locus-tag	class	description
NVP1031O_009	COG2827	Endonuclease containing a URI domain
NVP1031O_012	COG0602	queuosine metabolic process
NVP1031O_014	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NVP1031O_016	COG0187	DNA topoisomerase II activity
NVP1031O_020	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NVP1031O_020	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NVP1031O_031	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NVP1031O_055	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NVP1031O_059	COG3475	LICD family
NVP1031O_107	COG1191	sigma factor activity
NVP1031O_113	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NVP1031O_128	COG0717	Belongs to the dCTP deaminase family
NVP1031O_130	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
