locus-tag class description BGM07_000020 ENOG4108JQ7 (ABC) transporter BGM07_000045 ENOG4105BZU Histidine kinase BGM07_000055 ENOG4105CDY transcriptional regulatory protein BGM07_000060 ENOG4105CNI cell division protein FtsW BGM07_000095 ENOG4108HRK Histidine kinase BGM07_000100 ENOG4108VAC response regulator BGM07_000110 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BGM07_000115 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_000140 ENOG4105D6U Sodium Glutamate Symporter BGM07_000150 ENOG4105DVE abc transporter atp-binding protein BGM07_000155 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BGM07_000160 ENOG4105D6U Sodium Glutamate Symporter BGM07_000175 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BGM07_000195 ENOG4105C2I pirin domain protein BGM07_000200 ENOG4108VGI doxx family BGM07_000210 ENOG4105D03 DNA-3-methyladenine glycosylase II BGM07_000215 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BGM07_000240 ENOG4105DN9 Na H antiporter BGM07_000270 ENOG4105NBK UPF0345 protein BGM07_000280 ENOG4108K0B C-di-gmp phosphodiesterase BGM07_000290 ENOG4105UQX Mate efflux family protein BGM07_000295 ENOG4105D3G Pseudouridine synthase BGM07_000310 ENOG4105EJC lysr family transcriptional regulator BGM07_000315 ENOG4108HCJ Hydrolase BGM07_000325 ENOG4108KHX Diguanylate cyclase BGM07_000335 ENOG4105C4W S-formylglutathione hydrolase BGM07_000345 ENOG4108MUX N-hydroxyarylamine O-acetyltransferase BGM07_000350 ENOG4105CC0 LysR family Transcriptional regulator BGM07_000365 ENOG4105J4Q Transcriptional regulator BGM07_000370 ENOG4105CHR reductase BGM07_000375 ENOG4105P66 Membrane BGM07_000380 ENOG4105M5J Cupin 2, conserved barrel domain protein BGM07_000395 ENOG4107SS6 2-dehydro-3-deoxygluconokinase BGM07_000400 ENOG4108UHU Aldolase BGM07_000425 ENOG4105CAZ oligogalacturonide lyase BGM07_000430 ENOG4105Q26 Siderophore-interacting protein BGM07_000440 ENOG4105EW9 transcriptional regulator AsnC family BGM07_000460 ENOG4107W31 Pentapeptide repeat protein BGM07_000465 ENOG4105EIF outer membrane protein W BGM07_000475 ENOG4105C0R drug resistance transporter emrb qaca subfamily BGM07_000495 ENOG4107WCA isomerase BGM07_000500 ENOG4108UVJ appr-1-p processing domain protein BGM07_000505 ENOG4109025 Glyoxalase Bleomycin resistance protein (Dioxygenase BGM07_000510 ENOG4108WAV Transcriptional regulator BGM07_000535 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 BGM07_000560 ENOG4108IXP Carbohydrate diacid transcriptional activator CdaR BGM07_000565 ENOG4105C6Z Gluconate BGM07_000570 ENOG4105BZW Glycerate kinase BGM07_000575 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BGM07_000610 ENOG4105CYX Short-chain dehydrogenase reductase Sdr BGM07_000620 ENOG4105CUW cytochrome C-TYPE protein BGM07_000625 ENOG4107QY8 reductase BGM07_000635 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BGM07_000640 ENOG4105C4U 4-methyl-5-beta-hydroxyethylthiazole kinase BGM07_000645 ENOG4105ETU transcriptional activator (TenA BGM07_000650 ENOG4107Z6I Thiamine biosynthesis protein BGM07_000655 ENOG4105Y36 Binding-protein-dependent transport systems, inner membrane component BGM07_000660 ENOG4108YI8 ABC transporter BGM07_000665 ENOG4105DWF phosphomethylpyrimidine kinase BGM07_000680 ENOG4108TEM pseudouridine methyltransferase BGM07_000730 ENOG4108YYI Protein of unknown function (DUF2810) BGM07_000735 ENOG4105C5I Dehydrogenase BGM07_000745 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BGM07_000750 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BGM07_000755 ENOG4105E3W Two component transcriptional regulator (Winged helix family BGM07_000760 ENOG410804D Sensor Signal Transduction Histidine Kinase BGM07_000785 ENOG4109015 Biopolymer transport protein exbD tolR BGM07_000830 ENOG4105DIK (ABC) transporter BGM07_000835 ENOG4105CC5 ABC transporter BGM07_000850 ENOG4105CUG Oligopeptidase b BGM07_000855 ENOG4105E5M Multidrug resistance protein D BGM07_000860 ENOG4105CYW agmatinase BGM07_000865 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) BGM07_000875 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) BGM07_000880 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) BGM07_000890 ENOG4105DUM transcriptional regulator, lysR family BGM07_000930 ENOG4105CQZ Histidine kinase BGM07_000935 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM07_000940 ENOG4105BZU Histidine kinase BGM07_000945 ENOG4105CWM branched-chain amino acid transport system II carrier protein BGM07_000960 ENOG4105D5U fad dependent oxidoreductase BGM07_000970 ENOG4105C0F tryptophanase EC 4.1.99.1 BGM07_000985 ENOG4105D9N nucleoside BGM07_000995 ENOG4105CF1 Alkylated DNA repair protein BGM07_001000 ENOG4105BZU Histidine kinase BGM07_001005 ENOG4108N3W hemolysin secretion protein BGM07_001020 ENOG4106TD9 Diguanylate cyclase BGM07_001025 ENOG4105CVP deoxyribo-dipyrimidine photolyase BGM07_001030 ENOG4105EXX Deoxyribodipyrimidine photolyase-related protein BGM07_001045 ENOG4105E0X reductase BGM07_001050 ENOG4108UKZ OsmC family BGM07_001055 ENOG4108UW5 maltose o-acetyltransferase BGM07_001110 ENOG4105E0X reductase BGM07_001115 ENOG4108UKZ OsmC family BGM07_001120 ENOG4108UW5 maltose o-acetyltransferase BGM07_001155 ENOG4105JQN Transcriptional regulator BGM07_001160 ENOG4105PAD Hydrolase BGM07_001175 ENOG4108UUE Transcriptional regulator BGM07_001185 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BGM07_001190 ENOG4105DJY efflux transporter, rnd family, mfp subunit BGM07_001195 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BGM07_001205 ENOG4105KUU lipolytic protein G-D-S-L family BGM07_001210 ENOG4105RX7 peptidase S8 and S53, subtilisin, kexin, sedolisin BGM07_001235 ENOG4105ETE Transcriptional regulator (LacI family BGM07_001240 ENOG4108KAZ Involved in phosphonate degradation (By similarity) BGM07_001245 ENOG4108JPW Aminotransferase BGM07_001250 ENOG4107STF Involved in phosphonate degradation (By similarity) BGM07_001270 ENOG4107RCV ABC transporter, permease BGM07_001290 ENOG4108MJ5 VirK protein BGM07_001305 ENOG4105CJP fad dependent oxidoreductase BGM07_001320 ENOG4105ETT transcriptional Regulator, LysR family BGM07_001340 ENOG4105DUX Transporter BGM07_001345 ENOG4105EJQ L-serine dehydratase BGM07_001365 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BGM07_001370 ENOG4105E4C Lytic transglycosylase catalytic BGM07_001390 ENOG4105Q75 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BGM07_001395 ENOG4108ZC9 flagellar basal-body rod protein flgc BGM07_001400 ENOG4105W00 Flagellar hook capping protein BGM07_001405 ENOG4105BZE flagellar hook protein, FlgE BGM07_001410 ENOG4108KPB Flagellar basal-body rod protein FlgF BGM07_001415 ENOG4105CGA flagellar basal-body rod protein FlgG BGM07_001420 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BGM07_001425 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BGM07_001430 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BGM07_001435 ENOG4105E1Q flagellar hook-associated protein BGM07_001440 ENOG4105DTJ flagellar hook-associated protein BGM07_001465 ENOG4106UJV Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity) BGM07_001490 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BGM07_001495 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) BGM07_001500 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BGM07_001515 ENOG4105N14 lysine exporter protein LysE YggA BGM07_001535 ENOG4107Z3H Transcriptional regulator, TetR family BGM07_001545 ENOG4105CGH 5'-nucleotidase BGM07_001550 ENOG4105EA8 2-Nitropropane dioxygenase BGM07_001555 ENOG4105CWX Alpha-1,2-mannosidase BGM07_001560 ENOG4105CWX Alpha-1,2-mannosidase BGM07_001570 ENOG4105CWX Alpha-1,2-mannosidase BGM07_001575 ENOG4105CWX Alpha-1,2-mannosidase BGM07_001580 ENOG4105DM4 PTS System BGM07_001590 ENOG4108F19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BGM07_001595 ENOG4105KHA Glyoxalase Bleomycin resistance protein (Dioxygenase BGM07_001600 ENOG4105N2W Transcriptional regulator BGM07_001625 ENOG4108RWI nicotinamidase BGM07_001635 ENOG4107RH7 Nicotinate phosphoribosyltransferase BGM07_001660 ENOG4105ETT transcriptional Regulator, LysR family BGM07_001675 ENOG4105RW8 MltA-interacting MipA family protein BGM07_001680 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion BGM07_001690 ENOG4105VYW UPF0251 protein BGM07_001715 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BGM07_001725 ENOG4107S8C mandelate racemase muconate lactonizing BGM07_001735 ENOG4105RQF LysR family Transcriptional regulator BGM07_001750 ENOG4108Z4X TRANSCRIPTIONal BGM07_001780 ENOG4107RZC phospholipase d BGM07_001830 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BGM07_001870 ENOG41086KC Transcriptional regulator BGM07_001880 ENOG4105BZU Histidine kinase BGM07_001900 ENOG4107KET secretion protein, HlyD family BGM07_001915 ENOG4107RUE extracellular solute-binding protein family 1 BGM07_001920 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BGM07_001935 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BGM07_001940 ENOG4105CF9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity) BGM07_001945 ENOG4105HDK L-asparaginase BGM07_001950 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BGM07_001970 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme BGM07_001980 ENOG4108ZX5 transcriptional regulator BGM07_001985 ENOG4105CHR reductase BGM07_001995 ENOG4105CPQ Dehydrogenase BGM07_002000 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BGM07_002015 ENOG4107RSM transcriptional regulator BGM07_002025 ENOG4105C1J atp-dependent rna helicase BGM07_002050 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BGM07_002055 ENOG410874W AraC family transcriptional regulator BGM07_002075 ENOG4108P3C BGM07_002090 ENOG4105CHR reductase BGM07_002110 ENOG4105NAE bifunctional deaminase-reductase domain protein BGM07_002120 ENOG4105CYM Glutathione S-transferase BGM07_002135 ENOG4105DZ1 carboxypeptidase BGM07_002160 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) BGM07_002175 ENOG4105VEQ Cold shock protein BGM07_002180 ENOG4105EUB pirin domain protein BGM07_002185 ENOG4108NRW Phospholipase, patatin family BGM07_002195 ENOG4108T3F Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes BGM07_002220 ENOG4105EP9 oxidoreductase BGM07_002225 ENOG4105DIJ Phosphoethanolamine transferase BGM07_002230 ENOG41080IJ Diacylglycerol kinase BGM07_002240 ENOG4105JJR Histidine kinase BGM07_002245 ENOG4107EXC regulatoR BGM07_002250 ENOG4105EMU Dehydrogenase BGM07_002265 ENOG4108Z33 Thiol disulfide Interchange Protein BGM07_002285 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) BGM07_002295 ENOG4108J8Q Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity) BGM07_002305 ENOG4105EST Metal Dependent Phosphohydrolase BGM07_002315 ENOG4105DZC cytosine deaminase BGM07_002320 ENOG4105DQW permease for cytosine purines, uracil, thiamine, allantoin BGM07_002325 ENOG4105CJW magnesium transporter BGM07_002330 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) BGM07_002345 ENOG4105DVH amino acid BGM07_002350 ENOG4108XM1 transcriptional regulator AsnC family BGM07_002355 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) BGM07_002375 ENOG4105BZU Histidine kinase BGM07_002380 ENOG4105EE0 oxidoreductase BGM07_002390 ENOG41090HJ UPF0265 protein BGM07_002400 ENOG4108YXG UPF0502 protein BGM07_002405 ENOG41082IR Excinuclease ABC C subunit domain protein BGM07_002410 ENOG4108QGH periplasmic BGM07_002415 ENOG4105BZU Histidine kinase BGM07_002425 ENOG4105EFX secretion protein, HlyD family BGM07_002445 ENOG4105EW9 transcriptional regulator AsnC family BGM07_002475 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BGM07_002480 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BGM07_002490 ENOG410829K Lysine exporter protein (Lyse ygga) BGM07_002500 ENOG4105CHU acetyl-coa acetyltransferase BGM07_002510 ENOG4105D1N poly(r)-hydroxyalkanoic acid synthase, class BGM07_002520 ENOG4105CUW cytochrome C-TYPE protein BGM07_002530 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BGM07_002545 ENOG4105BZU Histidine kinase BGM07_002550 ENOG4105WH1 Two component transcriptional regulator luxr family BGM07_002565 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BGM07_002570 ENOG4107YWA deoxycytidylate deaminase BGM07_002585 ENOG4108N3W hemolysin secretion protein BGM07_002590 ENOG4108YZN class I peptide chain release factor BGM07_002595 ENOG4107VXZ Hydrolase BGM07_002600 ENOG4105UYK outer membrane protein a BGM07_002605 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BGM07_002610 ENOG4105DXI Major Facilitator superfamily BGM07_002615 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BGM07_002620 ENOG4105CV1 Transketolase (EC 2.2.1.1) BGM07_002625 ENOG4105CW3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BGM07_002650 ENOG4105BZU Histidine kinase BGM07_002655 ENOG4105KHC sulfurtransferase BGM07_002670 ENOG4105D06 uba thif-type nad fad binding protein BGM07_002675 ENOG4105CVM Molybdenum cofactor synthesis domain protein BGM07_002685 ENOG4105C5A transporter BGM07_002695 ENOG4105CMQ Chloride channel BGM07_002710 ENOG4107RGM aldo keto reductase BGM07_002715 ENOG4108UNF response regulator BGM07_002725 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BGM07_002730 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BGM07_002735 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BGM07_002740 ENOG4105C10 Electron transfer flavoprotein BGM07_002745 ENOG4105BZJ Electron transfer flavoprotein BGM07_002750 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase BGM07_002760 ENOG4105C0Z ABC transporter BGM07_002785 ENOG4108IV0 ABC, transporter BGM07_002790 ENOG4105DZS Phenylacetate-CoA ligase BGM07_002805 ENOG4105G9V cytochrome C BGM07_002815 ENOG4105VUF Transcriptional regulator BGM07_002820 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BGM07_002825 ENOG4108S58 Phenazine biosynthesis protein PhzF BGM07_002835 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BGM07_002840 ENOG4105C4M (Ubiquinol oxidase) subunit I BGM07_002845 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BGM07_002850 ENOG4108UW5 maltose o-acetyltransferase BGM07_002855 ENOG4105EGS Mechanosensitive ion channel BGM07_002870 ENOG4105BZU Histidine kinase BGM07_002875 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BGM07_002880 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BGM07_002885 ENOG4108IPT Naphthoate synthase BGM07_002890 ENOG4107QX3 carboxylase BGM07_002895 ENOG4105C1G acyl-Coa dehydrogenase BGM07_002905 ENOG4105CHU acetyl-coa acetyltransferase BGM07_002910 ENOG4105C26 Dehydrogenase BGM07_002915 ENOG4105C1G acyl-Coa dehydrogenase BGM07_002920 ENOG4105E39 Enoyl-CoA hydratase BGM07_002930 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BGM07_002945 ENOG4105BZU Histidine kinase BGM07_002950 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) BGM07_002955 ENOG4105C26 Dehydrogenase BGM07_002960 ENOG4105CZ6 Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity) BGM07_002970 ENOG4108HQS Glycine betaine BGM07_002975 ENOG4108IJ7 Glycine betaine BGM07_002980 ENOG4108RCM Nitroreductase BGM07_002990 ENOG4107QX8 SPFH domain, Band 7 family protein BGM07_003000 ENOG4105BZU Histidine kinase BGM07_003005 ENOG4105CA0 peroxidase BGM07_003010 ENOG4105BZU Histidine kinase BGM07_003070 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BGM07_003075 ENOG4108K0B C-di-gmp phosphodiesterase BGM07_003080 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BGM07_003085 ENOG4105C2J ABC transporter BGM07_003090 ENOG4105CNN ABC, transporter BGM07_003095 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BGM07_003100 ENOG4108RVA ribokinase BGM07_003105 ENOG4105ETE Transcriptional regulator (LacI family BGM07_003115 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BGM07_003120 ENOG4108I5U Uridine phosphorylase BGM07_003135 ENOG4105DHS permease protein BGM07_003140 ENOG4105CM4 permease protein BGM07_003145 ENOG4108IPW abc transporter atp-binding protein BGM07_003150 ENOG4108Z6Z Transcriptional regulator BGM07_003165 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BGM07_003200 ENOG4105EM2 membrane BGM07_003205 ENOG41088T4 Helicase IV BGM07_003210 ENOG4108Z5K methylglyoxal synthase BGM07_003215 ENOG4108SV3 Tmao reductase system periplasmic protein tort BGM07_003220 ENOG4105BZU Histidine kinase BGM07_003235 ENOG4105E3W Two component transcriptional regulator (Winged helix family BGM07_003245 ENOG4105ENH Sulfatase BGM07_003250 ENOG4105ENH Sulfatase BGM07_003265 ENOG4105ENH Sulfatase BGM07_003270 ENOG4105C4X radical SAM domain protein BGM07_003275 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BGM07_003305 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BGM07_003310 ENOG41064T2 transcriptional regulator, lysR family BGM07_003315 ENOG4107TE5 Lipid kinase BGM07_003320 ENOG4108YDI single-species biofilm formation on inanimate substrate BGM07_003340 ENOG4105C4X radical SAM domain protein BGM07_003350 ENOG4105F2V VRR-NUC domain-containing protein BGM07_003365 ENOG4105D0M Protease HtpX homolog BGM07_003370 ENOG4108V0P LemA family BGM07_003375 ENOG4105CEE C4-dicarboxylate transporter BGM07_003395 ENOG4108MGY Histidine kinase BGM07_003400 ENOG4107KBT 8-Amino-7-oxononanoate synthase BGM07_003405 ENOG4105C9W Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity) BGM07_003415 ENOG4105KXC Collagenase BGM07_003425 ENOG4106R3P AraC family transcriptional regulator BGM07_003500 ENOG4105CDV Ompa motb domain protein BGM07_003510 ENOG4108WAV Transcriptional regulator BGM07_003515 ENOG41064T2 transcriptional regulator, lysR family BGM07_003525 ENOG4105BZU Histidine kinase BGM07_003530 ENOG4105BZU Histidine kinase BGM07_003535 ENOG4108WQH regulatoR BGM07_003540 ENOG4105BZU Histidine kinase BGM07_003550 ENOG4108WQH regulatoR BGM07_003570 ENOG4107R88 Chemotaxis protein (CheV) BGM07_003585 ENOG4105FR1 rard protein BGM07_003595 ENOG4106CKV Pap2 superfamily protein BGM07_003605 ENOG4105D4Y metalloprotease BGM07_003615 ENOG4108I0N Transporter, RarD family, DMT superfamily protein BGM07_003635 ENOG4107RGH Aldehyde dehydrogenase BGM07_003640 ENOG4107QPK )-transporter BGM07_003645 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BGM07_003650 ENOG4106YYS transcriptional regulatory protein BGM07_003660 ENOG4105CBC glutamate synthase BGM07_003670 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) BGM07_003695 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BGM07_003700 ENOG4108UYE Lactoylglutathione lyase BGM07_003720 ENOG4105CJW magnesium transporter BGM07_003740 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BGM07_003760 ENOG4105HDD phospholipase BGM07_003785 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BGM07_003790 ENOG4105CR8 Transcriptional regulator BGM07_003865 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BGM07_003875 ENOG4105CBI The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor BGM07_003880 ENOG4105KE9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity) BGM07_003885 