locus-tag	class	description
C9I78_00010	COG4974	Belongs to the 'phage' integrase family
C9I78_00020	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C9I78_00030	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9I78_00035	COG0250	Participates in transcription elongation, termination and antitermination
C9I78_00040	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C9I78_00045	COG0081	regulation of translation
C9I78_00050	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C9I78_00055	COG0222	ribosome binding
C9I78_00060	COG0085	RNA polymerase activity
C9I78_00065	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C9I78_00070	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C9I78_00075	COG2816	NAD+ diphosphatase activity
C9I78_00090	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C9I78_00095	COG1573	uracil-dna glycosylase
C9I78_00100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9I78_00105	COG3068	Protein conserved in bacteria
C9I78_00110	COG1253	flavin adenine dinucleotide binding
C9I78_00125	COG0151	Belongs to the GarS family
C9I78_00135	COG0138	bifunctional purine biosynthesis protein purh
C9I78_00145	COG0789	Transcriptional regulator
C9I78_00150	COG3710	Transcriptional regulator
C9I78_00160	COG0531	amino acid
C9I78_00165	COG1982	Orn Lys Arg decarboxylase major
C9I78_00230	COG3706	GGDEF domain
C9I78_00245	COG0488	(ABC) transporter
C9I78_00250	COG2814	Major facilitator Superfamily
C9I78_00260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C9I78_00315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C9I78_00320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9I78_00325	COG2264	protein methyltransferase activity
C9I78_00335	COG0439	Biotin carboxylase
C9I78_00340	COG0511	ligase activity, forming carbon-carbon bonds
C9I78_00345	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C9I78_00350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9I78_00365	COG2814	Major facilitator Superfamily
C9I78_00370	COG0784	Response regulator, receiver
C9I78_00370	COG2205	protein histidine kinase activity
C9I78_00395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9I78_00405	COG3263	regulation of cellular component size
C9I78_00415	COG4232	protein-disulfide reductase activity
C9I78_00420	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C9I78_00425	COG1027	Aspartate ammonia-lyase
C9I78_00430	COG3030	protein affecting phage T7 exclusion by the F plasmid
C9I78_00435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C9I78_00445	COG2205	protein histidine kinase activity
C9I78_00450	COG0745	RESPONSE REGULATOR receiver
C9I78_00460	COG3678	ATP-independent chaperone mediated protein folding
C9I78_00470	COG0205	6-phosphofructokinase activity
C9I78_00475	COG0534	Mate efflux family protein
C9I78_00480	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C9I78_00485	COG0459	protein refolding
C9I78_00495	COG1285	pathogenesis
C9I78_00505	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9I78_00515	COG1509	lysine 2,3-aminomutase activity
C9I78_00520	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C9I78_00530	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C9I78_00535	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C9I78_00540	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C9I78_00545	COG1053	succinate dehydrogenase
C9I78_00555	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C9I78_00575	COG4942	peptidase
C9I78_00580	COG1045	serine acetyltransferase
C9I78_00585	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C9I78_00590	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C9I78_00595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9I78_00600	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C9I78_00615	COG0471	metal ion transport
C9I78_00620	COG0688	phosphatidylethanolamine metabolic process
C9I78_00625	COG1162	GTPase activity
C9I78_00630	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C9I78_00700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C9I78_00705	COG0802	atpase or kinase
C9I78_00715	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C9I78_00720	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C9I78_00730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C9I78_00735	COG0330	HflC and HflK could
C9I78_00740	COG0330	HflC and HflK could
C9I78_00745	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C9I78_00750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C9I78_00760	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C9I78_00765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9I78_00765	COG1017	nitric oxide dioxygenase activity
C9I78_00770	COG1959	2 iron, 2 sulfur cluster binding
C9I78_00775	COG0557	exoribonuclease II activity
C9I78_00780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9I78_00785	COG0546	phosphoglycolate phosphatase activity
C9I78_00790	COG0180	Tryptophanyl-tRNA synthetase
C9I78_00820	COG0512	Glutamine amidotransferase of anthranilate synthase
C9I78_00825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C9I78_00835	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_00845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I78_00850	COG3954	Phosphoribulokinase
C9I78_00855	COG3089	Belongs to the UPF0270 family
C9I78_00860	COG0429	hydrolase of the alpha beta-hydrolase fold
C9I78_00870	COG0488	(ABC) transporter
C9I78_00880	COG2249	NAD(P)H dehydrogenase (quinone) activity
C9I78_00895	COG1047	Peptidyl-prolyl cis-trans
C9I78_00905	COG1446	asparaginase
C9I78_00910	COG2900	Belongs to the SlyX family
C9I78_00920	COG0545	Peptidyl-prolyl cis-trans isomerase
C9I78_00925	COG2964	Protein conserved in bacteria
C9I78_00930	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C9I78_00935	COG2923	Belongs to the DsrF TusC family
C9I78_00940	COG2168	tRNA wobble position uridine thiolation
C9I78_00950	COG0049	tRNA binding
C9I78_00955	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C9I78_00960	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C9I78_00965	COG2906	2 iron, 2 sulfur cluster binding
C9I78_00975	COG0281	malic enzyme
C9I78_00985	COG0626	cystathionine gamma-synthase activity
C9I78_00990	COG0460	homoserine dehydrogenase
C9I78_00990	COG0527	aspartate kinase activity
C9I78_00995	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C9I78_01005	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C9I78_01010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9I78_01015	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C9I78_01020	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C9I78_01025	COG0137	argininosuccinate synthase activity
C9I78_01030	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C9I78_01030	COG0165	Argininosuccinate lyase
C9I78_01045	COG0678	peroxiredoxin activity
C9I78_01045	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9I78_01055	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C9I78_01085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C9I78_01090	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C9I78_01100	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C9I78_01105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C9I78_01115	COG0360	Binds together with S18 to 16S ribosomal RNA
C9I78_01120	COG2965	DNA replication, synthesis of RNA primer
C9I78_01130	COG0359	binds to the 23S rRNA
C9I78_01140	COG0305	Participates in initiation and elongation during chromosome replication
C9I78_01145	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9I78_01155	COG0432	Pfam Uncharacterised protein family UPF0047
C9I78_01160	COG0166	Belongs to the GPI family
C9I78_01170	COG0735	belongs to the Fur family
C9I78_01180	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9I78_01205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C9I78_01210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9I78_01215	COG0175	sulfate reduction
C9I78_01285	COG3335	DDE superfamily endonuclease
C9I78_01300	COG0646	methionine synthase
C9I78_01300	COG1410	methionine synthase
C9I78_01305	COG0527	aspartate kinase activity
C9I78_01315	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C9I78_01325	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C9I78_01340	COG0629	single-stranded DNA binding
C9I78_01370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9I78_01390	COG2200	EAL domain
C9I78_01390	COG2199	diguanylate cyclase activity
C9I78_01415	COG3409	Peptidoglycan-binding domain 1 protein
C9I78_01415	COG3267	Type II secretory pathway component ExeA
C9I78_01425	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9I78_01430	COG1459	type II secretion system
C9I78_01475	COG1077	Cell shape determining protein MreB Mrl
C9I78_01480	COG1792	Involved in formation and maintenance of cell shape
C9I78_01485	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C9I78_01490	COG0424	maF-like protein
C9I78_01495	COG1530	ribonuclease E activity
C9I78_01500	COG3164	Protein of unknown function
C9I78_01505	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9I78_01510	COG0312	modulator of DNA gyrase
C9I78_01515	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C9I78_01520	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C9I78_01535	COG0564	pseudouridine synthase activity
C9I78_01540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9I78_01545	COG3028	Belongs to the UPF0307 family
C9I78_01550	COG0312	modulator of DNA gyrase
C9I78_01555	COG2239	Acts as a magnesium transporter
C9I78_01560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_01565	COG1660	Displays ATPase and GTPase activities
C9I78_01570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_01575	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C9I78_01585	COG1137	ATPase activity
C9I78_01590	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C9I78_01600	COG0517	IMP dehydrogenase activity
C9I78_01600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C9I78_01610	COG1127	ABC transporter
C9I78_01615	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C9I78_01620	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C9I78_01625	COG2854	intermembrane phospholipid transfer
C9I78_01635	COG5007	Belongs to the BolA IbaG family
C9I78_01640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C9I78_01645	COG0204	Acyl-transferase
C9I78_01650	COG0251	oxidation-reduction process
C9I78_01655	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
C9I78_01660	COG0540	Belongs to the ATCase OTCase family
C9I78_01670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C9I78_01675	COG2235	arginine
C9I78_01755	COG0525	valine-tRNA ligase activity
C9I78_01760	COG2927	DNA polymerase III (CHI subunit)
C9I78_01765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C9I78_01770	COG0795	lipopolysaccharide-transporting ATPase activity
C9I78_01775	COG0795	lipopolysaccharide-transporting ATPase activity
C9I78_01785	COG4325	translation initiation factor activity
C9I78_01790	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_01805	COG0726	polysaccharide deacetylase
C9I78_01810	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9I78_01815	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C9I78_01820	COG1447	Phosphotransferase system cellobiose-specific component IIA
C9I78_01825	COG1486	melibiose metabolic process
C9I78_01830	COG3394	polysaccharide catabolic process
C9I78_01840	COG3437	response regulator, receiver
C9I78_01890	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_01920	COG0840	transmembrane signaling receptor activity
C9I78_01960	COG0741	lytic transglycosylase activity
C9I78_01965	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
C9I78_01975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C9I78_01985	COG2066	Belongs to the glutaminase family
C9I78_01990	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9I78_01995	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C9I78_02005	COG1872	DUF167
C9I78_02010	COG0762	integral membrane protein
C9I78_02015	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C9I78_02020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C9I78_02035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C9I78_02040	COG1678	Uncharacterized ACR, COG1678
C9I78_02045	COG0189	ligase activity
C9I78_02050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C9I78_02055	COG2356	endonuclease I
C9I78_02060	COG3091	SprT-like family
C9I78_02070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
C9I78_02080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C9I78_02085	COG0583	DNA-binding transcription factor activity
C9I78_02090	COG4771	TonB-dependent receptor
C9I78_02095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9I78_02100	COG0126	phosphoglycerate kinase activity
C9I78_02105	COG0191	fructose-bisphosphate aldolase activity
C9I78_02110	COG0668	transmembrane transport
C9I78_02115	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C9I78_02125	COG0583	DNA-binding transcription factor activity
C9I78_02135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9I78_02140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C9I78_02145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C9I78_02155	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
C9I78_02165	COG3079	Belongs to the UPF0149 family
C9I78_02170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9I78_02175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9I78_02190	COG0354	folic acid binding
C9I78_02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C9I78_02205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C9I78_02215	COG1595	DNA-templated transcription, initiation
C9I78_02220	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C9I78_02230	COG3086	response to oxidative stress
C9I78_02235	COG0481	GTPase activity
C9I78_02240	COG0681	Belongs to the peptidase S26 family
C9I78_02245	COG0571	ribonuclease III activity
C9I78_02250	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C9I78_02255	COG1381	Involved in DNA repair and RecF pathway recombination
C9I78_02260	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C9I78_02265	COG0736	holo-[acyl-carrier-protein] synthase activity
C9I78_02280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9I78_02290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9I78_02295	COG3956	TIGRFAM MazG family protein
C9I78_02300	COG0504	CTP synthase activity
C9I78_02305	COG0148	phosphopyruvate hydratase activity
C9I78_02310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C9I78_02315	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C9I78_02320	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
C9I78_02325	COG0585	pseudouridine synthase activity
C9I78_02330	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C9I78_02335	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C9I78_02350	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C9I78_02355	COG1546	Belongs to the CinA family
C9I78_02365	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C9I78_02430	COG2137	regulation of response to DNA damage stimulus
C9I78_02435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C9I78_02440	COG0527	aspartate kinase activity
C9I78_02500	COG3630	sodium ion export across plasma membrane
C9I78_02505	COG5016	pyruvate
C9I78_02505	COG0511	ligase activity, forming carbon-carbon bonds
C9I78_02510	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
C9I78_02515	COG1063	alcohol dehydrogenase
C9I78_02520	COG1238	metal cluster binding
C9I78_02525	COG0612	Peptidase, M16
C9I78_02530	COG2918	glutathione biosynthetic process
C9I78_02540	COG1854	S-ribosylhomocysteine lyase activity
C9I78_02545	COG4536	flavin adenine dinucleotide binding
C9I78_02550	COG4137	Cytochrome C assembly protein
C9I78_02555	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C9I78_02560	COG0228	four-way junction DNA binding
C9I78_02565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C9I78_02580	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C9I78_02585	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C9I78_02590	COG0237	dephospho-CoA kinase activity
C9I78_02600	COG1459	type II secretion system
C9I78_02605	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9I78_02615	COG0157	Belongs to the NadC ModD family
C9I78_02625	COG2186	Transcriptional regulator
C9I78_02630	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C9I78_02635	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9I78_02640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9I78_02655	COG0288	reversible hydration of carbon dioxide
C9I78_02660	COG0659	secondary active sulfate transmembrane transporter activity
C9I78_02670	COG1131	(ABC) transporter
C9I78_02675	COG0842	Transport permease protein
C9I78_02685	COG1560	Kdo2-lipid A biosynthetic process
C9I78_02695	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C9I78_02700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C9I78_02705	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C9I78_02720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9I78_02730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9I78_02735	COG1489	DNA binding
C9I78_02775	COG3550	peptidyl-serine autophosphorylation
C9I78_02845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9I78_02850	COG1752	Esterase of the alpha-beta hydrolase superfamily
C9I78_02855	COG1049	propionate catabolic process, 2-methylcitrate cycle
C9I78_02860	COG3112	Uncharacterised protein family (UPF0231)
C9I78_02870	COG0004	ammonium transporteR
C9I78_02875	COG1840	ABC-type Fe3 transport system, periplasmic component
C9I78_02885	COG3842	ATPase activity
C9I78_02890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9I78_02905	COG2971	BadF BadG BcrA BcrD
C9I78_02915	COG4608	Belongs to the ABC transporter superfamily
C9I78_02920	COG0444	Belongs to the ABC transporter superfamily
C9I78_02925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9I78_02935	COG0747	negative chemotaxis
C9I78_02940	COG0784	Response regulator, receiver
C9I78_02940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_02940	COG2205	protein histidine kinase activity
C9I78_02940	COG2198	Histidine kinase
C9I78_02950	COG2813	Specifically methylates the guanine in position
C9I78_02955	COG0628	permease
C9I78_02960	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C9I78_02965	COG0316	Belongs to the HesB IscA family
C9I78_02975	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_02980	COG0739	heme binding
C9I78_02985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C9I78_02995	COG2027	D-alanyl-D-alanine carboxypeptidase
C9I78_03000	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C9I78_03005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9I78_03010	COG1534	Rna-binding protein
C9I78_03015	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C9I78_03020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C9I78_03025	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C9I78_03030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9I78_03040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C9I78_03055	COG0779	Required for maturation of 30S ribosomal subunits
C9I78_03060	COG0195	Participates in both transcription termination and antitermination
C9I78_03065	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C9I78_03070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C9I78_03075	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C9I78_03080	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C9I78_03085	COG1185	polyribonucleotide nucleotidyltransferase activity
C9I78_03090	COG4785	May be involved in cell division
C9I78_03100	COG0534	Mate efflux family protein
C9I78_03125	COG3153	acetyltransferase
C9I78_03145	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C9I78_03155	COG0084	hydrolase, TatD family'
C9I78_03160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9I78_03165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C9I78_03170	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C9I78_03175	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C9I78_03180	COG0813	purine-nucleoside phosphorylase activity
C9I78_03190	COG0560	Phosphoserine phosphatase
C9I78_03200	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C9I78_03205	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C9I78_03210	COG0583	DNA-binding transcription factor activity
C9I78_03225	COG2169	Transcriptional regulator
C9I78_03250	COG4964	Belongs to the GSP D family
C9I78_03310	COG0583	DNA-binding transcription factor activity
C9I78_03315	COG0531	amino acid
C9I78_03320	COG2731	YhcH YjgK YiaL family protein
C9I78_03325	COG3250	beta-galactosidase activity
C9I78_03330	COG1609	Transcriptional regulator
C9I78_03340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C9I78_03350	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C9I78_03355	COG2017	converts alpha-aldose to the beta-anomer
C9I78_03370	COG2211	Major facilitator Superfamily
C9I78_03375	COG1609	Transcriptional regulator
C9I78_03380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9I78_03395	COG0598	Magnesium transport protein CorA
C9I78_03400	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C9I78_03405	COG1349	DNA-binding transcription factor activity
C9I78_03410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C9I78_03415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C9I78_03430	COG2271	Major facilitator Superfamily
C9I78_03435	COG0584	glycerophosphoryl diester phosphodiesterase
C9I78_03440	COG2171	N-acyltransferase activity
C9I78_03445	COG3141	response to X-ray
C9I78_03465	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C9I78_03475	COG1074	ATP-dependent DNA helicase activity
C9I78_03480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9I78_03490	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C9I78_03490	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C9I78_03505	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C9I78_03510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C9I78_03515	COG2166	iron-sulfur cluster assembly
C9I78_03520	COG3706	GGDEF domain
C9I78_03525	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C9I78_03530	COG0693	protein deglycase activity
C9I78_03535	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C9I78_03560	COG1595	DNA-templated transcription, initiation
C9I78_03580	COG3056	Lipoprotein
C9I78_03585	COG2813	Specifically methylates the guanine in position
C9I78_03590	COG0271	Belongs to the BolA IbaG family
C9I78_03600	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C9I78_03605	COG1805	sodium ion transport
C9I78_03610	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C9I78_03615	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C9I78_03620	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C9I78_03625	COG2871	sodium ion transport
C9I78_03630	COG1477	protein flavinylation
C9I78_03645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9I78_03650	COG0514	ATP-dependent DNA helicase (RecQ)
C9I78_03670	COG0733	neurotransmitter:sodium symporter activity
C9I78_03690	COG0442	prolyl-tRNA aminoacylation
C9I78_03695	COG1720	tRNA m6t6A37 methyltransferase activity
C9I78_03700	COG0254	rRNA binding
C9I78_03715	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C9I78_03720	COG1671	Belongs to the UPF0178 family
C9I78_03745	COG3098	single-species biofilm formation
C9I78_03750	COG0564	pseudouridine synthase activity
C9I78_03760	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C9I78_03765	COG0024	Methionine aminopeptidase
C9I78_03770	COG0052	Belongs to the universal ribosomal protein uS2 family
C9I78_03775	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C9I78_03780	COG0528	UMP kinase activity
C9I78_03785	COG0233	cytoplasmic translational termination
C9I78_03790	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C9I78_03795	COG0575	Belongs to the CDS family
C9I78_03800	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C9I78_03805	COG0750	zinc metalloprotease
C9I78_03815	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
C9I78_03820	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I78_03825	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C9I78_03830	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I78_03835	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I78_03840	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C9I78_03845	COG0587	DNA-directed DNA polymerase activity
C9I78_03850	COG0825	malonyl-CoA metabolic process
C9I78_03855	COG0037	tRNA processing
C9I78_03865	COG0347	Belongs to the P(II) protein family
C9I78_03870	COG3021	interspecies interaction between organisms
C9I78_03880	COG0741	lytic transglycosylase activity
C9I78_03880	COG1388	LysM domain
C9I78_03885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9I78_03890	COG2226	methyltransferase
C9I78_03895	COG0328	RNA-DNA hybrid ribonuclease activity
C9I78_03900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9I78_03930	COG1960	acyl-CoA dehydrogenase activity
C9I78_03935	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C9I78_03940	COG0121	glutamine amidotransferase
C9I78_03945	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C9I78_03950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C9I78_03955	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C9I78_03960	COG2233	PERMEase
C9I78_03980	COG1393	Belongs to the ArsC family
C9I78_03985	COG4783	chaperone-mediated protein folding
C9I78_04000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C9I78_04005	COG2716	regulation of RNA biosynthetic process
C9I78_04010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C9I78_04030	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9I78_04035	COG1393	Belongs to the ArsC family
C9I78_04065	COG2837	iron assimilation
C9I78_04070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_04080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_04085	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_04090	COG1334	flagellar protein FlaG
C9I78_04095	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C9I78_04105	COG1516	flagellar protein fliS
C9I78_04115	COG4191	Histidine kinase
C9I78_04120	COG2204	response regulator
C9I78_04125	COG1677	Flagellar hook-basal body complex protein FliE
C9I78_04135	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9I78_04185	COG1987	bacterial-type flagellum assembly
C9I78_04210	COG0455	bacterial-type flagellum organization
C9I78_04225	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C9I78_04230	COG2198	Histidine kinase
C9I78_04230	COG0643	Histidine kinase
C9I78_04235	COG2201	protein-glutamate methylesterase activity
C9I78_04240	COG1192	Involved in chromosome partitioning
C9I78_04250	COG0835	chemotaxis
C9I78_04260	COG4133	protoheme IX ABC transporter activity
C9I78_04265	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9I78_04270	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9I78_04275	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C9I78_04280	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C9I78_04285	COG1138	Cytochrome C-type biogenesis protein
C9I78_04290	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C9I78_04305	COG2853	Lipoprotein
C9I78_04315	COG2067	long-chain fatty acid transport protein
C9I78_04335	COG0183	Belongs to the thiolase family
C9I78_04340	COG1024	Enoyl-CoA hydratase
C9I78_04340	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9I78_04355	COG2062	phosphohistidine phosphatase, SixA
C9I78_04360	COG2840	Smr protein MutS2
C9I78_04365	COG2890	protein-(glutamine-N5) methyltransferase activity
C9I78_04370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C9I78_04375	COG2860	membrane
C9I78_04385	COG3101	peptidyl-lysine hydroxylation
C9I78_04400	COG0431	NADPH-dependent FMN reductase
C9I78_04405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9I78_04405	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C9I78_04410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9I78_04420	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C9I78_04425	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C9I78_04435	COG0101	tRNA pseudouridine synthase activity
C9I78_04440	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C9I78_04445	COG0285	dihydrofolate synthase activity
C9I78_04450	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C9I78_04455	COG1286	toxin biosynthetic process
C9I78_04460	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C9I78_04465	COG0583	DNA-binding transcription factor activity
C9I78_04470	COG0745	RESPONSE REGULATOR receiver
C9I78_04480	COG2832	Protein of unknown function (DUF454)
C9I78_04485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C9I78_04495	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C9I78_04500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C9I78_04505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C9I78_04510	COG0814	amino acid
C9I78_04515	COG0251	oxidation-reduction process
C9I78_04520	COG3681	Belongs to the UPF0597 family
C9I78_04535	COG2261	transglycosylase associated protein
C9I78_04540	COG2983	Belongs to the UPF0260 family
C9I78_04545	COG0668	transmembrane transport
C9I78_04550	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C9I78_04555	COG0346	lactoylglutathione lyase activity
C9I78_04565	COG1785	Belongs to the alkaline phosphatase family
C9I78_04585	COG2226	methyltransferase
C9I78_04600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9I78_04605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_04615	COG3139	Protein of unknown function (DUF1315)
C9I78_04620	COG0252	asparaginase activity
C9I78_04625	COG0616	signal peptide processing
C9I78_04630	COG0446	pyridine nucleotide-disulphide oxidoreductase
C9I78_04630	COG1902	pentaerythritol trinitrate reductase activity
C9I78_04635	COG0778	Nitroreductase
C9I78_04640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C9I78_04660	COG0123	including yeast histone deacetylase and acetoin utilization protein
C9I78_04670	COG3083	sulfuric ester hydrolase activity
C9I78_04675	COG3082	Protein of unknown function (DUF1414)
C9I78_04680	COG3081	Nucleoid-associated protein
C9I78_04695	COG1757	Na H antiporter
C9I78_04700	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C9I78_04705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I78_04710	COG2095	MarC family integral membrane protein
C9I78_04715	COG1454	alcohol dehydrogenase
C9I78_04715	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_04735	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C9I78_04745	COG2056	Na+-H+ antiporter family
C9I78_04750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C9I78_04765	COG2885	chlorophyll binding
C9I78_04775	COG0346	lactoylglutathione lyase activity
C9I78_04780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C9I78_04785	COG4660	Part of a membrane complex involved in electron transport
C9I78_04790	COG4659	FMN binding
C9I78_04795	COG4658	electron transport chain
C9I78_04800	COG4656	Part of a membrane complex involved in electron transport
C9I78_04805	COG2878	Part of a membrane complex involved in electron transport
C9I78_04810	COG4657	Part of a membrane complex involved in electron transport
C9I78_04825	COG0556	nucleotide-excision repair
C9I78_04830	COG2204	response regulator
C9I78_04835	COG2198	Histidine kinase
C9I78_04840	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C9I78_04845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C9I78_04850	COG0521	Mo-molybdopterin cofactor biosynthetic process
C9I78_04855	COG0315	cyclic pyranopterin monophosphate synthase activity
C9I78_04860	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C9I78_04865	COG0314	molybdopterin synthase activity
C9I78_04875	COG0601	transmembrane transport
C9I78_04880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9I78_04885	COG0444	Belongs to the ABC transporter superfamily
C9I78_04895	COG0435	Glutathione S-transferase
C9I78_04905	COG3174	membrane
C9I78_04910	COG0280	phosphate acetyltransferase
C9I78_04910	COG0857	belongs to the CobB CobQ family
C9I78_04915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C9I78_04920	COG3092	negative regulation of chromosome organization
C9I78_04930	COG4120	Belongs to the binding-protein-dependent transport system permease family
C9I78_04935	COG1122	ATPase activity
C9I78_04940	COG0366	Alpha amylase catalytic
C9I78_04945	COG0745	RESPONSE REGULATOR receiver
C9I78_04945	COG3706	GGDEF domain
C9I78_04950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C9I78_04955	COG0653	protein targeting
C9I78_04960	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C9I78_04965	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C9I78_04970	COG2186	Transcriptional regulator
C9I78_04980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9I78_04980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9I78_04985	COG0489	protein tyrosine kinase activity
C9I78_04990	COG0572	uridine kinase
C9I78_05000	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
C9I78_05005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C9I78_05010	COG0659	secondary active sulfate transmembrane transporter activity
C9I78_05020	COG1530	ribonuclease E activity
C9I78_05035	COG0564	pseudouridine synthase activity
C9I78_05040	COG0424	maF-like protein
C9I78_05045	COG1399	metal-binding, possibly nucleic acid-binding protein
C9I78_05055	COG0416	fatty acid biosynthetic process
C9I78_05060	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9I78_05090	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C9I78_05095	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C9I78_05105	COG0084	hydrolase, TatD family'
C9I78_05110	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9I78_05110	COG1263	PTS System
C9I78_05130	COG0733	neurotransmitter:sodium symporter activity
C9I78_05145	COG4667	esterase of the alpha-beta hydrolase superfamily
C9I78_05150	COG0469	pyruvate kinase activity
C9I78_05155	COG1940	carbohydrate kinase activity
C9I78_05160	COG0835	chemotaxis
C9I78_05160	COG0784	Response regulator, receiver
C9I78_05165	COG0587	DNA-directed DNA polymerase activity
C9I78_05180	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_05185	COG0616	signal peptide processing
C9I78_05190	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C9I78_05195	COG0539	negative regulation of cytoplasmic translation
C9I78_05205	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
C9I78_05210	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C9I78_05215	COG0284	orotidine-5'-phosphate decarboxylase activity
C9I78_05220	COG4166	transmembrane transport
C9I78_05245	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C9I78_05255	COG3008	intermembrane lipid transfer
C9I78_05255	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C9I78_05260	COG2995	paraquat-inducible protein a
C9I78_05265	COG3258	Cytochrome c
C9I78_05270	COG2863	cytochrome
C9I78_05310	COG4232	protein-disulfide reductase activity
C9I78_05315	COG3118	belongs to the thioredoxin family
C9I78_05345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_05355	COG1136	(ABC) transporter
C9I78_05355	COG0577	efflux transmembrane transporter activity
C9I78_05360	COG0577	efflux transmembrane transporter activity
