locus-tag	class	description
JHT10_00020	COG0641	radical SAM
JHT10_00040	COG0840	transmembrane signaling receptor activity
JHT10_00045	COG1119	ATPase activity
JHT10_00050	COG2200	EAL domain
JHT10_00070	COG0513	Belongs to the DEAD box helicase family
JHT10_00075	COG0523	cobalamin synthesis protein
JHT10_00085	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JHT10_00095	COG0133	tryptophan synthase activity
JHT10_00100	COG4628	conserved protein (DUF2132)
JHT10_00105	COG0513	Belongs to the DEAD box helicase family
JHT10_00110	COG3530	Putative quorum-sensing-regulated virulence factor
JHT10_00130	COG2154	pterin-4-alpha-carbinolamine dehydratase
JHT10_00135	COG3186	Phenylalanine-4-hydroxylase
JHT10_00140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JHT10_00145	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JHT10_00185	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JHT10_00190	COG1454	alcohol dehydrogenase
JHT10_00195	COG2133	pyrroloquinoline quinone binding
JHT10_00205	COG0783	Belongs to the Dps family
JHT10_00210	COG0840	transmembrane signaling receptor activity
JHT10_00220	COG1136	(ABC) transporter
JHT10_00220	COG0577	efflux transmembrane transporter activity
JHT10_00240	COG2199	diguanylate cyclase activity
JHT10_00250	COG3036	rescue of stalled ribosome
JHT10_00255	COG1278	Cold shock
JHT10_00285	COG0545	Peptidyl-prolyl cis-trans isomerase
JHT10_00290	COG0109	protoheme IX farnesyltransferase activity
JHT10_00295	COG1612	heme a metabolic process
JHT10_00320	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JHT10_00330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JHT10_00335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHT10_00345	COG1280	lysine exporter protein (LysE YggA)
JHT10_00375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JHT10_00380	COG0697	spore germination
JHT10_00395	COG2814	Major facilitator Superfamily
JHT10_00400	COG0583	DNA-binding transcription factor activity
JHT10_00405	COG5001	Diguanylate cyclase
JHT10_00410	COG0739	heme binding
JHT10_00430	COG3314	Sporulation integral membrane protein YlbJ
JHT10_00445	COG0814	amino acid
JHT10_00465	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JHT10_00470	COG1072	(Pantothenic acid kinase))
JHT10_00480	COG1063	alcohol dehydrogenase
JHT10_00485	COG2213	PTS system mannitol-specific
JHT10_00490	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_00505	COG0798	PFAM Bile acid sodium symporter
JHT10_00515	COG1881	PFAM PEBP family protein
JHT10_00525	COG2706	6-phosphogluconolactonase activity
JHT10_00540	COG1131	(ABC) transporter
JHT10_00545	COG0842	Transport permease protein
JHT10_00560	COG3383	formate dehydrogenase (NAD+) activity
JHT10_00580	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_00610	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHT10_00620	COG2067	long-chain fatty acid transport protein
JHT10_00630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_00640	COG1505	serine-type exopeptidase activity
JHT10_00645	COG0488	(ABC) transporter
JHT10_00650	COG0589	response to stress
JHT10_00655	COG2249	NAD(P)H dehydrogenase (quinone) activity
JHT10_00675	COG0366	Alpha amylase catalytic
JHT10_00685	COG4934	collagen metabolic process
JHT10_00700	COG0583	DNA-binding transcription factor activity
JHT10_00705	COG0783	Belongs to the Dps family
JHT10_00710	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JHT10_00735	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JHT10_00735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHT10_00745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JHT10_00750	COG0784	Response regulator, receiver
JHT10_00750	COG0835	chemotaxis
JHT10_00760	COG0748	coenzyme F420 binding
JHT10_00765	COG3721	Heme iron utilization protein
JHT10_00775	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JHT10_00780	COG0811	peptide transport
JHT10_00785	COG0848	biopolymer transport protein
JHT10_00795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHT10_00800	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JHT10_00840	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JHT10_00845	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JHT10_00850	COG3217	Mosc domain protein beta barrel domain protein
JHT10_00850	COG3217	Mosc domain protein beta barrel domain protein
JHT10_00850	COG0633	Ferredoxin
JHT10_00850	COG0633	Ferredoxin
JHT10_00855	COG0401	homolog of Blt101
JHT10_00860	COG0418	dihydroorotase activity
JHT10_00865	COG2354	Protein conserved in bacteria
JHT10_00895	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JHT10_00895	COG2207	Transcriptional regulator
JHT10_00900	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHT10_00940	COG0513	Belongs to the DEAD box helicase family
JHT10_00950	COG0583	DNA-binding transcription factor activity
JHT10_00965	COG1902	pentaerythritol trinitrate reductase activity
JHT10_00970	COG1063	alcohol dehydrogenase
JHT10_00980	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_00990	COG3122	Protein conserved in bacteria
JHT10_01010	COG0583	DNA-binding transcription factor activity
JHT10_01015	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JHT10_01020	COG0252	asparaginase activity
JHT10_01025	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JHT10_01030	COG0574	Belongs to the PEP-utilizing enzyme family
JHT10_01030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JHT10_01045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JHT10_01065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_01085	COG3706	GGDEF domain
JHT10_01105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHT10_01135	COG3842	ATPase activity
JHT10_01165	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHT10_01200	COG0583	DNA-binding transcription factor activity
JHT10_01210	COG4948	Mandelate Racemase Muconate Lactonizing
JHT10_01240	COG1342	Belongs to the UPF0251 family
JHT10_01245	COG3015	lipoprotein NlpE involved in copper resistance
JHT10_01250	COG3713	MltA-interacting MipA family protein
JHT10_01265	COG0583	DNA-binding transcription factor activity
JHT10_01290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JHT10_01300	COG1335	isochorismatase
JHT10_01310	COG0753	catalase activity
JHT10_01320	COG1349	DNA-binding transcription factor activity
JHT10_01325	COG0346	lactoylglutathione lyase activity
JHT10_01345	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_01350	COG3537	Alpha-1,2-mannosidase
JHT10_01355	COG3537	Alpha-1,2-mannosidase
JHT10_01365	COG3537	Alpha-1,2-mannosidase
JHT10_01370	COG3537	Alpha-1,2-mannosidase
JHT10_01380	COG0737	Belongs to the 5'-nucleotidase family
JHT10_01390	COG1309	transcriptional regulator
JHT10_01410	COG1280	lysine exporter protein (LysE YggA)
JHT10_01425	COG0459	protein refolding
JHT10_01430	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JHT10_01435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHT10_01460	COG1304	FMN binding
JHT10_01480	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_01485	COG1256	bacterial-type flagellum assembly
JHT10_01485	COG4786	Flagellar basal body rod
JHT10_01495	COG1706	bacterial-type flagellum-dependent cell motility
JHT10_01500	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JHT10_01505	COG4786	Flagellar basal body rod
JHT10_01510	COG4787	bacterial-type flagellum-dependent cell motility
JHT10_01515	COG1749	Flagellar hook protein flgE
JHT10_01520	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JHT10_01525	COG1558	bacterial-type flagellum-dependent cell motility
JHT10_01530	COG1815	bacterial-type flagellum-dependent cell motility
JHT10_01550	COG0741	lytic transglycosylase activity
JHT10_01555	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JHT10_01575	COG1760	l-serine dehydratase
JHT10_01580	COG3104	oligopeptide transport
JHT10_01600	COG0583	DNA-binding transcription factor activity
JHT10_01610	COG2866	Carboxypeptidase
JHT10_01615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JHT10_01620	COG2990	Protein conserved in bacteria
JHT10_01645	COG3842	ATPase activity
JHT10_01655	COG1840	ABC-type Fe3 transport system, periplasmic component
JHT10_01660	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JHT10_01665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHT10_01670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHT10_01675	COG1609	Transcriptional regulator
JHT10_01705	COG3240	lipase activity
JHT10_01715	COG1136	(ABC) transporter
JHT10_01715	COG0577	efflux transmembrane transporter activity
JHT10_01720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_01725	COG2067	long-chain fatty acid transport protein
JHT10_01735	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JHT10_01750	COG1011	Hydrolase
JHT10_01790	COG0110	maltose O-acetyltransferase activity
JHT10_01795	COG1765	OsmC-like protein
JHT10_01825	COG1765	OsmC-like protein
JHT10_01830	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHT10_01830	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHT10_01845	COG3046	protein related to deoxyribodipyrimidine photolyase
JHT10_01850	COG0415	Belongs to the DNA photolyase family
JHT10_01855	COG3706	GGDEF domain
JHT10_01870	COG0840	transmembrane signaling receptor activity
JHT10_01875	COG3706	GGDEF domain
JHT10_01890	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHT10_01905	COG3033	Beta-eliminating lyase
JHT10_01915	COG0579	oxidoreductase
JHT10_01930	COG1114	Component of the transport system for branched-chain amino acids
JHT10_01935	COG2199	diguanylate cyclase activity
JHT10_01975	COG0583	DNA-binding transcription factor activity
JHT10_01980	COG0189	ligase activity
JHT10_01985	COG4067	protein conserved in archaea
JHT10_01985	COG0189	ligase activity
JHT10_01995	COG1166	arginine decarboxylase activity
JHT10_02000	COG0010	Belongs to the arginase family
JHT10_02005	COG2814	Major facilitator Superfamily
JHT10_02010	COG1770	oligopeptidase
JHT10_02025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JHT10_02030	COG1121	(ABC) transporter
JHT10_02035	COG0803	Belongs to the bacterial solute-binding protein 9 family
JHT10_02075	COG0848	biopolymer transport protein
JHT10_02080	COG0811	peptide transport
JHT10_02085	COG0811	peptide transport
JHT10_02105	COG0745	RESPONSE REGULATOR receiver
JHT10_02110	COG0039	L-malate dehydrogenase activity
JHT10_02115	COG0584	glycerophosphoryl diester phosphodiesterase
JHT10_02125	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHT10_02180	COG1901	pseudouridine methyltransferase
JHT10_02185	COG0312	modulator of DNA gyrase
JHT10_02190	COG0312	modulator of DNA gyrase
JHT10_02195	COG0351	phosphomethylpyrimidine kinase
JHT10_02200	COG1116	anion transmembrane transporter activity
JHT10_02205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JHT10_02210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JHT10_02215	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JHT10_02220	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JHT10_02225	COG0352	thiamine-phosphate diphosphorylase activity
JHT10_02235	COG0243	molybdopterin cofactor binding
JHT10_02240	COG3005	denitrification pathway
JHT10_02250	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_02265	COG0456	acetyltransferase
JHT10_02285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHT10_02290	COG1929	Belongs to the glycerate kinase type-1 family
JHT10_02295	COG2610	gluconate transmembrane transporter activity
JHT10_02300	COG3835	regulator
JHT10_02325	COG0546	phosphoglycolate phosphatase activity
JHT10_02340	COG0583	DNA-binding transcription factor activity
JHT10_02350	COG0583	DNA-binding transcription factor activity
JHT10_02360	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JHT10_02365	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
JHT10_02365	COG3408	Glycogen debranching enzyme
JHT10_02395	COG3047	cAMP biosynthetic process
JHT10_02400	COG1357	PFAM Pentapeptide repeats (8 copies)
JHT10_02430	COG2375	cellular response to nickel ion
JHT10_02435	COG0823	Involved in the tonB-independent uptake of proteins
JHT10_02440	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHT10_02460	COG0800	Aldolase
JHT10_02465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHT10_02480	COG1917	Cupin 2, conserved barrel domain protein
JHT10_02490	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_02495	COG1414	Transcriptional regulator
JHT10_02510	COG0583	DNA-binding transcription factor activity
JHT10_02515	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JHT10_02520	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JHT10_02535	COG2199	diguanylate cyclase activity
JHT10_02545	COG0561	phosphatase activity
JHT10_02550	COG0583	DNA-binding transcription factor activity
JHT10_02565	COG0564	pseudouridine synthase activity
JHT10_02570	COG0534	Mate efflux family protein
JHT10_02575	COG5001	Diguanylate cyclase
JHT10_02585	COG3123	guanosine phosphorylase activity
JHT10_02625	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHT10_02635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JHT10_02640	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JHT10_02650	COG2259	Doxx family
JHT10_02655	COG1741	Belongs to the pirin family
JHT10_02675	COG0363	glucosamine-6-phosphate deaminase activity
JHT10_02685	COG0786	glutamate:sodium symporter activity
JHT10_02690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHT10_02695	COG1131	(ABC) transporter
JHT10_02705	COG0786	glutamate:sodium symporter activity
JHT10_02730	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JHT10_02740	COG3279	Response regulator of the LytR AlgR family
JHT10_02745	COG3275	phosphorelay sensor kinase activity
JHT10_02775	COG0772	Belongs to the SEDS family
JHT10_02780	COG0217	transcriptional regulatory protein
JHT10_02800	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JHT10_02800	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
JHT10_02810	COG0444	Belongs to the ABC transporter superfamily
JHT10_02815	COG4608	Belongs to the ABC transporter superfamily
JHT10_02840	COG1444	tRNA N-acetyltransferase activity
JHT10_02860	COG3340	Belongs to the peptidase S51 family
JHT10_02865	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JHT10_02870	COG1263	PTS System
JHT10_02870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHT10_02875	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JHT10_02935	COG0259	pyridoxamine-phosphate oxidase activity
JHT10_02960	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHT10_03005	COG1132	(ABC) transporter
JHT10_03015	COG2207	Transcriptional regulator
JHT10_03030	COG0513	Belongs to the DEAD box helicase family
JHT10_03035	COG2258	MOSC domain
JHT10_03050	COG1486	melibiose metabolic process
JHT10_03055	COG0583	DNA-binding transcription factor activity
JHT10_03070	COG1595	DNA-templated transcription, initiation
JHT10_03095	COG3634	alkyl hydroperoxide reductase activity
JHT10_03105	COG1846	Transcriptional regulator
JHT10_03110	COG1764	response to oxidative stress
JHT10_03135	COG2160	L-arabinose isomerase activity
JHT10_03145	COG1069	ribulokinase activity
JHT10_03150	COG1879	ABC-type sugar transport system periplasmic component
JHT10_03155	COG1129	ABC transporter
JHT10_03160	COG1172	Belongs to the binding-protein-dependent transport system permease family
JHT10_03165	COG0826	peptidase U32
JHT10_03190	COG1653	transport
JHT10_03195	COG0019	diaminopimelate decarboxylase activity
JHT10_03200	COG4264	IucA IucC family
JHT10_03225	COG4772	TonB-dependent receptor
JHT10_03230	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JHT10_03235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHT10_03240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHT10_03245	COG1120	ATPase activity
JHT10_03250	COG0840	transmembrane signaling receptor activity
JHT10_03255	COG0612	Peptidase, M16
JHT10_03265	COG0739	heme binding
JHT10_03275	COG2814	Major facilitator Superfamily
JHT10_03290	COG4580	involved in the transport of maltose and maltodextrins
JHT10_03310	COG2356	endonuclease I
JHT10_03330	COG1982	Orn Lys Arg decarboxylase major
JHT10_03335	COG0531	amino acid
JHT10_03345	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JHT10_03355	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JHT10_03360	COG1162	GTPase activity
JHT10_03365	COG1263	PTS System
JHT10_03365	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHT10_03375	COG1999	signal sequence binding
JHT10_03390	COG2909	trisaccharide binding
JHT10_03395	COG0058	SHG alpha-glucan phosphorylase activity
JHT10_03400	COG1640	4-alpha-glucanotransferase
JHT10_03405	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JHT10_03410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JHT10_03415	COG0366	Alpha amylase catalytic
JHT10_03425	COG3366	ferrous iron transmembrane transporter activity
JHT10_03430	COG0700	Nucleoside recognition
JHT10_03435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JHT10_03440	COG3339	Conserved Protein
JHT10_03445	COG1301	dicarboxylic acid transport
JHT10_03455	COG0583	DNA-binding transcription factor activity
JHT10_03470	COG0489	protein tyrosine kinase activity
JHT10_03470	COG3206	protein involved in exopolysaccharide biosynthesis
JHT10_03490	COG2095	MarC family integral membrane protein
JHT10_03495	COG4667	esterase of the alpha-beta hydrolase superfamily
JHT10_03500	COG3397	chitin binding
JHT10_03505	COG1054	Belongs to the UPF0176 family
JHT10_03520	COG1686	Belongs to the peptidase S11 family
JHT10_03545	COG0583	DNA-binding transcription factor activity
JHT10_03550	COG4628	conserved protein (DUF2132)
JHT10_03560	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JHT10_03570	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JHT10_03575	COG0628	permease
JHT10_03615	COG2814	Major facilitator Superfamily
JHT10_03625	COG0454	-acetyltransferase
JHT10_03635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JHT10_03640	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHT10_03645	COG1882	Formate acetyltransferase
JHT10_03675	COG1360	Flagellar Motor Protein
JHT10_03680	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JHT10_03685	COG1191	sigma factor activity
JHT10_03690	COG1580	Controls the rotational direction of flagella during chemotaxis
JHT10_03705	COG1516	flagellar protein fliS
JHT10_03710	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JHT10_03720	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_03735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JHT10_03745	COG1987	bacterial-type flagellum assembly
JHT10_03825	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JHT10_03845	COG0346	lactoylglutathione lyase activity
JHT10_03870	COG0745	RESPONSE REGULATOR receiver
JHT10_03890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_03900	COG0156	8-amino-7-oxononanoate synthase activity
JHT10_03905	COG1063	alcohol dehydrogenase
JHT10_03940	COG0668	transmembrane transport
JHT10_03950	COG1304	FMN binding
JHT10_03955	COG1620	l-lactate permease
JHT10_03960	COG0583	DNA-binding transcription factor activity
JHT10_03965	COG1505	serine-type exopeptidase activity
JHT10_03970	COG4172	Belongs to the ABC transporter superfamily
JHT10_03980	COG1067	ATP-dependent peptidase activity
JHT10_04005	COG1247	-acetyltransferase
JHT10_04010	COG0437	4 iron, 4 sulfur cluster binding
JHT10_04015	COG0348	domain, Protein
JHT10_04030	COG1122	ATPase activity
JHT10_04035	COG4720	Psort location CytoplasmicMembrane, score
JHT10_04040	COG1566	PFAM secretion protein HlyD family protein
JHT10_04050	COG3706	GGDEF domain
JHT10_04065	COG0813	purine-nucleoside phosphorylase activity
JHT10_04070	COG3272	Protein of unknown function (DUF1722)
JHT10_04075	COG0789	Transcriptional regulator
JHT10_04080	COG0415	Belongs to the DNA photolyase family
JHT10_04085	COG1376	ErfK ybiS ycfS ynhG family protein
JHT10_04085	COG1388	LysM domain
JHT10_04095	COG0513	Belongs to the DEAD box helicase family
JHT10_04100	COG1770	oligopeptidase
JHT10_04105	COG4771	TonB-dependent receptor
JHT10_04135	COG0573	inorganic phosphate transmembrane transporter activity
JHT10_04140	COG0581	inorganic phosphate transmembrane transporter activity
JHT10_04145	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JHT10_04160	COG2304	oxidoreductase activity
JHT10_04180	COG0714	Associated with various cellular activities
JHT10_04185	COG0840	transmembrane signaling receptor activity
JHT10_04195	COG2197	response regulator
JHT10_04245	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JHT10_04250	COG1120	ATPase activity
JHT10_04255	COG4774	siderophore transport
JHT10_04260	COG1132	(ABC) transporter
JHT10_04265	COG2205	protein histidine kinase activity
JHT10_04265	COG2205	protein histidine kinase activity
JHT10_04275	COG0569	domain protein
JHT10_04280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHT10_04290	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
JHT10_04295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHT10_04310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_04310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_04310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_04315	COG2207	Transcriptional regulator
JHT10_04325	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_04330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_04335	COG2084	Dehydrogenase
JHT10_04340	COG0753	catalase activity
JHT10_04350	COG2130	NADP-dependent
JHT10_04355	COG1309	transcriptional regulator
JHT10_04360	COG3097	Belongs to the UPF0267 family
JHT10_04415	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JHT10_04420	COG3842	ATPase activity
JHT10_04430	COG1175	transmembrane transport
JHT10_04435	COG3833	ABC-type maltose transport systems, permease component
JHT10_04460	COG2199	diguanylate cyclase activity
JHT10_04460	COG2200	EAL domain
JHT10_04460	COG2202	Pas domain
JHT10_04565	COG4789	Type iii secretion
JHT10_04570	COG4792	protein secretion
JHT10_04600	COG3710	Transcriptional regulator
JHT10_04610	COG4790	Type iii secretion
JHT10_04700	COG2916	Histone family protein nucleoid-structuring protein H-NS
JHT10_04720	COG2207	Transcriptional regulator
JHT10_04735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHT10_04745	COG0747	negative chemotaxis
JHT10_04765	COG0804	urea catabolic process
JHT10_04850	COG0183	Belongs to the thiolase family
JHT10_04865	COG3246	L-lysine catabolic process to acetate
JHT10_04875	COG3746	phosphate-selective porin O and P
JHT10_04890	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_04910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JHT10_04915	COG0494	nUDIX hydrolase
JHT10_04920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JHT10_04930	COG0625	glutathione transferase activity
JHT10_04935	COG1686	Belongs to the peptidase S11 family
JHT10_04950	COG0678	peroxiredoxin activity
JHT10_04950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JHT10_04955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JHT10_04965	COG1278	Cold shock
JHT10_04975	COG4667	esterase of the alpha-beta hydrolase superfamily
JHT10_04985	COG1846	Transcriptional regulator
JHT10_05000	COG2814	Major facilitator Superfamily
JHT10_05010	COG0673	inositol 2-dehydrogenase activity
JHT10_05015	COG2194	sulfuric ester hydrolase activity
JHT10_05020	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JHT10_05030	COG2205	protein histidine kinase activity
JHT10_05035	COG0745	RESPONSE REGULATOR receiver
JHT10_05040	COG4221	oxidoreductase activity
JHT10_05055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHT10_05075	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JHT10_05085	COG2814	Major facilitator Superfamily
JHT10_05095	COG1418	mRNA catabolic process
JHT10_05105	COG0402	S-adenosylhomocysteine deaminase activity
JHT10_05110	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JHT10_05115	COG2239	Acts as a magnesium transporter
JHT10_05120	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JHT10_05135	COG0531	amino acid
JHT10_05140	COG1522	sequence-specific DNA binding
JHT10_05165	COG2205	protein histidine kinase activity
JHT10_05165	COG5002	protein histidine kinase activity
JHT10_05165	COG0784	Response regulator, receiver
JHT10_05170	COG0673	inositol 2-dehydrogenase activity
JHT10_05175	COG0534	Mate efflux family protein
JHT10_05180	COG2926	Belongs to the UPF0265 family
JHT10_05190	COG3132	Protein of unknown function, DUF480
JHT10_05195	COG2827	Endonuclease containing a URI domain
JHT10_05200	COG1879	ABC-type sugar transport system periplasmic component
JHT10_05205	COG0784	Response regulator, receiver
JHT10_05205	COG2205	protein histidine kinase activity
JHT10_05215	COG1566	PFAM secretion protein HlyD family protein
JHT10_05235	COG1522	sequence-specific DNA binding
JHT10_05260	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHT10_05265	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHT10_05285	COG0183	Belongs to the thiolase family
JHT10_05305	COG3005	denitrification pathway
JHT10_05315	COG0243	molybdopterin cofactor binding
JHT10_05325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JHT10_05330	COG3850	Histidine kinase
JHT10_05335	COG2197	response regulator
JHT10_05350	COG2195	Cleaves the N-terminal amino acid of tripeptides
JHT10_05370	COG0840	transmembrane signaling receptor activity
JHT10_05380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHT10_05390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JHT10_05395	COG2814	Major facilitator Superfamily
JHT10_05400	COG0840	transmembrane signaling receptor activity
JHT10_05405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JHT10_05410	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JHT10_05430	COG2897	thiosulfate sulfurtransferase activity
JHT10_05450	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JHT10_05460	COG0302	gtp cyclohydrolase
JHT10_05465	COG1914	H( )-stimulated, divalent metal cation uptake system
JHT10_05475	COG0038	chloride channel
JHT10_05490	COG4989	oxidoreductase activity
JHT10_05505	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JHT10_05505	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JHT10_05510	COG0516	GMP reductase activity
JHT10_05515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JHT10_05580	COG3474	cytochrome
JHT10_05590	COG0789	Transcriptional regulator
JHT10_05595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JHT10_05600	COG0384	phenazine biosynthesis protein PhzF
JHT10_05610	COG1294	oxidase, subunit
JHT10_05615	COG1271	oxidase subunit
JHT10_05620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHT10_05625	COG0110	maltose O-acetyltransferase activity
JHT10_05630	COG3264	Mechanosensitive ion channel
JHT10_05630	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JHT10_05645	COG3437	response regulator, receiver
JHT10_05645	COG4999	Histidine kinase
JHT10_05645	COG2205	protein histidine kinase activity
JHT10_05645	COG3850	Histidine kinase
JHT10_05655	COG4770	biotin carboxylase activity
JHT10_05665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JHT10_05670	COG1960	acyl-CoA dehydrogenase activity
JHT10_05680	COG0183	Belongs to the thiolase family
JHT10_05690	COG1960	acyl-CoA dehydrogenase activity
JHT10_05695	COG1024	Enoyl-CoA hydratase
JHT10_05715	COG3706	GGDEF domain
JHT10_05720	COG1309	transcriptional regulator
JHT10_05725	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_05740	COG4176	ABC-type proline glycine betaine transport system permease component
JHT10_05745	COG4175	Glycine betaine
JHT10_05745	COG0517	IMP dehydrogenase activity
JHT10_05760	COG0330	HflC and HflK could
JHT10_05770	COG3300	MHYT domain
JHT10_05770	COG5001	Diguanylate cyclase
JHT10_05780	COG0784	Response regulator, receiver
JHT10_05780	COG2205	protein histidine kinase activity
JHT10_05835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JHT10_05840	COG5001	Diguanylate cyclase
JHT10_05845	COG1869	D-ribose catabolic process
JHT10_05850	COG1129	ABC transporter
JHT10_05855	COG1172	Belongs to the binding-protein-dependent transport system permease family
JHT10_05860	COG1879	ABC-type sugar transport system periplasmic component
JHT10_05865	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHT10_05870	COG1609	Transcriptional regulator
JHT10_05885	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JHT10_05900	COG0745	RESPONSE REGULATOR receiver
JHT10_05915	COG1785	Belongs to the alkaline phosphatase family
JHT10_05940	COG0814	amino acid
JHT10_05950	COG0243	molybdopterin cofactor binding
JHT10_05970	COG3707	response regulator
JHT10_05975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JHT10_05980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JHT10_05985	COG1116	anion transmembrane transporter activity
JHT10_05990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JHT10_05990	COG2146	nitrite reductase [NAD(P)H] activity
JHT10_06045	COG0515	serine threonine protein kinase
JHT10_06045	COG2815	serine threonine protein kinase
JHT10_06080	COG0631	protein serine/threonine phosphatase activity
JHT10_06150	COG0420	3'-5' exonuclease activity
JHT10_06155	COG0419	ATPase involved in DNA repair
JHT10_06175	COG3040	lipid binding
JHT10_06185	COG2814	Major facilitator Superfamily
JHT10_06195	COG1288	antiporter activity
JHT10_06205	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
JHT10_06220	COG2425	protein containing a von Willebrand factor type A (vWA) domain
JHT10_06235	COG0583	DNA-binding transcription factor activity
JHT10_06240	COG0277	FAD linked oxidase domain protein
JHT10_06255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHT10_06295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHT10_06295	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JHT10_06330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHT10_06335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JHT10_06345	COG2116	formate transmembrane transporter activity
JHT10_06365	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JHT10_06395	COG0534	Mate efflux family protein
JHT10_06400	COG0745	RESPONSE REGULATOR receiver
JHT10_06400	COG3292	Two component regulator propeller
JHT10_06400	COG2205	protein histidine kinase activity
JHT10_06410	COG3118	belongs to the thioredoxin family
JHT10_06415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JHT10_06440	COG2271	Major facilitator Superfamily
JHT10_06445	COG3851	Histidine kinase
JHT10_06450	COG2197	response regulator
JHT10_06460	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JHT10_06465	COG0583	DNA-binding transcription factor activity
JHT10_06470	COG0243	molybdopterin cofactor binding
JHT10_06500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_06515	COG1328	CTP reductase activity
JHT10_06520	COG0602	queuosine metabolic process
JHT10_06525	COG0534	Mate efflux family protein
JHT10_06540	COG4067	protein conserved in archaea
JHT10_06540	COG0189	ligase activity
JHT10_06550	COG3111	PFAM Bacterial OB fold (BOF) protein
JHT10_06555	COG1492	cobalamin metabolic process
JHT10_06560	COG0725	ABC transporter, periplasmic molybdate-binding protein
JHT10_06565	COG4149	molybdate abc transporter
JHT10_06570	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JHT10_06580	COG2203	Gaf domain
JHT10_06580	COG3706	GGDEF domain
JHT10_06580	COG4251	negative regulation of phosphorylation
JHT10_06580	COG5001	Diguanylate cyclase
JHT10_06605	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JHT10_06610	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JHT10_06635	COG3140	Belongs to the UPF0181 family
JHT10_06640	COG0589	response to stress
JHT10_06650	COG0583	DNA-binding transcription factor activity
JHT10_06665	COG0023	Translation Initiation Factor
JHT10_06675	COG1181	Belongs to the D-alanine--D-alanine ligase family
JHT10_06685	COG0045	succinate-CoA ligase (ADP-forming) activity
JHT10_06685	COG1042	CoA-binding domain protein
JHT10_06685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHT10_06690	COG0583	DNA-binding transcription factor activity
JHT10_06695	COG1629	transport
JHT10_06695	COG4771	TonB-dependent receptor
JHT10_06700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JHT10_06705	COG5001	Diguanylate cyclase
JHT10_06705	COG3447	MASE1 domain protein
JHT10_06705	COG5002	protein histidine kinase activity
JHT10_06710	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JHT10_06715	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JHT10_06720	COG1984	allophanate hydrolase subunit 2
JHT10_06730	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JHT10_06735	COG4181	ATPase activity
JHT10_06745	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JHT10_06750	COG3300	MHYT domain
JHT10_06750	COG5001	Diguanylate cyclase
JHT10_06760	COG0484	heat shock protein binding
JHT10_06785	COG4533	DNA binding
JHT10_06795	COG2050	protein possibly involved in aromatic compounds catabolism
JHT10_06810	COG2067	long-chain fatty acid transport protein
JHT10_06815	COG2267	carboxylic ester hydrolase activity
JHT10_06830	COG0861	Integral membrane protein TerC family
JHT10_06835	COG0737	Belongs to the 5'-nucleotidase family
JHT10_06840	COG3593	DNA synthesis involved in DNA repair
JHT10_06850	COG0583	DNA-binding transcription factor activity
JHT10_06855	COG2116	formate transmembrane transporter activity
JHT10_06860	COG2353	YceI-like domain
JHT10_06865	COG3038	cytochrome b561
JHT10_06880	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JHT10_06885	COG0513	Belongs to the DEAD box helicase family
JHT10_06890	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
JHT10_06900	COG0546	phosphoglycolate phosphatase activity
JHT10_06905	COG0784	Response regulator, receiver
JHT10_06905	COG3437	response regulator, receiver
JHT10_06920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHT10_06925	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JHT10_06930	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JHT10_06940	COG2207	Transcriptional regulator
JHT10_06945	COG1979	alcohol dehydrogenase
JHT10_06970	COG2271	Major facilitator Superfamily
JHT10_06975	COG0469	pyruvate kinase activity
JHT10_06980	COG1126	abc transporter atp-binding protein
JHT10_06985	COG0765	amino acid transport
JHT10_06990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_06995	COG0765	amino acid transport
JHT10_07000	COG2200	EAL domain
JHT10_07000	COG2203	Gaf domain
JHT10_07000	COG2199	diguanylate cyclase activity
JHT10_07015	COG1609	Transcriptional regulator
JHT10_07020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_07020	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_07025	COG1105	Belongs to the carbohydrate kinase PfkB family
JHT10_07030	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JHT10_07030	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_07030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHT10_07070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JHT10_07075	COG0509	glycine decarboxylation via glycine cleavage system
JHT10_07080	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JHT10_07080	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JHT10_07085	COG0653	protein targeting
JHT10_07170	COG3344	reverse transcriptase
JHT10_07200	COG4735	regulation of single-species biofilm formation
JHT10_07245	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JHT10_07250	COG0583	DNA-binding transcription factor activity
JHT10_07255	COG2176	DNA-directed DNA polymerase activity
JHT10_07300	COG0242	peptide deformylase activity
JHT10_07330	COG2239	Acts as a magnesium transporter
JHT10_07350	COG0346	lactoylglutathione lyase activity
JHT10_07355	COG1902	pentaerythritol trinitrate reductase activity
JHT10_07375	COG5642	Protein of unknown function (DUF2384)
JHT10_07380	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JHT10_07395	COG4565	transcriptional regulatory protein
JHT10_07400	COG3290	protein histidine kinase activity
JHT10_07405	COG0471	metal ion transport
JHT10_07435	COG2076	Multidrug Resistance protein
JHT10_07450	COG0671	phosphoesterase, PA-phosphatase related
JHT10_07460	COG2962	Rard protein
JHT10_07475	COG0835	chemotaxis
JHT10_07475	COG0784	Response regulator, receiver
JHT10_07500	COG2197	response regulator
JHT10_07510	COG3706	GGDEF domain
JHT10_07515	COG2197	response regulator
JHT10_07520	COG3300	MHYT domain
JHT10_07520	COG5001	Diguanylate cyclase
JHT10_07540	COG0583	DNA-binding transcription factor activity
JHT10_07600	COG4964	Belongs to the GSP D family
JHT10_07625	COG2207	Transcriptional regulator
JHT10_07645	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JHT10_07665	COG1214	PFAM Peptidase M22, glycoprotease
JHT10_07665	COG0456	acetyltransferase
JHT10_07675	COG3069	C4-dicarboxylate transmembrane transporter activity
JHT10_07680	COG1704	LemA family
JHT10_07685	COG0501	Belongs to the peptidase M48B family
JHT10_07710	COG0641	radical SAM
JHT10_07725	COG3111	PFAM Bacterial OB fold (BOF) protein
JHT10_07730	COG1597	lipid kinase activity
JHT10_07735	COG0583	DNA-binding transcription factor activity
JHT10_07740	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHT10_07770	COG0714	Associated with various cellular activities
JHT10_07775	COG0641	radical SAM
JHT10_07780	COG3119	arylsulfatase activity
JHT10_07795	COG3119	arylsulfatase activity
JHT10_07800	COG3119	arylsulfatase activity
JHT10_07805	COG0745	RESPONSE REGULATOR receiver
JHT10_07820	COG0784	Response regulator, receiver
JHT10_07820	COG2198	Histidine kinase
JHT10_07820	COG2205	protein histidine kinase activity
JHT10_07825	COG1879	ABC-type sugar transport system periplasmic component
JHT10_07830	COG1803	Methylglyoxal synthase
JHT10_07835	COG0210	DNA helicase
JHT10_07840	COG1289	transmembrane transporter activity
JHT10_07870	COG4771	TonB-dependent receptor
JHT10_07870	COG1629	transport
JHT10_07875	COG2207	Transcriptional regulator
JHT10_07880	COG0789	Transcriptional regulator
JHT10_07885	COG4604	ABC transporter, ATP-binding protein
JHT10_07890	COG4605	iron ion homeostasis
JHT10_07895	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHT10_07900	COG4607	ABC-type enterochelin transport system periplasmic component
JHT10_07920	COG2847	Copper chaperone PCu(A)C
JHT10_07925	COG0443	Heat shock 70 kDa protein
JHT10_07960	COG0625	glutathione transferase activity
JHT10_07975	COG4160	amino acid transport
JHT10_07980	COG4215	(ABC) transporter
JHT10_07985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_07990	COG1126	abc transporter atp-binding protein
JHT10_08000	COG1902	pentaerythritol trinitrate reductase activity
JHT10_08005	COG0109	protoheme IX farnesyltransferase activity
JHT10_08010	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JHT10_08015	COG1845	cytochrome c oxidase, subunit III
JHT10_08020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JHT10_08025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JHT10_08030	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_08040	COG1024	Enoyl-CoA hydratase
JHT10_08045	COG1024	Enoyl-CoA hydratase
JHT10_08060	COG0183	Belongs to the thiolase family
JHT10_08070	COG1960	acyl-CoA dehydrogenase activity
JHT10_08075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JHT10_08080	COG1024	Enoyl-CoA hydratase
JHT10_08090	COG5413	integral membrane protein
JHT10_08105	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHT10_08110	COG5001	Diguanylate cyclase
JHT10_08115	COG0513	Belongs to the DEAD box helicase family
JHT10_08120	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
JHT10_08135	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JHT10_08140	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JHT10_08145	COG0592	DNA-directed DNA polymerase activity
JHT10_08150	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JHT10_08155	COG0187	DNA topoisomerase II activity
JHT10_08165	COG0071	Belongs to the small heat shock protein (HSP20) family
JHT10_08170	COG3977	Valine--pyruvate aminotransferase
JHT10_08175	COG0366	Alpha amylase catalytic
JHT10_08180	COG0751	glycine-tRNA ligase activity
JHT10_08185	COG0752	glycyl-tRNA synthetase alpha subunit
JHT10_08190	COG2119	membrane
JHT10_08200	COG0425	Belongs to the sulfur carrier protein TusA family
JHT10_08215	COG0604	alcohol dehydrogenase
JHT10_08220	COG0183	Belongs to the thiolase family
JHT10_08225	COG1024	Enoyl-CoA hydratase
JHT10_08225	COG1250	3-hydroxyacyl-CoA dehydrogenase
JHT10_08230	COG1739	Uncharacterized protein family UPF0029
JHT10_08235	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHT10_08270	COG0583	DNA-binding transcription factor activity
JHT10_08275	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JHT10_08280	COG2960	long-chain fatty acid transporting porin activity
JHT10_08285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_08290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_08340	COG4172	Belongs to the ABC transporter superfamily
JHT10_08345	COG0747	negative chemotaxis
JHT10_08350	COG0601	transmembrane transport
JHT10_08355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHT10_08390	COG1609	Transcriptional regulator
JHT10_08395	COG0583	DNA-binding transcription factor activity
JHT10_08410	COG0129	dihydroxy-acid dehydratase activity
JHT10_08415	COG3265	gluconokinase activity
JHT10_08420	COG2610	gluconate transmembrane transporter activity
JHT10_08425	COG0800	Aldolase
JHT10_08430	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JHT10_08435	COG0583	DNA-binding transcription factor activity
JHT10_08440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JHT10_08445	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JHT10_08450	COG0339	signal peptide processing
JHT10_08455	COG1522	sequence-specific DNA binding
JHT10_08460	COG5001	Diguanylate cyclase
JHT10_08460	COG5002	protein histidine kinase activity
JHT10_08465	COG0742	ribosomal rna small subunit methyltransferase
JHT10_08480	COG0589	response to stress
JHT10_08485	COG1528	Iron-storage protein
JHT10_08495	COG2081	HI0933 family
JHT10_08555	COG0628	permease
JHT10_08570	COG1322	Protein conserved in bacteria
JHT10_08575	COG2226	methyltransferase
JHT10_08580	COG3165	ubiquinone biosynthetic process from chorismate
JHT10_08585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JHT10_08590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JHT10_08595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JHT10_08600	COG0805	protein transport
JHT10_08605	COG0084	hydrolase, TatD family'
JHT10_08625	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHT10_08625	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHT10_08630	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JHT10_08660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JHT10_08670	COG2204	response regulator
JHT10_08675	COG3852	Histidine kinase
JHT10_08685	COG0174	glutamine synthetase
JHT10_08690	COG1217	gtp-binding protein TYPA
JHT10_08705	COG1295	ribonuclease BN
JHT10_08710	COG1490	D-aminoacyl-tRNA deacylase activity
JHT10_08715	COG0456	acetyltransferase
JHT10_08725	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JHT10_08730	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JHT10_08735	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JHT10_08740	COG3031	protein transport across the cell outer membrane
JHT10_08750	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHT10_08755	COG1459	type II secretion system
JHT10_08760	COG2165	general secretion pathway protein
JHT10_08765	COG2165	general secretion pathway protein
JHT10_08770	COG2165	general secretion pathway protein
JHT10_08775	COG4795	General secretion pathway protein
JHT10_08780	COG3156	type II secretion system protein K
JHT10_08785	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JHT10_08790	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JHT10_08800	COG1218	3'(2'),5'-bisphosphate nucleotidase
JHT10_08805	COG0494	nUDIX hydrolase
JHT10_08810	COG0316	Belongs to the HesB IscA family
JHT10_08810	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JHT10_08815	COG1040	competence protein
JHT10_08820	COG0596	Alpha beta hydrolase
JHT10_08830	COG2183	response to ionizing radiation
JHT10_08840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHT10_08860	COG2233	PERMEase
JHT10_08865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JHT10_08870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHT10_08875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JHT10_08880	COG1758	RNA polymerase activity
JHT10_08885	COG0194	GDP metabolic process
JHT10_08900	COG0848	biopolymer transport protein
JHT10_08905	COG0811	peptide transport
JHT10_08925	COG4174	ABC transporter (Permease)
JHT10_08930	COG4239	(ABC) transporter, permease
JHT10_08935	COG0747	negative chemotaxis
JHT10_08940	COG0444	Belongs to the ABC transporter superfamily
JHT10_08945	COG4608	Belongs to the ABC transporter superfamily
JHT10_08955	COG5001	Diguanylate cyclase
JHT10_09010	COG2246	polysaccharide biosynthetic process
JHT10_09025	COG1561	YicC-like family, N-terminal region
JHT10_09030	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JHT10_09035	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JHT10_09040	COG1560	Kdo2-lipid A biosynthetic process
JHT10_09045	COG1309	transcriptional regulator
JHT10_09050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JHT10_09060	COG2003	Belongs to the UPF0758 family
JHT10_09065	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JHT10_09080	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JHT10_09085	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JHT10_09100	COG0463	Glycosyl transferase, family 2
JHT10_09105	COG0859	PFAM glycosyl transferase family 9
JHT10_09110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JHT10_09115	COG3642	lipopolysaccharide core region biosynthetic process
JHT10_09135	COG0110	maltose O-acetyltransferase activity
JHT10_09140	COG2030	dehydratase
JHT10_09160	COG0297	glycogen (starch) synthase activity
JHT10_09160	COG0438	transferase activity, transferring glycosyl groups
JHT10_09170	COG1519	Transferase
JHT10_09175	COG0859	PFAM glycosyl transferase family 9
JHT10_09180	COG1560	Kdo2-lipid A biosynthetic process
JHT10_09190	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHT10_09225	COG1086	Polysaccharide biosynthesis protein
JHT10_09230	COG1083	cytidylyl-transferase
JHT10_09240	COG2089	acid synthase
JHT10_09295	COG1482	cell wall glycoprotein biosynthetic process
JHT10_09310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JHT10_09325	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JHT10_09330	COG0149	triose-phosphate isomerase activity
JHT10_09355	COG1494	fructose-1,6-bisphosphatase
JHT10_09360	COG3074	FtsZ-dependent cytokinesis
JHT10_09365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JHT10_09370	COG1575	Belongs to the MenA family. Type 1 subfamily
JHT10_09375	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JHT10_09380	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JHT10_09390	COG1609	Transcriptional regulator
JHT10_09395	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JHT10_09400	COG0254	rRNA binding
JHT10_09410	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JHT10_09415	COG0088	Forms part of the polypeptide exit tunnel
JHT10_09425	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JHT10_09430	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JHT10_09435	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JHT10_09440	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JHT10_09450	COG0255	Belongs to the universal ribosomal protein uL29 family
JHT10_09455	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JHT10_09460	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JHT10_09465	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JHT10_09470	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JHT10_09475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JHT10_09480	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JHT10_09485	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JHT10_09500	COG1841	ribosomal large subunit assembly
JHT10_09505	COG0200	Binds to the 23S rRNA
JHT10_09510	COG0201	protein transport
JHT10_09515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JHT10_09520	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JHT10_09525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JHT10_09535	COG0202	RNA polymerase activity
JHT10_09540	COG0203	ribosomal protein L17
JHT10_09550	COG0545	Peptidyl-prolyl cis-trans isomerase
JHT10_09560	COG2153	protein acetylation
JHT10_09565	COG0513	Belongs to the DEAD box helicase family
JHT10_09575	COG0737	Belongs to the 5'-nucleotidase family
JHT10_09580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JHT10_09580	COG1648	precorrin-2 dehydrogenase activity
JHT10_09585	COG0175	sulfate reduction
JHT10_09590	COG2895	sulfate adenylyltransferase (ATP) activity
JHT10_09595	COG3273	potassium ion transport
JHT10_09595	COG0471	metal ion transport
JHT10_09600	COG0529	Catalyzes the synthesis of activated sulfate
JHT10_09620	COG1136	(ABC) transporter
JHT10_09635	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JHT10_09645	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHT10_09650	COG0729	surface antigen
JHT10_09655	COG2911	Protein conserved in bacteria
JHT10_09660	COG2105	PFAM AIG2 family protein
JHT10_09670	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JHT10_09675	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JHT10_09680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JHT10_09685	COG0163	prenyltransferase activity
JHT10_09690	COG4143	(ABC) transporter
JHT10_09695	COG1178	ABC-type Fe3 transport system permease component
JHT10_09700	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JHT10_09715	COG2358	TRAP transporter, solute receptor (TAXI family
JHT10_09725	COG0039	L-malate dehydrogenase activity
JHT10_09735	COG0142	geranyltranstransferase activity
JHT10_09740	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JHT10_09750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JHT10_09755	COG2966	Psort location CytoplasmicMembrane, score
JHT10_09770	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JHT10_09775	COG2967	ApaG domain
JHT10_09780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JHT10_09785	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JHT10_09790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JHT10_09795	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JHT10_09800	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JHT10_09810	COG0066	3-isopropylmalate dehydratase activity
JHT10_09815	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JHT10_09820	COG0473	3-isopropylmalate dehydrogenase activity
JHT10_09825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JHT10_09845	COG0583	DNA-binding transcription factor activity
JHT10_09850	COG1022	Amp-dependent synthetase and ligase
JHT10_09855	COG0028	Belongs to the TPP enzyme family
JHT10_09860	COG0440	acetolactate synthase activity
JHT10_09875	COG0469	pyruvate kinase activity
JHT10_09880	COG1349	DNA-binding transcription factor activity
JHT10_09885	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JHT10_09900	COG5002	protein histidine kinase activity
JHT10_09905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHT10_09910	COG3722	fumarate hydratase activity
JHT10_09915	COG0246	Mannitol dehydrogenase
JHT10_09920	COG2213	PTS system mannitol-specific
JHT10_09920	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_09950	COG1464	Belongs to the NlpA lipoprotein family
JHT10_09965	COG0358	DNA primase activity
JHT10_09970	COG1610	YqeY-like protein
JHT10_09975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JHT10_09980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JHT10_09985	COG0596	Alpha beta hydrolase
JHT10_09990	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JHT10_09995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JHT10_10000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JHT10_10005	COG1968	undecaprenyl-diphosphatase activity
JHT10_10010	COG0617	tRNA 3'-terminal CCA addition
JHT10_10015	COG3267	Type II secretory pathway component ExeA
JHT10_10015	COG3409	Peptidoglycan-binding domain 1 protein
JHT10_10025	COG4991	sh3 domain protein
JHT10_10030	COG0306	phosphate transporter
JHT10_10035	COG1392	Phosphate transport regulator
JHT10_10040	COG3025	triphosphatase activity
JHT10_10055	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JHT10_10060	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JHT10_10060	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JHT10_10065	COG1538	Outer membrane efflux protein
JHT10_10070	COG0494	nUDIX hydrolase
JHT10_10075	COG3151	Protein conserved in bacteria
JHT10_10085	COG3150	esterase
JHT10_10095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JHT10_10100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JHT10_10110	COG3105	Protein conserved in bacteria
JHT10_10115	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JHT10_10120	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JHT10_10125	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JHT10_10130	COG0723	plastoquinol--plastocyanin reductase activity
JHT10_10135	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JHT10_10140	COG2857	Cytochrome c1
JHT10_10145	COG0625	glutathione transferase activity
JHT10_10150	COG2969	positive regulation of protein catabolic process
JHT10_10155	COG2823	Periplasmic or secreted lipoprotein
JHT10_10160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JHT10_10165	COG0792	nuclease activity
JHT10_10175	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JHT10_10185	COG0275	rRNA processing
JHT10_10190	COG3116	cell division
JHT10_10195	COG0768	penicillin binding
JHT10_10200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JHT10_10205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JHT10_10210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JHT10_10215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JHT10_10220	COG0772	Belongs to the SEDS family
JHT10_10225	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JHT10_10230	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JHT10_10235	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JHT10_10240	COG0849	cell division
JHT10_10245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JHT10_10250	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JHT10_10260	COG0653	protein targeting
JHT10_10265	COG0494	nUDIX hydrolase
JHT10_10270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JHT10_10275	COG0505	Belongs to the CarA family
JHT10_10280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JHT10_10290	COG0730	response to heat
JHT10_10295	COG0583	DNA-binding transcription factor activity
JHT10_10300	COG2860	membrane
JHT10_10305	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JHT10_10315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JHT10_10325	COG0493	'glutamate synthase
JHT10_10330	COG0070	glutamate synthase
JHT10_10330	COG0067	glutamate synthase
JHT10_10330	COG0069	glutamate synthase activity
JHT10_10340	COG0067	glutamate synthase
JHT10_10340	COG0069	glutamate synthase activity
JHT10_10340	COG0070	glutamate synthase
JHT10_10345	COG1242	4 iron, 4 sulfur cluster binding
JHT10_10350	COG4251	negative regulation of phosphorylation
JHT10_10350	COG5001	Diguanylate cyclase
JHT10_10350	COG3706	GGDEF domain
JHT10_10350	COG2203	Gaf domain
JHT10_10355	COG0784	Response regulator, receiver
JHT10_10355	COG2198	Histidine kinase
JHT10_10355	COG5002	protein histidine kinase activity
JHT10_10365	COG0745	RESPONSE REGULATOR receiver
JHT10_10375	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JHT10_10390	COG0083	homoserine kinase activity
JHT10_10395	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JHT10_10400	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
JHT10_10405	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JHT10_10410	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JHT10_10425	COG1115	amino acid carrier protein
JHT10_10430	COG3022	response to hydroperoxide
JHT10_10435	COG0513	Belongs to the DEAD box helicase family
JHT10_10440	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JHT10_10450	COG0716	FMN binding
JHT10_10455	COG4974	Belongs to the 'phage' integrase family
JHT10_10460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHT10_10465	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JHT10_10475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JHT10_10480	COG2204	response regulator
JHT10_10490	COG0667	Aldo Keto reductase
JHT10_10500	COG3066	DNA modification
JHT10_10505	COG0494	nUDIX hydrolase
JHT10_10515	COG0730	response to heat
JHT10_10520	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JHT10_10525	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JHT10_10535	COG1283	sodium-dependent phosphate transmembrane transporter activity
JHT10_10540	COG0583	DNA-binding transcription factor activity
JHT10_10545	COG0640	Transcriptional regulator
JHT10_10550	COG0268	Binds directly to 16S ribosomal RNA
JHT10_10555	COG0728	peptidoglycan biosynthetic process
JHT10_10560	COG0196	riboflavin kinase activity
JHT10_10565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JHT10_10570	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JHT10_10575	COG1047	Peptidyl-prolyl cis-trans
JHT10_10580	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JHT10_10585	COG3279	Response regulator of the LytR AlgR family
JHT10_10590	COG3275	phosphorelay sensor kinase activity
JHT10_10595	COG1966	Carbon starvation protein
JHT10_10610	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JHT10_10615	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JHT10_10620	COG1472	Belongs to the glycosyl hydrolase 3 family
JHT10_10625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JHT10_10630	COG1605	Chorismate mutase
JHT10_10630	COG0287	Prephenate dehydrogenase
JHT10_10635	COG0739	heme binding
JHT10_10645	COG0488	(ABC) transporter
JHT10_10655	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
JHT10_10660	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
JHT10_10665	COG1605	Chorismate mutase
JHT10_10665	COG0077	Prephenate dehydratase
JHT10_10670	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JHT10_10675	COG0741	lytic transglycosylase activity
JHT10_10680	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHT10_10685	COG0564	pseudouridine synthase activity
JHT10_10695	COG0542	response to heat
JHT10_10750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JHT10_10755	COG0826	peptidase U32
JHT10_10760	COG2974	May be involved in recombination
JHT10_10765	COG0745	RESPONSE REGULATOR receiver
JHT10_10770	COG5002	protein histidine kinase activity
JHT10_10780	COG0248	Ppx GppA phosphatase
JHT10_10785	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JHT10_10795	COG0581	inorganic phosphate transmembrane transporter activity
JHT10_10800	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JHT10_10805	COG0704	Plays a role in the regulation of phosphate uptake
JHT10_10815	COG3142	Participates in the control of copper homeostasis
JHT10_10820	COG0450	alkyl hydroperoxide reductase
JHT10_10825	COG0583	DNA-binding transcription factor activity
JHT10_10830	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JHT10_10840	COG0517	IMP dehydrogenase activity
JHT10_10850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JHT10_10855	COG0343	queuine tRNA-ribosyltransferase activity
JHT10_10860	COG1862	Preprotein translocase
JHT10_10865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHT10_10870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHT10_10875	COG0483	inositol monophosphate 1-phosphatase activity
JHT10_10890	COG1104	cysteine desulfurase activity
JHT10_10895	COG0822	iron-sulfur transferase activity
JHT10_10905	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JHT10_10910	COG0443	Heat shock 70 kDa protein
JHT10_10915	COG0633	Ferredoxin
JHT10_10920	COG2975	iron-sulfur cluster assembly
JHT10_10925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JHT10_10930	COG0105	UTP biosynthetic process
JHT10_10935	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JHT10_10945	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JHT10_10950	COG0124	histidyl-tRNA synthetase
JHT10_10955	COG2976	Protein conserved in bacteria
JHT10_10960	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHT10_10965	COG1160	GTP binding
JHT10_10980	COG1570	exodeoxyribonuclease VII activity
JHT10_10985	COG0516	GMP reductase activity
JHT10_10985	COG0517	IMP dehydrogenase activity
JHT10_10990	COG0519	Catalyzes the synthesis of GMP from XMP
JHT10_10990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JHT10_10995	COG1757	Na H antiporter
JHT10_11005	COG1584	GPR1 FUN34 yaaH family protein
JHT10_11045	COG2873	o-acetylhomoserine
JHT10_11050	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JHT10_11070	COG3153	acetyltransferase
JHT10_11070	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JHT10_11075	COG0583	DNA-binding transcription factor activity
JHT10_11135	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JHT10_11140	COG2867	negative regulation of translational initiation
JHT10_11145	COG2914	Belongs to the UPF0125 (RnfH) family
JHT10_11150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHT10_11155	COG0497	DNA recombination
JHT10_11165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JHT10_11170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JHT10_11180	COG0443	Heat shock 70 kDa protein
JHT10_11185	COG0484	heat shock protein binding
JHT10_11195	COG4969	Belongs to the N-Me-Phe pilin family
JHT10_11215	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JHT10_11225	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JHT10_11230	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JHT10_11230	COG0047	phosphoribosylformylglycinamidine synthase activity
JHT10_11255	COG2195	Cleaves the N-terminal amino acid of tripeptides
JHT10_11260	COG2252	PERMEase
JHT10_11265	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JHT10_11270	COG1073	alpha beta
JHT10_11280	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JHT10_11285	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JHT10_11290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JHT10_11295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHT10_11295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHT10_11315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JHT10_11320	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JHT10_11325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JHT10_11330	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JHT10_11335	COG0142	geranyltranstransferase activity
JHT10_11340	COG1722	exodeoxyribonuclease VII activity
JHT10_11345	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JHT10_11350	COG2885	chlorophyll binding
JHT10_11355	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHT10_11355	COG0301	tRNA thio-modification
JHT10_11360	COG0583	DNA-binding transcription factor activity
JHT10_11370	COG2363	Small membrane protein
JHT10_11375	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JHT10_11385	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHT10_11390	COG1611	Belongs to the LOG family
JHT10_11405	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JHT10_11405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JHT10_11415	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
JHT10_11420	COG1464	Belongs to the NlpA lipoprotein family
JHT10_11425	COG2011	ABC-type metal ion transport system permease component
JHT10_11430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JHT10_11435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JHT10_11445	COG1263	PTS System
JHT10_11445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHT10_11450	COG0366	Alpha amylase catalytic
JHT10_11465	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHT10_11470	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JHT10_11475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JHT10_11480	COG0321	lipoyl(octanoyl) transferase activity
JHT10_11485	COG2921	Belongs to the UPF0250 family
JHT10_11490	COG1686	Belongs to the peptidase S11 family
JHT10_11495	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JHT10_11500	COG0772	Belongs to the SEDS family
JHT10_11505	COG0768	penicillin binding
JHT10_11510	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JHT10_11515	COG0799	negative regulation of ribosome biogenesis
JHT10_11520	COG1466	dna polymerase III delta subunit
JHT10_11525	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
JHT10_11530	COG0495	leucyl-tRNA aminoacylation
JHT10_11535	COG2888	peptidyl-tyrosine sulfation
JHT10_11540	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JHT10_11545	COG4535	Mg2 and Co2 transporter CorC
JHT10_11550	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JHT10_11555	COG1702	phosphate starvation-inducible protein PhoH
JHT10_11560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JHT10_11565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JHT10_11680	COG0012	GTP binding
JHT10_11685	COG0193	aminoacyl-tRNA hydrolase activity
JHT10_11690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JHT10_11695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JHT10_11700	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JHT10_11705	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JHT10_11710	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JHT10_11715	COG2890	protein-(glutamine-N5) methyltransferase activity
JHT10_11720	COG3094	Invasion gene expression up-regulator, SirB
JHT10_11725	COG2912	Transglutaminase-like superfamily
JHT10_11730	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JHT10_11735	COG0737	Belongs to the 5'-nucleotidase family
JHT10_11745	COG1187	pseudouridine synthase activity
JHT10_11750	COG2840	Smr protein MutS2
JHT10_11785	COG2608	mercury ion transmembrane transporter activity
JHT10_11785	COG2217	Heavy metal translocating P-type atpase
JHT10_11795	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JHT10_11800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHT10_11850	COG0784	Response regulator, receiver
JHT10_11850	COG0835	chemotaxis
JHT10_11855	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JHT10_11860	COG1815	bacterial-type flagellum-dependent cell motility
JHT10_11865	COG1558	bacterial-type flagellum-dependent cell motility
JHT10_11875	COG1749	Flagellar hook protein flgE
JHT10_11880	COG4787	bacterial-type flagellum-dependent cell motility
JHT10_11890	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JHT10_11895	COG1706	bacterial-type flagellum-dependent cell motility
JHT10_11900	COG1705	Flagellar rod assembly protein muramidase FlgJ
JHT10_11900	COG3951	Flagellar rod assembly protein muramidase FlgJ
JHT10_11910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_11915	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_11920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_11925	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_11930	COG2190	(PTS) system
JHT10_11935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JHT10_11940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_11945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JHT10_11950	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
JHT10_11955	COG3115	cell septum assembly
JHT10_11960	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JHT10_11980	COG0330	HflC and HflK could
JHT10_11985	COG3118	belongs to the thioredoxin family
JHT10_11990	COG0300	oxidoreductase activity
JHT10_11995	COG1090	epimerase
JHT10_12020	COG0622	Phosphoesterase
JHT10_12040	COG3710	Transcriptional regulator
JHT10_12045	COG0326	Molecular chaperone. Has ATPase activity
JHT10_12050	COG0563	adenylate kinase activity
JHT10_12055	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JHT10_12060	COG3104	oligopeptide transport
JHT10_12065	COG0250	Participates in transcription elongation, termination and antitermination
JHT10_12070	COG0367	asparagine synthase
JHT10_12075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JHT10_12075	COG4651	solute:proton antiporter activity
JHT10_12080	COG1846	Transcriptional regulator
JHT10_12080	COG1940	carbohydrate kinase activity
JHT10_12085	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JHT10_12090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHT10_12090	COG1263	PTS System
JHT10_12095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHT10_12100	COG0735	belongs to the Fur family
JHT10_12110	COG0716	FMN binding
JHT10_12120	COG0596	Alpha beta hydrolase
JHT10_12125	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JHT10_12130	COG0033	Phosphoglucomutase
JHT10_12140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JHT10_12155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JHT10_12160	COG1053	succinate dehydrogenase
JHT10_12165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JHT10_12170	COG0567	Dehydrogenase, E1 component
JHT10_12175	COG0508	dehydrogenase complex catalyzes the overall conversion of
JHT10_12180	COG0045	succinate-CoA ligase (ADP-forming) activity
JHT10_12190	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JHT10_12195	COG1121	(ABC) transporter
JHT10_12200	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JHT10_12205	COG4977	sequence-specific DNA binding
JHT10_12210	COG1918	ferrous iron import across plasma membrane
JHT10_12230	COG0018	arginyl-trna synthetase
JHT10_12235	COG3102	Protein conserved in bacteria
JHT10_12240	COG0788	formyltetrahydrofolate deformylase activity
JHT10_12245	COG1199	ATP-dependent helicase activity
JHT10_12250	COG1214	PFAM Peptidase M22, glycoprotease
JHT10_12265	COG2267	carboxylic ester hydrolase activity
JHT10_12270	COG0318	PFAM AMP-dependent synthetase and ligase
JHT10_12275	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JHT10_12280	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JHT10_12285	COG2894	cell division
JHT10_12290	COG0850	regulation of cytokinetic process
JHT10_12295	COG3100	YcgL domain-containing protein
JHT10_12300	COG2951	lytic endotransglycosylase activity
JHT10_12305	COG0583	DNA-binding transcription factor activity
JHT10_12310	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHT10_12315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JHT10_12335	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_12345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JHT10_12370	COG2986	histidine ammonia-lyase
JHT10_12375	COG1216	Glycosyl transferase, family 2
JHT10_12380	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JHT10_12395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JHT10_12400	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JHT10_12435	COG1253	flavin adenine dinucleotide binding
JHT10_12440	COG0513	Belongs to the DEAD box helicase family
JHT10_12445	COG0569	domain protein
JHT10_12450	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHT10_12465	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JHT10_12470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JHT10_12475	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JHT10_12480	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JHT10_12490	COG2204	response regulator
JHT10_12505	COG0544	peptidyl-prolyl cis-trans isomerase activity
JHT10_12515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JHT10_12520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JHT10_12525	COG0776	regulation of translation
JHT10_12530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JHT10_12535	COG1555	photosystem II stabilization
JHT10_12550	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JHT10_12555	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
JHT10_12560	COG0436	Aminotransferase
JHT10_12565	COG1169	isochorismate synthase
JHT10_12575	COG0596	Alpha beta hydrolase
JHT10_12580	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JHT10_12600	COG2855	membrane
JHT10_12605	COG0477	Major facilitator Superfamily
JHT10_12650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_12655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_12680	COG1522	sequence-specific DNA binding
JHT10_12690	COG1946	Acyl-CoA thioesterase
JHT10_12695	COG3126	Type III secretion system lipoprotein chaperone (YscW)
JHT10_12710	COG2199	diguanylate cyclase activity
JHT10_12720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHT10_12725	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JHT10_12730	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JHT10_12735	COG0516	GMP reductase activity
JHT10_12735	COG0517	IMP dehydrogenase activity
JHT10_12760	COG0537	adenosine 5'-monophosphoramidase activity
JHT10_12785	COG3150	esterase
JHT10_12790	COG1252	NADH dehydrogenase
JHT10_12805	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JHT10_12815	COG4591	ABC-type transport system involved in lipoprotein release permease component
JHT10_12820	COG1136	(ABC) transporter
JHT10_12825	COG4591	ABC-type transport system involved in lipoprotein release permease component
JHT10_12835	COG2333	competence protein COMEC
JHT10_12835	COG0658	competence protein
JHT10_12840	COG1132	(ABC) transporter
JHT10_12845	COG1663	tetraacyldisaccharide 4'-kinase activity
JHT10_12855	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JHT10_12860	COG2719	SpoVR family
JHT10_12865	COG2718	Belongs to the UPF0229 family
JHT10_12870	COG2766	serine protein kinase
JHT10_12875	COG3013	Belongs to the UPF0304 family
JHT10_12885	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHT10_12895	COG1882	Formate acetyltransferase
JHT10_12935	COG0708	Exodeoxyribonuclease III
JHT10_12945	COG3923	Primosomal replication protein n
JHT10_12950	COG0730	response to heat
JHT10_12955	COG1199	ATP-dependent helicase activity
JHT10_12965	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JHT10_12970	COG1187	pseudouridine synthase activity
JHT10_12980	COG1278	Cold shock
JHT10_12985	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JHT10_12990	COG0542	response to heat
JHT10_13000	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JHT10_13005	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JHT10_13010	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JHT10_13020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JHT10_13030	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHT10_13035	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JHT10_13040	COG0297	glycogen (starch) synthase activity
JHT10_13060	COG3070	regulator of competence-specific genes
JHT10_13065	COG1609	Transcriptional regulator
JHT10_13070	COG3381	protein complex oligomerization
JHT10_13075	COG0745	RESPONSE REGULATOR receiver
JHT10_13080	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JHT10_13085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JHT10_13090	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
JHT10_13095	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
JHT10_13100	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JHT10_13120	COG0189	ligase activity
JHT10_13120	COG4067	protein conserved in archaea
JHT10_13125	COG0500	methyltransferase
JHT10_13130	COG4106	trans-aconitate 2-methyltransferase activity
JHT10_13135	COG1801	Protein of unknown function DUF72
JHT10_13140	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JHT10_13145	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JHT10_13150	COG0840	transmembrane signaling receptor activity
JHT10_13155	COG0632	four-way junction helicase activity
JHT10_13160	COG2255	four-way junction helicase activity
JHT10_13165	COG1271	oxidase subunit
JHT10_13170	COG1294	oxidase, subunit
JHT10_13175	COG4890	Cyd operon protein YbgT
JHT10_13185	COG0824	Thioesterase
JHT10_13190	COG0811	peptide transport
JHT10_13205	COG0823	Involved in the tonB-independent uptake of proteins
JHT10_13210	COG2885	chlorophyll binding
JHT10_13215	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JHT10_13220	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JHT10_13230	COG3766	membrane
JHT10_13240	COG0754	glutathionylspermidine amidase activity
JHT10_13250	COG0784	Response regulator, receiver
JHT10_13250	COG5002	protein histidine kinase activity
JHT10_13265	COG0840	transmembrane signaling receptor activity
JHT10_13270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_13275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_13300	COG3568	Endonuclease Exonuclease Phosphatase
JHT10_13315	COG0583	DNA-binding transcription factor activity
JHT10_13325	COG0686	Belongs to the AlaDH PNT family
JHT10_13335	COG1674	ftsk spoiiie
JHT10_13340	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JHT10_13345	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JHT10_13350	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JHT10_13360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JHT10_13365	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JHT10_13370	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JHT10_13375	COG0156	8-amino-7-oxononanoate synthase activity
JHT10_13385	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JHT10_13395	COG0501	Belongs to the peptidase M48B family
JHT10_13405	COG0300	oxidoreductase activity
JHT10_13420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JHT10_13440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JHT10_13445	COG2915	High frequency lysogenization protein hflD homolog
JHT10_13450	COG0482	sulfurtransferase activity
JHT10_13460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHT10_13470	COG1757	Na H antiporter
JHT10_13485	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JHT10_13490	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JHT10_13495	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JHT10_13500	COG0131	Imidazoleglycerol-phosphate dehydratase
JHT10_13500	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JHT10_13505	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JHT10_13510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JHT10_13515	COG0107	imidazoleglycerol-phosphate synthase activity
JHT10_13520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JHT10_13520	COG0140	phosphoribosyl-ATP diphosphatase activity
JHT10_13525	COG3012	SEC-C Motif Domain Protein
JHT10_13530	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JHT10_13535	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHT10_13540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JHT10_13545	COG0215	cysteine-tRNA ligase activity
JHT10_13550	COG1435	thymidine kinase activity
JHT10_13555	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JHT10_13580	COG2116	formate transmembrane transporter activity
JHT10_13590	COG0390	transport system, permease component
JHT10_13595	COG4459	periplasmic nitrate reductase
JHT10_13600	COG3005	denitrification pathway
JHT10_13605	COG0243	molybdopterin cofactor binding
JHT10_13620	COG1227	inorganic diphosphatase activity
JHT10_13630	COG4172	Belongs to the ABC transporter superfamily
JHT10_13640	COG4171	peptide transport system, permease
JHT10_13655	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JHT10_13660	COG1842	Phage shock protein A
JHT10_13675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_13690	COG2818	Glycosylase
JHT10_13695	COG5380	lipid catabolic process
JHT10_13700	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JHT10_13705	COG0626	cystathionine gamma-synthase activity
JHT10_13715	COG0733	neurotransmitter:sodium symporter activity
JHT10_13725	COG0564	pseudouridine synthase activity
JHT10_13735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JHT10_13740	COG1151	hydroxylamine reductase activity
JHT10_13745	COG3604	Transcriptional regulator
JHT10_13755	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JHT10_13760	COG4136	ATPase activity
JHT10_13765	COG4135	transport system, permease component
JHT10_13770	COG4134	Bacterial extracellular solute-binding protein
JHT10_13775	COG0398	Pfam SNARE associated Golgi protein
JHT10_13785	COG0493	'glutamate synthase
JHT10_13810	COG3313	Fe-S protein
JHT10_13835	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JHT10_13855	COG1061	Type III restriction enzyme res subunit
JHT10_13860	COG1187	pseudouridine synthase activity
JHT10_13865	COG2814	Major facilitator Superfamily
JHT10_13895	COG3005	denitrification pathway
JHT10_13900	COG0702	epimerase
JHT10_13905	COG0534	Mate efflux family protein
JHT10_13910	COG4181	ATPase activity
JHT10_13925	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JHT10_13940	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JHT10_13945	COG2985	domain, Protein
JHT10_13945	COG3273	potassium ion transport
JHT10_13950	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JHT10_13960	COG1737	Transcriptional regulator
JHT10_13965	COG0076	glutamate decarboxylase activity
JHT10_13975	COG2431	L-lysine efflux transmembrane transporter activity
JHT10_13985	COG3070	regulator of competence-specific genes
JHT10_14000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_14000	COG4191	Histidine kinase
JHT10_14010	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JHT10_14015	COG3048	D-serine ammonia-lyase activity
JHT10_14020	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JHT10_14025	COG4988	ABC transporter
JHT10_14030	COG0492	ferredoxin-NADP+ reductase activity
JHT10_14055	COG0471	metal ion transport
JHT10_14060	COG2949	membrane
JHT10_14065	COG0281	malic enzyme
JHT10_14070	COG1643	Atp-dependent helicase
JHT10_14075	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
JHT10_14090	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JHT10_14125	COG0277	FAD linked oxidase domain protein
JHT10_14125	COG0247	lactate metabolic process
JHT10_14140	COG2986	histidine ammonia-lyase
JHT10_14145	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JHT10_14150	COG0010	Belongs to the arginase family
JHT10_14155	COG1228	amidohydrolase
JHT10_14160	COG2188	Transcriptional regulator
JHT10_14175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JHT10_14185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JHT10_14195	COG0393	Putative heavy-metal-binding
JHT10_14225	COG3706	GGDEF domain
JHT10_14230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JHT10_14235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHT10_14235	COG0072	phenylalanine-tRNA ligase activity
JHT10_14245	COG0776	regulation of translation
JHT10_14255	COG0500	methyltransferase
JHT10_14260	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JHT10_14265	COG0295	cytidine deaminase activity
JHT10_14270	COG1346	cytolysis
JHT10_14275	COG1380	Effector of murein hydrolase LrgA
JHT10_14280	COG2925	Exonuclease
JHT10_14285	COG1823	symporter activity
JHT10_14290	COG0702	epimerase
JHT10_14295	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JHT10_14300	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JHT10_14310	COG2062	phosphohistidine phosphatase, SixA
JHT10_14320	COG2988	succinylglutamate desuccinylase activity
JHT10_14325	COG4139	cobalamin transport
JHT10_14330	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
JHT10_14350	COG0583	DNA-binding transcription factor activity
JHT10_14370	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JHT10_14375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JHT10_14380	COG3475	LICD family
JHT10_14385	COG1451	nucleotide metabolic process
JHT10_14390	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
JHT10_14420	COG3938	Belongs to the proline racemase family
JHT10_14435	COG2423	ornithine cyclodeaminase activity
JHT10_14440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JHT10_14445	COG3842	ATPase activity
JHT10_14450	COG1176	ABC-type spermidine putrescine transport system, permease component I
JHT10_14455	COG1177	transmembrane transport
JHT10_14465	COG3291	Pkd domain containing protein
JHT10_14485	COG0444	Belongs to the ABC transporter superfamily
JHT10_14490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHT10_14495	COG0601	transmembrane transport
JHT10_14505	COG2195	Cleaves the N-terminal amino acid of tripeptides
JHT10_14515	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JHT10_14525	COG0625	glutathione transferase activity
JHT10_14590	COG0583	DNA-binding transcription factor activity
JHT10_14625	COG0471	metal ion transport
JHT10_14630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_14630	COG4191	Histidine kinase
JHT10_14640	COG3300	MHYT domain
JHT10_14640	COG5001	Diguanylate cyclase
JHT10_14650	COG1280	lysine exporter protein (LysE YggA)
JHT10_14655	COG1328	CTP reductase activity
JHT10_14660	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHT10_14670	COG0861	Integral membrane protein TerC family
JHT10_14675	COG0739	heme binding
JHT10_14715	COG3501	Rhs element vgr protein
JHT10_14740	COG0515	serine threonine protein kinase
JHT10_14775	COG1522	sequence-specific DNA binding
JHT10_14865	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JHT10_14875	COG0814	amino acid
JHT10_14895	COG1132	(ABC) transporter
JHT10_14900	COG1132	(ABC) transporter
JHT10_14925	COG0443	Heat shock 70 kDa protein
JHT10_14930	COG0443	Heat shock 70 kDa protein
JHT10_14940	COG3706	GGDEF domain
JHT10_14970	COG0243	molybdopterin cofactor binding
JHT10_14975	COG0437	4 iron, 4 sulfur cluster binding
JHT10_14980	COG3302	dmso reductase anchor subunit
JHT10_14995	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JHT10_15000	COG1643	Atp-dependent helicase
JHT10_15015	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHT10_15025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JHT10_15030	COG1215	transferase activity, transferring glycosyl groups
JHT10_15035	COG0438	transferase activity, transferring glycosyl groups
JHT10_15065	COG0438	transferase activity, transferring glycosyl groups
JHT10_15075	COG2204	response regulator
JHT10_15105	COG1793	dna ligase
JHT10_15115	COG0534	Mate efflux family protein
JHT10_15120	COG0307	riboflavin synthase, alpha
JHT10_15130	COG3001	Fructosamine kinase
JHT10_15135	COG2201	protein-glutamate methylesterase activity
JHT10_15140	COG3706	GGDEF domain
JHT10_15150	COG0791	NLP P60 protein
JHT10_15155	COG0840	transmembrane signaling receptor activity
JHT10_15155	COG3290	protein histidine kinase activity
JHT10_15190	COG3148	PFAM DTW domain containing protein
JHT10_15195	COG1940	carbohydrate kinase activity
JHT10_15205	COG0303	'Molybdopterin
JHT10_15210	COG0746	molybdenum cofactor guanylyltransferase activity
JHT10_15215	COG3842	ATPase activity
JHT10_15230	COG2204	response regulator
JHT10_15235	COG4191	Histidine kinase
JHT10_15240	COG0488	(ABC) transporter
JHT10_15245	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JHT10_15265	COG3381	protein complex oligomerization
JHT10_15275	COG3383	formate dehydrogenase (NAD+) activity
JHT10_15275	COG0243	molybdopterin cofactor binding
JHT10_15280	COG0437	4 iron, 4 sulfur cluster binding
JHT10_15305	COG0004	ammonium transporteR
JHT10_15315	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JHT10_15320	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JHT10_15330	COG1177	transmembrane transport
JHT10_15340	COG3842	ATPase activity
JHT10_15360	COG0037	tRNA processing
JHT10_15365	COG0589	response to stress
JHT10_15370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHT10_15385	COG2217	Heavy metal translocating P-type atpase
JHT10_15395	COG2010	Cytochrome c
JHT10_15410	COG3278	Belongs to the heme-copper respiratory oxidase family
JHT10_15425	COG0784	Response regulator, receiver
JHT10_15425	COG2205	protein histidine kinase activity
JHT10_15460	COG3120	sequence-specific DNA binding
JHT10_15465	COG1067	ATP-dependent peptidase activity
JHT10_15470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JHT10_15485	COG0488	(ABC) transporter
JHT10_15495	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JHT10_15495	COG0116	Belongs to the methyltransferase superfamily
JHT10_15505	COG0167	dihydroorotate dehydrogenase activity
JHT10_15510	COG2902	Dehydrogenase
JHT10_15520	COG0308	aminopeptidase N
JHT10_15535	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JHT10_15540	COG1956	GAF domain-containing protein
JHT10_15545	COG1132	(ABC) transporter
JHT10_15550	COG2995	paraquat-inducible protein a
JHT10_15555	COG3008	intermembrane lipid transfer
JHT10_15560	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JHT10_15560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JHT10_15580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JHT10_15585	COG1666	GTP binding
JHT10_15595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_15600	COG4597	amino acid ABC transporter
JHT10_15605	COG0765	amino acid transport
JHT10_15610	COG1126	abc transporter atp-binding protein
JHT10_15615	COG0670	Belongs to the BI1 family
JHT10_15625	COG2920	part of a sulfur-relay system
JHT10_15630	COG1254	Belongs to the acylphosphatase family
JHT10_15635	COG0840	transmembrane signaling receptor activity
JHT10_15640	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JHT10_15680	COG3706	GGDEF domain
JHT10_15685	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JHT10_15690	COG0602	queuosine metabolic process
JHT10_15695	COG0561	phosphatase activity
JHT10_15720	COG2828	Protein conserved in bacteria
JHT10_15730	COG0372	Belongs to the citrate synthase family
JHT10_15735	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JHT10_15765	COG0730	response to heat
JHT10_15785	COG0457	Tetratricopeptide repeat
JHT10_15855	COG4790	Type iii secretion
JHT10_15860	COG4794	Type iii secretion
JHT10_15865	COG4791	protein targeting
JHT10_15870	COG4792	protein secretion
JHT10_15880	COG1073	alpha beta
JHT10_15885	COG1073	alpha beta
JHT10_15895	COG0583	DNA-binding transcription factor activity
JHT10_15930	COG3177	Filamentation induced by cAMP protein fic
JHT10_15950	COG4669	(LipO)protein
JHT10_16020	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_16025	COG3284	Transcriptional regulator
JHT10_16040	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JHT10_16045	COG0363	glucosamine-6-phosphate deaminase activity
JHT10_16050	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JHT10_16055	COG4565	transcriptional regulatory protein
JHT10_16060	COG3290	protein histidine kinase activity
JHT10_16075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_16090	COG1858	cytochrome C peroxidase
JHT10_16095	COG0527	aspartate kinase activity
JHT10_16100	COG0662	Cupin 2, conserved barrel domain protein
JHT10_16105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHT10_16110	COG0456	acetyltransferase
JHT10_16115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHT10_16135	COG4176	ABC-type proline glycine betaine transport system permease component
JHT10_16140	COG2113	Glycine betaine
JHT10_16160	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_16170	COG0745	RESPONSE REGULATOR receiver
JHT10_16175	COG0642	Histidine kinase
JHT10_16180	COG1368	sulfuric ester hydrolase activity
JHT10_16205	COG1115	amino acid carrier protein
JHT10_16215	COG1280	lysine exporter protein (LysE YggA)
JHT10_16220	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JHT10_16225	COG1560	Kdo2-lipid A biosynthetic process
JHT10_16230	COG0531	amino acid
JHT10_16240	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JHT10_16245	COG3063	Type IV pilus biogenesis stability protein PilW
JHT10_16275	COG0110	maltose O-acetyltransferase activity
JHT10_16295	COG2315	Protein conserved in bacteria
JHT10_16300	COG1846	Transcriptional regulator
JHT10_16315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JHT10_16325	COG2771	luxR family
JHT10_16325	COG2200	EAL domain
JHT10_16330	COG1227	inorganic diphosphatase activity
JHT10_16335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHT10_16340	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_16345	COG2957	Belongs to the agmatine deiminase family
JHT10_16355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JHT10_16360	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_16365	COG1396	sequence-specific DNA binding
JHT10_16365	COG1917	Cupin 2, conserved barrel domain protein
JHT10_16370	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JHT10_16375	COG0174	glutamine synthetase
JHT10_16380	COG1757	Na H antiporter
JHT10_16440	COG2026	Addiction module toxin, RelE StbE family
JHT10_16455	COG0653	protein targeting
JHT10_16485	COG0456	acetyltransferase
JHT10_16485	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JHT10_16545	COG0251	oxidation-reduction process
JHT10_16630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JHT10_16635	COG2194	sulfuric ester hydrolase activity
JHT10_16650	COG3422	double-strand break repair
JHT10_16680	COG0582	viral genome integration into host DNA
JHT10_16690	COG1280	lysine exporter protein (LysE YggA)
JHT10_16760	COG0456	acetyltransferase
JHT10_16840	COG1280	lysine exporter protein (LysE YggA)
JHT10_16850	COG1280	lysine exporter protein (LysE YggA)
JHT10_17040	COG0454	-acetyltransferase
JHT10_17050	COG0456	acetyltransferase
JHT10_17080	COG0346	lactoylglutathione lyase activity
JHT10_17090	COG0251	oxidation-reduction process
JHT10_17310	COG0346	lactoylglutathione lyase activity
JHT10_17470	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHT10_17480	COG3768	UPF0283 membrane protein
JHT10_17485	COG3106	COG3106 Predicted ATPase
JHT10_17500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JHT10_17505	COG0784	Response regulator, receiver
JHT10_17505	COG2205	protein histidine kinase activity
JHT10_17515	COG0494	nUDIX hydrolase
JHT10_17520	COG0814	amino acid
JHT10_17525	COG1760	l-serine dehydratase
JHT10_17530	COG2200	EAL domain
JHT10_17540	COG0720	synthase
JHT10_17550	COG0017	Asparaginyl-tRNA synthetase
JHT10_17560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHT10_17575	COG1448	Aminotransferase
JHT10_17595	COG0840	transmembrane signaling receptor activity
JHT10_17600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHT10_17605	COG1846	Transcriptional regulator
JHT10_17630	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JHT10_17645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JHT10_17650	COG3108	Peptidase M15
JHT10_17655	COG2989	Protein conserved in bacteria
JHT10_17680	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JHT10_17690	COG3088	subunit of a heme lyase
JHT10_17690	COG4235	cytochrome complex assembly
JHT10_17700	COG1138	Cytochrome C-type biogenesis protein
JHT10_17705	COG3301	Polysulphide reductase, NrfD
JHT10_17710	COG0437	4 iron, 4 sulfur cluster binding
JHT10_17720	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JHT10_17740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JHT10_17745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHT10_17750	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHT10_17775	COG0019	diaminopimelate decarboxylase activity
JHT10_17815	COG0322	excinuclease ABC activity
JHT10_17820	COG2197	response regulator
JHT10_17825	COG0417	DNA replication proofreading
JHT10_17835	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JHT10_17840	COG3099	Belongs to the UPF0263 family
JHT10_17845	COG1187	pseudouridine synthase activity
JHT10_17855	COG0009	L-threonylcarbamoyladenylate synthase
JHT10_17860	COG0613	PHP domain protein
JHT10_17870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JHT10_17875	COG0512	Glutamine amidotransferase of anthranilate synthase
JHT10_17880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JHT10_17885	COG0134	indole-3-glycerol-phosphate synthase activity
JHT10_17885	COG0135	phosphoribosylanthranilate isomerase activity
JHT10_17890	COG0133	tryptophan synthase activity
JHT10_17895	COG0159	tryptophan synthase activity
JHT10_17900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHT10_17905	COG0318	PFAM AMP-dependent synthetase and ligase
JHT10_17910	COG1301	dicarboxylic acid transport
JHT10_17930	COG2917	probably involved in intracellular septation
JHT10_17940	COG2350	Protein conserved in bacteria
JHT10_17950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JHT10_17955	COG0583	DNA-binding transcription factor activity
JHT10_17970	COG5001	Diguanylate cyclase
JHT10_17970	COG2203	Gaf domain
JHT10_17970	COG3706	GGDEF domain
JHT10_17970	COG4251	negative regulation of phosphorylation
JHT10_17975	COG1032	radical SAM domain protein
JHT10_17980	COG0840	transmembrane signaling receptor activity
JHT10_17985	COG0745	RESPONSE REGULATOR receiver
JHT10_17990	COG3850	Histidine kinase
JHT10_17990	COG5002	protein histidine kinase activity
JHT10_18040	COG1335	isochorismatase
JHT10_18045	COG0577	efflux transmembrane transporter activity
JHT10_18045	COG1136	(ABC) transporter
JHT10_18050	COG0577	efflux transmembrane transporter activity
JHT10_18050	COG1136	(ABC) transporter
JHT10_18055	COG1136	(ABC) transporter
JHT10_18055	COG0577	efflux transmembrane transporter activity
JHT10_18065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHT10_18095	COG3118	belongs to the thioredoxin family
JHT10_18100	COG4232	protein-disulfide reductase activity
JHT10_18140	COG2863	cytochrome
JHT10_18145	COG3258	Cytochrome c
JHT10_18150	COG2995	paraquat-inducible protein a
JHT10_18155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JHT10_18155	COG3008	intermembrane lipid transfer
JHT10_18165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JHT10_18190	COG4166	transmembrane transport
JHT10_18195	COG0284	orotidine-5'-phosphate decarboxylase activity
JHT10_18200	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JHT10_18205	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
JHT10_18215	COG0539	negative regulation of cytoplasmic translation
JHT10_18220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JHT10_18225	COG0616	signal peptide processing
JHT10_18230	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_18245	COG0587	DNA-directed DNA polymerase activity
JHT10_18250	COG0784	Response regulator, receiver
JHT10_18250	COG0835	chemotaxis
JHT10_18255	COG1940	carbohydrate kinase activity
JHT10_18260	COG0469	pyruvate kinase activity
JHT10_18265	COG4667	esterase of the alpha-beta hydrolase superfamily
JHT10_18280	COG0733	neurotransmitter:sodium symporter activity
JHT10_18295	COG1263	PTS System
JHT10_18295	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHT10_18300	COG0084	hydrolase, TatD family'
JHT10_18310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JHT10_18315	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JHT10_18345	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JHT10_18350	COG0416	fatty acid biosynthetic process
JHT10_18360	COG1399	metal-binding, possibly nucleic acid-binding protein
JHT10_18365	COG0424	maF-like protein
JHT10_18370	COG0564	pseudouridine synthase activity
JHT10_18375	COG1530	ribonuclease E activity
JHT10_18380	COG0659	secondary active sulfate transmembrane transporter activity
JHT10_18385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JHT10_18390	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JHT10_18400	COG0572	uridine kinase
JHT10_18405	COG0489	protein tyrosine kinase activity
JHT10_18410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHT10_18410	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHT10_18420	COG2186	Transcriptional regulator
JHT10_18425	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JHT10_18430	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JHT10_18435	COG0653	protein targeting
JHT10_18440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHT10_18450	COG0366	Alpha amylase catalytic
JHT10_18455	COG1122	ATPase activity
JHT10_18460	COG4120	Belongs to the binding-protein-dependent transport system permease family
JHT10_18470	COG3092	negative regulation of chromosome organization
JHT10_18475	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHT10_18480	COG0280	phosphate acetyltransferase
JHT10_18480	COG0857	belongs to the CobB CobQ family
JHT10_18485	COG3174	membrane
JHT10_18495	COG0435	Glutathione S-transferase
JHT10_18505	COG0444	Belongs to the ABC transporter superfamily
JHT10_18510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHT10_18515	COG0601	transmembrane transport
JHT10_18525	COG0314	molybdopterin synthase activity
JHT10_18530	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JHT10_18535	COG0315	cyclic pyranopterin monophosphate synthase activity
JHT10_18540	COG0521	Mo-molybdopterin cofactor biosynthetic process
JHT10_18545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JHT10_18550	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JHT10_18555	COG2198	Histidine kinase
JHT10_18560	COG2204	response regulator
JHT10_18565	COG0556	nucleotide-excision repair
JHT10_18575	COG4657	Part of a membrane complex involved in electron transport
JHT10_18580	COG2878	Part of a membrane complex involved in electron transport
JHT10_18585	COG4656	Part of a membrane complex involved in electron transport
JHT10_18590	COG4658	electron transport chain
JHT10_18595	COG4659	FMN binding
JHT10_18600	COG4660	Part of a membrane complex involved in electron transport
JHT10_18605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JHT10_18610	COG0346	lactoylglutathione lyase activity
JHT10_18620	COG2885	chlorophyll binding
JHT10_18625	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JHT10_18630	COG2056	Na+-H+ antiporter family
JHT10_18640	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JHT10_18660	COG1454	alcohol dehydrogenase
JHT10_18660	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_18665	COG2095	MarC family integral membrane protein
JHT10_18670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHT10_18675	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JHT10_18680	COG1757	Na H antiporter
JHT10_18695	COG3081	Nucleoid-associated protein
JHT10_18700	COG3082	Protein of unknown function (DUF1414)
JHT10_18705	COG3083	sulfuric ester hydrolase activity
JHT10_18715	COG0123	including yeast histone deacetylase and acetoin utilization protein
JHT10_18730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHT10_18735	COG0778	Nitroreductase
JHT10_18740	COG1902	pentaerythritol trinitrate reductase activity
JHT10_18740	COG0446	pyridine nucleotide-disulphide oxidoreductase
JHT10_18745	COG0616	signal peptide processing
JHT10_18750	COG0252	asparaginase activity
JHT10_18755	COG3139	Protein of unknown function (DUF1315)
JHT10_18765	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHT10_18770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JHT10_18785	COG2226	methyltransferase
JHT10_18800	COG1785	Belongs to the alkaline phosphatase family
JHT10_18810	COG0346	lactoylglutathione lyase activity
JHT10_18815	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JHT10_18820	COG0668	transmembrane transport
JHT10_18825	COG2983	Belongs to the UPF0260 family
JHT10_18830	COG2261	transglycosylase associated protein
JHT10_18845	COG3681	Belongs to the UPF0597 family
JHT10_18850	COG0251	oxidation-reduction process
JHT10_18855	COG0814	amino acid
JHT10_18860	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JHT10_18865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JHT10_18870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JHT10_18880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JHT10_18885	COG2832	Protein of unknown function (DUF454)
JHT10_18890	COG0745	RESPONSE REGULATOR receiver
JHT10_18895	COG0583	DNA-binding transcription factor activity
JHT10_18905	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JHT10_18910	COG1286	toxin biosynthetic process
JHT10_18915	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
JHT10_18920	COG0285	dihydrofolate synthase activity
JHT10_18925	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JHT10_18930	COG0101	tRNA pseudouridine synthase activity
JHT10_18940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JHT10_18945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JHT10_18950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JHT10_18955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JHT10_18955	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JHT10_18960	COG0431	NADPH-dependent FMN reductase
JHT10_18970	COG3101	peptidyl-lysine hydroxylation
JHT10_18975	COG2860	membrane
JHT10_18980	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JHT10_18985	COG2890	protein-(glutamine-N5) methyltransferase activity
JHT10_18990	COG2840	Smr protein MutS2
JHT10_18995	COG2062	phosphohistidine phosphatase, SixA
JHT10_19010	COG1250	3-hydroxyacyl-CoA dehydrogenase
JHT10_19010	COG1024	Enoyl-CoA hydratase
JHT10_19015	COG0183	Belongs to the thiolase family
JHT10_19030	COG2067	long-chain fatty acid transport protein
JHT10_19040	COG2853	Lipoprotein
JHT10_19055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JHT10_19060	COG1138	Cytochrome C-type biogenesis protein
JHT10_19065	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JHT10_19070	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JHT10_19075	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JHT10_19080	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JHT10_19085	COG4133	protoheme IX ABC transporter activity
JHT10_19095	COG0835	chemotaxis
JHT10_19105	COG1192	Involved in chromosome partitioning
JHT10_19110	COG2201	protein-glutamate methylesterase activity
JHT10_19115	COG0643	Histidine kinase
JHT10_19115	COG0784	Response regulator, receiver
JHT10_19115	COG2198	Histidine kinase
JHT10_19120	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JHT10_19160	COG1987	bacterial-type flagellum assembly
JHT10_19210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JHT10_19220	COG1677	Flagellar hook-basal body complex protein FliE
JHT10_19240	COG1516	flagellar protein fliS
JHT10_19250	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JHT10_19255	COG1334	flagellar protein FlaG
JHT10_19260	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_19265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_19270	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHT10_19275	COG2837	iron assimilation
JHT10_19300	COG1393	Belongs to the ArsC family
JHT10_19305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JHT10_19320	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JHT10_19325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JHT10_19330	COG2716	regulation of RNA biosynthetic process
JHT10_19335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JHT10_19350	COG4783	chaperone-mediated protein folding
JHT10_19355	COG1393	Belongs to the ArsC family
JHT10_19375	COG2233	PERMEase
JHT10_19380	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JHT10_19385	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JHT10_19390	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JHT10_19395	COG0121	glutamine amidotransferase
JHT10_19400	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JHT10_19405	COG1960	acyl-CoA dehydrogenase activity
JHT10_19420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JHT10_19425	COG0328	RNA-DNA hybrid ribonuclease activity
JHT10_19430	COG2226	methyltransferase
JHT10_19435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JHT10_19440	COG0741	lytic transglycosylase activity
JHT10_19440	COG1388	LysM domain
JHT10_19450	COG3021	interspecies interaction between organisms
JHT10_19455	COG0347	Belongs to the P(II) protein family
JHT10_19465	COG0037	tRNA processing
JHT10_19470	COG0825	malonyl-CoA metabolic process
JHT10_19475	COG0587	DNA-directed DNA polymerase activity
JHT10_19480	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JHT10_19485	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHT10_19490	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHT10_19495	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JHT10_19500	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHT10_19505	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
JHT10_19515	COG0750	zinc metalloprotease
JHT10_19520	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JHT10_19525	COG0575	Belongs to the CDS family
JHT10_19530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JHT10_19535	COG0233	cytoplasmic translational termination
JHT10_19540	COG0528	UMP kinase activity
JHT10_19545	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JHT10_19550	COG0052	Belongs to the universal ribosomal protein uS2 family
JHT10_19555	COG0024	Methionine aminopeptidase
JHT10_19560	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JHT10_19570	COG0564	pseudouridine synthase activity
JHT10_19575	COG3098	single-species biofilm formation
JHT10_19600	COG1671	Belongs to the UPF0178 family
JHT10_19605	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JHT10_19615	COG0254	rRNA binding
JHT10_19620	COG1720	tRNA m6t6A37 methyltransferase activity
JHT10_19625	COG0442	prolyl-tRNA aminoacylation
JHT10_19645	COG0733	neurotransmitter:sodium symporter activity
JHT10_19660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHT10_19665	COG0514	ATP-dependent DNA helicase (RecQ)
JHT10_19670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JHT10_19685	COG1477	protein flavinylation
JHT10_19690	COG2871	sodium ion transport
JHT10_19695	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHT10_19700	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHT10_19705	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHT10_19710	COG1805	sodium ion transport
JHT10_19715	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHT10_19720	COG0271	Belongs to the BolA IbaG family
JHT10_19725	COG2813	Specifically methylates the guanine in position
JHT10_19730	COG3056	Lipoprotein
JHT10_19750	COG1595	DNA-templated transcription, initiation
JHT10_19770	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JHT10_19775	COG0693	protein deglycase activity
JHT10_19780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JHT10_19785	COG3706	GGDEF domain
JHT10_19790	COG2166	iron-sulfur cluster assembly
JHT10_19795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JHT10_19800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JHT10_19810	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JHT10_19810	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JHT10_19820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JHT10_19825	COG1074	ATP-dependent DNA helicase activity
JHT10_19830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JHT10_19850	COG3141	response to X-ray
JHT10_19855	COG2171	N-acyltransferase activity
JHT10_19860	COG0584	glycerophosphoryl diester phosphodiesterase
JHT10_19865	COG2271	Major facilitator Superfamily
JHT10_19870	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JHT10_19875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JHT10_19885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JHT10_19890	COG0598	Magnesium transport protein CorA
JHT10_19905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHT10_19910	COG1609	Transcriptional regulator
JHT10_19915	COG2176	DNA-directed DNA polymerase activity
JHT10_19930	COG2017	converts alpha-aldose to the beta-anomer
JHT10_19935	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JHT10_19940	COG1085	galactose-1-phosphate uridylyltransferase
JHT10_19945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JHT10_19950	COG1609	Transcriptional regulator
JHT10_19955	COG3250	beta-galactosidase activity
JHT10_19960	COG2731	YhcH YjgK YiaL family protein
JHT10_19965	COG0531	amino acid
JHT10_19970	COG0583	DNA-binding transcription factor activity
JHT10_20030	COG4964	Belongs to the GSP D family
JHT10_20055	COG2169	Transcriptional regulator
JHT10_20060	COG1022	Amp-dependent synthetase and ligase
JHT10_20070	COG0583	DNA-binding transcription factor activity
JHT10_20075	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JHT10_20080	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JHT10_20090	COG0560	Phosphoserine phosphatase
JHT10_20100	COG0813	purine-nucleoside phosphorylase activity
JHT10_20105	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JHT10_20110	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JHT10_20115	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JHT10_20120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHT10_20125	COG0084	hydrolase, TatD family'
JHT10_20135	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JHT10_20155	COG3153	acetyltransferase
JHT10_20160	COG3154	lipid carrier protein
JHT10_20170	COG0826	peptidase U32
JHT10_20175	COG0826	peptidase U32
JHT10_20180	COG0534	Mate efflux family protein
JHT10_20195	COG1185	polyribonucleotide nucleotidyltransferase activity
JHT10_20200	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JHT10_20205	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JHT10_20210	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JHT10_20215	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JHT10_20220	COG0195	Participates in both transcription termination and antitermination
JHT10_20225	COG0779	Required for maturation of 30S ribosomal subunits
JHT10_20240	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JHT10_20245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHT10_20250	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JHT10_20255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JHT10_20260	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JHT10_20265	COG1534	Rna-binding protein
JHT10_20270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHT10_20275	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JHT10_20280	COG2027	D-alanyl-D-alanine carboxypeptidase
JHT10_20290	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JHT10_20295	COG0739	heme binding
JHT10_20300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHT10_20310	COG0316	Belongs to the HesB IscA family
JHT10_20315	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JHT10_20320	COG0628	permease
JHT10_20325	COG2813	Specifically methylates the guanine in position
JHT10_20330	COG2198	Histidine kinase
JHT10_20330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_20330	COG2205	protein histidine kinase activity
JHT10_20330	COG0784	Response regulator, receiver
JHT10_20335	COG0747	negative chemotaxis
JHT10_20345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHT10_20350	COG0444	Belongs to the ABC transporter superfamily
JHT10_20355	COG4608	Belongs to the ABC transporter superfamily
JHT10_20365	COG2971	BadF BadG BcrA BcrD
JHT10_20380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHT10_20385	COG3842	ATPase activity
JHT10_20395	COG1840	ABC-type Fe3 transport system, periplasmic component
JHT10_20400	COG0004	ammonium transporteR
JHT10_20410	COG3112	Uncharacterised protein family (UPF0231)
JHT10_20415	COG1049	propionate catabolic process, 2-methylcitrate cycle
JHT10_20420	COG1752	Esterase of the alpha-beta hydrolase superfamily
JHT10_20425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JHT10_20430	COG1643	Atp-dependent helicase
JHT10_20435	COG1489	DNA binding
JHT10_20445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHT10_20455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JHT10_20460	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JHT10_20465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JHT10_20470	COG1560	Kdo2-lipid A biosynthetic process
JHT10_20475	COG0842	Transport permease protein
JHT10_20480	COG1131	(ABC) transporter
JHT10_20485	COG0659	secondary active sulfate transmembrane transporter activity
JHT10_20490	COG0288	reversible hydration of carbon dioxide
JHT10_20505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JHT10_20510	COG0508	dehydrogenase complex catalyzes the overall conversion of
JHT10_20515	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JHT10_20520	COG2186	Transcriptional regulator
JHT10_20530	COG0157	Belongs to the NadC ModD family
JHT10_20535	COG4969	Belongs to the N-Me-Phe pilin family
JHT10_20540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHT10_20545	COG1459	type II secretion system
JHT10_20555	COG0237	dephospho-CoA kinase activity
JHT10_20560	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
JHT10_20565	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JHT10_20570	COG0335	large ribosomal subunit rRNA binding
JHT10_20575	COG0336	Belongs to the RNA methyltransferase TrmD family
JHT10_20580	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JHT10_20585	COG0228	four-way junction DNA binding
JHT10_20590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JHT10_20595	COG4137	Cytochrome C assembly protein
JHT10_20600	COG4536	flavin adenine dinucleotide binding
JHT10_20605	COG1854	S-ribosylhomocysteine lyase activity
JHT10_20615	COG2918	glutathione biosynthetic process
JHT10_20620	COG0612	Peptidase, M16
JHT10_20625	COG1238	metal cluster binding
JHT10_20635	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JHT10_20640	COG0511	ligase activity, forming carbon-carbon bonds
JHT10_20640	COG5016	pyruvate
JHT10_20645	COG3630	sodium ion export across plasma membrane
JHT10_20695	COG0527	aspartate kinase activity
JHT10_20700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JHT10_20705	COG2137	regulation of response to DNA damage stimulus
JHT10_20710	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JHT10_20715	COG1546	Belongs to the CinA family
JHT10_20720	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JHT10_20725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JHT10_20735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JHT10_20740	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JHT10_20745	COG0585	pseudouridine synthase activity
JHT10_20750	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JHT10_20755	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JHT10_20760	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JHT10_20765	COG0148	phosphopyruvate hydratase activity
JHT10_20770	COG0504	CTP synthase activity
JHT10_20775	COG3956	TIGRFAM MazG family protein
JHT10_20780	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JHT10_20785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JHT10_20795	COG0736	holo-[acyl-carrier-protein] synthase activity
JHT10_20800	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JHT10_20805	COG1381	Involved in DNA repair and RecF pathway recombination
JHT10_20810	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JHT10_20815	COG0571	ribonuclease III activity
JHT10_20825	COG0481	GTPase activity
JHT10_20830	COG3086	response to oxidative stress
JHT10_20840	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
JHT10_20845	COG1595	DNA-templated transcription, initiation
JHT10_20850	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JHT10_20855	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JHT10_20860	COG0354	folic acid binding
JHT10_20875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JHT10_20880	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JHT10_20885	COG3079	Belongs to the UPF0149 family
JHT10_20890	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JHT10_20900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JHT10_20905	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JHT10_20910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JHT10_20920	COG0583	DNA-binding transcription factor activity
JHT10_20930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JHT10_20935	COG0668	transmembrane transport
JHT10_20940	COG0191	fructose-bisphosphate aldolase activity
JHT10_20945	COG0126	phosphoglycerate kinase activity
JHT10_20950	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JHT10_20955	COG4771	TonB-dependent receptor
JHT10_20960	COG0583	DNA-binding transcription factor activity
JHT10_20965	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JHT10_20970	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JHT10_20980	COG3091	SprT-like family
JHT10_20985	COG2356	endonuclease I
JHT10_20990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JHT10_20995	COG0189	ligase activity
JHT10_21000	COG1678	Uncharacterized ACR, COG1678
JHT10_21005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JHT10_21020	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JHT10_21025	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JHT10_21030	COG0762	integral membrane protein
JHT10_21035	COG1872	DUF167
JHT10_21045	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JHT10_21050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JHT10_21055	COG2066	Belongs to the glutaminase family
JHT10_21065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JHT10_21075	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JHT10_21080	COG0741	lytic transglycosylase activity
JHT10_21150	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_21195	COG0175	sulfate reduction
JHT10_21200	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JHT10_21205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JHT10_21225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHT10_21230	COG0735	belongs to the Fur family
JHT10_21240	COG0166	Belongs to the GPI family
JHT10_21245	COG0432	Pfam Uncharacterised protein family UPF0047
JHT10_21255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHT10_21270	COG0359	binds to the 23S rRNA
JHT10_21280	COG2965	DNA replication, synthesis of RNA primer
JHT10_21285	COG0360	Binds together with S18 to 16S ribosomal RNA
JHT10_21290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JHT10_21295	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JHT10_21305	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JHT10_21310	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JHT10_21340	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JHT10_21350	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JHT10_21350	COG0678	peroxiredoxin activity
JHT10_21360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JHT10_21360	COG0165	Argininosuccinate lyase
JHT10_21365	COG0137	argininosuccinate synthase activity
JHT10_21370	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JHT10_21375	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JHT10_21380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JHT10_21385	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JHT10_21395	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JHT10_21400	COG0527	aspartate kinase activity
JHT10_21400	COG0460	homoserine dehydrogenase
JHT10_21405	COG0626	cystathionine gamma-synthase activity
JHT10_21415	COG0281	malic enzyme
JHT10_21425	COG2906	2 iron, 2 sulfur cluster binding
JHT10_21430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JHT10_21435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JHT10_21440	COG0049	tRNA binding
JHT10_21455	COG2923	Belongs to the DsrF TusC family
JHT10_21460	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JHT10_21465	COG2964	Protein conserved in bacteria
JHT10_21470	COG0545	Peptidyl-prolyl cis-trans isomerase
JHT10_21480	COG2900	Belongs to the SlyX family
JHT10_21485	COG1446	asparaginase
JHT10_21490	COG1047	Peptidyl-prolyl cis-trans
JHT10_21505	COG2249	NAD(P)H dehydrogenase (quinone) activity
JHT10_21510	COG0488	(ABC) transporter
JHT10_21520	COG0429	hydrolase of the alpha beta-hydrolase fold
JHT10_21525	COG3089	Belongs to the UPF0270 family
JHT10_21530	COG3954	Phosphoribulokinase
JHT10_21535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHT10_21545	COG1012	belongs to the aldehyde dehydrogenase family
JHT10_21555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JHT10_21560	COG0512	Glutamine amidotransferase of anthranilate synthase
JHT10_21575	COG0180	Tryptophanyl-tRNA synthetase
JHT10_21580	COG0546	phosphoglycolate phosphatase activity
JHT10_21585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHT10_21590	COG0557	exoribonuclease II activity
JHT10_21595	COG1959	2 iron, 2 sulfur cluster binding
JHT10_21600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JHT10_21600	COG1017	nitric oxide dioxygenase activity
JHT10_21605	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
JHT10_21610	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JHT10_21615	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
JHT10_21620	COG0330	HflC and HflK could
JHT10_21625	COG0330	HflC and HflK could
JHT10_21630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JHT10_21640	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JHT10_21645	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JHT10_21655	COG0802	atpase or kinase
JHT10_21660	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JHT10_21730	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JHT10_21735	COG1162	GTPase activity
JHT10_21740	COG0688	phosphatidylethanolamine metabolic process
JHT10_21745	COG0471	metal ion transport
JHT10_21760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JHT10_21765	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHT10_21770	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JHT10_21775	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JHT10_21780	COG1045	serine acetyltransferase
JHT10_21785	COG4942	peptidase
JHT10_21805	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JHT10_21810	COG1053	succinate dehydrogenase
JHT10_21815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JHT10_21820	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JHT10_21825	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JHT10_21835	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JHT10_21840	COG1509	lysine 2,3-aminomutase activity
JHT10_21845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHT10_21860	COG0459	protein refolding
JHT10_21870	COG0534	Mate efflux family protein
JHT10_21875	COG0205	6-phosphofructokinase activity
JHT10_21885	COG3678	ATP-independent chaperone mediated protein folding
JHT10_21890	COG0745	RESPONSE REGULATOR receiver
JHT10_21895	COG2205	protein histidine kinase activity
JHT10_21905	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JHT10_21910	COG3030	protein affecting phage T7 exclusion by the F plasmid
JHT10_21915	COG1027	Aspartate ammonia-lyase
JHT10_21920	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JHT10_21925	COG4232	protein-disulfide reductase activity
JHT10_21935	COG3263	regulation of cellular component size
JHT10_21945	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHT10_21965	COG2205	protein histidine kinase activity
JHT10_21965	COG2198	Histidine kinase
JHT10_21965	COG0784	Response regulator, receiver
JHT10_21970	COG2814	Major facilitator Superfamily
JHT10_21985	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JHT10_21990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JHT10_21995	COG0511	ligase activity, forming carbon-carbon bonds
JHT10_22000	COG0439	Biotin carboxylase
JHT10_22005	COG2264	protein methyltransferase activity
JHT10_22010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHT10_22015	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JHT10_22020	COG2814	Major facilitator Superfamily
JHT10_22025	COG0488	(ABC) transporter
JHT10_22030	COG3706	GGDEF domain
JHT10_22040	COG3335	DDE superfamily endonuclease
JHT10_22070	COG3437	response regulator, receiver
JHT10_22080	COG3394	polysaccharide catabolic process
JHT10_22085	COG1486	melibiose metabolic process
JHT10_22090	COG1447	Phosphotransferase system cellobiose-specific component IIA
JHT10_22095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JHT10_22100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JHT10_22105	COG0726	polysaccharide deacetylase
JHT10_22205	COG1028	Short-chain dehydrogenase reductase Sdr
JHT10_22220	COG0795	lipopolysaccharide-transporting ATPase activity
JHT10_22225	COG0795	lipopolysaccharide-transporting ATPase activity
JHT10_22230	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JHT10_22235	COG2927	DNA polymerase III (CHI subunit)
JHT10_22240	COG0525	valine-tRNA ligase activity
JHT10_22265	COG2235	arginine
JHT10_22270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JHT10_22280	COG0540	Belongs to the ATCase OTCase family
JHT10_22285	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
JHT10_22290	COG0251	oxidation-reduction process
JHT10_22295	COG0204	Acyl-transferase
JHT10_22300	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JHT10_22305	COG5007	Belongs to the BolA IbaG family
JHT10_22315	COG2854	intermembrane phospholipid transfer
JHT10_22320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JHT10_22325	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JHT10_22330	COG1127	ABC transporter
JHT10_22340	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JHT10_22340	COG0517	IMP dehydrogenase activity
JHT10_22350	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JHT10_22355	COG1137	ATPase activity
JHT10_22365	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JHT10_22370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_22375	COG1660	Displays ATPase and GTPase activities
JHT10_22380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHT10_22385	COG2239	Acts as a magnesium transporter
JHT10_22390	COG0312	modulator of DNA gyrase
JHT10_22395	COG3028	Belongs to the UPF0307 family
JHT10_22400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHT10_22405	COG0564	pseudouridine synthase activity
JHT10_22415	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JHT10_22420	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JHT10_22425	COG0312	modulator of DNA gyrase
JHT10_22430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JHT10_22435	COG3164	Protein of unknown function
JHT10_22445	COG0424	maF-like protein
JHT10_22450	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JHT10_22455	COG1792	Involved in formation and maintenance of cell shape
JHT10_22460	COG1077	Cell shape determining protein MreB Mrl
JHT10_22505	COG1459	type II secretion system
JHT10_22510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHT10_22520	COG3409	Peptidoglycan-binding domain 1 protein
JHT10_22520	COG3267	Type II secretory pathway component ExeA
JHT10_22545	COG2200	EAL domain
JHT10_22545	COG2199	diguanylate cyclase activity
JHT10_22550	COG0629	single-stranded DNA binding
JHT10_22565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JHT10_22575	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JHT10_22580	COG0527	aspartate kinase activity
JHT10_22585	COG1410	methionine synthase
JHT10_22585	COG0646	methionine synthase
JHT10_22600	COG3335	DDE superfamily endonuclease
JHT10_22655	COG1982	Orn Lys Arg decarboxylase major
JHT10_22660	COG0531	amino acid
JHT10_22670	COG3710	Transcriptional regulator
JHT10_22675	COG0789	Transcriptional regulator
JHT10_22680	COG0138	bifunctional purine biosynthesis protein purh
JHT10_22685	COG0151	Belongs to the GarS family
JHT10_22700	COG1253	flavin adenine dinucleotide binding
JHT10_22710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JHT10_22715	COG1573	uracil-dna glycosylase
JHT10_22720	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JHT10_22735	COG2816	NAD+ diphosphatase activity
JHT10_22740	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
JHT10_22745	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHT10_22750	COG0085	RNA polymerase activity
JHT10_22755	COG0222	ribosome binding
JHT10_22760	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JHT10_22765	COG0081	regulation of translation
JHT10_22770	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JHT10_22775	COG0250	Participates in transcription elongation, termination and antitermination
JHT10_22780	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JHT10_22785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JHT10_22820	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JHT10_22830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHT10_22860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JHT10_22870	COG4206	TonB-dependent receptor
JHT10_22890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JHT10_22895	COG0534	Mate efflux family protein
JHT10_22900	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JHT10_22905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JHT10_22910	COG2937	Belongs to the GPAT DAPAT family
JHT10_22915	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JHT10_22920	COG3161	chorismate lyase activity
JHT10_22925	COG1580	Controls the rotational direction of flagella during chemotaxis
JHT10_22930	COG0705	Rhomboid family
JHT10_22935	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHT10_22945	COG2177	Part of the ABC transporter FtsEX involved in
JHT10_22950	COG2884	Cell division ATP-binding protein ftsE
JHT10_22955	COG0552	protein localization to endoplasmic reticulum
JHT10_22960	COG0742	ribosomal rna small subunit methyltransferase
JHT10_22970	COG2095	MarC family integral membrane protein
JHT10_23020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JHT10_23025	COG0640	Transcriptional regulator
JHT10_23030	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JHT10_23035	COG1280	lysine exporter protein (LysE YggA)
JHT10_23040	COG2267	carboxylic ester hydrolase activity
JHT10_23045	COG0561	phosphatase activity
JHT10_23060	COG3148	PFAM DTW domain containing protein
JHT10_23065	COG3287	FIST C domain
JHT10_23065	COG2199	diguanylate cyclase activity
JHT10_23065	COG2200	EAL domain
JHT10_23070	COG1011	Hydrolase
JHT10_23075	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JHT10_23085	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JHT10_23090	COG0019	diaminopimelate decarboxylase activity
JHT10_23100	COG1965	Belongs to the frataxin family
JHT10_23105	COG3072	Adenylate cyclase
JHT10_23110	COG0181	hydroxymethylbilane synthase activity
JHT10_23115	COG1587	Uroporphyrinogen-III synthase
JHT10_23120	COG2959	enzyme of heme biosynthesis
JHT10_23125	COG3071	HemY protein
JHT10_23195	COG0633	Ferredoxin
JHT10_23200	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JHT10_23215	COG3118	belongs to the thioredoxin family
JHT10_23220	COG0513	Belongs to the DEAD box helicase family
JHT10_23225	COG0248	Ppx GppA phosphatase
JHT10_23230	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JHT10_23240	COG0514	ATP-dependent DNA helicase (RecQ)
JHT10_23245	COG2962	Rard protein
JHT10_23255	COG1280	lysine exporter protein (LysE YggA)
JHT10_23260	COG0405	Gamma-glutamyltransferase
JHT10_23265	COG0210	DNA helicase
JHT10_23275	COG3220	belongs to the UPF0276 family
JHT10_23305	COG0006	proline dipeptidase activity
JHT10_23305	COG0006	proline dipeptidase activity
JHT10_23315	COG2022	thiamine diphosphate biosynthetic process
JHT10_23320	COG2104	thiamine diphosphate biosynthetic process
JHT10_23325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JHT10_23335	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JHT10_23340	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JHT10_23355	COG3335	DDE superfamily endonuclease
JHT10_23395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JHT10_23405	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JHT10_23410	COG0408	coproporphyrinogen oxidase activity
JHT10_23415	COG0009	L-threonylcarbamoyladenylate synthase
JHT10_23420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JHT10_23425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JHT10_23430	COG0551	DNA topoisomerase type I activity
JHT10_23435	COG2922	Belongs to the Smg family
JHT10_23440	COG0758	DNA mediated transformation
JHT10_23450	COG0242	peptide deformylase activity
JHT10_23455	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JHT10_23460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JHT10_23460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JHT10_23465	COG0569	domain protein
JHT10_23470	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHT10_23480	COG1272	protein, Hemolysin III
JHT10_23485	COG4326	sporulation control protein
JHT10_23490	COG3084	Protein conserved in bacteria
JHT10_23500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JHT10_23505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHT10_23510	COG0204	Acyl-transferase
JHT10_23520	COG0606	chelatase, subunit chli
JHT10_23530	COG3978	acetolactate synthase activity
JHT10_23535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JHT10_23540	COG0129	dihydroxy-acid dehydratase activity
JHT10_23550	COG0583	DNA-binding transcription factor activity
JHT10_23555	COG2814	Major facilitator Superfamily
JHT10_23560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHT10_23565	COG0765	amino acid transport
JHT10_23570	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JHT10_23575	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JHT10_23580	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JHT10_23585	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JHT10_23590	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JHT10_23595	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JHT10_23610	COG0356	it plays a direct role in the translocation of protons across the membrane
JHT10_23615	COG3312	ion transport
JHT10_23620	COG1475	DNA binding
JHT10_23625	COG1192	Involved in chromosome partitioning
JHT10_23630	COG0357	Ribosomal RNA small subunit methyltransferase G
JHT10_23635	COG0445	tRNA wobble uridine modification
JHT10_23640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JHT10_23645	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JHT10_23650	COG0706	membrane insertase activity
JHT10_23660	COG0594	ribonuclease P activity
JHT10_23670	COG1126	abc transporter atp-binding protein
JHT10_23705	COG4932	domain protein
JHT10_23705	COG5492	domain, Protein
JHT10_23895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHT10_24010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHT10_24040	COG2948	multi-organism process
JHT10_24055	COG3701	Conjugal transfer protein
JHT10_24065	COG4962	Type ii secretion system protein e
JHT10_24075	COG3451	type IV secretory pathway VirB4