locus-tag	class	description
FKM99_00010	COG0444	Belongs to the ABC transporter superfamily
FKM99_00015	COG4608	Belongs to the ABC transporter superfamily
FKM99_00040	COG1444	tRNA N-acetyltransferase activity
FKM99_00060	COG3340	Belongs to the peptidase S51 family
FKM99_00065	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKM99_00070	COG1263	PTS System
FKM99_00070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FKM99_00075	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FKM99_00095	COG4166	transmembrane transport
FKM99_00140	COG0259	pyridoxamine-phosphate oxidase activity
FKM99_00170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FKM99_00215	COG1132	(ABC) transporter
FKM99_00225	COG2207	Transcriptional regulator
FKM99_00250	COG0800	Aldolase
FKM99_00255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKM99_00260	COG1904	glucuronate isomerase
FKM99_00265	COG0246	Mannitol dehydrogenase
FKM99_00275	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FKM99_00285	COG2186	Transcriptional regulator
FKM99_00290	COG1312	Catalyzes the dehydration of D-mannonate
FKM99_00295	COG0513	Belongs to the DEAD box helicase family
FKM99_00300	COG2258	MOSC domain
FKM99_00315	COG1486	melibiose metabolic process
FKM99_00320	COG0583	DNA-binding transcription factor activity
FKM99_00325	COG0840	transmembrane signaling receptor activity
FKM99_00340	COG1595	DNA-templated transcription, initiation
FKM99_00380	COG3634	alkyl hydroperoxide reductase activity
FKM99_00385	COG0450	alkyl hydroperoxide reductase
FKM99_00390	COG1846	Transcriptional regulator
FKM99_00395	COG1764	response to oxidative stress
FKM99_00420	COG2160	L-arabinose isomerase activity
FKM99_00430	COG1069	ribulokinase activity
FKM99_00435	COG1879	ABC-type sugar transport system periplasmic component
FKM99_00440	COG1129	ABC transporter
FKM99_00445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FKM99_00470	COG0745	RESPONSE REGULATOR receiver
FKM99_00480	COG1653	transport
FKM99_00485	COG0019	diaminopimelate decarboxylase activity
FKM99_00490	COG4264	IucA IucC family
FKM99_00495	COG2814	Major facilitator Superfamily
FKM99_00515	COG4772	TonB-dependent receptor
FKM99_00520	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FKM99_00525	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FKM99_00530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FKM99_00535	COG1120	ATPase activity
FKM99_00540	COG0840	transmembrane signaling receptor activity
FKM99_00545	COG0612	Peptidase, M16
FKM99_00555	COG0739	heme binding
FKM99_00565	COG2814	Major facilitator Superfamily
FKM99_00605	COG2356	endonuclease I
FKM99_00625	COG1982	Orn Lys Arg decarboxylase major
FKM99_00630	COG0531	amino acid
FKM99_00640	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FKM99_00650	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FKM99_00655	COG1162	GTPase activity
FKM99_00660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FKM99_00660	COG1263	PTS System
FKM99_00670	COG1999	signal sequence binding
FKM99_00685	COG2909	trisaccharide binding
FKM99_00700	COG0058	SHG alpha-glucan phosphorylase activity
FKM99_00705	COG1640	4-alpha-glucanotransferase
FKM99_00710	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FKM99_00840	COG0484	heat shock protein binding
FKM99_00995	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FKM99_01000	COG0366	Alpha amylase catalytic
FKM99_01015	COG3366	ferrous iron transmembrane transporter activity
FKM99_01020	COG0700	Nucleoside recognition
FKM99_01025	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FKM99_01030	COG3339	Conserved Protein
FKM99_01035	COG1301	dicarboxylic acid transport
FKM99_01045	COG0583	DNA-binding transcription factor activity
FKM99_01065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FKM99_01070	COG1596	polysaccharide export
FKM99_01085	COG2095	MarC family integral membrane protein
FKM99_01090	COG4667	esterase of the alpha-beta hydrolase superfamily
FKM99_01095	COG3397	chitin binding
FKM99_01115	COG1686	Belongs to the peptidase S11 family
FKM99_01140	COG0583	DNA-binding transcription factor activity
FKM99_01145	COG4628	conserved protein (DUF2132)
FKM99_01155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FKM99_01165	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FKM99_01170	COG0628	permease
FKM99_01215	COG2814	Major facilitator Superfamily
FKM99_01225	COG0454	-acetyltransferase
FKM99_01235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FKM99_01240	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FKM99_01295	COG1360	Flagellar Motor Protein
FKM99_01300	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FKM99_01305	COG1191	sigma factor activity
FKM99_01310	COG1580	Controls the rotational direction of flagella during chemotaxis
FKM99_01325	COG1516	flagellar protein fliS
FKM99_01330	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FKM99_01340	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FKM99_01355	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FKM99_01365	COG1987	bacterial-type flagellum assembly
FKM99_01390	COG2204	response regulator
FKM99_01405	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FKM99_01445	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FKM99_01465	COG0346	lactoylglutathione lyase activity
FKM99_01500	COG0745	RESPONSE REGULATOR receiver
FKM99_01520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKM99_01530	COG0156	8-amino-7-oxononanoate synthase activity
FKM99_01535	COG1063	alcohol dehydrogenase
FKM99_01570	COG0668	transmembrane transport
FKM99_01580	COG1304	FMN binding
FKM99_01585	COG1620	l-lactate permease
FKM99_01590	COG0583	DNA-binding transcription factor activity
FKM99_01595	COG1505	serine-type exopeptidase activity
FKM99_01600	COG4172	Belongs to the ABC transporter superfamily
FKM99_01610	COG1067	ATP-dependent peptidase activity
FKM99_01640	COG1247	-acetyltransferase
FKM99_01645	COG0437	4 iron, 4 sulfur cluster binding
FKM99_01650	COG0348	domain, Protein
FKM99_01665	COG1122	ATPase activity
FKM99_01670	COG4720	Psort location CytoplasmicMembrane, score
FKM99_01675	COG1566	PFAM secretion protein HlyD family protein
FKM99_01685	COG3706	GGDEF domain
FKM99_01700	COG0813	purine-nucleoside phosphorylase activity
FKM99_01710	COG3272	Protein of unknown function (DUF1722)
FKM99_01715	COG0789	Transcriptional regulator
FKM99_01720	COG0415	Belongs to the DNA photolyase family
FKM99_01725	COG1388	LysM domain
FKM99_01725	COG1376	ErfK ybiS ycfS ynhG family protein
FKM99_01735	COG0513	Belongs to the DEAD box helicase family
FKM99_01740	COG1770	oligopeptidase
FKM99_01745	COG4771	TonB-dependent receptor
FKM99_01770	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FKM99_01775	COG0573	inorganic phosphate transmembrane transporter activity
FKM99_01780	COG0581	inorganic phosphate transmembrane transporter activity
FKM99_01785	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FKM99_01800	COG2304	oxidoreductase activity
FKM99_01820	COG0714	Associated with various cellular activities
FKM99_01830	COG0840	transmembrane signaling receptor activity
FKM99_01840	COG2197	response regulator
FKM99_01875	COG2885	chlorophyll binding
FKM99_01875	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FKM99_01890	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
FKM99_01895	COG1120	ATPase activity
FKM99_01900	COG4774	siderophore transport
FKM99_01905	COG1132	(ABC) transporter
FKM99_01910	COG5002	protein histidine kinase activity
FKM99_01920	COG0569	domain protein
FKM99_01925	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FKM99_01935	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
FKM99_01940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FKM99_01955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FKM99_01955	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FKM99_01955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FKM99_01960	COG2207	Transcriptional regulator
FKM99_01970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FKM99_01975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FKM99_01980	COG2084	Dehydrogenase
FKM99_01985	COG0753	catalase activity
FKM99_01995	COG2130	NADP-dependent
FKM99_02000	COG1309	transcriptional regulator
FKM99_02065	COG3842	ATPase activity
FKM99_02075	COG1175	transmembrane transport
FKM99_02080	COG3833	ABC-type maltose transport systems, permease component
FKM99_02110	COG2354	Protein conserved in bacteria
FKM99_02115	COG0418	dihydroorotase activity
FKM99_02125	COG0401	homolog of Blt101
FKM99_02135	COG0633	Ferredoxin
FKM99_02135	COG0633	Ferredoxin
FKM99_02135	COG3217	Mosc domain protein beta barrel domain protein
FKM99_02135	COG3217	Mosc domain protein beta barrel domain protein
FKM99_02140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FKM99_02145	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FKM99_02190	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FKM99_02195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FKM99_02205	COG0848	biopolymer transport protein
FKM99_02210	COG0811	peptide transport
FKM99_02215	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FKM99_02225	COG3721	Heme iron utilization protein
FKM99_02230	COG0748	coenzyme F420 binding
FKM99_02240	COG0784	Response regulator, receiver
FKM99_02240	COG0835	chemotaxis
FKM99_02250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FKM99_02275	COG1201	RNA secondary structure unwinding
FKM99_02300	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FKM99_02305	COG0783	Belongs to the Dps family
FKM99_02315	COG0583	DNA-binding transcription factor activity
FKM99_02330	COG4934	collagen metabolic process
FKM99_02340	COG0366	Alpha amylase catalytic
FKM99_02360	COG2249	NAD(P)H dehydrogenase (quinone) activity
FKM99_02365	COG0589	response to stress
FKM99_02375	COG1505	serine-type exopeptidase activity
FKM99_02385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKM99_02395	COG2067	long-chain fatty acid transport protein
FKM99_02405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FKM99_02415	COG2199	diguanylate cyclase activity
FKM99_02415	COG2203	Gaf domain
FKM99_02435	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKM99_02460	COG3383	formate dehydrogenase (NAD+) activity
FKM99_02475	COG0842	Transport permease protein
FKM99_02480	COG1131	(ABC) transporter
FKM99_02500	COG2706	6-phosphogluconolactonase activity
FKM99_02510	COG1881	PFAM PEBP family protein
FKM99_02520	COG0798	PFAM Bile acid sodium symporter
FKM99_02540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FKM99_02545	COG2213	PTS system mannitol-specific
FKM99_02550	COG1063	alcohol dehydrogenase
FKM99_02560	COG1072	(Pantothenic acid kinase))
FKM99_02565	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FKM99_02585	COG0814	amino acid
FKM99_02625	COG0739	heme binding
FKM99_02630	COG5001	Diguanylate cyclase
FKM99_02635	COG0583	DNA-binding transcription factor activity
FKM99_02640	COG2814	Major facilitator Superfamily
FKM99_02665	COG0697	spore germination
FKM99_02695	COG2207	Transcriptional regulator
FKM99_02700	COG1280	lysine exporter protein (LysE YggA)
FKM99_02710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FKM99_02715	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FKM99_02725	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FKM99_02750	COG1612	heme a metabolic process
FKM99_02755	COG0109	protoheme IX farnesyltransferase activity
FKM99_02760	COG0545	Peptidyl-prolyl cis-trans isomerase
FKM99_02795	COG1278	Cold shock
FKM99_02800	COG3036	rescue of stalled ribosome
FKM99_02815	COG2199	diguanylate cyclase activity
FKM99_02835	COG0577	efflux transmembrane transporter activity
FKM99_02835	COG1136	(ABC) transporter
FKM99_02845	COG0840	transmembrane signaling receptor activity
FKM99_02850	COG0783	Belongs to the Dps family
FKM99_02860	COG2133	pyrroloquinoline quinone binding
FKM99_02865	COG1454	alcohol dehydrogenase
FKM99_02870	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FKM99_02905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FKM99_02910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FKM99_02915	COG3186	Phenylalanine-4-hydroxylase
FKM99_02920	COG2154	pterin-4-alpha-carbinolamine dehydratase
FKM99_02945	COG3530	Putative quorum-sensing-regulated virulence factor
FKM99_02950	COG0513	Belongs to the DEAD box helicase family
FKM99_02955	COG4628	conserved protein (DUF2132)
FKM99_02960	COG0133	tryptophan synthase activity
FKM99_02970	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FKM99_02980	COG0523	cobalamin synthesis protein
FKM99_02985	COG0513	Belongs to the DEAD box helicase family
FKM99_03005	COG2200	EAL domain
FKM99_03010	COG1119	ATPase activity
FKM99_03015	COG0840	transmembrane signaling receptor activity
FKM99_03040	COG0641	radical SAM
FKM99_03060	COG0515	serine threonine protein kinase
FKM99_03060	COG2815	serine threonine protein kinase
FKM99_03065	COG0515	serine threonine protein kinase
FKM99_03095	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FKM99_03110	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FKM99_03115	COG0513	Belongs to the DEAD box helicase family
FKM99_03120	COG5001	Diguanylate cyclase
FKM99_03130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FKM99_03145	COG5413	integral membrane protein
FKM99_03155	COG1024	Enoyl-CoA hydratase
FKM99_03160	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FKM99_03165	COG1960	acyl-CoA dehydrogenase activity
FKM99_03175	COG0183	Belongs to the thiolase family
FKM99_03190	COG1024	Enoyl-CoA hydratase
FKM99_03195	COG1024	Enoyl-CoA hydratase
FKM99_03205	COG1028	Short-chain dehydrogenase reductase Sdr
FKM99_03210	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FKM99_03215	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FKM99_03220	COG1845	cytochrome c oxidase, subunit III
FKM99_03225	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FKM99_03230	COG0109	protoheme IX farnesyltransferase activity
FKM99_03245	COG1902	pentaerythritol trinitrate reductase activity
FKM99_03280	COG1126	abc transporter atp-binding protein
FKM99_03285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKM99_03290	COG4215	(ABC) transporter
FKM99_03295	COG4160	amino acid transport
FKM99_03310	COG0625	glutathione transferase activity
FKM99_03345	COG0443	Heat shock 70 kDa protein
FKM99_03350	COG2847	Copper chaperone PCu(A)C
FKM99_03380	COG0745	RESPONSE REGULATOR receiver
FKM99_03415	COG3706	GGDEF domain
FKM99_03415	COG0745	RESPONSE REGULATOR receiver
FKM99_03425	COG0814	amino acid
FKM99_03430	COG0456	acetyltransferase
FKM99_03435	COG0243	molybdopterin cofactor binding
FKM99_03460	COG3707	response regulator
FKM99_03470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FKM99_03470	COG1116	anion transmembrane transporter activity
FKM99_03475	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKM99_03480	COG1116	anion transmembrane transporter activity
FKM99_03485	COG2146	nitrite reductase [NAD(P)H] activity
FKM99_03485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FKM99_03540	COG2815	serine threonine protein kinase
FKM99_03540	COG0515	serine threonine protein kinase
FKM99_03575	COG0631	protein serine/threonine phosphatase activity
FKM99_03630	COG3501	Rhs element vgr protein
FKM99_03645	COG0420	3'-5' exonuclease activity
FKM99_03650	COG0419	ATPase involved in DNA repair
FKM99_03655	COG3328	transposase activity
FKM99_03675	COG3040	lipid binding
FKM99_03685	COG2814	Major facilitator Superfamily
FKM99_03695	COG1288	antiporter activity
FKM99_03710	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FKM99_03725	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FKM99_03745	COG0583	DNA-binding transcription factor activity
FKM99_03750	COG0277	FAD linked oxidase domain protein
FKM99_03770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FKM99_03855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FKM99_03860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FKM99_03865	COG2146	nitrite reductase [NAD(P)H] activity
FKM99_03870	COG2116	formate transmembrane transporter activity
FKM99_03890	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FKM99_03925	COG0534	Mate efflux family protein
FKM99_03935	COG2814	Major facilitator Superfamily
FKM99_03940	COG3118	belongs to the thioredoxin family
FKM99_03945	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FKM99_03970	COG2271	Major facilitator Superfamily
FKM99_03975	COG3851	Histidine kinase
FKM99_03980	COG2197	response regulator
FKM99_03990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FKM99_03995	COG0583	DNA-binding transcription factor activity
FKM99_04005	COG0243	molybdopterin cofactor binding
FKM99_04035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKM99_04050	COG1328	CTP reductase activity
FKM99_04055	COG0602	queuosine metabolic process
FKM99_04060	COG0534	Mate efflux family protein
FKM99_04080	COG0189	ligase activity
FKM99_04080	COG4067	protein conserved in archaea
FKM99_04090	COG3111	PFAM Bacterial OB fold (BOF) protein
FKM99_04095	COG1492	cobalamin metabolic process
FKM99_04100	COG0725	ABC transporter, periplasmic molybdate-binding protein
FKM99_04105	COG4149	molybdate abc transporter
FKM99_04110	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FKM99_04120	COG3706	GGDEF domain
FKM99_04120	COG5001	Diguanylate cyclase
FKM99_04120	COG4251	negative regulation of phosphorylation
FKM99_04120	COG2203	Gaf domain
FKM99_04130	COG0745	RESPONSE REGULATOR receiver
FKM99_04130	COG3706	GGDEF domain
FKM99_04145	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FKM99_04150	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FKM99_04175	COG3140	Belongs to the UPF0181 family
FKM99_04180	COG0589	response to stress
FKM99_04210	COG0023	Translation Initiation Factor
FKM99_04220	COG1181	Belongs to the D-alanine--D-alanine ligase family
FKM99_04230	COG0045	succinate-CoA ligase (ADP-forming) activity
FKM99_04230	COG1042	CoA-binding domain protein
FKM99_04230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FKM99_04235	COG0583	DNA-binding transcription factor activity
FKM99_04240	COG4771	TonB-dependent receptor
FKM99_04240	COG1629	transport
FKM99_04250	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FKM99_04255	COG5001	Diguanylate cyclase
FKM99_04255	COG5002	protein histidine kinase activity
FKM99_04255	COG3447	MASE1 domain protein
FKM99_04260	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FKM99_04265	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FKM99_04270	COG1984	allophanate hydrolase subunit 2
FKM99_04280	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FKM99_04285	COG4181	ATPase activity
FKM99_04295	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FKM99_04300	COG3300	MHYT domain
FKM99_04300	COG5001	Diguanylate cyclase
FKM99_04310	COG0484	heat shock protein binding
FKM99_04335	COG4533	DNA binding
FKM99_04345	COG2050	protein possibly involved in aromatic compounds catabolism
FKM99_04360	COG2067	long-chain fatty acid transport protein
FKM99_04365	COG2267	carboxylic ester hydrolase activity
FKM99_04380	COG0861	Integral membrane protein TerC family
FKM99_04385	COG0737	Belongs to the 5'-nucleotidase family
FKM99_04390	COG3593	DNA synthesis involved in DNA repair
FKM99_04400	COG0583	DNA-binding transcription factor activity
FKM99_04405	COG2116	formate transmembrane transporter activity
FKM99_04410	COG2353	YceI-like domain
FKM99_04415	COG3038	cytochrome b561
FKM99_04430	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FKM99_04435	COG0513	Belongs to the DEAD box helicase family
FKM99_04440	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FKM99_04450	COG0840	transmembrane signaling receptor activity
FKM99_04460	COG0546	phosphoglycolate phosphatase activity
FKM99_04470	COG0784	Response regulator, receiver
FKM99_04470	COG3437	response regulator, receiver
FKM99_04490	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKM99_04495	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FKM99_04500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FKM99_04515	COG2207	Transcriptional regulator
FKM99_04520	COG1979	alcohol dehydrogenase
FKM99_04540	COG1840	ABC-type Fe3 transport system, periplasmic component
FKM99_04545	COG2271	Major facilitator Superfamily
FKM99_04550	COG0469	pyruvate kinase activity
FKM99_04555	COG1126	abc transporter atp-binding protein
FKM99_04560	COG0765	amino acid transport
FKM99_04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKM99_04570	COG0765	amino acid transport
FKM99_04575	COG2203	Gaf domain
FKM99_04575	COG2200	EAL domain
FKM99_04575	COG2199	diguanylate cyclase activity
FKM99_04595	COG1609	Transcriptional regulator
FKM99_04600	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FKM99_04600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FKM99_04605	COG1105	Belongs to the carbohydrate kinase PfkB family
FKM99_04610	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FKM99_04610	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FKM99_04610	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FKM99_04650	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FKM99_04655	COG0509	glycine decarboxylation via glycine cleavage system
FKM99_04660	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FKM99_04660	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FKM99_04665	COG0210	DNA helicase
FKM99_04720	COG1078	dGTPase activity
FKM99_04750	COG4584	PFAM Integrase catalytic
FKM99_04755	COG1484	DNA-dependent DNA replication
FKM99_04790	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FKM99_04795	COG0583	DNA-binding transcription factor activity
FKM99_04850	COG0242	peptide deformylase activity
FKM99_04880	COG2239	Acts as a magnesium transporter
FKM99_04900	COG0346	lactoylglutathione lyase activity
FKM99_04905	COG1902	pentaerythritol trinitrate reductase activity
FKM99_04930	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FKM99_04940	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FKM99_04940	COG0069	glutamate synthase activity
FKM99_04950	COG4565	transcriptional regulatory protein
FKM99_04955	COG3290	protein histidine kinase activity
FKM99_04960	COG0471	metal ion transport
FKM99_04990	COG2076	Multidrug Resistance protein
FKM99_05005	COG0671	phosphoesterase, PA-phosphatase related
FKM99_05020	COG2962	Rard protein
FKM99_05040	COG0784	Response regulator, receiver
FKM99_05040	COG0835	chemotaxis
FKM99_05065	COG2197	response regulator
FKM99_05075	COG3706	GGDEF domain
FKM99_05080	COG2197	response regulator
FKM99_05085	COG5001	Diguanylate cyclase
FKM99_05085	COG3300	MHYT domain
FKM99_05100	COG0583	DNA-binding transcription factor activity
FKM99_05105	COG0583	DNA-binding transcription factor activity
FKM99_05165	COG4964	Belongs to the GSP D family
FKM99_05190	COG2207	Transcriptional regulator
FKM99_05200	COG4934	collagen metabolic process
FKM99_05210	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FKM99_05230	COG0456	acetyltransferase
FKM99_05230	COG1214	PFAM Peptidase M22, glycoprotease
FKM99_05240	COG3069	C4-dicarboxylate transmembrane transporter activity
FKM99_05245	COG1704	LemA family
FKM99_05250	COG0501	Belongs to the peptidase M48B family
FKM99_05280	COG0641	radical SAM
FKM99_05300	COG3111	PFAM Bacterial OB fold (BOF) protein
FKM99_05305	COG1597	lipid kinase activity
FKM99_05310	COG0583	DNA-binding transcription factor activity
FKM99_05315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKM99_05345	COG0714	Associated with various cellular activities
FKM99_05350	COG0641	radical SAM
FKM99_05355	COG3119	arylsulfatase activity
FKM99_05370	COG3119	arylsulfatase activity
FKM99_05375	COG3119	arylsulfatase activity
FKM99_05380	COG0745	RESPONSE REGULATOR receiver
FKM99_05395	COG2205	protein histidine kinase activity
FKM99_05395	COG0784	Response regulator, receiver
FKM99_05395	COG2198	Histidine kinase
FKM99_05400	COG1879	ABC-type sugar transport system periplasmic component
FKM99_05405	COG1803	Methylglyoxal synthase
FKM99_05410	COG0210	DNA helicase
FKM99_05415	COG1289	transmembrane transporter activity
FKM99_05450	COG4771	TonB-dependent receptor
FKM99_05450	COG1629	transport
FKM99_05465	COG0789	Transcriptional regulator
FKM99_05470	COG4604	ABC transporter, ATP-binding protein
FKM99_05475	COG4605	iron ion homeostasis
FKM99_05480	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FKM99_05485	COG4607	ABC-type enterochelin transport system periplasmic component
FKM99_05495	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FKM99_05510	COG1609	Transcriptional regulator
FKM99_05515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKM99_05520	COG1879	ABC-type sugar transport system periplasmic component
FKM99_05525	COG1172	Belongs to the binding-protein-dependent transport system permease family
FKM99_05530	COG1129	ABC transporter
FKM99_05535	COG1869	D-ribose catabolic process
FKM99_05540	COG5001	Diguanylate cyclase
FKM99_05545	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FKM99_05605	COG2205	protein histidine kinase activity
FKM99_05605	COG0784	Response regulator, receiver
FKM99_05625	COG3300	MHYT domain
FKM99_05625	COG5001	Diguanylate cyclase
FKM99_05635	COG0330	HflC and HflK could
FKM99_05650	COG4175	Glycine betaine
FKM99_05650	COG0517	IMP dehydrogenase activity
FKM99_05655	COG4176	ABC-type proline glycine betaine transport system permease component
FKM99_05670	COG1012	belongs to the aldehyde dehydrogenase family
FKM99_05675	COG1309	transcriptional regulator
FKM99_05680	COG3706	GGDEF domain
FKM99_05690	COG1028	Short-chain dehydrogenase reductase Sdr
FKM99_05705	COG1024	Enoyl-CoA hydratase
FKM99_05710	COG1960	acyl-CoA dehydrogenase activity
FKM99_05720	COG0183	Belongs to the thiolase family
FKM99_05730	COG1960	acyl-CoA dehydrogenase activity
FKM99_05735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FKM99_05755	COG3850	Histidine kinase
FKM99_05755	COG4999	Histidine kinase
FKM99_05755	COG3437	response regulator, receiver
FKM99_05755	COG2205	protein histidine kinase activity
FKM99_05770	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FKM99_05770	COG3264	Mechanosensitive ion channel
FKM99_05780	COG0110	maltose O-acetyltransferase activity
FKM99_05785	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKM99_05790	COG1271	oxidase subunit
FKM99_05795	COG1294	oxidase, subunit
FKM99_05805	COG0384	phenazine biosynthesis protein PhzF
FKM99_05810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FKM99_05815	COG0789	Transcriptional regulator
FKM99_05825	COG3474	cytochrome
FKM99_05895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FKM99_05900	COG0516	GMP reductase activity
FKM99_05905	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FKM99_05905	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FKM99_05920	COG4989	oxidoreductase activity
FKM99_05935	COG0038	chloride channel
FKM99_05945	COG1914	H( )-stimulated, divalent metal cation uptake system
FKM99_05950	COG0302	gtp cyclohydrolase
FKM99_05960	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FKM99_05980	COG2897	thiosulfate sulfurtransferase activity
FKM99_06010	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FKM99_06015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FKM99_06020	COG0840	transmembrane signaling receptor activity
FKM99_06030	COG2814	Major facilitator Superfamily
FKM99_06035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FKM99_06050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FKM99_06060	COG0840	transmembrane signaling receptor activity
FKM99_06080	COG2195	Cleaves the N-terminal amino acid of tripeptides
FKM99_06095	COG2197	response regulator
FKM99_06100	COG3850	Histidine kinase
FKM99_06105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FKM99_06115	COG0243	molybdopterin cofactor binding
FKM99_06125	COG3005	denitrification pathway
FKM99_06145	COG0183	Belongs to the thiolase family
FKM99_06155	COG1280	lysine exporter protein (LysE YggA)
FKM99_06165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FKM99_06170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FKM99_06200	COG1522	sequence-specific DNA binding
FKM99_06220	COG1566	PFAM secretion protein HlyD family protein
FKM99_06230	COG2205	protein histidine kinase activity
FKM99_06230	COG0784	Response regulator, receiver
FKM99_06235	COG1879	ABC-type sugar transport system periplasmic component
FKM99_06240	COG2827	Endonuclease containing a URI domain
FKM99_06245	COG3132	Protein of unknown function, DUF480
FKM99_06260	COG2926	Belongs to the UPF0265 family
FKM99_06265	COG0534	Mate efflux family protein
FKM99_06270	COG0673	inositol 2-dehydrogenase activity
FKM99_06275	COG0784	Response regulator, receiver
FKM99_06275	COG5002	protein histidine kinase activity
FKM99_06275	COG2205	protein histidine kinase activity
FKM99_06305	COG1522	sequence-specific DNA binding
FKM99_06315	COG0531	amino acid
FKM99_06330	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FKM99_06335	COG2239	Acts as a magnesium transporter
FKM99_06345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FKM99_06350	COG0402	S-adenosylhomocysteine deaminase activity
FKM99_06360	COG1418	mRNA catabolic process
FKM99_06375	COG2814	Major facilitator Superfamily
FKM99_06385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FKM99_06405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FKM99_06425	COG4221	oxidoreductase activity
FKM99_06430	COG0745	RESPONSE REGULATOR receiver
FKM99_06435	COG2205	protein histidine kinase activity
FKM99_06445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FKM99_06450	COG2194	sulfuric ester hydrolase activity
FKM99_06455	COG0673	inositol 2-dehydrogenase activity
FKM99_06480	COG1846	Transcriptional regulator
FKM99_06490	COG4667	esterase of the alpha-beta hydrolase superfamily
FKM99_06495	COG1741	Belongs to the pirin family
FKM99_06500	COG1278	Cold shock
FKM99_06520	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FKM99_06525	COG0678	peroxiredoxin activity
FKM99_06525	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FKM99_06540	COG1686	Belongs to the peptidase S11 family
FKM99_06555	COG0625	glutathione transferase activity
FKM99_06565	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FKM99_06585	COG1028	Short-chain dehydrogenase reductase Sdr
FKM99_06605	COG3746	phosphate-selective porin O and P
FKM99_06625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FKM99_06625	COG2207	Transcriptional regulator
FKM99_06630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKM99_06660	COG0513	Belongs to the DEAD box helicase family
FKM99_06670	COG0583	DNA-binding transcription factor activity
FKM99_06685	COG1902	pentaerythritol trinitrate reductase activity
FKM99_06700	COG1028	Short-chain dehydrogenase reductase Sdr
FKM99_06715	COG3122	Protein conserved in bacteria
FKM99_06730	COG0583	DNA-binding transcription factor activity
FKM99_06740	COG0252	asparaginase activity
FKM99_06745	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FKM99_06750	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FKM99_06750	COG0574	Belongs to the PEP-utilizing enzyme family
FKM99_06770	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FKM99_06775	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FKM99_06790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKM99_06810	COG3706	GGDEF domain
FKM99_06830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FKM99_06860	COG3842	ATPase activity
FKM99_06915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKM99_06960	COG0583	DNA-binding transcription factor activity
FKM99_06970	COG4948	Mandelate Racemase Muconate Lactonizing
FKM99_06980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FKM99_07005	COG1342	Belongs to the UPF0251 family
FKM99_07015	COG3015	lipoprotein NlpE involved in copper resistance
FKM99_07025	COG3713	MltA-interacting MipA family protein
FKM99_07040	COG0583	DNA-binding transcription factor activity
FKM99_07070	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FKM99_07080	COG1335	isochorismatase
FKM99_07090	COG0753	catalase activity
FKM99_07100	COG1349	DNA-binding transcription factor activity
FKM99_07105	COG0346	lactoylglutathione lyase activity
FKM99_07125	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FKM99_07130	COG3537	Alpha-1,2-mannosidase
FKM99_07135	COG3537	Alpha-1,2-mannosidase
FKM99_07145	COG3537	Alpha-1,2-mannosidase
FKM99_07155	COG0737	Belongs to the 5'-nucleotidase family
FKM99_07165	COG1309	transcriptional regulator
FKM99_07185	COG1280	lysine exporter protein (LysE YggA)
FKM99_07200	COG0459	protein refolding
FKM99_07205	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FKM99_07215	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FKM99_07245	COG1304	FMN binding
FKM99_07265	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FKM99_07270	COG1256	bacterial-type flagellum assembly
FKM99_07270	COG4786	Flagellar basal body rod
FKM99_07280	COG1706	bacterial-type flagellum-dependent cell motility
FKM99_07285	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FKM99_07290	COG4786	Flagellar basal body rod
FKM99_07295	COG4787	bacterial-type flagellum-dependent cell motility
FKM99_07300	COG1749	Flagellar hook protein flgE
FKM99_07305	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FKM99_07310	COG1558	bacterial-type flagellum-dependent cell motility
FKM99_07315	COG1815	bacterial-type flagellum-dependent cell motility
FKM99_07335	COG0741	lytic transglycosylase activity
FKM99_07340	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FKM99_07360	COG1760	l-serine dehydratase
FKM99_07385	COG0583	DNA-binding transcription factor activity
FKM99_07400	COG2866	Carboxypeptidase
FKM99_07405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKM99_07415	COG2990	Protein conserved in bacteria
FKM99_07440	COG3842	ATPase activity
FKM99_07450	COG1840	ABC-type Fe3 transport system, periplasmic component
FKM99_07455	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FKM99_07465	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FKM99_07470	COG1609	Transcriptional regulator
FKM99_07500	COG3240	lipase activity
FKM99_07510	COG0577	efflux transmembrane transporter activity
FKM99_07510	COG1136	(ABC) transporter
FKM99_07515	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKM99_07520	COG2067	long-chain fatty acid transport protein
FKM99_07530	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FKM99_07545	COG1011	Hydrolase
FKM99_07585	COG0110	maltose O-acetyltransferase activity
FKM99_07590	COG1765	OsmC-like protein
FKM99_07600	COG1765	OsmC-like protein
FKM99_07605	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKM99_07605	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKM99_07620	COG3046	protein related to deoxyribodipyrimidine photolyase
FKM99_07630	COG3706	GGDEF domain
FKM99_07645	COG0840	transmembrane signaling receptor activity
FKM99_07650	COG3706	GGDEF domain
FKM99_07655	COG3145	DNA-N1-methyladenine dioxygenase activity
FKM99_07665	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FKM99_07685	COG3033	Beta-eliminating lyase
FKM99_07695	COG0579	oxidoreductase
FKM99_07725	COG3706	GGDEF domain
FKM99_07770	COG0583	DNA-binding transcription factor activity
FKM99_07780	COG0189	ligase activity
FKM99_07785	COG4067	protein conserved in archaea
FKM99_07785	COG0189	ligase activity
FKM99_07795	COG1166	arginine decarboxylase activity
FKM99_07800	COG0010	Belongs to the arginase family
FKM99_07805	COG2814	Major facilitator Superfamily
FKM99_07810	COG1770	oligopeptidase
FKM99_07825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FKM99_07830	COG1121	(ABC) transporter
FKM99_07835	COG0803	Belongs to the bacterial solute-binding protein 9 family
FKM99_07875	COG0848	biopolymer transport protein
FKM99_07880	COG0811	peptide transport
FKM99_07885	COG0811	peptide transport
FKM99_07905	COG0745	RESPONSE REGULATOR receiver
FKM99_07915	COG0584	glycerophosphoryl diester phosphodiesterase
FKM99_07925	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKM99_07985	COG1901	pseudouridine methyltransferase
FKM99_07990	COG0312	modulator of DNA gyrase
FKM99_07995	COG0312	modulator of DNA gyrase
FKM99_08005	COG0351	phosphomethylpyrimidine kinase
FKM99_08010	COG1116	anion transmembrane transporter activity
FKM99_08015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FKM99_08020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FKM99_08025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FKM99_08030	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
FKM99_08035	COG0352	thiamine-phosphate diphosphorylase activity
FKM99_08045	COG0243	molybdopterin cofactor binding
FKM99_08050	COG3005	denitrification pathway
FKM99_08060	COG1028	Short-chain dehydrogenase reductase Sdr
FKM99_08075	COG0456	acetyltransferase
FKM99_08075	COG0454	-acetyltransferase
FKM99_08095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKM99_08100	COG1929	Belongs to the glycerate kinase type-1 family
FKM99_08105	COG2610	gluconate transmembrane transporter activity
FKM99_08110	COG3835	regulator
FKM99_08135	COG0546	phosphoglycolate phosphatase activity
FKM99_08150	COG0583	DNA-binding transcription factor activity
FKM99_08160	COG0583	DNA-binding transcription factor activity
FKM99_08170	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FKM99_08175	COG3408	Glycogen debranching enzyme
FKM99_08175	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
FKM99_08205	COG3047	cAMP biosynthetic process
FKM99_08210	COG1357	PFAM Pentapeptide repeats (8 copies)
FKM99_08240	COG2375	cellular response to nickel ion
FKM99_08245	COG0823	Involved in the tonB-independent uptake of proteins
FKM99_08250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FKM99_08270	COG0800	Aldolase
FKM99_08275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKM99_08290	COG1917	Cupin 2, conserved barrel domain protein
FKM99_08300	COG1028	Short-chain dehydrogenase reductase Sdr
FKM99_08305	COG1414	Transcriptional regulator
FKM99_08320	COG0583	DNA-binding transcription factor activity
FKM99_08325	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FKM99_08330	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FKM99_08345	COG2199	diguanylate cyclase activity
FKM99_08355	COG0561	phosphatase activity
FKM99_08360	COG0583	DNA-binding transcription factor activity
FKM99_08375	COG0564	pseudouridine synthase activity
FKM99_08380	COG0534	Mate efflux family protein
FKM99_08390	COG5001	Diguanylate cyclase
FKM99_08400	COG3123	guanosine phosphorylase activity
FKM99_08440	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FKM99_08450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FKM99_08455	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
FKM99_08470	COG2259	Doxx family
FKM99_08475	COG1741	Belongs to the pirin family
FKM99_08495	COG0363	glucosamine-6-phosphate deaminase activity
FKM99_08510	COG0786	glutamate:sodium symporter activity
FKM99_08515	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKM99_08520	COG1131	(ABC) transporter
FKM99_08530	COG0786	glutamate:sodium symporter activity
FKM99_08565	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FKM99_08575	COG3279	Response regulator of the LytR AlgR family
FKM99_08580	COG3275	phosphorelay sensor kinase activity
FKM99_08600	COG1136	(ABC) transporter
FKM99_08615	COG0772	Belongs to the SEDS family
FKM99_08620	COG0217	transcriptional regulatory protein
FKM99_08645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FKM99_08645	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
FKM99_08655	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FKM99_08660	COG0592	DNA-directed DNA polymerase activity
FKM99_08665	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FKM99_08670	COG0187	DNA topoisomerase II activity
FKM99_08690	COG0071	Belongs to the small heat shock protein (HSP20) family
FKM99_08695	COG3977	Valine--pyruvate aminotransferase
FKM99_08700	COG0366	Alpha amylase catalytic
FKM99_08705	COG0751	glycine-tRNA ligase activity
FKM99_08710	COG0752	glycyl-tRNA synthetase alpha subunit
FKM99_08715	COG2119	membrane
FKM99_08725	COG0425	Belongs to the sulfur carrier protein TusA family
FKM99_08740	COG0604	alcohol dehydrogenase
FKM99_08745	COG0183	Belongs to the thiolase family
FKM99_08750	COG1024	Enoyl-CoA hydratase
FKM99_08750	COG1250	3-hydroxyacyl-CoA dehydrogenase
FKM99_08755	COG1739	Uncharacterized protein family UPF0029
FKM99_08760	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FKM99_08805	COG0583	DNA-binding transcription factor activity
FKM99_08810	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FKM99_08815	COG2960	long-chain fatty acid transporting porin activity
FKM99_08825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKM99_08830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKM99_08885	COG4172	Belongs to the ABC transporter superfamily
FKM99_08890	COG0747	negative chemotaxis
FKM99_08900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FKM99_08940	COG1609	Transcriptional regulator
FKM99_08945	COG0583	DNA-binding transcription factor activity
FKM99_08955	COG2076	Multidrug Resistance protein
FKM99_08960	COG0129	dihydroxy-acid dehydratase activity
FKM99_08965	COG3265	gluconokinase activity
FKM99_08970	COG2610	gluconate transmembrane transporter activity
FKM99_08975	COG0800	Aldolase
FKM99_08980	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FKM99_08985	COG0583	DNA-binding transcription factor activity
FKM99_08990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKM99_08995	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FKM99_09005	COG0339	signal peptide processing
FKM99_09010	COG1522	sequence-specific DNA binding
FKM99_09015	COG5002	protein histidine kinase activity
FKM99_09015	COG5001	Diguanylate cyclase
FKM99_09020	COG0742	ribosomal rna small subunit methyltransferase
FKM99_09030	COG0697	spore germination
FKM99_09035	COG0589	response to stress
FKM99_09040	COG1528	Iron-storage protein
FKM99_09050	COG2081	HI0933 family
FKM99_09085	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FKM99_09090	COG0732	type I restriction modification DNA specificity domain
FKM99_09095	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FKM99_09110	COG2823	Periplasmic or secreted lipoprotein
FKM99_09160	COG0628	permease
FKM99_09175	COG1322	Protein conserved in bacteria
FKM99_09180	COG2226	methyltransferase
FKM99_09185	COG3165	ubiquinone biosynthetic process from chorismate
FKM99_09190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FKM99_09195	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FKM99_09205	COG0805	protein transport
FKM99_09215	COG0084	hydrolase, TatD family'
FKM99_09240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FKM99_09240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FKM99_09250	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FKM99_09285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FKM99_09290	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FKM99_09300	COG2204	response regulator
FKM99_09305	COG3852	Histidine kinase
FKM99_09315	COG0174	glutamine synthetase
FKM99_09335	COG1295	ribonuclease BN
FKM99_09340	COG1490	D-aminoacyl-tRNA deacylase activity
FKM99_09345	COG0456	acetyltransferase
FKM99_09355	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FKM99_09360	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FKM99_09365	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FKM99_09370	COG3031	protein transport across the cell outer membrane
FKM99_09380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FKM99_09385	COG1459	type II secretion system
FKM99_09390	COG2165	general secretion pathway protein
FKM99_09395	COG2165	general secretion pathway protein
FKM99_09400	COG2165	general secretion pathway protein
FKM99_09405	COG4795	General secretion pathway protein
FKM99_09410	COG3156	type II secretion system protein K
FKM99_09415	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FKM99_09420	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
FKM99_09430	COG1218	3'(2'),5'-bisphosphate nucleotidase
FKM99_09435	COG0494	nUDIX hydrolase
FKM99_09440	COG0316	Belongs to the HesB IscA family
FKM99_09440	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FKM99_09445	COG1040	competence protein
FKM99_09450	COG0596	Alpha beta hydrolase
FKM99_09460	COG2183	response to ionizing radiation
FKM99_09470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FKM99_09480	COG0745	RESPONSE REGULATOR receiver
FKM99_09485	COG2205	protein histidine kinase activity
FKM99_09490	COG2233	PERMEase
FKM99_09500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FKM99_09505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKM99_09510	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FKM99_09515	COG1758	RNA polymerase activity
FKM99_09520	COG0194	GDP metabolic process
FKM99_09535	COG0848	biopolymer transport protein
FKM99_09540	COG0811	peptide transport
FKM99_09565	COG4174	ABC transporter (Permease)
FKM99_09570	COG4239	(ABC) transporter, permease
FKM99_09575	COG0747	negative chemotaxis
FKM99_09580	COG0444	Belongs to the ABC transporter superfamily
FKM99_09585	COG4608	Belongs to the ABC transporter superfamily
FKM99_09595	COG1561	YicC-like family, N-terminal region
FKM99_09600	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FKM99_09605	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FKM99_09610	COG1560	Kdo2-lipid A biosynthetic process
FKM99_09615	COG1309	transcriptional regulator
FKM99_09620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FKM99_09635	COG2003	Belongs to the UPF0758 family
FKM99_09640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FKM99_09655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FKM99_09660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FKM99_09675	COG0463	Glycosyl transferase, family 2
FKM99_09680	COG0859	PFAM glycosyl transferase family 9
FKM99_09685	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FKM99_09690	COG3642	lipopolysaccharide core region biosynthetic process
FKM99_09700	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FKM99_09740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FKM99_09745	COG1519	Transferase
FKM99_09750	COG0859	PFAM glycosyl transferase family 9
FKM99_09760	COG1560	Kdo2-lipid A biosynthetic process
FKM99_09770	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FKM99_09815	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FKM99_09820	COG0438	transferase activity, transferring glycosyl groups
FKM99_09840	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FKM99_09845	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FKM99_09850	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FKM99_09870	COG1215	transferase activity, transferring glycosyl groups
FKM99_09900	COG0438	transferase activity, transferring glycosyl groups
FKM99_09920	COG0149	triose-phosphate isomerase activity
FKM99_09945	COG1494	fructose-1,6-bisphosphatase
FKM99_09955	COG3074	FtsZ-dependent cytokinesis
FKM99_09960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FKM99_09965	COG1575	Belongs to the MenA family. Type 1 subfamily
FKM99_09970	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FKM99_09975	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FKM99_09985	COG1609	Transcriptional regulator
FKM99_09990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FKM99_10000	COG0254	rRNA binding
FKM99_10010	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FKM99_10015	COG0088	Forms part of the polypeptide exit tunnel
FKM99_10025	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FKM99_10030	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FKM99_10035	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FKM99_10040	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FKM99_10050	COG0255	Belongs to the universal ribosomal protein uL29 family
FKM99_10055	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FKM99_10060	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FKM99_10065	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FKM99_10070	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FKM99_10075	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FKM99_10080	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FKM99_10085	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FKM99_10100	COG1841	ribosomal large subunit assembly
FKM99_10105	COG0200	Binds to the 23S rRNA
FKM99_10110	COG0201	protein transport
FKM99_10120	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FKM99_10125	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FKM99_10135	COG0202	RNA polymerase activity
FKM99_10140	COG0203	ribosomal protein L17
FKM99_10150	COG0545	Peptidyl-prolyl cis-trans isomerase
FKM99_10160	COG2153	protein acetylation
FKM99_10165	COG0513	Belongs to the DEAD box helicase family
FKM99_10175	COG0737	Belongs to the 5'-nucleotidase family
FKM99_10180	COG1648	precorrin-2 dehydrogenase activity
FKM99_10180	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FKM99_10185	COG0175	sulfate reduction
FKM99_10190	COG2895	sulfate adenylyltransferase (ATP) activity
FKM99_10200	COG3273	potassium ion transport
FKM99_10200	COG0471	metal ion transport
FKM99_10205	COG0529	Catalyzes the synthesis of activated sulfate
FKM99_10225	COG4181	ATPase activity
FKM99_10240	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FKM99_10250	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKM99_10255	COG0729	surface antigen
FKM99_10260	COG2911	Protein conserved in bacteria
FKM99_10265	COG2105	PFAM AIG2 family protein
FKM99_10275	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FKM99_10280	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FKM99_10290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FKM99_10295	COG0163	prenyltransferase activity
FKM99_10300	COG4143	(ABC) transporter
FKM99_10305	COG1178	ABC-type Fe3 transport system permease component
FKM99_10310	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
FKM99_10345	COG0039	L-malate dehydrogenase activity
FKM99_10355	COG0142	geranyltranstransferase activity
FKM99_10360	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FKM99_10370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FKM99_10375	COG2966	Psort location CytoplasmicMembrane, score
FKM99_10390	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FKM99_10395	COG2967	ApaG domain
FKM99_10400	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FKM99_10405	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FKM99_10410	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FKM99_10415	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FKM99_10420	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FKM99_10430	COG0066	3-isopropylmalate dehydratase activity
FKM99_10435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FKM99_10440	COG0473	3-isopropylmalate dehydrogenase activity
FKM99_10445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FKM99_10470	COG0583	DNA-binding transcription factor activity
FKM99_10475	COG1022	Amp-dependent synthetase and ligase
FKM99_10480	COG0028	Belongs to the TPP enzyme family
FKM99_10485	COG0440	acetolactate synthase activity
FKM99_10490	COG3706	GGDEF domain
FKM99_10500	COG0469	pyruvate kinase activity
FKM99_10510	COG1349	DNA-binding transcription factor activity
FKM99_10515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FKM99_10530	COG5002	protein histidine kinase activity
FKM99_10540	COG2376	Dihydroxyacetone kinase
FKM99_10545	COG1461	Dihydroxyacetone kinase
FKM99_10560	COG3722	fumarate hydratase activity
FKM99_10570	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FKM99_10570	COG2213	PTS system mannitol-specific
FKM99_10605	COG1464	Belongs to the NlpA lipoprotein family
FKM99_10650	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FKM99_10675	COG0732	type I restriction modification DNA specificity domain
FKM99_10720	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FKM99_10730	COG3550	peptidyl-serine autophosphorylation
FKM99_10745	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FKM99_10750	COG0358	DNA primase activity
FKM99_10755	COG1610	YqeY-like protein
FKM99_10760	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FKM99_10765	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FKM99_10770	COG0596	Alpha beta hydrolase
FKM99_10775	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FKM99_10780	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FKM99_10785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FKM99_10790	COG1968	undecaprenyl-diphosphatase activity
FKM99_10795	COG0617	tRNA 3'-terminal CCA addition
FKM99_10800	COG3267	Type II secretory pathway component ExeA
FKM99_10800	COG3409	Peptidoglycan-binding domain 1 protein
FKM99_10810	COG4991	sh3 domain protein
FKM99_10815	COG0306	phosphate transporter
FKM99_10820	COG1392	Phosphate transport regulator
FKM99_10825	COG3025	triphosphatase activity
FKM99_10840	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FKM99_10845	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FKM99_10845	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FKM99_10850	COG1538	Outer membrane efflux protein
FKM99_10855	COG0494	nUDIX hydrolase
FKM99_10860	COG3151	Protein conserved in bacteria
FKM99_10870	COG3150	esterase
FKM99_10875	COG0187	DNA topoisomerase II activity
FKM99_10880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FKM99_10885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FKM99_10895	COG3105	Protein conserved in bacteria
FKM99_10905	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FKM99_10915	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FKM99_10920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FKM99_10925	COG0723	plastoquinol--plastocyanin reductase activity
FKM99_10930	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FKM99_10935	COG2857	Cytochrome c1
FKM99_10940	COG0625	glutathione transferase activity
FKM99_10945	COG2969	positive regulation of protein catabolic process
FKM99_10950	COG2823	Periplasmic or secreted lipoprotein
FKM99_10955	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FKM99_10960	COG0792	nuclease activity
FKM99_10970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FKM99_10985	COG0275	rRNA processing
FKM99_10990	COG3116	cell division
FKM99_10995	COG0768	penicillin binding
FKM99_11000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FKM99_11005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FKM99_11010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FKM99_11015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FKM99_11020	COG0772	Belongs to the SEDS family
FKM99_11025	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FKM99_11030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FKM99_11035	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FKM99_11040	COG0849	cell division
FKM99_11045	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FKM99_11050	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FKM99_11060	COG0653	protein targeting
FKM99_11065	COG0494	nUDIX hydrolase
FKM99_11070	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FKM99_11075	COG0505	Belongs to the CarA family
FKM99_11080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FKM99_11095	COG0730	response to heat
FKM99_11110	COG0583	DNA-binding transcription factor activity
FKM99_11115	COG2860	membrane
FKM99_11120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FKM99_11130	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FKM99_11140	COG0493	'glutamate synthase
FKM99_11145	COG0069	glutamate synthase activity
FKM99_11145	COG0067	glutamate synthase
FKM99_11145	COG0070	glutamate synthase
FKM99_11155	COG0069	glutamate synthase activity
FKM99_11155	COG0067	glutamate synthase
FKM99_11155	COG0070	glutamate synthase
FKM99_11160	COG1242	4 iron, 4 sulfur cluster binding
FKM99_11165	COG4251	negative regulation of phosphorylation
FKM99_11165	COG2203	Gaf domain
FKM99_11165	COG3706	GGDEF domain
FKM99_11165	COG5001	Diguanylate cyclase
FKM99_11170	COG5002	protein histidine kinase activity
FKM99_11170	COG2198	Histidine kinase
FKM99_11170	COG0784	Response regulator, receiver
FKM99_11180	COG0745	RESPONSE REGULATOR receiver
FKM99_11195	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FKM99_11210	COG0083	homoserine kinase activity
FKM99_11215	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FKM99_11220	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FKM99_11225	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FKM99_11235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FKM99_11250	COG1115	amino acid carrier protein
FKM99_11255	COG3022	response to hydroperoxide
FKM99_11260	COG0513	Belongs to the DEAD box helicase family
FKM99_11265	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FKM99_11275	COG0716	FMN binding
FKM99_11285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FKM99_11290	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FKM99_11300	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FKM99_11315	COG0667	Aldo Keto reductase
FKM99_11325	COG3066	DNA modification
FKM99_11335	COG0494	nUDIX hydrolase
FKM99_11345	COG0730	response to heat
FKM99_11350	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FKM99_11355	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FKM99_11365	COG1283	sodium-dependent phosphate transmembrane transporter activity
FKM99_11370	COG0583	DNA-binding transcription factor activity
FKM99_11380	COG0640	Transcriptional regulator
FKM99_11390	COG0268	Binds directly to 16S ribosomal RNA
FKM99_11395	COG0728	peptidoglycan biosynthetic process
FKM99_11400	COG0196	riboflavin kinase activity
FKM99_11405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FKM99_11410	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FKM99_11415	COG1047	Peptidyl-prolyl cis-trans
FKM99_11420	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FKM99_11425	COG3279	Response regulator of the LytR AlgR family
FKM99_11430	COG3275	phosphorelay sensor kinase activity
FKM99_11435	COG1966	Carbon starvation protein
FKM99_11450	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FKM99_11455	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FKM99_11460	COG1472	Belongs to the glycosyl hydrolase 3 family
FKM99_11465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FKM99_11470	COG0287	Prephenate dehydrogenase
FKM99_11470	COG1605	Chorismate mutase
FKM99_11475	COG0739	heme binding
FKM99_11490	COG0488	(ABC) transporter
FKM99_11500	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FKM99_11505	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FKM99_11510	COG1605	Chorismate mutase
FKM99_11510	COG0077	Prephenate dehydratase
FKM99_11515	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FKM99_11520	COG0741	lytic transglycosylase activity
FKM99_11525	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FKM99_11530	COG0564	pseudouridine synthase activity
FKM99_11540	COG0542	response to heat
FKM99_11600	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FKM99_11610	COG2974	May be involved in recombination
FKM99_11620	COG0745	RESPONSE REGULATOR receiver
FKM99_11625	COG5002	protein histidine kinase activity
FKM99_11635	COG0248	Ppx GppA phosphatase
FKM99_11640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FKM99_11650	COG0581	inorganic phosphate transmembrane transporter activity
FKM99_11655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FKM99_11660	COG0704	Plays a role in the regulation of phosphate uptake
FKM99_11670	COG3142	Participates in the control of copper homeostasis
FKM99_11680	COG0450	alkyl hydroperoxide reductase
FKM99_11685	COG0583	DNA-binding transcription factor activity
FKM99_11695	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FKM99_11705	COG0517	IMP dehydrogenase activity
FKM99_11720	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FKM99_11725	COG0343	queuine tRNA-ribosyltransferase activity
FKM99_11730	COG1862	Preprotein translocase
FKM99_11735	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FKM99_11740	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FKM99_11750	COG0483	inositol monophosphate 1-phosphatase activity
FKM99_11765	COG1104	cysteine desulfurase activity
FKM99_11770	COG0822	iron-sulfur transferase activity
FKM99_11780	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FKM99_11785	COG0443	Heat shock 70 kDa protein
FKM99_11790	COG0633	Ferredoxin
FKM99_11795	COG2975	iron-sulfur cluster assembly
FKM99_11800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FKM99_11805	COG0105	UTP biosynthetic process
FKM99_11810	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FKM99_11825	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FKM99_11830	COG0124	histidyl-tRNA synthetase
FKM99_11835	COG2976	Protein conserved in bacteria
FKM99_11840	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FKM99_11845	COG1160	GTP binding
FKM99_11860	COG1570	exodeoxyribonuclease VII activity
FKM99_11865	COG0516	GMP reductase activity
FKM99_11865	COG0517	IMP dehydrogenase activity
FKM99_11870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FKM99_11870	COG0519	Catalyzes the synthesis of GMP from XMP
FKM99_11875	COG1757	Na H antiporter
FKM99_11885	COG1584	GPR1 FUN34 yaaH family protein
FKM99_11895	COG1115	amino acid carrier protein
FKM99_11935	COG2873	o-acetylhomoserine
FKM99_11940	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FKM99_11945	COG3246	L-lysine catabolic process to acetate
FKM99_11960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FKM99_11960	COG3153	acetyltransferase
FKM99_11965	COG0583	DNA-binding transcription factor activity
FKM99_12010	COG2199	diguanylate cyclase activity
FKM99_12040	COG0732	type I restriction modification DNA specificity domain
FKM99_12100	COG0582	viral genome integration into host DNA
FKM99_12110	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FKM99_12115	COG2867	negative regulation of translational initiation
FKM99_12120	COG2914	Belongs to the UPF0125 (RnfH) family
FKM99_12125	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FKM99_12130	COG0497	DNA recombination
FKM99_12140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FKM99_12145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FKM99_12155	COG0443	Heat shock 70 kDa protein
FKM99_12160	COG0484	heat shock protein binding
FKM99_12200	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FKM99_12205	COG0590	tRNA wobble adenosine to inosine editing
FKM99_12215	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FKM99_12220	COG0047	phosphoribosylformylglycinamidine synthase activity
FKM99_12220	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FKM99_12245	COG2195	Cleaves the N-terminal amino acid of tripeptides
FKM99_12250	COG2252	PERMEase
FKM99_12255	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FKM99_12270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FKM99_12275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FKM99_12280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FKM99_12285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKM99_12285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FKM99_12305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FKM99_12310	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FKM99_12315	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FKM99_12320	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FKM99_12325	COG0142	geranyltranstransferase activity
FKM99_12330	COG1722	exodeoxyribonuclease VII activity
FKM99_12335	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FKM99_12340	COG2885	chlorophyll binding
FKM99_12345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FKM99_12345	COG0301	tRNA thio-modification
FKM99_12350	COG0583	DNA-binding transcription factor activity
FKM99_12360	COG2363	Small membrane protein
FKM99_12365	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FKM99_12375	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FKM99_12380	COG1611	Belongs to the LOG family
FKM99_12385	COG3706	GGDEF domain
FKM99_12385	COG0745	RESPONSE REGULATOR receiver
FKM99_12395	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FKM99_12395	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FKM99_12405	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
FKM99_12410	COG1464	Belongs to the NlpA lipoprotein family
FKM99_12415	COG2011	ABC-type metal ion transport system permease component
FKM99_12420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FKM99_12430	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FKM99_12440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FKM99_12440	COG1263	PTS System
FKM99_12445	COG0366	Alpha amylase catalytic
FKM99_12460	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
FKM99_12465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FKM99_12470	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FKM99_12475	COG0321	lipoyl(octanoyl) transferase activity
FKM99_12480	COG2921	Belongs to the UPF0250 family
FKM99_12485	COG1686	Belongs to the peptidase S11 family
FKM99_12490	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FKM99_12495	COG0772	Belongs to the SEDS family
FKM99_12500	COG0768	penicillin binding
FKM99_12505	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FKM99_12510	COG0799	negative regulation of ribosome biogenesis
FKM99_12515	COG1466	dna polymerase III delta subunit
FKM99_12520	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FKM99_12525	COG0495	leucyl-tRNA aminoacylation
FKM99_12530	COG2888	peptidyl-tyrosine sulfation
FKM99_12535	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FKM99_12540	COG4535	Mg2 and Co2 transporter CorC
FKM99_12545	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FKM99_12550	COG1702	phosphate starvation-inducible protein PhoH
FKM99_12555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FKM99_12565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKM99_12665	COG0012	GTP binding
FKM99_12670	COG0193	aminoacyl-tRNA hydrolase activity
FKM99_12675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FKM99_12680	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FKM99_12685	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FKM99_12690	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FKM99_12695	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FKM99_12700	COG2890	protein-(glutamine-N5) methyltransferase activity
FKM99_12705	COG3094	Invasion gene expression up-regulator, SirB
FKM99_12710	COG2912	Transglutaminase-like superfamily
FKM99_12715	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FKM99_12720	COG0737	Belongs to the 5'-nucleotidase family
FKM99_12730	COG1187	pseudouridine synthase activity
FKM99_12735	COG2840	Smr protein MutS2
FKM99_12775	COG2608	mercury ion transmembrane transporter activity
FKM99_12775	COG2217	Heavy metal translocating P-type atpase
FKM99_12790	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FKM99_12795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKM99_12855	COG0835	chemotaxis
FKM99_12855	COG0784	Response regulator, receiver
FKM99_12860	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FKM99_12865	COG1815	bacterial-type flagellum-dependent cell motility
FKM99_12870	COG1558	bacterial-type flagellum-dependent cell motility
FKM99_12875	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FKM99_12880	COG1749	Flagellar hook protein flgE
FKM99_12890	COG4787	bacterial-type flagellum-dependent cell motility
FKM99_12895	COG4786	Flagellar basal body rod
FKM99_12900	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FKM99_12905	COG1706	bacterial-type flagellum-dependent cell motility
FKM99_12910	COG1705	Flagellar rod assembly protein muramidase FlgJ
FKM99_12910	COG3951	Flagellar rod assembly protein muramidase FlgJ
FKM99_12920	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FKM99_12930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FKM99_12940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FKM99_12945	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FKM99_12955	COG2190	(PTS) system
FKM99_12960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FKM99_12965	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FKM99_12975	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FKM99_12980	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FKM99_12985	COG3115	cell septum assembly
FKM99_12990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FKM99_13015	COG0330	HflC and HflK could
FKM99_13020	COG2194	sulfuric ester hydrolase activity
FKM99_13040	COG1215	transferase activity, transferring glycosyl groups
FKM99_13045	COG1215	transferase activity, transferring glycosyl groups
FKM99_13050	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FKM99_13055	COG3118	belongs to the thioredoxin family
FKM99_13055	COG0457	Tetratricopeptide repeat
FKM99_13060	COG3118	belongs to the thioredoxin family
FKM99_13070	COG0300	oxidoreductase activity
FKM99_13075	COG1090	epimerase
FKM99_13105	COG0622	Phosphoesterase
FKM99_13125	COG3710	Transcriptional regulator
FKM99_13130	COG0326	Molecular chaperone. Has ATPase activity
FKM99_13135	COG0563	adenylate kinase activity
FKM99_13140	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FKM99_13145	COG3104	oligopeptide transport
FKM99_13150	COG0250	Participates in transcription elongation, termination and antitermination
FKM99_13155	COG0367	asparagine synthase
FKM99_13160	COG4651	solute:proton antiporter activity
FKM99_13160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FKM99_13165	COG1940	carbohydrate kinase activity
FKM99_13165	COG1846	Transcriptional regulator
FKM99_13170	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FKM99_13180	COG1263	PTS System
FKM99_13180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FKM99_13180	COG2190	(PTS) system
FKM99_13185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKM99_13190	COG0735	belongs to the Fur family
FKM99_13200	COG0716	FMN binding
FKM99_13210	COG0596	Alpha beta hydrolase
FKM99_13215	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FKM99_13220	COG0033	Phosphoglucomutase
FKM99_13230	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FKM99_13240	COG2009	succinate dehydrogenase
FKM99_13245	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FKM99_13250	COG1053	succinate dehydrogenase
FKM99_13255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FKM99_13260	COG0567	Dehydrogenase, E1 component
FKM99_13265	COG0508	dehydrogenase complex catalyzes the overall conversion of
FKM99_13270	COG0045	succinate-CoA ligase (ADP-forming) activity
FKM99_13280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FKM99_13285	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FKM99_13290	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FKM99_13295	COG2233	PERMEase
FKM99_13315	COG4783	chaperone-mediated protein folding
FKM99_13330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FKM99_13335	COG2716	regulation of RNA biosynthetic process
FKM99_13340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKM99_13360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FKM99_13365	COG1393	Belongs to the ArsC family
FKM99_13395	COG2837	iron assimilation
FKM99_13400	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FKM99_13410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FKM99_13415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FKM99_13420	COG1334	flagellar protein FlaG
FKM99_13425	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FKM99_13435	COG1516	flagellar protein fliS
FKM99_13445	COG4191	Histidine kinase
FKM99_13450	COG2204	response regulator
FKM99_13455	COG1677	Flagellar hook-basal body complex protein FliE
FKM99_13465	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FKM99_13515	COG1987	bacterial-type flagellum assembly
FKM99_13520	COG1684	flagellar biosynthetic protein fliR
FKM99_13540	COG0455	bacterial-type flagellum organization
FKM99_13555	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FKM99_13560	COG0643	Histidine kinase
FKM99_13560	COG2198	Histidine kinase
FKM99_13565	COG2201	protein-glutamate methylesterase activity
FKM99_13570	COG1192	Involved in chromosome partitioning
FKM99_13580	COG0835	chemotaxis
FKM99_13590	COG4133	protoheme IX ABC transporter activity
FKM99_13595	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FKM99_13600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FKM99_13605	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FKM99_13610	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FKM99_13615	COG1138	Cytochrome C-type biogenesis protein
FKM99_13620	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FKM99_13635	COG2853	Lipoprotein
FKM99_13645	COG2067	long-chain fatty acid transport protein
FKM99_13665	COG0183	Belongs to the thiolase family
FKM99_13670	COG1024	Enoyl-CoA hydratase
FKM99_13670	COG1250	3-hydroxyacyl-CoA dehydrogenase
FKM99_13685	COG2062	phosphohistidine phosphatase, SixA
FKM99_13690	COG2840	Smr protein MutS2
FKM99_13695	COG2890	protein-(glutamine-N5) methyltransferase activity
FKM99_13700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FKM99_13705	COG2860	membrane
FKM99_13715	COG3101	peptidyl-lysine hydroxylation
FKM99_13730	COG0431	NADPH-dependent FMN reductase
FKM99_13795	COG4387	Mu-like prophage protein GP36
FKM99_13805	COG4397	Mu-like prophage major head subunit gpT
FKM99_13815	COG4388	Caudovirus prohead serine protease
FKM99_13845	COG4383	Mu-like prophage protein gp29
FKM99_13850	COG4373	Mu-like prophage FluMu protein gp28
FKM99_13860	COG0640	Transcriptional regulator
FKM99_13885	COG5566	PFAM Mor transcription activator
FKM99_13915	COG4382	Mu-like prophage protein Gp16
FKM99_13960	COG2842	Transposition protein
FKM99_13965	COG2801	Transposase and inactivated derivatives
FKM99_13975	COG3423	Transcriptional regulator
FKM99_13980	COG2932	Transcriptional regulator
FKM99_13990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FKM99_14000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FKM99_14005	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FKM99_14015	COG0101	tRNA pseudouridine synthase activity
FKM99_14020	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FKM99_14025	COG0285	dihydrofolate synthase activity
FKM99_14030	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FKM99_14035	COG1286	toxin biosynthetic process
FKM99_14040	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FKM99_14045	COG0583	DNA-binding transcription factor activity
FKM99_14050	COG0745	RESPONSE REGULATOR receiver
FKM99_14060	COG2832	Protein of unknown function (DUF454)
FKM99_14065	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FKM99_14075	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FKM99_14080	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FKM99_14085	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FKM99_14090	COG0814	amino acid
FKM99_14095	COG0251	oxidation-reduction process
FKM99_14100	COG3681	Belongs to the UPF0597 family
FKM99_14115	COG2261	transglycosylase associated protein
FKM99_14120	COG2983	Belongs to the UPF0260 family
FKM99_14125	COG0668	transmembrane transport
FKM99_14130	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FKM99_14135	COG0346	lactoylglutathione lyase activity
FKM99_14145	COG1785	Belongs to the alkaline phosphatase family
FKM99_14165	COG2226	methyltransferase
FKM99_14180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FKM99_14185	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FKM99_14195	COG3139	Protein of unknown function (DUF1315)
FKM99_14200	COG0252	asparaginase activity
FKM99_14205	COG0616	signal peptide processing
FKM99_14210	COG0446	pyridine nucleotide-disulphide oxidoreductase
FKM99_14210	COG1902	pentaerythritol trinitrate reductase activity
FKM99_14215	COG0778	Nitroreductase
FKM99_14220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FKM99_14240	COG0123	including yeast histone deacetylase and acetoin utilization protein
FKM99_14260	COG0582	viral genome integration into host DNA
FKM99_14280	COG3083	sulfuric ester hydrolase activity
FKM99_14285	COG3082	Protein of unknown function (DUF1414)
FKM99_14290	COG3081	Nucleoid-associated protein
FKM99_14305	COG1757	Na H antiporter
FKM99_14310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FKM99_14315	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKM99_14320	COG2095	MarC family integral membrane protein
FKM99_14325	COG1012	belongs to the aldehyde dehydrogenase family
FKM99_14325	COG1454	alcohol dehydrogenase
FKM99_14345	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FKM99_14355	COG2056	Na+-H+ antiporter family
FKM99_14360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FKM99_14375	COG2885	chlorophyll binding
FKM99_14385	COG0346	lactoylglutathione lyase activity
FKM99_14390	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FKM99_14395	COG4660	Part of a membrane complex involved in electron transport
FKM99_14400	COG4659	FMN binding
FKM99_14405	COG4658	electron transport chain
FKM99_14410	COG4656	Part of a membrane complex involved in electron transport
FKM99_14415	COG2878	Part of a membrane complex involved in electron transport
FKM99_14420	COG4657	Part of a membrane complex involved in electron transport
FKM99_14435	COG0556	nucleotide-excision repair
FKM99_14440	COG2204	response regulator
FKM99_14445	COG2198	Histidine kinase
FKM99_14450	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FKM99_14455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FKM99_14460	COG0521	Mo-molybdopterin cofactor biosynthetic process
FKM99_14465	COG0315	cyclic pyranopterin monophosphate synthase activity
FKM99_14470	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FKM99_14475	COG0314	molybdopterin synthase activity
FKM99_14485	COG0601	transmembrane transport
FKM99_14490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FKM99_14495	COG0444	Belongs to the ABC transporter superfamily
FKM99_14505	COG0435	Glutathione S-transferase
FKM99_14515	COG3174	membrane
FKM99_14520	COG0857	belongs to the CobB CobQ family
FKM99_14520	COG0280	phosphate acetyltransferase
FKM99_14525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FKM99_14530	COG3092	negative regulation of chromosome organization
FKM99_14540	COG4120	Belongs to the binding-protein-dependent transport system permease family
FKM99_14545	COG1122	ATPase activity
FKM99_14550	COG0366	Alpha amylase catalytic
FKM99_14555	COG2199	diguanylate cyclase activity
FKM99_14555	COG2203	Gaf domain
FKM99_14560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FKM99_14565	COG3318	Belongs to the UPF0149 family
FKM99_14565	COG3012	SEC-C Motif Domain Protein
FKM99_14570	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FKM99_14575	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FKM99_14580	COG2186	Transcriptional regulator
FKM99_14590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKM99_14590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKM99_14595	COG0489	protein tyrosine kinase activity
FKM99_14600	COG0572	uridine kinase
FKM99_14610	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FKM99_14615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FKM99_14620	COG0659	secondary active sulfate transmembrane transporter activity
FKM99_14630	COG1530	ribonuclease E activity
FKM99_14645	COG0564	pseudouridine synthase activity
FKM99_14650	COG0424	maF-like protein
FKM99_14655	COG1399	metal-binding, possibly nucleic acid-binding protein
FKM99_14665	COG0416	fatty acid biosynthetic process
FKM99_14670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FKM99_14700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FKM99_14705	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FKM99_14715	COG0084	hydrolase, TatD family'
FKM99_14720	COG1263	PTS System
FKM99_14720	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FKM99_14740	COG0733	neurotransmitter:sodium symporter activity
FKM99_14755	COG4667	esterase of the alpha-beta hydrolase superfamily
FKM99_14760	COG0469	pyruvate kinase activity
FKM99_14765	COG1940	carbohydrate kinase activity
FKM99_14770	COG0835	chemotaxis
FKM99_14770	COG0784	Response regulator, receiver
FKM99_14775	COG0587	DNA-directed DNA polymerase activity
FKM99_14790	COG1028	Short-chain dehydrogenase reductase Sdr
FKM99_14795	COG0616	signal peptide processing
FKM99_14800	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FKM99_14805	COG0539	negative regulation of cytoplasmic translation
FKM99_14815	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FKM99_14820	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FKM99_14825	COG0284	orotidine-5'-phosphate decarboxylase activity
FKM99_14830	COG4166	transmembrane transport
FKM99_14855	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FKM99_14865	COG3008	intermembrane lipid transfer
FKM99_14865	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FKM99_14870	COG2995	paraquat-inducible protein a
FKM99_14880	COG2863	cytochrome
FKM99_14920	COG4232	protein-disulfide reductase activity
FKM99_14925	COG3118	belongs to the thioredoxin family
FKM99_14955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKM99_14965	COG1136	(ABC) transporter
FKM99_14965	COG0577	efflux transmembrane transporter activity
FKM99_14970	COG0577	efflux transmembrane transporter activity
FKM99_14970	COG1136	(ABC) transporter
FKM99_14975	COG1136	(ABC) transporter
FKM99_14975	COG0577	efflux transmembrane transporter activity
FKM99_14980	COG1335	isochorismatase
FKM99_14995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FKM99_15030	COG3850	Histidine kinase
FKM99_15030	COG5002	protein histidine kinase activity
FKM99_15035	COG0745	RESPONSE REGULATOR receiver
FKM99_15045	COG0840	transmembrane signaling receptor activity
FKM99_15050	COG1032	radical SAM domain protein
FKM99_15055	COG4251	negative regulation of phosphorylation
FKM99_15055	COG5001	Diguanylate cyclase
FKM99_15055	COG2203	Gaf domain
FKM99_15055	COG3706	GGDEF domain
FKM99_15070	COG0583	DNA-binding transcription factor activity
FKM99_15080	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FKM99_15090	COG2350	Protein conserved in bacteria
FKM99_15095	COG1607	acyl-coa hydrolase
FKM99_15100	COG2917	probably involved in intracellular septation
FKM99_15120	COG1301	dicarboxylic acid transport
FKM99_15130	COG0318	PFAM AMP-dependent synthetase and ligase
FKM99_15135	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKM99_15145	COG0159	tryptophan synthase activity
FKM99_15150	COG0133	tryptophan synthase activity
FKM99_15155	COG0135	phosphoribosylanthranilate isomerase activity
FKM99_15155	COG0134	indole-3-glycerol-phosphate synthase activity
FKM99_15160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FKM99_15165	COG0512	Glutamine amidotransferase of anthranilate synthase
FKM99_15170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FKM99_15180	COG0613	PHP domain protein
FKM99_15185	COG0009	L-threonylcarbamoyladenylate synthase
FKM99_15195	COG1187	pseudouridine synthase activity
FKM99_15205	COG3099	Belongs to the UPF0263 family
FKM99_15210	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FKM99_15220	COG0417	DNA replication proofreading
FKM99_15225	COG2197	response regulator
FKM99_15230	COG0322	excinuclease ABC activity
FKM99_15270	COG0019	diaminopimelate decarboxylase activity
FKM99_15295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FKM99_15300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FKM99_15305	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FKM99_15325	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FKM99_15335	COG0437	4 iron, 4 sulfur cluster binding
FKM99_15340	COG3301	Polysulphide reductase, NrfD
FKM99_15345	COG1138	Cytochrome C-type biogenesis protein
FKM99_15355	COG3088	subunit of a heme lyase
FKM99_15355	COG4235	cytochrome complex assembly
FKM99_15365	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FKM99_15390	COG2989	Protein conserved in bacteria
FKM99_15395	COG3108	Peptidase M15
FKM99_15400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKM99_15415	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FKM99_15440	COG1846	Transcriptional regulator
FKM99_15445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FKM99_15450	COG0840	transmembrane signaling receptor activity
FKM99_15470	COG1448	Aminotransferase
FKM99_15495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FKM99_15505	COG0017	Asparaginyl-tRNA synthetase
FKM99_15510	COG0840	transmembrane signaling receptor activity
FKM99_15515	COG0720	synthase
FKM99_15525	COG2200	EAL domain
FKM99_15530	COG1760	l-serine dehydratase
FKM99_15535	COG0814	amino acid
FKM99_15540	COG0494	nUDIX hydrolase
FKM99_15550	COG2205	protein histidine kinase activity
FKM99_15550	COG0784	Response regulator, receiver
FKM99_15555	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FKM99_15575	COG3106	COG3106 Predicted ATPase
FKM99_15580	COG3768	UPF0283 membrane protein
FKM99_15590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FKM99_15975	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FKM99_16015	COG1484	DNA-dependent DNA replication
FKM99_16020	COG4584	PFAM Integrase catalytic
FKM99_16155	COG1335	isochorismatase
FKM99_16245	COG2026	Addiction module toxin, RelE StbE family
FKM99_16305	COG2161	toxin-antitoxin pair type II binding
FKM99_16310	COG4115	mRNA cleavage
FKM99_16445	COG4584	PFAM Integrase catalytic
FKM99_16450	COG1484	DNA-dependent DNA replication
FKM99_16645	COG2161	toxin-antitoxin pair type II binding
FKM99_16650	COG4115	mRNA cleavage
FKM99_16845	COG0346	lactoylglutathione lyase activity
FKM99_16915	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FKM99_16920	COG0583	DNA-binding transcription factor activity
FKM99_16955	COG0471	metal ion transport
FKM99_16960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKM99_16960	COG4191	Histidine kinase
FKM99_16970	COG3300	MHYT domain
FKM99_16970	COG5001	Diguanylate cyclase
FKM99_16980	COG1280	lysine exporter protein (LysE YggA)
FKM99_16985	COG1328	CTP reductase activity
FKM99_16990	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FKM99_17000	COG0861	Integral membrane protein TerC family
FKM99_17010	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FKM99_17025	COG0814	amino acid
FKM99_17050	COG1132	(ABC) transporter
FKM99_17055	COG1132	(ABC) transporter
FKM99_17085	COG0443	Heat shock 70 kDa protein
FKM99_17090	COG0443	Heat shock 70 kDa protein
FKM99_17130	COG0243	molybdopterin cofactor binding
FKM99_17135	COG0437	4 iron, 4 sulfur cluster binding
FKM99_17140	COG3302	dmso reductase anchor subunit
FKM99_17155	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FKM99_17160	COG1643	Atp-dependent helicase
FKM99_17175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FKM99_17185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FKM99_17190	COG1215	transferase activity, transferring glycosyl groups
FKM99_17195	COG0438	transferase activity, transferring glycosyl groups
FKM99_17240	COG2204	response regulator
FKM99_17275	COG1793	dna ligase
FKM99_17285	COG0534	Mate efflux family protein
FKM99_17290	COG0307	riboflavin synthase, alpha
FKM99_17305	COG2201	protein-glutamate methylesterase activity
FKM99_17310	COG3706	GGDEF domain
FKM99_17320	COG0791	NLP P60 protein
FKM99_17325	COG3290	protein histidine kinase activity
FKM99_17325	COG0840	transmembrane signaling receptor activity
FKM99_17365	COG1940	carbohydrate kinase activity
FKM99_17380	COG0746	molybdenum cofactor guanylyltransferase activity
FKM99_17385	COG3842	ATPase activity
FKM99_17405	COG2204	response regulator
FKM99_17410	COG4191	Histidine kinase
FKM99_17420	COG0488	(ABC) transporter
FKM99_17425	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FKM99_17450	COG3381	protein complex oligomerization
FKM99_17460	COG0243	molybdopterin cofactor binding
FKM99_17460	COG3383	formate dehydrogenase (NAD+) activity
FKM99_17465	COG0437	4 iron, 4 sulfur cluster binding
FKM99_17505	COG0004	ammonium transporteR
FKM99_17515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FKM99_17520	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FKM99_17525	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FKM99_17530	COG1177	transmembrane transport
FKM99_17535	COG1176	ABC-type spermidine putrescine transport system, permease component I
FKM99_17540	COG3842	ATPase activity
FKM99_17560	COG0037	tRNA processing
FKM99_17570	COG0589	response to stress
FKM99_17575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKM99_17590	COG2217	Heavy metal translocating P-type atpase
FKM99_17600	COG2010	Cytochrome c
FKM99_17615	COG3278	Belongs to the heme-copper respiratory oxidase family
FKM99_17650	COG3120	sequence-specific DNA binding
FKM99_17655	COG1067	ATP-dependent peptidase activity
FKM99_17660	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FKM99_17685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FKM99_17685	COG0116	Belongs to the methyltransferase superfamily
FKM99_17700	COG0167	dihydroorotate dehydrogenase activity
FKM99_17705	COG2902	Dehydrogenase
FKM99_17715	COG0308	aminopeptidase N
FKM99_17730	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
FKM99_17735	COG1956	GAF domain-containing protein
FKM99_17740	COG1132	(ABC) transporter
FKM99_17745	COG2995	paraquat-inducible protein a
FKM99_17750	COG3008	intermembrane lipid transfer
FKM99_17760	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FKM99_17760	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
FKM99_17780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FKM99_17785	COG1666	GTP binding
FKM99_17805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKM99_17810	COG4597	amino acid ABC transporter
FKM99_17815	COG0765	amino acid transport
FKM99_17820	COG1126	abc transporter atp-binding protein
FKM99_17825	COG0670	Belongs to the BI1 family
FKM99_17835	COG2920	part of a sulfur-relay system
FKM99_17840	COG1254	Belongs to the acylphosphatase family
FKM99_17845	COG0840	transmembrane signaling receptor activity
FKM99_17850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FKM99_17890	COG3706	GGDEF domain
FKM99_17895	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FKM99_17900	COG0602	queuosine metabolic process
FKM99_17905	COG0561	phosphatase activity
FKM99_17930	COG2828	Protein conserved in bacteria
FKM99_17940	COG0372	Belongs to the citrate synthase family
FKM99_17945	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
FKM99_17975	COG0730	response to heat
FKM99_17995	COG0457	Tetratricopeptide repeat
FKM99_18060	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FKM99_18065	COG4790	Type iii secretion
FKM99_18070	COG4794	Type iii secretion
FKM99_18075	COG4791	protein targeting
FKM99_18080	COG4792	protein secretion
FKM99_18090	COG1073	alpha beta
FKM99_18095	COG1073	alpha beta
FKM99_18135	COG3177	Filamentation induced by cAMP protein fic
FKM99_18155	COG4669	(LipO)protein
FKM99_18225	COG1012	belongs to the aldehyde dehydrogenase family
FKM99_18230	COG3284	Transcriptional regulator
FKM99_18255	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FKM99_18260	COG0363	glucosamine-6-phosphate deaminase activity
FKM99_18265	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FKM99_18270	COG4565	transcriptional regulatory protein
FKM99_18275	COG3290	protein histidine kinase activity
FKM99_18290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKM99_18305	COG1858	cytochrome C peroxidase
FKM99_18320	COG0527	aspartate kinase activity
FKM99_18325	COG0662	Cupin 2, conserved barrel domain protein
FKM99_18330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FKM99_18335	COG0456	acetyltransferase
FKM99_18340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FKM99_18360	COG4176	ABC-type proline glycine betaine transport system permease component
FKM99_18365	COG2113	Glycine betaine
FKM99_18380	COG1022	Amp-dependent synthetase and ligase
FKM99_18390	COG1028	Short-chain dehydrogenase reductase Sdr
FKM99_18400	COG0745	RESPONSE REGULATOR receiver
FKM99_18405	COG0642	Histidine kinase
FKM99_18410	COG1368	sulfuric ester hydrolase activity
FKM99_18435	COG1115	amino acid carrier protein
FKM99_18445	COG1280	lysine exporter protein (LysE YggA)
FKM99_18460	COG3550	peptidyl-serine autophosphorylation
FKM99_18470	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FKM99_18475	COG1484	DNA-dependent DNA replication
FKM99_18480	COG4584	PFAM Integrase catalytic
FKM99_18535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FKM99_18540	COG0840	transmembrane signaling receptor activity
FKM99_18545	COG4580	involved in the transport of maltose and maltodextrins
FKM99_18550	COG1874	Beta-galactosidase
FKM99_18560	COG3833	ABC-type maltose transport systems, permease component
FKM99_18565	COG1175	transmembrane transport
FKM99_18570	COG2182	Extracellular solute-binding protein
FKM99_18650	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FKM99_18660	COG1560	Kdo2-lipid A biosynthetic process
FKM99_18670	COG0531	amino acid
FKM99_18685	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FKM99_18690	COG3063	Type IV pilus biogenesis stability protein PilW
FKM99_18720	COG0110	maltose O-acetyltransferase activity
FKM99_18740	COG2315	Protein conserved in bacteria
FKM99_18745	COG1846	Transcriptional regulator
FKM99_18760	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FKM99_18775	COG2200	EAL domain
FKM99_18775	COG2771	luxR family
FKM99_18785	COG1227	inorganic diphosphatase activity
FKM99_18790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FKM99_18795	COG1012	belongs to the aldehyde dehydrogenase family
FKM99_18800	COG2957	Belongs to the agmatine deiminase family
FKM99_18810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FKM99_18815	COG1012	belongs to the aldehyde dehydrogenase family
FKM99_18820	COG1396	sequence-specific DNA binding
FKM99_18820	COG1917	Cupin 2, conserved barrel domain protein
FKM99_18825	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FKM99_18835	COG0174	glutamine synthetase
FKM99_18840	COG1757	Na H antiporter
FKM99_18865	COG1280	lysine exporter protein (LysE YggA)
FKM99_18910	COG0625	glutathione transferase activity
FKM99_18920	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
FKM99_18935	COG2195	Cleaves the N-terminal amino acid of tripeptides
FKM99_18945	COG0601	transmembrane transport
FKM99_18950	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FKM99_18955	COG0444	Belongs to the ABC transporter superfamily
FKM99_18975	COG3291	Pkd domain containing protein
FKM99_18990	COG1177	transmembrane transport
FKM99_18995	COG1176	ABC-type spermidine putrescine transport system, permease component I
FKM99_19000	COG3842	ATPase activity
FKM99_19005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FKM99_19010	COG2423	ornithine cyclodeaminase activity
FKM99_19030	COG3938	Belongs to the proline racemase family
FKM99_19060	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FKM99_19065	COG1451	nucleotide metabolic process
FKM99_19070	COG3475	LICD family
FKM99_19075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FKM99_19080	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FKM99_19100	COG0583	DNA-binding transcription factor activity
FKM99_19120	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FKM99_19125	COG4139	cobalamin transport
FKM99_19130	COG2988	succinylglutamate desuccinylase activity
FKM99_19145	COG2062	phosphohistidine phosphatase, SixA
FKM99_19155	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FKM99_19160	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FKM99_19165	COG0702	epimerase
FKM99_19175	COG2925	Exonuclease
FKM99_19180	COG1380	Effector of murein hydrolase LrgA
FKM99_19185	COG1346	cytolysis
FKM99_19190	COG0295	cytidine deaminase activity
FKM99_19195	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FKM99_19200	COG0500	methyltransferase
FKM99_19210	COG0776	regulation of translation
FKM99_19225	COG0072	phenylalanine-tRNA ligase activity
FKM99_19225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKM99_19230	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FKM99_19235	COG3706	GGDEF domain
FKM99_19265	COG0393	Putative heavy-metal-binding
FKM99_19275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FKM99_19285	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FKM99_19300	COG2188	Transcriptional regulator
FKM99_19305	COG1228	amidohydrolase
FKM99_19310	COG0010	Belongs to the arginase family
FKM99_19315	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FKM99_19320	COG2986	histidine ammonia-lyase
FKM99_19335	COG0277	FAD linked oxidase domain protein
FKM99_19335	COG0247	lactate metabolic process
FKM99_19370	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FKM99_19385	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FKM99_19390	COG1643	Atp-dependent helicase
FKM99_19395	COG0281	malic enzyme
FKM99_19400	COG2949	membrane
FKM99_19405	COG0471	metal ion transport
FKM99_19410	COG3706	GGDEF domain
FKM99_19410	COG0745	RESPONSE REGULATOR receiver
FKM99_19430	COG0492	ferredoxin-NADP+ reductase activity
FKM99_19435	COG4988	ABC transporter
FKM99_19440	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FKM99_19445	COG3048	D-serine ammonia-lyase activity
FKM99_19450	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FKM99_19460	COG4191	Histidine kinase
FKM99_19460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKM99_19475	COG3070	regulator of competence-specific genes
FKM99_19495	COG2431	L-lysine efflux transmembrane transporter activity
FKM99_19505	COG0076	glutamate decarboxylase activity
FKM99_19510	COG1737	Transcriptional regulator
FKM99_19525	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FKM99_19530	COG3273	potassium ion transport
FKM99_19530	COG2985	domain, Protein
FKM99_19535	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FKM99_19550	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FKM99_19565	COG4181	ATPase activity
FKM99_19570	COG0534	Mate efflux family protein
FKM99_19575	COG0702	epimerase
FKM99_19580	COG3005	denitrification pathway
FKM99_19610	COG2814	Major facilitator Superfamily
FKM99_19615	COG1187	pseudouridine synthase activity
FKM99_19620	COG1061	Type III restriction enzyme res subunit
FKM99_19630	COG0745	RESPONSE REGULATOR receiver
FKM99_19635	COG2205	protein histidine kinase activity
FKM99_19640	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FKM99_19670	COG3313	Fe-S protein
FKM99_19695	COG0493	'glutamate synthase
FKM99_19705	COG0398	Pfam SNARE associated Golgi protein
FKM99_19710	COG4134	Bacterial extracellular solute-binding protein
FKM99_19715	COG4135	transport system, permease component
FKM99_19720	COG4136	ATPase activity
FKM99_19725	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FKM99_19740	COG3604	Transcriptional regulator
FKM99_19745	COG1151	hydroxylamine reductase activity
FKM99_19750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FKM99_19760	COG0564	pseudouridine synthase activity
FKM99_19770	COG0733	neurotransmitter:sodium symporter activity
FKM99_19780	COG0626	cystathionine gamma-synthase activity
FKM99_19785	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FKM99_19790	COG5380	lipid catabolic process
FKM99_19795	COG0519	Catalyzes the synthesis of GMP from XMP
FKM99_19810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKM99_19815	COG1983	PspC domain protein
FKM99_19825	COG1842	Phage shock protein A
FKM99_19830	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FKM99_19840	COG4168	peptide transport system, permease
FKM99_19845	COG4171	peptide transport system, permease
FKM99_19855	COG4172	Belongs to the ABC transporter superfamily
FKM99_19865	COG1227	inorganic diphosphatase activity
FKM99_19880	COG0243	molybdopterin cofactor binding
FKM99_19885	COG3005	denitrification pathway
FKM99_19890	COG4459	periplasmic nitrate reductase
FKM99_19895	COG0390	transport system, permease component
FKM99_19905	COG2116	formate transmembrane transporter activity
FKM99_19930	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FKM99_19935	COG1435	thymidine kinase activity
FKM99_19940	COG0215	cysteine-tRNA ligase activity
FKM99_19945	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FKM99_19950	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKM99_19955	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FKM99_19965	COG3012	SEC-C Motif Domain Protein
FKM99_19970	COG0140	phosphoribosyl-ATP diphosphatase activity
FKM99_19970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FKM99_19975	COG0107	imidazoleglycerol-phosphate synthase activity
FKM99_19980	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FKM99_19985	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FKM99_19990	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FKM99_19990	COG0131	Imidazoleglycerol-phosphate dehydratase
FKM99_19995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FKM99_20000	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FKM99_20005	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FKM99_20020	COG1757	Na H antiporter
FKM99_20030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FKM99_20040	COG0482	sulfurtransferase activity
FKM99_20045	COG2915	High frequency lysogenization protein hflD homolog
FKM99_20050	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FKM99_20075	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FKM99_20090	COG0300	oxidoreductase activity
FKM99_20100	COG0501	Belongs to the peptidase M48B family
FKM99_20110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FKM99_20120	COG0156	8-amino-7-oxononanoate synthase activity
FKM99_20125	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FKM99_20130	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FKM99_20135	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FKM99_20140	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FKM99_20145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FKM99_20150	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FKM99_20155	COG1674	ftsk spoiiie
FKM99_20165	COG0686	Belongs to the AlaDH PNT family
FKM99_20175	COG0583	DNA-binding transcription factor activity
FKM99_20190	COG3568	Endonuclease Exonuclease Phosphatase
FKM99_20220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKM99_20225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKM99_20240	COG0840	transmembrane signaling receptor activity
FKM99_20255	COG0784	Response regulator, receiver
FKM99_20255	COG5002	protein histidine kinase activity
FKM99_20265	COG0754	glutathionylspermidine amidase activity
FKM99_20275	COG3766	membrane
FKM99_20285	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FKM99_20290	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FKM99_20295	COG2885	chlorophyll binding
FKM99_20300	COG0823	Involved in the tonB-independent uptake of proteins
FKM99_20315	COG0811	peptide transport
FKM99_20320	COG0824	Thioesterase
FKM99_20330	COG4890	Cyd operon protein YbgT
FKM99_20335	COG1294	oxidase, subunit
FKM99_20340	COG1271	oxidase subunit
FKM99_20345	COG2255	four-way junction helicase activity
FKM99_20350	COG0632	four-way junction helicase activity
FKM99_20355	COG0840	transmembrane signaling receptor activity
FKM99_20360	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FKM99_20365	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FKM99_20370	COG1801	Protein of unknown function DUF72
FKM99_20375	COG4106	trans-aconitate 2-methyltransferase activity
FKM99_20380	COG0500	methyltransferase
FKM99_20390	COG4067	protein conserved in archaea
FKM99_20390	COG0189	ligase activity
FKM99_20410	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FKM99_20415	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FKM99_20420	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FKM99_20425	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FKM99_20430	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FKM99_20435	COG0745	RESPONSE REGULATOR receiver
FKM99_20440	COG3381	protein complex oligomerization
FKM99_20445	COG1609	Transcriptional regulator
FKM99_20450	COG3070	regulator of competence-specific genes
FKM99_20455	COG4584	PFAM Integrase catalytic
FKM99_20460	COG1484	DNA-dependent DNA replication
FKM99_20480	COG0297	glycogen (starch) synthase activity
FKM99_20485	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FKM99_20490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FKM99_20500	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FKM99_20510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FKM99_20515	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FKM99_20520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FKM99_20530	COG0542	response to heat
FKM99_20535	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FKM99_20540	COG1278	Cold shock
FKM99_20550	COG1187	pseudouridine synthase activity
FKM99_20555	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FKM99_20565	COG1199	ATP-dependent helicase activity
FKM99_20570	COG0730	response to heat
FKM99_20575	COG3923	Primosomal replication protein n
FKM99_20585	COG0708	Exodeoxyribonuclease III
FKM99_20600	COG4215	(ABC) transporter
FKM99_20630	COG1882	Formate acetyltransferase
FKM99_20640	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FKM99_20650	COG3013	Belongs to the UPF0304 family
FKM99_20660	COG2766	serine protein kinase
FKM99_20665	COG2718	Belongs to the UPF0229 family
FKM99_20670	COG2719	SpoVR family
FKM99_20675	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FKM99_20685	COG1663	tetraacyldisaccharide 4'-kinase activity
FKM99_20690	COG1132	(ABC) transporter
FKM99_20695	COG0658	competence protein
FKM99_20695	COG2333	competence protein COMEC
FKM99_20705	COG4591	ABC-type transport system involved in lipoprotein release permease component
FKM99_20710	COG1136	(ABC) transporter
FKM99_20715	COG4591	ABC-type transport system involved in lipoprotein release permease component
FKM99_20725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FKM99_20745	COG1252	NADH dehydrogenase
FKM99_20755	COG3150	esterase
FKM99_20780	COG0537	adenosine 5'-monophosphoramidase activity
FKM99_20810	COG0516	GMP reductase activity
FKM99_20810	COG0517	IMP dehydrogenase activity
FKM99_20820	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FKM99_20825	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FKM99_20830	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKM99_20840	COG2199	diguanylate cyclase activity
FKM99_20855	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FKM99_20860	COG1946	Acyl-CoA thioesterase
FKM99_20870	COG1522	sequence-specific DNA binding
FKM99_20900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKM99_20905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FKM99_20930	COG0477	Major facilitator Superfamily
FKM99_20935	COG2855	membrane
FKM99_20950	COG1441	menaquinone biosynthetic process
FKM99_20955	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FKM99_20960	COG0596	Alpha beta hydrolase
FKM99_20965	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FKM99_20970	COG1169	isochorismate synthase
FKM99_20975	COG0436	Aminotransferase
FKM99_20980	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FKM99_20985	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FKM99_21000	COG1555	photosystem II stabilization
FKM99_21005	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FKM99_21010	COG0776	regulation of translation
FKM99_21015	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FKM99_21020	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FKM99_21030	COG0544	peptidyl-prolyl cis-trans isomerase activity
FKM99_21040	COG2204	response regulator
FKM99_21050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FKM99_21055	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FKM99_21060	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FKM99_21065	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FKM99_21080	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FKM99_21085	COG0569	domain protein
FKM99_21090	COG0513	Belongs to the DEAD box helicase family
FKM99_21095	COG1253	flavin adenine dinucleotide binding
FKM99_21130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FKM99_21135	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FKM99_21150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FKM99_21155	COG1216	Glycosyl transferase, family 2
FKM99_21160	COG2986	histidine ammonia-lyase
FKM99_21185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FKM99_21190	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FKM99_21195	COG1028	Short-chain dehydrogenase reductase Sdr
FKM99_21215	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FKM99_21220	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FKM99_21225	COG0583	DNA-binding transcription factor activity
FKM99_21230	COG2951	lytic endotransglycosylase activity
FKM99_21235	COG3100	YcgL domain-containing protein
FKM99_21240	COG0850	regulation of cytokinetic process
FKM99_21245	COG2894	cell division
FKM99_21250	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FKM99_21255	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FKM99_21260	COG0318	PFAM AMP-dependent synthetase and ligase
FKM99_21265	COG2267	carboxylic ester hydrolase activity
FKM99_21280	COG1214	PFAM Peptidase M22, glycoprotease
FKM99_21285	COG1199	ATP-dependent helicase activity
FKM99_21290	COG0788	formyltetrahydrofolate deformylase activity
FKM99_21295	COG3102	Protein conserved in bacteria
FKM99_21305	COG0018	arginyl-trna synthetase
FKM99_21325	COG1918	ferrous iron import across plasma membrane
FKM99_21340	COG4977	sequence-specific DNA binding
FKM99_21345	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FKM99_21350	COG1121	(ABC) transporter
FKM99_21355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FKM99_21360	COG0121	glutamine amidotransferase
FKM99_21365	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FKM99_21370	COG1960	acyl-CoA dehydrogenase activity
FKM99_21380	COG0456	acetyltransferase
FKM99_21400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FKM99_21405	COG0328	RNA-DNA hybrid ribonuclease activity
FKM99_21410	COG2226	methyltransferase
FKM99_21415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FKM99_21420	COG1388	LysM domain
FKM99_21420	COG0741	lytic transglycosylase activity
FKM99_21430	COG3021	interspecies interaction between organisms
FKM99_21435	COG0347	Belongs to the P(II) protein family
FKM99_21445	COG0037	tRNA processing
FKM99_21450	COG0825	malonyl-CoA metabolic process
FKM99_21455	COG0587	DNA-directed DNA polymerase activity
FKM99_21465	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKM99_21470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FKM99_21475	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FKM99_21480	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FKM99_21490	COG0750	zinc metalloprotease
FKM99_21495	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FKM99_21500	COG0575	Belongs to the CDS family
FKM99_21505	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FKM99_21510	COG0233	cytoplasmic translational termination
FKM99_21515	COG0528	UMP kinase activity
FKM99_21520	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FKM99_21525	COG0052	Belongs to the universal ribosomal protein uS2 family
FKM99_21530	COG0024	Methionine aminopeptidase
FKM99_21535	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FKM99_21545	COG0564	pseudouridine synthase activity
FKM99_21550	COG3098	single-species biofilm formation
FKM99_21575	COG1671	Belongs to the UPF0178 family
FKM99_21580	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FKM99_21590	COG0254	rRNA binding
FKM99_21595	COG1720	tRNA m6t6A37 methyltransferase activity
FKM99_21600	COG0442	prolyl-tRNA aminoacylation
FKM99_21620	COG0733	neurotransmitter:sodium symporter activity
FKM99_21640	COG0514	ATP-dependent DNA helicase (RecQ)
FKM99_21645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FKM99_21660	COG1477	protein flavinylation
FKM99_21665	COG2871	sodium ion transport
FKM99_21670	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FKM99_21675	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FKM99_21680	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FKM99_21685	COG1805	sodium ion transport
FKM99_21690	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FKM99_21695	COG0271	Belongs to the BolA IbaG family
FKM99_21700	COG2813	Specifically methylates the guanine in position
FKM99_21705	COG3056	Lipoprotein
FKM99_21725	COG1595	DNA-templated transcription, initiation
FKM99_21755	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FKM99_21760	COG0693	protein deglycase activity
FKM99_21765	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FKM99_21770	COG3706	GGDEF domain
FKM99_21775	COG2166	iron-sulfur cluster assembly
FKM99_21780	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FKM99_21785	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FKM99_21800	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FKM99_21800	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FKM99_21810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FKM99_21815	COG1074	ATP-dependent DNA helicase activity
FKM99_21825	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FKM99_21845	COG3141	response to X-ray
FKM99_21850	COG2171	N-acyltransferase activity
FKM99_21855	COG0584	glycerophosphoryl diester phosphodiesterase
FKM99_21860	COG2271	Major facilitator Superfamily
FKM99_21875	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FKM99_21880	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FKM99_21885	COG1349	DNA-binding transcription factor activity
FKM99_21890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FKM99_21895	COG0598	Magnesium transport protein CorA
FKM99_21910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FKM99_21915	COG1609	Transcriptional regulator
FKM99_21920	COG2211	Major facilitator Superfamily
FKM99_21935	COG2017	converts alpha-aldose to the beta-anomer
FKM99_21940	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FKM99_21950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FKM99_21960	COG1609	Transcriptional regulator
FKM99_21965	COG3250	beta-galactosidase activity
FKM99_21970	COG2731	YhcH YjgK YiaL family protein
FKM99_21975	COG0531	amino acid
FKM99_21980	COG0583	DNA-binding transcription factor activity
FKM99_22045	COG4964	Belongs to the GSP D family
FKM99_22065	COG0583	DNA-binding transcription factor activity
FKM99_22105	COG1022	Amp-dependent synthetase and ligase
FKM99_22115	COG0583	DNA-binding transcription factor activity
FKM99_22120	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FKM99_22125	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
FKM99_22135	COG0560	Phosphoserine phosphatase
FKM99_22145	COG0813	purine-nucleoside phosphorylase activity
FKM99_22150	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FKM99_22155	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FKM99_22160	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FKM99_22165	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FKM99_22170	COG0084	hydrolase, TatD family'
FKM99_22180	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FKM99_22260	COG2003	Belongs to the UPF0758 family
FKM99_22285	COG0714	Associated with various cellular activities
FKM99_22300	COG0629	single-stranded DNA binding
FKM99_22315	COG2356	endonuclease I
FKM99_22345	COG0786	glutamate:sodium symporter activity
FKM99_22360	COG0640	Transcriptional regulator
FKM99_22410	COG0681	Belongs to the peptidase S26 family
FKM99_22425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FKM99_22535	COG2176	DNA-directed DNA polymerase activity
FKM99_22540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FKM99_22580	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FKM99_22600	COG3153	acetyltransferase
FKM99_22625	COG0534	Mate efflux family protein
FKM99_22640	COG1185	polyribonucleotide nucleotidyltransferase activity
FKM99_22645	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FKM99_22650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FKM99_22655	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FKM99_22660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FKM99_22665	COG0195	Participates in both transcription termination and antitermination
FKM99_22670	COG0779	Required for maturation of 30S ribosomal subunits
FKM99_22685	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FKM99_22695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FKM99_22700	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FKM99_22705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FKM99_22710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FKM99_22715	COG1534	Rna-binding protein
FKM99_22720	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FKM99_22725	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FKM99_22730	COG2027	D-alanyl-D-alanine carboxypeptidase
FKM99_22740	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FKM99_22745	COG0739	heme binding
FKM99_22750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FKM99_22760	COG0316	Belongs to the HesB IscA family
FKM99_22765	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FKM99_22770	COG0628	permease
FKM99_22775	COG2813	Specifically methylates the guanine in position
FKM99_22785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKM99_22785	COG2205	protein histidine kinase activity
FKM99_22785	COG2198	Histidine kinase
FKM99_22785	COG0784	Response regulator, receiver
FKM99_22790	COG0747	negative chemotaxis
FKM99_22800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FKM99_22805	COG0444	Belongs to the ABC transporter superfamily
FKM99_22810	COG4608	Belongs to the ABC transporter superfamily
FKM99_22820	COG2971	BadF BadG BcrA BcrD
FKM99_22835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FKM99_22840	COG3842	ATPase activity
FKM99_22850	COG1840	ABC-type Fe3 transport system, periplasmic component
FKM99_22855	COG0004	ammonium transporteR
FKM99_22865	COG3112	Uncharacterised protein family (UPF0231)
FKM99_22870	COG1049	propionate catabolic process, 2-methylcitrate cycle
FKM99_22875	COG1752	Esterase of the alpha-beta hydrolase superfamily
FKM99_22880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FKM99_22885	COG1643	Atp-dependent helicase
FKM99_22890	COG1489	DNA binding
FKM99_22895	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FKM99_22905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FKM99_22920	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FKM99_22925	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FKM99_22930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FKM99_22940	COG1560	Kdo2-lipid A biosynthetic process
FKM99_22950	COG0842	Transport permease protein
FKM99_22955	COG1131	(ABC) transporter
FKM99_22965	COG0659	secondary active sulfate transmembrane transporter activity
FKM99_22970	COG0288	reversible hydration of carbon dioxide
FKM99_22985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKM99_22990	COG0508	dehydrogenase complex catalyzes the overall conversion of
FKM99_22995	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FKM99_23000	COG2186	Transcriptional regulator
FKM99_23010	COG0157	Belongs to the NadC ModD family
FKM99_23020	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FKM99_23025	COG1459	type II secretion system
FKM99_23035	COG0237	dephospho-CoA kinase activity
FKM99_23040	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FKM99_23045	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FKM99_23050	COG0335	large ribosomal subunit rRNA binding
FKM99_23055	COG0336	Belongs to the RNA methyltransferase TrmD family
FKM99_23060	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FKM99_23065	COG0228	four-way junction DNA binding
FKM99_23070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FKM99_23075	COG4137	Cytochrome C assembly protein
FKM99_23080	COG4536	flavin adenine dinucleotide binding
FKM99_23085	COG1854	S-ribosylhomocysteine lyase activity
FKM99_23095	COG2918	glutathione biosynthetic process
FKM99_23100	COG0612	Peptidase, M16
FKM99_23105	COG1238	metal cluster binding
FKM99_23110	COG1063	alcohol dehydrogenase
FKM99_23115	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
FKM99_23120	COG0511	ligase activity, forming carbon-carbon bonds
FKM99_23120	COG5016	pyruvate
FKM99_23125	COG3630	sodium ion export across plasma membrane
FKM99_23150	COG0527	aspartate kinase activity
FKM99_23155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FKM99_23160	COG2137	regulation of response to DNA damage stimulus
FKM99_23165	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FKM99_23170	COG1546	Belongs to the CinA family
FKM99_23175	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FKM99_23190	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FKM99_23195	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FKM99_23200	COG0585	pseudouridine synthase activity
FKM99_23205	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FKM99_23210	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FKM99_23215	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FKM99_23220	COG0148	phosphopyruvate hydratase activity
FKM99_23225	COG0504	CTP synthase activity
FKM99_23230	COG3956	TIGRFAM MazG family protein
FKM99_23235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FKM99_23245	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FKM99_23260	COG0736	holo-[acyl-carrier-protein] synthase activity
FKM99_23265	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FKM99_23270	COG1381	Involved in DNA repair and RecF pathway recombination
FKM99_23275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FKM99_23280	COG0571	ribonuclease III activity
FKM99_23285	COG0681	Belongs to the peptidase S26 family
FKM99_23290	COG0481	GTPase activity
FKM99_23295	COG3086	response to oxidative stress
FKM99_23305	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FKM99_23310	COG1595	DNA-templated transcription, initiation
FKM99_23320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FKM99_23330	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FKM99_23335	COG0354	folic acid binding
FKM99_23350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKM99_23355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FKM99_23360	COG3079	Belongs to the UPF0149 family
FKM99_23370	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FKM99_23380	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FKM99_23385	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FKM99_23390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FKM99_23400	COG0583	DNA-binding transcription factor activity
FKM99_23415	COG0668	transmembrane transport
FKM99_23420	COG0191	fructose-bisphosphate aldolase activity
FKM99_23430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FKM99_23435	COG4771	TonB-dependent receptor
FKM99_23440	COG0583	DNA-binding transcription factor activity
FKM99_23445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FKM99_23455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FKM99_23465	COG3091	SprT-like family
FKM99_23470	COG2356	endonuclease I
FKM99_23475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FKM99_23480	COG0189	ligase activity
FKM99_23485	COG1678	Uncharacterized ACR, COG1678
FKM99_23490	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FKM99_23505	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FKM99_23510	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FKM99_23515	COG0762	integral membrane protein
FKM99_23520	COG1872	DUF167
FKM99_23530	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FKM99_23535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FKM99_23540	COG2066	Belongs to the glutaminase family
FKM99_23550	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FKM99_23560	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FKM99_23565	COG0741	lytic transglycosylase activity
FKM99_23635	COG1012	belongs to the aldehyde dehydrogenase family
FKM99_23685	COG3437	response regulator, receiver
FKM99_23695	COG3394	polysaccharide catabolic process
FKM99_23700	COG1486	melibiose metabolic process
FKM99_23705	COG1447	Phosphotransferase system cellobiose-specific component IIA
FKM99_23710	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FKM99_23715	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FKM99_23720	COG0726	polysaccharide deacetylase
FKM99_23735	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FKM99_23740	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FKM99_23840	COG1028	Short-chain dehydrogenase reductase Sdr
FKM99_23845	COG4325	translation initiation factor activity
FKM99_23855	COG0795	lipopolysaccharide-transporting ATPase activity
FKM99_23860	COG0795	lipopolysaccharide-transporting ATPase activity
FKM99_23865	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FKM99_23870	COG2927	DNA polymerase III (CHI subunit)
FKM99_23875	COG0525	valine-tRNA ligase activity
FKM99_23905	COG2235	arginine
FKM99_23910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FKM99_23920	COG0540	Belongs to the ATCase OTCase family
FKM99_23925	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FKM99_23930	COG0251	oxidation-reduction process
FKM99_23935	COG0204	Acyl-transferase
FKM99_23940	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FKM99_23945	COG5007	Belongs to the BolA IbaG family
FKM99_23955	COG2854	intermembrane phospholipid transfer
FKM99_23960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FKM99_23965	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FKM99_23970	COG1127	ABC transporter
FKM99_23980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FKM99_23980	COG0517	IMP dehydrogenase activity
FKM99_23990	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FKM99_23995	COG1137	ATPase activity
FKM99_24005	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FKM99_24010	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FKM99_24015	COG1660	Displays ATPase and GTPase activities
FKM99_24020	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FKM99_24025	COG2239	Acts as a magnesium transporter
FKM99_24030	COG0312	modulator of DNA gyrase
FKM99_24035	COG3028	Belongs to the UPF0307 family
FKM99_24040	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FKM99_24045	COG0564	pseudouridine synthase activity
FKM99_24060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FKM99_24065	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FKM99_24070	COG0312	modulator of DNA gyrase
FKM99_24075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FKM99_24080	COG3164	Protein of unknown function
FKM99_24085	COG1530	ribonuclease E activity
FKM99_24090	COG0424	maF-like protein
FKM99_24095	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FKM99_24100	COG1792	Involved in formation and maintenance of cell shape
FKM99_24105	COG1077	Cell shape determining protein MreB Mrl
FKM99_24150	COG1459	type II secretion system
FKM99_24155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FKM99_24165	COG3267	Type II secretory pathway component ExeA
FKM99_24165	COG3409	Peptidoglycan-binding domain 1 protein
FKM99_24190	COG2200	EAL domain
FKM99_24190	COG2199	diguanylate cyclase activity
FKM99_24220	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FKM99_24265	COG0840	transmembrane signaling receptor activity
FKM99_24290	COG1061	Type III restriction enzyme res subunit
FKM99_24315	COG0629	single-stranded DNA binding
FKM99_24330	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FKM99_24340	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FKM99_24350	COG0527	aspartate kinase activity
FKM99_24355	COG0646	methionine synthase
FKM99_24355	COG1410	methionine synthase
FKM99_24435	COG0175	sulfate reduction
FKM99_24440	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FKM99_24445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FKM99_24470	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FKM99_24475	COG0582	viral genome integration into host DNA
FKM99_24490	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FKM99_24545	COG0735	belongs to the Fur family
FKM99_24555	COG0166	Belongs to the GPI family
FKM99_24560	COG0432	Pfam Uncharacterised protein family UPF0047
FKM99_24570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FKM99_24575	COG0305	Participates in initiation and elongation during chromosome replication
FKM99_24585	COG0359	binds to the 23S rRNA
FKM99_24595	COG2965	DNA replication, synthesis of RNA primer
FKM99_24600	COG0360	Binds together with S18 to 16S ribosomal RNA
FKM99_24605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FKM99_24610	COG0338	D12 class N6 adenine-specific DNA methyltransferase
FKM99_24620	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FKM99_24625	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FKM99_24655	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FKM99_24665	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FKM99_24665	COG0678	peroxiredoxin activity
FKM99_24680	COG0165	Argininosuccinate lyase
FKM99_24680	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FKM99_24685	COG0137	argininosuccinate synthase activity
FKM99_24690	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FKM99_24695	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FKM99_24700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FKM99_24705	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FKM99_24715	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FKM99_24720	COG0460	homoserine dehydrogenase
FKM99_24720	COG0527	aspartate kinase activity
FKM99_24725	COG0626	cystathionine gamma-synthase activity
FKM99_24735	COG0281	malic enzyme
FKM99_24745	COG2906	2 iron, 2 sulfur cluster binding
FKM99_24750	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FKM99_24755	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FKM99_24760	COG0049	tRNA binding
FKM99_24770	COG2168	tRNA wobble position uridine thiolation
FKM99_24775	COG2923	Belongs to the DsrF TusC family
FKM99_24780	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FKM99_24785	COG2964	Protein conserved in bacteria
FKM99_24790	COG0545	Peptidyl-prolyl cis-trans isomerase
FKM99_24800	COG2900	Belongs to the SlyX family
FKM99_24805	COG1446	asparaginase
FKM99_24815	COG1047	Peptidyl-prolyl cis-trans
FKM99_24830	COG2249	NAD(P)H dehydrogenase (quinone) activity
FKM99_24840	COG0488	(ABC) transporter
FKM99_24850	COG0429	hydrolase of the alpha beta-hydrolase fold
FKM99_24855	COG3089	Belongs to the UPF0270 family
FKM99_24860	COG3954	Phosphoribulokinase
FKM99_24865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FKM99_24875	COG1012	belongs to the aldehyde dehydrogenase family
FKM99_24885	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FKM99_24890	COG0512	Glutamine amidotransferase of anthranilate synthase
FKM99_24920	COG0180	Tryptophanyl-tRNA synthetase
FKM99_24925	COG0546	phosphoglycolate phosphatase activity
FKM99_24930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FKM99_24935	COG0557	exoribonuclease II activity
FKM99_24940	COG1959	2 iron, 2 sulfur cluster binding
FKM99_24945	COG1017	nitric oxide dioxygenase activity
FKM99_24945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FKM99_24950	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
FKM99_24960	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FKM99_24965	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FKM99_24970	COG0330	HflC and HflK could
FKM99_24975	COG0330	HflC and HflK could
FKM99_24980	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FKM99_24990	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FKM99_24995	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FKM99_25000	COG0860	N-Acetylmuramoyl-L-alanine amidase
FKM99_25005	COG0802	atpase or kinase
FKM99_25010	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FKM99_25040	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FKM99_25045	COG1162	GTPase activity
FKM99_25050	COG0688	phosphatidylethanolamine metabolic process
FKM99_25055	COG0471	metal ion transport
FKM99_25070	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FKM99_25080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FKM99_25085	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FKM99_25090	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FKM99_25095	COG1045	serine acetyltransferase
FKM99_25100	COG4942	peptidase
FKM99_25120	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FKM99_25130	COG1053	succinate dehydrogenase
FKM99_25135	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FKM99_25140	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FKM99_25145	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FKM99_25155	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FKM99_25160	COG1509	lysine 2,3-aminomutase activity
FKM99_25175	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FKM99_25190	COG0459	protein refolding
FKM99_25195	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FKM99_25200	COG0534	Mate efflux family protein
FKM99_25205	COG0205	6-phosphofructokinase activity
FKM99_25215	COG3678	ATP-independent chaperone mediated protein folding
FKM99_25225	COG0745	RESPONSE REGULATOR receiver
FKM99_25230	COG2205	protein histidine kinase activity
FKM99_25240	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FKM99_25245	COG3030	protein affecting phage T7 exclusion by the F plasmid
FKM99_25250	COG1027	Aspartate ammonia-lyase
FKM99_25255	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FKM99_25260	COG4232	protein-disulfide reductase activity
FKM99_25270	COG3263	regulation of cellular component size
FKM99_25280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FKM99_25305	COG2205	protein histidine kinase activity
FKM99_25305	COG0784	Response regulator, receiver
FKM99_25310	COG2814	Major facilitator Superfamily
FKM99_25325	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FKM99_25330	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FKM99_25335	COG0511	ligase activity, forming carbon-carbon bonds
FKM99_25340	COG0439	Biotin carboxylase
FKM99_25350	COG2264	protein methyltransferase activity
FKM99_25355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FKM99_25360	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FKM99_25365	COG2814	Major facilitator Superfamily
FKM99_25370	COG0488	(ABC) transporter
FKM99_25375	COG3706	GGDEF domain
FKM99_25445	COG1982	Orn Lys Arg decarboxylase major
FKM99_25450	COG0531	amino acid
FKM99_25460	COG3710	Transcriptional regulator
FKM99_25465	COG0789	Transcriptional regulator
FKM99_25475	COG0138	bifunctional purine biosynthesis protein purh
FKM99_25485	COG0151	Belongs to the GarS family
FKM99_25500	COG1253	flavin adenine dinucleotide binding
FKM99_25505	COG3068	Protein conserved in bacteria
FKM99_25510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FKM99_25515	COG1573	uracil-dna glycosylase
FKM99_25520	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FKM99_25535	COG2816	NAD+ diphosphatase activity
FKM99_25540	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FKM99_25545	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FKM99_25550	COG0085	RNA polymerase activity
FKM99_25555	COG0222	ribosome binding
FKM99_25560	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FKM99_25565	COG0081	regulation of translation
FKM99_25570	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FKM99_25575	COG0250	Participates in transcription elongation, termination and antitermination
FKM99_25580	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FKM99_25590	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FKM99_25630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FKM99_25640	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FKM99_25710	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FKM99_25720	COG4206	TonB-dependent receptor
FKM99_25725	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FKM99_25740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FKM99_25745	COG0534	Mate efflux family protein
FKM99_25750	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FKM99_25755	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FKM99_25770	COG2937	Belongs to the GPAT DAPAT family
FKM99_25775	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FKM99_25780	COG3161	chorismate lyase activity
FKM99_25785	COG1580	Controls the rotational direction of flagella during chemotaxis
FKM99_25790	COG0705	Rhomboid family
FKM99_25795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FKM99_25810	COG2177	Part of the ABC transporter FtsEX involved in
FKM99_25815	COG2884	Cell division ATP-binding protein ftsE
FKM99_25820	COG0552	protein localization to endoplasmic reticulum
FKM99_25825	COG0742	ribosomal rna small subunit methyltransferase
FKM99_25835	COG2095	MarC family integral membrane protein
FKM99_25890	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FKM99_25895	COG0640	Transcriptional regulator
FKM99_25900	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FKM99_25905	COG1280	lysine exporter protein (LysE YggA)
FKM99_25910	COG2267	carboxylic ester hydrolase activity
FKM99_25920	COG0561	phosphatase activity
FKM99_25940	COG2199	diguanylate cyclase activity
FKM99_25940	COG3287	FIST C domain
FKM99_25940	COG2200	EAL domain
FKM99_25945	COG1011	Hydrolase
FKM99_25950	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FKM99_25960	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FKM99_25965	COG0019	diaminopimelate decarboxylase activity
FKM99_25975	COG1965	Belongs to the frataxin family
FKM99_25980	COG3072	Adenylate cyclase
FKM99_25985	COG0181	hydroxymethylbilane synthase activity
FKM99_25990	COG1587	Uroporphyrinogen-III synthase
FKM99_25995	COG2959	enzyme of heme biosynthesis
FKM99_26000	COG3071	HemY protein
FKM99_26050	COG0633	Ferredoxin
FKM99_26055	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FKM99_26070	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FKM99_26075	COG3118	belongs to the thioredoxin family
FKM99_26080	COG0513	Belongs to the DEAD box helicase family
FKM99_26085	COG0248	Ppx GppA phosphatase
FKM99_26090	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FKM99_26105	COG0514	ATP-dependent DNA helicase (RecQ)
FKM99_26110	COG2962	Rard protein
FKM99_26120	COG1280	lysine exporter protein (LysE YggA)
FKM99_26125	COG0405	Gamma-glutamyltransferase
FKM99_26135	COG0210	DNA helicase
FKM99_26145	COG3220	belongs to the UPF0276 family
FKM99_26175	COG0006	proline dipeptidase activity
FKM99_26175	COG0006	proline dipeptidase activity
FKM99_26185	COG2022	thiamine diphosphate biosynthetic process
FKM99_26190	COG2104	thiamine diphosphate biosynthetic process
FKM99_26195	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FKM99_26200	COG0352	thiamine-phosphate diphosphorylase activity
FKM99_26205	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FKM99_26210	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FKM99_26265	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FKM99_26275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FKM99_26280	COG0408	coproporphyrinogen oxidase activity
FKM99_26285	COG0009	L-threonylcarbamoyladenylate synthase
FKM99_26290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FKM99_26295	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FKM99_26300	COG0551	DNA topoisomerase type I activity
FKM99_26305	COG2922	Belongs to the Smg family
FKM99_26310	COG0758	DNA mediated transformation
FKM99_26320	COG0242	peptide deformylase activity
FKM99_26325	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FKM99_26330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FKM99_26330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FKM99_26335	COG0569	domain protein
FKM99_26340	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FKM99_26350	COG1272	protein, Hemolysin III
FKM99_26355	COG4326	sporulation control protein
FKM99_26365	COG3084	Protein conserved in bacteria
FKM99_26375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FKM99_26380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FKM99_26385	COG0204	Acyl-transferase
FKM99_26395	COG0606	chelatase, subunit chli
FKM99_26405	COG3978	acetolactate synthase activity
FKM99_26410	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FKM99_26415	COG0129	dihydroxy-acid dehydratase activity
FKM99_26425	COG0583	DNA-binding transcription factor activity
FKM99_26430	COG2814	Major facilitator Superfamily
FKM99_26435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FKM99_26440	COG0765	amino acid transport
FKM99_26445	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FKM99_26450	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FKM99_26455	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FKM99_26460	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FKM99_26465	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FKM99_26470	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FKM99_26485	COG0356	it plays a direct role in the translocation of protons across the membrane
FKM99_26490	COG3312	ion transport
FKM99_26495	COG1475	DNA binding
FKM99_26500	COG1192	Involved in chromosome partitioning
FKM99_26505	COG0357	Ribosomal RNA small subunit methyltransferase G
FKM99_26510	COG0445	tRNA wobble uridine modification
FKM99_26515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FKM99_26535	COG1395	domain, Protein
FKM99_26590	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FKM99_26615	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FKM99_26640	COG4974	Belongs to the 'phage' integrase family
FKM99_26645	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FKM99_26650	COG0706	membrane insertase activity
FKM99_26655	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FKM99_26660	COG0594	ribonuclease P activity
FKM99_26670	COG1126	abc transporter atp-binding protein