locus-tag	class	description
DA442_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
DA442_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
DA442_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
DA442_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DA442_00040	ENOG4108ZNX	Heat shock protein
DA442_00045	ENOG4105JKW	Valine--pyruvate aminotransferase
DA442_00050	ENOG4107T9C	Alpha amylase catalytic region
DA442_00055	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
DA442_00060	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
DA442_00075	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
DA442_00090	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
DA442_00095	ENOG4105CHU	acetyl-coa acetyltransferase
DA442_00100	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DA442_00105	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
DA442_00110	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
DA442_00115	ENOG4108RR8	protoporphyrinogen oxidase
DA442_00160	ENOG4105EMY	transcriptional regulator
DA442_00165	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
DA442_00170	ENOG4105W0Z	cytoplasmic protein
DA442_00180	ENOG4105BZS	acriflavin resistance protein
DA442_00185	ENOG410624X	efflux transporter, rnd family, mfp subunit
DA442_00190	ENOG41067SE	Tetr family transcriptional regulator
DA442_00195	ENOG4105C4R	Atp-dependent dna helicase
DA442_00200	ENOG4105MPD	Cytochrome
DA442_00235	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
DA442_00250	ENOG4108JQ6	ABC transporter
DA442_00255	ENOG4105DEF	Extracellular solute-binding protein, family 5
DA442_00260	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DA442_00265	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DA442_00300	ENOG4105D9P	serine threonine protein kinase
DA442_00305	ENOG4105DIQ	Transcriptional regulator
DA442_00310	ENOG41064T2	transcriptional regulator, lysR family
DA442_00315	ENOG41090TI	Catalyzes the excretion of spermidine (By similarity)
DA442_00320	ENOG4108ZBZ	Catalyzes the excretion of spermidine (By similarity)
DA442_00325	ENOG4105C01	Dihydroxy-acid dehydratase
DA442_00330	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
DA442_00335	ENOG4105C6Z	Gluconate
DA442_00340	ENOG4108UHU	Aldolase
DA442_00345	ENOG4107U5R	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
DA442_00350	ENOG4107RSM	transcriptional regulator
DA442_00355	ENOG4105DC8	reductase
DA442_00360	ENOG4105D6S	protein involved in catabolism of external DNA
DA442_00370	ENOG4105DGW	oligopeptidase A
DA442_00375	ENOG4108VVK	transcriptional Regulator, AsnC
DA442_00380	ENOG4105BZU	Histidine kinase
DA442_00385	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
DA442_00395	ENOG4105EMK	carboxylate amino acid amine transporter
DA442_00400	ENOG4108M6U	Universal stress protein A
DA442_00405	ENOG41090A1	ferritin
DA442_00410	ENOG4108V6B	universal stress protein B
DA442_00415	ENOG4105CBX	hi0933 family
DA442_00420	ENOG4108JUA	Transcriptional regulator
DA442_00425	ENOG4105K3G	Periplasmic Protein
DA442_00445	ENOG4107TE5	Lipid kinase
DA442_00475	ENOG4105DSF	transport protein
DA442_00480	ENOG4105BZU	Histidine kinase
DA442_00490	ENOG4105CGY	Dna recombination protein
DA442_00495	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
DA442_00500	ENOG4105JC1	sterol-binding domain protein
DA442_00505	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
DA442_00510	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
DA442_00515	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
DA442_00520	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
DA442_00530	ENOG4105F8V	Hydrolase, tatD family
DA442_00540	ENOG4105D52	delta-aminolevulinic acid dehydratase
DA442_00555	ENOG4105C2M	dna polymerase I
DA442_00565	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
DA442_00570	ENOG4106RE7	Cytochrome
DA442_00590	ENOG4105ZR3	A GTPase-activating protein (GAP) that modifies Der EngA GTPase function. May play a role in ribosome biogenesis (By similarity)
DA442_00595	ENOG4105XCT	Protein of unknown function (DUF2489)
DA442_00600	ENOG4105D4P	Coproporphyrinogen iii oxidase
DA442_00605	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
DA442_00610	ENOG4105BZU	Histidine kinase
DA442_00615	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DA442_00620	ENOG4105CUX	Signal transduction histidine kinase
DA442_00630	ENOG4105C5F	glutamine synthetase
DA442_00660	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
DA442_00665	ENOG4105SUU	thioesterase domain
DA442_00675	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
DA442_00680	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
DA442_00685	ENOG4105VEJ	Heat shock protein
DA442_00690	ENOG4108XKW	General secretion pathway protein C
DA442_00700	ENOG4107QHF	type ii secretion system protein e
DA442_00705	ENOG4105D7Q	type ii secretion system
DA442_00710	ENOG4108VAU	general secretion pathway protein G
DA442_00715	ENOG4105VWV	general secretion pathway protein h
DA442_00720	ENOG4105X5Z	General secretion pathway protein I
DA442_00725	ENOG4108WWZ	General secretion pathway protein J
DA442_00730	ENOG4108RTD	type II secretion system protein K
DA442_00735	ENOG4108BY5	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
DA442_00740	ENOG4105U1E	general secretion pathway protein M
DA442_00745	ENOG4105PIC	general secretion pathway protein N
DA442_00750	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
DA442_00755	ENOG4107RK2	ADP-ribose diphosphatase NudE
DA442_00760	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
DA442_00765	ENOG4105MJ2	Competence protein
DA442_00770	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
DA442_00780	ENOG4105BZM	domain protein
DA442_00790	ENOG4108RRZ	Transcription elongation factor GreB
DA442_00800	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
DA442_00805	ENOG4105E0F	Histidine kinase
DA442_00810	ENOG4105C2W	permease
DA442_00820	ENOG4105CB5	ATP-dependent DNA helicase recG
DA442_00825	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
DA442_00830	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
DA442_00835	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
DA442_00840	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
DA442_00855	ENOG4109015	Biopolymer transport protein exbD tolR
DA442_00875	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
DA442_00885	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
DA442_00890	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
DA442_00895	ENOG4107QRA	Extracellular solute-binding protein, family 5
DA442_00905	ENOG4108JQ7	(ABC) transporter
DA442_00980	ENOG4105DSJ	YicC domain protein
DA442_00985	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
DA442_00990	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
DA442_00995	ENOG4105D1S	lipid A biosynthesis
DA442_01000	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
DA442_01005	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
DA442_01015	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_01020	ENOG4105W5Q	DNA repair protein (RadC
DA442_01025	ENOG4105KDC	50s ribosomal protein l28
DA442_01035	ENOG4108I6E	Sulfatase
DA442_01045	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
DA442_01050	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
DA442_01055	ENOG4108JMC	lipopolysaccharide core biosynthesis protein
DA442_01065	ENOG4106WTF	Glycosyl transferase, family 2
DA442_01070	ENOG4105DKP	glycosyl transferase, family 9
DA442_01075	ENOG41080IJ	Diacylglycerol kinase
DA442_01080	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
DA442_01090	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
DA442_01095	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
DA442_01110	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
DA442_01155	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
DA442_01160	ENOG4105XA0	heptosyltransferase ii
DA442_01165	ENOG4105NWR	lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase
DA442_01170	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
DA442_01175	ENOG4105E3R	(LipO)protein
DA442_01265	ENOG4105CG5	Glycosyl transferase (Group 1
DA442_01270	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
DA442_01275	ENOG4105C30	Nad-dependent epimerase dehydratase
DA442_01280	ENOG4105FGF	GDP-mannose mannosyl hydrolase
DA442_01285	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
DA442_01290	ENOG4106ECQ	phosphomannomutase
DA442_01295	ENOG4105EIP	mannose-6-phosphate isomerase
DA442_01310	ENOG4105D3Q	Sugar transferase
DA442_01330	ENOG4105CY0	Metallo-Beta-Lactamase
DA442_01335	ENOG4105CP7	Triose-phosphate isomerase
DA442_01360	ENOG4105CBT	Fructose-1,6-bisphosphatase
DA442_01370	ENOG41065UX	Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA (By similarity)
DA442_01375	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
DA442_01380	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
DA442_01385	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
DA442_01390	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
DA442_01400	ENOG4105ETE	Transcriptional regulator (LacI family
DA442_01405	ENOG4105C25	Primosomal protein n'
DA442_01415	ENOG4105VFB	Binds the 23S rRNA (By similarity)
DA442_01420	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
DA442_01425	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
DA442_01430	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
DA442_01435	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
DA442_01440	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DA442_01445	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
DA442_01450	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
DA442_01455	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
DA442_01460	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
DA442_01465	ENOG41083MP	50s ribosomal protein l29
DA442_01470	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
DA442_01475	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
DA442_01480	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
DA442_01485	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DA442_01490	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
DA442_01495	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
DA442_01500	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
DA442_01510	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
DA442_01515	ENOG4105VPB	50S ribosomal protein L30
DA442_01520	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
DA442_01525	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
DA442_01535	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DA442_01540	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
DA442_01545	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
DA442_01550	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DA442_01555	ENOG4108ZT0	50S ribosomal protein l17
DA442_01565	ENOG4108V1T	peptidylprolyl cis-trans isomerase
DA442_01575	ENOG4107YB6	acetyltransferase, (GNAT) family
DA442_01580	ENOG4105C1J	atp-dependent rna helicase
DA442_01590	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
DA442_01595	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DA442_01600	ENOG4105C11	sulfate adenylyltransferase), subunit 2
DA442_01605	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
DA442_01620	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
DA442_01640	ENOG4108I0Y	(ABC) transporter
DA442_01660	ENOG41061GZ	Protein of unknown function (DUF1107)
DA442_01665	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DA442_01675	ENOG4105MA0	exported protein
DA442_01680	ENOG41066HZ	AIG2-like family
DA442_01690	ENOG4105F0N	pyrophosphate phospho-hydrolase
DA442_01695	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DA442_01705	ENOG4105DFU	Cell wall formation (By similarity)
DA442_01710	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
DA442_01715	ENOG4105DP9	ABC transporter
DA442_01720	ENOG4106SMU	thiamine transporter membrane protein
DA442_01725	ENOG4107T0D	ABC, transporter
DA442_01755	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
DA442_01760	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
DA442_01770	ENOG4105EAH	synthase
DA442_01775	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
DA442_01780	ENOG4105K46	50S ribosomal protein l27
DA442_01785	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DA442_01790	ENOG4105DWK	Membrane
DA442_01800	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
DA442_01805	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
DA442_01810	ENOG4105NWN	ApaG protein
DA442_01815	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
DA442_01820	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
DA442_01825	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
DA442_01830	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
DA442_01835	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
DA442_01845	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DA442_01850	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
DA442_01855	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
DA442_01860	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
DA442_01885	ENOG41064T2	transcriptional regulator, lysR family
DA442_01890	ENOG4108IQE	Amp-dependent synthetase and ligase
DA442_01895	ENOG4105C7K	acetolactate synthase
DA442_01900	ENOG4108ZP8	Acetolactate synthase small subunit
DA442_01905	ENOG4105BZU	Histidine kinase
DA442_01915	ENOG4105CA9	Pyruvate kinase
DA442_01925	ENOG410804X	Transcriptional regulator
DA442_01930	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
DA442_01945	ENOG4105GR3	Histidine kinase
DA442_01950	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
DA442_01955	ENOG4105E61	Mannitol repressor protein
DA442_01960	ENOG4107SQ3	mannitol-1-phosphate 5-dehydrogenase
DA442_01965	ENOG4105CTS	PTS system mannitol-specific
DA442_02010	ENOG4105D01	(LipO)protein
DA442_02015	ENOG4105DFP	Integrase
DA442_02085	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DA442_02090	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
DA442_02095	ENOG4105KTH	gatB Yqey
DA442_02100	ENOG4105VCC	30S ribosomal protein S21
DA442_02105	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DA442_02110	ENOG4108WC5	Alpha Beta Hydrolase Fold protein
DA442_02115	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
DA442_02120	ENOG4107ZVW	dihydroneopterin aldolase
DA442_02125	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DA442_02130	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
DA442_02135	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
DA442_02150	ENOG4106MWK	domain protein
DA442_02155	ENOG4105CJ3	phosphate transporter
DA442_02160	ENOG4107IX6	phosphate transport regulator
DA442_02165	ENOG4105I7R	Adenylate cyclase
DA442_02175	ENOG4108NVR	Methyl-accepting chemotaxis
DA442_02180	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
DA442_02185	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
DA442_02190	ENOG4105DFG	type I secretion outer membrane protein
DA442_02195	ENOG41087AY	ADP-Ribose pyrophosphatase
DA442_02200	ENOG4108SX3	cytoplasmic protein
DA442_02205	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
DA442_02210	ENOG4105IPS	esterase
DA442_02215	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DA442_02220	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DA442_02225	ENOG4105C0H	protease
DA442_02230	ENOG4105C0H	protease
DA442_02235	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
DA442_02245	ENOG4105D6Z	AFG1 family ATPase
DA442_02255	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
DA442_02260	ENOG4108UJD	30S ribosomal protein S9
DA442_02265	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DA442_02270	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
DA442_02275	ENOG4105EIX	cytochrome c1
DA442_02280	ENOG4107MKT	Stringent starvation protein a
DA442_02285	ENOG4105KB2	stringent starvation protein b
DA442_02290	ENOG4105W4M	Transport-associated protein
DA442_02295	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
DA442_02300	ENOG41082RQ	UPF0102 protein
DA442_02310	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
DA442_02325	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
DA442_02330	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
DA442_02335	ENOG4105CJN	penicillin-binding protein
DA442_02340	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
DA442_02345	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
DA442_02350	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
DA442_02355	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
DA442_02365	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
DA442_02370	ENOG4105DFU	Cell wall formation (By similarity)
DA442_02375	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
DA442_02380	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
DA442_02385	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
DA442_02390	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DA442_02400	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DA442_02405	ENOG4105M6F	mutator MutT protein
DA442_02410	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
DA442_02415	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
DA442_02420	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
DA442_02435	ENOG4105EJ9	Membrane
DA442_02440	ENOG4105VP0	transcriptional regulator, lysR family
DA442_02445	ENOG4105EN6	Membrane
DA442_02450	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
DA442_02455	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
DA442_02460	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
DA442_02470	ENOG4105BZ8	glutamate synthase
DA442_02475	ENOG4105CBC	glutamate synthase
DA442_02490	ENOG4105N5T	Radical SAM Protein
DA442_02500	ENOG4105BZU	Histidine kinase
DA442_02510	ENOG41065U4	response regulator
DA442_02525	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
DA442_02540	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
DA442_02545	ENOG4105D98	threonine synthase
DA442_02550	ENOG4108VKA	Acts as a radical domain for damaged PFL and possibly other radical proteins (By similarity)
DA442_02555	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
DA442_02565	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
DA442_02580	ENOG4105BZG	amino acid carrier protein
DA442_02585	ENOG4105D1Q	UPF0246 protein
DA442_02590	ENOG4105C1J	atp-dependent rna helicase
DA442_02595	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
DA442_02600	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
DA442_02605	ENOG41071R3	Low-potential electron donor to a number of redox enzymes (By similarity)
DA442_02610	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DA442_02615	ENOG4105T95	Thiol disulfide interChange protein
DA442_02620	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
DA442_02630	ENOG4105CRK	lysyL-tRNA synthetase
DA442_02635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DA442_02655	ENOG4105IRT	Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair (By similarity)
DA442_02665	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
DA442_02680	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
DA442_02685	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
DA442_02700	ENOG41063Z6	transcriptional regulator, lysR family
DA442_02710	ENOG41080HT	Transcriptional regulator, arsr family
DA442_02720	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
DA442_02725	ENOG4105CJR	Integral membrane protein (MviN
DA442_02730	ENOG4105DTN	riboflavin biosynthesis protein ribF
DA442_02735	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
DA442_02740	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
DA442_02745	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
DA442_02750	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
DA442_02755	ENOG4108NEV	two component transcriptional regulator, LytTR family
DA442_02760	ENOG4108HRK	Histidine kinase
DA442_02780	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DA442_02790	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
DA442_02795	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
DA442_02800	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
DA442_02805	ENOG4105DR5	peptidase
DA442_02825	ENOG4107SC1	transglycosylase
DA442_02830	ENOG4105R9M	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity)
DA442_02835	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
DA442_02845	ENOG4108WPH	sigma 54 modulation protein ribosomal protein S30EA
DA442_02850	ENOG4105E4C	Lytic transglycosylase catalytic
DA442_02855	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DA442_02860	ENOG4105C34	Pseudouridine synthase
DA442_02865	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
DA442_02870	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DA442_02930	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
DA442_02935	ENOG4105CFP	Peptidase U32
DA442_02940	ENOG4105DH7	May be involved in recombination (By similarity)
DA442_02950	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DA442_02955	ENOG4105BZU	Histidine kinase
DA442_02965	ENOG4105C9X	ppx gppa phosphatase
DA442_02970	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
DA442_02980	ENOG4105E2Z	phosphate ABC transporter (Permease
DA442_02985	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DA442_02995	ENOG4105CSR	polyphosphate kinase 2
DA442_03000	ENOG4106N3A	copper homeostasis protein cutc
DA442_03010	ENOG4105D3R	alkyl hydroperoxide reductase
DA442_03015	ENOG4105C5Q	Transcriptional regulator
DA442_03025	ENOG4107QP3	malate synthase g
DA442_03030	ENOG4108I9X	Isocitrate lyase
DA442_03035	ENOG4105W87	Cbs domain
DA442_03050	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
DA442_03055	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
DA442_03060	ENOG4105VIE	preprotein translocase, subunit YajC
DA442_03065	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DA442_03070	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DA442_03080	ENOG4105ECY	inositol monophosphatase
DA442_03085	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
DA442_03090	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
DA442_03095	ENOG4105C3J	Cysteine desulfurase
DA442_03100	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
DA442_03105	ENOG4108Z4V	iron-sulfur cluster assembly
DA442_03110	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
DA442_03115	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
DA442_03120	ENOG4108ZIT	Ferredoxin, 2FE-2S
DA442_03125	ENOG4105WVQ	Fe-S assembly protein IscX
DA442_03130	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
DA442_03135	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
DA442_03140	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DA442_03155	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
DA442_03160	ENOG4105CUT	histidyl-tRNA synthetase
DA442_03165	ENOG4105N21	Membrane
DA442_03170	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
DA442_03175	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
DA442_03190	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DA442_03195	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DA442_03200	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
DA442_03205	ENOG4107S6Z	Na H antiporter
DA442_03215	ENOG4106HK8	GPR1 FUN34 yaaH family protein
DA442_03225	ENOG4105BZG	amino acid carrier protein
DA442_03230	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
DA442_03260	ENOG4108IQK	o-acetylhomoserine
DA442_03265	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DA442_03285	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
DA442_03290	ENOG4105ETT	transcriptional Regulator, LysR family
DA442_03310	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
DA442_03315	ENOG4108Z1B	Cyclase dehydrase
DA442_03320	ENOG4105VDB	UPF0125 protein
DA442_03325	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
DA442_03330	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
DA442_03340	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
DA442_03345	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DA442_03355	ENOG4105CFG	Acts as a chaperone (By similarity)
DA442_03360	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DA442_03400	ENOG4105CFC	Transporter
DA442_03405	ENOG4108Z6B	deaminase
DA442_03415	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
DA442_03420	ENOG4108ETH	Formylglycinamide ribotide synthetase
DA442_03445	ENOG4105CIN	aminoacyl-histidine dipeptidase
DA442_03450	ENOG4105C7N	Xanthine uracil vitamin C permease
DA442_03455	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
DA442_03460	ENOG4108DJV	Fermentation respiration switch protein
DA442_03465	ENOG4108UVK	Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32 (By similarity)
DA442_03470	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
DA442_03475	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
DA442_03480	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
DA442_03485	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
DA442_03500	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
DA442_03505	ENOG4107YIM	Involved in the transcription termination process (By similarity)
DA442_03510	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
DA442_03515	ENOG4108ZAI	phosphatidylglycerophosphatase a
DA442_03520	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
DA442_03525	ENOG4105CTB	Polyprenyl synthetase
DA442_03530	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
DA442_03535	ENOG4105E14	MotA TolQ exbB proton channel
DA442_03540	ENOG4107QKZ	Ompa motb domain protein
DA442_03545	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
DA442_03550	ENOG4105ETT	transcriptional Regulator, LysR family
DA442_03560	ENOG4105M08	Membrane
DA442_03565	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
DA442_03575	ENOG4105CIQ	May have a role in processing of nucleic acids. It is probably not an exonuclease
DA442_03580	ENOG4105EWT	decarboxylase family
DA442_03585	ENOG4105BZU	Histidine kinase
DA442_03595	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
DA442_03600	ENOG4108T6E	Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function (By similarity)
DA442_03605	ENOG4105EXF	Zn-ribbon-containing, possibly nucleic-acid-binding protein
DA442_03610	ENOG4105D01	(LipO)protein
DA442_03615	ENOG4108UMI	ABC transporter, permease
DA442_03620	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
DA442_03630	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
DA442_03635	ENOG4105D4X	repressor
DA442_03640	ENOG4105C5Y	PTS System
DA442_03645	ENOG4105CG3	alpha amylase, catalytic region
DA442_03660	ENOG4108JYZ	YitT family
DA442_03665	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DA442_03670	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
DA442_03675	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
DA442_03680	ENOG4108Z43	UPF0250 protein
DA442_03685	ENOG4105DZ1	carboxypeptidase
DA442_03690	ENOG4105K6T	rare lipoprotein A
DA442_03695	ENOG4105CNI	cell division protein FtsW
DA442_03700	ENOG4105CJN	penicillin-binding protein
DA442_03705	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
DA442_03710	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
DA442_03715	ENOG4105DJF	DNA polymerase III, delta' subunit
DA442_03720	ENOG4108U2H	Rare lipoprotein B
DA442_03725	ENOG4105C8T	Leucyl-tRNA synthetase
DA442_03730	ENOG4107PAI	alpha helical protein
DA442_03735	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
DA442_03740	ENOG4108JU5	Magnesium and cobalt efflux protein
DA442_03745	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
DA442_03750	ENOG4105C9A	Phoh family
DA442_03755	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
DA442_03765	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
DA442_03880	ENOG4105C3G	gtp-binding protein
DA442_03885	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
DA442_03890	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
DA442_03895	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
DA442_03900	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
DA442_03905	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
DA442_03910	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
DA442_03915	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
DA442_03920	ENOG4108YY7	Invasion gene expression up-regulator SirB
DA442_03925	ENOG41063JG	Transcriptional regulator
DA442_03930	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
DA442_03935	ENOG4105CGH	5'-nucleotidase
DA442_03940	ENOG4108Z66	YbaK ebsC protein
DA442_03945	ENOG4105FE9	pseudouridine synthase
DA442_03950	ENOG4108DG9	Smr protein MutS2
DA442_03975	ENOG4105E2D	ec 3.2.1.52
DA442_03990	ENOG4105C59	p-type ATPase
DA442_04000	ENOG41081QG	Porin Gram-negative type
DA442_04010	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
DA442_04020	ENOG4105UYK	outer membrane protein a
DA442_04070	ENOG4107R88	Chemotaxis protein (CheV)
DA442_04075	ENOG4105BZU	Histidine kinase
DA442_04080	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
DA442_04085	ENOG4108ZC9	flagellar basal-body rod protein flgc
DA442_04090	ENOG4105W00	Flagellar hook capping protein
DA442_04095	ENOG4105BZE	flagellar hook protein, FlgE
DA442_04105	ENOG4108KPB	Flagellar basal-body rod protein FlgF
DA442_04110	ENOG4105CGA	flagellar basal-body rod protein FlgG
DA442_04115	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
DA442_04120	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
DA442_04125	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
DA442_04135	ENOG4105DTJ	flagellar hook-associated protein
DA442_04145	ENOG4105I03	Flagellin
DA442_04155	ENOG4105I03	Flagellin
DA442_04170	ENOG4105C5Y	PTS System
DA442_04180	ENOG4105KZ7	phosphocarrier protein hpr
DA442_04190	ENOG4105C6T	cysteine synthase
DA442_04195	ENOG4105EXN	Sulfate transport protein CysZ
DA442_04200	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
DA442_04205	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
DA442_04235	ENOG4107QX8	SPFH domain, Band 7 family protein
DA442_04240	ENOG4107QR8	Thioredoxin
DA442_04250	ENOG4105E1F	short-chain dehydrogenase reductase
DA442_04255	ENOG4105ECP	epimerase
DA442_04285	ENOG4108RE9	Phosphodiesterase
DA442_04305	ENOG4108DQ1	activator toxR
DA442_04310	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
DA442_04315	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
DA442_04320	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
DA442_04325	ENOG4105DUX	Transporter
DA442_04330	ENOG4105MDZ	Transcriptional activator rfaH
DA442_04335	ENOG4105CAQ	asparagine synthetase
DA442_04340	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
DA442_04345	ENOG4105E2R	ROK family
DA442_04350	ENOG4105CE4	GlcNAc 6-P deacetylase
DA442_04360	ENOG4105CI1	PTS System
DA442_04365	ENOG4105CX6	glutaminyL-tRNA synthetase
DA442_04370	ENOG41090R7	Ferric uptake
DA442_04380	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
DA442_04390	ENOG4105EV9	Alpha Beta Hydrolase
DA442_04400	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
DA442_04410	ENOG4107QNR	UPF0135 protein
DA442_04415	ENOG4105BZN	citrate synthase
DA442_04420	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
DA442_04425	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
DA442_04430	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
DA442_04435	ENOG4105E33	succinate dehydrogenase
DA442_04440	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
DA442_04445	ENOG4105C7S	Dehydrogenase
DA442_04450	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
DA442_04455	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
DA442_04460	ENOG4105FAV	ABC, transporter
DA442_04465	ENOG4105FDK	ABC transporter
DA442_04470	ENOG4105NXV	High-affinity zinc uptake system protein
DA442_04485	ENOG4105XFK	Ferrous iron transport protein A
DA442_04490	ENOG4105CE1	Ferrous iron transport protein b
DA442_04505	ENOG4105C75	arginyL-tRNA synthetase
DA442_04515	ENOG4106ZCM	YecM protein
DA442_04520	ENOG4105CIY	formyltetrahydrofolate deformylase
DA442_04525	ENOG4105DVT	helicase
DA442_04530	ENOG41072GX	Peptidase M22 Glycoprotease
DA442_04545	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
DA442_04550	ENOG4105CEY	Amp-dependent synthetase and ligase
DA442_04555	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
DA442_04560	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
DA442_04565	ENOG4107QMS	site-determining protein
DA442_04570	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
DA442_04575	ENOG4105VNG	YcgL domain-containing protein
DA442_04580	ENOG4105CVE	Lytic murein transglycosylase
DA442_04585	ENOG4105CC0	LysR family Transcriptional regulator
DA442_04590	ENOG4105D9N	nucleoside
DA442_04595	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
DA442_04610	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DA442_04615	ENOG4105C2D	reductase
DA442_04625	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DA442_04650	ENOG4105C84	Histidine ammonia-lyase
DA442_04655	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
DA442_04660	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
DA442_04680	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DA442_04720	ENOG4105C1J	atp-dependent rna helicase
DA442_04725	ENOG4107ZYR	domain protein
DA442_04750	ENOG4105CNG	UPF0061 protein
DA442_04755	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
DA442_04760	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
DA442_04765	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
DA442_04780	ENOG4105CQZ	Histidine kinase
DA442_04785	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
DA442_04790	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
DA442_04795	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
DA442_04800	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
DA442_04805	ENOG4105K70	DNA-binding protein
DA442_04810	ENOG4105EIN	peptidylprolyl cis-trans isomerase
DA442_04815	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
DA442_04830	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
DA442_04835	ENOG4105DK2	UPF0207 protein
DA442_04840	ENOG4105CHM	Aminotransferase
DA442_04845	ENOG4105E4F	Isochorismate synthase
DA442_04850	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
DA442_04855	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
DA442_04860	ENOG4108IPT	Naphthoate synthase
DA442_04865	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
DA442_04870	ENOG4105CEY	Amp-dependent synthetase and ligase
DA442_04880	ENOG4105HMI	Membrane
DA442_04935	ENOG4105BZS	acriflavin resistance protein
DA442_04965	ENOG4108XM1	transcriptional regulator AsnC family
DA442_04975	ENOG4105C29	acyl-CoA thioesterase
DA442_04980	ENOG4108MNP	Glycoprotein polysaccharide metabolism
DA442_04995	ENOG4108KHX	Diguanylate cyclase
DA442_05010	ENOG4108Z4U	Ferredoxin
DA442_05015	ENOG4105DZ0	fad dependent oxidoreductase
DA442_05025	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DA442_05035	ENOG4107SXA	Phosphorylase