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BGM07_003925 ENOG4105DM4 PTS System BGM07_003930 ENOG4105DE4 1-phosphofructokinase BGM07_003935 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein BGM07_003940 ENOG4107B7Y DNA-binding transcriptional regulator FruR BGM07_003960 ENOG4108NJZ Sensory box GGDEF EAL domain protein BGM07_003965 ENOG4105DRP amino acid AbC transporter BGM07_003970 ENOG4106TNF Periplasmic binding protein BGM07_003975 ENOG4105E5Q amino acid AbC transporter BGM07_003980 ENOG4105CDA abc transporter atp-binding protein BGM07_003985 ENOG4105CA9 Pyruvate kinase BGM07_003990 ENOG4105CXY transporter BGM07_003995 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC BGM07_004005 ENOG4107TXD phosphoglycerate transport system transcriptional regulatory protein pgta BGM07_004015 ENOG4108I6A alcohol dehydrogenase BGM07_004020 ENOG4105CF7 AraC family transcriptional regulator BGM07_004035 ENOG4107QQ4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BGM07_004040 ENOG4105CKU formyltetrahydrofolate synthetase BGM07_004045 ENOG4107RE1 Inosine-guanosine kinase BGM07_004060 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase BGM07_004065 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BGM07_004085 ENOG4108ZYK Acyl carrier protein phosphodiesterase BGM07_004090 ENOG4105C1J atp-dependent rna helicase BGM07_004095 ENOG4108M8H domain protein BGM07_004110 ENOG4105DS1 cytochrome b561 BGM07_004115 ENOG4108YYC ycei family BGM07_004120 ENOG4105TMB Formate nitrite transporter BGM07_004125 ENOG4105DUM transcriptional regulator, lysR family BGM07_004130 ENOG4108UQ5 membrane protein YcdZ BGM07_004135 ENOG4105CPB ATP-dependent endonuclease of the OLD family BGM07_004140 ENOG4105CGH 5'-nucleotidase BGM07_004145 ENOG4105DU1 integral membrane protein, terc BGM07_004160 ENOG4108M0H Extracellular lipase BGM07_004165 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BGM07_004180 ENOG4105KA0 thioesterase Superfamily protein BGM07_004190 ENOG4105KNR Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity) BGM07_004215 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) BGM07_004225 ENOG4105BZU Histidine kinase BGM07_004230 ENOG4105RKW reductase (By BGM07_004240 ENOG4108I0Y (ABC) transporter BGM07_004245 ENOG4105CV6 ABC transporter, permease BGM07_004255 ENOG4107R7A Allophanate hydrolase subunit 2 BGM07_004260 ENOG4105P4J Allophanate hydrolase, subunit 1 BGM07_004265 ENOG4105E7W lamb ycsf family protein BGM07_004270 ENOG4105BZU Histidine kinase BGM07_004275 ENOG4105CMR udp-glucose 4-epimerase BGM07_004290 ENOG4105CWB LysR family transcriptional Regulator BGM07_004295 ENOG4105CD5 CoA-binding domain protein BGM07_004305 ENOG4105CPF Cell wall formation (By similarity) BGM07_004315 ENOG4108ZJT translation initiation factor, Sui1 BGM07_004470 ENOG4105EJC lysr family transcriptional regulator BGM07_004480 ENOG4108M6U Universal stress protein A BGM07_004510 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BGM07_004515 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BGM07_004530 ENOG4105BZU Histidine kinase BGM07_004550 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) BGM07_004555 ENOG4105E0C molybdate abc transporter BGM07_004560 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BGM07_004565 ENOG4105CAA catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity) BGM07_004570 ENOG4105WXI Bacterial OB fold (BOF) protein BGM07_004580 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) BGM07_004585 ENOG4105CGF Aromatic amino acid aminotransferase BGM07_004590 ENOG4105ECQ AraC Family Transcriptional Regulator BGM07_004595 ENOG4107QI1 Mate efflux family protein BGM07_004600 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BGM07_004605 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BGM07_004620 ENOG4105BZS acriflavin resistance protein BGM07_004650 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit BGM07_004660 ENOG4105C5Q Transcriptional regulator BGM07_004665 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BGM07_004670 ENOG4105CXY transporter BGM07_004675 ENOG4108KX4 response regulator BGM07_004680 ENOG4105BZU Histidine kinase BGM07_004685 ENOG4105CXY transporter BGM07_004690 ENOG4105EIP mannose-6-phosphate isomerase BGM07_004710 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BGM07_004715 ENOG4105K63 Thioredoxin BGM07_004720 ENOG4108ISG Major Facilitator BGM07_004730 ENOG4107QI1 Mate efflux family protein BGM07_004735 ENOG4105VXR cytoplasmic protein BGM07_004765 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BGM07_004780 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BGM07_004785 ENOG4105TMB Formate nitrite transporter BGM07_004790 ENOG4105WZK nitrite reductase NADPH small subunit BGM07_004795 ENOG4107QZF nitrite reductase NADPH large subunit BGM07_004800 ENOG4105NXH GreA GreB family elongation factor BGM07_004840 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) BGM07_004875 ENOG4108NVR Methyl-accepting chemotaxis BGM07_004880 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BGM07_004900 ENOG4105CXG d-lactate dehydrogenase BGM07_004905 ENOG4105CC0 LysR family Transcriptional regulator BGM07_004920 ENOG4105EV2 VWA domain protein interacting with AAA ATPase BGM07_004925 ENOG4107R4Q Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity) BGM07_004930 ENOG4107VIJ nudix hydrolase BGM07_004935 ENOG4105C5W Aldolase BGM07_004940 ENOG4106RE7 Cytochrome BGM07_004945 ENOG4105CSX c4-dicarboxylate anaerobic carrier BGM07_004955 ENOG4105C2C drug resistance transporter, Bcr CflA BGM07_004965 ENOG4105QNF Outer membrane lipoprotein BGM07_004985 ENOG4105EYH Exonuclease BGM07_004990 ENOG4107RFY SbcCD D subunit BGM07_005015 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BGM07_005060 ENOG4108ZF3 Phosphatase BGM07_005075 ENOG4106VK6 Flagellar motor protein BGM07_005100 ENOG4105D9P serine threonine protein kinase BGM07_005120 ENOG4105F8J Adenylate Guanylate cyclase BGM07_005135 ENOG4108IG5 Transcriptional regulator BGM07_005150 ENOG4107QZF nitrite reductase NADPH large subunit BGM07_005155 ENOG4105D7T ABC transporter BGM07_005160 ENOG4105DG7 nitrate ABC transporter BGM07_005165 ENOG4105D7T ABC transporter BGM07_005190 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BGM07_005200 ENOG4108R6G acetyltransferase BGM07_005205 ENOG4105C44 Serine transporter BGM07_005215 ENOG4105BZU Histidine kinase BGM07_005235 ENOG4105G6Z alkaline phosphatase BGM07_005250 ENOG4105ETX regulatoR BGM07_005275 ENOG4106E5D Protein of unknown function (DUF461) BGM07_005280 ENOG4105R8A Heat shock protein BGM07_005295 ENOG4107RUY (E1 component), alpha subunit BGM07_005300 ENOG4105CPP Dehydrogenase, E1 component BGM07_005305 ENOG4107QSN dihydrolipoamide acetyltransferase BGM07_005310 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase BGM07_005315 ENOG4107MKT Stringent starvation protein a BGM07_005320 ENOG4105DUM transcriptional regulator, lysR family BGM07_005330 ENOG4105DMR ABC, transporter BGM07_005335 ENOG4105GBT ABC transporter BGM07_005340 ENOG4106PMH Extracellular solute-binding protein family 3 BGM07_005345 ENOG4105E5Z arginine transporter ATP-binding subunit BGM07_005355 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BGM07_005365 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BGM07_005375 ENOG4105CCU oxidase (Subunit III) BGM07_005380 ENOG4105BZ9 Cytochrome C oxidase, subunit I BGM07_005385 ENOG4105E2S oxidase) subunit II BGM07_005390 ENOG4105CHR reductase BGM07_005395 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BGM07_005400 ENOG4105E39 Enoyl-CoA hydratase BGM07_005405 ENOG4105E39 Enoyl-CoA hydratase BGM07_005415 ENOG4105C26 Dehydrogenase BGM07_005420 ENOG4105CHU acetyl-coa acetyltransferase BGM07_005430 ENOG4105C1G acyl-Coa dehydrogenase BGM07_005435 ENOG4107QX3 carboxylase BGM07_005440 ENOG4105CGU Enoyl-CoA hydratase BGM07_005445 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase BGM07_005460 ENOG4107SDU Methyl-accepting chemotaxis BGM07_005465 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BGM07_005475 ENOG4105BZU Histidine kinase BGM07_005480 ENOG4105C1J atp-dependent rna helicase BGM07_005485 ENOG4108ENQ Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity) BGM07_005500 ENOG4107S17 Phosphate-binding protein BGM07_005520 ENOG4105C4X radical SAM domain protein BGM07_005525 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) BGM07_005530 ENOG4105DUM transcriptional regulator, lysR family BGM07_005540 ENOG4108N3W hemolysin secretion protein BGM07_005545 ENOG4105DKW ABC transporter BGM07_005550 ENOG4105CXC rtn protein BGM07_005570 ENOG4105C1J atp-dependent rna helicase BGM07_005575 ENOG4105CKI cobalamin synthesis protein BGM07_005585 ENOG4108KN7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity) BGM07_005595 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BGM07_005600 ENOG4105VYA Uncharacterized conserved protein (DUF2132) BGM07_005605 ENOG4105C1J atp-dependent rna helicase BGM07_005610 ENOG4105VRT cytoplasmic protein BGM07_005630 ENOG41090A4 Pterin carbinolamine dehydratase BGM07_005635 ENOG4105MIR Phenylalanine 4-monooxygenase BGM07_005640 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BGM07_005645 ENOG4107RFD Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BGM07_005680 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain BGM07_005685 ENOG4105C0A alcohol dehydrogenase BGM07_005700 ENOG4108RMU ferritin dps family protein BGM07_005705 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_005715 ENOG4107R39 (ABC) transporter BGM07_005735 ENOG4105BZU Histidine kinase BGM07_005745 ENOG4107SDU Methyl-accepting chemotaxis BGM07_005755 ENOG4105VEQ Cold shock protein BGM07_005785 ENOG4108V1T peptidylprolyl cis-trans isomerase BGM07_005790 ENOG4105F1R Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity) BGM07_005795 ENOG4107TQK Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity) BGM07_005815 ENOG4107QS1 Cytochrome C Oxidase, Subunit III BGM07_005820 ENOG4105FT1 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity) BGM07_005850 ENOG4105SUT Transcriptional Regulator AraC Family BGM07_005880 ENOG4108SXK Transporter Drug Metabolite Exporter family BGM07_005885 ENOG4105VW4 glutaredoxin 3 BGM07_005905 ENOG4105E5M Multidrug resistance protein D BGM07_005910 ENOG4105CR8 Transcriptional regulator BGM07_005920 ENOG4105DR5 peptidase BGM07_005940 ENOG4105DWD nucleoside recognition domain protein BGM07_005945 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_005955 ENOG4105E0U tyrosine-specific transport protein BGM07_005980 ENOG4107Z1W Fructose transport system kinase BGM07_005990 ENOG4105DXH Alcohol dehydrogenase zinc-binding domain protein BGM07_005995 ENOG4105CTS PTS system mannitol-specific BGM07_006000 ENOG4108X7Y Mannitol-specific cryptic phosphotransferase enzyme iia BGM07_006020 ENOG4105D6J arsenicaL-resistance protein BGM07_006030 ENOG4108V1U phospholipid-binding protein BGM07_006035 ENOG4105JAB phenazine biosynthesis protein, phzf family BGM07_006040 ENOG4105HHQ 6-phosphogluconolactonase (EC 3.1.1.31) BGM07_006050 ENOG4108NVR Methyl-accepting chemotaxis BGM07_006060 ENOG4105CJ1 ABC, transporter BGM07_006065 ENOG4107QWP ABC-2 type transporter BGM07_006080 ENOG4108IEG Formate dehydrogenase Alpha subunit BGM07_006105 ENOG4108IJF Heavy metal efflux pump, CzcA BGM07_006125 ENOG410620I Diguanylate cyclase BGM07_006135 ENOG4108HK0 -acetyltransferase BGM07_006145 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BGM07_006155 ENOG4105ENT Efflux transporter rnd family, mfp subunit BGM07_006170 ENOG4105C5H ABC transporter BGM07_006175 ENOG4108M6U Universal stress protein A BGM07_006180 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BGM07_006185 ENOG4105CKD glutathione-regulated potassium-efflux system protein BGM07_006210 ENOG4105KXC Collagenase BGM07_006225 ENOG4105C5Q Transcriptional regulator BGM07_006240 ENOG4105C1X Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity) BGM07_006280 ENOG4105CNH Multidrug resistance protein MdtL BGM07_006285 ENOG4105G2Y Transcriptional regulator BGM07_006295 ENOG4105KQ5 peptidylprolyl cis-trans isomerase BGM07_006305 ENOG4107R88 Chemotaxis protein (CheV) BGM07_006315 ENOG4105PYN Pyridoxamine 5-phosphate oxidase-related BGM07_006320 ENOG41090JE Utilization Protein BGM07_006325 ENOG4105D4P Coproporphyrinogen iii oxidase BGM07_006330 ENOG4105WQ5 TonB family BGM07_006335 ENOG41090AP transport protein BGM07_006340 ENOG4106GFD transport protein BGM07_006350 ENOG4105EHG Permease protein BGM07_006355 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) BGM07_006400 ENOG4107X4V Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity) BGM07_006405 ENOG4107RA1 nh(3)-dependent nad( ) synthetase BGM07_006410 ENOG4105QVC MOSC domain-containing protein BGM07_006410 ENOG4105QVC MOSC domain-containing protein BGM07_006430 ENOG4105EKE dihydroorotase BGM07_006435 ENOG4105CKW Inner membrane protein yedI BGM07_006550 ENOG4105CQM Urea amidohydrolase subunit alpha BGM07_006570 ENOG4105DEF Extracellular solute-binding protein, family 5 BGM07_006580 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BGM07_006585 ENOG4108JQ6 ABC transporter BGM07_006595 ENOG4108MIW Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions BGM07_006630 ENOG4105DWP Membrane BGM07_006690 ENOG4105K44 type iii secretion BGM07_006705 ENOG41075IY surface presentation of antigens protein SpaP BGM07_006720 ENOG4108TU9 TRANSCRIPTIONal BGM07_006865 ENOG4105BZU Histidine kinase BGM07_007000 ENOG4105EG2 ABC transporter, permease BGM07_007005 ENOG4105D56 permease protein BGM07_007010 ENOG4107FKK extracellular solute-binding protein family 1 BGM07_007015 ENOG4108IJ9 (ABC) transporter BGM07_007035 ENOG4105D75 Capsular exopolysaccharide family BGM07_007075 ENOG4105V0I UPF0267 protein BGM07_007080 ENOG4108WUH Transcriptional regulator, TetR family BGM07_007085 ENOG4105CJH Alcohol dehydrogenase zinc-binding domain protein BGM07_007090 ENOG4108RXX maleylacetoacetate isomerase BGM07_007095 ENOG4105CH6 catalase BGM07_007100 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase BGM07_007105 ENOG4105DM4 PTS System BGM07_007110 ENOG4108YRF PTS System BGM07_007120 ENOG4106R3P AraC family transcriptional regulator BGM07_007125 ENOG4105DM4 PTS System BGM07_007130 ENOG4105EIP mannose-6-phosphate isomerase BGM07_007140 ENOG4105MN5 HAD-superfamily hydrolase subfamily IA variant 3 BGM07_007150 ENOG4105BZU Histidine kinase BGM07_007155 ENOG4105CZN Potassium uptake protein BGM07_007170 ENOG4105BZU Histidine kinase BGM07_007175 ENOG4105BZ1 (ABC) transporter BGM07_007180 ENOG4105E0K tonB-dependent siderophore receptor BGM07_007185 ENOG4105E0A ABC, transporter BGM07_007190 ENOG4108HUF Transporter BGM07_007195 ENOG4105S6R Iron-hydroxamate transporter permease subunit BGM07_007205 ENOG4105KCK Peptidoglycan-associated lipoprotein BGM07_007225 ENOG4108JJ6 Type I secretion system ATPase BGM07_007235 ENOG41086KC Transcriptional regulator BGM07_007240 ENOG41086KC Transcriptional regulator BGM07_007250 ENOG41069D7 Methyl-accepting chemotaxis BGM07_007255 ENOG4105C7R Atpase associated with various cellular activities aaa_3 BGM07_007275 ENOG4107QVM von Willebrand factor, type A BGM07_007290 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BGM07_007295 ENOG4105E2Z phosphate ABC transporter (Permease BGM07_007300 ENOG4105C8U phosphate abc transporter BGM07_007305 ENOG4107S17 Phosphate-binding protein BGM07_007310 ENOG4108NVR Methyl-accepting chemotaxis BGM07_007330 ENOG4105D05 Receptor BGM07_007335 ENOG4105CUG Oligopeptidase b BGM07_007340 ENOG4105C1J atp-dependent rna helicase BGM07_007350 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BGM07_007355 ENOG4105CVP deoxyribo-dipyrimidine photolyase BGM07_007360 ENOG4108XDN Transcriptional regulator BGM07_007365 ENOG4107SEY Conserved Protein BGM07_007370 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BGM07_007385 ENOG4106TD9 Diguanylate cyclase BGM07_007390 ENOG4105KK7 inner membrane protein YiaW BGM07_007395 ENOG4105EFX secretion protein, HlyD family BGM07_007400 ENOG4108V7D UPF0397 protein BGM07_007405 ENOG4108JJB ABC transporter BGM07_007420 ENOG4105GXZ Ferredoxin-type protein NapH BGM07_007425 ENOG4108BGM Quinol dehydrogenase periplasmic component BGM07_007430 ENOG4105WCN acetyltransferase BGM07_007445 ENOG4105YE1 PilZ domain BGM07_007450 ENOG4108NVR Methyl-accepting chemotaxis BGM07_007455 ENOG4105DAN ATP-dependent protease BGM07_007465 ENOG4108JQ5 ABC transporter BGM07_007475 ENOG4105CR8 Transcriptional regulator BGM07_007480 ENOG4105DAA L-lactate BGM07_007485 ENOG4105DMF Dehydrogenase BGM07_007495 ENOG4105D64 Mechanosensitive ion channel BGM07_007530 ENOG4105CPQ Dehydrogenase BGM07_007535 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BGM07_007540 ENOG4105BZU Histidine kinase BGM07_007545 ENOG4107R0W ABC transporter BGM07_007555 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BGM07_007565 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGM07_007590 ENOG4105EXG Transcriptional regulator BGM07_007595 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BGM07_007615 ENOG4107SSZ Phosphatase BGM07_007645 ENOG4108JIR Flagellum-specific ATP synthase BGM07_007655 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BGM07_007660 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BGM07_007670 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM07_007685 ENOG4105DD5 Flagellar motor switch protein BGM07_007690 ENOG4105CN7 Flagellar biosynthetic protein FliP BGM07_007695 ENOG4105VS8 Flagellar biosynthetic protein fliq BGM07_007700 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BGM07_007705 ENOG4105D00 flagellar biosynthetic protein flhB BGM07_007720 ENOG4105I03 Flagellin BGM07_007740 ENOG410804A Flagellar hook-associated 2 domain-containing protein BGM07_007745 ENOG4105MQ3 flagellar protein FliS BGM07_007770 ENOG4107RD7 Flagellar Motor Protein, MotA BGM07_007775 ENOG4105ER2 Ompa motb domain protein BGM07_007785 ENOG4105KWG Pfam:DUF1696 BGM07_007820 ENOG4105C6N Formate acetyltransferase BGM07_007825 ENOG4105F1A Pyruvate formate-lyase BGM07_007830 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BGM07_007840 ENOG4105I4A GCN5-related N-acetyltransferase BGM07_007855 ENOG4105CNH Multidrug resistance protein MdtL BGM07_007860 ENOG4105G2Y Transcriptional regulator BGM07_007900 ENOG4105IPI Membrane BGM07_007905 ENOG41068P6 UPF0319 protein BGM07_007915 ENOG4105DP0 ferredoxin-NADP reductase BGM07_007925 ENOG4105VYA Uncharacterized conserved protein (DUF2132) BGM07_007930 ENOG4105ETT transcriptional Regulator, LysR family BGM07_007940 ENOG4108RCM Nitroreductase BGM07_007945 ENOG4108ZX5 transcriptional regulator BGM07_007955 ENOG4105DZ1 carboxypeptidase BGM07_007970 ENOG4105C72 UPF0176 protein BGM07_007975 ENOG4108M1A Chitin-binding protein BGM07_007980 ENOG4108NRW Phospholipase, patatin family BGM07_007985 ENOG41081FY multiple antibiotic resistance (MarC)-related BGM07_008000 ENOG4105DAY polysaccharide export protein BGM07_008005 ENOG4107ZF2 Phosphatase BGM07_008020 ENOG4105N0V mono-oxygenase ydhR BGM07_008025 ENOG4105F04 LysR family Transcriptional regulator BGM07_008035 ENOG4105CK2 sodium dicarboxylate symporter BGM07_008045 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) BGM07_008050 ENOG4108P2H Inner membrane protein YjiG BGM07_008055 ENOG41074DU domain protein BGM07_008070 ENOG4107T9C Alpha amylase catalytic region BGM07_008075 ENOG4108VKV Monofunctional biosynthetic peptidoglycan transglycosylase BGM07_008080 ENOG4105C9C Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity) BGM07_008085 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) BGM07_008090 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BGM07_008100 ENOG41061ZR Transcriptional regulator BGM07_008130 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BGM07_008135 ENOG4107QV7 Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity) BGM07_008145 ENOG4107XGF functions in a salvage pathway. Uses pyridoxamine (By similarity) BGM07_008155 ENOG4105D5Q Arginine ornithine antiporter BGM07_008160 ENOG4105CXN decarboxylase BGM07_008180 ENOG4108K8S endonuclease I BGM07_008200 ENOG4108KDD Involved in the transport of maltose and maltodextrins (By similarity) BGM07_008225 ENOG4105DR5 peptidase BGM07_008235 ENOG4107RAN Peptidase, M16 BGM07_008240 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_008245 ENOG4105E0A ABC, transporter BGM07_008250 ENOG4108U1V ABC transporter, permease BGM07_008255 ENOG4105DQ5 transport system permease protein BGM07_008260 ENOG4108HUF Transporter BGM07_008265 ENOG4105GAV receptor BGM07_008270 ENOG4105E0K tonB-dependent siderophore receptor BGM07_008280 ENOG4105DUU IucA IucC family protein BGM07_008290 ENOG4105DBM Siderophore biosynthesis protein BGM07_008295 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BGM07_008300 ENOG4108JP0 extracellular solute-binding protein family 1 BGM07_008305 ENOG4105DHQ Histidine kinase BGM07_008310 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGM07_008315 ENOG4105CI1 PTS System BGM07_008345 ENOG4105CKK Glycosyl transferase, family 2 BGM07_008365 ENOG4108ZHJ Organic hydroperoxide resistance protein BGM07_008370 ENOG4105K56 Transcriptional regulator BGM07_008375 ENOG4105D3R alkyl hydroperoxide reductase BGM07_008380 ENOG4108JU3 Alkyl hydroperoxide reductase BGM07_008395 ENOG4105EXG Transcriptional regulator BGM07_008400 ENOG4105ECQ AraC Family Transcriptional Regulator BGM07_008405 ENOG4105DU6 RNA polymerase BGM07_008420 ENOG4108N3W hemolysin secretion protein BGM07_008425 ENOG4105W8I Transcriptional regulator BGM07_008430 ENOG4105F8D glycoside hydrolase family 4 BGM07_008445 ENOG4108RPX mosc domain containing protein BGM07_008450 ENOG4105C1J atp-dependent rna helicase BGM07_008465 ENOG4105CF7 AraC family transcriptional regulator BGM07_008475 ENOG4105BZ1 (ABC) transporter BGM07_008485 ENOG4105EW9 transcriptional regulator AsnC family BGM07_008520 ENOG4105CK7 Sodium proline symporter BGM07_008530 ENOG4105C26 Dehydrogenase BGM07_008550 ENOG4108S7T Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity) BGM07_008555 ENOG4105CQZ Histidine kinase BGM07_008560 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM07_008565 ENOG4107QZV Type I secretion membrane fusion protein BGM07_008580 ENOG4108JJA ABC, transporter BGM07_008675 ENOG4108J59 Extracellular solute-binding protein, family 5 BGM07_008685 ENOG4108PSC Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity) BGM07_008690 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BGM07_008695 ENOG4105C5Y PTS System BGM07_008700 ENOG4105FCK Membrane BGM07_008705 ENOG4105EC3 peptidase S51, dipeptidase E BGM07_008725 ENOG4105E0I Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity) BGM07_008730 ENOG4106RMF ParB family BGM07_008740 ENOG4105QTB Flavodoxin BGM07_008745 ENOG4105C1H Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity) BGM07_008750 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BGM07_008755 ENOG4105VAS Could be involved in insertion of integral membrane proteins into the membrane (By similarity) BGM07_008760 ENOG4105NVJ RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) BGM07_008775 ENOG4105E5Q amino acid AbC transporter BGM07_008780 ENOG4105EAB amino acid AbC transporter BGM07_008790 ENOG4105CI4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity) BGM07_008795 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BGM07_008800 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BGM07_008805 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BGM07_008820 ENOG4108ZNX Heat shock protein BGM07_008825 ENOG4105JKW Valine--pyruvate aminotransferase BGM07_008830 ENOG4107T9C Alpha amylase catalytic region BGM07_008835 ENOG4105C38 Glycyl-tRNA synthetase beta subunit BGM07_008840 ENOG4108HMW glycyl-tRNA synthetase, alpha subunit BGM07_008855 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) BGM07_008870 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family BGM07_008875 ENOG4105CHU acetyl-coa acetyltransferase BGM07_008880 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BGM07_008885 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BGM07_008890 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) BGM07_008895 ENOG4108RR8 protoporphyrinogen oxidase BGM07_008950 ENOG4105WMR Protein CrcB homolog BGM07_008955 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BGM07_008960 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) BGM07_008965 ENOG4105D06 uba thif-type nad fad binding protein BGM07_008970 ENOG4105WHD thiamine biosynthesis protein ThiS BGM07_008975 ENOG4105CA8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity) BGM07_008980 ENOG4105D41 biosynthesis protein thiH BGM07_008985 ENOG4105DC7 peptidase M24 BGM07_008985 ENOG4105DC7 peptidase M24 BGM07_009015 ENOG4105E18 UPF0276 protein BGM07_009025 ENOG4105C4R Atp-dependent dna helicase BGM07_009035 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) BGM07_009050 ENOG4105FR1 rard protein BGM07_009055 ENOG4105C9U ATP-dependent DNA helicase RecQ BGM07_009065 ENOG4105EX9 Membrane BGM07_009070 ENOG4105C9X ppx gppa phosphatase BGM07_009075 ENOG4105C1J atp-dependent rna helicase BGM07_009080 ENOG4105K63 Thioredoxin BGM07_009085 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) BGM07_009095 ENOG4105D3H Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity) BGM07_009100 ENOG4108ZIT Ferredoxin, 2FE-2S BGM07_009105 ENOG4107QK7 reductase BGM07_009155 ENOG410601J HemY protein BGM07_009160 ENOG4105ECF c-methyltransferase BGM07_009165 ENOG41076E6 Uroporphyrinogen-III Synthase BGM07_009170 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) BGM07_009175 ENOG4107T0K Adenylate cyclase BGM07_009180 ENOG4105XQ6 frataxin-like protein BGM07_009190 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BGM07_009195 ENOG4105E4Z Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity) BGM07_009205 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BGM07_009210 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant BGM07_009215 ENOG4105BZU Histidine kinase BGM07_009220 ENOG4106IUH DTW domain containing protein BGM07_009235 ENOG4105DQF Hydrolase BGM07_009240 ENOG4108EUD Lysophospholipase BGM07_009245 ENOG410829K Lysine exporter protein (Lyse ygga) BGM07_009250 ENOG4105D58 Diguanylate phosphodiesterase BGM07_009255 ENOG41082YX Transcriptional regulator, arsr family BGM07_009260 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BGM07_009315 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BGM07_009325 ENOG4106H78 methyltransferase BGM07_009330 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BGM07_009335 ENOG4105CAK Cell division ATP-binding protein ftsE BGM07_009340 ENOG4105CRP Part of the ABC transporter FtsEX involved in BGM07_009345 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGM07_009355 ENOG4105M78 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity) BGM07_009360 ENOG4105EBW Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity) BGM07_009365 ENOG4105X6C Flagellar basal body-associated protein FliL BGM07_009370 ENOG4105VEI Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity) BGM07_009375 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) BGM07_009380 ENOG4105E55 glycerol-3-phosphate acyltransferase BGM07_009390 ENOG4105DS7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity) BGM07_009400 ENOG4107R73 Mate efflux family protein BGM07_009405 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) BGM07_009420 ENOG4107R9T Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity) BGM07_009425 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) BGM07_009435 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) BGM07_009495 ENOG4105JIM Phosphatidylserine synthase BGM07_009505 ENOG4105D4A Cell wall formation (By similarity) BGM07_009510 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BGM07_009515 ENOG4105CS9 pantothenic acid kinase BGM07_009540 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BGM07_009550 ENOG4105PM1 preprotein translocase subunit SecE BGM07_009555 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BGM07_009560 ENOG4108UIK This protein binds directly to 23S ribosomal RNA (By similarity) BGM07_009565 ENOG4105C64 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity) BGM07_009570 ENOG4108VZM 50s ribosomal protein L10 BGM07_009575 ENOG4105KBC Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity) BGM07_009580 ENOG4108IIJ DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BGM07_009585 ENOG4105D27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BGM07_009590 ENOG4108ZVW Anti-RNA polymerase sigma 70 factor BGM07_009595 ENOG4105E09 nadh pyrophosphatase BGM07_009610 ENOG4105CFZ Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity) BGM07_009615 ENOG4108RG0 uracil-dna glycosylase BGM07_009620 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase BGM07_009625 ENOG4105R2J Conserved Protein BGM07_009645 ENOG4105C12 Phosphoribosylglycinamide synthetase BGM07_009650 ENOG4105DC1 bifunctional purine biosynthesis protein purh BGM07_009660 ENOG4105W1Y Transcriptional regulator BGM07_009665 ENOG4108M3R transcriptional activator CadC BGM07_009680 ENOG4105D5Q Arginine ornithine antiporter BGM07_009685 ENOG4105CXN decarboxylase BGM07_009750 ENOG4105BZU Histidine kinase BGM07_009755 ENOG4105C5H ABC transporter BGM07_009765 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BGM07_009770 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BGM07_009775 ENOG4105F59 Methylates ribosomal protein L11 (By similarity) BGM07_009780 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BGM07_009785 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BGM07_009790 ENOG4108Z38 Catalyzes a trans-dehydration via an enolate intermediate (By similarity) BGM07_009795 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BGM07_009810 ENOG4105D8G Major Facilitator superfamily BGM07_009815 ENOG4105BZU Histidine kinase BGM07_009820 ENOG4105C9Q fumarate hydratase class II BGM07_009835 ENOG4107QN1 sodium solute BGM07_009845 ENOG4105C3N Participates in control of cell volume in low-osmolarity conditions (By similarity) BGM07_009855 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) BGM07_009860 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BGM07_009865 ENOG4108IJ0 Aspartate ammonia-lyase BGM07_009870 ENOG4108YH1 overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7 BGM07_009875 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BGM07_009885 ENOG4105E0F Histidine kinase BGM07_009890 ENOG4105E3W Two component transcriptional regulator (Winged helix family BGM07_009895 ENOG4108SPG Periplasmic Protein BGM07_009900 ENOG41076HS cation diffusion facilitator family transporter BGM07_009905 ENOG4105CTQ phosphohexokinase BGM07_009910 ENOG4107QI1 Mate efflux family protein BGM07_009920 ENOG4105K5Y Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity) BGM07_009925 ENOG4105CJ9 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity) BGM07_009945 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BGM07_009950 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BGM07_009955 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BGM07_009965 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) BGM07_009970 ENOG4108WJH Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) BGM07_009975 ENOG4105E33 succinate dehydrogenase BGM07_009990 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) BGM07_010000 ENOG41062JF Transcriptional regulator BGM07_010010 ENOG41063SB peptidase BGM07_010015 ENOG4105D7W serine acetyltransferase BGM07_010020 ENOG4105CSF NADPH-dependent glycerol-3-phosphate dehydrogenase BGM07_010025 ENOG4105IX2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity) BGM07_010030 ENOG4107YZP Rhodanese domain protein BGM07_010035 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) BGM07_010045 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_010050 ENOG4105C8P )-transporter BGM07_010055 ENOG4105DJ4 phosphatidylserine decarboxylase BGM07_010060 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) BGM07_010065 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) BGM07_010135 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BGM07_010140 ENOG4105K8N protein family UPF0079, ATPase BGM07_010145 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BGM07_010150 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BGM07_010155 ENOG4105DKX Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity) BGM07_010160 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BGM07_010165 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BGM07_010170 ENOG4107QJR hflk protein BGM07_010175 ENOG4105EPW hflc protein BGM07_010185 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis BGM07_010190 ENOG4108UV7 flagellar protein motX BGM07_010195 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BGM07_010200 ENOG4105KPV Transcriptional regulator BGM07_010205 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BGM07_010210 ENOG4105C2N RNA methyltransferase TrmH family group 3 BGM07_010215 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BGM07_010220 ENOG4105C31 Tryptophanyl-tRNA synthetase BGM07_010235 ENOG4105DDQ anthranilate synthase BGM07_010240 ENOG4105C8Y Acetylornithine aminotransferase BGM07_010250 ENOG4105C26 Dehydrogenase BGM07_010260 ENOG4107RYR Transcriptional regulator, Crp Fnr family BGM07_010265 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) BGM07_010270 ENOG4105YP7 UPF0270 protein BGM07_010275 ENOG4105DNZ Alpha Beta Hydrolase BGM07_010285 ENOG4105C5H ABC transporter BGM07_010290 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein BGM07_010305 ENOG4108YZY peptidylprolyl cis-trans isomerase BGM07_010315 ENOG4105D44 asparaginase BGM07_010320 ENOG41069P5 Protein slyX homolog BGM07_010330 ENOG4108V1T peptidylprolyl cis-trans isomerase BGM07_010335 ENOG4105WWK YheO domain protein BGM07_010340 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) BGM07_010345 ENOG4108ZKU Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) BGM07_010350 ENOG4105YKK Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity) BGM07_010355 ENOG4108UKE Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity) BGM07_010360 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BGM07_010365 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BGM07_010370 ENOG4105CGV This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity) BGM07_010375 ENOG4105W53 bacterioferritin-associated ferredoxin BGM07_010380 ENOG4108UQY Iron-storage protein BGM07_010385 ENOG4105C6K Malic enzyme BGM07_010390 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) BGM07_010395 ENOG4105C28 cystathionine BGM07_010400 ENOG4105CFH Aspartokinase BGM07_010405 ENOG4105SYT Methylenetetrahydrofolate reductase BGM07_010415 ENOG4105CCA Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity) BGM07_010420 ENOG4105CWC Acetylornithine deacetylase BGM07_010425 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BGM07_010430 ENOG4105CAS nag kinase BGM07_010435 ENOG4105CDH Citrulline--aspartate ligase BGM07_010440 ENOG4105CH7 arginosuccinase BGM07_010455 ENOG4105EHV domain protein BGM07_010465 ENOG4108JQC penicillin-binding protein 1A BGM07_010490 ENOG4105E4G Type IV pilus BGM07_010495 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) BGM07_010500 ENOG4105D49 3-dehydroquinate synthase BGM07_010510 ENOG4105DFE Dna adenine methylase BGM07_010515 ENOG4105DJV ribulose-phosphate 3-epimerase BGM07_010520 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BGM07_010525 ENOG4108VDV Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity) BGM07_010530 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BGM07_010535 ENOG4105K9Q Binds to the 23S rRNA (By similarity) BGM07_010545 ENOG4105CDU Replicative dna helicase BGM07_010550 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BGM07_010560 ENOG4108YXI Secondary thiamine-phosphate synthase enzyme BGM07_010565 ENOG4107QP8 phosphohexose isomerase BGM07_010575 ENOG4105MYN Zinc uptake regulation protein BGM07_010580 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BGM07_010600 ENOG4107EER Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity) BGM07_010605 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) BGM07_010610 ENOG4105ET3 Reduction of activated sulfate into sulfite (By similarity) BGM07_010680 ENOG4105EEQ Na H antiporter BGM07_010750 ENOG4105EEQ Na H antiporter BGM07_010755 ENOG4105C3R Methionine synthase BGM07_010760 ENOG4105CFH Aspartokinase BGM07_010770 ENOG4105C5R Aminotransferase BGM07_010780 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BGM07_010785 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BGM07_010790 ENOG41086KC Transcriptional regulator BGM07_010795 ENOG4108UUM single-stranded DNA-binding protein BGM07_010800 ENOG41062P1 Diguanylate cyclase phosphodiesterase BGM07_010820 ENOG4105E4G Type IV pilus BGM07_010835 ENOG4107QHF type ii secretion system protein e BGM07_010840 ENOG4105D7Q type ii secretion system BGM07_010850 ENOG4108VAU general secretion pathway protein G BGM07_010885 ENOG4105DFF Rod shape-determining protein mreb BGM07_010890 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BGM07_010895 ENOG4105VQ7 Rod shape-determining protein MreD BGM07_010900 ENOG4108Z03 MAF-like protein BGM07_010905 ENOG4105C03 ribonuclease BGM07_010910 ENOG4105QD6 exported protein BGM07_010920 ENOG4105D1U peptidase U62 modulator of DNA gyrase BGM07_010925 ENOG4108IAB Phoh family BGM07_010930 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) BGM07_010935 ENOG4105K3M )-transporter BGM07_010945 ENOG4105D3G Pseudouridine synthase BGM07_010950 ENOG4105C5I Dehydrogenase BGM07_010955 ENOG4105N42 UPF0307 protein BGM07_010960 ENOG4105CMS peptidase U62, modulator of DNA gyrase BGM07_010965 ENOG4105CJW magnesium transporter BGM07_010970 ENOG41080Z8 PHOSPHOCARRIER protein BGM07_010975 ENOG4105C21 Displays ATPase and GTPase activities (By similarity) BGM07_010980 