locus-tag	class	description
LZI70_00020	COG0840	transmembrane signaling receptor activity
LZI70_00025	COG1254	Belongs to the acylphosphatase family
LZI70_00030	COG2920	part of a sulfur-relay system
LZI70_00035	COG0670	Belongs to the BI1 family
LZI70_00040	COG1126	abc transporter atp-binding protein
LZI70_00045	COG0765	amino acid transport
LZI70_00050	COG4597	amino acid ABC transporter
LZI70_00055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LZI70_00065	COG1666	GTP binding
LZI70_00070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZI70_00085	COG2996	Protein conserved in bacteria
LZI70_00090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LZI70_00090	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LZI70_00095	COG3008	intermembrane lipid transfer
LZI70_00100	COG2995	paraquat-inducible protein a
LZI70_00105	COG1132	(ABC) transporter
LZI70_00110	COG1956	GAF domain-containing protein
LZI70_00115	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
LZI70_00130	COG0308	aminopeptidase N
LZI70_00140	COG2902	Dehydrogenase
LZI70_00145	COG0167	dihydroorotate dehydrogenase activity
LZI70_00165	COG0488	(ABC) transporter
LZI70_00185	COG1067	ATP-dependent peptidase activity
LZI70_00190	COG3120	sequence-specific DNA binding
LZI70_00230	COG3278	Belongs to the heme-copper respiratory oxidase family
LZI70_00245	COG2010	Cytochrome c
LZI70_00255	COG2217	Heavy metal translocating P-type atpase
LZI70_00270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZI70_00275	COG0589	response to stress
LZI70_00280	COG0037	tRNA processing
LZI70_00300	COG3842	ATPase activity
LZI70_00310	COG1177	transmembrane transport
LZI70_00320	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LZI70_00325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LZI70_00330	COG0004	ammonium transporteR
LZI70_00345	COG0437	4 iron, 4 sulfur cluster binding
LZI70_00350	COG3383	formate dehydrogenase (NAD+) activity
LZI70_00350	COG0243	molybdopterin cofactor binding
LZI70_00380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LZI70_00390	COG0488	(ABC) transporter
LZI70_00405	COG0840	transmembrane signaling receptor activity
LZI70_00420	COG4191	Histidine kinase
LZI70_00425	COG2204	response regulator
LZI70_00435	COG4662	Binding-protein-dependent transport system inner membrane component
LZI70_00440	COG3842	ATPase activity
LZI70_00445	COG0746	molybdenum cofactor guanylyltransferase activity
LZI70_00450	COG0303	'Molybdopterin
LZI70_00460	COG1940	carbohydrate kinase activity
LZI70_00465	COG3148	PFAM DTW domain containing protein
LZI70_00480	COG0791	NLP P60 protein
LZI70_00500	COG0307	riboflavin synthase, alpha
LZI70_00540	COG4176	ABC-type proline glycine betaine transport system permease component
LZI70_00545	COG4175	Glycine betaine
LZI70_00545	COG3448	diguanylate cyclase activity
LZI70_00555	COG2204	response regulator
LZI70_00565	COG0297	glycogen (starch) synthase activity
LZI70_00605	COG1215	transferase activity, transferring glycosyl groups
LZI70_00610	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LZI70_00615	COG4160	amino acid transport
LZI70_00620	COG4215	(ABC) transporter
LZI70_00625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LZI70_00630	COG1126	abc transporter atp-binding protein
LZI70_00635	COG1132	(ABC) transporter
LZI70_00660	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LZI70_00670	COG1609	Transcriptional regulator
LZI70_00685	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZI70_00690	COG0826	peptidase U32
LZI70_00715	COG0589	response to stress
LZI70_00720	COG0415	Belongs to the DNA photolyase family
LZI70_00725	COG3046	protein related to deoxyribodipyrimidine photolyase
LZI70_00740	COG0419	ATPase involved in DNA repair
LZI70_00745	COG0420	3'-5' exonuclease activity
LZI70_00770	COG1917	Cupin 2, conserved barrel domain protein
LZI70_00775	COG1028	Short-chain dehydrogenase reductase Sdr
LZI70_00780	COG0517	IMP dehydrogenase activity
LZI70_00785	COG2176	DNA-directed DNA polymerase activity
LZI70_00790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZI70_00800	COG1472	Belongs to the glycosyl hydrolase 3 family
LZI70_00810	COG0454	-acetyltransferase
LZI70_00815	COG4771	TonB-dependent receptor
LZI70_00820	COG0583	DNA-binding transcription factor activity
LZI70_00830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZI70_00835	COG2197	response regulator
LZI70_00845	COG1132	(ABC) transporter
LZI70_00855	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LZI70_00860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LZI70_00865	COG0363	glucosamine-6-phosphate deaminase activity
LZI70_00870	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LZI70_00875	COG4565	transcriptional regulatory protein
LZI70_00880	COG3290	protein histidine kinase activity
LZI70_00895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZI70_00910	COG1115	amino acid carrier protein
LZI70_00925	COG1115	amino acid carrier protein
LZI70_00930	COG1280	lysine exporter protein (LysE YggA)
LZI70_00935	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LZI70_00945	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LZI70_00945	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LZI70_00960	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LZI70_00975	COG1166	arginine decarboxylase activity
LZI70_00985	COG1309	transcriptional regulator
LZI70_00995	COG3097	Belongs to the UPF0267 family
LZI70_01000	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LZI70_01005	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LZI70_01025	COG4326	sporulation control protein
LZI70_01035	COG1228	amidohydrolase
LZI70_01040	COG0010	Belongs to the arginase family
LZI70_01045	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LZI70_01050	COG2986	histidine ammonia-lyase
LZI70_01060	COG5640	endopeptidase activity
LZI70_01070	COG0277	FAD linked oxidase domain protein
LZI70_01070	COG0247	lactate metabolic process
LZI70_01105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LZI70_01115	COG1643	Atp-dependent helicase
LZI70_01120	COG0281	malic enzyme
LZI70_01125	COG2949	membrane
LZI70_01130	COG0471	metal ion transport
LZI70_01150	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LZI70_01165	COG0492	ferredoxin-NADP+ reductase activity
LZI70_01170	COG4988	ABC transporter
LZI70_01175	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LZI70_01180	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
LZI70_01190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LZI70_01215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LZI70_01230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZI70_01235	COG3108	Peptidase M15
LZI70_01240	COG2989	Protein conserved in bacteria
LZI70_01265	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LZI70_01275	COG4235	cytochrome complex assembly
LZI70_01275	COG3088	subunit of a heme lyase
LZI70_01285	COG1138	Cytochrome C-type biogenesis protein
LZI70_01290	COG3301	Polysulphide reductase, NrfD
LZI70_01295	COG0437	4 iron, 4 sulfur cluster binding
LZI70_01305	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
LZI70_01310	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZI70_01325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LZI70_01330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZI70_01335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LZI70_01345	COG1546	Belongs to the CinA family
LZI70_01345	COG1058	Belongs to the CinA family
LZI70_01370	COG0019	diaminopimelate decarboxylase activity
LZI70_01410	COG0322	excinuclease ABC activity
LZI70_01415	COG2197	response regulator
LZI70_01420	COG0417	DNA replication proofreading
LZI70_01430	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LZI70_01445	COG1187	pseudouridine synthase activity
LZI70_01450	COG0009	L-threonylcarbamoyladenylate synthase
LZI70_01455	COG0613	PHP domain protein
LZI70_01465	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZI70_01470	COG0512	Glutamine amidotransferase of anthranilate synthase
LZI70_01475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LZI70_01480	COG0135	phosphoribosylanthranilate isomerase activity
LZI70_01480	COG0134	indole-3-glycerol-phosphate synthase activity
LZI70_01490	COG0159	tryptophan synthase activity
LZI70_01495	COG1301	dicarboxylic acid transport
LZI70_01505	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LZI70_01515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LZI70_01520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LZI70_01535	COG2917	probably involved in intracellular septation
LZI70_01540	COG1607	acyl-coa hydrolase
LZI70_01545	COG2350	Protein conserved in bacteria
LZI70_01555	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LZI70_01560	COG0583	DNA-binding transcription factor activity
LZI70_01575	COG1032	radical SAM domain protein
LZI70_01590	COG0463	Glycosyl transferase, family 2
LZI70_01595	COG0745	RESPONSE REGULATOR receiver
LZI70_01610	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZI70_01655	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LZI70_01670	COG0584	glycerophosphoryl diester phosphodiesterase
LZI70_01680	COG0583	DNA-binding transcription factor activity
LZI70_01690	COG2199	diguanylate cyclase activity
LZI70_01705	COG0784	Response regulator, receiver
LZI70_01705	COG5002	protein histidine kinase activity
LZI70_01720	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LZI70_01725	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LZI70_01730	COG2885	chlorophyll binding
LZI70_01735	COG0823	Involved in the tonB-independent uptake of proteins
LZI70_01750	COG0811	peptide transport
LZI70_01755	COG0824	Thioesterase
LZI70_01765	COG4890	Cyd operon protein YbgT
LZI70_01770	COG1294	oxidase, subunit
LZI70_01775	COG1271	oxidase subunit
LZI70_01780	COG2255	four-way junction helicase activity
LZI70_01785	COG0632	four-way junction helicase activity
LZI70_01790	COG0840	transmembrane signaling receptor activity
LZI70_01805	COG1801	Protein of unknown function DUF72
LZI70_01810	COG4106	trans-aconitate 2-methyltransferase activity
LZI70_01815	COG0500	methyltransferase
LZI70_01820	COG0189	ligase activity
LZI70_01820	COG4067	protein conserved in archaea
LZI70_01835	COG3383	formate dehydrogenase (NAD+) activity
LZI70_01840	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LZI70_01845	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LZI70_01850	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LZI70_01855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LZI70_01860	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LZI70_01865	COG0745	RESPONSE REGULATOR receiver
LZI70_01870	COG3381	protein complex oligomerization
LZI70_01875	COG1609	Transcriptional regulator
LZI70_01880	COG3070	regulator of competence-specific genes
LZI70_01900	COG0297	glycogen (starch) synthase activity
LZI70_01905	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LZI70_01910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LZI70_01920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LZI70_01930	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LZI70_01935	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LZI70_01940	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LZI70_01945	COG0542	response to heat
LZI70_01950	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LZI70_01955	COG1278	Cold shock
LZI70_01965	COG1187	pseudouridine synthase activity
LZI70_01975	COG1199	ATP-dependent helicase activity
LZI70_01980	COG0730	response to heat
LZI70_01995	COG2850	peptidyl-arginine hydroxylation
LZI70_02000	COG0840	transmembrane signaling receptor activity
LZI70_02015	COG4160	amino acid transport
LZI70_02045	COG1882	Formate acetyltransferase
LZI70_02055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LZI70_02060	COG3013	Belongs to the UPF0304 family
LZI70_02065	COG2766	serine protein kinase
LZI70_02070	COG2718	Belongs to the UPF0229 family
LZI70_02075	COG2719	SpoVR family
LZI70_02080	COG0616	signal peptide processing
LZI70_02085	COG1028	Short-chain dehydrogenase reductase Sdr
LZI70_02090	COG1252	NADH dehydrogenase
LZI70_02095	COG3150	esterase
LZI70_02120	COG0537	adenosine 5'-monophosphoramidase activity
LZI70_02145	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LZI70_02145	COG0617	tRNA 3'-terminal CCA addition
LZI70_02145	COG0517	IMP dehydrogenase activity
LZI70_02155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LZI70_02160	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZI70_02170	COG1902	pentaerythritol trinitrate reductase activity
LZI70_02175	COG0346	lactoylglutathione lyase activity
LZI70_02195	COG3040	lipid binding
LZI70_02200	COG1228	amidohydrolase
LZI70_02210	COG1522	sequence-specific DNA binding
LZI70_02215	COG1760	l-serine dehydratase
LZI70_02240	COG1609	Transcriptional regulator
LZI70_02245	COG3119	arylsulfatase activity
LZI70_02290	COG0745	RESPONSE REGULATOR receiver
LZI70_02295	COG5002	protein histidine kinase activity
LZI70_02295	COG3850	Histidine kinase
LZI70_02310	COG2824	Alkylphosphonate utilization operon protein PhnA
LZI70_02345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LZI70_02365	COG3126	Type III secretion system lipoprotein chaperone (YscW)
LZI70_02370	COG1946	Acyl-CoA thioesterase
LZI70_02375	COG1522	sequence-specific DNA binding
LZI70_02380	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LZI70_02390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZI70_02395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZI70_02450	COG2855	membrane
LZI70_02480	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LZI70_02485	COG1169	isochorismate synthase
LZI70_02490	COG0436	Aminotransferase
LZI70_02495	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LZI70_02500	COG0071	Belongs to the small heat shock protein (HSP20) family
LZI70_02505	COG0459	protein refolding
LZI70_02510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LZI70_02515	COG3655	Transcriptional regulator
LZI70_02545	COG2239	Acts as a magnesium transporter
LZI70_02560	COG0189	ligase activity
LZI70_02565	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LZI70_02580	COG1555	photosystem II stabilization
LZI70_02585	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZI70_02590	COG0776	regulation of translation
LZI70_02595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LZI70_02600	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LZI70_02605	COG0740	serine-type endopeptidase activity
LZI70_02610	COG0544	peptidyl-prolyl cis-trans isomerase activity
LZI70_02620	COG2204	response regulator
LZI70_02630	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LZI70_02635	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LZI70_02640	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LZI70_02645	COG3842	ATPase activity
LZI70_02655	COG1175	transmembrane transport
LZI70_02675	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LZI70_02680	COG1280	lysine exporter protein (LysE YggA)
LZI70_02685	COG2890	protein-(glutamine-N5) methyltransferase activity
LZI70_02690	COG2840	Smr protein MutS2
LZI70_02695	COG2062	phosphohistidine phosphatase, SixA
LZI70_02700	COG1025	Belongs to the peptidase M16 family
LZI70_02710	COG0183	Belongs to the thiolase family
LZI70_02725	COG2067	long-chain fatty acid transport protein
LZI70_02735	COG2853	Lipoprotein
LZI70_02745	COG3088	subunit of a heme lyase
LZI70_02745	COG4235	cytochrome complex assembly
LZI70_02750	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LZI70_02755	COG1138	Cytochrome C-type biogenesis protein
LZI70_02760	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LZI70_02765	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LZI70_02770	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LZI70_02775	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LZI70_02780	COG4133	protoheme IX ABC transporter activity
LZI70_02790	COG0835	chemotaxis
LZI70_02800	COG1192	Involved in chromosome partitioning
LZI70_02805	COG2201	protein-glutamate methylesterase activity
LZI70_02810	COG2198	Histidine kinase
LZI70_02810	COG0643	Histidine kinase
LZI70_02810	COG0784	Response regulator, receiver
LZI70_02815	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LZI70_02850	COG1684	flagellar biosynthetic protein fliR
LZI70_02855	COG1987	bacterial-type flagellum assembly
LZI70_02905	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LZI70_02915	COG1677	Flagellar hook-basal body complex protein FliE
LZI70_02935	COG1516	flagellar protein fliS
LZI70_02945	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
LZI70_02950	COG1334	flagellar protein FlaG
LZI70_02955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LZI70_02960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LZI70_02980	COG1705	Flagellar rod assembly protein muramidase FlgJ
LZI70_02980	COG3951	Flagellar rod assembly protein muramidase FlgJ
LZI70_02985	COG1706	bacterial-type flagellum-dependent cell motility
LZI70_02990	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LZI70_03000	COG4787	bacterial-type flagellum-dependent cell motility
LZI70_03020	COG1815	bacterial-type flagellum-dependent cell motility
LZI70_03025	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LZI70_03030	COG0784	Response regulator, receiver
LZI70_03030	COG0835	chemotaxis
LZI70_03100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LZI70_03120	COG1216	Glycosyl transferase, family 2
LZI70_03125	COG2986	histidine ammonia-lyase
LZI70_03150	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZI70_03160	COG1028	Short-chain dehydrogenase reductase Sdr
LZI70_03180	COG2217	Heavy metal translocating P-type atpase
LZI70_03180	COG2608	mercury ion transmembrane transporter activity
LZI70_03215	COG2840	Smr protein MutS2
LZI70_03220	COG1187	pseudouridine synthase activity
LZI70_03225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LZI70_03235	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LZI70_03240	COG2912	Transglutaminase-like superfamily
LZI70_03250	COG2890	protein-(glutamine-N5) methyltransferase activity
LZI70_03255	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LZI70_03260	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LZI70_03265	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LZI70_03270	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LZI70_03275	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LZI70_03280	COG0193	aminoacyl-tRNA hydrolase activity
LZI70_03285	COG0012	GTP binding
LZI70_03390	COG2706	6-phosphogluconolactonase activity
LZI70_03395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZI70_03400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LZI70_03405	COG1702	phosphate starvation-inducible protein PhoH
LZI70_03410	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LZI70_03415	COG4535	Mg2 and Co2 transporter CorC
LZI70_03420	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LZI70_03425	COG2888	peptidyl-tyrosine sulfation
LZI70_03430	COG0495	leucyl-tRNA aminoacylation
LZI70_03435	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LZI70_03440	COG1466	dna polymerase III delta subunit
LZI70_03445	COG0799	negative regulation of ribosome biogenesis
LZI70_03455	COG0768	penicillin binding
LZI70_03460	COG0772	Belongs to the SEDS family
LZI70_03465	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LZI70_03470	COG1686	Belongs to the peptidase S11 family
LZI70_03480	COG0321	lipoyl(octanoyl) transferase activity
LZI70_03485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LZI70_03490	COG0733	neurotransmitter:sodium symporter activity
LZI70_03500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZI70_03505	COG0514	ATP-dependent DNA helicase (RecQ)
LZI70_03510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LZI70_03520	COG2991	Protein conserved in bacteria
LZI70_03525	COG1477	protein flavinylation
LZI70_03530	COG2871	sodium ion transport
LZI70_03535	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LZI70_03540	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LZI70_03550	COG1805	sodium ion transport
LZI70_03555	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LZI70_03560	COG0271	Belongs to the BolA IbaG family
LZI70_03565	COG2813	Specifically methylates the guanine in position
LZI70_03575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZI70_03585	COG3248	Nucleoside-binding outer membrane protein
LZI70_03590	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LZI70_03595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LZI70_03600	COG2166	iron-sulfur cluster assembly
LZI70_03605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LZI70_03610	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LZI70_03620	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LZI70_03620	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LZI70_03635	COG1074	ATP-dependent DNA helicase activity
LZI70_03640	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LZI70_03655	COG3141	response to X-ray
LZI70_03670	COG2171	N-acyltransferase activity
LZI70_03675	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LZI70_03675	COG0047	phosphoribosylformylglycinamidine synthase activity
LZI70_03685	COG1846	Transcriptional regulator
LZI70_03690	COG1764	response to oxidative stress
LZI70_03700	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LZI70_03730	COG0484	heat shock protein binding
LZI70_03735	COG0443	Heat shock 70 kDa protein
LZI70_03745	COG1301	dicarboxylic acid transport
LZI70_03750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LZI70_03755	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LZI70_03760	COG0497	DNA recombination
LZI70_03765	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZI70_03770	COG2914	Belongs to the UPF0125 (RnfH) family
LZI70_03775	COG2867	negative regulation of translational initiation
LZI70_03845	COG0582	viral genome integration into host DNA
LZI70_03970	COG0204	Acyl-transferase
LZI70_03975	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LZI70_03980	COG1115	amino acid carrier protein
LZI70_03985	COG1584	GPR1 FUN34 yaaH family protein
LZI70_03990	COG0519	Catalyzes the synthesis of GMP from XMP
LZI70_03990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LZI70_03995	COG0516	GMP reductase activity
LZI70_03995	COG0517	IMP dehydrogenase activity
LZI70_04000	COG1570	exodeoxyribonuclease VII activity
LZI70_04005	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LZI70_04010	COG0830	nickel cation binding
LZI70_04020	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LZI70_04025	COG0804	urea catabolic process
LZI70_04030	COG0832	Belongs to the urease beta subunit family
LZI70_04035	COG0831	urea catabolic process
LZI70_04080	COG1160	GTP binding
LZI70_04085	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZI70_04090	COG2976	Protein conserved in bacteria
LZI70_04095	COG0124	histidyl-tRNA synthetase
LZI70_04100	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LZI70_04105	COG1426	Protein conserved in bacteria
LZI70_04110	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LZI70_04115	COG0105	UTP biosynthetic process
LZI70_04120	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZI70_04125	COG2975	iron-sulfur cluster assembly
LZI70_04130	COG0633	Ferredoxin
LZI70_04135	COG0443	Heat shock 70 kDa protein
LZI70_04150	COG0822	iron-sulfur transferase activity
LZI70_04155	COG1104	cysteine desulfurase activity
LZI70_04160	COG1959	2 iron, 2 sulfur cluster binding
LZI70_04165	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LZI70_04170	COG0483	inositol monophosphate 1-phosphatase activity
LZI70_04175	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZI70_04180	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZI70_04185	COG1862	Preprotein translocase
LZI70_04190	COG0343	queuine tRNA-ribosyltransferase activity
LZI70_04195	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LZI70_04200	COG0517	IMP dehydrogenase activity
LZI70_04205	COG0583	DNA-binding transcription factor activity
LZI70_04210	COG0450	alkyl hydroperoxide reductase
LZI70_04215	COG3142	Participates in the control of copper homeostasis
LZI70_04220	COG0704	Plays a role in the regulation of phosphate uptake
LZI70_04225	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LZI70_04230	COG0581	inorganic phosphate transmembrane transporter activity
LZI70_04240	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LZI70_04245	COG0248	Ppx GppA phosphatase
LZI70_04255	COG5002	protein histidine kinase activity
LZI70_04260	COG0745	RESPONSE REGULATOR receiver
LZI70_04265	COG2974	May be involved in recombination
LZI70_04270	COG0826	peptidase U32
LZI70_04275	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LZI70_04285	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LZI70_04330	COG0564	pseudouridine synthase activity
LZI70_04335	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZI70_04340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LZI70_04345	COG0077	Prephenate dehydratase
LZI70_04345	COG1605	Chorismate mutase
LZI70_04350	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LZI70_04355	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LZI70_04365	COG0488	(ABC) transporter
LZI70_04375	COG0739	heme binding
LZI70_04380	COG0287	Prephenate dehydrogenase
LZI70_04380	COG1605	Chorismate mutase
LZI70_04385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZI70_04395	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LZI70_04400	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LZI70_04410	COG1966	Carbon starvation protein
LZI70_04415	COG3275	phosphorelay sensor kinase activity
LZI70_04420	COG3279	Response regulator of the LytR AlgR family
LZI70_04425	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LZI70_04430	COG1047	Peptidyl-prolyl cis-trans
LZI70_04440	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LZI70_04445	COG0196	riboflavin kinase activity
LZI70_04450	COG0728	peptidoglycan biosynthetic process
LZI70_04455	COG0268	Binds directly to 16S ribosomal RNA
LZI70_04460	COG0640	Transcriptional regulator
LZI70_04465	COG0583	DNA-binding transcription factor activity
LZI70_04470	COG1283	sodium-dependent phosphate transmembrane transporter activity
LZI70_04475	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LZI70_04480	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LZI70_04485	COG0730	response to heat
LZI70_04495	COG0494	nUDIX hydrolase
LZI70_04520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LZI70_04530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LZI70_04535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZI70_04540	COG4974	Belongs to the 'phage' integrase family
LZI70_04545	COG0716	FMN binding
LZI70_04555	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LZI70_04560	COG0513	Belongs to the DEAD box helicase family
LZI70_04565	COG3022	response to hydroperoxide
LZI70_04570	COG1115	amino acid carrier protein
LZI70_04595	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LZI70_04600	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LZI70_04605	COG0083	homoserine kinase activity
LZI70_04620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LZI70_04625	COG0745	RESPONSE REGULATOR receiver
LZI70_04635	COG0784	Response regulator, receiver
LZI70_04635	COG5002	protein histidine kinase activity
LZI70_04635	COG2198	Histidine kinase
LZI70_04640	COG2203	Gaf domain
LZI70_04640	COG3706	GGDEF domain
LZI70_04640	COG4251	negative regulation of phosphorylation
LZI70_04640	COG5001	Diguanylate cyclase
LZI70_04645	COG1242	4 iron, 4 sulfur cluster binding
LZI70_04650	COG0069	glutamate synthase activity
LZI70_04650	COG0070	glutamate synthase
LZI70_04650	COG0067	glutamate synthase
LZI70_04660	COG0067	glutamate synthase
LZI70_04660	COG0069	glutamate synthase activity
LZI70_04660	COG0070	glutamate synthase
LZI70_04665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZI70_04675	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LZI70_04685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LZI70_04690	COG2860	membrane
LZI70_04700	COG0655	NAD(P)H dehydrogenase (quinone) activity
LZI70_04705	COG0583	DNA-binding transcription factor activity
LZI70_04710	COG0730	response to heat
LZI70_04715	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LZI70_04720	COG0505	Belongs to the CarA family
LZI70_04725	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LZI70_04730	COG0494	nUDIX hydrolase
LZI70_04735	COG0653	protein targeting
LZI70_04740	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LZI70_04745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LZI70_04750	COG0849	cell division
LZI70_04755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LZI70_04760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZI70_04765	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LZI70_04770	COG0772	Belongs to the SEDS family
LZI70_04775	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LZI70_04780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LZI70_04785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LZI70_04790	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LZI70_04795	COG0768	penicillin binding
LZI70_04800	COG3116	cell division
LZI70_04805	COG0275	rRNA processing
LZI70_04815	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LZI70_04830	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LZI70_04835	COG2823	Periplasmic or secreted lipoprotein
LZI70_04840	COG2969	positive regulation of protein catabolic process
LZI70_04845	COG0625	glutathione transferase activity
LZI70_04850	COG2857	Cytochrome c1
LZI70_04855	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LZI70_04860	COG0723	plastoquinol--plastocyanin reductase activity
LZI70_04865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LZI70_04875	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LZI70_04880	COG3105	Protein conserved in bacteria
LZI70_04890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LZI70_04905	COG3150	esterase
LZI70_04915	COG3151	Protein conserved in bacteria
LZI70_04920	COG0494	nUDIX hydrolase
LZI70_04925	COG1538	Outer membrane efflux protein
LZI70_04930	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LZI70_04930	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LZI70_04935	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LZI70_04945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZI70_04950	COG3025	triphosphatase activity
LZI70_04955	COG1392	Phosphate transport regulator
LZI70_04960	COG0306	phosphate transporter
LZI70_04965	COG4991	sh3 domain protein
LZI70_04975	COG3267	Type II secretory pathway component ExeA
LZI70_04975	COG3409	Peptidoglycan-binding domain 1 protein
LZI70_04980	COG0617	tRNA 3'-terminal CCA addition
LZI70_04985	COG1968	undecaprenyl-diphosphatase activity
LZI70_04995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZI70_05000	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LZI70_05005	COG0596	Alpha beta hydrolase
LZI70_05010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LZI70_05015	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LZI70_05020	COG1610	YqeY-like protein
LZI70_05040	COG2873	o-acetylhomoserine
LZI70_05045	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LZI70_05050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LZI70_05055	COG1349	DNA-binding transcription factor activity
LZI70_05060	COG0469	pyruvate kinase activity
LZI70_05065	COG1802	Transcriptional regulator
LZI70_05080	COG0028	Belongs to the TPP enzyme family
LZI70_05085	COG1022	Amp-dependent synthetase and ligase
LZI70_05120	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LZI70_05125	COG0473	3-isopropylmalate dehydrogenase activity
LZI70_05150	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LZI70_05155	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LZI70_05160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZI70_05165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LZI70_05170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LZI70_05175	COG2967	ApaG domain
LZI70_05190	COG3610	response to peptide
LZI70_05195	COG2966	Psort location CytoplasmicMembrane, score
LZI70_05200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LZI70_05205	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LZI70_05210	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LZI70_05215	COG0142	geranyltranstransferase activity
LZI70_05225	COG0039	L-malate dehydrogenase activity
LZI70_05230	COG1438	arginine binding
LZI70_05235	COG2358	TRAP transporter, solute receptor (TAXI family
LZI70_05245	COG0589	response to stress
LZI70_05250	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LZI70_05255	COG0564	pseudouridine synthase activity
LZI70_05265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LZI70_05270	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LZI70_05275	COG0312	modulator of DNA gyrase
LZI70_05280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LZI70_05295	COG0424	maF-like protein
LZI70_05300	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LZI70_05305	COG1792	Involved in formation and maintenance of cell shape
LZI70_05310	COG1077	Cell shape determining protein MreB Mrl
LZI70_05340	COG2165	general secretion pathway protein
LZI70_05345	COG2165	general secretion pathway protein
LZI70_05355	COG1459	type II secretion system
LZI70_05360	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZI70_05370	COG3409	Peptidoglycan-binding domain 1 protein
LZI70_05370	COG3267	Type II secretory pathway component ExeA
LZI70_05395	COG2199	diguanylate cyclase activity
LZI70_05395	COG2200	EAL domain
LZI70_05400	COG0629	single-stranded DNA binding
LZI70_05415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LZI70_05425	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LZI70_05430	COG0527	aspartate kinase activity
LZI70_05435	COG1410	methionine synthase
LZI70_05435	COG0646	methionine synthase
LZI70_05530	COG0175	sulfate reduction
LZI70_05535	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LZI70_05540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZI70_05565	COG0735	belongs to the Fur family
LZI70_05575	COG0166	Belongs to the GPI family
LZI70_05580	COG0432	Pfam Uncharacterised protein family UPF0047
LZI70_05590	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LZI70_05605	COG0359	binds to the 23S rRNA
LZI70_05620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LZI70_05625	COG0557	exoribonuclease II activity
LZI70_05630	COG0402	S-adenosylhomocysteine deaminase activity
LZI70_05635	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LZI70_05640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LZI70_05645	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LZI70_05650	COG0330	HflC and HflK could
LZI70_05655	COG0330	HflC and HflK could
LZI70_05660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LZI70_05665	COG1923	regulation of RNA biosynthetic process
LZI70_05670	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LZI70_05675	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LZI70_05680	COG0860	N-Acetylmuramoyl-L-alanine amidase
LZI70_05685	COG0802	atpase or kinase
LZI70_05690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LZI70_05785	COG1162	GTPase activity
LZI70_05790	COG0688	phosphatidylethanolamine metabolic process
LZI70_05795	COG0471	metal ion transport
LZI70_05795	COG0490	domain, Protein
LZI70_05805	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LZI70_05810	COG1053	succinate dehydrogenase
LZI70_05815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZI70_05820	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LZI70_05835	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LZI70_05840	COG1509	lysine 2,3-aminomutase activity
LZI70_05845	COG1285	pathogenesis
LZI70_05850	COG2203	Gaf domain
LZI70_05850	COG2199	diguanylate cyclase activity
LZI70_05860	COG0459	protein refolding
LZI70_05865	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LZI70_05870	COG0534	Mate efflux family protein
LZI70_05875	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LZI70_05885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LZI70_05890	COG1215	transferase activity, transferring glycosyl groups
LZI70_05895	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LZI70_05905	COG0438	transferase activity, transferring glycosyl groups
LZI70_05920	COG1215	transferase activity, transferring glycosyl groups
LZI70_05925	COG5433	transposase activity
LZI70_05955	COG0489	protein tyrosine kinase activity
LZI70_05955	COG3206	protein involved in exopolysaccharide biosynthesis
LZI70_05965	COG1596	polysaccharide export
LZI70_05970	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LZI70_05990	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZI70_05995	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LZI70_06005	COG1045	serine acetyltransferase
LZI70_06010	COG4942	peptidase
LZI70_06025	COG1560	Kdo2-lipid A biosynthetic process
LZI70_06030	COG0859	PFAM glycosyl transferase family 9
LZI70_06035	COG1519	Transferase
LZI70_06045	COG0726	polysaccharide deacetylase
LZI70_06045	COG1649	PFAM Uncharacterised BCR, COG1649
LZI70_06065	COG0318	PFAM AMP-dependent synthetase and ligase
LZI70_06080	COG1028	Short-chain dehydrogenase reductase Sdr
LZI70_06085	COG1083	cytidylyl-transferase
LZI70_06105	COG2089	acid synthase
LZI70_06110	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LZI70_06115	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LZI70_06125	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LZI70_06130	COG3083	sulfuric ester hydrolase activity
LZI70_06135	COG3642	lipopolysaccharide core region biosynthetic process
LZI70_06140	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LZI70_06145	COG0859	PFAM glycosyl transferase family 9
LZI70_06150	COG0463	Glycosyl transferase, family 2
LZI70_06155	COG0438	transferase activity, transferring glycosyl groups
LZI70_06160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LZI70_06170	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LZI70_06185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LZI70_06190	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LZI70_06195	COG2003	Belongs to the UPF0758 family
LZI70_06205	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LZI70_06210	COG1309	transcriptional regulator
LZI70_06215	COG1560	Kdo2-lipid A biosynthetic process
LZI70_06220	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LZI70_06225	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LZI70_06230	COG1561	YicC-like family, N-terminal region
LZI70_06255	COG2252	PERMEase
LZI70_06260	COG0194	GDP metabolic process
LZI70_06265	COG1758	RNA polymerase activity
LZI70_06270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZI70_06275	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LZI70_06290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZI70_06295	COG2183	response to ionizing radiation
LZI70_06305	COG0596	Alpha beta hydrolase
LZI70_06310	COG1040	competence protein
LZI70_06315	COG0316	Belongs to the HesB IscA family
LZI70_06315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LZI70_06320	COG0494	nUDIX hydrolase
LZI70_06325	COG1218	3'(2'),5'-bisphosphate nucleotidase
LZI70_06340	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LZI70_06345	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LZI70_06350	COG3156	type II secretion system protein K
LZI70_06355	COG4795	General secretion pathway protein
LZI70_06360	COG2165	general secretion pathway protein
LZI70_06365	COG2165	general secretion pathway protein
LZI70_06370	COG2165	general secretion pathway protein
LZI70_06375	COG1459	type II secretion system
LZI70_06380	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZI70_06390	COG3031	protein transport across the cell outer membrane
LZI70_06395	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LZI70_06405	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LZI70_06415	COG0456	acetyltransferase
LZI70_06420	COG1490	D-aminoacyl-tRNA deacylase activity
LZI70_06425	COG1295	ribonuclease BN
LZI70_06435	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LZI70_06440	COG1217	gtp-binding protein TYPA
LZI70_06445	COG0174	glutamine synthetase
LZI70_06455	COG3852	Histidine kinase
LZI70_06480	COG3078	GTPase activator activity
LZI70_06505	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZI70_06505	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZI70_06510	COG0456	acetyltransferase
LZI70_06520	COG0084	hydrolase, TatD family'
LZI70_06525	COG0805	protein transport
LZI70_06530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LZI70_06535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LZI70_06540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LZI70_06545	COG3165	ubiquinone biosynthetic process from chorismate
LZI70_06550	COG2226	methyltransferase
LZI70_06555	COG1322	Protein conserved in bacteria
LZI70_06565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZI70_06570	COG3037	sugar-specific permease SgaT UlaA
LZI70_06585	COG2081	HI0933 family
LZI70_06595	COG1528	Iron-storage protein
LZI70_06600	COG0589	response to stress
LZI70_06615	COG0742	ribosomal rna small subunit methyltransferase
LZI70_06620	COG5001	Diguanylate cyclase
LZI70_06620	COG5002	protein histidine kinase activity
LZI70_06625	COG1522	sequence-specific DNA binding
LZI70_06630	COG0339	signal peptide processing
LZI70_06635	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LZI70_06640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZI70_06685	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LZI70_06690	COG0601	transmembrane transport
LZI70_06740	COG1309	transcriptional regulator
LZI70_06745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZI70_06750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZI70_06755	COG2960	long-chain fatty acid transporting porin activity
LZI70_06760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LZI70_06765	COG0583	DNA-binding transcription factor activity
LZI70_06810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LZI70_06815	COG1739	Uncharacterized protein family UPF0029
LZI70_06820	COG1024	Enoyl-CoA hydratase
LZI70_06820	COG1250	3-hydroxyacyl-CoA dehydrogenase
LZI70_06825	COG0183	Belongs to the thiolase family
LZI70_06830	COG0604	alcohol dehydrogenase
LZI70_06845	COG0425	Belongs to the sulfur carrier protein TusA family
LZI70_06855	COG2119	membrane
LZI70_06860	COG0752	glycyl-tRNA synthetase alpha subunit
LZI70_06865	COG0751	glycine-tRNA ligase activity
LZI70_06870	COG0366	Alpha amylase catalytic
LZI70_06875	COG3977	Valine--pyruvate aminotransferase
LZI70_06880	COG0071	Belongs to the small heat shock protein (HSP20) family
LZI70_06885	COG0187	DNA topoisomerase II activity
LZI70_06890	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LZI70_06895	COG0592	DNA-directed DNA polymerase activity
LZI70_06900	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LZI70_06915	COG1126	abc transporter atp-binding protein
LZI70_06920	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LZI70_06930	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LZI70_06935	COG0706	membrane insertase activity
LZI70_06945	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LZI70_06950	COG0445	tRNA wobble uridine modification
LZI70_06955	COG0357	Ribosomal RNA small subunit methyltransferase G
LZI70_06960	COG1192	Involved in chromosome partitioning
LZI70_06965	COG1475	DNA binding
LZI70_06970	COG3312	ion transport
LZI70_06985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LZI70_06990	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LZI70_06995	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LZI70_07000	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LZI70_07005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LZI70_07010	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LZI70_07020	COG2814	Major facilitator Superfamily
LZI70_07025	COG0583	DNA-binding transcription factor activity
LZI70_07040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZI70_07045	COG3978	acetolactate synthase activity
LZI70_07055	COG0606	chelatase, subunit chli
LZI70_07065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZI70_07070	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LZI70_07080	COG3084	Protein conserved in bacteria
LZI70_07090	COG4326	sporulation control protein
LZI70_07095	COG1272	protein, Hemolysin III
LZI70_07105	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LZI70_07110	COG0569	domain protein
LZI70_07115	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LZI70_07115	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LZI70_07135	COG0758	DNA mediated transformation
LZI70_07140	COG2922	Belongs to the Smg family
LZI70_07145	COG0551	DNA topoisomerase type I activity
LZI70_07150	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LZI70_07155	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LZI70_07160	COG0009	L-threonylcarbamoyladenylate synthase
LZI70_07165	COG0408	coproporphyrinogen oxidase activity
LZI70_07170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LZI70_07180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LZI70_07230	COG2132	Multicopper oxidase
LZI70_07235	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LZI70_07250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LZI70_07270	COG0006	proline dipeptidase activity
LZI70_07270	COG0006	proline dipeptidase activity
LZI70_07300	COG3220	belongs to the UPF0276 family
LZI70_07310	COG0210	DNA helicase
LZI70_07315	COG0405	Gamma-glutamyltransferase
LZI70_07320	COG1280	lysine exporter protein (LysE YggA)
LZI70_07330	COG2962	Rard protein
LZI70_07335	COG0514	ATP-dependent DNA helicase (RecQ)
LZI70_07345	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LZI70_07350	COG0248	Ppx GppA phosphatase
LZI70_07355	COG0513	Belongs to the DEAD box helicase family
LZI70_07360	COG3118	belongs to the thioredoxin family
LZI70_07375	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LZI70_07440	COG3071	HemY protein
LZI70_07445	COG2959	enzyme of heme biosynthesis
LZI70_07450	COG1587	Uroporphyrinogen-III synthase
LZI70_07455	COG0181	hydroxymethylbilane synthase activity
LZI70_07465	COG1965	Belongs to the frataxin family
LZI70_07475	COG0019	diaminopimelate decarboxylase activity
LZI70_07480	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LZI70_07490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZI70_07495	COG1011	Hydrolase
LZI70_07500	COG3287	FIST C domain
LZI70_07500	COG2200	EAL domain
LZI70_07500	COG2199	diguanylate cyclase activity
LZI70_07505	COG2199	diguanylate cyclase activity
LZI70_07505	COG2200	EAL domain
LZI70_07505	COG3287	FIST C domain
LZI70_07510	COG3148	PFAM DTW domain containing protein
LZI70_07525	COG0561	phosphatase activity
LZI70_07530	COG2267	carboxylic ester hydrolase activity
LZI70_07535	COG1280	lysine exporter protein (LysE YggA)
LZI70_07540	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LZI70_07545	COG0640	Transcriptional regulator
LZI70_07550	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZI70_07590	COG2095	MarC family integral membrane protein
LZI70_07600	COG0742	ribosomal rna small subunit methyltransferase
LZI70_07605	COG0552	protein localization to endoplasmic reticulum
LZI70_07610	COG2884	Cell division ATP-binding protein ftsE
LZI70_07615	COG2177	Part of the ABC transporter FtsEX involved in
LZI70_07625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZI70_07635	COG1580	Controls the rotational direction of flagella during chemotaxis
LZI70_07640	COG3161	chorismate lyase activity
LZI70_07645	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LZI70_07650	COG2937	Belongs to the GPAT DAPAT family
LZI70_07655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LZI70_07665	COG0534	Mate efflux family protein
LZI70_07670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZI70_07685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LZI70_07690	COG4206	TonB-dependent receptor
LZI70_07695	COG0137	argininosuccinate synthase activity
LZI70_07700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LZI70_07790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZI70_07800	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LZI70_07810	COG1072	(Pantothenic acid kinase))
LZI70_07835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZI70_07840	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LZI70_07845	COG0250	Participates in transcription elongation, termination and antitermination
LZI70_07855	COG0081	regulation of translation
LZI70_07860	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LZI70_07870	COG0085	RNA polymerase activity
LZI70_07880	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LZI70_07885	COG2816	NAD+ diphosphatase activity
LZI70_07905	COG3068	Protein conserved in bacteria
LZI70_07910	COG1253	flavin adenine dinucleotide binding
LZI70_07925	COG0151	Belongs to the GarS family
LZI70_07930	COG0138	bifunctional purine biosynthesis protein purh
LZI70_07945	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LZI70_07950	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LZI70_07955	COG2264	protein methyltransferase activity
LZI70_07960	COG0439	Biotin carboxylase
LZI70_07965	COG0511	ligase activity, forming carbon-carbon bonds
LZI70_07970	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LZI70_07975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LZI70_07990	COG2814	Major facilitator Superfamily
LZI70_07995	COG0784	Response regulator, receiver
LZI70_07995	COG2198	Histidine kinase
LZI70_07995	COG2205	protein histidine kinase activity
LZI70_08010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZI70_08020	COG2095	MarC family integral membrane protein
LZI70_08030	COG4232	protein-disulfide reductase activity
LZI70_08035	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LZI70_08040	COG1027	Aspartate ammonia-lyase
LZI70_08045	COG3030	protein affecting phage T7 exclusion by the F plasmid
LZI70_08050	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LZI70_08055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LZI70_08060	COG2205	protein histidine kinase activity
LZI70_08065	COG0745	RESPONSE REGULATOR receiver
LZI70_08075	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LZI70_08085	COG0149	triose-phosphate isomerase activity
LZI70_08110	COG1494	fructose-1,6-bisphosphatase
LZI70_08115	COG3074	FtsZ-dependent cytokinesis
LZI70_08120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LZI70_08125	COG1575	Belongs to the MenA family. Type 1 subfamily
LZI70_08130	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LZI70_08135	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LZI70_08145	COG1609	Transcriptional regulator
LZI70_08150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LZI70_08155	COG0254	rRNA binding
LZI70_08160	COG0281	malic enzyme
LZI70_08165	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LZI70_08170	COG0626	cystathionine gamma-synthase activity
LZI70_08175	COG0460	homoserine dehydrogenase
LZI70_08175	COG0527	aspartate kinase activity
LZI70_08180	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LZI70_08190	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LZI70_08195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZI70_08200	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LZI70_08215	COG0165	Argininosuccinate lyase
LZI70_08215	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LZI70_08225	COG0251	oxidation-reduction process
LZI70_08230	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LZI70_08230	COG0678	peroxiredoxin activity
LZI70_08240	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LZI70_08275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LZI70_08285	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LZI70_08290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LZI70_08295	COG0546	phosphoglycolate phosphatase activity
LZI70_08300	COG0180	Tryptophanyl-tRNA synthetase
LZI70_08310	COG0512	Glutamine amidotransferase of anthranilate synthase
LZI70_08315	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LZI70_08325	COG1012	belongs to the aldehyde dehydrogenase family
LZI70_08335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZI70_08340	COG3954	Phosphoribulokinase
LZI70_08345	COG3089	Belongs to the UPF0270 family
LZI70_08350	COG0429	hydrolase of the alpha beta-hydrolase fold
LZI70_08360	COG0488	(ABC) transporter
LZI70_08365	COG2249	NAD(P)H dehydrogenase (quinone) activity
LZI70_08375	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LZI70_08380	COG1047	Peptidyl-prolyl cis-trans
LZI70_08385	COG1446	asparaginase
LZI70_08390	COG2900	Belongs to the SlyX family
LZI70_08400	COG0545	Peptidyl-prolyl cis-trans isomerase
LZI70_08405	COG2964	Protein conserved in bacteria
LZI70_08410	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LZI70_08415	COG2923	Belongs to the DsrF TusC family
LZI70_08435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LZI70_08440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LZI70_08445	COG2906	2 iron, 2 sulfur cluster binding
LZI70_08455	COG0051	transcription antitermination factor activity, RNA binding
LZI70_08460	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LZI70_08465	COG0088	Forms part of the polypeptide exit tunnel
LZI70_08470	COG0089	rRNA binding
LZI70_08475	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LZI70_08480	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LZI70_08495	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LZI70_08505	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LZI70_08515	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LZI70_08525	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LZI70_08530	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LZI70_08535	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LZI70_08540	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LZI70_08545	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LZI70_08550	COG1841	ribosomal large subunit assembly
LZI70_08555	COG0200	Binds to the 23S rRNA
LZI70_08560	COG0201	protein transport
LZI70_08565	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LZI70_08570	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LZI70_08575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LZI70_08580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LZI70_08585	COG0202	RNA polymerase activity
LZI70_08590	COG0203	ribosomal protein L17
LZI70_08600	COG0545	Peptidyl-prolyl cis-trans isomerase
LZI70_08605	COG3266	domain, Protein
LZI70_08605	COG3061	Opacity-associated protein A
LZI70_08615	COG2153	protein acetylation
LZI70_08635	COG0737	Belongs to the 5'-nucleotidase family
LZI70_08640	COG0175	sulfate reduction
LZI70_08645	COG2895	sulfate adenylyltransferase (ATP) activity
LZI70_08650	COG0471	metal ion transport
LZI70_08650	COG3273	potassium ion transport
LZI70_08655	COG0529	Catalyzes the synthesis of activated sulfate
LZI70_08690	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LZI70_08705	COG0729	surface antigen
LZI70_08710	COG2911	Protein conserved in bacteria
LZI70_08715	COG2105	PFAM AIG2 family protein
LZI70_08725	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LZI70_08730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LZI70_08735	COG0163	prenyltransferase activity
LZI70_08740	COG4143	(ABC) transporter
LZI70_08745	COG1178	ABC-type Fe3 transport system permease component
LZI70_08750	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LZI70_08755	COG3028	Belongs to the UPF0307 family
LZI70_08760	COG0312	modulator of DNA gyrase
LZI70_08765	COG2239	Acts as a magnesium transporter
LZI70_08770	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZI70_08775	COG1660	Displays ATPase and GTPase activities
LZI70_08780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZI70_08785	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LZI70_08795	COG1137	ATPase activity
LZI70_08800	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LZI70_08810	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LZI70_08815	COG0517	IMP dehydrogenase activity
LZI70_08815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LZI70_08825	COG1127	ABC transporter
LZI70_08830	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LZI70_08835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LZI70_08840	COG2854	intermembrane phospholipid transfer
LZI70_08850	COG5007	Belongs to the BolA IbaG family
LZI70_08855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LZI70_08860	COG0204	Acyl-transferase
LZI70_08865	COG0251	oxidation-reduction process
LZI70_08870	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LZI70_08910	COG0525	valine-tRNA ligase activity
LZI70_08915	COG2927	DNA polymerase III (CHI subunit)
LZI70_08920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LZI70_08925	COG0795	lipopolysaccharide-transporting ATPase activity
LZI70_08930	COG0795	lipopolysaccharide-transporting ATPase activity
LZI70_08950	COG0745	RESPONSE REGULATOR receiver
LZI70_08955	COG3706	GGDEF domain
LZI70_08965	COG3437	response regulator, receiver
LZI70_09035	COG0840	transmembrane signaling receptor activity
LZI70_09075	COG0741	lytic transglycosylase activity
LZI70_09080	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LZI70_09095	COG2066	Belongs to the glutaminase family
LZI70_09100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LZI70_09105	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LZI70_09120	COG0762	integral membrane protein
LZI70_09125	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LZI70_09130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LZI70_09155	COG1678	Uncharacterized ACR, COG1678
LZI70_09160	COG0189	ligase activity
LZI70_09165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LZI70_09170	COG2356	endonuclease I
LZI70_09175	COG3091	SprT-like family
LZI70_09185	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LZI70_09195	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LZI70_09205	COG0191	fructose-bisphosphate aldolase activity
LZI70_09210	COG0668	transmembrane transport
LZI70_09235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZI70_09240	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LZI70_09245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LZI70_09255	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LZI70_09260	COG3079	Belongs to the UPF0149 family
LZI70_09265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZI70_09270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LZI70_09280	COG0442	prolyl-tRNA aminoacylation
LZI70_09285	COG0354	folic acid binding
LZI70_09290	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LZI70_09295	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LZI70_09300	COG1595	DNA-templated transcription, initiation
LZI70_09320	COG0481	GTPase activity
LZI70_09330	COG0571	ribonuclease III activity
LZI70_09335	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LZI70_09340	COG1381	Involved in DNA repair and RecF pathway recombination
LZI70_09345	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LZI70_09350	COG0736	holo-[acyl-carrier-protein] synthase activity
LZI70_09355	COG3437	response regulator, receiver
LZI70_09355	COG2205	protein histidine kinase activity
LZI70_09355	COG3850	Histidine kinase
LZI70_09355	COG4999	Histidine kinase
LZI70_09360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LZI70_09365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LZI70_09370	COG3956	TIGRFAM MazG family protein
LZI70_09380	COG0148	phosphopyruvate hydratase activity
LZI70_09385	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LZI70_09390	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LZI70_09400	COG0585	pseudouridine synthase activity
LZI70_09405	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LZI70_09410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LZI70_09420	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LZI70_09425	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LZI70_09430	COG1546	Belongs to the CinA family
LZI70_09435	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LZI70_09440	COG3152	Membrane
LZI70_09450	COG0527	aspartate kinase activity
LZI70_09510	COG3630	sodium ion export across plasma membrane
LZI70_09515	COG5016	pyruvate
LZI70_09515	COG0511	ligase activity, forming carbon-carbon bonds
LZI70_09520	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
LZI70_09530	COG1238	metal cluster binding
LZI70_09535	COG0612	Peptidase, M16
LZI70_09550	COG1854	S-ribosylhomocysteine lyase activity
LZI70_09555	COG4536	flavin adenine dinucleotide binding
LZI70_09560	COG4137	Cytochrome C assembly protein
LZI70_09565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LZI70_09575	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LZI70_09580	COG0336	Belongs to the RNA methyltransferase TrmD family
LZI70_09595	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LZI70_09600	COG0237	dephospho-CoA kinase activity
LZI70_09610	COG1459	type II secretion system
LZI70_09615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LZI70_09620	COG4969	Belongs to the N-Me-Phe pilin family
LZI70_09625	COG0157	Belongs to the NadC ModD family
LZI70_09640	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LZI70_09645	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZI70_09650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LZI70_09665	COG0288	reversible hydration of carbon dioxide
LZI70_09670	COG0659	secondary active sulfate transmembrane transporter activity
LZI70_09675	COG1131	(ABC) transporter
LZI70_09680	COG0842	Transport permease protein
LZI70_09685	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LZI70_09690	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LZI70_09695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZI70_09710	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LZI70_09715	COG1489	DNA binding
LZI70_09720	COG1643	Atp-dependent helicase
LZI70_09725	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LZI70_09730	COG1752	Esterase of the alpha-beta hydrolase superfamily
LZI70_09735	COG1049	propionate catabolic process, 2-methylcitrate cycle
LZI70_09750	COG0004	ammonium transporteR
LZI70_09755	COG1840	ABC-type Fe3 transport system, periplasmic component
LZI70_09765	COG3842	ATPase activity
LZI70_09770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZI70_09785	COG2971	BadF BadG BcrA BcrD
LZI70_09795	COG4608	Belongs to the ABC transporter superfamily
LZI70_09800	COG0444	Belongs to the ABC transporter superfamily
LZI70_09805	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LZI70_09815	COG0747	negative chemotaxis
LZI70_09825	COG2205	protein histidine kinase activity
LZI70_09825	COG0784	Response regulator, receiver
LZI70_09835	COG0628	permease
LZI70_09840	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LZI70_09845	COG0316	Belongs to the HesB IscA family
LZI70_09860	COG0739	heme binding
LZI70_09865	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LZI70_09870	COG2239	Acts as a magnesium transporter
LZI70_09875	COG2027	D-alanyl-D-alanine carboxypeptidase
LZI70_09880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LZI70_09885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LZI70_09890	COG1534	Rna-binding protein
LZI70_09895	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LZI70_09900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LZI70_09905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LZI70_09915	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LZI70_09930	COG0779	Required for maturation of 30S ribosomal subunits
LZI70_09935	COG0195	Participates in both transcription termination and antitermination
LZI70_09945	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LZI70_09950	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LZI70_09955	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LZI70_09975	COG0534	Mate efflux family protein
LZI70_09980	COG0826	peptidase U32
LZI70_09985	COG0826	peptidase U32
LZI70_09995	COG3154	lipid carrier protein
LZI70_10000	COG3153	acetyltransferase
LZI70_10010	COG0456	acetyltransferase
LZI70_10015	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LZI70_10025	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LZI70_10035	COG0084	hydrolase, TatD family'
LZI70_10040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LZI70_10045	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LZI70_10050	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LZI70_10060	COG0813	purine-nucleoside phosphorylase activity
LZI70_10070	COG0560	Phosphoserine phosphatase
LZI70_10080	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LZI70_10085	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LZI70_10090	COG4628	conserved protein (DUF2132)
LZI70_10095	COG0583	DNA-binding transcription factor activity
LZI70_10105	COG1022	Amp-dependent synthetase and ligase
LZI70_10140	COG4964	Belongs to the GSP D family
LZI70_10190	COG2059	Chromate
LZI70_10215	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LZI70_10235	COG2195	Cleaves the N-terminal amino acid of tripeptides
LZI70_10240	COG2252	PERMEase
LZI70_10245	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LZI70_10250	COG1073	alpha beta
LZI70_10265	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LZI70_10270	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LZI70_10275	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZI70_10275	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LZI70_10295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LZI70_10300	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LZI70_10305	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LZI70_10325	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LZI70_10330	COG0142	geranyltranstransferase activity
LZI70_10335	COG1722	exodeoxyribonuclease VII activity
LZI70_10340	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LZI70_10350	COG0301	tRNA thio-modification
LZI70_10350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LZI70_10355	COG0625	glutathione transferase activity
LZI70_10360	COG0583	DNA-binding transcription factor activity
LZI70_10370	COG2363	Small membrane protein
LZI70_10375	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LZI70_10380	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LZI70_10385	COG1611	Belongs to the LOG family
LZI70_10400	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LZI70_10400	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LZI70_10410	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
LZI70_10415	COG1464	Belongs to the NlpA lipoprotein family
LZI70_10420	COG2011	ABC-type metal ion transport system permease component
LZI70_10430	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LZI70_10445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LZI70_10445	COG1263	PTS System
LZI70_10450	COG0366	Alpha amylase catalytic
LZI70_10490	COG0442	prolyl-tRNA aminoacylation
LZI70_10495	COG1720	tRNA m6t6A37 methyltransferase activity
LZI70_10500	COG0254	rRNA binding
LZI70_10510	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
LZI70_10520	COG1671	Belongs to the UPF0178 family
LZI70_10545	COG3098	single-species biofilm formation
LZI70_10550	COG0564	pseudouridine synthase activity
LZI70_10560	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LZI70_10565	COG0024	Methionine aminopeptidase
LZI70_10580	COG0528	UMP kinase activity
LZI70_10585	COG0233	cytoplasmic translational termination
LZI70_10590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LZI70_10595	COG0575	Belongs to the CDS family
LZI70_10605	COG0750	zinc metalloprotease
LZI70_10615	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LZI70_10625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LZI70_10630	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZI70_10640	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LZI70_10645	COG0587	DNA-directed DNA polymerase activity
LZI70_10650	COG0825	malonyl-CoA metabolic process
LZI70_10655	COG0037	tRNA processing
LZI70_10665	COG0347	Belongs to the P(II) protein family
LZI70_10680	COG0741	lytic transglycosylase activity
LZI70_10680	COG1388	LysM domain
LZI70_10685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZI70_10690	COG2226	methyltransferase
LZI70_10710	COG1960	acyl-CoA dehydrogenase activity
LZI70_10715	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LZI70_10720	COG0121	glutamine amidotransferase
LZI70_10725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LZI70_10730	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LZI70_10740	COG2233	PERMEase
LZI70_10760	COG1393	Belongs to the ArsC family
LZI70_10765	COG4783	chaperone-mediated protein folding
LZI70_10780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LZI70_10785	COG2716	regulation of RNA biosynthetic process
LZI70_10790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LZI70_10795	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LZI70_10805	COG1876	peptidase activity
LZI70_10810	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZI70_10815	COG1393	Belongs to the ArsC family
LZI70_10840	COG2837	iron assimilation
LZI70_10845	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LZI70_10850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LZI70_10855	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LZI70_10860	COG2190	(PTS) system
LZI70_10865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LZI70_10870	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZI70_10880	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LZI70_10885	COG3115	cell septum assembly
LZI70_10890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LZI70_10905	COG0789	Transcriptional regulator
LZI70_10915	COG0330	HflC and HflK could
LZI70_10920	COG3118	belongs to the thioredoxin family
LZI70_10925	COG0300	oxidoreductase activity
LZI70_10930	COG1090	epimerase
LZI70_10955	COG0622	Phosphoesterase
LZI70_10970	COG3710	Transcriptional regulator
LZI70_10975	COG0326	Molecular chaperone. Has ATPase activity
LZI70_10980	COG0563	adenylate kinase activity
LZI70_10985	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LZI70_10990	COG3104	oligopeptide transport
LZI70_10995	COG0250	Participates in transcription elongation, termination and antitermination
LZI70_11000	COG0367	asparagine synthase
LZI70_11005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LZI70_11005	COG4651	solute:proton antiporter activity
LZI70_11010	COG1846	Transcriptional regulator
LZI70_11010	COG1940	carbohydrate kinase activity
LZI70_11015	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LZI70_11020	COG1263	PTS System
LZI70_11020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LZI70_11020	COG2190	(PTS) system
LZI70_11025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LZI70_11050	COG0596	Alpha beta hydrolase
LZI70_11055	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LZI70_11060	COG0033	Phosphoglucomutase
LZI70_11070	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LZI70_11085	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LZI70_11090	COG1053	succinate dehydrogenase
LZI70_11095	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LZI70_11100	COG0567	Dehydrogenase, E1 component
LZI70_11105	COG0508	dehydrogenase complex catalyzes the overall conversion of
LZI70_11110	COG0045	succinate-CoA ligase (ADP-forming) activity
LZI70_11120	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LZI70_11125	COG1121	(ABC) transporter
LZI70_11130	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LZI70_11140	COG1918	ferrous iron import across plasma membrane
LZI70_11165	COG3102	Protein conserved in bacteria
LZI70_11170	COG0788	formyltetrahydrofolate deformylase activity
LZI70_11175	COG1199	ATP-dependent helicase activity
LZI70_11180	COG1214	PFAM Peptidase M22, glycoprotease
LZI70_11190	COG3065	identical protein binding
LZI70_11195	COG0596	Alpha beta hydrolase
LZI70_11200	COG0318	PFAM AMP-dependent synthetase and ligase
LZI70_11205	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LZI70_11210	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LZI70_11215	COG2894	cell division
LZI70_11220	COG0850	regulation of cytokinetic process
LZI70_11225	COG3100	YcgL domain-containing protein
LZI70_11230	COG2951	lytic endotransglycosylase activity
LZI70_11240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LZI70_11245	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LZI70_11285	COG0515	serine threonine protein kinase
LZI70_11285	COG2815	serine threonine protein kinase
LZI70_11300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LZI70_11305	COG2860	membrane
LZI70_11310	COG3101	peptidyl-lysine hydroxylation
LZI70_11320	COG0431	NADPH-dependent FMN reductase
LZI70_11330	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LZI70_11335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LZI70_11340	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZI70_11350	COG0101	tRNA pseudouridine synthase activity
LZI70_11355	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LZI70_11360	COG0285	dihydrofolate synthase activity
LZI70_11365	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LZI70_11370	COG1286	toxin biosynthetic process
LZI70_11375	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LZI70_11380	COG0583	DNA-binding transcription factor activity
LZI70_11385	COG0745	RESPONSE REGULATOR receiver
LZI70_11395	COG2832	Protein of unknown function (DUF454)
LZI70_11400	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LZI70_11405	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LZI70_11415	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LZI70_11425	COG2983	Belongs to the UPF0260 family
LZI70_11430	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LZI70_11535	COG4695	Portal protein
LZI70_11585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LZI70_11680	COG2226	methyltransferase
LZI70_11695	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LZI70_11705	COG3139	Protein of unknown function (DUF1315)
LZI70_11710	COG0252	asparaginase activity
LZI70_11715	COG0616	signal peptide processing
LZI70_11720	COG1902	pentaerythritol trinitrate reductase activity
LZI70_11720	COG0446	pyridine nucleotide-disulphide oxidoreductase
LZI70_11725	COG0778	Nitroreductase
LZI70_11730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LZI70_11740	COG0123	including yeast histone deacetylase and acetoin utilization protein
LZI70_11755	COG3083	sulfuric ester hydrolase activity
LZI70_11760	COG3082	Protein of unknown function (DUF1414)
LZI70_11765	COG3081	Nucleoid-associated protein
LZI70_11775	COG1757	Na H antiporter
LZI70_11780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LZI70_11785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LZI70_11790	COG2095	MarC family integral membrane protein
LZI70_11795	COG1012	belongs to the aldehyde dehydrogenase family
LZI70_11795	COG1454	alcohol dehydrogenase
LZI70_11805	COG2205	protein histidine kinase activity
LZI70_11805	COG0784	Response regulator, receiver
LZI70_11815	COG2197	response regulator
LZI70_11820	COG3706	GGDEF domain
LZI70_11825	COG0583	DNA-binding transcription factor activity
LZI70_11835	COG0840	transmembrane signaling receptor activity
LZI70_11855	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LZI70_11865	COG2056	Na+-H+ antiporter family
LZI70_11875	COG2885	chlorophyll binding
LZI70_11885	COG0346	lactoylglutathione lyase activity
LZI70_11890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LZI70_11895	COG4660	Part of a membrane complex involved in electron transport
LZI70_11900	COG4659	FMN binding
LZI70_11905	COG4658	electron transport chain
LZI70_11910	COG4656	Part of a membrane complex involved in electron transport
LZI70_11915	COG2878	Part of a membrane complex involved in electron transport
LZI70_11920	COG4657	Part of a membrane complex involved in electron transport
LZI70_11930	COG0556	nucleotide-excision repair
LZI70_11935	COG2204	response regulator
LZI70_11940	COG2198	Histidine kinase
LZI70_11945	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LZI70_11950	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LZI70_11955	COG0521	Mo-molybdopterin cofactor biosynthetic process
LZI70_11960	COG0315	cyclic pyranopterin monophosphate synthase activity
LZI70_11965	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LZI70_11970	COG0314	molybdopterin synthase activity
LZI70_11980	COG0601	transmembrane transport
LZI70_11985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LZI70_11990	COG0444	Belongs to the ABC transporter superfamily
LZI70_12000	COG0435	Glutathione S-transferase
LZI70_12005	COG0280	phosphate acetyltransferase
LZI70_12005	COG0857	belongs to the CobB CobQ family
LZI70_12015	COG3092	negative regulation of chromosome organization
LZI70_12025	COG0366	Alpha amylase catalytic
LZI70_12030	COG3706	GGDEF domain
LZI70_12035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LZI70_12040	COG2165	general secretion pathway protein
LZI70_12055	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LZI70_12060	COG2186	Transcriptional regulator
LZI70_12070	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZI70_12070	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZI70_12075	COG0489	protein tyrosine kinase activity
LZI70_12080	COG0572	uridine kinase
LZI70_12085	COG2982	Protein involved in outer membrane biogenesis
LZI70_12090	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LZI70_12095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LZI70_12100	COG0659	secondary active sulfate transmembrane transporter activity
LZI70_12105	COG1530	ribonuclease E activity
LZI70_12110	COG0564	pseudouridine synthase activity
LZI70_12115	COG0424	maF-like protein
LZI70_12120	COG1399	metal-binding, possibly nucleic acid-binding protein
LZI70_12125	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LZI70_12130	COG0416	fatty acid biosynthetic process
LZI70_12135	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZI70_12160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LZI70_12165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LZI70_12170	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LZI70_12175	COG0470	DNA polymerase III
LZI70_12180	COG0084	hydrolase, TatD family'
LZI70_12185	COG1263	PTS System
LZI70_12185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LZI70_12200	COG4667	esterase of the alpha-beta hydrolase superfamily
LZI70_12205	COG0469	pyruvate kinase activity
LZI70_12210	COG1940	carbohydrate kinase activity
LZI70_12215	COG0784	Response regulator, receiver
LZI70_12215	COG0835	chemotaxis
LZI70_12220	COG0587	DNA-directed DNA polymerase activity
LZI70_12235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LZI70_12245	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LZI70_12255	COG4591	ABC-type transport system involved in lipoprotein release permease component
LZI70_12260	COG1136	(ABC) transporter
LZI70_12265	COG4591	ABC-type transport system involved in lipoprotein release permease component
LZI70_12275	COG0658	competence protein
LZI70_12275	COG2333	competence protein COMEC
LZI70_12280	COG1132	(ABC) transporter
LZI70_12285	COG1663	tetraacyldisaccharide 4'-kinase activity
LZI70_12290	COG2835	tetraacyldisaccharide 4'-kinase activity
LZI70_12295	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LZI70_12300	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LZI70_12305	COG0539	negative regulation of cytoplasmic translation
LZI70_12310	COG0776	regulation of translation
LZI70_12315	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LZI70_12320	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LZI70_12325	COG0284	orotidine-5'-phosphate decarboxylase activity
LZI70_12330	COG0601	transmembrane transport
LZI70_12335	COG4239	(ABC) transporter, permease
LZI70_12340	COG4166	transmembrane transport
LZI70_12345	COG0444	Belongs to the ABC transporter superfamily
LZI70_12350	COG4608	Belongs to the ABC transporter superfamily
LZI70_12375	COG0583	DNA-binding transcription factor activity
LZI70_12385	COG0686	Belongs to the AlaDH PNT family
LZI70_12390	COG1522	sequence-specific DNA binding
LZI70_12395	COG1674	ftsk spoiiie
LZI70_12400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LZI70_12405	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LZI70_12410	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LZI70_12415	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LZI70_12420	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LZI70_12425	COG0156	8-amino-7-oxononanoate synthase activity
LZI70_12430	COG2226	methyltransferase
LZI70_12445	COG0501	Belongs to the peptidase M48B family
LZI70_12450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LZI70_12455	COG2915	High frequency lysogenization protein hflD homolog
LZI70_12470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZI70_12475	COG2916	Histone family protein nucleoid-structuring protein H-NS
LZI70_12480	COG1757	Na H antiporter
LZI70_12500	COG0131	Imidazoleglycerol-phosphate dehydratase
LZI70_12500	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LZI70_12505	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LZI70_12510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LZI70_12520	COG0140	phosphoribosyl-ATP diphosphatase activity
LZI70_12520	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LZI70_12525	COG3012	SEC-C Motif Domain Protein
LZI70_12530	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LZI70_12535	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LZI70_12540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LZI70_12545	COG0215	cysteine-tRNA ligase activity
LZI70_12575	COG2116	formate transmembrane transporter activity
LZI70_12580	COG0390	transport system, permease component
LZI70_12585	COG4459	periplasmic nitrate reductase
LZI70_12590	COG3005	denitrification pathway
LZI70_12595	COG0243	molybdopterin cofactor binding
LZI70_12605	COG1227	inorganic diphosphatase activity
LZI70_12620	COG4172	Belongs to the ABC transporter superfamily
LZI70_12630	COG4171	peptide transport system, permease
LZI70_12645	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LZI70_12650	COG1842	Phage shock protein A
LZI70_12660	COG1983	PspC domain protein
LZI70_12680	COG2818	Glycosylase
LZI70_12685	COG0626	cystathionine gamma-synthase activity
LZI70_12695	COG0733	neurotransmitter:sodium symporter activity
LZI70_12700	COG0564	pseudouridine synthase activity
LZI70_12705	COG0116	Belongs to the methyltransferase superfamily
LZI70_12705	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LZI70_12710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LZI70_12715	COG4136	ATPase activity
LZI70_12720	COG4135	transport system, permease component
LZI70_12725	COG4134	Bacterial extracellular solute-binding protein
LZI70_12735	COG3313	Fe-S protein
LZI70_12750	COG0513	Belongs to the DEAD box helicase family
LZI70_12760	COG2866	Carboxypeptidase
LZI70_12775	COG4774	siderophore transport
LZI70_12795	COG0583	DNA-binding transcription factor activity
LZI70_12805	COG1511	domain protein
LZI70_12805	COG3264	Mechanosensitive ion channel
LZI70_12820	COG0384	phenazine biosynthesis protein PhzF
LZI70_12880	COG2944	sequence-specific DNA binding
LZI70_12885	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LZI70_12890	COG0463	Glycosyl transferase, family 2
LZI70_12890	COG1216	Glycosyl transferase, family 2
LZI70_12900	COG2205	protein histidine kinase activity
LZI70_12915	COG1061	Type III restriction enzyme res subunit
LZI70_12925	COG2814	Major facilitator Superfamily
LZI70_12935	COG0702	epimerase
LZI70_12940	COG0534	Mate efflux family protein
LZI70_12945	COG4181	ATPase activity
LZI70_12960	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LZI70_12980	COG1960	acyl-CoA dehydrogenase activity
LZI70_12990	COG3273	potassium ion transport
LZI70_12990	COG2985	domain, Protein
LZI70_12995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LZI70_13005	COG1737	Transcriptional regulator
LZI70_13010	COG0076	glutamate decarboxylase activity
LZI70_13020	COG2431	L-lysine efflux transmembrane transporter activity
LZI70_13030	COG3070	regulator of competence-specific genes
LZI70_13045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LZI70_13045	COG4191	Histidine kinase
LZI70_13055	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LZI70_13075	COG1448	Aminotransferase
LZI70_13080	COG2770	Histidine kinase
LZI70_13080	COG3437	response regulator, receiver
LZI70_13090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LZI70_13100	COG0017	Asparaginyl-tRNA synthetase
LZI70_13105	COG0840	transmembrane signaling receptor activity
LZI70_13115	COG0814	amino acid
LZI70_13120	COG1760	l-serine dehydratase
LZI70_13125	COG0814	amino acid
LZI70_13130	COG0494	nUDIX hydrolase
LZI70_13140	COG2205	protein histidine kinase activity
LZI70_13140	COG0784	Response regulator, receiver
LZI70_13145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LZI70_13160	COG3106	COG3106 Predicted ATPase
LZI70_13165	COG3768	UPF0283 membrane protein
LZI70_13175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LZI70_13190	COG0443	Heat shock 70 kDa protein
LZI70_13245	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LZI70_13250	COG1643	Atp-dependent helicase
LZI70_13295	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LZI70_13300	COG0072	phenylalanine-tRNA ligase activity
LZI70_13300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LZI70_13320	COG0596	Alpha beta hydrolase
LZI70_13335	COG1464	Belongs to the NlpA lipoprotein family
LZI70_13360	COG1121	(ABC) transporter
LZI70_13365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LZI70_13370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LZI70_13380	COG0776	regulation of translation
LZI70_13390	COG0500	methyltransferase
LZI70_13395	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LZI70_13400	COG0295	cytidine deaminase activity
LZI70_13405	COG1346	cytolysis
LZI70_13415	COG2925	Exonuclease
LZI70_13430	COG2207	Transcriptional regulator
LZI70_13435	COG3122	Protein conserved in bacteria
LZI70_13440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LZI70_13455	COG4989	oxidoreductase activity
LZI70_13465	COG1823	symporter activity
LZI70_13470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LZI70_13475	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LZI70_13480	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LZI70_13500	COG2988	succinylglutamate desuccinylase activity
LZI70_13505	COG4139	cobalamin transport
LZI70_13510	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
LZI70_13515	COG1247	-acetyltransferase
LZI70_13530	COG2814	Major facilitator Superfamily
LZI70_13545	COG1451	nucleotide metabolic process
LZI70_13555	COG3063	Type IV pilus biogenesis stability protein PilW
LZI70_13560	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LZI70_13575	COG2195	Cleaves the N-terminal amino acid of tripeptides
LZI70_13665	COG4628	conserved protein (DUF2132)
LZI70_13700	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LZI70_13705	COG0372	Belongs to the citrate synthase family
LZI70_13710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LZI70_13715	COG2828	Protein conserved in bacteria
LZI70_13735	COG0561	phosphatase activity
LZI70_13740	COG0602	queuosine metabolic process
LZI70_13745	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LZI70_13760	COG3047	cAMP biosynthetic process
LZI70_13760	COG2885	chlorophyll binding
LZI70_13780	COG4608	Belongs to the ABC transporter superfamily
LZI70_13785	COG0444	Belongs to the ABC transporter superfamily
LZI70_13795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LZI70_13795	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
LZI70_13815	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LZI70_13825	COG0625	glutathione transferase activity
LZI70_13830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LZI70_13835	COG3186	Phenylalanine-4-hydroxylase
LZI70_13850	COG0217	transcriptional regulatory protein
LZI70_13865	COG2084	Dehydrogenase
LZI70_13880	COG1136	(ABC) transporter
LZI70_13880	COG0577	efflux transmembrane transporter activity
LZI70_13900	COG3275	phosphorelay sensor kinase activity
LZI70_13905	COG3279	Response regulator of the LytR AlgR family
LZI70_13910	COG0612	Peptidase, M16
LZI70_13920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZI70_13925	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LZI70_13945	COG1902	pentaerythritol trinitrate reductase activity
LZI70_13970	COG3634	alkyl hydroperoxide reductase activity
LZI70_13975	COG0450	alkyl hydroperoxide reductase
LZI70_13995	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LZI70_14010	COG0300	oxidoreductase activity
LZI70_14020	COG0415	Belongs to the DNA photolyase family
LZI70_14030	COG3806	Anti-sigma factor
LZI70_14035	COG1595	DNA-templated transcription, initiation
LZI70_14055	COG0786	glutamate:sodium symporter activity
LZI70_14070	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZI70_14070	COG2213	PTS system mannitol-specific
LZI70_14075	COG0246	Mannitol dehydrogenase
LZI70_14080	COG3722	fumarate hydratase activity
LZI70_14085	COG0363	glucosamine-6-phosphate deaminase activity
LZI70_14105	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
LZI70_14120	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LZI70_14125	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LZI70_14155	COG0596	Alpha beta hydrolase
LZI70_14170	COG3123	guanosine phosphorylase activity
LZI70_14175	COG1741	Belongs to the pirin family
LZI70_14205	COG1054	Belongs to the UPF0176 family
LZI70_14215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LZI70_14220	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LZI70_14220	COG2207	Transcriptional regulator
LZI70_14230	COG1304	FMN binding
LZI70_14235	COG1620	l-lactate permease
LZI70_14240	COG0583	DNA-binding transcription factor activity
LZI70_14245	COG1505	serine-type exopeptidase activity
LZI70_14250	COG4172	Belongs to the ABC transporter superfamily
LZI70_14260	COG1067	ATP-dependent peptidase activity
LZI70_14290	COG1846	Transcriptional regulator
LZI70_14300	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LZI70_14305	COG3960	tartronate-semialdehyde synthase activity
LZI70_14310	COG3622	Belongs to the hyi family
LZI70_14315	COG2084	Dehydrogenase
LZI70_14340	COG2252	PERMEase
LZI70_14360	COG4266	Belongs to the allantoicase family
LZI70_14365	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LZI70_14380	COG0402	S-adenosylhomocysteine deaminase activity
LZI70_14390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LZI70_14400	COG2186	Transcriptional regulator
LZI70_14410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZI70_14415	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LZI70_14425	COG0625	glutathione transferase activity
LZI70_14430	COG0583	DNA-binding transcription factor activity
LZI70_14435	COG3284	Transcriptional regulator
LZI70_14440	COG1012	belongs to the aldehyde dehydrogenase family
LZI70_14470	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LZI70_14480	COG2200	EAL domain
LZI70_14485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LZI70_14500	COG0583	DNA-binding transcription factor activity
LZI70_14525	COG0546	phosphoglycolate phosphatase activity
LZI70_14530	COG3842	ATPase activity
LZI70_14555	COG0840	transmembrane signaling receptor activity
LZI70_14560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LZI70_14575	COG0840	transmembrane signaling receptor activity
LZI70_14585	COG0583	DNA-binding transcription factor activity
LZI70_14600	COG4191	Histidine kinase
LZI70_14605	COG2204	response regulator
LZI70_14620	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LZI70_14625	COG3639	organic phosphonate transmembrane transporter activity
LZI70_14630	COG3639	organic phosphonate transmembrane transporter activity
LZI70_14645	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LZI70_14650	COG3047	cAMP biosynthetic process
LZI70_14655	COG2358	TRAP transporter, solute receptor (TAXI family
LZI70_14665	COG1022	Amp-dependent synthetase and ligase
LZI70_14670	COG5001	Diguanylate cyclase
LZI70_14670	COG4251	negative regulation of phosphorylation
LZI70_14670	COG3706	GGDEF domain
LZI70_14670	COG2203	Gaf domain
LZI70_14675	COG4221	oxidoreductase activity
LZI70_14690	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LZI70_14710	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LZI70_14720	COG1901	pseudouridine methyltransferase
LZI70_14775	COG0534	Mate efflux family protein
LZI70_14785	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LZI70_14790	COG2999	glutathione oxidoreductase activity
LZI70_14800	COG0673	inositol 2-dehydrogenase activity
LZI70_14815	COG0584	glycerophosphoryl diester phosphodiesterase
LZI70_14830	COG4067	protein conserved in archaea
LZI70_14830	COG0189	ligase activity
LZI70_14835	COG0189	ligase activity
LZI70_14860	COG0564	pseudouridine synthase activity
LZI70_14885	COG1131	(ABC) transporter
LZI70_14890	COG2186	Transcriptional regulator
LZI70_14900	COG5001	Diguanylate cyclase
LZI70_14905	COG0745	RESPONSE REGULATOR receiver
LZI70_14910	COG2205	protein histidine kinase activity
LZI70_14915	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LZI70_14920	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LZI70_14930	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LZI70_14955	COG0513	Belongs to the DEAD box helicase family
LZI70_14970	COG3706	GGDEF domain
LZI70_14975	COG1278	Cold shock
LZI70_14980	COG0402	S-adenosylhomocysteine deaminase activity
LZI70_14985	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LZI70_14990	COG1566	PFAM secretion protein HlyD family protein
LZI70_15015	COG0531	amino acid
LZI70_15040	COG1151	hydroxylamine reductase activity
LZI70_15045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LZI70_15060	COG2926	Belongs to the UPF0265 family
LZI70_15070	COG3132	Protein of unknown function, DUF480
LZI70_15075	COG2827	Endonuclease containing a URI domain
LZI70_15080	COG1879	ABC-type sugar transport system periplasmic component
LZI70_15085	COG0784	Response regulator, receiver
LZI70_15085	COG2205	protein histidine kinase activity
LZI70_15105	COG0443	Heat shock 70 kDa protein
LZI70_15110	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LZI70_15115	COG0179	Fumarylacetoacetate (FAA) hydrolase
LZI70_15120	COG1280	lysine exporter protein (LysE YggA)
LZI70_15125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LZI70_15130	COG1565	acr, cog1565
LZI70_15130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LZI70_15145	COG1845	cytochrome c oxidase, subunit III
LZI70_15170	COG0109	protoheme IX farnesyltransferase activity
LZI70_15180	COG3530	Putative quorum-sensing-regulated virulence factor
LZI70_15190	COG1028	Short-chain dehydrogenase reductase Sdr
LZI70_15200	COG3152	Membrane
LZI70_15210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LZI70_15215	COG0668	transmembrane transport
LZI70_15220	COG0569	domain protein
LZI70_15225	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LZI70_15230	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LZI70_15230	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LZI70_15235	COG1765	OsmC-like protein
LZI70_15240	COG3047	cAMP biosynthetic process
LZI70_15240	COG2885	chlorophyll binding
LZI70_15250	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LZI70_15255	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LZI70_15260	COG1840	ABC-type Fe3 transport system, periplasmic component
LZI70_15265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZI70_15270	COG1629	transport
LZI70_15275	COG3842	ATPase activity
LZI70_15285	COG2188	Transcriptional regulator
LZI70_15295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LZI70_15305	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LZI70_15305	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LZI70_15310	COG3265	gluconokinase activity
LZI70_15315	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LZI70_15320	COG1609	Transcriptional regulator
LZI70_15330	COG1760	l-serine dehydratase
LZI70_15345	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LZI70_15355	COG1132	(ABC) transporter
LZI70_15360	COG1132	(ABC) transporter
LZI70_15380	COG0393	Putative heavy-metal-binding
LZI70_15395	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LZI70_15415	COG0346	lactoylglutathione lyase activity
LZI70_15425	COG2211	Major facilitator Superfamily
LZI70_15430	COG0156	8-amino-7-oxononanoate synthase activity
LZI70_15435	COG1063	alcohol dehydrogenase
LZI70_15440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LZI70_15440	COG3153	acetyltransferase
LZI70_15460	COG2249	NAD(P)H dehydrogenase (quinone) activity
LZI70_15480	COG1454	alcohol dehydrogenase
LZI70_15490	COG1011	Hydrolase
LZI70_15510	COG2264	protein methyltransferase activity
LZI70_15515	COG1328	CTP reductase activity
LZI70_15520	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LZI70_15555	COG2026	Addiction module toxin, RelE StbE family
LZI70_15575	COG0583	DNA-binding transcription factor activity
LZI70_15595	COG1289	transmembrane transporter activity
LZI70_15600	COG0210	DNA helicase
LZI70_15610	COG1803	Methylglyoxal synthase
LZI70_15615	COG1879	ABC-type sugar transport system periplasmic component
LZI70_15620	COG2198	Histidine kinase
LZI70_15620	COG2205	protein histidine kinase activity
LZI70_15620	COG0784	Response regulator, receiver
LZI70_15630	COG1629	transport
LZI70_15665	COG0625	glutathione transferase activity
LZI70_15675	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LZI70_15675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZI70_15675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LZI70_15680	COG1105	Belongs to the carbohydrate kinase PfkB family
LZI70_15685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZI70_15685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LZI70_15690	COG1609	Transcriptional regulator
LZI70_15695	COG0515	serine threonine protein kinase
LZI70_15695	COG2815	serine threonine protein kinase
LZI70_15700	COG2223	nitrite transmembrane transporter activity
LZI70_15710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LZI70_15710	COG2146	nitrite reductase [NAD(P)H] activity
LZI70_15715	COG0243	molybdopterin cofactor binding
LZI70_15760	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
LZI70_15805	COG1280	lysine exporter protein (LysE YggA)
LZI70_15880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LZI70_15890	COG0583	DNA-binding transcription factor activity
LZI70_15900	COG2205	protein histidine kinase activity
LZI70_15900	COG0784	Response regulator, receiver
LZI70_15905	COG1609	Transcriptional regulator
LZI70_15910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZI70_15915	COG1879	ABC-type sugar transport system periplasmic component
LZI70_15920	COG1172	Belongs to the binding-protein-dependent transport system permease family
LZI70_15925	COG1129	ABC transporter
LZI70_15930	COG1869	D-ribose catabolic process
LZI70_15940	COG4166	transmembrane transport
LZI70_15945	COG4174	ABC transporter (Permease)
LZI70_15950	COG4239	(ABC) transporter, permease
LZI70_15955	COG4172	Belongs to the ABC transporter superfamily
LZI70_15960	COG4174	ABC transporter (Permease)
LZI70_15965	COG4239	(ABC) transporter, permease
LZI70_15970	COG4166	transmembrane transport
LZI70_15975	COG0444	Belongs to the ABC transporter superfamily
LZI70_15980	COG4608	Belongs to the ABC transporter superfamily
LZI70_15995	COG0745	RESPONSE REGULATOR receiver
LZI70_16000	COG0642	Histidine kinase
LZI70_16020	COG0583	DNA-binding transcription factor activity
LZI70_16030	COG1012	belongs to the aldehyde dehydrogenase family
LZI70_16040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LZI70_16075	COG3278	Belongs to the heme-copper respiratory oxidase family
LZI70_16085	COG0454	-acetyltransferase
LZI70_16090	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LZI70_16095	COG5002	protein histidine kinase activity
LZI70_16095	COG0784	Response regulator, receiver
LZI70_16095	COG2198	Histidine kinase
LZI70_16100	COG2205	protein histidine kinase activity
LZI70_16100	COG0784	Response regulator, receiver
LZI70_16110	COG3119	arylsulfatase activity
LZI70_16115	COG0457	Tetratricopeptide repeat
LZI70_16120	COG0714	Associated with various cellular activities
LZI70_16165	COG5002	protein histidine kinase activity
LZI70_16165	COG2205	protein histidine kinase activity
LZI70_16165	COG0784	Response regulator, receiver
LZI70_16185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZI70_16205	COG0745	RESPONSE REGULATOR receiver
LZI70_16210	COG1366	Belongs to the anti-sigma-factor antagonist family
LZI70_16215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LZI70_16300	COG1028	Short-chain dehydrogenase reductase Sdr
LZI70_16310	COG1288	antiporter activity
LZI70_16320	COG2165	general secretion pathway protein
LZI70_16325	COG1280	lysine exporter protein (LysE YggA)
LZI70_16335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LZI70_16345	COG2116	formate transmembrane transporter activity
LZI70_16350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LZI70_16350	COG1648	precorrin-2 dehydrogenase activity
LZI70_16365	COG0745	RESPONSE REGULATOR receiver
LZI70_16370	COG2205	protein histidine kinase activity
LZI70_16375	COG1301	dicarboxylic acid transport
LZI70_16390	COG0811	peptide transport
LZI70_16395	COG0811	peptide transport
LZI70_16400	COG0848	biopolymer transport protein
LZI70_16440	COG0803	Belongs to the bacterial solute-binding protein 9 family
LZI70_16445	COG1121	(ABC) transporter
LZI70_16450	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LZI70_16470	COG0534	Mate efflux family protein
LZI70_16490	COG3118	belongs to the thioredoxin family
LZI70_16495	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LZI70_16510	COG1328	CTP reductase activity
LZI70_16515	COG0602	queuosine metabolic process
LZI70_16520	COG0534	Mate efflux family protein
LZI70_16535	COG0189	ligase activity
LZI70_16535	COG4067	protein conserved in archaea
LZI70_16555	COG0725	ABC transporter, periplasmic molybdate-binding protein
LZI70_16560	COG4149	molybdate abc transporter
LZI70_16565	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LZI70_16575	COG2203	Gaf domain
LZI70_16575	COG5001	Diguanylate cyclase
LZI70_16575	COG4251	negative regulation of phosphorylation
LZI70_16575	COG3706	GGDEF domain
LZI70_16585	COG3706	GGDEF domain
LZI70_16600	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LZI70_16605	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LZI70_16630	COG3140	Belongs to the UPF0181 family
LZI70_16640	COG0023	Translation Initiation Factor
LZI70_16655	COG1181	Belongs to the D-alanine--D-alanine ligase family
LZI70_16665	COG0045	succinate-CoA ligase (ADP-forming) activity
LZI70_16665	COG1042	CoA-binding domain protein
LZI70_16665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LZI70_16670	COG0583	DNA-binding transcription factor activity
LZI70_16680	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LZI70_16690	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LZI70_16695	COG1984	allophanate hydrolase subunit 2
LZI70_16700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZI70_16700	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LZI70_16705	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LZI70_16710	COG4181	ATPase activity
LZI70_16720	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LZI70_16725	COG1716	ATPase activity
LZI70_16725	COG5001	Diguanylate cyclase
LZI70_16760	COG4533	DNA binding
LZI70_16770	COG2050	protein possibly involved in aromatic compounds catabolism
LZI70_16785	COG2067	long-chain fatty acid transport protein
LZI70_16790	COG2267	carboxylic ester hydrolase activity
LZI70_16805	COG0583	DNA-binding transcription factor activity
LZI70_16820	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LZI70_16830	COG2985	domain, Protein
LZI70_16840	COG1566	PFAM secretion protein HlyD family protein
LZI70_16855	COG2272	Belongs to the type-B carboxylesterase lipase family
LZI70_16860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZI70_16865	COG0729	surface antigen
LZI70_16870	COG0513	Belongs to the DEAD box helicase family
LZI70_16880	COG0861	Integral membrane protein TerC family
LZI70_16885	COG0737	Belongs to the 5'-nucleotidase family
LZI70_16890	COG3593	DNA synthesis involved in DNA repair
LZI70_16900	COG0583	DNA-binding transcription factor activity
LZI70_16905	COG2116	formate transmembrane transporter activity
LZI70_16915	COG3038	cytochrome b561
LZI70_16930	COG2200	EAL domain
LZI70_16945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZI70_16955	COG0513	Belongs to the DEAD box helicase family
LZI70_16960	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LZI70_16965	COG0814	amino acid
LZI70_16970	COG0840	transmembrane signaling receptor activity
LZI70_16975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZI70_16990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZI70_16995	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LZI70_17005	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LZI70_17040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LZI70_17045	COG0509	glycine decarboxylation via glycine cleavage system
LZI70_17070	COG0277	FAD linked oxidase domain protein
LZI70_17075	COG0583	DNA-binding transcription factor activity
LZI70_17130	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LZI70_17140	COG0494	nUDIX hydrolase
LZI70_17145	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LZI70_17150	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LZI70_17155	COG0456	acetyltransferase
LZI70_17155	COG1214	PFAM Peptidase M22, glycoprotease
LZI70_17165	COG0840	transmembrane signaling receptor activity
LZI70_17170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZI70_17175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LZI70_17185	COG2267	carboxylic ester hydrolase activity
LZI70_17190	COG0745	RESPONSE REGULATOR receiver
LZI70_17200	COG3069	C4-dicarboxylate transmembrane transporter activity
LZI70_17205	COG2197	response regulator
LZI70_17210	COG3850	Histidine kinase
LZI70_17225	COG0243	molybdopterin cofactor binding
LZI70_17255	COG0183	Belongs to the thiolase family
LZI70_17300	COG0745	RESPONSE REGULATOR receiver
LZI70_17325	COG1280	lysine exporter protein (LysE YggA)
LZI70_17330	COG0513	Belongs to the DEAD box helicase family
LZI70_17335	COG0523	cobalamin synthesis protein
LZI70_17340	COG0038	chloride channel
LZI70_17350	COG1017	nitric oxide dioxygenase activity
LZI70_17350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LZI70_17355	COG3604	Transcriptional regulator
LZI70_17375	COG0545	Peptidyl-prolyl cis-trans isomerase
LZI70_17380	COG1309	transcriptional regulator
LZI70_17385	COG2130	NADP-dependent
LZI70_17395	COG0564	pseudouridine synthase activity
LZI70_17400	COG1686	Belongs to the peptidase S11 family
LZI70_17415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LZI70_17430	COG2207	Transcriptional regulator
LZI70_17435	COG1979	alcohol dehydrogenase
LZI70_17460	COG4206	TonB-dependent receptor
LZI70_17465	COG4977	sequence-specific DNA binding
LZI70_17485	COG1716	ATPase activity
LZI70_17485	COG5001	Diguanylate cyclase
LZI70_17490	COG0784	Response regulator, receiver
LZI70_17490	COG2205	protein histidine kinase activity
LZI70_17495	COG0840	transmembrane signaling receptor activity
LZI70_17500	COG0471	metal ion transport
LZI70_17500	COG3273	potassium ion transport
LZI70_17510	COG1024	Enoyl-CoA hydratase
LZI70_17515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LZI70_17540	COG2814	Major facilitator Superfamily
LZI70_17545	COG2133	pyrroloquinoline quinone binding
LZI70_17550	COG1278	Cold shock
LZI70_17555	COG4681	YaeQ
LZI70_17565	COG0302	gtp cyclohydrolase
LZI70_17595	COG2897	thiosulfate sulfurtransferase activity
LZI70_17615	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LZI70_17620	COG0840	transmembrane signaling receptor activity
LZI70_17625	COG1560	Kdo2-lipid A biosynthetic process
LZI70_17630	COG2814	Major facilitator Superfamily
LZI70_17635	COG0583	DNA-binding transcription factor activity
LZI70_17640	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZI70_17650	COG2186	Transcriptional regulator
LZI70_17655	COG2186	Transcriptional regulator
LZI70_17670	COG4604	ABC transporter, ATP-binding protein
LZI70_17675	COG4605	iron ion homeostasis
LZI70_17680	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LZI70_17685	COG4607	ABC-type enterochelin transport system periplasmic component
LZI70_17705	COG1917	Cupin 2, conserved barrel domain protein
LZI70_17710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZI70_17715	COG0800	Aldolase
LZI70_17720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZI70_17735	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LZI70_17760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LZI70_17765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LZI70_17770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LZI70_17775	COG1116	anion transmembrane transporter activity
LZI70_17780	COG0351	phosphomethylpyrimidine kinase
LZI70_17800	COG0348	domain, Protein
LZI70_17805	COG0437	4 iron, 4 sulfur cluster binding
LZI70_17880	COG0183	Belongs to the thiolase family
LZI70_17890	COG0427	acetyl-CoA hydrolase
LZI70_17895	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LZI70_17920	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LZI70_17925	COG0516	GMP reductase activity
LZI70_17945	COG0534	Mate efflux family protein
LZI70_17950	COG0583	DNA-binding transcription factor activity
LZI70_17955	COG0840	transmembrane signaling receptor activity
LZI70_17960	COG0840	transmembrane signaling receptor activity
LZI70_17965	COG3135	benzoate transporter
LZI70_17970	COG1396	sequence-specific DNA binding
LZI70_17980	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LZI70_17985	COG0513	Belongs to the DEAD box helicase family
LZI70_17990	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LZI70_18005	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LZI70_18035	COG2195	Cleaves the N-terminal amino acid of tripeptides
LZI70_18045	COG0667	Aldo Keto reductase
LZI70_18050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LZI70_18055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LZI70_18060	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LZI70_18065	COG0513	Belongs to the DEAD box helicase family
LZI70_18070	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LZI70_18085	COG0513	Belongs to the DEAD box helicase family
LZI70_18090	COG4989	oxidoreductase activity
LZI70_18105	COG0668	transmembrane transport
LZI70_18120	COG4232	protein-disulfide reductase activity
LZI70_18125	COG3118	belongs to the thioredoxin family
LZI70_18130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LZI70_18130	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LZI70_18145	COG0697	spore germination
LZI70_18160	COG2814	Major facilitator Superfamily
LZI70_18165	COG0583	DNA-binding transcription factor activity
LZI70_18170	COG5001	Diguanylate cyclase
LZI70_18175	COG0739	heme binding
LZI70_18200	COG3314	Sporulation integral membrane protein YlbJ
LZI70_18210	COG0366	Alpha amylase catalytic
LZI70_18215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LZI70_18220	COG0784	Response regulator, receiver
LZI70_18220	COG0835	chemotaxis
LZI70_18225	COG2096	Adenosyltransferase
LZI70_18230	COG0748	coenzyme F420 binding
LZI70_18235	COG3721	Heme iron utilization protein
LZI70_18240	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LZI70_18245	COG0811	peptide transport
LZI70_18250	COG0848	biopolymer transport protein
LZI70_18260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LZI70_18265	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LZI70_18315	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LZI70_18320	COG0633	Ferredoxin
LZI70_18320	COG3217	Mosc domain protein beta barrel domain protein
LZI70_18325	COG0401	homolog of Blt101
LZI70_18330	COG0418	dihydroorotase activity
LZI70_18345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LZI70_18350	COG0583	DNA-binding transcription factor activity
LZI70_18365	COG0312	modulator of DNA gyrase
LZI70_18370	COG0312	modulator of DNA gyrase
LZI70_18380	COG1136	(ABC) transporter
LZI70_18385	COG0577	efflux transmembrane transporter activity
LZI70_18415	COG3833	ABC-type maltose transport systems, permease component
LZI70_18420	COG1175	transmembrane transport
LZI70_18430	COG3842	ATPase activity
LZI70_18445	COG0714	Associated with various cellular activities
LZI70_18465	COG2304	oxidoreductase activity
LZI70_18475	COG3706	GGDEF domain
LZI70_18480	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LZI70_18485	COG0581	inorganic phosphate transmembrane transporter activity
LZI70_18490	COG0573	inorganic phosphate transmembrane transporter activity
LZI70_18500	COG0840	transmembrane signaling receptor activity
LZI70_18505	COG5380	lipid catabolic process
LZI70_18510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LZI70_18515	COG0513	Belongs to the DEAD box helicase family
LZI70_18525	COG1388	LysM domain
LZI70_18525	COG1376	ErfK ybiS ycfS ynhG family protein
LZI70_18530	COG0813	purine-nucleoside phosphorylase activity
LZI70_18560	COG1566	PFAM secretion protein HlyD family protein
LZI70_18565	COG4720	Psort location CytoplasmicMembrane, score
LZI70_18570	COG1122	ATPase activity
LZI70_18590	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LZI70_18595	COG1640	4-alpha-glucanotransferase
LZI70_18600	COG0058	SHG alpha-glucan phosphorylase activity
LZI70_18620	COG1999	signal sequence binding
LZI70_18625	COG1162	GTPase activity
LZI70_18630	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LZI70_18675	COG4580	involved in the transport of maltose and maltodextrins
LZI70_18690	COG2384	SAM-dependent methyltransferase
LZI70_18695	COG0204	Acyl-transferase
LZI70_18705	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LZI70_18720	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LZI70_18725	COG4667	esterase of the alpha-beta hydrolase superfamily
LZI70_18730	COG1929	Belongs to the glycerate kinase type-1 family
LZI70_18745	COG0673	inositol 2-dehydrogenase activity
LZI70_18755	COG0583	DNA-binding transcription factor activity
LZI70_18780	COG0561	phosphatase activity
LZI70_18805	COG0798	PFAM Bile acid sodium symporter
LZI70_18810	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LZI70_18815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LZI70_18820	COG1349	DNA-binding transcription factor activity
LZI70_18825	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LZI70_18845	COG1120	ATPase activity
LZI70_18850	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LZI70_18870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LZI70_18880	COG0583	DNA-binding transcription factor activity
LZI70_18885	COG2814	Major facilitator Superfamily
LZI70_18890	COG0110	maltose O-acetyltransferase activity
LZI70_18895	COG1609	Transcriptional regulator
LZI70_18900	COG2723	6-phospho-beta-galactosidase activity
LZI70_18910	COG1410	methionine synthase
LZI70_18910	COG0646	methionine synthase
LZI70_18920	COG0604	alcohol dehydrogenase
LZI70_18920	COG1028	Short-chain dehydrogenase reductase Sdr
LZI70_18920	COG3321	synthase
LZI70_18935	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LZI70_18955	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LZI70_18965	COG1846	Transcriptional regulator
LZI70_18970	COG4175	Glycine betaine
LZI70_18990	COG1012	belongs to the aldehyde dehydrogenase family
LZI70_18995	COG1309	transcriptional regulator
LZI70_19005	COG0800	Aldolase
LZI70_19010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZI70_19015	COG4145	pantothenate transmembrane transporter activity
LZI70_19025	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LZI70_19045	COG3842	ATPase activity
LZI70_19080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LZI70_19085	COG1012	belongs to the aldehyde dehydrogenase family
LZI70_19090	COG2957	Belongs to the agmatine deiminase family
LZI70_19100	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LZI70_19105	COG1012	belongs to the aldehyde dehydrogenase family
LZI70_19110	COG1396	sequence-specific DNA binding
LZI70_19110	COG1917	Cupin 2, conserved barrel domain protein
LZI70_19115	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LZI70_19120	COG0174	glutamine synthetase
LZI70_19125	COG1757	Na H antiporter
LZI70_19140	COG1132	(ABC) transporter
LZI70_19175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZI70_19200	COG0259	pyridoxamine-phosphate oxidase activity
LZI70_19240	COG1444	tRNA N-acetyltransferase activity
LZI70_19265	COG4608	Belongs to the ABC transporter superfamily
LZI70_19270	COG0444	Belongs to the ABC transporter superfamily
LZI70_19280	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
LZI70_19280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LZI70_19300	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LZI70_19345	COG0217	transcriptional regulatory protein
LZI70_19360	COG2084	Dehydrogenase
LZI70_19375	COG1136	(ABC) transporter
LZI70_19375	COG0577	efflux transmembrane transporter activity
LZI70_19395	COG3275	phosphorelay sensor kinase activity
LZI70_19400	COG3279	Response regulator of the LytR AlgR family
LZI70_19405	COG0612	Peptidase, M16
LZI70_19425	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LZI70_19430	COG0783	Belongs to the Dps family
LZI70_19450	COG1120	ATPase activity
LZI70_19460	COG1132	(ABC) transporter
LZI70_19480	COG0346	lactoylglutathione lyase activity
LZI70_19500	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LZI70_19510	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LZI70_19525	COG4772	TonB-dependent receptor
LZI70_19530	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
LZI70_19535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LZI70_19540	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LZI70_19545	COG1120	ATPase activity
LZI70_19565	COG0395	ABC-type sugar transport system, permease component
LZI70_19570	COG1175	transmembrane transport
LZI70_19580	COG3842	ATPase activity
LZI70_19605	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LZI70_19605	COG0446	pyridine nucleotide-disulphide oxidoreductase
LZI70_19620	COG1760	l-serine dehydratase
LZI70_19655	COG0583	DNA-binding transcription factor activity
LZI70_19660	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LZI70_19665	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LZI70_19685	COG0625	glutathione transferase activity
LZI70_19690	COG0583	DNA-binding transcription factor activity
LZI70_19695	COG2249	NAD(P)H dehydrogenase (quinone) activity
LZI70_19700	COG0656	L-ascorbic acid biosynthetic process
LZI70_19705	COG0583	DNA-binding transcription factor activity
LZI70_19725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LZI70_19745	COG1917	Cupin 2, conserved barrel domain protein
LZI70_19745	COG2207	Transcriptional regulator
LZI70_19750	COG0697	spore germination
LZI70_19765	COG2233	PERMEase
LZI70_19770	COG4115	mRNA cleavage
LZI70_19775	COG2161	toxin-antitoxin pair type II binding
LZI70_19810	COG2382	esterase
LZI70_19815	COG4771	TonB-dependent receptor
LZI70_19830	COG2194	sulfuric ester hydrolase activity
LZI70_19845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LZI70_19860	COG1566	PFAM secretion protein HlyD family protein
LZI70_19875	COG0583	DNA-binding transcription factor activity
LZI70_19905	COG0628	permease
LZI70_19930	COG0668	transmembrane transport
LZI70_19935	COG1597	lipid kinase activity
LZI70_19935	COG1803	Methylglyoxal synthase
LZI70_19965	COG0583	DNA-binding transcription factor activity
LZI70_19980	COG0531	amino acid
LZI70_19990	COG0531	amino acid
LZI70_20000	COG1982	Orn Lys Arg decarboxylase major
LZI70_20005	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
LZI70_20010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LZI70_20015	COG0583	DNA-binding transcription factor activity
LZI70_20025	COG3381	protein complex oligomerization
LZI70_20040	COG0437	4 iron, 4 sulfur cluster binding
LZI70_20045	COG0243	molybdopterin cofactor binding
LZI70_20055	COG3590	peptidase
LZI70_20090	COG1733	regulation of RNA biosynthetic process
LZI70_20100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LZI70_20100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LZI70_20115	COG0415	Belongs to the DNA photolyase family
LZI70_20140	COG1192	Involved in chromosome partitioning
LZI70_20145	COG4948	Mandelate Racemase Muconate Lactonizing
LZI70_20180	COG2267	carboxylic ester hydrolase activity
LZI70_20195	COG3622	Belongs to the hyi family
LZI70_20200	COG0235	Class ii aldolase
LZI70_20205	COG3395	kinase activity
LZI70_20210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LZI70_20220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LZI70_20220	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LZI70_20225	COG1349	DNA-binding transcription factor activity
LZI70_20250	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LZI70_20260	COG0527	aspartate kinase activity
LZI70_20265	COG0662	Cupin 2, conserved barrel domain protein
LZI70_20270	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LZI70_20275	COG0456	acetyltransferase
LZI70_20280	COG4175	Glycine betaine
LZI70_20285	COG4176	ABC-type proline glycine betaine transport system permease component
LZI70_20290	COG2113	Glycine betaine
LZI70_20305	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LZI70_20310	COG0302	gtp cyclohydrolase
LZI70_20310	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LZI70_20320	COG1802	Transcriptional regulator
LZI70_20330	COG2059	Chromate
LZI70_20335	COG2059	Chromate
LZI70_20340	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LZI70_20360	COG2259	Doxx family
LZI70_20365	COG1741	Belongs to the pirin family
LZI70_20375	COG1904	glucuronate isomerase
LZI70_20380	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZI70_20385	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LZI70_20405	COG0840	transmembrane signaling receptor activity
LZI70_20425	COG1028	Short-chain dehydrogenase reductase Sdr
LZI70_20435	COG1917	Cupin 2, conserved barrel domain protein
LZI70_20445	COG0800	Aldolase
LZI70_20450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LZI70_20455	COG0450	alkyl hydroperoxide reductase
LZI70_20465	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
LZI70_20470	COG0783	Belongs to the Dps family
LZI70_20490	COG1120	ATPase activity
LZI70_20500	COG1132	(ABC) transporter