DA442_05050	ENOG4108NVR	Methyl-accepting chemotaxis
DA442_05055	ENOG4105K59	histidine triad (HIT) protein
DA442_05080	ENOG4105D0Y	UPF0227 protein
DA442_05090	ENOG4105CEP	NADH dehydrogenase
DA442_05105	ENOG4108JA2	transcriptioN-repair coupling factor
DA442_05115	ENOG4105D60	lipoprotein releasing system transmembrane protein
DA442_05120	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DA442_05125	ENOG4105D60	lipoprotein releasing system transmembrane protein
DA442_05135	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
DA442_05140	ENOG4105BZ1	(ABC) transporter
DA442_05145	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
DA442_05150	ENOG4105W49	UPF0434 protein
DA442_05155	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
DA442_05160	ENOG4105ED1	spovr family
DA442_05165	ENOG4106AKX	UPF0229 protein
DA442_05170	ENOG4105CYN	Serine protein kinase
DA442_05180	ENOG4105XWI	UPF0304 protein
DA442_05190	ENOG4105F1A	Pyruvate formate-lyase
DA442_05200	ENOG4105C6N	Formate acetyltransferase
DA442_05220	ENOG4108JEH	abc transporter atp-binding protein
DA442_05225	ENOG4105E89	ABC transporter
DA442_05230	ENOG4105DSP	amino acid AbC transporter
DA442_05245	ENOG4105CGK	Exodeoxyribonuclease III
DA442_05250	ENOG4106428	Protein of unknown function (DUF2496)
DA442_05255	ENOG4108URS	primosomal replication protein n''
DA442_05260	ENOG4105EJ9	Membrane
DA442_05265	ENOG4105DVT	helicase
DA442_05280	ENOG4108R99	pseudouridine synthase
DA442_05290	ENOG4105VEQ	Cold shock protein
DA442_05295	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
DA442_05310	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
DA442_05315	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
DA442_05320	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
DA442_05335	ENOG4105RKX	Protein of unknown function (DUF2498)
DA442_05340	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
DA442_05345	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
DA442_05350	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
DA442_05370	ENOG4105HP8	regulator of competence-specific genes
DA442_05375	ENOG4105ETE	Transcriptional regulator (LacI family
DA442_05380	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
DA442_05385	ENOG4106WF9	DNA-binding transcriptional regulator TorR
DA442_05390	ENOG4107S90	membrAne
DA442_05395	ENOG4106371	Methyltransferase
DA442_05400	ENOG4105GHU	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity)
DA442_05405	ENOG4105DAH	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity)
DA442_05410	ENOG4105DUC	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division (By similarity)
DA442_05420	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
DA442_05430	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
DA442_05440	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
DA442_05445	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
DA442_05450	ENOG41081XQ	Conserved Protein
DA442_05455	ENOG4105C9M	aspartyl-trna synthetase
DA442_05460	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
DA442_05465	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_05470	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
DA442_05475	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
DA442_05480	ENOG4105C4M	(Ubiquinol oxidase) subunit I
DA442_05485	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
DA442_05500	ENOG4107YD3	Thioesterase
DA442_05505	ENOG4105E02	MotA TolQ exbB proton channel
DA442_05510	ENOG4105M8F	Biopolymer transport protein exbD tolR
DA442_05525	ENOG4105KCK	Peptidoglycan-associated lipoprotein
DA442_05530	ENOG4105UFD	tol-pal system protein YbgF
DA442_05535	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
DA442_05545	ENOG4105Z6B	inner membrane protein yjfl
DA442_05570	ENOG4108RNS	Exports L-alanine (By similarity)
DA442_05600	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_05615	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
DA442_05655	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
DA442_05665	ENOG4107R11	Transcriptional regulator
DA442_05680	ENOG4105EW9	transcriptional regulator AsnC family
DA442_05690	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
DA442_05700	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
DA442_05715	ENOG4105KSC	Transcriptional regulator, TraR DksA family
DA442_05720	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
DA442_05725	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
DA442_05730	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DA442_05740	ENOG4105EWW	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
DA442_05750	ENOG4105D0M	Protease HtpX homolog
DA442_05760	ENOG4107FW0	short-chain dehydrogenase reductase
DA442_05775	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
DA442_05800	ENOG4107QTF	adenylosuccinate lyase
DA442_05805	ENOG41075W9	High frequency lysogenization protein HflD homolog
DA442_05810	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
DA442_05820	ENOG4107RE1	Inosine-guanosine kinase
DA442_05825	ENOG4108YX2	DNA-binding protein
DA442_05830	ENOG4107S6Z	Na H antiporter
DA442_05840	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DA442_05845	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
DA442_05850	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
DA442_05855	ENOG4105CIH	Imidazole acetol-phosphate transaminase
DA442_05860	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
DA442_05865	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
DA442_05875	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
DA442_05880	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
DA442_05885	ENOG4105K5B	UPF0225 protein
DA442_05895	ENOG4105D58	Diguanylate phosphodiesterase
DA442_05900	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
DA442_05905	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
DA442_05910	ENOG4105C8N	cysteinyl-tRNA synthetase
DA442_05915	ENOG4107104	thymidine kinase
DA442_05920	ENOG4105GFG	DUF218 domain
DA442_05945	ENOG4105TMB	Formate nitrite transporter
DA442_05955	ENOG4105C4B	ABC transporter, permease
DA442_05970	ENOG4108J2R	molybdopterin oxidoreductase
DA442_05995	ENOG4108JQ2	peptide transport system atp-binding protein
DA442_06000	ENOG4108JQ3	Peptide ABC transporter ATP-binding protein
DA442_06005	ENOG4108EU3	peptide transport system, permease
DA442_06010	ENOG4108I5W	peptide transport system, permease protein
DA442_06015	ENOG4108J59	Extracellular solute-binding protein, family 5
DA442_06020	ENOG4105E51	psp operon transcriptional activator
DA442_06025	ENOG41087YS	Phage shock protein A
DA442_06030	ENOG4105YYT	phage shock protein B
DA442_06035	ENOG4105FM1	phage shock protein C
DA442_06055	ENOG4108R3E	Dna-3-methyladenine glycosylase i
DA442_06065	ENOG4107IFA	Lipase (EC 3.1.1.3)
DA442_06070	ENOG4105C28	cystathionine
DA442_06075	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
DA442_06080	ENOG4105C8J	)-transporter
DA442_06090	ENOG4108W1A	pseudouridine synthase
DA442_06100	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
DA442_06105	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
DA442_06110	ENOG4108JUA	Transcriptional regulator
DA442_06125	ENOG4108T9J	Cdp-alcohol phosphatidyltransferase
DA442_06130	ENOG4108VGW	abc transporter atp-binding protein
DA442_06135	ENOG4105CXZ	ABC transporter, permease
DA442_06140	ENOG4105VNH	ABC transporter solute-binding protein
DA442_06145	ENOG4108RSN	SNARE associated Golgi
DA442_06155	ENOG4105BZ8	glutamate synthase
DA442_06165	ENOG4106AFQ	Histidine kinase
DA442_06170	ENOG4108ZXC	Two component transcriptional regulator, luxr family
DA442_06180	ENOG4105XZD	Fe-S protein
DA442_06195	ENOG4105CGH	5'-nucleotidase
DA442_06210	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
DA442_06215	ENOG4105EB3	Histidine kinase
DA442_06220	ENOG4105ETX	regulatoR
DA442_06230	ENOG4105CFI	type iii restriction protein res subunit
DA442_06235	ENOG4105I08	Pseudouridine synthase
DA442_06240	ENOG4105C2C	drug resistance transporter, Bcr CflA
DA442_06270	ENOG4105CUW	cytochrome C-TYPE protein
DA442_06275	ENOG4105CGD	Nad-dependent epimerase dehydratase
DA442_06280	ENOG4107QI1	Mate efflux family protein
DA442_06285	ENOG4108I0Y	(ABC) transporter
DA442_06300	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
DA442_06305	ENOG41067SE	Tetr family transcriptional regulator
DA442_06315	ENOG4105RKW	reductase (By
DA442_06320	ENOG4105D0C	transport protein
DA442_06325	ENOG41090BQ	Glutaredoxin
DA442_06345	ENOG4105DY8	decarboxylase
DA442_06355	ENOG4105DWU	Membrane
DA442_06390	ENOG4105BZU	Histidine kinase
DA442_06400	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
DA442_06405	ENOG4105BZC	d-serine deaminase
DA442_06420	ENOG4105C3M	thioredoxin reductase
DA442_06440	ENOG4105BZU	Histidine kinase
DA442_06445	ENOG4105C8P	)-transporter
DA442_06450	ENOG4107GZ4	SanA protein
DA442_06455	ENOG4107R1I	NAD-dependent malic enzyme
DA442_06460	ENOG4105CQ7	ATP-dependent helicase
DA442_06465	ENOG4105HDD	phospholipase
DA442_06480	ENOG4105C8V	SAICAR synthetase
DA442_06500	ENOG4105CDV	Ompa motb domain protein
DA442_06515	ENOG4105CQB	FAD linked oxidase domain protein
DA442_06530	ENOG4105C84	Histidine ammonia-lyase
DA442_06545	ENOG4105CI2	imidazolone-5-propionate hydrolase
DA442_06550	ENOG4105CZE	histidine utilization repressor
DA442_06565	ENOG4105C22	threonyL-tRNA synthetase
DA442_06570	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
DA442_06575	ENOG41082NX	50s ribosomal protein l35
DA442_06580	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
DA442_06585	ENOG4105K8R	UPF0145 protein
DA442_06615	ENOG4105BZU	Histidine kinase
DA442_06625	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
DA442_06640	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
DA442_06650	ENOG4105FQ6	thiopurine methyltransferase
DA442_06655	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
DA442_06660	ENOG4107T42	This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis (By similarity)
DA442_06665	ENOG41067MG	lrgb family
DA442_06670	ENOG4105VAW	lrga family
DA442_06675	ENOG4105CJB	Exodeoxyribonuclease I
DA442_06680	ENOG4108ETY	sodium dicarboxylate symporter
DA442_06685	ENOG4105K4T	epimerase
DA442_06690	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
DA442_06695	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
DA442_06720	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
DA442_06725	ENOG4108IU2	vtamin B12-transporter permease
DA442_06730	ENOG41080WI	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity)
DA442_06750	ENOG4107RSM	transcriptional regulator
DA442_06770	ENOG4107XDJ	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
DA442_06780	ENOG4105KPE	licD family
DA442_06785	ENOG4108VKG	metal-dependent hydrolase
DA442_06790	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
DA442_06820	ENOG4105CTU	Proline racemase
DA442_06840	ENOG4105CIF	Ornithine Cyclodeaminase
DA442_06845	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
DA442_06850	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DA442_06855	ENOG4105F38	ABC transporter, permease
DA442_06860	ENOG4105D38	putrescine abc transporter
DA442_06875	ENOG4107MM9	BNR Asp-box repeat-containing protein
DA442_06890	ENOG4108JQ7	(ABC) transporter
DA442_06895	ENOG4105C3U	ABC transporter
DA442_06900	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DA442_06905	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DA442_06910	ENOG4107QSI	ABC, transporter
DA442_06915	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
DA442_06930	ENOG4105F1J	Homogentisate 1,2-dioxygenase
DA442_06940	ENOG4108RXX	maleylacetoacetate isomerase
DA442_07045	ENOG4105VEQ	Cold shock protein
DA442_07095	ENOG4108N0N	Phage Terminase Large Subunit
DA442_07320	ENOG4105DHJ	ABC, transporter
DA442_07365	ENOG4105D5Q	Arginine ornithine antiporter
DA442_07375	ENOG4105D5Q	Arginine ornithine antiporter
DA442_07385	ENOG4105CXN	decarboxylase
DA442_07390	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
DA442_07405	ENOG4105EQ2	LysR family Transcriptional regulator
DA442_07410	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DA442_07450	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DA442_07460	ENOG4105CPI	Metal Dependent Phosphohydrolase
DA442_07470	ENOG4105G0K	glycine radical enzyme YjjI family
DA442_07475	ENOG41076CZ	activating enzyme
DA442_07485	ENOG4105EE5	Membrane protein terC
DA442_07495	ENOG4105DR5	peptidase
DA442_07520	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DA442_07525	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DA442_07530	ENOG4108WC9	type VI secretion system effector, hcp1 family
DA442_07560	ENOG4105D9P	serine threonine protein kinase
DA442_07595	ENOG4105EW9	transcriptional regulator AsnC family
DA442_07680	ENOG4105DHT	Metal Dependent Phosphohydrolase
DA442_07695	ENOG4105E0U	tyrosine-specific transport protein
DA442_07725	ENOG4105BZ1	(ABC) transporter
DA442_07755	ENOG4105CFG	Acts as a chaperone (By similarity)
DA442_07760	ENOG4105CFG	Acts as a chaperone (By similarity)
DA442_07770	ENOG4105BZU	Histidine kinase
DA442_07800	ENOG4107QY8	reductase
DA442_07805	ENOG4105QAX	Iron-sulfur
DA442_07810	ENOG4107KGK	dmso reductase anchor subunit
DA442_07815	ENOG4108NEM	leader-binding protein dmsD
DA442_07825	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
DA442_07830	ENOG4105CQ7	ATP-dependent helicase
DA442_07845	ENOG4105C94	Transporter
DA442_07860	ENOG4105CND	Glycosyl transferase, family 2
DA442_07865	ENOG4105CPK	Glycosyl transferase (Group 1
DA442_07900	ENOG4107TYR	Glycosyl Transferase
DA442_07910	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DA442_07930	ENOG4107V1M	polysaccharide export protein
DA442_07940	ENOG41082AN	stage II sporulation protein
DA442_07955	ENOG4107QI1	Mate efflux family protein
DA442_07960	ENOG4108R6K	riboflavin synthase, subunit alpha
DA442_07970	ENOG4105FGM	Fructosamine kinase
DA442_07980	ENOG4105BZU	Histidine kinase
DA442_07990	ENOG4107TT5	NLP P60 protein
DA442_07995	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_08035	ENOG4105EZX	Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P (By similarity)
DA442_08045	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
DA442_08050	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
DA442_08055	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DA442_08075	ENOG4105BZU	Histidine kinase
DA442_08085	ENOG4105C5H	ABC transporter
DA442_08090	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
DA442_08115	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
DA442_08130	ENOG4105QAX	Iron-sulfur
DA442_08180	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
DA442_08185	ENOG4107RUE	extracellular solute-binding protein family 1
DA442_08190	ENOG4107RUE	extracellular solute-binding protein family 1
DA442_08195	ENOG4105D38	putrescine abc transporter
DA442_08200	ENOG4105F38	ABC transporter, permease
DA442_08205	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DA442_08225	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
DA442_08235	ENOG4105Q9Y	Universal stress protein
DA442_08240	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
DA442_08265	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
DA442_08295	ENOG4105BZU	Histidine kinase
DA442_08315	ENOG4108R9Q	Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain (By similarity)
DA442_08325	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
DA442_08340	ENOG4105C5H	ABC transporter
DA442_08350	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
DA442_08360	ENOG4108T7E	Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity)
DA442_08365	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
DA442_08370	ENOG4105C7I	Dehydrogenase
DA442_08380	ENOG4105CD8	aminopeptidase N
DA442_08390	ENOG4105CN1	protease
DA442_08395	ENOG41073DY	may be a structural element that influences the osmotic activation of ProP at a post-translational level (By similarity)
DA442_08400	ENOG4108ZGC	gaf domain protein
DA442_08405	ENOG4105BZ1	(ABC) transporter
DA442_08410	ENOG4105H2K	paraquat-inducible protein a
DA442_08415	ENOG4105DY2	Paraquat-inducible protein b
DA442_08425	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DA442_08445	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
DA442_08450	ENOG4108VPT	UPF0234 protein
DA442_08470	ENOG4107QXX	ABC transporter
DA442_08475	ENOG4105EZ7	amino acid ABC transporter
DA442_08480	ENOG4105DRP	amino acid AbC transporter
DA442_08485	ENOG4105CDA	abc transporter atp-binding protein
DA442_08490	ENOG4108MN8	Membrane
DA442_08500	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
DA442_08505	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
DA442_08510	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_08515	ENOG4105DR4	Methyltransferase
DA442_08530	ENOG4105CDV	Ompa motb domain protein
DA442_08560	ENOG4105CDV	Ompa motb domain protein
DA442_08570	ENOG4105BZU	Histidine kinase
DA442_08575	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
DA442_08580	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
DA442_08585	ENOG410667J	hydrolase
DA442_08605	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DA442_08610	ENOG4105C7F	AcnD-accessory protein PrpF
DA442_08615	ENOG4108I0Z	Aconitate hydratase
DA442_08620	ENOG4105BZN	citrate synthase
DA442_08765	ENOG41062JF	Transcriptional regulator
DA442_08850	ENOG41066XE	Type III export protein
DA442_08880	ENOG4108KB1	transcriptional regulator, arac family
DA442_08900	ENOG4105C26	Dehydrogenase