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BGM07_010985 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA BGM07_010990 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGM07_010995 ENOG4108IUZ ABC transporter BGM07_011000 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BGM07_011010 ENOG4105C2X Arabinose 5-phosphate isomerase BGM07_011020 ENOG4105DHJ ABC, transporter BGM07_011025 ENOG4105CY3 ABC transporter, permease BGM07_011030 ENOG4107PE3 Mammalian cell entry related domain protein BGM07_011035 ENOG4105E3I toluene tolerance BGM07_011045 ENOG4105VFK BolA family BGM07_011050 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) BGM07_011055 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase BGM07_011060 ENOG4105KME endoribonuclease L-psp BGM07_011065 ENOG4108R9M Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity) BGM07_011070 ENOG4105CXT aspartate transcarbamylase BGM07_011080 ENOG4105DBV ornithine carbamoyltransferase BGM07_011085 ENOG4105CEU Arginine dihydrolase BGM07_011105 ENOG4108MJ3 acetyltransferase BGM07_011115 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) BGM07_011120 ENOG4105MYG DNA polymerase iii, chi subunit BGM07_011125 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BGM07_011130 ENOG4108M8S permease YjgP YjgQ family protein BGM07_011135 ENOG4108K5H permease YjgP YjgQ family protein BGM07_011145 ENOG4105EXU Membrane BGM07_011150 ENOG4107JEE Short-chain dehydrogenase reductase Sdr BGM07_011160 ENOG41062JF Transcriptional regulator BGM07_011185 ENOG4105VZJ PTS System BGM07_011190 ENOG4105CK1 PTS System BGM07_011195 ENOG4105VCP PTS System BGM07_011200 ENOG4105F8D glycoside hydrolase family 4 BGM07_011205 ENOG410901P UPF0249 protein BGM07_011270 ENOG4105C26 Dehydrogenase BGM07_011300 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_011340 ENOG4106S48 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division BGM07_011345 ENOG4105KMG Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity) BGM07_011350 ENOG4105CEN a g-specific adenine glycosylase BGM07_011355 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) BGM07_011365 ENOG4105CSV Glutaminase BGM07_011370 ENOG4105CSA Coproporphyrinogen iii oxidase BGM07_011375 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BGM07_011385 ENOG4105VZ9 UPF0235 protein BGM07_011390 ENOG4108VIA integral membrane protein BGM07_011395 ENOG4105II7 pyrroline-5-carboxylate reductase BGM07_011400 ENOG4105DFA alanine racemase domain protein BGM07_011405 ENOG4105CZX twitching motility protein BGM07_011410 ENOG4105CZX twitching motility protein BGM07_011415 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) BGM07_011420 ENOG4108UJU UPF0301 protein BGM07_011425 ENOG4105D7Z glutathione synthase BGM07_011430 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BGM07_011435 ENOG4105RWS endonuclease I BGM07_011440 ENOG4105GPY SprT protein BGM07_011450 ENOG4105CPH Catalyzes the formation of S-adenosylmethionine from methionine and ATP BGM07_011460 ENOG4105CV1 Transketolase (EC 2.2.1.1) BGM07_011465 ENOG4108R4R Iron-regulated virulence regulatory protein BGM07_011470 ENOG4105D05 Receptor BGM07_011475 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BGM07_011480 ENOG4105BZA Phosphoglycerate kinase BGM07_011485 ENOG4105D2N Aldolase BGM07_011490 ENOG4105D64 Mechanosensitive ion channel BGM07_011495 ENOG4108KXH Ybak prolyl-tRNA synthetase associated BGM07_011505 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) BGM07_011510 ENOG4105MPN Membrane BGM07_011515 ENOG4108JQ1 Dehydrogenase BGM07_011520 ENOG4105E66 phosphoriboisomerase A BGM07_011525 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BGM07_011535 ENOG4107YUN Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity) BGM07_011545 ENOG4105D0A hydroxylase BGM07_011550 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BGM07_011565 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) BGM07_011570 ENOG4105Y75 tpr repeat protein BGM07_011580 ENOG4108IYU L-aspartate oxidase BGM07_011585 ENOG4105EMN RNA polymerase sigma factor BGM07_011590 ENOG41069PW sigma-e factor negative regulatory protein BGM07_011605 ENOG4105C4S Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity) BGM07_011610 ENOG4105C3F Signal peptidase i BGM07_011615 ENOG4108ZBM Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity) BGM07_011620 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) BGM07_011625 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) BGM07_011630 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) BGM07_011635 ENOG4105KJV Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity) BGM07_011640 ENOG4105BZU Histidine kinase BGM07_011650 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BGM07_011655 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BGM07_011660 ENOG4105DXN mazG family BGM07_011665 ENOG4105C8D Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity) BGM07_011670 ENOG4105C70 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity) BGM07_011675 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BGM07_011680 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) BGM07_011685 ENOG4108UH8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity) BGM07_011690 ENOG4106NZV Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity) BGM07_011695 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) BGM07_011700 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) BGM07_011715 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) BGM07_011720 ENOG4107TH8 cina domain protein BGM07_011725 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) BGM07_011730 ENOG4105Y3E Modulates RecA activity (By similarity) BGM07_011735 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BGM07_011740 ENOG4105CFH Aspartokinase BGM07_011745 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BGM07_011800 ENOG4106AFN Lyase and sodium transporter (By similarity) BGM07_011805 ENOG4107QSA Oxaloacetate decarboxylase BGM07_011810 ENOG4105D9Q decarboxylase (Beta subunit) BGM07_011820 ENOG4105W39 Membrane BGM07_011830 ENOG4105D9M gamma-glutamylcysteine synthetase BGM07_011840 ENOG4106762 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity) BGM07_011845 ENOG4108JU6 CBS domain protein BGM07_011850 ENOG4106KVJ cytochrome C assembly protein BGM07_011855 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BGM07_011860 ENOG4105K5M 30s ribosomal protein S16 BGM07_011865 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) BGM07_011870 ENOG4105D6X Specifically methylates guanosine-37 in various tRNAs (By similarity) BGM07_011875 ENOG4108YY1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity) BGM07_011880 ENOG41067SF Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) BGM07_011885 ENOG4105DHA Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity) BGM07_011890 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BGM07_011895 ENOG4105EHH Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity) BGM07_011900 ENOG4105D7Q type ii secretion system BGM07_011905 ENOG4107QHF type ii secretion system protein e BGM07_011910 ENOG4108ZUW Major pilin subunit BGM07_011915 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BGM07_011925 ENOG41073TP transcriptional regulator BGM07_011930 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BGM07_011935 ENOG4107QSN dihydrolipoamide acetyltransferase BGM07_011940 ENOG4107QN2 dihydrolipoyl dehydrogenase BGM07_011945 ENOG410630P Transcriptional regulator BGM07_011950 ENOG4108UGV hypoxanthine phosphoribosyltransferase BGM07_011955 ENOG41077A9 carbonic anhydrase BGM07_011960 ENOG4105CHH sulfate transporter BGM07_011965 ENOG4105DA5 (ABC) transporter BGM07_011970 ENOG4105E3A (ABC) transporter BGM07_011980 ENOG4105D1S lipid A biosynthesis BGM07_011985 ENOG4108IAA Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity) BGM07_011990 ENOG4105CCG Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity) BGM07_011995 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BGM07_012000 ENOG4105DJ0 Poly(A) Polymerase BGM07_012005 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) BGM07_012010 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BGM07_012015 ENOG4105PW4 Sugar fermentation stimulation protein homolog BGM07_012020 ENOG4105CQ7 ATP-dependent helicase BGM07_012025 ENOG4105BZ4 penicillin-binding protein BGM07_012030 ENOG4105D78 K07001 NTE family protein BGM07_012035 ENOG4107QIJ Aconitate hydratase 2 BGM07_012040 ENOG4105XTV UPF0231 protein BGM07_012045 ENOG4108YZA Nitrogen regulatory protein pii BGM07_012065 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BGM07_012070 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) BGM07_012080 ENOG4105E2D ec 3.2.1.52 BGM07_012085 ENOG4105RD7 BadF BadG BcrA BcrD BGM07_012095 ENOG4108JQ7 (ABC) transporter BGM07_012100 ENOG4105C3U ABC transporter BGM07_012105 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BGM07_012115 ENOG4107QRA Extracellular solute-binding protein, family 5 BGM07_012120 ENOG4105BZU Histidine kinase BGM07_012130 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) BGM07_012135 ENOG4105IPI Membrane BGM07_012140 ENOG4105CDM Glutamate-1-semialdehyde aminotransferase BGM07_012145 ENOG4108YX9 iron--sulfur cluster insertion protein erpA BGM07_012155 ENOG4105BZS acriflavin resistance protein BGM07_012160 ENOG4105DR5 peptidase BGM07_012165 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) BGM07_012175 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase BGM07_012180 ENOG4107QE9 Inherit from COG: Membrane BGM07_012185 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BGM07_012190 ENOG4105HBR Rna-binding protein BGM07_012195 ENOG4105F7M Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity) BGM07_012200 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BGM07_012205 ENOG4105EEI dihydropteroate synthase BGM07_012210 ENOG4107QJF Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity) BGM07_012235 ENOG4105K7D Required for maturation of 30S ribosomal subunits (By similarity) BGM07_012240 ENOG4105CHV Transcription elongation factor NusA BGM07_012245 ENOG4107QHU One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity) BGM07_012250 ENOG4105KG7 Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity) BGM07_012255 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) BGM07_012260 ENOG4105K77 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity) BGM07_012265 ENOG4105C62 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity) BGM07_012280 ENOG4105C3S Mate efflux family protein BGM07_012285 ENOG4106RZ4 Peptidase U32 BGM07_012290 ENOG4105CFP Peptidase U32 BGM07_012295 ENOG4105BZU Histidine kinase BGM07_012300 ENOG4105XPQ lipid carrier protein BGM07_012305 ENOG4108YYD acetyltransferase BGM07_012325 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) BGM07_012335 ENOG4105EYA deoxyribonuclease BGM07_012340 ENOG4105D9N nucleoside BGM07_012345 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BGM07_012350 ENOG4105CMW The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity) BGM07_012355 ENOG4105CZG Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity) BGM07_012360 ENOG4105D3A purine nucleoside phosphorylase DeoD-type BGM07_012370 ENOG4105EAC phosphoserine phosphatase BGM07_012380 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BGM07_012385 ENOG4105CEJ Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity) BGM07_012390 ENOG4105ETT transcriptional Regulator, LysR family BGM07_012400 ENOG4108IQE Amp-dependent synthetase and ligase BGM07_012490 ENOG41064T2 transcriptional regulator, lysR family BGM07_012495 ENOG4105E5D amino acid BGM07_012500 ENOG4105FK9 beta-D-galactosidase beta subunit BGM07_012505 ENOG4105CNT hydrolase family 2 BGM07_012510 ENOG4105CQ4 Transcriptional regulator BGM07_012515 ENOG4105CMR udp-glucose 4-epimerase BGM07_012520 ENOG4105F0Z galactose-1-phosphate uridylyltransferase BGM07_012525 ENOG4105CRD Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity) BGM07_012530 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BGM07_012545 ENOG4105DE5 Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity) BGM07_012550 ENOG41060NJ transcriptional regulator BGM07_012555 ENOG4108Y51 tRNA-binding protein BGM07_012575 ENOG4107RX3 Mg2 transporter protein cora family protein BGM07_012580 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BGM07_012585 ENOG4105E98 transcriptional regulator DeoR family BGM07_012590 ENOG4108JQ0 Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BGM07_012595 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BGM07_012605 ENOG4105CXY transporter BGM07_012610 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BGM07_012615 ENOG4105EJ3 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity) BGM07_012620 ENOG4105X2V dna damage-inducible protein BGM07_012625 ENOG4105EVZ LysR family transcriptional regulator BGM07_012635 ENOG4105E68 Sulfatase BGM07_012640 ENOG4105DSY exodeoxyribonuclease V, gamma BGM07_012650 ENOG4107QKA exodeoxyribonuclease V beta BGM07_012655 ENOG4107QYX exodeoxyribonuclease v alpha BGM07_012675 ENOG4107QZM n-acetylglutamate synthase BGM07_012690 ENOG4105CA3 membrane-bound lytic murein transglycosylase BGM07_012695 ENOG4105CUZ uba thif-type nad fad binding protein BGM07_012700 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BGM07_012705 ENOG4105BZU Histidine kinase BGM07_012710 ENOG4105C9B Cysteine desulfurase BGM07_012715 ENOG4107S0N DJ-1 family BGM07_012720 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BGM07_012750 ENOG4105K6V RNA polymerase BGM07_012765 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BGM07_012770 ENOG4105IEY (LipO)protein BGM07_012775 ENOG4105D8J Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity) BGM07_012780 ENOG4105M85 Bola protein BGM07_012790 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BGM07_012795 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BGM07_012800 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BGM07_012805 ENOG4105F5D NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BGM07_012810 ENOG4108IUB NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BGM07_012815 ENOG4105D26 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity) BGM07_012820 ENOG4105CJ2 (LipO)protein BGM07_012835 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) BGM07_012840 ENOG4105C9U ATP-dependent DNA helicase RecQ BGM07_012845 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BGM07_012860 ENOG4105C8J )-transporter BGM07_012870 ENOG4105W1I UPF0253 protein BGM07_012880 ENOG4105C90 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity) BGM07_012885 ENOG4108R96 Methyltransferase, YaeB family BGM07_012890 ENOG4105NRA 50s ribosomal protein l31 type b BGM07_012905 ENOG4105CFC Transporter BGM07_012910 ENOG4108UPT UPF0178 protein BGM07_012935 ENOG4105WP7 tRNA pseudouridine synthase C BGM07_012940 ENOG4105DR9 pseudouridine synthase BGM07_012945 ENOG4108T8E UPF0325 protein BGM07_012950 ENOG4105E1P Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity) BGM07_012955 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BGM07_012960 ENOG4105CE9 30S ribosomal protein S2 BGM07_012965 ENOG4105CU7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity) BGM07_012970 ENOG4105C41 Catalyzes the reversible phosphorylation of UMP to UDP (By similarity) BGM07_012975 ENOG4108VCV Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) BGM07_012980 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BGM07_012985 ENOG4105KNE Phosphatidate cytidylyltransferase BGM07_012990 ENOG4105CEA Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity) BGM07_012995 ENOG4105DZP Membrane-associated zinc metalloprotease BGM07_013005 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) BGM07_013010 ENOG4105D7M Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BGM07_013015 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BGM07_013020 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BGM07_013025 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BGM07_013030 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BGM07_013035 ENOG4105C0B DNA polymerase III (alpha subunit) BGM07_013040 ENOG4107QM9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity) BGM07_013045 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BGM07_013055 ENOG4108YZA Nitrogen regulatory protein pii BGM07_013060 ENOG4107NA1 Endonuclease Exonuclease phosphatase BGM07_013070 ENOG4105E9H Lytic Murein transglycosylase BGM07_013075 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) BGM07_013080 ENOG4105D1A Methyltransferase BGM07_013085 ENOG4108UMW Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) BGM07_013090 ENOG4107RZZ dna polymerase iii epsilon subunit BGM07_013105 ENOG4107QPN acyl-Coa dehydrogenase BGM07_013110 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) BGM07_013115 ENOG4105E7A Glutamine amidotransferase BGM07_013120 ENOG4108V3E phosphoribosylglycinamide formyltransferase BGM07_013125 ENOG4105CXB phosphoribosylaminoimidazole synthetase BGM07_013130 ENOG4105CZ5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity) BGM07_013135 ENOG4105C2W permease BGM07_013155 ENOG4105ERG peptidase m48, ste24p BGM07_013170 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BGM07_013175 ENOG4105RH4 Glycine cleavage system transcriptional repressor BGM07_013185 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BGM07_013200 ENOG4105C9Y Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity) BGM07_013205 ENOG4105KUZ arsenate reductase BGM07_013230 ENOG4105QZU Inner membrane protein YfeZ BGM07_013235 ENOG4105EZR dyp-type peroxidase family protein BGM07_013240 ENOG4105I03 Flagellin BGM07_013250 ENOG4105I03 Flagellin BGM07_013255 ENOG4105I03 Flagellin BGM07_013260 ENOG41063QE flagellar protein FlaG BGM07_013265 ENOG4107BRV flagellar capping protein BGM07_013275 ENOG4105MQ3 flagellar protein FliS BGM07_013280 ENOG4108JUA Transcriptional regulator BGM07_013285 ENOG4105BZU Histidine kinase BGM07_013290 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM07_013295 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BGM07_013300 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BGM07_013305 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BGM07_013315 ENOG4108JIR Flagellum-specific ATP synthase BGM07_013335 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BGM07_013340 ENOG4105DD5 Flagellar motor switch protein BGM07_013345 ENOG4105VTB flagellar biosynthesis protein fliO BGM07_013350 ENOG4105CN7 Flagellar biosynthetic protein FliP BGM07_013355 ENOG4105VS8 Flagellar biosynthetic protein fliq BGM07_013360 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BGM07_013365 ENOG4105D00 flagellar biosynthetic protein flhB BGM07_013370 ENOG4105D7B Flagellar biosynthesis protein flha BGM07_013375 ENOG4105FZW flagellar biosynthesis regulator FlhF BGM07_013380 ENOG4107R21 site-determining protein BGM07_013385 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGM07_013390 ENOG4108VYJ response regulator receiver protein BGM07_013395 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) BGM07_013400 ENOG4105CBS Chea signal transduction histidine kinase BGM07_013405 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BGM07_013410 ENOG4107QJE Chromosome Partitioning Protein BGM07_013420 ENOG4108V3W Chemotaxis protein, CheW BGM07_013430 ENOG4107EV4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity) BGM07_013435 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) BGM07_013440 ENOG41060IM Heme exporter protein BGM07_013445 ENOG4105X3C heme exporter protein BGM07_013450 ENOG4108ZKK Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity) BGM07_013455 ENOG4105DA4 cytochrome c-type biogenesis protein BGM07_013460 ENOG4107QX9 Thiol disulfide interChange protein BGM07_013465 ENOG4108M1T Cytochrome c-type biogenesis protein BGM07_013475 ENOG410903C (LipO)protein BGM07_013480 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BGM07_013485 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BGM07_013505 ENOG4105CHU acetyl-coa acetyltransferase BGM07_013510 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase BGM07_013520 ENOG4107QXK peptidase BGM07_013525 ENOG4108BY2 phosphohistidine phosphatase BGM07_013530 ENOG4108DG9 Smr protein MutS2 BGM07_013535 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) BGM07_013540 ENOG4105D10 5-enolpyruvylshikimate-3-phosphate phospholyase BGM07_013545 ENOG4105EN6 Membrane BGM07_013555 ENOG4108BPE -transporting atpase BGM07_013560 ENOG4105MH2 YfcL protein BGM07_013570 ENOG4105Q8W reductase BGM07_013575 ENOG4105CWG Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity) BGM07_013580 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BGM07_013590 ENOG4105CJ0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity) BGM07_013595 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BGM07_013605 ENOG4105DI7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity) BGM07_013610 ENOG4107QTG Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity) BGM07_013615 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BGM07_013620 ENOG4108S3P Sporulation domain protein BGM07_013625 ENOG4105E96 Colicin v production protein BGM07_013630 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BGM07_013635 ENOG4105EJC lysr family transcriptional regulator BGM07_013640 ENOG4105I93 response regulator BGM07_013650 ENOG4105WD1 Membrane BGM07_013655 ENOG4109003 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity) BGM07_013660 ENOG4107QMP dna polymerase iii subunits gamma and tau BGM07_013665 ENOG4105KDX Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity) BGM07_013670 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) BGM07_013675 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BGM07_013680 ENOG4105C44 Serine transporter BGM07_013685 ENOG4105KME endoribonuclease L-psp BGM07_013690 ENOG4105CEM UPF0597 protein BGM07_013700 ENOG4105KRS Proteinase inhibitor BGM07_013705 ENOG4105Y3U Transglycosylase-associated protein BGM07_013710 ENOG4108ZZ3 UPF0260 protein BGM07_013725 ENOG4108UYE Lactoylglutathione lyase BGM07_013735 ENOG4105G6Z alkaline phosphatase BGM07_013755 ENOG4105DHI Methyltransferase BGM07_013760 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_013765 ENOG4105DSB aldose 1-epimerase BGM07_013770 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase BGM07_013775 ENOG4105E0X reductase BGM07_013785 ENOG4105VUT cytoplasmic protein BGM07_013790 ENOG4105HDK L-asparaginase BGM07_013795 ENOG4105D07 Signal peptide peptidase, SppA BGM07_013800 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BGM07_013805 ENOG41069NU Nitroreductase BGM07_013810 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BGM07_013825 ENOG4108RU0 short-chain dehydrogenase reductase BGM07_013830 ENOG4105DGU Histone deacetylase BGM07_013840 ENOG4105E68 Sulfatase BGM07_013845 ENOG4105YDX UPF0352 protein BGM07_013850 ENOG4106V8H Nucleoid-associated protein BGM07_013865 ENOG4105DFD Na H antiporter BGM07_013870 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BGM07_013875 ENOG4105EYW Ion transport protein BGM07_013880 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BGM07_013885 ENOG4108EKI Dehydrogenase BGM07_013900 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BGM07_013905 ENOG4105M2J Glutaredoxin BGM07_013915 ENOG4105D3Y Na H antiporter BGM07_013920 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) BGM07_013925 ENOG4105EIY sodium-type flagellar protein motY BGM07_013930 ENOG4106WH9 Protein of unknown function (DUF2753) BGM07_013935 ENOG4108UYE Lactoylglutathione lyase BGM07_013940 ENOG4105CSM endonuclease III BGM07_013945 ENOG4105DZB Electron transport complex BGM07_013950 ENOG4108UQQ Electron transport complex BGM07_013955 ENOG4105D6A Electron transport complex BGM07_013965 ENOG4108R3D Electron transport complex BGM07_013970 ENOG4105DGN Electron transport complex BGM07_013985 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) BGM07_013990 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM07_014000 ENOG4105CHW UPF0052 protein BGM07_014005 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BGM07_014010 ENOG4108RIR Molybdenum cofactor biosynthesis protein BGM07_014015 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BGM07_014020 ENOG4105M00 molybdopterin converting factor, subunit 1 BGM07_014025 ENOG4108ZAF Molybdopterin BGM07_014030 ENOG4107QSI ABC, transporter BGM07_014035 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BGM07_014040 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BGM07_014045 ENOG4105C3U ABC transporter BGM07_014050 ENOG4108JQ7 (ABC) transporter BGM07_014055 ENOG4105CHF Glutathione S-transferase BGM07_014065 ENOG4107PU6 Membrane BGM07_014070 ENOG4108DNC Involved in acetate metabolism (By similarity) BGM07_014075 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) BGM07_014080 ENOG4105PQ6 UPF0208 membrane protein BGM07_014090 ENOG4105C7J ABC transporter, permease BGM07_014095 ENOG4108JJB ABC transporter BGM07_014100 ENOG4107R28 alpha amylase, catalytic region BGM07_014105 ENOG4105BZU Histidine kinase BGM07_014110 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) BGM07_014115 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BGM07_014120 ENOG410635M Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity) BGM07_014125 ENOG4105DKR Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) BGM07_014130 ENOG4105C05 Multifunctional regulator of fatty acid metabolism (By similarity) BGM07_014140 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) BGM07_014145 ENOG4105D1F ATP-binding protein BGM07_014150 ENOG4105DBI uridine monophosphokinase BGM07_014160 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BGM07_014170 ENOG4105CHH sulfate transporter BGM07_014180 ENOG4105C03 ribonuclease BGM07_014190 ENOG4105EI2 Pseudouridine synthase BGM07_014195 ENOG4108UHJ MAF-like protein BGM07_014200 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BGM07_014205 ENOG4105VGS 50s ribosomal protein l32 BGM07_014210 ENOG4105C6B Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity) BGM07_014215 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BGM07_014220 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BGM07_014225 ENOG4105CHR reductase BGM07_014230 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BGM07_014235 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BGM07_014245 ENOG4105HHA aminodeoxychorismate lyase BGM07_014250 ENOG4108ZMD Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity) BGM07_014255 ENOG4107QRG dna polymerase iii BGM07_014260 ENOG4105F8V Hydrolase, tatD family BGM07_014265 ENOG4105CI1 PTS System BGM07_014285 ENOG4105C8J )-transporter BGM07_014300 ENOG4108NRW Phospholipase, patatin family BGM07_014305 ENOG4105CA9 Pyruvate kinase BGM07_014310 ENOG4105DAG ROK family BGM07_014315 ENOG4107R88 Chemotaxis protein (CheV) BGM07_014320 ENOG4105C0B DNA polymerase III (alpha subunit) BGM07_014335 ENOG4105UBK short-chain dehydrogenase reductase BGM07_014340 ENOG4105ERU peptidase BGM07_014345 ENOG4105CAT Cytidine monophosphate kinase BGM07_014350 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BGM07_014355 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BGM07_014360 ENOG4105Q4A inner membrane protein yciS BGM07_014365 ENOG4105CFV Tetratricopeptide repeat protein BGM07_014370 ENOG4106EG9 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity) BGM07_014375 ENOG4108J59 Extracellular solute-binding protein, family 5 BGM07_014390 ENOG4105CKK Glycosyl transferase, family 2 BGM07_014400 ENOG4105SA9 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) BGM07_014410 ENOG4105DY2 Paraquat-inducible protein b BGM07_014415 ENOG4105F1S paraquat-inducible protein a BGM07_014420 ENOG4105NQN cytochrome C BGM07_014430 ENOG4105DB1 molybdopterin oxidoreductase BGM07_014435 ENOG4106WHD Tetrathionate reductase BGM07_014440 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BGM07_014445 ENOG4106AFQ Histidine kinase BGM07_014450 ENOG4108ZXC Two component transcriptional regulator, luxr family BGM07_014455 ENOG4105EXG Transcriptional regulator BGM07_014465 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) BGM07_014470 ENOG4105N6Y Thioredoxin BGM07_014485 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BGM07_014500 ENOG4105DJY efflux transporter, rnd family, mfp subunit BGM07_014510 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BGM07_014520 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BGM07_014525 ENOG4108W2Y isochorismatase BGM07_014530 ENOG41063TF transcriptional regulator (AraC BGM07_014540 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BGM07_014550 ENOG4105J12 Multidrug resistance protein mdtN BGM07_014555 ENOG4105JQN Transcriptional regulator BGM07_014575 ENOG41062D9 Histidine kinase BGM07_014580 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGM07_014585 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_014590 ENOG4105CCT upf0313 protein BGM07_014615 ENOG4105DZ2 Transcriptional regulator BGM07_014625 ENOG4105DSS Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity) BGM07_014635 ENOG4105K9H YciI-like protein BGM07_014640 ENOG4105NAU thioesterase Superfamily protein BGM07_014645 ENOG4107835 probably involved in intracellular septation (By similarity) BGM07_014655 ENOG4105BZU Histidine kinase BGM07_014665 ENOG4105CK2 sodium dicarboxylate symporter BGM07_014670 ENOG4105CEY Amp-dependent synthetase and ligase BGM07_014675 ENOG4107RYR Transcriptional regulator, Crp Fnr family BGM07_014680 ENOG4105F6H The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity) BGM07_014685 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) BGM07_014690 ENOG4105DK0 Indole-3-glycerol phosphate synthase BGM07_014695 ENOG4108I0Q anthranilate phosphoribosyltransferase BGM07_014700 ENOG4105DDQ anthranilate synthase BGM07_014705 ENOG4105CRQ synthase (Component I) BGM07_014715 ENOG4105DB7 PHP domain protein BGM07_014720 ENOG4107RTD sua5 ycio yrdc ywlc family protein BGM07_014730 ENOG4105FE9 pseudouridine synthase BGM07_014735 ENOG4108W5H UPF0263 protein BGM07_014740 ENOG4105DRH Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity) BGM07_014750 ENOG4105CQ2 DNA polymerase BGM07_014755 ENOG4105WH1 Two component transcriptional regulator luxr family BGM07_014760 ENOG4105CII The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity) BGM07_014805 ENOG4105D3D Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity) BGM07_014830 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BGM07_014835 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BGM07_014845 ENOG4108HWB Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity) BGM07_014850 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BGM07_014865 ENOG4105EAU Plays a role in nitrite reduction (By similarity) BGM07_014875 ENOG4105D3S 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BGM07_014880 ENOG4105DVI reductase, NrfD BGM07_014885 ENOG4105DA4 cytochrome c-type biogenesis protein BGM07_014890 ENOG4107QX9 Thiol disulfide interChange protein BGM07_014895 ENOG4108DMF Cytochrome C biogenesis protein BGM07_014905 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BGM07_014930 ENOG4105DIT ErfK YbiS YcfS YnhG family protein BGM07_014935 ENOG4105EAQ (twin-arginine translocation) pathway signal BGM07_014940 ENOG4105C5X domain protein BGM07_014955 ENOG4105CH5 extracellular solute-binding protein, family 7 BGM07_014965 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BGM07_014980 ENOG41067TZ transcriptional regulator, MarR family BGM07_014985 ENOG4105C94 Transporter BGM07_014990 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_015010 ENOG4105CGF Aromatic amino acid aminotransferase BGM07_015025 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BGM07_015035 ENOG4105C5S asparaginyl-tRNA synthetase BGM07_015040 ENOG4108N3W hemolysin secretion protein BGM07_015045 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BGM07_015055 ENOG4105BZU Histidine kinase BGM07_015060 ENOG4105EJQ L-serine dehydratase BGM07_015065 ENOG4105C44 Serine transporter BGM07_015070 ENOG4105P8F nudix hydrolase BGM07_015080 ENOG4105BZU Histidine kinase BGM07_015085 ENOG4105CRQ synthase (Component I) BGM07_015100 ENOG4105CM6 amino acid regulated cytosolic protein BGM07_015105 ENOG4106K28 UPF0283 membrane protein BGM07_015115 ENOG4105D9U N-acetyltransferase BGM07_015240 ENOG410829K Lysine exporter protein (Lyse ygga) BGM07_015340 ENOG4105D3W isochorismatase BGM07_015415 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BGM07_015550 ENOG4108ZI4 Glyoxalase Bleomycin resistance protein (Dioxygenase BGM07_015605 ENOG4105YGK Pfam:UPF0157 BGM07_015640 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BGM07_015685 ENOG4105CAT Cytidine monophosphate kinase BGM07_015925 ENOG4105RHY Pfam:UPF0157 BGM07_015935 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BGM07_016275 ENOG4105HHM rdd domain containing protein BGM07_016310 ENOG4108KU3 Integrase BGM07_016340 ENOG4105KWI UPF0339 protein BGM07_016395 ENOG4105Y49 secretion protein, HlyD family BGM07_016415 ENOG4105DUM transcriptional regulator, lysR family BGM07_016450 ENOG4105C8P )-transporter BGM07_016455 ENOG4105BZU Histidine kinase BGM07_016460 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM07_016465 ENOG4105BZU Histidine kinase BGM07_016470 ENOG4105CPI Metal Dependent Phosphohydrolase BGM07_016480 ENOG4105G0K glycine radical enzyme YjjI family BGM07_016485 ENOG41076CZ activating enzyme BGM07_016495 ENOG4105EE5 Membrane protein terC BGM07_016505 ENOG4105E0M Sulfatase BGM07_016510 ENOG4105DHQ Histidine kinase BGM07_016545 ENOG4105GIJ Glycine betaine BGM07_016550 ENOG4108HQS Glycine betaine BGM07_016555 ENOG4108IJ7 Glycine betaine BGM07_016570 ENOG4105C94 Transporter BGM07_016575 ENOG4108Z24 l-2,4-diaminobutyric acid acetyltransferase BGM07_016580 ENOG4108JPW Aminotransferase BGM07_016585 ENOG4108Z6K Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity) BGM07_016590 ENOG4105CZK Aspartate kinase BGM07_016595 ENOG4105CA0 peroxidase BGM07_016610 ENOG4107V40 secretion protein, HlyD family BGM07_016625 ENOG4105CEQ signal transduction histidine kinase regulating citrate malate metabolism BGM07_016630 ENOG4108V9W transcriptional regulatory protein BGM07_016635 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BGM07_016640 ENOG4108Q79 6-phosphogluconolactonase (EC 3.1.1.31) BGM07_016645 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BGM07_016670 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BGM07_016675 ENOG4105C26 Dehydrogenase BGM07_016695 ENOG4108KB1 transcriptional regulator, arac family BGM07_016725 ENOG41066XE Type III export protein BGM07_016795 ENOG4105ENX hydrolase BGM07_016800 ENOG4105ENX hydrolase BGM07_016805 ENOG4105EQ2 LysR family Transcriptional regulator BGM07_016915 ENOG4105EJ9 Membrane BGM07_016945 ENOG4105CR4 methylisocitrate lyase BGM07_016950 ENOG4105BZN citrate synthase BGM07_016955 ENOG4108I0Z Aconitate hydratase BGM07_016960 ENOG4105C7F AcnD-accessory protein PrpF BGM07_016965 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) BGM07_016970 ENOG4108R6G acetyltransferase BGM07_016985 ENOG410667J hydrolase BGM07_016990 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BGM07_016995 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) BGM07_017010 ENOG4105CDV Ompa motb domain protein BGM07_017025 ENOG4105CDV Ompa motb domain protein BGM07_017040 ENOG4105DR4 Methyltransferase BGM07_017045 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_017050 ENOG4105VSY K01512 acylphosphatase EC 3.6.1.7 BGM07_017055 ENOG4108Z0T Part of a sulfur-relay system (By similarity) BGM07_017065 ENOG4108MN8 Membrane BGM07_017070 ENOG4105CDA abc transporter atp-binding protein BGM07_017075 ENOG4105DRP amino acid AbC transporter BGM07_017080 ENOG4105EZ7 amino acid ABC transporter BGM07_017085 ENOG4107QXX ABC transporter BGM07_017100 ENOG4108VPT UPF0234 protein BGM07_017105 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BGM07_017125 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BGM07_017135 ENOG4105DY2 Paraquat-inducible protein b BGM07_017140 ENOG4105H2K paraquat-inducible protein a BGM07_017145 ENOG4105BZ1 (ABC) transporter BGM07_017150 ENOG4108ZGC gaf domain protein BGM07_017155 ENOG41073DY may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity) BGM07_017160 ENOG4105CN1 protease BGM07_017170 ENOG4105CD8 aminopeptidase N BGM07_017180 ENOG4105C7I Dehydrogenase BGM07_017185 ENOG4107QYT Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity) BGM07_017190 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) BGM07_017195 ENOG4105C4H Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity) BGM07_017205 ENOG4105C5H ABC transporter BGM07_017220 ENOG4108RKI Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity) BGM07_017225 ENOG4105DAN ATP-dependent protease BGM07_017230 ENOG4108R9Q Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity) BGM07_017415 ENOG4105BZU Histidine kinase BGM07_017430 ENOG4105EUH cytochrome C oxidase, cbb3-type, subunit i BGM07_017445 ENOG4105D6P C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity) BGM07_017455 ENOG4105C59 p-type ATPase BGM07_017470 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BGM07_017475 ENOG4105Q9Y Universal stress protein BGM07_017480 ENOG4105CB3 Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity) BGM07_017500 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BGM07_017505 ENOG4105F38 ABC transporter, permease BGM07_017510 ENOG4105D38 putrescine abc transporter BGM07_017515 ENOG4107RUE extracellular solute-binding protein family 1 BGM07_017520 ENOG4107RUE extracellular solute-binding protein family 1 BGM07_017525 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BGM07_017560 ENOG4105QAX Iron-sulfur BGM07_017565 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BGM07_017575 ENOG4109039 Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity) BGM07_017595 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) BGM07_017600 ENOG4105C5H ABC transporter BGM07_017605 ENOG4105BZU Histidine kinase BGM07_017610 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM07_017625 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BGM07_017630 ENOG4105C6R Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity) BGM07_017635 ENOG4105CVM Molybdenum cofactor synthesis domain protein BGM07_017645 ENOG4105EZX Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity) BGM07_017650 ENOG4106IUH DTW domain containing protein BGM07_017690 ENOG4107TT5 NLP P60 protein BGM07_017700 ENOG4105BZU Histidine kinase BGM07_017705 ENOG4105CMP catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity) BGM07_017710 ENOG4105FGM Fructosamine kinase BGM07_017720 ENOG4108R6K riboflavin synthase, subunit alpha BGM07_017725 ENOG4107QI1 Mate efflux family protein BGM07_017740 ENOG41082AN stage II sporulation protein BGM07_017750 ENOG4107V1M polysaccharide export protein BGM07_017765 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM07_017805 ENOG4105CPK Glycosyl transferase (Group 1 BGM07_017810 ENOG4105CND Glycosyl transferase, family 2 BGM07_017825 ENOG4105C94 Transporter BGM07_017840 ENOG4105CQ7 ATP-dependent helicase BGM07_017845 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) BGM07_017855 ENOG4108NEM leader-binding protein dmsD BGM07_017860 ENOG4107KGK dmso reductase anchor subunit BGM07_017865 ENOG4105QAX Iron-sulfur BGM07_017870 ENOG4107QY8 reductase BGM07_017900 ENOG4105BZU Histidine kinase BGM07_017910 ENOG4105CFG Acts as a chaperone (By similarity) BGM07_017915 ENOG4105CFG Acts as a chaperone (By similarity) BGM07_017940 ENOG4105BZ1 (ABC) transporter BGM07_017945 ENOG4105BZ1 (ABC) transporter BGM07_017965 ENOG4105E0U tyrosine-specific transport protein BGM07_017975 ENOG4105DHT Metal Dependent Phosphohydrolase BGM07_018005 ENOG4105BZG amino acid carrier protein BGM07_018015 ENOG410829K Lysine exporter protein (Lyse ygga) BGM07_018020 ENOG4105CTD carboxy-peptidase BGM07_018025 ENOG4105D1S lipid A biosynthesis BGM07_018030 ENOG4105E5D amino acid BGM07_018040 ENOG4105CVG Homoserine O-transsuccinylase BGM07_018045 ENOG41090FY type IV pilus biogenesis stability protein PilW BGM07_018055 ENOG4105BZU Histidine kinase BGM07_018060 ENOG4105BZU Histidine kinase BGM07_018075 ENOG4108UW5 maltose o-acetyltransferase BGM07_018095 ENOG4105MSB protein, conserved in bacteria BGM07_018100 ENOG4108ZT1 Transcriptional regulator BGM07_018115 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) BGM07_018130 ENOG4105BZU Histidine kinase BGM07_018135 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase BGM07_018140 ENOG4108JPW Aminotransferase BGM07_018145 ENOG4105C26 Dehydrogenase BGM07_018150 ENOG4105DWY Agmatine deiminase BGM07_018160 ENOG4105CJP fad dependent oxidoreductase BGM07_018165 ENOG4105C26 Dehydrogenase BGM07_018170 ENOG4107VRI Transcriptional regulator BGM07_018175 ENOG4108Z86 Glutamine amidotransferase BGM07_018185 ENOG4105CFQ glutamine synthetase BGM07_018190 ENOG4107S6Z Na H antiporter BGM07_018215 ENOG4105N14 lysine exporter protein LysE YggA BGM07_018290 ENOG4105EFX secretion protein, HlyD family BGM07_018430 ENOG4108N0N Phage Terminase Large Subunit BGM07_018440 ENOG4108ES9 ParB domain protein nuclease BGM07_018480 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BGM07_018485 ENOG4105VEQ Cold shock protein BGM07_018590 ENOG4108RXX maleylacetoacetate isomerase BGM07_018600 ENOG4105F1J Homogentisate 1,2-dioxygenase BGM07_018605 ENOG4105E6K 4-Hydroxyphenylpyruvate dioxygenase BGM07_018615 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BGM07_018635 ENOG4108QW8 Purine nucleoside phosphorylase deoD-type BGM07_018640 ENOG4107QSI ABC, transporter BGM07_018645 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BGM07_018650 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BGM07_018655 ENOG4105C3U ABC transporter BGM07_018660 ENOG4108JQ7 (ABC) transporter BGM07_018670 ENOG4107MM9 BNR Asp-box repeat-containing protein BGM07_018685 ENOG4105D38 putrescine abc transporter BGM07_018690 ENOG4105F38 ABC transporter, permease BGM07_018695 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BGM07_018700 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) BGM07_018705 ENOG4105CIF Ornithine Cyclodeaminase BGM07_018720 ENOG4105CTU Proline racemase BGM07_018750 ENOG4105EBA Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity) BGM07_018755 ENOG4108VKG metal-dependent hydrolase BGM07_018765 ENOG4107RSM transcriptional regulator BGM07_018785 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) BGM07_018790 ENOG4108IU2 vtamin B12-transporter permease BGM07_018795 ENOG4107UI5 Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity) BGM07_018820 ENOG4108UHF Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity) BGM07_018825 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) BGM07_018830 ENOG4105K4T epimerase BGM07_018835 ENOG4108ETY sodium dicarboxylate symporter BGM07_018840 ENOG4105CJB Exodeoxyribonuclease I BGM07_018845 ENOG4105VAW lrga family BGM07_018850 ENOG41067MG lrgb family BGM07_018855 ENOG4107T42 This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity) BGM07_018860 ENOG4108HH9 Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR BGM07_018865 ENOG4105FQ6 thiopurine methyltransferase BGM07_018875 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BGM07_018885 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BGM07_018890 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) BGM07_018895 ENOG4105BZU Histidine kinase BGM07_018925 ENOG4105K8R UPF0145 protein BGM07_018930 ENOG4108YZX Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity) BGM07_018935 ENOG41082NX 50s ribosomal protein l35 BGM07_018940 ENOG4108UUX IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity) BGM07_018945 ENOG4105C22 threonyL-tRNA synthetase BGM07_018960 ENOG4105CZE histidine utilization repressor BGM07_018965 ENOG4105CI2 imidazolone-5-propionate hydrolase BGM07_018970 ENOG41088SP formiminoglutamate hydrolase BGM07_018980 ENOG4105C84 Histidine ammonia-lyase BGM07_018995 ENOG4105CQB FAD linked oxidase domain protein BGM07_019010 ENOG4105CDV Ompa motb domain protein BGM07_019030 ENOG4105C8V SAICAR synthetase BGM07_019045 ENOG4105HDD phospholipase BGM07_019050 ENOG4105CQ7 ATP-dependent helicase BGM07_019055 ENOG4107R1I NAD-dependent malic enzyme BGM07_019060 ENOG4107GZ4 SanA protein BGM07_019065 ENOG4105C8P )-transporter BGM07_019070 ENOG4105BZU Histidine kinase BGM07_019090 ENOG4105C3M thioredoxin reductase BGM07_019095 ENOG4108JJ9 ABC, transporter BGM07_019100 ENOG4108JJ8 (ABC) transporter BGM07_019105 ENOG4105BZC d-serine deaminase BGM07_019110 ENOG4107QM1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) BGM07_019120 ENOG4105BZU Histidine kinase BGM07_019155 ENOG4105DWU Membrane BGM07_019165 ENOG4105DY8 decarboxylase BGM07_019170 ENOG4106KNT transcriptional regulator BGM07_019180 ENOG41090BQ Glutaredoxin BGM07_019185 ENOG4105D0C transport protein BGM07_019190 ENOG4105RKW reductase (By BGM07_019195 ENOG4107QPN acyl-Coa dehydrogenase BGM07_019200 ENOG41067SE Tetr family transcriptional regulator BGM07_019205 ENOG4105DRC Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) BGM07_019220 ENOG4108I0Y (ABC) transporter BGM07_019225 ENOG4107QI1 Mate efflux family protein BGM07_019230 ENOG4105CGD Nad-dependent epimerase dehydratase BGM07_019235 ENOG4105CUW cytochrome C-TYPE protein BGM07_019265 ENOG4105C2C drug resistance transporter, Bcr CflA BGM07_019270 ENOG4105I08 Pseudouridine synthase BGM07_019275 ENOG4105CFI type iii restriction protein res subunit BGM07_019285 ENOG4105ETX regulatoR BGM07_019290 ENOG4105EB3 Histidine kinase BGM07_019295 ENOG4105KW6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity) BGM07_019310 ENOG4105CGH 5'-nucleotidase BGM07_019320 ENOG4105XZD Fe-S protein BGM07_019330 ENOG4108ZXC Two component transcriptional regulator, luxr family BGM07_019335 ENOG4106AFQ Histidine kinase BGM07_019345 ENOG4105BZ8 glutamate synthase BGM07_019355 ENOG4108RSN SNARE associated Golgi BGM07_019360 ENOG4105VNH ABC transporter solute-binding protein BGM07_019365 ENOG4105CXZ ABC transporter, permease BGM07_019370 ENOG4108VGW abc transporter atp-binding protein BGM07_019375 ENOG4108T9J Cdp-alcohol phosphatidyltransferase BGM07_019385 ENOG4108JUA Transcriptional regulator BGM07_019390 ENOG4105EJ7 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity) BGM07_019395 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BGM07_019405 ENOG4108W1A pseudouridine synthase BGM07_019415 ENOG4105C8J )-transporter BGM07_019420 ENOG4105CQX Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity) BGM07_019425 ENOG4105C28 cystathionine BGM07_019430 ENOG4107IFA Lipase (EC 3.1.1.3) BGM07_019440 ENOG4108R3E Dna-3-methyladenine glycosylase i BGM07_019455 ENOG410624X efflux transporter, rnd family, mfp subunit BGM07_019460 ENOG4105FM1 phage shock protein C BGM07_019465 ENOG4105YYT phage shock protein B BGM07_019470 ENOG41087YS Phage shock protein A BGM07_019475 ENOG4105E51 psp operon transcriptional activator BGM07_019480 ENOG4108J59 Extracellular solute-binding protein, family 5 BGM07_019485 ENOG4108I5W peptide transport system, permease protein BGM07_019490 ENOG4108EU3 peptide transport system, permease BGM07_019495 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein BGM07_019500 ENOG4108JQ2 peptide transport system atp-binding protein BGM07_019510 ENOG4105E2M Manganese-dependent inorganic pyrophosphatase BGM07_019525 ENOG4108J2R molybdopterin oxidoreductase BGM07_019540 ENOG4105C4B ABC transporter, permease BGM07_019550 ENOG4105TMB Formate nitrite transporter BGM07_019575 ENOG4105GFG DUF218 domain BGM07_019580 ENOG4107104 thymidine kinase BGM07_019585 ENOG4105C8N cysteinyl-tRNA synthetase BGM07_019590 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BGM07_019595 ENOG4105F10 Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity) BGM07_019600 ENOG4105D58 Diguanylate phosphodiesterase BGM07_019605 ENOG4105K5B UPF0225 protein BGM07_019610 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BGM07_019615 ENOG4105C0S IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity) BGM07_019625 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BGM07_019630 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BGM07_019635 ENOG4105CIH Imidazole acetol-phosphate transaminase BGM07_019640 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BGM07_019645 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) BGM07_019650 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM07_019660 ENOG4107S6Z Na H antiporter BGM07_019665 ENOG4108YX2 DNA-binding protein BGM07_019670 ENOG4107RE1 Inosine-guanosine kinase BGM07_019680 ENOG4105CCJ Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity) BGM07_019685 ENOG41075W9 High frequency lysogenization protein HflD homolog BGM07_019690 ENOG4107QTF adenylosuccinate lyase BGM07_019715 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BGM07_019730 ENOG4107FW0 short-chain dehydrogenase reductase BGM07_019740 ENOG4105D0M Protease HtpX homolog BGM07_019750 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BGM07_019760 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BGM07_019765 ENOG4105CZF Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity) BGM07_019770 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BGM07_019775 ENOG4105KSC Transcriptional regulator, TraR DksA family BGM07_019790 ENOG4105CGR Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity) BGM07_019795 ENOG4105D1H recombination factor protein RarA BGM07_019800 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) BGM07_019805 ENOG4105CNU cell division protein FtsK BGM07_019810 ENOG4105EW9 transcriptional regulator AsnC family BGM07_019815 ENOG4105DCF alanine dehydrogenase BGM07_019825 ENOG4107R11 Transcriptional regulator BGM07_019835 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase BGM07_019870 ENOG4105BZS acriflavin resistance protein BGM07_019875 ENOG4105C1P efflux transporter, rnd family, mfp subunit BGM07_019885 ENOG4108N3W hemolysin secretion protein BGM07_019895 ENOG4108RNS Exports L-alanine (By similarity) BGM07_019900 ENOG4105BZU Histidine kinase BGM07_019910 ENOG4106032 Glutathionylspermidine synthase BGM07_019920 ENOG4105Z6B inner membrane protein yjfl BGM07_019930 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) BGM07_019935 ENOG4105UFD tol-pal system protein YbgF BGM07_019940 ENOG4105KCK Peptidoglycan-associated lipoprotein BGM07_019945 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) BGM07_019955 ENOG4105M8F Biopolymer transport protein exbD tolR BGM07_019960 ENOG4105E02 MotA TolQ exbB proton channel BGM07_019965 ENOG4107YD3 Thioesterase BGM07_019980 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BGM07_019985 ENOG4105C4M (Ubiquinol oxidase) subunit I BGM07_019990 ENOG4105CKJ The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity) BGM07_019995 ENOG4105KA4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity) BGM07_020000 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_020005 ENOG4105NHU Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity) BGM07_020010 ENOG4105C9M aspartyl-trna synthetase BGM07_020015 ENOG41081XQ Conserved Protein BGM07_020020 ENOG4105DA6 Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity) BGM07_020025 ENOG4105PFA Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity) BGM07_020035 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) BGM07_020045 ENOG4105D9I Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity) BGM07_020055 ENOG4105DUC Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity) BGM07_020060 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) BGM07_020065 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) BGM07_020070 ENOG4106371 Methyltransferase BGM07_020075 ENOG4107S90 membrAne BGM07_020080 ENOG4106WF9 DNA-binding transcriptional regulator TorR BGM07_020085 ENOG4109039 Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity) BGM07_020090 ENOG4105ETE Transcriptional regulator (LacI family BGM07_020095 ENOG4105HP8 regulator of competence-specific genes BGM07_020115 ENOG4105CXW Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity) BGM07_020120 ENOG4107QQ4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity) BGM07_020125 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BGM07_020130 ENOG4105RKX Protein of unknown function (DUF2498) BGM07_020135 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase BGM07_020145 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) BGM07_020150 ENOG4105DWA May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate BGM07_020155 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BGM07_020165 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BGM07_020170 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) BGM07_020175 ENOG4105VEQ Cold shock protein BGM07_020185 ENOG4108R99 pseudouridine synthase BGM07_020195 ENOG4105SDR Outer membrane protein OmpT BGM07_020200 ENOG4105DVT helicase BGM07_020205 ENOG4105EJ9 Membrane BGM07_020210 ENOG4108URS primosomal replication protein n'' BGM07_020215 ENOG4106428 Protein of unknown function (DUF2496) BGM07_020220 ENOG4105CGK Exodeoxyribonuclease III BGM07_020235 ENOG4105DSP amino acid AbC transporter BGM07_020240 ENOG4105E89 ABC transporter BGM07_020245 ENOG4108JEH abc transporter atp-binding protein BGM07_020260 ENOG4105C6N Formate acetyltransferase BGM07_020270 ENOG4105F1A Pyruvate formate-lyase BGM07_020280 ENOG4105XWI UPF0304 protein BGM07_020285 ENOG4105CYN Serine protein kinase BGM07_020290 ENOG4106AKX UPF0229 protein BGM07_020295 ENOG4105ED1 spovr family BGM07_020300 ENOG4105CET Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity) BGM07_020305 ENOG4105W49 UPF0434 protein BGM07_020310 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) BGM07_020315 ENOG4105BZ1 (ABC) transporter BGM07_020320 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 BGM07_020330 ENOG4105D60 lipoprotein releasing system transmembrane protein BGM07_020335 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) BGM07_020340 ENOG4105D60 lipoprotein releasing system transmembrane protein BGM07_020350 ENOG4108JA2 transcriptioN-repair coupling factor BGM07_020365 ENOG4105CEP NADH dehydrogenase BGM07_020370 ENOG4105D0Y UPF0227 protein BGM07_020395 ENOG4105K59 histidine triad (HIT) protein BGM07_020400 ENOG4108NVR Methyl-accepting chemotaxis BGM07_020410 ENOG4107SXA Phosphorylase BGM07_020420 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BGM07_020430 ENOG4105DZ0 fad dependent oxidoreductase BGM07_020435 ENOG4108Z4U Ferredoxin BGM07_020475 ENOG4105C0D helicase BGM07_020500 ENOG4107QTH restriction modification system DNA specificity domain BGM07_020550 ENOG4108KHX Diguanylate cyclase BGM07_020565 ENOG4108MNP Glycoprotein polysaccharide metabolism BGM07_020570 ENOG4105C29 acyl-CoA thioesterase BGM07_020580 ENOG4108XM1 transcriptional regulator AsnC family BGM07_020605 ENOG4105BZS acriflavin resistance protein BGM07_020610 ENOG4105ENT Efflux transporter rnd family, mfp subunit BGM07_020655 ENOG4108J8Q Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity) BGM07_020660 ENOG4105HMI Membrane BGM07_020670 ENOG4105CEY Amp-dependent synthetase and ligase BGM07_020675 ENOG4105DNI Converts SHCHC to OSB (By similarity) BGM07_020680 ENOG4108IPT Naphthoate synthase BGM07_020685 ENOG4107J5P Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity) BGM07_020690 ENOG4105C4A Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity) BGM07_020695 ENOG4105E4F Isochorismate synthase BGM07_020700 ENOG4105CHM Aminotransferase BGM07_020705 ENOG4105DK2 UPF0207 protein BGM07_020710 ENOG4105C4Q deoxyguanosinetriphosphate triphosphohydrolase-like protein BGM07_020725 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein BGM07_020730 ENOG4105EIN peptidylprolyl cis-trans isomerase BGM07_020735 ENOG4105K70 DNA-binding protein BGM07_020740 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BGM07_020745 ENOG4105CHN ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity) BGM07_020750 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) BGM07_020755 ENOG4105DEA Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation BGM07_020765 ENOG4105CQZ Histidine kinase BGM07_020780 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BGM07_020785 ENOG410835K Tripartite ATP-Independent Periplasmic transporter DctQ BGM07_020790 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BGM07_020795 ENOG4105CNG UPF0061 protein BGM07_020820 ENOG4107ZYR domain protein BGM07_020825 ENOG4105C1J atp-dependent rna helicase BGM07_020865 ENOG4105VNB Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity) BGM07_020885 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BGM07_020890 ENOG4106N3V dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83) BGM07_020895 ENOG4105C84 Histidine ammonia-lyase BGM07_020920 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BGM07_020925 