C9I78_05360	COG1136	(ABC) transporter
C9I78_05365	COG0577	efflux transmembrane transporter activity
C9I78_05365	COG1136	(ABC) transporter
C9I78_05370	COG1335	isochorismatase
C9I78_05385	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C9I78_05420	COG5002	protein histidine kinase activity
C9I78_05420	COG3850	Histidine kinase
C9I78_05425	COG0745	RESPONSE REGULATOR receiver
C9I78_05435	COG0840	transmembrane signaling receptor activity
C9I78_05440	COG1032	radical SAM domain protein
C9I78_05445	COG2203	Gaf domain
C9I78_05445	COG5001	Diguanylate cyclase
C9I78_05445	COG3706	GGDEF domain
C9I78_05445	COG4251	negative regulation of phosphorylation
C9I78_05460	COG0583	DNA-binding transcription factor activity
C9I78_05470	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C9I78_05480	COG2350	Protein conserved in bacteria
C9I78_05485	COG1607	acyl-coa hydrolase
C9I78_05490	COG2917	probably involved in intracellular septation
C9I78_05510	COG1301	dicarboxylic acid transport
C9I78_05520	COG0318	PFAM AMP-dependent synthetase and ligase
C9I78_05525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I78_05530	COG0159	tryptophan synthase activity
C9I78_05535	COG0133	tryptophan synthase activity
C9I78_05540	COG0135	phosphoribosylanthranilate isomerase activity
C9I78_05540	COG0134	indole-3-glycerol-phosphate synthase activity
C9I78_05545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C9I78_05550	COG0512	Glutamine amidotransferase of anthranilate synthase
C9I78_05555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9I78_05565	COG0613	PHP domain protein
C9I78_05570	COG0009	L-threonylcarbamoyladenylate synthase
C9I78_05580	COG1187	pseudouridine synthase activity
C9I78_05590	COG3099	Belongs to the UPF0263 family
C9I78_05595	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C9I78_05605	COG0417	DNA replication proofreading
C9I78_05610	COG2197	response regulator
C9I78_05615	COG0322	excinuclease ABC activity
C9I78_05655	COG0019	diaminopimelate decarboxylase activity
C9I78_05680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9I78_05685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C9I78_05690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9I78_05710	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C9I78_05720	COG0437	4 iron, 4 sulfur cluster binding
C9I78_05725	COG3301	Polysulphide reductase, NrfD
C9I78_05730	COG1138	Cytochrome C-type biogenesis protein
C9I78_05740	COG4235	cytochrome complex assembly
C9I78_05740	COG3088	subunit of a heme lyase
C9I78_05750	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C9I78_05775	COG2989	Protein conserved in bacteria
C9I78_05780	COG3108	Peptidase M15
C9I78_05785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C9I78_05800	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
C9I78_05825	COG1846	Transcriptional regulator
C9I78_05830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9I78_05835	COG0840	transmembrane signaling receptor activity
C9I78_05855	COG1448	Aminotransferase
C9I78_05880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I78_05890	COG0017	Asparaginyl-tRNA synthetase
C9I78_05900	COG0720	synthase
C9I78_05910	COG2200	EAL domain
C9I78_05915	COG1760	l-serine dehydratase
C9I78_05920	COG0814	amino acid
C9I78_05925	COG0494	nUDIX hydrolase
C9I78_05940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C9I78_05960	COG3106	COG3106 Predicted ATPase
C9I78_05965	COG3768	UPF0283 membrane protein
C9I78_05975	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9I78_06015	COG2801	Transposase and inactivated derivatives
C9I78_06115	COG2732	(Barnase) inhibitor
C9I78_06155	COG0346	lactoylglutathione lyase activity
C9I78_06450	COG0346	lactoylglutathione lyase activity
C9I78_06660	COG2161	toxin-antitoxin pair type II binding
C9I78_06665	COG4115	mRNA cleavage
C9I78_06730	COG1757	Na H antiporter
C9I78_06735	COG0174	glutamine synthetase
C9I78_06745	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C9I78_06750	COG1396	sequence-specific DNA binding
C9I78_06750	COG1917	Cupin 2, conserved barrel domain protein
C9I78_06755	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_06760	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9I78_06770	COG2957	Belongs to the agmatine deiminase family
C9I78_06775	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_06780	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9I78_06785	COG1227	inorganic diphosphatase activity
C9I78_06795	COG2771	luxR family
C9I78_06795	COG2200	EAL domain
C9I78_06820	COG1846	Transcriptional regulator
C9I78_06825	COG2315	Protein conserved in bacteria
C9I78_06845	COG0110	maltose O-acetyltransferase activity
C9I78_06875	COG3063	Type IV pilus biogenesis stability protein PilW
C9I78_06880	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C9I78_06895	COG0531	amino acid
C9I78_06905	COG1560	Kdo2-lipid A biosynthetic process
C9I78_06910	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C9I78_06915	COG1280	lysine exporter protein (LysE YggA)
C9I78_06925	COG1115	amino acid carrier protein
C9I78_06950	COG1368	sulfuric ester hydrolase activity
C9I78_06955	COG0642	Histidine kinase
C9I78_06960	COG0745	RESPONSE REGULATOR receiver
C9I78_06970	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_06980	COG1022	Amp-dependent synthetase and ligase
C9I78_06990	COG2113	Glycine betaine
C9I78_06995	COG4176	ABC-type proline glycine betaine transport system permease component
C9I78_07015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9I78_07020	COG0456	acetyltransferase
C9I78_07025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C9I78_07030	COG0662	Cupin 2, conserved barrel domain protein
C9I78_07035	COG0527	aspartate kinase activity
C9I78_07050	COG1858	cytochrome C peroxidase
C9I78_07065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_07080	COG3290	protein histidine kinase activity
C9I78_07085	COG4565	transcriptional regulatory protein
C9I78_07090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
C9I78_07095	COG0363	glucosamine-6-phosphate deaminase activity
C9I78_07100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
C9I78_07115	COG3284	Transcriptional regulator
C9I78_07120	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_07190	COG4669	(LipO)protein
C9I78_07210	COG3177	Filamentation induced by cAMP protein fic
C9I78_07260	COG4792	protein secretion
C9I78_07265	COG4791	protein targeting
C9I78_07270	COG4794	Type iii secretion
C9I78_07275	COG4790	Type iii secretion
C9I78_07280	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9I78_07345	COG0457	Tetratricopeptide repeat
C9I78_07365	COG0730	response to heat
C9I78_07395	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C9I78_07400	COG0372	Belongs to the citrate synthase family
C9I78_07410	COG2828	Protein conserved in bacteria
C9I78_07420	COG0456	acetyltransferase
C9I78_07435	COG0561	phosphatase activity
C9I78_07440	COG0602	queuosine metabolic process
C9I78_07445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C9I78_07450	COG3706	GGDEF domain
C9I78_07490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C9I78_07495	COG0840	transmembrane signaling receptor activity
C9I78_07500	COG1254	Belongs to the acylphosphatase family
C9I78_07505	COG2920	part of a sulfur-relay system
C9I78_07515	COG0670	Belongs to the BI1 family
C9I78_07520	COG1126	abc transporter atp-binding protein
C9I78_07525	COG0765	amino acid transport
C9I78_07530	COG4597	amino acid ABC transporter
C9I78_07535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_07555	COG1666	GTP binding
C9I78_07560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9I78_07580	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C9I78_07580	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C9I78_07590	COG3008	intermembrane lipid transfer
C9I78_07595	COG2995	paraquat-inducible protein a
C9I78_07600	COG1132	(ABC) transporter
C9I78_07605	COG1956	GAF domain-containing protein
C9I78_07610	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C9I78_07625	COG0308	aminopeptidase N
C9I78_07635	COG2902	Dehydrogenase
C9I78_07640	COG0167	dihydroorotate dehydrogenase activity
C9I78_07655	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C9I78_07655	COG0116	Belongs to the methyltransferase superfamily
C9I78_07680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C9I78_07685	COG1067	ATP-dependent peptidase activity
C9I78_07690	COG3120	sequence-specific DNA binding
C9I78_07845	COG3278	Belongs to the heme-copper respiratory oxidase family
C9I78_07860	COG2010	Cytochrome c
C9I78_07870	COG2217	Heavy metal translocating P-type atpase
C9I78_07885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C9I78_07890	COG0589	response to stress
C9I78_07900	COG0037	tRNA processing
C9I78_07920	COG3842	ATPase activity
C9I78_07925	COG1176	ABC-type spermidine putrescine transport system, permease component I
C9I78_07930	COG1177	transmembrane transport
C9I78_07935	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C9I78_07940	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C9I78_07945	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C9I78_07955	COG0004	ammonium transporteR
C9I78_08010	COG0437	4 iron, 4 sulfur cluster binding
C9I78_08015	COG3383	formate dehydrogenase (NAD+) activity
C9I78_08015	COG0243	molybdopterin cofactor binding
C9I78_08025	COG3381	protein complex oligomerization
C9I78_08050	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C9I78_08055	COG0488	(ABC) transporter
C9I78_08065	COG4191	Histidine kinase
C9I78_08070	COG2204	response regulator
C9I78_08090	COG3842	ATPase activity
C9I78_08095	COG0746	molybdenum cofactor guanylyltransferase activity
C9I78_08100	COG0303	'Molybdopterin
C9I78_08110	COG1940	carbohydrate kinase activity
C9I78_08150	COG3290	protein histidine kinase activity
C9I78_08150	COG0840	transmembrane signaling receptor activity
C9I78_08155	COG0791	NLP P60 protein
C9I78_08165	COG3706	GGDEF domain
C9I78_08170	COG2201	protein-glutamate methylesterase activity
C9I78_08185	COG0307	riboflavin synthase, alpha
C9I78_08190	COG0534	Mate efflux family protein
C9I78_08200	COG1793	dna ligase
C9I78_08235	COG2204	response regulator
C9I78_08280	COG0438	transferase activity, transferring glycosyl groups
C9I78_08285	COG1215	transferase activity, transferring glycosyl groups
C9I78_08290	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C9I78_08300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9I78_08315	COG1643	Atp-dependent helicase
C9I78_08320	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C9I78_08330	COG3381	protein complex oligomerization
C9I78_08335	COG3302	dmso reductase anchor subunit
C9I78_08340	COG0437	4 iron, 4 sulfur cluster binding
C9I78_08345	COG0243	molybdopterin cofactor binding
C9I78_08375	COG3706	GGDEF domain
C9I78_08385	COG0443	Heat shock 70 kDa protein
C9I78_08390	COG0443	Heat shock 70 kDa protein
C9I78_08420	COG1132	(ABC) transporter
C9I78_08425	COG1132	(ABC) transporter
C9I78_08450	COG0814	amino acid
C9I78_08465	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C9I78_08560	COG1522	sequence-specific DNA binding
C9I78_08595	COG0515	serine threonine protein kinase
C9I78_08620	COG3501	Rhs element vgr protein
C9I78_08640	COG2885	chlorophyll binding
C9I78_08660	COG0739	heme binding
C9I78_08670	COG0861	Integral membrane protein TerC family
C9I78_08680	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9I78_08685	COG1328	CTP reductase activity
C9I78_08690	COG1280	lysine exporter protein (LysE YggA)
C9I78_08700	COG5001	Diguanylate cyclase
C9I78_08700	COG3300	MHYT domain
C9I78_08710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_08710	COG4191	Histidine kinase
C9I78_08715	COG0471	metal ion transport
C9I78_08750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C9I78_08755	COG0583	DNA-binding transcription factor activity
C9I78_08770	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C9I78_08775	COG1982	Orn Lys Arg decarboxylase major
C9I78_08780	COG1982	Orn Lys Arg decarboxylase major
C9I78_08785	COG0531	amino acid
C9I78_08795	COG0531	amino acid
C9I78_08825	COG3264	Mechanosensitive ion channel
C9I78_08825	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C9I78_08840	COG1127	ABC transporter
C9I78_08845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C9I78_08885	COG0625	glutathione transferase activity
C9I78_08895	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C9I78_08910	COG2195	Cleaves the N-terminal amino acid of tripeptides
C9I78_08920	COG0601	transmembrane transport
C9I78_08925	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9I78_08930	COG0444	Belongs to the ABC transporter superfamily
C9I78_08950	COG3291	Pkd domain containing protein
C9I78_08965	COG1177	transmembrane transport
C9I78_08970	COG1176	ABC-type spermidine putrescine transport system, permease component I
C9I78_08975	COG3842	ATPase activity
C9I78_08980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C9I78_08985	COG2423	ornithine cyclodeaminase activity
C9I78_09005	COG3938	Belongs to the proline racemase family
C9I78_09035	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C9I78_09040	COG1451	nucleotide metabolic process
C9I78_09045	COG3475	LICD family
C9I78_09050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C9I78_09055	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C9I78_09075	COG0583	DNA-binding transcription factor activity
C9I78_09095	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
C9I78_09100	COG4139	cobalamin transport
C9I78_09105	COG2988	succinylglutamate desuccinylase activity
C9I78_09120	COG2062	phosphohistidine phosphatase, SixA
C9I78_09130	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
C9I78_09135	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C9I78_09140	COG0702	epimerase
C9I78_09150	COG2925	Exonuclease
C9I78_09155	COG1380	Effector of murein hydrolase LrgA
C9I78_09160	COG1346	cytolysis
C9I78_09165	COG0295	cytidine deaminase activity
C9I78_09170	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C9I78_09175	COG0500	methyltransferase
C9I78_09185	COG0776	regulation of translation
C9I78_09200	COG0072	phenylalanine-tRNA ligase activity
C9I78_09200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C9I78_09205	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C9I78_09210	COG3706	GGDEF domain
C9I78_09240	COG0393	Putative heavy-metal-binding
C9I78_09250	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C9I78_09260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C9I78_09275	COG2188	Transcriptional regulator
C9I78_09280	COG1228	amidohydrolase
C9I78_09285	COG0010	Belongs to the arginase family
C9I78_09290	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C9I78_09295	COG2986	histidine ammonia-lyase
C9I78_09310	COG0247	lactate metabolic process
C9I78_09310	COG0277	FAD linked oxidase domain protein
C9I78_09345	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C9I78_09360	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
C9I78_09365	COG1643	Atp-dependent helicase
C9I78_09370	COG0281	malic enzyme
C9I78_09375	COG2949	membrane
C9I78_09380	COG0471	metal ion transport
C9I78_09385	COG0745	RESPONSE REGULATOR receiver
C9I78_09385	COG3706	GGDEF domain
C9I78_09405	COG0492	ferredoxin-NADP+ reductase activity
C9I78_09410	COG4988	ABC transporter
C9I78_09415	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C9I78_09420	COG3048	D-serine ammonia-lyase activity
C9I78_09425	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C9I78_09435	COG4191	Histidine kinase
C9I78_09435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_09450	COG3070	regulator of competence-specific genes
C9I78_09470	COG2431	L-lysine efflux transmembrane transporter activity
C9I78_09480	COG0076	glutamate decarboxylase activity
C9I78_09485	COG1737	Transcriptional regulator
C9I78_09500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9I78_09505	COG2985	domain, Protein
C9I78_09505	COG3273	potassium ion transport
C9I78_09510	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C9I78_09525	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C9I78_09540	COG4181	ATPase activity
C9I78_09545	COG0534	Mate efflux family protein
C9I78_09550	COG0702	epimerase
C9I78_09555	COG3005	denitrification pathway
C9I78_09585	COG2814	Major facilitator Superfamily
C9I78_09590	COG1187	pseudouridine synthase activity
C9I78_09595	COG1061	Type III restriction enzyme res subunit
C9I78_09605	COG0745	RESPONSE REGULATOR receiver
C9I78_09610	COG2205	protein histidine kinase activity
C9I78_09615	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C9I78_09645	COG3313	Fe-S protein
C9I78_09670	COG0493	'glutamate synthase
C9I78_09680	COG0398	Pfam SNARE associated Golgi protein
C9I78_09685	COG4134	Bacterial extracellular solute-binding protein
C9I78_09690	COG4135	transport system, permease component
C9I78_09695	COG4136	ATPase activity
C9I78_09700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C9I78_09715	COG3604	Transcriptional regulator
C9I78_09720	COG1151	hydroxylamine reductase activity
C9I78_09725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9I78_09735	COG0564	pseudouridine synthase activity
C9I78_09745	COG0733	neurotransmitter:sodium symporter activity
C9I78_09755	COG0626	cystathionine gamma-synthase activity
C9I78_09760	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C9I78_09765	COG5380	lipid catabolic process
C9I78_09770	COG2818	Glycosylase
C9I78_09785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_09790	COG1983	PspC domain protein
C9I78_09800	COG1842	Phage shock protein A
C9I78_09805	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C9I78_09815	COG4168	peptide transport system, permease
C9I78_09820	COG4171	peptide transport system, permease
C9I78_09830	COG4172	Belongs to the ABC transporter superfamily
C9I78_09840	COG1227	inorganic diphosphatase activity
C9I78_09855	COG0243	molybdopterin cofactor binding
C9I78_09860	COG3005	denitrification pathway
C9I78_09865	COG4459	periplasmic nitrate reductase
C9I78_09870	COG0390	transport system, permease component
C9I78_09880	COG2116	formate transmembrane transporter activity
C9I78_09905	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C9I78_09910	COG1435	thymidine kinase activity
C9I78_09915	COG0215	cysteine-tRNA ligase activity
C9I78_09920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C9I78_09925	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C9I78_09930	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C9I78_09940	COG3012	SEC-C Motif Domain Protein
C9I78_09945	COG0140	phosphoribosyl-ATP diphosphatase activity
C9I78_09945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C9I78_09950	COG0107	imidazoleglycerol-phosphate synthase activity
C9I78_09955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C9I78_09960	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C9I78_09965	COG0131	Imidazoleglycerol-phosphate dehydratase
C9I78_09965	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C9I78_09970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C9I78_09975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C9I78_09980	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C9I78_09995	COG1757	Na H antiporter
C9I78_10005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I78_10015	COG0482	sulfurtransferase activity
C9I78_10020	COG2915	High frequency lysogenization protein hflD homolog
C9I78_10025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C9I78_10050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C9I78_10065	COG0300	oxidoreductase activity
C9I78_10075	COG0501	Belongs to the peptidase M48B family
C9I78_10085	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C9I78_10095	COG0156	8-amino-7-oxononanoate synthase activity
C9I78_10100	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C9I78_10105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9I78_10110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C9I78_10125	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C9I78_10130	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C9I78_10135	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C9I78_10140	COG1674	ftsk spoiiie
C9I78_10150	COG0686	Belongs to the AlaDH PNT family
C9I78_10160	COG0583	DNA-binding transcription factor activity
C9I78_10175	COG3568	Endonuclease Exonuclease Phosphatase
C9I78_10205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_10210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_10225	COG0840	transmembrane signaling receptor activity
C9I78_10280	COG0784	Response regulator, receiver
C9I78_10280	COG5002	protein histidine kinase activity
C9I78_10290	COG0754	glutathionylspermidine amidase activity
C9I78_10300	COG3766	membrane
C9I78_10310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C9I78_10315	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C9I78_10320	COG2885	chlorophyll binding
C9I78_10325	COG0823	Involved in the tonB-independent uptake of proteins
C9I78_10340	COG0811	peptide transport
C9I78_10345	COG0824	Thioesterase
C9I78_10355	COG4890	Cyd operon protein YbgT
C9I78_10360	COG1294	oxidase, subunit
C9I78_10365	COG1271	oxidase subunit
C9I78_10370	COG2255	four-way junction helicase activity
C9I78_10375	COG0632	four-way junction helicase activity
C9I78_10380	COG0840	transmembrane signaling receptor activity
C9I78_10385	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C9I78_10390	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C9I78_10395	COG1801	Protein of unknown function DUF72
C9I78_10400	COG4106	trans-aconitate 2-methyltransferase activity
C9I78_10405	COG0500	methyltransferase
C9I78_10415	COG0189	ligase activity
C9I78_10415	COG4067	protein conserved in archaea
C9I78_10435	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C9I78_10440	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C9I78_10445	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
C9I78_10450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9I78_10455	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C9I78_10460	COG0745	RESPONSE REGULATOR receiver
C9I78_10465	COG3381	protein complex oligomerization
C9I78_10470	COG1609	Transcriptional regulator
C9I78_10475	COG3070	regulator of competence-specific genes
C9I78_10495	COG0297	glycogen (starch) synthase activity
C9I78_10500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C9I78_10515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C9I78_10525	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C9I78_10530	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C9I78_10535	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C9I78_10545	COG0542	response to heat
C9I78_10550	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C9I78_10555	COG1278	Cold shock
C9I78_10565	COG1187	pseudouridine synthase activity
C9I78_10570	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C9I78_10580	COG1199	ATP-dependent helicase activity
C9I78_10585	COG0730	response to heat
C9I78_10590	COG3923	Primosomal replication protein n
C9I78_10600	COG0708	Exodeoxyribonuclease III
C9I78_10615	COG4215	(ABC) transporter
C9I78_10645	COG1882	Formate acetyltransferase
C9I78_10655	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9I78_10665	COG3013	Belongs to the UPF0304 family
C9I78_10675	COG2766	serine protein kinase
C9I78_10680	COG2718	Belongs to the UPF0229 family
C9I78_10685	COG2719	SpoVR family
C9I78_10690	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C9I78_10700	COG1663	tetraacyldisaccharide 4'-kinase activity
C9I78_10705	COG1132	(ABC) transporter
C9I78_10710	COG2333	competence protein COMEC
C9I78_10710	COG0658	competence protein
C9I78_10720	COG4591	ABC-type transport system involved in lipoprotein release permease component
C9I78_10725	COG1136	(ABC) transporter
C9I78_10730	COG4591	ABC-type transport system involved in lipoprotein release permease component
C9I78_10740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C9I78_10755	COG1252	NADH dehydrogenase
C9I78_10765	COG3150	esterase
C9I78_10790	COG0537	adenosine 5'-monophosphoramidase activity
C9I78_10820	COG0516	GMP reductase activity
C9I78_10820	COG0517	IMP dehydrogenase activity
C9I78_10830	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
C9I78_10835	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C9I78_10840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9I78_10850	COG2199	diguanylate cyclase activity
C9I78_10865	COG3126	Type III secretion system lipoprotein chaperone (YscW)
C9I78_10870	COG1946	Acyl-CoA thioesterase
C9I78_10880	COG1522	sequence-specific DNA binding
C9I78_10910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_10915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_10960	COG0477	Major facilitator Superfamily
C9I78_10965	COG2855	membrane
C9I78_10980	COG1441	menaquinone biosynthetic process
C9I78_10985	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C9I78_10990	COG0596	Alpha beta hydrolase
C9I78_10995	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C9I78_11000	COG1169	isochorismate synthase
C9I78_11005	COG0436	Aminotransferase
C9I78_11010	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C9I78_11015	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C9I78_11030	COG1555	photosystem II stabilization
C9I78_11035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9I78_11040	COG0776	regulation of translation
C9I78_11045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C9I78_11050	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C9I78_11060	COG0544	peptidyl-prolyl cis-trans isomerase activity
C9I78_11080	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
C9I78_11085	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C9I78_11090	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
C9I78_11095	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C9I78_11115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C9I78_11120	COG0569	domain protein
C9I78_11125	COG0513	Belongs to the DEAD box helicase family
C9I78_11130	COG1253	flavin adenine dinucleotide binding
C9I78_11165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9I78_11170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C9I78_11190	COG1216	Glycosyl transferase, family 2
C9I78_11195	COG2986	histidine ammonia-lyase
C9I78_11220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C9I78_11225	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C9I78_11230	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_11250	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C9I78_11255	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9I78_11260	COG0583	DNA-binding transcription factor activity
C9I78_11265	COG2951	lytic endotransglycosylase activity
C9I78_11270	COG3100	YcgL domain-containing protein
C9I78_11275	COG0850	regulation of cytokinetic process
C9I78_11280	COG2894	cell division
C9I78_11285	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C9I78_11290	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C9I78_11295	COG0318	PFAM AMP-dependent synthetase and ligase
C9I78_11300	COG2267	carboxylic ester hydrolase activity
C9I78_11315	COG1214	PFAM Peptidase M22, glycoprotease
C9I78_11320	COG1199	ATP-dependent helicase activity
C9I78_11325	COG0788	formyltetrahydrofolate deformylase activity
C9I78_11330	COG3102	Protein conserved in bacteria
C9I78_11340	COG0018	arginyl-trna synthetase
C9I78_11360	COG1918	ferrous iron import across plasma membrane
C9I78_11375	COG4977	sequence-specific DNA binding
C9I78_11380	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C9I78_11385	COG1121	(ABC) transporter
C9I78_11390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C9I78_11400	COG0045	succinate-CoA ligase (ADP-forming) activity
C9I78_11405	COG0508	dehydrogenase complex catalyzes the overall conversion of
C9I78_11410	COG0567	Dehydrogenase, E1 component
C9I78_11415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C9I78_11420	COG1053	succinate dehydrogenase
C9I78_11425	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C9I78_11430	COG2009	succinate dehydrogenase
C9I78_11440	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C9I78_11450	COG0033	Phosphoglucomutase
C9I78_11455	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C9I78_11460	COG0596	Alpha beta hydrolase
C9I78_11470	COG0716	FMN binding
C9I78_11480	COG0735	belongs to the Fur family
C9I78_11485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9I78_11490	COG2190	(PTS) system
C9I78_11490	COG1263	PTS System
C9I78_11490	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9I78_11500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C9I78_11505	COG1846	Transcriptional regulator
C9I78_11505	COG1940	carbohydrate kinase activity
C9I78_11510	COG4651	solute:proton antiporter activity
C9I78_11510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C9I78_11515	COG0367	asparagine synthase
C9I78_11520	COG0250	Participates in transcription elongation, termination and antitermination
C9I78_11525	COG3104	oligopeptide transport
C9I78_11530	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C9I78_11535	COG0563	adenylate kinase activity
C9I78_11540	COG0326	Molecular chaperone. Has ATPase activity
C9I78_11545	COG3710	Transcriptional regulator
C9I78_11565	COG0622	Phosphoesterase
C9I78_11595	COG1090	epimerase
C9I78_11600	COG0300	oxidoreductase activity
C9I78_11610	COG3118	belongs to the thioredoxin family
C9I78_11615	COG0330	HflC and HflK could
C9I78_11645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C9I78_11650	COG3115	cell septum assembly
C9I78_11655	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
C9I78_11660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C9I78_11670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_11675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9I78_11680	COG2190	(PTS) system
C9I78_11690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_11695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_11705	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_11715	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_11725	COG3951	Flagellar rod assembly protein muramidase FlgJ
C9I78_11725	COG1705	Flagellar rod assembly protein muramidase FlgJ
C9I78_11730	COG1706	bacterial-type flagellum-dependent cell motility
C9I78_11735	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C9I78_11740	COG4786	Flagellar basal body rod
C9I78_11745	COG4787	bacterial-type flagellum-dependent cell motility
C9I78_11755	COG1749	Flagellar hook protein flgE
C9I78_11760	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C9I78_11765	COG1558	bacterial-type flagellum-dependent cell motility
C9I78_11770	COG1815	bacterial-type flagellum-dependent cell motility
C9I78_11775	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C9I78_11780	COG0835	chemotaxis
C9I78_11780	COG0784	Response regulator, receiver
C9I78_11840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C9I78_11845	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C9I78_11860	COG2217	Heavy metal translocating P-type atpase
C9I78_11860	COG2608	mercury ion transmembrane transporter activity
C9I78_11900	COG2840	Smr protein MutS2
C9I78_11905	COG1187	pseudouridine synthase activity
C9I78_11915	COG0737	Belongs to the 5'-nucleotidase family
C9I78_11920	COG2877	3-deoxy-8-phosphooctulonate synthase activity
C9I78_11925	COG2912	Transglutaminase-like superfamily
C9I78_11930	COG3094	Invasion gene expression up-regulator, SirB
C9I78_11935	COG2890	protein-(glutamine-N5) methyltransferase activity
C9I78_11940	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C9I78_11945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C9I78_11950	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C9I78_11955	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C9I78_11960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C9I78_11965	COG0193	aminoacyl-tRNA hydrolase activity
C9I78_11970	COG0012	GTP binding
C9I78_12085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C9I78_12095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C9I78_12100	COG1702	phosphate starvation-inducible protein PhoH
C9I78_12105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C9I78_12110	COG4535	Mg2 and Co2 transporter CorC
C9I78_12115	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C9I78_12120	COG2888	peptidyl-tyrosine sulfation
C9I78_12125	COG0495	leucyl-tRNA aminoacylation
C9I78_12130	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
C9I78_12135	COG1466	dna polymerase III delta subunit
C9I78_12140	COG0799	negative regulation of ribosome biogenesis
C9I78_12145	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C9I78_12150	COG0768	penicillin binding
C9I78_12155	COG0772	Belongs to the SEDS family
C9I78_12160	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C9I78_12165	COG1686	Belongs to the peptidase S11 family
C9I78_12170	COG2921	Belongs to the UPF0250 family
C9I78_12175	COG0321	lipoyl(octanoyl) transferase activity
C9I78_12180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C9I78_12185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C9I78_12190	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C9I78_12205	COG0366	Alpha amylase catalytic
C9I78_12210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9I78_12210	COG1263	PTS System
C9I78_12220	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C9I78_12230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C9I78_12235	COG2011	ABC-type metal ion transport system permease component
C9I78_12240	COG1464	Belongs to the NlpA lipoprotein family
C9I78_12245	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
C9I78_12255	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C9I78_12255	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C9I78_12265	COG3706	GGDEF domain
C9I78_12265	COG0745	RESPONSE REGULATOR receiver
C9I78_12270	COG1611	Belongs to the LOG family
C9I78_12275	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9I78_12285	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
C9I78_12290	COG2363	Small membrane protein
C9I78_12300	COG0583	DNA-binding transcription factor activity
C9I78_12305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9I78_12305	COG0301	tRNA thio-modification
C9I78_12310	COG2885	chlorophyll binding
C9I78_12315	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C9I78_12320	COG1722	exodeoxyribonuclease VII activity
C9I78_12325	COG0142	geranyltranstransferase activity
C9I78_12330	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C9I78_12335	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C9I78_12340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C9I78_12345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C9I78_12365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I78_12365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I78_12370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C9I78_12375	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C9I78_12380	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C9I78_12395	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C9I78_12400	COG2252	PERMEase
C9I78_12405	COG2195	Cleaves the N-terminal amino acid of tripeptides
C9I78_12430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C9I78_12430	COG0047	phosphoribosylformylglycinamidine synthase activity
C9I78_12435	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C9I78_12445	COG0590	tRNA wobble adenosine to inosine editing
C9I78_12450	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C9I78_12490	COG0484	heat shock protein binding
C9I78_12495	COG0443	Heat shock 70 kDa protein
C9I78_12505	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C9I78_12510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C9I78_12520	COG0497	DNA recombination
C9I78_12525	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9I78_12530	COG2914	Belongs to the UPF0125 (RnfH) family
C9I78_12535	COG2867	negative regulation of translational initiation
C9I78_12540	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C9I78_12550	COG0582	viral genome integration into host DNA
C9I78_12610	COG0732	type I restriction modification DNA specificity domain
C9I78_12650	COG3706	GGDEF domain
C9I78_12650	COG0745	RESPONSE REGULATOR receiver
C9I78_12700	COG0583	DNA-binding transcription factor activity
C9I78_12705	COG3153	acetyltransferase
C9I78_12705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C9I78_12725	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C9I78_12730	COG2873	o-acetylhomoserine
C9I78_12765	COG1115	amino acid carrier protein
C9I78_12775	COG1584	GPR1 FUN34 yaaH family protein
C9I78_12785	COG1757	Na H antiporter
C9I78_12865	COG0582	viral genome integration into host DNA
C9I78_12870	COG0519	Catalyzes the synthesis of GMP from XMP
C9I78_12870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C9I78_12875	COG0517	IMP dehydrogenase activity
C9I78_12875	COG0516	GMP reductase activity
C9I78_12880	COG1570	exodeoxyribonuclease VII activity
C9I78_12895	COG1160	GTP binding
C9I78_12900	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9I78_12905	COG2976	Protein conserved in bacteria
C9I78_12910	COG0124	histidyl-tRNA synthetase
C9I78_12915	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C9I78_12930	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C9I78_12935	COG0105	UTP biosynthetic process
C9I78_12940	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C9I78_12945	COG2975	iron-sulfur cluster assembly
C9I78_12950	COG0633	Ferredoxin
C9I78_12955	COG0443	Heat shock 70 kDa protein
C9I78_12960	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C9I78_12970	COG0822	iron-sulfur transferase activity
C9I78_12975	COG1104	cysteine desulfurase activity
C9I78_12980	COG1959	2 iron, 2 sulfur cluster binding
C9I78_12990	COG0483	inositol monophosphate 1-phosphatase activity
C9I78_13000	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9I78_13005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9I78_13010	COG1862	Preprotein translocase
C9I78_13015	COG0343	queuine tRNA-ribosyltransferase activity
C9I78_13020	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C9I78_13035	COG0517	IMP dehydrogenase activity
C9I78_13045	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C9I78_13055	COG0583	DNA-binding transcription factor activity
C9I78_13060	COG0450	alkyl hydroperoxide reductase
C9I78_13070	COG3142	Participates in the control of copper homeostasis
C9I78_13080	COG0704	Plays a role in the regulation of phosphate uptake
C9I78_13085	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C9I78_13090	COG0581	inorganic phosphate transmembrane transporter activity
C9I78_13100	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C9I78_13105	COG0248	Ppx GppA phosphatase
C9I78_13115	COG5002	protein histidine kinase activity
C9I78_13120	COG0745	RESPONSE REGULATOR receiver
C9I78_13130	COG2974	May be involved in recombination
C9I78_13140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9I78_13200	COG0542	response to heat
C9I78_13210	COG0564	pseudouridine synthase activity
C9I78_13215	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9I78_13220	COG0741	lytic transglycosylase activity
C9I78_13225	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C9I78_13230	COG1605	Chorismate mutase
C9I78_13230	COG0077	Prephenate dehydratase
C9I78_13235	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
C9I78_13240	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
C9I78_13250	COG0488	(ABC) transporter
C9I78_13265	COG0739	heme binding
C9I78_13270	COG1605	Chorismate mutase
C9I78_13270	COG0287	Prephenate dehydrogenase
C9I78_13275	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9I78_13280	COG1472	Belongs to the glycosyl hydrolase 3 family
C9I78_13285	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C9I78_13290	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C9I78_13305	COG1966	Carbon starvation protein
C9I78_13310	COG3275	phosphorelay sensor kinase activity
C9I78_13315	COG3279	Response regulator of the LytR AlgR family
C9I78_13320	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C9I78_13325	COG1047	Peptidyl-prolyl cis-trans
C9I78_13330	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C9I78_13335	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C9I78_13340	COG0196	riboflavin kinase activity
C9I78_13345	COG0728	peptidoglycan biosynthetic process
C9I78_13350	COG0268	Binds directly to 16S ribosomal RNA
C9I78_13360	COG0640	Transcriptional regulator
C9I78_13370	COG0583	DNA-binding transcription factor activity
C9I78_13375	COG1283	sodium-dependent phosphate transmembrane transporter activity
C9I78_13385	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C9I78_13390	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C9I78_13395	COG0730	response to heat
C9I78_13405	COG0494	nUDIX hydrolase
C9I78_13415	COG3066	DNA modification
C9I78_13425	COG0667	Aldo Keto reductase
C9I78_13440	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C9I78_13450	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C9I78_13455	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9I78_13465	COG0716	FMN binding
C9I78_13475	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C9I78_13480	COG0513	Belongs to the DEAD box helicase family
C9I78_13485	COG3022	response to hydroperoxide
C9I78_13490	COG1115	amino acid carrier protein
C9I78_13505	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C9I78_13515	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C9I78_13520	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
C9I78_13525	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
C9I78_13575	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C9I78_13580	COG0083	homoserine kinase activity
C9I78_13595	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C9I78_13610	COG0745	RESPONSE REGULATOR receiver
C9I78_13620	COG0784	Response regulator, receiver
C9I78_13620	COG5002	protein histidine kinase activity
C9I78_13620	COG2198	Histidine kinase
C9I78_13625	COG4251	negative regulation of phosphorylation
C9I78_13625	COG5001	Diguanylate cyclase
C9I78_13625	COG3706	GGDEF domain
C9I78_13625	COG2203	Gaf domain
C9I78_13630	COG1242	4 iron, 4 sulfur cluster binding
C9I78_13635	COG0069	glutamate synthase activity
C9I78_13635	COG0070	glutamate synthase
C9I78_13635	COG0067	glutamate synthase
C9I78_13645	COG0067	glutamate synthase
C9I78_13645	COG0069	glutamate synthase activity
C9I78_13645	COG0070	glutamate synthase
C9I78_13650	COG0493	'glutamate synthase
C9I78_13660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C9I78_13670	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9I78_13675	COG2860	membrane
C9I78_13680	COG0583	DNA-binding transcription factor activity
C9I78_13685	COG0730	response to heat
C9I78_13700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C9I78_13705	COG0505	Belongs to the CarA family
C9I78_13710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C9I78_13715	COG0494	nUDIX hydrolase
C9I78_13720	COG0653	protein targeting
C9I78_13730	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C9I78_13735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C9I78_13740	COG0849	cell division
C9I78_13745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C9I78_13750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C9I78_13755	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C9I78_13760	COG0772	Belongs to the SEDS family
C9I78_13765	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C9I78_13770	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C9I78_13775	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C9I78_13780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C9I78_13785	COG0768	penicillin binding
C9I78_13790	COG3116	cell division
C9I78_13795	COG0275	rRNA processing
C9I78_13810	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C9I78_13820	COG0792	nuclease activity
C9I78_13825	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C9I78_13830	COG2823	Periplasmic or secreted lipoprotein
C9I78_13835	COG2969	positive regulation of protein catabolic process
C9I78_13840	COG0625	glutathione transferase activity
C9I78_13845	COG2857	Cytochrome c1
C9I78_13850	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C9I78_13855	COG0723	plastoquinol--plastocyanin reductase activity
C9I78_13860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C9I78_13865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C9I78_13875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C9I78_13885	COG3105	Protein conserved in bacteria
C9I78_13895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C9I78_13905	COG0187	DNA topoisomerase II activity
C9I78_13910	COG3150	esterase
C9I78_13920	COG3151	Protein conserved in bacteria
C9I78_13925	COG0494	nUDIX hydrolase
C9I78_13930	COG1538	Outer membrane efflux protein
C9I78_13935	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C9I78_13935	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C9I78_13940	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C9I78_13955	COG3025	triphosphatase activity
C9I78_13960	COG1392	Phosphate transport regulator
C9I78_13965	COG0306	phosphate transporter
C9I78_13970	COG4991	sh3 domain protein
C9I78_13980	COG3409	Peptidoglycan-binding domain 1 protein
C9I78_13980	COG3267	Type II secretory pathway component ExeA
C9I78_13985	COG0617	tRNA 3'-terminal CCA addition
C9I78_13990	COG1968	undecaprenyl-diphosphatase activity
C9I78_13995	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C9I78_14000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C9I78_14005	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C9I78_14010	COG0596	Alpha beta hydrolase
C9I78_14015	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C9I78_14020	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C9I78_14025	COG1610	YqeY-like protein
C9I78_14030	COG0358	DNA primase activity
C9I78_14035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C9I78_14080	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_14090	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_14105	COG3550	peptidyl-serine autophosphorylation
C9I78_14115	COG5001	Diguanylate cyclase
C9I78_14115	COG3300	MHYT domain
C9I78_14165	COG0732	type I restriction modification DNA specificity domain
C9I78_14190	COG2264	protein methyltransferase activity
C9I78_14200	COG1162	GTPase activity
C9I78_14210	COG3706	GGDEF domain
C9I78_14245	COG1464	Belongs to the NlpA lipoprotein family
C9I78_14255	COG2207	Transcriptional regulator
C9I78_14290	COG2213	PTS system mannitol-specific
C9I78_14290	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_14295	COG0246	Mannitol dehydrogenase
C9I78_14300	COG3722	fumarate hydratase activity
C9I78_14315	COG1461	Dihydroxyacetone kinase
C9I78_14320	COG2376	Dihydroxyacetone kinase
C9I78_14330	COG5002	protein histidine kinase activity
C9I78_14345	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C9I78_14350	COG1349	DNA-binding transcription factor activity
C9I78_14360	COG0469	pyruvate kinase activity
C9I78_14370	COG3706	GGDEF domain
C9I78_14375	COG0440	acetolactate synthase activity
C9I78_14380	COG0028	Belongs to the TPP enzyme family
C9I78_14385	COG1022	Amp-dependent synthetase and ligase
C9I78_14390	COG0583	DNA-binding transcription factor activity
C9I78_14410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C9I78_14415	COG0473	3-isopropylmalate dehydrogenase activity
C9I78_14420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C9I78_14425	COG0066	3-isopropylmalate dehydratase activity
C9I78_14435	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C9I78_14440	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C9I78_14445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9I78_14450	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C9I78_14455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C9I78_14460	COG2967	ApaG domain
C9I78_14465	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C9I78_14480	COG2966	Psort location CytoplasmicMembrane, score
C9I78_14485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C9I78_14495	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C9I78_14500	COG0142	geranyltranstransferase activity
C9I78_14510	COG0039	L-malate dehydrogenase activity
C9I78_14545	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C9I78_14550	COG1178	ABC-type Fe3 transport system permease component
C9I78_14555	COG4143	(ABC) transporter
C9I78_14560	COG0163	prenyltransferase activity
C9I78_14565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C9I78_14575	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C9I78_14580	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C9I78_14590	COG2105	PFAM AIG2 family protein
C9I78_14595	COG2911	Protein conserved in bacteria
C9I78_14600	COG0729	surface antigen
C9I78_14605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_14615	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C9I78_14630	COG4181	ATPase activity
C9I78_14650	COG0529	Catalyzes the synthesis of activated sulfate
C9I78_14655	COG3273	potassium ion transport
C9I78_14655	COG0471	metal ion transport
C9I78_14665	COG2895	sulfate adenylyltransferase (ATP) activity
C9I78_14670	COG0175	sulfate reduction
C9I78_14675	COG1648	precorrin-2 dehydrogenase activity
C9I78_14675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C9I78_14680	COG0737	Belongs to the 5'-nucleotidase family
C9I78_14690	COG0513	Belongs to the DEAD box helicase family
C9I78_14695	COG2153	protein acetylation
C9I78_14705	COG0545	Peptidyl-prolyl cis-trans isomerase
C9I78_14715	COG0203	ribosomal protein L17
C9I78_14720	COG0202	RNA polymerase activity
C9I78_14730	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C9I78_14735	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C9I78_14745	COG0201	protein transport
C9I78_14750	COG0200	Binds to the 23S rRNA
C9I78_14755	COG1841	ribosomal large subunit assembly
C9I78_14770	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C9I78_14775	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C9I78_14780	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C9I78_14785	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C9I78_14790	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C9I78_14795	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C9I78_14800	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C9I78_14805	COG0255	Belongs to the universal ribosomal protein uL29 family
C9I78_14815	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C9I78_14820	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C9I78_14825	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C9I78_14830	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C9I78_14840	COG0088	Forms part of the polypeptide exit tunnel
C9I78_14845	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C9I78_14855	COG0254	rRNA binding
C9I78_14865	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C9I78_14870	COG1609	Transcriptional regulator
C9I78_14880	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C9I78_14885	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C9I78_14890	COG1575	Belongs to the MenA family. Type 1 subfamily
C9I78_14895	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C9I78_14900	COG3074	FtsZ-dependent cytokinesis
C9I78_14910	COG1494	fructose-1,6-bisphosphatase
C9I78_14935	COG0149	triose-phosphate isomerase activity
C9I78_14940	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
C9I78_14955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C9I78_14960	COG1215	transferase activity, transferring glycosyl groups
C9I78_14970	COG0438	transferase activity, transferring glycosyl groups
C9I78_14975	COG0463	Glycosyl transferase, family 2
C9I78_14975	COG1216	Glycosyl transferase, family 2
C9I78_14995	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
C9I78_15025	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C9I78_15035	COG1560	Kdo2-lipid A biosynthetic process
C9I78_15045	COG0859	PFAM glycosyl transferase family 9
C9I78_15050	COG1519	Transferase
C9I78_15065	COG0367	asparagine synthase
C9I78_15080	COG0728	peptidoglycan biosynthetic process
C9I78_15090	COG1083	cytidylyl-transferase
C9I78_15095	COG3642	lipopolysaccharide core region biosynthetic process
C9I78_15100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C9I78_15105	COG0859	PFAM glycosyl transferase family 9
C9I78_15110	COG0463	Glycosyl transferase, family 2
C9I78_15125	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C9I78_15130	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C9I78_15140	COG2194	sulfuric ester hydrolase activity
C9I78_15150	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C9I78_15155	COG2003	Belongs to the UPF0758 family
C9I78_15170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C9I78_15175	COG1309	transcriptional regulator
