locus-tag	class	description
JHS79_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JHS79_00010	COG0592	DNA-directed DNA polymerase activity
JHS79_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JHS79_00020	COG0187	DNA topoisomerase II activity
JHS79_00030	COG0071	Belongs to the small heat shock protein (HSP20) family
JHS79_00035	COG3977	Valine--pyruvate aminotransferase
JHS79_00040	COG0366	Alpha amylase catalytic
JHS79_00045	COG0751	glycine-tRNA ligase activity
JHS79_00050	COG0752	glycyl-tRNA synthetase alpha subunit
JHS79_00055	COG2119	membrane
JHS79_00065	COG0425	Belongs to the sulfur carrier protein TusA family
JHS79_00080	COG0604	alcohol dehydrogenase
JHS79_00085	COG0183	Belongs to the thiolase family
JHS79_00090	COG1024	Enoyl-CoA hydratase
JHS79_00090	COG1250	3-hydroxyacyl-CoA dehydrogenase
JHS79_00095	COG1739	Uncharacterized protein family UPF0029
JHS79_00100	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHS79_00140	COG0583	DNA-binding transcription factor activity
JHS79_00145	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JHS79_00150	COG2960	long-chain fatty acid transporting porin activity
JHS79_00155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHS79_00160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHS79_00210	COG4172	Belongs to the ABC transporter superfamily
JHS79_00215	COG0747	negative chemotaxis
JHS79_00220	COG0601	transmembrane transport
JHS79_00225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHS79_00260	COG1609	Transcriptional regulator
JHS79_00265	COG0583	DNA-binding transcription factor activity
JHS79_00280	COG0129	dihydroxy-acid dehydratase activity
JHS79_00285	COG3265	gluconokinase activity
JHS79_00290	COG2610	gluconate transmembrane transporter activity
JHS79_00295	COG0800	Aldolase
JHS79_00300	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JHS79_00305	COG0583	DNA-binding transcription factor activity
JHS79_00310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JHS79_00315	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JHS79_00320	COG0339	signal peptide processing
JHS79_00325	COG1522	sequence-specific DNA binding
JHS79_00330	COG5002	protein histidine kinase activity
JHS79_00330	COG5001	Diguanylate cyclase
JHS79_00335	COG0742	ribosomal rna small subunit methyltransferase
JHS79_00350	COG0589	response to stress
JHS79_00355	COG1528	Iron-storage protein
JHS79_00365	COG2081	HI0933 family
JHS79_00375	COG2823	Periplasmic or secreted lipoprotein
JHS79_00425	COG0628	permease
JHS79_00440	COG1322	Protein conserved in bacteria
JHS79_00445	COG2226	methyltransferase
JHS79_00450	COG3165	ubiquinone biosynthetic process from chorismate
JHS79_00455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JHS79_00460	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JHS79_00465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JHS79_00470	COG0805	protein transport
JHS79_00475	COG0084	hydrolase, TatD family'
JHS79_00495	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHS79_00495	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHS79_00500	COG0218	Necessary for normal cell division and for the maintenance of normal septation
JHS79_00535	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JHS79_00545	COG2204	response regulator
JHS79_00550	COG3852	Histidine kinase
JHS79_00560	COG0174	glutamine synthetase
JHS79_00565	COG1217	gtp-binding protein TYPA
JHS79_00580	COG1295	ribonuclease BN
JHS79_00585	COG1490	D-aminoacyl-tRNA deacylase activity
JHS79_00590	COG0456	acetyltransferase
JHS79_00600	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JHS79_00605	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JHS79_00610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JHS79_00615	COG3031	protein transport across the cell outer membrane
JHS79_00625	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHS79_00630	COG1459	type II secretion system
JHS79_00635	COG2165	general secretion pathway protein
JHS79_00640	COG2165	general secretion pathway protein
JHS79_00645	COG2165	general secretion pathway protein
JHS79_00650	COG4795	General secretion pathway protein
JHS79_00655	COG3156	type II secretion system protein K
JHS79_00660	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JHS79_00665	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
JHS79_00675	COG1218	3'(2'),5'-bisphosphate nucleotidase
JHS79_00680	COG0494	nUDIX hydrolase
JHS79_00685	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
JHS79_00685	COG0316	Belongs to the HesB IscA family
JHS79_00690	COG1040	competence protein
JHS79_00695	COG0596	Alpha beta hydrolase
JHS79_00705	COG2183	response to ionizing radiation
JHS79_00715	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHS79_00735	COG2233	PERMEase
JHS79_00740	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JHS79_00745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHS79_00750	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JHS79_00755	COG1758	RNA polymerase activity
JHS79_00760	COG0194	GDP metabolic process
JHS79_00775	COG0848	biopolymer transport protein
JHS79_00780	COG0811	peptide transport
JHS79_00800	COG4174	ABC transporter (Permease)
JHS79_00805	COG4239	(ABC) transporter, permease
JHS79_00810	COG0747	negative chemotaxis
JHS79_00815	COG0444	Belongs to the ABC transporter superfamily
JHS79_00820	COG4608	Belongs to the ABC transporter superfamily
JHS79_00830	COG1561	YicC-like family, N-terminal region
JHS79_00835	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
JHS79_00840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JHS79_00845	COG1560	Kdo2-lipid A biosynthetic process
JHS79_00850	COG1309	transcriptional regulator
JHS79_00855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JHS79_00865	COG2003	Belongs to the UPF0758 family
JHS79_00870	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JHS79_00885	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JHS79_00895	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JHS79_00905	COG0463	Glycosyl transferase, family 2
JHS79_00910	COG0859	PFAM glycosyl transferase family 9
JHS79_00915	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JHS79_00920	COG3642	lipopolysaccharide core region biosynthetic process
JHS79_00940	COG1045	serine acetyltransferase
JHS79_00945	COG1086	Polysaccharide biosynthesis protein
JHS79_00950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JHS79_00955	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JHS79_00960	COG2089	acid synthase
JHS79_00970	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JHS79_00975	COG1083	cytidylyl-transferase
JHS79_00985	COG1519	Transferase
JHS79_00990	COG0859	PFAM glycosyl transferase family 9
JHS79_00995	COG1560	Kdo2-lipid A biosynthetic process
JHS79_01005	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHS79_01025	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JHS79_01030	COG2895	sulfate adenylyltransferase (ATP) activity
JHS79_01040	COG0529	Catalyzes the synthesis of activated sulfate
JHS79_01045	COG0175	sulfate reduction
JHS79_01060	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHS79_01065	COG1459	type II secretion system
JHS79_01085	COG3156	type II secretion system protein K
JHS79_01115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JHS79_01160	COG1088	dTDP-glucose 4,6-dehydratase activity
JHS79_01185	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JHS79_01190	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JHS79_01195	COG0517	IMP dehydrogenase activity
JHS79_01195	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JHS79_01200	COG0438	transferase activity, transferring glycosyl groups
JHS79_01200	COG1216	Glycosyl transferase, family 2
JHS79_01230	COG0471	metal ion transport
JHS79_01230	COG3273	potassium ion transport
JHS79_01240	COG1216	Glycosyl transferase, family 2
JHS79_01240	COG0438	transferase activity, transferring glycosyl groups
JHS79_01265	COG0149	triose-phosphate isomerase activity
JHS79_01290	COG1494	fructose-1,6-bisphosphatase
JHS79_01295	COG3074	FtsZ-dependent cytokinesis
JHS79_01300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JHS79_01305	COG1575	Belongs to the MenA family. Type 1 subfamily
JHS79_01310	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JHS79_01315	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JHS79_01325	COG1609	Transcriptional regulator
JHS79_01330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JHS79_01335	COG0254	rRNA binding
JHS79_01345	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
JHS79_01350	COG0088	Forms part of the polypeptide exit tunnel
JHS79_01360	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JHS79_01365	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JHS79_01370	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
JHS79_01375	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JHS79_01385	COG0255	Belongs to the universal ribosomal protein uL29 family
JHS79_01390	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JHS79_01395	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JHS79_01400	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
JHS79_01405	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
JHS79_01410	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JHS79_01415	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JHS79_01420	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JHS79_01435	COG1841	ribosomal large subunit assembly
JHS79_01440	COG0200	Binds to the 23S rRNA
JHS79_01445	COG0201	protein transport
JHS79_01450	COG0257	Belongs to the bacterial ribosomal protein bL36 family
JHS79_01455	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JHS79_01460	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JHS79_01470	COG0202	RNA polymerase activity
JHS79_01475	COG0203	ribosomal protein L17
JHS79_01485	COG0545	Peptidyl-prolyl cis-trans isomerase
JHS79_01495	COG2153	protein acetylation
JHS79_01500	COG0513	Belongs to the DEAD box helicase family
JHS79_01510	COG0737	Belongs to the 5'-nucleotidase family
JHS79_01515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JHS79_01515	COG1648	precorrin-2 dehydrogenase activity
JHS79_01520	COG0175	sulfate reduction
JHS79_01525	COG2895	sulfate adenylyltransferase (ATP) activity
JHS79_01530	COG3273	potassium ion transport
JHS79_01530	COG0471	metal ion transport
JHS79_01535	COG0529	Catalyzes the synthesis of activated sulfate
JHS79_01555	COG4181	ATPase activity
JHS79_01570	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JHS79_01580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHS79_01585	COG0729	surface antigen
JHS79_01595	COG2105	PFAM AIG2 family protein
JHS79_01605	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JHS79_01610	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
JHS79_01615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JHS79_01620	COG0163	prenyltransferase activity
JHS79_01625	COG4143	(ABC) transporter
JHS79_01630	COG1178	ABC-type Fe3 transport system permease component
JHS79_01635	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
JHS79_01650	COG2358	TRAP transporter, solute receptor (TAXI family
JHS79_01660	COG0039	L-malate dehydrogenase activity
JHS79_01670	COG0142	geranyltranstransferase activity
JHS79_01675	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JHS79_01685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JHS79_01690	COG2966	Psort location CytoplasmicMembrane, score
JHS79_01705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JHS79_01710	COG2967	ApaG domain
JHS79_01715	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JHS79_01720	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
JHS79_01725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JHS79_01730	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
JHS79_01735	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JHS79_01745	COG0066	3-isopropylmalate dehydratase activity
JHS79_01750	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JHS79_01755	COG0473	3-isopropylmalate dehydrogenase activity
JHS79_01760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JHS79_01780	COG0583	DNA-binding transcription factor activity
JHS79_01785	COG1022	Amp-dependent synthetase and ligase
JHS79_01790	COG0028	Belongs to the TPP enzyme family
JHS79_01795	COG0440	acetolactate synthase activity
JHS79_01810	COG0469	pyruvate kinase activity
JHS79_01815	COG1349	DNA-binding transcription factor activity
JHS79_01820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JHS79_01835	COG5002	protein histidine kinase activity
JHS79_01840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHS79_01845	COG3722	fumarate hydratase activity
JHS79_01850	COG0246	Mannitol dehydrogenase
JHS79_01855	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHS79_01855	COG2213	PTS system mannitol-specific
JHS79_01885	COG1464	Belongs to the NlpA lipoprotein family
JHS79_01925	COG2264	protein methyltransferase activity
JHS79_02020	COG0358	DNA primase activity
JHS79_02025	COG1610	YqeY-like protein
JHS79_02030	COG0828	Belongs to the bacterial ribosomal protein bS21 family
JHS79_02035	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JHS79_02040	COG0596	Alpha beta hydrolase
JHS79_02045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JHS79_02050	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JHS79_02055	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JHS79_02060	COG1968	undecaprenyl-diphosphatase activity
JHS79_02065	COG0617	tRNA 3'-terminal CCA addition
JHS79_02070	COG3267	Type II secretory pathway component ExeA
JHS79_02070	COG3409	Peptidoglycan-binding domain 1 protein
JHS79_02080	COG4991	sh3 domain protein
JHS79_02085	COG0306	phosphate transporter
JHS79_02090	COG1392	Phosphate transport regulator
JHS79_02095	COG3025	triphosphatase activity
JHS79_02110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JHS79_02115	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
JHS79_02115	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
JHS79_02120	COG1538	Outer membrane efflux protein
JHS79_02125	COG0494	nUDIX hydrolase
JHS79_02130	COG3151	Protein conserved in bacteria
JHS79_02140	COG3150	esterase
JHS79_02150	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JHS79_02155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JHS79_02165	COG3105	Protein conserved in bacteria
JHS79_02170	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JHS79_02175	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JHS79_02180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JHS79_02185	COG0723	plastoquinol--plastocyanin reductase activity
JHS79_02190	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JHS79_02195	COG2857	Cytochrome c1
JHS79_02200	COG0625	glutathione transferase activity
JHS79_02205	COG2969	positive regulation of protein catabolic process
JHS79_02210	COG2823	Periplasmic or secreted lipoprotein
JHS79_02215	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JHS79_02220	COG0792	nuclease activity
JHS79_02230	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JHS79_02240	COG0275	rRNA processing
JHS79_02245	COG3116	cell division
JHS79_02250	COG0768	penicillin binding
JHS79_02255	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JHS79_02260	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JHS79_02265	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JHS79_02270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JHS79_02275	COG0772	Belongs to the SEDS family
JHS79_02280	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JHS79_02285	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JHS79_02290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JHS79_02295	COG0849	cell division
JHS79_02300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JHS79_02305	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
JHS79_02315	COG0653	protein targeting
JHS79_02320	COG0494	nUDIX hydrolase
JHS79_02325	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
JHS79_02330	COG0505	Belongs to the CarA family
JHS79_02335	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JHS79_02350	COG0730	response to heat
JHS79_02365	COG0583	DNA-binding transcription factor activity
JHS79_02370	COG2860	membrane
JHS79_02375	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JHS79_02385	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JHS79_02395	COG0493	'glutamate synthase
JHS79_02400	COG0067	glutamate synthase
JHS79_02400	COG0069	glutamate synthase activity
JHS79_02400	COG0070	glutamate synthase
JHS79_02410	COG0069	glutamate synthase activity
JHS79_02410	COG0070	glutamate synthase
JHS79_02410	COG0067	glutamate synthase
JHS79_02415	COG1242	4 iron, 4 sulfur cluster binding
JHS79_02420	COG5001	Diguanylate cyclase
JHS79_02420	COG2203	Gaf domain
JHS79_02420	COG3706	GGDEF domain
JHS79_02420	COG4251	negative regulation of phosphorylation
JHS79_02425	COG5002	protein histidine kinase activity
JHS79_02425	COG0784	Response regulator, receiver
JHS79_02425	COG2198	Histidine kinase
JHS79_02435	COG0745	RESPONSE REGULATOR receiver
JHS79_02445	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JHS79_02460	COG0083	homoserine kinase activity
JHS79_02465	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JHS79_02470	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
JHS79_02475	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JHS79_02480	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
JHS79_02495	COG1115	amino acid carrier protein
JHS79_02500	COG3022	response to hydroperoxide
JHS79_02505	COG0513	Belongs to the DEAD box helicase family
JHS79_02510	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
JHS79_02520	COG0716	FMN binding
JHS79_02525	COG4974	Belongs to the 'phage' integrase family
JHS79_02530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHS79_02535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JHS79_02545	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
JHS79_02560	COG0667	Aldo Keto reductase
JHS79_02570	COG3066	DNA modification
JHS79_02575	COG0494	nUDIX hydrolase
JHS79_02585	COG0730	response to heat
JHS79_02590	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JHS79_02595	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
JHS79_02605	COG1283	sodium-dependent phosphate transmembrane transporter activity
JHS79_02610	COG0583	DNA-binding transcription factor activity
JHS79_02615	COG0640	Transcriptional regulator
JHS79_02620	COG0268	Binds directly to 16S ribosomal RNA
JHS79_02625	COG0728	peptidoglycan biosynthetic process
JHS79_02630	COG0196	riboflavin kinase activity
JHS79_02635	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JHS79_02640	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
JHS79_02645	COG1047	Peptidyl-prolyl cis-trans
JHS79_02650	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JHS79_02655	COG3279	Response regulator of the LytR AlgR family
JHS79_02660	COG3275	phosphorelay sensor kinase activity
JHS79_02665	COG1966	Carbon starvation protein
JHS79_02680	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JHS79_02685	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JHS79_02690	COG1472	Belongs to the glycosyl hydrolase 3 family
JHS79_02695	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JHS79_02700	COG0287	Prephenate dehydrogenase
JHS79_02700	COG1605	Chorismate mutase
JHS79_02705	COG0739	heme binding
JHS79_02715	COG0488	(ABC) transporter
JHS79_02725	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
JHS79_02730	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
JHS79_02735	COG1605	Chorismate mutase
JHS79_02735	COG0077	Prephenate dehydratase
JHS79_02740	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JHS79_02745	COG0741	lytic transglycosylase activity
JHS79_02750	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHS79_02755	COG0564	pseudouridine synthase activity
JHS79_02765	COG0542	response to heat
JHS79_02820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JHS79_02825	COG0826	peptidase U32
JHS79_02830	COG2974	May be involved in recombination
JHS79_02835	COG0745	RESPONSE REGULATOR receiver
JHS79_02840	COG5002	protein histidine kinase activity
JHS79_02850	COG0248	Ppx GppA phosphatase
JHS79_02855	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JHS79_02865	COG0581	inorganic phosphate transmembrane transporter activity
JHS79_02870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JHS79_02875	COG0704	Plays a role in the regulation of phosphate uptake
JHS79_02885	COG3142	Participates in the control of copper homeostasis
JHS79_02890	COG0450	alkyl hydroperoxide reductase
JHS79_02895	COG0583	DNA-binding transcription factor activity
JHS79_02900	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JHS79_02910	COG0517	IMP dehydrogenase activity
JHS79_02920	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JHS79_02925	COG0343	queuine tRNA-ribosyltransferase activity
JHS79_02930	COG1862	Preprotein translocase
JHS79_02935	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHS79_02940	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHS79_02945	COG0483	inositol monophosphate 1-phosphatase activity
JHS79_02960	COG1104	cysteine desulfurase activity
JHS79_02965	COG0822	iron-sulfur transferase activity
JHS79_02975	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
JHS79_02980	COG0443	Heat shock 70 kDa protein
JHS79_02985	COG0633	Ferredoxin
JHS79_02990	COG2975	iron-sulfur cluster assembly
JHS79_02995	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JHS79_03000	COG0105	UTP biosynthetic process
JHS79_03005	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JHS79_03015	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JHS79_03020	COG0124	histidyl-tRNA synthetase
JHS79_03025	COG2976	Protein conserved in bacteria
JHS79_03030	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHS79_03035	COG1160	GTP binding
JHS79_03050	COG1570	exodeoxyribonuclease VII activity
JHS79_03055	COG0517	IMP dehydrogenase activity
JHS79_03055	COG0516	GMP reductase activity
JHS79_03060	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JHS79_03060	COG0519	Catalyzes the synthesis of GMP from XMP
JHS79_03065	COG0582	viral genome integration into host DNA
JHS79_03170	COG1757	Na H antiporter
JHS79_03180	COG1584	GPR1 FUN34 yaaH family protein
JHS79_03190	COG1115	amino acid carrier protein
JHS79_03220	COG2873	o-acetylhomoserine
JHS79_03225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JHS79_03245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JHS79_03245	COG3153	acetyltransferase
JHS79_03250	COG0583	DNA-binding transcription factor activity
JHS79_03355	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
JHS79_03385	COG0582	viral genome integration into host DNA
JHS79_03395	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JHS79_03400	COG2867	negative regulation of translational initiation
JHS79_03405	COG2914	Belongs to the UPF0125 (RnfH) family
JHS79_03410	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JHS79_03415	COG0497	DNA recombination
JHS79_03425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JHS79_03430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JHS79_03440	COG0443	Heat shock 70 kDa protein
JHS79_03445	COG0484	heat shock protein binding
JHS79_03475	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JHS79_03490	COG2027	D-alanyl-D-alanine carboxypeptidase
JHS79_03495	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JHS79_03500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHS79_03505	COG1534	Rna-binding protein
JHS79_03510	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
JHS79_03515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JHS79_03520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JHS79_03525	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHS79_03530	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JHS79_03545	COG0779	Required for maturation of 30S ribosomal subunits
JHS79_03550	COG0195	Participates in both transcription termination and antitermination
JHS79_03555	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JHS79_03560	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JHS79_03565	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JHS79_03570	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JHS79_03575	COG1185	polyribonucleotide nucleotidyltransferase activity
JHS79_03590	COG0534	Mate efflux family protein
JHS79_03595	COG0826	peptidase U32
JHS79_03600	COG0826	peptidase U32
JHS79_03610	COG3154	lipid carrier protein
JHS79_03615	COG3153	acetyltransferase
JHS79_03635	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JHS79_03645	COG0084	hydrolase, TatD family'
JHS79_03650	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHS79_03655	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JHS79_03660	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
JHS79_03665	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JHS79_03670	COG0813	purine-nucleoside phosphorylase activity
JHS79_03680	COG0560	Phosphoserine phosphatase
JHS79_03690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JHS79_03695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JHS79_03700	COG0583	DNA-binding transcription factor activity
JHS79_03710	COG1022	Amp-dependent synthetase and ligase
JHS79_03715	COG2169	Transcriptional regulator
JHS79_03740	COG4964	Belongs to the GSP D family
JHS79_03800	COG0583	DNA-binding transcription factor activity
JHS79_03805	COG0531	amino acid
JHS79_03810	COG2731	YhcH YjgK YiaL family protein
JHS79_03815	COG3250	beta-galactosidase activity
JHS79_03820	COG1609	Transcriptional regulator
JHS79_03825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JHS79_03835	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JHS79_03840	COG2017	converts alpha-aldose to the beta-anomer
JHS79_03855	COG2211	Major facilitator Superfamily
JHS79_03860	COG1609	Transcriptional regulator
JHS79_03865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHS79_03880	COG0598	Magnesium transport protein CorA
JHS79_03885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JHS79_03890	COG1349	DNA-binding transcription factor activity
JHS79_03895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JHS79_03900	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JHS79_03905	COG2271	Major facilitator Superfamily
JHS79_03910	COG0584	glycerophosphoryl diester phosphodiesterase
JHS79_03915	COG2171	N-acyltransferase activity
JHS79_03930	COG3141	response to X-ray
JHS79_03950	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JHS79_03955	COG1074	ATP-dependent DNA helicase activity
JHS79_03960	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JHS79_03980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JHS79_03980	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JHS79_03990	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
JHS79_03995	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JHS79_04000	COG2166	iron-sulfur cluster assembly
JHS79_04005	COG3706	GGDEF domain
JHS79_04010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JHS79_04015	COG0693	protein deglycase activity
JHS79_04020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
JHS79_04045	COG1595	DNA-templated transcription, initiation
JHS79_04065	COG3056	Lipoprotein
JHS79_04070	COG2813	Specifically methylates the guanine in position
JHS79_04075	COG0271	Belongs to the BolA IbaG family
JHS79_04080	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHS79_04085	COG1805	sodium ion transport
JHS79_04090	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHS79_04095	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHS79_04100	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
JHS79_04105	COG2871	sodium ion transport
JHS79_04110	COG1477	protein flavinylation
JHS79_04125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JHS79_04130	COG0514	ATP-dependent DNA helicase (RecQ)
JHS79_04135	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHS79_04150	COG0733	neurotransmitter:sodium symporter activity
JHS79_04170	COG0442	prolyl-tRNA aminoacylation
JHS79_04175	COG1720	tRNA m6t6A37 methyltransferase activity
JHS79_04180	COG0254	rRNA binding
JHS79_04190	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
JHS79_04195	COG1671	Belongs to the UPF0178 family
JHS79_04220	COG3098	single-species biofilm formation
JHS79_04225	COG0564	pseudouridine synthase activity
JHS79_04235	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
JHS79_04240	COG0024	Methionine aminopeptidase
JHS79_04245	COG0052	Belongs to the universal ribosomal protein uS2 family
JHS79_04250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JHS79_04255	COG0528	UMP kinase activity
JHS79_04260	COG0233	cytoplasmic translational termination
JHS79_04265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JHS79_04270	COG0575	Belongs to the CDS family
JHS79_04275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JHS79_04280	COG0750	zinc metalloprotease
JHS79_04290	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
JHS79_04295	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHS79_04300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JHS79_04305	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHS79_04310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHS79_04315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JHS79_04320	COG0587	DNA-directed DNA polymerase activity
JHS79_04325	COG0825	malonyl-CoA metabolic process
JHS79_04330	COG0037	tRNA processing
JHS79_04340	COG0347	Belongs to the P(II) protein family
JHS79_04345	COG3021	interspecies interaction between organisms
JHS79_04355	COG1388	LysM domain
JHS79_04355	COG0741	lytic transglycosylase activity
JHS79_04360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JHS79_04365	COG2226	methyltransferase
JHS79_04370	COG0328	RNA-DNA hybrid ribonuclease activity
JHS79_04375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JHS79_04400	COG1960	acyl-CoA dehydrogenase activity
JHS79_04405	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
JHS79_04410	COG0121	glutamine amidotransferase
JHS79_04415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JHS79_04420	COG1121	(ABC) transporter
JHS79_04425	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
JHS79_04430	COG4977	sequence-specific DNA binding
JHS79_04435	COG1918	ferrous iron import across plasma membrane
JHS79_04455	COG0018	arginyl-trna synthetase
JHS79_04460	COG3102	Protein conserved in bacteria
JHS79_04465	COG0788	formyltetrahydrofolate deformylase activity
JHS79_04470	COG1199	ATP-dependent helicase activity
JHS79_04475	COG1214	PFAM Peptidase M22, glycoprotease
JHS79_04490	COG2267	carboxylic ester hydrolase activity
JHS79_04495	COG0318	PFAM AMP-dependent synthetase and ligase
JHS79_04500	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
JHS79_04505	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JHS79_04510	COG2894	cell division
JHS79_04515	COG0850	regulation of cytokinetic process
JHS79_04520	COG3100	YcgL domain-containing protein
JHS79_04525	COG2951	lytic endotransglycosylase activity
JHS79_04530	COG0583	DNA-binding transcription factor activity
JHS79_04535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHS79_04540	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JHS79_04560	COG1028	Short-chain dehydrogenase reductase Sdr
JHS79_04570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JHS79_04595	COG2986	histidine ammonia-lyase
JHS79_04600	COG1216	Glycosyl transferase, family 2
JHS79_04605	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JHS79_04620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JHS79_04625	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JHS79_04660	COG1253	flavin adenine dinucleotide binding
JHS79_04665	COG0513	Belongs to the DEAD box helicase family
JHS79_04670	COG0569	domain protein
JHS79_04675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHS79_04690	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JHS79_04695	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JHS79_04700	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
JHS79_04705	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JHS79_04715	COG2204	response regulator
JHS79_04730	COG0544	peptidyl-prolyl cis-trans isomerase activity
JHS79_04740	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JHS79_04745	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JHS79_04750	COG0776	regulation of translation
JHS79_04755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JHS79_04760	COG1555	photosystem II stabilization
JHS79_04775	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JHS79_04780	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
JHS79_04785	COG0436	Aminotransferase
JHS79_04790	COG1169	isochorismate synthase
JHS79_04795	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
JHS79_04800	COG0596	Alpha beta hydrolase
JHS79_04805	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
JHS79_04825	COG2855	membrane
JHS79_04830	COG0477	Major facilitator Superfamily
JHS79_04875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHS79_04880	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHS79_04905	COG1522	sequence-specific DNA binding
JHS79_04915	COG1946	Acyl-CoA thioesterase
JHS79_04920	COG3126	Type III secretion system lipoprotein chaperone (YscW)
JHS79_04975	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JHS79_05035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHS79_05040	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JHS79_05045	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
JHS79_05050	COG0516	GMP reductase activity
JHS79_05050	COG0517	IMP dehydrogenase activity
JHS79_05075	COG0537	adenosine 5'-monophosphoramidase activity
JHS79_05100	COG3150	esterase
JHS79_05105	COG1252	NADH dehydrogenase
JHS79_05120	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JHS79_05130	COG4591	ABC-type transport system involved in lipoprotein release permease component
JHS79_05135	COG1136	(ABC) transporter
JHS79_05140	COG4591	ABC-type transport system involved in lipoprotein release permease component
JHS79_05150	COG2333	competence protein COMEC
JHS79_05150	COG0658	competence protein
JHS79_05155	COG1132	(ABC) transporter
JHS79_05160	COG1663	tetraacyldisaccharide 4'-kinase activity
JHS79_05170	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
JHS79_05175	COG2719	SpoVR family
JHS79_05180	COG2718	Belongs to the UPF0229 family
JHS79_05185	COG2766	serine protein kinase
JHS79_05190	COG3013	Belongs to the UPF0304 family
JHS79_05200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHS79_05210	COG1882	Formate acetyltransferase
JHS79_05255	COG0556	nucleotide-excision repair
JHS79_05260	COG2204	response regulator
JHS79_05265	COG2198	Histidine kinase
JHS79_05270	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JHS79_05275	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JHS79_05280	COG0521	Mo-molybdopterin cofactor biosynthetic process
JHS79_05285	COG0315	cyclic pyranopterin monophosphate synthase activity
JHS79_05290	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
JHS79_05295	COG0314	molybdopterin synthase activity
JHS79_05305	COG0601	transmembrane transport
JHS79_05310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHS79_05315	COG0444	Belongs to the ABC transporter superfamily
JHS79_05325	COG0435	Glutathione S-transferase
JHS79_05335	COG3174	membrane
JHS79_05340	COG0857	belongs to the CobB CobQ family
JHS79_05340	COG0280	phosphate acetyltransferase
JHS79_05345	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHS79_05350	COG3092	negative regulation of chromosome organization
JHS79_05360	COG4120	Belongs to the binding-protein-dependent transport system permease family
JHS79_05365	COG1122	ATPase activity
JHS79_05370	COG0366	Alpha amylase catalytic
JHS79_05380	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JHS79_05390	COG3766	membrane
JHS79_05400	COG0754	glutathionylspermidine amidase activity
JHS79_05410	COG0784	Response regulator, receiver
JHS79_05410	COG5002	protein histidine kinase activity
JHS79_05425	COG0840	transmembrane signaling receptor activity
JHS79_05430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHS79_05435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHS79_05460	COG3568	Endonuclease Exonuclease Phosphatase
JHS79_05475	COG0583	DNA-binding transcription factor activity
JHS79_05485	COG0686	Belongs to the AlaDH PNT family
JHS79_05495	COG1674	ftsk spoiiie
JHS79_05500	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JHS79_05505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JHS79_05510	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JHS79_05525	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JHS79_05530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
JHS79_05535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JHS79_05540	COG0156	8-amino-7-oxononanoate synthase activity
JHS79_05550	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
JHS79_05560	COG0501	Belongs to the peptidase M48B family
JHS79_05570	COG0300	oxidoreductase activity
JHS79_05585	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JHS79_05605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JHS79_05610	COG2915	High frequency lysogenization protein hflD homolog
JHS79_05615	COG0482	sulfurtransferase activity
JHS79_05625	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHS79_05635	COG1757	Na H antiporter
JHS79_05650	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JHS79_05655	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JHS79_05660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JHS79_05665	COG0131	Imidazoleglycerol-phosphate dehydratase
JHS79_05665	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JHS79_05670	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JHS79_05675	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JHS79_05680	COG0107	imidazoleglycerol-phosphate synthase activity
JHS79_05685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JHS79_05685	COG0140	phosphoribosyl-ATP diphosphatase activity
JHS79_05690	COG3012	SEC-C Motif Domain Protein
JHS79_05695	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JHS79_05700	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JHS79_05705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JHS79_05710	COG0215	cysteine-tRNA ligase activity
JHS79_05715	COG1435	thymidine kinase activity
JHS79_05765	COG5002	protein histidine kinase activity
JHS79_05765	COG3850	Histidine kinase
JHS79_05770	COG0745	RESPONSE REGULATOR receiver
JHS79_05775	COG0840	transmembrane signaling receptor activity
JHS79_05780	COG1032	radical SAM domain protein
JHS79_05785	COG5001	Diguanylate cyclase
JHS79_05785	COG3706	GGDEF domain
JHS79_05785	COG4251	negative regulation of phosphorylation
JHS79_05785	COG2203	Gaf domain
JHS79_05800	COG0583	DNA-binding transcription factor activity
JHS79_05805	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
JHS79_05815	COG2350	Protein conserved in bacteria
JHS79_05825	COG2917	probably involved in intracellular septation
JHS79_05845	COG1301	dicarboxylic acid transport
JHS79_05850	COG0318	PFAM AMP-dependent synthetase and ligase
JHS79_05855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHS79_05860	COG0159	tryptophan synthase activity
JHS79_05865	COG0133	tryptophan synthase activity
JHS79_05870	COG0135	phosphoribosylanthranilate isomerase activity
JHS79_05870	COG0134	indole-3-glycerol-phosphate synthase activity
JHS79_05875	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JHS79_05880	COG0512	Glutamine amidotransferase of anthranilate synthase
JHS79_05885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JHS79_05895	COG0613	PHP domain protein
JHS79_05900	COG0009	L-threonylcarbamoyladenylate synthase
JHS79_05910	COG1187	pseudouridine synthase activity
JHS79_05915	COG3099	Belongs to the UPF0263 family
JHS79_05920	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JHS79_05930	COG0417	DNA replication proofreading
JHS79_05935	COG2197	response regulator
JHS79_05940	COG0322	excinuclease ABC activity
JHS79_05980	COG0019	diaminopimelate decarboxylase activity
JHS79_06005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHS79_06010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JHS79_06015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JHS79_06035	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
JHS79_06045	COG0437	4 iron, 4 sulfur cluster binding
JHS79_06050	COG3301	Polysulphide reductase, NrfD
JHS79_06055	COG1138	Cytochrome C-type biogenesis protein
JHS79_06065	COG3088	subunit of a heme lyase
JHS79_06065	COG4235	cytochrome complex assembly
JHS79_06075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JHS79_06100	COG2989	Protein conserved in bacteria
JHS79_06105	COG3108	Peptidase M15
JHS79_06110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JHS79_06125	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JHS79_06150	COG1846	Transcriptional regulator
JHS79_06155	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHS79_06160	COG0840	transmembrane signaling receptor activity
JHS79_06180	COG1448	Aminotransferase
JHS79_06195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHS79_06205	COG0017	Asparaginyl-tRNA synthetase
JHS79_06210	COG0840	transmembrane signaling receptor activity
JHS79_06215	COG0720	synthase
JHS79_06225	COG2200	EAL domain
JHS79_06230	COG1760	l-serine dehydratase
JHS79_06235	COG0814	amino acid
JHS79_06240	COG0494	nUDIX hydrolase
JHS79_06250	COG2205	protein histidine kinase activity
JHS79_06250	COG0784	Response regulator, receiver
JHS79_06255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JHS79_06270	COG3106	COG3106 Predicted ATPase
JHS79_06275	COG3768	UPF0283 membrane protein
JHS79_06285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHS79_06305	COG4735	regulation of single-species biofilm formation
JHS79_06320	COG0582	viral genome integration into host DNA
JHS79_06340	COG5532	Uncharacterized conserved protein (DUF2303)
JHS79_06385	COG4626	Terminase
JHS79_06385	COG1802	Transcriptional regulator
JHS79_06405	COG1403	HNH endonuclease
JHS79_06450	COG3772	lysozyme
JHS79_06480	COG1030	water channel activity
JHS79_06610	COG2226	methyltransferase
JHS79_06775	COG0346	lactoylglutathione lyase activity
JHS79_06875	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JHS79_06955	COG1683	Conserved Protein
JHS79_07255	COG1444	tRNA N-acetyltransferase activity
JHS79_07410	COG0346	lactoylglutathione lyase activity
JHS79_07465	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JHS79_07640	COG0456	acetyltransferase
JHS79_07660	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JHS79_07770	COG0456	acetyltransferase
JHS79_07875	COG0456	acetyltransferase
JHS79_07875	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JHS79_07950	COG1683	Conserved Protein
JHS79_08310	COG2204	response regulator
JHS79_08340	COG1793	dna ligase
JHS79_08350	COG0534	Mate efflux family protein
JHS79_08355	COG0307	riboflavin synthase, alpha
JHS79_08365	COG3001	Fructosamine kinase
JHS79_08370	COG2201	protein-glutamate methylesterase activity
JHS79_08375	COG3706	GGDEF domain
JHS79_08385	COG0791	NLP P60 protein
JHS79_08390	COG0840	transmembrane signaling receptor activity
JHS79_08390	COG3290	protein histidine kinase activity
JHS79_08425	COG3148	PFAM DTW domain containing protein
JHS79_08430	COG1940	carbohydrate kinase activity
JHS79_08460	COG0471	metal ion transport
JHS79_08465	COG4191	Histidine kinase
JHS79_08465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHS79_08475	COG3300	MHYT domain
JHS79_08475	COG5001	Diguanylate cyclase
JHS79_08485	COG1280	lysine exporter protein (LysE YggA)
JHS79_08490	COG1328	CTP reductase activity
JHS79_08495	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHS79_08505	COG0861	Integral membrane protein TerC family
JHS79_08515	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
JHS79_08525	COG0814	amino acid
JHS79_08545	COG1132	(ABC) transporter
JHS79_08550	COG1132	(ABC) transporter
JHS79_08575	COG0443	Heat shock 70 kDa protein
JHS79_08580	COG0443	Heat shock 70 kDa protein
JHS79_08590	COG3706	GGDEF domain
JHS79_08620	COG0243	molybdopterin cofactor binding
JHS79_08625	COG0437	4 iron, 4 sulfur cluster binding
JHS79_08630	COG3302	dmso reductase anchor subunit
JHS79_08645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JHS79_08650	COG1643	Atp-dependent helicase
JHS79_08665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHS79_08675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JHS79_08680	COG1215	transferase activity, transferring glycosyl groups
JHS79_08685	COG0438	transferase activity, transferring glycosyl groups
JHS79_08700	COG0746	molybdenum cofactor guanylyltransferase activity
JHS79_08705	COG3842	ATPase activity
JHS79_08720	COG2204	response regulator
JHS79_08725	COG4191	Histidine kinase
JHS79_08730	COG0488	(ABC) transporter
JHS79_08735	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JHS79_08755	COG3381	protein complex oligomerization
JHS79_08765	COG3383	formate dehydrogenase (NAD+) activity
JHS79_08765	COG0243	molybdopterin cofactor binding
JHS79_08770	COG0437	4 iron, 4 sulfur cluster binding
JHS79_08785	COG3209	COG3209 Rhs family protein
JHS79_08845	COG0004	ammonium transporteR
JHS79_08855	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JHS79_08860	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JHS79_08870	COG1177	transmembrane transport
JHS79_08880	COG3842	ATPase activity
JHS79_08900	COG0037	tRNA processing
JHS79_08905	COG0589	response to stress
JHS79_08910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHS79_08925	COG2217	Heavy metal translocating P-type atpase
JHS79_08935	COG2010	Cytochrome c
JHS79_08950	COG3278	Belongs to the heme-copper respiratory oxidase family
JHS79_08965	COG0784	Response regulator, receiver
JHS79_08965	COG2205	protein histidine kinase activity
JHS79_09015	COG4128	Pfam Zonular occludens toxin
JHS79_09020	COG4453	Protein conserved in bacteria
JHS79_09090	COG3120	sequence-specific DNA binding
JHS79_09095	COG1067	ATP-dependent peptidase activity
JHS79_09100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JHS79_09115	COG0488	(ABC) transporter
JHS79_09125	COG0116	Belongs to the methyltransferase superfamily
JHS79_09125	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JHS79_09135	COG0167	dihydroorotate dehydrogenase activity
JHS79_09150	COG0308	aminopeptidase N
JHS79_09165	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
JHS79_09170	COG1956	GAF domain-containing protein
JHS79_09175	COG1132	(ABC) transporter
JHS79_09180	COG2995	paraquat-inducible protein a
JHS79_09185	COG3008	intermembrane lipid transfer
JHS79_09190	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JHS79_09190	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JHS79_09210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JHS79_09215	COG1666	GTP binding
JHS79_09225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHS79_09230	COG4597	amino acid ABC transporter
JHS79_09235	COG0765	amino acid transport
JHS79_09240	COG1126	abc transporter atp-binding protein
JHS79_09245	COG0670	Belongs to the BI1 family
JHS79_09255	COG2920	part of a sulfur-relay system
JHS79_09260	COG1254	Belongs to the acylphosphatase family
JHS79_09265	COG0840	transmembrane signaling receptor activity
JHS79_09270	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JHS79_09310	COG3706	GGDEF domain
JHS79_09315	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JHS79_09320	COG0602	queuosine metabolic process
JHS79_09325	COG0561	phosphatase activity
JHS79_09350	COG2828	Protein conserved in bacteria
JHS79_09360	COG0372	Belongs to the citrate synthase family
JHS79_09365	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
JHS79_09395	COG0730	response to heat
JHS79_09415	COG0457	Tetratricopeptide repeat
JHS79_09485	COG4790	Type iii secretion
JHS79_09490	COG4794	Type iii secretion
JHS79_09495	COG4791	protein targeting
JHS79_09500	COG4792	protein secretion
JHS79_09510	COG1073	alpha beta
JHS79_09515	COG1073	alpha beta
JHS79_09545	COG3177	Filamentation induced by cAMP protein fic
JHS79_09565	COG4669	(LipO)protein
JHS79_09635	COG1012	belongs to the aldehyde dehydrogenase family
JHS79_09640	COG3284	Transcriptional regulator
JHS79_09670	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
JHS79_09675	COG0363	glucosamine-6-phosphate deaminase activity
JHS79_09680	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
JHS79_09685	COG4565	transcriptional regulatory protein
JHS79_09690	COG3290	protein histidine kinase activity
JHS79_09705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHS79_09720	COG1858	cytochrome C peroxidase
JHS79_09740	COG0527	aspartate kinase activity
JHS79_09745	COG0662	Cupin 2, conserved barrel domain protein
JHS79_09750	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHS79_09755	COG0456	acetyltransferase
JHS79_09760	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHS79_09780	COG4176	ABC-type proline glycine betaine transport system permease component
JHS79_09785	COG2113	Glycine betaine
JHS79_09805	COG1028	Short-chain dehydrogenase reductase Sdr
JHS79_09815	COG0745	RESPONSE REGULATOR receiver
JHS79_09820	COG0642	Histidine kinase
JHS79_09825	COG1368	sulfuric ester hydrolase activity
JHS79_09850	COG1115	amino acid carrier protein
JHS79_09860	COG1280	lysine exporter protein (LysE YggA)
JHS79_09865	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JHS79_09870	COG1560	Kdo2-lipid A biosynthetic process
JHS79_09875	COG0531	amino acid
JHS79_09885	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
JHS79_09890	COG3063	Type IV pilus biogenesis stability protein PilW
JHS79_09905	COG5002	protein histidine kinase activity
JHS79_09905	COG0784	Response regulator, receiver
JHS79_09905	COG2205	protein histidine kinase activity
JHS79_09920	COG0110	maltose O-acetyltransferase activity
JHS79_09940	COG2315	Protein conserved in bacteria
JHS79_09945	COG1846	Transcriptional regulator
JHS79_09960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JHS79_09970	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JHS79_09975	COG1227	inorganic diphosphatase activity
JHS79_09980	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHS79_09985	COG1012	belongs to the aldehyde dehydrogenase family
JHS79_09990	COG2957	Belongs to the agmatine deiminase family
JHS79_10000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JHS79_10005	COG1012	belongs to the aldehyde dehydrogenase family
JHS79_10010	COG1396	sequence-specific DNA binding
JHS79_10010	COG1917	Cupin 2, conserved barrel domain protein
JHS79_10015	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
JHS79_10020	COG0174	glutamine synthetase
JHS79_10025	COG1757	Na H antiporter
JHS79_10045	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHS79_10050	COG1280	lysine exporter protein (LysE YggA)
JHS79_10235	COG1783	phage Terminase large subunit
JHS79_10285	COG0557	exoribonuclease II activity
JHS79_10290	COG1278	Cold shock
JHS79_10395	COG0625	glutathione transferase activity
JHS79_10405	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
JHS79_10415	COG2195	Cleaves the N-terminal amino acid of tripeptides
JHS79_10425	COG0601	transmembrane transport
JHS79_10430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHS79_10435	COG0444	Belongs to the ABC transporter superfamily
JHS79_10450	COG3291	Pkd domain containing protein
JHS79_10460	COG1177	transmembrane transport
JHS79_10465	COG1176	ABC-type spermidine putrescine transport system, permease component I
JHS79_10470	COG3842	ATPase activity
JHS79_10475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JHS79_10495	COG3938	Belongs to the proline racemase family
JHS79_10525	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
JHS79_10530	COG1451	nucleotide metabolic process
JHS79_10545	COG1489	DNA binding
JHS79_10675	COG0583	DNA-binding transcription factor activity
JHS79_10695	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
JHS79_10700	COG4139	cobalamin transport
JHS79_10705	COG2988	succinylglutamate desuccinylase activity
JHS79_10725	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JHS79_10735	COG0702	epimerase
JHS79_10740	COG1823	symporter activity
JHS79_10745	COG2925	Exonuclease
JHS79_10750	COG1380	Effector of murein hydrolase LrgA
JHS79_10755	COG1346	cytolysis
JHS79_10760	COG0295	cytidine deaminase activity
JHS79_10765	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
JHS79_10770	COG0500	methyltransferase
JHS79_10780	COG0776	regulation of translation
JHS79_10790	COG0072	phenylalanine-tRNA ligase activity
JHS79_10790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHS79_10795	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
JHS79_10800	COG3706	GGDEF domain
JHS79_10830	COG0393	Putative heavy-metal-binding
JHS79_10840	COG0291	Belongs to the bacterial ribosomal protein bL35 family
JHS79_10850	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JHS79_10865	COG2188	Transcriptional regulator
JHS79_10870	COG1228	amidohydrolase
JHS79_10875	COG0010	Belongs to the arginase family
JHS79_10880	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
JHS79_10885	COG2986	histidine ammonia-lyase
JHS79_10900	COG0247	lactate metabolic process
JHS79_10900	COG0277	FAD linked oxidase domain protein
JHS79_10935	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JHS79_10950	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
JHS79_10955	COG1643	Atp-dependent helicase
JHS79_10960	COG0281	malic enzyme
JHS79_10965	COG2949	membrane
JHS79_10970	COG0471	metal ion transport
JHS79_10995	COG0492	ferredoxin-NADP+ reductase activity
JHS79_11000	COG4988	ABC transporter
JHS79_11005	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
JHS79_11010	COG3048	D-serine ammonia-lyase activity
JHS79_11015	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
JHS79_11025	COG4191	Histidine kinase
JHS79_11025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHS79_11040	COG3070	regulator of competence-specific genes
JHS79_11050	COG2431	L-lysine efflux transmembrane transporter activity
JHS79_11060	COG0076	glutamate decarboxylase activity
JHS79_11065	COG1737	Transcriptional regulator
JHS79_11075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JHS79_11080	COG3273	potassium ion transport
JHS79_11080	COG2985	domain, Protein
JHS79_11085	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JHS79_11100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JHS79_11115	COG4181	ATPase activity
JHS79_11120	COG0534	Mate efflux family protein
JHS79_11125	COG0702	epimerase
JHS79_11130	COG3005	denitrification pathway
JHS79_11160	COG2814	Major facilitator Superfamily
JHS79_11165	COG1187	pseudouridine synthase activity
JHS79_11170	COG1061	Type III restriction enzyme res subunit
JHS79_11190	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JHS79_11215	COG3313	Fe-S protein
JHS79_11240	COG0493	'glutamate synthase
JHS79_11250	COG0398	Pfam SNARE associated Golgi protein
JHS79_11255	COG4134	Bacterial extracellular solute-binding protein
JHS79_11260	COG4135	transport system, permease component
JHS79_11265	COG4136	ATPase activity
JHS79_11270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JHS79_11280	COG3604	Transcriptional regulator
JHS79_11285	COG1151	hydroxylamine reductase activity
JHS79_11290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JHS79_11300	COG0564	pseudouridine synthase activity
JHS79_11310	COG0733	neurotransmitter:sodium symporter activity
JHS79_11320	COG0626	cystathionine gamma-synthase activity
JHS79_11325	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
JHS79_11330	COG5380	lipid catabolic process
JHS79_11335	COG0519	Catalyzes the synthesis of GMP from XMP
JHS79_11350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHS79_11355	COG1983	PspC domain protein
JHS79_11365	COG1842	Phage shock protein A
JHS79_11370	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
JHS79_11385	COG4171	peptide transport system, permease
JHS79_11395	COG4172	Belongs to the ABC transporter superfamily
JHS79_11405	COG1227	inorganic diphosphatase activity
JHS79_11420	COG0243	molybdopterin cofactor binding
JHS79_11425	COG3005	denitrification pathway
JHS79_11430	COG4459	periplasmic nitrate reductase
JHS79_11435	COG0390	transport system, permease component
JHS79_11445	COG2116	formate transmembrane transporter activity
JHS79_11470	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JHS79_11485	COG2207	Transcriptional regulator
JHS79_11485	COG1917	Cupin 2, conserved barrel domain protein
JHS79_11490	COG1335	isochorismatase
JHS79_11495	COG0577	efflux transmembrane transporter activity
JHS79_11495	COG1136	(ABC) transporter
JHS79_11500	COG0577	efflux transmembrane transporter activity
JHS79_11500	COG1136	(ABC) transporter
JHS79_11505	COG0577	efflux transmembrane transporter activity
JHS79_11505	COG1136	(ABC) transporter
JHS79_11515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHS79_11545	COG3118	belongs to the thioredoxin family
JHS79_11550	COG4232	protein-disulfide reductase activity
JHS79_11590	COG2863	cytochrome
JHS79_11595	COG3258	Cytochrome c
JHS79_11600	COG2995	paraquat-inducible protein a
JHS79_11605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JHS79_11605	COG3008	intermembrane lipid transfer
JHS79_11615	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
JHS79_11640	COG4166	transmembrane transport
JHS79_11645	COG0284	orotidine-5'-phosphate decarboxylase activity
JHS79_11650	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
JHS79_11655	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
JHS79_11665	COG0539	negative regulation of cytoplasmic translation
JHS79_11670	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JHS79_11675	COG0616	signal peptide processing
JHS79_11680	COG1028	Short-chain dehydrogenase reductase Sdr
JHS79_11695	COG0587	DNA-directed DNA polymerase activity
JHS79_11700	COG0784	Response regulator, receiver
JHS79_11700	COG0835	chemotaxis
JHS79_11705	COG1940	carbohydrate kinase activity
JHS79_11710	COG0469	pyruvate kinase activity
JHS79_11715	COG4667	esterase of the alpha-beta hydrolase superfamily
JHS79_11730	COG0733	neurotransmitter:sodium symporter activity
JHS79_11745	COG1263	PTS System
JHS79_11745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHS79_11750	COG0084	hydrolase, TatD family'
JHS79_11760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JHS79_11765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JHS79_11795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JHS79_11800	COG0416	fatty acid biosynthetic process
JHS79_11810	COG1399	metal-binding, possibly nucleic acid-binding protein
JHS79_11815	COG0424	maF-like protein
JHS79_11820	COG0564	pseudouridine synthase activity
JHS79_11825	COG1530	ribonuclease E activity
JHS79_11830	COG0659	secondary active sulfate transmembrane transporter activity
JHS79_11835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JHS79_11840	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JHS79_11850	COG0572	uridine kinase
JHS79_11855	COG0489	protein tyrosine kinase activity
JHS79_11860	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHS79_11860	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JHS79_11870	COG2186	Transcriptional regulator
JHS79_11875	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JHS79_11880	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JHS79_11885	COG3318	Belongs to the UPF0149 family
JHS79_11885	COG3012	SEC-C Motif Domain Protein
JHS79_11890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHS79_11895	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
JHS79_11900	COG2885	chlorophyll binding
JHS79_11905	COG0823	Involved in the tonB-independent uptake of proteins
JHS79_11920	COG0811	peptide transport
JHS79_11925	COG0824	Thioesterase
JHS79_11935	COG4890	Cyd operon protein YbgT
JHS79_11940	COG1294	oxidase, subunit
JHS79_11945	COG1271	oxidase subunit
JHS79_11950	COG2255	four-way junction helicase activity
JHS79_11955	COG0632	four-way junction helicase activity
JHS79_11960	COG0840	transmembrane signaling receptor activity
JHS79_11965	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JHS79_11970	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
JHS79_11975	COG1801	Protein of unknown function DUF72
JHS79_11980	COG4106	trans-aconitate 2-methyltransferase activity
JHS79_11985	COG0500	methyltransferase
JHS79_11990	COG4067	protein conserved in archaea
JHS79_11990	COG0189	ligase activity
JHS79_12010	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JHS79_12015	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
JHS79_12020	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
JHS79_12025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JHS79_12030	COG1434	Gram-negative-bacterium-type cell wall biogenesis
JHS79_12035	COG0745	RESPONSE REGULATOR receiver
JHS79_12040	COG3381	protein complex oligomerization
JHS79_12045	COG1609	Transcriptional regulator
JHS79_12050	COG3070	regulator of competence-specific genes
JHS79_12070	COG0297	glycogen (starch) synthase activity
JHS79_12075	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JHS79_12080	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHS79_12090	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JHS79_12100	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JHS79_12105	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
JHS79_12110	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JHS79_12120	COG0542	response to heat
JHS79_12125	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JHS79_12130	COG1278	Cold shock
JHS79_12140	COG1187	pseudouridine synthase activity
JHS79_12145	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JHS79_12155	COG1199	ATP-dependent helicase activity
JHS79_12160	COG0730	response to heat
JHS79_12165	COG3923	Primosomal replication protein n
JHS79_12175	COG0708	Exodeoxyribonuclease III
JHS79_12190	COG4657	Part of a membrane complex involved in electron transport
JHS79_12195	COG2878	Part of a membrane complex involved in electron transport
JHS79_12200	COG4656	Part of a membrane complex involved in electron transport
JHS79_12205	COG4658	electron transport chain
JHS79_12210	COG4659	FMN binding
JHS79_12215	COG4660	Part of a membrane complex involved in electron transport
JHS79_12220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JHS79_12225	COG0346	lactoylglutathione lyase activity
JHS79_12235	COG2885	chlorophyll binding
JHS79_12240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JHS79_12245	COG2056	Na+-H+ antiporter family
JHS79_12255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JHS79_12275	COG1454	alcohol dehydrogenase
JHS79_12275	COG1012	belongs to the aldehyde dehydrogenase family
JHS79_12280	COG2095	MarC family integral membrane protein
JHS79_12285	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHS79_12290	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JHS79_12295	COG1757	Na H antiporter
JHS79_12310	COG3081	Nucleoid-associated protein
JHS79_12315	COG3082	Protein of unknown function (DUF1414)
JHS79_12320	COG3083	sulfuric ester hydrolase activity
JHS79_12330	COG0123	including yeast histone deacetylase and acetoin utilization protein
JHS79_12345	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHS79_12350	COG0778	Nitroreductase
JHS79_12355	COG0446	pyridine nucleotide-disulphide oxidoreductase
JHS79_12355	COG1902	pentaerythritol trinitrate reductase activity
JHS79_12360	COG0616	signal peptide processing
JHS79_12365	COG0252	asparaginase activity
JHS79_12370	COG3139	Protein of unknown function (DUF1315)
JHS79_12380	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHS79_12385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JHS79_12400	COG2226	methyltransferase
JHS79_12415	COG1785	Belongs to the alkaline phosphatase family
JHS79_12425	COG0346	lactoylglutathione lyase activity
JHS79_12430	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JHS79_12435	COG0668	transmembrane transport
JHS79_12440	COG2983	Belongs to the UPF0260 family
JHS79_12445	COG2261	transglycosylase associated protein
JHS79_12460	COG3681	Belongs to the UPF0597 family
JHS79_12465	COG0251	oxidation-reduction process
JHS79_12470	COG0814	amino acid
JHS79_12475	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
JHS79_12480	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JHS79_12485	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JHS79_12495	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
JHS79_12500	COG2832	Protein of unknown function (DUF454)
JHS79_12505	COG0745	RESPONSE REGULATOR receiver
JHS79_12510	COG0583	DNA-binding transcription factor activity
JHS79_12515	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JHS79_12520	COG1286	toxin biosynthetic process
JHS79_12525	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
JHS79_12530	COG0285	dihydrofolate synthase activity
JHS79_12535	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JHS79_12540	COG0101	tRNA pseudouridine synthase activity
JHS79_12550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JHS79_12555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JHS79_12560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JHS79_12565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JHS79_12565	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JHS79_12570	COG0431	NADPH-dependent FMN reductase
JHS79_12580	COG3101	peptidyl-lysine hydroxylation
JHS79_12585	COG2860	membrane
JHS79_12590	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JHS79_12595	COG2890	protein-(glutamine-N5) methyltransferase activity
JHS79_12600	COG2840	Smr protein MutS2
JHS79_12605	COG2062	phosphohistidine phosphatase, SixA
JHS79_12620	COG1024	Enoyl-CoA hydratase
JHS79_12620	COG1250	3-hydroxyacyl-CoA dehydrogenase
JHS79_12625	COG0183	Belongs to the thiolase family
JHS79_12640	COG2067	long-chain fatty acid transport protein
JHS79_12645	COG2067	long-chain fatty acid transport protein
JHS79_12650	COG2853	Lipoprotein
JHS79_12665	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JHS79_12670	COG1138	Cytochrome C-type biogenesis protein
JHS79_12675	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JHS79_12680	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JHS79_12685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JHS79_12690	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JHS79_12695	COG4133	protoheme IX ABC transporter activity
JHS79_12705	COG0835	chemotaxis
JHS79_12715	COG1192	Involved in chromosome partitioning
JHS79_12720	COG2201	protein-glutamate methylesterase activity
JHS79_12725	COG2198	Histidine kinase
JHS79_12725	COG0784	Response regulator, receiver
JHS79_12725	COG0643	Histidine kinase
JHS79_12730	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
JHS79_12770	COG1987	bacterial-type flagellum assembly
JHS79_12820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
JHS79_12830	COG1677	Flagellar hook-basal body complex protein FliE
JHS79_12850	COG1516	flagellar protein fliS
JHS79_12860	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JHS79_12865	COG1334	flagellar protein FlaG
JHS79_12870	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHS79_12875	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHS79_12880	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHS79_12885	COG2837	iron assimilation
JHS79_12910	COG1393	Belongs to the ArsC family
JHS79_12915	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JHS79_12930	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
JHS79_12935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JHS79_12940	COG2716	regulation of RNA biosynthetic process
JHS79_12945	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JHS79_12960	COG4783	chaperone-mediated protein folding
JHS79_12965	COG1393	Belongs to the ArsC family
JHS79_12985	COG2233	PERMEase
JHS79_12990	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JHS79_12995	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JHS79_13000	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JHS79_13010	COG0045	succinate-CoA ligase (ADP-forming) activity
JHS79_13015	COG0508	dehydrogenase complex catalyzes the overall conversion of
JHS79_13020	COG0567	Dehydrogenase, E1 component
JHS79_13025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JHS79_13030	COG1053	succinate dehydrogenase
JHS79_13035	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JHS79_13050	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JHS79_13060	COG0033	Phosphoglucomutase
JHS79_13065	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
JHS79_13070	COG0596	Alpha beta hydrolase
JHS79_13090	COG0735	belongs to the Fur family
JHS79_13095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHS79_13100	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHS79_13100	COG1263	PTS System
JHS79_13105	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
JHS79_13110	COG1940	carbohydrate kinase activity
JHS79_13110	COG1846	Transcriptional regulator
JHS79_13115	COG4651	solute:proton antiporter activity
JHS79_13115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JHS79_13120	COG0367	asparagine synthase
JHS79_13125	COG0250	Participates in transcription elongation, termination and antitermination
JHS79_13130	COG3104	oligopeptide transport
JHS79_13135	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JHS79_13140	COG0563	adenylate kinase activity
JHS79_13145	COG0326	Molecular chaperone. Has ATPase activity
JHS79_13150	COG3710	Transcriptional regulator
JHS79_13170	COG0622	Phosphoesterase
JHS79_13195	COG1090	epimerase
JHS79_13200	COG0300	oxidoreductase activity
JHS79_13205	COG3118	belongs to the thioredoxin family
JHS79_13210	COG0457	Tetratricopeptide repeat
JHS79_13210	COG3118	belongs to the thioredoxin family
JHS79_13215	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
JHS79_13220	COG1215	transferase activity, transferring glycosyl groups
JHS79_13225	COG1215	transferase activity, transferring glycosyl groups
JHS79_13250	COG2194	sulfuric ester hydrolase activity
JHS79_13255	COG0330	HflC and HflK could
JHS79_13275	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JHS79_13280	COG3115	cell septum assembly
JHS79_13285	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
JHS79_13290	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JHS79_13295	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHS79_13300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JHS79_13305	COG2190	(PTS) system
JHS79_13310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHS79_13315	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHS79_13320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHS79_13325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHS79_13335	COG3951	Flagellar rod assembly protein muramidase FlgJ
JHS79_13335	COG1705	Flagellar rod assembly protein muramidase FlgJ
JHS79_13340	COG1706	bacterial-type flagellum-dependent cell motility
JHS79_13345	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JHS79_13355	COG4787	bacterial-type flagellum-dependent cell motility
JHS79_13370	COG1558	bacterial-type flagellum-dependent cell motility
JHS79_13375	COG1815	bacterial-type flagellum-dependent cell motility
JHS79_13380	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
JHS79_13385	COG0784	Response regulator, receiver
JHS79_13385	COG0835	chemotaxis
JHS79_13435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHS79_13440	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JHS79_13450	COG2217	Heavy metal translocating P-type atpase
JHS79_13450	COG2608	mercury ion transmembrane transporter activity
JHS79_13485	COG2840	Smr protein MutS2
JHS79_13490	COG1187	pseudouridine synthase activity
JHS79_13500	COG0737	Belongs to the 5'-nucleotidase family
JHS79_13505	COG2877	3-deoxy-8-phosphooctulonate synthase activity
JHS79_13510	COG2912	Transglutaminase-like superfamily
JHS79_13515	COG3094	Invasion gene expression up-regulator, SirB
JHS79_13520	COG2890	protein-(glutamine-N5) methyltransferase activity
JHS79_13525	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JHS79_13530	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JHS79_13535	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JHS79_13540	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JHS79_13545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JHS79_13550	COG0193	aminoacyl-tRNA hydrolase activity
JHS79_13555	COG0012	GTP binding
JHS79_13670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JHS79_13675	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JHS79_13680	COG1702	phosphate starvation-inducible protein PhoH
JHS79_13685	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JHS79_13690	COG4535	Mg2 and Co2 transporter CorC
JHS79_13695	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JHS79_13700	COG2888	peptidyl-tyrosine sulfation
JHS79_13705	COG0495	leucyl-tRNA aminoacylation
JHS79_13710	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
JHS79_13715	COG1466	dna polymerase III delta subunit
JHS79_13720	COG0799	negative regulation of ribosome biogenesis
JHS79_13725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JHS79_13730	COG0768	penicillin binding
JHS79_13735	COG0772	Belongs to the SEDS family
JHS79_13740	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JHS79_13745	COG1686	Belongs to the peptidase S11 family
JHS79_13750	COG2921	Belongs to the UPF0250 family
JHS79_13755	COG0321	lipoyl(octanoyl) transferase activity
JHS79_13760	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JHS79_13765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JHS79_13770	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHS79_13785	COG0366	Alpha amylase catalytic
JHS79_13790	COG1263	PTS System
JHS79_13790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHS79_13800	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
JHS79_13805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JHS79_13810	COG2011	ABC-type metal ion transport system permease component
JHS79_13815	COG1464	Belongs to the NlpA lipoprotein family
JHS79_13820	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
JHS79_13830	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JHS79_13830	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
JHS79_13845	COG1611	Belongs to the LOG family
JHS79_13850	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JHS79_13860	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
JHS79_13865	COG2363	Small membrane protein
JHS79_13875	COG0583	DNA-binding transcription factor activity
JHS79_13880	COG0301	tRNA thio-modification
JHS79_13880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHS79_13885	COG2885	chlorophyll binding
JHS79_13890	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JHS79_13895	COG1722	exodeoxyribonuclease VII activity
JHS79_13900	COG0142	geranyltranstransferase activity
JHS79_13905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JHS79_13910	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JHS79_13915	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JHS79_13920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JHS79_13940	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHS79_13940	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHS79_13945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JHS79_13950	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JHS79_13955	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JHS79_13965	COG1073	alpha beta
JHS79_13970	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
JHS79_13975	COG2252	PERMEase
JHS79_13980	COG2195	Cleaves the N-terminal amino acid of tripeptides
JHS79_14005	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JHS79_14005	COG0047	phosphoribosylformylglycinamidine synthase activity
JHS79_14010	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
JHS79_14015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JHS79_14020	COG0739	heme binding
JHS79_14025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHS79_14035	COG0316	Belongs to the HesB IscA family
JHS79_14040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JHS79_14045	COG0628	permease
JHS79_14050	COG2813	Specifically methylates the guanine in position
JHS79_14055	COG2205	protein histidine kinase activity
JHS79_14055	COG0784	Response regulator, receiver
JHS79_14055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHS79_14055	COG2198	Histidine kinase
JHS79_14060	COG0747	negative chemotaxis
JHS79_14070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JHS79_14075	COG0444	Belongs to the ABC transporter superfamily
JHS79_14080	COG4608	Belongs to the ABC transporter superfamily
JHS79_14090	COG2971	BadF BadG BcrA BcrD
JHS79_14105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHS79_14110	COG3842	ATPase activity
JHS79_14120	COG1840	ABC-type Fe3 transport system, periplasmic component
JHS79_14125	COG0004	ammonium transporteR
JHS79_14135	COG3112	Uncharacterised protein family (UPF0231)
JHS79_14140	COG1049	propionate catabolic process, 2-methylcitrate cycle
JHS79_14145	COG1752	Esterase of the alpha-beta hydrolase superfamily
JHS79_14150	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JHS79_14155	COG1643	Atp-dependent helicase
JHS79_14160	COG1489	DNA binding
JHS79_14170	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JHS79_14180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JHS79_14185	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JHS79_14190	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JHS79_14195	COG1560	Kdo2-lipid A biosynthetic process
JHS79_14200	COG0842	Transport permease protein
JHS79_14205	COG1131	(ABC) transporter
JHS79_14210	COG0659	secondary active sulfate transmembrane transporter activity
JHS79_14215	COG0288	reversible hydration of carbon dioxide
JHS79_14230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JHS79_14235	COG0508	dehydrogenase complex catalyzes the overall conversion of
JHS79_14240	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
JHS79_14245	COG2186	Transcriptional regulator
JHS79_14255	COG0157	Belongs to the NadC ModD family
JHS79_14265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHS79_14270	COG1459	type II secretion system
JHS79_14280	COG0237	dephospho-CoA kinase activity
JHS79_14285	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
JHS79_14290	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JHS79_14295	COG0335	large ribosomal subunit rRNA binding
JHS79_14300	COG0336	Belongs to the RNA methyltransferase TrmD family
JHS79_14305	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JHS79_14310	COG0228	four-way junction DNA binding
JHS79_14315	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JHS79_14320	COG4137	Cytochrome C assembly protein
JHS79_14325	COG4536	flavin adenine dinucleotide binding
JHS79_14330	COG1854	S-ribosylhomocysteine lyase activity
JHS79_14340	COG2918	glutathione biosynthetic process
JHS79_14345	COG0612	Peptidase, M16
JHS79_14350	COG1238	metal cluster binding
JHS79_14360	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
JHS79_14365	COG5016	pyruvate
JHS79_14365	COG0511	ligase activity, forming carbon-carbon bonds
JHS79_14370	COG3630	sodium ion export across plasma membrane
JHS79_14430	COG0527	aspartate kinase activity
JHS79_14435	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JHS79_14440	COG2137	regulation of response to DNA damage stimulus
JHS79_14445	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JHS79_14450	COG1546	Belongs to the CinA family
JHS79_14455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JHS79_14460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JHS79_14470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JHS79_14475	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JHS79_14480	COG0585	pseudouridine synthase activity
JHS79_14485	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JHS79_14490	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JHS79_14495	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JHS79_14500	COG0148	phosphopyruvate hydratase activity
JHS79_14505	COG0504	CTP synthase activity
JHS79_14510	COG3956	TIGRFAM MazG family protein
JHS79_14515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JHS79_14520	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JHS79_14530	COG0736	holo-[acyl-carrier-protein] synthase activity
JHS79_14535	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JHS79_14540	COG1381	Involved in DNA repair and RecF pathway recombination
JHS79_14545	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JHS79_14550	COG0571	ribonuclease III activity
JHS79_14560	COG0481	GTPase activity
JHS79_14565	COG3086	response to oxidative stress
JHS79_14575	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
JHS79_14580	COG1595	DNA-templated transcription, initiation
JHS79_14585	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JHS79_14590	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JHS79_14595	COG0354	folic acid binding
JHS79_14610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JHS79_14615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JHS79_14620	COG3079	Belongs to the UPF0149 family
JHS79_14625	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
JHS79_14635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JHS79_14640	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JHS79_14645	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JHS79_14655	COG0583	DNA-binding transcription factor activity
JHS79_14665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JHS79_14670	COG0668	transmembrane transport
JHS79_14675	COG0191	fructose-bisphosphate aldolase activity
JHS79_14680	COG0126	phosphoglycerate kinase activity
JHS79_14685	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JHS79_14690	COG4771	TonB-dependent receptor
JHS79_14695	COG0583	DNA-binding transcription factor activity
JHS79_14700	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JHS79_14705	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JHS79_14715	COG3091	SprT-like family
JHS79_14720	COG2356	endonuclease I
JHS79_14725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JHS79_14730	COG0189	ligase activity
JHS79_14735	COG1678	Uncharacterized ACR, COG1678
JHS79_14740	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JHS79_14755	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JHS79_14760	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JHS79_14765	COG0762	integral membrane protein
JHS79_14770	COG1872	DUF167
JHS79_14780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JHS79_14785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JHS79_14790	COG2066	Belongs to the glutaminase family
JHS79_14800	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JHS79_14810	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
JHS79_14815	COG0741	lytic transglycosylase activity
JHS79_14885	COG1012	belongs to the aldehyde dehydrogenase family
JHS79_14930	COG3437	response regulator, receiver
JHS79_14940	COG3394	polysaccharide catabolic process
JHS79_14945	COG1486	melibiose metabolic process
JHS79_14950	COG1447	Phosphotransferase system cellobiose-specific component IIA
JHS79_14955	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JHS79_14960	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
JHS79_14965	COG0726	polysaccharide deacetylase
JHS79_15005	COG1028	Short-chain dehydrogenase reductase Sdr
JHS79_15020	COG0795	lipopolysaccharide-transporting ATPase activity
JHS79_15025	COG0795	lipopolysaccharide-transporting ATPase activity
JHS79_15030	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JHS79_15035	COG2927	DNA polymerase III (CHI subunit)
JHS79_15040	COG0525	valine-tRNA ligase activity
JHS79_15065	COG2235	arginine
JHS79_15070	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JHS79_15080	COG0540	Belongs to the ATCase OTCase family
JHS79_15085	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
JHS79_15090	COG0251	oxidation-reduction process
JHS79_15095	COG0204	Acyl-transferase
JHS79_15100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JHS79_15105	COG5007	Belongs to the BolA IbaG family
JHS79_15115	COG2854	intermembrane phospholipid transfer
JHS79_15120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JHS79_15125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JHS79_15130	COG1127	ABC transporter
JHS79_15140	COG0517	IMP dehydrogenase activity
JHS79_15140	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JHS79_15150	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JHS79_15155	COG1137	ATPase activity
JHS79_15165	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JHS79_15170	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHS79_15175	COG1660	Displays ATPase and GTPase activities
JHS79_15180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHS79_15185	COG2239	Acts as a magnesium transporter
JHS79_15190	COG0312	modulator of DNA gyrase
JHS79_15195	COG3028	Belongs to the UPF0307 family
JHS79_15200	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHS79_15205	COG0564	pseudouridine synthase activity
JHS79_15215	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JHS79_15220	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
JHS79_15225	COG0312	modulator of DNA gyrase
JHS79_15230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JHS79_15235	COG3164	Protein of unknown function
JHS79_15245	COG0424	maF-like protein
JHS79_15250	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JHS79_15255	COG1792	Involved in formation and maintenance of cell shape
JHS79_15260	COG1077	Cell shape determining protein MreB Mrl
JHS79_15295	COG2165	general secretion pathway protein
JHS79_15305	COG1459	type II secretion system
JHS79_15310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHS79_15320	COG3267	Type II secretory pathway component ExeA
JHS79_15320	COG3409	Peptidoglycan-binding domain 1 protein
JHS79_15345	COG2199	diguanylate cyclase activity
JHS79_15345	COG2200	EAL domain
JHS79_15350	COG0629	single-stranded DNA binding
JHS79_15365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JHS79_15375	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JHS79_15380	COG0527	aspartate kinase activity
JHS79_15385	COG1410	methionine synthase
JHS79_15385	COG0646	methionine synthase
JHS79_15405	COG3335	DDE superfamily endonuclease
JHS79_15460	COG0175	sulfate reduction
JHS79_15465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JHS79_15470	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JHS79_15490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHS79_15495	COG0735	belongs to the Fur family
JHS79_15505	COG0166	Belongs to the GPI family
JHS79_15510	COG0432	Pfam Uncharacterised protein family UPF0047
JHS79_15520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHS79_15535	COG0359	binds to the 23S rRNA
JHS79_15545	COG2965	DNA replication, synthesis of RNA primer
JHS79_15550	COG0360	Binds together with S18 to 16S ribosomal RNA
JHS79_15555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JHS79_15560	COG0338	D12 class N6 adenine-specific DNA methyltransferase
JHS79_15570	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JHS79_15575	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JHS79_15605	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
JHS79_15615	COG0678	peroxiredoxin activity
JHS79_15615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JHS79_15625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
JHS79_15625	COG0165	Argininosuccinate lyase
JHS79_15630	COG0137	argininosuccinate synthase activity
JHS79_15635	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JHS79_15640	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JHS79_15645	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JHS79_15650	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JHS79_15660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JHS79_15665	COG0460	homoserine dehydrogenase
JHS79_15665	COG0527	aspartate kinase activity
JHS79_15670	COG0626	cystathionine gamma-synthase activity
JHS79_15680	COG0281	malic enzyme
JHS79_15690	COG2906	2 iron, 2 sulfur cluster binding
JHS79_15695	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JHS79_15700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JHS79_15705	COG0049	tRNA binding
JHS79_15720	COG2923	Belongs to the DsrF TusC family
JHS79_15725	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JHS79_15730	COG2964	Protein conserved in bacteria
JHS79_15735	COG0545	Peptidyl-prolyl cis-trans isomerase
JHS79_15745	COG2900	Belongs to the SlyX family
JHS79_15750	COG1446	asparaginase
JHS79_15755	COG1047	Peptidyl-prolyl cis-trans
JHS79_15770	COG2249	NAD(P)H dehydrogenase (quinone) activity
JHS79_15775	COG0488	(ABC) transporter
JHS79_15785	COG0429	hydrolase of the alpha beta-hydrolase fold
JHS79_15790	COG3089	Belongs to the UPF0270 family
JHS79_15795	COG3954	Phosphoribulokinase
JHS79_15800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JHS79_15810	COG1012	belongs to the aldehyde dehydrogenase family
JHS79_15820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JHS79_15825	COG0512	Glutamine amidotransferase of anthranilate synthase
JHS79_15840	COG0180	Tryptophanyl-tRNA synthetase
JHS79_15845	COG0546	phosphoglycolate phosphatase activity
JHS79_15850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JHS79_15855	COG0557	exoribonuclease II activity
JHS79_15860	COG1959	2 iron, 2 sulfur cluster binding
JHS79_15865	COG1017	nitric oxide dioxygenase activity
JHS79_15865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JHS79_15870	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
JHS79_15875	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JHS79_15880	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
JHS79_15885	COG0330	HflC and HflK could
JHS79_15890	COG0330	HflC and HflK could
JHS79_15895	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JHS79_15905	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JHS79_15910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JHS79_15915	COG0860	N-Acetylmuramoyl-L-alanine amidase
JHS79_15920	COG0802	atpase or kinase
JHS79_15925	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JHS79_15995	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JHS79_16000	COG1162	GTPase activity
JHS79_16005	COG0688	phosphatidylethanolamine metabolic process
JHS79_16010	COG0471	metal ion transport
JHS79_16025	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JHS79_16030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHS79_16035	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
JHS79_16040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JHS79_16045	COG1045	serine acetyltransferase
JHS79_16050	COG4942	peptidase
JHS79_16070	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JHS79_16075	COG1053	succinate dehydrogenase
JHS79_16080	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JHS79_16085	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JHS79_16090	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
JHS79_16100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JHS79_16105	COG1509	lysine 2,3-aminomutase activity
JHS79_16110	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHS79_16125	COG0459	protein refolding
JHS79_16135	COG0534	Mate efflux family protein
JHS79_16140	COG0205	6-phosphofructokinase activity
JHS79_16150	COG3678	ATP-independent chaperone mediated protein folding
JHS79_16155	COG0745	RESPONSE REGULATOR receiver
JHS79_16160	COG2205	protein histidine kinase activity
JHS79_16170	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JHS79_16175	COG3030	protein affecting phage T7 exclusion by the F plasmid
JHS79_16180	COG1027	Aspartate ammonia-lyase
JHS79_16185	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JHS79_16190	COG4232	protein-disulfide reductase activity
JHS79_16200	COG3263	regulation of cellular component size
JHS79_16210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHS79_16230	COG0784	Response regulator, receiver
JHS79_16230	COG2198	Histidine kinase
JHS79_16230	COG2205	protein histidine kinase activity
JHS79_16235	COG2814	Major facilitator Superfamily
JHS79_16250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JHS79_16255	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JHS79_16260	COG0511	ligase activity, forming carbon-carbon bonds
JHS79_16265	COG0439	Biotin carboxylase
JHS79_16270	COG2264	protein methyltransferase activity
JHS79_16275	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JHS79_16280	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JHS79_16285	COG2814	Major facilitator Superfamily
JHS79_16290	COG0488	(ABC) transporter
JHS79_16295	COG3706	GGDEF domain
JHS79_16390	COG1982	Orn Lys Arg decarboxylase major
JHS79_16395	COG0531	amino acid
JHS79_16400	COG3710	Transcriptional regulator
JHS79_16405	COG0789	Transcriptional regulator
JHS79_16410	COG0138	bifunctional purine biosynthesis protein purh
JHS79_16415	COG0151	Belongs to the GarS family
JHS79_16430	COG1253	flavin adenine dinucleotide binding
JHS79_16445	COG1573	uracil-dna glycosylase
JHS79_16450	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JHS79_16465	COG2816	NAD+ diphosphatase activity
JHS79_16470	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
JHS79_16475	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JHS79_16480	COG0085	RNA polymerase activity
JHS79_16485	COG0222	ribosome binding
JHS79_16490	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JHS79_16495	COG0081	regulation of translation
JHS79_16500	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
JHS79_16505	COG0250	Participates in transcription elongation, termination and antitermination
JHS79_16510	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JHS79_16515	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JHS79_16550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JHS79_16560	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHS79_16590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JHS79_16600	COG4206	TonB-dependent receptor
JHS79_16605	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JHS79_16620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JHS79_16625	COG0534	Mate efflux family protein
JHS79_16630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JHS79_16635	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JHS79_16640	COG2937	Belongs to the GPAT DAPAT family
JHS79_16645	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JHS79_16650	COG3161	chorismate lyase activity
JHS79_16655	COG1580	Controls the rotational direction of flagella during chemotaxis
JHS79_16660	COG0705	Rhomboid family
JHS79_16665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHS79_16675	COG2177	Part of the ABC transporter FtsEX involved in
JHS79_16680	COG2884	Cell division ATP-binding protein ftsE
JHS79_16685	COG0552	protein localization to endoplasmic reticulum
JHS79_16690	COG0742	ribosomal rna small subunit methyltransferase
JHS79_16700	COG2095	MarC family integral membrane protein
JHS79_16750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JHS79_16755	COG0640	Transcriptional regulator
JHS79_16760	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
JHS79_16765	COG1280	lysine exporter protein (LysE YggA)
JHS79_16770	COG2267	carboxylic ester hydrolase activity
JHS79_16775	COG0561	phosphatase activity
JHS79_16790	COG3148	PFAM DTW domain containing protein
JHS79_16795	COG3287	FIST C domain
JHS79_16795	COG2199	diguanylate cyclase activity
JHS79_16795	COG2200	EAL domain
JHS79_16800	COG1011	Hydrolase
JHS79_16805	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JHS79_16815	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
JHS79_16820	COG0019	diaminopimelate decarboxylase activity
JHS79_16830	COG1965	Belongs to the frataxin family
JHS79_16835	COG3072	Adenylate cyclase
JHS79_16840	COG0181	hydroxymethylbilane synthase activity
JHS79_16845	COG1587	Uroporphyrinogen-III synthase
JHS79_16850	COG2959	enzyme of heme biosynthesis
JHS79_16855	COG3071	HemY protein
JHS79_16900	COG0633	Ferredoxin
JHS79_16905	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JHS79_16920	COG3118	belongs to the thioredoxin family
JHS79_16925	COG0513	Belongs to the DEAD box helicase family
JHS79_16930	COG0248	Ppx GppA phosphatase
JHS79_16935	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
JHS79_16945	COG0514	ATP-dependent DNA helicase (RecQ)
JHS79_16950	COG2962	Rard protein
JHS79_16960	COG1280	lysine exporter protein (LysE YggA)
JHS79_16965	COG0405	Gamma-glutamyltransferase
JHS79_16970	COG0210	DNA helicase
JHS79_16980	COG3220	belongs to the UPF0276 family
JHS79_17010	COG0006	proline dipeptidase activity
JHS79_17010	COG0006	proline dipeptidase activity
JHS79_17020	COG2022	thiamine diphosphate biosynthetic process
JHS79_17030	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JHS79_17035	COG0352	thiamine-phosphate diphosphorylase activity
JHS79_17040	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JHS79_17045	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JHS79_17060	COG3335	DDE superfamily endonuclease
JHS79_17100	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JHS79_17110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JHS79_17115	COG0408	coproporphyrinogen oxidase activity
JHS79_17120	COG0009	L-threonylcarbamoyladenylate synthase
JHS79_17125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
JHS79_17130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JHS79_17135	COG0551	DNA topoisomerase type I activity
JHS79_17140	COG2922	Belongs to the Smg family
JHS79_17145	COG0758	DNA mediated transformation
JHS79_17155	COG0242	peptide deformylase activity
JHS79_17160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JHS79_17165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JHS79_17165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JHS79_17170	COG0569	domain protein
JHS79_17175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHS79_17185	COG1272	protein, Hemolysin III
JHS79_17190	COG4326	sporulation control protein
JHS79_17200	COG3084	Protein conserved in bacteria
JHS79_17210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JHS79_17215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHS79_17220	COG0204	Acyl-transferase
JHS79_17230	COG0606	chelatase, subunit chli
JHS79_17240	COG3978	acetolactate synthase activity
JHS79_17245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JHS79_17250	COG0129	dihydroxy-acid dehydratase activity
JHS79_17260	COG0583	DNA-binding transcription factor activity
JHS79_17265	COG2814	Major facilitator Superfamily
JHS79_17270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHS79_17275	COG0765	amino acid transport
JHS79_17280	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JHS79_17285	COG0355	proton-transporting ATP synthase activity, rotational mechanism
JHS79_17290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
JHS79_17295	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
JHS79_17300	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
JHS79_17305	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
JHS79_17320	COG0356	it plays a direct role in the translocation of protons across the membrane
JHS79_17325	COG3312	ion transport
JHS79_17330	COG1475	DNA binding
JHS79_17335	COG1192	Involved in chromosome partitioning
JHS79_17340	COG0357	Ribosomal RNA small subunit methyltransferase G
JHS79_17345	COG0445	tRNA wobble uridine modification
JHS79_17350	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JHS79_17355	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JHS79_17360	COG0706	membrane insertase activity
JHS79_17370	COG0594	ribonuclease P activity
JHS79_17380	COG1126	abc transporter atp-binding protein
JHS79_17405	COG4608	Belongs to the ABC transporter superfamily
JHS79_17410	COG0444	Belongs to the ABC transporter superfamily
JHS79_17420	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
JHS79_17420	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JHS79_17440	COG0217	transcriptional regulatory protein
JHS79_17445	COG0772	Belongs to the SEDS family
JHS79_17455	COG1136	(ABC) transporter
JHS79_17475	COG3275	phosphorelay sensor kinase activity
JHS79_17480	COG3279	Response regulator of the LytR AlgR family
JHS79_17490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JHS79_17515	COG0786	glutamate:sodium symporter activity
JHS79_17525	COG1131	(ABC) transporter
JHS79_17530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHS79_17535	COG0786	glutamate:sodium symporter activity
JHS79_17545	COG0363	glucosamine-6-phosphate deaminase activity
JHS79_17565	COG1741	Belongs to the pirin family
JHS79_17570	COG2259	Doxx family
JHS79_17580	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JHS79_17585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JHS79_17595	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
JHS79_17635	COG3123	guanosine phosphorylase activity
JHS79_17645	COG5001	Diguanylate cyclase
JHS79_17650	COG0534	Mate efflux family protein
JHS79_17655	COG0564	pseudouridine synthase activity
JHS79_17670	COG0583	DNA-binding transcription factor activity
JHS79_17675	COG0561	phosphatase activity
JHS79_17685	COG2199	diguanylate cyclase activity
JHS79_17700	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JHS79_17705	COG2162	N-hydroxyarylamine O-acetyltransferase activity
JHS79_17710	COG0583	DNA-binding transcription factor activity
JHS79_17725	COG1414	Transcriptional regulator
JHS79_17730	COG1028	Short-chain dehydrogenase reductase Sdr
JHS79_17740	COG1917	Cupin 2, conserved barrel domain protein
JHS79_17755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHS79_17760	COG0800	Aldolase
JHS79_17780	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHS79_17785	COG0823	Involved in the tonB-independent uptake of proteins
JHS79_17790	COG2375	cellular response to nickel ion
JHS79_17820	COG1357	PFAM Pentapeptide repeats (8 copies)
JHS79_17825	COG3047	cAMP biosynthetic process
JHS79_17855	COG3408	Glycogen debranching enzyme
JHS79_17855	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
JHS79_17860	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
JHS79_17870	COG0583	DNA-binding transcription factor activity
JHS79_17880	COG0583	DNA-binding transcription factor activity
JHS79_17895	COG0546	phosphoglycolate phosphatase activity
JHS79_17920	COG3835	regulator
JHS79_17925	COG2610	gluconate transmembrane transporter activity
JHS79_17930	COG1929	Belongs to the glycerate kinase type-1 family
JHS79_17935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHS79_17955	COG0454	-acetyltransferase
JHS79_17955	COG0456	acetyltransferase
JHS79_17970	COG1028	Short-chain dehydrogenase reductase Sdr
JHS79_17980	COG3005	denitrification pathway
JHS79_17995	COG0352	thiamine-phosphate diphosphorylase activity
JHS79_18000	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
JHS79_18005	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JHS79_18010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JHS79_18015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JHS79_18020	COG1116	anion transmembrane transporter activity
JHS79_18025	COG0351	phosphomethylpyrimidine kinase
JHS79_18030	COG0312	modulator of DNA gyrase
JHS79_18035	COG0312	modulator of DNA gyrase
JHS79_18040	COG1901	pseudouridine methyltransferase
JHS79_18100	COG0582	viral genome integration into host DNA
JHS79_18135	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JHS79_18145	COG0584	glycerophosphoryl diester phosphodiesterase
JHS79_18150	COG0039	L-malate dehydrogenase activity
JHS79_18155	COG0745	RESPONSE REGULATOR receiver
JHS79_18175	COG0811	peptide transport
JHS79_18180	COG0811	peptide transport
JHS79_18185	COG0848	biopolymer transport protein
JHS79_18230	COG0803	Belongs to the bacterial solute-binding protein 9 family
JHS79_18235	COG1121	(ABC) transporter
JHS79_18240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JHS79_18255	COG1770	oligopeptidase
JHS79_18260	COG2814	Major facilitator Superfamily
JHS79_18265	COG0010	Belongs to the arginase family
JHS79_18270	COG1166	arginine decarboxylase activity
JHS79_18280	COG0189	ligase activity
JHS79_18280	COG4067	protein conserved in archaea
JHS79_18285	COG0189	ligase activity
JHS79_18290	COG0583	DNA-binding transcription factor activity
JHS79_18320	COG4191	Histidine kinase
JHS79_18330	COG2199	diguanylate cyclase activity
JHS79_18350	COG0579	oxidoreductase
JHS79_18360	COG3033	Beta-eliminating lyase
JHS79_18375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
JHS79_18390	COG3706	GGDEF domain
JHS79_18395	COG0840	transmembrane signaling receptor activity
JHS79_18410	COG3706	GGDEF domain
JHS79_18415	COG0415	Belongs to the DNA photolyase family
JHS79_18420	COG3046	protein related to deoxyribodipyrimidine photolyase
JHS79_18435	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHS79_18435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
JHS79_18440	COG1765	OsmC-like protein
JHS79_18445	COG0110	maltose O-acetyltransferase activity
JHS79_18485	COG1011	Hydrolase
JHS79_18500	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
JHS79_18505	COG3338	carbonate dehydratase activity
JHS79_18510	COG2067	long-chain fatty acid transport protein
JHS79_18515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHS79_18520	COG0577	efflux transmembrane transporter activity
JHS79_18520	COG1136	(ABC) transporter
JHS79_18530	COG3240	lipase activity
JHS79_18560	COG1609	Transcriptional regulator
JHS79_18565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHS79_18570	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JHS79_18580	COG1840	ABC-type Fe3 transport system, periplasmic component
JHS79_18585	COG3842	ATPase activity
JHS79_18610	COG2990	Protein conserved in bacteria
JHS79_18615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JHS79_18620	COG2866	Carboxypeptidase
JHS79_18630	COG0583	DNA-binding transcription factor activity
JHS79_18650	COG3104	oligopeptide transport
JHS79_18655	COG1760	l-serine dehydratase
JHS79_18675	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JHS79_18680	COG0741	lytic transglycosylase activity
JHS79_18700	COG1815	bacterial-type flagellum-dependent cell motility
JHS79_18705	COG1558	bacterial-type flagellum-dependent cell motility
JHS79_18710	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
JHS79_18715	COG1749	Flagellar hook protein flgE
JHS79_18720	COG4787	bacterial-type flagellum-dependent cell motility
JHS79_18725	COG4786	Flagellar basal body rod
JHS79_18730	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
JHS79_18735	COG1706	bacterial-type flagellum-dependent cell motility
JHS79_18745	COG1256	bacterial-type flagellum assembly
JHS79_18745	COG4786	Flagellar basal body rod
JHS79_18770	COG1304	FMN binding
JHS79_18785	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JHS79_18790	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JHS79_18795	COG0459	protein refolding
JHS79_18810	COG1280	lysine exporter protein (LysE YggA)
JHS79_18830	COG1309	transcriptional regulator
JHS79_18840	COG0737	Belongs to the 5'-nucleotidase family
JHS79_18845	COG2070	2-Nitropropane dioxygenase
JHS79_18850	COG3537	Alpha-1,2-mannosidase
JHS79_18855	COG3537	Alpha-1,2-mannosidase
JHS79_18865	COG3537	Alpha-1,2-mannosidase
JHS79_18870	COG3537	Alpha-1,2-mannosidase
JHS79_18875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHS79_18890	COG0346	lactoylglutathione lyase activity
JHS79_18895	COG1349	DNA-binding transcription factor activity
JHS79_18905	COG0753	catalase activity
JHS79_18915	COG1335	isochorismatase
JHS79_18925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JHS79_18950	COG0583	DNA-binding transcription factor activity
JHS79_18965	COG3713	MltA-interacting MipA family protein
JHS79_18970	COG3015	lipoprotein NlpE involved in copper resistance
JHS79_18975	COG1342	Belongs to the UPF0251 family
JHS79_19005	COG4948	Mandelate Racemase Muconate Lactonizing
JHS79_19015	COG0583	DNA-binding transcription factor activity
JHS79_19050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JHS79_19095	COG3842	ATPase activity
JHS79_19125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JHS79_19145	COG3706	GGDEF domain
JHS79_19165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHS79_19185	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JHS79_19200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JHS79_19200	COG0574	Belongs to the PEP-utilizing enzyme family
JHS79_19205	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
JHS79_19210	COG0252	asparaginase activity
JHS79_19215	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JHS79_19220	COG0583	DNA-binding transcription factor activity
JHS79_19235	COG3122	Protein conserved in bacteria
JHS79_19245	COG1028	Short-chain dehydrogenase reductase Sdr
JHS79_19255	COG1063	alcohol dehydrogenase
JHS79_19260	COG1902	pentaerythritol trinitrate reductase activity
JHS79_19275	COG0583	DNA-binding transcription factor activity
JHS79_19285	COG0513	Belongs to the DEAD box helicase family
JHS79_19310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHS79_19315	COG2207	Transcriptional regulator
JHS79_19315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JHS79_19335	COG3746	phosphate-selective porin O and P
JHS79_19350	COG1028	Short-chain dehydrogenase reductase Sdr
JHS79_19360	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
JHS79_19370	COG0625	glutathione transferase activity
JHS79_19375	COG1686	Belongs to the peptidase S11 family
JHS79_19390	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JHS79_19405	COG1278	Cold shock
JHS79_19410	COG1741	Belongs to the pirin family
JHS79_19415	COG4667	esterase of the alpha-beta hydrolase superfamily
JHS79_19440	COG2814	Major facilitator Superfamily
JHS79_19450	COG0673	inositol 2-dehydrogenase activity
JHS79_19455	COG2194	sulfuric ester hydrolase activity
JHS79_19460	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JHS79_19470	COG2205	protein histidine kinase activity
JHS79_19475	COG0745	RESPONSE REGULATOR receiver
JHS79_19480	COG4221	oxidoreductase activity
JHS79_19495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHS79_19515	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JHS79_19525	COG2814	Major facilitator Superfamily
JHS79_19535	COG1418	mRNA catabolic process
JHS79_19545	COG0402	S-adenosylhomocysteine deaminase activity
JHS79_19550	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JHS79_19555	COG2239	Acts as a magnesium transporter
JHS79_19560	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JHS79_19575	COG0531	amino acid
JHS79_19580	COG1522	sequence-specific DNA binding
JHS79_19610	COG0673	inositol 2-dehydrogenase activity
JHS79_19615	COG0534	Mate efflux family protein
JHS79_19620	COG2926	Belongs to the UPF0265 family
JHS79_19630	COG3132	Protein of unknown function, DUF480
JHS79_19635	COG2827	Endonuclease containing a URI domain
JHS79_19640	COG1879	ABC-type sugar transport system periplasmic component
JHS79_19645	COG2205	protein histidine kinase activity
JHS79_19645	COG0784	Response regulator, receiver
JHS79_19655	COG1566	PFAM secretion protein HlyD family protein
JHS79_19675	COG1522	sequence-specific DNA binding
JHS79_19700	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHS79_19705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JHS79_19715	COG1280	lysine exporter protein (LysE YggA)
JHS79_19725	COG0183	Belongs to the thiolase family
JHS79_19745	COG3005	denitrification pathway
JHS79_19755	COG0243	molybdopterin cofactor binding
JHS79_19765	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JHS79_19770	COG3850	Histidine kinase
JHS79_19775	COG2197	response regulator
JHS79_19790	COG2195	Cleaves the N-terminal amino acid of tripeptides
JHS79_19810	COG0840	transmembrane signaling receptor activity
JHS79_19820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHS79_19830	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JHS79_19835	COG2814	Major facilitator Superfamily
JHS79_19840	COG0840	transmembrane signaling receptor activity
JHS79_19845	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JHS79_19850	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JHS79_19870	COG2897	thiosulfate sulfurtransferase activity
JHS79_19890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JHS79_19900	COG0302	gtp cyclohydrolase
JHS79_19905	COG1914	H( )-stimulated, divalent metal cation uptake system
JHS79_19915	COG0038	chloride channel
JHS79_19930	COG4989	oxidoreductase activity
JHS79_19945	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JHS79_19945	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JHS79_19950	COG0516	GMP reductase activity
JHS79_19955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JHS79_20005	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JHS79_20020	COG3474	cytochrome
JHS79_20030	COG0789	Transcriptional regulator
JHS79_20035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JHS79_20040	COG0384	phenazine biosynthesis protein PhzF
JHS79_20050	COG1294	oxidase, subunit
JHS79_20055	COG1271	oxidase subunit
JHS79_20060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JHS79_20065	COG0110	maltose O-acetyltransferase activity
JHS79_20070	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
JHS79_20070	COG3264	Mechanosensitive ion channel
JHS79_20085	COG3850	Histidine kinase
JHS79_20085	COG3437	response regulator, receiver
JHS79_20085	COG2205	protein histidine kinase activity
JHS79_20085	COG4999	Histidine kinase
JHS79_20095	COG4770	biotin carboxylase activity
JHS79_20105	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JHS79_20110	COG1960	acyl-CoA dehydrogenase activity
JHS79_20120	COG0183	Belongs to the thiolase family
JHS79_20130	COG1960	acyl-CoA dehydrogenase activity
JHS79_20135	COG1024	Enoyl-CoA hydratase
JHS79_20155	COG3706	GGDEF domain
JHS79_20160	COG1309	transcriptional regulator
JHS79_20165	COG1012	belongs to the aldehyde dehydrogenase family
JHS79_20180	COG4176	ABC-type proline glycine betaine transport system permease component
JHS79_20185	COG0517	IMP dehydrogenase activity
JHS79_20185	COG4175	Glycine betaine
JHS79_20200	COG0330	HflC and HflK could
JHS79_20210	COG3300	MHYT domain
JHS79_20210	COG5001	Diguanylate cyclase
JHS79_20220	COG2205	protein histidine kinase activity
JHS79_20220	COG0784	Response regulator, receiver
JHS79_20275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JHS79_20280	COG5001	Diguanylate cyclase
JHS79_20285	COG1869	D-ribose catabolic process
JHS79_20290	COG1129	ABC transporter
JHS79_20295	COG1172	Belongs to the binding-protein-dependent transport system permease family
JHS79_20300	COG1879	ABC-type sugar transport system periplasmic component
JHS79_20305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHS79_20310	COG1609	Transcriptional regulator
JHS79_20325	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
JHS79_20335	COG4607	ABC-type enterochelin transport system periplasmic component
JHS79_20340	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHS79_20345	COG4605	iron ion homeostasis
JHS79_20350	COG4604	ABC transporter, ATP-binding protein
JHS79_20355	COG0789	Transcriptional regulator
JHS79_20365	COG1629	transport
JHS79_20365	COG4771	TonB-dependent receptor
JHS79_20395	COG1289	transmembrane transporter activity
JHS79_20400	COG0210	DNA helicase
JHS79_20405	COG1803	Methylglyoxal synthase
JHS79_20410	COG1879	ABC-type sugar transport system periplasmic component
JHS79_20415	COG2205	protein histidine kinase activity
JHS79_20415	COG2198	Histidine kinase
JHS79_20415	COG0784	Response regulator, receiver
JHS79_20430	COG0745	RESPONSE REGULATOR receiver
JHS79_20435	COG3119	arylsulfatase activity
JHS79_20440	COG3119	arylsulfatase activity
JHS79_20455	COG3119	arylsulfatase activity
JHS79_20460	COG0641	radical SAM
JHS79_20465	COG0714	Associated with various cellular activities
JHS79_20495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHS79_20495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JHS79_20500	COG0583	DNA-binding transcription factor activity
JHS79_20505	COG1597	lipid kinase activity
JHS79_20510	COG3111	PFAM Bacterial OB fold (BOF) protein
JHS79_20525	COG0641	radical SAM
JHS79_20550	COG0501	Belongs to the peptidase M48B family
JHS79_20555	COG1704	LemA family
JHS79_20560	COG3069	C4-dicarboxylate transmembrane transporter activity
JHS79_20570	COG1214	PFAM Peptidase M22, glycoprotease
JHS79_20570	COG0456	acetyltransferase
JHS79_20590	COG2076	Multidrug Resistance protein
JHS79_20620	COG0471	metal ion transport
JHS79_20625	COG3290	protein histidine kinase activity
JHS79_20630	COG4565	transcriptional regulatory protein
JHS79_20645	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JHS79_20650	COG5642	Protein of unknown function (DUF2384)
JHS79_20670	COG1902	pentaerythritol trinitrate reductase activity
JHS79_20675	COG0346	lactoylglutathione lyase activity
JHS79_20695	COG2239	Acts as a magnesium transporter
JHS79_20725	COG0242	peptide deformylase activity
JHS79_20770	COG2176	DNA-directed DNA polymerase activity
JHS79_20775	COG0583	DNA-binding transcription factor activity
JHS79_20780	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JHS79_20830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JHS79_20830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JHS79_20835	COG0509	glycine decarboxylation via glycine cleavage system
JHS79_20840	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JHS79_20880	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHS79_20880	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JHS79_20880	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHS79_20885	COG1105	Belongs to the carbohydrate kinase PfkB family
JHS79_20890	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHS79_20890	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHS79_20895	COG1609	Transcriptional regulator
JHS79_20910	COG2200	EAL domain
JHS79_20910	COG2199	diguanylate cyclase activity
JHS79_20910	COG2203	Gaf domain
JHS79_20915	COG0765	amino acid transport
JHS79_20920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHS79_20925	COG0765	amino acid transport
JHS79_20930	COG1126	abc transporter atp-binding protein
JHS79_20935	COG0469	pyruvate kinase activity
JHS79_20940	COG2271	Major facilitator Superfamily
JHS79_20965	COG1979	alcohol dehydrogenase
JHS79_20970	COG2207	Transcriptional regulator
JHS79_20980	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JHS79_20985	COG2759	Belongs to the formate--tetrahydrofolate ligase family
JHS79_20990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JHS79_21005	COG3437	response regulator, receiver
JHS79_21005	COG0784	Response regulator, receiver
JHS79_21010	COG0546	phosphoglycolate phosphatase activity
JHS79_21020	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
JHS79_21025	COG0513	Belongs to the DEAD box helicase family
JHS79_21030	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JHS79_21045	COG3038	cytochrome b561
JHS79_21050	COG2353	YceI-like domain
JHS79_21055	COG2116	formate transmembrane transporter activity
JHS79_21060	COG0583	DNA-binding transcription factor activity
JHS79_21070	COG3593	DNA synthesis involved in DNA repair
JHS79_21075	COG0737	Belongs to the 5'-nucleotidase family
JHS79_21080	COG0861	Integral membrane protein TerC family
JHS79_21095	COG2267	carboxylic ester hydrolase activity
JHS79_21100	COG2067	long-chain fatty acid transport protein
JHS79_21115	COG2050	protein possibly involved in aromatic compounds catabolism
JHS79_21125	COG4533	DNA binding
JHS79_21150	COG0484	heat shock protein binding
JHS79_21160	COG3300	MHYT domain
JHS79_21160	COG5001	Diguanylate cyclase
JHS79_21165	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JHS79_21175	COG4181	ATPase activity
JHS79_21180	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JHS79_21190	COG1984	allophanate hydrolase subunit 2
JHS79_21195	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JHS79_21200	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
JHS79_21205	COG3447	MASE1 domain protein
JHS79_21205	COG5001	Diguanylate cyclase
JHS79_21205	COG5002	protein histidine kinase activity
JHS79_21210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JHS79_21215	COG4771	TonB-dependent receptor
JHS79_21215	COG1629	transport
JHS79_21220	COG0583	DNA-binding transcription factor activity
JHS79_21225	COG0045	succinate-CoA ligase (ADP-forming) activity
JHS79_21225	COG1042	CoA-binding domain protein
JHS79_21225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHS79_21235	COG1181	Belongs to the D-alanine--D-alanine ligase family
JHS79_21245	COG0023	Translation Initiation Factor
JHS79_21560	COG0583	DNA-binding transcription factor activity
JHS79_21570	COG0589	response to stress
JHS79_21575	COG3140	Belongs to the UPF0181 family
JHS79_21600	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
JHS79_21605	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JHS79_21630	COG2203	Gaf domain
JHS79_21630	COG3706	GGDEF domain
JHS79_21630	COG5001	Diguanylate cyclase
JHS79_21630	COG4251	negative regulation of phosphorylation
JHS79_21640	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JHS79_21645	COG4149	molybdate abc transporter
JHS79_21650	COG0725	ABC transporter, periplasmic molybdate-binding protein
JHS79_21655	COG1492	cobalamin metabolic process
JHS79_21660	COG3111	PFAM Bacterial OB fold (BOF) protein
JHS79_21670	COG4067	protein conserved in archaea
JHS79_21670	COG0189	ligase activity
JHS79_21685	COG0534	Mate efflux family protein
JHS79_21690	COG0602	queuosine metabolic process
JHS79_21695	COG1328	CTP reductase activity
JHS79_21710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHS79_21740	COG0243	molybdopterin cofactor binding
JHS79_21745	COG0583	DNA-binding transcription factor activity
JHS79_21750	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JHS79_21760	COG2197	response regulator
JHS79_21765	COG3851	Histidine kinase
JHS79_21770	COG2271	Major facilitator Superfamily
JHS79_21795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JHS79_21800	COG3118	belongs to the thioredoxin family
JHS79_21810	COG3292	Two component regulator propeller
JHS79_21810	COG0745	RESPONSE REGULATOR receiver
JHS79_21810	COG2205	protein histidine kinase activity
JHS79_21815	COG0534	Mate efflux family protein
JHS79_21845	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
JHS79_21865	COG2116	formate transmembrane transporter activity
JHS79_21875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JHS79_21880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JHS79_21915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JHS79_21915	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JHS79_21955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JHS79_21970	COG0277	FAD linked oxidase domain protein
JHS79_21975	COG0583	DNA-binding transcription factor activity
JHS79_21990	COG2425	protein containing a von Willebrand factor type A (vWA) domain
JHS79_22005	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
JHS79_22015	COG1288	antiporter activity
JHS79_22025	COG0671	phosphoesterase, PA-phosphatase related
JHS79_22035	COG2962	Rard protein
JHS79_22050	COG0835	chemotaxis
JHS79_22050	COG0784	Response regulator, receiver
JHS79_22070	COG2197	response regulator
JHS79_22080	COG3706	GGDEF domain
JHS79_22085	COG2197	response regulator
JHS79_22090	COG3300	MHYT domain
JHS79_22090	COG5001	Diguanylate cyclase
JHS79_22105	COG0583	DNA-binding transcription factor activity
JHS79_22120	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
JHS79_22145	COG2814	Major facilitator Superfamily
JHS79_22155	COG3040	lipid binding
JHS79_22175	COG0419	ATPase involved in DNA repair
JHS79_22180	COG0420	3'-5' exonuclease activity
JHS79_22250	COG0631	protein serine/threonine phosphatase activity
JHS79_22285	COG0515	serine threonine protein kinase
JHS79_22285	COG2815	serine threonine protein kinase
JHS79_22340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JHS79_22340	COG2146	nitrite reductase [NAD(P)H] activity
JHS79_22345	COG1116	anion transmembrane transporter activity
JHS79_22350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JHS79_22355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JHS79_22360	COG3707	response regulator
JHS79_22375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JHS79_22375	COG1648	precorrin-2 dehydrogenase activity
JHS79_22380	COG0243	molybdopterin cofactor binding
JHS79_22390	COG0814	amino acid
JHS79_22415	COG1785	Belongs to the alkaline phosphatase family
JHS79_22430	COG0745	RESPONSE REGULATOR receiver
JHS79_22455	COG2847	Copper chaperone PCu(A)C
JHS79_22460	COG0443	Heat shock 70 kDa protein
JHS79_22495	COG0625	glutathione transferase activity
JHS79_22510	COG4160	amino acid transport
JHS79_22515	COG4215	(ABC) transporter
JHS79_22520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHS79_22525	COG1126	abc transporter atp-binding protein
JHS79_22535	COG1902	pentaerythritol trinitrate reductase activity
JHS79_22545	COG0109	protoheme IX farnesyltransferase activity
JHS79_22550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JHS79_22555	COG1845	cytochrome c oxidase, subunit III
JHS79_22560	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JHS79_22565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JHS79_22570	COG1028	Short-chain dehydrogenase reductase Sdr
JHS79_22580	COG1024	Enoyl-CoA hydratase
JHS79_22585	COG1024	Enoyl-CoA hydratase
JHS79_22600	COG0183	Belongs to the thiolase family
JHS79_22610	COG1960	acyl-CoA dehydrogenase activity
JHS79_22615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JHS79_22620	COG1024	Enoyl-CoA hydratase
JHS79_22630	COG5413	integral membrane protein
JHS79_22645	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JHS79_22650	COG5001	Diguanylate cyclase
JHS79_22655	COG0513	Belongs to the DEAD box helicase family
JHS79_22660	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
JHS79_22675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JHS79_22695	COG0641	radical SAM
JHS79_22715	COG0840	transmembrane signaling receptor activity
JHS79_22720	COG1119	ATPase activity
JHS79_22725	COG2200	EAL domain
JHS79_22745	COG0513	Belongs to the DEAD box helicase family
JHS79_22750	COG0523	cobalamin synthesis protein
JHS79_22760	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JHS79_22770	COG0133	tryptophan synthase activity
JHS79_22775	COG4628	conserved protein (DUF2132)
JHS79_22780	COG0513	Belongs to the DEAD box helicase family
JHS79_22785	COG3530	Putative quorum-sensing-regulated virulence factor
JHS79_22805	COG2154	pterin-4-alpha-carbinolamine dehydratase
JHS79_22810	COG3186	Phenylalanine-4-hydroxylase
JHS79_22815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JHS79_22820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JHS79_22860	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JHS79_22865	COG1454	alcohol dehydrogenase
JHS79_22870	COG2133	pyrroloquinoline quinone binding
JHS79_22880	COG0783	Belongs to the Dps family
JHS79_22885	COG0840	transmembrane signaling receptor activity
JHS79_22895	COG0577	efflux transmembrane transporter activity
JHS79_22895	COG1136	(ABC) transporter
JHS79_22915	COG2199	diguanylate cyclase activity
JHS79_22925	COG3036	rescue of stalled ribosome
JHS79_22930	COG1278	Cold shock
JHS79_22960	COG0545	Peptidyl-prolyl cis-trans isomerase
JHS79_22965	COG0109	protoheme IX farnesyltransferase activity
JHS79_22970	COG1612	heme a metabolic process
JHS79_22995	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
JHS79_23005	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JHS79_23010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JHS79_23020	COG1280	lysine exporter protein (LysE YggA)
JHS79_23025	COG2207	Transcriptional regulator
JHS79_23050	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
JHS79_23055	COG0697	spore germination
JHS79_23070	COG2814	Major facilitator Superfamily
JHS79_23075	COG0583	DNA-binding transcription factor activity
JHS79_23080	COG5001	Diguanylate cyclase
JHS79_23085	COG0739	heme binding
JHS79_23105	COG3314	Sporulation integral membrane protein YlbJ
JHS79_23120	COG0814	amino acid
JHS79_23140	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JHS79_23145	COG1072	(Pantothenic acid kinase))
JHS79_23155	COG1063	alcohol dehydrogenase
JHS79_23160	COG2213	PTS system mannitol-specific
JHS79_23165	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHS79_23170	COG0747	negative chemotaxis
JHS79_23180	COG0798	PFAM Bile acid sodium symporter
JHS79_23190	COG1881	PFAM PEBP family protein
JHS79_23200	COG2706	6-phosphogluconolactonase activity
JHS79_23215	COG1131	(ABC) transporter
JHS79_23220	COG0842	Transport permease protein
JHS79_23235	COG3383	formate dehydrogenase (NAD+) activity
JHS79_23255	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JHS79_23285	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JHS79_23295	COG2067	long-chain fatty acid transport protein
JHS79_23305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JHS79_23315	COG1505	serine-type exopeptidase activity
JHS79_23320	COG0488	(ABC) transporter
JHS79_23325	COG0589	response to stress
JHS79_23330	COG2249	NAD(P)H dehydrogenase (quinone) activity
JHS79_23350	COG0366	Alpha amylase catalytic
JHS79_23360	COG4934	collagen metabolic process
JHS79_23375	COG0583	DNA-binding transcription factor activity
JHS79_23380	COG0783	Belongs to the Dps family
JHS79_23385	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
JHS79_23440	COG2814	Major facilitator Superfamily
JHS79_23490	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JHS79_23495	COG0835	chemotaxis
JHS79_23495	COG0784	Response regulator, receiver
JHS79_23505	COG0748	coenzyme F420 binding
JHS79_23510	COG3721	Heme iron utilization protein
JHS79_23520	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JHS79_23525	COG0811	peptide transport
JHS79_23530	COG0848	biopolymer transport protein
JHS79_23540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHS79_23545	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JHS79_23585	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JHS79_23590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JHS79_23595	COG3217	Mosc domain protein beta barrel domain protein
JHS79_23595	COG0633	Ferredoxin
JHS79_23595	COG3217	Mosc domain protein beta barrel domain protein
JHS79_23595	COG0633	Ferredoxin
JHS79_23600	COG0401	homolog of Blt101
JHS79_23605	COG0418	dihydroorotase activity
JHS79_23610	COG2354	Protein conserved in bacteria
JHS79_23640	COG3833	ABC-type maltose transport systems, permease component
JHS79_23645	COG1175	transmembrane transport
JHS79_23655	COG3842	ATPase activity
JHS79_23660	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JHS79_23715	COG3097	Belongs to the UPF0267 family
JHS79_23720	COG1309	transcriptional regulator
JHS79_23725	COG2130	NADP-dependent
JHS79_23735	COG0753	catalase activity
JHS79_23740	COG2084	Dehydrogenase
JHS79_23745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHS79_23750	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHS79_23760	COG2207	Transcriptional regulator
JHS79_23765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHS79_23765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JHS79_23765	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
JHS79_23780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JHS79_23785	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
JHS79_23790	COG5001	Diguanylate cyclase
JHS79_23790	COG3300	MHYT domain
JHS79_23795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JHS79_23800	COG0569	domain protein
JHS79_23810	COG2205	protein histidine kinase activity
JHS79_23810	COG2205	protein histidine kinase activity
JHS79_23815	COG1132	(ABC) transporter
JHS79_23820	COG4774	siderophore transport
JHS79_23825	COG1120	ATPase activity
JHS79_23830	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JHS79_23865	COG2197	response regulator
JHS79_23875	COG0840	transmembrane signaling receptor activity
JHS79_23880	COG0714	Associated with various cellular activities
JHS79_23900	COG2304	oxidoreductase activity
JHS79_23915	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JHS79_23920	COG0581	inorganic phosphate transmembrane transporter activity
JHS79_23925	COG0573	inorganic phosphate transmembrane transporter activity
JHS79_23955	COG4771	TonB-dependent receptor
JHS79_23960	COG1770	oligopeptidase
JHS79_23965	COG0513	Belongs to the DEAD box helicase family
JHS79_23975	COG1376	ErfK ybiS ycfS ynhG family protein
JHS79_23975	COG1388	LysM domain
JHS79_23980	COG0415	Belongs to the DNA photolyase family
JHS79_23985	COG0789	Transcriptional regulator
JHS79_23990	COG3272	Protein of unknown function (DUF1722)
JHS79_23995	COG0813	purine-nucleoside phosphorylase activity
JHS79_24010	COG3706	GGDEF domain
JHS79_24020	COG1566	PFAM secretion protein HlyD family protein
JHS79_24025	COG4720	Psort location CytoplasmicMembrane, score
JHS79_24030	COG1122	ATPase activity
JHS79_24045	COG0348	domain, Protein
JHS79_24050	COG0437	4 iron, 4 sulfur cluster binding
JHS79_24055	COG1247	-acetyltransferase
JHS79_24080	COG1067	ATP-dependent peptidase activity
JHS79_24090	COG4172	Belongs to the ABC transporter superfamily
JHS79_24095	COG1505	serine-type exopeptidase activity
JHS79_24100	COG0583	DNA-binding transcription factor activity
JHS79_24105	COG1620	l-lactate permease
JHS79_24110	COG1304	FMN binding
JHS79_24120	COG0668	transmembrane transport
JHS79_24155	COG1063	alcohol dehydrogenase
JHS79_24160	COG0156	8-amino-7-oxononanoate synthase activity
JHS79_24170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JHS79_24190	COG0745	RESPONSE REGULATOR receiver
JHS79_24215	COG0346	lactoylglutathione lyase activity
JHS79_24235	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JHS79_24315	COG1987	bacterial-type flagellum assembly
JHS79_24325	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
JHS79_24340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
JHS79_24355	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
JHS79_24360	COG1516	flagellar protein fliS
JHS79_24375	COG1580	Controls the rotational direction of flagella during chemotaxis
JHS79_24380	COG1191	sigma factor activity
JHS79_24385	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
JHS79_24390	COG1360	Flagellar Motor Protein
JHS79_24435	COG1882	Formate acetyltransferase
JHS79_24440	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JHS79_24445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JHS79_24455	COG0454	-acetyltransferase
JHS79_24470	COG2814	Major facilitator Superfamily
JHS79_24510	COG0628	permease
JHS79_24525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JHS79_24535	COG4628	conserved protein (DUF2132)
JHS79_24540	COG0583	DNA-binding transcription factor activity
JHS79_24565	COG1686	Belongs to the peptidase S11 family
JHS79_24580	COG1054	Belongs to the UPF0176 family
JHS79_24585	COG3397	chitin binding
JHS79_24590	COG4667	esterase of the alpha-beta hydrolase superfamily
JHS79_24595	COG2095	MarC family integral membrane protein
JHS79_24620	COG0583	DNA-binding transcription factor activity
JHS79_24630	COG1301	dicarboxylic acid transport
JHS79_24635	COG3339	Conserved Protein
JHS79_24640	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JHS79_24645	COG0700	Nucleoside recognition
JHS79_24650	COG3366	ferrous iron transmembrane transporter activity
JHS79_24665	COG0366	Alpha amylase catalytic
JHS79_24670	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JHS79_24675	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
JHS79_24680	COG1640	4-alpha-glucanotransferase
JHS79_24685	COG0058	SHG alpha-glucan phosphorylase activity
JHS79_24690	COG2909	trisaccharide binding
JHS79_24705	COG1999	signal sequence binding
JHS79_24715	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHS79_24715	COG1263	PTS System
JHS79_24720	COG1162	GTPase activity
JHS79_24725	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
JHS79_24735	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
JHS79_24745	COG0531	amino acid
JHS79_24750	COG1982	Orn Lys Arg decarboxylase major
JHS79_24770	COG2356	endonuclease I
JHS79_24790	COG4580	involved in the transport of maltose and maltodextrins
JHS79_24815	COG0739	heme binding
JHS79_24825	COG0612	Peptidase, M16
JHS79_24830	COG0840	transmembrane signaling receptor activity
JHS79_24835	COG1120	ATPase activity
JHS79_24840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHS79_24845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JHS79_24850	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
JHS79_24855	COG4772	TonB-dependent receptor
JHS79_24880	COG4264	IucA IucC family
JHS79_24885	COG0019	diaminopimelate decarboxylase activity
JHS79_24890	COG1653	transport
JHS79_24915	COG0826	peptidase U32
JHS79_24920	COG1172	Belongs to the binding-protein-dependent transport system permease family
JHS79_24925	COG1129	ABC transporter
JHS79_24930	COG1879	ABC-type sugar transport system periplasmic component
JHS79_24935	COG1069	ribulokinase activity
JHS79_24945	COG2160	L-arabinose isomerase activity
JHS79_24970	COG1764	response to oxidative stress
JHS79_24975	COG1846	Transcriptional regulator
JHS79_24985	COG3634	alkyl hydroperoxide reductase activity
JHS79_25020	COG1595	DNA-templated transcription, initiation
JHS79_25035	COG0583	DNA-binding transcription factor activity
JHS79_25040	COG1486	melibiose metabolic process
JHS79_25055	COG2258	MOSC domain
JHS79_25060	COG0513	Belongs to the DEAD box helicase family
JHS79_25085	COG1132	(ABC) transporter
JHS79_25130	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JHS79_25155	COG0259	pyridoxamine-phosphate oxidase activity
JHS79_25200	COG4166	transmembrane transport
JHS79_25215	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
JHS79_25220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
JHS79_25220	COG1263	PTS System
JHS79_25230	COG3340	Belongs to the peptidase S51 family
JHS79_25250	COG1444	tRNA N-acetyltransferase activity
JHS79_25315	COG2003	Belongs to the UPF0758 family
JHS79_25360	COG1192	Involved in chromosome partitioning
JHS79_25425	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
JHS79_25445	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JHS79_25510	COG3829	transcription factor binding
JHS79_25545	COG3501	Rhs element vgr protein
JHS79_25555	COG3675	Pfam Lipase (class 3)
JHS79_25585	COG0768	penicillin binding
JHS79_25685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHS79_25790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHS79_25830	COG0776	regulation of translation
JHS79_25950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JHS79_26090	COG2885	chlorophyll binding
JHS79_26150	COG1192	Involved in chromosome partitioning
JHS79_26170	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
JHS79_26200	COG5268	conjugation
JHS79_26205	COG3451	type IV secretory pathway VirB4
JHS79_26215	COG4962	Type ii secretion system protein e
JHS79_26235	COG3504	Conjugal transfer protein
JHS79_26245	COG2948	multi-organism process
JHS79_26275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JHS79_26390	COG1192	Involved in chromosome partitioning
JHS79_26485	COG0740	serine-type endopeptidase activity