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BGM07_020930 ENOG4105C2D reductase BGM07_020935 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BGM07_020950 ENOG4105CN0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity) BGM07_020955 ENOG4105D9N nucleoside BGM07_020960 ENOG4105CC0 LysR family Transcriptional regulator BGM07_020965 ENOG4105CVE Lytic murein transglycosylase BGM07_020970 ENOG4105VNG YcgL domain-containing protein BGM07_020975 ENOG4105K7U Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity) BGM07_020980 ENOG4107QMS site-determining protein BGM07_020985 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) BGM07_020990 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) BGM07_020995 ENOG4105CEY Amp-dependent synthetase and ligase BGM07_021000 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BGM07_021015 ENOG41072GX Peptidase M22 Glycoprotease BGM07_021020 ENOG4105DVT helicase BGM07_021025 ENOG4105CIY formyltetrahydrofolate deformylase BGM07_021030 ENOG4106ZCM YecM protein BGM07_021035 ENOG4105C75 arginyL-tRNA synthetase BGM07_021050 ENOG4105CE1 Ferrous iron transport protein b BGM07_021055 ENOG4105XFK Ferrous iron transport protein A BGM07_021065 ENOG4107S4Z Activates expression of the rhaBAD and rhaT operons (By similarity) BGM07_021070 ENOG4105NXV High-affinity zinc uptake system protein BGM07_021075 ENOG4105FDK ABC transporter BGM07_021080 ENOG4105FAV ABC, transporter BGM07_021085 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BGM07_021090 ENOG4105CMV Succinyl-CoA synthetase subunit beta BGM07_021095 ENOG4105C7S Dehydrogenase BGM07_021100 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BGM07_021105 ENOG4105E33 succinate dehydrogenase BGM07_021110 ENOG4105C00 Succinate dehydrogenase (Flavoprotein subunit) BGM07_021115 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein BGM07_021120 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit BGM07_021125 ENOG4105BZN citrate synthase BGM07_021130 ENOG4107QNR UPF0135 protein BGM07_021140 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 BGM07_021145 ENOG4107CDU Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity) BGM07_021150 ENOG4105EV9 Alpha Beta Hydrolase BGM07_021160 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) BGM07_021170 ENOG41090R7 Ferric uptake BGM07_021175 ENOG4105CX6 glutaminyL-tRNA synthetase BGM07_021180 ENOG4105CI1 PTS System BGM07_021190 ENOG4105CE4 GlcNAc 6-P deacetylase BGM07_021195 ENOG4105E2R ROK family BGM07_021200 ENOG4105CKD glutathione-regulated potassium-efflux system protein BGM07_021205 ENOG4105CAQ asparagine synthetase BGM07_021210 ENOG4105MDZ Transcriptional activator rfaH BGM07_021215 ENOG4105DUX Transporter BGM07_021220 ENOG4105CFX Catalyzes the ferrous insertion into protoporphyrin IX (By similarity) BGM07_021225 ENOG4105CC8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity) BGM07_021230 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) BGM07_021235 ENOG4108DQ1 activator toxR BGM07_021255 ENOG4108RE9 Phosphodiesterase BGM07_021285 ENOG4105ECP epimerase BGM07_021290 ENOG4105E1F short-chain dehydrogenase reductase BGM07_021295 ENOG4107QR8 Thioredoxin BGM07_021300 ENOG4105EJG cellulose synthase BGM07_021305 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BGM07_021310 ENOG4107EEX Cellulose synthase regulator protein BGM07_021315 ENOG4107QZ7 Cellulose synthase catalytic subunit BGM07_021330 ENOG4105U74 cellulose biosynthesis protein BcsE BGM07_021335 ENOG4105D1V cellulose synthase operon protein YhjU BGM07_021340 ENOG4107QX8 SPFH domain, Band 7 family protein BGM07_021355 ENOG4105C77 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity) BGM07_021360 ENOG4107NPY receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity) BGM07_021365 ENOG4105EXN Sulfate transport protein CysZ BGM07_021370 ENOG4105C6T cysteine synthase BGM07_021380 ENOG4105KZ7 phosphocarrier protein hpr BGM07_021385 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BGM07_021390 ENOG4105C5Y PTS System BGM07_021400 ENOG4105I03 Flagellin BGM07_021410 ENOG4105I03 Flagellin BGM07_021415 ENOG4105DTJ flagellar hook-associated protein BGM07_021425 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BGM07_021430 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BGM07_021435 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BGM07_021440 ENOG4105CGA flagellar basal-body rod protein FlgG BGM07_021445 ENOG4108KPB Flagellar basal-body rod protein FlgF BGM07_021455 ENOG4105BZE flagellar hook protein, FlgE BGM07_021460 ENOG4105W00 Flagellar hook capping protein BGM07_021465 ENOG4108ZC9 flagellar basal-body rod protein flgc BGM07_021470 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BGM07_021475 ENOG4105BZU Histidine kinase BGM07_021480 ENOG4107R88 Chemotaxis protein (CheV) BGM07_021525 ENOG4105UYK outer membrane protein a BGM07_021530 ENOG4105C20 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity) BGM07_021540 ENOG41081QG Porin Gram-negative type BGM07_021550 ENOG4105C59 p-type ATPase BGM07_021565 ENOG4105E2D ec 3.2.1.52 BGM07_021585 ENOG4108DG9 Smr protein MutS2 BGM07_021590 ENOG4105FE9 pseudouridine synthase BGM07_021595 ENOG4108Z66 YbaK ebsC protein BGM07_021600 ENOG4105CGH 5'-nucleotidase BGM07_021605 ENOG4105CXR Phospho-2-dehydro-3-deoxyoctonate aldolase BGM07_021610 ENOG41063JG Transcriptional regulator BGM07_021615 ENOG4108YY7 Invasion gene expression up-regulator SirB BGM07_021620 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BGM07_021625 ENOG4105C8K Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity) BGM07_021630 ENOG4105C7E Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity) BGM07_021635 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) BGM07_021640 ENOG4105CTR Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity) BGM07_021645 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BGM07_021650 ENOG4108ZPD The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity) BGM07_021655 ENOG4105C3G gtp-binding protein BGM07_021770 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BGM07_021775 ENOG4105CIW Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity) BGM07_021780 ENOG4105C9A Phoh family BGM07_021785 ENOG4105KGE Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity) BGM07_021790 ENOG4108JU5 Magnesium and cobalt efflux protein BGM07_021795 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BGM07_021800 ENOG4107PAI alpha helical protein BGM07_021805 ENOG4105C8T Leucyl-tRNA synthetase BGM07_021810 ENOG4108U2H Rare lipoprotein B BGM07_021815 ENOG4105DJF DNA polymerase III, delta' subunit BGM07_021820 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) BGM07_021825 ENOG4108UXA Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity) BGM07_021830 ENOG4105CJN penicillin-binding protein BGM07_021835 ENOG4105CNI cell division protein FtsW BGM07_021840 ENOG4105K6T rare lipoprotein A BGM07_021845 ENOG4105DZ1 carboxypeptidase BGM07_021850 ENOG4108Z43 UPF0250 protein BGM07_021855 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) BGM07_021860 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) BGM07_021865 ENOG4105C65 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity) BGM07_021870 ENOG4108JYZ YitT family BGM07_021885 ENOG4105CG3 alpha amylase, catalytic region BGM07_021890 ENOG4105C5Y PTS System BGM07_021895 ENOG4105D4X repressor BGM07_021900 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BGM07_021910 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BGM07_021915 ENOG4108UMI ABC transporter, permease BGM07_021920 ENOG4105D01 (LipO)protein BGM07_021925 ENOG4105EXF Zn-ribbon-containing, possibly nucleic-acid-binding protein BGM07_021930 ENOG4108T6E Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity) BGM07_021935 ENOG4107R1K Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity) BGM07_021945 ENOG4105BZU Histidine kinase BGM07_021950 ENOG4105EWT decarboxylase family BGM07_021955 ENOG4105CIQ May have a role in processing of nucleic acids. It is probably not an exonuclease BGM07_021965 ENOG4105EZ6 Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity) BGM07_021970 ENOG4105M08 Membrane BGM07_021980 ENOG4105ETT transcriptional Regulator, LysR family BGM07_021985 ENOG4105D8I Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity) BGM07_021990 ENOG4107QKZ Ompa motb domain protein BGM07_021995 ENOG4105E14 MotA TolQ exbB proton channel BGM07_022000 ENOG41067QG Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BGM07_022005 ENOG4105CTB Polyprenyl synthetase BGM07_022010 ENOG4105C2V Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity) BGM07_022015 ENOG4108ZAI phosphatidylglycerophosphatase a BGM07_022020 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BGM07_022025 ENOG4107YIM Involved in the transcription termination process (By similarity) BGM07_022030 ENOG4108UTT Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity) BGM07_022045 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BGM07_022050 ENOG4108Z11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity) BGM07_022055 ENOG4105C2S Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity) BGM07_022060 ENOG4105CGT Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity) BGM07_022065 ENOG4108UVK Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity) BGM07_022070 ENOG4108DJV Fermentation respiration switch protein BGM07_022075 ENOG4105DYA Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity) BGM07_022080 ENOG4105C7N Xanthine uracil vitamin C permease BGM07_022085 ENOG4105CIN aminoacyl-histidine dipeptidase BGM07_022110 ENOG4108ETH Formylglycinamide ribotide synthetase BGM07_022115 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) BGM07_022125 ENOG4108Z6B deaminase BGM07_022130 ENOG4105CFC Transporter BGM07_022165 ENOG4105BZ5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity) BGM07_022170 ENOG4105CFG Acts as a chaperone (By similarity) BGM07_022180 ENOG4105K90 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ BGM07_022185 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BGM07_022195 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BGM07_022200 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BGM07_022205 ENOG4105VDB UPF0125 protein BGM07_022210 ENOG4108Z1B Cyclase dehydrase BGM07_022215 ENOG4108UH4 Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity) BGM07_022225 ENOG4105DFP Integrase BGM07_022275 ENOG4105ETT transcriptional Regulator, LysR family BGM07_022280 ENOG4105DGM nitrilase cyanide hydratase and apolipoprotein n-acyltransferase BGM07_022300 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) BGM07_022305 ENOG4108IQK o-acetylhomoserine BGM07_022335 ENOG4105MWK D-amino acid dehydrogenase, small subunit BGM07_022340 ENOG4105BZG amino acid carrier protein BGM07_022350 ENOG4106HK8 GPR1 FUN34 yaaH family protein BGM07_022360 ENOG4107S6Z Na H antiporter BGM07_022365 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) BGM07_022370 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BGM07_022375 ENOG4105DVS Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) BGM07_022390 ENOG4105DKZ GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity) BGM07_022395 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BGM07_022400 ENOG4105N21 Membrane BGM07_022405 ENOG4105CUT histidyl-tRNA synthetase BGM07_022410 ENOG4105C4E Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity) BGM07_022420 ENOG4105C55 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs BGM07_022425 ENOG4108UGX Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity) BGM07_022430 ENOG4105BZ6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity) BGM07_022435 ENOG4105WVQ Fe-S assembly protein IscX BGM07_022440 ENOG4108ZIT Ferredoxin, 2FE-2S BGM07_022445 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB BGM07_022450 ENOG4108SWN Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity) BGM07_022455 ENOG4108Z4V iron-sulfur cluster assembly BGM07_022460 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BGM07_022465 ENOG4105C3J Cysteine desulfurase BGM07_022470 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family BGM07_022475 ENOG4105CVS RNA methyltransferase TrmH family, group 1 BGM07_022480 ENOG4105ECY inositol monophosphatase BGM07_022485 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BGM07_022490 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BGM07_022495 ENOG4105VIE preprotein translocase, subunit YajC BGM07_022500 ENOG4105C6U Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity) BGM07_022505 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BGM07_022520 ENOG4105W87 Cbs domain BGM07_022525 ENOG4108I9X Isocitrate lyase BGM07_022530 ENOG4107QP3 malate synthase g BGM07_022535 ENOG4105C5Q Transcriptional regulator BGM07_022540 ENOG4105D3R alkyl hydroperoxide reductase BGM07_022550 ENOG4106N3A copper homeostasis protein cutc BGM07_022555 ENOG4105CSR polyphosphate kinase 2 BGM07_022565 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) BGM07_022570 ENOG4105E2Z phosphate ABC transporter (Permease BGM07_022575 ENOG4105C8U phosphate abc transporter BGM07_022580 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BGM07_022585 ENOG4105C9X ppx gppa phosphatase BGM07_022595 ENOG4105BZU Histidine kinase BGM07_022600 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BGM07_022610 ENOG4105DH7 May be involved in recombination (By similarity) BGM07_022615 ENOG4105CFP Peptidase U32 BGM07_022620 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BGM07_022680 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BGM07_022685 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BGM07_022690 ENOG4105C34 Pseudouridine synthase BGM07_022695 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BGM07_022700 ENOG4105CHQ Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity) BGM07_022705 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA BGM07_022715 ENOG4108K16 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BGM07_022720 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) BGM07_022725 ENOG4107SC1 transglycosylase BGM07_022730 ENOG4105C5H ABC transporter BGM07_022745 ENOG4105DR5 peptidase BGM07_022750 ENOG4105EHE chorismate mutase- prephenate dehydrogenase BGM07_022755 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BGM07_022760 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) BGM07_022765 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) BGM07_022770 ENOG4105E15 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate BGM07_022790 ENOG4108HRK Histidine kinase BGM07_022795 ENOG4108NEV two component transcriptional regulator, LytTR family BGM07_022800 ENOG4105C48 Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity) BGM07_022805 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BGM07_022810 ENOG4105M02 This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity) BGM07_022815 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) BGM07_022820 ENOG4105DTN riboflavin biosynthesis protein ribF BGM07_022825 ENOG4105CJR Integral membrane protein (MviN BGM07_022830 ENOG4105KQV Binds directly to 16S ribosomal RNA (By similarity) BGM07_022840 ENOG41080HT Transcriptional regulator, arsr family BGM07_022845 ENOG41063Z6 transcriptional regulator, lysR family BGM07_022860 ENOG4105C0V Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity) BGM07_022865 ENOG4105C3B Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity) BGM07_022870 ENOG4105HF0 Membrane BGM07_022875 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase BGM07_022880 ENOG4105EJF Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity) BGM07_022890 ENOG4105IRT Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity) BGM07_022900 ENOG4105CPC Aldo Keto reductase BGM07_022910 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM07_022915 ENOG4105CRK lysyL-tRNA synthetase BGM07_022920 ENOG4105CG1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity) BGM07_022925 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BGM07_022930 ENOG4105T95 Thiol disulfide interChange protein BGM07_022935 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BGM07_022940 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) BGM07_022945 ENOG4105CWM branched-chain amino acid transport system II carrier protein BGM07_022950 ENOG4107S47 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity) BGM07_022955 ENOG4105C1J atp-dependent rna helicase BGM07_022960 ENOG4105D1Q UPF0246 protein BGM07_022965 ENOG4105BZG amino acid carrier protein BGM07_022980 ENOG4105D5S Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity) BGM07_022990 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) BGM07_022995 ENOG4108VKA Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity) BGM07_023000 ENOG4105D98 threonine synthase BGM07_023005 ENOG4105D5I Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity) BGM07_023025 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) BGM07_023040 ENOG41065U4 response regulator BGM07_023050 ENOG4105BZU Histidine kinase BGM07_023060 ENOG4105N5T Radical SAM Protein BGM07_023075 ENOG4105CBC glutamate synthase BGM07_023080 ENOG4105BZ8 glutamate synthase BGM07_023090 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) BGM07_023095 ENOG4105DH2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity) BGM07_023100 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BGM07_023105 ENOG4105EN6 Membrane BGM07_023110 ENOG4105VP0 transcriptional regulator, lysR family BGM07_023115 ENOG4105EJ9 Membrane BGM07_023130 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BGM07_023135 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BGM07_023140 ENOG4105DUK Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity) BGM07_023145 ENOG4105M6F mutator MutT protein BGM07_023150 ENOG4105CI6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving BGM07_023160 ENOG4105C7C involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BGM07_023165 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BGM07_023170 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BGM07_023175 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BGM07_023180 ENOG4105DFU Cell wall formation (By similarity) BGM07_023185 ENOG4105DVQ Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity) BGM07_023195 ENOG4105DMZ Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity) BGM07_023200 ENOG4105CPY First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity) BGM07_023205 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BGM07_023210 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BGM07_023215 ENOG4105CJN penicillin-binding protein BGM07_023220 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BGM07_023225 ENOG4105CGJ Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity) BGM07_023240 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BGM07_023250 ENOG41082RQ UPF0102 protein BGM07_023255 ENOG4105F55 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity) BGM07_023260 