locus-tag	class	description
C9I78_00010	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C9I78_00020	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C9I78_00030	ENOG4105PM1	preprotein translocase subunit SecE
C9I78_00035	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
C9I78_00040	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
C9I78_00045	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
C9I78_00050	ENOG4108VZM	50s ribosomal protein L10
C9I78_00055	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
C9I78_00060	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C9I78_00065	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C9I78_00070	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
C9I78_00075	ENOG4105E09	nadh pyrophosphatase
C9I78_00090	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
C9I78_00095	ENOG4108RG0	uracil-dna glycosylase
C9I78_00100	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
C9I78_00105	ENOG4105R2J	Conserved Protein
C9I78_00125	ENOG4105C12	Phosphoribosylglycinamide synthetase
C9I78_00135	ENOG4105DC1	bifunctional purine biosynthesis protein purh
C9I78_00145	ENOG4105W1Y	Transcriptional regulator
C9I78_00150	ENOG4108M3R	transcriptional activator CadC
C9I78_00160	ENOG4105D5Q	Arginine ornithine antiporter
C9I78_00165	ENOG4105CXN	decarboxylase
C9I78_00230	ENOG4105BZU	Histidine kinase
C9I78_00245	ENOG4105C5H	ABC transporter
C9I78_00250	ENOG4107XZQ	multidrug resistance protein
C9I78_00260	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C9I78_00315	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
C9I78_00320	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C9I78_00325	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C9I78_00335	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
C9I78_00340	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
C9I78_00345	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
C9I78_00350	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C9I78_00365	ENOG4105D8G	Major Facilitator superfamily
C9I78_00370	ENOG4105BZU	Histidine kinase
C9I78_00375	ENOG4105C9Q	fumarate hydratase class II
C9I78_00395	ENOG4107QN1	sodium solute
C9I78_00405	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
C9I78_00415	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
C9I78_00420	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
C9I78_00425	ENOG4108IJ0	Aspartate ammonia-lyase
C9I78_00430	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
C9I78_00435	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
C9I78_00445	ENOG4105E0F	Histidine kinase
C9I78_00450	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C9I78_00460	ENOG4108SPG	Periplasmic Protein
C9I78_00465	ENOG41076HS	cation diffusion facilitator family transporter
C9I78_00470	ENOG4105CTQ	phosphohexokinase
C9I78_00475	ENOG4107QI1	Mate efflux family protein
C9I78_00480	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C9I78_00485	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C9I78_00495	ENOG4105KT7	mgtC SapB transporter
C9I78_00505	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C9I78_00515	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
C9I78_00520	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C9I78_00530	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
C9I78_00535	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
C9I78_00540	ENOG4105E33	succinate dehydrogenase
C9I78_00555	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
C9I78_00565	ENOG41062JF	Transcriptional regulator
C9I78_00575	ENOG41063SB	peptidase
C9I78_00580	ENOG4105D7W	serine acetyltransferase
C9I78_00585	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
C9I78_00590	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
C9I78_00595	ENOG4107YZP	Rhodanese domain protein
C9I78_00600	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
C9I78_00610	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_00615	ENOG4105C8P	)-transporter
C9I78_00620	ENOG4105DJ4	phosphatidylserine decarboxylase
C9I78_00625	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C9I78_00630	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
C9I78_00700	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
C9I78_00705	ENOG4105K8N	protein family UPF0079, ATPase
C9I78_00710	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
C9I78_00715	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
C9I78_00720	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
C9I78_00725	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
C9I78_00730	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
C9I78_00735	ENOG4107QJR	hflk protein
C9I78_00740	ENOG4105EPW	hflc protein
C9I78_00750	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C9I78_00760	ENOG4108UV7	flagellar protein motX
C9I78_00765	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C9I78_00770	ENOG4105KPV	Transcriptional regulator
C9I78_00775	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
C9I78_00780	ENOG4105C2N	RNA methyltransferase TrmH family group 3
C9I78_00785	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C9I78_00790	ENOG4105C31	Tryptophanyl-tRNA synthetase
C9I78_00820	ENOG4105DDQ	anthranilate synthase
C9I78_00825	ENOG4105C8Y	Acetylornithine aminotransferase
C9I78_00835	ENOG4105C26	Dehydrogenase
C9I78_00845	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
C9I78_00850	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
C9I78_00855	ENOG4105YP7	UPF0270 protein
C9I78_00860	ENOG4105DNZ	Alpha Beta Hydrolase
C9I78_00870	ENOG4105C5H	ABC transporter
C9I78_00880	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
C9I78_00895	ENOG4108YZY	peptidylprolyl cis-trans isomerase
C9I78_00905	ENOG4105D44	asparaginase
C9I78_00910	ENOG41069P5	Protein slyX homolog
C9I78_00920	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C9I78_00925	ENOG4105WWK	YheO domain protein
C9I78_00930	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
C9I78_00935	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
C9I78_00940	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
C9I78_00945	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
C9I78_00950	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
C9I78_00955	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C9I78_00960	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
C9I78_00965	ENOG4105W53	bacterioferritin-associated ferredoxin
C9I78_00970	ENOG4108UQY	Iron-storage protein
C9I78_00975	ENOG4105C6K	Malic enzyme
C9I78_00980	ENOG4105GGQ	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity)
C9I78_00985	ENOG4105C28	cystathionine
C9I78_00990	ENOG4105CFH	Aspartokinase
C9I78_00995	ENOG4105SYT	Methylenetetrahydrofolate reductase
C9I78_01005	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
C9I78_01010	ENOG4105CWC	Acetylornithine deacetylase
C9I78_01015	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C9I78_01020	ENOG4105CAS	nag kinase
C9I78_01025	ENOG4105CDH	Citrulline--aspartate ligase
C9I78_01030	ENOG4105CH7	arginosuccinase
C9I78_01045	ENOG4105EHV	domain protein
C9I78_01055	ENOG4108JQC	penicillin-binding protein 1A
C9I78_01080	ENOG4105E4G	Type IV pilus
C9I78_01085	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
C9I78_01090	ENOG4105D49	3-dehydroquinate synthase
C9I78_01100	ENOG4105DFE	Dna adenine methylase
C9I78_01105	ENOG4105DJV	ribulose-phosphate 3-epimerase
C9I78_01115	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
C9I78_01120	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
C9I78_01125	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
C9I78_01130	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
C9I78_01140	ENOG4105CDU	Replicative dna helicase
C9I78_01145	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C9I78_01155	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
C9I78_01160	ENOG4107QP8	phosphohexose isomerase
C9I78_01170	ENOG4105MYN	Zinc uptake regulation protein
C9I78_01180	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
C9I78_01205	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
C9I78_01210	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
C9I78_01215	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
C9I78_01295	ENOG4105EEQ	Na H antiporter
C9I78_01300	ENOG4105C3R	Methionine synthase
C9I78_01305	ENOG4105CFH	Aspartokinase
C9I78_01315	ENOG4105C5R	Aminotransferase
C9I78_01325	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
C9I78_01330	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C9I78_01335	ENOG41086KC	Transcriptional regulator
C9I78_01340	ENOG4108UUM	single-stranded DNA-binding protein
C9I78_01370	ENOG4105C7H	Helicase, RecD TraA family
C9I78_01390	ENOG41062P1	Diguanylate cyclase phosphodiesterase
C9I78_01410	ENOG4105E4G	Type IV pilus
C9I78_01425	ENOG4107QHF	type ii secretion system protein e
C9I78_01430	ENOG4105D7Q	type ii secretion system
C9I78_01475	ENOG4105DFF	Rod shape-determining protein mreb
C9I78_01480	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
C9I78_01485	ENOG4105VQ7	Rod shape-determining protein MreD
C9I78_01490	ENOG4108Z03	MAF-like protein
C9I78_01495	ENOG4105C03	ribonuclease
C9I78_01500	ENOG4105QD6	exported protein
C9I78_01510	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
C9I78_01515	ENOG4108IAB	Phoh family
C9I78_01520	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
C9I78_01525	ENOG4105K3M	)-transporter
C9I78_01535	ENOG4105D3G	Pseudouridine synthase
C9I78_01540	ENOG4105C5I	Dehydrogenase
C9I78_01545	ENOG4105N42	UPF0307 protein
C9I78_01550	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
C9I78_01555	ENOG4105CJW	magnesium transporter
C9I78_01560	ENOG41080Z8	PHOSPHOCARRIER protein
C9I78_01565	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
C9I78_01570	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
C9I78_01575	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
C9I78_01580	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C9I78_01585	ENOG4108IUZ	ABC transporter
C9I78_01590	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
C9I78_01600	ENOG4105C2X	Arabinose 5-phosphate isomerase
C9I78_01610	ENOG4105DHJ	ABC, transporter
C9I78_01615	ENOG4105CY3	ABC transporter, permease
C9I78_01620	ENOG4107PE3	Mammalian cell entry related domain protein
C9I78_01625	ENOG4105E3I	toluene tolerance
C9I78_01635	ENOG4105VFK	BolA family
C9I78_01640	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
C9I78_01645	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
C9I78_01650	ENOG4105KME	endoribonuclease L-psp
C9I78_01655	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
C9I78_01660	ENOG4105CXT	aspartate transcarbamylase
C9I78_01670	ENOG4105DBV	ornithine carbamoyltransferase
C9I78_01675	ENOG4105CEU	Arginine dihydrolase
C9I78_01745	ENOG4108MJ3	acetyltransferase
C9I78_01755	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
C9I78_01760	ENOG4105MYG	DNA polymerase iii, chi subunit
C9I78_01765	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C9I78_01770	ENOG4108M8S	permease YjgP YjgQ family protein
C9I78_01775	ENOG4108K5H	permease YjgP YjgQ family protein
C9I78_01785	ENOG4105EXU	Membrane
C9I78_01790	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
C9I78_01810	ENOG4105VZJ	PTS System
C9I78_01815	ENOG4105CK1	PTS System
C9I78_01820	ENOG4105VCP	PTS System
C9I78_01825	ENOG4105F8D	glycoside hydrolase family 4
C9I78_01830	ENOG410901P	UPF0249 protein
C9I78_01840	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C9I78_01890	ENOG4105C26	Dehydrogenase
C9I78_01920	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_01960	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
C9I78_01965	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
C9I78_01970	ENOG4105CEN	a g-specific adenine glycosylase
C9I78_01975	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
C9I78_01985	ENOG4105CSV	Glutaminase
C9I78_01990	ENOG4105CSA	Coproporphyrinogen iii oxidase
C9I78_01995	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C9I78_02005	ENOG4105VZ9	UPF0235 protein
C9I78_02010	ENOG4108VIA	integral membrane protein
C9I78_02015	ENOG4105II7	pyrroline-5-carboxylate reductase
C9I78_02020	ENOG4105DFA	alanine racemase domain protein
C9I78_02025	ENOG4105CZX	twitching motility protein
C9I78_02030	ENOG4105CZX	twitching motility protein
C9I78_02035	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
C9I78_02040	ENOG4108UJU	UPF0301 protein
C9I78_02045	ENOG4105D7Z	glutathione synthase
C9I78_02050	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
C9I78_02055	ENOG4105RWS	endonuclease I
C9I78_02060	ENOG4105GPY	SprT protein
C9I78_02070	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
C9I78_02080	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C9I78_02085	ENOG4108R4R	Iron-regulated virulence regulatory protein
C9I78_02090	ENOG4105D05	Receptor
C9I78_02095	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C9I78_02100	ENOG4105BZA	Phosphoglycerate kinase
C9I78_02105	ENOG4105D2N	Aldolase
C9I78_02110	ENOG4105D64	Mechanosensitive ion channel
C9I78_02115	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
C9I78_02125	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
C9I78_02130	ENOG4105MPN	Membrane
C9I78_02135	ENOG4108JQ1	Dehydrogenase
C9I78_02140	ENOG4105E66	phosphoriboisomerase A
C9I78_02145	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
C9I78_02155	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
C9I78_02170	ENOG4105D0A	hydroxylase
C9I78_02175	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
C9I78_02190	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
C9I78_02195	ENOG4105Y75	tpr repeat protein
C9I78_02205	ENOG4108IYU	L-aspartate oxidase
C9I78_02215	ENOG4105EMN	RNA polymerase sigma factor
C9I78_02220	ENOG41069PW	sigma-e factor negative regulatory protein
C9I78_02235	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
C9I78_02240	ENOG4105C3F	Signal peptidase i
C9I78_02245	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
C9I78_02250	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
C9I78_02255	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
C9I78_02260	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
C9I78_02265	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
C9I78_02270	ENOG4105BZU	Histidine kinase
C9I78_02280	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C9I78_02290	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C9I78_02295	ENOG4105DXN	mazG family
C9I78_02300	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
C9I78_02305	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
C9I78_02310	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C9I78_02315	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
C9I78_02320	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
C9I78_02325	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
C9I78_02330	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
C9I78_02335	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
C9I78_02350	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
C9I78_02355	ENOG4107TH8	cina domain protein
C9I78_02365	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
C9I78_02430	ENOG4105Y3E	Modulates RecA activity (By similarity)
C9I78_02435	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
C9I78_02440	ENOG4105CFH	Aspartokinase
C9I78_02445	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
C9I78_02500	ENOG4106AFN	Lyase and sodium transporter (By similarity)
C9I78_02505	ENOG4107QSA	Oxaloacetate decarboxylase
C9I78_02510	ENOG4105D9Q	decarboxylase (Beta subunit)
C9I78_02515	ENOG4105CPQ	Dehydrogenase
C9I78_02520	ENOG4105W39	Membrane
C9I78_02530	ENOG4105D9M	gamma-glutamylcysteine synthetase
C9I78_02540	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
C9I78_02545	ENOG4108JU6	CBS domain protein
C9I78_02550	ENOG4106KVJ	cytochrome C assembly protein
C9I78_02555	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C9I78_02560	ENOG4105K5M	30s ribosomal protein S16
C9I78_02565	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
C9I78_02570	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
C9I78_02575	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
C9I78_02580	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
C9I78_02585	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
C9I78_02590	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
C9I78_02595	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
C9I78_02600	ENOG4105D7Q	type ii secretion system
C9I78_02605	ENOG4107QHF	type ii secretion system protein e
C9I78_02610	ENOG4105X0D	Fimbrial protein
C9I78_02615	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
C9I78_02625	ENOG41073TP	transcriptional regulator
C9I78_02630	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
C9I78_02635	ENOG4107QSN	dihydrolipoamide acetyltransferase
C9I78_02640	ENOG4107QN2	dihydrolipoyl dehydrogenase
C9I78_02645	ENOG410630P	Transcriptional regulator
C9I78_02650	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
C9I78_02655	ENOG41077A9	carbonic anhydrase
C9I78_02660	ENOG4105CHH	sulfate transporter
C9I78_02670	ENOG4105DA5	(ABC) transporter
C9I78_02675	ENOG4105E3A	(ABC) transporter
C9I78_02685	ENOG4105D1S	lipid A biosynthesis
C9I78_02695	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
C9I78_02700	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
C9I78_02705	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C9I78_02710	ENOG4105DJ0	Poly(A) Polymerase
C9I78_02720	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
C9I78_02730	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9I78_02735	ENOG4105PW4	Sugar fermentation stimulation protein homolog
C9I78_02775	ENOG4105CAF	HipA N-terminal domain protein
C9I78_02845	ENOG4105BZ4	penicillin-binding protein
C9I78_02850	ENOG4105D78	K07001 NTE family protein
C9I78_02855	ENOG4107QIJ	Aconitate hydratase 2
C9I78_02860	ENOG4105XTV	UPF0231 protein
C9I78_02865	ENOG4108YZA	Nitrogen regulatory protein pii
C9I78_02885	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C9I78_02890	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C9I78_02900	ENOG4105E2D	ec 3.2.1.52
C9I78_02905	ENOG4105RD7	BadF BadG BcrA BcrD
C9I78_02915	ENOG4108JQ7	(ABC) transporter
C9I78_02920	ENOG4105C3U	ABC transporter
