VCO139_0038 a6dce339499999ddca60312404d882c3 396 SUPERFAMILY SSF52540 10 395 1.0E-17 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VCO139_0038 a6dce339499999ddca60312404d882c3 396 Gene3D G3DSA:3.40.50.300 327 394 9.8E-15 T 30-10-2018 VCO139_0038 a6dce339499999ddca60312404d882c3 396 Gene3D G3DSA:3.40.50.300 1 194 1.1E-22 T 30-10-2018 VCO139_0038 a6dce339499999ddca60312404d882c3 396 Pfam PF13604 AAA domain 13 196 2.2E-10 T 30-10-2018 VCO139_0038 a6dce339499999ddca60312404d882c3 396 Pfam PF13538 UvrD-like helicase C-terminal domain 345 393 1.4E-8 T 30-10-2018 IPR027785 UvrD-like helicase C-terminal domain VCO139_0042 391ff65789ecf14713b03694ce67ac15 332 Pfam PF00476 DNA polymerase family A 63 216 1.9E-10 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VCO139_0042 391ff65789ecf14713b03694ce67ac15 332 Gene3D G3DSA:1.10.150.20 60 173 5.4E-13 T 30-10-2018 VCO139_0042 391ff65789ecf14713b03694ce67ac15 332 SUPERFAMILY SSF56672 19 237 2.56E-16 T 30-10-2018 VCO139_0050 af226f921e8a753a9d3f2b78501c3aa2 245 Pfam PF13479 AAA domain 11 170 1.9E-10 T 30-10-2018 VCO139_0050 af226f921e8a753a9d3f2b78501c3aa2 245 SUPERFAMILY SSF52540 9 154 5.93E-6 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase VCO139_0019 fb302fc40229df41dac09be50032722c 283 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 5 280 3.0E-35 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VCO139_0019 fb302fc40229df41dac09be50032722c 283 PRINTS PR00108 Thymidylate synthase family signature 52 73 5.9E-15 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VCO139_0019 fb302fc40229df41dac09be50032722c 283 PRINTS PR00108 Thymidylate synthase family signature 131 150 5.9E-15 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VCO139_0019 fb302fc40229df41dac09be50032722c 283 PRINTS PR00108 Thymidylate synthase family signature 213 230 5.9E-15 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VCO139_0019 fb302fc40229df41dac09be50032722c 283 PRINTS PR00108 Thymidylate synthase family signature 175 201 5.9E-15 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VCO139_0019 fb302fc40229df41dac09be50032722c 283 PRINTS PR00108 Thymidylate synthase family signature 157 172 5.9E-15 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VCO139_0019 fb302fc40229df41dac09be50032722c 283 Pfam PF00303 Thymidylate synthase 5 281 6.0E-64 T 30-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VCO139_0019 fb302fc40229df41dac09be50032722c 283 Gene3D G3DSA:3.30.572.10 1 282 3.5E-72 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VCO139_0019 fb302fc40229df41dac09be50032722c 283 SUPERFAMILY SSF55831 3 281 9.68E-79 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 VCO139_0041 ade7f11a2d7867e5be610db1c54e59fb 177 Gene3D G3DSA:3.90.75.20 2 114 7.5E-29 T 30-10-2018 VCO139_0041 ade7f11a2d7867e5be610db1c54e59fb 177 SUPERFAMILY SSF64496 119 175 1.07E-7 T 30-10-2018 VCO139_0041 ade7f11a2d7867e5be610db1c54e59fb 177 SMART SM00497 122 175 2.0E-4 T 30-10-2018 IPR003647 Intron encoded nuclease repeat VCO139_0041 ade7f11a2d7867e5be610db1c54e59fb 177 Pfam PF13392 HNH endonuclease 62 105 1.7E-12 T 30-10-2018 IPR003615 HNH nuclease VCO139_0041 ade7f11a2d7867e5be610db1c54e59fb 177 Gene3D G3DSA:1.10.10.10 115 177 8.6E-8 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily VCO139_0041 ade7f11a2d7867e5be610db1c54e59fb 177 SMART SM00507 57 105 2.6E-5 T 30-10-2018 IPR003615 HNH nuclease VCO139_0041 ade7f11a2d7867e5be610db1c54e59fb 177 SUPERFAMILY SSF54060 5 112 2.24E-22 T 30-10-2018 VCO139_0034 8bd0dd98822b34a2488a27bea9aeb692 128 Gene3D G3DSA:3.90.75.20 11 114 1.4E-15 T 30-10-2018 VCO139_0034 8bd0dd98822b34a2488a27bea9aeb692 128 Pfam PF13392 HNH endonuclease 61 106 1.7E-12 T 30-10-2018 IPR003615 HNH nuclease VCO139_0034 8bd0dd98822b34a2488a27bea9aeb692 128 SUPERFAMILY SSF54060 19 112 2.0E-14 T 30-10-2018 VCO139_0052 7f4e1117f2432dae0490178c5f75ab84 265 Gene3D G3DSA:3.30.1330.70 10 133 4.0E-7 T 30-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 VCO139_0052 7f4e1117f2432dae0490178c5f75ab84 265 SUPERFAMILY SSF103084 20 131 1.09E-13 T 30-10-2018 IPR036614 Holliday junction resolvase RusA-like superfamily GO:0000287|GO:0006281|GO:0006310 VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 PRINTS PR00379 Intein signature 307 319 7.8E-7 T 30-10-2018 IPR006142 Intein GO:0016539 VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 PRINTS PR00379 Intein signature 333 348 7.8E-7 T 30-10-2018 IPR006142 Intein GO:0016539 VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 PRINTS PR00379 Intein signature 214 226 7.8E-7 T 30-10-2018 IPR006142 Intein GO:0016539 VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 PRINTS PR00379 Intein signature 137 150 7.8E-7 T 30-10-2018 IPR006142 Intein GO:0016539 VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 Pfam PF17289 Terminase RNaseH-like domain 670 834 5.0E-5 T 30-10-2018 IPR035421 Terminase, large subunit gp17-like VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 SUPERFAMILY SSF55608 289 376 1.28E-16 T 30-10-2018 IPR027434 Homing endonuclease VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 Gene3D G3DSA:2.170.16.10 75 194 1.7E-6 T 30-10-2018 VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 Pfam PF14528 LAGLIDADG-like domain 308 369 3.2E-5 T 30-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 SUPERFAMILY SSF51294 83 420 5.76E-14 T 30-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 Gene3D G3DSA:3.10.28.10 198 383 5.9E-31 T 30-10-2018 IPR027434 Homing endonuclease VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 SMART SM00306 81 170 0.0073 T 30-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 VCO139_0068 02b02f8431c84e7b3ee8453f2b2b4781 870 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 400 421 0.0052 T 30-10-2018 IPR030934 Intein C-terminal splicing region VCO139_0011 0e9f9227fbc5cd30ffd62429d2df038e 408 ProSitePatterns PS00900 Bacteriophage-type RNA polymerase family active site signature 1. 72 83 - T 30-10-2018 IPR002092 DNA-directed RNA polymerase, phage-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-163282|Reactome: R-HSA-2151201 VCO139_0011 0e9f9227fbc5cd30ffd62429d2df038e 408 Gene3D G3DSA:1.10.287.280 5 63 2.2E-5 T 30-10-2018 VCO139_0011 0e9f9227fbc5cd30ffd62429d2df038e 408 SUPERFAMILY SSF56672 7 382 4.89E-37 T 30-10-2018 VCO139_0011 0e9f9227fbc5cd30ffd62429d2df038e 408 Pfam PF00940 DNA-dependent RNA polymerase 7 153 3.1E-19 T 30-10-2018 IPR002092 DNA-directed RNA polymerase, phage-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-163282|Reactome: R-HSA-2151201 VCO139_0009 0d2bb9e7e0fac4bd702ed44320870a10 313 SUPERFAMILY SSF56672 143 296 1.33E-12 T 30-10-2018 VCO139_0013 640ba5c81f72eddf18ffaab42aa32850 174 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 3 167 2.4E-32 T 30-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 VCO139_0013 640ba5c81f72eddf18ffaab42aa32850 174 SUPERFAMILY SSF53187 1 169 2.13E-40 T 30-10-2018 VCO139_0013 640ba5c81f72eddf18ffaab42aa32850 174 SMART SM00646 59 167 1.5E-20 T 30-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 VCO139_0013 640ba5c81f72eddf18ffaab42aa32850 174 Gene3D G3DSA:3.40.630.40 1 171 6.4E-45 T 30-10-2018 VCO139_0046 a74f8a2ccbf6e839c3d1e0f2552eadc4 211 SUPERFAMILY SSF54060 2 119 6.36E-28 T 30-10-2018 VCO139_0046 a74f8a2ccbf6e839c3d1e0f2552eadc4 211 Pfam PF13392 HNH endonuclease 70 115 2.9E-10 T 30-10-2018 IPR003615 HNH nuclease VCO139_0046 a74f8a2ccbf6e839c3d1e0f2552eadc4 211 Pfam PF07463 NUMOD4 motif 2 61 5.2E-13 T 30-10-2018 IPR010902 NUMOD4 GO:0016788 VCO139_0046 a74f8a2ccbf6e839c3d1e0f2552eadc4 211 Gene3D G3DSA:3.90.75.20 3 123 2.8E-36 T 30-10-2018 VCO139_0040 3370e3c1b9c836641b7d300e9663843b 559 Gene3D G3DSA:1.20.1060.10 384 496 1.5E-6 T 30-10-2018 VCO139_0040 3370e3c1b9c836641b7d300e9663843b 559 Gene3D G3DSA:3.30.420.10 135 350 1.2E-27 T 30-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 VCO139_0040 3370e3c1b9c836641b7d300e9663843b 559 Pfam PF01612 3'-5' exonuclease 136 322 5.9E-9 T 30-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 VCO139_0040 3370e3c1b9c836641b7d300e9663843b 559 SUPERFAMILY SSF56672 337 557 8.56E-29 T 30-10-2018 VCO139_0040 3370e3c1b9c836641b7d300e9663843b 559 Pfam PF00476 DNA polymerase family A 391 556 1.5E-16 T 30-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 VCO139_0040 3370e3c1b9c836641b7d300e9663843b 559 SUPERFAMILY SSF53098 139 350 9.19E-19 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily VCO139_0040 3370e3c1b9c836641b7d300e9663843b 559 Gene3D G3DSA:3.30.70.370 513 556 1.9E-10 T 30-10-2018 VCO139_0044 134941abc5b65cc3ffee2dceeb337587 149 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 7 87 9.8E-10 T 30-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 VCO139_0044 134941abc5b65cc3ffee2dceeb337587 149 SUPERFAMILY SSF101386 2 90 5.23E-7 T 30-10-2018 VCO139_0044 134941abc5b65cc3ffee2dceeb337587 149 Gene3D G3DSA:1.10.3420.10 1 148 2.7E-10 T 30-10-2018 IPR023292 NTP pyrophosphohydrolase-like domain superfamily VCO139_0032 116b6094a7a6a74a64a21208712e5e1a 191 Pfam PF07463 NUMOD4 motif 3 50 8.7E-10 T 30-10-2018 IPR010902 NUMOD4 GO:0016788 VCO139_0032 116b6094a7a6a74a64a21208712e5e1a 191 SUPERFAMILY SSF54060 3 110 1.05E-26 T 30-10-2018 VCO139_0032 116b6094a7a6a74a64a21208712e5e1a 191 Gene3D G3DSA:3.90.75.20 5 112 6.7E-33 T 30-10-2018 VCO139_0032 116b6094a7a6a74a64a21208712e5e1a 191 Pfam PF13392 HNH endonuclease 60 103 5.6E-7 T 30-10-2018 IPR003615 HNH nuclease VCO139_0036 4148671d785790bc209d4dd04635aeab 409 Pfam PF13203 Putative metallopeptidase domain 28 266 9.3E-25 T 30-10-2018 IPR025154 Putative metallopeptidase domain VCO139_0036 4148671d785790bc209d4dd04635aeab 409 Pfam PF09967 VWA-like domain (DUF2201) 283 408 6.3E-20 T 30-10-2018 IPR018698 VWA-like domain VCO139_0066 e8004162e2c968fcd0c63cdcc648f6bc 808 Pfam PF13884 Chaperone of endosialidase 712 761 1.9E-13 T 30-10-2018 IPR030392 Intramolecular chaperone auto-processing domain VCO139_0001 a99739ed1ca03e7f03a87373fc3949c9 136 Pfam PF10686 Protein of unknown function (DUF2493) 5 71 4.3E-8 T 30-10-2018 IPR019627 Mycobacteriophage D29, Gp61 VCO139_0028 29b04a473804c2fa0bf155ee6fdfeeaf 97 Pfam PF11753 Protein of unknwon function (DUF3310) 14 66 2.0E-11 T 30-10-2018 IPR021739 SaV-like VCO139_0060 5995d855916167e66cd44434e0ef9567 437 TIGRFAM TIGR04387 capsid_maj_N4: major capsid protein, N4-gp56 family 38 431 4.3E-62 T 30-10-2018 VCO139_0048 0428ff64eb39e09393744993c21658ff 640 SMART SM00942 572 638 5.7E-4 T 30-10-2018 IPR014820 Primase, C-terminal 1 VCO139_0078 466590ca6d78d02adc0567a3958f36f5 79 SUPERFAMILY SSF56496 49 77 5.1E-5 T 30-10-2018 IPR036056 Fibrinogen-like, C-terminal