ENOG4105W4M Transport-associated protein BGM07_023265 ENOG4105KB2 stringent starvation protein b BGM07_023270 ENOG4107MKT Stringent starvation protein a BGM07_023275 ENOG4105EIX cytochrome c1 BGM07_023280 ENOG4105DJ5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BGM07_023285 ENOG4108R5F Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity) BGM07_023290 ENOG4108UJD 30S ribosomal protein S9 BGM07_023295 ENOG4108UM5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity) BGM07_023305 ENOG4105D6Z AFG1 family ATPase BGM07_023310 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III BGM07_023315 ENOG4105C0H protease BGM07_023320 ENOG4105C0H protease BGM07_023325 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BGM07_023330 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BGM07_023335 ENOG4105IPS esterase BGM07_023340 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BGM07_023345 ENOG4108SX3 cytoplasmic protein BGM07_023350 ENOG41087AY ADP-Ribose pyrophosphatase BGM07_023355 ENOG4105DFG type I secretion outer membrane protein BGM07_023360 ENOG4105DW0 Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity) BGM07_023365 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) BGM07_023370 ENOG4108NVR Methyl-accepting chemotaxis BGM07_023380 ENOG4105I7R Adenylate cyclase BGM07_023385 ENOG4107IX6 phosphate transport regulator BGM07_023390 ENOG4105CJ3 phosphate transporter BGM07_023395 ENOG4106MWK domain protein BGM07_023410 ENOG4105D4J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate BGM07_023415 ENOG4105DWR Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity) BGM07_023420 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BGM07_023425 ENOG4107ZVW dihydroneopterin aldolase BGM07_023430 ENOG4105K7Z Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity) BGM07_023435 ENOG4108WC5 Alpha Beta Hydrolase Fold protein BGM07_023440 ENOG4105CPM Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BGM07_023445 ENOG4105VCC 30S ribosomal protein S21 BGM07_023450 ENOG4105KTH gatB Yqey BGM07_023455 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BGM07_023460 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BGM07_023550 ENOG4105KCV RNA signal recognition particle 4.5S RNA BGM07_023570 ENOG4105D01 (LipO)protein BGM07_023605 ENOG4105CTS PTS system mannitol-specific BGM07_023610 ENOG4107SQ3 mannitol-1-phosphate 5-dehydrogenase BGM07_023615 ENOG4105E61 Mannitol repressor protein BGM07_023620 ENOG4105MN5 HAD-superfamily hydrolase subfamily IA variant 3 BGM07_023625 ENOG4105GR3 Histidine kinase BGM07_023640 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BGM07_023645 ENOG410804X Transcriptional regulator BGM07_023650 ENOG4105CA9 Pyruvate kinase BGM07_023660 ENOG4105BZU Histidine kinase BGM07_023665 ENOG4108ZP8 Acetolactate synthase small subunit BGM07_023670 ENOG4105C7K acetolactate synthase BGM07_023675 ENOG4108IQE Amp-dependent synthetase and ligase BGM07_023680 ENOG41064T2 transcriptional regulator, lysR family BGM07_023700 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) BGM07_023705 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BGM07_023710 ENOG4105CQI Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BGM07_023715 ENOG4105MQS Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity) BGM07_023725 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) BGM07_023730 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) BGM07_023735 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BGM07_023740 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) BGM07_023745 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) BGM07_023750 ENOG4105NWN ApaG protein BGM07_023755 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) BGM07_023760 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BGM07_023770 ENOG4105DWK Membrane BGM07_023775 ENOG4105C9R An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control BGM07_023780 ENOG4105K46 50S ribosomal protein l27 BGM07_023785 ENOG4105KK9 This protein binds to 23S rRNA in the presence of protein L20 (By similarity) BGM07_023790 ENOG4105EAH synthase BGM07_023800 ENOG4105C80 Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity) BGM07_023805 ENOG410682Y Regulates arginine biosynthesis genes (By similarity) BGM07_023835 ENOG4107T0D ABC, transporter BGM07_023840 ENOG4106SMU thiamine transporter membrane protein BGM07_023845 ENOG4105DP9 ABC transporter BGM07_023850 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BGM07_023855 ENOG4105DFU Cell wall formation (By similarity) BGM07_023860 ENOG4105CZI D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 BGM07_023865 ENOG4105F0N pyrophosphate phospho-hydrolase BGM07_023875 ENOG41066HZ AIG2-like family BGM07_023885 ENOG4105CFU surface antigen BGM07_023890 ENOG4108HW8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity) BGM07_023895 ENOG41061GZ Protein of unknown function (DUF1107) BGM07_023900 ENOG4108UUE Transcriptional regulator BGM07_023915 ENOG4108I0Y (ABC) transporter BGM07_023935 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BGM07_023945 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) BGM07_023950 ENOG4105C11 sulfate adenylyltransferase), subunit 2 BGM07_023955 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) BGM07_023960 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic BGM07_023970 ENOG4105C1J atp-dependent rna helicase BGM07_023975 ENOG4107YB6 acetyltransferase, (GNAT) family BGM07_023985 ENOG4108V1T peptidylprolyl cis-trans isomerase BGM07_023995 ENOG4108ZT0 50S ribosomal protein l17 BGM07_024000 ENOG4105CTF DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity) BGM07_024005 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BGM07_024010 ENOG4108UHH Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity) BGM07_024015 ENOG4108Z04 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits BGM07_024025 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BGM07_024030 ENOG4108UZ0 Binds to the 23S rRNA (By similarity) BGM07_024035 ENOG4105VPB 50S ribosomal protein L30 BGM07_024040 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BGM07_024050 ENOG4108R5J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity) BGM07_024055 ENOG4108UJY One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity) BGM07_024060 ENOG4105VBI Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity) BGM07_024065 ENOG4105CW6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits BGM07_024070 ENOG4105KAR One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity) BGM07_024075 ENOG4108UNN Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity) BGM07_024080 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BGM07_024085 ENOG41083MP 50s ribosomal protein l29 BGM07_024090 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BGM07_024095 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BGM07_024100 ENOG4105KAP The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity) BGM07_024105 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BGM07_024110 ENOG4105CFD One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity BGM07_024115 ENOG41080KG One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity) BGM07_024120 ENOG4106U5A One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) BGM07_024125 ENOG4105EEE One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity) BGM07_024130 ENOG4108Z10 Involved in the binding of tRNA to the ribosomes (By similarity) BGM07_024135 ENOG4105VFB Binds the 23S rRNA (By similarity) BGM07_024140 ENOG4105C25 Primosomal protein n' BGM07_024145 ENOG4105ETE Transcriptional regulator (LacI family BGM07_024155 ENOG4108R5P Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity) BGM07_024160 ENOG4105C4N this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity) BGM07_024165 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BGM07_024170 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) BGM07_024175 ENOG41065UX Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity) BGM07_024180 ENOG4105CBT Fructose-1,6-bisphosphatase BGM07_024205 ENOG4105CP7 Triose-phosphate isomerase BGM07_024225 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BGM07_024235 ENOG4105D3Q Sugar transferase BGM07_024250 ENOG4107TYR Glycosyl Transferase BGM07_024270 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BGM07_024275 ENOG4108IJ1 Dehydrogenase BGM07_024280 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BGM07_024285 ENOG4105CY0 Metallo-Beta-Lactamase BGM07_024295 ENOG4107V1M polysaccharide export protein BGM07_024310 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BGM07_024315 ENOG4108IJ1 Dehydrogenase BGM07_024320 ENOG4108TJN glycosyl transferase group 1 BGM07_024345 ENOG4105ESV Glycosyl transferase, family 4 BGM07_024355 ENOG4108MDC (LipO)protein BGM07_024365 ENOG4105E3R (LipO)protein BGM07_024370 ENOG4105CUI Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity) BGM07_024375 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase BGM07_024380 ENOG4105XA0 heptosyltransferase ii BGM07_024385 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BGM07_024390 ENOG41066S7 Glycosyltransferase family 52 BGM07_024395 ENOG4105F0R Cytidylyltransferase BGM07_024410 ENOG4105D2T synthase BGM07_024415 ENOG4107SE4 UDP-N-acetylglucosamine 2-epimerase BGM07_024420 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BGM07_024435 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BGM07_024440 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BGM07_024445 ENOG4105CHR reductase BGM07_024465 ENOG4108P1X synthase BGM07_024480 ENOG4105C1B dTDP-glucose 4-6-dehydratase BGM07_024485 ENOG4108W7E Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity) BGM07_024490 ENOG41080IJ Diacylglycerol kinase BGM07_024495 ENOG4105DKP glycosyl transferase, family 9 BGM07_024500 ENOG4106WTF Glycosyl transferase, family 2 BGM07_024510 ENOG4108ZEF Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity) BGM07_024515 ENOG4108JMC lipopolysaccharide core biosynthesis protein BGM07_024525 ENOG4105ERD Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity) BGM07_024540 ENOG4105KDC 50s ribosomal protein l28 BGM07_024545 ENOG4105W5Q DNA repair protein (RadC BGM07_024550 ENOG4105C8Q Methyl-accepting chemotaxis BGM07_024560 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BGM07_024565 ENOG4105EC0 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity) BGM07_024570 ENOG4105D1S lipid A biosynthesis BGM07_024575 ENOG4107QP2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity) BGM07_024580 ENOG4105ED0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity) BGM07_024585 ENOG4105DSJ YicC domain protein BGM07_024595 ENOG4108JQ7 (ABC) transporter BGM07_024605 ENOG4107QRA Extracellular solute-binding protein, family 5 BGM07_024610 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BGM07_024615 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BGM07_024645 ENOG4109015 Biopolymer transport protein exbD tolR BGM07_024660 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) BGM07_024665 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) BGM07_024670 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BGM07_024675 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase BGM07_024680 ENOG4105CB5 ATP-dependent DNA helicase recG BGM07_024690 ENOG4105C2W permease BGM07_024695 ENOG4105E0F Histidine kinase BGM07_024700 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BGM07_024710 ENOG4108RRZ Transcription elongation factor GreB BGM07_024720 ENOG4105BZM domain protein BGM07_024730 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) BGM07_024735 ENOG4105MJ2 Competence protein BGM07_024740 ENOG4107RUK Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity) BGM07_024745 ENOG4107RK2 ADP-ribose diphosphatase NudE BGM07_024755 ENOG4105PIC general secretion pathway protein N BGM07_024760 ENOG4105U1E general secretion pathway protein M BGM07_024765 ENOG4108BY5 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity) BGM07_024770 ENOG4108RTD type II secretion system protein K BGM07_024775 ENOG4108WWZ General secretion pathway protein J BGM07_024780 ENOG4105X5Z General secretion pathway protein I BGM07_024785 ENOG4105VWV general secretion pathway protein h BGM07_024790 ENOG4108VAU general secretion pathway protein G BGM07_024795 ENOG4105D7Q type ii secretion system BGM07_024800 ENOG4107QHF type ii secretion system protein e BGM07_024810 ENOG4108XKW General secretion pathway protein C BGM07_024815 ENOG4105VEJ Heat shock protein BGM07_024820 ENOG4105F4C Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity) BGM07_024825 ENOG4105DJ1 Phosphoenolpyruvate Carboxylase BGM07_024835 ENOG4105SUU thioesterase domain BGM07_024840 ENOG4108YYA Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity) BGM07_024845 ENOG4107S2Z UPF0761 membrane protein BGM07_024870 ENOG4105C5F glutamine synthetase BGM07_024880 ENOG4105CUX Signal transduction histidine kinase BGM07_024885 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BGM07_024890 ENOG4105BZU Histidine kinase BGM07_024895 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) BGM07_024900 ENOG4105D4P Coproporphyrinogen iii oxidase BGM07_024905 ENOG4105XCT Protein of unknown function (DUF2489) BGM07_024910 ENOG4105ZR3 A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity) BGM07_024930 ENOG4106RE7 Cytochrome BGM07_024935 ENOG4105WHM Necessary for normal cell division and for the maintenance of normal septation (By similarity) BGM07_024945 ENOG4105C2M dna polymerase I BGM07_024960 ENOG4105D52 delta-aminolevulinic acid dehydratase BGM07_024970 ENOG4105F8V Hydrolase, tatD family BGM07_024980 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BGM07_024985 ENOG4105X8U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity) BGM07_024990 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BGM07_024995 ENOG4105CNK Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity) BGM07_025000 ENOG4105JC1 sterol-binding domain protein BGM07_025005 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) BGM07_025010 ENOG4105CGY Dna recombination protein BGM07_025020 ENOG4105BZU Histidine kinase BGM07_025025 ENOG4105DSF transport protein BGM07_025055 ENOG4107TE5 Lipid kinase BGM07_025075 ENOG4105K3G Periplasmic Protein BGM07_025080 ENOG4108JUA Transcriptional regulator BGM07_025085 ENOG4105CBX hi0933 family BGM07_025090 ENOG4108V6B universal stress protein B BGM07_025095 ENOG41090A1 ferritin BGM07_025100 ENOG4108M6U Universal stress protein A BGM07_025105 ENOG4105EMK carboxylate amino acid amine transporter BGM07_025115 ENOG4105FFN Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity) BGM07_025120 ENOG4105BZU Histidine kinase BGM07_025125 ENOG4108VVK transcriptional Regulator, AsnC BGM07_025130 ENOG4105DGW oligopeptidase A BGM07_025135 ENOG4105D6S protein involved in catabolism of external DNA BGM07_025140 ENOG4105DC8 reductase BGM07_025145 ENOG4107RSM transcriptional regulator BGM07_025150 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BGM07_025155 ENOG4108UHU Aldolase BGM07_025160 ENOG4105C6Z Gluconate BGM07_025165 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BGM07_025170 ENOG4105C01 Dihydroxy-acid dehydratase BGM07_025175 ENOG4108ZBZ Catalyzes the excretion of spermidine (By similarity) BGM07_025180 ENOG41090TI Catalyzes the excretion of spermidine (By similarity) BGM07_025185 ENOG41064T2 transcriptional regulator, lysR family BGM07_025190 ENOG4105DIQ Transcriptional regulator BGM07_025195 ENOG4105D9P serine threonine protein kinase BGM07_025225 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BGM07_025230 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BGM07_025235 ENOG4105DEF Extracellular solute-binding protein, family 5 BGM07_025240 ENOG4108JQ6 ABC transporter BGM07_025290 ENOG4105MPD Cytochrome BGM07_025295 ENOG4105C4R Atp-dependent dna helicase BGM07_025300 ENOG41067SE Tetr family transcriptional regulator BGM07_025305 ENOG410624X efflux transporter, rnd family, mfp subunit BGM07_025310 ENOG4105BZS acriflavin resistance protein BGM07_025320 ENOG4105W0Z cytoplasmic protein BGM07_025325 ENOG4105C6M Alpha-keto-beta-hydroxylacyl reductoisomerase BGM07_025330 ENOG4105EMY transcriptional regulator BGM07_025375 ENOG4108Z0R Transferase BGM07_025380 ENOG4105SG3 Protein of unknown function (DUF1488) BGM07_025385 ENOG4105E2X shikimate dehydrogenase BGM07_025390 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) BGM07_025395 ENOG4105EK0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity) BGM07_025400 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BGM07_025405 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BGM07_025410 ENOG4108WI1 Dna topoisomerase BGM07_025415 ENOG4108RPN Protein smg homolog BGM07_025420 ENOG4105C79 DNA protecting protein DprA BGM07_025430 ENOG4108Z02 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) BGM07_025435 ENOG4105CAE Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity) BGM07_025440 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B BGM07_025445 ENOG4105C1A potassium transporter peripheral membrane BGM07_025450 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) BGM07_025460 ENOG4108UT2 hemolysin iii BGM07_025465 ENOG4108N23 SpoOM-related protein BGM07_025475 ENOG4105PC1 Conserved Protein BGM07_025485 ENOG4105E27 serine threonine protein kinase BGM07_025490 ENOG4108Z33 Thiol disulfide Interchange Protein BGM07_025495 ENOG4106HNH Acyl-transferase BGM07_025505 ENOG4105C0P Mg chelatase subunit ChlI BGM07_025515 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit BGM07_025520 ENOG4105CM2 brancheD-chain amino acid aminotransferase BGM07_025525 ENOG4105C01 Dihydroxy-acid dehydratase BGM07_025530 ENOG4105C7B Threonine dehydratase BGM07_025535 ENOG4105F52 Transcriptional regulator BGM07_025540 ENOG4105CZQ inner membrane transport protein YdhC BGM07_025550 ENOG4105EAD ABC transporter BGM07_025555 ENOG4105CAJ Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity) BGM07_025560 ENOG4105KNM Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity) BGM07_025565 ENOG4105C4J Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity) BGM07_025570 ENOG4105J80 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity) BGM07_025575 ENOG4105CDG Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity) BGM07_025580 ENOG4107S15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BGM07_025585 ENOG4107Z6K F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BGM07_025590 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BGM07_025595 ENOG4105EE4 it plays a direct role in the translocation of protons across the membrane (By similarity) BGM07_025600 ENOG410684E atp synthase BGM07_025605 ENOG4105FA0 parb-like partition protein BGM07_025610 ENOG4107QJE Chromosome Partitioning Protein BGM07_025615 ENOG4105D28 Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity) BGM07_025620 ENOG4107RE5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)