locus-tag	class	description
C7Y67_00045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7Y67_00055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7Y67_00110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7Y67_00130	COG4974	Belongs to the 'phage' integrase family
C7Y67_00140	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7Y67_00150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7Y67_00155	COG0250	Participates in transcription elongation, termination and antitermination
C7Y67_00160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7Y67_00165	COG0081	regulation of translation
C7Y67_00170	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7Y67_00175	COG0222	ribosome binding
C7Y67_00180	COG0085	RNA polymerase activity
C7Y67_00185	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7Y67_00190	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C7Y67_00195	COG2816	NAD+ diphosphatase activity
C7Y67_00210	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7Y67_00215	COG1573	uracil-dna glycosylase
C7Y67_00220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7Y67_00225	COG3068	Protein conserved in bacteria
C7Y67_00230	COG1253	flavin adenine dinucleotide binding
C7Y67_00245	COG0151	Belongs to the GarS family
C7Y67_00255	COG0138	bifunctional purine biosynthesis protein purh
C7Y67_00265	COG0789	Transcriptional regulator
C7Y67_00270	COG3710	Transcriptional regulator
C7Y67_00280	COG0531	amino acid
C7Y67_00285	COG1982	Orn Lys Arg decarboxylase major
C7Y67_00350	COG3706	GGDEF domain
C7Y67_00365	COG0488	(ABC) transporter
C7Y67_00370	COG2814	Major facilitator Superfamily
C7Y67_00380	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7Y67_00435	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C7Y67_00440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7Y67_00445	COG2264	protein methyltransferase activity
C7Y67_00455	COG0439	Biotin carboxylase
C7Y67_00460	COG0511	ligase activity, forming carbon-carbon bonds
C7Y67_00465	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7Y67_00470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7Y67_00485	COG2814	Major facilitator Superfamily
C7Y67_00490	COG2205	protein histidine kinase activity
C7Y67_00490	COG0784	Response regulator, receiver
C7Y67_00515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7Y67_00525	COG3263	regulation of cellular component size
C7Y67_00535	COG4232	protein-disulfide reductase activity
C7Y67_00540	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C7Y67_00545	COG1027	Aspartate ammonia-lyase
C7Y67_00550	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7Y67_00555	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7Y67_00565	COG2205	protein histidine kinase activity
C7Y67_00570	COG0745	RESPONSE REGULATOR receiver
C7Y67_00580	COG3678	ATP-independent chaperone mediated protein folding
C7Y67_00590	COG0205	6-phosphofructokinase activity
C7Y67_00595	COG0534	Mate efflux family protein
C7Y67_00600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7Y67_00605	COG0459	protein refolding
C7Y67_00615	COG1285	pathogenesis
C7Y67_00625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7Y67_00635	COG1509	lysine 2,3-aminomutase activity
C7Y67_00640	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7Y67_00650	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C7Y67_00655	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C7Y67_00660	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7Y67_00665	COG1053	succinate dehydrogenase
C7Y67_00675	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C7Y67_00695	COG4942	peptidase
C7Y67_00700	COG1045	serine acetyltransferase
C7Y67_00705	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7Y67_00710	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C7Y67_00715	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7Y67_00720	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7Y67_00735	COG0471	metal ion transport
C7Y67_00740	COG0688	phosphatidylethanolamine metabolic process
C7Y67_00745	COG1162	GTPase activity
C7Y67_00750	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C7Y67_00820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7Y67_00825	COG0802	atpase or kinase
C7Y67_00835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7Y67_00840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7Y67_00850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7Y67_00855	COG0330	HflC and HflK could
C7Y67_00860	COG0330	HflC and HflK could
C7Y67_00865	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C7Y67_00870	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7Y67_00880	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C7Y67_00885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7Y67_00885	COG1017	nitric oxide dioxygenase activity
C7Y67_00890	COG1959	2 iron, 2 sulfur cluster binding
C7Y67_00895	COG0557	exoribonuclease II activity
C7Y67_00900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7Y67_00905	COG0546	phosphoglycolate phosphatase activity
C7Y67_00910	COG0180	Tryptophanyl-tRNA synthetase
C7Y67_00940	COG0512	Glutamine amidotransferase of anthranilate synthase
C7Y67_00945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7Y67_00955	COG1012	belongs to the aldehyde dehydrogenase family
C7Y67_00965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7Y67_00970	COG3954	Phosphoribulokinase
C7Y67_00975	COG3089	Belongs to the UPF0270 family
C7Y67_00980	COG0429	hydrolase of the alpha beta-hydrolase fold
C7Y67_00990	COG0488	(ABC) transporter
C7Y67_01000	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7Y67_01015	COG1047	Peptidyl-prolyl cis-trans
C7Y67_01025	COG1446	asparaginase
C7Y67_01030	COG2900	Belongs to the SlyX family
C7Y67_01040	COG0545	Peptidyl-prolyl cis-trans isomerase
C7Y67_01045	COG2964	Protein conserved in bacteria
C7Y67_01050	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C7Y67_01055	COG2923	Belongs to the DsrF TusC family
C7Y67_01060	COG2168	tRNA wobble position uridine thiolation
C7Y67_01070	COG0049	tRNA binding
C7Y67_01075	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7Y67_01080	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7Y67_01085	COG2906	2 iron, 2 sulfur cluster binding
C7Y67_01095	COG0281	malic enzyme
C7Y67_01105	COG0626	cystathionine gamma-synthase activity
C7Y67_01110	COG0527	aspartate kinase activity
C7Y67_01110	COG0460	homoserine dehydrogenase
C7Y67_01115	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7Y67_01125	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C7Y67_01130	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7Y67_01135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7Y67_01140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7Y67_01145	COG0137	argininosuccinate synthase activity
C7Y67_01150	COG0165	Argininosuccinate lyase
C7Y67_01150	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7Y67_01165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7Y67_01165	COG0678	peroxiredoxin activity
C7Y67_01175	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C7Y67_01205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7Y67_01210	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7Y67_01220	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7Y67_01225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7Y67_01235	COG0360	Binds together with S18 to 16S ribosomal RNA
C7Y67_01240	COG2965	DNA replication, synthesis of RNA primer
C7Y67_01250	COG0359	binds to the 23S rRNA
C7Y67_01260	COG0305	Participates in initiation and elongation during chromosome replication
C7Y67_01265	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7Y67_01275	COG0432	Pfam Uncharacterised protein family UPF0047
C7Y67_01280	COG0166	Belongs to the GPI family
C7Y67_01290	COG0735	belongs to the Fur family
C7Y67_01300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7Y67_01325	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7Y67_01330	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7Y67_01335	COG0175	sulfate reduction
C7Y67_01405	COG3335	DDE superfamily endonuclease
C7Y67_01420	COG0646	methionine synthase
C7Y67_01420	COG1410	methionine synthase
C7Y67_01425	COG0527	aspartate kinase activity
C7Y67_01435	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7Y67_01445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7Y67_01460	COG0629	single-stranded DNA binding
C7Y67_01490	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7Y67_01510	COG2199	diguanylate cyclase activity
C7Y67_01510	COG2200	EAL domain
C7Y67_01535	COG3267	Type II secretory pathway component ExeA
C7Y67_01535	COG3409	Peptidoglycan-binding domain 1 protein
C7Y67_01545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7Y67_01550	COG1459	type II secretion system
C7Y67_01595	COG1077	Cell shape determining protein MreB Mrl
C7Y67_01600	COG1792	Involved in formation and maintenance of cell shape
C7Y67_01605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7Y67_01610	COG0424	maF-like protein
C7Y67_01615	COG1530	ribonuclease E activity
C7Y67_01620	COG3164	Protein of unknown function
C7Y67_01625	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7Y67_01630	COG0312	modulator of DNA gyrase
C7Y67_01635	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7Y67_01640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7Y67_01655	COG0564	pseudouridine synthase activity
C7Y67_01660	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7Y67_01665	COG3028	Belongs to the UPF0307 family
C7Y67_01670	COG0312	modulator of DNA gyrase
C7Y67_01675	COG2239	Acts as a magnesium transporter
C7Y67_01680	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7Y67_01685	COG1660	Displays ATPase and GTPase activities
C7Y67_01690	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7Y67_01695	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7Y67_01705	COG1137	ATPase activity
C7Y67_01710	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C7Y67_01720	COG0517	IMP dehydrogenase activity
C7Y67_01720	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7Y67_01730	COG1127	ABC transporter
C7Y67_01735	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7Y67_01740	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C7Y67_01745	COG2854	intermembrane phospholipid transfer
C7Y67_01755	COG5007	Belongs to the BolA IbaG family
C7Y67_01760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7Y67_01765	COG0204	Acyl-transferase
C7Y67_01770	COG0251	oxidation-reduction process
C7Y67_01775	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
C7Y67_01780	COG0540	Belongs to the ATCase OTCase family
C7Y67_01790	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7Y67_01795	COG2235	arginine
C7Y67_01875	COG0525	valine-tRNA ligase activity
C7Y67_01880	COG2927	DNA polymerase III (CHI subunit)
C7Y67_01885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7Y67_01890	COG0795	lipopolysaccharide-transporting ATPase activity
C7Y67_01895	COG0795	lipopolysaccharide-transporting ATPase activity
C7Y67_01905	COG4325	translation initiation factor activity
C7Y67_01910	COG1028	Short-chain dehydrogenase reductase Sdr
C7Y67_01925	COG0726	polysaccharide deacetylase
C7Y67_01930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7Y67_01935	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7Y67_01940	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7Y67_01945	COG1486	melibiose metabolic process
C7Y67_01950	COG3394	polysaccharide catabolic process
C7Y67_01960	COG3437	response regulator, receiver
C7Y67_02010	COG1012	belongs to the aldehyde dehydrogenase family
C7Y67_02040	COG0840	transmembrane signaling receptor activity
C7Y67_02080	COG0741	lytic transglycosylase activity
C7Y67_02085	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
C7Y67_02095	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7Y67_02105	COG2066	Belongs to the glutaminase family
C7Y67_02110	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7Y67_02115	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7Y67_02125	COG1872	DUF167
C7Y67_02130	COG0762	integral membrane protein
C7Y67_02135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7Y67_02140	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7Y67_02155	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7Y67_02160	COG1678	Uncharacterized ACR, COG1678
C7Y67_02165	COG0189	ligase activity
C7Y67_02170	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7Y67_02175	COG2356	endonuclease I
C7Y67_02180	COG3091	SprT-like family
C7Y67_02190	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C7Y67_02200	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7Y67_02205	COG0583	DNA-binding transcription factor activity
C7Y67_02210	COG4771	TonB-dependent receptor
C7Y67_02215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7Y67_02220	COG0126	phosphoglycerate kinase activity
C7Y67_02225	COG0191	fructose-bisphosphate aldolase activity
C7Y67_02230	COG0668	transmembrane transport
C7Y67_02235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7Y67_02245	COG0583	DNA-binding transcription factor activity
C7Y67_02255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7Y67_02260	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7Y67_02265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7Y67_02275	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C7Y67_02285	COG3079	Belongs to the UPF0149 family
C7Y67_02290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7Y67_02295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7Y67_02310	COG0354	folic acid binding
C7Y67_02315	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C7Y67_02325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7Y67_02335	COG1595	DNA-templated transcription, initiation
C7Y67_02340	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C7Y67_02350	COG3086	response to oxidative stress
C7Y67_02355	COG0481	GTPase activity
C7Y67_02360	COG0681	Belongs to the peptidase S26 family
C7Y67_02365	COG0571	ribonuclease III activity
C7Y67_02370	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7Y67_02375	COG1381	Involved in DNA repair and RecF pathway recombination
C7Y67_02380	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C7Y67_02385	COG0736	holo-[acyl-carrier-protein] synthase activity
C7Y67_02400	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7Y67_02410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7Y67_02415	COG3956	TIGRFAM MazG family protein
C7Y67_02420	COG0504	CTP synthase activity
C7Y67_02425	COG0148	phosphopyruvate hydratase activity
C7Y67_02430	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7Y67_02435	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7Y67_02440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C7Y67_02445	COG0585	pseudouridine synthase activity
C7Y67_02450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C7Y67_02455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C7Y67_02470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7Y67_02475	COG1546	Belongs to the CinA family
C7Y67_02485	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7Y67_02550	COG2137	regulation of response to DNA damage stimulus
C7Y67_02555	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7Y67_02560	COG0527	aspartate kinase activity
C7Y67_02620	COG3630	sodium ion export across plasma membrane
C7Y67_02625	COG5016	pyruvate
C7Y67_02625	COG0511	ligase activity, forming carbon-carbon bonds
C7Y67_02630	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C7Y67_02635	COG1063	alcohol dehydrogenase
C7Y67_02640	COG1238	metal cluster binding
C7Y67_02645	COG0612	Peptidase, M16
C7Y67_02650	COG2918	glutathione biosynthetic process
C7Y67_02660	COG1854	S-ribosylhomocysteine lyase activity
C7Y67_02665	COG4536	flavin adenine dinucleotide binding
C7Y67_02670	COG4137	Cytochrome C assembly protein
C7Y67_02675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7Y67_02680	COG0228	four-way junction DNA binding
C7Y67_02685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7Y67_02700	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C7Y67_02705	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C7Y67_02710	COG0237	dephospho-CoA kinase activity
C7Y67_02720	COG1459	type II secretion system
C7Y67_02725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7Y67_02735	COG0157	Belongs to the NadC ModD family
C7Y67_02745	COG2186	Transcriptional regulator
C7Y67_02750	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C7Y67_02755	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7Y67_02760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7Y67_02775	COG0288	reversible hydration of carbon dioxide
C7Y67_02780	COG0659	secondary active sulfate transmembrane transporter activity
C7Y67_02790	COG1131	(ABC) transporter
C7Y67_02795	COG0842	Transport permease protein
C7Y67_02805	COG1560	Kdo2-lipid A biosynthetic process
C7Y67_02815	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7Y67_02820	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7Y67_02825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7Y67_02840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7Y67_02850	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7Y67_02855	COG1489	DNA binding
C7Y67_02895	COG3550	peptidyl-serine autophosphorylation
C7Y67_02965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7Y67_02970	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7Y67_02975	COG1049	propionate catabolic process, 2-methylcitrate cycle
C7Y67_02980	COG3112	Uncharacterised protein family (UPF0231)
C7Y67_02990	COG0004	ammonium transporteR
C7Y67_02995	COG1840	ABC-type Fe3 transport system, periplasmic component
C7Y67_03005	COG3842	ATPase activity
C7Y67_03010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7Y67_03025	COG2971	BadF BadG BcrA BcrD
C7Y67_03035	COG4608	Belongs to the ABC transporter superfamily
C7Y67_03040	COG0444	Belongs to the ABC transporter superfamily
C7Y67_03045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7Y67_03055	COG0747	negative chemotaxis
C7Y67_03060	COG0784	Response regulator, receiver
C7Y67_03060	COG2205	protein histidine kinase activity
C7Y67_03060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7Y67_03060	COG2198	Histidine kinase
C7Y67_03070	COG2813	Specifically methylates the guanine in position
C7Y67_03075	COG0628	permease
C7Y67_03080	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7Y67_03085	COG0316	Belongs to the HesB IscA family
C7Y67_03095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7Y67_03100	COG0739	heme binding
C7Y67_03105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7Y67_03115	COG2027	D-alanyl-D-alanine carboxypeptidase
C7Y67_03120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C7Y67_03125	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7Y67_03130	COG1534	Rna-binding protein
C7Y67_03135	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C7Y67_03140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7Y67_03145	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7Y67_03150	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7Y67_03160	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7Y67_03175	COG0779	Required for maturation of 30S ribosomal subunits
C7Y67_03180	COG0195	Participates in both transcription termination and antitermination
C7Y67_03185	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7Y67_03190	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7Y67_03195	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7Y67_03200	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7Y67_03205	COG1185	polyribonucleotide nucleotidyltransferase activity
C7Y67_03210	COG4785	May be involved in cell division
C7Y67_03220	COG0534	Mate efflux family protein
C7Y67_03245	COG3153	acetyltransferase
C7Y67_03265	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7Y67_03275	COG0084	hydrolase, TatD family'
C7Y67_03280	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7Y67_03285	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7Y67_03290	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7Y67_03295	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7Y67_03300	COG0813	purine-nucleoside phosphorylase activity
C7Y67_03310	COG0560	Phosphoserine phosphatase
C7Y67_03320	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7Y67_03325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7Y67_03330	COG0583	DNA-binding transcription factor activity
C7Y67_03340	COG1022	Amp-dependent synthetase and ligase
C7Y67_03345	COG2169	Transcriptional regulator
C7Y67_03370	COG4964	Belongs to the GSP D family
C7Y67_03430	COG0583	DNA-binding transcription factor activity
C7Y67_03435	COG0531	amino acid
C7Y67_03440	COG2731	YhcH YjgK YiaL family protein
C7Y67_03445	COG3250	beta-galactosidase activity
C7Y67_03450	COG1609	Transcriptional regulator
C7Y67_03460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7Y67_03470	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7Y67_03475	COG2017	converts alpha-aldose to the beta-anomer
C7Y67_03490	COG2211	Major facilitator Superfamily
C7Y67_03495	COG1609	Transcriptional regulator
C7Y67_03500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7Y67_03515	COG0598	Magnesium transport protein CorA
C7Y67_03520	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7Y67_03525	COG1349	DNA-binding transcription factor activity
C7Y67_03530	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7Y67_03535	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7Y67_03550	COG2271	Major facilitator Superfamily
C7Y67_03555	COG0584	glycerophosphoryl diester phosphodiesterase
C7Y67_03560	COG2171	N-acyltransferase activity
C7Y67_03565	COG3141	response to X-ray
C7Y67_03585	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C7Y67_03595	COG1074	ATP-dependent DNA helicase activity
C7Y67_03600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7Y67_03610	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7Y67_03610	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7Y67_03625	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C7Y67_03630	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7Y67_03635	COG2166	iron-sulfur cluster assembly
C7Y67_03640	COG3706	GGDEF domain
C7Y67_03645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7Y67_03650	COG0693	protein deglycase activity
C7Y67_03655	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7Y67_03680	COG1595	DNA-templated transcription, initiation
C7Y67_03700	COG3056	Lipoprotein
C7Y67_03705	COG2813	Specifically methylates the guanine in position
C7Y67_03710	COG0271	Belongs to the BolA IbaG family
C7Y67_03720	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7Y67_03725	COG1805	sodium ion transport
C7Y67_03730	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7Y67_03735	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7Y67_03740	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7Y67_03745	COG2871	sodium ion transport
C7Y67_03750	COG1477	protein flavinylation
C7Y67_03765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7Y67_03770	COG0514	ATP-dependent DNA helicase (RecQ)
C7Y67_03790	COG0733	neurotransmitter:sodium symporter activity
C7Y67_03810	COG0442	prolyl-tRNA aminoacylation
C7Y67_03815	COG1720	tRNA m6t6A37 methyltransferase activity
C7Y67_03820	COG0254	rRNA binding
C7Y67_03835	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C7Y67_03840	COG1671	Belongs to the UPF0178 family
C7Y67_03865	COG3098	single-species biofilm formation
C7Y67_03870	COG0564	pseudouridine synthase activity
C7Y67_03880	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C7Y67_03885	COG0024	Methionine aminopeptidase
C7Y67_03890	COG0052	Belongs to the universal ribosomal protein uS2 family
C7Y67_03895	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7Y67_03900	COG0528	UMP kinase activity
C7Y67_03905	COG0233	cytoplasmic translational termination
C7Y67_03910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7Y67_03915	COG0575	Belongs to the CDS family
C7Y67_03920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7Y67_03925	COG0750	zinc metalloprotease
C7Y67_03935	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C7Y67_03940	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7Y67_03945	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7Y67_03950	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7Y67_03955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7Y67_03960	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7Y67_03965	COG0587	DNA-directed DNA polymerase activity
C7Y67_03970	COG0825	malonyl-CoA metabolic process
C7Y67_03975	COG0037	tRNA processing
C7Y67_03985	COG0347	Belongs to the P(II) protein family
C7Y67_03990	COG3021	interspecies interaction between organisms
C7Y67_04000	COG0741	lytic transglycosylase activity
C7Y67_04000	COG1388	LysM domain
C7Y67_04005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7Y67_04010	COG2226	methyltransferase
C7Y67_04015	COG0328	RNA-DNA hybrid ribonuclease activity
C7Y67_04020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7Y67_04050	COG1960	acyl-CoA dehydrogenase activity
C7Y67_04055	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C7Y67_04060	COG0121	glutamine amidotransferase
C7Y67_04065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7Y67_04070	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7Y67_04075	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7Y67_04080	COG2233	PERMEase
C7Y67_04100	COG1393	Belongs to the ArsC family
C7Y67_04105	COG4783	chaperone-mediated protein folding
C7Y67_04120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7Y67_04125	COG2716	regulation of RNA biosynthetic process
C7Y67_04130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7Y67_04150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7Y67_04155	COG1393	Belongs to the ArsC family
C7Y67_04185	COG2837	iron assimilation
C7Y67_04190	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7Y67_04200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7Y67_04205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7Y67_04210	COG1334	flagellar protein FlaG
C7Y67_04215	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7Y67_04225	COG1516	flagellar protein fliS
C7Y67_04235	COG4191	Histidine kinase
C7Y67_04240	COG2204	response regulator
C7Y67_04245	COG1677	Flagellar hook-basal body complex protein FliE
C7Y67_04255	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7Y67_04305	COG1987	bacterial-type flagellum assembly
C7Y67_04330	COG0455	bacterial-type flagellum organization
C7Y67_04345	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C7Y67_04350	COG2198	Histidine kinase
C7Y67_04350	COG0643	Histidine kinase
C7Y67_04355	COG2201	protein-glutamate methylesterase activity
C7Y67_04360	COG1192	Involved in chromosome partitioning
C7Y67_04370	COG0835	chemotaxis
C7Y67_04380	COG4133	protoheme IX ABC transporter activity
C7Y67_04385	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7Y67_04390	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7Y67_04395	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7Y67_04400	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C7Y67_04405	COG1138	Cytochrome C-type biogenesis protein
C7Y67_04410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7Y67_04425	COG2853	Lipoprotein
C7Y67_04435	COG2067	long-chain fatty acid transport protein
C7Y67_04455	COG0183	Belongs to the thiolase family
C7Y67_04460	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7Y67_04460	COG1024	Enoyl-CoA hydratase
C7Y67_04475	COG2062	phosphohistidine phosphatase, SixA
C7Y67_04480	COG2840	Smr protein MutS2
C7Y67_04485	COG2890	protein-(glutamine-N5) methyltransferase activity
C7Y67_04490	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7Y67_04495	COG2860	membrane
C7Y67_04505	COG3101	peptidyl-lysine hydroxylation
C7Y67_04520	COG0431	NADPH-dependent FMN reductase
C7Y67_04525	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C7Y67_04525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7Y67_04530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7Y67_04540	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7Y67_04545	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7Y67_04555	COG0101	tRNA pseudouridine synthase activity
C7Y67_04560	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7Y67_04565	COG0285	dihydrofolate synthase activity
C7Y67_04570	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C7Y67_04575	COG1286	toxin biosynthetic process
C7Y67_04580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7Y67_04585	COG0583	DNA-binding transcription factor activity
C7Y67_04590	COG0745	RESPONSE REGULATOR receiver
C7Y67_04600	COG2832	Protein of unknown function (DUF454)
C7Y67_04605	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7Y67_04615	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7Y67_04620	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7Y67_04625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7Y67_04630	COG0814	amino acid
C7Y67_04635	COG0251	oxidation-reduction process
C7Y67_04640	COG3681	Belongs to the UPF0597 family
C7Y67_04655	COG2261	transglycosylase associated protein
C7Y67_04660	COG2983	Belongs to the UPF0260 family
C7Y67_04665	COG0668	transmembrane transport
C7Y67_04670	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7Y67_04675	COG0346	lactoylglutathione lyase activity
C7Y67_04685	COG1785	Belongs to the alkaline phosphatase family
C7Y67_04705	COG2226	methyltransferase
C7Y67_04720	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7Y67_04725	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7Y67_04735	COG3139	Protein of unknown function (DUF1315)
C7Y67_04740	COG0252	asparaginase activity
C7Y67_04745	COG0616	signal peptide processing
C7Y67_04750	COG1902	pentaerythritol trinitrate reductase activity
C7Y67_04750	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7Y67_04755	COG0778	Nitroreductase
C7Y67_04760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7Y67_04780	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7Y67_04790	COG3083	sulfuric ester hydrolase activity
C7Y67_04795	COG3082	Protein of unknown function (DUF1414)
C7Y67_04800	COG3081	Nucleoid-associated protein
C7Y67_04815	COG1757	Na H antiporter
C7Y67_04820	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7Y67_04825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7Y67_04830	COG2095	MarC family integral membrane protein
C7Y67_04835	COG1454	alcohol dehydrogenase
C7Y67_04835	COG1012	belongs to the aldehyde dehydrogenase family
C7Y67_04855	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C7Y67_04865	COG2056	Na+-H+ antiporter family
C7Y67_04870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7Y67_04885	COG2885	chlorophyll binding
C7Y67_04895	COG0346	lactoylglutathione lyase activity
C7Y67_04900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7Y67_04905	COG4660	Part of a membrane complex involved in electron transport
C7Y67_04910	COG4659	FMN binding
C7Y67_04915	COG4658	electron transport chain
C7Y67_04920	COG4656	Part of a membrane complex involved in electron transport
C7Y67_04925	COG2878	Part of a membrane complex involved in electron transport
C7Y67_04930	COG4657	Part of a membrane complex involved in electron transport
C7Y67_04945	COG0556	nucleotide-excision repair
C7Y67_04950	COG2204	response regulator
C7Y67_04955	COG2198	Histidine kinase
C7Y67_04960	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7Y67_04965	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7Y67_04970	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7Y67_04975	COG0315	cyclic pyranopterin monophosphate synthase activity
C7Y67_04980	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7Y67_04985	COG0314	molybdopterin synthase activity
C7Y67_04995	COG0601	transmembrane transport
C7Y67_05000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7Y67_05005	COG0444	Belongs to the ABC transporter superfamily
C7Y67_05015	COG0435	Glutathione S-transferase
C7Y67_05025	COG3174	membrane
C7Y67_05030	COG0280	phosphate acetyltransferase
C7Y67_05030	COG0857	belongs to the CobB CobQ family
C7Y67_05035	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7Y67_05040	COG3092	negative regulation of chromosome organization
C7Y67_05050	COG4120	Belongs to the binding-protein-dependent transport system permease family
C7Y67_05055	COG1122	ATPase activity
C7Y67_05060	COG0366	Alpha amylase catalytic
C7Y67_05065	COG3706	GGDEF domain
C7Y67_05065	COG0745	RESPONSE REGULATOR receiver
C7Y67_05070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7Y67_05075	COG0653	protein targeting
C7Y67_05080	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7Y67_05085	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C7Y67_05090	COG2186	Transcriptional regulator
C7Y67_05100	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7Y67_05100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7Y67_05105	COG0489	protein tyrosine kinase activity
C7Y67_05110	COG0572	uridine kinase
C7Y67_05120	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C7Y67_05125	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7Y67_05130	COG0659	secondary active sulfate transmembrane transporter activity
C7Y67_05140	COG1530	ribonuclease E activity
C7Y67_05155	COG0564	pseudouridine synthase activity
C7Y67_05160	COG0424	maF-like protein
C7Y67_05165	COG1399	metal-binding, possibly nucleic acid-binding protein
C7Y67_05175	COG0416	fatty acid biosynthetic process
C7Y67_05180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7Y67_05210	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7Y67_05215	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7Y67_05225	COG0084	hydrolase, TatD family'
C7Y67_05230	COG1263	PTS System
C7Y67_05230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7Y67_05250	COG0733	neurotransmitter:sodium symporter activity
C7Y67_05265	COG4667	esterase of the alpha-beta hydrolase superfamily
C7Y67_05270	COG0469	pyruvate kinase activity
C7Y67_05275	COG1940	carbohydrate kinase activity
C7Y67_05280	COG0835	chemotaxis
C7Y67_05280	COG0784	Response regulator, receiver
C7Y67_05285	COG0587	DNA-directed DNA polymerase activity
C7Y67_05300	COG1028	Short-chain dehydrogenase reductase Sdr
C7Y67_05305	COG0616	signal peptide processing
C7Y67_05310	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7Y67_05315	COG0539	negative regulation of cytoplasmic translation
C7Y67_05325	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C7Y67_05330	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C7Y67_05335	COG0284	orotidine-5'-phosphate decarboxylase activity
C7Y67_05340	COG4166	transmembrane transport
C7Y67_05365	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7Y67_05375	COG3008	intermembrane lipid transfer
C7Y67_05375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C7Y67_05380	COG2995	paraquat-inducible protein a
C7Y67_05385	COG3258	Cytochrome c
C7Y67_05390	COG2863	cytochrome
C7Y67_05430	COG4232	protein-disulfide reductase activity
C7Y67_05435	COG3118	belongs to the thioredoxin family
C7Y67_05465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7Y67_05475	COG0577	efflux transmembrane transporter activity
C7Y67_05475	COG1136	(ABC) transporter
C7Y67_05480	COG1136	(ABC) transporter
C7Y67_05480	COG0577	efflux transmembrane transporter activity
C7Y67_05485	COG1136	(ABC) transporter
C7Y67_05485	COG0577	efflux transmembrane transporter activity
C7Y67_05490	COG1335	isochorismatase
C7Y67_05505	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7Y67_05540	COG3850	Histidine kinase
C7Y67_05540	COG5002	protein histidine kinase activity
C7Y67_05545	COG0745	RESPONSE REGULATOR receiver
C7Y67_05555	COG0840	transmembrane signaling receptor activity
C7Y67_05560	COG1032	radical SAM domain protein
C7Y67_05565	COG5001	Diguanylate cyclase
C7Y67_05565	COG4251	negative regulation of phosphorylation
C7Y67_05565	COG3706	GGDEF domain
C7Y67_05565	COG2203	Gaf domain
C7Y67_05580	COG0583	DNA-binding transcription factor activity
C7Y67_05590	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7Y67_05600	COG2350	Protein conserved in bacteria
C7Y67_05605	COG1607	acyl-coa hydrolase
C7Y67_05610	COG2917	probably involved in intracellular septation
C7Y67_05630	COG1301	dicarboxylic acid transport
C7Y67_05640	COG0318	PFAM AMP-dependent synthetase and ligase
C7Y67_05645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7Y67_05650	COG0159	tryptophan synthase activity
C7Y67_05655	COG0133	tryptophan synthase activity
C7Y67_05660	COG0135	phosphoribosylanthranilate isomerase activity
C7Y67_05660	COG0134	indole-3-glycerol-phosphate synthase activity
C7Y67_05665	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7Y67_05670	COG0512	Glutamine amidotransferase of anthranilate synthase
C7Y67_05675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7Y67_05685	COG0613	PHP domain protein
C7Y67_05690	COG0009	L-threonylcarbamoyladenylate synthase
C7Y67_05700	COG1187	pseudouridine synthase activity
C7Y67_05710	COG3099	Belongs to the UPF0263 family
C7Y67_05715	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7Y67_05725	COG0417	DNA replication proofreading
C7Y67_05730	COG2197	response regulator
C7Y67_05735	COG0322	excinuclease ABC activity
C7Y67_05775	COG0019	diaminopimelate decarboxylase activity
C7Y67_05800	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7Y67_05805	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7Y67_05810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7Y67_05830	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C7Y67_05840	COG0437	4 iron, 4 sulfur cluster binding
C7Y67_05845	COG3301	Polysulphide reductase, NrfD
C7Y67_05850	COG1138	Cytochrome C-type biogenesis protein
C7Y67_05860	COG4235	cytochrome complex assembly
C7Y67_05860	COG3088	subunit of a heme lyase
C7Y67_05870	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7Y67_05895	COG2989	Protein conserved in bacteria
C7Y67_05900	COG3108	Peptidase M15
C7Y67_05905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7Y67_05920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C7Y67_05945	COG1846	Transcriptional regulator
C7Y67_05950	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7Y67_05955	COG0840	transmembrane signaling receptor activity
C7Y67_05975	COG1448	Aminotransferase
C7Y67_06000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7Y67_06010	COG0017	Asparaginyl-tRNA synthetase
C7Y67_06020	COG0720	synthase
C7Y67_06030	COG2200	EAL domain
C7Y67_06035	COG1760	l-serine dehydratase
C7Y67_06040	COG0814	amino acid
C7Y67_06045	COG0494	nUDIX hydrolase
C7Y67_06055	COG0784	Response regulator, receiver
C7Y67_06055	COG2205	protein histidine kinase activity
C7Y67_06060	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7Y67_06080	COG3106	COG3106 Predicted ATPase
C7Y67_06085	COG3768	UPF0283 membrane protein
C7Y67_06095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7Y67_06135	COG2801	Transposase and inactivated derivatives
C7Y67_06235	COG2732	(Barnase) inhibitor
C7Y67_06275	COG0346	lactoylglutathione lyase activity
C7Y67_06570	COG0346	lactoylglutathione lyase activity
C7Y67_06780	COG2161	toxin-antitoxin pair type II binding
C7Y67_06785	COG4115	mRNA cleavage
C7Y67_06850	COG1757	Na H antiporter
C7Y67_06855	COG0174	glutamine synthetase
C7Y67_06865	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7Y67_06870	COG1396	sequence-specific DNA binding
C7Y67_06870	COG1917	Cupin 2, conserved barrel domain protein
C7Y67_06875	COG1012	belongs to the aldehyde dehydrogenase family
C7Y67_06880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7Y67_06890	COG2957	Belongs to the agmatine deiminase family
C7Y67_06895	COG1012	belongs to the aldehyde dehydrogenase family
C7Y67_06900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7Y67_06905	COG1227	inorganic diphosphatase activity
C7Y67_06915	COG2200	EAL domain
C7Y67_06915	COG2771	luxR family
C7Y67_06940	COG1846	Transcriptional regulator
C7Y67_06945	COG2315	Protein conserved in bacteria
C7Y67_06965	COG0110	maltose O-acetyltransferase activity
C7Y67_06995	COG3063	Type IV pilus biogenesis stability protein PilW
C7Y67_07000	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7Y67_07015	COG0531	amino acid
C7Y67_07025	COG1560	Kdo2-lipid A biosynthetic process
C7Y67_07030	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7Y67_07035	COG1280	lysine exporter protein (LysE YggA)
C7Y67_07045	COG1115	amino acid carrier protein
C7Y67_07070	COG1368	sulfuric ester hydrolase activity
C7Y67_07075	COG0642	Histidine kinase
C7Y67_07080	COG0745	RESPONSE REGULATOR receiver
C7Y67_07090	COG1028	Short-chain dehydrogenase reductase Sdr
C7Y67_07100	COG1022	Amp-dependent synthetase and ligase
C7Y67_07110	COG2113	Glycine betaine
C7Y67_07115	COG4176	ABC-type proline glycine betaine transport system permease component
C7Y67_07135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7Y67_07140	COG0456	acetyltransferase
C7Y67_07145	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7Y67_07150	COG0662	Cupin 2, conserved barrel domain protein
C7Y67_07155	COG0527	aspartate kinase activity
C7Y67_07170	COG1858	cytochrome C peroxidase
C7Y67_07185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7Y67_07200	COG3290	protein histidine kinase activity
C7Y67_07205	COG4565	transcriptional regulatory protein
C7Y67_07210	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C7Y67_07215	COG0363	glucosamine-6-phosphate deaminase activity
C7Y67_07220	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C7Y67_07235	COG3284	Transcriptional regulator
C7Y67_07240	COG1012	belongs to the aldehyde dehydrogenase family
C7Y67_07310	COG4669	(LipO)protein
C7Y67_07330	COG3177	Filamentation induced by cAMP protein fic
C7Y67_07380	COG4792	protein secretion
C7Y67_07385	COG4791	protein targeting
C7Y67_07390	COG4794	Type iii secretion
C7Y67_07395	COG4790	Type iii secretion
C7Y67_07400	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7Y67_07465	COG0457	Tetratricopeptide repeat
C7Y67_07485	COG0730	response to heat
C7Y67_07515	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7Y67_07520	COG0372	Belongs to the citrate synthase family
C7Y67_07530	COG2828	Protein conserved in bacteria
C7Y67_07540	COG0456	acetyltransferase
C7Y67_07555	COG0561	phosphatase activity
C7Y67_07560	COG0602	queuosine metabolic process
C7Y67_07565	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7Y67_07570	COG3706	GGDEF domain
C7Y67_07610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7Y67_07615	COG0840	transmembrane signaling receptor activity
C7Y67_07620	COG1254	Belongs to the acylphosphatase family
C7Y67_07625	COG2920	part of a sulfur-relay system
C7Y67_07635	COG0670	Belongs to the BI1 family
C7Y67_07640	COG1126	abc transporter atp-binding protein
C7Y67_07645	COG0765	amino acid transport
C7Y67_07650	COG4597	amino acid ABC transporter
C7Y67_07655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7Y67_07675	COG1666	GTP binding
C7Y67_07680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C7Y67_07700	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C7Y67_07700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7Y67_07710	COG3008	intermembrane lipid transfer
C7Y67_07715	COG2995	paraquat-inducible protein a
C7Y67_07720	COG1132	(ABC) transporter
C7Y67_07725	COG1956	GAF domain-containing protein
C7Y67_07730	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C7Y67_07745	COG0308	aminopeptidase N
C7Y67_07755	COG2902	Dehydrogenase
C7Y67_07760	COG0167	dihydroorotate dehydrogenase activity
C7Y67_07775	COG0116	Belongs to the methyltransferase superfamily
C7Y67_07775	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7Y67_07800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7Y67_07805	COG1067	ATP-dependent peptidase activity
C7Y67_07810	COG3120	sequence-specific DNA binding
C7Y67_07965	COG3278	Belongs to the heme-copper respiratory oxidase family
C7Y67_07980	COG2010	Cytochrome c
C7Y67_07990	COG2217	Heavy metal translocating P-type atpase
C7Y67_08005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7Y67_08010	COG0589	response to stress
C7Y67_08020	COG0037	tRNA processing
C7Y67_08040	COG3842	ATPase activity
C7Y67_08045	COG1176	ABC-type spermidine putrescine transport system, permease component I
C7Y67_08050	COG1177	transmembrane transport
C7Y67_08055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C7Y67_08060	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C7Y67_08065	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7Y67_08070	COG0004	ammonium transporteR
C7Y67_08125	COG0437	4 iron, 4 sulfur cluster binding
C7Y67_08130	COG0243	molybdopterin cofactor binding
C7Y67_08130	COG3383	formate dehydrogenase (NAD+) activity
C7Y67_08140	COG3381	protein complex oligomerization
C7Y67_08165	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7Y67_08170	COG0488	(ABC) transporter
C7Y67_08180	COG4191	Histidine kinase
C7Y67_08185	COG2204	response regulator
C7Y67_08205	COG3842	ATPase activity
C7Y67_08210	COG0746	molybdenum cofactor guanylyltransferase activity
C7Y67_08215	COG0303	'Molybdopterin
C7Y67_08225	COG1940	carbohydrate kinase activity
C7Y67_08265	COG3290	protein histidine kinase activity
C7Y67_08265	COG0840	transmembrane signaling receptor activity
C7Y67_08270	COG0791	NLP P60 protein
C7Y67_08280	COG3706	GGDEF domain
C7Y67_08285	COG2201	protein-glutamate methylesterase activity
C7Y67_08300	COG0307	riboflavin synthase, alpha
C7Y67_08305	COG0534	Mate efflux family protein
C7Y67_08315	COG1793	dna ligase
C7Y67_08350	COG2204	response regulator
C7Y67_08395	COG0438	transferase activity, transferring glycosyl groups
C7Y67_08400	COG1215	transferase activity, transferring glycosyl groups
C7Y67_08405	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7Y67_08415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7Y67_08430	COG1643	Atp-dependent helicase
C7Y67_08435	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7Y67_08445	COG3381	protein complex oligomerization
C7Y67_08450	COG3302	dmso reductase anchor subunit
C7Y67_08455	COG0437	4 iron, 4 sulfur cluster binding
C7Y67_08460	COG0243	molybdopterin cofactor binding
C7Y67_08490	COG3706	GGDEF domain
C7Y67_08500	COG0443	Heat shock 70 kDa protein
C7Y67_08505	COG0443	Heat shock 70 kDa protein
C7Y67_08535	COG1132	(ABC) transporter
C7Y67_08540	COG1132	(ABC) transporter
C7Y67_08565	COG0814	amino acid
C7Y67_08580	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C7Y67_08675	COG1522	sequence-specific DNA binding
C7Y67_08710	COG0515	serine threonine protein kinase
C7Y67_08735	COG3501	Rhs element vgr protein
C7Y67_08755	COG2885	chlorophyll binding
C7Y67_08775	COG0739	heme binding
C7Y67_08785	COG0861	Integral membrane protein TerC family
C7Y67_08795	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7Y67_08800	COG1328	CTP reductase activity
C7Y67_08805	COG1280	lysine exporter protein (LysE YggA)
C7Y67_08815	COG3300	MHYT domain
C7Y67_08815	COG5001	Diguanylate cyclase
C7Y67_08825	COG4191	Histidine kinase
C7Y67_08825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7Y67_08830	COG0471	metal ion transport
C7Y67_08865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7Y67_08870	COG0583	DNA-binding transcription factor activity
C7Y67_08885	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C7Y67_08890	COG1982	Orn Lys Arg decarboxylase major
C7Y67_08895	COG1982	Orn Lys Arg decarboxylase major
C7Y67_08900	COG0531	amino acid
C7Y67_08910	COG0531	amino acid
C7Y67_08940	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C7Y67_08940	COG3264	Mechanosensitive ion channel
C7Y67_08955	COG1127	ABC transporter
C7Y67_08960	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7Y67_09000	COG0625	glutathione transferase activity
C7Y67_09010	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C7Y67_09025	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7Y67_09035	COG0601	transmembrane transport
C7Y67_09040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7Y67_09045	COG0444	Belongs to the ABC transporter superfamily
C7Y67_09065	COG3291	Pkd domain containing protein
C7Y67_09080	COG1177	transmembrane transport
C7Y67_09085	COG1176	ABC-type spermidine putrescine transport system, permease component I
C7Y67_09090	COG3842	ATPase activity
C7Y67_09095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7Y67_09100	COG2423	ornithine cyclodeaminase activity
C7Y67_09120	COG3938	Belongs to the proline racemase family
C7Y67_09150	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C7Y67_09155	COG1451	nucleotide metabolic process
C7Y67_09160	COG3475	LICD family
C7Y67_09165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7Y67_09170	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7Y67_09190	COG0583	DNA-binding transcription factor activity
C7Y67_09210	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
C7Y67_09215	COG4139	cobalamin transport
C7Y67_09220	COG2988	succinylglutamate desuccinylase activity
C7Y67_09235	COG2062	phosphohistidine phosphatase, SixA
C7Y67_09245	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C7Y67_09250	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C7Y67_09255	COG0702	epimerase
C7Y67_09265	COG2925	Exonuclease
C7Y67_09270	COG1380	Effector of murein hydrolase LrgA
C7Y67_09275	COG1346	cytolysis
C7Y67_09280	COG0295	cytidine deaminase activity
C7Y67_09285	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7Y67_09290	COG0500	methyltransferase
C7Y67_09300	COG0776	regulation of translation
C7Y67_09315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7Y67_09315	COG0072	phenylalanine-tRNA ligase activity
C7Y67_09320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7Y67_09325	COG3706	GGDEF domain
C7Y67_09355	COG0393	Putative heavy-metal-binding
C7Y67_09365	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7Y67_09375	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7Y67_09390	COG2188	Transcriptional regulator
C7Y67_09395	COG1228	amidohydrolase
C7Y67_09400	COG0010	Belongs to the arginase family
C7Y67_09405	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C7Y67_09410	COG2986	histidine ammonia-lyase
C7Y67_09425	COG0247	lactate metabolic process
C7Y67_09425	COG0277	FAD linked oxidase domain protein
C7Y67_09460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7Y67_09475	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C7Y67_09480	COG1643	Atp-dependent helicase
C7Y67_09485	COG0281	malic enzyme
C7Y67_09490	COG2949	membrane
C7Y67_09495	COG0471	metal ion transport
C7Y67_09500	COG0745	RESPONSE REGULATOR receiver
C7Y67_09500	COG3706	GGDEF domain
C7Y67_09520	COG0492	ferredoxin-NADP+ reductase activity
C7Y67_09525	COG4988	ABC transporter
C7Y67_09530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7Y67_09535	COG3048	D-serine ammonia-lyase activity
C7Y67_09540	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7Y67_09550	COG4191	Histidine kinase
C7Y67_09550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7Y67_09565	COG3070	regulator of competence-specific genes
C7Y67_09585	COG2431	L-lysine efflux transmembrane transporter activity
C7Y67_09595	COG0076	glutamate decarboxylase activity
C7Y67_09600	COG1737	Transcriptional regulator
C7Y67_09615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7Y67_09620	COG3273	potassium ion transport
C7Y67_09620	COG2985	domain, Protein
C7Y67_09625	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7Y67_09640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C7Y67_09655	COG4181	ATPase activity
C7Y67_09660	COG0534	Mate efflux family protein
C7Y67_09665	COG0702	epimerase
C7Y67_09670	COG3005	denitrification pathway
C7Y67_09700	COG2814	Major facilitator Superfamily
C7Y67_09705	COG1187	pseudouridine synthase activity
C7Y67_09710	COG1061	Type III restriction enzyme res subunit
C7Y67_09720	COG0745	RESPONSE REGULATOR receiver
C7Y67_09725	COG2205	protein histidine kinase activity
C7Y67_09730	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7Y67_09760	COG3313	Fe-S protein
C7Y67_09785	COG0493	'glutamate synthase
C7Y67_09795	COG0398	Pfam SNARE associated Golgi protein
C7Y67_09800	COG4134	Bacterial extracellular solute-binding protein
C7Y67_09805	COG4135	transport system, permease component
C7Y67_09810	COG4136	ATPase activity
C7Y67_09815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7Y67_09830	COG3604	Transcriptional regulator
C7Y67_09835	COG1151	hydroxylamine reductase activity
C7Y67_09840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7Y67_09850	COG0564	pseudouridine synthase activity
C7Y67_09860	COG0733	neurotransmitter:sodium symporter activity
C7Y67_09870	COG0626	cystathionine gamma-synthase activity
C7Y67_09875	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7Y67_09880	COG5380	lipid catabolic process
C7Y67_09885	COG2818	Glycosylase
C7Y67_09900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7Y67_09905	COG1983	PspC domain protein
C7Y67_09915	COG1842	Phage shock protein A
C7Y67_09920	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7Y67_09930	COG4168	peptide transport system, permease
C7Y67_09935	COG4171	peptide transport system, permease
C7Y67_09945	COG4172	Belongs to the ABC transporter superfamily
C7Y67_09955	COG1227	inorganic diphosphatase activity
C7Y67_09970	COG0243	molybdopterin cofactor binding
C7Y67_09975	COG3005	denitrification pathway
C7Y67_09980	COG4459	periplasmic nitrate reductase
C7Y67_09985	COG0390	transport system, permease component
C7Y67_09995	COG2116	formate transmembrane transporter activity
C7Y67_10020	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C7Y67_10025	COG1435	thymidine kinase activity
C7Y67_10030	COG0215	cysteine-tRNA ligase activity
C7Y67_10035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7Y67_10040	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7Y67_10045	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7Y67_10055	COG3012	SEC-C Motif Domain Protein
C7Y67_10060	COG0140	phosphoribosyl-ATP diphosphatase activity
C7Y67_10060	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7Y67_10065	COG0107	imidazoleglycerol-phosphate synthase activity
C7Y67_10070	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7Y67_10075	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7Y67_10080	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C7Y67_10080	COG0131	Imidazoleglycerol-phosphate dehydratase
C7Y67_10085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7Y67_10090	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7Y67_10095	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7Y67_10110	COG1757	Na H antiporter
C7Y67_10120	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7Y67_10130	COG0482	sulfurtransferase activity
C7Y67_10135	COG2915	High frequency lysogenization protein hflD homolog
C7Y67_10140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7Y67_10165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C7Y67_10180	COG0300	oxidoreductase activity
C7Y67_10190	COG0501	Belongs to the peptidase M48B family
C7Y67_10200	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C7Y67_10210	COG0156	8-amino-7-oxononanoate synthase activity
C7Y67_10215	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7Y67_10220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7Y67_10225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7Y67_10240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7Y67_10245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7Y67_10250	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7Y67_10265	COG0686	Belongs to the AlaDH PNT family
C7Y67_10275	COG0583	DNA-binding transcription factor activity
C7Y67_10290	COG3568	Endonuclease Exonuclease Phosphatase
C7Y67_10320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7Y67_10325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7Y67_10340	COG0840	transmembrane signaling receptor activity
C7Y67_10395	COG5002	protein histidine kinase activity
C7Y67_10395	COG0784	Response regulator, receiver
C7Y67_10405	COG0754	glutathionylspermidine amidase activity
C7Y67_10415	COG3766	membrane
C7Y67_10425	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7Y67_10430	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C7Y67_10435	COG2885	chlorophyll binding
C7Y67_10440	COG0823	Involved in the tonB-independent uptake of proteins
C7Y67_10455	COG0811	peptide transport
C7Y67_10460	COG0824	Thioesterase
C7Y67_10470	COG4890	Cyd operon protein YbgT
C7Y67_10475	COG1294	oxidase, subunit
C7Y67_10480	COG1271	oxidase subunit
C7Y67_10485	COG2255	four-way junction helicase activity
C7Y67_10490	COG0632	four-way junction helicase activity
C7Y67_10495	COG0840	transmembrane signaling receptor activity
C7Y67_10500	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C7Y67_10505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7Y67_10510	COG1801	Protein of unknown function DUF72
C7Y67_10515	COG4106	trans-aconitate 2-methyltransferase activity
C7Y67_10520	COG0500	methyltransferase
C7Y67_10530	COG4067	protein conserved in archaea
C7Y67_10530	COG0189	ligase activity
C7Y67_10550	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C7Y67_10555	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C7Y67_10560	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
C7Y67_10565	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7Y67_10570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C7Y67_10575	COG0745	RESPONSE REGULATOR receiver
C7Y67_10580	COG3381	protein complex oligomerization
C7Y67_10585	COG1609	Transcriptional regulator
C7Y67_10590	COG3070	regulator of competence-specific genes
C7Y67_10610	COG0297	glycogen (starch) synthase activity
C7Y67_10615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7Y67_10620	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7Y67_10630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7Y67_10640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C7Y67_10645	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C7Y67_10650	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7Y67_10660	COG0542	response to heat
C7Y67_10665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C7Y67_10670	COG1278	Cold shock
C7Y67_10680	COG1187	pseudouridine synthase activity
C7Y67_10685	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C7Y67_10695	COG1199	ATP-dependent helicase activity
C7Y67_10700	COG0730	response to heat
C7Y67_10705	COG3923	Primosomal replication protein n
C7Y67_10715	COG0708	Exodeoxyribonuclease III
C7Y67_10730	COG4215	(ABC) transporter
C7Y67_10760	COG1882	Formate acetyltransferase
C7Y67_10770	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7Y67_10780	COG3013	Belongs to the UPF0304 family
C7Y67_10790	COG2766	serine protein kinase
C7Y67_10795	COG2718	Belongs to the UPF0229 family
C7Y67_10800	COG2719	SpoVR family
C7Y67_10805	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C7Y67_10815	COG1663	tetraacyldisaccharide 4'-kinase activity
C7Y67_10820	COG1132	(ABC) transporter
C7Y67_10825	COG0658	competence protein
C7Y67_10825	COG2333	competence protein COMEC
C7Y67_10835	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7Y67_10840	COG1136	(ABC) transporter
C7Y67_10845	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7Y67_10855	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7Y67_10870	COG1252	NADH dehydrogenase
C7Y67_10880	COG3150	esterase
C7Y67_10905	COG0537	adenosine 5'-monophosphoramidase activity
C7Y67_10935	COG0516	GMP reductase activity
C7Y67_10935	COG0517	IMP dehydrogenase activity
C7Y67_10945	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
C7Y67_10950	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C7Y67_10955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7Y67_10965	COG2199	diguanylate cyclase activity
C7Y67_10980	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C7Y67_10985	COG1946	Acyl-CoA thioesterase
C7Y67_10995	COG1522	sequence-specific DNA binding
C7Y67_11025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7Y67_11030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7Y67_11080	COG2855	membrane
C7Y67_11095	COG1441	menaquinone biosynthetic process
C7Y67_11100	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7Y67_11105	COG0596	Alpha beta hydrolase
C7Y67_11110	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C7Y67_11115	COG1169	isochorismate synthase
C7Y67_11120	COG0436	Aminotransferase
C7Y67_11125	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C7Y67_11130	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C7Y67_11145	COG1555	photosystem II stabilization
C7Y67_11150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7Y67_11155	COG0776	regulation of translation
C7Y67_11160	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7Y67_11165	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7Y67_11175	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7Y67_11185	COG2204	response regulator
C7Y67_11195	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C7Y67_11200	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C7Y67_11205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C7Y67_11210	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C7Y67_11230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7Y67_11235	COG0569	domain protein
C7Y67_11240	COG0513	Belongs to the DEAD box helicase family
C7Y67_11245	COG1253	flavin adenine dinucleotide binding
C7Y67_11280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7Y67_11285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7Y67_11305	COG1216	Glycosyl transferase, family 2
C7Y67_11310	COG2986	histidine ammonia-lyase
C7Y67_11335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7Y67_11340	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7Y67_11345	COG1028	Short-chain dehydrogenase reductase Sdr
C7Y67_11365	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7Y67_11370	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7Y67_11375	COG0583	DNA-binding transcription factor activity
C7Y67_11380	COG2951	lytic endotransglycosylase activity
C7Y67_11385	COG3100	YcgL domain-containing protein
C7Y67_11390	COG0850	regulation of cytokinetic process
C7Y67_11395	COG2894	cell division
C7Y67_11400	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C7Y67_11405	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C7Y67_11410	COG0318	PFAM AMP-dependent synthetase and ligase
C7Y67_11415	COG2267	carboxylic ester hydrolase activity
C7Y67_11430	COG1214	PFAM Peptidase M22, glycoprotease
C7Y67_11435	COG1199	ATP-dependent helicase activity
C7Y67_11440	COG0788	formyltetrahydrofolate deformylase activity
C7Y67_11445	COG3102	Protein conserved in bacteria
C7Y67_11455	COG0018	arginyl-trna synthetase
C7Y67_11475	COG1918	ferrous iron import across plasma membrane
C7Y67_11490	COG4977	sequence-specific DNA binding
C7Y67_11495	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C7Y67_11500	COG1121	(ABC) transporter
C7Y67_11505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7Y67_11515	COG0045	succinate-CoA ligase (ADP-forming) activity
C7Y67_11520	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7Y67_11525	COG0567	Dehydrogenase, E1 component
C7Y67_11530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7Y67_11535	COG1053	succinate dehydrogenase
C7Y67_11540	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C7Y67_11545	COG2009	succinate dehydrogenase
C7Y67_11555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7Y67_11565	COG0033	Phosphoglucomutase
C7Y67_11570	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C7Y67_11575	COG0596	Alpha beta hydrolase
C7Y67_11585	COG0716	FMN binding
C7Y67_11595	COG0735	belongs to the Fur family
C7Y67_11600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7Y67_11605	COG2190	(PTS) system
C7Y67_11605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7Y67_11605	COG1263	PTS System
C7Y67_11615	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7Y67_11620	COG1846	Transcriptional regulator
C7Y67_11620	COG1940	carbohydrate kinase activity
C7Y67_11625	COG4651	solute:proton antiporter activity
C7Y67_11625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7Y67_11630	COG0367	asparagine synthase
C7Y67_11635	COG0250	Participates in transcription elongation, termination and antitermination
C7Y67_11640	COG3104	oligopeptide transport
C7Y67_11645	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7Y67_11650	COG0563	adenylate kinase activity
C7Y67_11655	COG0326	Molecular chaperone. Has ATPase activity
C7Y67_11660	COG3710	Transcriptional regulator
C7Y67_11680	COG0622	Phosphoesterase
C7Y67_11710	COG1090	epimerase
C7Y67_11715	COG0300	oxidoreductase activity
C7Y67_11725	COG3118	belongs to the thioredoxin family
C7Y67_11730	COG0330	HflC and HflK could
C7Y67_11760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7Y67_11765	COG3115	cell septum assembly
C7Y67_11770	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
C7Y67_11775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7Y67_11785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7Y67_11790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7Y67_11795	COG2190	(PTS) system
C7Y67_11805	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7Y67_11810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7Y67_11820	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7Y67_11830	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7Y67_11840	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7Y67_11840	COG3951	Flagellar rod assembly protein muramidase FlgJ
C7Y67_11845	COG1706	bacterial-type flagellum-dependent cell motility
C7Y67_11850	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C7Y67_11855	COG4786	Flagellar basal body rod
C7Y67_11860	COG4787	bacterial-type flagellum-dependent cell motility
C7Y67_11870	COG1749	Flagellar hook protein flgE
C7Y67_11875	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7Y67_11880	COG1558	bacterial-type flagellum-dependent cell motility
C7Y67_11885	COG1815	bacterial-type flagellum-dependent cell motility
C7Y67_11890	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7Y67_11895	COG0835	chemotaxis
C7Y67_11895	COG0784	Response regulator, receiver
C7Y67_11955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7Y67_11960	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C7Y67_11975	COG2217	Heavy metal translocating P-type atpase
C7Y67_11975	COG2608	mercury ion transmembrane transporter activity
C7Y67_12015	COG2840	Smr protein MutS2
C7Y67_12020	COG1187	pseudouridine synthase activity
C7Y67_12030	COG0737	Belongs to the 5'-nucleotidase family
C7Y67_12035	COG2877	3-deoxy-8-phosphooctulonate synthase activity
C7Y67_12040	COG2912	Transglutaminase-like superfamily
C7Y67_12045	COG3094	Invasion gene expression up-regulator, SirB
C7Y67_12050	COG2890	protein-(glutamine-N5) methyltransferase activity
C7Y67_12055	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7Y67_12060	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7Y67_12065	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C7Y67_12070	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7Y67_12075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7Y67_12080	COG0193	aminoacyl-tRNA hydrolase activity
C7Y67_12085	COG0012	GTP binding
C7Y67_12200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7Y67_12210	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7Y67_12215	COG1702	phosphate starvation-inducible protein PhoH
C7Y67_12220	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7Y67_12225	COG4535	Mg2 and Co2 transporter CorC
C7Y67_12230	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C7Y67_12235	COG2888	peptidyl-tyrosine sulfation
C7Y67_12240	COG0495	leucyl-tRNA aminoacylation
C7Y67_12245	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
C7Y67_12250	COG1466	dna polymerase III delta subunit
C7Y67_12255	COG0799	negative regulation of ribosome biogenesis
C7Y67_12260	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7Y67_12265	COG0768	penicillin binding
C7Y67_12270	COG0772	Belongs to the SEDS family
C7Y67_12275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7Y67_12280	COG1686	Belongs to the peptidase S11 family
C7Y67_12285	COG2921	Belongs to the UPF0250 family
C7Y67_12290	COG0321	lipoyl(octanoyl) transferase activity
C7Y67_12295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7Y67_12300	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7Y67_12305	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7Y67_12320	COG0366	Alpha amylase catalytic
C7Y67_12325	COG1263	PTS System
C7Y67_12325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7Y67_12335	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C7Y67_12345	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7Y67_12350	COG2011	ABC-type metal ion transport system permease component
C7Y67_12355	COG1464	Belongs to the NlpA lipoprotein family
C7Y67_12360	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
C7Y67_12370	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7Y67_12370	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7Y67_12380	COG3706	GGDEF domain
C7Y67_12380	COG0745	RESPONSE REGULATOR receiver
C7Y67_12385	COG1611	Belongs to the LOG family
C7Y67_12390	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7Y67_12400	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
C7Y67_12405	COG2363	Small membrane protein
C7Y67_12415	COG0583	DNA-binding transcription factor activity
C7Y67_12420	COG0301	tRNA thio-modification
C7Y67_12420	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7Y67_12425	COG2885	chlorophyll binding
C7Y67_12430	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7Y67_12435	COG1722	exodeoxyribonuclease VII activity
C7Y67_12440	COG0142	geranyltranstransferase activity
C7Y67_12445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7Y67_12450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7Y67_12455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7Y67_12460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7Y67_12480	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7Y67_12480	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7Y67_12485	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7Y67_12490	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7Y67_12495	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C7Y67_12510	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C7Y67_12515	COG2252	PERMEase
C7Y67_12520	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7Y67_12545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7Y67_12545	COG0047	phosphoribosylformylglycinamidine synthase activity
C7Y67_12550	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C7Y67_12560	COG0590	tRNA wobble adenosine to inosine editing
C7Y67_12565	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C7Y67_12605	COG0484	heat shock protein binding
C7Y67_12610	COG0443	Heat shock 70 kDa protein
C7Y67_12620	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7Y67_12625	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7Y67_12635	COG0497	DNA recombination
C7Y67_12640	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7Y67_12645	COG2914	Belongs to the UPF0125 (RnfH) family
C7Y67_12650	COG2867	negative regulation of translational initiation
C7Y67_12655	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7Y67_12665	COG0582	viral genome integration into host DNA
C7Y67_12725	COG0732	type I restriction modification DNA specificity domain
C7Y67_12765	COG3706	GGDEF domain
C7Y67_12765	COG0745	RESPONSE REGULATOR receiver
C7Y67_12815	COG0583	DNA-binding transcription factor activity
C7Y67_12820	COG3153	acetyltransferase
C7Y67_12820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7Y67_12840	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7Y67_12845	COG2873	o-acetylhomoserine
C7Y67_12880	COG1115	amino acid carrier protein
C7Y67_12890	COG1584	GPR1 FUN34 yaaH family protein
C7Y67_12900	COG1757	Na H antiporter
C7Y67_12980	COG0582	viral genome integration into host DNA
C7Y67_12985	COG0519	Catalyzes the synthesis of GMP from XMP
C7Y67_12985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7Y67_12990	COG0517	IMP dehydrogenase activity
C7Y67_12990	COG0516	GMP reductase activity
C7Y67_12995	COG1570	exodeoxyribonuclease VII activity
C7Y67_13010	COG1160	GTP binding
C7Y67_13015	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7Y67_13020	COG2976	Protein conserved in bacteria
C7Y67_13025	COG0124	histidyl-tRNA synthetase
C7Y67_13030	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7Y67_13045	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7Y67_13050	COG0105	UTP biosynthetic process
C7Y67_13055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7Y67_13060	COG2975	iron-sulfur cluster assembly
C7Y67_13065	COG0633	Ferredoxin
C7Y67_13070	COG0443	Heat shock 70 kDa protein
C7Y67_13075	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C7Y67_13085	COG0822	iron-sulfur transferase activity
C7Y67_13090	COG1104	cysteine desulfurase activity
C7Y67_13095	COG1959	2 iron, 2 sulfur cluster binding
C7Y67_13105	COG0483	inositol monophosphate 1-phosphatase activity
C7Y67_13115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7Y67_13120	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7Y67_13125	COG1862	Preprotein translocase
C7Y67_13130	COG0343	queuine tRNA-ribosyltransferase activity
C7Y67_13135	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7Y67_13150	COG0517	IMP dehydrogenase activity
C7Y67_13160	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C7Y67_13170	COG0583	DNA-binding transcription factor activity
C7Y67_13175	COG0450	alkyl hydroperoxide reductase
C7Y67_13185	COG3142	Participates in the control of copper homeostasis
C7Y67_13195	COG0704	Plays a role in the regulation of phosphate uptake
C7Y67_13200	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7Y67_13205	COG0581	inorganic phosphate transmembrane transporter activity
C7Y67_13215	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C7Y67_13220	COG0248	Ppx GppA phosphatase
C7Y67_13230	COG5002	protein histidine kinase activity
C7Y67_13235	COG0745	RESPONSE REGULATOR receiver
C7Y67_13245	COG2974	May be involved in recombination
C7Y67_13255	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7Y67_13315	COG0542	response to heat
C7Y67_13325	COG0564	pseudouridine synthase activity
C7Y67_13330	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7Y67_13335	COG0741	lytic transglycosylase activity
C7Y67_13340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7Y67_13345	COG1605	Chorismate mutase
C7Y67_13345	COG0077	Prephenate dehydratase
C7Y67_13350	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C7Y67_13355	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
C7Y67_13365	COG0488	(ABC) transporter
C7Y67_13380	COG0739	heme binding
C7Y67_13385	COG1605	Chorismate mutase
C7Y67_13385	COG0287	Prephenate dehydrogenase
C7Y67_13390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C7Y67_13395	COG1472	Belongs to the glycosyl hydrolase 3 family
C7Y67_13400	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C7Y67_13405	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7Y67_13420	COG1966	Carbon starvation protein
C7Y67_13425	COG3275	phosphorelay sensor kinase activity
C7Y67_13430	COG3279	Response regulator of the LytR AlgR family
C7Y67_13435	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7Y67_13440	COG1047	Peptidyl-prolyl cis-trans
C7Y67_13445	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7Y67_13450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7Y67_13455	COG0196	riboflavin kinase activity
C7Y67_13460	COG0728	peptidoglycan biosynthetic process
C7Y67_13465	COG0268	Binds directly to 16S ribosomal RNA
C7Y67_13475	COG0640	Transcriptional regulator
C7Y67_13485	COG0583	DNA-binding transcription factor activity
C7Y67_13490	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7Y67_13500	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7Y67_13505	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7Y67_13510	COG0730	response to heat
C7Y67_13520	COG0494	nUDIX hydrolase
C7Y67_13530	COG3066	DNA modification
C7Y67_13540	COG0667	Aldo Keto reductase
C7Y67_13555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7Y67_13565	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7Y67_13570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7Y67_13580	COG0716	FMN binding
C7Y67_13590	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7Y67_13595	COG0513	Belongs to the DEAD box helicase family
C7Y67_13600	COG3022	response to hydroperoxide
C7Y67_13605	COG1115	amino acid carrier protein
C7Y67_13620	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7Y67_13630	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7Y67_13635	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
C7Y67_13640	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
C7Y67_13690	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7Y67_13695	COG0083	homoserine kinase activity
C7Y67_13710	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C7Y67_13725	COG0745	RESPONSE REGULATOR receiver
C7Y67_13735	COG2198	Histidine kinase
C7Y67_13735	COG5002	protein histidine kinase activity
C7Y67_13735	COG0784	Response regulator, receiver
C7Y67_13740	COG2203	Gaf domain
C7Y67_13740	COG3706	GGDEF domain
C7Y67_13740	COG4251	negative regulation of phosphorylation
C7Y67_13740	COG5001	Diguanylate cyclase
C7Y67_13745	COG1242	4 iron, 4 sulfur cluster binding
C7Y67_13750	COG0070	glutamate synthase
C7Y67_13750	COG0069	glutamate synthase activity
C7Y67_13750	COG0067	glutamate synthase
C7Y67_13760	COG0070	glutamate synthase
C7Y67_13760	COG0067	glutamate synthase
C7Y67_13760	COG0069	glutamate synthase activity
C7Y67_13765	COG0493	'glutamate synthase
C7Y67_13775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7Y67_13785	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7Y67_13790	COG2860	membrane
C7Y67_13795	COG0583	DNA-binding transcription factor activity
C7Y67_13800	COG0730	response to heat
C7Y67_13815	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7Y67_13820	COG0505	Belongs to the CarA family
C7Y67_13825	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7Y67_13830	COG0494	nUDIX hydrolase
C7Y67_13835	COG0653	protein targeting
C7Y67_13845	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C7Y67_13850	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7Y67_13855	COG0849	cell division
C7Y67_13860	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7Y67_13865	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7Y67_13870	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7Y67_13875	COG0772	Belongs to the SEDS family
C7Y67_13880	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7Y67_13885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7Y67_13890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7Y67_13895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7Y67_13900	COG0768	penicillin binding
C7Y67_13905	COG3116	cell division
C7Y67_13910	COG0275	rRNA processing
C7Y67_13925	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7Y67_13935	COG0792	nuclease activity
C7Y67_13940	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C7Y67_13945	COG2823	Periplasmic or secreted lipoprotein
C7Y67_13950	COG2969	positive regulation of protein catabolic process
C7Y67_13955	COG0625	glutathione transferase activity
C7Y67_13960	COG2857	Cytochrome c1
C7Y67_13965	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7Y67_13970	COG0723	plastoquinol--plastocyanin reductase activity
C7Y67_13975	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7Y67_13980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7Y67_13990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C7Y67_14000	COG3105	Protein conserved in bacteria
C7Y67_14010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7Y67_14020	COG0187	DNA topoisomerase II activity
C7Y67_14025	COG3150	esterase
C7Y67_14035	COG3151	Protein conserved in bacteria
C7Y67_14040	COG0494	nUDIX hydrolase
C7Y67_14045	COG1538	Outer membrane efflux protein
C7Y67_14050	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7Y67_14050	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C7Y67_14055	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C7Y67_14070	COG3025	triphosphatase activity
C7Y67_14075	COG1392	Phosphate transport regulator
C7Y67_14080	COG0306	phosphate transporter
C7Y67_14085	COG4991	sh3 domain protein
C7Y67_14095	COG3267	Type II secretory pathway component ExeA
C7Y67_14095	COG3409	Peptidoglycan-binding domain 1 protein
C7Y67_14100	COG0617	tRNA 3'-terminal CCA addition
C7Y67_14105	COG1968	undecaprenyl-diphosphatase activity
C7Y67_14110	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7Y67_14115	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7Y67_14120	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7Y67_14125	COG0596	Alpha beta hydrolase
C7Y67_14130	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7Y67_14135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7Y67_14140	COG1610	YqeY-like protein
C7Y67_14145	COG0358	DNA primase activity
C7Y67_14150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7Y67_14195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7Y67_14205	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7Y67_14220	COG3550	peptidyl-serine autophosphorylation
C7Y67_14230	COG5001	Diguanylate cyclase
C7Y67_14230	COG3300	MHYT domain
C7Y67_14280	COG0732	type I restriction modification DNA specificity domain
C7Y67_14305	COG2264	protein methyltransferase activity
C7Y67_14315	COG1162	GTPase activity
C7Y67_14325	COG3706	GGDEF domain
C7Y67_14360	COG1464	Belongs to the NlpA lipoprotein family
C7Y67_14370	COG2207	Transcriptional regulator
C7Y67_14405	COG2213	PTS system mannitol-specific
C7Y67_14405	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7Y67_14410	COG0246	Mannitol dehydrogenase
C7Y67_14415	COG3722	fumarate hydratase activity
C7Y67_14430	COG1461	Dihydroxyacetone kinase
C7Y67_14435	COG2376	Dihydroxyacetone kinase
C7Y67_14445	COG5002	protein histidine kinase activity
C7Y67_14460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7Y67_14465	COG1349	DNA-binding transcription factor activity
C7Y67_14475	COG0469	pyruvate kinase activity
C7Y67_14485	COG3706	GGDEF domain
C7Y67_14490	COG0440	acetolactate synthase activity
C7Y67_14495	COG0028	Belongs to the TPP enzyme family
C7Y67_14500	COG1022	Amp-dependent synthetase and ligase
C7Y67_14505	COG0583	DNA-binding transcription factor activity
C7Y67_14525	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7Y67_14530	COG0473	3-isopropylmalate dehydrogenase activity
C7Y67_14535	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7Y67_14540	COG0066	3-isopropylmalate dehydratase activity
C7Y67_14550	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C7Y67_14555	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C7Y67_14560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7Y67_14565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C7Y67_14570	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7Y67_14575	COG2967	ApaG domain
C7Y67_14580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7Y67_14595	COG2966	Psort location CytoplasmicMembrane, score
C7Y67_14600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7Y67_14610	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7Y67_14615	COG0142	geranyltranstransferase activity
C7Y67_14625	COG0039	L-malate dehydrogenase activity
C7Y67_14660	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C7Y67_14665	COG1178	ABC-type Fe3 transport system permease component
C7Y67_14670	COG4143	(ABC) transporter
C7Y67_14675	COG0163	prenyltransferase activity
C7Y67_14680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7Y67_14690	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C7Y67_14695	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C7Y67_14705	COG2105	PFAM AIG2 family protein
C7Y67_14710	COG2911	Protein conserved in bacteria
C7Y67_14715	COG0729	surface antigen
C7Y67_14720	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7Y67_14730	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C7Y67_14745	COG4181	ATPase activity
C7Y67_14765	COG0529	Catalyzes the synthesis of activated sulfate
C7Y67_14770	COG3273	potassium ion transport
C7Y67_14770	COG0471	metal ion transport
C7Y67_14780	COG2895	sulfate adenylyltransferase (ATP) activity
C7Y67_14785	COG0175	sulfate reduction
C7Y67_14790	COG1648	precorrin-2 dehydrogenase activity
C7Y67_14790	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7Y67_14795	COG0737	Belongs to the 5'-nucleotidase family
C7Y67_14805	COG0513	Belongs to the DEAD box helicase family
C7Y67_14810	COG2153	protein acetylation
C7Y67_14820	COG0545	Peptidyl-prolyl cis-trans isomerase
C7Y67_14830	COG0203	ribosomal protein L17
C7Y67_14835	COG0202	RNA polymerase activity
C7Y67_14845	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7Y67_14850	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7Y67_14860	COG0201	protein transport
C7Y67_14865	COG0200	Binds to the 23S rRNA
C7Y67_14870	COG1841	ribosomal large subunit assembly
C7Y67_14885	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7Y67_14890	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7Y67_14895	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7Y67_14900	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7Y67_14905	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7Y67_14910	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7Y67_14915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7Y67_14920	COG0255	Belongs to the universal ribosomal protein uL29 family
C7Y67_14930	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7Y67_14935	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7Y67_14940	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7Y67_14945	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7Y67_14955	COG0088	Forms part of the polypeptide exit tunnel
C7Y67_14960	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7Y67_14970	COG0254	rRNA binding
C7Y67_14980	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7Y67_14985	COG1609	Transcriptional regulator
C7Y67_14995	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7Y67_15000	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7Y67_15005	COG1575	Belongs to the MenA family. Type 1 subfamily
C7Y67_15010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C7Y67_15015	COG3074	FtsZ-dependent cytokinesis
C7Y67_15025	COG1494	fructose-1,6-bisphosphatase
C7Y67_15050	COG0149	triose-phosphate isomerase activity
C7Y67_15055	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C7Y67_15070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7Y67_15075	COG1215	transferase activity, transferring glycosyl groups
C7Y67_15085	COG0438	transferase activity, transferring glycosyl groups
C7Y67_15090	COG1216	Glycosyl transferase, family 2
C7Y67_15090	COG0463	Glycosyl transferase, family 2
C7Y67_15110	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C7Y67_15140	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7Y67_15150	COG1560	Kdo2-lipid A biosynthetic process
C7Y67_15160	COG0859	PFAM glycosyl transferase family 9
C7Y67_15165	COG1519	Transferase
C7Y67_15180	COG0367	asparagine synthase
C7Y67_15195	COG0728	peptidoglycan biosynthetic process
C7Y67_15205	COG1083	cytidylyl-transferase
C7Y67_15210	COG3642	lipopolysaccharide core region biosynthetic process
C7Y67_15215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7Y67_15220	COG0859	PFAM glycosyl transferase family 9
C7Y67_15225	COG0463	Glycosyl transferase, family 2
C7Y67_15240	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7Y67_15245	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7Y67_15255	COG2194	sulfuric ester hydrolase activity
C7Y67_15265	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7Y67_15270	COG2003	Belongs to the UPF0758 family
C7Y67_15285	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7Y67_15290	COG1309	transcriptional regulator
C7Y67_15295	COG1560	Kdo2-lipid A biosynthetic process
C7Y67_15300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7Y67_15305	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7Y67_15315	COG1561	YicC-like family, N-terminal region
C7Y67_15390	COG1061	Type III restriction enzyme res subunit
C7Y67_15450	COG4608	Belongs to the ABC transporter superfamily
C7Y67_15455	COG0444	Belongs to the ABC transporter superfamily
C7Y67_15460	COG0747	negative chemotaxis
C7Y67_15465	COG4239	(ABC) transporter, permease
C7Y67_15470	COG4174	ABC transporter (Permease)
C7Y67_15495	COG0811	peptide transport
C7Y67_15500	COG0848	biopolymer transport protein
C7Y67_15515	COG0194	GDP metabolic process
C7Y67_15520	COG1758	RNA polymerase activity
C7Y67_15525	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7Y67_15530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7Y67_15535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7Y67_15545	COG2233	PERMEase
C7Y67_15550	COG2205	protein histidine kinase activity
C7Y67_15555	COG0745	RESPONSE REGULATOR receiver
C7Y67_15565	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7Y67_15575	COG2183	response to ionizing radiation
C7Y67_15585	COG0596	Alpha beta hydrolase
C7Y67_15590	COG1040	competence protein
C7Y67_15595	COG0316	Belongs to the HesB IscA family
C7Y67_15595	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7Y67_15600	COG0494	nUDIX hydrolase
C7Y67_15605	COG1218	3'(2'),5'-bisphosphate nucleotidase
C7Y67_15615	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C7Y67_15620	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C7Y67_15625	COG3156	type II secretion system protein K
C7Y67_15630	COG4795	General secretion pathway protein
C7Y67_15635	COG2165	general secretion pathway protein
C7Y67_15640	COG2165	general secretion pathway protein
C7Y67_15645	COG2165	general secretion pathway protein
C7Y67_15650	COG1459	type II secretion system
C7Y67_15655	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7Y67_15665	COG3031	protein transport across the cell outer membrane
C7Y67_15670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7Y67_15675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7Y67_15680	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C7Y67_15690	COG0456	acetyltransferase
C7Y67_15695	COG1490	D-aminoacyl-tRNA deacylase activity
C7Y67_15700	COG1295	ribonuclease BN
C7Y67_15720	COG0174	glutamine synthetase
C7Y67_15730	COG3852	Histidine kinase
C7Y67_15735	COG2204	response regulator
C7Y67_15745	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C7Y67_15750	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7Y67_15785	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7Y67_15795	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7Y67_15795	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7Y67_15820	COG0084	hydrolase, TatD family'
C7Y67_15830	COG0805	protein transport
C7Y67_15840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7Y67_15845	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7Y67_15850	COG3165	ubiquinone biosynthetic process from chorismate
C7Y67_15855	COG2226	methyltransferase
C7Y67_15860	COG1322	Protein conserved in bacteria
C7Y67_15875	COG0628	permease
C7Y67_15905	COG1597	lipid kinase activity
C7Y67_15925	COG2823	Periplasmic or secreted lipoprotein
C7Y67_15935	COG2081	HI0933 family
C7Y67_15945	COG1528	Iron-storage protein
C7Y67_15950	COG0589	response to stress
C7Y67_15955	COG0697	spore germination
C7Y67_15965	COG0742	ribosomal rna small subunit methyltransferase
C7Y67_15970	COG5002	protein histidine kinase activity
C7Y67_15970	COG5001	Diguanylate cyclase
C7Y67_15975	COG1522	sequence-specific DNA binding
C7Y67_15980	COG0339	signal peptide processing
C7Y67_15990	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C7Y67_15995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7Y67_16000	COG0583	DNA-binding transcription factor activity
C7Y67_16005	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C7Y67_16010	COG0800	Aldolase
C7Y67_16015	COG2610	gluconate transmembrane transporter activity
C7Y67_16020	COG3265	gluconokinase activity
C7Y67_16025	COG0129	dihydroxy-acid dehydratase activity
C7Y67_16030	COG2076	Multidrug Resistance protein
C7Y67_16040	COG0583	DNA-binding transcription factor activity
C7Y67_16045	COG1609	Transcriptional regulator
C7Y67_16085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7Y67_16095	COG0747	negative chemotaxis
C7Y67_16100	COG4172	Belongs to the ABC transporter superfamily
C7Y67_16165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7Y67_16170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7Y67_16180	COG2960	long-chain fatty acid transporting porin activity
C7Y67_16185	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7Y67_16190	COG0583	DNA-binding transcription factor activity
C7Y67_16240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7Y67_16245	COG1739	Uncharacterized protein family UPF0029
C7Y67_16250	COG1024	Enoyl-CoA hydratase
C7Y67_16250	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7Y67_16255	COG0183	Belongs to the thiolase family
C7Y67_16260	COG0604	alcohol dehydrogenase
C7Y67_16275	COG0425	Belongs to the sulfur carrier protein TusA family
C7Y67_16285	COG2119	membrane
C7Y67_16290	COG0752	glycyl-tRNA synthetase alpha subunit
C7Y67_16295	COG0751	glycine-tRNA ligase activity
C7Y67_16300	COG0366	Alpha amylase catalytic
C7Y67_16305	COG3977	Valine--pyruvate aminotransferase
C7Y67_16310	COG0071	Belongs to the small heat shock protein (HSP20) family
C7Y67_16330	COG0187	DNA topoisomerase II activity
C7Y67_16335	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C7Y67_16340	COG0592	DNA-directed DNA polymerase activity
C7Y67_16345	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7Y67_16365	COG1126	abc transporter atp-binding protein
C7Y67_16375	COG0594	ribonuclease P activity
C7Y67_16380	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7Y67_16385	COG0706	membrane insertase activity
C7Y67_16390	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7Y67_16395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7Y67_16400	COG0445	tRNA wobble uridine modification
C7Y67_16405	COG0357	Ribosomal RNA small subunit methyltransferase G
C7Y67_16410	COG1192	Involved in chromosome partitioning
C7Y67_16415	COG1475	DNA binding
C7Y67_16420	COG3312	ion transport
C7Y67_16425	COG0356	it plays a direct role in the translocation of protons across the membrane
C7Y67_16440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7Y67_16445	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7Y67_16450	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7Y67_16455	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7Y67_16460	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7Y67_16465	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7Y67_16470	COG0765	amino acid transport
C7Y67_16475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7Y67_16480	COG2814	Major facilitator Superfamily
C7Y67_16485	COG0583	DNA-binding transcription factor activity
C7Y67_16495	COG0129	dihydroxy-acid dehydratase activity
C7Y67_16500	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7Y67_16505	COG3978	acetolactate synthase activity
C7Y67_16515	COG0606	chelatase, subunit chli
C7Y67_16525	COG0204	Acyl-transferase
C7Y67_16530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7Y67_16535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7Y67_16545	COG3084	Protein conserved in bacteria
C7Y67_16555	COG4326	sporulation control protein
C7Y67_16560	COG1272	protein, Hemolysin III
C7Y67_16570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7Y67_16575	COG0569	domain protein
C7Y67_16580	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7Y67_16580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7Y67_16585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7Y67_16590	COG0242	peptide deformylase activity
C7Y67_16600	COG0758	DNA mediated transformation
C7Y67_16605	COG2922	Belongs to the Smg family
C7Y67_16610	COG0551	DNA topoisomerase type I activity
C7Y67_16615	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7Y67_16620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7Y67_16625	COG0009	L-threonylcarbamoyladenylate synthase
C7Y67_16630	COG0408	coproporphyrinogen oxidase activity
C7Y67_16635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7Y67_16645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7Y67_16710	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7Y67_16715	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7Y67_16720	COG0352	thiamine-phosphate diphosphorylase activity
C7Y67_16725	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7Y67_16730	COG2104	thiamine diphosphate biosynthetic process
C7Y67_16735	COG2022	thiamine diphosphate biosynthetic process
C7Y67_16745	COG0006	proline dipeptidase activity
C7Y67_16745	COG0006	proline dipeptidase activity
C7Y67_16775	COG3220	belongs to the UPF0276 family
C7Y67_16785	COG0210	DNA helicase
C7Y67_16795	COG0405	Gamma-glutamyltransferase
C7Y67_16800	COG1280	lysine exporter protein (LysE YggA)
C7Y67_16810	COG2962	Rard protein
C7Y67_16815	COG0514	ATP-dependent DNA helicase (RecQ)
C7Y67_16830	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7Y67_16835	COG0248	Ppx GppA phosphatase
C7Y67_16840	COG0513	Belongs to the DEAD box helicase family
C7Y67_16845	COG3118	belongs to the thioredoxin family
C7Y67_16850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C7Y67_16865	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7Y67_16870	COG0633	Ferredoxin
C7Y67_16925	COG3071	HemY protein
C7Y67_16930	COG2959	enzyme of heme biosynthesis
C7Y67_16935	COG1587	Uroporphyrinogen-III synthase
C7Y67_16940	COG0181	hydroxymethylbilane synthase activity
C7Y67_16945	COG3072	Adenylate cyclase
C7Y67_16950	COG1965	Belongs to the frataxin family
C7Y67_16960	COG0019	diaminopimelate decarboxylase activity
C7Y67_16965	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7Y67_16975	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C7Y67_16980	COG1011	Hydrolase
C7Y67_16985	COG2199	diguanylate cyclase activity
C7Y67_16985	COG2200	EAL domain
C7Y67_16985	COG3287	FIST C domain
C7Y67_17005	COG0561	phosphatase activity
C7Y67_17015	COG2267	carboxylic ester hydrolase activity
C7Y67_17020	COG1280	lysine exporter protein (LysE YggA)
C7Y67_17025	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7Y67_17030	COG0640	Transcriptional regulator
C7Y67_17035	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7Y67_17095	COG2095	MarC family integral membrane protein
C7Y67_17100	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7Y67_17115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7Y67_17150	COG0742	ribosomal rna small subunit methyltransferase
C7Y67_17155	COG0552	protein localization to endoplasmic reticulum
C7Y67_17160	COG2884	Cell division ATP-binding protein ftsE
C7Y67_17165	COG2177	Part of the ABC transporter FtsEX involved in
C7Y67_17180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7Y67_17185	COG0705	Rhomboid family
C7Y67_17190	COG1580	Controls the rotational direction of flagella during chemotaxis
C7Y67_17195	COG3161	chorismate lyase activity
C7Y67_17200	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C7Y67_17205	COG2937	Belongs to the GPAT DAPAT family
C7Y67_17220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7Y67_17225	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C7Y67_17230	COG0534	Mate efflux family protein
C7Y67_17235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7Y67_17250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7Y67_17255	COG4206	TonB-dependent receptor
C7Y67_17265	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7Y67_17315	COG4974	Belongs to the 'phage' integrase family
C7Y67_17335	COG2205	protein histidine kinase activity
C7Y67_17335	COG0784	Response regulator, receiver
C7Y67_17355	COG3300	MHYT domain
C7Y67_17355	COG5001	Diguanylate cyclase
C7Y67_17365	COG0330	HflC and HflK could
C7Y67_17380	COG4175	Glycine betaine
C7Y67_17380	COG0517	IMP dehydrogenase activity
C7Y67_17385	COG4176	ABC-type proline glycine betaine transport system permease component
C7Y67_17400	COG1012	belongs to the aldehyde dehydrogenase family
C7Y67_17405	COG1309	transcriptional regulator
C7Y67_17410	COG3706	GGDEF domain
C7Y67_17420	COG1028	Short-chain dehydrogenase reductase Sdr
C7Y67_17435	COG1024	Enoyl-CoA hydratase
C7Y67_17440	COG1960	acyl-CoA dehydrogenase activity
C7Y67_17450	COG0183	Belongs to the thiolase family
C7Y67_17460	COG1960	acyl-CoA dehydrogenase activity
C7Y67_17465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7Y67_17485	COG2205	protein histidine kinase activity
C7Y67_17485	COG3437	response regulator, receiver
C7Y67_17485	COG3850	Histidine kinase
C7Y67_17485	COG4999	Histidine kinase
C7Y67_17500	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C7Y67_17500	COG3264	Mechanosensitive ion channel
C7Y67_17510	COG0110	maltose O-acetyltransferase activity
C7Y67_17515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7Y67_17520	COG1271	oxidase subunit
C7Y67_17525	COG1294	oxidase, subunit
C7Y67_17535	COG0384	phenazine biosynthesis protein PhzF
C7Y67_17540	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7Y67_17545	COG0789	Transcriptional regulator
C7Y67_17555	COG3474	cytochrome
C7Y67_17560	COG1013	pyruvate-flavodoxin oxidoreductase activity
C7Y67_17565	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C7Y67_17565	COG0674	pyruvate-flavodoxin oxidoreductase activity
C7Y67_17635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7Y67_17640	COG0516	GMP reductase activity
C7Y67_17645	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C7Y67_17645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7Y67_17660	COG4989	oxidoreductase activity
C7Y67_17675	COG0038	chloride channel
C7Y67_17685	COG1914	H( )-stimulated, divalent metal cation uptake system
C7Y67_17690	COG0302	gtp cyclohydrolase
C7Y67_17700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7Y67_17720	COG2897	thiosulfate sulfurtransferase activity
C7Y67_17750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7Y67_17755	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7Y67_17760	COG0840	transmembrane signaling receptor activity
C7Y67_17770	COG2814	Major facilitator Superfamily
C7Y67_17775	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C7Y67_17790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7Y67_17800	COG0840	transmembrane signaling receptor activity
C7Y67_17820	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7Y67_17835	COG2197	response regulator
C7Y67_17840	COG3850	Histidine kinase
C7Y67_17845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7Y67_17855	COG0243	molybdopterin cofactor binding
C7Y67_17865	COG3005	denitrification pathway
C7Y67_17885	COG0183	Belongs to the thiolase family
C7Y67_17905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7Y67_17910	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7Y67_17940	COG1522	sequence-specific DNA binding
C7Y67_17960	COG1566	PFAM secretion protein HlyD family protein
C7Y67_17970	COG2205	protein histidine kinase activity
C7Y67_17970	COG0784	Response regulator, receiver
C7Y67_17975	COG1879	ABC-type sugar transport system periplasmic component
C7Y67_17980	COG2827	Endonuclease containing a URI domain
C7Y67_17985	COG3132	Protein of unknown function, DUF480
C7Y67_18000	COG2926	Belongs to the UPF0265 family
C7Y67_18010	COG0534	Mate efflux family protein
C7Y67_18015	COG0673	inositol 2-dehydrogenase activity
C7Y67_18055	COG0531	amino acid
C7Y67_18070	COG2205	protein histidine kinase activity
C7Y67_18075	COG0745	RESPONSE REGULATOR receiver
C7Y67_18100	COG1566	PFAM secretion protein HlyD family protein
C7Y67_18105	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7Y67_18110	COG2239	Acts as a magnesium transporter
C7Y67_18120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7Y67_18125	COG0402	S-adenosylhomocysteine deaminase activity
C7Y67_18135	COG1418	mRNA catabolic process
C7Y67_18150	COG2814	Major facilitator Superfamily
C7Y67_18160	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7Y67_18180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7Y67_18200	COG4221	oxidoreductase activity
C7Y67_18205	COG0745	RESPONSE REGULATOR receiver
C7Y67_18210	COG2205	protein histidine kinase activity
C7Y67_18220	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7Y67_18225	COG2194	sulfuric ester hydrolase activity
C7Y67_18230	COG0673	inositol 2-dehydrogenase activity
C7Y67_18255	COG1846	Transcriptional regulator
C7Y67_18265	COG4667	esterase of the alpha-beta hydrolase superfamily
C7Y67_18270	COG1741	Belongs to the pirin family
C7Y67_18275	COG1278	Cold shock
C7Y67_18295	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C7Y67_18300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7Y67_18300	COG0678	peroxiredoxin activity
C7Y67_18320	COG1686	Belongs to the peptidase S11 family
C7Y67_18335	COG0625	glutathione transferase activity