C9I78_02925	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C9I78_02935	ENOG4107QRA	Extracellular solute-binding protein, family 5
C9I78_02940	ENOG4105BZU	Histidine kinase
C9I78_02950	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C9I78_02955	ENOG4105IPI	Membrane
C9I78_02960	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
C9I78_02965	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
C9I78_02975	ENOG4105BZS	acriflavin resistance protein
C9I78_02980	ENOG4105DR5	peptidase
C9I78_02985	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C9I78_02995	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
C9I78_03000	ENOG4107QE9	Inherit from COG: Membrane
C9I78_03005	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
C9I78_03010	ENOG4105HBR	Rna-binding protein
C9I78_03015	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
C9I78_03020	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
C9I78_03025	ENOG4105EEI	dihydropteroate synthase
C9I78_03030	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
C9I78_03055	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
C9I78_03060	ENOG4105CHV	Transcription elongation factor NusA
C9I78_03065	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
C9I78_03070	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
C9I78_03075	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
C9I78_03080	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
C9I78_03085	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
C9I78_03090	ENOG4105RT1	May be involved in cell division (By similarity)
C9I78_03100	ENOG4105C3S	Mate efflux family protein
C9I78_03105	ENOG4106RZ4	Peptidase U32
C9I78_03110	ENOG4105CFP	Peptidase U32
C9I78_03115	ENOG4105BZU	Histidine kinase
C9I78_03120	ENOG4105XPQ	lipid carrier protein
C9I78_03125	ENOG4108YYD	acetyltransferase
C9I78_03145	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
C9I78_03155	ENOG4105EYA	deoxyribonuclease
C9I78_03160	ENOG4105D9N	nucleoside
C9I78_03165	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
C9I78_03170	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
C9I78_03175	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
C9I78_03180	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
C9I78_03190	ENOG4105EAC	phosphoserine phosphatase
C9I78_03200	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
C9I78_03205	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C9I78_03210	ENOG4105ETT	transcriptional Regulator, LysR family
C9I78_03310	ENOG41064T2	transcriptional regulator, lysR family
C9I78_03315	ENOG4105E5D	amino acid
C9I78_03320	ENOG4105FK9	beta-D-galactosidase beta subunit
C9I78_03325	ENOG4105CNT	hydrolase family 2
C9I78_03330	ENOG4105CQ4	Transcriptional regulator
C9I78_03340	ENOG4105CMR	udp-glucose 4-epimerase
C9I78_03345	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
C9I78_03350	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
C9I78_03355	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
C9I78_03360	ENOG4105ETE	Transcriptional regulator (LacI family
C9I78_03370	ENOG4105CT4	transporter
C9I78_03375	ENOG41060NJ	transcriptional regulator
C9I78_03380	ENOG4108Y51	tRNA-binding protein
C9I78_03395	ENOG4107RX3	Mg2 transporter protein cora family protein
C9I78_03400	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
C9I78_03405	ENOG4105E98	transcriptional regulator DeoR family
C9I78_03410	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
C9I78_03415	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C9I78_03430	ENOG4105CXY	transporter
C9I78_03435	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
C9I78_03440	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
C9I78_03445	ENOG4105X2V	dna damage-inducible protein
C9I78_03450	ENOG4105EVZ	LysR family transcriptional regulator
C9I78_03460	ENOG4105E68	Sulfatase
C9I78_03465	ENOG4105DSY	exodeoxyribonuclease V, gamma
C9I78_03475	ENOG4107QKA	exodeoxyribonuclease V beta
C9I78_03480	ENOG4107QYX	exodeoxyribonuclease v alpha
C9I78_03490	ENOG4107QZM	n-acetylglutamate synthase
C9I78_03505	ENOG4105CA3	membrane-bound lytic murein transglycosylase
C9I78_03510	ENOG4105CUZ	uba thif-type nad fad binding protein
C9I78_03515	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
C9I78_03520	ENOG4105BZU	Histidine kinase
C9I78_03525	ENOG4105C9B	Cysteine desulfurase
C9I78_03530	ENOG4107S0N	DJ-1 family
C9I78_03535	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
C9I78_03560	ENOG4105K6V	RNA polymerase
C9I78_03575	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C9I78_03580	ENOG4105IEY	(LipO)protein
C9I78_03585	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
C9I78_03590	ENOG4105M85	Bola protein
C9I78_03600	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C9I78_03605	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C9I78_03610	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C9I78_03615	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C9I78_03620	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
C9I78_03625	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
C9I78_03630	ENOG4105CJ2	(LipO)protein
C9I78_03645	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C9I78_03650	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C9I78_03670	ENOG4105C8J	)-transporter
C9I78_03680	ENOG4105W1I	UPF0253 protein
C9I78_03690	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
C9I78_03695	ENOG4108R96	Methyltransferase, YaeB family
C9I78_03700	ENOG4105NRA	50s ribosomal protein l31 type b
C9I78_03715	ENOG4105CFC	Transporter
C9I78_03720	ENOG4108UPT	UPF0178 protein
C9I78_03745	ENOG4105WP7	tRNA pseudouridine synthase C
C9I78_03750	ENOG4105DR9	pseudouridine synthase
C9I78_03755	ENOG4108T8E	UPF0325 protein
C9I78_03760	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
C9I78_03765	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
C9I78_03770	ENOG4105CE9	30S ribosomal protein S2
C9I78_03775	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
C9I78_03780	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
C9I78_03785	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
C9I78_03790	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
C9I78_03795	ENOG4105KNE	Phosphatidate cytidylyltransferase
C9I78_03800	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
C9I78_03805	ENOG4105DZP	Membrane-associated zinc metalloprotease
C9I78_03815	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
C9I78_03820	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C9I78_03825	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C9I78_03830	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C9I78_03835	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C9I78_03840	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C9I78_03845	ENOG4105C0B	DNA polymerase III (alpha subunit)
C9I78_03850	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
C9I78_03855	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
C9I78_03865	ENOG4108YZA	Nitrogen regulatory protein pii
C9I78_03870	ENOG4107NA1	Endonuclease Exonuclease phosphatase
C9I78_03880	ENOG4105E9H	Lytic Murein transglycosylase
C9I78_03885	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
C9I78_03890	ENOG4105D1A	Methyltransferase
C9I78_03895	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
C9I78_03900	ENOG4107RZZ	dna polymerase iii epsilon subunit
C9I78_03930	ENOG4107QPN	acyl-Coa dehydrogenase
C9I78_03935	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
C9I78_03940	ENOG4105E7A	Glutamine amidotransferase
C9I78_03945	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
C9I78_03950	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
C9I78_03955	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
C9I78_03960	ENOG4105C2W	permease
C9I78_03975	ENOG4105CS1	NAD(P)H quinone oxidoreductase
C9I78_03980	ENOG4105K89	arsenate reductase
C9I78_03985	ENOG4105ERG	peptidase m48, ste24p
C9I78_04000	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C9I78_04005	ENOG4105RH4	Glycine cleavage system transcriptional repressor
C9I78_04015	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C9I78_04030	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C9I78_04035	ENOG4105KUZ	arsenate reductase
C9I78_04060	ENOG4105QZU	Inner membrane protein YfeZ
C9I78_04065	ENOG4105EZR	dyp-type peroxidase family protein
C9I78_04070	ENOG4105I03	Flagellin
C9I78_04080	ENOG4105I03	Flagellin
C9I78_04085	ENOG4105I03	Flagellin
C9I78_04090	ENOG41063QE	flagellar protein FlaG
C9I78_04095	ENOG4107BRV	flagellar capping protein
C9I78_04105	ENOG4105MQ3	flagellar protein FliS
C9I78_04110	ENOG4108JUA	Transcriptional regulator
C9I78_04115	ENOG4105BZU	Histidine kinase
C9I78_04120	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_04125	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
C9I78_04130	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
C9I78_04135	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C9I78_04145	ENOG4108JIR	Flagellum-specific ATP synthase
C9I78_04165	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C9I78_04170	ENOG4105DD5	Flagellar motor switch protein
C9I78_04175	ENOG4105VTB	flagellar biosynthesis protein fliO
C9I78_04180	ENOG4105CN7	Flagellar biosynthetic protein FliP
C9I78_04185	ENOG4105VS8	Flagellar biosynthetic protein fliq
C9I78_04190	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
C9I78_04195	ENOG4105D00	flagellar biosynthetic protein flhB
C9I78_04200	ENOG4105D7B	Flagellar biosynthesis protein flha
C9I78_04205	ENOG4105FZW	flagellar biosynthesis regulator FlhF
C9I78_04210	ENOG4107R21	site-determining protein
C9I78_04215	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C9I78_04220	ENOG4108VYJ	response regulator receiver protein
C9I78_04225	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
C9I78_04230	ENOG4105CBS	Chea signal transduction histidine kinase
C9I78_04235	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C9I78_04240	ENOG4107QJE	Chromosome Partitioning Protein
C9I78_04250	ENOG4108V3W	Chemotaxis protein, CheW
C9I78_04260	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
C9I78_04265	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
C9I78_04270	ENOG41060IM	Heme exporter protein
C9I78_04275	ENOG4105X3C	heme exporter protein
C9I78_04280	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
C9I78_04285	ENOG4105DA4	cytochrome c-type biogenesis protein
C9I78_04290	ENOG4107QX9	Thiol disulfide interChange protein
C9I78_04295	ENOG4108M1T	Cytochrome c-type biogenesis protein
C9I78_04305	ENOG410903C	(LipO)protein
C9I78_04310	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
C9I78_04315	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
C9I78_04335	ENOG4105CHU	acetyl-coa acetyltransferase
C9I78_04340	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C9I78_04350	ENOG4107QXK	peptidase
C9I78_04355	ENOG4108BY2	phosphohistidine phosphatase
C9I78_04360	ENOG4108DG9	Smr protein MutS2
C9I78_04365	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
C9I78_04370	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
C9I78_04375	ENOG4105EN6	Membrane
C9I78_04385	ENOG4108BPE	-transporting atpase
C9I78_04390	ENOG4105MH2	YfcL protein
C9I78_04400	ENOG4105Q8W	reductase
C9I78_04405	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
C9I78_04410	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C9I78_04420	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
C9I78_04425	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C9I78_04435	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
C9I78_04440	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
C9I78_04445	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
C9I78_04450	ENOG4108S3P	Sporulation domain protein
C9I78_04455	ENOG4105E96	Colicin v production protein
C9I78_04460	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
C9I78_04465	ENOG4105EJC	lysr family transcriptional regulator
C9I78_04470	ENOG4105I93	response regulator
C9I78_04480	ENOG4105WD1	Membrane
C9I78_04485	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
C9I78_04490	ENOG4107QMP	dna polymerase iii subunits gamma and tau
C9I78_04495	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
C9I78_04500	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
C9I78_04505	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
C9I78_04510	ENOG4105C44	Serine transporter
C9I78_04515	ENOG4105KME	endoribonuclease L-psp
C9I78_04520	ENOG4105CEM	UPF0597 protein
C9I78_04530	ENOG4105KRS	Proteinase inhibitor
C9I78_04535	ENOG4105Y3U	Transglycosylase-associated protein
C9I78_04540	ENOG4108ZZ3	UPF0260 protein
C9I78_04550	ENOG41067V3	Antibiotic biosynthesis monooxygenase
C9I78_04555	ENOG4108UYE	Lactoylglutathione lyase
C9I78_04565	ENOG4105G6Z	alkaline phosphatase
C9I78_04585	ENOG4105DHI	Methyltransferase
C9I78_04590	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_04595	ENOG4105DSB	aldose 1-epimerase
C9I78_04600	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C9I78_04605	ENOG4105E0X	reductase
C9I78_04615	ENOG4105VUT	cytoplasmic protein
C9I78_04620	ENOG4105HDK	L-asparaginase
C9I78_04625	ENOG4105D07	Signal peptide peptidase, SppA
C9I78_04630	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C9I78_04635	ENOG41069NU	Nitroreductase
C9I78_04640	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C9I78_04655	ENOG4108RU0	short-chain dehydrogenase reductase
C9I78_04660	ENOG4105DGU	Histone deacetylase
C9I78_04670	ENOG4105E68	Sulfatase
C9I78_04675	ENOG4105YDX	UPF0352 protein
C9I78_04680	ENOG4106V8H	Nucleoid-associated protein
C9I78_04695	ENOG4105DFD	Na H antiporter
C9I78_04700	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
C9I78_04705	ENOG4105EYW	Ion transport protein
C9I78_04710	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
C9I78_04715	ENOG4108EKI	Dehydrogenase
C9I78_04730	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C9I78_04735	ENOG4105M2J	Glutaredoxin
C9I78_04745	ENOG4105D3Y	Na H antiporter
C9I78_04750	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
C9I78_04765	ENOG4105EIY	sodium-type flagellar protein motY
C9I78_04770	ENOG4106WH9	Protein of unknown function (DUF2753)
C9I78_04775	ENOG4108UYE	Lactoylglutathione lyase
C9I78_04780	ENOG4105CSM	endonuclease III
C9I78_04785	ENOG4105DZB	Electron transport complex
C9I78_04790	ENOG4108UQQ	Electron transport complex
C9I78_04795	ENOG4105D6A	Electron transport complex
C9I78_04805	ENOG4108R3D	Electron transport complex
C9I78_04810	ENOG4105DGN	Electron transport complex
C9I78_04825	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
C9I78_04830	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_04840	ENOG4105CHW	UPF0052 protein
C9I78_04845	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C9I78_04850	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
C9I78_04855	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
C9I78_04860	ENOG4105M00	molybdopterin converting factor, subunit 1
C9I78_04865	ENOG4108ZAF	Molybdopterin
C9I78_04870	ENOG4107QSI	ABC, transporter
C9I78_04875	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C9I78_04880	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C9I78_04885	ENOG4105C3U	ABC transporter
C9I78_04890	ENOG4108JQ7	(ABC) transporter
C9I78_04895	ENOG4105CHF	Glutathione S-transferase
C9I78_04905	ENOG4107PU6	Membrane
C9I78_04910	ENOG4108DNC	Involved in acetate metabolism (By similarity)
C9I78_04915	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
C9I78_04920	ENOG4105PQ6	UPF0208 membrane protein
C9I78_04930	ENOG4105C7J	ABC transporter, permease
C9I78_04935	ENOG4108JJB	ABC transporter
C9I78_04940	ENOG4107R28	alpha amylase, catalytic region
C9I78_04945	ENOG4105BZU	Histidine kinase
C9I78_04950	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
C9I78_04955	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C9I78_04960	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
C9I78_04965	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C9I78_04970	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
C9I78_04980	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
C9I78_04985	ENOG4105D1F	ATP-binding protein
C9I78_04990	ENOG4105DBI	uridine monophosphokinase
C9I78_05000	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
C9I78_05010	ENOG4105CHH	sulfate transporter
C9I78_05020	ENOG4105C03	ribonuclease
C9I78_05035	ENOG4105EI2	Pseudouridine synthase
C9I78_05040	ENOG4108UHJ	MAF-like protein
C9I78_05045	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
C9I78_05050	ENOG4105VGS	50s ribosomal protein l32
C9I78_05055	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
C9I78_05060	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C9I78_05065	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
C9I78_05070	ENOG4105CHR	reductase
C9I78_05075	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C9I78_05080	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C9I78_05090	ENOG4105HHA	aminodeoxychorismate lyase
C9I78_05095	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
C9I78_05100	ENOG4107QRG	dna polymerase iii
C9I78_05105	ENOG4105F8V	Hydrolase, tatD family
C9I78_05110	ENOG4105CI1	PTS System
C9I78_05130	ENOG4105C8J	)-transporter
C9I78_05145	ENOG4108NRW	Phospholipase, patatin family
C9I78_05150	ENOG4105CA9	Pyruvate kinase
C9I78_05155	ENOG4105DAG	ROK family
C9I78_05160	ENOG4107R88	Chemotaxis protein (CheV)
C9I78_05165	ENOG4105C0B	DNA polymerase III (alpha subunit)
C9I78_05180	ENOG4105UBK	short-chain dehydrogenase reductase
C9I78_05185	ENOG4105ERU	peptidase
C9I78_05190	ENOG4105CAT	Cytidine monophosphate kinase
C9I78_05195	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
C9I78_05200	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C9I78_05205	ENOG4105Q4A	inner membrane protein yciS
C9I78_05210	ENOG4105CFV	Tetratricopeptide repeat protein
C9I78_05215	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
C9I78_05220	ENOG4108J59	Extracellular solute-binding protein, family 5
C9I78_05235	ENOG4105CKK	Glycosyl transferase, family 2
C9I78_05245	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
C9I78_05255	ENOG4105DY2	Paraquat-inducible protein b
C9I78_05260	ENOG4105F1S	paraquat-inducible protein a
C9I78_05265	ENOG4105NQN	cytochrome C
C9I78_05275	ENOG4105DB1	molybdopterin oxidoreductase
C9I78_05280	ENOG4106WHD	Tetrathionate reductase
C9I78_05285	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
C9I78_05290	ENOG4106AFQ	Histidine kinase
C9I78_05295	ENOG4108ZXC	Two component transcriptional regulator, luxr family
C9I78_05300	ENOG4105EXG	Transcriptional regulator
C9I78_05310	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
C9I78_05315	ENOG4105N6Y	Thioredoxin
C9I78_05330	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
C9I78_05345	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
C9I78_05355	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C9I78_05360	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C9I78_05365	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C9I78_05370	ENOG4108W2Y	isochorismatase
C9I78_05375	ENOG41063TF	transcriptional regulator (AraC
C9I78_05385	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
C9I78_05395	ENOG4105J12	Multidrug resistance protein mdtN
C9I78_05400	ENOG4105JQN	Transcriptional regulator
C9I78_05420	ENOG41062D9	Histidine kinase
C9I78_05425	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C9I78_05435	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_05440	ENOG4105CCT	upf0313 protein
C9I78_05460	ENOG4105DZ2	Transcriptional regulator
C9I78_05470	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
C9I78_05480	ENOG4105K9H	YciI-like protein
C9I78_05485	ENOG4105NAU	thioesterase Superfamily protein
C9I78_05490	ENOG4107835	probably involved in intracellular septation (By similarity)
C9I78_05500	ENOG4105BZU	Histidine kinase
C9I78_05510	ENOG4105CK2	sodium dicarboxylate symporter
C9I78_05520	ENOG4105CEY	Amp-dependent synthetase and ligase
C9I78_05525	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
C9I78_05530	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
C9I78_05535	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C9I78_05540	ENOG4105DK0	Indole-3-glycerol phosphate synthase
C9I78_05545	ENOG4108I0Q	anthranilate phosphoribosyltransferase
C9I78_05550	ENOG4105DDQ	anthranilate synthase
C9I78_05555	ENOG4105CRQ	synthase (Component I)
C9I78_05565	ENOG4105DB7	PHP domain protein
C9I78_05570	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
C9I78_05580	ENOG4105FE9	pseudouridine synthase
C9I78_05590	ENOG4108W5H	UPF0263 protein
C9I78_05595	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
C9I78_05605	ENOG4105CQ2	DNA polymerase
C9I78_05610	ENOG4105WH1	Two component transcriptional regulator luxr family
C9I78_05615	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
C9I78_05655	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
C9I78_05680	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C9I78_05685	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
C9I78_05690	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C9I78_05695	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C9I78_05710	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
C9I78_05720	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
C9I78_05725	ENOG4105DVI	reductase, NrfD
C9I78_05730	ENOG4105DA4	cytochrome c-type biogenesis protein
C9I78_05735	ENOG4107QX9	Thiol disulfide interChange protein
C9I78_05740	ENOG4108DMF	Cytochrome C biogenesis protein
C9I78_05750	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
C9I78_05775	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
C9I78_05780	ENOG4105EAQ	(twin-arginine translocation) pathway signal
C9I78_05785	ENOG4105C5X	domain protein
C9I78_05800	ENOG4105CH5	extracellular solute-binding protein, family 7
C9I78_05810	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C9I78_05825	ENOG41067TZ	transcriptional regulator, MarR family
C9I78_05830	ENOG4105C94	Transporter
C9I78_05835	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_05855	ENOG4105CGF	Aromatic amino acid aminotransferase
C9I78_05880	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C9I78_05890	ENOG4105C5S	asparaginyl-tRNA synthetase
C9I78_05895	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_05900	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
C9I78_05910	ENOG4105BZU	Histidine kinase
C9I78_05915	ENOG4105EJQ	L-serine dehydratase
C9I78_05920	ENOG4105C44	Serine transporter
C9I78_05925	ENOG4105P8F	nudix hydrolase
C9I78_05940	ENOG4105CRQ	synthase (Component I)
C9I78_05960	ENOG4105CM6	amino acid regulated cytosolic protein
C9I78_05965	ENOG4106K28	UPF0283 membrane protein
C9I78_05975	ENOG4105D9U	N-acetyltransferase
C9I78_06070	ENOG4105U0R	haloacid dehalogenase-like hydrolase
C9I78_06115	ENOG41067XF	inhibitor
C9I78_06155	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
C9I78_06365	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
C9I78_06450	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
C9I78_06665	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
C9I78_06730	ENOG4107S6Z	Na H antiporter
C9I78_06735	ENOG4105CFQ	glutamine synthetase
C9I78_06745	ENOG4108Z86	Glutamine amidotransferase
C9I78_06750	ENOG4107VRI	Transcriptional regulator
C9I78_06755	ENOG4105C26	Dehydrogenase
C9I78_06760	ENOG4105CJP	fad dependent oxidoreductase
C9I78_06770	ENOG4105DWY	Agmatine deiminase
C9I78_06775	ENOG4105C26	Dehydrogenase
C9I78_06780	ENOG4108JPW	Aminotransferase
C9I78_06785	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
C9I78_06795	ENOG4105BZU	Histidine kinase
C9I78_06820	ENOG4108ZT1	Transcriptional regulator
C9I78_06825	ENOG4105MSB	protein, conserved in bacteria
C9I78_06845	ENOG4108UW5	maltose o-acetyltransferase
C9I78_06860	ENOG4105BZU	Histidine kinase
C9I78_06865	ENOG4105BZU	Histidine kinase
C9I78_06875	ENOG41090FY	type IV pilus biogenesis stability protein PilW
C9I78_06880	ENOG4105CVG	Homoserine O-transsuccinylase
C9I78_06895	ENOG4105E5D	amino acid
C9I78_06905	ENOG4105D1S	lipid A biosynthesis
C9I78_06910	ENOG4105CTD	carboxy-peptidase
C9I78_06915	ENOG410829K	Lysine exporter protein (Lyse ygga)
C9I78_06925	ENOG4105BZG	amino acid carrier protein
C9I78_06950	ENOG4105E0M	Sulfatase
C9I78_06955	ENOG4105DHQ	Histidine kinase
C9I78_06980	ENOG4108IQE	Amp-dependent synthetase and ligase
C9I78_06990	ENOG4105GIJ	Glycine betaine
C9I78_06995	ENOG4108HQS	Glycine betaine
C9I78_07000	ENOG4108IJ7	Glycine betaine
C9I78_07015	ENOG4105C94	Transporter
C9I78_07020	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
C9I78_07025	ENOG4108JPW	Aminotransferase
C9I78_07030	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
C9I78_07035	ENOG4105CZK	Aspartate kinase
C9I78_07050	ENOG4105CA0	peroxidase
C9I78_07065	ENOG4107V40	secretion protein, HlyD family
C9I78_07080	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
C9I78_07085	ENOG4108V9W	transcriptional regulatory protein
C9I78_07090	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
C9I78_07095	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
C9I78_07100	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
C9I78_07115	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
C9I78_07120	ENOG4105C26	Dehydrogenase
C9I78_07140	ENOG4108KB1	transcriptional regulator, arac family
C9I78_07170	ENOG41066XE	Type III export protein
C9I78_07255	ENOG41062JF	Transcriptional regulator
C9I78_07365	ENOG4105EJ9	Membrane
C9I78_07395	ENOG4105CR4	methylisocitrate lyase
C9I78_07400	ENOG4105BZN	citrate synthase
C9I78_07405	ENOG4108I0Z	Aconitate hydratase
C9I78_07410	ENOG4105C7F	AcnD-accessory protein PrpF
C9I78_07415	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C9I78_07420	ENOG4108R6G	acetyltransferase
C9I78_07435	ENOG410667J	hydrolase
C9I78_07440	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
C9I78_07445	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
C9I78_07450	ENOG4105BZU	Histidine kinase
C9I78_07460	ENOG4105CDV	Ompa motb domain protein
C9I78_07475	ENOG4105CDV	Ompa motb domain protein
C9I78_07490	ENOG4105DR4	Methyltransferase
C9I78_07495	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_07500	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
C9I78_07505	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
C9I78_07515	ENOG4108MN8	Membrane
C9I78_07520	ENOG4105CDA	abc transporter atp-binding protein
C9I78_07525	ENOG4105DRP	amino acid AbC transporter
C9I78_07530	ENOG4105EZ7	amino acid ABC transporter
C9I78_07535	ENOG4107QXX	ABC transporter
C9I78_07555	ENOG4108VPT	UPF0234 protein
C9I78_07560	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C9I78_07580	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C9I78_07590	ENOG4105DY2	Paraquat-inducible protein b
C9I78_07595	ENOG4105H2K	paraquat-inducible protein a
C9I78_07600	ENOG4105BZ1	(ABC) transporter
C9I78_07605	ENOG4108ZGC	gaf domain protein
C9I78_07610	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
C9I78_07615	ENOG4105CN1	protease
C9I78_07625	ENOG4105CD8	aminopeptidase N
C9I78_07635	ENOG4105C7I	Dehydrogenase
C9I78_07640	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
C9I78_07645	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
C9I78_07655	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
C9I78_07665	ENOG4105C5H	ABC transporter
C9I78_07680	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
C9I78_07685	ENOG4105DAN	ATP-dependent protease
C9I78_07690	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
C9I78_07725	ENOG4105VZ1	Replication Protein
C9I78_07830	ENOG4105BZU	Histidine kinase
C9I78_07845	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
C9I78_07860	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
C9I78_07870	ENOG4105C59	p-type ATPase
C9I78_07885	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
C9I78_07890	ENOG4105Q9Y	Universal stress protein
C9I78_07900	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
C9I78_07920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C9I78_07925	ENOG4105F38	ABC transporter, permease
C9I78_07930	ENOG4105D38	putrescine abc transporter
C9I78_07935	ENOG4107RUE	extracellular solute-binding protein family 1
C9I78_07940	ENOG4107RUE	extracellular solute-binding protein family 1
C9I78_07945	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
C9I78_08010	ENOG4105QAX	Iron-sulfur
C9I78_08015	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
C9I78_08025	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
C9I78_08050	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C9I78_08055	ENOG4105C5H	ABC transporter
C9I78_08065	ENOG4105BZU	Histidine kinase
C9I78_08070	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_08090	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C9I78_08095	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
C9I78_08100	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C9I78_08110	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
C9I78_08115	ENOG4106IUH	DTW domain containing protein
C9I78_08150	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_08155	ENOG4107TT5	NLP P60 protein
C9I78_08165	ENOG4105BZU	Histidine kinase
C9I78_08170	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
C9I78_08175	ENOG4105FGM	Fructosamine kinase
C9I78_08185	ENOG4108R6K	riboflavin synthase, subunit alpha
C9I78_08190	ENOG4107QI1	Mate efflux family protein
C9I78_08205	ENOG41082AN	stage II sporulation protein
C9I78_08215	ENOG4107V1M	polysaccharide export protein
C9I78_08235	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_08280	ENOG4105CPK	Glycosyl transferase (Group 1
C9I78_08285	ENOG4105CND	Glycosyl transferase, family 2
C9I78_08300	ENOG4105C94	Transporter
C9I78_08315	ENOG4105CQ7	ATP-dependent helicase
C9I78_08320	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
C9I78_08330	ENOG4108NEM	leader-binding protein dmsD
C9I78_08335	ENOG4107KGK	dmso reductase anchor subunit
C9I78_08340	ENOG4105QAX	Iron-sulfur
C9I78_08345	ENOG4107QY8	reductase
C9I78_08375	ENOG4105BZU	Histidine kinase
C9I78_08385	ENOG4105CFG	Acts as a chaperone (By similarity)
C9I78_08390	ENOG4105CFG	Acts as a chaperone (By similarity)
C9I78_08420	ENOG4105BZ1	(ABC) transporter
C9I78_08425	ENOG4105BZ1	(ABC) transporter
C9I78_08450	ENOG4105E0U	tyrosine-specific transport protein
C9I78_08465	ENOG4105DHT	Metal Dependent Phosphohydrolase
C9I78_08560	ENOG4105EW9	transcriptional regulator AsnC family
C9I78_08595	ENOG4105D9P	serine threonine protein kinase
C9I78_08620	ENOG4105CS6	Rhs element vgr protein
C9I78_08625	ENOG4108WC9	type VI secretion system effector, hcp1 family
C9I78_08630	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C9I78_08635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_08640	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C9I78_08660	ENOG4105DR5	peptidase
C9I78_08670	ENOG4105EE5	Membrane protein terC
C9I78_08680	ENOG41076CZ	activating enzyme
C9I78_08685	ENOG4105G0K	glycine radical enzyme YjjI family
C9I78_08695	ENOG4105CPI	Metal Dependent Phosphohydrolase
C9I78_08700	ENOG4105BZU	Histidine kinase
C9I78_08705	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_08710	ENOG4105BZU	Histidine kinase
C9I78_08715	ENOG4105C8P	)-transporter
C9I78_08750	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C9I78_08755	ENOG4105EQ2	LysR family Transcriptional regulator
C9I78_08770	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
C9I78_08775	ENOG4105CXN	decarboxylase
C9I78_08780	ENOG4105CXN	decarboxylase
C9I78_08785	ENOG4105D5Q	Arginine ornithine antiporter
C9I78_08795	ENOG4105D5Q	Arginine ornithine antiporter
C9I78_08810	ENOG4105Y49	secretion protein, HlyD family
C9I78_08825	ENOG4105EGS	Mechanosensitive ion channel
C9I78_08840	ENOG4105DHJ	ABC, transporter
C9I78_08885	ENOG4108RXX	maleylacetoacetate isomerase
C9I78_08895	ENOG4105F1J	Homogentisate 1,2-dioxygenase
C9I78_08900	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
C9I78_08910	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C9I78_08915	ENOG4107QSI	ABC, transporter
C9I78_08920	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C9I78_08925	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C9I78_08930	ENOG4105C3U	ABC transporter
C9I78_08935	ENOG4108JQ7	(ABC) transporter
C9I78_08950	ENOG4107MM9	BNR Asp-box repeat-containing protein
C9I78_08965	ENOG4105D38	putrescine abc transporter
C9I78_08970	ENOG4105F38	ABC transporter, permease
C9I78_08975	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C9I78_08980	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
C9I78_08985	ENOG4105CIF	Ornithine Cyclodeaminase
C9I78_09005	ENOG4105CTU	Proline racemase
C9I78_09035	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
C9I78_09040	ENOG4108VKG	metal-dependent hydrolase
C9I78_09045	ENOG4105KPE	licD family
C9I78_09055	ENOG4107XDJ	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
C9I78_09075	ENOG4107RSM	transcriptional regulator
C9I78_09095	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
C9I78_09100	ENOG4108IU2	vtamin B12-transporter permease
C9I78_09105	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
C9I78_09130	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
C9I78_09135	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
C9I78_09140	ENOG4105K4T	epimerase
C9I78_09145	ENOG4108ETY	sodium dicarboxylate symporter
C9I78_09150	ENOG4105CJB	Exodeoxyribonuclease I
C9I78_09155	ENOG4105VAW	lrga family
C9I78_09160	ENOG41067MG	lrgb family
C9I78_09165	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
C9I78_09170	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
C9I78_09175	ENOG4105FQ6	thiopurine methyltransferase
C9I78_09185	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
C9I78_09200	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
C9I78_09205	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
C9I78_09210	ENOG4105BZU	Histidine kinase
C9I78_09240	ENOG4105K8R	UPF0145 protein
C9I78_09245	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
C9I78_09250	ENOG41082NX	50s ribosomal protein l35
C9I78_09255	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
C9I78_09260	ENOG4105C22	threonyL-tRNA synthetase
C9I78_09275	ENOG4105CZE	histidine utilization repressor
C9I78_09280	ENOG4105CI2	imidazolone-5-propionate hydrolase
C9I78_09285	ENOG41088SP	formiminoglutamate hydrolase
C9I78_09295	ENOG4105C84	Histidine ammonia-lyase
C9I78_09310	ENOG4105CQB	FAD linked oxidase domain protein
C9I78_09325	ENOG4105CDV	Ompa motb domain protein
C9I78_09345	ENOG4105C8V	SAICAR synthetase
C9I78_09360	ENOG4105HDD	phospholipase
C9I78_09365	ENOG4105CQ7	ATP-dependent helicase
C9I78_09370	ENOG4107R1I	NAD-dependent malic enzyme
C9I78_09375	ENOG4107GZ4	SanA protein
C9I78_09380	ENOG4105C8P	)-transporter
C9I78_09385	ENOG4105BZU	Histidine kinase
C9I78_09405	ENOG4105C3M	thioredoxin reductase
C9I78_09410	ENOG4108JJ9	ABC, transporter
C9I78_09415	ENOG4108JJ8	(ABC) transporter
C9I78_09420	ENOG4105BZC	d-serine deaminase
C9I78_09425	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
C9I78_09435	ENOG4105BZU	Histidine kinase
C9I78_09470	ENOG4105DWU	Membrane
C9I78_09480	ENOG4105DY8	decarboxylase
C9I78_09485	ENOG4106KNT	transcriptional regulator
C9I78_09500	ENOG41090BQ	Glutaredoxin
C9I78_09505	ENOG4105D0C	transport protein
C9I78_09510	ENOG4105RKW	reductase (By
C9I78_09515	ENOG4107QPN	acyl-Coa dehydrogenase
C9I78_09520	ENOG41067SE	Tetr family transcriptional regulator
C9I78_09525	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C9I78_09540	ENOG4108I0Y	(ABC) transporter
C9I78_09545	ENOG4107QI1	Mate efflux family protein
C9I78_09550	ENOG4105CGD	Nad-dependent epimerase dehydratase
C9I78_09555	ENOG4105CUW	cytochrome C-TYPE protein
C9I78_09585	ENOG4105C2C	drug resistance transporter, Bcr CflA
C9I78_09590	ENOG4105I08	Pseudouridine synthase
C9I78_09595	ENOG4105CFI	type iii restriction protein res subunit
C9I78_09605	ENOG4105ETX	regulatoR
C9I78_09610	ENOG4105EB3	Histidine kinase
C9I78_09615	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
C9I78_09630	ENOG4105CGH	5'-nucleotidase
C9I78_09645	ENOG4105XZD	Fe-S protein
C9I78_09655	ENOG4108ZXC	Two component transcriptional regulator, luxr family
C9I78_09660	ENOG4106AFQ	Histidine kinase
C9I78_09670	ENOG4105BZ8	glutamate synthase
C9I78_09680	ENOG4108RSN	SNARE associated Golgi
C9I78_09685	ENOG4105VNH	ABC transporter solute-binding protein
C9I78_09690	ENOG4105CXZ	ABC transporter, permease
C9I78_09695	ENOG4108VGW	abc transporter atp-binding protein
C9I78_09700	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
C9I78_09715	ENOG4108JUA	Transcriptional regulator
C9I78_09720	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
C9I78_09725	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
C9I78_09735	ENOG4108W1A	pseudouridine synthase
C9I78_09745	ENOG4105C8J	)-transporter
C9I78_09750	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
C9I78_09755	ENOG4105C28	cystathionine
C9I78_09760	ENOG4107IFA	Lipase (EC 3.1.1.3)
C9I78_09770	ENOG4108R3E	Dna-3-methyladenine glycosylase i
C9I78_09785	ENOG410624X	efflux transporter, rnd family, mfp subunit
C9I78_09790	ENOG4105FM1	phage shock protein C
C9I78_09795	ENOG4105YYT	phage shock protein B
C9I78_09800	ENOG41087YS	Phage shock protein A
C9I78_09805	ENOG4105E51	psp operon transcriptional activator
C9I78_09810	ENOG4108J59	Extracellular solute-binding protein, family 5
C9I78_09815	ENOG4108I5W	peptide transport system, permease protein
C9I78_09820	ENOG4108EU3	peptide transport system, permease
C9I78_09825	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
C9I78_09830	ENOG4108JQ2	peptide transport system atp-binding protein
C9I78_09840	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
C9I78_09855	ENOG4108J2R	molybdopterin oxidoreductase
C9I78_09870	ENOG4105C4B	ABC transporter, permease
C9I78_09880	ENOG4105TMB	Formate nitrite transporter
C9I78_09905	ENOG4105GFG	DUF218 domain
C9I78_09910	ENOG4107104	thymidine kinase
C9I78_09915	ENOG4105C8N	cysteinyl-tRNA synthetase
C9I78_09920	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C9I78_09925	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
C9I78_09930	ENOG4105D58	Diguanylate phosphodiesterase
C9I78_09940	ENOG4105K5B	UPF0225 protein
C9I78_09945	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
C9I78_09950	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
C9I78_09960	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
C9I78_09965	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
C9I78_09970	ENOG4105CIH	Imidazole acetol-phosphate transaminase
C9I78_09975	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
C9I78_09980	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
C9I78_09985	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_09995	ENOG4107S6Z	Na H antiporter
C9I78_10000	ENOG4108YX2	DNA-binding protein
C9I78_10005	ENOG4107RE1	Inosine-guanosine kinase
C9I78_10015	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
C9I78_10020	ENOG41075W9	High frequency lysogenization protein HflD homolog
C9I78_10025	ENOG4107QTF	adenylosuccinate lyase
C9I78_10050	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
C9I78_10065	ENOG4107FW0	short-chain dehydrogenase reductase
C9I78_10075	ENOG4105D0M	Protease HtpX homolog
C9I78_10085	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
C9I78_10095	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C9I78_10100	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
C9I78_10105	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C9I78_10110	ENOG4105KSC	Transcriptional regulator, TraR DksA family
C9I78_10125	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
C9I78_10130	ENOG4105D1H	recombination factor protein RarA
C9I78_10135	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
C9I78_10140	ENOG4105CNU	cell division protein FtsK
C9I78_10145	ENOG4105EW9	transcriptional regulator AsnC family
C9I78_10150	ENOG4105DCF	alanine dehydrogenase
C9I78_10160	ENOG4107R11	Transcriptional regulator
C9I78_10170	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
C9I78_10205	ENOG4105BZS	acriflavin resistance protein
C9I78_10210	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
C9I78_10225	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_10275	ENOG4108RNS	Exports L-alanine (By similarity)
C9I78_10280	ENOG4105BZU	Histidine kinase
C9I78_10290	ENOG4106032	Glutathionylspermidine synthase
C9I78_10300	ENOG4105Z6B	inner membrane protein yjfl
C9I78_10310	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
C9I78_10315	ENOG4105UFD	tol-pal system protein YbgF
C9I78_10320	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C9I78_10325	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
C9I78_10335	ENOG4105M8F	Biopolymer transport protein exbD tolR
C9I78_10340	ENOG4105E02	MotA TolQ exbB proton channel
C9I78_10345	ENOG4107YD3	Thioesterase
C9I78_10360	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C9I78_10365	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C9I78_10370	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
C9I78_10375	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
C9I78_10380	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_10385	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
C9I78_10390	ENOG4105C9M	aspartyl-trna synthetase
C9I78_10395	ENOG41081XQ	Conserved Protein
C9I78_10400	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
C9I78_10405	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
C9I78_10415	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
C9I78_10425	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
C9I78_10435	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
C9I78_10440	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
C9I78_10445	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
C9I78_10450	ENOG4106371	Methyltransferase
C9I78_10455	ENOG4107S90	membrAne
C9I78_10460	ENOG4106WF9	DNA-binding transcriptional regulator TorR
C9I78_10465	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
C9I78_10470	ENOG4105ETE	Transcriptional regulator (LacI family
C9I78_10475	ENOG4105HP8	regulator of competence-specific genes
C9I78_10495	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
C9I78_10500	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C9I78_10510	ENOG4105RKX	Protein of unknown function (DUF2498)
C9I78_10515	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
C9I78_10525	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
C9I78_10530	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
C9I78_10535	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
C9I78_10545	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C9I78_10550	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
C9I78_10555	ENOG4105VEQ	Cold shock protein
C9I78_10565	ENOG4108R99	pseudouridine synthase
C9I78_10580	ENOG4105DVT	helicase
C9I78_10585	ENOG4105EJ9	Membrane
C9I78_10590	ENOG4108URS	primosomal replication protein n''
C9I78_10595	ENOG4106428	Protein of unknown function (DUF2496)
C9I78_10600	ENOG4105CGK	Exodeoxyribonuclease III
C9I78_10615	ENOG4105DSP	amino acid AbC transporter
C9I78_10620	ENOG4105E89	ABC transporter
C9I78_10625	ENOG4108JEH	abc transporter atp-binding protein
C9I78_10645	ENOG4105C6N	Formate acetyltransferase
C9I78_10655	ENOG4105F1A	Pyruvate formate-lyase
C9I78_10665	ENOG4105XWI	UPF0304 protein
C9I78_10675	ENOG4105CYN	Serine protein kinase
C9I78_10680	ENOG4106AKX	UPF0229 protein
C9I78_10685	ENOG4105ED1	spovr family
C9I78_10690	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
C9I78_10695	ENOG4105W49	UPF0434 protein
C9I78_10700	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
C9I78_10705	ENOG4105BZ1	(ABC) transporter
C9I78_10710	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
C9I78_10720	ENOG4105D60	lipoprotein releasing system transmembrane protein
C9I78_10725	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C9I78_10730	ENOG4105D60	lipoprotein releasing system transmembrane protein
C9I78_10740	ENOG4108JA2	transcriptioN-repair coupling factor
C9I78_10755	ENOG4105CEP	NADH dehydrogenase
C9I78_10765	ENOG4105D0Y	UPF0227 protein
C9I78_10790	ENOG4105K59	histidine triad (HIT) protein
C9I78_10795	ENOG4108NVR	Methyl-accepting chemotaxis
C9I78_10810	ENOG4107SXA	Phosphorylase
C9I78_10820	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C9I78_10830	ENOG4105DZ0	fad dependent oxidoreductase
C9I78_10835	ENOG4108Z4U	Ferredoxin
C9I78_10850	ENOG4108KHX	Diguanylate cyclase
C9I78_10865	ENOG4108MNP	Glycoprotein polysaccharide metabolism
C9I78_10870	ENOG4105C29	acyl-CoA thioesterase
C9I78_10880	ENOG4108XM1	transcriptional regulator AsnC family
C9I78_10910	ENOG4105BZS	acriflavin resistance protein
C9I78_10915	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C9I78_10960	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
C9I78_10965	ENOG4105HMI	Membrane
C9I78_10975	ENOG4105CEY	Amp-dependent synthetase and ligase
C9I78_10980	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
C9I78_10985	ENOG4108IPT	Naphthoate synthase
C9I78_10990	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
C9I78_10995	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
C9I78_11000	ENOG4105E4F	Isochorismate synthase
C9I78_11005	ENOG4105CHM	Aminotransferase
C9I78_11010	ENOG4105DK2	UPF0207 protein
C9I78_11015	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
C9I78_11030	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
C9I78_11035	ENOG4105EIN	peptidylprolyl cis-trans isomerase
C9I78_11040	ENOG4105K70	DNA-binding protein
C9I78_11045	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
C9I78_11050	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
C9I78_11055	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
C9I78_11060	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
C9I78_11065	ENOG4105CQZ	Histidine kinase
C9I78_11080	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C9I78_11085	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
C9I78_11090	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C9I78_11095	ENOG4105CNG	UPF0061 protein
C9I78_11120	ENOG4107ZYR	domain protein
C9I78_11125	ENOG4105C1J	atp-dependent rna helicase
C9I78_11165	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
C9I78_11190	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
C9I78_11195	ENOG4105C84	Histidine ammonia-lyase
C9I78_11220	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C9I78_11225	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
C9I78_11230	ENOG4105C2D	reductase
C9I78_11235	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
C9I78_11250	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
C9I78_11255	ENOG4105D9N	nucleoside
C9I78_11260	ENOG4105CC0	LysR family Transcriptional regulator
C9I78_11265	ENOG4105CVE	Lytic murein transglycosylase
C9I78_11270	ENOG4105VNG	YcgL domain-containing protein
C9I78_11275	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
C9I78_11280	ENOG4107QMS	site-determining protein
C9I78_11285	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
C9I78_11290	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
C9I78_11295	ENOG4105CEY	Amp-dependent synthetase and ligase
C9I78_11300	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C9I78_11315	ENOG41072GX	Peptidase M22 Glycoprotease
C9I78_11320	ENOG4105DVT	helicase
C9I78_11325	ENOG4105CIY	formyltetrahydrofolate deformylase
C9I78_11330	ENOG4106ZCM	YecM protein
C9I78_11340	ENOG4105C75	arginyL-tRNA synthetase
C9I78_11355	ENOG4105CE1	Ferrous iron transport protein b
C9I78_11360	ENOG4105XFK	Ferrous iron transport protein A
C9I78_11375	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
C9I78_11380	ENOG4105NXV	High-affinity zinc uptake system protein
C9I78_11385	ENOG4105FDK	ABC transporter
C9I78_11390	ENOG4105FAV	ABC, transporter
C9I78_11395	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
C9I78_11400	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
C9I78_11405	ENOG4105C7S	Dehydrogenase
C9I78_11410	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
C9I78_11415	ENOG4105E33	succinate dehydrogenase
C9I78_11420	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
C9I78_11425	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
C9I78_11430	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
C9I78_11435	ENOG4105BZN	citrate synthase
C9I78_11440	ENOG4107QNR	UPF0135 protein
C9I78_11450	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
C9I78_11455	ENOG4107CDU	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (By similarity)
C9I78_11460	ENOG4105EV9	Alpha Beta Hydrolase
C9I78_11470	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
C9I78_11475	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
C9I78_11480	ENOG41090R7	Ferric uptake
C9I78_11485	ENOG4105CX6	glutaminyL-tRNA synthetase
C9I78_11490	ENOG4105CI1	PTS System
C9I78_11500	ENOG4105CE4	GlcNAc 6-P deacetylase
C9I78_11505	ENOG4105E2R	ROK family
C9I78_11510	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C9I78_11515	ENOG4105CAQ	asparagine synthetase
C9I78_11520	ENOG4105MDZ	Transcriptional activator rfaH
C9I78_11525	ENOG4105DUX	Transporter
C9I78_11530	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
C9I78_11535	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
C9I78_11540	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
C9I78_11545	ENOG4108DQ1	activator toxR
C9I78_11565	ENOG4108RE9	Phosphodiesterase
C9I78_11595	ENOG4105ECP	epimerase
C9I78_11600	ENOG4105E1F	short-chain dehydrogenase reductase
C9I78_11610	ENOG4107QR8	Thioredoxin
C9I78_11615	ENOG4107QX8	SPFH domain, Band 7 family protein
C9I78_11645	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C9I78_11650	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
C9I78_11655	ENOG4105EXN	Sulfate transport protein CysZ
C9I78_11660	ENOG4105C6T	cysteine synthase
C9I78_11670	ENOG4105KZ7	phosphocarrier protein hpr
C9I78_11675	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
C9I78_11680	ENOG4105C5Y	PTS System
C9I78_11695	ENOG4105I03	Flagellin
C9I78_11705	ENOG4105I03	Flagellin
C9I78_11715	ENOG4105DTJ	flagellar hook-associated protein
C9I78_11725	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
C9I78_11730	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C9I78_11735	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C9I78_11740	ENOG4105CGA	flagellar basal-body rod protein FlgG
C9I78_11745	ENOG4108KPB	Flagellar basal-body rod protein FlgF
C9I78_11755	ENOG4105BZE	flagellar hook protein, FlgE
C9I78_11760	ENOG4105W00	Flagellar hook capping protein
C9I78_11765	ENOG4108ZC9	flagellar basal-body rod protein flgc
C9I78_11770	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
C9I78_11775	ENOG4105BZU	Histidine kinase
C9I78_11780	ENOG4107R88	Chemotaxis protein (CheV)
C9I78_11830	ENOG4105UYK	outer membrane protein a
C9I78_11840	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
C9I78_11850	ENOG41081QG	Porin Gram-negative type
C9I78_11860	ENOG4105C59	p-type ATPase
C9I78_11875	ENOG4105E2D	ec 3.2.1.52
C9I78_11900	ENOG4108DG9	Smr protein MutS2
C9I78_11905	ENOG4105FE9	pseudouridine synthase
C9I78_11910	ENOG4108Z66	YbaK ebsC protein
C9I78_11915	ENOG4105CGH	5'-nucleotidase
C9I78_11920	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
C9I78_11925	ENOG41063JG	Transcriptional regulator
C9I78_11930	ENOG4108YY7	Invasion gene expression up-regulator SirB
C9I78_11935	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
C9I78_11940	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
C9I78_11945	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
C9I78_11950	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
C9I78_11955	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
C9I78_11960	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
C9I78_11965	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
C9I78_11970	ENOG4105C3G	gtp-binding protein
C9I78_12085	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
C9I78_12095	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
C9I78_12100	ENOG4105C9A	Phoh family
C9I78_12105	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
C9I78_12110	ENOG4108JU5	Magnesium and cobalt efflux protein
C9I78_12115	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
C9I78_12120	ENOG4107PAI	alpha helical protein
C9I78_12125	ENOG4105C8T	Leucyl-tRNA synthetase
C9I78_12130	ENOG4108U2H	Rare lipoprotein B
C9I78_12135	ENOG4105DJF	DNA polymerase III, delta' subunit
C9I78_12140	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
C9I78_12145	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
C9I78_12150	ENOG4105CJN	penicillin-binding protein
C9I78_12155	ENOG4105CNI	cell division protein FtsW
C9I78_12160	ENOG4105K6T	rare lipoprotein A
C9I78_12165	ENOG4105DZ1	carboxypeptidase
C9I78_12170	ENOG4108Z43	UPF0250 protein
C9I78_12175	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
C9I78_12180	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
C9I78_12185	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C9I78_12190	ENOG4108JYZ	YitT family
C9I78_12205	ENOG4105CG3	alpha amylase, catalytic region
C9I78_12210	ENOG4105C5Y	PTS System
C9I78_12215	ENOG4105D4X	repressor
C9I78_12220	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
C9I78_12230	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
C9I78_12235	ENOG4108UMI	ABC transporter, permease
C9I78_12240	ENOG4105D01	(LipO)protein
C9I78_12245	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
C9I78_12250	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
C9I78_12255	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
C9I78_12265	ENOG4105BZU	Histidine kinase
C9I78_12270	ENOG4105EWT	decarboxylase family
C9I78_12275	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
C9I78_12285	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
C9I78_12290	ENOG4105M08	Membrane
C9I78_12300	ENOG4105ETT	transcriptional Regulator, LysR family
C9I78_12305	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
C9I78_12310	ENOG4107QKZ	Ompa motb domain protein
C9I78_12315	ENOG4105E14	MotA TolQ exbB proton channel
C9I78_12320	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C9I78_12325	ENOG4105CTB	Polyprenyl synthetase
C9I78_12330	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
C9I78_12335	ENOG4108ZAI	phosphatidylglycerophosphatase a
C9I78_12340	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
C9I78_12345	ENOG4107YIM	Involved in the transcription termination process (By similarity)
C9I78_12350	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
C9I78_12365	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C9I78_12370	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
C9I78_12375	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
C9I78_12380	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
C9I78_12385	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
C9I78_12390	ENOG4108DJV	Fermentation respiration switch protein
C9I78_12395	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
C9I78_12400	ENOG4105C7N	Xanthine uracil vitamin C permease
C9I78_12405	ENOG4105CIN	aminoacyl-histidine dipeptidase
C9I78_12430	ENOG4108ETH	Formylglycinamide ribotide synthetase
C9I78_12435	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
C9I78_12445	ENOG4108Z6B	deaminase
C9I78_12450	ENOG4105CFC	Transporter
C9I78_12490	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C9I78_12495	ENOG4105CFG	Acts as a chaperone (By similarity)
C9I78_12505	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C9I78_12510	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
C9I78_12520	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
C9I78_12525	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C9I78_12530	ENOG4105VDB	UPF0125 protein
C9I78_12535	ENOG4108Z1B	Cyclase dehydrase
C9I78_12540	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
C9I78_12550	ENOG4105DFP	Integrase
C9I78_12610	ENOG4107QTH	restriction modification system DNA specificity domain
C9I78_12650	ENOG4105BZU	Histidine kinase
C9I78_12700	ENOG4105ETT	transcriptional Regulator, LysR family
C9I78_12705	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
C9I78_12725	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
C9I78_12730	ENOG4108IQK	o-acetylhomoserine
C9I78_12760	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
C9I78_12765	ENOG4105BZG	amino acid carrier protein
C9I78_12775	ENOG4106HK8	GPR1 FUN34 yaaH family protein
C9I78_12785	ENOG4107S6Z	Na H antiporter
C9I78_12865	ENOG4105DFP	Integrase
C9I78_12870	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
C9I78_12875	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C9I78_12880	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
C9I78_12895	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
C9I78_12900	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
C9I78_12905	ENOG4105N21	Membrane
C9I78_12910	ENOG4105CUT	histidyl-tRNA synthetase
C9I78_12915	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
C9I78_12930	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
C9I78_12935	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
C9I78_12940	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
C9I78_12945	ENOG4105WVQ	Fe-S assembly protein IscX
C9I78_12950	ENOG4108ZIT	Ferredoxin, 2FE-2S
C9I78_12955	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
C9I78_12960	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
C9I78_12965	ENOG4108Z4V	iron-sulfur cluster assembly
C9I78_12970	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
C9I78_12975	ENOG4105C3J	Cysteine desulfurase
C9I78_12980	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
C9I78_12985	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
C9I78_12990	ENOG4105ECY	inositol monophosphatase
C9I78_13000	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C9I78_13005	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C9I78_13010	ENOG4105VIE	preprotein translocase, subunit YajC
C9I78_13015	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
C9I78_13020	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
C9I78_13035	ENOG4105W87	Cbs domain
C9I78_13040	ENOG4108I9X	Isocitrate lyase
C9I78_13045	ENOG4107QP3	malate synthase g
C9I78_13055	ENOG4105C5Q	Transcriptional regulator
C9I78_13060	ENOG4105D3R	alkyl hydroperoxide reductase
C9I78_13070	ENOG4106N3A	copper homeostasis protein cutc
C9I78_13075	ENOG4105CSR	polyphosphate kinase 2
C9I78_13085	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C9I78_13090	ENOG4105E2Z	phosphate ABC transporter (Permease
C9I78_13095	ENOG4105C8U	phosphate abc transporter
C9I78_13100	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
C9I78_13105	ENOG4105C9X	ppx gppa phosphatase
C9I78_13115	ENOG4105BZU	Histidine kinase
C9I78_13120	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C9I78_13130	ENOG4105DH7	May be involved in recombination (By similarity)
C9I78_13135	ENOG4105CFP	Peptidase U32
C9I78_13140	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
C9I78_13200	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C9I78_13205	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
C9I78_13210	ENOG4105C34	Pseudouridine synthase
C9I78_13215	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9I78_13220	ENOG4105E4C	Lytic transglycosylase catalytic
C9I78_13225	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
C9I78_13235	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
C9I78_13240	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
C9I78_13245	ENOG4107SC1	transglycosylase
C9I78_13250	ENOG4105C5H	ABC transporter
C9I78_13265	ENOG4105DR5	peptidase
C9I78_13270	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
C9I78_13275	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C9I78_13280	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
C9I78_13285	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
C9I78_13290	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C9I78_13310	ENOG4108HRK	Histidine kinase
C9I78_13315	ENOG4108NEV	two component transcriptional regulator, LytTR family
C9I78_13320	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
C9I78_13325	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
C9I78_13330	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
C9I78_13335	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C9I78_13340	ENOG4105DTN	riboflavin biosynthesis protein ribF
C9I78_13345	ENOG4105CJR	Integral membrane protein (MviN
C9I78_13350	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
C9I78_13360	ENOG41080HT	Transcriptional regulator, arsr family
C9I78_13370	ENOG41063Z6	transcriptional regulator, lysR family
C9I78_13385	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
C9I78_13390	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
C9I78_13395	ENOG4105HF0	Membrane
C9I78_13400	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
C9I78_13405	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
C9I78_13415	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
C9I78_13425	ENOG4105CPC	Aldo Keto reductase
C9I78_13435	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_13440	ENOG4105CRK	lysyL-tRNA synthetase
C9I78_13450	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
C9I78_13455	ENOG4105T95	Thiol disulfide interChange protein
C9I78_13460	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C9I78_13465	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
C9I78_13470	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
C9I78_13475	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
C9I78_13480	ENOG4105C1J	atp-dependent rna helicase
C9I78_13485	ENOG4105D1Q	UPF0246 protein
C9I78_13490	ENOG4105BZG	amino acid carrier protein
C9I78_13505	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
C9I78_13515	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
C9I78_13520	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
C9I78_13525	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
C9I78_13575	ENOG4105D98	threonine synthase
C9I78_13580	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
C9I78_13595	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
C9I78_13610	ENOG41065U4	response regulator
C9I78_13620	ENOG4105BZU	Histidine kinase
C9I78_13630	ENOG4105N5T	Radical SAM Protein
C9I78_13645	ENOG4105CBC	glutamate synthase
C9I78_13650	ENOG4105BZ8	glutamate synthase
C9I78_13660	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
C9I78_13665	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
C9I78_13670	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
C9I78_13675	ENOG4105EN6	Membrane
C9I78_13680	ENOG4105VP0	transcriptional regulator, lysR family
C9I78_13685	ENOG4105EJ9	Membrane
C9I78_13700	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
C9I78_13705	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
C9I78_13710	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
C9I78_13715	ENOG4105M6F	mutator MutT protein
C9I78_13720	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
C9I78_13730	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
C9I78_13735	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
C9I78_13740	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
C9I78_13745	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
C9I78_13750	ENOG4105DFU	Cell wall formation (By similarity)
C9I78_13755	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
C9I78_13765	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
C9I78_13770	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
C9I78_13775	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
C9I78_13780	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
C9I78_13785	ENOG4105CJN	penicillin-binding protein
C9I78_13790	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
C9I78_13795	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
C9I78_13810	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
C9I78_13820	ENOG41082RQ	UPF0102 protein
C9I78_13825	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
C9I78_13830	ENOG4105W4M	Transport-associated protein
C9I78_13835	ENOG4105KB2	stringent starvation protein b
C9I78_13840	ENOG4107MKT	Stringent starvation protein a
C9I78_13845	ENOG4105EIX	cytochrome c1
C9I78_13850	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C9I78_13855	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
C9I78_13860	ENOG4108UJD	30S ribosomal protein S9
C9I78_13865	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
C9I78_13875	ENOG4105D6Z	AFG1 family ATPase
C9I78_13885	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
C9I78_13890	ENOG4105C0H	protease
C9I78_13895	ENOG4105C0H	protease
C9I78_13900	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C9I78_13905	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C9I78_13910	ENOG4105IPS	esterase
C9I78_13915	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
C9I78_13920	ENOG4108SX3	cytoplasmic protein
C9I78_13925	ENOG41087AY	ADP-Ribose pyrophosphatase
C9I78_13930	ENOG4105DFG	type I secretion outer membrane protein
C9I78_13935	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
C9I78_13940	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
C9I78_13945	ENOG4108NVR	Methyl-accepting chemotaxis
C9I78_13955	ENOG4105I7R	Adenylate cyclase
C9I78_13960	ENOG4107IX6	phosphate transport regulator
C9I78_13965	ENOG4105CJ3	phosphate transporter
C9I78_13970	ENOG4106MWK	domain protein
C9I78_13985	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
C9I78_13990	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
C9I78_13995	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C9I78_14000	ENOG4107ZVW	dihydroneopterin aldolase
C9I78_14005	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
C9I78_14010	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
C9I78_14015	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C9I78_14020	ENOG4105VCC	30S ribosomal protein S21
C9I78_14025	ENOG4105KTH	gatB Yqey
C9I78_14030	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
C9I78_14035	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C9I78_14080	ENOG4105I03	Flagellin
C9I78_14090	ENOG4105I03	Flagellin
C9I78_14105	ENOG4105CAF	HipA N-terminal domain protein
C9I78_14115	ENOG4105BZU	Histidine kinase
C9I78_14165	ENOG4107QTH	restriction modification system DNA specificity domain
C9I78_14190	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
C9I78_14200	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C9I78_14210	ENOG4105BZU	Histidine kinase
C9I78_14245	ENOG4105D01	(LipO)protein
C9I78_14290	ENOG4105CTS	PTS system mannitol-specific
C9I78_14295	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
C9I78_14300	ENOG4105E61	Mannitol repressor protein
C9I78_14315	ENOG4108UTZ	Dihydroxyacetone kinase
C9I78_14320	ENOG4105CMT	Dihydroxyacetone kinase
C9I78_14330	ENOG4105GR3	Histidine kinase
C9I78_14345	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
C9I78_14350	ENOG410804X	Transcriptional regulator
C9I78_14360	ENOG4105CA9	Pyruvate kinase
C9I78_14370	ENOG4105BZU	Histidine kinase
C9I78_14375	ENOG4108ZP8	Acetolactate synthase small subunit
C9I78_14380	ENOG4105C7K	acetolactate synthase
C9I78_14385	ENOG4108IQE	Amp-dependent synthetase and ligase
C9I78_14390	ENOG41064T2	transcriptional regulator, lysR family
C9I78_14410	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
C9I78_14415	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
C9I78_14420	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C9I78_14425	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
C9I78_14435	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
C9I78_14440	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
C9I78_14445	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
C9I78_14450	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
C9I78_14455	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
C9I78_14460	ENOG4105NWN	ApaG protein
C9I78_14465	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
C9I78_14480	ENOG4105DWK	Membrane
C9I78_14485	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C9I78_14490	ENOG4105K46	50S ribosomal protein l27
C9I78_14495	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
C9I78_14500	ENOG4105EAH	synthase
C9I78_14510	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C9I78_14515	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
C9I78_14545	ENOG4107T0D	ABC, transporter
C9I78_14550	ENOG4106SMU	thiamine transporter membrane protein
C9I78_14555	ENOG4105DP9	ABC transporter
C9I78_14560	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
C9I78_14565	ENOG4105DFU	Cell wall formation (By similarity)
C9I78_14575	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C9I78_14580	ENOG4105F0N	pyrophosphate phospho-hydrolase
C9I78_14590	ENOG41066HZ	AIG2-like family
C9I78_14595	ENOG4105MA0	exported protein
C9I78_14600	ENOG4105CFU	surface antigen
C9I78_14605	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C9I78_14610	ENOG41061GZ	Protein of unknown function (DUF1107)
C9I78_14615	ENOG4108UUE	Transcriptional regulator
C9I78_14630	ENOG4108I0Y	(ABC) transporter
C9I78_14650	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
C9I78_14665	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
C9I78_14670	ENOG4105C11	sulfate adenylyltransferase), subunit 2
C9I78_14675	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C9I78_14680	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
C9I78_14690	ENOG4105C1J	atp-dependent rna helicase
C9I78_14695	ENOG4107YB6	acetyltransferase, (GNAT) family
C9I78_14705	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C9I78_14715	ENOG4108ZT0	50S ribosomal protein l17
C9I78_14720	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
C9I78_14725	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
C9I78_14730	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
C9I78_14735	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C9I78_14745	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
C9I78_14750	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
C9I78_14755	ENOG4105VPB	50S ribosomal protein L30
C9I78_14760	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
C9I78_14770	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
C9I78_14775	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
C9I78_14780	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
C9I78_14785	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C9I78_14790	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
C9I78_14795	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
C9I78_14800	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
C9I78_14805	ENOG41083MP	50s ribosomal protein l29
C9I78_14810	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
C9I78_14815	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
C9I78_14820	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
C9I78_14825	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
C9I78_14830	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C9I78_14835	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
C9I78_14840	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
C9I78_14845	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
C9I78_14850	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
C9I78_14855	ENOG4105VFB	Binds the 23S rRNA (By similarity)
C9I78_14865	ENOG4105C25	Primosomal protein n'
C9I78_14870	ENOG4105ETE	Transcriptional regulator (LacI family
C9I78_14880	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
C9I78_14885	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
C9I78_14890	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
C9I78_14895	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
C9I78_14900	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
C9I78_14910	ENOG4105CBT	Fructose-1,6-bisphosphatase
C9I78_14935	ENOG4105CP7	Triose-phosphate isomerase
C9I78_14940	ENOG4105CY0	Metallo-Beta-Lactamase
C9I78_14945	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
C9I78_14970	ENOG4108I69	Glycosyl transferases group 1
C9I78_14995	ENOG4108QY5	Ferric enterobactin transport protein
C9I78_15025	ENOG4105E3R	(LipO)protein
C9I78_15030	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
C9I78_15035	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
C9I78_15045	ENOG4105XA0	heptosyltransferase ii
C9I78_15050	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
C9I78_15065	ENOG4105CAQ	asparagine synthetase
C9I78_15070	ENOG4105D3Q	Sugar transferase
C9I78_15080	ENOG4105CJR	Integral membrane protein (MviN
C9I78_15090	ENOG4105F0R	Cytidylyltransferase
C9I78_15095	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
C9I78_15100	ENOG41080IJ	Diacylglycerol kinase
C9I78_15105	ENOG4105DKP	glycosyl transferase, family 9
C9I78_15110	ENOG4106WTF	Glycosyl transferase, family 2
C9I78_15120	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
C9I78_15125	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
C9I78_15130	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
C9I78_15140	ENOG4108I6E	Sulfatase
C9I78_15150	ENOG4105KDC	50s ribosomal protein l28
C9I78_15155	ENOG4105W5Q	DNA repair protein (RadC
C9I78_15160	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_15170	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
C9I78_15175	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
C9I78_15180	ENOG4105D1S	lipid A biosynthesis
C9I78_15185	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
C9I78_15190	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
C9I78_15200	ENOG4105DSJ	YicC domain protein
C9I78_15335	ENOG4108JQ7	(ABC) transporter
C9I78_15345	ENOG4107QRA	Extracellular solute-binding protein, family 5
C9I78_15355	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
C9I78_15365	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C9I78_15385	ENOG4109015	Biopolymer transport protein exbD tolR
C9I78_15400	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
C9I78_15405	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
C9I78_15410	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
C9I78_15415	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
C9I78_15420	ENOG4105CB5	ATP-dependent DNA helicase recG
C9I78_15430	ENOG4105C2W	permease
C9I78_15435	ENOG4105E0F	Histidine kinase
C9I78_15440	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C9I78_15450	ENOG4108RRZ	Transcription elongation factor GreB
C9I78_15460	ENOG4105BZM	domain protein
C9I78_15470	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
C9I78_15475	ENOG4105MJ2	Competence protein
C9I78_15480	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
C9I78_15485	ENOG4107RK2	ADP-ribose diphosphatase NudE
C9I78_15495	ENOG4105PIC	general secretion pathway protein N
C9I78_15500	ENOG4105U1E	general secretion pathway protein M
C9I78_15505	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
C9I78_15510	ENOG4108RTD	type II secretion system protein K
C9I78_15515	ENOG4108WWZ	General secretion pathway protein J
C9I78_15520	ENOG4105X5Z	General secretion pathway protein I
C9I78_15525	ENOG4105VWV	general secretion pathway protein h
C9I78_15530	ENOG4108VAU	general secretion pathway protein G
C9I78_15535	ENOG4105D7Q	type ii secretion system
C9I78_15540	ENOG4107QHF	type ii secretion system protein e
C9I78_15550	ENOG4108XKW	General secretion pathway protein C
C9I78_15555	ENOG4105VEJ	Heat shock protein
C9I78_15560	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
C9I78_15565	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
C9I78_15575	ENOG4105SUU	thioesterase domain
C9I78_15580	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
C9I78_15585	ENOG4107S2Z	UPF0761 membrane protein
C9I78_15605	ENOG4105C5F	glutamine synthetase
C9I78_15615	ENOG4105CUX	Signal transduction histidine kinase
C9I78_15620	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_15625	ENOG4105BZU	Histidine kinase
C9I78_15630	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C9I78_15635	ENOG4105D4P	Coproporphyrinogen iii oxidase
C9I78_15640	ENOG4105XCT	Protein of unknown function (DUF2489)
C9I78_15645	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
C9I78_15665	ENOG4106RE7	Cytochrome
C9I78_15670	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
C9I78_15680	ENOG4105C2M	dna polymerase I
C9I78_15695	ENOG4105D52	delta-aminolevulinic acid dehydratase
C9I78_15705	ENOG4105F8V	Hydrolase, tatD family
C9I78_15715	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
C9I78_15720	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
C9I78_15725	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
C9I78_15730	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C9I78_15735	ENOG4105JC1	sterol-binding domain protein
C9I78_15740	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
C9I78_15745	ENOG4105CGY	Dna recombination protein
C9I78_15755	ENOG4105BZU	Histidine kinase
C9I78_15760	ENOG4105DSF	transport protein
C9I78_15790	ENOG4107TE5	Lipid kinase
C9I78_15810	ENOG4105K3G	Periplasmic Protein
C9I78_15815	ENOG4108JUA	Transcriptional regulator
C9I78_15820	ENOG4105CBX	hi0933 family
C9I78_15825	ENOG4108V6B	universal stress protein B
C9I78_15830	ENOG41090A1	ferritin
C9I78_15835	ENOG4108M6U	Universal stress protein A
C9I78_15840	ENOG4105EMK	carboxylate amino acid amine transporter
C9I78_15850	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
C9I78_15855	ENOG4105BZU	Histidine kinase
C9I78_15860	ENOG4108VVK	transcriptional Regulator, AsnC
C9I78_15865	ENOG4105DGW	oligopeptidase A
C9I78_15875	ENOG4105D6S	protein involved in catabolism of external DNA
C9I78_15880	ENOG4105DC8	reductase
C9I78_15885	ENOG4107RSM	transcriptional regulator
C9I78_15890	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
C9I78_15895	ENOG4108UHU	Aldolase
C9I78_15900	ENOG4105C6Z	Gluconate
C9I78_15905	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
C9I78_15910	ENOG4105C01	Dihydroxy-acid dehydratase
C9I78_15915	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
C9I78_15920	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
C9I78_15925	ENOG41064T2	transcriptional regulator, lysR family
C9I78_15930	ENOG4105DIQ	Transcriptional regulator
C9I78_15935	ENOG4105D9P	serine threonine protein kinase
C9I78_15970	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
C9I78_15975	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
C9I78_15980	ENOG4105DEF	Extracellular solute-binding protein, family 5
C9I78_15985	ENOG4108JQ6	ABC transporter
C9I78_16035	ENOG4105MPD	Cytochrome
C9I78_16040	ENOG4105C4R	Atp-dependent dna helicase
C9I78_16045	ENOG41067SE	Tetr family transcriptional regulator
C9I78_16050	ENOG410624X	efflux transporter, rnd family, mfp subunit
C9I78_16055	ENOG4105BZS	acriflavin resistance protein
C9I78_16065	ENOG4105W0Z	cytoplasmic protein
C9I78_16070	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
C9I78_16075	ENOG4105EMY	transcriptional regulator
C9I78_16120	ENOG4108RR8	protoporphyrinogen oxidase
C9I78_16125	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
C9I78_16130	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
C9I78_16135	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
C9I78_16140	ENOG4105CHU	acetyl-coa acetyltransferase
C9I78_16145	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
C9I78_16160	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
C9I78_16175	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
C9I78_16180	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
C9I78_16185	ENOG4107T9C	Alpha amylase catalytic region
C9I78_16190	ENOG4105JKW	Valine--pyruvate aminotransferase
C9I78_16195	ENOG4108ZNX	Heat shock protein
C9I78_16215	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
C9I78_16220	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
C9I78_16225	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
C9I78_16230	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
C9I78_16240	ENOG4105EAB	amino acid AbC transporter
C9I78_16245	ENOG4105E5Q	amino acid AbC transporter
C9I78_16260	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
C9I78_16265	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
C9I78_16270	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
C9I78_16275	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
C9I78_16280	ENOG4105QTB	Flavodoxin
C9I78_16285	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
C9I78_16290	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
C9I78_16295	ENOG4107QJE	Chromosome Partitioning Protein
C9I78_16300	ENOG4105FA0	parb-like partition protein
C9I78_16305	ENOG410684E	atp synthase
C9I78_16310	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
C9I78_16315	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C9I78_16320	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C9I78_16325	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
C9I78_16330	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
C9I78_16335	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
C9I78_16340	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
C9I78_16345	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
C9I78_16350	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
C9I78_16355	ENOG4105EAD	ABC transporter
C9I78_16365	ENOG4105CZQ	inner membrane transport protein YdhC
C9I78_16370	ENOG4105F52	Transcriptional regulator
C9I78_16375	ENOG4105C7B	Threonine dehydratase
C9I78_16380	ENOG4105C01	Dihydroxy-acid dehydratase
C9I78_16385	ENOG4105CM2	brancheD-chain amino acid aminotransferase
C9I78_16390	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
C9I78_16400	ENOG4105C0P	Mg chelatase subunit ChlI
C9I78_16410	ENOG4106HNH	Acyl-transferase
C9I78_16415	ENOG4108Z33	Thiol disulfide Interchange Protein
C9I78_16420	ENOG4105E27	serine threonine protein kinase
C9I78_16430	ENOG4105PC1	Conserved Protein
C9I78_16440	ENOG4108N23	SpoOM-related protein
C9I78_16445	ENOG4108UT2	hemolysin iii
C9I78_16455	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
C9I78_16460	ENOG4105C1A	potassium transporter peripheral membrane
C9I78_16465	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
C9I78_16470	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
C9I78_16475	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C9I78_16485	ENOG4105C79	DNA protecting protein DprA
C9I78_16490	ENOG4108RPN	Protein smg homolog
C9I78_16495	ENOG4108WI1	Dna topoisomerase
C9I78_16500	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
C9I78_16505	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
C9I78_16510	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
C9I78_16515	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
C9I78_16520	ENOG4105E2X	shikimate dehydrogenase
C9I78_16525	ENOG4105SG3	Protein of unknown function (DUF1488)
C9I78_16530	ENOG4108Z0R	Transferase
C9I78_16595	ENOG4105WMR	Protein CrcB homolog
C9I78_16600	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
C9I78_16605	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C9I78_16610	ENOG4105D06	uba thif-type nad fad binding protein
C9I78_16615	ENOG4105WHD	thiamine biosynthesis protein ThiS
C9I78_16620	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
C9I78_16625	ENOG4105D41	biosynthesis protein thiH
C9I78_16630	ENOG4105DC7	peptidase M24
C9I78_16630	ENOG4105DC7	peptidase M24
C9I78_16660	ENOG4105E18	UPF0276 protein
C9I78_16670	ENOG4105C4R	Atp-dependent dna helicase
C9I78_16680	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
C9I78_16685	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
C9I78_16695	ENOG4105FR1	rard protein
C9I78_16700	ENOG4105C9U	ATP-dependent DNA helicase RecQ
C9I78_16715	ENOG4105EX9	Membrane
C9I78_16720	ENOG4105C9X	ppx gppa phosphatase
C9I78_16725	ENOG4105C1J	atp-dependent rna helicase
C9I78_16730	ENOG4105K63	Thioredoxin
C9I78_16735	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
C9I78_16750	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
C9I78_16755	ENOG4108ZIT	Ferredoxin, 2FE-2S
C9I78_16760	ENOG4107QK7	reductase
C9I78_16810	ENOG410601J	HemY protein
C9I78_16815	ENOG4105ECF	c-methyltransferase
C9I78_16820	ENOG41076E6	Uroporphyrinogen-III Synthase
C9I78_16825	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
C9I78_16830	ENOG4107T0K	Adenylate cyclase
C9I78_16835	ENOG4105XQ6	frataxin-like protein
C9I78_16845	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C9I78_16850	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
C9I78_16860	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C9I78_16865	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
C9I78_16870	ENOG4105BZU	Histidine kinase
C9I78_16875	ENOG4106IUH	DTW domain containing protein
C9I78_16890	ENOG4105DQF	Hydrolase
C9I78_16900	ENOG4108EUD	Lysophospholipase
C9I78_16905	ENOG410829K	Lysine exporter protein (Lyse ygga)
C9I78_16910	ENOG4105D58	Diguanylate phosphodiesterase
C9I78_16915	ENOG41082YX	Transcriptional regulator, arsr family
C9I78_16920	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
C9I78_16980	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
C9I78_16985	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
C9I78_17000	ENOG4105C7H	Helicase, RecD TraA family
C9I78_17035	ENOG4106H78	methyltransferase
C9I78_17040	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
C9I78_17045	ENOG4105CAK	Cell division ATP-binding protein ftsE
C9I78_17050	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
C9I78_17055	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
C9I78_17065	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
C9I78_17070	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
C9I78_17075	ENOG4105X6C	Flagellar basal body-associated protein FliL
C9I78_17080	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
C9I78_17085	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
C9I78_17090	ENOG4105E55	glycerol-3-phosphate acyltransferase
C9I78_17105	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
C9I78_17115	ENOG4107R73	Mate efflux family protein
C9I78_17120	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
C9I78_17135	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
C9I78_17140	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C9I78_17150	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
C9I78_17220	ENOG4105JIM	Phosphatidylserine synthase
C9I78_17230	ENOG4105D4A	Cell wall formation (By similarity)
C9I78_17235	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
C9I78_17240	ENOG4105CS9	pantothenic acid kinase
C9I78_17260	ENOG4108C33	Resolvase
C9I78_17285	ENOG4105C7H	Helicase, RecD TraA family
C9I78_17315	ENOG4108C33	Resolvase
C9I78_17360	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
C9I78_17365	ENOG4108K0B	C-di-gmp phosphodiesterase
C9I78_17370	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
C9I78_17375	ENOG4105C2J	ABC transporter
C9I78_17380	ENOG4105CNN	ABC, transporter
C9I78_17385	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
C9I78_17390	ENOG4108RVA	ribokinase
C9I78_17395	ENOG4105ETE	Transcriptional regulator (LacI family
C9I78_17405	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
C9I78_17410	ENOG4108I5U	Uridine phosphorylase
C9I78_17430	ENOG4105ETX	regulatoR
C9I78_17445	ENOG4105G6Z	alkaline phosphatase
C9I78_17465	ENOG4105BZU	Histidine kinase
C9I78_17475	ENOG4105C44	Serine transporter
C9I78_17480	ENOG4108R6G	acetyltransferase
C9I78_17490	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C9I78_17520	ENOG4105D7T	ABC transporter
C9I78_17525	ENOG4105DG7	nitrate ABC transporter
C9I78_17530	ENOG4105D7T	ABC transporter
C9I78_17535	ENOG4107QZF	nitrite reductase NADPH large subunit
C9I78_17550	ENOG4108IG5	Transcriptional regulator
C9I78_17565	ENOG4105F8J	Adenylate Guanylate cyclase
C9I78_17590	ENOG4105D9P	serine threonine protein kinase
C9I78_17615	ENOG4106VK6	Flagellar motor protein
C9I78_17630	ENOG4108ZF3	Phosphatase
C9I78_17675	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
C9I78_17700	ENOG4107RFY	SbcCD D subunit
C9I78_17705	ENOG4105EYH	Exonuclease
C9I78_17725	ENOG4105QNF	Outer membrane lipoprotein
C9I78_17735	ENOG4105C2C	drug resistance transporter, Bcr CflA
C9I78_17745	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
C9I78_17755	ENOG4106RE7	Cytochrome
C9I78_17760	ENOG4105C5W	Aldolase
C9I78_17770	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
C9I78_17775	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
C9I78_17795	ENOG4105CC0	LysR family Transcriptional regulator
C9I78_17800	ENOG4105CXG	d-lactate dehydrogenase
C9I78_17820	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
C9I78_17825	ENOG4108NVR	Methyl-accepting chemotaxis
C9I78_17860	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
C9I78_17910	ENOG4105NXH	GreA GreB family elongation factor
C9I78_17915	ENOG4107QZF	nitrite reductase NADPH large subunit
C9I78_17920	ENOG4105WZK	nitrite reductase NADPH small subunit
C9I78_17925	ENOG4105TMB	Formate nitrite transporter
C9I78_17930	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
C9I78_17945	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
C9I78_17975	ENOG4105VXR	cytoplasmic protein
C9I78_17980	ENOG4107QI1	Mate efflux family protein
C9I78_17990	ENOG4108ISG	Major Facilitator
C9I78_17995	ENOG4105K63	Thioredoxin
C9I78_18000	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
C9I78_18020	ENOG4105EIP	mannose-6-phosphate isomerase
C9I78_18025	ENOG4105CXY	transporter
C9I78_18030	ENOG4105BZU	Histidine kinase
C9I78_18035	ENOG4108KX4	response regulator
C9I78_18040	ENOG4105CXY	transporter
C9I78_18045	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
C9I78_18050	ENOG4105C5Q	Transcriptional regulator
C9I78_18060	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
C9I78_18065	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
C9I78_18110	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
C9I78_18160	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
C9I78_18165	ENOG4105KT5	UmuD protein
C9I78_18205	ENOG4108QDQ	Ubiquinol-cytochrome C chaperone 
C9I78_18295	ENOG4105CAF	HipA N-terminal domain protein
C9I78_18330	ENOG4105BZS	acriflavin resistance protein
C9I78_18350	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
C9I78_18355	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
C9I78_18360	ENOG4107QI1	Mate efflux family protein
C9I78_18370	ENOG4105ECQ	AraC Family Transcriptional Regulator
C9I78_18375	ENOG4105CGF	Aromatic amino acid aminotransferase
C9I78_18380	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
C9I78_18390	ENOG4105WXI	Bacterial OB fold (BOF) protein
C9I78_18395	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
C9I78_18400	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
C9I78_18405	ENOG4105E0C	molybdate abc transporter
C9I78_18410	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
C9I78_18430	ENOG4105BZU	Histidine kinase
C9I78_18445	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C9I78_18450	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
C9I78_18480	ENOG4108M6U	Universal stress protein A
C9I78_18490	ENOG4105EJC	lysr family transcriptional regulator
C9I78_18505	ENOG4108ZJT	translation initiation factor, Sui1
C9I78_18515	ENOG4105CPF	Cell wall formation (By similarity)
C9I78_18525	ENOG4105CD5	CoA-binding domain protein
C9I78_18530	ENOG4105CWB	LysR family transcriptional Regulator
C9I78_18545	ENOG4105CMR	udp-glucose 4-epimerase
C9I78_18550	ENOG4105BZU	Histidine kinase
C9I78_18555	ENOG4105E7W	lamb ycsf family protein
C9I78_18560	ENOG4105P4J	Allophanate hydrolase, subunit 1
C9I78_18565	ENOG4107R7A	Allophanate hydrolase subunit 2
C9I78_18575	ENOG4105CV6	ABC transporter, permease
C9I78_18580	ENOG4108I0Y	(ABC) transporter
C9I78_18590	ENOG4105RKW	reductase (By
C9I78_18595	ENOG4105BZU	Histidine kinase
C9I78_18605	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
C9I78_18630	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
C9I78_18640	ENOG4105KA0	thioesterase Superfamily protein
C9I78_18655	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
C9I78_18660	ENOG4108M0H	Extracellular lipase
C9I78_18675	ENOG4105DU1	integral membrane protein, terc
C9I78_18680	ENOG4105CGH	5'-nucleotidase
C9I78_18685	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
C9I78_18690	ENOG4108UQ5	membrane protein YcdZ
C9I78_18695	ENOG4105DUM	transcriptional regulator, lysR family
C9I78_18700	ENOG4105TMB	Formate nitrite transporter
C9I78_18705	ENOG4108YYC	ycei family
C9I78_18710	ENOG4105DS1	cytochrome b561
C9I78_18725	ENOG4108M8H	domain protein
C9I78_18730	ENOG4105C1J	atp-dependent rna helicase
C9I78_18735	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
C9I78_18755	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
C9I78_18765	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
C9I78_18785	ENOG4107RE1	Inosine-guanosine kinase
C9I78_18790	ENOG4105CKU	formyltetrahydrofolate synthetase
C9I78_18795	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
C9I78_18810	ENOG4105CF7	AraC family transcriptional regulator
C9I78_18815	ENOG4108I6A	alcohol dehydrogenase
C9I78_18825	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
C9I78_18835	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
C9I78_18840	ENOG4105CXY	transporter
C9I78_18845	ENOG4105CA9	Pyruvate kinase
C9I78_18850	ENOG4105CDA	abc transporter atp-binding protein
C9I78_18855	ENOG4105E5Q	amino acid AbC transporter
C9I78_18860	ENOG4106TNF	Periplasmic binding protein
C9I78_18865	ENOG4105DRP	amino acid AbC transporter
C9I78_18870	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
C9I78_18890	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
C9I78_18895	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
C9I78_18900	ENOG4105DE4	1-phosphofructokinase
C9I78_18905	ENOG4105DM4	PTS System
C9I78_18945	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
C9I78_18950	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
C9I78_18955	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C9I78_18995	ENOG4105C5W	Aldolase
C9I78_19005	ENOG4105CR8	Transcriptional regulator
C9I78_19010	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
C9I78_19035	ENOG4105HDD	phospholipase
C9I78_19055	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
C9I78_19085	ENOG4105CJW	magnesium transporter
C9I78_19105	ENOG4108UYE	Lactoylglutathione lyase
C9I78_19110	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C9I78_19135	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
C9I78_19145	ENOG4105CBC	glutamate synthase
C9I78_19155	ENOG4106YYS	transcriptional regulatory protein
C9I78_19160	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
C9I78_19165	ENOG4107QPK	)-transporter
C9I78_19170	ENOG4107RGH	Aldehyde dehydrogenase
C9I78_19190	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
C9I78_19210	ENOG4106CKV	Pap2 superfamily protein
C9I78_19225	ENOG4105FR1	rard protein
C9I78_19245	ENOG4107R88	Chemotaxis protein (CheV)
C9I78_19270	ENOG4108WQH	regulatoR
C9I78_19280	ENOG4105BZU	Histidine kinase
C9I78_19285	ENOG4108WQH	regulatoR
C9I78_19290	ENOG4105BZU	Histidine kinase
C9I78_19295	ENOG4105BZU	Histidine kinase
C9I78_19315	ENOG4105CDV	Ompa motb domain protein
C9I78_19390	ENOG4106R3P	AraC family transcriptional regulator
C9I78_19400	ENOG4105KXC	Collagenase
C9I78_19410	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
C9I78_19415	ENOG4107KBT	8-Amino-7-oxononanoate synthase
C9I78_19420	ENOG4108MGY	Histidine kinase
C9I78_19440	ENOG4105CEE	C4-dicarboxylate transporter
C9I78_19445	ENOG4108V0P	LemA family
C9I78_19450	ENOG4105D0M	Protease HtpX homolog
C9I78_19470	ENOG4105F2V	VRR-NUC domain-containing protein
C9I78_19480	ENOG4105C4X	radical SAM domain protein
C9I78_19500	ENOG4108YDI	single-species biofilm formation on inanimate substrate
C9I78_19505	ENOG4107TE5	Lipid kinase
C9I78_19510	ENOG41064T2	transcriptional regulator, lysR family
C9I78_19515	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
C9I78_19545	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C9I78_19550	ENOG4105C4X	radical SAM domain protein
C9I78_19555	ENOG4105ENH	Sulfatase
C9I78_19570	ENOG4105ENH	Sulfatase
C9I78_19575	ENOG4105ENH	Sulfatase
C9I78_19580	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C9I78_19595	ENOG4105BZU	Histidine kinase
C9I78_19600	ENOG4108SV3	Tmao reductase system periplasmic protein tort
C9I78_19605	ENOG4108Z5K	methylglyoxal synthase
C9I78_19610	ENOG41088T4	Helicase IV
C9I78_19615	ENOG4105EM2	membrane
C9I78_19650	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
C9I78_19665	ENOG4108Z6Z	Transcriptional regulator
C9I78_19670	ENOG4108IPW	abc transporter atp-binding protein
C9I78_19675	ENOG4105CM4	permease protein
C9I78_19680	ENOG4105DHS	permease protein
C9I78_19710	ENOG4106E5D	Protein of unknown function (DUF461)
C9I78_19715	ENOG4105R8A	Heat shock protein
C9I78_19730	ENOG4107RUY	(E1 component), alpha subunit
C9I78_19735	ENOG4105CPP	Dehydrogenase, E1 component
C9I78_19740	ENOG4107QSN	dihydrolipoamide acetyltransferase
C9I78_19745	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
C9I78_19750	ENOG4107MKT	Stringent starvation protein a
C9I78_19755	ENOG4105DUM	transcriptional regulator, lysR family
C9I78_19765	ENOG4105DMR	ABC, transporter
C9I78_19770	ENOG4105GBT	ABC transporter
C9I78_19775	ENOG4106PMH	Extracellular solute-binding protein family 3
C9I78_19780	ENOG4105E5Z	arginine transporter ATP-binding subunit
C9I78_19810	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C9I78_19815	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C9I78_19825	ENOG4105CCU	oxidase (Subunit III)
C9I78_19830	ENOG4105BZ9	Cytochrome C oxidase, subunit I
C9I78_19835	ENOG4105E2S	oxidase) subunit II
C9I78_19845	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C9I78_19850	ENOG4105E39	Enoyl-CoA hydratase
C9I78_19865	ENOG4105C26	Dehydrogenase
C9I78_19870	ENOG4105CHU	acetyl-coa acetyltransferase
C9I78_19880	ENOG4105C1G	acyl-Coa dehydrogenase
C9I78_19885	ENOG4107QX3	carboxylase
C9I78_19890	ENOG4105CGU	Enoyl-CoA hydratase
C9I78_19895	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C9I78_19910	ENOG4107SDU	Methyl-accepting chemotaxis
C9I78_19915	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
C9I78_19925	ENOG4105BZU	Histidine kinase
C9I78_19930	ENOG4105C1J	atp-dependent rna helicase
C9I78_19935	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
C9I78_19950	ENOG4107S17	Phosphate-binding protein
C9I78_19970	ENOG4108N3W	hemolysin secretion protein
C9I78_19975	ENOG4105DKW	ABC transporter
C9I78_19980	ENOG4105CXC	rtn protein
C9I78_20000	ENOG4105C1J	atp-dependent rna helicase
C9I78_20005	ENOG4105CKI	cobalamin synthesis protein
C9I78_20015	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
C9I78_20025	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
C9I78_20030	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
C9I78_20035	ENOG4105C1J	atp-dependent rna helicase
C9I78_20040	ENOG4105VRT	cytoplasmic protein
C9I78_20065	ENOG41090A4	Pterin carbinolamine dehydratase
C9I78_20070	ENOG4105MIR	Phenylalanine 4-monooxygenase
C9I78_20075	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C9I78_20080	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
C9I78_20115	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
C9I78_20120	ENOG4105C0A	alcohol dehydrogenase
C9I78_20135	ENOG4108RMU	ferritin dps family protein
C9I78_20140	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_20150	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C9I78_20170	ENOG4105BZU	Histidine kinase
C9I78_20180	ENOG4107SDU	Methyl-accepting chemotaxis
C9I78_20190	ENOG4105VEQ	Cold shock protein
C9I78_20225	ENOG4108V1T	peptidylprolyl cis-trans isomerase
C9I78_20230	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
C9I78_20235	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
C9I78_20255	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
C9I78_20260	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
C9I78_20290	ENOG4105SUT	Transcriptional Regulator AraC Family
C9I78_20320	ENOG4108SXK	Transporter Drug Metabolite Exporter family
C9I78_20325	ENOG4105VW4	glutaredoxin 3
C9I78_20345	ENOG4105E5M	Multidrug resistance protein D
C9I78_20350	ENOG4105CR8	Transcriptional regulator
C9I78_20360	ENOG4105DR5	peptidase
C9I78_20385	ENOG4105DWD	nucleoside recognition domain protein
C9I78_20390	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_20400	ENOG4105E0U	tyrosine-specific transport protein
C9I78_20425	ENOG4107Z1W	Fructose transport system kinase
C9I78_20435	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
C9I78_20440	ENOG4105CTS	PTS system mannitol-specific
C9I78_20445	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
C9I78_20465	ENOG4105D6J	arsenicaL-resistance protein
C9I78_20475	ENOG4108V1U	phospholipid-binding protein
C9I78_20480	ENOG4105JAB	phenazine biosynthesis protein, phzf family
C9I78_20485	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
C9I78_20500	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_20510	ENOG4105CJ1	ABC, transporter
C9I78_20515	ENOG4107QWP	ABC-2 type transporter
C9I78_20530	ENOG4108IEG	Formate dehydrogenase Alpha subunit
C9I78_20555	ENOG4108IJF	Heavy metal efflux pump, CzcA
C9I78_20575	ENOG410620I	Diguanylate cyclase
C9I78_20585	ENOG4108HK0	-acetyltransferase
C9I78_20595	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
C9I78_20605	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
C9I78_20620	ENOG4105C5H	ABC transporter
C9I78_20625	ENOG4108M6U	Universal stress protein A
C9I78_20630	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
C9I78_20635	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
C9I78_20660	ENOG4105KXC	Collagenase
C9I78_20675	ENOG4105C5Q	Transcriptional regulator
C9I78_20690	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
C9I78_20725	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
C9I78_20735	ENOG4107R88	Chemotaxis protein (CheV)
C9I78_20745	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
C9I78_20750	ENOG41090JE	Utilization Protein
C9I78_20755	ENOG4105D4P	Coproporphyrinogen iii oxidase
C9I78_20760	ENOG4105WQ5	TonB family
C9I78_20765	ENOG41090AP	transport protein
C9I78_20770	ENOG4106GFD	transport protein
C9I78_20780	ENOG4105EHG	Permease protein
C9I78_20785	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
C9I78_20830	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
C9I78_20835	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
C9I78_20840	ENOG4105QVC	MOSC domain-containing protein
C9I78_20840	ENOG4105QVC	MOSC domain-containing protein
C9I78_20860	ENOG4105EKE	dihydroorotase
C9I78_20865	ENOG4105CKW	Inner membrane protein yedI
C9I78_20895	ENOG410874W	AraC family transcriptional regulator
C9I78_20900	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C9I78_20945	ENOG4105C1J	atp-dependent rna helicase
C9I78_20955	ENOG4107RSM	transcriptional regulator
C9I78_20970	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
C9I78_20975	ENOG4105CPQ	Dehydrogenase
C9I78_20985	ENOG4105CHR	reductase
C9I78_20990	ENOG4108ZX5	transcriptional regulator
C9I78_21000	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
C9I78_21025	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
C9I78_21030	ENOG4105HDK	L-asparaginase
C9I78_21035	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
C9I78_21040	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
C9I78_21060	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
C9I78_21065	ENOG4107RUE	extracellular solute-binding protein family 1
C9I78_21080	ENOG4107KET	secretion protein, HlyD family
C9I78_21100	ENOG4105BZU	Histidine kinase
C9I78_21110	ENOG41086KC	Transcriptional regulator
C9I78_21150	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
C9I78_21195	ENOG4107RZC	phospholipase d
C9I78_21225	ENOG4108Z4X	TRANSCRIPTIONal
C9I78_21245	ENOG4105RQF	LysR family Transcriptional regulator
C9I78_21255	ENOG4107S8C	mandelate racemase muconate lactonizing
C9I78_21265	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
C9I78_21290	ENOG4105VYW	UPF0251 protein
C9I78_21300	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
C9I78_21310	ENOG4105RW8	MltA-interacting MipA family protein
C9I78_21325	ENOG4105ETT	transcriptional Regulator, LysR family
C9I78_21350	ENOG4107RH7	Nicotinate phosphoribosyltransferase
C9I78_21360	ENOG4108RWI	nicotinamidase
C9I78_21370	ENOG4105CH6	catalase
C9I78_21380	ENOG4105N2W	Transcriptional regulator
C9I78_21385	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
C9I78_21390	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
C9I78_21405	ENOG4105DM4	PTS System
C9I78_21410	ENOG4105CWX	Alpha-1,2-mannosidase
C9I78_21415	ENOG4105CWX	Alpha-1,2-mannosidase
C9I78_21425	ENOG4105CWX	Alpha-1,2-mannosidase
C9I78_21430	ENOG4105CWX	Alpha-1,2-mannosidase
C9I78_21435	ENOG4105EA8	2-Nitropropane dioxygenase
C9I78_21440	ENOG4105CGH	5'-nucleotidase
C9I78_21450	ENOG4107Z3H	Transcriptional regulator, TetR family
C9I78_21470	ENOG4105N14	lysine exporter protein LysE YggA
C9I78_21485	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
C9I78_21490	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
C9I78_21495	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
C9I78_21520	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
C9I78_21540	ENOG4105DTJ	flagellar hook-associated protein
C9I78_21550	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
C9I78_21555	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C9I78_21560	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
C9I78_21565	ENOG4105CGA	flagellar basal-body rod protein FlgG
C9I78_21570	ENOG4108KPB	Flagellar basal-body rod protein FlgF
C9I78_21575	ENOG4105BZE	flagellar hook protein, FlgE
C9I78_21580	ENOG4105W00	Flagellar hook capping protein
C9I78_21585	ENOG4108ZC9	flagellar basal-body rod protein flgc
C9I78_21590	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
C9I78_21610	ENOG4105E4C	Lytic transglycosylase catalytic
C9I78_21615	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
C9I78_21635	ENOG4105EJQ	L-serine dehydratase
C9I78_21640	ENOG4105DUX	Transporter
C9I78_21660	ENOG4105ETT	transcriptional Regulator, LysR family
C9I78_21680	ENOG4105CJP	fad dependent oxidoreductase
C9I78_21690	ENOG4108MJ5	VirK protein
C9I78_21710	ENOG4107RCV	ABC transporter, permease
C9I78_21735	ENOG4108JPW	Aminotransferase
C9I78_21740	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
C9I78_21745	ENOG4105ETE	Transcriptional regulator (LacI family
C9I78_21770	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
C9I78_21775	ENOG4105KUU	lipolytic protein G-D-S-L family
C9I78_21785	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
C9I78_21790	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
C9I78_21795	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
C9I78_21805	ENOG4108UUE	Transcriptional regulator
C9I78_21820	ENOG4105PAD	Hydrolase
C9I78_21825	ENOG4105JQN	Transcriptional regulator
C9I78_21860	ENOG4108UW5	maltose o-acetyltransferase
C9I78_21865	ENOG4108UKZ	OsmC family
C9I78_21870	ENOG4105E0X	reductase
C9I78_21885	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
C9I78_21890	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C9I78_21895	ENOG4106TD9	Diguanylate cyclase
C9I78_21910	ENOG4108N3W	hemolysin secretion protein
C9I78_21915	ENOG4105BZU	Histidine kinase
C9I78_21920	ENOG4105CF1	Alkylated DNA repair protein
C9I78_21930	ENOG4105D9N	nucleoside
C9I78_21950	ENOG4105C0F	tryptophanase EC 4.1.99.1
C9I78_21960	ENOG4105D5U	fad dependent oxidoreductase
C9I78_21985	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
C9I78_21990	ENOG4105BZU	Histidine kinase
C9I78_21995	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_22035	ENOG4108WAV	Transcriptional regulator
C9I78_22045	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
C9I78_22050	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
C9I78_22060	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
C9I78_22065	ENOG4105CYW	agmatinase
C9I78_22070	ENOG4105E5M	Multidrug resistance protein D
C9I78_22075	ENOG4105CUG	Oligopeptidase b
C9I78_22090	ENOG4105CC5	ABC transporter
C9I78_22095	ENOG4105DIK	(ABC) transporter
C9I78_22100	ENOG4105DSE	periplasmic solute binding protein
C9I78_22140	ENOG4109015	Biopolymer transport protein exbD tolR
C9I78_22165	ENOG410804D	Sensor Signal Transduction Histidine Kinase
C9I78_22170	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
C9I78_22175	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
C9I78_22180	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
C9I78_22190	ENOG4105C5I	Dehydrogenase
C9I78_22195	ENOG4108YYI	Protein of unknown function (DUF2810)
C9I78_22250	ENOG4108TEM	pseudouridine methyltransferase
C9I78_22270	ENOG4105DWF	phosphomethylpyrimidine kinase
C9I78_22275	ENOG4108YI8	ABC transporter
C9I78_22280	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
C9I78_22285	ENOG4107Z6I	Thiamine biosynthesis protein
C9I78_22290	ENOG4105ETU	transcriptional activator (TenA
C9I78_22295	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
C9I78_22300	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
C9I78_22310	ENOG4107QY8	reductase
C9I78_22315	ENOG4105CUW	cytochrome C-TYPE protein
C9I78_22325	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
C9I78_22360	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C9I78_22365	ENOG4105BZW	Glycerate kinase
C9I78_22370	ENOG4105C6Z	Gluconate
C9I78_22375	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
C9I78_22400	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
C9I78_22425	ENOG4108WAV	Transcriptional regulator
C9I78_22430	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
C9I78_22435	ENOG4108UVJ	appr-1-p processing domain protein
C9I78_22440	ENOG4107WCA	isomerase
C9I78_22460	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
C9I78_22470	ENOG4105EIF	outer membrane protein W
C9I78_22475	ENOG4107W31	Pentapeptide repeat protein
C9I78_22490	ENOG4108M1A	Chitin-binding protein
C9I78_22495	ENOG4105EW9	transcriptional regulator AsnC family
C9I78_22505	ENOG4105Q26	Siderophore-interacting protein
C9I78_22510	ENOG4105CAZ	oligogalacturonide lyase
C9I78_22535	ENOG4108UHU	Aldolase
C9I78_22540	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
C9I78_22555	ENOG4105M5J	Cupin 2, conserved barrel domain protein
C9I78_22560	ENOG4105P66	Membrane
C9I78_22565	ENOG4105CHR	reductase
C9I78_22570	ENOG4105J4Q	Transcriptional regulator
C9I78_22585	ENOG4105CC0	LysR family Transcriptional regulator
C9I78_22590	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
C9I78_22600	ENOG4105C4W	S-formylglutathione hydrolase
C9I78_22610	ENOG4108KHX	Diguanylate cyclase
C9I78_22620	ENOG4108HCJ	Hydrolase
C9I78_22625	ENOG4105EJC	lysr family transcriptional regulator
C9I78_22640	ENOG4105D3G	Pseudouridine synthase
C9I78_22645	ENOG4105UQX	Mate efflux family protein
C9I78_22655	ENOG4108K0B	C-di-gmp phosphodiesterase
C9I78_22665	ENOG4105NBK	UPF0345 protein
C9I78_22695	ENOG4105DN9	Na H antiporter
C9I78_22715	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
C9I78_22720	ENOG4105D03	DNA-3-methyladenine glycosylase II
C9I78_22735	ENOG4108VGI	doxx family
C9I78_22740	ENOG4105C2I	pirin domain protein
C9I78_22760	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
C9I78_22775	ENOG4105D6U	Sodium Glutamate Symporter
C9I78_22780	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C9I78_22785	ENOG4105DVE	abc transporter atp-binding protein
C9I78_22795	ENOG4105D6U	Sodium Glutamate Symporter
C9I78_22825	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_22830	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
C9I78_22840	ENOG4108VAC	response regulator
C9I78_22845	ENOG4108HRK	Histidine kinase
C9I78_22865	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
C9I78_22880	ENOG4105CNI	cell division protein FtsW
C9I78_22885	ENOG4105CDY	transcriptional regulatory protein
C9I78_22895	ENOG4105BZU	Histidine kinase
C9I78_22925	ENOG4108JQ7	(ABC) transporter
C9I78_22950	ENOG4106RMF	ParB family
C9I78_22955	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
C9I78_22970	ENOG4105EQ2	LysR family Transcriptional regulator
C9I78_22975	ENOG4105EC3	peptidase S51, dipeptidase E
C9I78_22980	ENOG4105FCK	Membrane
C9I78_22985	ENOG4105C5Y	PTS System
C9I78_22990	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C9I78_23000	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
C9I78_23010	ENOG4108J59	Extracellular solute-binding protein, family 5
C9I78_23025	ENOG4108JJA	ABC, transporter
C9I78_23040	ENOG4107QZV	Type I secretion membrane fusion protein
C9I78_23045	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_23050	ENOG4105CQZ	Histidine kinase
C9I78_23060	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
C9I78_23080	ENOG4105C26	Dehydrogenase
C9I78_23090	ENOG4105CK7	Sodium proline symporter
C9I78_23125	ENOG4105EW9	transcriptional regulator AsnC family
C9I78_23135	ENOG4105BZ1	(ABC) transporter
C9I78_23145	ENOG4105CF7	AraC family transcriptional regulator
C9I78_23165	ENOG4105P66	Membrane
C9I78_23170	ENOG4108UHU	Aldolase
C9I78_23185	ENOG4105DEI	Mannitol dehydrogenase
C9I78_23190	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
C9I78_23195	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
C9I78_23200	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
C9I78_23205	ENOG4105C6F	GntR Family Transcriptional Regulator
C9I78_23210	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
C9I78_23215	ENOG4105C1J	atp-dependent rna helicase
C9I78_23220	ENOG4108RPX	mosc domain containing protein
C9I78_23235	ENOG4105F8D	glycoside hydrolase family 4
C9I78_23240	ENOG4105W8I	Transcriptional regulator
C9I78_23245	ENOG4108N3W	hemolysin secretion protein
C9I78_23260	ENOG4105DU6	RNA polymerase
C9I78_23265	ENOG4105ECQ	AraC Family Transcriptional Regulator
C9I78_23275	ENOG4105EXG	Transcriptional regulator
C9I78_23295	ENOG4108JU3	Alkyl hydroperoxide reductase
C9I78_23300	ENOG4105D3R	alkyl hydroperoxide reductase
C9I78_23305	ENOG4105K56	Transcriptional regulator
C9I78_23310	ENOG4108ZHJ	Organic hydroperoxide resistance protein
C9I78_23335	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
C9I78_23345	ENOG4105EF1	ribulokinase
C9I78_23350	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
C9I78_23355	ENOG4105C2J	ABC transporter
C9I78_23360	ENOG4105CNN	ABC, transporter
C9I78_23375	ENOG4105CI1	PTS System
C9I78_23385	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C9I78_23390	ENOG4105DHQ	Histidine kinase
C9I78_23395	ENOG4108JP0	extracellular solute-binding protein family 1
C9I78_23400	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
C9I78_23405	ENOG4105DBM	Siderophore biosynthesis protein
C9I78_23415	ENOG4105DUU	IucA IucC family protein
C9I78_23425	ENOG4105E0K	tonB-dependent siderophore receptor
C9I78_23430	ENOG4105GAV	receptor
C9I78_23435	ENOG4108HUF	Transporter
C9I78_23440	ENOG4105DQ5	transport system permease protein
C9I78_23445	ENOG4108U1V	ABC transporter, permease
C9I78_23450	ENOG4105E0A	ABC, transporter
C9I78_23455	ENOG4105C8Q	Methyl-accepting chemotaxis
C9I78_23460	ENOG4107RAN	Peptidase, M16
C9I78_23470	ENOG4105DR5	peptidase
C9I78_23480	ENOG4105E5M	Multidrug resistance protein D
C9I78_23495	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
C9I78_23520	ENOG4108K8S	endonuclease I
C9I78_23540	ENOG4105CXN	decarboxylase
C9I78_23545	ENOG4105D5Q	Arginine ornithine antiporter
C9I78_23555	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
C9I78_23565	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
C9I78_23570	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
C9I78_23600	ENOG41061ZR	Transcriptional regulator
C9I78_23615	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
C9I78_23620	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
C9I78_23625	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
C9I78_23630	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
C9I78_23635	ENOG4107T9C	Alpha amylase catalytic region
C9I78_23650	ENOG41074DU	domain protein
C9I78_23655	ENOG4108P2H	Inner membrane protein YjiG
C9I78_23660	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
C9I78_23670	ENOG4105CK2	sodium dicarboxylate symporter
C9I78_23700	ENOG4105F04	LysR family Transcriptional regulator
C9I78_23705	ENOG4105N0V	mono-oxygenase ydhR
C9I78_23715	ENOG4105D75	Capsular exopolysaccharide family
C9I78_23725	ENOG4105DAY	polysaccharide export protein
C9I78_23735	ENOG41081FY	multiple antibiotic resistance (MarC)-related
C9I78_23740	ENOG4108NRW	Phospholipase, patatin family
C9I78_23745	ENOG4108M1A	Chitin-binding protein
C9I78_23750	ENOG4105C72	UPF0176 protein
C9I78_23765	ENOG4105DZ1	carboxypeptidase
C9I78_23780	ENOG4108RCM	Nitroreductase
C9I78_23790	ENOG4105ETT	transcriptional Regulator, LysR family
C9I78_23795	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
C9I78_23805	ENOG4105DP0	ferredoxin-NADP reductase
C9I78_23815	ENOG41068P6	UPF0319 protein
C9I78_23820	ENOG4105IPI	Membrane
C9I78_23860	ENOG4105G2Y	Transcriptional regulator
C9I78_23865	ENOG4105CNH	Multidrug resistance protein MdtL
C9I78_23875	ENOG4105I4A	GCN5-related N-acetyltransferase
C9I78_23885	ENOG4107T9Z	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C9I78_23890	ENOG4105F1A	Pyruvate formate-lyase
C9I78_23895	ENOG4105C6N	Formate acetyltransferase
C9I78_23935	ENOG4105KWG	Pfam:DUF1696
C9I78_23945	ENOG4105ER2	Ompa motb domain protein
C9I78_23950	ENOG4107RD7	Flagellar Motor Protein, MotA
C9I78_23975	ENOG4105MQ3	flagellar protein FliS
C9I78_23980	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
C9I78_23990	ENOG4105I03	Flagellin
C9I78_24005	ENOG4105D00	flagellar biosynthetic protein flhB
C9I78_24010	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
C9I78_24015	ENOG4105VS8	Flagellar biosynthetic protein fliq
C9I78_24020	ENOG4105CN7	Flagellar biosynthetic protein FliP
C9I78_24025	ENOG4105DD5	Flagellar motor switch protein
C9I78_24040	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
C9I78_24050	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
C9I78_24055	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
C9I78_24065	ENOG4108JIR	Flagellum-specific ATP synthase
C9I78_24095	ENOG4107SSZ	Phosphatase
C9I78_24115	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
C9I78_24120	ENOG4105EXG	Transcriptional regulator
C9I78_24150	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
C9I78_24160	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
C9I78_24170	ENOG4107R0W	ABC transporter
C9I78_24175	ENOG4105BZU	Histidine kinase
C9I78_24180	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
C9I78_24185	ENOG4105CPQ	Dehydrogenase
C9I78_24225	ENOG4105D64	Mechanosensitive ion channel
C9I78_24235	ENOG4105DMF	Dehydrogenase
C9I78_24240	ENOG4105DAA	L-lactate
C9I78_24245	ENOG4105CR8	Transcriptional regulator
C9I78_24255	ENOG4108JQ5	ABC transporter
C9I78_24265	ENOG4105DAN	ATP-dependent protease
C9I78_24270	ENOG4108NVR	Methyl-accepting chemotaxis
C9I78_24275	ENOG4105YE1	PilZ domain
C9I78_24295	ENOG4105WCN	acetyltransferase
C9I78_24300	ENOG4108BGM	Quinol dehydrogenase periplasmic component
C9I78_24305	ENOG4105GXZ	Ferredoxin-type protein NapH
C9I78_24320	ENOG4108JJB	ABC transporter
C9I78_24325	ENOG4108V7D	UPF0397 protein
C9I78_24330	ENOG4105EFX	secretion protein, HlyD family
C9I78_24335	ENOG4105KK7	inner membrane protein YiaW
C9I78_24340	ENOG4106TD9	Diguanylate cyclase
C9I78_24355	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
C9I78_24365	ENOG4107SEY	Conserved Protein
C9I78_24370	ENOG4108XDN	Transcriptional regulator
C9I78_24375	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
C9I78_24380	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
C9I78_24390	ENOG4105C1J	atp-dependent rna helicase
C9I78_24395	ENOG4105CUG	Oligopeptidase b
C9I78_24400	ENOG4105D05	Receptor
C9I78_24420	ENOG4108NVR	Methyl-accepting chemotaxis
C9I78_24425	ENOG4107S17	Phosphate-binding protein
C9I78_24430	ENOG4105C8U	phosphate abc transporter
C9I78_24435	ENOG4105E2Z	phosphate ABC transporter (Permease
C9I78_24440	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
C9I78_24455	ENOG4107QVM	von Willebrand factor, type A
C9I78_24475	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
C9I78_24485	ENOG41069D7	Methyl-accepting chemotaxis
C9I78_24495	ENOG41086KC	Transcriptional regulator
C9I78_24500	ENOG41086KC	Transcriptional regulator
C9I78_24510	ENOG4108JJ6	Type I secretion system ATPase
C9I78_24530	ENOG4105KCK	Peptidoglycan-associated lipoprotein
C9I78_24540	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
C9I78_24545	ENOG4108HUF	Transporter
C9I78_24550	ENOG4105E0A	ABC, transporter
C9I78_24555	ENOG4105E0K	tonB-dependent siderophore receptor
C9I78_24560	ENOG4105BZ1	(ABC) transporter
C9I78_24565	ENOG4105BZU	Histidine kinase
C9I78_24580	ENOG4105CZN	Potassium uptake protein
C9I78_24585	ENOG4105BZU	Histidine kinase
C9I78_24595	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
C9I78_24605	ENOG4105EIP	mannose-6-phosphate isomerase
C9I78_24610	ENOG4105DM4	PTS System
C9I78_24615	ENOG4106R3P	AraC family transcriptional regulator
C9I78_24625	ENOG4108YRF	PTS System
C9I78_24630	ENOG4105DM4	PTS System
C9I78_24635	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C9I78_24640	ENOG4105CH6	catalase
C9I78_24645	ENOG4108RXX	maleylacetoacetate isomerase
C9I78_24650	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
C9I78_24655	ENOG4108WUH	Transcriptional regulator, TetR family
C9I78_24660	ENOG4105V0I	UPF0267 protein
C9I78_24700	ENOG4105D75	Capsular exopolysaccharide family
C9I78_24720	ENOG4108IJ9	(ABC) transporter
C9I78_24725	ENOG4107FKK	extracellular solute-binding protein family 1
C9I78_24730	ENOG4105D56	permease protein
C9I78_24735	ENOG4105EG2	ABC transporter, permease
C9I78_24755	ENOG4108P3C	
C9I78_24770	ENOG4105CHR	reductase
C9I78_24795	ENOG4105NAE	bifunctional deaminase-reductase domain protein
C9I78_24805	ENOG4105CYM	Glutathione S-transferase
C9I78_24820	ENOG4105DZ1	carboxypeptidase
C9I78_24840	ENOG4105EHV	domain protein
C9I78_24845	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
C9I78_24865	ENOG4105VEQ	Cold shock protein
C9I78_24870	ENOG4105EUB	pirin domain protein
C9I78_24875	ENOG4108NRW	Phospholipase, patatin family
C9I78_24885	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
C9I78_24910	ENOG4105EP9	oxidoreductase
C9I78_24915	ENOG4105DIJ	Phosphoethanolamine transferase
C9I78_24920	ENOG41080IJ	Diacylglycerol kinase
C9I78_24930	ENOG4105JJR	Histidine kinase
C9I78_24935	ENOG4107EXC	regulatoR
C9I78_24940	ENOG4105EMU	Dehydrogenase
C9I78_24960	ENOG4108Z33	Thiol disulfide Interchange Protein
C9I78_24980	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
C9I78_24990	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
C9I78_25005	ENOG4105EST	Metal Dependent Phosphohydrolase
C9I78_25015	ENOG4105DZC	cytosine deaminase
C9I78_25020	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
C9I78_25030	ENOG4105CJW	magnesium transporter
C9I78_25035	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
C9I78_25040	ENOG4105EFX	secretion protein, HlyD family
C9I78_25065	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
C9I78_25070	ENOG4105E0F	Histidine kinase
C9I78_25085	ENOG4105DVH	amino acid
C9I78_25100	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
C9I78_25120	ENOG4105BZU	Histidine kinase
C9I78_25125	ENOG4105EE0	oxidoreductase
C9I78_25140	ENOG41090HJ	UPF0265 protein
C9I78_25155	ENOG4108YXG	UPF0502 protein
C9I78_25160	ENOG41082IR	Excinuclease ABC C subunit domain protein
C9I78_25165	ENOG4108QGH	periplasmic
C9I78_25170	ENOG4105BZU	Histidine kinase
C9I78_25180	ENOG4105EFX	secretion protein, HlyD family
C9I78_25200	ENOG4105EW9	transcriptional regulator AsnC family
C9I78_25230	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C9I78_25235	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
C9I78_25255	ENOG4105CHU	acetyl-coa acetyltransferase
C9I78_25265	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
C9I78_25275	ENOG4105CUW	cytochrome C-TYPE protein
C9I78_25285	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
C9I78_25300	ENOG4105BZU	Histidine kinase
C9I78_25305	ENOG4105WH1	Two component transcriptional regulator luxr family
C9I78_25320	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
C9I78_25325	ENOG4107YWA	deoxycytidylate deaminase
C9I78_25340	ENOG4108N3W	hemolysin secretion protein
C9I78_25345	ENOG4108YZN	class I peptide chain release factor
C9I78_25350	ENOG4107VXZ	Hydrolase
C9I78_25355	ENOG4105UYK	outer membrane protein a
C9I78_25365	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
C9I78_25370	ENOG4105DXI	Major Facilitator superfamily
C9I78_25380	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
C9I78_25385	ENOG4105CV1	Transketolase (EC 2.2.1.1)
C9I78_25390	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
C9I78_25415	ENOG4105BZU	Histidine kinase
C9I78_25420	ENOG4105KHC	sulfurtransferase
C9I78_25440	ENOG4105D06	uba thif-type nad fad binding protein
C9I78_25445	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
C9I78_25455	ENOG4105C5A	transporter
C9I78_25465	ENOG4105CMQ	Chloride channel
C9I78_25480	ENOG4107RGM	aldo keto reductase
C9I78_25485	ENOG4108UNF	response regulator
C9I78_25495	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
C9I78_25500	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
C9I78_25505	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
C9I78_25510	ENOG4105C10	Electron transfer flavoprotein
C9I78_25515	ENOG4105BZJ	Electron transfer flavoprotein
C9I78_25520	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
C9I78_25530	ENOG4105C0Z	ABC transporter
C9I78_25555	ENOG4108IV0	ABC, transporter
C9I78_25560	ENOG4105DZS	Phenylacetate-CoA ligase
C9I78_25575	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
C9I78_25580	ENOG4105DQU	oxidoreductase, subunit beta
C9I78_25585	ENOG4105G9V	cytochrome C
C9I78_25595	ENOG4105VUF	Transcriptional regulator
C9I78_25600	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
C9I78_25605	ENOG4108S58	Phenazine biosynthesis protein PhzF
C9I78_25615	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
C9I78_25620	ENOG4105C4M	(Ubiquinol oxidase) subunit I
C9I78_25625	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
C9I78_25630	ENOG4108UW5	maltose o-acetyltransferase
C9I78_25640	ENOG4105EGS	Mechanosensitive ion channel
C9I78_25655	ENOG4105BZU	Histidine kinase
C9I78_25660	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
C9I78_25670	ENOG4108IPT	Naphthoate synthase
C9I78_25675	ENOG4107QX3	carboxylase
C9I78_25680	ENOG4105C1G	acyl-Coa dehydrogenase
C9I78_25690	ENOG4105CHU	acetyl-coa acetyltransferase
C9I78_25695	ENOG4105C26	Dehydrogenase
C9I78_25700	ENOG4105C1G	acyl-Coa dehydrogenase
C9I78_25705	ENOG4105E39	Enoyl-CoA hydratase
C9I78_25715	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
C9I78_25730	ENOG4105BZU	Histidine kinase
C9I78_25735	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
C9I78_25740	ENOG4105C26	Dehydrogenase
C9I78_25745	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
C9I78_25755	ENOG4108HQS	Glycine betaine
C9I78_25760	ENOG4108IJ7	Glycine betaine
C9I78_25765	ENOG4108RCM	Nitroreductase
C9I78_25775	ENOG4107QX8	SPFH domain, Band 7 family protein
C9I78_25785	ENOG4105BZU	Histidine kinase
C9I78_25800	ENOG4105CA0	peroxidase
C9I78_25805	ENOG4105BZU	Histidine kinase
C9I78_25825	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
C9I78_25845	ENOG4105C7H	Helicase, RecD TraA family
C9I78_25865	ENOG4105D13	transposase
C9I78_25900	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
C9I78_25940	ENOG4105DFP	Integrase
C9I78_25980	ENOG4107QMH	DNA methylase
C9I78_26000	ENOG4105BZU	Histidine kinase
C9I78_26030	ENOG4108YGG	dna repair protein
C9I78_26050	ENOG4105D13	transposase
C9I78_26055	ENOG4108YGG	dna repair protein
C9I78_26150	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
C9I78_26170	ENOG4105C3F	Signal peptidase i
C9I78_26245	ENOG4107QJE	Chromosome Partitioning Protein
C9I78_26280	ENOG4107WZZ	SMC domain protein
C9I78_26305	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
C9I78_26315	ENOG4105D13	transposase
C9I78_26545	ENOG4108IYH	Dna topoisomerase
C9I78_26635	ENOG4107U4J	modification