phiST2_0327 1661498904f74133714e6d37270e9901 127 ProDom PD031547 REPRESSOR REGA TRANSLATION REGULATION TRANSLATIONAL RNA-BINDING EARLY GENES REGA-LIKE 3D-STRUCTURE 13 126 2.0E-62 T 30-10-2018 IPR002702 Translation repressor RegA GO:0003723 phiST2_0327 1661498904f74133714e6d37270e9901 127 SUPERFAMILY SSF55064 8 126 5.1E-56 T 30-10-2018 IPR036516 Translation repressor RegA superfamily GO:0003723 phiST2_0327 1661498904f74133714e6d37270e9901 127 Pfam PF01818 Bacteriophage translational regulator 8 126 1.0E-70 T 30-10-2018 IPR002702 Translation repressor RegA GO:0003723 phiST2_0327 1661498904f74133714e6d37270e9901 127 Gene3D G3DSA:3.30.70.650 7 127 5.2E-51 T 30-10-2018 IPR036516 Translation repressor RegA superfamily GO:0003723 phiST2_0254 80b9fc12a150b3cce89f75d8f9ff6179 366 Pfam PF00154 recA bacterial DNA recombination protein 49 276 7.6E-8 T 30-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 phiST2_0254 80b9fc12a150b3cce89f75d8f9ff6179 366 Gene3D G3DSA:3.40.50.300 27 350 4.1E-70 T 30-10-2018 phiST2_0254 80b9fc12a150b3cce89f75d8f9ff6179 366 SUPERFAMILY SSF52540 26 277 9.56E-21 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0318 562081c3a8dc80f18b5d74494f5b6176 347 Gene3D G3DSA:3.60.21.10 3 233 1.9E-19 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like phiST2_0318 562081c3a8dc80f18b5d74494f5b6176 347 SUPERFAMILY SSF56300 1 232 4.71E-25 T 30-10-2018 phiST2_0318 562081c3a8dc80f18b5d74494f5b6176 347 Pfam PF00149 Calcineurin-like phosphoesterase 3 189 2.6E-7 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 phiST2_0368 64f69e95b7573c7a007b7e4a7dc4b442 224 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 148 158 - T 30-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 phiST2_0368 64f69e95b7573c7a007b7e4a7dc4b442 224 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 38 221 31.513 T 30-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 phiST2_0368 64f69e95b7573c7a007b7e4a7dc4b442 224 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 100 116 - T 30-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 phiST2_0368 64f69e95b7573c7a007b7e4a7dc4b442 224 SUPERFAMILY SSF55620 18 221 1.56E-72 T 30-10-2018 phiST2_0368 64f69e95b7573c7a007b7e4a7dc4b442 224 Gene3D G3DSA:3.30.1130.10 89 224 1.6E-52 T 30-10-2018 phiST2_0368 64f69e95b7573c7a007b7e4a7dc4b442 224 Gene3D G3DSA:1.10.286.10 9 88 3.2E-22 T 30-10-2018 phiST2_0368 64f69e95b7573c7a007b7e4a7dc4b442 224 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 43 221 3.8E-70 T 30-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 phiST2_0368 64f69e95b7573c7a007b7e4a7dc4b442 224 Pfam PF01227 GTP cyclohydrolase I 43 220 8.9E-62 T 30-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 phiST2_0115 7c4e1136e3322ad91fab5b2acf465147 274 Gene3D G3DSA:2.40.320.10 56 216 2.6E-13 T 30-10-2018 phiST2_0115 7c4e1136e3322ad91fab5b2acf465147 274 Pfam PF01928 CYTH domain 2 194 2.7E-5 T 30-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 phiST2_0115 7c4e1136e3322ad91fab5b2acf465147 274 SUPERFAMILY SSF55154 1 214 4.58E-17 T 30-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 phiST2_0115 7c4e1136e3322ad91fab5b2acf465147 274 SMART SM01118 2 213 0.0029 T 30-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 phiST2_0032 081281df5ef0bf969ab72494bb57cc39 341 Gene3D G3DSA:3.90.79.10 200 339 1.5E-34 T 30-10-2018 phiST2_0032 081281df5ef0bf969ab72494bb57cc39 341 Pfam PF01467 Cytidylyltransferase-like 5 58 3.0E-6 T 30-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 phiST2_0032 081281df5ef0bf969ab72494bb57cc39 341 Gene3D G3DSA:3.40.50.620 1 192 8.8E-45 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold phiST2_0032 081281df5ef0bf969ab72494bb57cc39 341 Pfam PF00293 NUDIX domain 206 338 1.0E-16 T 30-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 phiST2_0032 081281df5ef0bf969ab72494bb57cc39 341 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 59 4.6E-9 T 30-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 phiST2_0032 081281df5ef0bf969ab72494bb57cc39 341 SUPERFAMILY SSF55811 200 338 3.38E-22 T 30-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 phiST2_0032 081281df5ef0bf969ab72494bb57cc39 341 SUPERFAMILY SSF52374 4 166 4.69E-18 T 30-10-2018 phiST2_0032 081281df5ef0bf969ab72494bb57cc39 341 ProSitePatterns PS00893 Nudix box signature. 233 254 - T 30-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 phiST2_0156 833e4ca3e918bb935053fd7820187e79 234 SUPERFAMILY SSF52540 18 176 1.11E-23 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0156 833e4ca3e918bb935053fd7820187e79 234 Pfam PF02562 PhoH-like protein 14 230 5.6E-66 T 30-10-2018 IPR003714 PhoH-like protein GO:0005524 phiST2_0156 833e4ca3e918bb935053fd7820187e79 234 Gene3D G3DSA:3.40.50.300 11 231 2.7E-56 T 30-10-2018 phiST2_0326 db660cacd3c3212b8fb731c0b1f8f43c 194 SUPERFAMILY SSF82771 2 87 8.63E-9 T 30-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 phiST2_0326 db660cacd3c3212b8fb731c0b1f8f43c 194 Pfam PF01541 GIY-YIG catalytic domain 3 74 1.7E-5 T 30-10-2018 IPR000305 GIY-YIG endonuclease phiST2_0326 db660cacd3c3212b8fb731c0b1f8f43c 194 SMART SM00465 2 88 9.7E-13 T 30-10-2018 IPR000305 GIY-YIG endonuclease phiST2_0326 db660cacd3c3212b8fb731c0b1f8f43c 194 SMART SM00496 142 158 180.0 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0326 db660cacd3c3212b8fb731c0b1f8f43c 194 SMART SM00496 94 110 42.0 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0326 db660cacd3c3212b8fb731c0b1f8f43c 194 SMART SM00496 111 127 1.6 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0326 db660cacd3c3212b8fb731c0b1f8f43c 194 Pfam PF07460 NUMOD3 motif (2 copies) 95 113 0.15 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0326 db660cacd3c3212b8fb731c0b1f8f43c 194 Pfam PF07460 NUMOD3 motif (2 copies) 112 155 0.0025 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0326 db660cacd3c3212b8fb731c0b1f8f43c 194 SUPERFAMILY SSF64496 116 182 5.23E-5 T 30-10-2018 phiST2_0209 fb95bf58ae5354e9849c99eb5f349f7d 340 SUPERFAMILY SSF89433 4 340 1.06E-123 T 30-10-2018 IPR036327 Bacteriophage T4, Gp8 superfamily phiST2_0209 fb95bf58ae5354e9849c99eb5f349f7d 340 Gene3D G3DSA:2.170.290.10 85 251 6.5E-169 T 30-10-2018 phiST2_0209 fb95bf58ae5354e9849c99eb5f349f7d 340 Pfam PF09215 Bacteriophage T4, Gp8 7 340 4.1E-199 T 30-10-2018 IPR015298 Bacteriophage T4, Gp8 phiST2_0209 fb95bf58ae5354e9849c99eb5f349f7d 340 Gene3D G3DSA:2.60.340.10 9 340 6.5E-169 T 30-10-2018 phiST2_0201 a8a29e6ae8e20053d169fb466e299d48 403 SUPERFAMILY SSF69349 187 386 1.33E-39 T 30-10-2018 phiST2_0201 a8a29e6ae8e20053d169fb466e299d48 403 Pfam PF06714 Gp5 N-terminal OB domain 32 148 8.5E-47 T 30-10-2018 IPR009590 Protein Gp5, N-terminal OB-fold domain GO:0005515|GO:0098025 phiST2_0201 a8a29e6ae8e20053d169fb466e299d48 403 Gene3D G3DSA:3.10.450.190 141 250 1.7E-25 T 30-10-2018 phiST2_0201 a8a29e6ae8e20053d169fb466e299d48 403 SUPERFAMILY SSF69255 4 123 3.4E-43 T 30-10-2018 phiST2_0201 a8a29e6ae8e20053d169fb466e299d48 403 Gene3D G3DSA:2.40.50.260 1 123 2.7E-42 T 30-10-2018 phiST2_0201 a8a29e6ae8e20053d169fb466e299d48 403 Pfam PF06715 Gp5 C-terminal repeat (3 copies) 289 312 3.4E-4 T 30-10-2018 IPR010609 Gp5, C-terminal phiST2_0201 a8a29e6ae8e20053d169fb466e299d48 403 Pfam PF06715 Gp5 C-terminal repeat (3 copies) 345 368 1.4E-5 T 30-10-2018 IPR010609 Gp5, C-terminal phiST2_0196 46d4a20880feefd122a7f933a3c20ace 198 ProDom PD125086 DNA GP2 END PROTECTOR TERMINAL GP2-LIKE T4 ENDS PROTECTS PROTECTING 7 179 4.0E-43 T 30-10-2018 phiST2_0308 49527a632ea62ad4f0753c044957d5d2 79 Gene3D G3DSA:3.40.30.10 1 74 3.3E-9 T 30-10-2018 phiST2_0308 49527a632ea62ad4f0753c044957d5d2 79 Pfam PF00462 Glutaredoxin 2 49 1.6E-4 T 30-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 phiST2_0308 49527a632ea62ad4f0753c044957d5d2 79 SUPERFAMILY SSF52833 2 76 2.24E-11 T 30-10-2018 IPR036249 Thioredoxin-like superfamily phiST2_0373 d29bad47d4c2b2676a0a126f937032fb 303 SUPERFAMILY SSF55620 185 272 3.41E-10 T 30-10-2018 phiST2_0373 d29bad47d4c2b2676a0a126f937032fb 303 Gene3D G3DSA:3.30.1130.10 30 148 8.0E-34 T 30-10-2018 phiST2_0373 d29bad47d4c2b2676a0a126f937032fb 303 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 33 140 2.0E-28 T 30-10-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 phiST2_0373 d29bad47d4c2b2676a0a126f937032fb 303 Pfam PF14489 QueF-like protein 204 281 1.5E-17 T 30-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 phiST2_0373 d29bad47d4c2b2676a0a126f937032fb 303 Gene3D G3DSA:3.30.1130.10 158 288 1.1E-36 T 30-10-2018 phiST2_0373 d29bad47d4c2b2676a0a126f937032fb 303 PIRSF PIRSF004750 7 293 3.1E-105 T 30-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 phiST2_0303 33b609daa30c5d181735c3b51613bf92 445 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 158 166 - T 30-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 phiST2_0303 33b609daa30c5d181735c3b51613bf92 445 SUPERFAMILY SSF56091 100 338 1.12E-36 T 30-10-2018 phiST2_0303 33b609daa30c5d181735c3b51613bf92 445 Pfam PF01068 ATP dependent DNA ligase domain 136 338 4.9E-29 T 30-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 phiST2_0303 33b609daa30c5d181735c3b51613bf92 445 SUPERFAMILY SSF50249 312 427 8.0E-24 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold phiST2_0303 33b609daa30c5d181735c3b51613bf92 445 Gene3D G3DSA:2.40.50.140 349 433 3.8E-12 T 30-10-2018 phiST2_0303 33b609daa30c5d181735c3b51613bf92 445 Pfam PF14743 DNA ligase OB-like domain 352 411 6.9E-11 T 30-10-2018 IPR029319 DNA ligase, OB-like domain phiST2_0303 33b609daa30c5d181735c3b51613bf92 445 Gene3D G3DSA:3.30.470.30 131 339 1.5E-24 T 30-10-2018 phiST2_0303 33b609daa30c5d181735c3b51613bf92 445 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 315 338 - T 30-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 phiST2_0320 a6a9764ee7b70fab241f88b7b0c971c4 745 SUPERFAMILY SSF52540 4 743 2.31E-24 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0320 a6a9764ee7b70fab241f88b7b0c971c4 745 Gene3D G3DSA:3.40.50.300 490 744 3.3E-19 T 30-10-2018 phiST2_0320 a6a9764ee7b70fab241f88b7b0c971c4 745 Gene3D G3DSA:3.40.50.300 2 258 1.9E-28 T 30-10-2018 phiST2_0320 a6a9764ee7b70fab241f88b7b0c971c4 745 SUPERFAMILY SSF75712 354 425 3.4E-5 T 30-10-2018 phiST2_0320 a6a9764ee7b70fab241f88b7b0c971c4 745 Pfam PF13555 P-loop containing region of AAA domain 22 55 3.6E-7 T 30-10-2018 phiST2_0169 9429adae473b676cbc20879698d9ddac 478 PIRSF PIRSF015417 3 126 0.0011 T 30-10-2018 IPR011205 Uncharacterised conserved protein UCP015417, vWA phiST2_0169 9429adae473b676cbc20879698d9ddac 478 PIRSF PIRSF015417 134 478 6.0E-49 T 30-10-2018 IPR011205 Uncharacterised conserved protein UCP015417, vWA phiST2_0169 9429adae473b676cbc20879698d9ddac 478 SUPERFAMILY SSF53300 266 454 1.78E-8 T 30-10-2018 IPR036465 von Willebrand factor A-like domain superfamily phiST2_0169 9429adae473b676cbc20879698d9ddac 478 Pfam PF11443 Domain of unknown function (DUF2828) 175 459 6.1E-69 T 30-10-2018 IPR024553 Domain of unknown function DUF2828 phiST2_0169 9429adae473b676cbc20879698d9ddac 478 Pfam PF11443 Domain of unknown function (DUF2828) 15 94 4.6E-9 T 30-10-2018 IPR024553 Domain of unknown function DUF2828 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 389 402 1.2E-9 T 30-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 517 529 1.2E-9 T 30-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 578 586 1.2E-9 T 30-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 SMART SM00486 101 592 1.3E-71 T 30-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 Gene3D G3DSA:1.10.287.690 456 533 3.3E-115 T 30-10-2018 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 Hamap MF_04100 DNA-directed DNA polymerase. 1 850 20.07 T 30-10-2018 IPR034749 DNA-directed DNA polymerase T4 type GO:0003677|GO:0003887|GO:0008408|GO:0039693 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 SUPERFAMILY SSF56672 359 849 8.9E-107 T 30-10-2018 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 Pfam PF00136 DNA polymerase family B 350 722 7.7E-40 T 30-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 Gene3D G3DSA:3.30.420.10 104 324 1.6E-143 T 30-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 SUPERFAMILY SSF53098 4 356 1.45E-66 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily phiST2_0330 6afe02da8e7709170453681adab43ed7 850 Pfam PF03104 DNA polymerase family B, exonuclease domain 96 274 1.3E-23 T 30-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 Gene3D G3DSA:3.90.1600.20 373 679 3.3E-115 T 30-10-2018 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 Gene3D G3DSA:3.30.342.10 4 363 1.6E-143 T 30-10-2018 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 Gene3D G3DSA:1.20.1280.300 680 832 3.2E-50 T 30-10-2018 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 ProSitePatterns PS00116 DNA polymerase family B signature. 580 588 - T 30-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 phiST2_0330 6afe02da8e7709170453681adab43ed7 850 Gene3D G3DSA:3.40.1820.10 727 815 3.2E-50 T 30-10-2018 phiST2_0167 0b857aee76b5df3399600df8a84f4bd7 511 Pfam PF03903 Phage T4 tail fibre 1 70 3.0E-9 T 30-10-2018 IPR005601 Tail fibre protein p36 phiST2_0245 8df278286801d64c19c0c1d8bd460d36 897 Gene3D G3DSA:2.60.120.260 87 259 1.1E-5 T 30-10-2018 IPR008979 Galactose-binding-like domain superfamily phiST2_0324 0100d415b185145fd386b2d2ac74b976 316 Gene3D G3DSA:1.20.272.10 227 316 1.8E-31 T 30-10-2018 phiST2_0324 0100d415b185145fd386b2d2ac74b976 316 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 48 154 9.4E-15 T 30-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 phiST2_0324 0100d415b185145fd386b2d2ac74b976 316 Gene3D G3DSA:1.10.8.60 160 226 4.7E-23 T 30-10-2018 phiST2_0324 0100d415b185145fd386b2d2ac74b976 316 SMART SM00382 41 161 3.0E-7 T 30-10-2018 IPR003593 AAA+ ATPase domain phiST2_0324 0100d415b185145fd386b2d2ac74b976 316 SUPERFAMILY SSF52540 8 214 4.91E-33 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0324 0100d415b185145fd386b2d2ac74b976 316 Gene3D G3DSA:3.40.50.300 1 157 6.0E-45 T 30-10-2018 phiST2_0256 c0cbb68381545f0496fda61f335a128b 427 SUPERFAMILY SSF52540 136 387 3.43E-24 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0256 c0cbb68381545f0496fda61f335a128b 427 Gene3D G3DSA:3.40.50.300 126 417 1.1E-39 T 30-10-2018 phiST2_0256 c0cbb68381545f0496fda61f335a128b 427 Pfam PF03796 DnaB-like helicase C terminal domain 139 391 2.3E-19 T 30-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 phiST2_0276 e7b76ed986ee1981b2aa607109750c51 299 PRINTS PR00108 Thymidylate synthase family signature 175 190 1.1E-28 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 phiST2_0276 e7b76ed986ee1981b2aa607109750c51 299 PRINTS PR00108 Thymidylate synthase family signature 193 219 1.1E-28 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 phiST2_0276 e7b76ed986ee1981b2aa607109750c51 299 PRINTS PR00108 Thymidylate synthase family signature 231 248 1.1E-28 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 phiST2_0276 e7b76ed986ee1981b2aa607109750c51 299 PRINTS PR00108 Thymidylate synthase family signature 42 63 1.1E-28 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 phiST2_0276 e7b76ed986ee1981b2aa607109750c51 299 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 298 1.0E-73 T 30-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 phiST2_0276 e7b76ed986ee1981b2aa607109750c51 299 Gene3D G3DSA:3.30.572.10 1 299 5.0E-88 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 phiST2_0276 e7b76ed986ee1981b2aa607109750c51 299 Pfam PF00303 Thymidylate synthase 2 299 4.4E-81 T 30-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 phiST2_0276 e7b76ed986ee1981b2aa607109750c51 299 SUPERFAMILY SSF55831 1 299 1.83E-80 T 30-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 phiST2_0247 3027e0e386d4f108182a5469907836df 310 Pfam PF09293 T4 RNase H, C terminal 188 310 4.2E-66 T 30-10-2018 IPR036276 T4 RNase H, C-terminal phiST2_0247 3027e0e386d4f108182a5469907836df 310 Gene3D G3DSA:3.40.50.1010 23 296 2.5E-111 T 30-10-2018 phiST2_0247 3027e0e386d4f108182a5469907836df 310 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 54 178 1.6E-13 T 30-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 phiST2_0247 3027e0e386d4f108182a5469907836df 310 SUPERFAMILY SSF88723 20 192 9.03E-35 T 30-10-2018 IPR029060 PIN-like domain superfamily phiST2_0247 3027e0e386d4f108182a5469907836df 310 SUPERFAMILY SSF47807 188 310 5.96E-43 T 