C7Y67_18345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C7Y67_18370	COG1028	Short-chain dehydrogenase reductase Sdr
C7Y67_18385	COG3746	phosphate-selective porin O and P
C7Y67_18405	COG3833	ABC-type maltose transport systems, permease component
C7Y67_18410	COG1175	transmembrane transport
C7Y67_18420	COG3842	ATPase activity
C7Y67_18485	COG1309	transcriptional regulator
C7Y67_18490	COG2130	NADP-dependent
C7Y67_18500	COG0753	catalase activity
C7Y67_18505	COG2084	Dehydrogenase
C7Y67_18510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7Y67_18515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7Y67_18525	COG2207	Transcriptional regulator
C7Y67_18530	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7Y67_18530	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7Y67_18530	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7Y67_18545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7Y67_18550	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
C7Y67_18560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7Y67_18565	COG0569	domain protein
C7Y67_18575	COG5002	protein histidine kinase activity
C7Y67_18580	COG1132	(ABC) transporter
C7Y67_18585	COG4774	siderophore transport
C7Y67_18590	COG1120	ATPase activity
C7Y67_18595	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7Y67_18645	COG2197	response regulator
C7Y67_18655	COG0840	transmembrane signaling receptor activity
C7Y67_18665	COG0714	Associated with various cellular activities
C7Y67_18685	COG2304	oxidoreductase activity
C7Y67_18700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7Y67_18705	COG0581	inorganic phosphate transmembrane transporter activity
C7Y67_18710	COG0573	inorganic phosphate transmembrane transporter activity
C7Y67_18715	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7Y67_18740	COG4771	TonB-dependent receptor
C7Y67_18745	COG1770	oligopeptidase
C7Y67_18750	COG0513	Belongs to the DEAD box helicase family
C7Y67_18760	COG1376	ErfK ybiS ycfS ynhG family protein
C7Y67_18760	COG1388	LysM domain
C7Y67_18765	COG0415	Belongs to the DNA photolyase family
C7Y67_18770	COG0789	Transcriptional regulator
C7Y67_18775	COG3272	Protein of unknown function (DUF1722)
C7Y67_18785	COG0813	purine-nucleoside phosphorylase activity
C7Y67_18800	COG3706	GGDEF domain
C7Y67_18810	COG1566	PFAM secretion protein HlyD family protein
C7Y67_18815	COG4720	Psort location CytoplasmicMembrane, score
C7Y67_18820	COG1122	ATPase activity
C7Y67_18835	COG0348	domain, Protein
C7Y67_18840	COG0437	4 iron, 4 sulfur cluster binding
C7Y67_18845	COG1247	-acetyltransferase
C7Y67_18875	COG1067	ATP-dependent peptidase activity
C7Y67_18885	COG4172	Belongs to the ABC transporter superfamily
C7Y67_18890	COG1505	serine-type exopeptidase activity
C7Y67_18895	COG0583	DNA-binding transcription factor activity
C7Y67_18900	COG1620	l-lactate permease
C7Y67_18905	COG1304	FMN binding
C7Y67_18915	COG0668	transmembrane transport
C7Y67_18955	COG1063	alcohol dehydrogenase
C7Y67_18960	COG0156	8-amino-7-oxononanoate synthase activity
C7Y67_18970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7Y67_18990	COG0745	RESPONSE REGULATOR receiver
C7Y67_19025	COG0346	lactoylglutathione lyase activity
C7Y67_19045	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7Y67_19085	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7Y67_19100	COG2204	response regulator
C7Y67_19125	COG1987	bacterial-type flagellum assembly
C7Y67_19135	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7Y67_19150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7Y67_19160	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C7Y67_19165	COG1516	flagellar protein fliS
C7Y67_19180	COG1580	Controls the rotational direction of flagella during chemotaxis
C7Y67_19185	COG1191	sigma factor activity
C7Y67_19190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7Y67_19195	COG1360	Flagellar Motor Protein
C7Y67_19250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7Y67_19255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7Y67_19265	COG0454	-acetyltransferase
C7Y67_19275	COG2814	Major facilitator Superfamily
C7Y67_19320	COG0628	permease
C7Y67_19325	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C7Y67_19335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7Y67_19345	COG4628	conserved protein (DUF2132)
C7Y67_19350	COG0583	DNA-binding transcription factor activity
C7Y67_19375	COG1686	Belongs to the peptidase S11 family
C7Y67_19395	COG3397	chitin binding
C7Y67_19400	COG4667	esterase of the alpha-beta hydrolase superfamily
C7Y67_19405	COG2095	MarC family integral membrane protein
C7Y67_19425	COG3206	protein involved in exopolysaccharide biosynthesis
C7Y67_19425	COG0489	protein tyrosine kinase activity
C7Y67_19440	COG0583	DNA-binding transcription factor activity
C7Y67_19470	COG1301	dicarboxylic acid transport
C7Y67_19475	COG3339	Conserved Protein
C7Y67_19485	COG0700	Nucleoside recognition
C7Y67_19490	COG3366	ferrous iron transmembrane transporter activity
C7Y67_19505	COG0366	Alpha amylase catalytic
C7Y67_19510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7Y67_19515	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7Y67_19520	COG1640	4-alpha-glucanotransferase
C7Y67_19525	COG0058	SHG alpha-glucan phosphorylase activity
C7Y67_19540	COG2909	trisaccharide binding
C7Y67_19555	COG1999	signal sequence binding
C7Y67_19565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7Y67_19565	COG1263	PTS System
C7Y67_19570	COG1162	GTPase activity
C7Y67_19575	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C7Y67_19585	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C7Y67_19595	COG0531	amino acid
C7Y67_19600	COG1982	Orn Lys Arg decarboxylase major
C7Y67_19620	COG2356	endonuclease I
C7Y67_19645	COG4580	involved in the transport of maltose and maltodextrins
C7Y67_19660	COG2814	Major facilitator Superfamily
C7Y67_19670	COG0739	heme binding
C7Y67_19680	COG0612	Peptidase, M16
C7Y67_19685	COG0840	transmembrane signaling receptor activity
C7Y67_19690	COG1120	ATPase activity
C7Y67_19695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7Y67_19700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7Y67_19705	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C7Y67_19710	COG4772	TonB-dependent receptor
C7Y67_19735	COG4264	IucA IucC family
C7Y67_19740	COG0019	diaminopimelate decarboxylase activity
C7Y67_19745	COG1653	transport
C7Y67_19755	COG0745	RESPONSE REGULATOR receiver
C7Y67_19780	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7Y67_19785	COG1129	ABC transporter
C7Y67_19790	COG1879	ABC-type sugar transport system periplasmic component
C7Y67_19795	COG1069	ribulokinase activity
C7Y67_19805	COG2160	L-arabinose isomerase activity
C7Y67_19830	COG1764	response to oxidative stress
C7Y67_19835	COG1846	Transcriptional regulator
C7Y67_19840	COG0450	alkyl hydroperoxide reductase
C7Y67_19845	COG3634	alkyl hydroperoxide reductase activity
C7Y67_19880	COG1595	DNA-templated transcription, initiation
C7Y67_19895	COG0840	transmembrane signaling receptor activity
C7Y67_19900	COG0583	DNA-binding transcription factor activity
C7Y67_19905	COG1486	melibiose metabolic process
C7Y67_19920	COG2258	MOSC domain
C7Y67_19925	COG0513	Belongs to the DEAD box helicase family
C7Y67_19935	COG2186	Transcriptional regulator
C7Y67_19945	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C7Y67_19955	COG0246	Mannitol dehydrogenase
C7Y67_19960	COG1904	glucuronate isomerase
C7Y67_19970	COG0800	Aldolase
C7Y67_19995	COG2207	Transcriptional regulator
C7Y67_20005	COG1132	(ABC) transporter
C7Y67_20050	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7Y67_20080	COG0259	pyridoxamine-phosphate oxidase activity
C7Y67_20130	COG4166	transmembrane transport
C7Y67_20150	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C7Y67_20155	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7Y67_20155	COG1263	PTS System
C7Y67_20160	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C7Y67_20165	COG3340	Belongs to the peptidase S51 family
C7Y67_20185	COG1444	tRNA N-acetyltransferase activity
C7Y67_20215	COG4608	Belongs to the ABC transporter superfamily
C7Y67_20220	COG0444	Belongs to the ABC transporter superfamily
C7Y67_20230	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7Y67_20230	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C7Y67_20255	COG0217	transcriptional regulatory protein
C7Y67_20260	COG0772	Belongs to the SEDS family
C7Y67_20275	COG1136	(ABC) transporter
C7Y67_20295	COG3275	phosphorelay sensor kinase activity
C7Y67_20300	COG3279	Response regulator of the LytR AlgR family
C7Y67_20310	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7Y67_20345	COG0786	glutamate:sodium symporter activity
C7Y67_20355	COG1131	(ABC) transporter
C7Y67_20360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7Y67_20365	COG0786	glutamate:sodium symporter activity
C7Y67_20380	COG0363	glucosamine-6-phosphate deaminase activity
C7Y67_20400	COG1741	Belongs to the pirin family
C7Y67_20405	COG2259	Doxx family
C7Y67_20420	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C7Y67_20425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7Y67_20435	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C7Y67_20475	COG3123	guanosine phosphorylase activity
C7Y67_20485	COG5001	Diguanylate cyclase
C7Y67_20495	COG0534	Mate efflux family protein
C7Y67_20500	COG0564	pseudouridine synthase activity
C7Y67_20515	COG0583	DNA-binding transcription factor activity
C7Y67_20520	COG0561	phosphatase activity
C7Y67_20530	COG2199	diguanylate cyclase activity
C7Y67_20545	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C7Y67_20550	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C7Y67_20555	COG0583	DNA-binding transcription factor activity
C7Y67_20570	COG1414	Transcriptional regulator
C7Y67_20575	COG1028	Short-chain dehydrogenase reductase Sdr
C7Y67_20585	COG1917	Cupin 2, conserved barrel domain protein
C7Y67_20600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7Y67_20605	COG0800	Aldolase
C7Y67_20625	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7Y67_20630	COG0823	Involved in the tonB-independent uptake of proteins
C7Y67_20635	COG2375	cellular response to nickel ion
C7Y67_20665	COG1357	PFAM Pentapeptide repeats (8 copies)
C7Y67_20670	COG3047	cAMP biosynthetic process
C7Y67_20700	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C7Y67_20700	COG3408	Glycogen debranching enzyme
C7Y67_20705	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C7Y67_20715	COG0583	DNA-binding transcription factor activity
C7Y67_20725	COG0583	DNA-binding transcription factor activity
C7Y67_20740	COG0546	phosphoglycolate phosphatase activity
C7Y67_20765	COG3835	regulator
C7Y67_20770	COG2610	gluconate transmembrane transporter activity
C7Y67_20775	COG1929	Belongs to the glycerate kinase type-1 family
C7Y67_20780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7Y67_20800	COG0456	acetyltransferase
C7Y67_20815	COG1028	Short-chain dehydrogenase reductase Sdr
C7Y67_20825	COG3005	denitrification pathway
C7Y67_20830	COG0243	molybdopterin cofactor binding
C7Y67_20840	COG0352	thiamine-phosphate diphosphorylase activity
C7Y67_20845	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C7Y67_20850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7Y67_20855	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7Y67_20860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7Y67_20865	COG1116	anion transmembrane transporter activity
C7Y67_20870	COG0351	phosphomethylpyrimidine kinase
C7Y67_20880	COG0312	modulator of DNA gyrase
C7Y67_20885	COG0312	modulator of DNA gyrase
C7Y67_20890	COG1901	pseudouridine methyltransferase
C7Y67_20950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7Y67_20960	COG0584	glycerophosphoryl diester phosphodiesterase
C7Y67_20970	COG0745	RESPONSE REGULATOR receiver
C7Y67_20990	COG0811	peptide transport
C7Y67_20995	COG0811	peptide transport
C7Y67_21000	COG0848	biopolymer transport protein
C7Y67_21040	COG0803	Belongs to the bacterial solute-binding protein 9 family
C7Y67_21045	COG1121	(ABC) transporter
C7Y67_21050	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7Y67_21065	COG1770	oligopeptidase
C7Y67_21070	COG2814	Major facilitator Superfamily
C7Y67_21075	COG0010	Belongs to the arginase family
C7Y67_21080	COG1166	arginine decarboxylase activity
C7Y67_21090	COG0189	ligase activity
C7Y67_21090	COG4067	protein conserved in archaea
C7Y67_21095	COG0189	ligase activity
C7Y67_21105	COG0583	DNA-binding transcription factor activity
C7Y67_21140	COG4191	Histidine kinase
C7Y67_21150	COG3706	GGDEF domain
C7Y67_21180	COG0579	oxidoreductase
C7Y67_21190	COG3033	Beta-eliminating lyase
C7Y67_21210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7Y67_21220	COG3145	DNA-N1-methyladenine dioxygenase activity
C7Y67_21225	COG3706	GGDEF domain
C7Y67_21230	COG0840	transmembrane signaling receptor activity
C7Y67_21245	COG3706	GGDEF domain
C7Y67_21250	COG0415	Belongs to the DNA photolyase family
C7Y67_21255	COG3046	protein related to deoxyribodipyrimidine photolyase
C7Y67_21270	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7Y67_21270	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7Y67_21275	COG1765	OsmC-like protein
C7Y67_21280	COG0110	maltose O-acetyltransferase activity
C7Y67_21320	COG1011	Hydrolase
C7Y67_21335	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C7Y67_21345	COG2067	long-chain fatty acid transport protein
C7Y67_21350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7Y67_21355	COG0577	efflux transmembrane transporter activity
C7Y67_21355	COG1136	(ABC) transporter
C7Y67_21365	COG3240	lipase activity
C7Y67_21395	COG1609	Transcriptional regulator
C7Y67_21400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7Y67_21410	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7Y67_21415	COG1840	ABC-type Fe3 transport system, periplasmic component
C7Y67_21425	COG3842	ATPase activity
C7Y67_21450	COG2990	Protein conserved in bacteria
C7Y67_21460	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7Y67_21465	COG2866	Carboxypeptidase
C7Y67_21480	COG0583	DNA-binding transcription factor activity
C7Y67_21505	COG1760	l-serine dehydratase
C7Y67_21525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7Y67_21530	COG0741	lytic transglycosylase activity
C7Y67_21550	COG1815	bacterial-type flagellum-dependent cell motility
C7Y67_21555	COG1558	bacterial-type flagellum-dependent cell motility
C7Y67_21560	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C7Y67_21565	COG1749	Flagellar hook protein flgE
C7Y67_21570	COG4787	bacterial-type flagellum-dependent cell motility
C7Y67_21575	COG4786	Flagellar basal body rod
C7Y67_21580	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C7Y67_21585	COG1706	bacterial-type flagellum-dependent cell motility
C7Y67_21600	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C7Y67_21620	COG1304	FMN binding
C7Y67_21645	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7Y67_21650	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7Y67_21655	COG0459	protein refolding
C7Y67_21670	COG1280	lysine exporter protein (LysE YggA)
C7Y67_21690	COG1309	transcriptional regulator
C7Y67_21700	COG0737	Belongs to the 5'-nucleotidase family
C7Y67_21705	COG2070	2-Nitropropane dioxygenase
C7Y67_21710	COG3537	Alpha-1,2-mannosidase
C7Y67_21715	COG3537	Alpha-1,2-mannosidase
C7Y67_21725	COG3537	Alpha-1,2-mannosidase
C7Y67_21730	COG3537	Alpha-1,2-mannosidase
C7Y67_21735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7Y67_21750	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7Y67_21750	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7Y67_21755	COG0346	lactoylglutathione lyase activity
C7Y67_21760	COG1349	DNA-binding transcription factor activity
C7Y67_21770	COG0753	catalase activity
C7Y67_21780	COG1335	isochorismatase
C7Y67_21790	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C7Y67_21815	COG0583	DNA-binding transcription factor activity
C7Y67_21830	COG3713	MltA-interacting MipA family protein
C7Y67_21840	COG3015	lipoprotein NlpE involved in copper resistance
C7Y67_21850	COG1342	Belongs to the UPF0251 family
C7Y67_21875	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7Y67_21885	COG4948	Mandelate Racemase Muconate Lactonizing
C7Y67_21895	COG0583	DNA-binding transcription factor activity
C7Y67_21945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7Y67_21990	COG3842	ATPase activity
C7Y67_22020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7Y67_22040	COG3706	GGDEF domain
C7Y67_22060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7Y67_22075	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C7Y67_22080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7Y67_22100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7Y67_22100	COG0574	Belongs to the PEP-utilizing enzyme family
C7Y67_22105	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7Y67_22110	COG0252	asparaginase activity
C7Y67_22120	COG0583	DNA-binding transcription factor activity
C7Y67_22140	COG3122	Protein conserved in bacteria
C7Y67_22155	COG1028	Short-chain dehydrogenase reductase Sdr
C7Y67_22165	COG1063	alcohol dehydrogenase
C7Y67_22170	COG1902	pentaerythritol trinitrate reductase activity
C7Y67_22185	COG0583	DNA-binding transcription factor activity
C7Y67_22195	COG0513	Belongs to the DEAD box helicase family
C7Y67_22240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7Y67_22245	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7Y67_22245	COG2207	Transcriptional regulator
C7Y67_22275	COG2354	Protein conserved in bacteria
C7Y67_22280	COG0418	dihydroorotase activity
C7Y67_22290	COG0401	homolog of Blt101
C7Y67_22300	COG0633	Ferredoxin
C7Y67_22300	COG3217	Mosc domain protein beta barrel domain protein
C7Y67_22300	COG0633	Ferredoxin
C7Y67_22300	COG3217	Mosc domain protein beta barrel domain protein
C7Y67_22305	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7Y67_22310	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7Y67_22355	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C7Y67_22360	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7Y67_22370	COG0848	biopolymer transport protein
C7Y67_22375	COG0811	peptide transport
C7Y67_22380	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C7Y67_22390	COG3721	Heme iron utilization protein
C7Y67_22395	COG0748	coenzyme F420 binding
C7Y67_22405	COG0835	chemotaxis
C7Y67_22405	COG0784	Response regulator, receiver
C7Y67_22415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7Y67_22425	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C7Y67_22425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7Y67_22450	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C7Y67_22455	COG0783	Belongs to the Dps family
C7Y67_22465	COG0583	DNA-binding transcription factor activity
C7Y67_22480	COG4934	collagen metabolic process
C7Y67_22490	COG0366	Alpha amylase catalytic
C7Y67_22510	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7Y67_22515	COG0589	response to stress
C7Y67_22520	COG0488	(ABC) transporter
C7Y67_22535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7Y67_22545	COG2067	long-chain fatty acid transport protein
C7Y67_22555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7Y67_22565	COG2203	Gaf domain
C7Y67_22565	COG2199	diguanylate cyclase activity
C7Y67_22585	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7Y67_22610	COG3383	formate dehydrogenase (NAD+) activity
C7Y67_22625	COG0842	Transport permease protein
C7Y67_22630	COG1131	(ABC) transporter
C7Y67_22640	COG0840	transmembrane signaling receptor activity
C7Y67_22655	COG2706	6-phosphogluconolactonase activity
C7Y67_22665	COG1881	PFAM PEBP family protein
C7Y67_22675	COG0798	PFAM Bile acid sodium symporter
C7Y67_22695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7Y67_22700	COG2213	PTS system mannitol-specific
C7Y67_22705	COG1063	alcohol dehydrogenase
C7Y67_22715	COG1072	(Pantothenic acid kinase))
C7Y67_22720	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7Y67_22740	COG0814	amino acid
C7Y67_22780	COG0739	heme binding
C7Y67_22785	COG5001	Diguanylate cyclase
C7Y67_22790	COG0583	DNA-binding transcription factor activity
C7Y67_22795	COG2814	Major facilitator Superfamily
C7Y67_22820	COG0697	spore germination
C7Y67_22850	COG2207	Transcriptional regulator
C7Y67_22855	COG1280	lysine exporter protein (LysE YggA)
C7Y67_22865	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7Y67_22870	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7Y67_22880	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C7Y67_22905	COG1612	heme a metabolic process
C7Y67_22910	COG0109	protoheme IX farnesyltransferase activity
C7Y67_22915	COG0545	Peptidyl-prolyl cis-trans isomerase
C7Y67_22950	COG1278	Cold shock
C7Y67_22955	COG3036	rescue of stalled ribosome
C7Y67_22970	COG2199	diguanylate cyclase activity
C7Y67_22990	COG1136	(ABC) transporter
C7Y67_22990	COG0577	efflux transmembrane transporter activity
C7Y67_23000	COG0840	transmembrane signaling receptor activity
C7Y67_23010	COG0783	Belongs to the Dps family
C7Y67_23020	COG2133	pyrroloquinoline quinone binding
C7Y67_23025	COG1454	alcohol dehydrogenase
C7Y67_23030	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C7Y67_23065	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7Y67_23070	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7Y67_23075	COG3186	Phenylalanine-4-hydroxylase
C7Y67_23080	COG2154	pterin-4-alpha-carbinolamine dehydratase
C7Y67_23105	COG3530	Putative quorum-sensing-regulated virulence factor
C7Y67_23110	COG0513	Belongs to the DEAD box helicase family
C7Y67_23115	COG4628	conserved protein (DUF2132)
C7Y67_23120	COG0133	tryptophan synthase activity
C7Y67_23130	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C7Y67_23140	COG0523	cobalamin synthesis protein
C7Y67_23145	COG0513	Belongs to the DEAD box helicase family
C7Y67_23165	COG2200	EAL domain
C7Y67_23170	COG1119	ATPase activity
C7Y67_23175	COG0840	transmembrane signaling receptor activity
C7Y67_23195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7Y67_23210	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
C7Y67_23215	COG0513	Belongs to the DEAD box helicase family
C7Y67_23220	COG5001	Diguanylate cyclase
C7Y67_23230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7Y67_23245	COG5413	integral membrane protein
C7Y67_23255	COG1024	Enoyl-CoA hydratase
C7Y67_23260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7Y67_23265	COG1960	acyl-CoA dehydrogenase activity
C7Y67_23275	COG0183	Belongs to the thiolase family
C7Y67_23290	COG1024	Enoyl-CoA hydratase
C7Y67_23295	COG1024	Enoyl-CoA hydratase
C7Y67_23305	COG1028	Short-chain dehydrogenase reductase Sdr
C7Y67_23310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7Y67_23315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7Y67_23320	COG1845	cytochrome c oxidase, subunit III
C7Y67_23325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7Y67_23330	COG0109	protoheme IX farnesyltransferase activity
C7Y67_23335	COG1902	pentaerythritol trinitrate reductase activity
C7Y67_23365	COG1126	abc transporter atp-binding protein
C7Y67_23370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7Y67_23375	COG4215	(ABC) transporter
C7Y67_23380	COG4160	amino acid transport
C7Y67_23395	COG0625	glutathione transferase activity
C7Y67_23430	COG0443	Heat shock 70 kDa protein
C7Y67_23435	COG2847	Copper chaperone PCu(A)C
C7Y67_23460	COG4607	ABC-type enterochelin transport system periplasmic component
C7Y67_23465	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7Y67_23470	COG4605	iron ion homeostasis
C7Y67_23475	COG4604	ABC transporter, ATP-binding protein
C7Y67_23480	COG0789	Transcriptional regulator
C7Y67_23495	COG4206	TonB-dependent receptor
C7Y67_23530	COG1289	transmembrane transporter activity
C7Y67_23535	COG0210	DNA helicase
C7Y67_23540	COG1803	Methylglyoxal synthase
C7Y67_23545	COG1879	ABC-type sugar transport system periplasmic component
C7Y67_23550	COG2205	protein histidine kinase activity
C7Y67_23550	COG2198	Histidine kinase
C7Y67_23550	COG0784	Response regulator, receiver
C7Y67_23565	COG0745	RESPONSE REGULATOR receiver
C7Y67_23570	COG3119	arylsulfatase activity
C7Y67_23575	COG3119	arylsulfatase activity
C7Y67_23590	COG3119	arylsulfatase activity
C7Y67_23595	COG0641	radical SAM
C7Y67_23600	COG0714	Associated with various cellular activities
C7Y67_23630	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7Y67_23630	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7Y67_23635	COG0583	DNA-binding transcription factor activity
C7Y67_23640	COG1597	lipid kinase activity
C7Y67_23645	COG3111	PFAM Bacterial OB fold (BOF) protein
C7Y67_23665	COG0641	radical SAM
C7Y67_23695	COG0501	Belongs to the peptidase M48B family
C7Y67_23700	COG1704	LemA family
C7Y67_23705	COG3069	C4-dicarboxylate transmembrane transporter activity
C7Y67_23735	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7Y67_23780	COG4964	Belongs to the GSP D family
C7Y67_23855	COG5001	Diguanylate cyclase
C7Y67_23855	COG3300	MHYT domain
C7Y67_23860	COG2197	response regulator
C7Y67_23865	COG3706	GGDEF domain
C7Y67_23875	COG2197	response regulator
C7Y67_23900	COG0784	Response regulator, receiver
C7Y67_23900	COG0835	chemotaxis
C7Y67_23920	COG2962	Rard protein
C7Y67_23935	COG0671	phosphoesterase, PA-phosphatase related
C7Y67_23950	COG2076	Multidrug Resistance protein
C7Y67_23980	COG0471	metal ion transport
C7Y67_23985	COG3290	protein histidine kinase activity
C7Y67_23990	COG4565	transcriptional regulatory protein
C7Y67_24000	COG0069	glutamate synthase activity
C7Y67_24000	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C7Y67_24010	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C7Y67_24035	COG1902	pentaerythritol trinitrate reductase activity
C7Y67_24040	COG0346	lactoylglutathione lyase activity
C7Y67_24060	COG2239	Acts as a magnesium transporter
C7Y67_24090	COG0242	peptide deformylase activity
C7Y67_24135	COG2176	DNA-directed DNA polymerase activity
C7Y67_24140	COG0583	DNA-binding transcription factor activity
C7Y67_24145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7Y67_24150	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C7Y67_24190	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7Y67_24190	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7Y67_24195	COG0509	glycine decarboxylation via glycine cleavage system
C7Y67_24200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7Y67_24245	COG1105	Belongs to the carbohydrate kinase PfkB family
C7Y67_24250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7Y67_24250	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7Y67_24255	COG1609	Transcriptional regulator
C7Y67_24275	COG2199	diguanylate cyclase activity
C7Y67_24275	COG2200	EAL domain
C7Y67_24275	COG2203	Gaf domain
C7Y67_24280	COG0765	amino acid transport
C7Y67_24285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7Y67_24290	COG0765	amino acid transport
C7Y67_24295	COG1126	abc transporter atp-binding protein
C7Y67_24300	COG0469	pyruvate kinase activity
C7Y67_24305	COG2271	Major facilitator Superfamily
C7Y67_24310	COG1840	ABC-type Fe3 transport system, periplasmic component
C7Y67_24330	COG1979	alcohol dehydrogenase
C7Y67_24335	COG2207	Transcriptional regulator
C7Y67_24350	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7Y67_24355	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C7Y67_24360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7Y67_24380	COG0784	Response regulator, receiver
C7Y67_24380	COG3437	response regulator, receiver
C7Y67_24390	COG0546	phosphoglycolate phosphatase activity
C7Y67_24400	COG0840	transmembrane signaling receptor activity
C7Y67_24410	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
C7Y67_24415	COG0513	Belongs to the DEAD box helicase family
C7Y67_24420	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C7Y67_24435	COG3038	cytochrome b561
C7Y67_24440	COG2353	YceI-like domain
C7Y67_24445	COG2116	formate transmembrane transporter activity
C7Y67_24450	COG0583	DNA-binding transcription factor activity
C7Y67_24460	COG3593	DNA synthesis involved in DNA repair
C7Y67_24465	COG0737	Belongs to the 5'-nucleotidase family
C7Y67_24470	COG0861	Integral membrane protein TerC family
C7Y67_24485	COG2267	carboxylic ester hydrolase activity
C7Y67_24490	COG2067	long-chain fatty acid transport protein
C7Y67_24505	COG2050	protein possibly involved in aromatic compounds catabolism
C7Y67_24515	COG4533	DNA binding
C7Y67_24540	COG0484	heat shock protein binding
C7Y67_24550	COG5001	Diguanylate cyclase
C7Y67_24550	COG3300	MHYT domain
C7Y67_24555	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7Y67_24565	COG4181	ATPase activity
C7Y67_24570	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C7Y67_24580	COG1984	allophanate hydrolase subunit 2
C7Y67_24585	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C7Y67_24590	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C7Y67_24595	COG5001	Diguanylate cyclase
C7Y67_24595	COG3447	MASE1 domain protein
C7Y67_24595	COG5002	protein histidine kinase activity
C7Y67_24600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7Y67_24615	COG0583	DNA-binding transcription factor activity
C7Y67_24620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7Y67_24620	COG0045	succinate-CoA ligase (ADP-forming) activity
C7Y67_24620	COG1042	CoA-binding domain protein
C7Y67_24630	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7Y67_24640	COG0023	Translation Initiation Factor
C7Y67_24655	COG0583	DNA-binding transcription factor activity
C7Y67_24665	COG0589	response to stress
C7Y67_24670	COG3140	Belongs to the UPF0181 family
C7Y67_24695	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C7Y67_24700	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C7Y67_24715	COG0745	RESPONSE REGULATOR receiver
C7Y67_24715	COG3706	GGDEF domain
C7Y67_24725	COG3706	GGDEF domain
C7Y67_24725	COG4251	negative regulation of phosphorylation
C7Y67_24725	COG2203	Gaf domain
C7Y67_24725	COG5001	Diguanylate cyclase
C7Y67_24735	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C7Y67_24740	COG4149	molybdate abc transporter
C7Y67_24745	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7Y67_24750	COG1492	cobalamin metabolic process
C7Y67_24755	COG3111	PFAM Bacterial OB fold (BOF) protein
C7Y67_24765	COG4067	protein conserved in archaea
C7Y67_24765	COG0189	ligase activity
C7Y67_24785	COG0534	Mate efflux family protein
C7Y67_24790	COG0602	queuosine metabolic process
C7Y67_24795	COG1328	CTP reductase activity
C7Y67_24810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7Y67_24845	COG3550	peptidyl-serine autophosphorylation
C7Y67_24935	COG4735	regulation of single-species biofilm formation
C7Y67_24975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7Y67_24980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7Y67_25030	COG3706	GGDEF domain
C7Y67_25075	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7Y67_25080	COG0243	molybdopterin cofactor binding
C7Y67_25090	COG0583	DNA-binding transcription factor activity
C7Y67_25095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7Y67_25105	COG2197	response regulator
C7Y67_25110	COG3851	Histidine kinase
C7Y67_25115	COG2271	Major facilitator Superfamily
C7Y67_25140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7Y67_25145	COG3118	belongs to the thioredoxin family
C7Y67_25150	COG2814	Major facilitator Superfamily
C7Y67_25160	COG0534	Mate efflux family protein
C7Y67_25195	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C7Y67_25215	COG2116	formate transmembrane transporter activity
C7Y67_25220	COG2146	nitrite reductase [NAD(P)H] activity
C7Y67_25225	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7Y67_25230	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7Y67_25275	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C7Y67_25275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7Y67_25315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7Y67_25335	COG0277	FAD linked oxidase domain protein
C7Y67_25340	COG0583	DNA-binding transcription factor activity
C7Y67_25360	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C7Y67_25375	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C7Y67_25390	COG1288	antiporter activity
C7Y67_25400	COG2814	Major facilitator Superfamily
C7Y67_25410	COG3040	lipid binding
C7Y67_25430	COG0419	ATPase involved in DNA repair
C7Y67_25435	COG0420	3'-5' exonuclease activity
C7Y67_25450	COG3501	Rhs element vgr protein
C7Y67_25505	COG0631	protein serine/threonine phosphatase activity
C7Y67_25540	COG2815	serine threonine protein kinase
C7Y67_25540	COG0515	serine threonine protein kinase
C7Y67_25595	COG2146	nitrite reductase [NAD(P)H] activity
C7Y67_25595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7Y67_25600	COG1116	anion transmembrane transporter activity
C7Y67_25605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7Y67_25610	COG1116	anion transmembrane transporter activity
C7Y67_25610	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7Y67_25620	COG3707	response regulator
C7Y67_25640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7Y67_25640	COG1648	precorrin-2 dehydrogenase activity
C7Y67_25645	COG0243	molybdopterin cofactor binding
C7Y67_25650	COG0456	acetyltransferase
C7Y67_25655	COG0814	amino acid
C7Y67_25665	COG3706	GGDEF domain
C7Y67_25665	COG0745	RESPONSE REGULATOR receiver
C7Y67_25685	COG1785	Belongs to the alkaline phosphatase family
C7Y67_25700	COG0745	RESPONSE REGULATOR receiver
C7Y67_25720	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C7Y67_25735	COG1609	Transcriptional regulator
C7Y67_25740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7Y67_25745	COG1879	ABC-type sugar transport system periplasmic component
C7Y67_25750	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7Y67_25755	COG1129	ABC transporter
C7Y67_25760	COG1869	D-ribose catabolic process
C7Y67_25765	COG5001	Diguanylate cyclase
C7Y67_25770	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7Y67_25905	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
C7Y67_25945	COG0582	viral genome integration into host DNA
C7Y67_25960	COG0681	Belongs to the peptidase S26 family
C7Y67_25975	COG2948	multi-organism process
C7Y67_25990	COG3701	Conjugal transfer protein
C7Y67_26010	COG3451	type IV secretory pathway VirB4
C7Y67_26035	COG1192	Involved in chromosome partitioning
C7Y67_26075	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C7Y67_26095	COG3706	GGDEF domain
C7Y67_26125	COG2003	Belongs to the UPF0758 family
C7Y67_26150	COG2003	Belongs to the UPF0758 family
C7Y67_26170	COG4962	Type ii secretion system protein e
C7Y67_26245	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7Y67_26505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7Y67_26540	COG3504	Conjugal transfer protein
C7Y67_26555	COG4962	Type ii secretion system protein e
C7Y67_26565	COG3451	type IV secretory pathway VirB4
C7Y67_26570	COG5268	conjugation
C7Y67_26615	COG1192	Involved in chromosome partitioning
C7Y67_26640	COG0419	ATPase involved in DNA repair