locus-tag	class	description
2018Mat004_0235	COG0328	RNA-DNA hybrid ribonuclease activity
2018Mat004_0240	COG0328	RNA-DNA hybrid ribonuclease activity
2018Mat004_0245	COG1129	ABC transporter
2018Mat004_0425	COG1518	maintenance of DNA repeat elements
2018Mat004_0540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
2018Mat004_0540	COG1328	CTP reductase activity
2018Mat004_0545	COG0602	queuosine metabolic process
2018Mat004_0725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
2018Mat004_0835	COG2974	May be involved in recombination
2018Mat004_0995	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
2018Mat004_1000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
2018Mat004_1020	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
2018Mat004_1090	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)