22060	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FDP11_22065	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FDP11_22070	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FDP11_22075	COG1805	sodium ion transport
FDP11_22080	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FDP11_22085	COG0271	Belongs to the BolA IbaG family
FDP11_22090	COG2813	Specifically methylates the guanine in position
FDP11_22095	COG3056	Lipoprotein
FDP11_22115	COG1595	DNA-templated transcription, initiation
FDP11_22145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FDP11_22150	COG0693	protein deglycase activity
FDP11_22155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FDP11_22160	COG3706	GGDEF domain
FDP11_22165	COG2166	iron-sulfur cluster assembly
FDP11_22170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FDP11_22175	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FDP11_22190	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FDP11_22190	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FDP11_22210	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDP11_22215	COG1074	ATP-dependent DNA helicase activity
FDP11_22225	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FDP11_22245	COG3141	response to X-ray
FDP11_22250	COG2171	N-acyltransferase activity
FDP11_22255	COG0584	glycerophosphoryl diester phosphodiesterase
FDP11_22260	COG2271	Major facilitator Superfamily
FDP11_22275	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FDP11_22280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FDP11_22285	COG1349	DNA-binding transcription factor activity
FDP11_22290	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FDP11_22295	COG0598	Magnesium transport protein CorA
FDP11_22310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDP11_22315	COG1609	Transcriptional regulator
FDP11_22320	COG2176	DNA-directed DNA polymerase activity
FDP11_22335	COG2017	converts alpha-aldose to the beta-anomer
FDP11_22340	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FDP11_22350	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDP11_22360	COG1609	Transcriptional regulator
FDP11_22365	COG3250	beta-galactosidase activity
FDP11_22370	COG2731	YhcH YjgK YiaL family protein
FDP11_22375	COG0531	amino acid
FDP11_22380	COG0583	DNA-binding transcription factor activity
FDP11_22440	COG4964	Belongs to the GSP D family
FDP11_22465	COG2169	Transcriptional regulator
FDP11_22470	COG1022	Amp-dependent synthetase and ligase
FDP11_22480	COG0583	DNA-binding transcription factor activity
FDP11_22485	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FDP11_22490	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FDP11_22500	COG0560	Phosphoserine phosphatase
FDP11_22510	COG0813	purine-nucleoside phosphorylase activity
FDP11_22515	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FDP11_22520	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FDP11_22525	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FDP11_22530	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FDP11_22535	COG0084	hydrolase, TatD family'
FDP11_22545	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FDP11_22565	COG3153	acetyltransferase
FDP11_22570	COG3154	lipid carrier protein
FDP11_22580	COG0826	peptidase U32
FDP11_22585	COG0826	peptidase U32
FDP11_22590	COG0534	Mate efflux family protein
FDP11_22605	COG1185	polyribonucleotide nucleotidyltransferase activity
FDP11_22610	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FDP11_22615	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FDP11_22620	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FDP11_22625	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FDP11_22630	COG0195	Participates in both transcription termination and antitermination
FDP11_22635	COG0779	Required for maturation of 30S ribosomal subunits
FDP11_22650	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FDP11_22660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDP11_22665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FDP11_22670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDP11_22675	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FDP11_22680	COG1534	Rna-binding protein
FDP11_22685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDP11_22690	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FDP11_22695	COG2027	D-alanyl-D-alanine carboxypeptidase
FDP11_22715	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FDP11_22745	COG0484	heat shock protein binding
FDP11_22750	COG0443	Heat shock 70 kDa protein
FDP11_22760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FDP11_22765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FDP11_22775	COG0497	DNA recombination
FDP11_22780	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDP11_22785	COG2914	Belongs to the UPF0125 (RnfH) family
FDP11_22790	COG2867	negative regulation of translational initiation
FDP11_22795	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FDP11_22835	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FDP11_22855	COG0583	DNA-binding transcription factor activity
FDP11_22860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDP11_22860	COG3153	acetyltransferase
FDP11_22880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FDP11_22885	COG2873	o-acetylhomoserine
FDP11_22920	COG1115	amino acid carrier protein
FDP11_22930	COG1584	GPR1 FUN34 yaaH family protein
FDP11_22940	COG1757	Na H antiporter
FDP11_22945	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDP11_22945	COG0519	Catalyzes the synthesis of GMP from XMP
FDP11_22950	COG0516	GMP reductase activity
FDP11_22950	COG0517	IMP dehydrogenase activity
FDP11_22955	COG1570	exodeoxyribonuclease VII activity
FDP11_22970	COG1160	GTP binding
FDP11_22975	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDP11_22980	COG2976	Protein conserved in bacteria
FDP11_22985	COG0124	histidyl-tRNA synthetase
FDP11_22990	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FDP11_23005	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FDP11_23010	COG0105	UTP biosynthetic process
FDP11_23015	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FDP11_23020	COG2975	iron-sulfur cluster assembly
FDP11_23025	COG0633	Ferredoxin
FDP11_23030	COG0443	Heat shock 70 kDa protein
FDP11_23035	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FDP11_23045	COG0822	iron-sulfur transferase activity
FDP11_23050	COG1104	cysteine desulfurase activity
FDP11_23065	COG0483	inositol monophosphate 1-phosphatase activity
FDP11_23075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDP11_23080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDP11_23085	COG1862	Preprotein translocase
FDP11_23090	COG0343	queuine tRNA-ribosyltransferase activity
FDP11_23095	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FDP11_23110	COG0517	IMP dehydrogenase activity
FDP11_23120	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FDP11_23130	COG0583	DNA-binding transcription factor activity
FDP11_23135	COG0450	alkyl hydroperoxide reductase
FDP11_23145	COG3142	Participates in the control of copper homeostasis
FDP11_23155	COG0704	Plays a role in the regulation of phosphate uptake
FDP11_23160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDP11_23165	COG0581	inorganic phosphate transmembrane transporter activity
FDP11_23175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FDP11_23180	COG0248	Ppx GppA phosphatase
FDP11_23190	COG5002	protein histidine kinase activity
FDP11_23195	COG0745	RESPONSE REGULATOR receiver
FDP11_23205	COG2974	May be involved in recombination
FDP11_23215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDP11_23280	COG0542	response to heat
FDP11_23290	COG0564	pseudouridine synthase activity
FDP11_23295	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDP11_23300	COG0741	lytic transglycosylase activity
FDP11_23305	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FDP11_23310	COG1605	Chorismate mutase
FDP11_23310	COG0077	Prephenate dehydratase
FDP11_23315	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FDP11_23320	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FDP11_23330	COG0488	(ABC) transporter
FDP11_23345	COG0739	heme binding
FDP11_23350	COG0287	Prephenate dehydrogenase
FDP11_23350	COG1605	Chorismate mutase
FDP11_23355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDP11_23360	COG1472	Belongs to the glycosyl hydrolase 3 family
FDP11_23365	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FDP11_23370	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FDP11_23385	COG1966	Carbon starvation protein
FDP11_23390	COG3275	phosphorelay sensor kinase activity
FDP11_23395	COG3279	Response regulator of the LytR AlgR family
FDP11_23400	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FDP11_23405	COG1047	Peptidyl-prolyl cis-trans
FDP11_23410	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FDP11_23415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDP11_23420	COG0196	riboflavin kinase activity
FDP11_23425	COG0728	peptidoglycan biosynthetic process
FDP11_23430	COG0268	Binds directly to 16S ribosomal RNA
FDP11_23440	COG0640	Transcriptional regulator
FDP11_23450	COG0583	DNA-binding transcription factor activity
FDP11_23455	COG1283	sodium-dependent phosphate transmembrane transporter activity
FDP11_23465	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FDP11_23470	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FDP11_23475	COG0730	response to heat
FDP11_23480	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FDP11_23485	COG0494	nUDIX hydrolase
FDP11_23495	COG3066	DNA modification
FDP11_23505	COG0667	Aldo Keto reductase
FDP11_23520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FDP11_23530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FDP11_23535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDP11_23540	COG4974	Belongs to the 'phage' integrase family
FDP11_23545	COG0716	FMN binding
FDP11_23555	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FDP11_23560	COG0513	Belongs to the DEAD box helicase family
FDP11_23565	COG3022	response to hydroperoxide
FDP11_23570	COG1115	amino acid carrier protein
FDP11_23585	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FDP11_23595	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FDP11_23600	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FDP11_23605	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FDP11_23610	COG0083	homoserine kinase activity
FDP11_23625	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDP11_23640	COG0745	RESPONSE REGULATOR receiver
FDP11_23650	COG5002	protein histidine kinase activity
FDP11_23650	COG0784	Response regulator, receiver
FDP11_23650	COG2198	Histidine kinase
FDP11_23655	COG5001	Diguanylate cyclase
FDP11_23655	COG4251	negative regulation of phosphorylation
FDP11_23655	COG3706	GGDEF domain
FDP11_23655	COG2203	Gaf domain
FDP11_23660	COG1242	4 iron, 4 sulfur cluster binding
FDP11_23665	COG0069	glutamate synthase activity
FDP11_23665	COG0067	glutamate synthase
FDP11_23665	COG0070	glutamate synthase
FDP11_23675	COG0070	glutamate synthase
FDP11_23675	COG0069	glutamate synthase activity
FDP11_23675	COG0067	glutamate synthase
FDP11_23680	COG0493	'glutamate synthase
FDP11_23690	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDP11_23700	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FDP11_23705	COG2860	membrane
FDP11_23710	COG0583	DNA-binding transcription factor activity
FDP11_23725	COG0730	response to heat
FDP11_23740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FDP11_23745	COG0505	Belongs to the CarA family
FDP11_23750	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FDP11_23755	COG0494	nUDIX hydrolase
FDP11_23760	COG0653	protein targeting
FDP11_23770	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FDP11_23775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FDP11_23780	COG0849	cell division
FDP11_23785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FDP11_23790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDP11_23795	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FDP11_23800	COG0772	Belongs to the SEDS family
FDP11_23805	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FDP11_23810	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FDP11_23815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FDP11_23820	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FDP11_23825	COG0768	penicillin binding
FDP11_23830	COG3116	cell division
FDP11_23835	COG0275	rRNA processing
FDP11_23850	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FDP11_23860	COG0792	nuclease activity
FDP11_23865	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FDP11_23870	COG2823	Periplasmic or secreted lipoprotein
FDP11_23875	COG2969	positive regulation of protein catabolic process
FDP11_23880	COG0625	glutathione transferase activity
FDP11_23885	COG2857	Cytochrome c1
FDP11_23890	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FDP11_23895	COG0723	plastoquinol--plastocyanin reductase activity
FDP11_23900	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FDP11_23905	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FDP11_23915	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FDP11_23925	COG3105	Protein conserved in bacteria
FDP11_23935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDP11_23940	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FDP11_23950	COG3150	esterase
FDP11_23960	COG3151	Protein conserved in bacteria
FDP11_23965	COG0494	nUDIX hydrolase
FDP11_23970	COG1538	Outer membrane efflux protein
FDP11_23975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FDP11_23975	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FDP11_23980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FDP11_23995	COG3025	triphosphatase activity
FDP11_24000	COG1392	Phosphate transport regulator
FDP11_24005	COG0306	phosphate transporter
FDP11_24010	COG4991	sh3 domain protein
FDP11_24020	COG3409	Peptidoglycan-binding domain 1 protein
FDP11_24020	COG3267	Type II secretory pathway component ExeA
FDP11_24025	COG0617	tRNA 3'-terminal CCA addition
FDP11_24030	COG1968	undecaprenyl-diphosphatase activity
FDP11_24035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDP11_24040	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FDP11_24045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FDP11_24050	COG0596	Alpha beta hydrolase
FDP11_24055	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FDP11_24060	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FDP11_24065	COG1610	YqeY-like protein
FDP11_24070	COG0358	DNA primase activity
FDP11_24085	COG0582	viral genome integration into host DNA
FDP11_24100	COG2172	sigma factor antagonist activity
FDP11_24120	COG2003	Belongs to the UPF0758 family
FDP11_24165	COG0328	RNA-DNA hybrid ribonuclease activity
FDP11_24195	COG1464	Belongs to the NlpA lipoprotein family
FDP11_24230	COG2213	PTS system mannitol-specific
FDP11_24230	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDP11_24235	COG0246	Mannitol dehydrogenase
FDP11_24240	COG3722	fumarate hydratase activity
FDP11_24245	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDP11_24250	COG5002	protein histidine kinase activity
FDP11_24265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FDP11_24270	COG1349	DNA-binding transcription factor activity
FDP11_24280	COG0469	pyruvate kinase activity
FDP11_24290	COG3706	GGDEF domain
FDP11_24295	COG0440	acetolactate synthase activity
FDP11_24300	COG0028	Belongs to the TPP enzyme family
FDP11_24305	COG1022	Amp-dependent synthetase and ligase
FDP11_24310	COG0583	DNA-binding transcription factor activity
FDP11_24330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDP11_24335	COG0473	3-isopropylmalate dehydrogenase activity
FDP11_24340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FDP11_24345	COG0066	3-isopropylmalate dehydratase activity
FDP11_24355	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FDP11_24360	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FDP11_24365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDP11_24370	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FDP11_24375	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FDP11_24380	COG2967	ApaG domain
FDP11_24385	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDP11_24400	COG2966	Psort location CytoplasmicMembrane, score
FDP11_24405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FDP11_24415	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FDP11_24420	COG0142	geranyltranstransferase activity
FDP11_24430	COG0039	L-malate dehydrogenase activity
FDP11_24445	COG2358	TRAP transporter, solute receptor (TAXI family
FDP11_24465	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FDP11_24470	COG1178	ABC-type Fe3 transport system permease component
FDP11_24475	COG4143	(ABC) transporter
FDP11_24480	COG0163	prenyltransferase activity
FDP11_24485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDP11_24495	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FDP11_24500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FDP11_24510	COG2105	PFAM AIG2 family protein
FDP11_24515	COG2911	Protein conserved in bacteria
FDP11_24520	COG0729	surface antigen
FDP11_24525	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FDP11_24535	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FDP11_24550	COG4181	ATPase activity
FDP11_24570	COG0529	Catalyzes the synthesis of activated sulfate
FDP11_24575	COG3273	potassium ion transport
FDP11_24575	COG0471	metal ion transport
FDP11_24585	COG2895	sulfate adenylyltransferase (ATP) activity
FDP11_24590	COG0175	sulfate reduction
FDP11_24595	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FDP11_24595	COG1648	precorrin-2 dehydrogenase activity
FDP11_24600	COG0737	Belongs to the 5'-nucleotidase family
FDP11_24610	COG0513	Belongs to the DEAD box helicase family
FDP11_24615	COG2153	protein acetylation
FDP11_24625	COG0545	Peptidyl-prolyl cis-trans isomerase
FDP11_24635	COG0203	ribosomal protein L17
FDP11_24640	COG0202	RNA polymerase activity
FDP11_24650	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FDP11_24655	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FDP11_24660	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FDP11_24665	COG0201	protein transport
FDP11_24670	COG0200	Binds to the 23S rRNA
FDP11_24675	COG1841	ribosomal large subunit assembly
FDP11_24690	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FDP11_24695	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FDP11_24700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FDP11_24705	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FDP11_24710	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FDP11_24715	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FDP11_24720	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FDP11_24725	COG0255	Belongs to the universal ribosomal protein uL29 family
FDP11_24735	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FDP11_24740	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FDP11_24745	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FDP11_24750	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FDP11_24760	COG0088	Forms part of the polypeptide exit tunnel
FDP11_24765	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FDP11_24775	COG0254	rRNA binding
FDP11_24785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FDP11_24790	COG1609	Transcriptional regulator
FDP11_24800	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FDP11_24805	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FDP11_24810	COG1575	Belongs to the MenA family. Type 1 subfamily
FDP11_24815	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDP11_24820	COG3074	FtsZ-dependent cytokinesis
FDP11_24830	COG1494	fructose-1,6-bisphosphatase
FDP11_24855	COG0149	triose-phosphate isomerase activity
FDP11_24880	COG0438	transferase activity, transferring glycosyl groups
FDP11_24880	COG1216	Glycosyl transferase, family 2
FDP11_24890	COG3273	potassium ion transport
FDP11_24890	COG0471	metal ion transport
FDP11_24920	COG0438	transferase activity, transferring glycosyl groups
FDP11_24920	COG1216	Glycosyl transferase, family 2
FDP11_24930	COG1051	belongs to the nudix hydrolase family
FDP11_24935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FDP11_24940	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FDP11_24955	COG0517	IMP dehydrogenase activity
FDP11_24955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FDP11_24960	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FDP11_24965	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FDP11_24990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDP11_25005	COG1088	dTDP-glucose 4,6-dehydratase activity
FDP11_25045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FDP11_25075	COG3156	type II secretion system protein K
FDP11_25095	COG1459	type II secretion system
FDP11_25100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDP11_25115	COG0175	sulfate reduction
FDP11_25120	COG0529	Catalyzes the synthesis of activated sulfate
FDP11_25130	COG2895	sulfate adenylyltransferase (ATP) activity
FDP11_25135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FDP11_25155	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDP11_25165	COG1560	Kdo2-lipid A biosynthetic process
FDP11_25170	COG0859	PFAM glycosyl transferase family 9
FDP11_25175	COG1519	Transferase
FDP11_25185	COG1083	cytidylyl-transferase
FDP11_25190	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FDP11_25200	COG2089	acid synthase
FDP11_25205	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FDP11_25210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FDP11_25215	COG1086	Polysaccharide biosynthesis protein
FDP11_25220	COG1045	serine acetyltransferase
FDP11_25240	COG3642	lipopolysaccharide core region biosynthetic process
FDP11_25245	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FDP11_25250	COG0859	PFAM glycosyl transferase family 9
FDP11_25255	COG0463	Glycosyl transferase, family 2
FDP11_25265	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FDP11_25275	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FDP11_25290	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FDP11_25295	COG2003	Belongs to the UPF0758 family
FDP11_25310	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FDP11_25315	COG1309	transcriptional regulator
FDP11_25320	COG1560	Kdo2-lipid A biosynthetic process
FDP11_25325	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FDP11_25330	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FDP11_25335	COG1561	YicC-like family, N-terminal region
FDP11_25345	COG4608	Belongs to the ABC transporter superfamily
FDP11_25350	COG0444	Belongs to the ABC transporter superfamily
FDP11_25355	COG0747	negative chemotaxis
FDP11_25360	COG4239	(ABC) transporter, permease
FDP11_25365	COG4174	ABC transporter (Permease)
FDP11_25390	COG0811	peptide transport
FDP11_25395	COG0848	biopolymer transport protein
FDP11_25410	COG0194	GDP metabolic process
FDP11_25415	COG1758	RNA polymerase activity
FDP11_25420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDP11_25425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDP11_25430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FDP11_25440	COG2233	PERMEase
FDP11_25445	COG2205	protein histidine kinase activity
FDP11_25450	COG0745	RESPONSE REGULATOR receiver
FDP11_25460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDP11_25470	COG2183	response to ionizing radiation
FDP11_25480	COG0596	Alpha beta hydrolase
FDP11_25485	COG1040	competence protein
FDP11_25490	COG0316	Belongs to the HesB IscA family
FDP11_25490	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FDP11_25495	COG0494	nUDIX hydrolase
FDP11_25500	COG1218	3'(2'),5'-bisphosphate nucleotidase
FDP11_25510	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FDP11_25515	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FDP11_25520	COG3156	type II secretion system protein K
FDP11_25525	COG4795	General secretion pathway protein
FDP11_25530	COG2165	general secretion pathway protein
FDP11_25535	COG2165	general secretion pathway protein
FDP11_25540	COG2165	general secretion pathway protein
FDP11_25545	COG1459	type II secretion system
FDP11_25550	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDP11_25560	COG3031	protein transport across the cell outer membrane
FDP11_25565	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FDP11_25570	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FDP11_25575	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FDP11_25585	COG0456	acetyltransferase
FDP11_25590	COG1490	D-aminoacyl-tRNA deacylase activity
FDP11_25595	COG1295	ribonuclease BN
FDP11_25615	COG0174	glutamine synthetase
FDP11_25625	COG3852	Histidine kinase
FDP11_25630	COG2204	response regulator
FDP11_25640	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FDP11_25675	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FDP11_25685	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FDP11_25685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FDP11_25710	COG0084	hydrolase, TatD family'
FDP11_25720	COG0805	protein transport
FDP11_25725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FDP11_25730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FDP11_25735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDP11_25740	COG3165	ubiquinone biosynthetic process from chorismate
FDP11_25745	COG2226	methyltransferase
FDP11_25750	COG1322	Protein conserved in bacteria
FDP11_25765	COG0628	permease
FDP11_25825	COG2081	HI0933 family
FDP11_25835	COG1528	Iron-storage protein
FDP11_25840	COG0589	response to stress
FDP11_25855	COG0742	ribosomal rna small subunit methyltransferase
FDP11_25860	COG5001	Diguanylate cyclase
FDP11_25860	COG5002	protein histidine kinase activity
FDP11_25865	COG1522	sequence-specific DNA binding
FDP11_25870	COG0339	signal peptide processing
FDP11_25875	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FDP11_25880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDP11_25885	COG0583	DNA-binding transcription factor activity
FDP11_25890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FDP11_25895	COG0800	Aldolase
FDP11_25900	COG2610	gluconate transmembrane transporter activity
FDP11_25905	COG3265	gluconokinase activity
FDP11_25910	COG0129	dihydroxy-acid dehydratase activity
FDP11_25925	COG0583	DNA-binding transcription factor activity
FDP11_25930	COG1609	Transcriptional regulator
FDP11_25970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDP11_25980	COG0747	negative chemotaxis
FDP11_25985	COG4172	Belongs to the ABC transporter superfamily
FDP11_26050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDP11_26055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDP11_26065	COG2960	long-chain fatty acid transporting porin activity
FDP11_26070	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FDP11_26075	COG0583	DNA-binding transcription factor activity
FDP11_26120	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FDP11_26130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FDP11_26135	COG0408	coproporphyrinogen oxidase activity
FDP11_26140	COG0009	L-threonylcarbamoyladenylate synthase
FDP11_26145	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FDP11_26150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FDP11_26155	COG0551	DNA topoisomerase type I activity
FDP11_26160	COG2922	Belongs to the Smg family
FDP11_26165	COG0758	DNA mediated transformation
FDP11_26175	COG0242	peptide deformylase activity
FDP11_26180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FDP11_26185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FDP11_26185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FDP11_26190	COG0569	domain protein
FDP11_26195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDP11_26205	COG1272	protein, Hemolysin III
FDP11_26210	COG4326	sporulation control protein
FDP11_26220	COG3084	Protein conserved in bacteria
FDP11_26230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FDP11_26235	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDP11_26240	COG0204	Acyl-transferase
FDP11_26250	COG0606	chelatase, subunit chli
FDP11_26260	COG3978	acetolactate synthase activity
FDP11_26265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FDP11_26270	COG0129	dihydroxy-acid dehydratase activity
FDP11_26280	COG0583	DNA-binding transcription factor activity
FDP11_26285	COG2814	Major facilitator Superfamily
FDP11_26290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDP11_26295	COG0765	amino acid transport
FDP11_26300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FDP11_26305	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FDP11_26310	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FDP11_26315	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FDP11_26320	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FDP11_26325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FDP11_26340	COG0356	it plays a direct role in the translocation of protons across the membrane
FDP11_26345	COG3312	ion transport
FDP11_26350	COG1475	DNA binding
FDP11_26355	COG1192	Involved in chromosome partitioning
FDP11_26360	COG0357	Ribosomal RNA small subunit methyltransferase G
FDP11_26365	COG0445	tRNA wobble uridine modification
FDP11_26370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FDP11_26375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FDP11_26380	COG0706	membrane insertase activity
FDP11_26390	COG0594	ribonuclease P activity
FDP11_26400	COG1126	abc transporter atp-binding protein
FDP11_26425	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FDP11_26430	COG0592	DNA-directed DNA polymerase activity
FDP11_26435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FDP11_26440	COG0187	DNA topoisomerase II activity
FDP11_26460	COG0071	Belongs to the small heat shock protein (HSP20) family
FDP11_26465	COG3977	Valine--pyruvate aminotransferase
FDP11_26470	COG0366	Alpha amylase catalytic
FDP11_26475	COG0751	glycine-tRNA ligase activity
FDP11_26480	COG0752	glycyl-tRNA synthetase alpha subunit
FDP11_26485	COG2119	membrane
FDP11_26495	COG0425	Belongs to the sulfur carrier protein TusA family
FDP11_26510	COG0604	alcohol dehydrogenase
FDP11_26515	COG0183	Belongs to the thiolase family
FDP11_26520	COG1024	Enoyl-CoA hydratase
FDP11_26520	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDP11_26525	COG1739	Uncharacterized protein family UPF0029
FDP11_26530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDP11_26585	COG3335	DDE superfamily endonuclease
FDP11_26595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FDP11_26600	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FDP11_26605	COG0352	thiamine-phosphate diphosphorylase activity
FDP11_26610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FDP11_26615	COG2104	thiamine diphosphate biosynthetic process
FDP11_26620	COG2022	thiamine diphosphate biosynthetic process
FDP11_26630	COG0006	proline dipeptidase activity
FDP11_26630	COG0006	proline dipeptidase activity
FDP11_26660	COG3220	belongs to the UPF0276 family
FDP11_26670	COG0210	DNA helicase
FDP11_26680	COG0405	Gamma-glutamyltransferase
FDP11_26685	COG1280	lysine exporter protein (LysE YggA)
FDP11_26695	COG2962	Rard protein
FDP11_26700	COG0514	ATP-dependent DNA helicase (RecQ)
FDP11_26715	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FDP11_26720	COG0248	Ppx GppA phosphatase
FDP11_26725	COG0513	Belongs to the DEAD box helicase family
FDP11_26730	COG3118	belongs to the thioredoxin family
FDP11_26750	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FDP11_26755	COG0633	Ferredoxin
FDP11_26810	COG3071	HemY protein
FDP11_26815	COG2959	enzyme of heme biosynthesis
FDP11_26820	COG1587	Uroporphyrinogen-III synthase
FDP11_26825	COG0181	hydroxymethylbilane synthase activity
FDP11_26830	COG3072	Adenylate cyclase
FDP11_26835	COG1965	Belongs to the frataxin family
FDP11_26845	COG0019	diaminopimelate decarboxylase activity
FDP11_26850	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan