locus-tag	class	description
H9J99_00050	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H9J99_00060	COG4206	TonB-dependent receptor
H9J99_00065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9J99_00105	COG3339	Conserved Protein
H9J99_00145	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H9J99_00180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9J99_00185	COG0534	Mate efflux family protein
H9J99_00190	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H9J99_00195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9J99_00200	COG2937	Belongs to the GPAT DAPAT family
H9J99_00205	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H9J99_00210	COG3161	chorismate lyase activity
H9J99_00215	COG1580	Controls the rotational direction of flagella during chemotaxis
H9J99_00220	COG0705	Rhomboid family
H9J99_00225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9J99_00235	COG2177	Part of the ABC transporter FtsEX involved in
H9J99_00240	COG2884	Cell division ATP-binding protein ftsE
H9J99_00245	COG0552	protein localization to endoplasmic reticulum
H9J99_00250	COG0742	ribosomal rna small subunit methyltransferase
H9J99_00260	COG2095	MarC family integral membrane protein
H9J99_00310	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9J99_00315	COG0640	Transcriptional regulator
H9J99_00320	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H9J99_00325	COG1280	lysine exporter protein (LysE YggA)
H9J99_00330	COG2267	carboxylic ester hydrolase activity
H9J99_00335	COG0561	phosphatase activity
H9J99_00350	COG3148	PFAM DTW domain containing protein
H9J99_00355	COG3287	FIST C domain
H9J99_00355	COG2200	EAL domain
H9J99_00355	COG2199	diguanylate cyclase activity
H9J99_00360	COG1011	Hydrolase
H9J99_00375	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H9J99_00380	COG0019	diaminopimelate decarboxylase activity
H9J99_00390	COG1965	Belongs to the frataxin family
H9J99_00395	COG3072	Adenylate cyclase
H9J99_00400	COG0181	hydroxymethylbilane synthase activity
H9J99_00405	COG1587	Uroporphyrinogen-III synthase
H9J99_00410	COG2959	enzyme of heme biosynthesis
H9J99_00415	COG3071	HemY protein
H9J99_00455	COG0633	Ferredoxin
H9J99_00460	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
H9J99_00475	COG3118	belongs to the thioredoxin family
H9J99_00480	COG0513	Belongs to the DEAD box helicase family
H9J99_00485	COG0248	Ppx GppA phosphatase
H9J99_00490	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H9J99_00500	COG0514	ATP-dependent DNA helicase (RecQ)
H9J99_00505	COG2962	Rard protein
H9J99_00515	COG1280	lysine exporter protein (LysE YggA)
H9J99_00520	COG0405	Gamma-glutamyltransferase
H9J99_00525	COG0210	DNA helicase
H9J99_00535	COG3220	belongs to the UPF0276 family
H9J99_00565	COG0006	proline dipeptidase activity
H9J99_00565	COG0006	proline dipeptidase activity
H9J99_00580	COG2022	thiamine diphosphate biosynthetic process
H9J99_00585	COG2104	thiamine diphosphate biosynthetic process
H9J99_00590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9J99_00600	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
H9J99_00605	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H9J99_00655	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9J99_00660	COG1739	Uncharacterized protein family UPF0029
H9J99_00665	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9J99_00665	COG1024	Enoyl-CoA hydratase
H9J99_00670	COG0183	Belongs to the thiolase family
H9J99_00675	COG0604	alcohol dehydrogenase
H9J99_00690	COG0425	Belongs to the sulfur carrier protein TusA family
H9J99_00700	COG2119	membrane
H9J99_00705	COG0752	glycyl-tRNA synthetase alpha subunit
H9J99_00710	COG0751	glycine-tRNA ligase activity
H9J99_00715	COG0366	Alpha amylase catalytic
H9J99_00720	COG3977	Valine--pyruvate aminotransferase
H9J99_00725	COG0071	Belongs to the small heat shock protein (HSP20) family
H9J99_00735	COG0187	DNA topoisomerase II activity
H9J99_00740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H9J99_00745	COG0592	DNA-directed DNA polymerase activity
H9J99_00750	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H9J99_00765	COG1126	abc transporter atp-binding protein
H9J99_00775	COG0594	ribonuclease P activity
H9J99_00785	COG0706	membrane insertase activity
H9J99_00790	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H9J99_00795	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H9J99_00800	COG0445	tRNA wobble uridine modification
H9J99_00810	COG1192	Involved in chromosome partitioning
H9J99_00815	COG1475	DNA binding
H9J99_00820	COG3312	ion transport
H9J99_00825	COG0356	it plays a direct role in the translocation of protons across the membrane
H9J99_00840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9J99_00850	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H9J99_00855	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9J99_00860	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H9J99_00865	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H9J99_00870	COG0765	amino acid transport
H9J99_00875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9J99_00880	COG2814	Major facilitator Superfamily
H9J99_00885	COG0583	DNA-binding transcription factor activity
H9J99_00895	COG0129	dihydroxy-acid dehydratase activity
H9J99_00900	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H9J99_00905	COG3978	acetolactate synthase activity
H9J99_00915	COG0606	chelatase, subunit chli
H9J99_00925	COG0204	Acyl-transferase
H9J99_00930	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9J99_00935	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H9J99_00945	COG3084	Protein conserved in bacteria
H9J99_00955	COG4326	sporulation control protein
H9J99_00960	COG1272	protein, Hemolysin III
H9J99_00970	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9J99_00975	COG0569	domain protein
H9J99_00980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9J99_00980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9J99_00985	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9J99_00990	COG0242	peptide deformylase activity
H9J99_01000	COG0758	DNA mediated transformation
H9J99_01005	COG2922	Belongs to the Smg family
H9J99_01010	COG0551	DNA topoisomerase type I activity
H9J99_01015	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H9J99_01020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9J99_01025	COG0009	L-threonylcarbamoyladenylate synthase
H9J99_01030	COG0408	coproporphyrinogen oxidase activity
H9J99_01035	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9J99_01045	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H9J99_01080	COG0583	DNA-binding transcription factor activity
H9J99_01085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9J99_01090	COG2960	long-chain fatty acid transporting porin activity
H9J99_01095	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9J99_01100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9J99_01150	COG4172	Belongs to the ABC transporter superfamily
H9J99_01155	COG0747	negative chemotaxis
H9J99_01160	COG0601	transmembrane transport
H9J99_01165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9J99_01200	COG1609	Transcriptional regulator
H9J99_01205	COG0583	DNA-binding transcription factor activity
H9J99_01220	COG0129	dihydroxy-acid dehydratase activity
H9J99_01225	COG3265	gluconokinase activity
H9J99_01230	COG2610	gluconate transmembrane transporter activity
H9J99_01235	COG0800	Aldolase
H9J99_01240	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
H9J99_01245	COG0583	DNA-binding transcription factor activity
H9J99_01250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9J99_01255	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H9J99_01260	COG0339	signal peptide processing
H9J99_01265	COG1522	sequence-specific DNA binding
H9J99_01270	COG5001	Diguanylate cyclase
H9J99_01270	COG5002	protein histidine kinase activity
H9J99_01275	COG0742	ribosomal rna small subunit methyltransferase
H9J99_01290	COG0589	response to stress
H9J99_01295	COG1528	Iron-storage protein
H9J99_01305	COG2081	HI0933 family
H9J99_01320	COG2823	Periplasmic or secreted lipoprotein
H9J99_01370	COG0628	permease
H9J99_01385	COG1322	Protein conserved in bacteria
H9J99_01390	COG2226	methyltransferase
H9J99_01395	COG3165	ubiquinone biosynthetic process from chorismate
H9J99_01400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9J99_01405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9J99_01410	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9J99_01415	COG0805	protein transport
H9J99_01420	COG0084	hydrolase, TatD family'
H9J99_01440	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9J99_01440	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9J99_01475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H9J99_01485	COG2204	response regulator
H9J99_01490	COG3852	Histidine kinase
H9J99_01500	COG0174	glutamine synthetase
H9J99_01505	COG1217	gtp-binding protein TYPA
H9J99_01520	COG1295	ribonuclease BN
H9J99_01525	COG1490	D-aminoacyl-tRNA deacylase activity
H9J99_01530	COG0456	acetyltransferase
H9J99_01540	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
H9J99_01545	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H9J99_01550	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H9J99_01555	COG3031	protein transport across the cell outer membrane
H9J99_01565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9J99_01570	COG1459	type II secretion system
H9J99_01575	COG2165	general secretion pathway protein
H9J99_01580	COG2165	general secretion pathway protein
H9J99_01585	COG2165	general secretion pathway protein
H9J99_01590	COG4795	General secretion pathway protein
H9J99_01595	COG3156	type II secretion system protein K
H9J99_01600	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H9J99_01605	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
H9J99_01615	COG1218	3'(2'),5'-bisphosphate nucleotidase
H9J99_01620	COG0494	nUDIX hydrolase
H9J99_01625	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
H9J99_01625	COG0316	Belongs to the HesB IscA family
H9J99_01630	COG1040	competence protein
H9J99_01635	COG0596	Alpha beta hydrolase
H9J99_01645	COG2183	response to ionizing radiation
H9J99_01655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9J99_01675	COG2233	PERMEase
H9J99_01680	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9J99_01685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9J99_01690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9J99_01695	COG1758	RNA polymerase activity
H9J99_01700	COG0194	GDP metabolic process
H9J99_01715	COG0848	biopolymer transport protein
H9J99_01720	COG0811	peptide transport
H9J99_01740	COG4174	ABC transporter (Permease)
H9J99_01745	COG4239	(ABC) transporter, permease
H9J99_01750	COG0747	negative chemotaxis
H9J99_01755	COG0444	Belongs to the ABC transporter superfamily
H9J99_01760	COG4608	Belongs to the ABC transporter superfamily
H9J99_01770	COG1561	YicC-like family, N-terminal region
H9J99_01775	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
H9J99_01780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H9J99_01785	COG1560	Kdo2-lipid A biosynthetic process
H9J99_01790	COG1309	transcriptional regulator
H9J99_01795	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H9J99_01805	COG2003	Belongs to the UPF0758 family
H9J99_01810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H9J99_01825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H9J99_01850	COG0463	Glycosyl transferase, family 2
H9J99_01855	COG0859	PFAM glycosyl transferase family 9
H9J99_01860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9J99_01865	COG3642	lipopolysaccharide core region biosynthetic process
H9J99_01885	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9J99_01910	COG1021	2,3-dihydroxybenzoate-AMP ligase
H9J99_01915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9J99_01930	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9J99_01935	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H9J99_01940	COG2089	acid synthase
H9J99_01950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H9J99_01955	COG1083	cytidylyl-transferase
H9J99_01965	COG1519	Transferase
H9J99_01970	COG0859	PFAM glycosyl transferase family 9
H9J99_01975	COG1560	Kdo2-lipid A biosynthetic process
H9J99_01985	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9J99_02035	COG1215	transferase activity, transferring glycosyl groups
H9J99_02040	COG0438	transferase activity, transferring glycosyl groups
H9J99_02095	COG4932	domain protein
H9J99_02095	COG5492	domain, Protein
H9J99_02120	COG0149	triose-phosphate isomerase activity
H9J99_02145	COG1494	fructose-1,6-bisphosphatase
H9J99_02150	COG3074	FtsZ-dependent cytokinesis
H9J99_02155	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9J99_02160	COG1575	Belongs to the MenA family. Type 1 subfamily
H9J99_02165	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H9J99_02170	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H9J99_02180	COG1609	Transcriptional regulator
H9J99_02185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H9J99_02190	COG0254	rRNA binding
H9J99_02200	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9J99_02205	COG0088	Forms part of the polypeptide exit tunnel
H9J99_02215	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9J99_02220	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H9J99_02225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9J99_02230	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H9J99_02240	COG0255	Belongs to the universal ribosomal protein uL29 family
H9J99_02245	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9J99_02250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H9J99_02255	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H9J99_02260	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H9J99_02265	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9J99_02270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
H9J99_02275	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H9J99_02290	COG1841	ribosomal large subunit assembly
H9J99_02295	COG0200	Binds to the 23S rRNA
H9J99_02300	COG0201	protein transport
H9J99_02305	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H9J99_02310	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9J99_02315	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9J99_02325	COG0202	RNA polymerase activity
H9J99_02330	COG0203	ribosomal protein L17
H9J99_02340	COG0545	Peptidyl-prolyl cis-trans isomerase
H9J99_02350	COG2153	protein acetylation
H9J99_02355	COG0513	Belongs to the DEAD box helicase family
H9J99_02365	COG0737	Belongs to the 5'-nucleotidase family
H9J99_02370	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H9J99_02370	COG1648	precorrin-2 dehydrogenase activity
H9J99_02375	COG0175	sulfate reduction
H9J99_02380	COG2895	sulfate adenylyltransferase (ATP) activity
H9J99_02385	COG0471	metal ion transport
H9J99_02385	COG3273	potassium ion transport
H9J99_02390	COG0529	Catalyzes the synthesis of activated sulfate
H9J99_02410	COG4181	ATPase activity
H9J99_02425	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H9J99_02435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9J99_02440	COG0729	surface antigen
H9J99_02445	COG2911	Protein conserved in bacteria
H9J99_02450	COG2105	PFAM AIG2 family protein
H9J99_02460	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H9J99_02465	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H9J99_02470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9J99_02475	COG0163	prenyltransferase activity
H9J99_02480	COG4143	(ABC) transporter
H9J99_02490	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
H9J99_02505	COG2358	TRAP transporter, solute receptor (TAXI family
H9J99_02515	COG0039	L-malate dehydrogenase activity
H9J99_02525	COG0142	geranyltranstransferase activity
H9J99_02530	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H9J99_02540	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9J99_02545	COG2966	Psort location CytoplasmicMembrane, score
H9J99_02560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H9J99_02565	COG2967	ApaG domain
H9J99_02570	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H9J99_02575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H9J99_02580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9J99_02585	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
H9J99_02590	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H9J99_02600	COG0066	3-isopropylmalate dehydratase activity
H9J99_02605	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
H9J99_02610	COG0473	3-isopropylmalate dehydrogenase activity
H9J99_02615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9J99_02635	COG0583	DNA-binding transcription factor activity
H9J99_02640	COG1022	Amp-dependent synthetase and ligase
H9J99_02645	COG0028	Belongs to the TPP enzyme family
H9J99_02650	COG0440	acetolactate synthase activity
H9J99_02665	COG0469	pyruvate kinase activity
H9J99_02670	COG1349	DNA-binding transcription factor activity
H9J99_02675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H9J99_02715	COG2826	transposase and inactivated derivatives, IS30 family
H9J99_02785	COG5002	protein histidine kinase activity
H9J99_02795	COG2376	Dihydroxyacetone kinase
H9J99_02800	COG1461	Dihydroxyacetone kinase
H9J99_02815	COG3722	fumarate hydratase activity
H9J99_02820	COG0246	Mannitol dehydrogenase
H9J99_02825	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9J99_02825	COG2213	PTS system mannitol-specific
H9J99_02855	COG1464	Belongs to the NlpA lipoprotein family
H9J99_02885	COG0840	transmembrane signaling receptor activity
H9J99_02920	COG0732	type I restriction modification DNA specificity domain
H9J99_02975	COG3550	peptidyl-serine autophosphorylation
H9J99_02995	COG0358	DNA primase activity
H9J99_03000	COG1610	YqeY-like protein
H9J99_03005	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H9J99_03010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H9J99_03015	COG0596	Alpha beta hydrolase
H9J99_03020	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9J99_03025	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H9J99_03030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9J99_03035	COG1968	undecaprenyl-diphosphatase activity
H9J99_03045	COG3409	Peptidoglycan-binding domain 1 protein
H9J99_03045	COG3267	Type II secretory pathway component ExeA
H9J99_03055	COG4991	sh3 domain protein
H9J99_03060	COG0306	phosphate transporter
H9J99_03065	COG1392	Phosphate transport regulator
H9J99_03070	COG3025	triphosphatase activity
H9J99_03085	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H9J99_03090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H9J99_03090	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H9J99_03095	COG1538	Outer membrane efflux protein
H9J99_03100	COG0494	nUDIX hydrolase
H9J99_03105	COG3151	Protein conserved in bacteria
H9J99_03115	COG3150	esterase
H9J99_03125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H9J99_03130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9J99_03140	COG3105	Protein conserved in bacteria
H9J99_03145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H9J99_03150	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H9J99_03155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9J99_03160	COG0723	plastoquinol--plastocyanin reductase activity
H9J99_03165	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H9J99_03170	COG2857	Cytochrome c1
H9J99_03175	COG0625	glutathione transferase activity
H9J99_03180	COG2969	positive regulation of protein catabolic process
H9J99_03185	COG2823	Periplasmic or secreted lipoprotein
H9J99_03190	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H9J99_03195	COG0792	nuclease activity
H9J99_03205	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H9J99_03215	COG0275	rRNA processing
H9J99_03220	COG3116	cell division
H9J99_03225	COG0768	penicillin binding
H9J99_03230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9J99_03235	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9J99_03240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9J99_03245	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H9J99_03250	COG0772	Belongs to the SEDS family
H9J99_03255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H9J99_03260	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9J99_03265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H9J99_03270	COG0849	cell division
H9J99_03275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H9J99_03280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H9J99_03290	COG0653	protein targeting
H9J99_03295	COG0494	nUDIX hydrolase
H9J99_03300	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H9J99_03305	COG0505	Belongs to the CarA family
H9J99_03310	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
H9J99_03325	COG0730	response to heat
H9J99_03330	COG0583	DNA-binding transcription factor activity
H9J99_03335	COG2860	membrane
H9J99_03340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9J99_03350	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H9J99_03360	COG0493	'glutamate synthase
H9J99_03365	COG0070	glutamate synthase
H9J99_03365	COG0067	glutamate synthase
H9J99_03365	COG0069	glutamate synthase activity
H9J99_03375	COG0067	glutamate synthase
H9J99_03375	COG0069	glutamate synthase activity
H9J99_03375	COG0070	glutamate synthase
H9J99_03380	COG1242	4 iron, 4 sulfur cluster binding
H9J99_03385	COG2203	Gaf domain
H9J99_03385	COG3706	GGDEF domain
H9J99_03385	COG4251	negative regulation of phosphorylation
H9J99_03385	COG5001	Diguanylate cyclase
H9J99_03390	COG0784	Response regulator, receiver
H9J99_03390	COG2198	Histidine kinase
H9J99_03390	COG5002	protein histidine kinase activity
H9J99_03400	COG0745	RESPONSE REGULATOR receiver
H9J99_03410	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9J99_03430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H9J99_03435	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
H9J99_03440	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
H9J99_03445	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9J99_03460	COG1115	amino acid carrier protein
H9J99_03465	COG3022	response to hydroperoxide
H9J99_03470	COG0513	Belongs to the DEAD box helicase family
H9J99_03475	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
H9J99_03485	COG0716	FMN binding
H9J99_03490	COG4974	Belongs to the 'phage' integrase family
H9J99_03495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9J99_03510	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H9J99_03525	COG0667	Aldo Keto reductase
H9J99_03535	COG3066	DNA modification
H9J99_03540	COG0494	nUDIX hydrolase
H9J99_03550	COG0730	response to heat
H9J99_03555	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
H9J99_03560	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H9J99_03570	COG1283	sodium-dependent phosphate transmembrane transporter activity
H9J99_03575	COG0583	DNA-binding transcription factor activity
H9J99_03580	COG0640	Transcriptional regulator
H9J99_03585	COG0268	Binds directly to 16S ribosomal RNA
H9J99_03590	COG0728	peptidoglycan biosynthetic process
H9J99_03595	COG0196	riboflavin kinase activity
H9J99_03600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H9J99_03605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H9J99_03610	COG1047	Peptidyl-prolyl cis-trans
H9J99_03615	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9J99_03625	COG3275	phosphorelay sensor kinase activity
H9J99_03630	COG1966	Carbon starvation protein
H9J99_03645	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H9J99_03650	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H9J99_03655	COG1472	Belongs to the glycosyl hydrolase 3 family
H9J99_03660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H9J99_03665	COG1605	Chorismate mutase
H9J99_03665	COG0287	Prephenate dehydrogenase
H9J99_03670	COG0739	heme binding
H9J99_03690	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
H9J99_03695	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
H9J99_03700	COG1605	Chorismate mutase
H9J99_03700	COG0077	Prephenate dehydratase
H9J99_03705	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H9J99_03710	COG0741	lytic transglycosylase activity
H9J99_03715	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9J99_03720	COG0564	pseudouridine synthase activity
H9J99_03730	COG0542	response to heat
H9J99_03785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9J99_03790	COG0826	peptidase U32
H9J99_03795	COG2974	May be involved in recombination
H9J99_03800	COG0745	RESPONSE REGULATOR receiver
H9J99_03805	COG5002	protein histidine kinase activity
H9J99_03815	COG0248	Ppx GppA phosphatase
H9J99_03820	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H9J99_03830	COG0581	inorganic phosphate transmembrane transporter activity
H9J99_03835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9J99_03840	COG0704	Plays a role in the regulation of phosphate uptake
H9J99_03850	COG3142	Participates in the control of copper homeostasis
H9J99_03855	COG0450	alkyl hydroperoxide reductase
H9J99_03860	COG0583	DNA-binding transcription factor activity
H9J99_03865	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H9J99_03875	COG0517	IMP dehydrogenase activity
H9J99_03885	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H9J99_03890	COG0343	queuine tRNA-ribosyltransferase activity
H9J99_03895	COG1862	Preprotein translocase
H9J99_03900	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9J99_03905	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9J99_03910	COG0483	inositol monophosphate 1-phosphatase activity
H9J99_03925	COG1104	cysteine desulfurase activity
H9J99_03930	COG0822	iron-sulfur transferase activity
H9J99_03940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H9J99_03945	COG0443	Heat shock 70 kDa protein
H9J99_03950	COG0633	Ferredoxin
H9J99_03955	COG2975	iron-sulfur cluster assembly
H9J99_03960	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9J99_03965	COG0105	UTP biosynthetic process
H9J99_03970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9J99_03980	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H9J99_03985	COG0124	histidyl-tRNA synthetase
H9J99_03990	COG2976	Protein conserved in bacteria
H9J99_03995	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9J99_04000	COG1160	GTP binding
H9J99_04015	COG1570	exodeoxyribonuclease VII activity
H9J99_04020	COG0517	IMP dehydrogenase activity
H9J99_04020	COG0516	GMP reductase activity
H9J99_04025	COG0519	Catalyzes the synthesis of GMP from XMP
H9J99_04025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9J99_04030	COG1757	Na H antiporter
H9J99_04040	COG1584	GPR1 FUN34 yaaH family protein
H9J99_04050	COG1115	amino acid carrier protein
H9J99_04080	COG2873	o-acetylhomoserine
H9J99_04085	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9J99_04105	COG3153	acetyltransferase
H9J99_04105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9J99_04110	COG0583	DNA-binding transcription factor activity
H9J99_04225	COG0582	viral genome integration into host DNA
H9J99_04235	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9J99_04240	COG2867	negative regulation of translational initiation
H9J99_04245	COG2914	Belongs to the UPF0125 (RnfH) family
H9J99_04250	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9J99_04255	COG0497	DNA recombination
H9J99_04265	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H9J99_04270	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9J99_04285	COG0443	Heat shock 70 kDa protein
H9J99_04290	COG0484	heat shock protein binding
H9J99_04320	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H9J99_04330	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
H9J99_04335	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9J99_04335	COG0047	phosphoribosylformylglycinamidine synthase activity
H9J99_04360	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9J99_04365	COG2252	PERMEase
H9J99_04370	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
H9J99_04375	COG1073	alpha beta
H9J99_04385	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9J99_04390	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
H9J99_04395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9J99_04400	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9J99_04400	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9J99_04420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9J99_04425	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H9J99_04430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H9J99_04435	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9J99_04440	COG0142	geranyltranstransferase activity
H9J99_04445	COG1722	exodeoxyribonuclease VII activity
H9J99_04450	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9J99_04455	COG2885	chlorophyll binding
H9J99_04460	COG0301	tRNA thio-modification
H9J99_04460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9J99_04465	COG0583	DNA-binding transcription factor activity
H9J99_04475	COG2363	Small membrane protein
H9J99_04480	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
H9J99_04490	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9J99_04495	COG1611	Belongs to the LOG family
H9J99_04510	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9J99_04510	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9J99_04520	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
H9J99_04525	COG1464	Belongs to the NlpA lipoprotein family
H9J99_04530	COG2011	ABC-type metal ion transport system permease component
H9J99_04535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9J99_04540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9J99_04550	COG1263	PTS System
H9J99_04550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9J99_04555	COG0366	Alpha amylase catalytic
H9J99_04565	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9J99_04570	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9J99_04575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H9J99_04580	COG0321	lipoyl(octanoyl) transferase activity
H9J99_04585	COG2921	Belongs to the UPF0250 family
H9J99_04590	COG1686	Belongs to the peptidase S11 family
H9J99_04595	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H9J99_04600	COG0772	Belongs to the SEDS family
H9J99_04605	COG0768	penicillin binding
H9J99_04610	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9J99_04615	COG0799	negative regulation of ribosome biogenesis
H9J99_04620	COG1466	dna polymerase III delta subunit
H9J99_04625	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
H9J99_04630	COG0495	leucyl-tRNA aminoacylation
H9J99_04635	COG2888	peptidyl-tyrosine sulfation
H9J99_04640	COG0815	Transfers the fatty acyl group on membrane lipoproteins
H9J99_04645	COG4535	Mg2 and Co2 transporter CorC
H9J99_04650	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9J99_04655	COG1702	phosphate starvation-inducible protein PhoH
H9J99_04660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9J99_04665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9J99_04780	COG0012	GTP binding
H9J99_04785	COG0193	aminoacyl-tRNA hydrolase activity
H9J99_04790	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9J99_04795	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H9J99_04800	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H9J99_04805	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H9J99_04810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9J99_04815	COG2890	protein-(glutamine-N5) methyltransferase activity
H9J99_04820	COG3094	Invasion gene expression up-regulator, SirB
H9J99_04825	COG2912	Transglutaminase-like superfamily
H9J99_04830	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H9J99_04835	COG0737	Belongs to the 5'-nucleotidase family
H9J99_04845	COG1187	pseudouridine synthase activity
H9J99_04850	COG2840	Smr protein MutS2
H9J99_04885	COG2608	mercury ion transmembrane transporter activity
H9J99_04885	COG2217	Heavy metal translocating P-type atpase
H9J99_04895	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H9J99_04900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9J99_04950	COG0835	chemotaxis
H9J99_04950	COG0784	Response regulator, receiver
H9J99_04955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H9J99_04960	COG1815	bacterial-type flagellum-dependent cell motility
H9J99_04965	COG1558	bacterial-type flagellum-dependent cell motility
H9J99_04975	COG1749	Flagellar hook protein flgE
H9J99_04980	COG4787	bacterial-type flagellum-dependent cell motility
H9J99_04990	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H9J99_04995	COG1706	bacterial-type flagellum-dependent cell motility
H9J99_05000	COG3951	Flagellar rod assembly protein muramidase FlgJ
H9J99_05000	COG1705	Flagellar rod assembly protein muramidase FlgJ
H9J99_05010	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9J99_05015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9J99_05020	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9J99_05025	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9J99_05030	COG2190	(PTS) system
H9J99_05035	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9J99_05040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9J99_05045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H9J99_05050	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
H9J99_05055	COG3115	cell septum assembly
H9J99_05060	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9J99_05080	COG0330	HflC and HflK could
H9J99_05085	COG2194	sulfuric ester hydrolase activity
H9J99_05110	COG1215	transferase activity, transferring glycosyl groups
H9J99_05115	COG1215	transferase activity, transferring glycosyl groups
H9J99_05120	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H9J99_05125	COG0457	Tetratricopeptide repeat
H9J99_05125	COG3118	belongs to the thioredoxin family
H9J99_05130	COG3118	belongs to the thioredoxin family
H9J99_05135	COG0300	oxidoreductase activity
H9J99_05140	COG1090	epimerase
H9J99_05165	COG0622	Phosphoesterase
H9J99_05185	COG3710	Transcriptional regulator
H9J99_05190	COG0326	Molecular chaperone. Has ATPase activity
H9J99_05195	COG0563	adenylate kinase activity
H9J99_05200	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
H9J99_05205	COG3104	oligopeptide transport
H9J99_05210	COG0250	Participates in transcription elongation, termination and antitermination
H9J99_05220	COG4651	solute:proton antiporter activity
H9J99_05220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9J99_05230	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
H9J99_05235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9J99_05235	COG1263	PTS System
H9J99_05240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9J99_05245	COG0735	belongs to the Fur family
H9J99_05265	COG0596	Alpha beta hydrolase
H9J99_05270	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
H9J99_05275	COG0033	Phosphoglucomutase
H9J99_05300	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H9J99_05305	COG1053	succinate dehydrogenase
H9J99_05310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H9J99_05315	COG0567	Dehydrogenase, E1 component
H9J99_05320	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9J99_05325	COG0045	succinate-CoA ligase (ADP-forming) activity
H9J99_05335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H9J99_05345	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
H9J99_05350	COG4977	sequence-specific DNA binding
H9J99_05355	COG1918	ferrous iron import across plasma membrane
H9J99_05375	COG0018	arginyl-trna synthetase
H9J99_05385	COG0788	formyltetrahydrofolate deformylase activity
H9J99_05390	COG1199	ATP-dependent helicase activity
H9J99_05395	COG1214	PFAM Peptidase M22, glycoprotease
H9J99_05410	COG2267	carboxylic ester hydrolase activity
H9J99_05415	COG0318	PFAM AMP-dependent synthetase and ligase
H9J99_05420	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H9J99_05430	COG2894	cell division
H9J99_05440	COG3100	YcgL domain-containing protein
H9J99_05445	COG2951	lytic endotransglycosylase activity
H9J99_05450	COG0583	DNA-binding transcription factor activity
H9J99_05455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9J99_05460	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H9J99_05470	COG4974	Belongs to the 'phage' integrase family
H9J99_05490	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H9J99_05495	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H9J99_05500	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H9J99_05505	COG0732	type I restriction modification DNA specificity domain
H9J99_05545	COG1028	Short-chain dehydrogenase reductase Sdr
H9J99_05555	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9J99_05580	COG2986	histidine ammonia-lyase
H9J99_05585	COG1216	Glycosyl transferase, family 2
H9J99_05590	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9J99_05605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9J99_05610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9J99_05645	COG1253	flavin adenine dinucleotide binding
H9J99_05650	COG0513	Belongs to the DEAD box helicase family
H9J99_05655	COG0569	domain protein
H9J99_05660	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9J99_05675	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H9J99_05680	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9J99_05685	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H9J99_05690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9J99_05700	COG2204	response regulator
H9J99_05715	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9J99_05725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H9J99_05730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H9J99_05735	COG0776	regulation of translation
H9J99_05740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9J99_05745	COG1555	photosystem II stabilization
H9J99_05760	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H9J99_05765	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
H9J99_05770	COG0436	Aminotransferase
H9J99_05775	COG1169	isochorismate synthase
H9J99_05780	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
H9J99_05785	COG0596	Alpha beta hydrolase
H9J99_05790	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
H9J99_05810	COG2855	membrane
H9J99_05815	COG0477	Major facilitator Superfamily
H9J99_05865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9J99_05935	COG0753	catalase activity
H9J99_05950	COG0783	Belongs to the Dps family
H9J99_05970	COG0489	protein tyrosine kinase activity
H9J99_05985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9J99_05990	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9J99_06040	COG0640	Transcriptional regulator
H9J99_06065	COG0789	Transcriptional regulator
H9J99_06070	COG2801	Transposase and inactivated derivatives
H9J99_06115	COG1522	sequence-specific DNA binding
H9J99_06125	COG1946	Acyl-CoA thioesterase
H9J99_06130	COG3126	Type III secretion system lipoprotein chaperone (YscW)
H9J99_06145	COG2199	diguanylate cyclase activity
H9J99_06155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9J99_06160	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H9J99_06165	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
H9J99_06170	COG0516	GMP reductase activity
H9J99_06170	COG0517	IMP dehydrogenase activity
H9J99_06195	COG0537	adenosine 5'-monophosphoramidase activity
H9J99_06220	COG3150	esterase
H9J99_06225	COG1252	NADH dehydrogenase
H9J99_06240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H9J99_06250	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9J99_06255	COG1136	(ABC) transporter
H9J99_06260	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9J99_06275	COG1132	(ABC) transporter
H9J99_06280	COG1663	tetraacyldisaccharide 4'-kinase activity
H9J99_06290	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H9J99_06295	COG2719	SpoVR family
H9J99_06300	COG2718	Belongs to the UPF0229 family
H9J99_06305	COG2766	serine protein kinase
H9J99_06310	COG3013	Belongs to the UPF0304 family
H9J99_06320	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H9J99_06330	COG1882	Formate acetyltransferase
H9J99_06370	COG0708	Exodeoxyribonuclease III
H9J99_06380	COG3923	Primosomal replication protein n
H9J99_06385	COG0730	response to heat
H9J99_06390	COG1199	ATP-dependent helicase activity
H9J99_06395	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H9J99_06400	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H9J99_06405	COG1187	pseudouridine synthase activity
H9J99_06415	COG1278	Cold shock
H9J99_06420	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H9J99_06425	COG0542	response to heat
H9J99_06435	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H9J99_06440	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
H9J99_06445	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H9J99_06455	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H9J99_06465	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9J99_06470	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H9J99_06475	COG0297	glycogen (starch) synthase activity
H9J99_06495	COG3070	regulator of competence-specific genes
H9J99_06500	COG1609	Transcriptional regulator
H9J99_06505	COG3381	protein complex oligomerization
H9J99_06510	COG0745	RESPONSE REGULATOR receiver
H9J99_06515	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H9J99_06520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9J99_06525	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
H9J99_06530	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
H9J99_06535	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H9J99_06555	COG0189	ligase activity
H9J99_06555	COG4067	protein conserved in archaea
H9J99_06560	COG0500	methyltransferase
H9J99_06565	COG4106	trans-aconitate 2-methyltransferase activity
H9J99_06570	COG1801	Protein of unknown function DUF72
H9J99_06575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
H9J99_06580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H9J99_06585	COG0840	transmembrane signaling receptor activity
H9J99_06590	COG0632	four-way junction helicase activity
H9J99_06595	COG2255	four-way junction helicase activity
H9J99_06600	COG1271	oxidase subunit
H9J99_06605	COG1294	oxidase, subunit
H9J99_06610	COG4890	Cyd operon protein YbgT
H9J99_06620	COG0824	Thioesterase
H9J99_06625	COG0811	peptide transport
H9J99_06640	COG0823	Involved in the tonB-independent uptake of proteins
H9J99_06645	COG2885	chlorophyll binding
H9J99_06650	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
H9J99_06655	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H9J99_06665	COG3766	membrane
H9J99_06675	COG0754	glutathionylspermidine amidase activity
H9J99_06685	COG0784	Response regulator, receiver
H9J99_06685	COG5002	protein histidine kinase activity
H9J99_06705	COG0840	transmembrane signaling receptor activity
H9J99_06710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9J99_06715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9J99_06740	COG3568	Endonuclease Exonuclease Phosphatase
H9J99_06755	COG0583	DNA-binding transcription factor activity
H9J99_06765	COG0686	Belongs to the AlaDH PNT family
H9J99_06775	COG1674	ftsk spoiiie
H9J99_06780	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H9J99_06785	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9J99_06790	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H9J99_06805	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H9J99_06810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H9J99_06815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
H9J99_06830	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
H9J99_06840	COG0501	Belongs to the peptidase M48B family
H9J99_06850	COG0300	oxidoreductase activity
H9J99_06865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9J99_06885	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H9J99_06890	COG2915	High frequency lysogenization protein hflD homolog
H9J99_06895	COG0482	sulfurtransferase activity
H9J99_06905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9J99_06920	COG1757	Na H antiporter
H9J99_06935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H9J99_06940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H9J99_06945	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9J99_06950	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9J99_06950	COG0131	Imidazoleglycerol-phosphate dehydratase
H9J99_06955	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H9J99_06960	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H9J99_06965	COG0107	imidazoleglycerol-phosphate synthase activity
H9J99_06970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H9J99_06970	COG0140	phosphoribosyl-ATP diphosphatase activity
H9J99_06975	COG3012	SEC-C Motif Domain Protein
H9J99_06980	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H9J99_06985	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9J99_06990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9J99_06995	COG0215	cysteine-tRNA ligase activity
H9J99_07000	COG1435	thymidine kinase activity
H9J99_07005	COG1434	Gram-negative-bacterium-type cell wall biogenesis
H9J99_07030	COG2116	formate transmembrane transporter activity
H9J99_07045	COG0390	transport system, permease component
H9J99_07050	COG4459	periplasmic nitrate reductase
H9J99_07055	COG3005	denitrification pathway
H9J99_07060	COG0243	molybdopterin cofactor binding
H9J99_07075	COG1227	inorganic diphosphatase activity
H9J99_07085	COG4172	Belongs to the ABC transporter superfamily
H9J99_07095	COG4171	peptide transport system, permease
H9J99_07110	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
H9J99_07115	COG1842	Phage shock protein A
H9J99_07125	COG1983	PspC domain protein
H9J99_07130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9J99_07145	COG2818	Glycosylase
H9J99_07150	COG5380	lipid catabolic process
H9J99_07155	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
H9J99_07160	COG0626	cystathionine gamma-synthase activity
H9J99_07170	COG0733	neurotransmitter:sodium symporter activity
H9J99_07180	COG0564	pseudouridine synthase activity
H9J99_07190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H9J99_07195	COG1151	hydroxylamine reductase activity
H9J99_07200	COG3604	Transcriptional regulator
H9J99_07210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H9J99_07215	COG4136	ATPase activity
H9J99_07220	COG4135	transport system, permease component
H9J99_07225	COG4134	Bacterial extracellular solute-binding protein
H9J99_07230	COG0398	Pfam SNARE associated Golgi protein
H9J99_07240	COG0493	'glutamate synthase
H9J99_07265	COG3313	Fe-S protein
H9J99_07275	COG0737	Belongs to the 5'-nucleotidase family
H9J99_07290	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H9J99_07310	COG1061	Type III restriction enzyme res subunit
H9J99_07315	COG1187	pseudouridine synthase activity
H9J99_07320	COG2814	Major facilitator Superfamily
H9J99_07350	COG3005	denitrification pathway
H9J99_07355	COG0702	epimerase
H9J99_07360	COG0534	Mate efflux family protein
H9J99_07365	COG4181	ATPase activity
H9J99_07380	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H9J99_07395	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H9J99_07400	COG2985	domain, Protein
H9J99_07400	COG3273	potassium ion transport
H9J99_07405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H9J99_07420	COG1737	Transcriptional regulator
H9J99_07425	COG0076	glutamate decarboxylase activity
H9J99_07435	COG2431	L-lysine efflux transmembrane transporter activity
H9J99_07460	COG4191	Histidine kinase
H9J99_07460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9J99_07470	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H9J99_07475	COG3048	D-serine ammonia-lyase activity
H9J99_07480	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
H9J99_07485	COG4988	ABC transporter
H9J99_07490	COG0492	ferredoxin-NADP+ reductase activity
H9J99_07515	COG0471	metal ion transport
H9J99_07520	COG2949	membrane
H9J99_07525	COG0281	malic enzyme
H9J99_07530	COG1643	Atp-dependent helicase
H9J99_07535	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
H9J99_07550	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9J99_07585	COG0247	lactate metabolic process
H9J99_07585	COG0277	FAD linked oxidase domain protein
H9J99_07600	COG2986	histidine ammonia-lyase
H9J99_07605	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H9J99_07615	COG1228	amidohydrolase
H9J99_07620	COG2188	Transcriptional regulator
H9J99_07635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9J99_07645	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H9J99_07655	COG0393	Putative heavy-metal-binding
H9J99_07685	COG3706	GGDEF domain
H9J99_07690	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9J99_07695	COG0072	phenylalanine-tRNA ligase activity
H9J99_07695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9J99_07705	COG0776	regulation of translation
H9J99_07715	COG0500	methyltransferase
H9J99_07720	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
H9J99_07725	COG0295	cytidine deaminase activity
H9J99_07730	COG1346	cytolysis
H9J99_07735	COG1380	Effector of murein hydrolase LrgA
H9J99_07740	COG2925	Exonuclease
H9J99_07750	COG0702	epimerase
H9J99_07760	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H9J99_07765	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
H9J99_07785	COG2988	succinylglutamate desuccinylase activity
H9J99_07790	COG4139	cobalamin transport
H9J99_07795	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
H9J99_07815	COG0583	DNA-binding transcription factor activity
H9J99_07835	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H9J99_07840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9J99_07845	COG3475	LICD family
H9J99_07850	COG1451	nucleotide metabolic process
H9J99_07855	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
H9J99_07885	COG3938	Belongs to the proline racemase family
H9J99_07900	COG2423	ornithine cyclodeaminase activity
H9J99_07905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9J99_07910	COG3842	ATPase activity
H9J99_07915	COG1176	ABC-type spermidine putrescine transport system, permease component I
H9J99_07920	COG1177	transmembrane transport
H9J99_07930	COG3291	Pkd domain containing protein
H9J99_07950	COG0444	Belongs to the ABC transporter superfamily
H9J99_07955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9J99_07960	COG0601	transmembrane transport
H9J99_07970	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9J99_07985	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
H9J99_07995	COG0625	glutathione transferase activity
H9J99_08030	COG2826	transposase and inactivated derivatives, IS30 family
H9J99_08045	COG1278	Cold shock
H9J99_08060	COG0557	exoribonuclease II activity
H9J99_08095	COG0471	metal ion transport
H9J99_08100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9J99_08100	COG4191	Histidine kinase
H9J99_08110	COG3300	MHYT domain
H9J99_08110	COG5001	Diguanylate cyclase
H9J99_08120	COG1280	lysine exporter protein (LysE YggA)
H9J99_08125	COG1328	CTP reductase activity
H9J99_08130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H9J99_08140	COG0861	Integral membrane protein TerC family
H9J99_08150	COG1368	sulfuric ester hydrolase activity
H9J99_08155	COG0642	Histidine kinase
H9J99_08160	COG0745	RESPONSE REGULATOR receiver
H9J99_08170	COG1028	Short-chain dehydrogenase reductase Sdr
H9J99_08190	COG2113	Glycine betaine
H9J99_08195	COG4176	ABC-type proline glycine betaine transport system permease component
H9J99_08215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9J99_08220	COG0456	acetyltransferase
H9J99_08225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H9J99_08230	COG0662	Cupin 2, conserved barrel domain protein
H9J99_08235	COG0527	aspartate kinase activity
H9J99_08260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9J99_08275	COG3290	protein histidine kinase activity
H9J99_08280	COG4565	transcriptional regulatory protein
H9J99_08285	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9J99_08290	COG0363	glucosamine-6-phosphate deaminase activity
H9J99_08295	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H9J99_08310	COG3284	Transcriptional regulator
H9J99_08315	COG1012	belongs to the aldehyde dehydrogenase family
H9J99_08385	COG4669	(LipO)protein
H9J99_08405	COG3177	Filamentation induced by cAMP protein fic
H9J99_08430	COG4792	protein secretion
H9J99_08435	COG4791	protein targeting
H9J99_08440	COG4794	Type iii secretion
H9J99_08445	COG4790	Type iii secretion
H9J99_08515	COG0457	Tetratricopeptide repeat
H9J99_08535	COG0730	response to heat
H9J99_08565	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
H9J99_08570	COG0372	Belongs to the citrate synthase family
H9J99_08580	COG2828	Protein conserved in bacteria
H9J99_08605	COG0561	phosphatase activity
H9J99_08610	COG0602	queuosine metabolic process
H9J99_08615	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H9J99_08620	COG3706	GGDEF domain
H9J99_08660	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9J99_08665	COG0840	transmembrane signaling receptor activity
H9J99_08670	COG1254	Belongs to the acylphosphatase family
H9J99_08675	COG2920	part of a sulfur-relay system
H9J99_08685	COG0670	Belongs to the BI1 family
H9J99_08690	COG1126	abc transporter atp-binding protein
H9J99_08695	COG0765	amino acid transport
H9J99_08700	COG4597	amino acid ABC transporter
H9J99_08705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9J99_08715	COG1666	GTP binding
H9J99_08720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H9J99_08740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9J99_08740	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
H9J99_08750	COG2995	paraquat-inducible protein a
H9J99_08755	COG1132	(ABC) transporter
H9J99_08760	COG1956	GAF domain-containing protein
H9J99_08765	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
H9J99_08780	COG0308	aminopeptidase N
H9J99_08795	COG0167	dihydroorotate dehydrogenase activity
H9J99_08805	COG0116	Belongs to the methyltransferase superfamily
H9J99_08805	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9J99_08815	COG0488	(ABC) transporter
H9J99_08830	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9J99_08835	COG1067	ATP-dependent peptidase activity
H9J99_08840	COG3120	sequence-specific DNA binding
H9J99_08860	COG2205	protein histidine kinase activity
H9J99_08860	COG0784	Response regulator, receiver
H9J99_08875	COG3278	Belongs to the heme-copper respiratory oxidase family
H9J99_08890	COG2010	Cytochrome c
H9J99_08900	COG2217	Heavy metal translocating P-type atpase
H9J99_08915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9J99_08920	COG0589	response to stress
H9J99_08925	COG0037	tRNA processing
H9J99_08945	COG3842	ATPase activity
H9J99_08955	COG1177	transmembrane transport
H9J99_08965	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
H9J99_08970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9J99_08980	COG0004	ammonium transporteR
H9J99_09030	COG0437	4 iron, 4 sulfur cluster binding
H9J99_09035	COG0243	molybdopterin cofactor binding
H9J99_09035	COG3383	formate dehydrogenase (NAD+) activity
H9J99_09045	COG3381	protein complex oligomerization
H9J99_09065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H9J99_09070	COG0488	(ABC) transporter
H9J99_09080	COG2204	response regulator
H9J99_09095	COG3842	ATPase activity
H9J99_09100	COG0746	molybdenum cofactor guanylyltransferase activity
H9J99_09115	COG1940	carbohydrate kinase activity
H9J99_09120	COG3148	PFAM DTW domain containing protein
H9J99_09155	COG3290	protein histidine kinase activity
H9J99_09155	COG0840	transmembrane signaling receptor activity
H9J99_09160	COG0791	NLP P60 protein
H9J99_09170	COG3706	GGDEF domain
H9J99_09175	COG2201	protein-glutamate methylesterase activity
H9J99_09180	COG3001	Fructosamine kinase
H9J99_09190	COG0307	riboflavin synthase, alpha
H9J99_09195	COG0534	Mate efflux family protein
H9J99_09205	COG1793	dna ligase
H9J99_09235	COG2204	response regulator
H9J99_09245	COG0438	transferase activity, transferring glycosyl groups
H9J99_09275	COG0438	transferase activity, transferring glycosyl groups
H9J99_09280	COG1215	transferase activity, transferring glycosyl groups
H9J99_09285	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H9J99_09295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9J99_09310	COG1643	Atp-dependent helicase
H9J99_09315	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9J99_09330	COG3302	dmso reductase anchor subunit
H9J99_09335	COG0437	4 iron, 4 sulfur cluster binding
H9J99_09340	COG0243	molybdopterin cofactor binding
H9J99_09370	COG3706	GGDEF domain
H9J99_09380	COG0443	Heat shock 70 kDa protein
H9J99_09385	COG0443	Heat shock 70 kDa protein
H9J99_09410	COG1132	(ABC) transporter
H9J99_09415	COG1132	(ABC) transporter
H9J99_09435	COG0814	amino acid
H9J99_09445	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H9J99_09470	COG1115	amino acid carrier protein
H9J99_09480	COG1280	lysine exporter protein (LysE YggA)
H9J99_09485	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
H9J99_09490	COG1560	Kdo2-lipid A biosynthetic process
H9J99_09495	COG0531	amino acid
H9J99_09505	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
H9J99_09510	COG3063	Type IV pilus biogenesis stability protein PilW
H9J99_09540	COG0110	maltose O-acetyltransferase activity
H9J99_09560	COG2315	Protein conserved in bacteria
H9J99_09565	COG1846	Transcriptional regulator
H9J99_09590	COG2200	EAL domain
H9J99_09590	COG2771	luxR family
H9J99_09595	COG1227	inorganic diphosphatase activity
H9J99_09600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H9J99_09605	COG1012	belongs to the aldehyde dehydrogenase family
H9J99_09610	COG2957	Belongs to the agmatine deiminase family
H9J99_09620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9J99_09625	COG1012	belongs to the aldehyde dehydrogenase family
H9J99_09630	COG1396	sequence-specific DNA binding
H9J99_09630	COG1917	Cupin 2, conserved barrel domain protein
H9J99_09635	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H9J99_09640	COG0174	glutamine synthetase
H9J99_09645	COG1757	Na H antiporter
H9J99_09675	COG0583	DNA-binding transcription factor activity
H9J99_09690	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H9J99_09700	COG2985	domain, Protein
H9J99_09725	COG2272	Belongs to the type-B carboxylesterase lipase family
H9J99_09730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9J99_09735	COG0729	surface antigen
H9J99_09795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9J99_09800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9J99_09845	COG0582	viral genome integration into host DNA
H9J99_09860	COG0456	acetyltransferase
H9J99_10020	COG1484	DNA-dependent DNA replication
H9J99_10025	COG4584	PFAM Integrase catalytic
H9J99_10055	COG3153	acetyltransferase
H9J99_10285	COG1280	lysine exporter protein (LysE YggA)
H9J99_10375	COG0840	transmembrane signaling receptor activity
H9J99_10380	COG4580	involved in the transport of maltose and maltodextrins
H9J99_10385	COG1874	Beta-galactosidase
H9J99_10395	COG3833	ABC-type maltose transport systems, permease component
H9J99_10400	COG1175	transmembrane transport
H9J99_10405	COG2182	Extracellular solute-binding protein
H9J99_10415	COG1609	Transcriptional regulator
H9J99_10430	COG3547	Transposase (IS116 IS110 IS902 family)
H9J99_10435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9J99_10450	COG2211	Major facilitator Superfamily
H9J99_10460	COG4580	involved in the transport of maltose and maltodextrins
H9J99_10470	COG3250	beta-galactosidase activity
H9J99_10475	COG1609	Transcriptional regulator
H9J99_10500	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9J99_10575	COG0456	acetyltransferase
H9J99_10755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9J99_10765	COG3768	UPF0283 membrane protein
H9J99_10770	COG3106	COG3106 Predicted ATPase
H9J99_10785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9J99_10800	COG0494	nUDIX hydrolase
H9J99_10805	COG0814	amino acid
H9J99_10810	COG1760	l-serine dehydratase
H9J99_10815	COG2200	EAL domain
H9J99_10825	COG0720	synthase
H9J99_10830	COG0840	transmembrane signaling receptor activity
H9J99_10835	COG0017	Asparaginyl-tRNA synthetase
H9J99_10845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9J99_10860	COG1448	Aminotransferase
H9J99_10880	COG0840	transmembrane signaling receptor activity
H9J99_10885	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9J99_10890	COG1846	Transcriptional regulator
H9J99_10915	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H9J99_10930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9J99_10935	COG3108	Peptidase M15
H9J99_10940	COG2989	Protein conserved in bacteria
H9J99_10965	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9J99_10975	COG3088	subunit of a heme lyase
H9J99_10975	COG4235	cytochrome complex assembly
H9J99_10985	COG1138	Cytochrome C-type biogenesis protein
H9J99_10990	COG3301	Polysulphide reductase, NrfD
H9J99_10995	COG0437	4 iron, 4 sulfur cluster binding
H9J99_11005	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
H9J99_11025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9J99_11030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9J99_11035	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9J99_11060	COG0019	diaminopimelate decarboxylase activity
H9J99_11105	COG2197	response regulator
H9J99_11110	COG0417	DNA replication proofreading
H9J99_11120	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9J99_11125	COG3099	Belongs to the UPF0263 family
H9J99_11130	COG1187	pseudouridine synthase activity
H9J99_11140	COG0009	L-threonylcarbamoyladenylate synthase
H9J99_11145	COG0613	PHP domain protein
H9J99_11155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H9J99_11160	COG0512	Glutamine amidotransferase of anthranilate synthase
H9J99_11165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9J99_11170	COG0134	indole-3-glycerol-phosphate synthase activity
H9J99_11170	COG0135	phosphoribosylanthranilate isomerase activity
H9J99_11175	COG0133	tryptophan synthase activity
H9J99_11180	COG0159	tryptophan synthase activity
H9J99_11185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9J99_11190	COG0318	PFAM AMP-dependent synthetase and ligase
H9J99_11195	COG1301	dicarboxylic acid transport
H9J99_11215	COG2917	probably involved in intracellular septation
H9J99_11225	COG2350	Protein conserved in bacteria
H9J99_11235	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H9J99_11240	COG0583	DNA-binding transcription factor activity
H9J99_11255	COG2203	Gaf domain
H9J99_11255	COG3706	GGDEF domain
H9J99_11255	COG4251	negative regulation of phosphorylation
H9J99_11255	COG5001	Diguanylate cyclase
H9J99_11260	COG1032	radical SAM domain protein
H9J99_11265	COG0840	transmembrane signaling receptor activity
H9J99_11270	COG0745	RESPONSE REGULATOR receiver
H9J99_11275	COG3850	Histidine kinase
H9J99_11275	COG5002	protein histidine kinase activity
H9J99_11325	COG1335	isochorismatase
H9J99_11330	COG1136	(ABC) transporter
H9J99_11330	COG0577	efflux transmembrane transporter activity
H9J99_11335	COG1136	(ABC) transporter
H9J99_11335	COG0577	efflux transmembrane transporter activity
H9J99_11350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9J99_11370	COG3118	belongs to the thioredoxin family
H9J99_11375	COG4232	protein-disulfide reductase activity
H9J99_11415	COG2863	cytochrome
H9J99_11420	COG3258	Cytochrome c
H9J99_11425	COG2995	paraquat-inducible protein a
H9J99_11430	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H9J99_11430	COG3008	intermembrane lipid transfer
H9J99_11440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
H9J99_11450	COG0463	Glycosyl transferase, family 2
H9J99_11465	COG4166	transmembrane transport
H9J99_11470	COG0284	orotidine-5'-phosphate decarboxylase activity
H9J99_11475	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H9J99_11480	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
H9J99_11490	COG0539	negative regulation of cytoplasmic translation
H9J99_11495	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
H9J99_11500	COG0616	signal peptide processing
H9J99_11505	COG1028	Short-chain dehydrogenase reductase Sdr
H9J99_11520	COG0587	DNA-directed DNA polymerase activity
H9J99_11525	COG0784	Response regulator, receiver
H9J99_11525	COG0835	chemotaxis
H9J99_11530	COG1940	carbohydrate kinase activity
H9J99_11535	COG0469	pyruvate kinase activity
H9J99_11540	COG4667	esterase of the alpha-beta hydrolase superfamily
H9J99_11555	COG0733	neurotransmitter:sodium symporter activity
H9J99_11570	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9J99_11570	COG1263	PTS System
H9J99_11575	COG0084	hydrolase, TatD family'
H9J99_11585	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H9J99_11590	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9J99_11620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9J99_11625	COG0416	fatty acid biosynthetic process
H9J99_11635	COG1399	metal-binding, possibly nucleic acid-binding protein
H9J99_11640	COG0424	maF-like protein
H9J99_11645	COG0564	pseudouridine synthase activity
H9J99_11650	COG1530	ribonuclease E activity
H9J99_11655	COG0659	secondary active sulfate transmembrane transporter activity
H9J99_11660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H9J99_11665	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H9J99_11675	COG0572	uridine kinase
H9J99_11680	COG0489	protein tyrosine kinase activity
H9J99_11685	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9J99_11685	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9J99_11695	COG2186	Transcriptional regulator
H9J99_11700	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H9J99_11705	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H9J99_11710	COG3012	SEC-C Motif Domain Protein
H9J99_11710	COG3318	Belongs to the UPF0149 family
H9J99_11715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9J99_11735	COG4120	Belongs to the binding-protein-dependent transport system permease family
H9J99_11745	COG3092	negative regulation of chromosome organization
H9J99_11750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9J99_11755	COG0280	phosphate acetyltransferase
H9J99_11755	COG0857	belongs to the CobB CobQ family
H9J99_11760	COG3174	membrane
H9J99_11770	COG0435	Glutathione S-transferase
H9J99_11780	COG0444	Belongs to the ABC transporter superfamily
H9J99_11785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9J99_11790	COG0601	transmembrane transport
H9J99_11800	COG0314	molybdopterin synthase activity
H9J99_11805	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
H9J99_11810	COG0315	cyclic pyranopterin monophosphate synthase activity
H9J99_11815	COG0521	Mo-molybdopterin cofactor biosynthetic process
H9J99_11820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H9J99_11825	COG0391	Required for morphogenesis under gluconeogenic growth conditions
H9J99_11830	COG2198	Histidine kinase
H9J99_11835	COG2204	response regulator
H9J99_11840	COG0556	nucleotide-excision repair
H9J99_11850	COG4657	Part of a membrane complex involved in electron transport
H9J99_11855	COG2878	Part of a membrane complex involved in electron transport
H9J99_11860	COG4656	Part of a membrane complex involved in electron transport
H9J99_11865	COG4658	electron transport chain
H9J99_11870	COG4659	FMN binding
H9J99_11875	COG4660	Part of a membrane complex involved in electron transport
H9J99_11880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9J99_11885	COG0346	lactoylglutathione lyase activity
H9J99_11895	COG2885	chlorophyll binding
H9J99_11900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9J99_11905	COG2056	Na+-H+ antiporter family
H9J99_11915	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H9J99_11935	COG1454	alcohol dehydrogenase
H9J99_11935	COG1012	belongs to the aldehyde dehydrogenase family
H9J99_11940	COG2095	MarC family integral membrane protein
H9J99_11945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9J99_11950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9J99_11955	COG1757	Na H antiporter
H9J99_11970	COG3081	Nucleoid-associated protein
H9J99_11975	COG3082	Protein of unknown function (DUF1414)
H9J99_11980	COG3083	sulfuric ester hydrolase activity
H9J99_11990	COG0123	including yeast histone deacetylase and acetoin utilization protein
H9J99_12005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9J99_12015	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9J99_12015	COG1902	pentaerythritol trinitrate reductase activity
H9J99_12020	COG0616	signal peptide processing
H9J99_12025	COG0252	asparaginase activity
H9J99_12030	COG3139	Protein of unknown function (DUF1315)
H9J99_12040	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9J99_12045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9J99_12050	COG0676	glucose-6-phosphate 1-epimerase activity
H9J99_12060	COG2226	methyltransferase
H9J99_12075	COG1785	Belongs to the alkaline phosphatase family
H9J99_12085	COG0346	lactoylglutathione lyase activity
H9J99_12090	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H9J99_12095	COG0668	transmembrane transport
H9J99_12100	COG2983	Belongs to the UPF0260 family
H9J99_12105	COG2261	transglycosylase associated protein
H9J99_12120	COG3681	Belongs to the UPF0597 family
H9J99_12125	COG0251	oxidation-reduction process
H9J99_12130	COG0814	amino acid
H9J99_12135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9J99_12140	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H9J99_12145	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H9J99_12155	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9J99_12160	COG2832	Protein of unknown function (DUF454)
H9J99_12165	COG0745	RESPONSE REGULATOR receiver
H9J99_12170	COG0583	DNA-binding transcription factor activity
H9J99_12175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H9J99_12180	COG1286	toxin biosynthetic process
H9J99_12185	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
H9J99_12190	COG0285	dihydrofolate synthase activity
H9J99_12195	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9J99_12200	COG0101	tRNA pseudouridine synthase activity
H9J99_12210	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9J99_12215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9J99_12220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9J99_12230	COG0431	NADPH-dependent FMN reductase
H9J99_12240	COG3101	peptidyl-lysine hydroxylation
H9J99_12245	COG2860	membrane
H9J99_12250	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H9J99_12255	COG2890	protein-(glutamine-N5) methyltransferase activity
H9J99_12260	COG2840	Smr protein MutS2
H9J99_12265	COG2062	phosphohistidine phosphatase, SixA
H9J99_12280	COG1024	Enoyl-CoA hydratase
H9J99_12280	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9J99_12285	COG0183	Belongs to the thiolase family
H9J99_12300	COG2067	long-chain fatty acid transport protein
H9J99_12315	COG2853	Lipoprotein
H9J99_12330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9J99_12335	COG1138	Cytochrome C-type biogenesis protein
H9J99_12340	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
H9J99_12345	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9J99_12350	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9J99_12355	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
H9J99_12360	COG4133	protoheme IX ABC transporter activity
H9J99_12370	COG0835	chemotaxis
H9J99_12380	COG1192	Involved in chromosome partitioning
H9J99_12385	COG2201	protein-glutamate methylesterase activity
H9J99_12390	COG2198	Histidine kinase
H9J99_12390	COG0784	Response regulator, receiver
H9J99_12390	COG0643	Histidine kinase
H9J99_12395	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H9J99_12445	COG0596	Alpha beta hydrolase
H9J99_12480	COG1278	Cold shock
H9J99_12500	COG2826	transposase and inactivated derivatives, IS30 family
H9J99_12555	COG1684	flagellar biosynthetic protein fliR
H9J99_12560	COG1987	bacterial-type flagellum assembly
H9J99_12610	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H9J99_12620	COG1677	Flagellar hook-basal body complex protein FliE
H9J99_12640	COG1516	flagellar protein fliS
H9J99_12650	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H9J99_12655	COG1334	flagellar protein FlaG
H9J99_12660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9J99_12665	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9J99_12670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9J99_12675	COG2837	iron assimilation
H9J99_12700	COG1393	Belongs to the ArsC family
H9J99_12705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9J99_12720	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H9J99_12725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9J99_12730	COG2716	regulation of RNA biosynthetic process
H9J99_12735	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9J99_12750	COG4783	chaperone-mediated protein folding
H9J99_12755	COG1393	Belongs to the ArsC family
H9J99_12775	COG2233	PERMEase
H9J99_12780	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
H9J99_12785	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H9J99_12790	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9J99_12795	COG0121	glutamine amidotransferase
H9J99_12800	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H9J99_12805	COG1960	acyl-CoA dehydrogenase activity
H9J99_12820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H9J99_12825	COG0328	RNA-DNA hybrid ribonuclease activity
H9J99_12830	COG2226	methyltransferase
H9J99_12835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9J99_12840	COG1388	LysM domain
H9J99_12840	COG0741	lytic transglycosylase activity
H9J99_12850	COG3021	interspecies interaction between organisms
H9J99_12855	COG0347	Belongs to the P(II) protein family
H9J99_12865	COG0037	tRNA processing
H9J99_12870	COG0825	malonyl-CoA metabolic process
H9J99_12875	COG0587	DNA-directed DNA polymerase activity
H9J99_12880	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9J99_12885	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9J99_12890	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9J99_12895	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9J99_12900	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9J99_12905	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
H9J99_12915	COG0750	zinc metalloprotease
H9J99_12920	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H9J99_12925	COG0575	Belongs to the CDS family
H9J99_12930	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9J99_12935	COG0233	cytoplasmic translational termination
H9J99_12945	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9J99_12950	COG0052	Belongs to the universal ribosomal protein uS2 family
H9J99_12955	COG0024	Methionine aminopeptidase
H9J99_12960	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
H9J99_12970	COG0564	pseudouridine synthase activity
H9J99_12975	COG3098	single-species biofilm formation
H9J99_13000	COG1671	Belongs to the UPF0178 family
H9J99_13005	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
H9J99_13015	COG0254	rRNA binding
H9J99_13020	COG1720	tRNA m6t6A37 methyltransferase activity
H9J99_13025	COG0442	prolyl-tRNA aminoacylation
H9J99_13045	COG0733	neurotransmitter:sodium symporter activity
H9J99_13060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9J99_13065	COG0514	ATP-dependent DNA helicase (RecQ)
H9J99_13070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9J99_13085	COG1477	protein flavinylation
H9J99_13090	COG2871	sodium ion transport
H9J99_13095	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H9J99_13100	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H9J99_13105	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H9J99_13110	COG1805	sodium ion transport
H9J99_13115	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
H9J99_13120	COG0271	Belongs to the BolA IbaG family
H9J99_13125	COG2813	Specifically methylates the guanine in position
H9J99_13130	COG3056	Lipoprotein
H9J99_13150	COG1595	DNA-templated transcription, initiation
H9J99_13165	COG3248	Nucleoside-binding outer membrane protein
H9J99_13170	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H9J99_13175	COG0693	protein deglycase activity
H9J99_13180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9J99_13190	COG2166	iron-sulfur cluster assembly
H9J99_13195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9J99_13200	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H9J99_13210	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H9J99_13210	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H9J99_13230	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H9J99_13235	COG1074	ATP-dependent DNA helicase activity
H9J99_13240	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H9J99_13260	COG3141	response to X-ray
H9J99_13265	COG2171	N-acyltransferase activity
H9J99_13270	COG0584	glycerophosphoryl diester phosphodiesterase
H9J99_13275	COG2271	Major facilitator Superfamily
H9J99_13280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H9J99_13285	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H9J99_13290	COG1349	DNA-binding transcription factor activity
H9J99_13295	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H9J99_13300	COG0598	Magnesium transport protein CorA
H9J99_13320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9J99_13325	COG1609	Transcriptional regulator
H9J99_13345	COG2017	converts alpha-aldose to the beta-anomer
H9J99_13350	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H9J99_13360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9J99_13365	COG1609	Transcriptional regulator
H9J99_13370	COG3250	beta-galactosidase activity
H9J99_13375	COG2731	YhcH YjgK YiaL family protein
H9J99_13380	COG0531	amino acid
H9J99_13385	COG0583	DNA-binding transcription factor activity
H9J99_13445	COG4964	Belongs to the GSP D family
H9J99_13470	COG2169	Transcriptional regulator
H9J99_13475	COG1022	Amp-dependent synthetase and ligase
H9J99_13485	COG0583	DNA-binding transcription factor activity
H9J99_13490	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9J99_13495	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
H9J99_13505	COG0560	Phosphoserine phosphatase
H9J99_13515	COG0813	purine-nucleoside phosphorylase activity
H9J99_13520	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
H9J99_13525	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
H9J99_13530	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
H9J99_13535	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9J99_13540	COG0084	hydrolase, TatD family'
H9J99_13550	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H9J99_13570	COG3153	acetyltransferase
H9J99_13575	COG3154	lipid carrier protein
H9J99_13585	COG0826	peptidase U32
H9J99_13590	COG0826	peptidase U32
H9J99_13595	COG0534	Mate efflux family protein
H9J99_13610	COG1185	polyribonucleotide nucleotidyltransferase activity
H9J99_13615	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9J99_13620	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H9J99_13625	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H9J99_13630	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H9J99_13635	COG0195	Participates in both transcription termination and antitermination
H9J99_13640	COG0779	Required for maturation of 30S ribosomal subunits
H9J99_13655	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9J99_13660	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9J99_13665	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H9J99_13670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9J99_13675	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H9J99_13680	COG1534	Rna-binding protein
H9J99_13685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9J99_13690	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H9J99_13695	COG2027	D-alanyl-D-alanine carboxypeptidase
H9J99_13705	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9J99_13710	COG0739	heme binding
H9J99_13715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9J99_13725	COG0316	Belongs to the HesB IscA family
H9J99_13730	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
H9J99_13740	COG0628	permease
H9J99_13745	COG2813	Specifically methylates the guanine in position
H9J99_13750	COG2198	Histidine kinase
H9J99_13750	COG2205	protein histidine kinase activity
H9J99_13750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9J99_13750	COG0784	Response regulator, receiver
H9J99_13755	COG0747	negative chemotaxis
H9J99_13765	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9J99_13770	COG0444	Belongs to the ABC transporter superfamily
H9J99_13775	COG4608	Belongs to the ABC transporter superfamily
H9J99_13785	COG2971	BadF BadG BcrA BcrD
H9J99_13800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9J99_13805	COG3842	ATPase activity
H9J99_13815	COG1840	ABC-type Fe3 transport system, periplasmic component
H9J99_13820	COG0004	ammonium transporteR
H9J99_13830	COG3112	Uncharacterised protein family (UPF0231)
H9J99_13835	COG1049	propionate catabolic process, 2-methylcitrate cycle
H9J99_13840	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9J99_13845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9J99_13895	COG1643	Atp-dependent helicase
H9J99_13900	COG1489	DNA binding
H9J99_13910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9J99_13920	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9J99_13925	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H9J99_13930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H9J99_13935	COG1560	Kdo2-lipid A biosynthetic process
H9J99_13940	COG0842	Transport permease protein
H9J99_13945	COG1131	(ABC) transporter
H9J99_13950	COG0659	secondary active sulfate transmembrane transporter activity
H9J99_13955	COG0288	reversible hydration of carbon dioxide
H9J99_13970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9J99_13975	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9J99_13980	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H9J99_13985	COG2186	Transcriptional regulator
H9J99_13995	COG0157	Belongs to the NadC ModD family
H9J99_14005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9J99_14010	COG1459	type II secretion system
H9J99_14020	COG0237	dephospho-CoA kinase activity
H9J99_14025	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
H9J99_14030	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H9J99_14035	COG0335	large ribosomal subunit rRNA binding
H9J99_14040	COG0336	Belongs to the RNA methyltransferase TrmD family
H9J99_14045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9J99_14050	COG0228	four-way junction DNA binding
H9J99_14055	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9J99_14060	COG4137	Cytochrome C assembly protein
H9J99_14065	COG4536	flavin adenine dinucleotide binding
H9J99_14070	COG1854	S-ribosylhomocysteine lyase activity
H9J99_14080	COG2918	glutathione biosynthetic process
H9J99_14085	COG0612	Peptidase, M16
H9J99_14090	COG1238	metal cluster binding
H9J99_14105	COG5016	pyruvate
H9J99_14105	COG0511	ligase activity, forming carbon-carbon bonds
H9J99_14110	COG3630	sodium ion export across plasma membrane
H9J99_14170	COG0527	aspartate kinase activity
H9J99_14175	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
H9J99_14180	COG2137	regulation of response to DNA damage stimulus
H9J99_14185	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9J99_14190	COG1546	Belongs to the CinA family
H9J99_14195	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H9J99_14200	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9J99_14210	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H9J99_14215	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H9J99_14220	COG0585	pseudouridine synthase activity
H9J99_14225	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9J99_14230	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H9J99_14235	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H9J99_14240	COG0148	phosphopyruvate hydratase activity
H9J99_14245	COG0504	CTP synthase activity
H9J99_14250	COG3956	TIGRFAM MazG family protein
H9J99_14255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9J99_14260	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9J99_14270	COG0736	holo-[acyl-carrier-protein] synthase activity
H9J99_14275	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H9J99_14280	COG1381	Involved in DNA repair and RecF pathway recombination
H9J99_14285	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9J99_14290	COG0571	ribonuclease III activity
H9J99_14300	COG0481	GTPase activity
H9J99_14305	COG3086	response to oxidative stress
H9J99_14315	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
H9J99_14320	COG1595	DNA-templated transcription, initiation
H9J99_14325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H9J99_14330	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H9J99_14335	COG0354	folic acid binding
H9J99_14350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9J99_14355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9J99_14360	COG3079	Belongs to the UPF0149 family
H9J99_14365	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
H9J99_14375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9J99_14380	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H9J99_14385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9J99_14395	COG0583	DNA-binding transcription factor activity
H9J99_14405	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H9J99_14415	COG0668	transmembrane transport
H9J99_14420	COG0191	fructose-bisphosphate aldolase activity
H9J99_14425	COG0126	phosphoglycerate kinase activity
H9J99_14430	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H9J99_14435	COG4771	TonB-dependent receptor
H9J99_14440	COG0583	DNA-binding transcription factor activity
H9J99_14445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H9J99_14450	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H9J99_14460	COG3091	SprT-like family
H9J99_14465	COG2356	endonuclease I
H9J99_14470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9J99_14475	COG0189	ligase activity
H9J99_14480	COG1678	Uncharacterized ACR, COG1678
H9J99_14485	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H9J99_14500	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H9J99_14505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H9J99_14510	COG0762	integral membrane protein
H9J99_14515	COG1872	DUF167
H9J99_14525	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H9J99_14530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H9J99_14535	COG2066	Belongs to the glutaminase family
H9J99_14545	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H9J99_14555	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
H9J99_14560	COG0741	lytic transglycosylase activity
H9J99_14630	COG1012	belongs to the aldehyde dehydrogenase family
H9J99_14675	COG3437	response regulator, receiver
H9J99_14685	COG3394	polysaccharide catabolic process
H9J99_14690	COG1486	melibiose metabolic process
H9J99_14695	COG1447	Phosphotransferase system cellobiose-specific component IIA
H9J99_14700	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9J99_14705	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
H9J99_14710	COG0726	polysaccharide deacetylase
H9J99_14745	COG1061	Type III restriction enzyme res subunit
H9J99_14850	COG1028	Short-chain dehydrogenase reductase Sdr
H9J99_14865	COG0795	lipopolysaccharide-transporting ATPase activity
H9J99_14875	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9J99_14880	COG2927	DNA polymerase III (CHI subunit)
H9J99_14885	COG0525	valine-tRNA ligase activity
H9J99_14930	COG2235	arginine
H9J99_14935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9J99_14945	COG0540	Belongs to the ATCase OTCase family
H9J99_14950	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
H9J99_14955	COG0251	oxidation-reduction process
H9J99_14960	COG0204	Acyl-transferase
H9J99_14965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9J99_14970	COG5007	Belongs to the BolA IbaG family
H9J99_14980	COG2854	intermembrane phospholipid transfer
H9J99_14985	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H9J99_14990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9J99_14995	COG1127	ABC transporter
H9J99_15005	COG0517	IMP dehydrogenase activity
H9J99_15005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H9J99_15015	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H9J99_15020	COG1137	ATPase activity
H9J99_15030	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H9J99_15035	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9J99_15040	COG1660	Displays ATPase and GTPase activities
H9J99_15045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9J99_15050	COG2239	Acts as a magnesium transporter
H9J99_15055	COG0312	modulator of DNA gyrase
H9J99_15060	COG3028	Belongs to the UPF0307 family
H9J99_15065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9J99_15070	COG0564	pseudouridine synthase activity
H9J99_15080	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9J99_15085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H9J99_15095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9J99_15100	COG3164	Protein of unknown function
H9J99_15110	COG0424	maF-like protein
H9J99_15115	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H9J99_15120	COG1792	Involved in formation and maintenance of cell shape
H9J99_15125	COG1077	Cell shape determining protein MreB Mrl
H9J99_15170	COG1459	type II secretion system
H9J99_15175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9J99_15185	COG3409	Peptidoglycan-binding domain 1 protein
H9J99_15185	COG3267	Type II secretory pathway component ExeA
H9J99_15210	COG2199	diguanylate cyclase activity
H9J99_15210	COG2200	EAL domain
H9J99_15215	COG0629	single-stranded DNA binding
H9J99_15230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H9J99_15245	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H9J99_15250	COG0527	aspartate kinase activity
H9J99_15255	COG0646	methionine synthase
H9J99_15255	COG1410	methionine synthase
H9J99_15330	COG0175	sulfate reduction
H9J99_15335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9J99_15340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H9J99_15360	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9J99_15365	COG0735	belongs to the Fur family
H9J99_15375	COG0166	Belongs to the GPI family
H9J99_15380	COG0432	Pfam Uncharacterised protein family UPF0047
H9J99_15390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9J99_15405	COG0359	binds to the 23S rRNA
H9J99_15415	COG2965	DNA replication, synthesis of RNA primer
H9J99_15420	COG0360	Binds together with S18 to 16S ribosomal RNA
H9J99_15425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H9J99_15430	COG0338	D12 class N6 adenine-specific DNA methyltransferase
H9J99_15440	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
H9J99_15445	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H9J99_15475	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
H9J99_15485	COG0678	peroxiredoxin activity
H9J99_15485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H9J99_15495	COG0165	Argininosuccinate lyase
H9J99_15495	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
H9J99_15500	COG0137	argininosuccinate synthase activity
H9J99_15505	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H9J99_15510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H9J99_15515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9J99_15520	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H9J99_15530	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9J99_15535	COG0460	homoserine dehydrogenase
H9J99_15535	COG0527	aspartate kinase activity
H9J99_15540	COG0626	cystathionine gamma-synthase activity
H9J99_15550	COG0281	malic enzyme
H9J99_15560	COG2906	2 iron, 2 sulfur cluster binding
H9J99_15565	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9J99_15570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9J99_15575	COG0049	tRNA binding
H9J99_15585	COG2168	tRNA wobble position uridine thiolation
H9J99_15590	COG2923	Belongs to the DsrF TusC family
H9J99_15595	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H9J99_15600	COG2964	Protein conserved in bacteria
H9J99_15605	COG0545	Peptidyl-prolyl cis-trans isomerase
H9J99_15615	COG2900	Belongs to the SlyX family
H9J99_15620	COG1446	asparaginase
H9J99_15625	COG1047	Peptidyl-prolyl cis-trans
H9J99_15640	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9J99_15645	COG0488	(ABC) transporter
H9J99_15655	COG0429	hydrolase of the alpha beta-hydrolase fold
H9J99_15660	COG3089	Belongs to the UPF0270 family
H9J99_15665	COG3954	Phosphoribulokinase
H9J99_15670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9J99_15680	COG1012	belongs to the aldehyde dehydrogenase family
H9J99_15690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9J99_15695	COG0512	Glutamine amidotransferase of anthranilate synthase
H9J99_15710	COG0180	Tryptophanyl-tRNA synthetase
H9J99_15715	COG0546	phosphoglycolate phosphatase activity
H9J99_15720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9J99_15725	COG0557	exoribonuclease II activity
H9J99_15730	COG1959	2 iron, 2 sulfur cluster binding
H9J99_15735	COG1017	nitric oxide dioxygenase activity
H9J99_15735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H9J99_15740	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
H9J99_15745	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H9J99_15750	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H9J99_15755	COG0330	HflC and HflK could
H9J99_15760	COG0330	HflC and HflK could
H9J99_15765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9J99_15775	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9J99_15780	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H9J99_15790	COG0802	atpase or kinase
H9J99_15795	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H9J99_15870	COG1162	GTPase activity
H9J99_15875	COG0688	phosphatidylethanolamine metabolic process
H9J99_15880	COG0471	metal ion transport
H9J99_15895	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H9J99_15900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9J99_15905	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H9J99_15910	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9J99_15915	COG1045	serine acetyltransferase
H9J99_15920	COG4942	peptidase
H9J99_15940	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H9J99_15945	COG1053	succinate dehydrogenase
H9J99_15950	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H9J99_15955	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
H9J99_15960	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
H9J99_15970	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9J99_15975	COG1509	lysine 2,3-aminomutase activity
H9J99_15980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9J99_15995	COG0459	protein refolding
H9J99_16005	COG0534	Mate efflux family protein
H9J99_16010	COG0205	6-phosphofructokinase activity
H9J99_16020	COG3678	ATP-independent chaperone mediated protein folding
H9J99_16025	COG0745	RESPONSE REGULATOR receiver
H9J99_16030	COG2205	protein histidine kinase activity
H9J99_16040	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H9J99_16045	COG3030	protein affecting phage T7 exclusion by the F plasmid
H9J99_16050	COG1027	Aspartate ammonia-lyase
H9J99_16055	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H9J99_16060	COG4232	protein-disulfide reductase activity
H9J99_16070	COG3263	regulation of cellular component size
H9J99_16080	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9J99_16100	COG2198	Histidine kinase
H9J99_16100	COG0784	Response regulator, receiver
H9J99_16100	COG2205	protein histidine kinase activity
H9J99_16105	COG2814	Major facilitator Superfamily
H9J99_16120	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9J99_16125	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H9J99_16130	COG0511	ligase activity, forming carbon-carbon bonds
H9J99_16135	COG0439	Biotin carboxylase
H9J99_16140	COG2264	protein methyltransferase activity
H9J99_16145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9J99_16150	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H9J99_16155	COG2814	Major facilitator Superfamily
H9J99_16160	COG0488	(ABC) transporter
H9J99_16165	COG3706	GGDEF domain
H9J99_16230	COG1982	Orn Lys Arg decarboxylase major
H9J99_16235	COG0531	amino acid
H9J99_16240	COG3710	Transcriptional regulator
H9J99_16245	COG0789	Transcriptional regulator
H9J99_16250	COG0138	bifunctional purine biosynthesis protein purh
H9J99_16255	COG0151	Belongs to the GarS family
H9J99_16270	COG1253	flavin adenine dinucleotide binding
H9J99_16280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9J99_16285	COG1573	uracil-dna glycosylase
H9J99_16290	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H9J99_16305	COG2816	NAD+ diphosphatase activity
H9J99_16310	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
H9J99_16315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9J99_16320	COG0085	RNA polymerase activity
H9J99_16325	COG0222	ribosome binding
H9J99_16330	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9J99_16335	COG0081	regulation of translation
H9J99_16340	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H9J99_16345	COG0250	Participates in transcription elongation, termination and antitermination
H9J99_16350	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9J99_16355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9J99_16390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H9J99_16400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9J99_16435	COG0596	Alpha beta hydrolase
H9J99_16475	COG1278	Cold shock
H9J99_16495	COG2826	transposase and inactivated derivatives, IS30 family
H9J99_16530	COG0456	acetyltransferase
H9J99_16530	COG1214	PFAM Peptidase M22, glycoprotease
H9J99_16545	COG3069	C4-dicarboxylate transmembrane transporter activity
H9J99_16550	COG1704	LemA family
H9J99_16555	COG0501	Belongs to the peptidase M48B family
H9J99_16580	COG0641	radical SAM
H9J99_16595	COG3111	PFAM Bacterial OB fold (BOF) protein
H9J99_16600	COG1597	lipid kinase activity
H9J99_16605	COG0583	DNA-binding transcription factor activity
H9J99_16640	COG0714	Associated with various cellular activities
H9J99_16645	COG0641	radical SAM
H9J99_16650	COG3119	arylsulfatase activity
H9J99_16665	COG3119	arylsulfatase activity
H9J99_16670	COG3119	arylsulfatase activity
H9J99_16675	COG0745	RESPONSE REGULATOR receiver
H9J99_16690	COG2198	Histidine kinase
H9J99_16690	COG2205	protein histidine kinase activity
H9J99_16690	COG0784	Response regulator, receiver
H9J99_16695	COG1879	ABC-type sugar transport system periplasmic component
H9J99_16700	COG1803	Methylglyoxal synthase
H9J99_16705	COG0210	DNA helicase
H9J99_16710	COG1289	transmembrane transporter activity
H9J99_16740	COG4771	TonB-dependent receptor
H9J99_16740	COG1629	transport
H9J99_16750	COG0789	Transcriptional regulator
H9J99_16755	COG4604	ABC transporter, ATP-binding protein
H9J99_16760	COG4605	iron ion homeostasis
H9J99_16765	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9J99_16770	COG4607	ABC-type enterochelin transport system periplasmic component
H9J99_16780	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
H9J99_16795	COG1609	Transcriptional regulator
H9J99_16800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9J99_16805	COG1879	ABC-type sugar transport system periplasmic component
H9J99_16810	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9J99_16815	COG1129	ABC transporter
H9J99_16820	COG1869	D-ribose catabolic process
H9J99_16825	COG5001	Diguanylate cyclase
H9J99_16830	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H9J99_16885	COG0784	Response regulator, receiver
H9J99_16885	COG2205	protein histidine kinase activity
H9J99_16895	COG3300	MHYT domain
H9J99_16895	COG5001	Diguanylate cyclase
H9J99_16905	COG0330	HflC and HflK could
H9J99_16920	COG0517	IMP dehydrogenase activity
H9J99_16920	COG4175	Glycine betaine
H9J99_16950	COG1012	belongs to the aldehyde dehydrogenase family
H9J99_16955	COG1309	transcriptional regulator
H9J99_16960	COG3706	GGDEF domain
H9J99_16965	COG1028	Short-chain dehydrogenase reductase Sdr
H9J99_16980	COG1024	Enoyl-CoA hydratase
H9J99_16985	COG1960	acyl-CoA dehydrogenase activity
H9J99_16995	COG0183	Belongs to the thiolase family
H9J99_17005	COG1960	acyl-CoA dehydrogenase activity
H9J99_17010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9J99_17015	COG1024	Enoyl-CoA hydratase
H9J99_17020	COG4770	biotin carboxylase activity
H9J99_17030	COG2205	protein histidine kinase activity
H9J99_17030	COG3437	response regulator, receiver
H9J99_17030	COG3850	Histidine kinase
H9J99_17030	COG4999	Histidine kinase
H9J99_17045	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
H9J99_17045	COG3264	Mechanosensitive ion channel
H9J99_17050	COG0110	maltose O-acetyltransferase activity
H9J99_17055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9J99_17060	COG1271	oxidase subunit
H9J99_17065	COG1294	oxidase, subunit
H9J99_17075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9J99_17080	COG0789	Transcriptional regulator
H9J99_17150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9J99_17170	COG3335	DDE superfamily endonuclease
H9J99_17285	COG0455	bacterial-type flagellum organization
H9J99_17330	COG2356	endonuclease I
H9J99_17425	COG0693	protein deglycase activity
H9J99_17445	COG1012	belongs to the aldehyde dehydrogenase family
H9J99_17455	COG2199	diguanylate cyclase activity
H9J99_17455	COG2200	EAL domain
H9J99_17455	COG2202	Pas domain
H9J99_17480	COG3385	transposase activity
H9J99_17485	COG0840	transmembrane signaling receptor activity
H9J99_17565	COG1484	DNA-dependent DNA replication
H9J99_17595	COG3852	Histidine kinase
H9J99_17605	COG0582	viral genome integration into host DNA
H9J99_17610	COG0516	GMP reductase activity
H9J99_17615	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H9J99_17615	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9J99_17630	COG4989	oxidoreductase activity
H9J99_17645	COG0038	chloride channel
H9J99_17655	COG1914	H( )-stimulated, divalent metal cation uptake system
H9J99_17660	COG0302	gtp cyclohydrolase
H9J99_17670	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9J99_17690	COG2897	thiosulfate sulfurtransferase activity
H9J99_17710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H9J99_17715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H9J99_17720	COG0840	transmembrane signaling receptor activity
H9J99_17725	COG2814	Major facilitator Superfamily
H9J99_17730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H9J99_17740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9J99_17750	COG0840	transmembrane signaling receptor activity
H9J99_17770	COG2195	Cleaves the N-terminal amino acid of tripeptides
H9J99_17785	COG2197	response regulator
H9J99_17790	COG3850	Histidine kinase
H9J99_17795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9J99_17805	COG0243	molybdopterin cofactor binding
H9J99_17815	COG3005	denitrification pathway
H9J99_17835	COG0183	Belongs to the thiolase family
H9J99_17850	COG1280	lysine exporter protein (LysE YggA)
H9J99_17860	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9J99_17865	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9J99_17890	COG1522	sequence-specific DNA binding
H9J99_17910	COG1566	PFAM secretion protein HlyD family protein
H9J99_17920	COG0784	Response regulator, receiver
H9J99_17920	COG2205	protein histidine kinase activity
H9J99_17925	COG1879	ABC-type sugar transport system periplasmic component
H9J99_17930	COG2827	Endonuclease containing a URI domain
H9J99_17935	COG3132	Protein of unknown function, DUF480
H9J99_17945	COG2926	Belongs to the UPF0265 family
H9J99_17950	COG0534	Mate efflux family protein
H9J99_17955	COG0673	inositol 2-dehydrogenase activity
H9J99_17980	COG0583	DNA-binding transcription factor activity
H9J99_17985	COG1522	sequence-specific DNA binding
H9J99_17990	COG0531	amino acid
H9J99_18005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9J99_18015	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H9J99_18020	COG0402	S-adenosylhomocysteine deaminase activity
H9J99_18030	COG1418	mRNA catabolic process
H9J99_18040	COG2814	Major facilitator Superfamily
H9J99_18050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H9J99_18070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9J99_18085	COG4221	oxidoreductase activity
H9J99_18090	COG0745	RESPONSE REGULATOR receiver
H9J99_18095	COG2205	protein histidine kinase activity
H9J99_18105	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9J99_18110	COG2194	sulfuric ester hydrolase activity
H9J99_18115	COG0673	inositol 2-dehydrogenase activity
H9J99_18150	COG4667	esterase of the alpha-beta hydrolase superfamily
H9J99_18155	COG1741	Belongs to the pirin family
H9J99_18160	COG1278	Cold shock
H9J99_18170	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H9J99_18185	COG1686	Belongs to the peptidase S11 family
H9J99_18190	COG0625	glutathione transferase activity
H9J99_18195	COG1621	beta-fructofuranosidase activity
H9J99_18200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9J99_18205	COG1263	PTS System
H9J99_18205	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9J99_18225	COG1028	Short-chain dehydrogenase reductase Sdr
H9J99_18240	COG3746	phosphate-selective porin O and P
H9J99_18260	COG2207	Transcriptional regulator
H9J99_18260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
H9J99_18265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9J99_18285	COG0513	Belongs to the DEAD box helicase family
H9J99_18295	COG0583	DNA-binding transcription factor activity
H9J99_18310	COG1902	pentaerythritol trinitrate reductase activity
H9J99_18315	COG1063	alcohol dehydrogenase
H9J99_18325	COG1028	Short-chain dehydrogenase reductase Sdr
H9J99_18335	COG3122	Protein conserved in bacteria
H9J99_18350	COG0583	DNA-binding transcription factor activity
H9J99_18355	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H9J99_18365	COG0252	asparaginase activity
H9J99_18370	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
H9J99_18375	COG0574	Belongs to the PEP-utilizing enzyme family
H9J99_18375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H9J99_18390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9J99_18410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9J99_18430	COG3706	GGDEF domain
H9J99_18450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H9J99_18480	COG3842	ATPase activity
H9J99_18525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9J99_18560	COG0583	DNA-binding transcription factor activity
H9J99_18570	COG4948	Mandelate Racemase Muconate Lactonizing
H9J99_18600	COG1342	Belongs to the UPF0251 family
H9J99_18605	COG3015	lipoprotein NlpE involved in copper resistance
H9J99_18610	COG3713	MltA-interacting MipA family protein
H9J99_18625	COG0583	DNA-binding transcription factor activity
H9J99_18650	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H9J99_18660	COG1335	isochorismatase
H9J99_18670	COG0753	catalase activity
H9J99_18680	COG1349	DNA-binding transcription factor activity
H9J99_18685	COG0346	lactoylglutathione lyase activity
H9J99_18705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9J99_18710	COG3537	Alpha-1,2-mannosidase
H9J99_18715	COG3537	Alpha-1,2-mannosidase
H9J99_18725	COG3537	Alpha-1,2-mannosidase
H9J99_18730	COG3537	Alpha-1,2-mannosidase
H9J99_18735	COG2070	2-Nitropropane dioxygenase
H9J99_18740	COG0737	Belongs to the 5'-nucleotidase family
H9J99_18750	COG1309	transcriptional regulator
H9J99_18785	COG0459	protein refolding
H9J99_18790	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H9J99_18795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9J99_18810	COG1304	FMN binding
H9J99_18830	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9J99_18845	COG1706	bacterial-type flagellum-dependent cell motility
H9J99_18850	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H9J99_18855	COG4786	Flagellar basal body rod
H9J99_18860	COG4787	bacterial-type flagellum-dependent cell motility
H9J99_18865	COG1749	Flagellar hook protein flgE
H9J99_18870	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H9J99_18875	COG1558	bacterial-type flagellum-dependent cell motility
H9J99_18880	COG1815	bacterial-type flagellum-dependent cell motility
H9J99_18900	COG0741	lytic transglycosylase activity
H9J99_18905	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H9J99_18925	COG1760	l-serine dehydratase
H9J99_18930	COG3104	oligopeptide transport
H9J99_18950	COG0583	DNA-binding transcription factor activity
H9J99_18960	COG2866	Carboxypeptidase
H9J99_18965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9J99_18975	COG2990	Protein conserved in bacteria
H9J99_19000	COG3842	ATPase activity
H9J99_19010	COG1840	ABC-type Fe3 transport system, periplasmic component
H9J99_19015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H9J99_19020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H9J99_19025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9J99_19030	COG1609	Transcriptional regulator
H9J99_19060	COG3240	lipase activity
H9J99_19065	COG2067	long-chain fatty acid transport protein
H9J99_19075	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
H9J99_19090	COG1011	Hydrolase
H9J99_19130	COG0110	maltose O-acetyltransferase activity
H9J99_19135	COG1765	OsmC-like protein
H9J99_19150	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9J99_19160	COG2189	Belongs to the N(4) N(6)-methyltransferase family
H9J99_19165	COG3421	Type III restriction
H9J99_19455	COG1765	OsmC-like protein
H9J99_19460	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9J99_19460	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9J99_19475	COG3046	protein related to deoxyribodipyrimidine photolyase
H9J99_19480	COG0415	Belongs to the DNA photolyase family
H9J99_19485	COG3706	GGDEF domain
H9J99_19500	COG0840	transmembrane signaling receptor activity
H9J99_19505	COG3706	GGDEF domain
H9J99_19520	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
H9J99_19535	COG3033	Beta-eliminating lyase
H9J99_19545	COG0579	oxidoreductase
H9J99_19565	COG2199	diguanylate cyclase activity
H9J99_19570	COG2204	response regulator
H9J99_19575	COG4191	Histidine kinase
H9J99_19610	COG0583	DNA-binding transcription factor activity
H9J99_19615	COG0189	ligase activity
H9J99_19620	COG4067	protein conserved in archaea
H9J99_19620	COG0189	ligase activity
H9J99_19630	COG1166	arginine decarboxylase activity
H9J99_19635	COG0010	Belongs to the arginase family
H9J99_19640	COG2814	Major facilitator Superfamily
H9J99_19645	COG1770	oligopeptidase
H9J99_19660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H9J99_19665	COG1121	(ABC) transporter
H9J99_19670	COG0803	Belongs to the bacterial solute-binding protein 9 family
H9J99_19710	COG0848	biopolymer transport protein
H9J99_19715	COG0811	peptide transport
H9J99_19720	COG0811	peptide transport
H9J99_19740	COG0745	RESPONSE REGULATOR receiver
H9J99_19745	COG0039	L-malate dehydrogenase activity
H9J99_19750	COG0584	glycerophosphoryl diester phosphodiesterase
H9J99_19760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9J99_19815	COG1901	pseudouridine methyltransferase
H9J99_19820	COG0312	modulator of DNA gyrase
H9J99_19825	COG0312	modulator of DNA gyrase
H9J99_19830	COG0351	phosphomethylpyrimidine kinase
H9J99_19835	COG1116	anion transmembrane transporter activity
H9J99_19840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9J99_19845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9J99_19850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H9J99_19855	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
H9J99_19860	COG0352	thiamine-phosphate diphosphorylase activity
H9J99_19870	COG0243	molybdopterin cofactor binding
H9J99_19875	COG3005	denitrification pathway
H9J99_19885	COG1028	Short-chain dehydrogenase reductase Sdr
H9J99_19900	COG0456	acetyltransferase
H9J99_19920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9J99_19925	COG1929	Belongs to the glycerate kinase type-1 family
H9J99_19930	COG2610	gluconate transmembrane transporter activity
H9J99_19935	COG3835	regulator
H9J99_19975	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
H9J99_19980	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
H9J99_19980	COG3408	Glycogen debranching enzyme
H9J99_20010	COG3047	cAMP biosynthetic process
H9J99_20015	COG1357	PFAM Pentapeptide repeats (8 copies)
H9J99_20050	COG2375	cellular response to nickel ion
H9J99_20055	COG0583	DNA-binding transcription factor activity
H9J99_20060	COG2162	N-hydroxyarylamine O-acetyltransferase activity
H9J99_20065	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H9J99_20080	COG2199	diguanylate cyclase activity
H9J99_20090	COG0561	phosphatase activity
H9J99_20095	COG0583	DNA-binding transcription factor activity
H9J99_20110	COG0564	pseudouridine synthase activity
H9J99_20115	COG0534	Mate efflux family protein
H9J99_20120	COG5001	Diguanylate cyclase
H9J99_20130	COG3123	guanosine phosphorylase activity
H9J99_20170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
H9J99_20180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9J99_20185	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H9J99_20195	COG2259	Doxx family
H9J99_20200	COG1741	Belongs to the pirin family
H9J99_20220	COG0363	glucosamine-6-phosphate deaminase activity
H9J99_20230	COG0786	glutamate:sodium symporter activity
H9J99_20235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9J99_20240	COG1131	(ABC) transporter
H9J99_20250	COG0786	glutamate:sodium symporter activity
H9J99_20275	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H9J99_20285	COG3279	Response regulator of the LytR AlgR family
H9J99_20290	COG3275	phosphorelay sensor kinase activity
H9J99_20310	COG1136	(ABC) transporter
H9J99_20320	COG0772	Belongs to the SEDS family
H9J99_20325	COG0217	transcriptional regulatory protein
H9J99_20355	COG0444	Belongs to the ABC transporter superfamily
H9J99_20360	COG4608	Belongs to the ABC transporter superfamily
H9J99_20385	COG1444	tRNA N-acetyltransferase activity
H9J99_20405	COG3340	Belongs to the peptidase S51 family
H9J99_20410	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H9J99_20415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9J99_20415	COG1263	PTS System
H9J99_20420	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
H9J99_20435	COG4166	transmembrane transport
H9J99_20485	COG0259	pyridoxamine-phosphate oxidase activity
H9J99_20510	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9J99_20585	COG0800	Aldolase
H9J99_20590	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9J99_20600	COG0246	Mannitol dehydrogenase
H9J99_20610	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H9J99_20620	COG2186	Transcriptional regulator
H9J99_20630	COG0513	Belongs to the DEAD box helicase family
H9J99_20635	COG2258	MOSC domain
H9J99_20650	COG1486	melibiose metabolic process
H9J99_20655	COG0583	DNA-binding transcription factor activity
H9J99_20670	COG1595	DNA-templated transcription, initiation
H9J99_20695	COG3634	alkyl hydroperoxide reductase activity
H9J99_20705	COG1846	Transcriptional regulator
H9J99_20710	COG1764	response to oxidative stress
H9J99_20735	COG2160	L-arabinose isomerase activity
H9J99_20750	COG1879	ABC-type sugar transport system periplasmic component
H9J99_20755	COG1129	ABC transporter
H9J99_20760	COG1172	Belongs to the binding-protein-dependent transport system permease family
H9J99_20765	COG0826	peptidase U32
H9J99_20790	COG1653	transport
H9J99_20795	COG0019	diaminopimelate decarboxylase activity
H9J99_20800	COG4264	IucA IucC family
H9J99_20825	COG4772	TonB-dependent receptor
H9J99_20830	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H9J99_20835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9J99_20840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9J99_20845	COG1120	ATPase activity
H9J99_20850	COG0840	transmembrane signaling receptor activity
H9J99_20855	COG0612	Peptidase, M16
H9J99_20865	COG0739	heme binding
H9J99_20890	COG4580	involved in the transport of maltose and maltodextrins
H9J99_20910	COG2356	endonuclease I
H9J99_20940	COG3423	Transcriptional regulator
H9J99_21040	COG5566	PFAM Mor transcription activator
H9J99_21070	COG0640	Transcriptional regulator
H9J99_21080	COG4373	Mu-like prophage FluMu protein gp28
H9J99_21085	COG4383	Mu-like prophage protein gp29
H9J99_21105	COG4388	Caudovirus prohead serine protease
H9J99_21115	COG4397	Mu-like prophage major head subunit gpT
H9J99_21125	COG4387	Mu-like prophage protein GP36
H9J99_21195	COG0531	amino acid
H9J99_21205	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
H9J99_21215	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
H9J99_21220	COG1162	GTPase activity
H9J99_21225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
H9J99_21225	COG1263	PTS System
H9J99_21235	COG1999	signal sequence binding
H9J99_21250	COG2909	trisaccharide binding
H9J99_21255	COG0058	SHG alpha-glucan phosphorylase activity
H9J99_21260	COG1640	4-alpha-glucanotransferase
H9J99_21265	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
H9J99_21270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9J99_21275	COG0366	Alpha amylase catalytic
H9J99_21290	COG3366	ferrous iron transmembrane transporter activity
H9J99_21295	COG0700	Nucleoside recognition
H9J99_21300	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9J99_21305	COG3339	Conserved Protein
H9J99_21310	COG1301	dicarboxylic acid transport
H9J99_21340	COG0583	DNA-binding transcription factor activity
H9J99_21365	COG2095	MarC family integral membrane protein
H9J99_21370	COG4667	esterase of the alpha-beta hydrolase superfamily
H9J99_21375	COG3397	chitin binding
H9J99_21385	COG1054	Belongs to the UPF0176 family
H9J99_21400	COG1686	Belongs to the peptidase S11 family
H9J99_21425	COG0583	DNA-binding transcription factor activity
H9J99_21430	COG4628	conserved protein (DUF2132)
H9J99_21440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H9J99_21450	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H9J99_21455	COG0628	permease
H9J99_21495	COG2814	Major facilitator Superfamily
H9J99_21505	COG0454	-acetyltransferase
H9J99_21515	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H9J99_21520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H9J99_21525	COG1882	Formate acetyltransferase
H9J99_21555	COG1360	Flagellar Motor Protein
H9J99_21560	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
H9J99_21565	COG1191	sigma factor activity
H9J99_21570	COG1580	Controls the rotational direction of flagella during chemotaxis
H9J99_21585	COG1516	flagellar protein fliS
H9J99_21590	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
H9J99_21610	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9J99_21625	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
H9J99_21635	COG1987	bacterial-type flagellum assembly
H9J99_21725	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9J99_21745	COG0346	lactoylglutathione lyase activity
H9J99_21770	COG0745	RESPONSE REGULATOR receiver
H9J99_21790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9J99_21800	COG0156	8-amino-7-oxononanoate synthase activity
H9J99_21805	COG1063	alcohol dehydrogenase
H9J99_21840	COG0668	transmembrane transport
H9J99_21850	COG1304	FMN binding
H9J99_21855	COG1620	l-lactate permease
H9J99_21860	COG0583	DNA-binding transcription factor activity
H9J99_21865	COG1505	serine-type exopeptidase activity
H9J99_21870	COG4172	Belongs to the ABC transporter superfamily
H9J99_21880	COG1067	ATP-dependent peptidase activity
H9J99_21905	COG1247	-acetyltransferase
H9J99_21910	COG0437	4 iron, 4 sulfur cluster binding
H9J99_21915	COG0348	domain, Protein
H9J99_21930	COG1122	ATPase activity
H9J99_21935	COG4720	Psort location CytoplasmicMembrane, score
H9J99_21940	COG1566	PFAM secretion protein HlyD family protein
H9J99_21950	COG3706	GGDEF domain
H9J99_21965	COG0813	purine-nucleoside phosphorylase activity
H9J99_21970	COG3272	Protein of unknown function (DUF1722)
H9J99_21975	COG0789	Transcriptional regulator
H9J99_21980	COG0415	Belongs to the DNA photolyase family
H9J99_21985	COG1376	ErfK ybiS ycfS ynhG family protein
H9J99_21985	COG1388	LysM domain
H9J99_21995	COG0513	Belongs to the DEAD box helicase family
H9J99_22000	COG1770	oligopeptidase
H9J99_22005	COG4771	TonB-dependent receptor
H9J99_22035	COG0573	inorganic phosphate transmembrane transporter activity
H9J99_22040	COG0581	inorganic phosphate transmembrane transporter activity
H9J99_22045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9J99_22080	COG0714	Associated with various cellular activities
H9J99_22085	COG0840	transmembrane signaling receptor activity
H9J99_22145	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H9J99_22150	COG1120	ATPase activity
H9J99_22155	COG4774	siderophore transport
H9J99_22160	COG1132	(ABC) transporter
H9J99_22175	COG0569	domain protein
H9J99_22180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H9J99_22190	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
H9J99_22195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H9J99_22210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9J99_22210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9J99_22210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9J99_22215	COG2207	Transcriptional regulator
H9J99_22225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9J99_22230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9J99_22235	COG2084	Dehydrogenase
H9J99_22240	COG0753	catalase activity
H9J99_22250	COG2130	NADP-dependent
H9J99_22255	COG1309	transcriptional regulator
H9J99_22260	COG3097	Belongs to the UPF0267 family
H9J99_22320	COG3842	ATPase activity
H9J99_22330	COG1175	transmembrane transport
H9J99_22335	COG3833	ABC-type maltose transport systems, permease component
H9J99_22365	COG2354	Protein conserved in bacteria
H9J99_22370	COG0418	dihydroorotase activity
H9J99_22375	COG0401	homolog of Blt101
H9J99_22380	COG0633	Ferredoxin
H9J99_22380	COG3217	Mosc domain protein beta barrel domain protein
H9J99_22380	COG0633	Ferredoxin
H9J99_22380	COG3217	Mosc domain protein beta barrel domain protein
H9J99_22385	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H9J99_22390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H9J99_22430	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
H9J99_22435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H9J99_22445	COG0848	biopolymer transport protein
H9J99_22450	COG0811	peptide transport
H9J99_22455	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
H9J99_22465	COG3721	Heme iron utilization protein
H9J99_22470	COG0748	coenzyme F420 binding
H9J99_22480	COG0784	Response regulator, receiver
H9J99_22480	COG0835	chemotaxis
H9J99_22485	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9J99_22520	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
H9J99_22525	COG0783	Belongs to the Dps family
H9J99_22530	COG0583	DNA-binding transcription factor activity
H9J99_22545	COG4934	collagen metabolic process
H9J99_22555	COG0366	Alpha amylase catalytic
H9J99_22575	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9J99_22580	COG0589	response to stress
H9J99_22585	COG0488	(ABC) transporter
H9J99_22590	COG1505	serine-type exopeptidase activity
H9J99_22605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9J99_22615	COG2067	long-chain fatty acid transport protein
H9J99_22625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9J99_22655	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9J99_22675	COG3383	formate dehydrogenase (NAD+) activity
H9J99_22690	COG0842	Transport permease protein
H9J99_22695	COG1131	(ABC) transporter
H9J99_22710	COG2706	6-phosphogluconolactonase activity
H9J99_22720	COG1881	PFAM PEBP family protein
H9J99_22730	COG0798	PFAM Bile acid sodium symporter
H9J99_22745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9J99_22750	COG2213	PTS system mannitol-specific
H9J99_22755	COG1063	alcohol dehydrogenase
H9J99_22765	COG1072	(Pantothenic acid kinase))
H9J99_22770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
H9J99_22790	COG0814	amino acid
H9J99_22800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H9J99_22830	COG3314	Sporulation integral membrane protein YlbJ
H9J99_22850	COG0739	heme binding
H9J99_22870	COG0583	DNA-binding transcription factor activity
H9J99_22875	COG2814	Major facilitator Superfamily
H9J99_22890	COG0697	spore germination
H9J99_22895	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H9J99_22920	COG2207	Transcriptional regulator
H9J99_22940	COG1045	serine acetyltransferase
H9J99_22945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9J99_22950	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9J99_22960	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
H9J99_22985	COG1612	heme a metabolic process
H9J99_22990	COG0109	protoheme IX farnesyltransferase activity
H9J99_22995	COG0545	Peptidyl-prolyl cis-trans isomerase
H9J99_23025	COG1278	Cold shock
H9J99_23030	COG3036	rescue of stalled ribosome
H9J99_23040	COG2199	diguanylate cyclase activity
H9J99_23060	COG1136	(ABC) transporter
H9J99_23060	COG0577	efflux transmembrane transporter activity
H9J99_23070	COG0840	transmembrane signaling receptor activity
H9J99_23075	COG0783	Belongs to the Dps family
H9J99_23085	COG2133	pyrroloquinoline quinone binding
H9J99_23090	COG1454	alcohol dehydrogenase
H9J99_23095	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H9J99_23125	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9J99_23130	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9J99_23135	COG3186	Phenylalanine-4-hydroxylase
H9J99_23140	COG2154	pterin-4-alpha-carbinolamine dehydratase
H9J99_23160	COG3530	Putative quorum-sensing-regulated virulence factor
H9J99_23165	COG0513	Belongs to the DEAD box helicase family
H9J99_23170	COG4628	conserved protein (DUF2132)
H9J99_23175	COG0133	tryptophan synthase activity
H9J99_23185	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H9J99_23195	COG0523	cobalamin synthesis protein
H9J99_23200	COG0513	Belongs to the DEAD box helicase family
H9J99_23220	COG2200	EAL domain
H9J99_23225	COG1119	ATPase activity
H9J99_23250	COG0641	radical SAM
H9J99_23275	COG0582	viral genome integration into host DNA
H9J99_23330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H9J99_23345	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
H9J99_23350	COG0513	Belongs to the DEAD box helicase family
H9J99_23355	COG5001	Diguanylate cyclase
H9J99_23360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H9J99_23375	COG5413	integral membrane protein
H9J99_23385	COG1024	Enoyl-CoA hydratase
H9J99_23390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9J99_23395	COG1960	acyl-CoA dehydrogenase activity
H9J99_23405	COG0183	Belongs to the thiolase family
H9J99_23420	COG1024	Enoyl-CoA hydratase
H9J99_23425	COG1024	Enoyl-CoA hydratase
H9J99_23435	COG1028	Short-chain dehydrogenase reductase Sdr
H9J99_23440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9J99_23445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9J99_23450	COG1845	cytochrome c oxidase, subunit III
H9J99_23455	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H9J99_23460	COG0109	protoheme IX farnesyltransferase activity
H9J99_23475	COG1902	pentaerythritol trinitrate reductase activity
H9J99_23485	COG1126	abc transporter atp-binding protein
H9J99_23490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9J99_23495	COG4215	(ABC) transporter
H9J99_23500	COG4160	amino acid transport
H9J99_23515	COG0625	glutathione transferase activity
H9J99_23550	COG0443	Heat shock 70 kDa protein
H9J99_23555	COG2847	Copper chaperone PCu(A)C
H9J99_23580	COG0745	RESPONSE REGULATOR receiver
H9J99_23595	COG1785	Belongs to the alkaline phosphatase family
H9J99_23620	COG0814	amino acid
H9J99_23630	COG0243	molybdopterin cofactor binding
H9J99_23635	COG1648	precorrin-2 dehydrogenase activity
H9J99_23635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H9J99_23650	COG3707	response regulator
H9J99_23655	COG1116	anion transmembrane transporter activity
H9J99_23655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9J99_23660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9J99_23665	COG1116	anion transmembrane transporter activity
H9J99_23670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9J99_23670	COG2146	nitrite reductase [NAD(P)H] activity
H9J99_23720	COG2815	serine threonine protein kinase
H9J99_23720	COG0515	serine threonine protein kinase
H9J99_23825	COG0420	3'-5' exonuclease activity
H9J99_23830	COG0419	ATPase involved in DNA repair
H9J99_23850	COG3040	lipid binding
H9J99_23860	COG2814	Major facilitator Superfamily
H9J99_23870	COG1288	antiporter activity
H9J99_23880	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
H9J99_23895	COG2425	protein containing a von Willebrand factor type A (vWA) domain
H9J99_23910	COG0583	DNA-binding transcription factor activity
H9J99_23915	COG0277	FAD linked oxidase domain protein
H9J99_23930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9J99_23985	COG0840	transmembrane signaling receptor activity
H9J99_24025	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H9J99_24025	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9J99_24060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9J99_24065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9J99_24075	COG2116	formate transmembrane transporter activity
H9J99_24095	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
H9J99_24125	COG0534	Mate efflux family protein
H9J99_24140	COG3118	belongs to the thioredoxin family
H9J99_24145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9J99_24170	COG2271	Major facilitator Superfamily
H9J99_24175	COG3851	Histidine kinase
H9J99_24180	COG2197	response regulator
H9J99_24190	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H9J99_24195	COG0583	DNA-binding transcription factor activity
H9J99_24200	COG0243	molybdopterin cofactor binding
H9J99_24230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9J99_24245	COG1328	CTP reductase activity
H9J99_24250	COG0602	queuosine metabolic process
H9J99_24255	COG0534	Mate efflux family protein
H9J99_24270	COG4067	protein conserved in archaea
H9J99_24270	COG0189	ligase activity
H9J99_24280	COG3111	PFAM Bacterial OB fold (BOF) protein
H9J99_24285	COG1492	cobalamin metabolic process
H9J99_24290	COG0725	ABC transporter, periplasmic molybdate-binding protein
H9J99_24295	COG4149	molybdate abc transporter
H9J99_24300	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H9J99_24310	COG2203	Gaf domain
H9J99_24310	COG4251	negative regulation of phosphorylation
H9J99_24310	COG5001	Diguanylate cyclase
H9J99_24310	COG3706	GGDEF domain
H9J99_24335	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H9J99_24340	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
H9J99_24370	COG3140	Belongs to the UPF0181 family
H9J99_24375	COG0589	response to stress
H9J99_24390	COG0023	Translation Initiation Factor
H9J99_24400	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9J99_24410	COG1042	CoA-binding domain protein
H9J99_24410	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H9J99_24410	COG0045	succinate-CoA ligase (ADP-forming) activity
H9J99_24415	COG0583	DNA-binding transcription factor activity
H9J99_24420	COG1629	transport
H9J99_24420	COG4771	TonB-dependent receptor
H9J99_24425	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H9J99_24430	COG5001	Diguanylate cyclase
H9J99_24430	COG3447	MASE1 domain protein
H9J99_24430	COG5002	protein histidine kinase activity
H9J99_24435	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H9J99_24440	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H9J99_24445	COG1984	allophanate hydrolase subunit 2
H9J99_24455	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H9J99_24460	COG4181	ATPase activity
H9J99_24470	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H9J99_24475	COG5001	Diguanylate cyclase
H9J99_24475	COG3300	MHYT domain
H9J99_24485	COG0484	heat shock protein binding
H9J99_24510	COG4533	DNA binding
H9J99_24520	COG2050	protein possibly involved in aromatic compounds catabolism
H9J99_24535	COG2067	long-chain fatty acid transport protein
H9J99_24540	COG2267	carboxylic ester hydrolase activity
H9J99_24560	COG0861	Integral membrane protein TerC family
H9J99_24565	COG0737	Belongs to the 5'-nucleotidase family
H9J99_24570	COG3593	DNA synthesis involved in DNA repair
H9J99_24580	COG0583	DNA-binding transcription factor activity
H9J99_24585	COG2116	formate transmembrane transporter activity
H9J99_24590	COG2353	YceI-like domain
H9J99_24595	COG3038	cytochrome b561
H9J99_24610	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H9J99_24615	COG0513	Belongs to the DEAD box helicase family
H9J99_24620	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
H9J99_24625	COG0840	transmembrane signaling receptor activity
H9J99_24630	COG0546	phosphoglycolate phosphatase activity
H9J99_24720	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9J99_24840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9J99_24845	COG2759	Belongs to the formate--tetrahydrofolate ligase family
H9J99_24850	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
H9J99_24860	COG2207	Transcriptional regulator
H9J99_24865	COG1979	alcohol dehydrogenase
H9J99_24890	COG2271	Major facilitator Superfamily
H9J99_24895	COG0469	pyruvate kinase activity
H9J99_24900	COG1126	abc transporter atp-binding protein
H9J99_24905	COG0765	amino acid transport
H9J99_24910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9J99_24915	COG0765	amino acid transport
H9J99_24920	COG2199	diguanylate cyclase activity
H9J99_24920	COG2200	EAL domain
H9J99_24920	COG2203	Gaf domain
H9J99_24935	COG1609	Transcriptional regulator
H9J99_24940	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9J99_24940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9J99_24945	COG1105	Belongs to the carbohydrate kinase PfkB family
H9J99_24950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9J99_24950	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H9J99_24950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H9J99_24990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9J99_24995	COG0509	glycine decarboxylation via glycine cleavage system
H9J99_25000	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H9J99_25000	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H9J99_25005	COG2204	response regulator
H9J99_25025	COG1278	Cold shock
H9J99_25055	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9J99_25060	COG0583	DNA-binding transcription factor activity
H9J99_25065	COG2176	DNA-directed DNA polymerase activity
H9J99_25105	COG0242	peptide deformylase activity
H9J99_25125	COG2239	Acts as a magnesium transporter
H9J99_25145	COG0346	lactoylglutathione lyase activity
H9J99_25150	COG1902	pentaerythritol trinitrate reductase activity
H9J99_25170	COG5642	Protein of unknown function (DUF2384)
H9J99_25175	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
H9J99_25190	COG4565	transcriptional regulatory protein
H9J99_25195	COG3290	protein histidine kinase activity
H9J99_25200	COG0471	metal ion transport
H9J99_25230	COG2076	Multidrug Resistance protein
H9J99_25245	COG0671	phosphoesterase, PA-phosphatase related
H9J99_25255	COG2962	Rard protein
H9J99_25270	COG0784	Response regulator, receiver
H9J99_25270	COG0835	chemotaxis
H9J99_25290	COG2197	response regulator
H9J99_25300	COG3706	GGDEF domain
H9J99_25305	COG2197	response regulator
H9J99_25360	COG5492	domain, Protein
H9J99_25360	COG4932	domain protein
H9J99_25395	COG0840	transmembrane signaling receptor activity
H9J99_25515	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H9J99_25630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9J99_25660	COG2948	multi-organism process
H9J99_25675	COG3701	Conjugal transfer protein
H9J99_25685	COG4962	Type ii secretion system protein e
H9J99_25695	COG3451	type IV secretory pathway VirB4
H9J99_26040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9J99_26145	COG4974	Belongs to the 'phage' integrase family
H9J99_26250	COG1475	DNA binding