locus-tag	class	description
NVP2275O_005	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NVP2275O_038	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NVP2275O_041	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NVP2275O_044	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NVP2275O_045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NVP2275O_046	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NVP2275O_050	COG0187	DNA topoisomerase II activity
NVP2275O_063	COG2255	four-way junction helicase activity
NVP2275O_118	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NVP2275O_120	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NVP2275O_123	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NVP2275O_128	COG3409	Peptidoglycan-binding domain 1 protein
NVP2275O_128	COG3773	Cell wall hydrolase
NVP2275O_142	COG3091	SprT-like family
NVP2275O_144	COG3339	Conserved Protein
NVP2275O_199	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NVP2275O_201	COG1403	HNH endonuclease
NVP2275O_205	COG5434	Belongs to the glycosyl hydrolase 28 family
NVP2275O_216	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NVP2275O_223	COG0494	nUDIX hydrolase
NVP2275O_259	COG0740	serine-type endopeptidase activity
NVP2275O_274	COG1056	cytidyltransferase-related domain
NVP2275O_274	COG1051	belongs to the nudix hydrolase family
NVP2275O_292	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NVP2275O_301	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NVP2275O_337	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
NVP2275O_351	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NVP2275O_355	COG0459	protein refolding
NVP2275O_368	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NVP2275O_404	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NVP2275O_414	COG5434	Belongs to the glycosyl hydrolase 28 family
NVP2275O_421	COG0494	nUDIX hydrolase
NVP2275O_471	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NVP2275O_472	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NVP2275O_484	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter