locus-tag	class	description
SIPHO059v1_p0006	COG0616	signal peptide processing
SIPHO059v1_p0030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SIPHO059v1_p0030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
SIPHO059v1_p0035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
SIPHO059v1_p0039	COG0322	excinuclease ABC activity
SIPHO059v1_p0056	COG2974	May be involved in recombination