C9I78_15180	COG1560	Kdo2-lipid A biosynthetic process
C9I78_15185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C9I78_15190	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C9I78_15200	COG1561	YicC-like family, N-terminal region
C9I78_15275	COG1061	Type III restriction enzyme res subunit
C9I78_15335	COG4608	Belongs to the ABC transporter superfamily
C9I78_15340	COG0444	Belongs to the ABC transporter superfamily
C9I78_15345	COG0747	negative chemotaxis
C9I78_15355	COG4174	ABC transporter (Permease)
C9I78_15380	COG0811	peptide transport
C9I78_15385	COG0848	biopolymer transport protein
C9I78_15400	COG0194	GDP metabolic process
C9I78_15405	COG1758	RNA polymerase activity
C9I78_15410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C9I78_15415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C9I78_15420	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C9I78_15430	COG2233	PERMEase
C9I78_15435	COG2205	protein histidine kinase activity
C9I78_15440	COG0745	RESPONSE REGULATOR receiver
C9I78_15450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9I78_15460	COG2183	response to ionizing radiation
C9I78_15470	COG0596	Alpha beta hydrolase
C9I78_15475	COG1040	competence protein
C9I78_15480	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C9I78_15480	COG0316	Belongs to the HesB IscA family
C9I78_15485	COG0494	nUDIX hydrolase
C9I78_15490	COG1218	3'(2'),5'-bisphosphate nucleotidase
C9I78_15500	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C9I78_15505	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C9I78_15510	COG3156	type II secretion system protein K
C9I78_15515	COG4795	General secretion pathway protein
C9I78_15520	COG2165	general secretion pathway protein
C9I78_15525	COG2165	general secretion pathway protein
C9I78_15530	COG2165	general secretion pathway protein
C9I78_15535	COG1459	type II secretion system
C9I78_15540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C9I78_15550	COG3031	protein transport across the cell outer membrane
C9I78_15555	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C9I78_15560	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C9I78_15565	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C9I78_15575	COG0456	acetyltransferase
C9I78_15580	COG1490	D-aminoacyl-tRNA deacylase activity
C9I78_15585	COG1295	ribonuclease BN
C9I78_15605	COG0174	glutamine synthetase
C9I78_15615	COG3852	Histidine kinase
C9I78_15620	COG2204	response regulator
C9I78_15630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C9I78_15635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C9I78_15670	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C9I78_15680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9I78_15680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C9I78_15705	COG0084	hydrolase, TatD family'
C9I78_15715	COG0805	protein transport
C9I78_15725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C9I78_15730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C9I78_15735	COG3165	ubiquinone biosynthetic process from chorismate
C9I78_15740	COG2226	methyltransferase
C9I78_15745	COG1322	Protein conserved in bacteria
C9I78_15760	COG0628	permease
C9I78_15790	COG1597	lipid kinase activity
C9I78_15810	COG2823	Periplasmic or secreted lipoprotein
C9I78_15820	COG2081	HI0933 family
C9I78_15830	COG1528	Iron-storage protein
C9I78_15835	COG0589	response to stress
C9I78_15840	COG0697	spore germination
C9I78_15850	COG0742	ribosomal rna small subunit methyltransferase
C9I78_15855	COG5002	protein histidine kinase activity
C9I78_15855	COG5001	Diguanylate cyclase
C9I78_15860	COG1522	sequence-specific DNA binding
C9I78_15865	COG0339	signal peptide processing
C9I78_15875	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C9I78_15880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9I78_15885	COG0583	DNA-binding transcription factor activity
C9I78_15890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C9I78_15895	COG0800	Aldolase
C9I78_15900	COG2610	gluconate transmembrane transporter activity
C9I78_15905	COG3265	gluconokinase activity
C9I78_15910	COG0129	dihydroxy-acid dehydratase activity
C9I78_15915	COG2076	Multidrug Resistance protein
C9I78_15925	COG0583	DNA-binding transcription factor activity
C9I78_15930	COG1609	Transcriptional regulator
C9I78_15970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C9I78_15980	COG0747	negative chemotaxis
C9I78_15985	COG4172	Belongs to the ABC transporter superfamily
C9I78_16050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_16055	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_16065	COG2960	long-chain fatty acid transporting porin activity
C9I78_16070	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C9I78_16075	COG0583	DNA-binding transcription factor activity
C9I78_16125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C9I78_16130	COG1739	Uncharacterized protein family UPF0029
C9I78_16135	COG1024	Enoyl-CoA hydratase
C9I78_16135	COG1250	3-hydroxyacyl-CoA dehydrogenase
C9I78_16140	COG0183	Belongs to the thiolase family
C9I78_16145	COG0604	alcohol dehydrogenase
C9I78_16160	COG0425	Belongs to the sulfur carrier protein TusA family
C9I78_16170	COG2119	membrane
C9I78_16175	COG0752	glycyl-tRNA synthetase alpha subunit
C9I78_16180	COG0751	glycine-tRNA ligase activity
C9I78_16185	COG0366	Alpha amylase catalytic
C9I78_16190	COG3977	Valine--pyruvate aminotransferase
C9I78_16195	COG0071	Belongs to the small heat shock protein (HSP20) family
C9I78_16215	COG0187	DNA topoisomerase II activity
C9I78_16220	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C9I78_16225	COG0592	DNA-directed DNA polymerase activity
C9I78_16230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C9I78_16250	COG1126	abc transporter atp-binding protein
C9I78_16260	COG0594	ribonuclease P activity
C9I78_16265	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C9I78_16270	COG0706	membrane insertase activity
C9I78_16275	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C9I78_16280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C9I78_16285	COG0445	tRNA wobble uridine modification
C9I78_16290	COG0357	Ribosomal RNA small subunit methyltransferase G
C9I78_16295	COG1192	Involved in chromosome partitioning
C9I78_16300	COG1475	DNA binding
C9I78_16305	COG3312	ion transport
C9I78_16310	COG0356	it plays a direct role in the translocation of protons across the membrane
C9I78_16325	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C9I78_16330	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C9I78_16335	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C9I78_16340	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C9I78_16345	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C9I78_16350	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C9I78_16355	COG0765	amino acid transport
C9I78_16360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_16365	COG2814	Major facilitator Superfamily
C9I78_16370	COG0583	DNA-binding transcription factor activity
C9I78_16380	COG0129	dihydroxy-acid dehydratase activity
C9I78_16385	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C9I78_16390	COG3978	acetolactate synthase activity
C9I78_16400	COG0606	chelatase, subunit chli
C9I78_16410	COG0204	Acyl-transferase
C9I78_16415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9I78_16420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C9I78_16430	COG3084	Protein conserved in bacteria
C9I78_16440	COG4326	sporulation control protein
C9I78_16445	COG1272	protein, Hemolysin III
C9I78_16455	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C9I78_16460	COG0569	domain protein
C9I78_16465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C9I78_16465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C9I78_16470	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C9I78_16475	COG0242	peptide deformylase activity
C9I78_16485	COG0758	DNA mediated transformation
C9I78_16490	COG2922	Belongs to the Smg family
C9I78_16495	COG0551	DNA topoisomerase type I activity
C9I78_16500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C9I78_16505	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C9I78_16510	COG0009	L-threonylcarbamoyladenylate synthase
C9I78_16515	COG0408	coproporphyrinogen oxidase activity
C9I78_16520	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C9I78_16530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C9I78_16595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C9I78_16600	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C9I78_16605	COG0352	thiamine-phosphate diphosphorylase activity
C9I78_16610	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9I78_16615	COG2104	thiamine diphosphate biosynthetic process
C9I78_16620	COG2022	thiamine diphosphate biosynthetic process
C9I78_16630	COG0006	proline dipeptidase activity
C9I78_16630	COG0006	proline dipeptidase activity
C9I78_16660	COG3220	belongs to the UPF0276 family
C9I78_16670	COG0210	DNA helicase
C9I78_16680	COG0405	Gamma-glutamyltransferase
C9I78_16685	COG1280	lysine exporter protein (LysE YggA)
C9I78_16695	COG2962	Rard protein
C9I78_16700	COG0514	ATP-dependent DNA helicase (RecQ)
C9I78_16715	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C9I78_16720	COG0248	Ppx GppA phosphatase
C9I78_16725	COG0513	Belongs to the DEAD box helicase family
C9I78_16730	COG3118	belongs to the thioredoxin family
C9I78_16735	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
C9I78_16750	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C9I78_16755	COG0633	Ferredoxin
C9I78_16810	COG3071	HemY protein
C9I78_16815	COG2959	enzyme of heme biosynthesis
C9I78_16820	COG1587	Uroporphyrinogen-III synthase
C9I78_16825	COG0181	hydroxymethylbilane synthase activity
C9I78_16830	COG3072	Adenylate cyclase
C9I78_16835	COG1965	Belongs to the frataxin family
C9I78_16845	COG0019	diaminopimelate decarboxylase activity
C9I78_16850	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C9I78_16860	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C9I78_16865	COG1011	Hydrolase
C9I78_16870	COG3287	FIST C domain
C9I78_16870	COG2199	diguanylate cyclase activity
C9I78_16870	COG2200	EAL domain
C9I78_16890	COG0561	phosphatase activity
C9I78_16900	COG2267	carboxylic ester hydrolase activity
C9I78_16905	COG1280	lysine exporter protein (LysE YggA)
C9I78_16910	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C9I78_16915	COG0640	Transcriptional regulator
C9I78_16920	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C9I78_16980	COG2095	MarC family integral membrane protein
C9I78_16985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C9I78_17000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9I78_17035	COG0742	ribosomal rna small subunit methyltransferase
C9I78_17040	COG0552	protein localization to endoplasmic reticulum
C9I78_17045	COG2884	Cell division ATP-binding protein ftsE
C9I78_17050	COG2177	Part of the ABC transporter FtsEX involved in
C9I78_17065	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9I78_17070	COG0705	Rhomboid family
C9I78_17075	COG1580	Controls the rotational direction of flagella during chemotaxis
C9I78_17080	COG3161	chorismate lyase activity
C9I78_17085	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C9I78_17090	COG2937	Belongs to the GPAT DAPAT family
C9I78_17105	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C9I78_17110	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C9I78_17115	COG0534	Mate efflux family protein
C9I78_17120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C9I78_17135	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C9I78_17140	COG4206	TonB-dependent receptor
C9I78_17150	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C9I78_17220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9I78_17230	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C9I78_17285	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9I78_17360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C9I78_17365	COG5001	Diguanylate cyclase
C9I78_17370	COG1869	D-ribose catabolic process
C9I78_17375	COG1129	ABC transporter
C9I78_17380	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9I78_17385	COG1879	ABC-type sugar transport system periplasmic component
C9I78_17390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I78_17395	COG1609	Transcriptional regulator
C9I78_17410	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C9I78_17430	COG0745	RESPONSE REGULATOR receiver
C9I78_17445	COG1785	Belongs to the alkaline phosphatase family
C9I78_17465	COG3706	GGDEF domain
C9I78_17465	COG0745	RESPONSE REGULATOR receiver
C9I78_17475	COG0814	amino acid
C9I78_17480	COG0456	acetyltransferase
C9I78_17485	COG0243	molybdopterin cofactor binding
C9I78_17490	COG1648	precorrin-2 dehydrogenase activity
C9I78_17490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C9I78_17510	COG3707	response regulator
C9I78_17520	COG1116	anion transmembrane transporter activity
C9I78_17520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9I78_17525	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I78_17530	COG1116	anion transmembrane transporter activity
C9I78_17535	COG2146	nitrite reductase [NAD(P)H] activity
C9I78_17535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9I78_17590	COG0515	serine threonine protein kinase
C9I78_17590	COG2815	serine threonine protein kinase
C9I78_17630	COG0631	protein serine/threonine phosphatase activity
C9I78_17685	COG3501	Rhs element vgr protein
C9I78_17700	COG0420	3'-5' exonuclease activity
C9I78_17705	COG0419	ATPase involved in DNA repair
C9I78_17725	COG3040	lipid binding
C9I78_17735	COG2814	Major facilitator Superfamily
C9I78_17745	COG1288	antiporter activity
C9I78_17760	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C9I78_17775	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C9I78_17795	COG0583	DNA-binding transcription factor activity
C9I78_17800	COG0277	FAD linked oxidase domain protein
C9I78_17820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C9I78_17860	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C9I78_17860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9I78_17910	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C9I78_17915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C9I78_17920	COG2146	nitrite reductase [NAD(P)H] activity
C9I78_17925	COG2116	formate transmembrane transporter activity
C9I78_17945	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C9I78_17980	COG0534	Mate efflux family protein
C9I78_17990	COG2814	Major facilitator Superfamily
C9I78_17995	COG3118	belongs to the thioredoxin family
C9I78_18000	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C9I78_18025	COG2271	Major facilitator Superfamily
C9I78_18030	COG3851	Histidine kinase
C9I78_18035	COG2197	response regulator
C9I78_18045	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C9I78_18050	COG0583	DNA-binding transcription factor activity
C9I78_18060	COG0243	molybdopterin cofactor binding
C9I78_18065	COG0446	pyridine nucleotide-disulphide oxidoreductase
C9I78_18110	COG3706	GGDEF domain
C9I78_18160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C9I78_18165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C9I78_18205	COG4735	regulation of single-species biofilm formation
C9I78_18295	COG3550	peptidyl-serine autophosphorylation
C9I78_18330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_18350	COG1328	CTP reductase activity
C9I78_18355	COG0602	queuosine metabolic process
C9I78_18360	COG0534	Mate efflux family protein
C9I78_18380	COG4067	protein conserved in archaea
C9I78_18380	COG0189	ligase activity
C9I78_18390	COG3111	PFAM Bacterial OB fold (BOF) protein
C9I78_18395	COG1492	cobalamin metabolic process
C9I78_18400	COG0725	ABC transporter, periplasmic molybdate-binding protein
C9I78_18405	COG4149	molybdate abc transporter
C9I78_18410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C9I78_18420	COG3706	GGDEF domain
C9I78_18420	COG4251	negative regulation of phosphorylation
C9I78_18420	COG2203	Gaf domain
C9I78_18420	COG5001	Diguanylate cyclase
C9I78_18430	COG0745	RESPONSE REGULATOR receiver
C9I78_18430	COG3706	GGDEF domain
C9I78_18445	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C9I78_18450	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C9I78_18475	COG3140	Belongs to the UPF0181 family
C9I78_18480	COG0589	response to stress
C9I78_18490	COG0583	DNA-binding transcription factor activity
C9I78_18505	COG0023	Translation Initiation Factor
C9I78_18515	COG1181	Belongs to the D-alanine--D-alanine ligase family
C9I78_18525	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9I78_18525	COG1042	CoA-binding domain protein
C9I78_18525	COG0045	succinate-CoA ligase (ADP-forming) activity
C9I78_18530	COG0583	DNA-binding transcription factor activity
C9I78_18545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C9I78_18550	COG3447	MASE1 domain protein
C9I78_18550	COG5001	Diguanylate cyclase
C9I78_18550	COG5002	protein histidine kinase activity
C9I78_18555	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
C9I78_18560	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
C9I78_18565	COG1984	allophanate hydrolase subunit 2
C9I78_18575	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C9I78_18580	COG4181	ATPase activity
C9I78_18590	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C9I78_18595	COG3300	MHYT domain
C9I78_18595	COG5001	Diguanylate cyclase
C9I78_18605	COG0484	heat shock protein binding
C9I78_18630	COG4533	DNA binding
C9I78_18640	COG2050	protein possibly involved in aromatic compounds catabolism
C9I78_18655	COG2067	long-chain fatty acid transport protein
C9I78_18660	COG2267	carboxylic ester hydrolase activity
C9I78_18675	COG0861	Integral membrane protein TerC family
C9I78_18680	COG0737	Belongs to the 5'-nucleotidase family
C9I78_18685	COG3593	DNA synthesis involved in DNA repair
C9I78_18695	COG0583	DNA-binding transcription factor activity
C9I78_18700	COG2116	formate transmembrane transporter activity
C9I78_18705	COG2353	YceI-like domain
C9I78_18710	COG3038	cytochrome b561
C9I78_18725	COG4943	cyclic-guanylate-specific phosphodiesterase activity
C9I78_18730	COG0513	Belongs to the DEAD box helicase family
C9I78_18735	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
C9I78_18745	COG0840	transmembrane signaling receptor activity
C9I78_18755	COG0546	phosphoglycolate phosphatase activity
C9I78_18765	COG0784	Response regulator, receiver
C9I78_18765	COG3437	response regulator, receiver
C9I78_18785	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I78_18790	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C9I78_18795	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C9I78_18810	COG2207	Transcriptional regulator
C9I78_18815	COG1979	alcohol dehydrogenase
C9I78_18835	COG1840	ABC-type Fe3 transport system, periplasmic component
C9I78_18840	COG2271	Major facilitator Superfamily
C9I78_18845	COG0469	pyruvate kinase activity
C9I78_18850	COG1126	abc transporter atp-binding protein
C9I78_18855	COG0765	amino acid transport
C9I78_18860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_18865	COG0765	amino acid transport
C9I78_18870	COG2203	Gaf domain
C9I78_18870	COG2199	diguanylate cyclase activity
C9I78_18870	COG2200	EAL domain
C9I78_18890	COG1609	Transcriptional regulator
C9I78_18895	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_18895	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_18900	COG1105	Belongs to the carbohydrate kinase PfkB family
C9I78_18905	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C9I78_18905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_18905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_18945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C9I78_18950	COG0509	glycine decarboxylation via glycine cleavage system
C9I78_18955	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C9I78_18955	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C9I78_18995	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
C9I78_19000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C9I78_19005	COG0583	DNA-binding transcription factor activity
C9I78_19010	COG2176	DNA-directed DNA polymerase activity
C9I78_19055	COG0242	peptide deformylase activity
C9I78_19085	COG2239	Acts as a magnesium transporter
C9I78_19105	COG0346	lactoylglutathione lyase activity
C9I78_19110	COG1902	pentaerythritol trinitrate reductase activity
C9I78_19135	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C9I78_19145	COG0069	glutamate synthase activity
C9I78_19145	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C9I78_19155	COG4565	transcriptional regulatory protein
C9I78_19160	COG3290	protein histidine kinase activity
C9I78_19165	COG0471	metal ion transport
C9I78_19195	COG2076	Multidrug Resistance protein
C9I78_19210	COG0671	phosphoesterase, PA-phosphatase related
C9I78_19225	COG2962	Rard protein
C9I78_19245	COG0835	chemotaxis
C9I78_19245	COG0784	Response regulator, receiver
C9I78_19270	COG2197	response regulator
C9I78_19280	COG3706	GGDEF domain
C9I78_19285	COG2197	response regulator
C9I78_19290	COG5001	Diguanylate cyclase
C9I78_19290	COG3300	MHYT domain
C9I78_19365	COG4964	Belongs to the GSP D family
C9I78_19390	COG2207	Transcriptional regulator
C9I78_19410	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C9I78_19440	COG3069	C4-dicarboxylate transmembrane transporter activity
C9I78_19445	COG1704	LemA family
C9I78_19450	COG0501	Belongs to the peptidase M48B family
C9I78_19480	COG0641	radical SAM
C9I78_19500	COG3111	PFAM Bacterial OB fold (BOF) protein
C9I78_19505	COG1597	lipid kinase activity
C9I78_19510	COG0583	DNA-binding transcription factor activity
C9I78_19515	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I78_19515	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C9I78_19545	COG0714	Associated with various cellular activities
C9I78_19550	COG0641	radical SAM
C9I78_19555	COG3119	arylsulfatase activity
C9I78_19570	COG3119	arylsulfatase activity
C9I78_19575	COG3119	arylsulfatase activity
C9I78_19580	COG0745	RESPONSE REGULATOR receiver
C9I78_19595	COG2205	protein histidine kinase activity
C9I78_19595	COG2198	Histidine kinase
C9I78_19595	COG0784	Response regulator, receiver
C9I78_19600	COG1879	ABC-type sugar transport system periplasmic component
C9I78_19605	COG1803	Methylglyoxal synthase
C9I78_19610	COG0210	DNA helicase
C9I78_19615	COG1289	transmembrane transporter activity
C9I78_19650	COG4206	TonB-dependent receptor
C9I78_19665	COG0789	Transcriptional regulator
C9I78_19670	COG4604	ABC transporter, ATP-binding protein
C9I78_19675	COG4605	iron ion homeostasis
C9I78_19680	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9I78_19685	COG4607	ABC-type enterochelin transport system periplasmic component
C9I78_19710	COG2847	Copper chaperone PCu(A)C
C9I78_19715	COG0443	Heat shock 70 kDa protein
C9I78_19750	COG0625	glutathione transferase activity
C9I78_19765	COG4160	amino acid transport
C9I78_19770	COG4215	(ABC) transporter
C9I78_19775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_19780	COG1126	abc transporter atp-binding protein
C9I78_19810	COG1902	pentaerythritol trinitrate reductase activity
C9I78_19815	COG0109	protoheme IX farnesyltransferase activity
C9I78_19820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C9I78_19825	COG1845	cytochrome c oxidase, subunit III
C9I78_19830	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C9I78_19835	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C9I78_19840	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_19850	COG1024	Enoyl-CoA hydratase
C9I78_19870	COG0183	Belongs to the thiolase family
C9I78_19880	COG1960	acyl-CoA dehydrogenase activity
C9I78_19885	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9I78_19890	COG1024	Enoyl-CoA hydratase
C9I78_19900	COG5413	integral membrane protein
C9I78_19915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C9I78_19925	COG5001	Diguanylate cyclase
C9I78_19930	COG0513	Belongs to the DEAD box helicase family
C9I78_19935	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
C9I78_19950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C9I78_19970	COG0840	transmembrane signaling receptor activity
C9I78_19975	COG1119	ATPase activity
C9I78_19980	COG2200	EAL domain
C9I78_20000	COG0513	Belongs to the DEAD box helicase family
C9I78_20005	COG0523	cobalamin synthesis protein
C9I78_20015	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
C9I78_20025	COG0133	tryptophan synthase activity
C9I78_20030	COG4628	conserved protein (DUF2132)
C9I78_20035	COG0513	Belongs to the DEAD box helicase family
C9I78_20040	COG3530	Putative quorum-sensing-regulated virulence factor
C9I78_20065	COG2154	pterin-4-alpha-carbinolamine dehydratase
C9I78_20070	COG3186	Phenylalanine-4-hydroxylase
C9I78_20075	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9I78_20080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C9I78_20115	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C9I78_20120	COG1454	alcohol dehydrogenase
C9I78_20125	COG2133	pyrroloquinoline quinone binding
C9I78_20135	COG0783	Belongs to the Dps family
C9I78_20140	COG0840	transmembrane signaling receptor activity
C9I78_20150	COG0577	efflux transmembrane transporter activity
C9I78_20150	COG1136	(ABC) transporter
C9I78_20170	COG2199	diguanylate cyclase activity
C9I78_20185	COG3036	rescue of stalled ribosome
C9I78_20190	COG1278	Cold shock
C9I78_20225	COG0545	Peptidyl-prolyl cis-trans isomerase
C9I78_20230	COG0109	protoheme IX farnesyltransferase activity
C9I78_20235	COG1612	heme a metabolic process
C9I78_20260	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C9I78_20270	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C9I78_20275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C9I78_20285	COG1280	lysine exporter protein (LysE YggA)
C9I78_20290	COG2207	Transcriptional regulator
C9I78_20320	COG0697	spore germination
C9I78_20345	COG2814	Major facilitator Superfamily
C9I78_20350	COG0583	DNA-binding transcription factor activity
C9I78_20355	COG5001	Diguanylate cyclase
C9I78_20360	COG0739	heme binding
C9I78_20400	COG0814	amino acid
C9I78_20420	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C9I78_20425	COG1072	(Pantothenic acid kinase))
C9I78_20435	COG1063	alcohol dehydrogenase
C9I78_20440	COG2213	PTS system mannitol-specific
C9I78_20445	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_20465	COG0798	PFAM Bile acid sodium symporter
C9I78_20475	COG1881	PFAM PEBP family protein
C9I78_20485	COG2706	6-phosphogluconolactonase activity
C9I78_20500	COG0840	transmembrane signaling receptor activity
C9I78_20510	COG1131	(ABC) transporter
C9I78_20515	COG0842	Transport permease protein
C9I78_20530	COG3383	formate dehydrogenase (NAD+) activity
C9I78_20555	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C9I78_20575	COG2203	Gaf domain
C9I78_20575	COG2199	diguanylate cyclase activity
C9I78_20585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C9I78_20595	COG2067	long-chain fatty acid transport protein
C9I78_20605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_20620	COG0488	(ABC) transporter
C9I78_20625	COG0589	response to stress
C9I78_20630	COG2249	NAD(P)H dehydrogenase (quinone) activity
C9I78_20650	COG0366	Alpha amylase catalytic
C9I78_20660	COG4934	collagen metabolic process
C9I78_20675	COG0583	DNA-binding transcription factor activity
C9I78_20685	COG0783	Belongs to the Dps family
C9I78_20690	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C9I78_20715	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
C9I78_20715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9I78_20725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C9I78_20735	COG0784	Response regulator, receiver
C9I78_20735	COG0835	chemotaxis
C9I78_20745	COG0748	coenzyme F420 binding
C9I78_20750	COG3721	Heme iron utilization protein
C9I78_20760	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C9I78_20765	COG0811	peptide transport
C9I78_20770	COG0848	biopolymer transport protein
C9I78_20780	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9I78_20785	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
C9I78_20830	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C9I78_20835	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C9I78_20840	COG0633	Ferredoxin
C9I78_20840	COG3217	Mosc domain protein beta barrel domain protein
C9I78_20840	COG3217	Mosc domain protein beta barrel domain protein
C9I78_20840	COG0633	Ferredoxin
C9I78_20850	COG0401	homolog of Blt101
C9I78_20860	COG0418	dihydroorotase activity
C9I78_20865	COG2354	Protein conserved in bacteria
C9I78_20895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C9I78_20895	COG2207	Transcriptional regulator
C9I78_20900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I78_20945	COG0513	Belongs to the DEAD box helicase family
C9I78_20955	COG0583	DNA-binding transcription factor activity
C9I78_20970	COG1902	pentaerythritol trinitrate reductase activity
C9I78_20975	COG1063	alcohol dehydrogenase
C9I78_20985	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_21000	COG3122	Protein conserved in bacteria
C9I78_21020	COG0583	DNA-binding transcription factor activity
C9I78_21030	COG0252	asparaginase activity
C9I78_21035	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C9I78_21040	COG0574	Belongs to the PEP-utilizing enzyme family
C9I78_21040	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C9I78_21060	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C9I78_21065	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C9I78_21080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_21100	COG3706	GGDEF domain
C9I78_21120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C9I78_21150	COG3842	ATPase activity
C9I78_21195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C9I78_21245	COG0583	DNA-binding transcription factor activity
C9I78_21255	COG4948	Mandelate Racemase Muconate Lactonizing
C9I78_21265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C9I78_21290	COG1342	Belongs to the UPF0251 family
C9I78_21300	COG3015	lipoprotein NlpE involved in copper resistance
C9I78_21310	COG3713	MltA-interacting MipA family protein
C9I78_21325	COG0583	DNA-binding transcription factor activity
C9I78_21350	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
C9I78_21360	COG1335	isochorismatase
C9I78_21370	COG0753	catalase activity
C9I78_21380	COG1349	DNA-binding transcription factor activity
C9I78_21385	COG0346	lactoylglutathione lyase activity
C9I78_21390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_21390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_21405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_21410	COG3537	Alpha-1,2-mannosidase
C9I78_21415	COG3537	Alpha-1,2-mannosidase
C9I78_21425	COG3537	Alpha-1,2-mannosidase
C9I78_21430	COG3537	Alpha-1,2-mannosidase
C9I78_21435	COG2070	2-Nitropropane dioxygenase
C9I78_21440	COG0737	Belongs to the 5'-nucleotidase family
C9I78_21450	COG1309	transcriptional regulator
C9I78_21470	COG1280	lysine exporter protein (LysE YggA)
C9I78_21485	COG0459	protein refolding
C9I78_21490	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C9I78_21495	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C9I78_21520	COG1304	FMN binding
C9I78_21540	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_21555	COG1706	bacterial-type flagellum-dependent cell motility
C9I78_21560	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C9I78_21565	COG4786	Flagellar basal body rod
C9I78_21570	COG4787	bacterial-type flagellum-dependent cell motility
C9I78_21575	COG1749	Flagellar hook protein flgE
C9I78_21580	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
C9I78_21585	COG1558	bacterial-type flagellum-dependent cell motility
C9I78_21590	COG1815	bacterial-type flagellum-dependent cell motility
C9I78_21610	COG0741	lytic transglycosylase activity
C9I78_21615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C9I78_21635	COG1760	l-serine dehydratase
C9I78_21660	COG0583	DNA-binding transcription factor activity
C9I78_21675	COG2866	Carboxypeptidase
C9I78_21680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C9I78_21690	COG2990	Protein conserved in bacteria
C9I78_21715	COG3842	ATPase activity
C9I78_21725	COG1840	ABC-type Fe3 transport system, periplasmic component
C9I78_21730	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C9I78_21740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9I78_21745	COG1609	Transcriptional regulator
C9I78_21775	COG3240	lipase activity
C9I78_21785	COG1136	(ABC) transporter
C9I78_21785	COG0577	efflux transmembrane transporter activity
C9I78_21790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C9I78_21795	COG2067	long-chain fatty acid transport protein
C9I78_21805	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C9I78_21820	COG1011	Hydrolase
C9I78_21860	COG0110	maltose O-acetyltransferase activity
C9I78_21865	COG1765	OsmC-like protein
C9I78_21870	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_21870	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C9I78_21885	COG3046	protein related to deoxyribodipyrimidine photolyase
C9I78_21890	COG0415	Belongs to the DNA photolyase family
C9I78_21895	COG3706	GGDEF domain
C9I78_21910	COG0840	transmembrane signaling receptor activity
C9I78_21915	COG3706	GGDEF domain
C9I78_21920	COG3145	DNA-N1-methyladenine dioxygenase activity
C9I78_21930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C9I78_21950	COG3033	Beta-eliminating lyase
C9I78_21960	COG0579	oxidoreductase
C9I78_21990	COG3706	GGDEF domain
C9I78_22000	COG4191	Histidine kinase
C9I78_22035	COG0583	DNA-binding transcription factor activity
C9I78_22045	COG0189	ligase activity
C9I78_22050	COG0189	ligase activity
C9I78_22050	COG4067	protein conserved in archaea
C9I78_22060	COG1166	arginine decarboxylase activity
C9I78_22065	COG0010	Belongs to the arginase family
C9I78_22070	COG2814	Major facilitator Superfamily
C9I78_22075	COG1770	oligopeptidase
C9I78_22090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C9I78_22095	COG1121	(ABC) transporter
C9I78_22100	COG0803	Belongs to the bacterial solute-binding protein 9 family
C9I78_22140	COG0848	biopolymer transport protein
C9I78_22145	COG0811	peptide transport
C9I78_22150	COG0811	peptide transport
C9I78_22170	COG0745	RESPONSE REGULATOR receiver
C9I78_22180	COG0584	glycerophosphoryl diester phosphodiesterase
C9I78_22190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C9I78_22250	COG1901	pseudouridine methyltransferase
C9I78_22255	COG0312	modulator of DNA gyrase
C9I78_22270	COG0351	phosphomethylpyrimidine kinase
C9I78_22275	COG1116	anion transmembrane transporter activity
C9I78_22280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C9I78_22285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C9I78_22290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C9I78_22295	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
C9I78_22300	COG0352	thiamine-phosphate diphosphorylase activity
C9I78_22310	COG0243	molybdopterin cofactor binding
C9I78_22315	COG3005	denitrification pathway
C9I78_22325	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_22340	COG0456	acetyltransferase
C9I78_22360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I78_22365	COG1929	Belongs to the glycerate kinase type-1 family
C9I78_22370	COG2610	gluconate transmembrane transporter activity
C9I78_22375	COG3835	regulator
C9I78_22400	COG0546	phosphoglycolate phosphatase activity
C9I78_22415	COG0583	DNA-binding transcription factor activity
C9I78_22425	COG0583	DNA-binding transcription factor activity
C9I78_22435	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
C9I78_22440	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C9I78_22440	COG3408	Glycogen debranching enzyme
C9I78_22470	COG3047	cAMP biosynthetic process
C9I78_22475	COG1357	PFAM Pentapeptide repeats (8 copies)
C9I78_22505	COG2375	cellular response to nickel ion
C9I78_22510	COG0823	Involved in the tonB-independent uptake of proteins
C9I78_22515	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9I78_22535	COG0800	Aldolase
C9I78_22540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C9I78_22555	COG1917	Cupin 2, conserved barrel domain protein
C9I78_22565	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_22570	COG1414	Transcriptional regulator
C9I78_22585	COG0583	DNA-binding transcription factor activity
C9I78_22590	COG2162	N-hydroxyarylamine O-acetyltransferase activity
C9I78_22595	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C9I78_22610	COG2199	diguanylate cyclase activity
C9I78_22620	COG0561	phosphatase activity
C9I78_22625	COG0583	DNA-binding transcription factor activity
C9I78_22640	COG0564	pseudouridine synthase activity
C9I78_22645	COG0534	Mate efflux family protein
C9I78_22655	COG5001	Diguanylate cyclase
C9I78_22665	COG3123	guanosine phosphorylase activity
C9I78_22705	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
C9I78_22715	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C9I78_22720	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
C9I78_22735	COG2259	Doxx family
C9I78_22740	COG1741	Belongs to the pirin family
C9I78_22760	COG0363	glucosamine-6-phosphate deaminase activity
C9I78_22775	COG0786	glutamate:sodium symporter activity
C9I78_22780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I78_22785	COG1131	(ABC) transporter
C9I78_22795	COG0786	glutamate:sodium symporter activity
C9I78_22830	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C9I78_22840	COG3279	Response regulator of the LytR AlgR family
C9I78_22845	COG3275	phosphorelay sensor kinase activity
C9I78_22865	COG1136	(ABC) transporter
C9I78_22880	COG0772	Belongs to the SEDS family
C9I78_22885	COG0217	transcriptional regulatory protein
C9I78_22910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C9I78_22910	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
C9I78_22920	COG0444	Belongs to the ABC transporter superfamily
C9I78_22925	COG4608	Belongs to the ABC transporter superfamily
C9I78_22955	COG1444	tRNA N-acetyltransferase activity
C9I78_22975	COG3340	Belongs to the peptidase S51 family
C9I78_22980	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C9I78_22985	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9I78_22985	COG1263	PTS System
C9I78_22990	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
C9I78_23010	COG4166	transmembrane transport
C9I78_23060	COG0259	pyridoxamine-phosphate oxidase activity
C9I78_23090	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C9I78_23135	COG1132	(ABC) transporter
C9I78_23145	COG2207	Transcriptional regulator
C9I78_23170	COG0800	Aldolase
C9I78_23180	COG1904	glucuronate isomerase
C9I78_23185	COG0246	Mannitol dehydrogenase
C9I78_23195	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
C9I78_23205	COG2186	Transcriptional regulator
C9I78_23215	COG0513	Belongs to the DEAD box helicase family
C9I78_23220	COG2258	MOSC domain
C9I78_23235	COG1486	melibiose metabolic process
C9I78_23240	COG0583	DNA-binding transcription factor activity
C9I78_23245	COG0840	transmembrane signaling receptor activity
C9I78_23260	COG1595	DNA-templated transcription, initiation
C9I78_23295	COG3634	alkyl hydroperoxide reductase activity
C9I78_23300	COG0450	alkyl hydroperoxide reductase
C9I78_23305	COG1846	Transcriptional regulator
C9I78_23310	COG1764	response to oxidative stress
C9I78_23335	COG2160	L-arabinose isomerase activity
C9I78_23345	COG1069	ribulokinase activity
C9I78_23350	COG1879	ABC-type sugar transport system periplasmic component
C9I78_23355	COG1129	ABC transporter
C9I78_23360	COG1172	Belongs to the binding-protein-dependent transport system permease family
C9I78_23385	COG0745	RESPONSE REGULATOR receiver
C9I78_23395	COG1653	transport
C9I78_23400	COG0019	diaminopimelate decarboxylase activity
C9I78_23405	COG4264	IucA IucC family
C9I78_23430	COG4772	TonB-dependent receptor
C9I78_23435	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C9I78_23440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9I78_23445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C9I78_23450	COG1120	ATPase activity
C9I78_23455	COG0840	transmembrane signaling receptor activity
C9I78_23460	COG0612	Peptidase, M16
C9I78_23470	COG0739	heme binding
C9I78_23480	COG2814	Major facilitator Superfamily
C9I78_23495	COG4580	involved in the transport of maltose and maltodextrins
C9I78_23520	COG2356	endonuclease I
C9I78_23540	COG1982	Orn Lys Arg decarboxylase major
C9I78_23545	COG0531	amino acid
C9I78_23555	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C9I78_23565	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C9I78_23570	COG1162	GTPase activity
C9I78_23575	COG1263	PTS System
C9I78_23575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C9I78_23585	COG1999	signal sequence binding
C9I78_23600	COG2909	trisaccharide binding
C9I78_23615	COG0058	SHG alpha-glucan phosphorylase activity
C9I78_23620	COG1640	4-alpha-glucanotransferase
C9I78_23625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C9I78_23630	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C9I78_23635	COG0366	Alpha amylase catalytic
C9I78_23650	COG3366	ferrous iron transmembrane transporter activity
C9I78_23655	COG0700	Nucleoside recognition
C9I78_23665	COG3339	Conserved Protein
C9I78_23670	COG1301	dicarboxylic acid transport
C9I78_23700	COG0583	DNA-binding transcription factor activity
C9I78_23715	COG0489	protein tyrosine kinase activity
C9I78_23715	COG3206	protein involved in exopolysaccharide biosynthesis
C9I78_23735	COG2095	MarC family integral membrane protein
C9I78_23740	COG4667	esterase of the alpha-beta hydrolase superfamily
C9I78_23745	COG3397	chitin binding
C9I78_23765	COG1686	Belongs to the peptidase S11 family
C9I78_23790	COG0583	DNA-binding transcription factor activity
C9I78_23795	COG4628	conserved protein (DUF2132)
C9I78_23805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C9I78_23815	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C9I78_23820	COG0628	permease
C9I78_23865	COG2814	Major facilitator Superfamily
C9I78_23875	COG0454	-acetyltransferase
C9I78_23885	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9I78_23890	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C9I78_23945	COG1360	Flagellar Motor Protein
C9I78_23950	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C9I78_23955	COG1191	sigma factor activity
C9I78_23960	COG1580	Controls the rotational direction of flagella during chemotaxis
C9I78_23975	COG1516	flagellar protein fliS
C9I78_23980	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C9I78_23990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C9I78_24005	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C9I78_24015	COG1987	bacterial-type flagellum assembly
C9I78_24040	COG2204	response regulator
C9I78_24055	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C9I78_24095	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C9I78_24115	COG0346	lactoylglutathione lyase activity
C9I78_24150	COG0745	RESPONSE REGULATOR receiver
C9I78_24170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C9I78_24180	COG0156	8-amino-7-oxononanoate synthase activity
C9I78_24185	COG1063	alcohol dehydrogenase
C9I78_24225	COG0668	transmembrane transport
C9I78_24235	COG1304	FMN binding
C9I78_24240	COG1620	l-lactate permease
C9I78_24245	COG0583	DNA-binding transcription factor activity
C9I78_24250	COG1505	serine-type exopeptidase activity
C9I78_24255	COG4172	Belongs to the ABC transporter superfamily
C9I78_24265	COG1067	ATP-dependent peptidase activity
C9I78_24295	COG1247	-acetyltransferase
C9I78_24300	COG0437	4 iron, 4 sulfur cluster binding
C9I78_24305	COG0348	domain, Protein
C9I78_24320	COG1122	ATPase activity
C9I78_24325	COG4720	Psort location CytoplasmicMembrane, score
C9I78_24330	COG1566	PFAM secretion protein HlyD family protein
C9I78_24340	COG3706	GGDEF domain
C9I78_24355	COG0813	purine-nucleoside phosphorylase activity
C9I78_24365	COG3272	Protein of unknown function (DUF1722)
C9I78_24370	COG0789	Transcriptional regulator
C9I78_24375	COG0415	Belongs to the DNA photolyase family
C9I78_24380	COG1376	ErfK ybiS ycfS ynhG family protein
C9I78_24380	COG1388	LysM domain
C9I78_24390	COG0513	Belongs to the DEAD box helicase family
C9I78_24395	COG1770	oligopeptidase
C9I78_24400	COG4771	TonB-dependent receptor
C9I78_24425	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C9I78_24430	COG0573	inorganic phosphate transmembrane transporter activity
C9I78_24435	COG0581	inorganic phosphate transmembrane transporter activity
C9I78_24440	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C9I78_24455	COG2304	oxidoreductase activity
C9I78_24475	COG0714	Associated with various cellular activities
C9I78_24485	COG0840	transmembrane signaling receptor activity
C9I78_24495	COG2197	response regulator
C9I78_24545	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
C9I78_24550	COG1120	ATPase activity
C9I78_24555	COG4774	siderophore transport
C9I78_24560	COG1132	(ABC) transporter
C9I78_24565	COG5002	protein histidine kinase activity
C9I78_24575	COG0569	domain protein
C9I78_24580	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C9I78_24590	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
C9I78_24595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9I78_24610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_24610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_24610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C9I78_24615	COG2207	Transcriptional regulator
C9I78_24625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_24630	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C9I78_24635	COG2084	Dehydrogenase
C9I78_24640	COG0753	catalase activity
C9I78_24650	COG2130	NADP-dependent
C9I78_24655	COG1309	transcriptional regulator
C9I78_24720	COG3842	ATPase activity
C9I78_24730	COG1175	transmembrane transport
C9I78_24735	COG3833	ABC-type maltose transport systems, permease component
C9I78_24755	COG3746	phosphate-selective porin O and P
C9I78_24770	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_24795	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C9I78_24805	COG0625	glutathione transferase activity
C9I78_24820	COG1686	Belongs to the peptidase S11 family
C9I78_24840	COG0678	peroxiredoxin activity
C9I78_24840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C9I78_24845	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C9I78_24865	COG1278	Cold shock
C9I78_24870	COG1741	Belongs to the pirin family
C9I78_24875	COG4667	esterase of the alpha-beta hydrolase superfamily
C9I78_24885	COG1846	Transcriptional regulator
C9I78_24910	COG0673	inositol 2-dehydrogenase activity
C9I78_24915	COG2194	sulfuric ester hydrolase activity
C9I78_24920	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C9I78_24930	COG2205	protein histidine kinase activity
C9I78_24935	COG0745	RESPONSE REGULATOR receiver
C9I78_24940	COG4221	oxidoreductase activity
C9I78_24960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C9I78_24980	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C9I78_24990	COG2814	Major facilitator Superfamily
C9I78_25005	COG1418	mRNA catabolic process
C9I78_25015	COG0402	S-adenosylhomocysteine deaminase activity
C9I78_25020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C9I78_25030	COG2239	Acts as a magnesium transporter
C9I78_25035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C9I78_25040	COG1566	PFAM secretion protein HlyD family protein
C9I78_25065	COG0745	RESPONSE REGULATOR receiver
C9I78_25070	COG2205	protein histidine kinase activity
C9I78_25085	COG0531	amino acid
C9I78_25120	COG5002	protein histidine kinase activity
C9I78_25120	COG2205	protein histidine kinase activity
C9I78_25120	COG0784	Response regulator, receiver
C9I78_25125	COG0673	inositol 2-dehydrogenase activity
C9I78_25130	COG0534	Mate efflux family protein
C9I78_25140	COG2926	Belongs to the UPF0265 family
C9I78_25155	COG3132	Protein of unknown function, DUF480
C9I78_25160	COG2827	Endonuclease containing a URI domain
C9I78_25165	COG1879	ABC-type sugar transport system periplasmic component
C9I78_25170	COG0784	Response regulator, receiver
C9I78_25170	COG2205	protein histidine kinase activity
C9I78_25180	COG1566	PFAM secretion protein HlyD family protein
C9I78_25200	COG1522	sequence-specific DNA binding
C9I78_25230	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9I78_25235	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C9I78_25255	COG0183	Belongs to the thiolase family
C9I78_25275	COG3005	denitrification pathway
C9I78_25285	COG0243	molybdopterin cofactor binding
C9I78_25295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C9I78_25300	COG3850	Histidine kinase
C9I78_25305	COG2197	response regulator
C9I78_25320	COG2195	Cleaves the N-terminal amino acid of tripeptides
C9I78_25340	COG0840	transmembrane signaling receptor activity
C9I78_25350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C9I78_25365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C9I78_25370	COG2814	Major facilitator Superfamily
C9I78_25380	COG0840	transmembrane signaling receptor activity
C9I78_25385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C9I78_25390	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C9I78_25420	COG2897	thiosulfate sulfurtransferase activity
C9I78_25440	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C9I78_25450	COG0302	gtp cyclohydrolase
C9I78_25455	COG1914	H( )-stimulated, divalent metal cation uptake system
C9I78_25465	COG0038	chloride channel
C9I78_25480	COG4989	oxidoreductase activity
C9I78_25495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C9I78_25495	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C9I78_25500	COG0516	GMP reductase activity
C9I78_25505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C9I78_25575	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C9I78_25575	COG0674	pyruvate-flavodoxin oxidoreductase activity
C9I78_25580	COG1013	pyruvate-flavodoxin oxidoreductase activity
C9I78_25585	COG3474	cytochrome
C9I78_25595	COG0789	Transcriptional regulator
C9I78_25600	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C9I78_25605	COG0384	phenazine biosynthesis protein PhzF
C9I78_25615	COG1294	oxidase, subunit
C9I78_25620	COG1271	oxidase subunit
C9I78_25625	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C9I78_25630	COG0110	maltose O-acetyltransferase activity
C9I78_25640	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C9I78_25640	COG3264	Mechanosensitive ion channel
C9I78_25655	COG3850	Histidine kinase
C9I78_25655	COG2205	protein histidine kinase activity
C9I78_25655	COG4999	Histidine kinase
C9I78_25655	COG3437	response regulator, receiver
C9I78_25675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C9I78_25680	COG1960	acyl-CoA dehydrogenase activity
C9I78_25690	COG0183	Belongs to the thiolase family
C9I78_25700	COG1960	acyl-CoA dehydrogenase activity
C9I78_25705	COG1024	Enoyl-CoA hydratase
C9I78_25720	COG1028	Short-chain dehydrogenase reductase Sdr
C9I78_25730	COG3706	GGDEF domain
C9I78_25735	COG1309	transcriptional regulator
C9I78_25740	COG1012	belongs to the aldehyde dehydrogenase family
C9I78_25755	COG4176	ABC-type proline glycine betaine transport system permease component
C9I78_25760	COG4175	Glycine betaine
C9I78_25760	COG0517	IMP dehydrogenase activity
C9I78_25775	COG0330	HflC and HflK could
C9I78_25785	COG3300	MHYT domain
C9I78_25785	COG5001	Diguanylate cyclase
C9I78_25805	COG2205	protein histidine kinase activity
C9I78_25805	COG0784	Response regulator, receiver
C9I78_25825	COG4974	Belongs to the 'phage' integrase family
C9I78_25845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C9I78_25900	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
C9I78_25940	COG0582	viral genome integration into host DNA
C9I78_25980	COG2189	Belongs to the N(4) N(6)-methyltransferase family
C9I78_26000	COG3706	GGDEF domain
C9I78_26030	COG2003	Belongs to the UPF0758 family
C9I78_26055	COG2003	Belongs to the UPF0758 family
C9I78_26075	COG4962	Type ii secretion system protein e
C9I78_26150	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C9I78_26170	COG0681	Belongs to the peptidase S26 family
C9I78_26185	COG2948	multi-organism process
C9I78_26200	COG3701	Conjugal transfer protein
C9I78_26220	COG3451	type IV secretory pathway VirB4
C9I78_26245	COG1192	Involved in chromosome partitioning
C9I78_26280	COG0419	ATPase involved in DNA repair
C9I78_26305	COG1192	Involved in chromosome partitioning
C9I78_26350	COG5268	conjugation
C9I78_26355	COG3451	type IV secretory pathway VirB4
C9I78_26365	COG4962	Type ii secretion system protein e
C9I78_26380	COG3504	Conjugal transfer protein
C9I78_26415	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB