locus-tag	class	description
pVa21_057	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
pVa21_061	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
pVa21_065	COG0494	nUDIX hydrolase
pVa21_128	COG0338	D12 class N6 adenine-specific DNA methyltransferase
pVa21_140	COG0328	RNA-DNA hybrid ribonuclease activity
pVa21_162	COG0653	protein targeting