DA442_08905	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
DA442_08925	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
DA442_08930	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
DA442_08935	ENOG4108V9W	transcriptional regulatory protein
DA442_08940	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
DA442_08955	ENOG4107V40	secretion protein, HlyD family
DA442_08970	ENOG4105CA0	peroxidase
DA442_08975	ENOG4105CZK	Aspartate kinase
DA442_08980	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
DA442_08985	ENOG4108JPW	Aminotransferase
DA442_08990	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
DA442_08995	ENOG4105C94	Transporter
DA442_09010	ENOG4108IJ7	Glycine betaine
DA442_09015	ENOG4108HQS	Glycine betaine
DA442_09020	ENOG4105GIJ	Glycine betaine
DA442_09055	ENOG4105DHQ	Histidine kinase
DA442_09060	ENOG4105E0M	Sulfatase
DA442_09085	ENOG4105BZG	amino acid carrier protein
DA442_09095	ENOG410829K	Lysine exporter protein (Lyse ygga)
DA442_09100	ENOG4105CTD	carboxy-peptidase
DA442_09105	ENOG4105D1S	lipid A biosynthesis
DA442_09115	ENOG4105E5D	amino acid
DA442_09130	ENOG4105CVG	Homoserine O-transsuccinylase
DA442_09135	ENOG41090FY	type IV pilus biogenesis stability protein PilW
DA442_09165	ENOG4108UW5	maltose o-acetyltransferase
DA442_09185	ENOG4105MSB	protein, conserved in bacteria
DA442_09190	ENOG4108ZT1	Transcriptional regulator
DA442_09215	ENOG4105BZU	Histidine kinase
DA442_09225	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
DA442_09230	ENOG4108JPW	Aminotransferase
DA442_09240	ENOG4105DWY	Agmatine deiminase
DA442_09250	ENOG4105CJP	fad dependent oxidoreductase
DA442_09255	ENOG4105C26	Dehydrogenase
DA442_09260	ENOG4107VRI	Transcriptional regulator
DA442_09265	ENOG4108Z86	Glutamine amidotransferase
DA442_09275	ENOG4105CFQ	glutamine synthetase
DA442_09280	ENOG4107S6Z	Na H antiporter
DA442_09475	ENOG4108QDQ	Ubiquinol-cytochrome C chaperone 
DA442_09485	ENOG41067XF	inhibitor
DA442_09835	ENOG4108R4U	Hnh endonuclease
DA442_09860	ENOG4105D3W	isochorismatase
DA442_10075	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
DA442_10180	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
DA442_10215	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
DA442_10290	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
DA442_10510	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
DA442_10525	ENOG4105XYF	acetyltransferase
DA442_10595	ENOG4105D9U	N-acetyltransferase
DA442_10605	ENOG4106K28	UPF0283 membrane protein
DA442_10610	ENOG4105CM6	amino acid regulated cytosolic protein
DA442_10630	ENOG4105CRQ	synthase (Component I)
DA442_10635	ENOG4105BZU	Histidine kinase
DA442_10645	ENOG4105P8F	nudix hydrolase
DA442_10650	ENOG4105C44	Serine transporter
DA442_10655	ENOG4105EJQ	L-serine dehydratase
DA442_10660	ENOG4105BZU	Histidine kinase
DA442_10670	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
DA442_10675	ENOG4108N3W	hemolysin secretion protein
DA442_10680	ENOG4105C5S	asparaginyl-tRNA synthetase
DA442_10690	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DA442_10715	ENOG4105CGF	Aromatic amino acid aminotransferase
DA442_10735	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_10740	ENOG4105C94	Transporter
DA442_10745	ENOG41067TZ	transcriptional regulator, MarR family
DA442_10760	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
DA442_10770	ENOG4105CH5	extracellular solute-binding protein, family 7
DA442_10785	ENOG4105C5X	domain protein
DA442_10790	ENOG4105EAQ	(twin-arginine translocation) pathway signal
DA442_10795	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
DA442_10820	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
DA442_10830	ENOG4108DMF	Cytochrome C biogenesis protein
DA442_10835	ENOG4107QX9	Thiol disulfide interChange protein
DA442_10840	ENOG4105DA4	cytochrome c-type biogenesis protein
DA442_10845	ENOG4105DVI	reductase, NrfD
DA442_10850	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
DA442_10860	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
DA442_10875	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
DA442_10880	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DA442_10885	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DA442_10890	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
DA442_10915	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
DA442_10955	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
DA442_10960	ENOG4105WH1	Two component transcriptional regulator luxr family
DA442_10965	ENOG4105CQ2	DNA polymerase
DA442_10975	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
DA442_10980	ENOG4108W5H	UPF0263 protein
DA442_10990	ENOG4105FE9	pseudouridine synthase
DA442_11000	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
DA442_11005	ENOG4105DB7	PHP domain protein
DA442_11015	ENOG4105CRQ	synthase (Component I)
DA442_11020	ENOG4105DDQ	anthranilate synthase
DA442_11025	ENOG4108I0Q	anthranilate phosphoribosyltransferase
DA442_11030	ENOG4105DK0	Indole-3-glycerol phosphate synthase
DA442_11035	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DA442_11040	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
DA442_11050	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
DA442_11055	ENOG4105CEY	Amp-dependent synthetase and ligase
DA442_11065	ENOG4105CK2	sodium dicarboxylate symporter
DA442_11085	ENOG4107835	probably involved in intracellular septation (By similarity)
DA442_11090	ENOG4105NAU	thioesterase Superfamily protein
DA442_11095	ENOG4105K9H	YciI-like protein
DA442_11105	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
DA442_11115	ENOG4105DZ2	Transcriptional regulator
DA442_11135	ENOG4105CCT	upf0313 protein
DA442_11140	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_11150	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DA442_11155	ENOG41062D9	Histidine kinase
DA442_11175	ENOG4105JQN	Transcriptional regulator
DA442_11180	ENOG4105J12	Multidrug resistance protein mdtN
DA442_11190	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
DA442_11200	ENOG41063TF	transcriptional regulator (AraC
DA442_11205	ENOG4108W2Y	isochorismatase
DA442_11210	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DA442_11215	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DA442_11220	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DA442_11230	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
DA442_11245	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DA442_11260	ENOG4105N6Y	Thioredoxin
DA442_11265	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
DA442_11275	ENOG4105EXG	Transcriptional regulator
DA442_11280	ENOG4108ZXC	Two component transcriptional regulator, luxr family
DA442_11285	ENOG4106AFQ	Histidine kinase
DA442_11290	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
DA442_11295	ENOG4106WHD	Tetrathionate reductase
DA442_11300	ENOG4105DB1	molybdopterin oxidoreductase
DA442_11310	ENOG4105NQN	cytochrome C
DA442_11320	ENOG4105DY2	Paraquat-inducible protein b
DA442_11330	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
DA442_11340	ENOG4105CKK	Glycosyl transferase, family 2
DA442_11355	ENOG4108J59	Extracellular solute-binding protein, family 5
DA442_11360	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
DA442_11370	ENOG4105Q4A	inner membrane protein yciS
DA442_11375	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
DA442_11380	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
DA442_11385	ENOG4105CAT	Cytidine monophosphate kinase
DA442_11390	ENOG4105ERU	peptidase
DA442_11395	ENOG4105UBK	short-chain dehydrogenase reductase
DA442_11410	ENOG4105C0B	DNA polymerase III (alpha subunit)
DA442_11415	ENOG4107R88	Chemotaxis protein (CheV)
DA442_11420	ENOG4105DAG	ROK family
DA442_11425	ENOG4105CA9	Pyruvate kinase
DA442_11430	ENOG4108NRW	Phospholipase, patatin family
DA442_11445	ENOG4105C8J	)-transporter
DA442_11465	ENOG4105CI1	PTS System
DA442_11470	ENOG4105F8V	Hydrolase, tatD family
DA442_11475	ENOG4107QRG	dna polymerase iii
DA442_11480	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
DA442_11485	ENOG4105HHA	aminodeoxychorismate lyase
DA442_11495	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DA442_11500	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
DA442_11505	ENOG4105CHR	reductase
DA442_11510	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
DA442_11515	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DA442_11520	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
DA442_11525	ENOG4105VGS	50s ribosomal protein l32
DA442_11530	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
DA442_11535	ENOG4108UHJ	MAF-like protein
DA442_11540	ENOG4105EI2	Pseudouridine synthase
DA442_11555	ENOG4105C03	ribonuclease
DA442_11565	ENOG4105CHH	sulfate transporter
DA442_11575	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
DA442_11585	ENOG4105DBI	uridine monophosphokinase
DA442_11595	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
DA442_11605	ENOG4105C05	Multifunctional regulator of fatty acid metabolism (By similarity)
DA442_11610	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
DA442_11615	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
DA442_11620	ENOG4106RHG	Yeca family
DA442_11625	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
DA442_11630	ENOG4105BZU	Histidine kinase
DA442_11635	ENOG4107R28	alpha amylase, catalytic region
DA442_11640	ENOG4108JJB	ABC transporter
DA442_11655	ENOG4105PQ6	UPF0208 membrane protein
DA442_11660	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
DA442_11665	ENOG4108DNC	Involved in acetate metabolism (By similarity)
DA442_11670	ENOG4107PU6	Membrane
DA442_11680	ENOG4105CHF	Glutathione S-transferase
DA442_11685	ENOG4108JQ7	(ABC) transporter
DA442_11690	ENOG4105C3U	ABC transporter
DA442_11695	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DA442_11700	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
DA442_11705	ENOG4107QSI	ABC, transporter
DA442_11710	ENOG4108ZAF	Molybdopterin
DA442_11715	ENOG4105M00	molybdopterin converting factor, subunit 1
DA442_11720	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DA442_11725	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
DA442_11730	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
DA442_11735	ENOG4105CHW	UPF0052 protein
DA442_11750	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
DA442_11765	ENOG4105DGN	Electron transport complex
DA442_11770	ENOG4108R3D	Electron transport complex
DA442_11780	ENOG4105D6A	Electron transport complex
DA442_11785	ENOG4108UQQ	Electron transport complex
DA442_11790	ENOG4105DZB	Electron transport complex
DA442_11795	ENOG4105CSM	endonuclease III
DA442_11800	ENOG4108UYE	Lactoylglutathione lyase
DA442_11805	ENOG4106WH9	Protein of unknown function (DUF2753)
DA442_11810	ENOG4105EIY	sodium-type flagellar protein motY
DA442_11825	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
DA442_11830	ENOG4105D3Y	Na H antiporter
DA442_11840	ENOG4105M2J	Glutaredoxin
DA442_11845	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
DA442_11860	ENOG4108EKI	Dehydrogenase
DA442_11865	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
DA442_11870	ENOG4105EYW	Ion transport protein
DA442_11875	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
DA442_11880	ENOG4105DFD	Na H antiporter
DA442_11895	ENOG4106V8H	Nucleoid-associated protein
DA442_11900	ENOG4105YDX	UPF0352 protein
DA442_11905	ENOG4105E68	Sulfatase
DA442_11915	ENOG4105DGU	Histone deacetylase
DA442_11920	ENOG4108RU0	short-chain dehydrogenase reductase
DA442_11935	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
DA442_11940	ENOG41069NU	Nitroreductase
DA442_11945	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DA442_11955	ENOG4105HDK	L-asparaginase
DA442_11960	ENOG4105VUT	cytoplasmic protein
DA442_11970	ENOG4105E0X	reductase
DA442_11975	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DA442_11980	ENOG4105DSB	aldose 1-epimerase
DA442_11985	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_11990	ENOG4105DHI	Methyltransferase
DA442_12010	ENOG4105G6Z	alkaline phosphatase
DA442_12020	ENOG4108UYE	Lactoylglutathione lyase
DA442_12025	ENOG41067V3	Antibiotic biosynthesis monooxygenase
DA442_12035	ENOG4108ZZ3	UPF0260 protein
DA442_12040	ENOG4105Y3U	Transglycosylase-associated protein
DA442_12045	ENOG4105KRS	Proteinase inhibitor
DA442_12055	ENOG4105CEM	UPF0597 protein
DA442_12060	ENOG4105KME	endoribonuclease L-psp
DA442_12065	ENOG4105C44	Serine transporter
DA442_12070	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
DA442_12075	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
DA442_12080	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
DA442_12085	ENOG4107QMP	dna polymerase iii subunits gamma and tau
DA442_12090	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
DA442_12095	ENOG4105WD1	Membrane
DA442_12105	ENOG4105I93	response regulator
DA442_12110	ENOG4105EJC	lysr family transcriptional regulator
DA442_12115	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
DA442_12120	ENOG4105E96	Colicin v production protein
DA442_12125	ENOG4108S3P	Sporulation domain protein
DA442_12130	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
DA442_12135	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
DA442_12140	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
DA442_12150	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
DA442_12155	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
DA442_12165	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
DA442_12170	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
DA442_12185	ENOG4105MH2	YfcL protein
DA442_12190	ENOG4108BPE	-transporting atpase
DA442_12200	ENOG4105EN6	Membrane
DA442_12205	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
DA442_12210	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
DA442_12220	ENOG4108BY2	phosphohistidine phosphatase
DA442_12235	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
DA442_12240	ENOG4105CHU	acetyl-coa acetyltransferase
DA442_12260	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
DA442_12265	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
DA442_12270	ENOG410903C	(LipO)protein
DA442_12280	ENOG4108M1T	Cytochrome c-type biogenesis protein
DA442_12285	ENOG4107QX9	Thiol disulfide interChange protein
DA442_12290	ENOG4105DA4	cytochrome c-type biogenesis protein
DA442_12300	ENOG4105X3C	heme exporter protein
DA442_12305	ENOG41060IM	Heme exporter protein
DA442_12310	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
DA442_12315	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
DA442_12325	ENOG4108V3W	Chemotaxis protein, CheW
DA442_12335	ENOG4107QJE	Chromosome Partitioning Protein
DA442_12340	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
DA442_12345	ENOG4105CBS	Chea signal transduction histidine kinase
DA442_12350	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
DA442_12355	ENOG4108VYJ	response regulator receiver protein
DA442_12360	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DA442_12365	ENOG4107R21	site-determining protein
DA442_12370	ENOG4105FZW	flagellar biosynthesis regulator FlhF
DA442_12375	ENOG4105D7B	Flagellar biosynthesis protein flha
DA442_12380	ENOG4105D00	flagellar biosynthetic protein flhB
DA442_12385	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
DA442_12390	ENOG4105VS8	Flagellar biosynthetic protein fliq
DA442_12395	ENOG4105CN7	Flagellar biosynthetic protein FliP
DA442_12400	ENOG4105VTB	flagellar biosynthesis protein fliO
DA442_12405	ENOG4105DD5	Flagellar motor switch protein
DA442_12410	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
DA442_12430	ENOG4108JIR	Flagellum-specific ATP synthase
DA442_12440	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
DA442_12445	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
DA442_12450	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
DA442_12455	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DA442_12460	ENOG4105BZU	Histidine kinase
DA442_12465	ENOG4108JUA	Transcriptional regulator
DA442_12470	ENOG4105MQ3	flagellar protein FliS
DA442_12480	ENOG4107BRV	flagellar capping protein
DA442_12485	ENOG41063QE	flagellar protein FlaG
DA442_12495	ENOG4105I03	Flagellin
DA442_12505	ENOG4105I03	Flagellin
DA442_12510	ENOG4105EZR	dyp-type peroxidase family protein
DA442_12515	ENOG4105QZU	Inner membrane protein YfeZ
DA442_12540	ENOG4105KUZ	arsenate reductase
DA442_12545	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DA442_12560	ENOG4107EG0	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
DA442_12570	ENOG4105RH4	Glycine cleavage system transcriptional repressor
DA442_12575	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DA442_12590	ENOG4105ERG	peptidase m48, ste24p
DA442_12595	ENOG4105K89	arsenate reductase
DA442_12600	ENOG4105CS1	NAD(P)H quinone oxidoreductase
DA442_12615	ENOG4105C2W	permease
DA442_12620	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
DA442_12625	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
DA442_12630	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
DA442_12635	ENOG4105E7A	Glutamine amidotransferase
DA442_12640	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
DA442_12645	ENOG4107QPN	acyl-Coa dehydrogenase
DA442_12675	ENOG4107RZZ	dna polymerase iii epsilon subunit
DA442_12680	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
DA442_12685	ENOG4105D1A	Methyltransferase
DA442_12690	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
DA442_12695	ENOG4105E9H	Lytic Murein transglycosylase
DA442_12705	ENOG4107NA1	Endonuclease Exonuclease phosphatase
DA442_12710	ENOG4108YZA	Nitrogen regulatory protein pii
DA442_12720	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
DA442_12725	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
DA442_12730	ENOG4105C0B	DNA polymerase III (alpha subunit)
DA442_12740	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DA442_12745	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
DA442_12750	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
DA442_12755	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
DA442_12765	ENOG4105DZP	Membrane-associated zinc metalloprotease
DA442_12770	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
DA442_12775	ENOG4105KNE	Phosphatidate cytidylyltransferase
DA442_12780	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
DA442_12785	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
DA442_12790	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
DA442_12795	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
DA442_12800	ENOG4105CE9	30S ribosomal protein S2
DA442_12805	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
DA442_12810	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
DA442_12815	ENOG4108T8E	UPF0325 protein
DA442_12820	ENOG4105DR9	pseudouridine synthase
DA442_12825	ENOG4105WP7	tRNA pseudouridine synthase C
DA442_12850	ENOG4108UPT	UPF0178 protein
DA442_12855	ENOG4105CFC	Transporter
DA442_12865	ENOG4105NRA	50s ribosomal protein l31 type b
DA442_12870	ENOG4108R96	Methyltransferase, YaeB family
DA442_12875	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
DA442_12885	ENOG4105W1I	UPF0253 protein
DA442_12895	ENOG4105C8J	)-transporter
DA442_12910	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
DA442_12915	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DA442_12920	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
DA442_12935	ENOG4105CJ2	(LipO)protein
DA442_12940	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
DA442_12945	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
DA442_12950	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
DA442_12955	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
DA442_12960	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
DA442_12965	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
DA442_12975	ENOG4105M85	Bola protein
DA442_12980	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
DA442_12985	ENOG4105IEY	(LipO)protein
DA442_12990	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
DA442_13005	ENOG4105K6V	RNA polymerase
DA442_13030	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
DA442_13035	ENOG4107S0N	DJ-1 family
DA442_13040	ENOG4105C9B	Cysteine desulfurase
DA442_13045	ENOG4105BZU	Histidine kinase
DA442_13050	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
DA442_13055	ENOG4105CUZ	uba thif-type nad fad binding protein
DA442_13060	ENOG4105CA3	membrane-bound lytic murein transglycosylase
DA442_13075	ENOG4107QZM	n-acetylglutamate synthase
DA442_13100	ENOG4107QYX	exodeoxyribonuclease v alpha
DA442_13105	ENOG4107QKA	exodeoxyribonuclease V beta
DA442_13115	ENOG4105DSY	exodeoxyribonuclease V, gamma
DA442_13120	ENOG4105E68	Sulfatase
DA442_13130	ENOG4105EVZ	LysR family transcriptional regulator
DA442_13135	ENOG4105X2V	dna damage-inducible protein
DA442_13140	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
DA442_13145	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
DA442_13150	ENOG4105CXY	transporter
DA442_13165	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
DA442_13170	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
DA442_13175	ENOG4105E98	transcriptional regulator DeoR family
DA442_13180	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
DA442_13185	ENOG4107RX3	Mg2 transporter protein cora family protein
DA442_13200	ENOG4108Y51	tRNA-binding protein
DA442_13205	ENOG41060NJ	transcriptional regulator
DA442_13210	ENOG4105CT4	transporter
DA442_13220	ENOG4105ETE	Transcriptional regulator (LacI family
DA442_13225	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
DA442_13230	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
DA442_13235	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
DA442_13240	ENOG4105CMR	udp-glucose 4-epimerase
DA442_13250	ENOG4105CQ4	Transcriptional regulator
DA442_13255	ENOG4105CNT	hydrolase family 2
DA442_13260	ENOG4105FK9	beta-D-galactosidase beta subunit
DA442_13265	ENOG4105E5D	amino acid
DA442_13270	ENOG41064T2	transcriptional regulator, lysR family
DA442_13360	ENOG4108IQE	Amp-dependent synthetase and ligase
DA442_13370	ENOG4105ETT	transcriptional Regulator, LysR family
DA442_13375	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DA442_13380	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
DA442_13390	ENOG4105EAC	phosphoserine phosphatase
DA442_13400	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DA442_13405	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
DA442_13410	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
DA442_13415	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
DA442_13420	ENOG4105D9N	nucleoside
DA442_13425	ENOG4105EYA	deoxyribonuclease
DA442_13435	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
DA442_13525	ENOG4108YGG	dna repair protein
DA442_13550	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
DA442_13565	ENOG4108UUM	single-stranded DNA-binding protein
DA442_13620	ENOG4105T95	Thiol disulfide interChange protein
DA442_13705	ENOG4105ESI	atpase involved in dna repair
DA442_13770	ENOG4105KT5	UmuD protein
DA442_13815	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
DA442_13835	ENOG4108YYD	acetyltransferase
DA442_13840	ENOG4105XPQ	lipid carrier protein
DA442_13845	ENOG4105BZU	Histidine kinase
DA442_13850	ENOG4105CFP	Peptidase U32
DA442_13855	ENOG4106RZ4	Peptidase U32
DA442_13860	ENOG4105C3S	Mate efflux family protein
DA442_13875	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
DA442_13880	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
DA442_13885	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
DA442_13890	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
DA442_13895	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
DA442_13900	ENOG4105CHV	Transcription elongation factor NusA
DA442_13905	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
DA442_13930	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
DA442_13935	ENOG4105EEI	dihydropteroate synthase
DA442_13940	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
DA442_13945	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
DA442_13950	ENOG4105HBR	Rna-binding protein
DA442_13955	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
DA442_13960	ENOG4107QE9	Inherit from COG: Membrane
DA442_13965	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
DA442_13975	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DA442_13980	ENOG4105DR5	peptidase
DA442_13995	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
DA442_14000	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
DA442_14010	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
DA442_14020	ENOG4105BZU	Histidine kinase
DA442_14025	ENOG4107QRA	Extracellular solute-binding protein, family 5
DA442_14035	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
DA442_14040	ENOG4105C3U	ABC transporter
DA442_14045	ENOG4108JQ7	(ABC) transporter
DA442_14055	ENOG4105RD7	BadF BadG BcrA BcrD
DA442_14060	ENOG4105E2D	ec 3.2.1.52
DA442_14070	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
DA442_14075	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DA442_14095	ENOG4108YZA	Nitrogen regulatory protein pii
DA442_14100	ENOG4105XTV	UPF0231 protein
DA442_14110	ENOG4105D78	K07001 NTE family protein
DA442_14115	ENOG4105BZ4	penicillin-binding protein
DA442_14120	ENOG4105CQ7	ATP-dependent helicase
DA442_14125	ENOG4105PW4	Sugar fermentation stimulation protein homolog
DA442_14130	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DA442_14140	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
DA442_14150	ENOG4105DJ0	Poly(A) Polymerase
DA442_14155	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DA442_14160	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
DA442_14165	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
DA442_14175	ENOG4105D1S	lipid A biosynthesis
DA442_14185	ENOG4105E3A	(ABC) transporter
DA442_14190	ENOG4105DA5	(ABC) transporter
DA442_14200	ENOG4105CHH	sulfate transporter
DA442_14205	ENOG41077A9	carbonic anhydrase
DA442_14210	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
DA442_14215	ENOG410630P	Transcriptional regulator
DA442_14220	ENOG4107QN2	dihydrolipoyl dehydrogenase
DA442_14225	ENOG4107QSN	dihydrolipoamide acetyltransferase
DA442_14230	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
DA442_14235	ENOG41073TP	transcriptional regulator
DA442_14245	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
DA442_14255	ENOG4107QHF	type ii secretion system protein e
DA442_14260	ENOG4105D7Q	type ii secretion system
DA442_14265	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
DA442_14270	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
DA442_14275	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
DA442_14280	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
DA442_14285	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
DA442_14290	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
DA442_14295	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
DA442_14300	ENOG4105K5M	30s ribosomal protein S16
DA442_14305	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DA442_14310	ENOG4106KVJ	cytochrome C assembly protein
DA442_14315	ENOG4108JU6	CBS domain protein
DA442_14320	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
DA442_14330	ENOG4105D9M	gamma-glutamylcysteine synthetase
DA442_14340	ENOG4105W39	Membrane
DA442_14345	ENOG4105CPQ	Dehydrogenase
DA442_14350	ENOG4105D9Q	decarboxylase (Beta subunit)
DA442_14355	ENOG4107QSA	Oxaloacetate decarboxylase
DA442_14360	ENOG4106AFN	Lyase and sodium transporter (By similarity)
DA442_14415	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
DA442_14420	ENOG4105CFH	Aspartokinase
DA442_14425	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
DA442_14430	ENOG4105Y3E	Modulates RecA activity (By similarity)
DA442_14440	ENOG4107TH8	cina domain protein
DA442_14445	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
DA442_14460	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
DA442_14465	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
DA442_14470	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
DA442_14475	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
DA442_14480	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
DA442_14485	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
DA442_14490	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
DA442_14495	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
DA442_14500	ENOG4105DXN	mazG family
DA442_14505	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
DA442_14515	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
DA442_14525	ENOG4105BZU	Histidine kinase
DA442_14530	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
DA442_14535	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
DA442_14540	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
DA442_14545	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
DA442_14550	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
DA442_14555	ENOG4105C3F	Signal peptidase i
DA442_14560	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
DA442_14575	ENOG41069PW	sigma-e factor negative regulatory protein
DA442_14580	ENOG4105EMN	RNA polymerase sigma factor
DA442_14590	ENOG4108IYU	L-aspartate oxidase
DA442_14600	ENOG4105Y75	tpr repeat protein
DA442_14605	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
DA442_14620	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
DA442_14625	ENOG4105D0A	hydroxylase
DA442_14640	ENOG4107YUN	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
DA442_14650	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
DA442_14655	ENOG4105E66	phosphoriboisomerase A
DA442_14660	ENOG4108JQ1	Dehydrogenase
DA442_14665	ENOG4105MPN	Membrane
DA442_14670	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
DA442_14680	ENOG4108KXH	Ybak prolyl-tRNA synthetase associated
DA442_14685	ENOG4105D64	Mechanosensitive ion channel
DA442_14690	ENOG4105D2N	Aldolase
DA442_14695	ENOG4105BZA	Phosphoglycerate kinase
DA442_14700	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DA442_14705	ENOG4105D05	Receptor
DA442_14710	ENOG4108R4R	Iron-regulated virulence regulatory protein
DA442_14715	ENOG4105CV1	Transketolase (EC 2.2.1.1)
DA442_14725	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
DA442_14735	ENOG4105GPY	SprT protein
DA442_14740	ENOG4105RWS	endonuclease I
DA442_14745	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
DA442_14750	ENOG4105D7Z	glutathione synthase
DA442_14755	ENOG4108UJU	UPF0301 protein
DA442_14760	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
DA442_14765	ENOG4105CZX	twitching motility protein
DA442_14770	ENOG4105CZX	twitching motility protein
DA442_14775	ENOG4105DFA	alanine racemase domain protein
DA442_14780	ENOG4105II7	pyrroline-5-carboxylate reductase
DA442_14785	ENOG4108VIA	integral membrane protein
DA442_14800	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
DA442_14805	ENOG4105CSA	Coproporphyrinogen iii oxidase
DA442_14810	ENOG4105CSV	Glutaminase
DA442_14820	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
DA442_14825	ENOG4105CEN	a g-specific adenine glycosylase
DA442_14830	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
DA442_14835	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
DA442_14875	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_14905	ENOG4105C26	Dehydrogenase
DA442_14955	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
DA442_14965	ENOG410901P	UPF0249 protein
DA442_14970	ENOG4105F8D	glycoside hydrolase family 4
DA442_14975	ENOG4105VCP	PTS System
DA442_14980	ENOG4105CK1	PTS System
DA442_15005	ENOG4107JEE	Short-chain dehydrogenase reductase Sdr
DA442_15010	ENOG4105EXU	Membrane
DA442_15020	ENOG4108K5H	permease YjgP YjgQ family protein
DA442_15025	ENOG4108M8S	permease YjgP YjgQ family protein
DA442_15030	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
DA442_15035	ENOG4105MYG	DNA polymerase iii, chi subunit
DA442_15040	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
DA442_15050	ENOG4108MJ3	acetyltransferase
DA442_15070	ENOG4105CEU	Arginine dihydrolase
DA442_15075	ENOG4105DBV	ornithine carbamoyltransferase
DA442_15085	ENOG4105CXT	aspartate transcarbamylase
DA442_15090	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
DA442_15095	ENOG4105KME	endoribonuclease L-psp
DA442_15100	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
DA442_15105	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
DA442_15110	ENOG4105VFK	BolA family
DA442_15120	ENOG4105E3I	toluene tolerance
DA442_15125	ENOG4107PE3	Mammalian cell entry related domain protein
DA442_15130	ENOG4105CY3	ABC transporter, permease
DA442_15135	ENOG4105DHJ	ABC, transporter
DA442_15145	ENOG4105C2X	Arabinose 5-phosphate isomerase
DA442_15155	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
DA442_15160	ENOG4108IUZ	ABC transporter
DA442_15165	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DA442_15170	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
DA442_15175	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
DA442_15180	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
DA442_15185	ENOG41080Z8	PHOSPHOCARRIER protein
DA442_15190	ENOG4105CJW	magnesium transporter
DA442_15195	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
DA442_15200	ENOG4105N42	UPF0307 protein
DA442_15205	ENOG4105C5I	Dehydrogenase
DA442_15210	ENOG4105D3G	Pseudouridine synthase
DA442_15220	ENOG4105K3M	)-transporter
DA442_15225	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
DA442_15230	ENOG4108IAB	Phoh family
DA442_15235	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
DA442_15245	ENOG4105QD6	exported protein
DA442_15250	ENOG4105C03	ribonuclease
DA442_15255	ENOG4108Z03	MAF-like protein
DA442_15260	ENOG4105VQ7	Rod shape-determining protein MreD
DA442_15265	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
DA442_15270	ENOG4105DFF	Rod shape-determining protein mreb
DA442_15315	ENOG4105D7Q	type ii secretion system
DA442_15320	ENOG4107QHF	type ii secretion system protein e
DA442_15335	ENOG4105E4G	Type IV pilus
DA442_15355	ENOG41062P1	Diguanylate cyclase phosphodiesterase
DA442_15360	ENOG4108UUM	single-stranded DNA-binding protein
DA442_15365	ENOG41086KC	Transcriptional regulator
DA442_15370	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
DA442_15375	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
DA442_15385	ENOG4105C5R	Aminotransferase
DA442_15400	ENOG4105C3R	Methionine synthase
DA442_15405	ENOG4105EEQ	Na H antiporter
DA442_15480	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
DA442_15485	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
DA442_15490	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
DA442_15515	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
DA442_15525	ENOG4105MYN	Zinc uptake regulation protein
DA442_15535	ENOG4107QP8	phosphohexose isomerase
DA442_15540	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
DA442_15550	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DA442_15555	ENOG4105CDU	Replicative dna helicase
DA442_15565	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
DA442_15570	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
DA442_15575	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
DA442_15580	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
DA442_15585	ENOG4105DJV	ribulose-phosphate 3-epimerase
DA442_15590	ENOG4105DFE	Dna adenine methylase
DA442_15600	ENOG4105D49	3-dehydroquinate synthase
DA442_15605	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
DA442_15610	ENOG4105E4G	Type IV pilus
DA442_15635	ENOG4108JQC	penicillin-binding protein 1A
DA442_15645	ENOG4105EHV	domain protein
DA442_15660	ENOG4105CH7	arginosuccinase
DA442_15665	ENOG4105CDH	Citrulline--aspartate ligase
DA442_15670	ENOG4105CAS	nag kinase
DA442_15675	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
DA442_15680	ENOG4105CWC	Acetylornithine deacetylase
DA442_15685	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
DA442_15695	ENOG4105SYT	Methylenetetrahydrofolate reductase
DA442_15700	ENOG4105CFH	Aspartokinase
DA442_15705	ENOG4105C28	cystathionine
DA442_15715	ENOG4105C6K	Malic enzyme
DA442_15720	ENOG4108UQY	Iron-storage protein
DA442_15725	ENOG4105W53	bacterioferritin-associated ferredoxin
DA442_15730	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DA442_15735	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DA442_15740	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
DA442_15745	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
DA442_15750	ENOG4105YKK	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
DA442_15755	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
DA442_15760	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
DA442_15765	ENOG4105WWK	YheO domain protein
DA442_15770	ENOG4108V1T	peptidylprolyl cis-trans isomerase
DA442_15780	ENOG41069P5	Protein slyX homolog
DA442_15785	ENOG4105D44	asparaginase
DA442_15795	ENOG4108YZY	peptidylprolyl cis-trans isomerase
DA442_15810	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
DA442_15820	ENOG4105C5H	ABC transporter
DA442_15830	ENOG4105DNZ	Alpha Beta Hydrolase
DA442_15840	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
DA442_15845	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
DA442_15855	ENOG4105C26	Dehydrogenase
DA442_15865	ENOG4105C8Y	Acetylornithine aminotransferase
DA442_15870	ENOG4105DDQ	anthranilate synthase
DA442_15900	ENOG4105C31	Tryptophanyl-tRNA synthetase
DA442_15905	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
DA442_15910	ENOG4105C2N	RNA methyltransferase TrmH family group 3
DA442_15915	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
DA442_15920	ENOG4105KPV	Transcriptional regulator
DA442_15925	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
DA442_15930	ENOG4108UV7	flagellar protein motX
DA442_15940	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
DA442_15950	ENOG4105EPW	hflc protein
DA442_15955	ENOG4107QJR	hflk protein
DA442_15960	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
DA442_15965	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
DA442_15970	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
DA442_15975	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
DA442_15980	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
DA442_15985	ENOG4105K8N	protein family UPF0079, ATPase
DA442_15990	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
DA442_16060	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
DA442_16065	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DA442_16070	ENOG4105DJ4	phosphatidylserine decarboxylase
DA442_16075	ENOG4105C8P	)-transporter
DA442_16080	ENOG4108NVR	Methyl-accepting chemotaxis
DA442_16090	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
DA442_16095	ENOG4107YZP	Rhodanese domain protein
DA442_16100	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
DA442_16105	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
DA442_16110	ENOG4105D7W	serine acetyltransferase
DA442_16115	ENOG41063SB	peptidase
DA442_16125	ENOG41062JF	Transcriptional regulator
DA442_16135	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
DA442_16150	ENOG4105E33	succinate dehydrogenase
DA442_16155	ENOG4108WJH	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
DA442_16160	ENOG4108VP9	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity)
DA442_16170	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
DA442_16175	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
DA442_16185	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DA442_16205	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DA442_16215	ENOG4107QI1	Mate efflux family protein
DA442_16220	ENOG4105CTQ	phosphohexokinase
DA442_16225	ENOG41076HS	cation diffusion facilitator family transporter
DA442_16230	ENOG4108SPG	Periplasmic Protein
DA442_16240	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
DA442_16245	ENOG4105E0F	Histidine kinase
DA442_16255	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
DA442_16260	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
DA442_16265	ENOG4108IJ0	Aspartate ammonia-lyase
DA442_16270	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
DA442_16275	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
DA442_16285	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
DA442_16295	ENOG4107QN1	sodium solute
DA442_16315	ENOG4105C9Q	fumarate hydratase class II
DA442_16320	ENOG4105BZU	Histidine kinase
DA442_16325	ENOG4105D8G	Major Facilitator superfamily
DA442_16340	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DA442_16345	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
DA442_16350	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
DA442_16355	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
DA442_16365	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
DA442_16370	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
DA442_16375	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
DA442_16385	ENOG4105C5H	ABC transporter
DA442_16390	ENOG4105BZU	Histidine kinase
DA442_16465	ENOG4105CXN	decarboxylase
DA442_16470	ENOG4105D5Q	Arginine ornithine antiporter
DA442_16480	ENOG4108M3R	transcriptional activator CadC
DA442_16485	ENOG4105W1Y	Transcriptional regulator
DA442_16495	ENOG4105DC1	bifunctional purine biosynthesis protein purh
DA442_16505	ENOG4105C12	Phosphoribosylglycinamide synthetase
DA442_16525	ENOG4105R2J	Conserved Protein
DA442_16530	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
DA442_16535	ENOG4108RG0	uracil-dna glycosylase
DA442_16540	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
DA442_16555	ENOG4105E09	nadh pyrophosphatase
DA442_16560	ENOG4108ZVW	Anti-RNA polymerase sigma 70 factor
DA442_16565	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DA442_16570	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
DA442_16575	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
DA442_16580	ENOG4108VZM	50s ribosomal protein L10
DA442_16585	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
DA442_16590	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
DA442_16595	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
DA442_16600	ENOG4105PM1	preprotein translocase subunit SecE
DA442_16610	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
DA442_16635	ENOG4105CS9	pantothenic acid kinase
DA442_16640	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
DA442_16645	ENOG4105D4A	Cell wall formation (By similarity)
DA442_16655	ENOG4105JIM	Phosphatidylserine synthase
DA442_16715	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
DA442_16725	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
DA442_16730	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
DA442_16745	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
DA442_16750	ENOG4107R73	Mate efflux family protein
DA442_16760	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
DA442_16770	ENOG4105E55	glycerol-3-phosphate acyltransferase
DA442_16775	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
DA442_16780	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
DA442_16785	ENOG4105X6C	Flagellar basal body-associated protein FliL
DA442_16790	ENOG4105EBW	Rhomboid-type serine protease that catalyzes intramembrane proteolysis (By similarity)
DA442_16795	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
DA442_16805	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
DA442_16810	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
DA442_16815	ENOG4105CAK	Cell division ATP-binding protein ftsE
DA442_16820	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DA442_16825	ENOG4106H78	methyltransferase
DA442_16835	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
DA442_16890	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
DA442_16895	ENOG41082YX	Transcriptional regulator, arsr family
DA442_16900	ENOG4105D58	Diguanylate phosphodiesterase
DA442_16905	ENOG410829K	Lysine exporter protein (Lyse ygga)
DA442_16910	ENOG4108EUD	Lysophospholipase
DA442_16920	ENOG4105DQF	Hydrolase
DA442_16935	ENOG4106IUH	DTW domain containing protein
DA442_16940	ENOG4105BZU	Histidine kinase
DA442_16945	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
DA442_16950	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DA442_16960	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
DA442_16965	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DA442_16975	ENOG4105XQ6	frataxin-like protein
DA442_16980	ENOG4107T0K	Adenylate cyclase
DA442_16985	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
DA442_16990	ENOG41076E6	Uroporphyrinogen-III Synthase
DA442_16995	ENOG4105ECF	c-methyltransferase
DA442_17000	ENOG410601J	HemY protein
DA442_17050	ENOG4107QK7	reductase
DA442_17055	ENOG4108ZIT	Ferredoxin, 2FE-2S
DA442_17060	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
DA442_17075	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
DA442_17080	ENOG4105K63	Thioredoxin
DA442_17085	ENOG4105C1J	atp-dependent rna helicase
DA442_17090	ENOG4105C9X	ppx gppa phosphatase
DA442_17095	ENOG4105EX9	Membrane
DA442_17110	ENOG4105C9U	ATP-dependent DNA helicase RecQ
DA442_17115	ENOG4105FR1	rard protein
DA442_17130	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
DA442_17140	ENOG4105C4R	Atp-dependent dna helicase
DA442_17150	ENOG4105E18	UPF0276 protein
DA442_17180	ENOG4105DC7	peptidase M24
DA442_17180	ENOG4105DC7	peptidase M24
DA442_17185	ENOG4105D41	biosynthesis protein thiH
DA442_17190	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
DA442_17195	ENOG4105WHD	thiamine biosynthesis protein ThiS
DA442_17200	ENOG4105D06	uba thif-type nad fad binding protein
DA442_17205	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
DA442_17210	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
DA442_17215	ENOG4105WMR	Protein CrcB homolog
DA442_17270	ENOG4108Z0R	Transferase
DA442_17275	ENOG4105SG3	Protein of unknown function (DUF1488)
DA442_17280	ENOG4105E2X	shikimate dehydrogenase
DA442_17285	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
DA442_17290	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
DA442_17295	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
DA442_17300	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
DA442_17305	ENOG4108WI1	Dna topoisomerase
DA442_17310	ENOG4108RPN	Protein smg homolog
DA442_17315	ENOG4105C79	DNA protecting protein DprA
DA442_17325	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DA442_17330	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
DA442_17335	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
DA442_17340	ENOG4105C1A	potassium transporter peripheral membrane
DA442_17345	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
DA442_17355	ENOG4108UT2	hemolysin iii
DA442_17360	ENOG4108N23	SpoOM-related protein
DA442_17370	ENOG4105PC1	Conserved Protein
DA442_17380	ENOG4105E27	serine threonine protein kinase
DA442_17385	ENOG4108Z33	Thiol disulfide Interchange Protein
DA442_17390	ENOG4106HNH	Acyl-transferase
DA442_17400	ENOG4105C0P	Mg chelatase subunit ChlI
DA442_17410	ENOG4105P3Y	Acetolactate synthase 2 regulatory subunit
DA442_17415	ENOG4105CM2	brancheD-chain amino acid aminotransferase
DA442_17420	ENOG4105C01	Dihydroxy-acid dehydratase
DA442_17425	ENOG4105C7B	Threonine dehydratase
DA442_17430	ENOG4105F52	Transcriptional regulator
DA442_17435	ENOG4105CZQ	inner membrane transport protein YdhC
DA442_17445	ENOG4105EAD	ABC transporter
DA442_17450	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
DA442_17455	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
DA442_17460	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
DA442_17465	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
DA442_17470	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
DA442_17475	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DA442_17480	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DA442_17485	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
DA442_17490	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
DA442_17495	ENOG410684E	atp synthase
DA442_17500	ENOG4105FA0	parb-like partition protein
DA442_17505	ENOG4107QJE	Chromosome Partitioning Protein
DA442_17510	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
DA442_17515	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
DA442_17520	ENOG4105QTB	Flavodoxin
DA442_17565	ENOG4105CVR	type I restriction-modification system
DA442_17570	ENOG4105DZR	Type I site-specific deoxyribonuclease
DA442_17595	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
DA442_17600	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
DA442_17605	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
DA442_17610	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
DA442_17615	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
DA442_17630	ENOG4105E5Q	amino acid AbC transporter
DA442_17635	ENOG4105EAB	amino acid AbC transporter
DA442_17660	ENOG4105VEQ	Cold shock protein
DA442_17680	ENOG4105BZU	Histidine kinase
DA442_17695	ENOG4107R34	abc transporter permease protein
DA442_17700	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DA442_17710	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_17715	ENOG4108RMU	ferritin dps family protein
DA442_17730	ENOG4105C0A	alcohol dehydrogenase
DA442_17735	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
DA442_17765	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
DA442_17770	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DA442_17775	ENOG4105MIR	Phenylalanine 4-monooxygenase
DA442_17780	ENOG41090A4	Pterin carbinolamine dehydratase
DA442_17805	ENOG4105VRT	cytoplasmic protein
DA442_17810	ENOG4105C1J	atp-dependent rna helicase
DA442_17815	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
DA442_17820	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
DA442_17830	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
DA442_17840	ENOG4105CKI	cobalamin synthesis protein
DA442_17845	ENOG4105C1J	atp-dependent rna helicase
DA442_17865	ENOG4105CXC	rtn protein
DA442_17870	ENOG4105DKW	ABC transporter
DA442_17875	ENOG4108N3W	hemolysin secretion protein
DA442_17895	ENOG4107S17	Phosphate-binding protein
DA442_17910	ENOG4108ENQ	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction (By similarity)
DA442_17915	ENOG4105C1J	atp-dependent rna helicase
DA442_17920	ENOG4105BZU	Histidine kinase
DA442_17930	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
DA442_17950	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
DA442_17955	ENOG4105CGU	Enoyl-CoA hydratase
DA442_17960	ENOG4107QX3	carboxylase
DA442_17965	ENOG4105C1G	acyl-Coa dehydrogenase
DA442_17975	ENOG4105CHU	acetyl-coa acetyltransferase
DA442_17980	ENOG4105C26	Dehydrogenase
DA442_17990	ENOG4105E39	Enoyl-CoA hydratase
DA442_17995	ENOG4105E39	Enoyl-CoA hydratase
DA442_18000	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DA442_18010	ENOG4105E2S	oxidase) subunit II
DA442_18015	ENOG4105BZ9	Cytochrome C oxidase, subunit I
DA442_18020	ENOG4105CCU	oxidase (Subunit III)
DA442_18030	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
DA442_18035	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DA442_18065	ENOG4105E5Z	arginine transporter ATP-binding subunit
DA442_18070	ENOG4106PMH	Extracellular solute-binding protein family 3
DA442_18075	ENOG4105GBT	ABC transporter
DA442_18080	ENOG4105DMR	ABC, transporter
DA442_18090	ENOG4105DUM	transcriptional regulator, lysR family
DA442_18100	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
DA442_18105	ENOG4107QSN	dihydrolipoamide acetyltransferase
DA442_18110	ENOG4105CPP	Dehydrogenase, E1 component
DA442_18115	ENOG4107RUY	(E1 component), alpha subunit
DA442_18130	ENOG4105R8A	Heat shock protein
DA442_18135	ENOG4106E5D	Protein of unknown function (DUF461)
DA442_18165	ENOG4105DHS	permease protein
DA442_18170	ENOG4105CM4	permease protein
DA442_18175	ENOG4108IPW	abc transporter atp-binding protein
DA442_18180	ENOG4108Z6Z	Transcriptional regulator
DA442_18230	ENOG4105EM2	membrane
DA442_18235	ENOG41088T4	Helicase IV
DA442_18240	ENOG4108Z5K	methylglyoxal synthase
DA442_18245	ENOG4108SV3	Tmao reductase system periplasmic protein tort
DA442_18265	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
DA442_18270	ENOG4105ENH	Sulfatase
DA442_18275	ENOG4105ENH	Sulfatase
DA442_18290	ENOG4105ENH	Sulfatase
DA442_18295	ENOG4105C4X	radical SAM domain protein
DA442_18300	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
DA442_18330	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
DA442_18335	ENOG41064T2	transcriptional regulator, lysR family
DA442_18340	ENOG4107TE5	Lipid kinase
DA442_18345	ENOG4108YDI	single-species biofilm formation on inanimate substrate
DA442_18365	ENOG4105C4X	radical SAM domain protein
DA442_18375	ENOG4105F2V	VRR-NUC domain-containing protein
DA442_18395	ENOG4105D0M	Protease HtpX homolog
DA442_18400	ENOG4108V0P	LemA family
DA442_18405	ENOG4105CEE	C4-dicarboxylate transporter
DA442_18425	ENOG4108MGY	Histidine kinase
DA442_18430	ENOG4107KBT	8-Amino-7-oxononanoate synthase
DA442_18435	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
DA442_18445	ENOG4105KXC	Collagenase
DA442_18455	ENOG4106R3P	AraC family transcriptional regulator
DA442_18530	ENOG4105CDV	Ompa motb domain protein
DA442_18540	ENOG4108WAV	Transcriptional regulator
DA442_18545	ENOG41064T2	transcriptional regulator, lysR family
DA442_18555	ENOG4105BZU	Histidine kinase
DA442_18560	ENOG4105BZU	Histidine kinase
DA442_18565	ENOG4108WQH	regulatoR
DA442_18570	ENOG4105BZU	Histidine kinase
DA442_18580	ENOG4108WQH	regulatoR
DA442_18605	ENOG4107R88	Chemotaxis protein (CheV)
DA442_18625	ENOG4105FR1	rard protein
DA442_18640	ENOG4106CKV	Pap2 superfamily protein
DA442_18660	ENOG4108I0N	Transporter, RarD family, DMT superfamily protein
DA442_18680	ENOG4107RGH	Aldehyde dehydrogenase
DA442_18685	ENOG4107QPK	)-transporter
DA442_18690	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
DA442_18695	ENOG4106YYS	transcriptional regulatory protein
DA442_18715	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
DA442_18745	ENOG4108UYE	Lactoylglutathione lyase
DA442_18765	ENOG4105CJW	magnesium transporter
DA442_18795	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
DA442_18815	ENOG4105HDD	phospholipase
DA442_18840	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
DA442_18845	ENOG4105CR8	Transcriptional regulator
DA442_18855	ENOG4105C5W	Aldolase
DA442_18880	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DA442_18885	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
DA442_18890	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
DA442_18930	ENOG4105DM4	PTS System
DA442_18935	ENOG4105DE4	1-phosphofructokinase
DA442_18940	ENOG4105DTZ	bifunctional PTS system fructose-specific transporter subunit IIA HPr protein
DA442_18945	ENOG4107B7Y	DNA-binding transcriptional regulator FruR
DA442_18965	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
DA442_18970	ENOG4105DRP	amino acid AbC transporter
DA442_18975	ENOG4106TNF	Periplasmic binding protein
DA442_18980	ENOG4105E5Q	amino acid AbC transporter
DA442_18985	ENOG4105CDA	abc transporter atp-binding protein
DA442_18995	ENOG4105CXY	transporter
DA442_19000	ENOG4106JDA	Phosphoglycerate transport regulatory protein PGTC
DA442_19010	ENOG4107TXD	phosphoglycerate transport system transcriptional regulatory protein pgta
DA442_19020	ENOG4108I6A	alcohol dehydrogenase
DA442_19040	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
DA442_19045	ENOG4105CKU	formyltetrahydrofolate synthetase
DA442_19050	ENOG4107RE1	Inosine-guanosine kinase
DA442_19080	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
DA442_19100	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
DA442_19105	ENOG4105C1J	atp-dependent rna helicase
DA442_19110	ENOG4108M8H	domain protein
DA442_19125	ENOG4105DS1	cytochrome b561
DA442_19130	ENOG4108YYC	ycei family
DA442_19135	ENOG4105TMB	Formate nitrite transporter
DA442_19140	ENOG4105DUM	transcriptional regulator, lysR family
DA442_19145	ENOG4108UQ5	membrane protein YcdZ
DA442_19150	ENOG4105CPB	ATP-dependent endonuclease of the OLD family
DA442_19155	ENOG4105CGH	5'-nucleotidase
DA442_19160	ENOG4105DU1	integral membrane protein, terc
DA442_19180	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
DA442_19195	ENOG4105KA0	thioesterase Superfamily protein
DA442_19205	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
DA442_19230	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
DA442_19240	ENOG4105BZU	Histidine kinase
DA442_19245	ENOG4105RKW	reductase (By
DA442_19255	ENOG4108I0Y	(ABC) transporter
DA442_19270	ENOG4107R7A	Allophanate hydrolase subunit 2
DA442_19275	ENOG4105P4J	Allophanate hydrolase, subunit 1
DA442_19280	ENOG4105E7W	lamb ycsf family protein
DA442_19285	ENOG4105BZU	Histidine kinase
DA442_19290	ENOG4105CMR	udp-glucose 4-epimerase
DA442_19305	ENOG4105CWB	LysR family transcriptional Regulator
DA442_19310	ENOG4105CD5	CoA-binding domain protein
DA442_19320	ENOG4105CPF	Cell wall formation (By similarity)
DA442_19330	ENOG4108ZJT	translation initiation factor, Sui1
DA442_19380	ENOG4105MQ5	zona occludens toxin
DA442_19420	ENOG4105EJC	lysr family transcriptional regulator
DA442_19460	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
DA442_19480	ENOG4105BZU	Histidine kinase
DA442_19500	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
DA442_19505	ENOG4105E0C	molybdate abc transporter
DA442_19510	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
DA442_19515	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
DA442_19520	ENOG4105WXI	Bacterial OB fold (BOF) protein
DA442_19530	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
DA442_19535	ENOG4105CGF	Aromatic amino acid aminotransferase
DA442_19540	ENOG4105ECQ	AraC Family Transcriptional Regulator
DA442_19550	ENOG4107QI1	Mate efflux family protein
DA442_19555	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
DA442_19560	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
DA442_19575	ENOG4105BZS	acriflavin resistance protein
DA442_19605	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
DA442_19615	ENOG4105C5Q	Transcriptional regulator
DA442_19620	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
DA442_19625	ENOG4105CXY	transporter
DA442_19630	ENOG4108KX4	response regulator
DA442_19635	ENOG4105BZU	Histidine kinase
DA442_19640	ENOG4105CXY	transporter
DA442_19645	ENOG4105EIP	mannose-6-phosphate isomerase
DA442_19665	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
DA442_19670	ENOG4105K63	Thioredoxin
DA442_19675	ENOG4108ISG	Major Facilitator
DA442_19685	ENOG4107QI1	Mate efflux family protein
DA442_19690	ENOG4105VXR	cytoplasmic protein
DA442_19720	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
DA442_19735	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DA442_19740	ENOG4105TMB	Formate nitrite transporter
DA442_19745	ENOG4105WZK	nitrite reductase NADPH small subunit
DA442_19750	ENOG4107QZF	nitrite reductase NADPH large subunit
DA442_19800	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
DA442_19835	ENOG4108NVR	Methyl-accepting chemotaxis
DA442_19840	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
DA442_19860	ENOG4105CXG	d-lactate dehydrogenase
DA442_19865	ENOG4105CC0	LysR family Transcriptional regulator
DA442_19885	ENOG4105EV2	VWA domain protein interacting with AAA ATPase
DA442_19890	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
DA442_19900	ENOG4105C5W	Aldolase
DA442_19915	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
DA442_19925	ENOG4105C2C	drug resistance transporter, Bcr CflA
DA442_19935	ENOG4105QNF	Outer membrane lipoprotein
DA442_19960	ENOG4107RFY	SbcCD D subunit
DA442_19985	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
DA442_20030	ENOG4108ZF3	Phosphatase
DA442_20045	ENOG4106VK6	Flagellar motor protein
DA442_20065	ENOG4105D9P	serine threonine protein kinase
DA442_20090	ENOG4105F8J	Adenylate Guanylate cyclase
DA442_20105	ENOG4108IG5	Transcriptional regulator
DA442_20125	ENOG4105D7T	ABC transporter
DA442_20165	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
DA442_20180	ENOG4105C44	Serine transporter
DA442_20190	ENOG4105BZU	Histidine kinase
DA442_20225	ENOG4105ETX	regulatoR
DA442_20245	ENOG4108I5U	Uridine phosphorylase
DA442_20260	ENOG4105ETE	Transcriptional regulator (LacI family
DA442_20265	ENOG4108RVA	ribokinase
DA442_20270	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
DA442_20280	ENOG4105C2J	ABC transporter
DA442_20285	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
DA442_20290	ENOG4108K0B	C-di-gmp phosphodiesterase
DA442_20295	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
DA442_20355	ENOG4105BZU	Histidine kinase
DA442_20360	ENOG4105CA0	peroxidase
DA442_20375	ENOG4105BZU	Histidine kinase
DA442_20390	ENOG4107QX8	SPFH domain, Band 7 family protein
DA442_20400	ENOG4108RCM	Nitroreductase
DA442_20405	ENOG4108IJ7	Glycine betaine
DA442_20410	ENOG4108HQS	Glycine betaine
DA442_20420	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
DA442_20425	ENOG4105C26	Dehydrogenase
DA442_20430	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
DA442_20435	ENOG4105BZU	Histidine kinase
DA442_20450	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DA442_20460	ENOG4105E39	Enoyl-CoA hydratase
DA442_20470	ENOG4105C26	Dehydrogenase
DA442_20475	ENOG4105CHU	acetyl-coa acetyltransferase
DA442_20485	ENOG4105C1G	acyl-Coa dehydrogenase
DA442_20495	ENOG4108UKI	Enoyl-CoA hydratase
DA442_20505	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
DA442_20510	ENOG4105BZU	Histidine kinase
DA442_20525	ENOG4105EGS	Mechanosensitive ion channel
DA442_20535	ENOG4108UW5	maltose o-acetyltransferase
DA442_20540	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DA442_20545	ENOG4105C4M	(Ubiquinol oxidase) subunit I
DA442_20550	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
DA442_20560	ENOG4108S58	Phenazine biosynthesis protein PhzF
DA442_20565	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
DA442_20570	ENOG4105VUF	Transcriptional regulator
DA442_20580	ENOG4105G9V	cytochrome C
DA442_20585	ENOG4105DQU	oxidoreductase, subunit beta
DA442_20590	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
DA442_20605	ENOG4105DZS	Phenylacetate-CoA ligase
DA442_20610	ENOG4108IV0	ABC, transporter
DA442_20635	ENOG4105C0Z	ABC transporter
DA442_20645	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
DA442_20650	ENOG4105BZJ	Electron transfer flavoprotein
DA442_20655	ENOG4105C10	Electron transfer flavoprotein
DA442_20660	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
DA442_20665	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
DA442_20670	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
DA442_20680	ENOG4108UNF	response regulator
DA442_20685	ENOG4107RGM	aldo keto reductase
DA442_20700	ENOG4105CMQ	Chloride channel
DA442_20710	ENOG4105C5A	transporter
DA442_20720	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
DA442_20725	ENOG4105D06	uba thif-type nad fad binding protein
DA442_20745	ENOG4105KHC	sulfurtransferase
DA442_20750	ENOG4105BZU	Histidine kinase
DA442_20775	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
DA442_20780	ENOG4105CV1	Transketolase (EC 2.2.1.1)
DA442_20795	ENOG4105DXI	Major Facilitator superfamily
DA442_20800	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
DA442_20810	ENOG4105UYK	outer membrane protein a
DA442_20815	ENOG4107VXZ	Hydrolase
DA442_20820	ENOG4108YZN	class I peptide chain release factor
DA442_20825	ENOG4108N3W	hemolysin secretion protein
DA442_20840	ENOG4107YWA	deoxycytidylate deaminase
DA442_20845	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
DA442_20860	ENOG4105WH1	Two component transcriptional regulator luxr family
DA442_20865	ENOG4105BZU	Histidine kinase
DA442_20880	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
DA442_20890	ENOG4105CUW	cytochrome C-TYPE protein
DA442_20900	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
DA442_20910	ENOG4105CHU	acetyl-coa acetyltransferase
DA442_20930	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DA442_20935	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
DA442_20965	ENOG4105EW9	transcriptional regulator AsnC family
DA442_20985	ENOG4105EFX	secretion protein, HlyD family
DA442_20995	ENOG4105BZU	Histidine kinase
DA442_21000	ENOG4108QGH	periplasmic
DA442_21005	ENOG41082IR	Excinuclease ABC C subunit domain protein
DA442_21010	ENOG4108YXG	UPF0502 protein
DA442_21025	ENOG41090HJ	UPF0265 protein
DA442_21040	ENOG4105BZU	Histidine kinase
DA442_21065	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
DA442_21070	ENOG4108XM1	transcriptional regulator AsnC family
DA442_21080	ENOG4105DVH	amino acid
DA442_21095	ENOG4105E0F	Histidine kinase
DA442_21100	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
DA442_21125	ENOG4105EFX	secretion protein, HlyD family
DA442_21130	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
DA442_21135	ENOG4105CJW	magnesium transporter
DA442_21145	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
DA442_21150	ENOG4105DZC	cytosine deaminase
DA442_21160	ENOG4105EST	Metal Dependent Phosphohydrolase
DA442_21175	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
DA442_21185	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
DA442_21205	ENOG4108Z33	Thiol disulfide Interchange Protein
DA442_21225	ENOG4105EMU	Dehydrogenase
DA442_21230	ENOG4107EXC	regulatoR
DA442_21235	ENOG4105JJR	Histidine kinase
DA442_21245	ENOG41080IJ	Diacylglycerol kinase
DA442_21250	ENOG4105DIJ	Phosphoethanolamine transferase
DA442_21255	ENOG4105EP9	oxidoreductase
DA442_21280	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
DA442_21290	ENOG4108NRW	Phospholipase, patatin family
DA442_21295	ENOG4105EUB	pirin domain protein
DA442_21300	ENOG4105VEQ	Cold shock protein
DA442_21320	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
DA442_21345	ENOG4105DZ1	carboxypeptidase
DA442_21360	ENOG4105CYM	Glutathione S-transferase
DA442_21395	ENOG4105CHR	reductase
DA442_21415	ENOG4108P3C	
DA442_21435	ENOG4105EG2	ABC transporter, permease
DA442_21440	ENOG4105D56	permease protein
DA442_21445	ENOG4107FKK	extracellular solute-binding protein family 1
DA442_21450	ENOG4108IJ9	(ABC) transporter
DA442_21510	ENOG4105V0I	UPF0267 protein
DA442_21515	ENOG4108WUH	Transcriptional regulator, TetR family
DA442_21520	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
DA442_21525	ENOG4108RXX	maleylacetoacetate isomerase
DA442_21530	ENOG4105CH6	catalase
DA442_21535	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
DA442_21545	ENOG4108YRF	PTS System
DA442_21555	ENOG4106R3P	AraC family transcriptional regulator
DA442_21565	ENOG4105EIP	mannose-6-phosphate isomerase
DA442_21575	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
DA442_21585	ENOG4105BZU	Histidine kinase
DA442_21590	ENOG4105CZN	Potassium uptake protein
DA442_21605	ENOG4105BZU	Histidine kinase
DA442_21610	ENOG4105BZ1	(ABC) transporter
DA442_21615	ENOG4105E0K	tonB-dependent siderophore receptor
DA442_21620	ENOG4105E0A	ABC, transporter
DA442_21630	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
DA442_21640	ENOG4105KCK	Peptidoglycan-associated lipoprotein
DA442_21660	ENOG4108JJ6	Type I secretion system ATPase
DA442_21670	ENOG41086KC	Transcriptional regulator
DA442_21675	ENOG41086KC	Transcriptional regulator
DA442_21685	ENOG41069D7	Methyl-accepting chemotaxis
DA442_21695	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
DA442_21730	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
DA442_21735	ENOG4105E2Z	phosphate ABC transporter (Permease
DA442_21740	ENOG4105C8U	phosphate abc transporter
DA442_21745	ENOG4107S17	Phosphate-binding protein
DA442_21750	ENOG4108NVR	Methyl-accepting chemotaxis
DA442_21770	ENOG4105D05	Receptor
DA442_21775	ENOG4105CUG	Oligopeptidase b
DA442_21780	ENOG4105C1J	atp-dependent rna helicase
DA442_21790	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
DA442_21795	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
DA442_21800	ENOG4108XDN	Transcriptional regulator
DA442_21805	ENOG4107SEY	Conserved Protein
DA442_21815	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
DA442_21830	ENOG4106TD9	Diguanylate cyclase
DA442_21835	ENOG4105KK7	inner membrane protein YiaW
DA442_21840	ENOG4105EFX	secretion protein, HlyD family
DA442_21845	ENOG4108V7D	UPF0397 protein
DA442_21850	ENOG4108JJB	ABC transporter
DA442_21865	ENOG4105GXZ	Ferredoxin-type protein NapH
DA442_21870	ENOG4108BGM	Quinol dehydrogenase periplasmic component
DA442_21875	ENOG4105WCN	acetyltransferase
DA442_21895	ENOG4105YE1	PilZ domain
DA442_21900	ENOG4108NVR	Methyl-accepting chemotaxis
DA442_21905	ENOG4105DAN	ATP-dependent protease
DA442_21915	ENOG4108JQ5	ABC transporter
DA442_21925	ENOG4105CR8	Transcriptional regulator
DA442_21930	ENOG4105DAA	L-lactate
DA442_21935	ENOG4105DMF	Dehydrogenase
DA442_21945	ENOG4105D64	Mechanosensitive ion channel
DA442_21985	ENOG4105CPQ	Dehydrogenase
DA442_21990	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
DA442_21995	ENOG4105BZU	Histidine kinase
DA442_22000	ENOG4107R0W	ABC transporter
DA442_22010	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
DA442_22020	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
DA442_22050	ENOG4105EXG	Transcriptional regulator
DA442_22055	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
DA442_22075	ENOG4107SSZ	Phosphatase
DA442_22105	ENOG4108JIR	Flagellum-specific ATP synthase
DA442_22115	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
DA442_22120	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
DA442_22130	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DA442_22145	ENOG4105DD5	Flagellar motor switch protein
DA442_22150	ENOG4105CN7	Flagellar biosynthetic protein FliP
DA442_22155	ENOG4105VS8	Flagellar biosynthetic protein fliq
DA442_22165	ENOG4105D00	flagellar biosynthetic protein flhB
DA442_22180	ENOG4105I03	Flagellin
DA442_22190	ENOG410804A	Flagellar hook-associated 2 domain-containing protein
DA442_22195	ENOG4105MQ3	flagellar protein FliS
DA442_22220	ENOG4107RD7	Flagellar Motor Protein, MotA
DA442_22235	ENOG4105KWG	Pfam:DUF1696
DA442_22255	ENOG4105C6N	Formate acetyltransferase
DA442_22260	ENOG4105F1A	Pyruvate formate-lyase
DA442_22275	ENOG4105I4A	GCN5-related N-acetyltransferase
DA442_22285	ENOG4105CNH	Multidrug resistance protein MdtL
DA442_22290	ENOG4105G2Y	Transcriptional regulator
DA442_22330	ENOG4105IPI	Membrane
DA442_22335	ENOG41068P6	UPF0319 protein
DA442_22345	ENOG4105DP0	ferredoxin-NADP reductase
DA442_22355	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
DA442_22360	ENOG4105ETT	transcriptional Regulator, LysR family
DA442_22370	ENOG4108RCM	Nitroreductase
DA442_22375	ENOG4108ZX5	transcriptional regulator
DA442_22385	ENOG4105DZ1	carboxypeptidase
DA442_22400	ENOG4105C72	UPF0176 protein
DA442_22405	ENOG4108M1A	Chitin-binding protein
DA442_22410	ENOG4108NRW	Phospholipase, patatin family
DA442_22415	ENOG41081FY	multiple antibiotic resistance (MarC)-related
DA442_22425	ENOG4105DAY	polysaccharide export protein
DA442_22435	ENOG4105D75	Capsular exopolysaccharide family
DA442_22445	ENOG4105N0V	mono-oxygenase ydhR
DA442_22450	ENOG4105F04	LysR family Transcriptional regulator
DA442_22460	ENOG4105CK2	sodium dicarboxylate symporter
DA442_22470	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
DA442_22475	ENOG4108P2H	Inner membrane protein YjiG
DA442_22480	ENOG41074DU	domain protein
DA442_22495	ENOG4107T9C	Alpha amylase catalytic region
DA442_22500	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
DA442_22505	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
DA442_22510	ENOG4107RTM	4-alpha-glucanotransferase (EC 2.4.1.25)
DA442_22515	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
DA442_22530	ENOG41061ZR	Transcriptional regulator
DA442_22560	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
DA442_22565	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
DA442_22575	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
DA442_22585	ENOG4105D5Q	Arginine ornithine antiporter
DA442_22590	ENOG4105CXN	decarboxylase
DA442_22610	ENOG4108K8S	endonuclease I
DA442_22635	ENOG4108KDD	Involved in the transport of maltose and maltodextrins (By similarity)
DA442_22660	ENOG4105DR5	peptidase
DA442_22670	ENOG4107RAN	Peptidase, M16
DA442_22675	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_22680	ENOG4105E0A	ABC, transporter
DA442_22685	ENOG4108U1V	ABC transporter, permease
DA442_22690	ENOG4105DQ5	transport system permease protein
DA442_22695	ENOG4108HUF	Transporter
DA442_22700	ENOG4105GAV	receptor
DA442_22705	ENOG4105E0K	tonB-dependent siderophore receptor
DA442_22715	ENOG4105DUU	IucA IucC family protein
DA442_22725	ENOG4105DBM	Siderophore biosynthesis protein
DA442_22730	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
DA442_22735	ENOG4108JP0	extracellular solute-binding protein family 1
DA442_22740	ENOG4105DHQ	Histidine kinase
DA442_22745	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
DA442_22755	ENOG4105CI1	PTS System
DA442_22770	ENOG4105CNN	ABC, transporter
DA442_22775	ENOG4105C2J	ABC transporter
DA442_22780	ENOG4105DMK	Periplasmic binding protein LacI transcriptional regulator
DA442_22795	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
DA442_22820	ENOG4108ZHJ	Organic hydroperoxide resistance protein
DA442_22825	ENOG4105K56	Transcriptional regulator
DA442_22830	ENOG4105D3R	alkyl hydroperoxide reductase
DA442_22835	ENOG4108JU3	Alkyl hydroperoxide reductase
DA442_22865	ENOG4105EXG	Transcriptional regulator
DA442_22875	ENOG4105ECQ	AraC Family Transcriptional Regulator
DA442_22880	ENOG4105DU6	RNA polymerase
DA442_22895	ENOG4108N3W	hemolysin secretion protein
DA442_22900	ENOG4105W8I	Transcriptional regulator
DA442_22905	ENOG4105F8D	glycoside hydrolase family 4
DA442_22920	ENOG4108RPX	mosc domain containing protein
DA442_22925	ENOG4105C1J	atp-dependent rna helicase
DA442_22930	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
DA442_22935	ENOG4105C6F	GntR Family Transcriptional Regulator
DA442_22940	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
DA442_22945	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
DA442_22950	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
DA442_22955	ENOG4105DEI	Mannitol dehydrogenase
DA442_22960	ENOG4105D2H	Uronic isomerase
DA442_22965	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
DA442_22970	ENOG4108UHU	Aldolase
DA442_22975	ENOG4105P66	Membrane
DA442_22995	ENOG4105CF7	AraC family transcriptional regulator
DA442_23005	ENOG4105BZ1	(ABC) transporter
DA442_23015	ENOG4105EW9	transcriptional regulator AsnC family
DA442_23050	ENOG4105CK7	Sodium proline symporter
DA442_23060	ENOG4105C26	Dehydrogenase
DA442_23080	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
DA442_23085	ENOG4105CQZ	Histidine kinase
DA442_23090	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DA442_23095	ENOG4107QZV	Type I secretion membrane fusion protein
DA442_23110	ENOG4108JJA	ABC, transporter
DA442_23125	ENOG4108J59	Extracellular solute-binding protein, family 5
DA442_23135	ENOG4108PSC	Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of MurQ, is the specific inducer that weakens binding of MurR to the operator (By similarity)
DA442_23145	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
DA442_23150	ENOG4105C5Y	PTS System
DA442_23155	ENOG4105FCK	Membrane
DA442_23160	ENOG4105EC3	peptidase S51, dipeptidase E
DA442_23180	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
DA442_23185	ENOG4106RMF	ParB family
DA442_23210	ENOG4108JQ7	(ABC) transporter
DA442_23240	ENOG4105BZU	Histidine kinase
DA442_23250	ENOG4105CDY	transcriptional regulatory protein
DA442_23255	ENOG4105CNI	cell division protein FtsW
DA442_23270	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
DA442_23290	ENOG4108HRK	Histidine kinase
DA442_23295	ENOG4108VAC	response regulator
DA442_23305	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
DA442_23310	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_23340	ENOG4105D6U	Sodium Glutamate Symporter
DA442_23350	ENOG4105DVE	abc transporter atp-binding protein
DA442_23355	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DA442_23360	ENOG4105D6U	Sodium Glutamate Symporter
DA442_23375	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
DA442_23395	ENOG4105C2I	pirin domain protein
DA442_23400	ENOG4108VGI	doxx family
DA442_23415	ENOG4105D03	DNA-3-methyladenine glycosylase II
DA442_23420	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
DA442_23440	ENOG4105DN9	Na H antiporter
DA442_23470	ENOG4105NBK	UPF0345 protein
DA442_23490	ENOG4105UQX	Mate efflux family protein
DA442_23495	ENOG4105D3G	Pseudouridine synthase
DA442_23510	ENOG4105EJC	lysr family transcriptional regulator
DA442_23515	ENOG4108HCJ	Hydrolase
DA442_23525	ENOG4108KHX	Diguanylate cyclase
DA442_23535	ENOG4105C4W	S-formylglutathione hydrolase
DA442_23545	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
DA442_23550	ENOG4105CC0	LysR family Transcriptional regulator
DA442_23565	ENOG4105J4Q	Transcriptional regulator
DA442_23570	ENOG4105CHR	reductase
DA442_23580	ENOG4105M5J	Cupin 2, conserved barrel domain protein
DA442_23595	ENOG4107SS6	2-dehydro-3-deoxygluconokinase
DA442_23600	ENOG4108UHU	Aldolase
DA442_23625	ENOG4105CAZ	oligogalacturonide lyase
DA442_23630	ENOG4105Q26	Siderophore-interacting protein
DA442_23640	ENOG4105EW9	transcriptional regulator AsnC family
DA442_23645	ENOG4108M1A	Chitin-binding protein
DA442_23660	ENOG4107W31	Pentapeptide repeat protein
DA442_23665	ENOG4105EIF	outer membrane protein W
DA442_23675	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
DA442_23695	ENOG4107WCA	isomerase
DA442_23700	ENOG4108UVJ	appr-1-p processing domain protein
DA442_23705	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
DA442_23710	ENOG4108WAV	Transcriptional regulator
DA442_23755	ENOG4108IXP	Carbohydrate diacid transcriptional activator CdaR
DA442_23760	ENOG4105C6Z	Gluconate
DA442_23765	ENOG4105BZW	Glycerate kinase
DA442_23805	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
DA442_23815	ENOG4105CUW	cytochrome C-TYPE protein
DA442_23820	ENOG4107QY8	reductase
DA442_23830	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
DA442_23835	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
DA442_23840	ENOG4105ETU	transcriptional activator (TenA
DA442_23845	ENOG4107Z6I	Thiamine biosynthesis protein
DA442_23850	ENOG4105Y36	Binding-protein-dependent transport systems, inner membrane component
DA442_23855	ENOG4108YI8	ABC transporter
DA442_23860	ENOG4105DWF	phosphomethylpyrimidine kinase
DA442_23880	ENOG4108TEM	pseudouridine methyltransferase
DA442_23935	ENOG4108YYI	Protein of unknown function (DUF2810)
DA442_23940	ENOG4105C5I	Dehydrogenase
DA442_23950	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
DA442_23955	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
DA442_23960	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
DA442_23965	ENOG410804D	Sensor Signal Transduction Histidine Kinase
DA442_23990	ENOG4109015	Biopolymer transport protein exbD tolR
DA442_24030	ENOG4105DSE	periplasmic solute binding protein
DA442_24035	ENOG4105DIK	(ABC) transporter
DA442_24040	ENOG4105CC5	ABC transporter
DA442_24055	ENOG4105CUG	Oligopeptidase b
DA442_24060	ENOG4105E5M	Multidrug resistance protein D
DA442_24065	ENOG4105CYW	agmatinase
DA442_24070	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
DA442_24080	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
DA442_24085	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
DA442_24095	ENOG4105DUM	transcriptional regulator, lysR family
DA442_24130	ENOG4105CQZ	Histidine kinase
DA442_24135	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
DA442_24145	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
DA442_24170	ENOG4105D5U	fad dependent oxidoreductase
DA442_24180	ENOG4105C0F	tryptophanase EC 4.1.99.1
DA442_24200	ENOG4105D9N	nucleoside
DA442_24210	ENOG4105CF1	Alkylated DNA repair protein
DA442_24215	ENOG4105BZU	Histidine kinase
DA442_24220	ENOG4108N3W	hemolysin secretion protein
DA442_24235	ENOG4106TD9	Diguanylate cyclase
DA442_24240	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
DA442_24245	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
DA442_24260	ENOG4105E0X	reductase
DA442_24265	ENOG4108UKZ	OsmC family
DA442_24270	ENOG4108UW5	maltose o-acetyltransferase
DA442_24305	ENOG4105JQN	Transcriptional regulator
DA442_24310	ENOG4105PAD	Hydrolase
DA442_24325	ENOG4108UUE	Transcriptional regulator
DA442_24335	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
DA442_24340	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
DA442_24345	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
DA442_24355	ENOG4105KUU	lipolytic protein G-D-S-L family
DA442_24360	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
DA442_24385	ENOG4105ETE	Transcriptional regulator (LacI family
DA442_24390	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
DA442_24395	ENOG4108JPW	Aminotransferase
DA442_24420	ENOG4107RCV	ABC transporter, permease
DA442_24440	ENOG4108MJ5	VirK protein
DA442_24450	ENOG4105CJP	fad dependent oxidoreductase
DA442_24470	ENOG4105ETT	transcriptional Regulator, LysR family
DA442_24495	ENOG4105EJQ	L-serine dehydratase
DA442_24515	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
DA442_24525	ENOG4105E4C	Lytic transglycosylase catalytic
DA442_24545	ENOG4105Q75	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
DA442_24550	ENOG4108ZC9	flagellar basal-body rod protein flgc
DA442_24555	ENOG4105W00	Flagellar hook capping protein
DA442_24560	ENOG4105BZE	flagellar hook protein, FlgE
DA442_24565	ENOG4108KPB	Flagellar basal-body rod protein FlgF
DA442_24570	ENOG4105CGA	flagellar basal-body rod protein FlgG
DA442_24575	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
DA442_24580	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
DA442_24585	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
DA442_24595	ENOG4105DTJ	flagellar hook-associated protein
DA442_24615	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
DA442_24630	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
DA442_24640	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
DA442_24655	ENOG4105N14	lysine exporter protein LysE YggA
DA442_24675	ENOG4107Z3H	Transcriptional regulator, TetR family
DA442_24685	ENOG4105CGH	5'-nucleotidase
DA442_24690	ENOG4105EA8	2-Nitropropane dioxygenase
DA442_24700	ENOG4105CWX	Alpha-1,2-mannosidase
DA442_24710	ENOG4105CWX	Alpha-1,2-mannosidase
DA442_24715	ENOG4105CWX	Alpha-1,2-mannosidase
DA442_24720	ENOG4105DM4	PTS System
DA442_24735	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
DA442_24740	ENOG4105KHA	Glyoxalase Bleomycin resistance protein (Dioxygenase
DA442_24745	ENOG4105N2W	Transcriptional regulator
DA442_24755	ENOG4105CH6	catalase
DA442_24765	ENOG4108RWI	nicotinamidase
DA442_24775	ENOG4107RH7	Nicotinate phosphoribosyltransferase
DA442_24805	ENOG4105ETT	transcriptional Regulator, LysR family
DA442_24820	ENOG4105RW8	MltA-interacting MipA family protein
DA442_24830	ENOG4107EII	Lipoprotein involved with copper homeostasis and adhesion
DA442_24835	ENOG4105VYW	UPF0251 protein
DA442_24860	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
DA442_24880	ENOG4105RQF	LysR family Transcriptional regulator
DA442_24900	ENOG4108Z4X	TRANSCRIPTIONal
DA442_24930	ENOG4107RZC	phospholipase d
DA442_24975	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
DA442_25015	ENOG41086KC	Transcriptional regulator
DA442_25025	ENOG4105BZU	Histidine kinase
DA442_25045	ENOG4107KET	secretion protein, HlyD family
DA442_25060	ENOG4107RUE	extracellular solute-binding protein family 1
DA442_25065	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
DA442_25085	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
DA442_25090	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
DA442_25095	ENOG4105HDK	L-asparaginase
DA442_25100	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
DA442_25125	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
DA442_25135	ENOG4108ZX5	transcriptional regulator
DA442_25140	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
DA442_25150	ENOG4105CPQ	Dehydrogenase
DA442_25155	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
DA442_25170	ENOG4107RSM	transcriptional regulator
DA442_25180	ENOG4105C1J	atp-dependent rna helicase
DA442_25225	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
DA442_25230	ENOG410874W	AraC family transcriptional regulator
DA442_25260	ENOG4105CKW	Inner membrane protein yedI
DA442_25265	ENOG4105EKE	dihydroorotase
DA442_25285	ENOG4105QVC	MOSC domain-containing protein
DA442_25285	ENOG4105QVC	MOSC domain-containing protein
DA442_25290	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
DA442_25295	ENOG4107X4V	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
DA442_25335	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
DA442_25340	ENOG4105EHG	Permease protein
DA442_25350	ENOG4106GFD	transport protein
DA442_25355	ENOG41090AP	transport protein
DA442_25360	ENOG4105WQ5	TonB family
DA442_25365	ENOG4105D4P	Coproporphyrinogen iii oxidase
DA442_25370	ENOG41090JE	Utilization Protein
DA442_25375	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
DA442_25385	ENOG4107R88	Chemotaxis protein (CheV)
DA442_25395	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
DA442_25420	ENOG4107QRT	dEAD DEAH box helicase
DA442_25445	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
DA442_25460	ENOG4105C5Q	Transcriptional regulator
DA442_25475	ENOG4105KXC	Collagenase
DA442_25505	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
DA442_25510	ENOG4108M6U	Universal stress protein A
DA442_25515	ENOG4105C5H	ABC transporter
DA442_25530	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
DA442_25540	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
DA442_25550	ENOG4108HK0	-acetyltransferase
DA442_25560	ENOG410620I	Diguanylate cyclase
DA442_25580	ENOG4108IJF	Heavy metal efflux pump, CzcA
DA442_25605	ENOG4108IEG	Formate dehydrogenase Alpha subunit
DA442_25620	ENOG4107QWP	ABC-2 type transporter
DA442_25625	ENOG4105CJ1	ABC, transporter
DA442_25635	ENOG4108NVR	Methyl-accepting chemotaxis
DA442_25645	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
DA442_25650	ENOG4105JAB	phenazine biosynthesis protein, phzf family
DA442_25655	ENOG4108V1U	phospholipid-binding protein
DA442_25665	ENOG4105D6J	arsenicaL-resistance protein
DA442_25685	ENOG4108X7Y	Mannitol-specific cryptic phosphotransferase enzyme iia
DA442_25690	ENOG4105CTS	PTS system mannitol-specific
DA442_25695	ENOG4105DXH	Alcohol dehydrogenase zinc-binding domain protein
DA442_25705	ENOG4107Z1W	Fructose transport system kinase
DA442_25730	ENOG4105E0U	tyrosine-specific transport protein
DA442_25740	ENOG4105C8Q	Methyl-accepting chemotaxis
DA442_25745	ENOG4105DWD	nucleoside recognition domain protein
DA442_25770	ENOG4105DR5	peptidase
DA442_25780	ENOG4105CR8	Transcriptional regulator
DA442_25785	ENOG4105E5M	Multidrug resistance protein D
DA442_25805	ENOG4105VW4	glutaredoxin 3
DA442_25810	ENOG4108SXK	Transporter Drug Metabolite Exporter family
DA442_25840	ENOG4105SUT	Transcriptional Regulator AraC Family
DA442_25870	ENOG4105FT1	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I (By similarity)
DA442_25875	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
DA442_25895	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
DA442_25900	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
DA442_25905	ENOG4108V1T	peptidylprolyl cis-trans isomerase