30-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily phiST2_0247 3027e0e386d4f108182a5469907836df 310 Gene3D G3DSA:1.10.150.20 188 264 2.5E-111 T 30-10-2018 phiST2_0300 788b836082fba95589369932d61296db 197 Gene3D G3DSA:1.10.150.240 21 78 5.8E-5 T 30-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 phiST2_0300 788b836082fba95589369932d61296db 197 Gene3D G3DSA:3.40.50.1000 9 162 5.8E-5 T 30-10-2018 IPR023214 HAD superfamily phiST2_0300 788b836082fba95589369932d61296db 197 SUPERFAMILY SSF56784 5 187 1.21E-9 T 30-10-2018 IPR036412 HAD-like superfamily phiST2_0381 33ef2ba59d91d89dc47269af81894dd3 142 Gene3D G3DSA:3.40.1800.10 1 51 2.2E-13 T 30-10-2018 IPR038563 Recombination endonuclease VII superfamily phiST2_0381 33ef2ba59d91d89dc47269af81894dd3 142 Gene3D G3DSA:1.10.720.10 74 126 1.2E-7 T 30-10-2018 phiST2_0381 33ef2ba59d91d89dc47269af81894dd3 142 SUPERFAMILY SSF54060 1 73 4.71E-23 T 30-10-2018 phiST2_0381 33ef2ba59d91d89dc47269af81894dd3 142 Pfam PF09124 T4 recombination endonuclease VII, dimerisation 75 128 4.7E-31 T 30-10-2018 IPR015208 T4 recombination endonuclease VII, dimerisation phiST2_0381 33ef2ba59d91d89dc47269af81894dd3 142 Pfam PF02945 Recombination endonuclease VII 1 67 1.8E-14 T 30-10-2018 IPR004211 Recombination endonuclease VII phiST2_0381 33ef2ba59d91d89dc47269af81894dd3 142 SUPERFAMILY SSF68918 75 128 2.22E-18 T 30-10-2018 IPR036309 T4 recombination endonuclease VII, dimerisation domain superfamily phiST2_0338 523145baa03666ddeef6857fca1bf273 305 SUPERFAMILY SSF56784 164 305 1.9E-17 T 30-10-2018 IPR036412 HAD-like superfamily phiST2_0338 523145baa03666ddeef6857fca1bf273 305 Gene3D G3DSA:3.40.50.1000 162 305 5.5E-38 T 30-10-2018 IPR023214 HAD superfamily phiST2_0338 523145baa03666ddeef6857fca1bf273 305 Gene3D G3DSA:3.40.50.300 1 143 9.7E-33 T 30-10-2018 phiST2_0338 523145baa03666ddeef6857fca1bf273 305 Pfam PF13671 AAA domain 3 137 6.4E-18 T 30-10-2018 phiST2_0338 523145baa03666ddeef6857fca1bf273 305 SUPERFAMILY SSF52540 1 124 7.02E-16 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0241 98979b4cd566e9d1f21aac6bf90299b4 509 Pfam PF00271 Helicase conserved C-terminal domain 341 447 6.3E-7 T 30-10-2018 IPR001650 Helicase, C-terminal phiST2_0241 98979b4cd566e9d1f21aac6bf90299b4 509 Gene3D G3DSA:3.30.780.20 2 91 1.3E-26 T 30-10-2018 phiST2_0241 98979b4cd566e9d1f21aac6bf90299b4 509 SMART SM00487 111 302 9.0E-17 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain phiST2_0241 98979b4cd566e9d1f21aac6bf90299b4 509 SUPERFAMILY SSF52540 3 281 3.44E-50 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0241 98979b4cd566e9d1f21aac6bf90299b4 509 Gene3D G3DSA:3.40.50.300 92 284 1.2E-68 T 30-10-2018 phiST2_0241 98979b4cd566e9d1f21aac6bf90299b4 509 SMART SM00490 364 448 0.0064 T 30-10-2018 IPR001650 Helicase, C-terminal phiST2_0241 98979b4cd566e9d1f21aac6bf90299b4 509 Pfam PF04851 Type III restriction enzyme, res subunit 127 262 2.1E-15 T 30-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 phiST2_0241 98979b4cd566e9d1f21aac6bf90299b4 509 Gene3D G3DSA:3.40.50.300 298 509 1.2E-46 T 30-10-2018 phiST2_0241 98979b4cd566e9d1f21aac6bf90299b4 509 SUPERFAMILY SSF52540 130 500 2.95E-18 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0188 ccbc75ebb7adcf2782bc9149d0717160 151 Gene3D G3DSA:3.90.1140.10 12 148 3.0E-5 T 30-10-2018 phiST2_0188 ccbc75ebb7adcf2782bc9149d0717160 151 SUPERFAMILY SSF55144 13 126 4.71E-9 T 30-10-2018 IPR009097 Cyclic phosphodiesterase phiST2_0266 445642b3d94a88983cd4ceeed4a90de8 165 Pfam PF00692 dUTPase 26 163 4.8E-26 T 30-10-2018 IPR029054 dUTPase-like phiST2_0266 445642b3d94a88983cd4ceeed4a90de8 165 TIGRFAM TIGR00576 dut: dUTP diphosphatase 27 163 7.0E-35 T 30-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 phiST2_0266 445642b3d94a88983cd4ceeed4a90de8 165 SUPERFAMILY SSF51283 27 164 2.62E-35 T 30-10-2018 IPR036157 dUTPase-like superfamily phiST2_0266 445642b3d94a88983cd4ceeed4a90de8 165 Gene3D G3DSA:2.70.40.10 12 164 2.7E-43 T 30-10-2018 IPR036157 dUTPase-like superfamily phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 Pfam PF03477 ATP cone domain 1 86 3.5E-13 T 30-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 SUPERFAMILY SSF51998 216 729 6.1E-144 T 30-10-2018 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 140 724 1.2E-148 T 30-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 SUPERFAMILY SSF48168 7 215 9.16E-64 T 30-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 Pfam PF02867 Ribonucleotide reductase, barrel domain 217 720 4.7E-108 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 586 608 - T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 Gene3D G3DSA:3.20.70.20 73 729 7.5E-145 T 30-10-2018 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 PRINTS PR01183 Ribonucleotide reductase large chain signature 425 436 4.1E-28 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 PRINTS PR01183 Ribonucleotide reductase large chain signature 526 549 4.1E-28 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 PRINTS PR01183 Ribonucleotide reductase large chain signature 292 311 4.1E-28 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 PRINTS PR01183 Ribonucleotide reductase large chain signature 462 485 4.1E-28 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 PRINTS PR01183 Ribonucleotide reductase large chain signature 597 624 4.1E-28 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 PRINTS PR01183 Ribonucleotide reductase large chain signature 499 521 4.1E-28 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0141 802a1c79bbc12deeebf5e4ae4a2cc6a9 741 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 137 213 2.4E-14 T 30-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 SUPERFAMILY SSF55874 5 226 3.01E-40 T 30-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 47 188 6.5E-11 T 30-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 SMART SM00387 48 190 2.6E-4 T 30-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 SMART SM00433 48 597 5.6E-28 T 30-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 PRINTS PR00418 DNA topoisomerase II family signature 405 419 2.5E-31 T 30-10-2018 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 PRINTS PR00418 DNA topoisomerase II family signature 546 562 2.5E-31 T 30-10-2018 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 PRINTS PR00418 DNA topoisomerase II family signature 48 63 2.5E-31 T 30-10-2018 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 PRINTS PR00418 DNA topoisomerase II family signature 470 486 2.5E-31 T 30-10-2018 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 PRINTS PR00418 DNA topoisomerase II family signature 129 143 2.5E-31 T 30-10-2018 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 PRINTS PR00418 DNA topoisomerase II family signature 85 98 2.5E-31 T 30-10-2018 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 PRINTS PR00418 DNA topoisomerase II family signature 263 276 2.5E-31 T 30-10-2018 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 Gene3D G3DSA:3.30.230.10 242 368 1.9E-22 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 Pfam PF00204 DNA gyrase B 249 383 1.7E-19 T 30-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 SUPERFAMILY SSF54211 231 383 3.79E-26 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 Gene3D G3DSA:3.40.50.670 378 597 9.4E-45 T 30-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 SUPERFAMILY SSF56719 391 597 8.11E-44 T 30-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 Pfam PF16898 C-terminal associated domain of TOPRIM 515 597 2.7E-9 T 30-10-2018 IPR031660 C-terminal associated domain of TOPRIM Reactome: R-HSA-4615885 phiST2_0289 2e677ff007a67bad90e0c32101d72699 597 Gene3D G3DSA:3.30.565.10 10 241 3.8E-52 T 30-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily phiST2_0222 58ae6a1cb44d2026edc44e46b7b2a0fd 671 Pfam PF17482 Phage tail sheath C-terminal domain 560 659 2.1E-21 T 30-10-2018 IPR020287 Tail sheath protein, C-terminal domain phiST2_0222 58ae6a1cb44d2026edc44e46b7b2a0fd 671 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 358 556 2.7E-47 T 30-10-2018 IPR035089 Tail sheath protein, subtilisin-like domain phiST2_0222 58ae6a1cb44d2026edc44e46b7b2a0fd 671 Gene3D G3DSA:3.40.50.11780 22 130 4.0E-23 T 30-10-2018 phiST2_0222 58ae6a1cb44d2026edc44e46b7b2a0fd 671 Gene3D G3DSA:3.40.50.11780 349 524 6.3E-46 T 30-10-2018 phiST2_0222 58ae6a1cb44d2026edc44e46b7b2a0fd 671 Pfam PF17481 Phage tail sheath protein beta-sandwich domain 166 357 7.0E-26 T 30-10-2018 IPR035326 Phage tail sheath protein, beta-sandwich domain phiST2_0255 b9411d38eff8638d3e7781fdd9761da3 100 Pfam PF11113 Head assembly gene product 28 64 6.7E-7 T 30-10-2018 IPR021049 Bacteriophage T4, Gp40, head assembly phiST2_0243 9c459d38f8f85747d56c32ec35a46c44 137 SUPERFAMILY SSF89095 2 133 7.32E-19 T 30-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 phiST2_0243 9c459d38f8f85747d56c32ec35a46c44 137 Gene3D G3DSA:1.10.10.410 81 134 8.0E-9 T 30-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal phiST2_0243 9c459d38f8f85747d56c32ec35a46c44 137 Pfam PF09424 Yqey-like protein 11 132 7.2E-15 T 30-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 SUPERFAMILY SSF64496 140 226 1.07E-15 T 30-10-2018 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 TIGRFAM TIGR01453 grpIintron_endo: group I intron endonuclease 2 136 1.1E-19 T 30-10-2018 IPR006350 Intron endonuclease, group I GO:0004519 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 SMART SM00465 1 87 1.6E-9 T 30-10-2018 IPR000305 GIY-YIG endonuclease phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 SUPERFAMILY SSF64496 94 137 1.12E-7 T 30-10-2018 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 Pfam PF07460 NUMOD3 motif (2 copies) 93 129 1.0E-11 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 Pfam PF07460 NUMOD3 motif (2 copies) 140 173 1.9E-13 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 Pfam PF07460 NUMOD3 motif (2 copies) 117 136 0.018 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 Pfam PF01541 GIY-YIG catalytic domain 2 36 4.6E-7 T 30-10-2018 IPR000305 GIY-YIG endonuclease phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 SUPERFAMILY SSF82771 2 86 1.57E-11 T 30-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 Gene3D G3DSA:3.40.1440.10 2 88 1.4E-7 T 30-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 SMART SM00496 160 176 0.015 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 SMART SM00496 136 152 9.9 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 SMART SM00496 116 132 1.3 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0012 153d28c3f0a3c77e9ef79bbff4053398 231 SMART SM00496 92 108 0.0023 T 30-10-2018 IPR003611 Nuclease associated modular domain 3 GO:0003677 phiST2_0168 148a839a5b69418d40395a2903f808e9 174 Pfam PF04308 Ribonuclease H-like 7 143 9.8E-17 T 30-10-2018 IPR007405 Bacteriophage KVP40, Orf299 phiST2_0065 bfc23fd1aa29f099c96b528aa73970a9 189 Gene3D G3DSA:3.40.50.300 1 139 1.3E-22 T 30-10-2018 phiST2_0065 bfc23fd1aa29f099c96b528aa73970a9 189 SUPERFAMILY SSF52540 1 139 3.42E-32 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0065 bfc23fd1aa29f099c96b528aa73970a9 189 PIRSF PIRSF035805 1 189 4.6E-52 T 30-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 phiST2_0065 bfc23fd1aa29f099c96b528aa73970a9 189 Pfam PF00265 Thymidine kinase 3 185 1.5E-36 T 30-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 phiST2_0065 bfc23fd1aa29f099c96b528aa73970a9 189 Hamap MF_00124 Thymidine kinase [tdk]. 1 188 27.743 T 30-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 phiST2_0065 bfc23fd1aa29f099c96b528aa73970a9 189 SUPERFAMILY SSF57716 142 187 2.47E-5 T 30-10-2018 phiST2_0148 ba4506e19c99ef0e82d3bb68dbc63e29 294 Gene3D G3DSA:3.20.20.70 4 247 2.3E-23 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 phiST2_0148 ba4506e19c99ef0e82d3bb68dbc63e29 294 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 291 27.508 T 30-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 phiST2_0148 ba4506e19c99ef0e82d3bb68dbc63e29 294 SUPERFAMILY SSF102114 96 157 2.16E-7 T 30-10-2018 phiST2_0148 ba4506e19c99ef0e82d3bb68dbc63e29 294 Pfam PF13394 4Fe-4S single cluster domain 24 160 3.8E-12 T 30-10-2018 phiST2_0025 c25337816f6e1f219853f70539be5868 89 Pfam PF10686 Protein of unknown function (DUF2493) 1 38 8.2E-10 T 30-10-2018 IPR019627 Mycobacteriophage D29, Gp61 phiST2_0220 4af063c5c4ab90c72b5314275a269d0a 182 Pfam PF11053 Terminase DNA packaging enzyme 7 155 1.1E-81 T 30-10-2018 IPR020342 Bacteriophage T4, Gp16, DNA-packaging phiST2_0220 4af063c5c4ab90c72b5314275a269d0a 182 ProDom PD096257 TERMINASE SUBUNIT DNA SMALL PACKAGING ENZYME GP16 GP16V DNA-BINDING GP16-LIKE 6 151 2.0E-81 T 30-10-2018 IPR020342 Bacteriophage T4, Gp16, DNA-packaging phiST2_0220 4af063c5c4ab90c72b5314275a269d0a 182 Gene3D G3DSA:1.10.287.1060 46 123 6.5E-33 T 30-10-2018 phiST2_0257 d3934c3d4ecfb5a1ee441220afbde351 611 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 17 610 2.4E-176 T 30-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 phiST2_0257 d3934c3d4ecfb5a1ee441220afbde351 611 SUPERFAMILY SSF51998 22 591 8.24E-188 T 30-10-2018 phiST2_0257 d3934c3d4ecfb5a1ee441220afbde351 611 ProSitePatterns PS00850 Glycine radical domain signature. 581 589 - T 30-10-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site phiST2_0257 d3934c3d4ecfb5a1ee441220afbde351 611 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 16 610 2.4E-186 T 30-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 phiST2_0257 d3934c3d4ecfb5a1ee441220afbde351 611 Gene3D G3DSA:3.20.70.20 22 592 3.1E-220 T 30-10-2018 phiST2_0230 f0f72b5c791c4550c4d31f50952f23cb 365 Gene3D G3DSA:3.30.460.10 1 143 1.6E-23 T 30-10-2018 phiST2_0230 f0f72b5c791c4550c4d31f50952f23cb 365 Gene3D G3DSA:1.10.3090.10 144 362 2.4E-24 T 30-10-2018 phiST2_0230 f0f72b5c791c4550c4d31f50952f23cb 365 SUPERFAMILY SSF81891 142 356 2.62E-26 T 30-10-2018 phiST2_0230 f0f72b5c791c4550c4d31f50952f23cb 365 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 171 221 2.0E-6 T 30-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 phiST2_0230 f0f72b5c791c4550c4d31f50952f23cb 365 SUPERFAMILY SSF81301 8 141 8.07E-21 T 30-10-2018 phiST2_0230 f0f72b5c791c4550c4d31f50952f23cb 365 Pfam PF01743 Poly A polymerase head domain 11 144 6.8E-16 T 30-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 phiST2_0191 73963d19bd2733b7fcc24566750a8b57 178 Pfam PF06841 T4-like virus tail tube protein gp19 8 160 1.4E-11 T 30-10-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 phiST2_0340 18b994e749c872355a640f3bbc24f8b6 170 SUPERFAMILY SSF52949 3 163 6.56E-29 T 30-10-2018 phiST2_0340 18b994e749c872355a640f3bbc24f8b6 170 SMART SM00506 2 148 0.0059 T 30-10-2018 IPR002589 Macro domain phiST2_0340 18b994e749c872355a640f3bbc24f8b6 170 Gene3D G3DSA:3.40.220.10 3 169 1.7E-24 T 30-10-2018 phiST2_0340 18b994e749c872355a640f3bbc24f8b6 170 Pfam PF01661 Macro domain 32 147 2.3E-5 T 30-10-2018 IPR002589 Macro domain phiST2_0145 c6486bff750a879fa607f292921231e0 334 SMART SM00382 106 254 0.0018 T 30-10-2018 IPR003593 AAA+ ATPase domain phiST2_0145 c6486bff750a879fa607f292921231e0 334 SUPERFAMILY SSF52540 87 304 4.11E-12 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0323 81d2503fc2a93392219929e47c62043e 221 SUPERFAMILY SSF55979 114 220 2.98E-28 T 30-10-2018 phiST2_0323 81d2503fc2a93392219929e47c62043e 221 Pfam PF09116 gp45 sliding clamp, C terminal 117 220 5.8E-38 T 30-10-2018 IPR015200 Gp45 sliding clamp, C-terminal GO:0039693 phiST2_0323 81d2503fc2a93392219929e47c62043e 221 SUPERFAMILY SSF55979 1 109 1.81E-34 T 30-10-2018 phiST2_0323 81d2503fc2a93392219929e47c62043e 221 Gene3D G3DSA:3.70.10.10 1 221 5.4E-73 T 30-10-2018 phiST2_0376 027ee592eb4fdacd4b0d699e15e98593 91 Pfam PF10902 WYL_2, Sm-like SH3 beta-barrel fold 6 84 4.5E-23 T 30-10-2018 IPR024401 WYL domain containing protein phiST2_0376 027ee592eb4fdacd4b0d699e15e98593 91 ProDom PD068623 ORF GP31.1 GP31-CD B 6 90 3.0E-4 T 30-10-2018 phiST2_0142 2d4435c689a48e483f2dde28956daf42 374 Gene3D G3DSA:1.10.620.20 2 338 1.3E-125 T 30-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 phiST2_0142 2d4435c689a48e483f2dde28956daf42 374 ProSitePatterns PS00368 Ribonucleotide reductase small subunit signature. 115 131 - T 30-10-2018 IPR030475 Ribonucleotide reductase small subunit, acitve site KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0142 2d4435c689a48e483f2dde28956daf42 374 SUPERFAMILY SSF47240 3 339 3.98E-95 T 30-10-2018 IPR009078 Ferritin-like superfamily phiST2_0142 2d4435c689a48e483f2dde28956daf42 374 Pfam PF00268 Ribonucleotide reductase, small chain 31 328 2.1E-41 T 30-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 phiST2_0094 c5e613820e8e59e63fe7123241020dee 224 Pfam PF04973 Nicotinamide mononucleotide transporter 23 212 3.3E-45 T 30-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 phiST2_0094 c5e613820e8e59e63fe7123241020dee 224 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 23 213 3.4E-31 T 30-10-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 phiST2_0244 00160f1e50ef14bbc1f486e42b1909b5 137 Pfam PF11056 Recombination, repair and ssDNA binding protein UvsY 9 135 2.2E-47 T 30-10-2018 IPR021289 Recombination, repair and ssDNA binding protein UvsY phiST2_0221 57f2e85a8dbaf3ee0ea95df0c9758c94 600 Gene3D G3DSA:3.30.420.240 340 557 2.2E-76 T 30-10-2018 phiST2_0221 57f2e85a8dbaf3ee0ea95df0c9758c94 600 Pfam PF17289 Terminase RNaseH-like domain 384 555 3.2E-48 T 30-10-2018 IPR035421 Terminase, large subunit gp17-like phiST2_0221 57f2e85a8dbaf3ee0ea95df0c9758c94 600 Gene3D G3DSA:3.40.50.300 44 299 1.6E-76 T 30-10-2018 phiST2_0221 57f2e85a8dbaf3ee0ea95df0c9758c94 600 SUPERFAMILY SSF52540 120 290 1.2E-8 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0221 57f2e85a8dbaf3ee0ea95df0c9758c94 600 Pfam PF03237 Terminase-like family 143 355 6.2E-40 T 30-10-2018 IPR004921 Terminase large subunit, T4likevirus-type phiST2_0163 dbff8d4b0ece75160dd86a574d490ce7 191 Gene3D G3DSA:1.20.5.170 126 191 1.5E-5 T 30-10-2018 phiST2_0164 01986cba435063dd90360f5306b779cf 1337 Pfam PF13884 Chaperone of endosialidase 1229 1283 5.8E-15 T 30-10-2018 IPR030392 Intramolecular chaperone auto-processing domain phiST2_0212 bbf67e6e846ea695b4d0aa517f2df0fa 228 SUPERFAMILY SSF56558 16 228 3.66E-46 T 30-10-2018 IPR036214 Baseplate structural protein Gp11 superfamily phiST2_0212 bbf67e6e846ea695b4d0aa517f2df0fa 228 Pfam PF08677 GP11 baseplate wedge protein 2 228 5.3E-116 T 30-10-2018 IPR014791 Baseplate structural protein Gp11 phiST2_0212 bbf67e6e846ea695b4d0aa517f2df0fa 228 Gene3D G3DSA:3.90.1160.10 90 203 1.5E-6 T 30-10-2018 IPR015976 Bacteriophage T4, Gp11, C-terminal phiST2_0212 bbf67e6e846ea695b4d0aa517f2df0fa 228 Gene3D G3DSA:2.20.20.20 76 226 1.5E-6 T 30-10-2018 phiST2_0273 02038bc66873fcd2bffbbadd35030e30 147 SUPERFAMILY SSF102462 19 70 5.58E-5 T 30-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 phiST2_0273 02038bc66873fcd2bffbbadd35030e30 147 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 19 72 7.0E-5 T 30-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 phiST2_0273 02038bc66873fcd2bffbbadd35030e30 147 Gene3D G3DSA:3.40.1490.10 11 106 1.7E-6 T 30-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 phiST2_0315 b59d2409751ecd4b558145c6a93eb165 116 Pfam PF10849 Protein of unknown function (DUF2654) 37 105 1.3E-38 T 30-10-2018 IPR022558 Protein of unknown function DUF2654 phiST2_0315 b59d2409751ecd4b558145c6a93eb165 116 ProDom PD069849 A-GT.4 ORF A T4 MOBB-GP55 A-GT.4-LIKE 29 105 3.0E-34 T 30-10-2018 IPR022558 Protein of unknown function DUF2654 phiST2_0223 e0d47ac84a877a6041d4027006d7b26d 166 Pfam PF06841 T4-like virus tail tube protein gp19 21 164 4.7E-10 T 30-10-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 phiST2_0223 e0d47ac84a877a6041d4027006d7b26d 166 ProDom PD034665 TAIL TUBE GP19 MONOMER STRUCTURAL GP19-LIKE GP19V GP54 SEQUENCING DIRECT 7 163 7.0E-88 T 30-10-2018 phiST2_0268 3b0b8de33f023cd31dffcb3925e9cb64 230 SUPERFAMILY SSF53098 5 201 7.48E-8 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily phiST2_0268 3b0b8de33f023cd31dffcb3925e9cb64 230 Pfam PF16473 3' exoribonuclease, RNase T-like 9 192 1.7E-17 T 30-10-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain phiST2_0295 fe164976af13b87becb44c1a186b8867 242 SUPERFAMILY SSF56300 3 231 1.19E-20 T 30-10-2018 phiST2_0295 fe164976af13b87becb44c1a186b8867 242 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 5 225 1.2E-7 T 30-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 phiST2_0295 fe164976af13b87becb44c1a186b8867 242 Gene3D G3DSA:3.60.21.10 2 242 1.4E-14 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like phiST2_0251 59e45e01a50361933eaacd8c3e4806d8 308 Gene3D G3DSA:3.90.198.10 22 252 1.3E-88 T 30-10-2018 phiST2_0251 59e45e01a50361933eaacd8c3e4806d8 308 Pfam PF08804 gp32 DNA binding protein like 28 116 3.2E-49 T 30-10-2018 IPR012339 Bacteriophage T4, Gp32, single-stranded DNA-binding GO:0003697 phiST2_0251 59e45e01a50361933eaacd8c3e4806d8 308 SUPERFAMILY SSF50249 24 237 8.57E-94 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold phiST2_0203 a6aa0c27ee823ddd3ccf2b18141d5297 98 Pfam PF05488 PAAR motif 12 89 3.2E-11 T 30-10-2018 IPR008727 PAAR motif phiST2_0203 a6aa0c27ee823ddd3ccf2b18141d5297 98 Gene3D G3DSA:2.60.200.60 4 97 1.4E-26 T 30-10-2018 phiST2_0146 f2398826a16cfb61279aedc5ef9cb085 428 SMART SM00434 3 423 1.2E-73 T 30-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 phiST2_0146 f2398826a16cfb61279aedc5ef9cb085 428 Gene3D G3DSA:3.90.199.10 29 427 3.8E-92 T 30-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 phiST2_0146 f2398826a16cfb61279aedc5ef9cb085 428 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 24 425 3.6E-78 T 30-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 phiST2_0146 f2398826a16cfb61279aedc5ef9cb085 428 Gene3D G3DSA:1.10.268.10 326 413 3.8E-92 T 30-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 phiST2_0146 f2398826a16cfb61279aedc5ef9cb085 428 SUPERFAMILY SSF56719 3 427 1.7E-93 T 30-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 phiST2_0146 f2398826a16cfb61279aedc5ef9cb085 428 Gene3D G3DSA:3.30.1360.40 198 290 3.8E-92 T 30-10-2018 phiST2_0194 27fa7f75bc714af93533a83da9871175 282 Pfam PF12322 T4 bacteriophage base plate protein 15 105 3.1E-12 T 30-10-2018 IPR024364 Baseplate hub assembly protein, bacteriophage T4-like phiST2_0194 27fa7f75bc714af93533a83da9871175 282 Pfam PF12322 T4 bacteriophage base plate protein 121 281 2.3E-17 T 30-10-2018 IPR024364 Baseplate hub assembly protein, bacteriophage T4-like phiST2_0250 549eacbe00b02ff66e6cd2e803df8983 186 Pfam PF08993 T4 gene Gp59 loader of gp41 DNA helicase 1 77 2.3E-40 T 30-10-2018 IPR015085 Bacteriophage T4, Gp59, helicase assembly protein, N-terminal phiST2_0250 549eacbe00b02ff66e6cd2e803df8983 186 Gene3D G3DSA:1.10.220.50 78 185 2.0E-29 T 30-10-2018 IPR037082 Bacteriophage T4, Gp59, helicase assembly protein, C-terminal domain superfamily phiST2_0250 549eacbe00b02ff66e6cd2e803df8983 186 Gene3D G3DSA:1.10.8.60 1 77 2.1E-22 T 30-10-2018 phiST2_0250 549eacbe00b02ff66e6cd2e803df8983 186 SUPERFAMILY SSF48493 1 184 9.02E-66 T 30-10-2018 IPR023197 Bacteriophage T4, Gp59, helicase assembly protein domain superfamily phiST2_0250 549eacbe00b02ff66e6cd2e803df8983 186 Pfam PF08994 T4 gene Gp59 loader of gp41 DNA helicase C-term 84 184 3.5E-41 T 30-10-2018 IPR015086 Bacteriophage T4, Gp59, helicase assembly protein, C-terminal phiST2_0190 b1762d13dd7291b15435ce96cfedf9b8 214 Gene3D G3DSA:1.10.238.70 34 128 4.7E-38 T 30-10-2018 IPR023191 Deoxynucleotide monophosphate kinase, N-terminal MetaCyc: PWY-7197 phiST2_0190 b1762d13dd7291b15435ce96cfedf9b8 214 SUPERFAMILY SSF52540 1 211 6.31E-12 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0190 b1762d13dd7291b15435ce96cfedf9b8 214 Gene3D G3DSA:3.40.50.300 2 210 4.7E-38 T 30-10-2018 phiST2_0166 c92bac3682f4c262c3b33555b561311c 1152 SUPERFAMILY SSF49899 2 213 4.69E-20 T 30-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily phiST2_0166 c92bac3682f4c262c3b33555b561311c 1152 Gene3D G3DSA:2.60.120.200 970 1151 9.7E-8 T 30-10-2018 phiST2_0166 c92bac3682f4c262c3b33555b561311c 1152 Gene3D G3DSA:2.60.120.200 538 726 1.9E-17 T 30-10-2018 phiST2_0166 c92bac3682f4c262c3b33555b561311c 1152 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 548 692 1.1E-13 T 30-10-2018 phiST2_0166 c92bac3682f4c262c3b33555b561311c 1152 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 978 1125 4.8E-9 T 30-10-2018 phiST2_0166 c92bac3682f4c262c3b33555b561311c 1152 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 50 209 9.5E-15 T 30-10-2018 phiST2_0166 c92bac3682f4c262c3b33555b561311c 1152 SUPERFAMILY SSF49899 511 697 4.25E-17 T 30-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily phiST2_0166 c92bac3682f4c262c3b33555b561311c 1152 Gene3D G3DSA:2.60.120.200 9 217 1.1E-20 T 30-10-2018 phiST2_0166 c92bac3682f4c262c3b33555b561311c 1152 SUPERFAMILY SSF49899 920 1125 4.66E-7 T 30-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily phiST2_0309 c4f985e2673d7e2b6b5149180dfc184f 299 Gene3D G3DSA:3.30.2320.40 115 223 5.5E-9 T 30-10-2018 phiST2_0309 c4f985e2673d7e2b6b5149180dfc184f 299 Pfam PF07068 Major capsid protein Gp23 158 273 6.1E-5 T 30-10-2018 IPR010762 Capsid protein, T4-like bacteriophage-like GO:0019012|GO:0019028 phiST2_0309 c4f985e2673d7e2b6b5149180dfc184f 299 Pfam PF07068 Major capsid protein Gp23 54 129 3.4E-4 T 30-10-2018 IPR010762 Capsid protein, T4-like bacteriophage-like GO:0019012|GO:0019028 phiST2_0132 315ccb27dddabde3af0037eae3ade974 497 Pfam PF04095 Nicotinate phosphoribosyltransferase (NAPRTase) family 177 424 2.8E-52 T 30-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 phiST2_0132 315ccb27dddabde3af0037eae3ade974 497 Gene3D G3DSA:3.20.20.70 140 398 2.9E-91 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 phiST2_0132 315ccb27dddabde3af0037eae3ade974 497 SUPERFAMILY SSF51690 143 483 1.59E-39 T 30-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 phiST2_0132 315ccb27dddabde3af0037eae3ade974 497 PIRSF PIRSF005943 1 486 9.2E-190 T 30-10-2018 IPR016471 Nicotinamide phosphoribosyl transferase Reactome: R-HSA-1368108|Reactome: R-HSA-197264 phiST2_0026 497a85b2b39ccfbc726bb62d3a20472a 421 Pfam PF13604 AAA domain 3 186 6.0E-33 T 30-10-2018 phiST2_0026 497a85b2b39ccfbc726bb62d3a20472a 421 SUPERFAMILY SSF52540 2 417 4.87E-32 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0026 497a85b2b39ccfbc726bb62d3a20472a 421 Gene3D G3DSA:2.30.30.780 249 371 1.0E-81 T 30-10-2018 phiST2_0026 497a85b2b39ccfbc726bb62d3a20472a 421 Gene3D G3DSA:3.40.50.300 173 420 1.0E-81 T 30-10-2018 phiST2_0026 497a85b2b39ccfbc726bb62d3a20472a 421 Gene3D G3DSA:3.40.50.300 2 167 1.6E-38 T 30-10-2018 phiST2_0211 30d05338a7510ad67e500bc5fd28bc99 748 SUPERFAMILY SSF50017 1 285 2.62E-63 T 30-10-2018 IPR036240 Gp9-like superfamily GO:0019076|GO:0098025 phiST2_0211 30d05338a7510ad67e500bc5fd28bc99 748 Gene3D G3DSA:1.20.5.960 12 46 1.4E-6 T 30-10-2018 phiST2_0211 30d05338a7510ad67e500bc5fd28bc99 748 Pfam PF07880 Bacteriophage T4 gp9/10-like protein 2 186 7.6E-25 T 30-10-2018 IPR008987 Baseplate structural protein Gp9/Gp10 GO:0019076|GO:0098025 phiST2_0195 7cb3067281b177f80498d46571651682 248 ProDom PD034665 TAIL TUBE GP19 MONOMER STRUCTURAL GP19-LIKE GP19V GP54 SEQUENCING DIRECT 78 206 4.0E-62 T 30-10-2018 phiST2_0195 7cb3067281b177f80498d46571651682 248 Pfam PF06841 T4-like virus tail tube protein gp19 103 207 1.4E-6 T 30-10-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 phiST2_0367 81c05013caeb1ec94e47aee9853ab23c 310 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 172 299 3.2E-6 T 30-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 phiST2_0367 81c05013caeb1ec94e47aee9853ab23c 310 Gene3D G3DSA:3.30.479.10 12 165 7.8E-11 T 30-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 phiST2_0367 81c05013caeb1ec94e47aee9853ab23c 310 SUPERFAMILY SSF55620 171 299 8.34E-15 T 30-10-2018 phiST2_0367 81c05013caeb1ec94e47aee9853ab23c 310 SUPERFAMILY SSF55620 3 162 2.08E-10 T 30-10-2018 phiST2_0214 15831f37a3922028f0787712f5461cd7 475 SUPERFAMILY SSF88874 338 473 2.28E-9 T 30-10-2018 phiST2_0009 2e7808a2e905606e205b89c8e4b43327 689 Gene3D G3DSA:3.30.565.10 4 208 3.3E-17 T 30-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily phiST2_0009 2e7808a2e905606e205b89c8e4b43327 689 SUPERFAMILY SSF55874 30 183 3.21E-14 T 30-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily phiST2_0046 2f0be2608cc0157c640a2db08abe9685 249 SUPERFAMILY SSF82771 59 137 6.02E-7 T 30-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 phiST2_0144 c4c22657261028cc111a9ca1109e0d28 190 SUPERFAMILY SSF53955 50 180 1.16E-12 T 30-10-2018 IPR023346 Lysozyme-like domain superfamily phiST2_0144 c4c22657261028cc111a9ca1109e0d28 190 Gene3D G3DSA:1.10.530.10 49 187 2.6E-10 T 30-10-2018 phiST2_0144 c4c22657261028cc111a9ca1109e0d28 190 Pfam PF01464 Transglycosylase SLT domain 55 170 1.3E-9 T 30-10-2018 IPR008258 Transglycosylase SLT domain 1 phiST2_0260 27bfaf2f7998af50a1dcba147e254f84 158 PIRSF PIRSF000368 1 157 9.1E-56 T 30-10-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 phiST2_0260 27bfaf2f7998af50a1dcba147e254f84 158 ProSitePatterns PS01087 Radical activating enzymes signature. 14 35 - T 30-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 phiST2_0260 27bfaf2f7998af50a1dcba147e254f84 158 Gene3D G3DSA:3.20.20.70 2 153 6.9E-21 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 phiST2_0260 27bfaf2f7998af50a1dcba147e254f84 158 SUPERFAMILY SSF102114 22 97 1.57E-8 T 30-10-2018 phiST2_0260 27bfaf2f7998af50a1dcba147e254f84 158 Pfam PF13353 4Fe-4S single cluster domain 12 143 4.4E-42 T 30-10-2018 phiST2_0260 27bfaf2f7998af50a1dcba147e254f84 158 TIGRFAM TIGR02491 NrdG: anaerobic ribonucleoside-triphosphate reductase activating protein 2 144 8.6E-53 T 30-10-2018 IPR012837 Ribonucleoside-triphosphate reductase activating, anaerobic GO:0005737|GO:0043365|GO:0051539|GO:0055114 phiST2_0253 906d21e553ea6c6dcfc6995a4a74ac81 238 Gene3D G3DSA:3.90.226.10 16 172 9.7E-24 T 30-10-2018 phiST2_0253 906d21e553ea6c6dcfc6995a4a74ac81 238 SUPERFAMILY SSF52096 20 167 1.7E-23 T 30-10-2018 IPR029045 ClpP/crotonase-like domain superfamily phiST2_0253 906d21e553ea6c6dcfc6995a4a74ac81 238 Pfam PF00574 Clp protease 34 167 6.7E-13 T 30-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA phiST2_0249 d32317d01c7b5eb3aaf830ba404ad25a 100 Gene3D G3DSA:1.10.10.2850 23 95 9.1E-8 T 30-10-2018 phiST2_0249 d32317d01c7b5eb3aaf830ba404ad25a 100 Pfam PF16805 Phage late-transcription coactivator 27 96 1.3E-22 T 30-10-2018 IPR031836 Phage late-transcription coactivator phiST2_0248 b47473e9bf773de205ff1e01aa2e2d55 93 ProDom PD062891 DSBA BINDING DSDNA A DNA DOUBLE-STRANDED T4 DNA-BINDING LATE TRANSCRIPTION 21 87 3.0E-31 T 30-10-2018 IPR020313 Double-stranded DNA-binding protein phiST2_0248 b47473e9bf773de205ff1e01aa2e2d55 93 Pfam PF11126 Transcriptional regulator DsbA 22 88 3.6E-39 T 30-10-2018 IPR020313 Double-stranded DNA-binding protein phiST2_0275 a6eb24afbe15eac0a09292f002e82be4 67 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 26 1.1E-6 T 30-10-2018 IPR012902 Prokaryotic N-terminal methylation site phiST2_0275 a6eb24afbe15eac0a09292f002e82be4 67 Gene3D G3DSA:3.30.700.10 6 62 4.4E-9 T 30-10-2018 phiST2_0275 a6eb24afbe15eac0a09292f002e82be4 67 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 30-10-2018 IPR012902 Prokaryotic N-terminal methylation site phiST2_0275 a6eb24afbe15eac0a09292f002e82be4 67 SUPERFAMILY SSF54523 6 32 2.59E-6 T 30-10-2018 phiST2_0275 a6eb24afbe15eac0a09292f002e82be4 67 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 25 4.4E-7 T 30-10-2018 IPR012902 Prokaryotic N-terminal methylation site phiST2_0226 9f336f946a525eb3163e66cf82690751 163 PIRSF PIRSF004377 1 163 1.6E-50 T 30-10-2018 IPR016415 Bacteriophage T4, Gp68, prohead core phiST2_0263 3281dfab7741e60bb843b494cb9d43ca 274 Pfam PF11637 ATP-dependant DNA helicase UvsW 14 69 2.1E-33 T 30-10-2018 IPR020975 DNA helicase, ATP-dependent, UvsW phiST2_0263 3281dfab7741e60bb843b494cb9d43ca 274 Gene3D G3DSA:1.20.1280.210 2 72 2.0E-9 T 30-10-2018 IPR038341 DNA helicase UvsW superfamily phiST2_0316 7dd888b644b3e6bfaa9458a14a1bcc5b 154 Gene3D G3DSA:1.10.357.40 4 153 4.4E-11 T 30-10-2018 IPR037238 YbiA-like superfamily phiST2_0316 7dd888b644b3e6bfaa9458a14a1bcc5b 154 SUPERFAMILY SSF143990 6 149 4.97E-21 T 30-10-2018 IPR037238 YbiA-like superfamily phiST2_0316 7dd888b644b3e6bfaa9458a14a1bcc5b 154 Pfam PF08010 Bacteriophage protein GP30.3 8 144 3.7E-70 T 30-10-2018 IPR012596 Bacteriophage T4, Y12G phiST2_0010 f47e27809f3860ef41e593e78ff09dc1 328 ProDom PD130832 RIIB EARLY PROTECTOR PROPHAGE-INDUCED MEMBRANE FROM LYSIS DNA-BINDING RIIA-RIIB DNA 136 297 4.0E-72 T 30-10-2018 phiST2_0016 f022f19a0edd445008e9dad32b415f41 161 Gene3D G3DSA:1.10.287.70 1 51 2.9E-10 T 30-10-2018 phiST2_0016 f022f19a0edd445008e9dad32b415f41 161 SUPERFAMILY SSF81324 3 66 2.22E-12 T 30-10-2018 phiST2_0016 f022f19a0edd445008e9dad32b415f41 161 Pfam PF07885 Ion channel 3 45 8.0E-6 T 30-10-2018 IPR013099 Potassium channel domain phiST2_0165 0dbf675dc6b89349d0436f780f8a9672 576 Pfam PF13884 Chaperone of endosialidase 480 530 8.1E-14 T 30-10-2018 IPR030392 Intramolecular chaperone auto-processing domain phiST2_0206 33e2fa16f818a04671dcd895d9f49b30 139 Pfam PF04965 Gene 25-like lysozyme 39 123 1.2E-16 T 30-10-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD phiST2_0206 33e2fa16f818a04671dcd895d9f49b30 139 SUPERFAMILY SSF160719 34 124 8.63E-23 T 30-10-2018 phiST2_0206 33e2fa16f818a04671dcd895d9f49b30 139 Gene3D G3DSA:3.10.450.40 13 138 1.1E-41 T 30-10-2018 phiST2_0252 7423e6f8dba7eace9e4825bb22eed99d 181 PRINTS PR00070 Dihydrofolate reductase signature 18 28 1.2E-10 T 30-10-2018 phiST2_0252 7423e6f8dba7eace9e4825bb22eed99d 181 PRINTS PR00070 Dihydrofolate reductase signature 33 41 1.2E-10 T 30-10-2018 phiST2_0252 7423e6f8dba7eace9e4825bb22eed99d 181 PRINTS PR00070 Dihydrofolate reductase signature 46 57 1.2E-10 T 30-10-2018 phiST2_0252 7423e6f8dba7eace9e4825bb22eed99d 181 PRINTS PR00070 Dihydrofolate reductase signature 109 123 1.2E-10 T 30-10-2018 phiST2_0252 7423e6f8dba7eace9e4825bb22eed99d 181 Pfam PF00186 Dihydrofolate reductase 19 140 3.4E-24 T 30-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 phiST2_0252 7423e6f8dba7eace9e4825bb22eed99d 181 SUPERFAMILY SSF53597 13 153 4.71E-33 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 phiST2_0252 7423e6f8dba7eace9e4825bb22eed99d 181 Gene3D G3DSA:3.40.430.10 2 173 3.3E-38 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 phiST2_0091 dce9d4cee55ccc3aae3217e5e7a8d7ed 326 Pfam PF13521 AAA domain 154 308 3.8E-28 T 30-10-2018 IPR038727 NadR/Ttd14, AAA domain phiST2_0091 dce9d4cee55ccc3aae3217e5e7a8d7ed 326 Gene3D G3DSA:3.40.50.620 2 149 8.3E-22 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold phiST2_0091 dce9d4cee55ccc3aae3217e5e7a8d7ed 326 Gene3D G3DSA:3.40.50.300 152 312 2.1E-27 T 30-10-2018 phiST2_0091 dce9d4cee55ccc3aae3217e5e7a8d7ed 326 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 40 1.5E-8 T 30-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 phiST2_0091 dce9d4cee55ccc3aae3217e5e7a8d7ed 326 SUPERFAMILY SSF52540 151 284 1.43E-7 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase phiST2_0091 dce9d4cee55ccc3aae3217e5e7a8d7ed 326 SUPERFAMILY SSF52374 2 156 3.75E-13 T 30-10-2018 phiST2_0205 7baffc4c58e1088d0d41d5d3486b6b22 291 Pfam PF01145 SPFH domain / Band 7 family 27 216 1.2E-14 T 30-10-2018 IPR001107 Band 7 domain phiST2_0205 7baffc4c58e1088d0d41d5d3486b6b22 291 SUPERFAMILY SSF117892 128 208 1.96E-7 T 30-10-2018 IPR036013 Band 7/SPFH domain superfamily phiST2_0322 10f7b4914f83c13f63c7fb47c85b65a0 69 Pfam PF17470 Phage protein Gp45.2 7 61 5.4E-32 T 30-10-2018 IPR035342 Phage protein Gp45.2 phiST2_0217 d762f6cd35b36cb061b949ab663b00e1 279 Pfam PF11649 Virus neck protein 1 279 2.1E-164 T 30-10-2018 IPR021674 Bacteriophage T4, Gp14, neck protein phiST2_0161 5e9c9583089e26129a6dfa6491bbe84c 99 Gene3D G3DSA:1.10.1810.10 10 95 2.7E-16 T 30-10-2018 IPR036486 Anti-Sigma Factor A superfamily phiST2_0161 5e9c9583089e26129a6dfa6491bbe84c 99 SUPERFAMILY SSF69070 9 98 6.54E-35 T 30-10-2018 IPR036486 Anti-Sigma Factor A superfamily phiST2_0161 5e9c9583089e26129a6dfa6491bbe84c 99 Pfam PF09010 Anti-Sigma Factor A 10 94 1.1E-46 T 30-10-2018 IPR015100 Anti-Sigma Factor A GO:0006355 phiST2_0084 b5fcdddf35d5abe9ad58ec6c3c9ed3ef 134 ProDom PD021350 ENDONUCLEASE PYRIMIDINE GLYCOSYLASE DIMER-SPECIFIC V DNA DENV HYDROLASE V DIMER 6 79 2.0E-36 T 30-10-2018 IPR021143 Pyrimidine dimer DNA glycosylase, endonuclease V type phiST2_0084 b5fcdddf35d5abe9ad58ec6c3c9ed3ef 134 Gene3D G3DSA:1.10.440.10 1 129 4.1E-32 T 30-10-2018 IPR024796 T4 endonuclease V phiST2_0084 b5fcdddf35d5abe9ad58ec6c3c9ed3ef 134 SUPERFAMILY SSF47077 1 124 1.31E-42 T 30-10-2018 phiST2_0084 b5fcdddf35d5abe9ad58ec6c3c9ed3ef 134 Pfam PF03013 Pyrimidine dimer DNA glycosylase 2 127 1.1E-36 T 30-10-2018 IPR004260 Pyrimidine dimer DNA glycosylase phiST2_0379 65c9657e4561bb4af1665a03b1637170 112 SUPERFAMILY SSF50129 2 108 3.67E-41 T 30-10-2018 IPR011032 GroES-like superfamily phiST2_0379 65c9657e4561bb4af1665a03b1637170 112 Pfam PF00166 Chaperonin 10 Kd subunit 5 107 1.1E-17 T 30-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 phiST2_0379 65c9657e4561bb4af1665a03b1637170 112 Gene3D G3DSA:2.30.33.40 1 108 2.0E-41 T 30-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 phiST2_0379 65c9657e4561bb4af1665a03b1637170 112 PIRSF PIRSF004380 1 109 1.3E-47 T 30-10-2018 IPR016416 Bacteriophage T4, Gp31, chaperonin-GroEL phiST2_0317 894ddd71639e5887467e8c65f655ff9e 166 Gene3D G3DSA:3.40.50.1000 50 165 4.5E-28 T 30-10-2018 IPR023214 HAD superfamily phiST2_0317 894ddd71639e5887467e8c65f655ff9e 166 Pfam PF06941 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) 50 147 3.7E-10 T 30-10-2018 IPR010708 5'(3')-deoxyribonucleotidase GO:0008253|GO:0009264 Reactome: R-HSA-73621 phiST2_0317 894ddd71639e5887467e8c65f655ff9e 166 SUPERFAMILY SSF56784 19 161 7.72E-26 T 30-10-2018 IPR036412 HAD-like superfamily phiST2_0125 b7b51d3c5a5af0ad892976b51c4acfe4 109 Pfam PF11750 Protein of unknown function (DUF3307) 7 105 1.1E-7 T 30-10-2018 IPR021737 Bacteriophage phiKZ, Orf197 phiST2_0224 723952252114aa1d2110434ba3eb2e3e 516 Pfam PF07230 Bacteriophage T4-like capsid assembly protein (Gp20) 3 503 6.8E-274 T 30-10-2018 IPR010823 Portal protein Gp20 phiST2_0224 723952252114aa1d2110434ba3eb2e3e 516 Hamap MF_04114 Portal protein. 2 516 35.468 T 30-10-2018 IPR010823 Portal protein Gp20 phiST2_0371 2de29813cb6be5f3be42e4685441dcb2 552 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 237 243 - T 30-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 phiST2_0229 0bdad8e241515c4a99e6a6a835fc1f93 514 Hamap MF_04117 Major capsid protein. 1 514 55.434 T 30-10-2018 IPR038997 Major capsid protein, Myoviridae GO:0019028 phiST2_0229 0bdad8e241515c4a99e6a6a835fc1f93 514 Pfam PF07068 Major capsid protein Gp23 3 495 0.0 T 30-10-2018 IPR010762 Capsid protein, T4-like bacteriophage-like GO:0019012|GO:0019028 phiST2_0288 047c25d68a0fce0af1e6bdf24c503c41 253 SUPERFAMILY SSF52467 2 229 4.67E-46 T 30-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily phiST2_0288 047c25d68a0fce0af1e6bdf24c503c41 253 Pfam PF02146 Sir2 family 8 177 3.1E-26 T 30-10-2018 IPR003000 Sirtuin family GO:0070403 phiST2_0288 047c25d68a0fce0af1e6bdf24c503c41 253 Gene3D G3DSA:3.40.50.1220 3 203 4.8E-42 T 30-10-2018 phiST2_0288 047c25d68a0fce0af1e6bdf24c503c41 253 Gene3D G3DSA:3.30.1600.10 17 147 4.8E-42 T 30-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily phiST2_0207 cb14e8e0f95eb103f9695290114b0f90 652 Hamap MF_04102 Baseplate wedge protein gp6. 1 652 42.293 T 30-10-2018 IPR034698 Baseplate wedge protein gp6 GO:0098025 phiST2_0207 cb14e8e0f95eb103f9695290114b0f90 652 Gene3D G3DSA:3.30.300.200 331 407 5.6E-39 T 30-10-2018 phiST2_0162 be7e9694e5769265e4b1bb875ae9cc81 98 Pfam PF11195 Protein of unknown function (DUF2829) 2 95 3.9E-25 T 30-10-2018 IPR021361 Protein of unknown function DUF2829 phiST2_0143 846ce3370667722960a6ef05daa198a6 99 SUPERFAMILY SSF52833 4 85 1.17E-10 T 30-10-2018 IPR036249 Thioredoxin-like superfamily phiST2_0143 846ce3370667722960a6ef05daa198a6 99 Pfam PF00462 Glutaredoxin 3 76 5.9E-13 T 30-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 phiST2_0143 846ce3370667722960a6ef05daa198a6 99 Gene3D G3DSA:3.40.30.10 1 86 5.3E-20 T 30-10-2018 phiST2_0199 b78793d6f3c3ce2201bc2b1166b872a2 192 ProDom PD106550 WEDGE BASEPLATE GP53 SUBUNIT STRUCTURAL T4 LATE BASE GP53-LIKE PLATE 1 188 2.0E-100 T 30-10-2018 IPR022607 Baseplate wedge protein gp53, bacteriophage T4 phiST2_0199 b78793d6f3c3ce2201bc2b1166b872a2 192 Pfam PF11246 Base plate wedge protein 53 1 189 9.5E-106 T 30-10-2018 IPR022607 Baseplate wedge protein gp53, bacteriophage T4 phiST2_0332 be745595d71e28da52087e94de884097 381 Pfam PF09511 RNA ligase 54 254 6.2E-30 T 30-10-2018 IPR019039 RNA ligase T4 Rnl1, N-terminal phiST2_0332 be745595d71e28da52087e94de884097 381 Gene3D G3DSA:1.10.3550.20 252 377 1.8E-38 T 30-10-2018 phiST2_0332 be745595d71e28da52087e94de884097 381 TIGRFAM TIGR02308 RNA_lig_T4_1: RNA ligase, T4 RnlA family 4 377 4.6E-125 T 30-10-2018 IPR012648 Bacteriophage T4 RNA ligase Rnl1 GO:0003972 phiST2_0366 5a14d944ad6779efdc653e3f6bffd588 150 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 77 112 - T 30-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 phiST2_0366 5a14d944ad6779efdc653e3f6bffd588 150 PIRSF PIRSF006019 2 150 4.2E-51 T 30-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 phiST2_0366 5a14d944ad6779efdc653e3f6bffd588 150 Gene3D G3DSA:3.40.140.10 8 150 5.0E-40 T 30-10-2018 phiST2_0366 5a14d944ad6779efdc653e3f6bffd588 150 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 13 123 6.1E-29 T 30-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain phiST2_0366 5a14d944ad6779efdc653e3f6bffd588 150 SUPERFAMILY SSF53927 10 147 9.35E-39 T 30-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 phiST2_0280 7225ba8f1cb6929643785c1fd6a01851 105 SUPERFAMILY SSF101386 12 98 8.9E-6 T 30-10-2018 phiST2_0155 433661659552b3800c78a987f1477d76 99 SUPERFAMILY SSF55166 15 83 6.83E-7 T 30-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 phiST2_0210 1f0b832c6149b2d12f517b2555c81524 318 Gene3D G3DSA:2.60.40.1680 202 316 7.1E-9 T 30-10-2018 IPR027412 Baseplate structural protein Gp9 C-terminal domain superfamily phiST2_0210 1f0b832c6149b2d12f517b2555c81524 318 Pfam PF07880 Bacteriophage T4 gp9/10-like protein 3 307 1.3E-126 T 30-10-2018 IPR008987 Baseplate structural protein Gp9/Gp10 GO:0019076|GO:0098025 phiST2_0210 1f0b832c6149b2d12f517b2555c81524 318 SUPERFAMILY SSF50017 1 316 1.44E-66 T 30-10-2018 IPR036240 Gp9-like superfamily GO:0019076|GO:0098025 phiST2_0242 32406ddca77b86aa36100484878b0f07 56 Pfam PF10886 Protein of unknown function (DUF2685) 1 55 5.4E-36 T 30-10-2018 IPR024362 Protein of unknown function DUF2685 phiST2_0242 32406ddca77b86aa36100484878b0f07 56 ProDom PD051653 UVSY.-2 T4 UVSW-UVSY UVSY.2-LIKE 4 54 8.0E-21 T 30-10-2018 phiST2_0307 c6daec2ebb7bb61596cd798741aa1086 275 Pfam PF10263 SprT-like family 29 104 1.3E-15 T 30-10-2018 IPR006640 SprT-like phiST2_0179 f604a92f8bbeccfd96b59a7734fd6e5a 571 Gene3D G3DSA:3.30.60.240 16 38 1.4E-5 T 30-10-2018 phiST2_0264 c941983530bfb19b506cc38240ee0674 159 Pfam PF07068 Major capsid protein Gp23 107 146 3.7E-4 T 30-10-2018 IPR010762 Capsid protein, T4-like bacteriophage-like GO:0019012|GO:0019028 phiST2_0227 f9b6f271318919102ec7da930ae8237d 213 ProDom PD111331 PROTEASE PROHEAD CORE GP21 SCAFFOLD GP21-LIKE AUTOCATALYTIC ALTERNATE PRODUCT T4 38 213 6.0E-97 T 30-10-2018 IPR005082 Peptidase U9, T4 prohead protease phiST2_0227 f9b6f271318919102ec7da930ae8237d 213 Pfam PF03420 Prohead core protein serine protease 5 184 4.7E-89 T 30-10-2018 IPR005082 Peptidase U9, T4 prohead protease phiST2_0261 f1527b9044675888297103e2a161b69d 174 SUPERFAMILY SSF56300 1 143 8.26E-14 T 30-10-2018 phiST2_0261 f1527b9044675888297103e2a161b69d 174 Gene3D G3DSA:3.60.21.10 2 167 3.4E-29 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like phiST2_0022 1850657b3725d311b4f4827367a5b740 200 SUPERFAMILY SSF54171 115 159 5.82E-8 T 30-10-2018 IPR016177 DNA-binding domain superfamily GO:0003677 phiST2_0003 fec1ab2b20fad3562a7461e27d993bfd 192 SUPERFAMILY SSF53335 12 153 6.68E-13 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase phiST2_0003 fec1ab2b20fad3562a7461e27d993bfd 192 Gene3D G3DSA:3.40.50.150 15 189 2.9E-9 T 30-10-2018 phiST2_0215 f60154ef56fa2ad06e9f4a8dda36b35b 560 Gene3D G3DSA:1.20.5.320 5 93 2.9E-16 T 30-10-2018 phiST2_0215 f60154ef56fa2ad06e9f4a8dda36b35b 560 SUPERFAMILY SSF58046 8 109 1.0E-26 T 30-10-2018 phiST2_0370 9544d101df62ef689b759a33ba840639 458 Gene3D G3DSA:3.20.20.105 7 251 4.2E-6 T 30-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 phiST2_0374 6484469e377ecea5b980813fcee07ac1 238 Gene3D G3DSA:3.40.50.620 1 221 1.4E-54 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold phiST2_0374 6484469e377ecea5b980813fcee07ac1 238 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 208 1.6E-50 T 30-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 phiST2_0374 6484469e377ecea5b980813fcee07ac1 238 SUPERFAMILY SSF52402 1 224 1.15E-50 T 30-10-2018 phiST2_0374 6484469e377ecea5b980813fcee07ac1 238 Pfam PF06508 Queuosine biosynthesis protein QueC 2 214 1.6E-52 T 30-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 phiST2_0374 6484469e377ecea5b980813fcee07ac1 238 PIRSF PIRSF006293 1 226 4.7E-57 T 30-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 phiST2_0383 b20d56e2d5f724a4a962b974842859c2 335 Gene3D G3DSA:3.30.1490.70 8 228 6.8E-60 T 30-10-2018 phiST2_0383 b20d56e2d5f724a4a962b974842859c2 335 Pfam PF09414 RNA ligase 27 222 2.2E-23 T 30-10-2018 IPR021122 RNA ligase domain, REL/Rln2 phiST2_0383 b20d56e2d5f724a4a962b974842859c2 335 Gene3D G3DSA:1.10.10.1810 242 332 1.5E-29 T 30-10-2018 phiST2_0383 b20d56e2d5f724a4a962b974842859c2 335 TIGRFAM TIGR02307 RNA_lig_RNL2: RNA ligase, Rnl2 family 3 332 4.4E-131 T 30-10-2018 IPR012647 RNA ligase, Rnl2 GO:0003972|GO:0005524|GO:0016874 phiST2_0383 b20d56e2d5f724a4a962b974842859c2 335 Gene3D G3DSA:3.30.470.30 37 164 6.8E-60 T 30-10-2018 phiST2_0383 b20d56e2d5f724a4a962b974842859c2 335 SUPERFAMILY SSF56091 1 229 4.51E-58 T 30-10-2018 phiST2_0306 fb85c06a3610550aa579be0a8f4e21b3 168 ProDom PD097382 ALC HOST INHIBITOR TRANSCRIPTION DNA-BINDING UNF 4 151 4.0E-6 T 30-10-2018 IPR020367 Host transcription inhibitor Alc GO:0039653 phiST2_0306 fb85c06a3610550aa579be0a8f4e21b3 168 Pfam PF17527 Phage ALP protein 1 126 2.1E-24 T 30-10-2018 IPR020367 Host transcription inhibitor Alc GO:0039653 phiST2_0305 667e258b2b2447061148fc1cc80c99f5 532 Gene3D G3DSA:3.90.176.10 283 494 4.7E-9 T 30-10-2018 phiST2_0305 667e258b2b2447061148fc1cc80c99f5 532 Pfam PF03496 ADP-ribosyltransferase exoenzyme 307 474 3.0E-7 T 30-10-2018 IPR003540 ADP ribosyltransferase GO:0005576|GO:0009405 phiST2_0305 667e258b2b2447061148fc1cc80c99f5 532 SUPERFAMILY SSF56399 301 479 1.38E-12 T 30-10-2018 phiST2_0197 bb81797021aeada95ff385f4b2215860 151 Pfam PF08722 TnsA endonuclease N terminal 60 140 3.8E-6 T 30-10-2018 IPR014833 TnsA endonuclease, N-terminal phiST2_0375 ba1a0dad387944c716e4eee49daf87ef 202 Gene3D G3DSA:3.60.20.10 2 201 1.7E-10 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal phiST2_0375 ba1a0dad387944c716e4eee49daf87ef 202 SUPERFAMILY SSF56235 1 177 1.83E-10 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal phiST2_0372 43cba7de7060349f0210d55aff737d75 167 SUPERFAMILY SSF53335 13 94 8.31E-6 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase phiST2_0372 43cba7de7060349f0210d55aff737d75 167 Gene3D G3DSA:3.40.50.150 7 155 4.1E-7 T 30-10-2018 phiST2_0358 00e36a28f11015e2508c2975acd9211c 94 Pfam PF14216 Domain of unknown function (DUF4326) 5 80 4.5E-26 T 30-10-2018 IPR025475 Protein of unknown function DUF4326) phiST2_0218 881e259d2b780dfcd4f733df47c38d1e 353 Pfam PF16724 T4-like virus Myoviridae tail sheath stabiliser 2 230 6.2E-125 T 30-10-2018 IPR031997 Myoviridae tail sheath stabiliser phiST2_0218 881e259d2b780dfcd4f733df47c38d1e 353 Gene3D G3DSA:3.30.2000.40 4 235 2.5E-77 T 30-10-2018 IPR038553 Myoviridae tail sheath stabiliser superfamily phiST2_0198 c41e4d2f7f677e3a155e0a4e29c31476 378 Pfam PF11091 Tail-tube assembly protein 22 340 9.2E-90 T 30-10-2018 IPR024389 Baseplate tail-tube protein gp48, T4-like virus phiST2_0198 c41e4d2f7f677e3a155e0a4e29c31476 378 ProDom PD135082 GP48 BASEPLATE CAP TUBE TAIL GP48-LIKE T4 TAIL-TUBE DIRECT LATE 269 344 2.0E-38 T 30-10-2018 phiST2_0325 0b2670a72dfde6d3133e34412458cd96 163 Gene3D G3DSA:1.20.272.50 33 109 1.0E-15 T 30-10-2018 phiST2_0325 0b2670a72dfde6d3133e34412458cd96 163 Pfam PF16790 Bacteriophage clamp loader A subunit 40 143 6.6E-36 T 30-10-2018 IPR031868 Bacteriophage clamp loader A subunit GO:0003677|GO:0006260 phiST2_0021 c9b1b8bf94984bcaed27304ae79403ce 337 Pfam PF10127 Predicted nucleotidyltransferase 2 97 7.9E-5 T 30-10-2018 IPR018775 Nucleotidyltransferase, predicted phiST2_0265 2151882e0926e867e910b522b72908a8 352 SUPERFAMILY SSF56731 130 265 3.4E-6 T 30-10-2018